locus-tag	class	description
HZZ03_RS00010	COG0592	DNA-directed DNA polymerase activity
HZZ03_RS00020	COG0187	DNA topoisomerase II activity
HZZ03_RS00025	COG0561	phosphatase activity
HZZ03_RS00035	COG2186	Transcriptional regulator
HZZ03_RS00040	COG3734	2-keto-3-deoxy-galactonokinase
HZZ03_RS00045	COG0800	Aldolase
HZZ03_RS00055	COG2271	Major facilitator Superfamily
HZZ03_RS00065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HZZ03_RS00070	COG0823	Involved in the tonB-independent uptake of proteins
HZZ03_RS00075	COG5645	(Lipo)protein
HZZ03_RS00090	COG2188	Transcriptional regulator
HZZ03_RS00105	COG2149	membrane
HZZ03_RS00120	COG2814	Major facilitator Superfamily
HZZ03_RS00260	COG0515	serine threonine protein kinase
HZZ03_RS00275	COG3501	Rhs element vgr protein
HZZ03_RS00295	COG3209	COG3209 Rhs family protein
HZZ03_RS00325	COG3501	Rhs element vgr protein
HZZ03_RS00420	COG0149	triose-phosphate isomerase activity
HZZ03_RS00430	COG3152	Membrane
HZZ03_RS00440	COG1494	fructose-1,6-bisphosphatase
HZZ03_RS00445	COG3722	fumarate hydratase activity
HZZ03_RS00455	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HZZ03_RS00455	COG2213	PTS system mannitol-specific
HZZ03_RS00460	COG0625	glutathione transferase activity
HZZ03_RS00470	COG3276	selenocysteine insertion sequence binding
HZZ03_RS00475	COG1454	alcohol dehydrogenase
HZZ03_RS00480	COG1940	carbohydrate kinase activity
HZZ03_RS00495	COG2211	Major facilitator Superfamily
HZZ03_RS00505	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
HZZ03_RS00520	COG2864	formate dehydrogenase
HZZ03_RS00525	COG0437	4 iron, 4 sulfur cluster binding
HZZ03_RS00550	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HZZ03_RS00570	COG2211	Major facilitator Superfamily
HZZ03_RS00580	COG1454	alcohol dehydrogenase
HZZ03_RS00600	COG4977	sequence-specific DNA binding
HZZ03_RS00615	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HZZ03_RS00620	COG2258	MOSC domain
HZZ03_RS00630	COG2186	Transcriptional regulator
HZZ03_RS00660	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HZZ03_RS00675	COG1575	Belongs to the MenA family. Type 1 subfamily
HZZ03_RS00685	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HZZ03_RS00690	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HZZ03_RS00695	COG1609	Transcriptional regulator
HZZ03_RS00700	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HZZ03_RS00715	COG0626	cystathionine gamma-synthase activity
HZZ03_RS00720	COG0527	aspartate kinase activity
HZZ03_RS00720	COG0460	homoserine dehydrogenase
HZZ03_RS00725	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HZZ03_RS00745	COG3121	Chaperone
HZZ03_RS00770	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HZZ03_RS00790	COG0583	DNA-binding transcription factor activity
HZZ03_RS00865	COG3085	chromosome segregation
HZZ03_RS00870	COG0606	chelatase, subunit chli
HZZ03_RS00885	COG3978	acetolactate synthase activity
HZZ03_RS00905	COG0583	DNA-binding transcription factor activity
HZZ03_RS00920	COG0210	DNA helicase
HZZ03_RS00935	COG3118	belongs to the thioredoxin family
HZZ03_RS00940	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HZZ03_RS00945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HZZ03_RS00955	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HZZ03_RS00960	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HZZ03_RS00965	COG0456	acetyltransferase
HZZ03_RS00970	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HZZ03_RS00975	COG2244	polysaccharide biosynthetic process
HZZ03_RS01025	COG3071	HemY protein
HZZ03_RS01030	COG2959	enzyme of heme biosynthesis
HZZ03_RS01055	COG5567	small periplasmic lipoprotein
HZZ03_RS01065	COG3159	Protein conserved in bacteria
HZZ03_RS01075	COG1011	Hydrolase
HZZ03_RS01080	COG0210	DNA helicase
HZZ03_RS01105	COG2050	protein possibly involved in aromatic compounds catabolism
HZZ03_RS01110	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
HZZ03_RS01120	COG1280	lysine exporter protein (LysE YggA)
HZZ03_RS01125	COG1280	lysine exporter protein (LysE YggA)
HZZ03_RS01130	COG2267	carboxylic ester hydrolase activity
HZZ03_RS01135	COG0561	phosphatase activity
HZZ03_RS01140	COG0697	spore germination
HZZ03_RS01145	COG0583	DNA-binding transcription factor activity
