locus-tag	class	description
HZZ03_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HZZ03_RS00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HZZ03_RS00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HZZ03_RS00025	ENOG410667J	hydrolase
HZZ03_RS00030	ENOG41074AV	Hok/gef family
HZZ03_RS00035	ENOG4105EMF	GntR family transcriptional regulator
HZZ03_RS00040	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
HZZ03_RS00045	ENOG4108RTU	Aldolase
HZZ03_RS00050	ENOG4105CXK	mandelate racemase muconate lactonizing
HZZ03_RS00055	ENOG4105DJB	Major Facilitator Superfamily
HZZ03_RS00065	ENOG4105C5I	Dehydrogenase
HZZ03_RS00070	ENOG4105D99	atp gtp-binding protein
HZZ03_RS00075	ENOG4105R2A	(LipO)protein
HZZ03_RS00090	ENOG4105FDP	GntR family transcriptional regulator
HZZ03_RS00095	ENOG4105CI1	PTS System
HZZ03_RS00100	ENOG4105F8D	glycoside hydrolase family 4
HZZ03_RS00105	ENOG4105VG5	Membrane
HZZ03_RS00110	ENOG4105JP4	Inner membrane protein yidG
HZZ03_RS00120	ENOG4105E5M	Multidrug resistance protein D
HZZ03_RS00150	ENOG4106VK6	Flagellar motor protein
HZZ03_RS00195	ENOG4108WC9	type VI secretion system effector, hcp1 family
HZZ03_RS00255	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HZZ03_RS00260	ENOG4105D9P	serine threonine protein kinase
HZZ03_RS00275	ENOG4105CS6	Rhs element vgr protein
HZZ03_RS00295	ENOG4105CNA	YD repeat protein
HZZ03_RS00420	ENOG4105CP7	Triose-phosphate isomerase
HZZ03_RS00425	ENOG4105EBK	exported protein
HZZ03_RS00430	ENOG4108VTS	Membrane
HZZ03_RS00435	ENOG4105DP0	ferredoxin-NADP reductase
HZZ03_RS00440	ENOG4105CBT	Fructose-1,6-bisphosphatase
HZZ03_RS00445	ENOG4105E61	Mannitol repressor protein
HZZ03_RS00450	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
HZZ03_RS00455	ENOG4105CTS	PTS system mannitol-specific
HZZ03_RS00460	ENOG4108U78	Glutathione S-transferase
HZZ03_RS00470	ENOG4105EM7	Selenocysteine-specific translation elongation factor
HZZ03_RS00475	ENOG4105C0A	alcohol dehydrogenase
HZZ03_RS00480	ENOG41066F8	ROK family
HZZ03_RS00495	ENOG4105CT4	transporter
HZZ03_RS00505	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
HZZ03_RS00515	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
HZZ03_RS00520	ENOG4108MG3	formate dehydrogenase
HZZ03_RS00525	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HZZ03_RS00535	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HZZ03_RS00550	ENOG4108UMN	azlc family
HZZ03_RS00570	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
HZZ03_RS00575	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
HZZ03_RS00580	ENOG4105C0A	alcohol dehydrogenase
HZZ03_RS00585	ENOG4105C9J	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde (By similarity)
HZZ03_RS00590	ENOG4105DKG	l-rhamnose isomerase
HZZ03_RS00600	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
HZZ03_RS00605	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
HZZ03_RS00610	ENOG4107YRA	Uptake of L-rhamnose across the boundary membrane with the concomitant transport of protons into the cell (symport system) (By similarity)
HZZ03_RS00615	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HZZ03_RS00620	ENOG4108RPX	mosc domain containing protein
HZZ03_RS00625	ENOG4105DMF	Dehydrogenase
HZZ03_RS00630	ENOG41073TP	transcriptional regulator
HZZ03_RS00635	ENOG4105DAA	L-lactate
HZZ03_RS00650	ENOG4108YYI	Protein of unknown function (DUF2810)
HZZ03_RS00660	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HZZ03_RS00665	ENOG4105N4M	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
HZZ03_RS00670	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HZZ03_RS00675	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
HZZ03_RS00680	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HZZ03_RS00685	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
HZZ03_RS00690	ENOG41063M6	Cell Division Protein
HZZ03_RS00695	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ03_RS00700	ENOG4105C25	Primosomal protein n'
HZZ03_RS00705	ENOG4105VFB	Binds the 23S rRNA (By similarity)
HZZ03_RS00710	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
HZZ03_RS00715	ENOG4105C28	cystathionine
HZZ03_RS00720	ENOG4105CFH	Aspartokinase
HZZ03_RS00725	ENOG4105SYT	Methylenetetrahydrofolate reductase
HZZ03_RS00730	ENOG4107SDU	Methyl-accepting chemotaxis
HZZ03_RS00735	ENOG4105DWT	malate dehydrogenase (quinone)
HZZ03_RS00745	ENOG4105GQR	Chaperone
HZZ03_RS00770	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HZZ03_RS00775	ENOG4105CAS	nag kinase
HZZ03_RS00780	ENOG4105CDH	Citrulline--aspartate ligase
HZZ03_RS00785	ENOG4105CH7	arginosuccinase
HZZ03_RS00790	ENOG4105C5Q	Transcriptional regulator
HZZ03_RS00800	ENOG4105EJ2	Transcriptional regulator
HZZ03_RS00805	ENOG4108Y73	Membrane
HZZ03_RS00810	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
HZZ03_RS00815	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HZZ03_RS00865	ENOG4108WFC	UPF0438 protein yifE
HZZ03_RS00870	ENOG4105C0P	Mg chelatase subunit ChlI
HZZ03_RS00885	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
HZZ03_RS00890	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HZZ03_RS00900	ENOG4105C7B	Threonine dehydratase
HZZ03_RS00905	ENOG4105EMY	transcriptional regulator
HZZ03_RS00910	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HZZ03_RS00915	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
HZZ03_RS00920	ENOG4105C4R	Atp-dependent dna helicase
HZZ03_RS00925	ENOG4105C9X	ppx gppa phosphatase
HZZ03_RS00930	ENOG4105C1J	atp-dependent rna helicase
HZZ03_RS00940	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HZZ03_RS00945	ENOG4105ESV	Glycosyl transferase, family 4
HZZ03_RS00950	ENOG4105SFE	lipopolysaccharide biosynthesis protein
HZZ03_RS00955	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HZZ03_RS00960	ENOG4107QQG	Dehydrogenase
HZZ03_RS00965	ENOG4108WJ1	acetyltransferase
HZZ03_RS00970	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HZZ03_RS00975	ENOG4105EGZ	biosynthesis protein
HZZ03_RS00980	ENOG4105F18	Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity)
HZZ03_RS00985	ENOG4105DAD	Could be involved in ECA polysaccharide chain elongation (By similarity)
HZZ03_RS00990	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
HZZ03_RS00995	ENOG4105C85	amino acid
HZZ03_RS01025	ENOG410601J	HemY protein
HZZ03_RS01030	ENOG4105ECF	c-methyltransferase
HZZ03_RS01035	ENOG41076E6	Uroporphyrinogen-III Synthase
HZZ03_RS01040	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HZZ03_RS01045	ENOG4107T0K	Adenylate cyclase
HZZ03_RS01050	ENOG4105XQ6	frataxin-like protein
HZZ03_RS01055	ENOG4105S7Z	(LipO)protein
HZZ03_RS01060	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HZZ03_RS01065	ENOG4105CT0	Protein of unknown function, DUF484
HZZ03_RS01070	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HZZ03_RS01075	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
HZZ03_RS01080	ENOG4105C4R	Atp-dependent dna helicase
HZZ03_RS01085	ENOG4107QUT	magnesium and cobalt transport protein CorA
HZZ03_RS01090	ENOG4105NRM	Membrane
HZZ03_RS01100	ENOG4105FR1	rard protein
HZZ03_RS01105	ENOG4108VUY	thioesterase Superfamily protein
HZZ03_RS01110	ENOG4105HDD	phospholipase
HZZ03_RS01115	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HZZ03_RS01120	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
HZZ03_RS01125	ENOG410829K	Lysine exporter protein (Lyse ygga)
HZZ03_RS01130	ENOG4108EUD	Lysophospholipase
HZZ03_RS01135	ENOG4105DQF	Hydrolase
HZZ03_RS01140	ENOG4105EMK	carboxylate amino acid amine transporter
HZZ03_RS01145	ENOG4105DZ2	Transcriptional regulator
HZZ03_RS01150	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
HZZ03_RS01155	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
HZZ03_RS01160	ENOG4107SXA	Phosphorylase
HZZ03_RS01165	ENOG4105CGY	Dna recombination protein
HZZ03_RS01170	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HZZ03_RS01175	ENOG4105JC1	sterol-binding domain protein
HZZ03_RS01180	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
HZZ03_RS01185	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HZZ03_RS01190	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HZZ03_RS01195	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HZZ03_RS01200	ENOG4105F8V	Hydrolase, tatD family
HZZ03_RS01210	ENOG4105MDZ	Transcriptional activator rfaH
HZZ03_RS01215	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HZZ03_RS01220	ENOG4107QK7	reductase
HZZ03_RS01230	ENOG4105CHU	acetyl-coa acetyltransferase
HZZ03_RS01235	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HZZ03_RS01240	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
HZZ03_RS01245	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HZZ03_RS01250	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HZZ03_RS01255	ENOG4108RR8	protoporphyrinogen oxidase
HZZ03_RS01280	ENOG4105D4A	Cell wall formation (By similarity)
HZZ03_RS01285	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HZZ03_RS01290	ENOG4105CS9	pantothenic acid kinase
HZZ03_RS01315	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HZZ03_RS01320	ENOG4105PM1	preprotein translocase subunit SecE
HZZ03_RS01325	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HZZ03_RS01330	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HZZ03_RS01335	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HZZ03_RS01340	ENOG4108VZM	50s ribosomal protein L10
HZZ03_RS01345	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HZZ03_RS01350	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HZZ03_RS01355	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HZZ03_RS01370	ENOG4105VCP	PTS System
HZZ03_RS01380	ENOG4105D41	biosynthesis protein thiH
HZZ03_RS01385	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HZZ03_RS01390	ENOG4105WHD	thiamine biosynthesis protein ThiS
HZZ03_RS01395	ENOG4105D06	uba thif-type nad fad binding protein
HZZ03_RS01400	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HZZ03_RS01405	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
HZZ03_RS01410	ENOG4107MNS	Has binding activity to the major sigma subunit of RNA polymerase. May be involved in replacement of the RNA polymerase sigma subunit from sigma-70 to sigma-S during the transition from exponential growth to the stationary phase (By similarity)
HZZ03_RS01415	ENOG4105E09	nadh pyrophosphatase
HZZ03_RS01420	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HZZ03_RS01425	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
HZZ03_RS01430	ENOG4105R2J	Conserved Protein
HZZ03_RS01435	ENOG4105K70	DNA-binding protein
HZZ03_RS01440	ENOG4108T8B	Protein of unknown function (DUF1481)
HZZ03_RS01445	ENOG4105C12	Phosphoribosylglycinamide synthetase
HZZ03_RS01450	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HZZ03_RS01485	ENOG4105CDA	abc transporter atp-binding protein
HZZ03_RS01490	ENOG4105DRP	amino acid AbC transporter
HZZ03_RS01495	ENOG4105EZ7	amino acid ABC transporter
HZZ03_RS01505	ENOG4105XCM	membrane LIPOPROTEIN
HZZ03_RS01510	ENOG4105BZS	acriflavin resistance protein
HZZ03_RS01515	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HZZ03_RS01520	ENOG4108XG4	DNA-binding transcriptional regulator
HZZ03_RS01525	ENOG4105BZU	Histidine kinase
HZZ03_RS01535	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HZZ03_RS01545	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HZZ03_RS01550	ENOG4108IA2	Sodium pantothenate symporter
HZZ03_RS01555	ENOG4105RG0	Membrane
HZZ03_RS01560	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HZZ03_RS01565	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HZZ03_RS01570	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HZZ03_RS01575	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
HZZ03_RS01580	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HZZ03_RS01585	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
HZZ03_RS01590	ENOG41062P1	Diguanylate cyclase phosphodiesterase
HZZ03_RS01600	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HZZ03_RS01605	ENOG4105VQ7	Rod shape-determining protein MreD
HZZ03_RS01615	ENOG4105C03	ribonuclease
HZZ03_RS01620	ENOG4105QD6	exported protein
HZZ03_RS01625	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HZZ03_RS01630	ENOG4105CR8	Transcriptional regulator
HZZ03_RS01635	ENOG4105ZQC	membrane protein AaeX
HZZ03_RS01640	ENOG4105Y49	secretion protein, HlyD family
HZZ03_RS01645	ENOG4107Z11	Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell (By similarity)
HZZ03_RS01650	ENOG4105C26	Dehydrogenase
HZZ03_RS01655	ENOG4105UNR	(Barnase) inhibitor
HZZ03_RS01660	ENOG4105RID	UPF0379 protein yhcN
HZZ03_RS01665	ENOG4105RID	UPF0379 protein yhcN
HZZ03_RS01670	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
HZZ03_RS01675	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HZZ03_RS01680	ENOG4105C0H	protease
HZZ03_RS01685	ENOG4105C0H	protease
HZZ03_RS01690	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
HZZ03_RS01695	ENOG4105D6Z	AFG1 family ATPase
HZZ03_RS01700	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HZZ03_RS01710	ENOG4107MKT	Stringent starvation protein a
HZZ03_RS01715	ENOG4105KB2	stringent starvation protein b
HZZ03_RS01720	ENOG4108QBF	Transcriptional regulator
HZZ03_RS01730	ENOG4105JHE	Major Facilitator Superfamily
HZZ03_RS01735	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
HZZ03_RS01740	ENOG4108R66	Conserved Protein
HZZ03_RS01750	ENOG4105BZ8	glutamate synthase
HZZ03_RS01755	ENOG4105CBC	glutamate synthase
HZZ03_RS01760	ENOG4105N5T	Radical SAM Protein
HZZ03_RS01765	ENOG4105BZU	Histidine kinase
HZZ03_RS01770	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
HZZ03_RS01775	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
HZZ03_RS01780	ENOG41080Z8	PHOSPHOCARRIER protein
HZZ03_RS01785	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HZZ03_RS01790	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
HZZ03_RS01795	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
HZZ03_RS01800	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HZZ03_RS01805	ENOG4108IUZ	ABC transporter
HZZ03_RS01810	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
HZZ03_RS01815	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
HZZ03_RS01820	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
HZZ03_RS01825	ENOG4105C2X	Arabinose 5-phosphate isomerase
HZZ03_RS01830	ENOG4105FEU	K -dependent Na -Ca exchanger
HZZ03_RS01835	ENOG4105DHJ	ABC, transporter
HZZ03_RS01840	ENOG4105CY3	ABC transporter, permease
HZZ03_RS01845	ENOG4107PE3	Mammalian cell entry related domain protein
HZZ03_RS01850	ENOG4105E3I	toluene tolerance
HZZ03_RS01855	ENOG4105UE2	Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane
HZZ03_RS01860	ENOG4105VFK	BolA family
HZZ03_RS01865	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HZZ03_RS01870	ENOG4105HVQ	Regulatory factor of maltose metabolism
HZZ03_RS01875	ENOG4105EAH	synthase
HZZ03_RS01885	ENOG4105K46	50S ribosomal protein l27
HZZ03_RS01890	ENOG4105QYV	Membrane
HZZ03_RS01895	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HZZ03_RS01910	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
HZZ03_RS01915	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HZZ03_RS01920	ENOG4105HBR	Rna-binding protein
HZZ03_RS01925	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
HZZ03_RS01930	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HZZ03_RS01935	ENOG4105EEI	dihydropteroate synthase
HZZ03_RS01940	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HZZ03_RS01945	ENOG4105NTZ	Preprotein translocase subunit SecG
HZZ03_RS01960	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HZZ03_RS01965	ENOG4105CHV	Transcription elongation factor NusA
HZZ03_RS01970	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HZZ03_RS01975	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HZZ03_RS01980	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HZZ03_RS01985	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HZZ03_RS01990	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HZZ03_RS02005	ENOG4105C1J	atp-dependent rna helicase
HZZ03_RS02010	ENOG4105CIC	tryptophan-specific transport protein
HZZ03_RS02015	ENOG4105DEN	Luciferase family
HZZ03_RS02035	ENOG4108YYD	acetyltransferase
HZZ03_RS02040	ENOG41082IR	Excinuclease ABC C subunit domain protein
HZZ03_RS02045	ENOG4108ZPB	UPF0306 protein
HZZ03_RS02050	ENOG4107R7Y	intracellular protease Pfpi family
HZZ03_RS02055	ENOG4105K4T	epimerase
HZZ03_RS02060	ENOG4107S21	permease
HZZ03_RS02065	ENOG4105W4M	Transport-associated protein
HZZ03_RS02070	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HZZ03_RS02080	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
HZZ03_RS02085	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HZZ03_RS02095	ENOG4106D80	Uncharacterized protein YhaL
HZZ03_RS02100	ENOG4108CNN	domain protein
HZZ03_RS02105	ENOG4105CWB	LysR family transcriptional Regulator
HZZ03_RS02110	ENOG4105WBN	Transcriptional regulator (LacI family
HZZ03_RS02130	ENOG4105D7K	pfkb domain protein
HZZ03_RS02135	ENOG4105KAF	membrAne
HZZ03_RS02140	ENOG4105CHF	Glutathione S-transferase
HZZ03_RS02145	ENOG4108VBZ	doxx family
HZZ03_RS02150	ENOG4105UMR	response to DNA damage stimulus
HZZ03_RS02170	ENOG4105UMR	response to DNA damage stimulus
HZZ03_RS02175	ENOG4108S1B	Periplasmic chaperone protein
HZZ03_RS02180	ENOG4105E6S	usher protein(
HZZ03_RS02200	ENOG4105YJD	
HZZ03_RS02205	ENOG41090KG	Inner membrane protein YqjE
HZZ03_RS02210	ENOG4105NE1	Conserved Protein
HZZ03_RS02215	ENOG4105WAY	exported protein
HZZ03_RS02220	ENOG4105IYR	Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity)
HZZ03_RS02225	ENOG4106W5V	Membrane
HZZ03_RS02230	ENOG4107YCY	Transcriptional regulator
HZZ03_RS02235	ENOG4105DPW	Major facilitator superfamily MFS_1
HZZ03_RS02240	ENOG4105D2H	Uronic isomerase
HZZ03_RS02245	ENOG4105CTX	dehydratase
HZZ03_RS02250	ENOG4105P66	Membrane
HZZ03_RS02255	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
HZZ03_RS02260	ENOG4105DU1	integral membrane protein, terc
HZZ03_RS02265	ENOG4105EE0	oxidoreductase
HZZ03_RS02270	ENOG4108UB4	uncharacterized protein ygjQ
HZZ03_RS02275	ENOG4108VKG	metal-dependent hydrolase
HZZ03_RS02280	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
HZZ03_RS02285	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HZZ03_RS02290	ENOG4105C8Y	Acetylornithine aminotransferase
HZZ03_RS02295	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
HZZ03_RS02300	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HZZ03_RS02305	ENOG4105C8Q	Methyl-accepting chemotaxis
HZZ03_RS02310	ENOG4105NTW	Transcriptional regulator
HZZ03_RS02315	ENOG4105Q26	Siderophore-interacting protein
HZZ03_RS02320	ENOG4105CCT	upf0313 protein
HZZ03_RS02325	ENOG4105KME	endoribonuclease L-psp
HZZ03_RS02330	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
HZZ03_RS02335	ENOG4105CXT	aspartate transcarbamylase
HZZ03_RS02345	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
HZZ03_RS02350	ENOG4105DBV	ornithine carbamoyltransferase
HZZ03_RS02360	ENOG4105CEU	Arginine dihydrolase
HZZ03_RS02370	ENOG4105XEP	YhcH YjgK YiaL family protein
HZZ03_RS02375	ENOG4105DBV	ornithine carbamoyltransferase
HZZ03_RS02385	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
HZZ03_RS02395	ENOG4108MJ3	acetyltransferase
HZZ03_RS02400	ENOG4108M3P	Membrane
HZZ03_RS02410	ENOG4105MYG	DNA polymerase iii, chi subunit
HZZ03_RS02415	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HZZ03_RS02420	ENOG4108M8S	permease YjgP YjgQ family protein
HZZ03_RS02425	ENOG4108K5H	permease YjgP YjgQ family protein
HZZ03_RS02445	ENOG4105DQ4	alcohol dehydrogenase
HZZ03_RS02450	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HZZ03_RS02495	ENOG4105GMB	type VI secretion system effector, hcp1 family
HZZ03_RS02505	ENOG4106BRA	Membrane
HZZ03_RS02510	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HZZ03_RS02520	ENOG4105FU6	Involved in the degradation and recycling of damaged RNA. It is itself a target for degradation by the ATP-dependent protease La (By similarity)
HZZ03_RS02530	ENOG4107FKK	extracellular solute-binding protein family 1
HZZ03_RS02540	ENOG4105EG2	ABC transporter, permease
HZZ03_RS02550	ENOG4105C4C	beta-galactosidase
HZZ03_RS02555	ENOG4105CI1	PTS System
HZZ03_RS02560	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
HZZ03_RS02565	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ03_RS02575	ENOG4105EFX	secretion protein, HlyD family
HZZ03_RS02590	ENOG4105DDV	Transcriptional regulator (LacI family
HZZ03_RS02595	ENOG4105C5Y	PTS System
HZZ03_RS02600	ENOG4105CS2	ec 3.2.1.21
HZZ03_RS02605	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
HZZ03_RS02610	ENOG4105DZC	cytosine deaminase
HZZ03_RS02625	ENOG4105C8Q	Methyl-accepting chemotaxis
HZZ03_RS02635	ENOG4105BZU	Histidine kinase
HZZ03_RS02645	ENOG4106CVF	DNA replication protein
HZZ03_RS02650	ENOG4108PM0	it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' (By similarity)
HZZ03_RS02655	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HZZ03_RS02660	ENOG4105K56	Transcriptional regulator
HZZ03_RS02665	ENOG4107XM3	UPF0442 protein
HZZ03_RS02670	ENOG4105DWK	Membrane
HZZ03_RS02675	ENOG4108N8T	regulatoR
HZZ03_RS02680	ENOG4108T94	DNA-binding transcriptional activator BglJ
HZZ03_RS02685	ENOG4108UIN	ybak prolyl-trna synthetase associated region
HZZ03_RS02690	ENOG4105CK1	PTS System
HZZ03_RS02695	ENOG4108819	ferric iron reductase
HZZ03_RS02700	ENOG4105BZU	Histidine kinase
HZZ03_RS02705	ENOG4105YBH	Protein of unknown function (DUF1435)
HZZ03_RS02725	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
HZZ03_RS02730	ENOG4108WPU	DNA polymerase III subunit psi
HZZ03_RS02735	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
HZZ03_RS02740	ENOG4105PAD	Hydrolase
HZZ03_RS02745	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HZZ03_RS02750	ENOG4105K3G	Periplasmic Protein
HZZ03_RS02760	ENOG4108NRW	Phospholipase, patatin family
HZZ03_RS02765	ENOG4105EYA	deoxyribonuclease
HZZ03_RS02770	ENOG4105D9N	nucleoside
HZZ03_RS02775	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
HZZ03_RS02780	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
HZZ03_RS02785	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
HZZ03_RS02790	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
HZZ03_RS02795	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
HZZ03_RS02800	ENOG41062Z9	Membrane
HZZ03_RS02805	ENOG4105EAC	phosphoserine phosphatase
HZZ03_RS02810	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HZZ03_RS02815	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
HZZ03_RS02825	ENOG4105JQN	Transcriptional regulator
HZZ03_RS02830	ENOG41090SZ	ABC-2 type transporter
HZZ03_RS02845	ENOG4107VDP	teichoic acid biosynthesis
HZZ03_RS02855	ENOG41084CK	capsule polysaccharide
HZZ03_RS02860	ENOG4105E12	capsule polysaccharide
HZZ03_RS02865	ENOG4107V1M	polysaccharide export protein
HZZ03_RS02870	ENOG4105ECX	polysaccharide export
HZZ03_RS02875	ENOG4105C5H	ABC transporter
HZZ03_RS02880	ENOG4107SC1	transglycosylase
HZZ03_RS02885	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
HZZ03_RS02890	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HZZ03_RS02895	ENOG4105CVJ	phosphoglycerate mutase
HZZ03_RS02900	ENOG4105UEI	Transcriptional Regulator AraC Family
HZZ03_RS02905	ENOG4108RH0	Crea protein
HZZ03_RS02910	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HZZ03_RS02915	ENOG4105EB3	Histidine kinase
HZZ03_RS02920	ENOG4105CT7	inner membrane cred family protein
HZZ03_RS02925	ENOG41065U4	response regulator
HZZ03_RS02935	ENOG4106FVC	RNA methyltransferase
HZZ03_RS02945	ENOG4105CFH	Aspartokinase
HZZ03_RS02950	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
HZZ03_RS02955	ENOG4105D98	threonine synthase
HZZ03_RS02960	ENOG4105D1Q	UPF0246 protein
HZZ03_RS02965	ENOG4105BZG	amino acid carrier protein
HZZ03_RS02970	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HZZ03_RS02975	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HZZ03_RS02985	ENOG4106HK8	GPR1 FUN34 yaaH family protein
HZZ03_RS02990	ENOG4105CFG	Acts as a chaperone (By similarity)
HZZ03_RS02995	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HZZ03_RS03025	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HZZ03_RS03030	ENOG41063Z6	transcriptional regulator, lysR family
HZZ03_RS03040	ENOG4105DTN	riboflavin biosynthesis protein ribF
HZZ03_RS03045	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HZZ03_RS03050	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HZZ03_RS03055	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
HZZ03_RS03060	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HZZ03_RS03065	ENOG4105DU0	nucleoside hydrolase
HZZ03_RS03070	ENOG4105EXG	Transcriptional regulator
HZZ03_RS03075	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HZZ03_RS03085	ENOG4105C8I	hydrolase, family 38
HZZ03_RS03090	ENOG410863U	PTS System
HZZ03_RS03100	ENOG4106KNT	transcriptional regulator
HZZ03_RS03105	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HZZ03_RS03110	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HZZ03_RS03115	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HZZ03_RS03125	ENOG4105M5B	(LipO)protein
HZZ03_RS03135	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HZZ03_RS03140	ENOG4105N14	lysine exporter protein LysE YggA
HZZ03_RS03145	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
HZZ03_RS03150	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HZZ03_RS03155	ENOG4105NWN	ApaG protein
HZZ03_RS03160	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HZZ03_RS03165	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HZZ03_RS03170	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HZZ03_RS03175	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
HZZ03_RS03185	ENOG4105D3G	Pseudouridine synthase
HZZ03_RS03190	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
HZZ03_RS03195	ENOG4105CQ2	DNA polymerase
HZZ03_RS03200	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
HZZ03_RS03205	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
HZZ03_RS03215	ENOG41063TF	transcriptional regulator (AraC
HZZ03_RS03220	ENOG4108KF1	Membrane
HZZ03_RS03225	ENOG4107T0D	ABC, transporter
HZZ03_RS03230	ENOG4106SMU	thiamine transporter membrane protein
HZZ03_RS03250	ENOG4105S8Q	sugar efflux transporter
HZZ03_RS03255	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HZZ03_RS03260	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HZZ03_RS03265	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HZZ03_RS03270	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HZZ03_RS03280	ENOG41064T2	transcriptional regulator, lysR family
HZZ03_RS03285	ENOG4105C7K	acetolactate synthase
HZZ03_RS03290	ENOG4108ZP8	Acetolactate synthase small subunit
HZZ03_RS03295	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
HZZ03_RS03300	ENOG4108V6E	Cell division protein mraZ
HZZ03_RS03305	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HZZ03_RS03310	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HZZ03_RS03315	ENOG4105CJN	penicillin-binding protein
HZZ03_RS03325	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
HZZ03_RS03330	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HZZ03_RS03340	ENOG4105CNI	cell division protein FtsW
HZZ03_RS03345	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HZZ03_RS03350	ENOG4105DFU	Cell wall formation (By similarity)
HZZ03_RS03355	ENOG4105CPF	Cell wall formation (By similarity)
HZZ03_RS03360	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
HZZ03_RS03365	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HZZ03_RS03370	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HZZ03_RS03375	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HZZ03_RS03380	ENOG4108SR7	Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (By similarity)
HZZ03_RS03385	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HZZ03_RS03390	ENOG4105M6F	mutator MutT protein
HZZ03_RS03395	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
HZZ03_RS03400	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
HZZ03_RS03405	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HZZ03_RS03410	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HZZ03_RS03415	ENOG4105D7Q	type ii secretion system
HZZ03_RS03420	ENOG4107QHF	type ii secretion system protein e
HZZ03_RS03425	ENOG4108ZUW	Major pilin subunit
HZZ03_RS03430	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HZZ03_RS03440	ENOG4106A72	regulatory protein AmpE
HZZ03_RS03445	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
HZZ03_RS03450	ENOG4105CT4	transporter
HZZ03_RS03455	ENOG4105C85	amino acid
HZZ03_RS03460	ENOG41073TP	transcriptional regulator
HZZ03_RS03465	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HZZ03_RS03470	ENOG4107QSN	dihydrolipoamide acetyltransferase
HZZ03_RS03475	ENOG4107QN2	dihydrolipoyl dehydrogenase
HZZ03_RS03495	ENOG4107QIJ	Aconitate hydratase 2
HZZ03_RS03505	ENOG4108ZIG	UPF0231 protein
HZZ03_RS03510	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
HZZ03_RS03515	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
HZZ03_RS03520	ENOG4108ZRK	uncharacterized protein yacC
HZZ03_RS03525	ENOG4105E3B	Multicopper oxidase
HZZ03_RS03530	ENOG4105DZG	Dehydrogenase
HZZ03_RS03535	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HZZ03_RS03540	ENOG41077A9	carbonic anhydrase
HZZ03_RS03545	ENOG4105DA5	(ABC) transporter
HZZ03_RS03550	ENOG4105E3A	(ABC) transporter
HZZ03_RS03555	ENOG4107BJW	polysaccharide deacetylase
HZZ03_RS03560	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
HZZ03_RS03565	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HZZ03_RS03570	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HZZ03_RS03575	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HZZ03_RS03580	ENOG4105DJ0	Poly(A) Polymerase
HZZ03_RS03585	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HZZ03_RS03595	ENOG4105PW4	Sugar fermentation stimulation protein homolog
HZZ03_RS03600	ENOG4107XID	2'-5' rna ligase
HZZ03_RS03605	ENOG4105CQ7	ATP-dependent helicase
HZZ03_RS03610	ENOG4105BZ4	penicillin-binding protein
HZZ03_RS03615	ENOG4105E0K	tonB-dependent siderophore receptor
HZZ03_RS03620	ENOG4105E0A	ABC, transporter
HZZ03_RS03625	ENOG4105J76	Periplasmic binding protein
HZZ03_RS03630	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
HZZ03_RS03635	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HZZ03_RS03640	ENOG4105CMQ	Chloride channel
HZZ03_RS03645	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HZZ03_RS03650	ENOG4105EN6	Membrane
HZZ03_RS03660	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
HZZ03_RS03665	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
HZZ03_RS03670	ENOG4105C0H	protease
HZZ03_RS03675	ENOG4108T8E	UPF0325 protein
HZZ03_RS03680	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
HZZ03_RS03685	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
HZZ03_RS03690	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HZZ03_RS03695	ENOG4105CE9	30S ribosomal protein S2
HZZ03_RS03700	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HZZ03_RS03705	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HZZ03_RS03710	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HZZ03_RS03715	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HZZ03_RS03725	ENOG4105KNE	Phosphatidate cytidylyltransferase
HZZ03_RS03730	ENOG4105DZP	Membrane-associated zinc metalloprotease
HZZ03_RS03735	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HZZ03_RS03740	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
HZZ03_RS03745	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HZZ03_RS03750	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HZZ03_RS03755	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HZZ03_RS03765	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HZZ03_RS03770	ENOG4105C0B	DNA polymerase III (alpha subunit)
HZZ03_RS03775	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HZZ03_RS03785	ENOG4105CXN	decarboxylase
HZZ03_RS03790	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
HZZ03_RS03795	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HZZ03_RS03805	ENOG4105M1T	rho-binding antiterminator
HZZ03_RS03810	ENOG4105W1I	UPF0253 protein
HZZ03_RS03815	ENOG4108VWS	Yaeq family
HZZ03_RS03820	ENOG4108YZN	class I peptide chain release factor
HZZ03_RS03825	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
HZZ03_RS03830	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HZZ03_RS03835	ENOG4108R96	Methyltransferase, YaeB family
HZZ03_RS03840	ENOG4108R8X	outer membrane lipoprotein
HZZ03_RS03845	ENOG4105D01	(LipO)protein
HZZ03_RS03850	ENOG4108UMI	ABC transporter, permease
HZZ03_RS03860	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HZZ03_RS03890	ENOG4105CV8	reductase
HZZ03_RS03895	ENOG4105HEI	LysR family (Transcriptional regulator
HZZ03_RS03900	ENOG4107NA1	Endonuclease Exonuclease phosphatase
HZZ03_RS03905	ENOG4105F2W	methyltransferase
HZZ03_RS03910	ENOG4105E9H	Lytic Murein transglycosylase
HZZ03_RS03915	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HZZ03_RS03920	ENOG4105D1A	Methyltransferase
HZZ03_RS03925	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HZZ03_RS03930	ENOG4107RZZ	dna polymerase iii epsilon subunit
HZZ03_RS03940	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
HZZ03_RS03945	ENOG4107QPN	acyl-Coa dehydrogenase
HZZ03_RS03950	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HZZ03_RS03955	ENOG4105E7A	Glutamine amidotransferase
HZZ03_RS03960	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
HZZ03_RS03965	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HZZ03_RS03970	ENOG4105CIN	aminoacyl-histidine dipeptidase
HZZ03_RS03975	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
HZZ03_RS03980	ENOG4105V1F	Fermentation respiration switch protein
HZZ03_RS03985	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
HZZ03_RS03990	ENOG4105FCK	Membrane
HZZ03_RS03995	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HZZ03_RS04000	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HZZ03_RS04010	ENOG4105DFP	Integrase
HZZ03_RS04070	ENOG41089N3	Inherit from COG: cobyrinic Acid a,c-diamide synthase
HZZ03_RS04125	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HZZ03_RS04130	ENOG4105DEF	Extracellular solute-binding protein, family 5
HZZ03_RS04135	ENOG4107VK2	coenzyme PQQ biosynthesis protein PqqF
HZZ03_RS04150	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
HZZ03_RS04165	ENOG4108IGT	Dipeptidase
HZZ03_RS04190	ENOG4105ECQ	AraC Family Transcriptional Regulator
HZZ03_RS04200	ENOG4108UQ8	endoribonuclease L-psp
HZZ03_RS04220	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ03_RS04225	ENOG4105CNT	hydrolase family 2
HZZ03_RS04230	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
HZZ03_RS04235	ENOG4107R1I	NAD-dependent malic enzyme
HZZ03_RS04255	ENOG4108UMI	ABC transporter, permease
HZZ03_RS04260	ENOG4105D01	(LipO)protein
HZZ03_RS04270	ENOG4105PY6	Phenolic acid decarboxylase
HZZ03_RS04290	ENOG4105CMU	LysR family (Transcriptional regulator
HZZ03_RS04295	ENOG4105DZG	Dehydrogenase
HZZ03_RS04300	ENOG4105F4G	Membrane
HZZ03_RS04305	ENOG4105CHH	sulfate transporter
HZZ03_RS04310	ENOG41077A9	carbonic anhydrase
HZZ03_RS04320	ENOG4105D58	Diguanylate phosphodiesterase
HZZ03_RS04330	ENOG4107VIJ	nudix hydrolase
HZZ03_RS04335	ENOG4105N2W	Transcriptional regulator
HZZ03_RS04340	ENOG4105D1S	lipid A biosynthesis
HZZ03_RS04345	ENOG4105D6Z	AFG1 family ATPase
HZZ03_RS04350	ENOG41074AV	Hok/gef family
HZZ03_RS04360	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HZZ03_RS04370	ENOG4108IEG	Formate dehydrogenase Alpha subunit
HZZ03_RS04375	ENOG4108IQI	permease
HZZ03_RS04380	ENOG4107QK5	Homocysteine s-methyltransferase
HZZ03_RS04385	ENOG4106FTQ	Taurine ABC transporter, periplasmic
HZZ03_RS04390	ENOG4108IY8	ABC, transporter
HZZ03_RS04395	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
HZZ03_RS04400	ENOG4105E2B	Taurine dioxygenase
HZZ03_RS04415	ENOG4105D52	delta-aminolevulinic acid dehydratase
HZZ03_RS04420	ENOG4108WTK	competence damage-inducible protein
HZZ03_RS04425	ENOG4108NSE	outer membrane autotransporter barrel
HZZ03_RS04430	ENOG4108PNB	DNA-binding transcriptional regulator
HZZ03_RS04435	ENOG4107R6D	beta-lactam binding protein AmpH
HZZ03_RS04445	ENOG4108DQG	in Escherichia coli SbmA is involved in uptake of microcin J25
HZZ03_RS04450	ENOG4107QS8	(LipO)protein
HZZ03_RS04455	ENOG4105FR5	inner membrane protein YaiY
HZZ03_RS04460	ENOG4105UNH	Membrane
HZZ03_RS04465	ENOG4105CPF	Cell wall formation (By similarity)
HZZ03_RS04475	ENOG4105C6X	Major Facilitator
HZZ03_RS04480	ENOG4105RZQ	Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway (By similarity)
HZZ03_RS04485	ENOG4107QNK	)-transporter
HZZ03_RS04490	ENOG4105II7	pyrroline-5-carboxylate reductase
HZZ03_RS04500	ENOG4107VMU	Membrane
HZZ03_RS04505	ENOG4108UPT	UPF0178 protein
HZZ03_RS04510	ENOG4105G4C	Periplasmic ligand-binding sensor protein
HZZ03_RS04515	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HZZ03_RS04520	ENOG4105SS3	
HZZ03_RS04525	ENOG4105HBA	AroM protein
HZZ03_RS04530	ENOG4105NBK	UPF0345 protein
HZZ03_RS04540	ENOG4105DKQ	ROK family
HZZ03_RS04545	ENOG4105EYH	Exonuclease
HZZ03_RS04550	ENOG4107RH8	nuclease SbcCD subunit D
HZZ03_RS04560	ENOG4105BZU	Histidine kinase
HZZ03_RS04565	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
HZZ03_RS04570	ENOG4105C85	amino acid
HZZ03_RS04575	ENOG4107R28	alpha amylase, catalytic region
HZZ03_RS04590	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
HZZ03_RS04595	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HZZ03_RS04600	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HZZ03_RS04605	ENOG4105VIE	preprotein translocase, subunit YajC
HZZ03_RS04610	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HZZ03_RS04615	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HZZ03_RS04620	ENOG4105DRB	nucleoside-specific channel-forming protein
HZZ03_RS04625	ENOG4108KIC	(LipO)protein
HZZ03_RS04630	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HZZ03_RS04635	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HZZ03_RS04640	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HZZ03_RS04645	ENOG4107YIM	Involved in the transcription termination process (By similarity)
HZZ03_RS04650	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HZZ03_RS04655	ENOG4108ZAI	phosphatidylglycerophosphatase a
HZZ03_RS04660	ENOG4105CPC	Aldo Keto reductase
HZZ03_RS04665	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HZZ03_RS04670	ENOG4105CTB	Polyprenyl synthetase
HZZ03_RS04675	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HZZ03_RS04685	ENOG4107S0N	DJ-1 family
HZZ03_RS04690	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HZZ03_RS04695	ENOG4108VPT	UPF0234 protein
HZZ03_RS04700	ENOG4107RDB	Major Facilitator
HZZ03_RS04705	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HZZ03_RS04710	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
HZZ03_RS04715	ENOG4105CCU	oxidase (Subunit III)
HZZ03_RS04720	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HZZ03_RS04725	ENOG4105E2S	oxidase) subunit II
HZZ03_RS04730	ENOG4105F7F	Chaperone
HZZ03_RS04740	ENOG4105EYM	Major Facilitator superfamily
HZZ03_RS04745	ENOG4105IEY	(LipO)protein
HZZ03_RS04750	ENOG4105M85	Bola protein
HZZ03_RS04755	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HZZ03_RS04765	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HZZ03_RS04770	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HZZ03_RS04775	ENOG4105K70	DNA-binding protein
HZZ03_RS04780	ENOG4105EIN	peptidylprolyl cis-trans isomerase
HZZ03_RS04785	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
HZZ03_RS04790	ENOG4108TGP	Thioesterase superfamily protein
HZZ03_RS04800	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HZZ03_RS04805	ENOG4108NFA	extracellular solute-binding protein
HZZ03_RS04810	ENOG4108AZI	Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) (By similarity)
HZZ03_RS04830	ENOG4108XM1	transcriptional regulator AsnC family
HZZ03_RS04835	ENOG4105BZ1	(ABC) transporter
HZZ03_RS04840	ENOG4105BZ1	(ABC) transporter
HZZ03_RS04845	ENOG4108YZA	Nitrogen regulatory protein pii
HZZ03_RS04850	ENOG4105BZU	Histidine kinase
HZZ03_RS04855	ENOG4105C29	acyl-CoA thioesterase
HZZ03_RS04860	ENOG4108MNP	Glycoprotein polysaccharide metabolism
HZZ03_RS04865	ENOG41080UX	Methyltransferase
HZZ03_RS04875	ENOG4105CYR	Crispr-associated protein, cse1 family
HZZ03_RS04885	ENOG41060M0	Crispr-associated protein, cse4 family
HZZ03_RS04900	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
HZZ03_RS04905	ENOG4105PWE	CRISPR-associated protein cas2
HZZ03_RS04950	ENOG41066DG	(EAL) domain protein
HZZ03_RS04955	ENOG4108UMI	ABC transporter, permease
HZZ03_RS04965	ENOG4105D01	(LipO)protein
HZZ03_RS04975	ENOG4105C8Q	Methyl-accepting chemotaxis
HZZ03_RS04980	ENOG4105NRA	50s ribosomal protein l31 type b
HZZ03_RS04985	ENOG4105YK5	50S ribosomal protein L36
HZZ03_RS04990	ENOG4105GSJ	Inner membrane protein ylaC
HZZ03_RS04995	ENOG4108UW5	maltose o-acetyltransferase