HZZ03_RS01185	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HZZ03_RS01190	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HZZ03_RS01195	COG0805	protein transport
HZZ03_RS01245	COG1739	Uncharacterized protein family UPF0029
HZZ03_RS01280	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HZZ03_RS01325	COG0250	Participates in transcription elongation, termination and antitermination
HZZ03_RS01365	COG2207	Transcriptional regulator
HZZ03_RS01365	COG3708	Transcriptional regulator
HZZ03_RS01370	COG1447	Phosphotransferase system cellobiose-specific component IIA
HZZ03_RS01380	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HZZ03_RS01390	COG2104	thiamine diphosphate biosynthetic process
HZZ03_RS01395	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HZZ03_RS01410	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
HZZ03_RS01445	COG0151	Belongs to the GarS family
HZZ03_RS01485	COG1126	abc transporter atp-binding protein
HZZ03_RS01490	COG0765	amino acid transport
HZZ03_RS01495	COG4597	amino acid ABC transporter
HZZ03_RS01500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HZZ03_RS01510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HZZ03_RS01515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HZZ03_RS01520	COG1309	transcriptional regulator
HZZ03_RS01550	COG4145	pantothenate transmembrane transporter activity
HZZ03_RS01555	COG3924	membrane
HZZ03_RS01560	COG0439	Biotin carboxylase
HZZ03_RS01565	COG0511	ligase activity, forming carbon-carbon bonds
HZZ03_RS01570	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HZZ03_RS01585	COG0604	alcohol dehydrogenase
HZZ03_RS01590	COG2199	diguanylate cyclase activity
HZZ03_RS01590	COG2200	EAL domain
HZZ03_RS01595	COG1077	Cell shape determining protein MreB Mrl
HZZ03_RS01600	COG1792	Involved in formation and maintenance of cell shape
HZZ03_RS01605	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HZZ03_RS01615	COG1530	ribonuclease E activity
HZZ03_RS01620	COG3164	Protein of unknown function
HZZ03_RS01625	COG0312	modulator of DNA gyrase
HZZ03_RS01630	COG0583	DNA-binding transcription factor activity
HZZ03_RS01645	COG1289	transmembrane transporter activity
HZZ03_RS01655	COG2732	(Barnase) inhibitor
HZZ03_RS01680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HZZ03_RS01685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HZZ03_RS01690	COG3105	Protein conserved in bacteria
HZZ03_RS01695	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HZZ03_RS01710	COG0625	glutathione transferase activity
HZZ03_RS01715	COG2969	positive regulation of protein catabolic process
HZZ03_RS01740	COG2731	YhcH YjgK YiaL family protein
HZZ03_RS01750	COG0493	'glutamate synthase
HZZ03_RS01755	COG0070	glutamate synthase
HZZ03_RS01755	COG0069	glutamate synthase activity
HZZ03_RS01755	COG0067	glutamate synthase
HZZ03_RS01760	COG1242	4 iron, 4 sulfur cluster binding
HZZ03_RS01765	COG5002	protein histidine kinase activity
HZZ03_RS01765	COG2198	Histidine kinase
HZZ03_RS01765	COG0784	Response regulator, receiver
HZZ03_RS01770	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HZZ03_RS01780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HZZ03_RS01800	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HZZ03_RS01805	COG1137	ATPase activity
HZZ03_RS01810	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HZZ03_RS01815	COG3117	lipopolysaccharide transmembrane transporter activity
HZZ03_RS01820	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HZZ03_RS01830	COG0530	calcium, potassium:sodium antiporter activity
HZZ03_RS01835	COG1127	ABC transporter
HZZ03_RS01840	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HZZ03_RS01845	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HZZ03_RS01850	COG2854	intermembrane phospholipid transfer
HZZ03_RS01855	COG3113	response to antibiotic
HZZ03_RS01860	COG5007	Belongs to the BolA IbaG family
HZZ03_RS01870	COG3423	Transcriptional regulator
HZZ03_RS01875	COG0142	geranyltranstransferase activity
HZZ03_RS01890	COG0697	spore germination
HZZ03_RS01900	COG0642	Histidine kinase
HZZ03_RS01905	COG0745	RESPONSE REGULATOR receiver
HZZ03_RS01910	COG2027	D-alanyl-D-alanine carboxypeptidase
HZZ03_RS01915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HZZ03_RS01920	COG1534	Rna-binding protein