HZZ03_RS05005	ENOG4108UKR	Biofilm formation regulator YbaJ
HZZ03_RS05010	ENOG4105BZS	acriflavin resistance protein
HZZ03_RS05015	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HZZ03_RS05020	ENOG4107XI7	Tetr family transcriptional regulator
HZZ03_RS05025	ENOG4105EGS	Mechanosensitive ion channel
HZZ03_RS05030	ENOG4106428	Protein of unknown function (DUF2496)
HZZ03_RS05035	ENOG4108URS	primosomal replication protein n''
HZZ03_RS05040	ENOG4105WD1	Membrane
HZZ03_RS05045	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HZZ03_RS05050	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HZZ03_RS05055	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HZZ03_RS05065	ENOG4108VCD	Chaperone
HZZ03_RS05070	ENOG4105CW0	outer membrane usher protein
HZZ03_RS05085	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HZZ03_RS05090	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HZZ03_RS05100	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
HZZ03_RS05105	ENOG4107QQ0	gntp family
HZZ03_RS05110	ENOG4105BZW	Glycerate kinase
HZZ03_RS05115	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HZZ03_RS05120	ENOG4107RE1	Inosine-guanosine kinase
HZZ03_RS05125	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HZZ03_RS05130	ENOG4105CGH	5'-nucleotidase
HZZ03_RS05135	ENOG4108Z66	YbaK ebsC protein
HZZ03_RS05140	ENOG4105MBR	gumn family
HZZ03_RS05145	ENOG4105C59	p-type ATPase
HZZ03_RS05150	ENOG4108Z6Z	Transcriptional regulator
HZZ03_RS05165	ENOG4105G5H	Membrane
HZZ03_RS05170	ENOG4107QX8	SPFH domain, Band 7 family protein
HZZ03_RS05175	ENOG4107QR8	Thioredoxin
HZZ03_RS05180	ENOG4105E1F	short-chain dehydrogenase reductase
HZZ03_RS05185	ENOG4108UJV	acyl-CoA thioesterase i
HZZ03_RS05190	ENOG4108I0Y	(ABC) transporter
HZZ03_RS05195	ENOG4105CV6	ABC transporter, permease
HZZ03_RS05200	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
HZZ03_RS05215	ENOG4105C28	cystathionine
HZZ03_RS05220	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HZZ03_RS05225	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HZZ03_RS05230	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HZZ03_RS05235	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HZZ03_RS05240	ENOG4105C8N	cysteinyl-tRNA synthetase
HZZ03_RS05245	ENOG4107P2S	Transcriptional regulator
HZZ03_RS05250	ENOG4105CI1	PTS System
HZZ03_RS05255	ENOG4105WQ3	Rna-binding protein
HZZ03_RS05260	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HZZ03_RS05270	ENOG4108KU3	Integrase
HZZ03_RS05300	ENOG4105KUS	lysozyme
HZZ03_RS05305	ENOG4105SZK	Rz endopeptidase from lambdoid prophage DLP12
HZZ03_RS05360	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HZZ03_RS05370	ENOG4105GQR	Chaperone
HZZ03_RS05375	ENOG4105CW0	outer membrane usher protein
HZZ03_RS05410	ENOG4108ZG0	Ompa motb domain protein
HZZ03_RS05425	ENOG4105CS6	Rhs element vgr protein
HZZ03_RS05450	ENOG4105C8Q	Methyl-accepting chemotaxis
HZZ03_RS05455	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
HZZ03_RS05465	ENOG4108TSE	Transferase
HZZ03_RS05470	ENOG4107RNH	Outer membrane receptor FepA
HZZ03_RS05475	ENOG4105E93	esterase
HZZ03_RS05480	ENOG41085A6	mbth domain-containing protein
HZZ03_RS05485	ENOG4105C0W	non-ribosomal peptide synthetase
HZZ03_RS05490	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
HZZ03_RS05495	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
HZZ03_RS05500	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
HZZ03_RS05505	ENOG4105CHM	Aminotransferase
HZZ03_RS05510	ENOG4105DQS	Transcriptional regulator
HZZ03_RS05515	ENOG4105D3R	alkyl hydroperoxide reductase
HZZ03_RS05520	ENOG4108JU3	Alkyl hydroperoxide reductase
HZZ03_RS05525	ENOG4108U51	Universal stress protein
HZZ03_RS05530	ENOG4105E2A	Dehydrogenase
HZZ03_RS05535	ENOG4105NXH	GreA GreB family elongation factor
HZZ03_RS05540	ENOG4105C6Z	Gluconate
HZZ03_RS05545	ENOG4107T3P	ABC, transporter
HZZ03_RS05565	ENOG4105CG3	alpha amylase, catalytic region
HZZ03_RS05580	ENOG4105KTS	ribonuclease
HZZ03_RS05585	ENOG4105CEE	C4-dicarboxylate transporter
HZZ03_RS05590	ENOG41079UR	PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity)
HZZ03_RS05600	ENOG4107Z6W	Protein CrcB homolog
HZZ03_RS05610	ENOG410607N	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity)
HZZ03_RS05615	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HZZ03_RS05620	ENOG41064T2	transcriptional regulator, lysR family
HZZ03_RS05625	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HZZ03_RS05630	ENOG4108Z43	UPF0250 protein
HZZ03_RS05635	ENOG4105DZ1	carboxypeptidase
HZZ03_RS05640	ENOG4105K6T	rare lipoprotein A
HZZ03_RS05645	ENOG4105CNI	cell division protein FtsW
HZZ03_RS05650	ENOG4105CJN	penicillin-binding protein
HZZ03_RS05655	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HZZ03_RS05660	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HZZ03_RS05665	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HZZ03_RS05670	ENOG4105DJF	DNA polymerase III, delta' subunit
HZZ03_RS05680	ENOG4105C8T	Leucyl-tRNA synthetase
HZZ03_RS05685	ENOG4107PAI	alpha helical protein
HZZ03_RS05690	ENOG4105CDA	abc transporter atp-binding protein
HZZ03_RS05695	ENOG4105DRP	amino acid AbC transporter
HZZ03_RS05700	ENOG4105EAD	ABC transporter
HZZ03_RS05705	ENOG4107RP9	extracellular solute-binding protein, family 3
HZZ03_RS05710	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HZZ03_RS05715	ENOG4108JU5	Magnesium and cobalt efflux protein
HZZ03_RS05720	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HZZ03_RS05725	ENOG4105C9A	Phoh family
HZZ03_RS05730	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HZZ03_RS05735	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HZZ03_RS05775	ENOG4105CAQ	asparagine synthetase
HZZ03_RS05780	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
HZZ03_RS05785	ENOG4105E2R	ROK family
HZZ03_RS05790	ENOG4105CE4	GlcNAc 6-P deacetylase
HZZ03_RS05795	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HZZ03_RS05800	ENOG4105CI1	PTS System
HZZ03_RS05810	ENOG4105CX6	glutaminyL-tRNA synthetase
HZZ03_RS05830	ENOG41090R7	Ferric uptake
HZZ03_RS05835	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
HZZ03_RS05840	ENOG4105NNH	LexA regulated protein
HZZ03_RS05845	ENOG4105EV9	Alpha Beta Hydrolase
HZZ03_RS05850	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
HZZ03_RS05855	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
HZZ03_RS05860	ENOG4105D5Q	Arginine ornithine antiporter
HZZ03_RS05865	ENOG4105CXN	decarboxylase
HZZ03_RS05875	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
HZZ03_RS05880	ENOG4105C08	Histidine kinase
HZZ03_RS05885	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
HZZ03_RS05890	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HZZ03_RS05895	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HZZ03_RS05905	ENOG4105XIQ	Protein of unknown function (DUF2517)
HZZ03_RS05910	ENOG4107SEY	Conserved Protein
HZZ03_RS05915	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HZZ03_RS05920	ENOG4107QNR	UPF0135 protein
HZZ03_RS05925	ENOG4105P4J	Allophanate hydrolase, subunit 1
HZZ03_RS05930	ENOG4107R7A	Allophanate hydrolase subunit 2
HZZ03_RS05935	ENOG4105E7W	lamb ycsf family protein
HZZ03_RS05960	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
HZZ03_RS05965	ENOG4105BZN	citrate synthase
HZZ03_RS05970	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
HZZ03_RS05975	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
HZZ03_RS05980	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HZZ03_RS05985	ENOG4105E33	succinate dehydrogenase
HZZ03_RS05990	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HZZ03_RS05995	ENOG4105C7S	Dehydrogenase
HZZ03_RS06000	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HZZ03_RS06005	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HZZ03_RS06010	ENOG4105FDP	GntR family transcriptional regulator
HZZ03_RS06015	ENOG4105DM4	PTS System
HZZ03_RS06020	ENOG4105C8I	hydrolase, family 38
HZZ03_RS06025	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HZZ03_RS06030	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HZZ03_RS06040	ENOG4105KJB	cyd operon protein YbgE
HZZ03_RS06045	ENOG4107YD3	Thioesterase
HZZ03_RS06050	ENOG4105E02	MotA TolQ exbB proton channel
HZZ03_RS06060	ENOG4108Z82	Cell envelope integrity inner membrane protein TolA
HZZ03_RS06070	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HZZ03_RS06075	ENOG4105UFD	tol-pal system protein YbgF
HZZ03_RS06110	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
HZZ03_RS06115	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
HZZ03_RS06120	ENOG4105PGM	cation diffusion facilitator family transporter
HZZ03_RS06130	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HZZ03_RS06135	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HZZ03_RS06140	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HZZ03_RS06145	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HZZ03_RS06150	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
HZZ03_RS06155	ENOG4105CMR	udp-glucose 4-epimerase
HZZ03_RS06160	ENOG4105DKW	ABC transporter
HZZ03_RS06165	ENOG4105F4R	Transcriptional regulator mode
HZZ03_RS06175	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HZZ03_RS06180	ENOG4105E0C	molybdate abc transporter
HZZ03_RS06190	ENOG4108K4B	hydrolase
HZZ03_RS06195	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
HZZ03_RS06200	ENOG4105NBR	Pectinesterase
HZZ03_RS06205	ENOG4108V1U	phospholipid-binding protein
HZZ03_RS06215	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HZZ03_RS06220	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HZZ03_RS06225	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HZZ03_RS06235	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HZZ03_RS06240	ENOG4108IV0	ABC, transporter
HZZ03_RS06255	ENOG4105CHW	UPF0052 protein
HZZ03_RS06260	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HZZ03_RS06265	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HZZ03_RS06270	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HZZ03_RS06275	ENOG4105M00	molybdopterin converting factor, subunit 1
HZZ03_RS06280	ENOG4108ZAF	Molybdopterin
HZZ03_RS06285	ENOG4105HFZ	Membrane
HZZ03_RS06290	ENOG4107UXM	Membrane
HZZ03_RS06295	ENOG4105DZQ	phospholipase D Transphosphatidylase
HZZ03_RS06300	ENOG4105X23	Endonuclease Exonuclease phosphatase
HZZ03_RS06305	ENOG4105I9U	inner membrane protein ybhQ
HZZ03_RS06310	ENOG4107QWP	ABC-2 type transporter
HZZ03_RS06315	ENOG4107QWP	ABC-2 type transporter
HZZ03_RS06320	ENOG4105CJ1	ABC, transporter
HZZ03_RS06325	ENOG4105D0S	secretion protein (HlyD
HZZ03_RS06330	ENOG4107MVR	Transcriptional regulator
HZZ03_RS06335	ENOG4105C1J	atp-dependent rna helicase
HZZ03_RS06340	ENOG4105CS2	ec 3.2.1.21
HZZ03_RS06345	ENOG4105CS2	ec 3.2.1.21
HZZ03_RS06350	ENOG4105C5Y	PTS System
HZZ03_RS06355	ENOG4105CID	antiterminator
HZZ03_RS06360	ENOG4105DVT	helicase
HZZ03_RS06375	ENOG4105CW0	outer membrane usher protein
HZZ03_RS06380	ENOG4108VCD	Chaperone
HZZ03_RS06385	ENOG4108WDE	Fimbrial protein
HZZ03_RS06390	ENOG4108MTB	glycosyl transferase family
HZZ03_RS06395	ENOG4105VR4	UPF0379 protein ybiJ
HZZ03_RS06400	ENOG4105KSC	Transcriptional regulator, TraR DksA family
HZZ03_RS06405	ENOG4105EW6	flavin reductase domain protein, FMN-binding
HZZ03_RS06410	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
HZZ03_RS06415	ENOG4105D8X	mechanosensitive ion channel
HZZ03_RS06420	ENOG4105CDA	abc transporter atp-binding protein
HZZ03_RS06425	ENOG4105E5Q	amino acid AbC transporter
HZZ03_RS06430	ENOG4107R0W	ABC transporter
HZZ03_RS06435	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
HZZ03_RS06445	ENOG4108T1M	outer membrane protein x
HZZ03_RS06450	ENOG4108I6E	Sulfatase
HZZ03_RS06460	ENOG4105KST	dependent repressor
HZZ03_RS06465	ENOG4105F4P	)-transporter
HZZ03_RS06470	ENOG4105CW7	secretion protein, HlyD family
HZZ03_RS06475	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HZZ03_RS06485	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
HZZ03_RS06490	ENOG4105C5H	ABC transporter
HZZ03_RS06495	ENOG4105CKT	filamentous hemagglutinin
HZZ03_RS06505	ENOG4105DPW	Major facilitator superfamily MFS_1
HZZ03_RS06510	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ03_RS06515	ENOG4105D06	uba thif-type nad fad binding protein
HZZ03_RS06520	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HZZ03_RS06525	ENOG4108JQ6	ABC transporter
HZZ03_RS06530	ENOG4105DEF	Extracellular solute-binding protein, family 5
HZZ03_RS06545	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
HZZ03_RS06550	ENOG4105D8V	Glucose sorbosone dehydrogenase
HZZ03_RS06555	ENOG4108TGY	Glutathione S-transferase
HZZ03_RS06560	ENOG4105DZ1	carboxypeptidase
HZZ03_RS06565	ENOG4107FB0	transcriptional regulator DeoR family
HZZ03_RS06570	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
HZZ03_RS06580	ENOG4107QF7	multi-drug
HZZ03_RS06585	ENOG4108HCJ	Hydrolase
HZZ03_RS06590	ENOG4105I03	Flagellin
HZZ03_RS06595	ENOG4106UW1	Major Facilitator superfamily
HZZ03_RS06600	ENOG4108RFG	Tetr family transcriptional regulator
HZZ03_RS06610	ENOG4105D0C	transport protein
HZZ03_RS06615	ENOG4105GWF	inner membrane protein YbjM
HZZ03_RS06620	ENOG4108DBC	nitroreductase
HZZ03_RS06625	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HZZ03_RS06630	ENOG4108RMJ	sensory transduction regulator
HZZ03_RS06635	ENOG4107RUE	extracellular solute-binding protein family 1
HZZ03_RS06640	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HZZ03_RS06645	ENOG4105F38	ABC transporter, permease
HZZ03_RS06650	ENOG4105D38	putrescine abc transporter
HZZ03_RS06655	ENOG4105RBQ	inner membrane protein ybjO
HZZ03_RS06660	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
HZZ03_RS06665	ENOG4106TNF	Periplasmic binding protein
HZZ03_RS06670	ENOG4105DMR	ABC, transporter
HZZ03_RS06675	ENOG4105GBT	ABC transporter
HZZ03_RS06680	ENOG4106PMH	Extracellular solute-binding protein family 3
HZZ03_RS06685	ENOG4105E5Z	arginine transporter ATP-binding subunit
HZZ03_RS06690	ENOG41064MM	(LipO)protein
HZZ03_RS06695	ENOG4105K8R	UPF0145 protein
HZZ03_RS06700	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HZZ03_RS06705	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
HZZ03_RS06710	ENOG4105C5W	Aldolase
HZZ03_RS06715	ENOG4105C7K	acetolactate synthase
HZZ03_RS06720	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HZZ03_RS06725	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
HZZ03_RS06730	ENOG4105DWU	Membrane
HZZ03_RS06735	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
HZZ03_RS06740	ENOG4108MJ5	VirK protein
HZZ03_RS06745	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HZZ03_RS06755	ENOG4105VEQ	Cold shock protein
HZZ03_RS06760	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HZZ03_RS06765	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HZZ03_RS06770	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HZZ03_RS06775	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HZZ03_RS06780	ENOG4108JJ8	(ABC) transporter
HZZ03_RS06785	ENOG4108JJ9	ABC, transporter
HZZ03_RS06790	ENOG4105C3M	thioredoxin reductase
HZZ03_RS06795	ENOG4105EW9	transcriptional regulator AsnC family
HZZ03_RS06800	ENOG4105CNU	cell division protein FtsK
HZZ03_RS06805	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
HZZ03_RS06810	ENOG4105D1H	recombination factor protein RarA
HZZ03_RS06815	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HZZ03_RS06820	ENOG4108ISG	Major Facilitator
HZZ03_RS06825	ENOG4105F1A	Pyruvate formate-lyase
HZZ03_RS06830	ENOG4105C6N	Formate acetyltransferase
HZZ03_RS06835	ENOG4105TMB	Formate nitrite transporter
HZZ03_RS06840	ENOG4105DDY	UPF0142 protein ycaO
HZZ03_RS06845	ENOG4107VMU	Membrane
HZZ03_RS06850	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HZZ03_RS06855	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HZZ03_RS06860	ENOG4105CAT	Cytidine monophosphate kinase
HZZ03_RS06865	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HZZ03_RS06870	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HZZ03_RS06875	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
HZZ03_RS06880	ENOG4105BZ1	(ABC) transporter
HZZ03_RS06885	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HZZ03_RS06890	ENOG4105T0Z	Conserved Protein
HZZ03_RS06895	ENOG4105W49	UPF0434 protein
HZZ03_RS06900	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HZZ03_RS06905	ENOG4108XM1	transcriptional regulator AsnC family
HZZ03_RS06915	ENOG4107VR7	transferase activity, transferring phosphorus-containing groups
HZZ03_RS06920	ENOG4107S90	membrAne
HZZ03_RS06925	ENOG4106371	Methyltransferase
HZZ03_RS06930	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
HZZ03_RS06935	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
HZZ03_RS06940	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
HZZ03_RS06945	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
HZZ03_RS06950	ENOG4105EAQ	(twin-arginine translocation) pathway signal
HZZ03_RS06955	ENOG4105C5X	domain protein
HZZ03_RS06960	ENOG4105CGF	Aromatic amino acid aminotransferase
HZZ03_RS06965	ENOG4105FCK	Membrane
HZZ03_RS06970	ENOG4105C5S	asparaginyl-tRNA synthetase
HZZ03_RS06975	ENOG4107RH7	Nicotinate phosphoribosyltransferase
HZZ03_RS06980	ENOG4105CD8	aminopeptidase N
HZZ03_RS06985	ENOG4105E2Y	ABC, transporter
HZZ03_RS06990	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HZZ03_RS06995	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
HZZ03_RS07000	ENOG4105GVF	(ABC) transporter
HZZ03_RS07005	ENOG4108UZX	fmn reductase
HZZ03_RS07010	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HZZ03_RS07015	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
HZZ03_RS07020	ENOG4105QVC	MOSC domain-containing protein
HZZ03_RS07025	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HZZ03_RS07030	ENOG4105C5H	ABC transporter
HZZ03_RS07035	ENOG4105F1S	paraquat-inducible protein a
HZZ03_RS07040	ENOG4105DY2	Paraquat-inducible protein b
HZZ03_RS07045	ENOG4108Q2G	(LipO)protein
HZZ03_RS07050	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
HZZ03_RS07055	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
HZZ03_RS07060	ENOG4105DAN	ATP-dependent protease
HZZ03_RS07065	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
HZZ03_RS07070	ENOG4105UYK	outer membrane protein a
HZZ03_RS07075	ENOG4108ZD2	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division (By similarity)
HZZ03_RS07080	ENOG4108RZ1	DNA transformation protein
HZZ03_RS07085	ENOG4105EM2	membrane
HZZ03_RS07090	ENOG410901E	Membrane
HZZ03_RS07095	ENOG41088T4	Helicase IV
HZZ03_RS07100	ENOG4108Z5K	methylglyoxal synthase
HZZ03_RS07105	ENOG4105K4P	CoA-binding domain protein
HZZ03_RS07110	ENOG4105GSS	Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress (By similarity)
HZZ03_RS07115	ENOG4105DR4	Methyltransferase
HZZ03_RS07120	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
HZZ03_RS07130	ENOG4108MN8	Membrane
HZZ03_RS07135	ENOG4108J59	Extracellular solute-binding protein, family 5
HZZ03_RS07160	ENOG4105G2Y	Transcriptional regulator
HZZ03_RS07170	ENOG4105XH3	
HZZ03_RS07175	ENOG4105CS1	NAD(P)H quinone oxidoreductase
HZZ03_RS07180	ENOG4105XF5	Escherichia coli IMT2125 genomic chromosome, IMT2125
HZZ03_RS07185	ENOG4105C2W	permease
HZZ03_RS07190	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
HZZ03_RS07195	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
HZZ03_RS07200	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HZZ03_RS07205	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
HZZ03_RS07210	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
HZZ03_RS07220	ENOG4108R86	Transcriptional regulator
HZZ03_RS07235	ENOG4105C26	Dehydrogenase
HZZ03_RS07240	ENOG4105CK7	Sodium proline symporter
HZZ03_RS07250	ENOG4105D9N	nucleoside
HZZ03_RS07260	ENOG410650H	(LipO)protein
HZZ03_RS07265	ENOG4105DBE	peroxidase
HZZ03_RS07270	ENOG4105D5M	phosphate starvation-inducible protein
HZZ03_RS07280	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
HZZ03_RS07300	ENOG4108VCD	Chaperone
HZZ03_RS07305	ENOG4105CW0	outer membrane usher protein
HZZ03_RS07310	ENOG4105MHR	Fimbrial protein
HZZ03_RS07315	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
HZZ03_RS07320	ENOG4107SSZ	Phosphatase
HZZ03_RS07325	ENOG4107XHZ	cytoplasmic chaperone TorD family protein
HZZ03_RS07330	ENOG4108UQ5	membrane protein YcdZ
HZZ03_RS07340	ENOG4108UVJ	appr-1-p processing domain protein
HZZ03_RS07345	ENOG4107RZC	phospholipase d
HZZ03_RS07360	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
HZZ03_RS07365	ENOG4105NAC	(LipO)protein
HZZ03_RS07370	ENOG4108W47	Acidic protein msyB
HZZ03_RS07375	ENOG4105D1S	lipid A biosynthesis
HZZ03_RS07380	ENOG4105C72	UPF0176 protein
HZZ03_RS07385	ENOG4108YYC	ycei family
HZZ03_RS07390	ENOG4105DS1	cytochrome b561
HZZ03_RS07400	ENOG4105PVA	Biofilm formation regulatory protein BssS
HZZ03_RS07405	ENOG4105MEA	DNA damage-inducible protein i
HZZ03_RS07410	ENOG4105EKE	dihydroorotase
HZZ03_RS07415	ENOG4105F3T	(LipO)protein
HZZ03_RS07420	ENOG4105E9S	glutaredoxin 2
HZZ03_RS07425	ENOG4105EV4	Multidrug resistance protein mdtH
HZZ03_RS07430	ENOG4105D9U	N-acetyltransferase
HZZ03_RS07435	ENOG4108YXG	UPF0502 protein
HZZ03_RS07440	ENOG4105EP9	oxidoreductase
HZZ03_RS07445	ENOG4105CJR	Integral membrane protein (MviN
HZZ03_RS07450	ENOG4105QVD	Flagella synthesis protein FlgN
HZZ03_RS07455	ENOG4105M9M	anti-sigma28 factor FlgM
HZZ03_RS07460	ENOG4105CKS	Flagella basal body P-ring formation protein flgA
HZZ03_RS07465	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
HZZ03_RS07470	ENOG4108ZC9	flagellar basal-body rod protein flgc
HZZ03_RS07475	ENOG4105W00	Flagellar hook capping protein
HZZ03_RS07480	ENOG4105BZE	flagellar hook protein, FlgE
HZZ03_RS07485	ENOG4108KPB	Flagellar basal-body rod protein FlgF
HZZ03_RS07490	ENOG4105CGA	flagellar basal-body rod protein FlgG
HZZ03_RS07500	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HZZ03_RS07505	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HZZ03_RS07510	ENOG4105E1Q	flagellar hook-associated protein
HZZ03_RS07515	ENOG4105DTJ	flagellar hook-associated protein
HZZ03_RS07520	ENOG4105EQ0	Major Facilitator superfamily
HZZ03_RS07530	ENOG4107QQB	Ribonuclease E
HZZ03_RS07535	ENOG4105EI2	Pseudouridine synthase
HZZ03_RS07540	ENOG4106JH6	(LipO)protein
HZZ03_RS07545	ENOG4108UHJ	MAF-like protein
HZZ03_RS07550	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
HZZ03_RS07555	ENOG4105VGS	50s ribosomal protein l32
HZZ03_RS07560	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HZZ03_RS07565	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HZZ03_RS07570	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HZZ03_RS07575	ENOG4105CHR	reductase
HZZ03_RS07580	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HZZ03_RS07585	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HZZ03_RS07590	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
HZZ03_RS07595	ENOG4105HHA	aminodeoxychorismate lyase
HZZ03_RS07600	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HZZ03_RS07605	ENOG4107QRG	dna polymerase iii
HZZ03_RS07610	ENOG4105F8V	Hydrolase, tatD family
HZZ03_RS07615	ENOG4105CI1	PTS System
HZZ03_RS07620	ENOG4105CNM	Receptor
HZZ03_RS07625	ENOG4105K59	histidine triad (HIT) protein
HZZ03_RS07630	ENOG41090DQ	Lipoprotein
HZZ03_RS07640	ENOG4108RUM	thiamine kinase
HZZ03_RS07645	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
HZZ03_RS07650	ENOG4105D0Y	UPF0227 protein
HZZ03_RS07655	ENOG4105CEP	NADH dehydrogenase
HZZ03_RS07660	ENOG4107MBR	17 kDa surface antigen
HZZ03_RS07665	ENOG4108IND	Tetr family transcriptional regulator
HZZ03_RS07670	ENOG4105RC8	Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction
HZZ03_RS07675	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
HZZ03_RS07680	ENOG4108JA2	transcriptioN-repair coupling factor
HZZ03_RS07685	ENOG4105D60	lipoprotein releasing system transmembrane protein
HZZ03_RS07690	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HZZ03_RS07695	ENOG4105D60	lipoprotein releasing system transmembrane protein
HZZ03_RS07700	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
HZZ03_RS07705	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HZZ03_RS07710	ENOG4107RUE	extracellular solute-binding protein family 1
HZZ03_RS07715	ENOG4105D38	putrescine abc transporter
HZZ03_RS07735	ENOG4105EZE	Cupin 4 family protein
HZZ03_RS07740	ENOG4105IFJ	Histidine kinase
HZZ03_RS07745	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HZZ03_RS07750	ENOG4107QTF	adenylosuccinate lyase
HZZ03_RS07755	ENOG41075W9	High frequency lysogenization protein HflD homolog
HZZ03_RS07760	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HZZ03_RS07765	ENOG4105C8Q	Methyl-accepting chemotaxis
HZZ03_RS07780	ENOG4108HMX	isocitrate dehydrogenase (NADP)
HZZ03_RS07800	ENOG4105CC0	LysR family Transcriptional regulator
HZZ03_RS07820	ENOG4105C8Q	Methyl-accepting chemotaxis
HZZ03_RS07835	ENOG4105WPN	DNA integration recombination invertion protein
HZZ03_RS07840	ENOG4105VEQ	Cold shock protein
HZZ03_RS07875	ENOG4108MJ5	VirK protein
HZZ03_RS07885	ENOG4105K78	MarR family Transcriptional regulator
HZZ03_RS07890	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HZZ03_RS07895	ENOG4105DJ2	Major Facilitator Superfamily
HZZ03_RS07900	ENOG4108VMM	UPF0756 membrane protein
HZZ03_RS07905	ENOG4108KXH	Ybak prolyl-tRNA synthetase associated
HZZ03_RS07915	ENOG41066DG	(EAL) domain protein
HZZ03_RS07920	ENOG4106AKX	UPF0229 protein
HZZ03_RS07925	ENOG4105CYN	Serine protein kinase
HZZ03_RS07930	ENOG4105GNX	MltA-interacting MipA family protein
HZZ03_RS07935	ENOG4105DSB	aldose 1-epimerase
HZZ03_RS07940	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HZZ03_RS07950	ENOG4105VUT	cytoplasmic protein
HZZ03_RS07955	ENOG4108RWI	nicotinamidase
HZZ03_RS07960	ENOG4105HDK	L-asparaginase
HZZ03_RS07965	ENOG4105D07	Signal peptide peptidase, SppA
HZZ03_RS07970	ENOG41069NU	Nitroreductase
HZZ03_RS07975	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
HZZ03_RS07980	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HZZ03_RS07985	ENOG4105MTM	Protein of unknown function (DUF1496)
HZZ03_RS07990	ENOG4105M6F	mutator MutT protein
HZZ03_RS07995	ENOG4105CGK	Exodeoxyribonuclease III
HZZ03_RS08005	ENOG4105F4X	arginine
HZZ03_RS08010	ENOG4105C26	Dehydrogenase
HZZ03_RS08015	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
HZZ03_RS08025	ENOG4108SPG	Periplasmic Protein
HZZ03_RS08030	ENOG41090B9	response to stress
HZZ03_RS08035	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
HZZ03_RS08045	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
HZZ03_RS08050	ENOG4105KKI	DNA-binding transcriptional activator OsmE
HZZ03_RS08055	ENOG4105CH6	catalase
HZZ03_RS08060	ENOG4105R8J	Activates the cell division inhibited by chromosomal DNA over-replication (By similarity)
HZZ03_RS08070	ENOG41081XE	plasmid maintenance system antidote protein, xre family
HZZ03_RS08075	ENOG4108ETY	sodium dicarboxylate symporter
HZZ03_RS08080	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
HZZ03_RS08085	ENOG4105CHR	reductase
HZZ03_RS08090	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
HZZ03_RS08095	ENOG4107PN8	YfeABCD locus regulator
HZZ03_RS08105	ENOG4105P10	Uncharacterized protein ydiZ
HZZ03_RS08110	ENOG4105DE4	1-phosphofructokinase
HZZ03_RS08115	ENOG4108NE3	Salt-induced outer membrane protein
HZZ03_RS08125	ENOG4105CSH	Transporter
HZZ03_RS08155	ENOG4105KD7	acetyltransferase
HZZ03_RS08165	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HZZ03_RS08170	ENOG41082NX	50s ribosomal protein l35
HZZ03_RS08175	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HZZ03_RS08185	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HZZ03_RS08195	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HZZ03_RS08200	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
HZZ03_RS08205	ENOG4108V06	Glutathione peroxidase
HZZ03_RS08215	ENOG4108QBX	(LipO)protein
HZZ03_RS08220	ENOG4105CK1	PTS System
HZZ03_RS08225	ENOG4105F8D	glycoside hydrolase family 4
HZZ03_RS08230	ENOG41060NJ	transcriptional regulator
HZZ03_RS08235	ENOG4108TC0	Diguanylate phosphodiesterase
HZZ03_RS08240	ENOG4105CNG	UPF0061 protein
HZZ03_RS08245	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HZZ03_RS08250	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
HZZ03_RS08255	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
HZZ03_RS08260	ENOG4105CT4	transporter
HZZ03_RS08275	ENOG4105IPI	Membrane
HZZ03_RS08280	ENOG4105CQB	FAD linked oxidase domain protein
HZZ03_RS08285	ENOG4105KA0	thioesterase Superfamily protein
HZZ03_RS08290	ENOG4105D6F	Phosphatase
HZZ03_RS08295	ENOG4108Z4V	iron-sulfur cluster assembly
HZZ03_RS08300	ENOG4105DIW	FeS assembly protein SUFB
HZZ03_RS08305	ENOG4105C3K	feS assembly ATPase SufC
HZZ03_RS08310	ENOG4105JRK	feS assembly protein SufD
HZZ03_RS08315	ENOG4105C9B	Cysteine desulfurase
HZZ03_RS08320	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HZZ03_RS08335	ENOG4105CA9	Pyruvate kinase
HZZ03_RS08345	ENOG4105F4K	antigen 43
HZZ03_RS08345	ENOG4105F4K	antigen 43
HZZ03_RS08350	ENOG4105CJP	fad dependent oxidoreductase
HZZ03_RS08355	ENOG4105C26	Dehydrogenase
HZZ03_RS08360	ENOG4107VRI	Transcriptional regulator
HZZ03_RS08365	ENOG4108Z86	Glutamine amidotransferase
HZZ03_RS08370	ENOG4105CFQ	glutamine synthetase
HZZ03_RS08375	ENOG4105CUB	amino acid
HZZ03_RS08380	ENOG4108JUA	Transcriptional regulator
HZZ03_RS08385	ENOG4105C45	hydrogenase expression formation protein (HypE)
HZZ03_RS08390	ENOG4105CQS	hydrogenase expression formation protein HypD
HZZ03_RS08395	ENOG41083WG	hydrogenase assembly chaperone
HZZ03_RS08400	ENOG4107RSS	Hydrogenase accessory protein HypB
HZZ03_RS08405	ENOG410816D	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
HZZ03_RS08410	ENOG4108VRC	Formate hydrogenlyase regulatory protein hycA
HZZ03_RS08415	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
HZZ03_RS08420	ENOG4107R30	NADH dehydrogenase
HZZ03_RS08425	ENOG4107TDF	Formate hydrogenlyase subunit 4
HZZ03_RS08430	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HZZ03_RS08435	ENOG4108RG7	formate hydrogenlyase complex iron-sulfur subunit
HZZ03_RS08440	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
HZZ03_RS08445	ENOG4105I6X	formate hydrogenlyase maturation
HZZ03_RS08450	ENOG4108MG9	hydrogenase 3 maturation protease
HZZ03_RS08460	ENOG4108RC0	Electron transport protein
HZZ03_RS08465	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HZZ03_RS08470	ENOG4105C8H	hydrogenase maturation protein Hypf
HZZ03_RS08490	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HZZ03_RS08510	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
HZZ03_RS08520	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
HZZ03_RS08525	ENOG4105C94	Transporter
HZZ03_RS08625	ENOG4107QI1	Mate efflux family protein
HZZ03_RS08630	ENOG4108R6K	riboflavin synthase, subunit alpha
HZZ03_RS08640	ENOG4105CS2	ec 3.2.1.21
HZZ03_RS08645	ENOG4105CK1	PTS System
HZZ03_RS08650	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HZZ03_RS08655	ENOG4105CZQ	inner membrane transport protein YdhC
HZZ03_RS08660	ENOG4105F52	Transcriptional regulator
HZZ03_RS08665	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ03_RS08675	ENOG4105F27	Major Facilitator
HZZ03_RS08680	ENOG4105K4H	Nlp p60 protein
HZZ03_RS08685	ENOG4105M2J	Glutaredoxin
HZZ03_RS08690	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
HZZ03_RS08695	ENOG4108UYE	Lactoylglutathione lyase
HZZ03_RS08700	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HZZ03_RS08705	ENOG4108WUH	Transcriptional regulator, TetR family
HZZ03_RS08710	ENOG4105DIJ	Phosphoethanolamine transferase
HZZ03_RS08715	ENOG4105XZD	Fe-S protein
HZZ03_RS08720	ENOG4107RGM	aldo keto reductase
HZZ03_RS08725	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HZZ03_RS08730	ENOG4105DSW	Fusaric acid resistance protein
HZZ03_RS08735	ENOG4105Y49	secretion protein, HlyD family
HZZ03_RS08750	ENOG4108XTF	Outer Membrane Lipoprotein
HZZ03_RS08755	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HZZ03_RS08760	ENOG410642K	Lysozyme inhibitor
HZZ03_RS08765	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HZZ03_RS08770	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HZZ03_RS08775	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
HZZ03_RS08780	ENOG4108K3A	Glutathione S-transferase
HZZ03_RS08790	ENOG4105CSM	endonuclease III
HZZ03_RS08795	ENOG4105DZB	Electron transport complex
HZZ03_RS08800	ENOG4108UQQ	Electron transport complex
HZZ03_RS08805	ENOG4105D6A	Electron transport complex
HZZ03_RS08810	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
HZZ03_RS08815	ENOG4108R3D	Electron transport complex
HZZ03_RS08820	ENOG4105DGN	Electron transport complex
HZZ03_RS08825	ENOG4105M9B	inner membrane protein ydgK
HZZ03_RS08830	ENOG4105QZ5	OriC-binding nucleoid-associated protein
HZZ03_RS08840	ENOG4105D9R	oxidoreductase
HZZ03_RS08845	ENOG4105DHU	Bile acid
HZZ03_RS08850	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HZZ03_RS08855	ENOG4105C87	Aminotransferase class I and II
HZZ03_RS08860	ENOG4105CI1	PTS System
HZZ03_RS08865	ENOG4107P2S	Transcriptional regulator
HZZ03_RS08870	ENOG4106EAR	Fimbrial protein
HZZ03_RS08875	ENOG4108VCD	Chaperone
HZZ03_RS08880	ENOG4105CW0	outer membrane usher protein
HZZ03_RS08890	ENOG4108T65	Fimbrial
HZZ03_RS08895	ENOG4108T65	Fimbrial
HZZ03_RS08905	ENOG4106J39	exported protein
HZZ03_RS08910	ENOG4105EIP	mannose-6-phosphate isomerase
HZZ03_RS08915	ENOG4107GFK	fumarate
HZZ03_RS08920	ENOG4105C9Q	fumarate hydratase class II
HZZ03_RS08925	ENOG4105KR1	Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity)
HZZ03_RS08930	ENOG4105JJR	Histidine kinase
HZZ03_RS08935	ENOG4105JQN	Transcriptional regulator
HZZ03_RS08940	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
HZZ03_RS08945	ENOG4107EXC	regulatoR
HZZ03_RS08955	ENOG4105D5Q	Arginine ornithine antiporter
HZZ03_RS08960	ENOG4105C5D	exported protein
HZZ03_RS08965	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HZZ03_RS08970	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HZZ03_RS08975	ENOG4105Q9Y	Universal stress protein
HZZ03_RS08980	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
HZZ03_RS08985	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HZZ03_RS08990	ENOG4108DG9	Smr protein MutS2
HZZ03_RS08995	ENOG4108HCJ	Hydrolase
HZZ03_RS09010	ENOG4108JQ5	ABC transporter
HZZ03_RS09015	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HZZ03_RS09040	ENOG4105CT4	transporter
HZZ03_RS09045	ENOG410814C	multidrug resistance protein
HZZ03_RS09060	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HZZ03_RS09065	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HZZ03_RS09070	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HZZ03_RS09075	ENOG4107TYH	extracellular solute-binding protein family 1
HZZ03_RS09080	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HZZ03_RS09085	ENOG4105D81	ABC transporter, permease
HZZ03_RS09090	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
HZZ03_RS09095	ENOG4105C26	Dehydrogenase
HZZ03_RS09135	ENOG4107QY8	reductase
HZZ03_RS09140	ENOG4105QAX	Iron-sulfur
HZZ03_RS09145	ENOG4107KGK	dmso reductase anchor subunit
HZZ03_RS09160	ENOG4105C8Q	Methyl-accepting chemotaxis
HZZ03_RS09190	ENOG4105DEF	Extracellular solute-binding protein, family 5
HZZ03_RS09195	ENOG4105R71	cytoplasmic protein
HZZ03_RS09200	ENOG4106KE4	Dehydrogenase
HZZ03_RS09205	ENOG4108T9Y	Inner membrane protein ydcZ
HZZ03_RS09210	ENOG4108Z7F	N-acetyltransferase
HZZ03_RS09220	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HZZ03_RS09240	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HZZ03_RS09255	ENOG4108WYP	Transcriptional regulator
HZZ03_RS09265	ENOG4105C8Q	Methyl-accepting chemotaxis
HZZ03_RS09270	ENOG4107GJV	short-chain dehydrogenase reductase
HZZ03_RS09285	ENOG41084S7	Plasmid maintenance system antidote protein
HZZ03_RS09290	ENOG4105CHB	tonB-dependent Receptor
HZZ03_RS09295	ENOG4108NS2	receptor
HZZ03_RS09300	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
HZZ03_RS09325	ENOG4105C85	amino acid
HZZ03_RS09335	ENOG4108RCM	Nitroreductase
HZZ03_RS09340	ENOG4105WBD	4-oxalocrotonate tautomerase
HZZ03_RS09345	ENOG4105WEF	catalase
HZZ03_RS09350	ENOG4108N8X	transition metal ion binding
HZZ03_RS09355	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
HZZ03_RS09370	ENOG4105DQ4	alcohol dehydrogenase
HZZ03_RS09375	ENOG4105CHR	reductase
HZZ03_RS09400	ENOG4105EMU	Dehydrogenase
HZZ03_RS09405	ENOG4105CF7	AraC family transcriptional regulator
HZZ03_RS09425	ENOG4105D58	Diguanylate phosphodiesterase
HZZ03_RS09445	ENOG4108QBX	(LipO)protein
HZZ03_RS09450	ENOG4108Z4X	TRANSCRIPTIONal
HZZ03_RS09455	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
HZZ03_RS09475	ENOG4105RHY	Pfam:UPF0157
HZZ03_RS09525	ENOG4105BZU	Histidine kinase
HZZ03_RS09545	ENOG4107QZW	Altronate oxidoreductase
HZZ03_RS09555	ENOG4105BZU	Histidine kinase
HZZ03_RS09560	ENOG4105BZU	Histidine kinase
HZZ03_RS09565	ENOG4105BZU	Histidine kinase
HZZ03_RS09570	ENOG4105M0C	cytoplasmic protein
HZZ03_RS09575	ENOG4105CSV	Glutaminase
HZZ03_RS09580	ENOG4105C8Q	Methyl-accepting chemotaxis
HZZ03_RS09585	ENOG4105C26	Dehydrogenase
HZZ03_RS09590	ENOG4105EGI	Transcriptional regulator
HZZ03_RS09600	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HZZ03_RS09605	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HZZ03_RS09610	ENOG4105F27	Major Facilitator
HZZ03_RS09615	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
HZZ03_RS09620	ENOG4108XW0	May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF
HZZ03_RS09625	ENOG4106DNR	multiple antibiotic resistance protein
HZZ03_RS09630	ENOG4108594	Permease of the drug metabolite transporter
HZZ03_RS09635	ENOG4105E5W	Transporter
HZZ03_RS09695	ENOG4105DAX	Pfam:DUF2983
HZZ03_RS09725	ENOG4108M24	von Willebrand factor, type A
HZZ03_RS09730	ENOG4108M24	von Willebrand factor, type A
HZZ03_RS09765	ENOG4108IV0	ABC, transporter
HZZ03_RS09770	ENOG4105C0Z	ABC transporter
HZZ03_RS09775	ENOG4105CNN	ABC, transporter
HZZ03_RS09780	ENOG4105C32	Amino acid ABC transporter (Permease)
HZZ03_RS09820	ENOG4105XF5	Escherichia coli IMT2125 genomic chromosome, IMT2125
HZZ03_RS09830	ENOG4105FFC	UPF0187 protein
HZZ03_RS09845	ENOG4105DGW	oligopeptidase A
HZZ03_RS09850	ENOG4105EMU	Dehydrogenase
HZZ03_RS09855	ENOG4107XBN	GntR Family Transcriptional Regulator
HZZ03_RS09865	ENOG41061EV	selenium-binding protein YdfZ
HZZ03_RS09870	ENOG4105DEI	Mannitol dehydrogenase
HZZ03_RS09875	ENOG4105DPW	Major facilitator superfamily MFS_1
HZZ03_RS09880	ENOG4105CXK	mandelate racemase muconate lactonizing
HZZ03_RS09885	ENOG4105KK4	UPF0060 membrane protein
HZZ03_RS09890	ENOG4105M5Q	UPF0482 protein
HZZ03_RS09895	ENOG4108MK9	spermidine N(1)-acetyltransferase
HZZ03_RS09905	ENOG4105KBG	Protein of unknown function (DUF1161)
HZZ03_RS09910	ENOG4107QY8	reductase
HZZ03_RS09915	ENOG4105QAX	Iron-sulfur
HZZ03_RS09920	ENOG4107KGK	dmso reductase anchor subunit
HZZ03_RS09925	ENOG4108NEM	leader-binding protein dmsD
HZZ03_RS09930	ENOG4105RA2	Membrane
HZZ03_RS09935	ENOG4108U0I	binding-protein-dependent transport systems inner membrane Component
HZZ03_RS09940	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
HZZ03_RS09945	ENOG4105E90	ABC transporter
HZZ03_RS09950	ENOG4108IJ8	ABC transporter
HZZ03_RS09955	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HZZ03_RS09960	ENOG4105DAG	ROK family
HZZ03_RS09965	ENOG4106NZI	LysR family Transcriptional regulator
HZZ03_RS09970	ENOG4105D94	Major Facilitator Superfamily
HZZ03_RS09975	ENOG4105CTD	carboxy-peptidase
HZZ03_RS09980	ENOG4105CVW	peptidase s1 and s6 chymotrypsin hap
HZZ03_RS09985	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
HZZ03_RS09990	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
HZZ03_RS10000	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HZZ03_RS10005	ENOG4105KT5	UmuD protein
HZZ03_RS10010	ENOG4105CFP	Peptidase U32
HZZ03_RS10015	ENOG4108JCI	Transcriptional regulator
HZZ03_RS10020	ENOG4105DKK	Benzoate
HZZ03_RS10030	ENOG4105SZK	Rz endopeptidase from lambdoid prophage DLP12
HZZ03_RS10035	ENOG4105NVB	glycoside hydrolase, family 19
HZZ03_RS10050	ENOG4105IHM	Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity)
HZZ03_RS10055	ENOG4105CKK	Glycosyl transferase, family 2
HZZ03_RS10205	ENOG4108PM0	it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' (By similarity)
HZZ03_RS10235	ENOG41076J9	exonuclease VIII
HZZ03_RS10280	ENOG41088CC	tellurite resistance protein tehB
HZZ03_RS10285	ENOG4107WE3	acetyltransferase YdcK
HZZ03_RS10290	ENOG4108Z9I	-acetyltransferase
HZZ03_RS10295	ENOG4105DJ9	glucan biosynthesis protein
HZZ03_RS10305	ENOG4105E32	cytoplasmic protein
HZZ03_RS10315	ENOG4105DDW	LysR family Transcriptional regulator
HZZ03_RS10320	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HZZ03_RS10325	ENOG4108Z9Z	response to DNA damage stimulus
HZZ03_RS10330	ENOG4105C8Q	Methyl-accepting chemotaxis
HZZ03_RS10350	ENOG4105CSH	Transporter
HZZ03_RS10355	ENOG4105CPW	cytochrome b561
HZZ03_RS10365	ENOG4105C26	Dehydrogenase
HZZ03_RS10370	ENOG4107DB1	DUF218 domain
HZZ03_RS10375	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
HZZ03_RS10400	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HZZ03_RS10410	ENOG4108UK5	Transposase
HZZ03_RS10415	ENOG4105CQ7	ATP-dependent helicase
HZZ03_RS10420	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HZZ03_RS10430	ENOG4105WXT	Conserved Protein
HZZ03_RS10435	ENOG410689M	(LipO)protein
HZZ03_RS10440	ENOG4107H52	Dicarboxylate transport
HZZ03_RS10445	ENOG4105C5I	Dehydrogenase
HZZ03_RS10450	ENOG41090X5	Heat shock protein hslJ
HZZ03_RS10455	ENOG4105IKK	cytoplasmic protein
HZZ03_RS10460	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
HZZ03_RS10475	ENOG4105C26	Dehydrogenase
HZZ03_RS10480	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
HZZ03_RS10490	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HZZ03_RS10500	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
HZZ03_RS10510	ENOG4107RX3	Mg2 transporter protein cora family protein
HZZ03_RS10520	ENOG410654E	Membrane
HZZ03_RS10535	ENOG4105BZU	Histidine kinase
HZZ03_RS10540	ENOG4105XF5	Escherichia coli IMT2125 genomic chromosome, IMT2125
HZZ03_RS10555	ENOG41066T8	Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during magnesium starvation (By similarity)
HZZ03_RS10565	ENOG4107QSI	ABC, transporter
HZZ03_RS10570	ENOG4105KXI	murein peptide amidase A
HZZ03_RS10575	ENOG4107S8C	mandelate racemase muconate lactonizing
HZZ03_RS10580	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HZZ03_RS10585	ENOG4108JU8	Transcriptional regulator
HZZ03_RS10590	ENOG4106K28	UPF0283 membrane protein
HZZ03_RS10595	ENOG4105CM6	amino acid regulated cytosolic protein
HZZ03_RS10600	ENOG4105FKQ	transcriptional regulator
HZZ03_RS10610	ENOG4107URF	beta-phospho-glucomutase
HZZ03_RS10615	ENOG4105C71	hydrolase family 65, central catalytic
HZZ03_RS10620	ENOG4105CK5	oxidoreductase
HZZ03_RS10640	ENOG4105Y9F	tail fiber protein
HZZ03_RS10645	ENOG4105Y0G	tail protein
HZZ03_RS10650	ENOG4108T86	baseplate J family protein
HZZ03_RS10690	ENOG4105TKZ	Tail Sheath
HZZ03_RS10740	ENOG4105CAR	Terminase, large subunit
HZZ03_RS10775	ENOG4105KUS	lysozyme
HZZ03_RS10780	ENOG4105QFS	Lysis protein S homolog from lambdoid prophage
HZZ03_RS10805	ENOG4108V2F	protein ybcN in lambdoid DLP12 prophage regi
HZZ03_RS10835	ENOG41087BU	transcriptional repressor DicA
HZZ03_RS10855	ENOG4107R08	Integrase
HZZ03_RS10860	ENOG4107TYA	transient receptor potential locus
HZZ03_RS10865	ENOG4107RRD	Dehydrogenase
HZZ03_RS10870	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
HZZ03_RS10875	ENOG4105HS6	binding-protein-dependent transport systems inner membrane Component
HZZ03_RS10880	ENOG4105WEM	extracellular solute-binding protein
HZZ03_RS10885	ENOG4107QW3	Sucrose phosphorylase
HZZ03_RS10890	ENOG4105NNG	Peripheral inner membrane phage-shock protein
HZZ03_RS10895	ENOG4105FM1	phage shock protein C
HZZ03_RS10900	ENOG4105YYT	phage shock protein B
HZZ03_RS10905	ENOG41087YS	Phage shock protein A
HZZ03_RS10910	ENOG4105E51	psp operon transcriptional activator
HZZ03_RS10915	ENOG4108J59	Extracellular solute-binding protein, family 5
HZZ03_RS10920	ENOG4108EKA	peptide transport system, permease
HZZ03_RS10925	ENOG4108EU3	peptide transport system, permease
HZZ03_RS10930	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
HZZ03_RS10935	ENOG4108JQ2	peptide transport system atp-binding protein
HZZ03_RS10940	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HZZ03_RS10945	ENOG4105Q4T	oxidoreductase
HZZ03_RS10950	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
HZZ03_RS10955	ENOG4105BZU	Histidine kinase
HZZ03_RS10960	ENOG4105E39	Enoyl-CoA hydratase
HZZ03_RS10965	ENOG4106BSC	UPF0509 protein
HZZ03_RS10975	ENOG4105F1A	Pyruvate formate-lyase
HZZ03_RS10985	ENOG4105N2W	Transcriptional regulator
HZZ03_RS10990	ENOG41061RM	osmotically inducible lipoprotein
HZZ03_RS10995	ENOG4108ZJT	translation initiation factor, Sui1
HZZ03_RS11005	ENOG4105CFV	Tetratricopeptide repeat protein
HZZ03_RS11010	ENOG4105Q4A	inner membrane protein yciS
HZZ03_RS11015	ENOG4105EYK	Phosphatidylglycerophosphatase B
HZZ03_RS11020	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
HZZ03_RS11025	ENOG4107QM5	aconitate hydratase
HZZ03_RS11035	ENOG4107R11	Transcriptional regulator
HZZ03_RS11040	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HZZ03_RS11045	ENOG4105RKX	Protein of unknown function (DUF2498)
HZZ03_RS11050	ENOG4105ERU	peptidase
HZZ03_RS11055	ENOG4105UBK	short-chain dehydrogenase reductase
HZZ03_RS11060	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
HZZ03_RS11070	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HZZ03_RS11075	ENOG4105DB7	PHP domain protein
HZZ03_RS11085	ENOG4105CRQ	synthase (Component I)
HZZ03_RS11090	ENOG4108EFP	Anthranilate synthase component II
HZZ03_RS11095	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HZZ03_RS11100	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HZZ03_RS11105	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HZZ03_RS11115	ENOG4105EIF	outer membrane protein W
HZZ03_RS11120	ENOG4105PI0	Ferredoxin
HZZ03_RS11125	ENOG4108S3I	UPF0259 membrane protein
HZZ03_RS11130	ENOG4107835	probably involved in intracellular septation (By similarity)
HZZ03_RS11135	ENOG4107RNH	Outer membrane receptor FepA
HZZ03_RS11140	ENOG4105NAU	thioesterase Superfamily protein
HZZ03_RS11145	ENOG410822N	TonB family
HZZ03_RS11150	ENOG4105K9H	YciI-like protein
HZZ03_RS11165	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HZZ03_RS11170	ENOG4108W5H	UPF0263 protein
HZZ03_RS11175	ENOG4105EYW	Ion transport protein
HZZ03_RS11180	ENOG4108JQ7	(ABC) transporter
HZZ03_RS11185	ENOG4105C3U	ABC transporter
HZZ03_RS11190	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HZZ03_RS11195	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HZZ03_RS11200	ENOG4107QSI	ABC, transporter
HZZ03_RS11205	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HZZ03_RS11210	ENOG4105C0A	alcohol dehydrogenase
HZZ03_RS11230	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HZZ03_RS11235	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HZZ03_RS11240	ENOG4105I93	response regulator
HZZ03_RS11250	ENOG4105CIY	formyltetrahydrofolate deformylase
HZZ03_RS11275	ENOG4105E1F	short-chain dehydrogenase reductase
HZZ03_RS11285	ENOG41076YT	nitrate reductase, gamma subunit
HZZ03_RS11290	ENOG4105R3A	Nitrate reductase
HZZ03_RS11295	ENOG4108IUE	nitrate reductase beta subunit
HZZ03_RS11300	ENOG4105CRU	nitrate reductase, alpha subunit
HZZ03_RS11305	ENOG4105DQQ	Major facilitator superfamily MFS_1
HZZ03_RS11310	ENOG4105BZU	Histidine kinase
HZZ03_RS11315	ENOG4105WH1	Two component transcriptional regulator luxr family
HZZ03_RS11320	ENOG4105ID0	Putative invasin
HZZ03_RS11335	ENOG4107QZF	nitrite reductase NADPH large subunit
HZZ03_RS11340	ENOG4105D7T	ABC transporter
HZZ03_RS11360	ENOG41090EX	DsrE family
HZZ03_RS11365	ENOG4105C8Q	Methyl-accepting chemotaxis
HZZ03_RS11375	ENOG4108NH8	Cation transport protein
HZZ03_RS11380	ENOG4105WS7	Cation transport regulator
HZZ03_RS11385	ENOG4105EWV	Sodium calcium exchanger membrane region
HZZ03_RS11390	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HZZ03_RS11395	ENOG41063JG	Transcriptional regulator
HZZ03_RS11400	ENOG4108YY7	Invasion gene expression up-regulator SirB
HZZ03_RS11405	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HZZ03_RS11410	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HZZ03_RS11415	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HZZ03_RS11425	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HZZ03_RS11430	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HZZ03_RS11435	ENOG4105CHH	sulfate transporter
HZZ03_RS11445	ENOG4105MGX	transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria
HZZ03_RS11450	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HZZ03_RS11455	ENOG4105C3G	gtp-binding protein
HZZ03_RS11460	ENOG4106RHG	Yeca family
HZZ03_RS11475	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
HZZ03_RS11485	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HZZ03_RS11495	ENOG4105E53	ec 3.2.1.28
HZZ03_RS11500	ENOG4105E0K	tonB-dependent siderophore receptor
HZZ03_RS11510	ENOG4108T7K	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity)
HZZ03_RS11515	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
HZZ03_RS11520	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
HZZ03_RS11535	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
HZZ03_RS11540	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HZZ03_RS11545	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HZZ03_RS11550	ENOG4105ED1	spovr family
HZZ03_RS11555	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
HZZ03_RS11560	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HZZ03_RS11565	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
HZZ03_RS11575	ENOG4108ZZ3	UPF0260 protein
HZZ03_RS11580	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
HZZ03_RS11585	ENOG4105VNG	YcgL domain-containing protein
HZZ03_RS11590	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
HZZ03_RS11595	ENOG4107QMS	site-determining protein
HZZ03_RS11600	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
HZZ03_RS11610	ENOG4105CEY	Amp-dependent synthetase and ligase
HZZ03_RS11615	ENOG4105Y4Z	Outer Membrane Lipoprotein
HZZ03_RS11620	ENOG41072GX	Peptidase M22 Glycoprotease
HZZ03_RS11625	ENOG4105DVT	helicase
HZZ03_RS11630	ENOG4105M4H	endoribonuclease L-psp
HZZ03_RS11665	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
HZZ03_RS11670	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HZZ03_RS11675	ENOG4105X5C	UPF0181 protein
HZZ03_RS11685	ENOG4105P8F	nudix hydrolase
HZZ03_RS11690	ENOG4105EJQ	L-serine dehydratase
HZZ03_RS11695	ENOG4107XTP	(EAL) domain protein
HZZ03_RS11700	ENOG4105EE5	Membrane protein terC
HZZ03_RS11705	ENOG4105DAS	pts system
HZZ03_RS11710	ENOG4105ETZ	PTS System
HZZ03_RS11715	ENOG4105F3R	pts system mannose fructose sorbose family iid
HZZ03_RS11720	ENOG4108NK4	UPF0266 membrane protein
HZZ03_RS11725	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
HZZ03_RS11730	ENOG4105DHI	Methyltransferase
HZZ03_RS11750	ENOG4105Q3Y	exported protein
HZZ03_RS11755	ENOG4106CCY	Protein MgrB homolog
HZZ03_RS11760	ENOG4105TIK	
HZZ03_RS11765	ENOG4105J4Q	Transcriptional regulator
HZZ03_RS11770	ENOG4105D0M	Protease HtpX homolog
HZZ03_RS11775	ENOG4105CN1	protease
HZZ03_RS11780	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
HZZ03_RS11785	ENOG4108ZGC	gaf domain protein
HZZ03_RS11790	ENOG4105H2K	paraquat-inducible protein a
HZZ03_RS11795	ENOG4105DY2	Paraquat-inducible protein b
HZZ03_RS11800	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HZZ03_RS11805	ENOG4105WT8	Protein of unknown function (DUF1480)
HZZ03_RS11810	ENOG4105UVW	uncharacterized protein yebW
HZZ03_RS11815	ENOG4108R1E	Serine threonine protein phosphatase 1
HZZ03_RS11830	ENOG4105NKT	exported protein
HZZ03_RS11835	ENOG4108PNC	copper resistance
HZZ03_RS11840	ENOG4105FXM	Copper resistance protein
HZZ03_RS11845	ENOG4105MPK	DNA polymerase III subunit theta
HZZ03_RS11850	ENOG4105UMD	exodeoxyribonuclease X
HZZ03_RS11855	ENOG4105CUG	Oligopeptidase b
HZZ03_RS11860	ENOG4108Q2J	Inner membrane protein YebE
HZZ03_RS11870	ENOG4105X2V	dna damage-inducible protein
HZZ03_RS11875	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
HZZ03_RS11880	ENOG4108UHU	Aldolase
HZZ03_RS11885	ENOG4105C01	Dihydroxy-acid dehydratase
HZZ03_RS11890	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HZZ03_RS11895	ENOG4106KNT	transcriptional regulator
HZZ03_RS11900	ENOG4105CA9	Pyruvate kinase
HZZ03_RS11905	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
HZZ03_RS11910	ENOG4105DR5	peptidase
HZZ03_RS11915	ENOG4105NXV	High-affinity zinc uptake system protein
HZZ03_RS11925	ENOG4105FAV	ABC, transporter
HZZ03_RS11930	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HZZ03_RS11935	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HZZ03_RS11940	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HZZ03_RS11945	ENOG4105CDY	transcriptional regulatory protein
HZZ03_RS11950	ENOG4108TIT	dATP pyrophosphohydrolase
HZZ03_RS11955	ENOG4105C9M	aspartyl-trna synthetase
HZZ03_RS11960	ENOG4105D3W	isochorismatase
HZZ03_RS11965	ENOG41081XQ	Conserved Protein
HZZ03_RS11970	ENOG4105WJG	Glutathione
HZZ03_RS11975	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
HZZ03_RS11980	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
HZZ03_RS11985	ENOG4109066	lysm domain bon superfamily protein
HZZ03_RS11990	ENOG4105QFC	Hsc56 co-chaperone of HscC
HZZ03_RS11995	ENOG4105F7F	Chaperone
HZZ03_RS12000	ENOG4106N3A	copper homeostasis protein cutc
HZZ03_RS12005	ENOG4105C87	Aminotransferase class I and II
HZZ03_RS12020	ENOG4106ZCM	YecM protein
HZZ03_RS12025	ENOG4105C75	arginyL-tRNA synthetase
HZZ03_RS12030	ENOG4108PNB	DNA-binding transcriptional regulator
HZZ03_RS12035	ENOG4105F5H	Glycosyl Hydrolase Family 88
HZZ03_RS12040	ENOG4105CT4	transporter
HZZ03_RS12045	ENOG4105IRD	Flagellar protein FlhE
HZZ03_RS12050	ENOG4105D7B	Flagellar biosynthesis protein flha
HZZ03_RS12055	ENOG4105D00	flagellar biosynthetic protein flhB
HZZ03_RS12060	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
HZZ03_RS12065	ENOG4108VYJ	response regulator receiver protein
HZZ03_RS12070	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HZZ03_RS12075	ENOG4105BZU	Histidine kinase
HZZ03_RS12080	ENOG4105C8Q	Methyl-accepting chemotaxis
HZZ03_RS12110	ENOG4108V3W	Chemotaxis protein, CheW
HZZ03_RS12115	ENOG4105CBS	Chea signal transduction histidine kinase
HZZ03_RS12120	ENOG4105ER2	Ompa motb domain protein
HZZ03_RS12125	ENOG4107RD7	Flagellar Motor Protein, MotA
HZZ03_RS12130	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
HZZ03_RS12135	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
HZZ03_RS12140	ENOG4108VA4	Universal stress protein
HZZ03_RS12145	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
HZZ03_RS12150	ENOG4108K4C	ec 3.1.3.12
HZZ03_RS12155	ENOG4105CNN	ABC, transporter
HZZ03_RS12165	ENOG4105DMK	Periplasmic binding protein LacI transcriptional regulator
HZZ03_RS12170	ENOG4105Q95	Cupin 2, conserved barrel domain protein
HZZ03_RS12175	ENOG4108UEC	Ferritin-like protein
HZZ03_RS12180	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
HZZ03_RS12195	ENOG4105N4N	Protein of unknown function (DUF2766)
HZZ03_RS12205	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HZZ03_RS12215	ENOG4105C8Q	Methyl-accepting chemotaxis
HZZ03_RS12225	ENOG41090A1	ferritin
HZZ03_RS12230	ENOG4105E0U	tyrosine-specific transport protein
HZZ03_RS12260	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HZZ03_RS12265	ENOG4105WH1	Two component transcriptional regulator luxr family
HZZ03_RS12270	ENOG4105XVG	cytoplasmic protein
HZZ03_RS12275	ENOG4105VJY	transcriptional regulator
HZZ03_RS12280	ENOG4105CDA	abc transporter atp-binding protein
HZZ03_RS12285	ENOG4105E5Q	amino acid AbC transporter
HZZ03_RS12295	ENOG4105EAB	amino acid AbC transporter
HZZ03_RS12300	ENOG4108M9K	flagella biosynthesis protein FliZ
HZZ03_RS12305	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HZZ03_RS12320	ENOG4105CEY	Amp-dependent synthetase and ligase
HZZ03_RS12330	ENOG4105CHR	reductase
HZZ03_RS12335	ENOG4105CHR	reductase
HZZ03_RS12375	ENOG4105MQ3	flagellar protein FliS
HZZ03_RS12380	ENOG4105YXP	it directly binds FlhC, thus inhibiting the binding of the FlhC FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus (By similarity)
HZZ03_RS12385	ENOG4108W9D	(LipO)protein
HZZ03_RS12390	ENOG41066VF	YeeE YedE family protein
HZZ03_RS12400	ENOG4108RAV	Conserved protein
HZZ03_RS12405	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HZZ03_RS12410	ENOG4105EMY	transcriptional regulator
HZZ03_RS12415	ENOG4105F27	Major Facilitator
HZZ03_RS12440	ENOG4108VBH	Uncharacterized protein conserved in bacteria (DUF2251)
HZZ03_RS12460	ENOG4108EU4	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HZZ03_RS12505	ENOG4105CAU	Arsenical resistance protein, ArsH
HZZ03_RS12525	ENOG4105W1Y	Transcriptional regulator
HZZ03_RS12545	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HZZ03_RS12560	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
HZZ03_RS12565	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HZZ03_RS12570	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HZZ03_RS12575	ENOG41090PJ	Flagellar assembly protein
HZZ03_RS12580	ENOG4108JIR	Flagellum-specific ATP synthase
HZZ03_RS12585	ENOG4105GSA	Flagellar export protein flij
HZZ03_RS12590	ENOG4105WF4	Flagellar hook-length control protein
HZZ03_RS12595	ENOG4107ZI8	flagellar basal body-associated protein flil
HZZ03_RS12600	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HZZ03_RS12605	ENOG4105DD5	Flagellar motor switch protein
HZZ03_RS12610	ENOG4105K0P	flagellar biosynthesis protein
HZZ03_RS12615	ENOG4105CN7	Flagellar biosynthetic protein FliP
HZZ03_RS12620	ENOG4105VS8	Flagellar biosynthetic protein fliq
HZZ03_RS12625	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
HZZ03_RS12630	ENOG4107TKS	colanic acid capsular biosynthesis activation protein A
HZZ03_RS12640	ENOG4105YX3	cellular response to acidity
HZZ03_RS12645	ENOG4108ZFX	Mannosyl-3-phosphoglycerate phosphatase
HZZ03_RS12655	ENOG4105VNZ	cytoplasmic protein
HZZ03_RS12660	ENOG4105CKW	Inner membrane protein yedI
HZZ03_RS12665	ENOG4105FDR	Membrane
HZZ03_RS12670	ENOG41090BB	DNA mismatch endonuclease (vsr)
HZZ03_RS12675	ENOG4105DVF	Cytosine-specific methyltransferase
HZZ03_RS12680	ENOG4105EST	Metal Dependent Phosphohydrolase
HZZ03_RS12685	ENOG4105FCK	Membrane
HZZ03_RS12690	ENOG4105Y50	Virulence Protein
HZZ03_RS12695	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
HZZ03_RS12705	ENOG4105HEI	LysR family (Transcriptional regulator
HZZ03_RS12720	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
HZZ03_RS12730	ENOG4105CSH	Transporter
HZZ03_RS12735	ENOG4107R11	Transcriptional regulator
HZZ03_RS12750	ENOG4108M8W	Monooxygenase
HZZ03_RS12755	ENOG4105BZU	Histidine kinase
HZZ03_RS12760	ENOG4105FYV	Amp nucleosidase
HZZ03_RS12785	ENOG4105CS6	Rhs element vgr protein
HZZ03_RS12790	ENOG4105UQX	Mate efflux family protein
HZZ03_RS12800	ENOG41090HJ	UPF0265 protein
HZZ03_RS12805	ENOG4105DR8	Membrane
HZZ03_RS12810	ENOG4108S5C	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity)
HZZ03_RS12815	ENOG4105DZ1	carboxypeptidase
HZZ03_RS12825	ENOG4105CJB	Exodeoxyribonuclease I
HZZ03_RS12830	ENOG4105CUB	amino acid
HZZ03_RS12840	ENOG4108JPW	Aminotransferase
HZZ03_RS12845	ENOG4108Z86	Glutamine amidotransferase
HZZ03_RS12850	ENOG4107SRH	Nad-dependent epimerase dehydratase
HZZ03_RS12860	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HZZ03_RS12865	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HZZ03_RS12870	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HZZ03_RS12875	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HZZ03_RS12880	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HZZ03_RS12885	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HZZ03_RS12890	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HZZ03_RS12900	ENOG4108KPN	Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12)
HZZ03_RS12905	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HZZ03_RS12925	ENOG4105K64	Glycosyl transferase, family 2
HZZ03_RS12930	ENOG4105EGZ	biosynthesis protein
HZZ03_RS12945	ENOG4105FFM	Resistance to gentamicin, tobramycin, and kanamycin. Tobramycin and kanamycin resistance is due to the ACC activity, specified by N-terminal region, and the gentamicin resistance is due to the APH activity encoded by the C-terminal region of the protein (By similarity)
HZZ03_RS12955	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HZZ03_RS12960	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HZZ03_RS12965	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HZZ03_RS12970	ENOG4105DMT	epimerase dehydratase
HZZ03_RS12975	ENOG4105G1A	colanic acid biosynthesis protein
HZZ03_RS12980	ENOG4107T8Q	Glycosyl transferase (Group 1
HZZ03_RS12985	ENOG4105C74	pyruvyl transferase
HZZ03_RS12990	ENOG4105PSV	Polysaccharide Biosynthesis Protein
HZZ03_RS12995	ENOG4105D3Q	Sugar transferase
HZZ03_RS13000	ENOG4107QKV	phosphomannomutase
HZZ03_RS13005	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
HZZ03_RS13010	ENOG4106CD9	glycosyl transferase group 1
HZZ03_RS13015	ENOG4105FGF	GDP-mannose mannosyl hydrolase
HZZ03_RS13020	ENOG4105C30	Nad-dependent epimerase dehydratase
HZZ03_RS13025	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
HZZ03_RS13030	ENOG4108Z90	colanic acid biosynthesis acetyltransferase wcaF
HZZ03_RS13035	ENOG4105ECJ	Glycosyl Transferase
HZZ03_RS13040	ENOG4108NYJ	Colanic acid
HZZ03_RS13045	ENOG4107RXY	Glycosyl transferase
HZZ03_RS13050	ENOG41068PY	Colanic acid biosynthesis acetyltransferase wcaB
HZZ03_RS13055	ENOG41090RK	glycosyl transferase
HZZ03_RS13060	ENOG4105D75	Capsular exopolysaccharide family
HZZ03_RS13065	ENOG4105KJF	protein tyrosine phosphatase
HZZ03_RS13070	ENOG4105DAY	polysaccharide export protein
HZZ03_RS13075	ENOG4105EE5	Membrane protein terC
HZZ03_RS13080	ENOG4108GAE	asmA family
HZZ03_RS13085	ENOG4105DHP	deoxycytidine triphosphate deaminase
HZZ03_RS13090	ENOG4105DBI	uridine monophosphokinase
HZZ03_RS13095	ENOG4105BZU	Histidine kinase
HZZ03_RS13100	ENOG4105D03	DNA-3-methyladenine glycosylase II
HZZ03_RS13105	ENOG4105R8A	Heat shock protein
HZZ03_RS13115	ENOG4105XUP	Phage derived protein Gp49-like (DUF891)
HZZ03_RS13125	ENOG4105BZS	acriflavin resistance protein
HZZ03_RS13130	ENOG4105BZS	acriflavin resistance protein
HZZ03_RS13135	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HZZ03_RS13140	ENOG4105EB3	Histidine kinase
HZZ03_RS13145	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HZZ03_RS13150	ENOG4105CFP	Peptidase U32
HZZ03_RS13155	ENOG4107TE5	Lipid kinase
HZZ03_RS13160	ENOG4105EIE	fructose-bisphosphate aldolase
HZZ03_RS13165	ENOG4105DWF	phosphomethylpyrimidine kinase
HZZ03_RS13170	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
HZZ03_RS13185	ENOG4108Z1S	Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly
HZZ03_RS13190	ENOG4105C5H	ABC transporter
HZZ03_RS13205	ENOG4105C8Q	Methyl-accepting chemotaxis
HZZ03_RS13210	ENOG4108NEV	two component transcriptional regulator, LytTR family
HZZ03_RS13215	ENOG4108HRK	Histidine kinase
HZZ03_RS13225	ENOG4105D1F	ATP-binding protein
HZZ03_RS13245	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HZZ03_RS13250	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HZZ03_RS13260	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HZZ03_RS13265	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HZZ03_RS13270	ENOG4108XDN	Transcriptional regulator
HZZ03_RS13280	ENOG4105WJV	Binding-protein-dependent transport systems, inner membrane component
HZZ03_RS13285	ENOG4108IJ8	ABC transporter
HZZ03_RS13290	ENOG4107T5X	Binding-protein-dependent transport systems, inner membrane component
HZZ03_RS13295	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
HZZ03_RS13300	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
HZZ03_RS13305	ENOG4105CXG	d-lactate dehydrogenase
HZZ03_RS13315	ENOG41061WM	D-Alanyl-D-Alanine
HZZ03_RS13320	ENOG41069YE	inner membrane protein yohC
HZZ03_RS13325	ENOG4105KHU	inner membrane protein YohD
HZZ03_RS13330	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
HZZ03_RS13350	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
HZZ03_RS13365	ENOG4105VAW	lrga family
HZZ03_RS13370	ENOG41067MG	lrgb family
HZZ03_RS13375	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
HZZ03_RS13380	ENOG4107GZ4	SanA protein
HZZ03_RS13385	ENOG4107SDZ	Galactoside transport system permease protein mglC
HZZ03_RS13390	ENOG4105C2J	ABC transporter
HZZ03_RS13395	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
HZZ03_RS13400	ENOG41060NJ	transcriptional regulator
HZZ03_RS13405	ENOG4105DHF	Membrane
HZZ03_RS13410	ENOG4105EUJ	GTP cyclohydrolase i
HZZ03_RS13415	ENOG4105CBP	Major Facilitator
HZZ03_RS13425	ENOG4108IQI	permease
HZZ03_RS13430	ENOG4105DUM	transcriptional regulator, lysR family
HZZ03_RS13435	ENOG4105HMI	Membrane
HZZ03_RS13440	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
HZZ03_RS13450	ENOG4105DM4	PTS System
HZZ03_RS13455	ENOG4105DE4	1-phosphofructokinase
HZZ03_RS13460	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
HZZ03_RS13465	ENOG4105S8Q	sugar efflux transporter
HZZ03_RS13470	ENOG4105KRS	Proteinase inhibitor
HZZ03_RS13480	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HZZ03_RS13485	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
HZZ03_RS13490	ENOG4105DEI	Mannitol dehydrogenase
HZZ03_RS13495	ENOG4105CKI	cobalamin synthesis protein
HZZ03_RS13500	ENOG41076MN	Phosphoesterase, PA-phosphatase related
HZZ03_RS13505	ENOG4107TT5	NLP P60 protein
HZZ03_RS13510	ENOG4105CXC	rtn protein
HZZ03_RS13515	ENOG4105E43	Extracellular solute-binding protein, family 5
HZZ03_RS13520	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
HZZ03_RS13525	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
HZZ03_RS13530	ENOG4108JQ5	ABC transporter
HZZ03_RS13535	ENOG4105HG6	
HZZ03_RS13545	ENOG4105C2C	drug resistance transporter, Bcr CflA
HZZ03_RS13550	ENOG4105I08	Pseudouridine synthase
HZZ03_RS13555	ENOG4105CFI	type iii restriction protein res subunit
HZZ03_RS13560	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HZZ03_RS13565	ENOG4106V8H	Nucleoid-associated protein
HZZ03_RS13570	ENOG4105PAN	UPF0352 protein
HZZ03_RS13575	ENOG4105E68	Sulfatase
HZZ03_RS13620	ENOG4108VCD	Chaperone
HZZ03_RS13630	ENOG4105CHH	sulfate transporter
HZZ03_RS13635	ENOG4105IBP	Cyclic peptide transporter
HZZ03_RS13640	ENOG4105CF1	Alkylated DNA repair protein
HZZ03_RS13645	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HZZ03_RS13650	ENOG4105CJ2	(LipO)protein
HZZ03_RS13655	ENOG4105FCK	Membrane
HZZ03_RS13660	ENOG4105E3G	Phosphotransfer intermediate protein in two-component regulatory system with RcsBC
HZZ03_RS13665	ENOG41068CG	regulatoR
HZZ03_RS13670	ENOG4105BZU	Histidine kinase
HZZ03_RS13675	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HZZ03_RS13680	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HZZ03_RS13685	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HZZ03_RS13690	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HZZ03_RS13695	ENOG4105XPH	Ferredoxin
HZZ03_RS13700	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
HZZ03_RS13705	ENOG4105CXY	transporter
HZZ03_RS13715	ENOG4108UII	YfaZ family
HZZ03_RS13720	ENOG4105DHQ	Histidine kinase
HZZ03_RS13745	ENOG4108R5S	membrane
HZZ03_RS13750	ENOG4105CEY	Amp-dependent synthetase and ligase
HZZ03_RS13760	ENOG4108IPT	Naphthoate synthase
HZZ03_RS13765	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
HZZ03_RS13770	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
HZZ03_RS13775	ENOG4105E4F	Isochorismate synthase
HZZ03_RS13780	ENOG4105TNS	Conserved Protein
HZZ03_RS13785	ENOG4107YB6	acetyltransferase, (GNAT) family
HZZ03_RS13790	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HZZ03_RS13795	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HZZ03_RS13800	ENOG4105C8S	subunit m
HZZ03_RS13805	ENOG4105D65	subunit l
HZZ03_RS13810	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HZZ03_RS13815	ENOG4107UFS	subunit j
HZZ03_RS13820	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HZZ03_RS13825	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HZZ03_RS13830	ENOG4108IEH	NADH dehydrogenase subunit g
HZZ03_RS13835	ENOG4107QIZ	NADH dehydrogenase
HZZ03_RS13840	ENOG4105GKE	subunit e
HZZ03_RS13845	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HZZ03_RS13850	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HZZ03_RS13855	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HZZ03_RS13860	ENOG4107NQ8	LysR family Transcriptional regulator
HZZ03_RS13865	ENOG4105CHM	Aminotransferase
HZZ03_RS13870	ENOG4105DK2	UPF0207 protein
HZZ03_RS13875	ENOG4107QWE	)-transporter
HZZ03_RS13880	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
HZZ03_RS13885	ENOG4105XWI	UPF0304 protein
HZZ03_RS13890	ENOG4105PQ6	UPF0208 membrane protein
HZZ03_RS13895	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HZZ03_RS13900	ENOG4105C6K	Malic enzyme
HZZ03_RS13905	ENOG4105WQ6	Membrane
HZZ03_RS13910	ENOG4105HFT	AraC family transcriptional regulator
HZZ03_RS13915	ENOG41082JN	Transcriptional regulator
HZZ03_RS13920	ENOG4105PTV	Nudix Hydrolase
HZZ03_RS13925	ENOG4108RE9	Phosphodiesterase
HZZ03_RS13930	ENOG4108SHQ	Glutathione S-transferase
HZZ03_RS13935	ENOG4105CYM	Glutathione S-transferase
HZZ03_RS13940	ENOG4105ECP	epimerase
HZZ03_RS13955	ENOG4108JEH	abc transporter atp-binding protein
HZZ03_RS13960	ENOG4106YG3	ABC transporter
HZZ03_RS13965	ENOG4105DSP	amino acid AbC transporter
HZZ03_RS13970	ENOG4105E89	ABC transporter
HZZ03_RS13975	ENOG4105E89	ABC transporter
HZZ03_RS13980	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HZZ03_RS13985	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HZZ03_RS13990	ENOG4105E96	Colicin v production protein
HZZ03_RS13995	ENOG4108S3P	Sporulation domain protein
HZZ03_RS14000	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HZZ03_RS14005	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HZZ03_RS14010	ENOG4105DQR	SNARE associated Golgi
HZZ03_RS14015	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HZZ03_RS14020	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HZZ03_RS14025	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
HZZ03_RS14030	ENOG4106WZ1	flagella biosynthesis regulator
HZZ03_RS14040	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HZZ03_RS14045	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HZZ03_RS14050	ENOG4105MH2	YfcL protein
HZZ03_RS14055	ENOG4108BPE	-transporting atpase
HZZ03_RS14060	ENOG4105EJ9	Membrane
HZZ03_RS14070	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HZZ03_RS14075	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
HZZ03_RS14085	ENOG4108BY2	phosphohistidine phosphatase
HZZ03_RS14090	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HZZ03_RS14095	ENOG4105CHU	acetyl-coa acetyltransferase
HZZ03_RS14100	ENOG4105KZW	UPF0381 protein
HZZ03_RS14105	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
HZZ03_RS14110	ENOG410903C	(LipO)protein
HZZ03_RS14115	ENOG4105KWW	Biogenesis protein
HZZ03_RS14120	ENOG4105KWW	Biogenesis protein
HZZ03_RS14130	ENOG4105DA4	cytochrome c-type biogenesis protein
HZZ03_RS14135	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
HZZ03_RS14140	ENOG4105X3C	heme exporter protein
HZZ03_RS14145	ENOG41060IM	Heme exporter protein
HZZ03_RS14150	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
HZZ03_RS14155	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
HZZ03_RS14160	ENOG4105S64	Formate nitrite transporter
HZZ03_RS14175	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HZZ03_RS14180	ENOG4105CHR	reductase
HZZ03_RS14185	ENOG4105C7K	acetolactate synthase
HZZ03_RS14200	ENOG4105D7N	magnesium and cobalt transport protein CorA
HZZ03_RS14215	ENOG4105CHM	Aminotransferase
HZZ03_RS14220	ENOG41072TH	Protein of unknown function (DUF1479)
HZZ03_RS14225	ENOG4108HRK	Histidine kinase
HZZ03_RS14230	ENOG4105DY9	regulatoR
HZZ03_RS14235	ENOG4105CHC	glucokinase (EC 2.7.1.2)
HZZ03_RS14240	ENOG4107RA9	decarboxylase
HZZ03_RS14245	ENOG4105CPC	Aldo Keto reductase
HZZ03_RS14250	ENOG4109076	Conserved Protein
HZZ03_RS14255	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
HZZ03_RS14260	ENOG4105D9N	nucleoside
HZZ03_RS14265	ENOG4108KMM	Diguanylate cyclase
HZZ03_RS14280	ENOG4105HZG	regulatoR
HZZ03_RS14290	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HZZ03_RS14320	ENOG4105VRT	cytoplasmic protein
HZZ03_RS14325	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HZZ03_RS14330	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
HZZ03_RS14335	ENOG4105EXN	Sulfate transport protein CysZ
HZZ03_RS14340	ENOG4105C6T	cysteine synthase
HZZ03_RS14350	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HZZ03_RS14355	ENOG4105C5Y	PTS System
HZZ03_RS14360	ENOG4105M0Y	
HZZ03_RS14365	ENOG4105C6T	cysteine synthase
HZZ03_RS14370	ENOG4108IJ6	ABC transporter
HZZ03_RS14375	ENOG4105ECW	sulfate abc transporter
HZZ03_RS14380	ENOG4108I5D	sulfate abc transporter
HZZ03_RS14385	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
HZZ03_RS14390	ENOG4105EZR	dyp-type peroxidase family protein
HZZ03_RS14395	ENOG4105E7K	(LipO)protein
HZZ03_RS14400	ENOG4105QZU	Inner membrane protein YfeZ
HZZ03_RS14405	ENOG4105H4F	exported protein
HZZ03_RS14410	ENOG4108R6G	acetyltransferase
HZZ03_RS14415	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
HZZ03_RS14420	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
HZZ03_RS14425	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
HZZ03_RS14430	ENOG4105CT5	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity)
HZZ03_RS14445	ENOG4105CNN	ABC, transporter
HZZ03_RS14450	ENOG4105C2J	ABC transporter
HZZ03_RS14455	ENOG4107SCQ	Iron-containing alcohol dehydrogenase
HZZ03_RS14475	ENOG4105VCD	cytoplasmic protein
HZZ03_RS14480	ENOG4105D22	carbon starvation protein
HZZ03_RS14485	ENOG4108TZA	Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity)
HZZ03_RS14490	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
HZZ03_RS14495	ENOG4105WQI	isochorismatase
HZZ03_RS14500	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
HZZ03_RS14505	ENOG4105E4F	Isochorismate synthase
HZZ03_RS14510	ENOG4105PEC	Iron-enterobactin transporter periplasmic binding protein
HZZ03_RS14515	ENOG4105E8G	Major facilitator Superfamily
HZZ03_RS14520	ENOG4105DQ5	transport system permease protein
HZZ03_RS14525	ENOG4105TVJ	transport system, permease
HZZ03_RS14530	ENOG4105E0A	ABC, transporter
HZZ03_RS14535	ENOG4105C6K	Malic enzyme
HZZ03_RS14545	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HZZ03_RS14565	ENOG4108PVD	exported protein
HZZ03_RS14570	ENOG4107VIJ	nudix hydrolase
HZZ03_RS14575	ENOG4105WH1	Two component transcriptional regulator luxr family
HZZ03_RS14580	ENOG4105BZS	acriflavin resistance protein
HZZ03_RS14595	ENOG4105KUZ	arsenate reductase
HZZ03_RS14600	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HZZ03_RS14605	ENOG4105XYK	UPF0370 protein
HZZ03_RS14610	ENOG4106KED	esterase YpfH
HZZ03_RS14615	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
HZZ03_RS14620	ENOG4105CGZ	zinc metallopeptidase
HZZ03_RS14625	ENOG4105C8V	SAICAR synthetase
HZZ03_RS14630	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HZZ03_RS14635	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HZZ03_RS14640	ENOG4105RH4	Glycine cleavage system transcriptional repressor
HZZ03_RS14645	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HZZ03_RS14650	ENOG4105C02	permease
HZZ03_RS14655	ENOG4105ERG	peptidase m48, ste24p
HZZ03_RS14660	ENOG4105K89	arsenate reductase
HZZ03_RS14665	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
HZZ03_RS14670	ENOG4105C2W	permease
HZZ03_RS14680	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HZZ03_RS14685	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HZZ03_RS14690	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HZZ03_RS14695	ENOG4105C9X	ppx gppa phosphatase
HZZ03_RS14700	ENOG4105BZU	Histidine kinase
HZZ03_RS14705	ENOG41062G3	Protein of unknown function (DUF2633)
HZZ03_RS14710	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HZZ03_RS14715	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HZZ03_RS14720	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HZZ03_RS14725	ENOG4105D4Y	metalloprotease
HZZ03_RS14735	ENOG4105VPD	cellular component movement
HZZ03_RS14740	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HZZ03_RS14745	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HZZ03_RS14750	ENOG4105N21	Membrane
HZZ03_RS14760	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HZZ03_RS14765	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
HZZ03_RS14770	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HZZ03_RS14775	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HZZ03_RS14780	ENOG4108JQB	penicillin-binding protein 1C
HZZ03_RS14785	ENOG4105DN3	alpha-2-macroglobulin domain protein
HZZ03_RS14800	ENOG4105KHC	sulfurtransferase
HZZ03_RS14805	ENOG4106KNT	transcriptional regulator
HZZ03_RS14820	ENOG4105YYA	enhanced serine sensitivity protein SseB
HZZ03_RS14825	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HZZ03_RS14830	ENOG4105WVQ	Fe-S assembly protein IscX
HZZ03_RS14835	ENOG4108ZIT	Ferredoxin, 2FE-2S
HZZ03_RS14840	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
HZZ03_RS14850	ENOG4108Z4V	iron-sulfur cluster assembly
HZZ03_RS14855	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
HZZ03_RS14860	ENOG4105C3J	Cysteine desulfurase
HZZ03_RS14865	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HZZ03_RS14870	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
HZZ03_RS14875	ENOG4105ECY	inositol monophosphatase
HZZ03_RS14880	ENOG4105D7X	high-affinity nickel-transporter
HZZ03_RS14885	ENOG41065CD	Exported protein
HZZ03_RS14890	ENOG4108MN2	Stationary phase inducible protein CsiE
HZZ03_RS14895	ENOG4105D8G	Major Facilitator superfamily
HZZ03_RS14905	ENOG4105VUF	Transcriptional regulator
HZZ03_RS14910	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HZZ03_RS14920	ENOG4108YZA	Nitrogen regulatory protein pii
HZZ03_RS14925	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HZZ03_RS14930	ENOG4108SKK	alpha helix protein
HZZ03_RS14935	ENOG4107WP9	Histidine kinase
HZZ03_RS14940	ENOG4108ETH	Formylglycinamide ribotide synthetase
HZZ03_RS14950	ENOG4108Z6B	deaminase
HZZ03_RS14955	ENOG4105HYY	HAD superfamily (Subfamily IF) hydrolase, YfhB
HZZ03_RS14965	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HZZ03_RS14970	ENOG4106G6Q	Transcriptional regulator
HZZ03_RS14975	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HZZ03_RS14980	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HZZ03_RS14990	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
HZZ03_RS14995	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HZZ03_RS15000	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HZZ03_RS15005	ENOG4105C3F	Signal peptidase i
HZZ03_RS15010	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HZZ03_RS15015	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
HZZ03_RS15035	ENOG4108IYU	L-aspartate oxidase
HZZ03_RS15040	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
HZZ03_RS15045	ENOG4105C1J	atp-dependent rna helicase
HZZ03_RS15050	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
HZZ03_RS15060	ENOG4105EIB	trna rrna methyltransferase
HZZ03_RS15065	ENOG4105K63	Thioredoxin
HZZ03_RS15070	ENOG4106IUH	DTW domain containing protein
HZZ03_RS15075	ENOG4105CD5	CoA-binding domain protein
HZZ03_RS15080	ENOG4105JIM	Phosphatidylserine synthase
HZZ03_RS15085	ENOG4105T42	(LipO)protein
HZZ03_RS15090	ENOG4105CSH	Transporter
HZZ03_RS15110	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
HZZ03_RS15140	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HZZ03_RS15145	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HZZ03_RS15150	ENOG4105C34	Pseudouridine synthase
HZZ03_RS15155	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HZZ03_RS15165	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
HZZ03_RS15170	ENOG4105CQC	Prephenate dehydratase
HZZ03_RS15180	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
HZZ03_RS15185	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HZZ03_RS15200	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HZZ03_RS15205	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HZZ03_RS15210	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HZZ03_RS15215	ENOG4105K5M	30s ribosomal protein S16
HZZ03_RS15220	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HZZ03_RS15225	ENOG4106KVJ	cytochrome C assembly protein
HZZ03_RS15230	ENOG4108JU6	CBS domain protein
HZZ03_RS15235	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HZZ03_RS15240	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HZZ03_RS15245	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HZZ03_RS15250	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HZZ03_RS15255	ENOG4105VDB	UPF0125 protein
HZZ03_RS15260	ENOG4108Z1B	Cyclase dehydrase
HZZ03_RS15265	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HZZ03_RS15275	ENOG4105BZ1	(ABC) transporter
HZZ03_RS15295	ENOG4105DZR	Type I site-specific deoxyribonuclease
HZZ03_RS15305	ENOG4105EKX	Restriction modification system DNA (Specificity
HZZ03_RS15310	ENOG4105CVR	type I restriction-modification system
HZZ03_RS15330	ENOG4105C0D	helicase
HZZ03_RS15355	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
HZZ03_RS15360	ENOG4105VPI	YqaE family transport protein
HZZ03_RS15375	ENOG4108RNS	Exports L-alanine (By similarity)
HZZ03_RS15380	ENOG4108WMJ	Protein of unknown function (DUF2002)
HZZ03_RS15385	ENOG4108ZQZ	Bacterial protein of unknown function (DUF883)
HZZ03_RS15390	ENOG4105WAZ	(Glutaredoxin-like protein) NrdH
HZZ03_RS15395	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
HZZ03_RS15400	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HZZ03_RS15405	ENOG4107R25	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HZZ03_RS15410	ENOG4108IJ7	Glycine betaine
HZZ03_RS15415	ENOG4108HQS	Glycine betaine
HZZ03_RS15420	ENOG4105GIJ	Glycine betaine
HZZ03_RS15430	ENOG4105NTK	Transcriptional repressor Mpra
HZZ03_RS15435	ENOG4105CW7	secretion protein, HlyD family
HZZ03_RS15440	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HZZ03_RS15445	ENOG4105BZU	Histidine kinase
HZZ03_RS15450	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
HZZ03_RS15455	ENOG4105D9M	gamma-glutamylcysteine synthetase
HZZ03_RS15460	ENOG4105W39	Membrane
HZZ03_RS15465	ENOG4107VXZ	Hydrolase
HZZ03_RS15495	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
HZZ03_RS15500	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HZZ03_RS15505	ENOG4105Y3E	Modulates RecA activity (By similarity)
HZZ03_RS15510	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HZZ03_RS15515	ENOG4107TH8	cina domain protein
HZZ03_RS15520	ENOG4105CVE	Lytic murein transglycosylase
HZZ03_RS15525	ENOG4105CDA	abc transporter atp-binding protein
HZZ03_RS15530	ENOG4105E5Q	amino acid AbC transporter
HZZ03_RS15535	ENOG4106PMH	Extracellular solute-binding protein family 3
HZZ03_RS15545	ENOG4105C8Q	Methyl-accepting chemotaxis
HZZ03_RS15555	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HZZ03_RS15560	ENOG4105KZM	cytoplasmic protein
HZZ03_RS15565	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HZZ03_RS15570	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HZZ03_RS15580	ENOG4105JQN	Transcriptional regulator
HZZ03_RS15600	ENOG4108K5P	(LipO)protein
HZZ03_RS15605	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HZZ03_RS15610	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HZZ03_RS15615	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
HZZ03_RS15620	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HZZ03_RS15625	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
HZZ03_RS15630	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HZZ03_RS15635	ENOG4105N0Z	inner membrane protein ygbE
HZZ03_RS15640	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
HZZ03_RS15645	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
HZZ03_RS15650	ENOG4105C11	sulfate adenylyltransferase), subunit 2
HZZ03_RS15655	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HZZ03_RS15660	ENOG4108MXK	alkaline phosphatase isozyme conversion
HZZ03_RS15665	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
HZZ03_RS15670	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HZZ03_RS15675	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
HZZ03_RS15680	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
HZZ03_RS15685	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HZZ03_RS15690	ENOG4105HA9	of methanol dehydrogenase type
HZZ03_RS15695	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
HZZ03_RS15700	ENOG4105CI1	PTS System
HZZ03_RS15705	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
HZZ03_RS15715	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HZZ03_RS15720	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HZZ03_RS15725	ENOG4105DXN	mazG family
HZZ03_RS15730	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HZZ03_RS15735	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HZZ03_RS15740	ENOG4105BZU	Histidine kinase
HZZ03_RS15745	ENOG4105QDK	Flavodoxin
HZZ03_RS15750	ENOG4105DR9	pseudouridine synthase
HZZ03_RS15755	ENOG4105WP7	tRNA pseudouridine synthase C
HZZ03_RS15760	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
HZZ03_RS15765	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HZZ03_RS15770	ENOG4105EWT	decarboxylase family
HZZ03_RS15775	ENOG4105C44	Serine transporter
HZZ03_RS15780	ENOG4105EJQ	L-serine dehydratase
HZZ03_RS15785	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
HZZ03_RS15790	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
HZZ03_RS15795	ENOG4105M08	Membrane
HZZ03_RS15800	ENOG4105ETT	transcriptional Regulator, LysR family
HZZ03_RS15805	ENOG4105M5B	(LipO)protein
HZZ03_RS15810	ENOG4105C9B	Cysteine desulfurase
HZZ03_RS15815	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HZZ03_RS15820	ENOG4105CUZ	uba thif-type nad fad binding protein
HZZ03_RS15825	ENOG4105CA3	membrane-bound lytic murein transglycosylase
HZZ03_RS15840	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HZZ03_RS15845	ENOG4107QZM	n-acetylglutamate synthase
HZZ03_RS15850	ENOG4107QYX	exodeoxyribonuclease v alpha
HZZ03_RS15855	ENOG4107QKA	exodeoxyribonuclease V beta
HZZ03_RS15860	ENOG4107QXK	peptidase
HZZ03_RS15865	ENOG4105DSY	exodeoxyribonuclease V, gamma
HZZ03_RS15870	ENOG4105RVB	Prepilin peptidase dependent protein c
HZZ03_RS15875	ENOG4105SEN	Protein of unknown function (DUF2509) 
HZZ03_RS15880	ENOG4105JCS	prepilin peptidase dependent protein
HZZ03_RS15885	ENOG4105IPU	prepilin peptidase dependent protein A
HZZ03_RS15890	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HZZ03_RS15895	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HZZ03_RS15900	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
HZZ03_RS15905	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HZZ03_RS15915	ENOG4105EE5	Membrane protein terC
HZZ03_RS15920	ENOG4105SUV	lipoprotein YgdR
HZZ03_RS15925	ENOG4105CPC	Aldo Keto reductase
HZZ03_RS15930	ENOG4107S74	Lysophospholipid transporter LplT
HZZ03_RS15935	ENOG4105CEY	Amp-dependent synthetase and ligase
HZZ03_RS15940	ENOG41060NJ	transcriptional regulator
HZZ03_RS15950	ENOG4107YCY	Transcriptional regulator
HZZ03_RS15960	ENOG4105CS2	ec 3.2.1.21
HZZ03_RS15965	ENOG4105CK1	PTS System
HZZ03_RS15970	ENOG4105DDV	Transcriptional regulator (LacI family
HZZ03_RS15980	ENOG4105RQF	LysR family Transcriptional regulator
HZZ03_RS15995	ENOG4108QY5	Ferric enterobactin transport protein
HZZ03_RS16000	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
HZZ03_RS16005	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
HZZ03_RS16020	ENOG4105CHR	reductase
HZZ03_RS16025	ENOG4105CAZ	oligogalacturonide lyase
HZZ03_RS16030	ENOG4108QGT	oligogalacturonate-specific porin
HZZ03_RS16035	ENOG4105CHU	acetyl-coa acetyltransferase
HZZ03_RS16040	ENOG4108PNB	DNA-binding transcriptional regulator
HZZ03_RS16045	ENOG410829K	Lysine exporter protein (Lyse ygga)
HZZ03_RS16055	ENOG4108K5P	(LipO)protein
HZZ03_RS16060	ENOG4105CRK	lysyL-tRNA synthetase
HZZ03_RS16070	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HZZ03_RS16075	ENOG4105T95	Thiol disulfide interChange protein
HZZ03_RS16080	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HZZ03_RS16085	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
HZZ03_RS16090	ENOG4108YDB	Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB
HZZ03_RS16095	ENOG4105Y75	tpr repeat protein
HZZ03_RS16100	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HZZ03_RS16105	ENOG4108UT2	hemolysin iii
HZZ03_RS16110	ENOG4105N5Z	UPF0267 protein
HZZ03_RS16115	ENOG4108Q3X	Transcriptional regulator
HZZ03_RS16120	ENOG4105CS2	ec 3.2.1.21
HZZ03_RS16125	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HZZ03_RS16130	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HZZ03_RS16135	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HZZ03_RS16140	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HZZ03_RS16145	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HZZ03_RS16150	ENOG4105D0A	hydroxylase
HZZ03_RS16155	ENOG4107RAQ	aminopeptidase
HZZ03_RS16160	ENOG4105E07	UPF0149 protein
HZZ03_RS16165	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
HZZ03_RS16175	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HZZ03_RS16180	ENOG4108JQ1	Dehydrogenase
HZZ03_RS16185	ENOG4105E66	phosphoriboisomerase A
HZZ03_RS16190	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
HZZ03_RS16195	ENOG4105MPN	Membrane
HZZ03_RS16205	ENOG4105D64	Mechanosensitive ion channel
HZZ03_RS16210	ENOG4105D2N	Aldolase
HZZ03_RS16215	ENOG4105BZA	Phosphoglycerate kinase
HZZ03_RS16220	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HZZ03_RS16225	ENOG41065RQ	ADP-ribosylation crystallin J1
HZZ03_RS16230	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HZZ03_RS16235	ENOG4108K0D	peptidase, M48
HZZ03_RS16240	ENOG4105CYW	agmatinase
HZZ03_RS16245	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
HZZ03_RS16260	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HZZ03_RS16265	ENOG4107QNK	)-transporter
HZZ03_RS16270	ENOG4105GPY	SprT protein
HZZ03_RS16275	ENOG4105RWS	endonuclease I
HZZ03_RS16280	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HZZ03_RS16285	ENOG4105D7Z	glutathione synthase
HZZ03_RS16290	ENOG4108UJU	UPF0301 protein
HZZ03_RS16295	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HZZ03_RS16315	ENOG4105DFA	alanine racemase domain protein
HZZ03_RS16320	ENOG4108VIA	integral membrane protein
HZZ03_RS16325	ENOG4105VZ9	UPF0235 protein
HZZ03_RS16330	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HZZ03_RS16335	ENOG4105CSA	Coproporphyrinogen iii oxidase
HZZ03_RS16340	ENOG4107TZ2	Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity)
HZZ03_RS16345	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
HZZ03_RS16350	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HZZ03_RS16355	ENOG4105NF4	modulator of drug activity
HZZ03_RS16360	ENOG4105VRH	Antibiotic biosynthesis monooxygenase
HZZ03_RS16365	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
HZZ03_RS16370	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HZZ03_RS16375	ENOG4105IPS	esterase
HZZ03_RS16380	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HZZ03_RS16385	ENOG4108SX3	cytoplasmic protein
HZZ03_RS16390	ENOG41087AY	ADP-Ribose pyrophosphatase
HZZ03_RS16395	ENOG4105DFG	type I secretion outer membrane protein
HZZ03_RS16400	ENOG4105F1G	UPF0441 protein
HZZ03_RS16405	ENOG4106032	Glutathionylspermidine synthase
HZZ03_RS16410	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
HZZ03_RS16420	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HZZ03_RS16425	ENOG4105W0Z	cytoplasmic protein
HZZ03_RS16430	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HZZ03_RS16435	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HZZ03_RS16440	ENOG4105I7R	Adenylate cyclase
HZZ03_RS16445	ENOG4106MWK	domain protein
HZZ03_RS16450	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HZZ03_RS16455	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HZZ03_RS16460	ENOG4107ZVW	dihydroneopterin aldolase
HZZ03_RS16465	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HZZ03_RS16470	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HZZ03_RS16480	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HZZ03_RS16485	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HZZ03_RS16495	ENOG4108VCA	G U mismatch-specific DNA glycosylase
HZZ03_RS16515	ENOG4108UUE	Transcriptional regulator
HZZ03_RS16520	ENOG4108UK3	Polyprenyl synthetase
HZZ03_RS16525	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
HZZ03_RS16530	ENOG41087PP	glycosyltransferase MGT family
HZZ03_RS16540	ENOG4105EWK	phytoene
HZZ03_RS16545	ENOG4105FE1	phytoene synthase
HZZ03_RS16550	ENOG4105IJY	hydroxylase
HZZ03_RS16555	ENOG4105C8Q	Methyl-accepting chemotaxis
HZZ03_RS16560	ENOG4105D22	carbon starvation protein
HZZ03_RS16565	ENOG4105VCD	cytoplasmic protein
HZZ03_RS16570	ENOG4105CKI	cobalamin synthesis protein
HZZ03_RS16590	ENOG4105K33	Periplasmic Protein
HZZ03_RS16595	ENOG41090ED	Protein with unknown function (DUF469)
HZZ03_RS16600	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HZZ03_RS16605	ENOG4105CEN	a g-specific adenine glycosylase
HZZ03_RS16610	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
HZZ03_RS16615	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
HZZ03_RS16620	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
HZZ03_RS16630	ENOG4105CHY	citrate lyase, alpha
HZZ03_RS16635	ENOG4105CI0	Citrate lyase
HZZ03_RS16640	ENOG4105XGS	Covalent carrier of the coenzyme of citrate lyase (By similarity)
HZZ03_RS16645	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
HZZ03_RS16650	ENOG4105ERH	Fumarylacetoacetate hydrolase
HZZ03_RS16655	ENOG4105D2K	citrate carrier protein
HZZ03_RS16660	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
HZZ03_RS16665	ENOG4106YYS	transcriptional regulatory protein
HZZ03_RS16670	ENOG4105CXN	decarboxylase
HZZ03_RS16675	ENOG4108UQV	Membrane
HZZ03_RS16700	ENOG4108YGG	dna repair protein
HZZ03_RS16725	ENOG4105CVR	type I restriction-modification system
HZZ03_RS16730	ENOG4105EDV	vault protein
HZZ03_RS16735	ENOG41081SK	signal peptide protein
HZZ03_RS16740	ENOG4107S52	alpha-2-macroglobulin domain protein
HZZ03_RS16745	ENOG4108QJJ	Protein of unknown function (DUF1175)
HZZ03_RS16750	ENOG4107FKF	Uncharacterized protein conserved in bacteria (DUF2138)
HZZ03_RS16765	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HZZ03_RS16805	ENOG4108R5S	membrane
HZZ03_RS16810	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ03_RS16820	ENOG4105CK1	PTS System
HZZ03_RS16825	ENOG4105VCP	PTS System
HZZ03_RS16830	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
HZZ03_RS16835	ENOG4105D64	Mechanosensitive ion channel
HZZ03_RS16840	ENOG4108TEB	UPF0114 protein
HZZ03_RS16860	ENOG4107EDW	L-fucose operon activator
HZZ03_RS16865	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HZZ03_RS16870	ENOG4108ZZF	transport protein (ExbD)
HZZ03_RS16875	ENOG4105CWK	Biopolymer transport protein, ExbB
HZZ03_RS16880	ENOG4105C28	cystathionine
HZZ03_RS16885	ENOG4108K81	inner membrane protein YghB
HZZ03_RS16890	ENOG4105CF7	AraC family transcriptional regulator
HZZ03_RS16895	ENOG4108I6A	alcohol dehydrogenase
HZZ03_RS16900	ENOG4105CV8	reductase
HZZ03_RS16905	ENOG4105ZKC	Conserved Protein
HZZ03_RS16920	ENOG4105PF9	Transcriptional regulator
HZZ03_RS16925	ENOG4105D4X	repressor
HZZ03_RS16930	ENOG4105C5Y	PTS System
HZZ03_RS16935	ENOG4105CG3	alpha amylase, catalytic region
HZZ03_RS16940	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
HZZ03_RS16945	ENOG410810E	transcriptional regulator, lysR family
HZZ03_RS16950	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
HZZ03_RS16955	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
HZZ03_RS16960	ENOG4105K4U	addiction module toxin, RelE StbE family
HZZ03_RS16970	ENOG4105EMD	TRANSCRIPTIONal
HZZ03_RS16985	ENOG41069H0	dihydroorotase EC 3.5.2.3
HZZ03_RS17020	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
HZZ03_RS17025	ENOG4105N42	UPF0307 protein
HZZ03_RS17035	ENOG4105DFU	Cell wall formation (By similarity)
HZZ03_RS17040	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HZZ03_RS17045	ENOG4105C8Q	Methyl-accepting chemotaxis
HZZ03_RS17050	ENOG41062B0	ABC transporter, permease
HZZ03_RS17055	ENOG4107R9N	ABC transporter
HZZ03_RS17060	ENOG4105C2J	ABC transporter
HZZ03_RS17065	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
HZZ03_RS17070	ENOG4105F0N	pyrophosphate phospho-hydrolase
HZZ03_RS17075	ENOG4105C8Q	Methyl-accepting chemotaxis
HZZ03_RS17080	ENOG4108ZHD	aig2 family
HZZ03_RS17085	ENOG4105MA0	exported protein
HZZ03_RS17095	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HZZ03_RS17105	ENOG4105C37	(CBS) domain
HZZ03_RS17110	ENOG41061GZ	Protein of unknown function (DUF1107)
HZZ03_RS17115	ENOG4108UUE	Transcriptional regulator
HZZ03_RS17120	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HZZ03_RS17125	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
HZZ03_RS17130	ENOG4105KVH	Transcriptional regulator
HZZ03_RS17135	ENOG4105ECR	NmrA family
HZZ03_RS17145	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HZZ03_RS17155	ENOG4105DXC	membrane
HZZ03_RS17160	ENOG4105C8Q	Methyl-accepting chemotaxis
HZZ03_RS17165	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
HZZ03_RS17170	ENOG4105C85	amino acid
HZZ03_RS17175	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HZZ03_RS17180	ENOG4105FHY	Opacity-associated protein A
HZZ03_RS17185	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HZZ03_RS17190	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HZZ03_RS17195	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
HZZ03_RS17200	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HZZ03_RS17205	ENOG4108MXZ	Esterase
HZZ03_RS17210	ENOG4105WSB	biofilm stress and motility protein A
HZZ03_RS17215	ENOG4105S17	UPF0379 protein yjfN
HZZ03_RS17220	ENOG4105C8Q	Methyl-accepting chemotaxis
HZZ03_RS17225	ENOG4105CSU	acyl-Coa dehydrogenase
HZZ03_RS17230	ENOG4106032	Glutathionylspermidine synthase
HZZ03_RS17235	ENOG4108KXT	Conserved Protein
HZZ03_RS17240	ENOG4105Z6B	inner membrane protein yjfl
HZZ03_RS17245	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HZZ03_RS17250	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HZZ03_RS17260	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HZZ03_RS17270	ENOG4105EPW	hflc protein
HZZ03_RS17275	ENOG4107QJR	hflk protein
HZZ03_RS17280	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HZZ03_RS17290	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HZZ03_RS17295	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HZZ03_RS17300	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HZZ03_RS17305	ENOG4105K8N	protein family UPF0079, ATPase
HZZ03_RS17310	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HZZ03_RS17315	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HZZ03_RS17345	ENOG4105DJ4	phosphatidylserine decarboxylase
HZZ03_RS17350	ENOG4105EGS	Mechanosensitive ion channel
HZZ03_RS17360	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HZZ03_RS17365	ENOG4105E33	succinate dehydrogenase
HZZ03_RS17375	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
HZZ03_RS17380	ENOG4105QNF	Outer membrane lipoprotein
HZZ03_RS17395	ENOG4106BSU	Entericidin B
HZZ03_RS17405	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HZZ03_RS17410	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
HZZ03_RS17415	ENOG4108ZVF	(LipO)protein
HZZ03_RS17420	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HZZ03_RS17425	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HZZ03_RS17430	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
HZZ03_RS17435	ENOG4108IJ0	Aspartate ammonia-lyase
HZZ03_RS17440	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
HZZ03_RS17445	ENOG4105VF7	tolerance protein
HZZ03_RS17450	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HZZ03_RS17455	ENOG4108SIC	Transcriptional regulator
HZZ03_RS17480	ENOG4108YGG	dna repair protein
HZZ03_RS17505	ENOG4105CVR	type I restriction-modification system
HZZ03_RS17555	ENOG4105D7X	high-affinity nickel-transporter
HZZ03_RS17560	ENOG4105CYM	Glutathione S-transferase
HZZ03_RS17565	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
HZZ03_RS17570	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
HZZ03_RS17575	ENOG4108YIV	
HZZ03_RS17580	ENOG4108F5E	vimentin
HZZ03_RS17585	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HZZ03_RS17590	ENOG4105KZ6	phosphonate C-P lyase system protein PhnH
HZZ03_RS17605	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HZZ03_RS17620	ENOG4105CK2	sodium dicarboxylate symporter
HZZ03_RS17625	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HZZ03_RS17630	ENOG41062QD	Membrane
HZZ03_RS17635	ENOG4107QN1	sodium solute
HZZ03_RS17640	ENOG4105DDC	Oxidoreductase domain protein
HZZ03_RS17645	ENOG4105EEQ	Na H antiporter
HZZ03_RS17650	ENOG4105C7N	Xanthine uracil vitamin C permease
HZZ03_RS17655	ENOG4108RXX	maleylacetoacetate isomerase
HZZ03_RS17660	ENOG4108Z4X	TRANSCRIPTIONal
HZZ03_RS17665	ENOG4108W3Q	Transcriptional regulator
HZZ03_RS17670	ENOG4108M8H	domain protein
HZZ03_RS17675	ENOG4105PMV	Membrane
HZZ03_RS17715	ENOG4108FPN	Integrase
HZZ03_RS17720	ENOG4108UUM	single-stranded DNA-binding protein
HZZ03_RS17725	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HZZ03_RS17740	ENOG4105MSB	protein, conserved in bacteria
HZZ03_RS17745	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
HZZ03_RS17750	ENOG4105D5K	Hemolysin activator protein
HZZ03_RS17755	ENOG4105CGF	Aromatic amino acid aminotransferase
HZZ03_RS17760	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HZZ03_RS17765	ENOG4105CDU	Replicative dna helicase
HZZ03_RS17770	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HZZ03_RS17775	ENOG4105P4Z	Phage shock protein G
HZZ03_RS17780	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HZZ03_RS17795	ENOG4105MYN	Zinc uptake regulation protein
HZZ03_RS17800	ENOG4105VDW	Csbd family
HZZ03_RS17805	ENOG4107R73	Mate efflux family protein
HZZ03_RS17810	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HZZ03_RS17815	ENOG41080IJ	Diacylglycerol kinase
HZZ03_RS17825	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HZZ03_RS17830	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
HZZ03_RS17835	ENOG4107W52	maltose operon periplasmic protein
HZZ03_RS17840	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
HZZ03_RS17845	ENOG4108IJ9	(ABC) transporter
HZZ03_RS17850	ENOG4107FKK	extracellular solute-binding protein family 1
HZZ03_RS17855	ENOG4105D56	permease protein
HZZ03_RS17860	ENOG4105EG2	ABC transporter, permease
HZZ03_RS17875	ENOG4105E3R	(LipO)protein
HZZ03_RS17880	ENOG4108Q9C	Periplasmic Protein
HZZ03_RS17885	ENOG4108MDC	(LipO)protein
HZZ03_RS17895	ENOG4107QP8	phosphohexose isomerase
HZZ03_RS17900	ENOG4105CFH	Aspartokinase
HZZ03_RS17905	ENOG410756H	nucleotidyltransferase
HZZ03_RS17910	ENOG4105E0Y	RtcB Protein
HZZ03_RS17925	ENOG4105CYB	regulatoR
HZZ03_RS17930	ENOG4105C09	Bile acid
HZZ03_RS17935	ENOG4108ZR5	Conserved Protein
HZZ03_RS17940	ENOG4105EAM	Na Pi-cotransporter
HZZ03_RS17945	ENOG4105C3R	Methionine synthase
HZZ03_RS17950	ENOG41069M3	Transcriptional regulator
HZZ03_RS17955	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
HZZ03_RS17960	ENOG4108I9X	Isocitrate lyase
HZZ03_RS17965	ENOG4107QP3	malate synthase g
HZZ03_RS17970	ENOG4105CVG	Homoserine O-transsuccinylase
HZZ03_RS18000	ENOG4108Z0R	Transferase
HZZ03_RS18005	ENOG4105SG3	Protein of unknown function (DUF1488)
HZZ03_RS18010	ENOG4105E2X	shikimate dehydrogenase
HZZ03_RS18015	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HZZ03_RS18020	ENOG4108WI1	Dna topoisomerase
HZZ03_RS18030	ENOG4105C79	DNA protecting protein DprA
HZZ03_RS18035	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HZZ03_RS18040	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HZZ03_RS18045	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HZZ03_RS18050	ENOG4105C1A	potassium transporter peripheral membrane
HZZ03_RS18055	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HZZ03_RS18060	ENOG4105VCN	Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system
HZZ03_RS18065	ENOG4105W1Y	Transcriptional regulator
HZZ03_RS18070	ENOG4105VTS	DnaJ-like, subfamily C
HZZ03_RS18075	ENOG4108ZT0	50S ribosomal protein l17
HZZ03_RS18080	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HZZ03_RS18085	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HZZ03_RS18090	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HZZ03_RS18100	ENOG41067V7	50S ribosomal protein L36
HZZ03_RS18105	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HZZ03_RS18110	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HZZ03_RS18115	ENOG4105VPB	50S ribosomal protein L30
HZZ03_RS18120	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HZZ03_RS18125	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HZZ03_RS18130	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HZZ03_RS18135	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HZZ03_RS18140	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HZZ03_RS18145	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HZZ03_RS18150	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HZZ03_RS18155	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HZZ03_RS18165	ENOG41083MP	50s ribosomal protein l29
HZZ03_RS18170	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HZZ03_RS18175	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HZZ03_RS18185	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HZZ03_RS18205	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HZZ03_RS18220	ENOG4108UQY	Iron-storage protein
HZZ03_RS18225	ENOG4105W53	bacterioferritin-associated ferredoxin
HZZ03_RS18230	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HZZ03_RS18235	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HZZ03_RS18240	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HZZ03_RS18250	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
HZZ03_RS18255	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
HZZ03_RS18260	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
HZZ03_RS18265	ENOG4105WWK	YheO domain protein
HZZ03_RS18270	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HZZ03_RS18275	ENOG4105VRX	Protein slyX homolog
HZZ03_RS18280	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HZZ03_RS18285	ENOG4105VKU	nucleicacid-binding protein
HZZ03_RS18290	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HZZ03_RS18295	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
HZZ03_RS18300	ENOG4105C5H	ABC transporter
HZZ03_RS18305	ENOG4105CDW	Resistance protein
HZZ03_RS18320	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HZZ03_RS18330	ENOG4105DNZ	Alpha Beta Hydrolase
HZZ03_RS18335	ENOG4105YP7	UPF0270 protein
HZZ03_RS18340	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
HZZ03_RS18345	ENOG4108UKZ	OsmC family
HZZ03_RS18350	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
HZZ03_RS18355	ENOG410613R	integral membrane protein, YccS YhfK family
HZZ03_RS18360	ENOG4105C8Y	Acetylornithine aminotransferase
HZZ03_RS18370	ENOG4105MZU	cell filamentation protein
HZZ03_RS18380	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HZZ03_RS18385	ENOG4106DTQ	Protein TsgA homolog
HZZ03_RS18390	ENOG4107QZF	nitrite reductase NADPH large subunit
HZZ03_RS18395	ENOG4105WZK	nitrite reductase NADPH small subunit
HZZ03_RS18400	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HZZ03_RS18405	ENOG4107QHQ	amino acid
HZZ03_RS18410	ENOG4107R1S	catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine
HZZ03_RS18415	ENOG4107Y0V	Not clear, may be involved in an isomerization step
HZZ03_RS18420	ENOG4108KPW	sugar kinase
HZZ03_RS18425	ENOG4105FDP	GntR family transcriptional regulator
HZZ03_RS18430	ENOG4105VYH	
HZZ03_RS18435	ENOG4105C31	Tryptophanyl-tRNA synthetase
HZZ03_RS18445	ENOG4105DJV	ribulose-phosphate 3-epimerase
HZZ03_RS18450	ENOG4105DFE	Dna adenine methylase
HZZ03_RS18455	ENOG4105EGB	membrane protein DamX
HZZ03_RS18460	ENOG4105D49	3-dehydroquinate synthase
HZZ03_RS18470	ENOG4105E4G	Type IV pilus
HZZ03_RS18490	ENOG4108U1Q	Pilus assembly protein
HZZ03_RS18495	ENOG4108JQC	penicillin-binding protein 1A
HZZ03_RS18500	ENOG4107RK2	ADP-ribose diphosphatase NudE
HZZ03_RS18505	ENOG4105DQY	intracellular growth attenuator
HZZ03_RS18510	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
HZZ03_RS18515	ENOG4105VEJ	Heat shock protein
HZZ03_RS18520	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HZZ03_RS18525	ENOG4108MAJ	Membrane
HZZ03_RS18530	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
HZZ03_RS18535	ENOG4105E0F	Histidine kinase
HZZ03_RS18545	ENOG4108RRZ	Transcription elongation factor GreB
HZZ03_RS18550	ENOG4105BZM	domain protein
HZZ03_RS18555	ENOG4105XFK	Ferrous iron transport protein A
HZZ03_RS18560	ENOG4105CE1	Ferrous iron transport protein b
HZZ03_RS18565	ENOG41060N5	May function as a transcriptional regulator that controls feoABC expression (By similarity)
HZZ03_RS18575	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HZZ03_RS18580	ENOG4105MJ2	Competence protein
HZZ03_RS18585	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
HZZ03_RS18595	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
HZZ03_RS18600	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
HZZ03_RS18605	ENOG41061ZR	Transcriptional regulator
HZZ03_RS18610	ENOG4105E98	transcriptional regulator DeoR family
HZZ03_RS18615	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
HZZ03_RS18620	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
HZZ03_RS18625	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HZZ03_RS18640	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
HZZ03_RS18645	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HZZ03_RS18650	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
HZZ03_RS18655	ENOG4108ESZ	Glycogen debranching enzyme
HZZ03_RS18665	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HZZ03_RS18670	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
HZZ03_RS18685	ENOG4105C6Z	Gluconate
HZZ03_RS18690	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HZZ03_RS18695	ENOG4105DIQ	Transcriptional regulator
HZZ03_RS18700	ENOG4105C2I	pirin domain protein
HZZ03_RS18705	ENOG4105D9R	oxidoreductase
HZZ03_RS18710	ENOG4105WCN	acetyltransferase
HZZ03_RS18715	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HZZ03_RS18720	ENOG4105WC8	Conserved Protein
HZZ03_RS18725	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
HZZ03_RS18740	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
HZZ03_RS18745	ENOG4105BZ7	extracellular solute-binding protein family 1
HZZ03_RS18755	ENOG41060M8	Pfam:PhdYeFM
HZZ03_RS18760	ENOG4108IV0	ABC, transporter
HZZ03_RS18765	ENOG4105C0Z	ABC transporter
HZZ03_RS18770	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HZZ03_RS18775	ENOG4105C32	Amino acid ABC transporter (Permease)
HZZ03_RS18780	ENOG4105CP9	extracellular ligand-binding receptor
HZZ03_RS18785	ENOG4105U59	-acetyltransferase
HZZ03_RS18790	ENOG4105CP9	extracellular ligand-binding receptor
HZZ03_RS18800	ENOG4108JPW	Aminotransferase
HZZ03_RS18810	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HZZ03_RS18815	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
HZZ03_RS18820	ENOG4105CAK	Cell division ATP-binding protein ftsE
HZZ03_RS18825	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HZZ03_RS18830	ENOG4106H78	methyltransferase
HZZ03_RS18835	ENOG4105MG3	Membrane
HZZ03_RS18845	ENOG4107FS9	Membrane
HZZ03_RS18855	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HZZ03_RS18865	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HZZ03_RS18870	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
HZZ03_RS18875	ENOG4105EX9	Membrane
HZZ03_RS18880	ENOG4108W1V	Lipoprotein
HZZ03_RS18885	ENOG4105F9N	Major Facilitator Superfamily
HZZ03_RS18890	ENOG4105DSF	transport protein
HZZ03_RS18895	ENOG4107TT5	NLP P60 protein
HZZ03_RS18900	ENOG4105CFQ	glutamine synthetase
HZZ03_RS18905	ENOG4105CBX	hi0933 family
HZZ03_RS18910	ENOG4105CJ3	phosphate transporter
HZZ03_RS18915	ENOG4108V6B	universal stress protein B
HZZ03_RS18920	ENOG4108M6U	Universal stress protein A
HZZ03_RS18925	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
HZZ03_RS18930	ENOG4105DGW	oligopeptidase A
HZZ03_RS18935	ENOG4105D6S	protein involved in catabolism of external DNA
HZZ03_RS18940	ENOG4105DC8	reductase
HZZ03_RS18960	ENOG4108YDI	single-species biofilm formation on inanimate substrate
HZZ03_RS18965	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
HZZ03_RS18970	ENOG4105CBN	LysR family transcriptional regulator
HZZ03_RS18975	ENOG4107H3J	ribonuclease
HZZ03_RS18980	ENOG4105CSH	Transporter
HZZ03_RS18985	ENOG41066T0	asmA family
HZZ03_RS18990	ENOG4105CMB	EAL domain-containing protein
HZZ03_RS19000	ENOG4105CS0	peptidase
HZZ03_RS19005	ENOG4105CK2	sodium dicarboxylate symporter
HZZ03_RS19010	ENOG4105BZU	Histidine kinase
HZZ03_RS19015	ENOG4105EJG	cellulose synthase
HZZ03_RS19020	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
HZZ03_RS19025	ENOG4107EEX	Cellulose synthase regulator protein
HZZ03_RS19030	ENOG4107QZ7	Cellulose synthase catalytic subunit
HZZ03_RS19035	ENOG4105UTS	cellulose synthase operon protein YhjQ
HZZ03_RS19040	ENOG410661M	cytoplasmic protein
HZZ03_RS19050	ENOG410675P	Celllulose biosynthesis operon protein BcsF YhjT
HZZ03_RS19055	ENOG4105D1V	cellulose synthase operon protein YhjU
HZZ03_RS19060	ENOG4108JQ7	(ABC) transporter
HZZ03_RS19065	ENOG4105C3U	ABC transporter
HZZ03_RS19070	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HZZ03_RS19075	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HZZ03_RS19080	ENOG4105DEF	Extracellular solute-binding protein, family 5
HZZ03_RS19100	ENOG4105DIJ	Phosphoethanolamine transferase
HZZ03_RS19105	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HZZ03_RS19110	ENOG4105FCD	Major Facilitator
HZZ03_RS19115	ENOG4105EAX	Putative lipase
HZZ03_RS19120	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HZZ03_RS19130	ENOG4107QY8	reductase
HZZ03_RS19135	ENOG4108ZG0	Ompa motb domain protein
HZZ03_RS19140	ENOG4108MEK	Metal-binding protein YodA
HZZ03_RS19145	ENOG4108M60	Transcriptional regulator
HZZ03_RS19155	ENOG4105D7K	pfkb domain protein
HZZ03_RS19165	ENOG4105C5I	Dehydrogenase
HZZ03_RS19170	ENOG4106JH6	(LipO)protein
HZZ03_RS19180	ENOG4105MVF	Transcriptional regulator
HZZ03_RS19190	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HZZ03_RS19195	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
HZZ03_RS19205	ENOG4105MEV	Acyl-transferase
HZZ03_RS19215	ENOG4105D3W	isochorismatase
HZZ03_RS19220	ENOG4105CMG	Carbohydrate kinase
HZZ03_RS19225	ENOG4105C93	Xylose Isomerase
HZZ03_RS19230	ENOG4105DFW	ABC transporter
HZZ03_RS19240	ENOG4108HWW	ABC transporter
HZZ03_RS19245	ENOG4105T16	Transcriptional regulator (AraC family)
HZZ03_RS19250	ENOG4108UR8	BAX protein
HZZ03_RS19255	ENOG4107T9C	Alpha amylase catalytic region
HZZ03_RS19260	ENOG4105JKW	Valine--pyruvate aminotransferase
HZZ03_RS19265	ENOG4105CJQ	hydrolase, family 31
HZZ03_RS19270	ENOG4105CT4	transporter
HZZ03_RS19300	ENOG4107S5I	aldo keto reductase
HZZ03_RS19305	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HZZ03_RS19310	ENOG4107XAN	XdhC and CoxI family
HZZ03_RS19315	ENOG4105C7W	Xanthine dehydrogenase
HZZ03_RS19320	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
HZZ03_RS19325	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
HZZ03_RS19335	ENOG4105EQ2	LysR family Transcriptional regulator
HZZ03_RS19340	ENOG4107RTG	Major Facilitator superfamily
HZZ03_RS19345	ENOG4105DQ4	alcohol dehydrogenase
HZZ03_RS19350	ENOG4105ENX	hydrolase
HZZ03_RS19365	ENOG4107ZY3	Histidine kinase
HZZ03_RS19370	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HZZ03_RS19375	ENOG4105VT2	5-hydroxyisourate hydrolase
HZZ03_RS19390	ENOG4105EAF	CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26)
HZZ03_RS19395	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HZZ03_RS19400	ENOG4105CTQ	phosphohexokinase
HZZ03_RS19405	ENOG41076HS	cation diffusion facilitator family transporter
HZZ03_RS19410	ENOG4105FMW	periplasmic
HZZ03_RS19415	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HZZ03_RS19420	ENOG4105E0F	Histidine kinase
HZZ03_RS19425	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HZZ03_RS19430	ENOG4105D7W	serine acetyltransferase
HZZ03_RS19435	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HZZ03_RS19440	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
HZZ03_RS19445	ENOG4105VW4	glutaredoxin 3
HZZ03_RS19450	ENOG4107YZP	Rhodanese domain protein
HZZ03_RS19455	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HZZ03_RS19460	ENOG41063SB	peptidase
HZZ03_RS19465	ENOG4105PXI	polysaccharide deacetylase
HZZ03_RS19470	ENOG4106WTF	Glycosyl transferase, family 2
HZZ03_RS19475	ENOG4105CPQ	Dehydrogenase
HZZ03_RS19480	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HZZ03_RS19485	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
HZZ03_RS19490	ENOG4105XA0	heptosyltransferase ii
HZZ03_RS19495	ENOG4105D16	lipopolysaccharide heptosyltransferase i
HZZ03_RS19500	ENOG4105DKP	glycosyl transferase, family 9
HZZ03_RS19505	ENOG4107SBE	Glycosyl transferase (Group 1
HZZ03_RS19510	ENOG4107TYR	Glycosyl Transferase
HZZ03_RS19520	ENOG4105K64	Glycosyl transferase, family 2
HZZ03_RS19535	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HZZ03_RS19540	ENOG4106WTF	Glycosyl transferase, family 2
HZZ03_RS19545	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HZZ03_RS19550	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HZZ03_RS19555	ENOG4105W0E	50S ribosomal protein L33
HZZ03_RS19560	ENOG4105KDC	50s ribosomal protein l28
HZZ03_RS19565	ENOG4105W5Q	DNA repair protein (RadC
HZZ03_RS19570	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HZZ03_RS19575	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HZZ03_RS19580	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
HZZ03_RS19585	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HZZ03_RS19590	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HZZ03_RS19595	ENOG4105DSJ	YicC domain protein
HZZ03_RS19600	ENOG4105EN6	Membrane
HZZ03_RS19605	ENOG410649J	Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity)
HZZ03_RS19610	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HZZ03_RS19620	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HZZ03_RS19625	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
HZZ03_RS19630	ENOG4105CB5	ATP-dependent DNA helicase recG
HZZ03_RS19640	ENOG4108VCD	Chaperone
HZZ03_RS19645	ENOG4105CW0	outer membrane usher protein
HZZ03_RS19670	ENOG4105C2W	permease
HZZ03_RS19675	ENOG4105JV1	AsmA family
HZZ03_RS19680	ENOG4105SUU	thioesterase domain
HZZ03_RS19685	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HZZ03_RS19690	ENOG4107S2Z	UPF0761 membrane protein
HZZ03_RS19695	ENOG4105EJU	HAD-superfamily hydrolase subfamily IA variant 3
HZZ03_RS19700	ENOG4105E98	transcriptional regulator DeoR family
HZZ03_RS19705	ENOG4108MGF	sugar kinase
HZZ03_RS19710	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HZZ03_RS19715	ENOG4105D2M	Aldolase
HZZ03_RS19720	ENOG4107QKS	N-acylglucosamine 2-epimerase
HZZ03_RS19725	ENOG4107WI4	Aldose-1-epimerase
HZZ03_RS19730	ENOG4105CJQ	hydrolase, family 31
HZZ03_RS19740	ENOG4105CT4	transporter
HZZ03_RS19745	ENOG4105CT4	transporter
HZZ03_RS19750	ENOG4108KUC	Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is
HZZ03_RS19755	ENOG4105CI3	gtp-binding protein typa
HZZ03_RS19760	ENOG4105C5F	glutamine synthetase
HZZ03_RS19765	ENOG4105CUX	Signal transduction histidine kinase
HZZ03_RS19770	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HZZ03_RS19775	ENOG4106FIY	
HZZ03_RS19780	ENOG4105D4P	Coproporphyrinogen iii oxidase
HZZ03_RS19785	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
HZZ03_RS19795	ENOG4105C2M	dna polymerase I
HZZ03_RS19800	ENOG4106HNH	Acyl-transferase
HZZ03_RS19805	ENOG4108Z33	Thiol disulfide Interchange Protein
HZZ03_RS19810	ENOG4105E27	serine threonine protein kinase
HZZ03_RS19815	ENOG4105PC1	Conserved Protein
HZZ03_RS19820	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HZZ03_RS19825	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
HZZ03_RS19850	ENOG4107EJG	GntR family transcriptional regulator
HZZ03_RS19855	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HZZ03_RS19860	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ03_RS19865	ENOG4108RVA	ribokinase
HZZ03_RS19870	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HZZ03_RS19875	ENOG4105CNN	ABC, transporter
HZZ03_RS19880	ENOG4105C2J	ABC transporter
HZZ03_RS19885	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
HZZ03_RS19890	ENOG4105DFH	Transport of potassium into the cell (By similarity)
HZZ03_RS19900	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
HZZ03_RS19905	ENOG4105CU9	asparagine synthetase A
HZZ03_RS19910	ENOG4108VVK	transcriptional Regulator, AsnC
HZZ03_RS19915	ENOG4105QTB	Flavodoxin
HZZ03_RS19920	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HZZ03_RS19925	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HZZ03_RS19930	ENOG4105GXX	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation
HZZ03_RS19935	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
HZZ03_RS19945	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HZZ03_RS19950	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HZZ03_RS19955	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HZZ03_RS19960	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HZZ03_RS19965	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HZZ03_RS19970	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HZZ03_RS19975	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HZZ03_RS19980	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HZZ03_RS19995	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
HZZ03_RS20000	ENOG4105C8U	phosphate abc transporter
HZZ03_RS20005	ENOG4105E2Z	phosphate ABC transporter (Permease
HZZ03_RS20010	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HZZ03_RS20020	ENOG4105DYC	esterase
HZZ03_RS20025	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
HZZ03_RS20030	ENOG4105C7N	Xanthine uracil vitamin C permease
HZZ03_RS20035	ENOG4108YYH	Nadph-dependent fmn reductase
HZZ03_RS20040	ENOG4105E8Q	phosphopantetheinyl transferase
HZZ03_RS20060	ENOG4108UMN	azlc family
HZZ03_RS20085	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HZZ03_RS20090	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HZZ03_RS20100	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HZZ03_RS20105	ENOG4105VG0	50S ribosomal protein l34