HZZ03_RS01930	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HZZ03_RS01935	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HZZ03_RS01945	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HZZ03_RS01965	COG0195	Participates in both transcription termination and antitermination
HZZ03_RS02005	COG0513	Belongs to the DEAD box helicase family
HZZ03_RS02010	COG0814	amino acid
HZZ03_RS02015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HZZ03_RS02020	COG0826	peptidase U32
HZZ03_RS02025	COG0826	peptidase U32
HZZ03_RS02030	COG3154	lipid carrier protein
HZZ03_RS02035	COG3153	acetyltransferase
HZZ03_RS02050	COG0693	protein deglycase activity
HZZ03_RS02055	COG0702	epimerase
HZZ03_RS02060	COG0701	Predicted permease
HZZ03_RS02065	COG2823	Periplasmic or secreted lipoprotein
HZZ03_RS02080	COG3107	peptidoglycan biosynthetic process
HZZ03_RS02085	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HZZ03_RS02100	COG1741	Belongs to the pirin family
HZZ03_RS02105	COG0583	DNA-binding transcription factor activity
HZZ03_RS02135	COG3152	Membrane
HZZ03_RS02140	COG0435	Glutathione S-transferase
HZZ03_RS02145	COG2259	Doxx family
HZZ03_RS02150	COG3539	Fimbrial protein
HZZ03_RS02170	COG3539	Fimbrial protein
HZZ03_RS02175	COG3121	Chaperone
HZZ03_RS02180	COG3188	usher protein
HZZ03_RS02205	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HZZ03_RS02210	COG4575	ribosome binding
HZZ03_RS02215	COG1422	Protein of unknown function (DUF1090)
HZZ03_RS02225	COG0586	Pfam SNARE associated Golgi protein
HZZ03_RS02230	COG2186	Transcriptional regulator
HZZ03_RS02235	COG2271	Major facilitator Superfamily
HZZ03_RS02245	COG2721	sulfolactate sulfo-lyase activity
HZZ03_RS02265	COG0673	inositol 2-dehydrogenase activity
HZZ03_RS02270	COG2949	membrane
HZZ03_RS02275	COG1451	nucleotide metabolic process
HZZ03_RS02285	COG1902	pentaerythritol trinitrate reductase activity
HZZ03_RS02285	COG0446	pyridine nucleotide-disulphide oxidoreductase
HZZ03_RS02295	COG3706	GGDEF domain
HZZ03_RS02300	COG0840	transmembrane signaling receptor activity
HZZ03_RS02305	COG0840	transmembrane signaling receptor activity
HZZ03_RS02310	COG1695	Transcriptional regulator
HZZ03_RS02315	COG2375	cellular response to nickel ion
HZZ03_RS02320	COG1032	radical SAM domain protein
HZZ03_RS02325	COG0251	oxidation-reduction process
HZZ03_RS02340	COG1438	arginine binding
HZZ03_RS02345	COG1288	antiporter activity
HZZ03_RS02350	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HZZ03_RS02355	COG0549	Belongs to the carbamate kinase family
HZZ03_RS02360	COG2235	arginine
HZZ03_RS02370	COG2731	YhcH YjgK YiaL family protein
HZZ03_RS02400	COG4269	membrane
HZZ03_RS02410	COG2927	DNA polymerase III (CHI subunit)
HZZ03_RS02420	COG0795	lipopolysaccharide-transporting ATPase activity
HZZ03_RS02425	COG0795	lipopolysaccharide-transporting ATPase activity
HZZ03_RS02445	COG1064	alcohol dehydrogenase
HZZ03_RS02450	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HZZ03_RS02495	COG3157	Type VI secretion system effector, Hcp
HZZ03_RS02505	COG2733	membrane
HZZ03_RS02510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HZZ03_RS02530	COG2182	Extracellular solute-binding protein
HZZ03_RS02535	COG1175	transmembrane transport
HZZ03_RS02540	COG3833	ABC-type maltose transport systems, permease component
HZZ03_RS02545	COG3867	Arabinogalactan endo-beta-1,4-galactanase
HZZ03_RS02550	COG1874	Beta-galactosidase
HZZ03_RS02565	COG1609	Transcriptional regulator
HZZ03_RS02575	COG1566	PFAM secretion protein HlyD family protein
HZZ03_RS02590	COG1609	Transcriptional regulator
HZZ03_RS02595	COG1263	PTS System
HZZ03_RS02595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZZ03_RS02600	COG2723	6-phospho-beta-galactosidase activity
HZZ03_RS02605	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HZZ03_RS02610	COG0402	S-adenosylhomocysteine deaminase activity
HZZ03_RS02625	COG0840	transmembrane signaling receptor activity
HZZ03_RS02635	COG3706	GGDEF domain
HZZ03_RS02645	COG1484	DNA-dependent DNA replication
HZZ03_RS02655	COG1764	response to oxidative stress
HZZ03_RS02660	COG1846	Transcriptional regulator
HZZ03_RS02670	COG2966	Psort location CytoplasmicMembrane, score
HZZ03_RS02675	COG2197	response regulator
HZZ03_RS02680	COG2197	response regulator
HZZ03_RS02685	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HZZ03_RS02690	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HZZ03_RS02695	COG4114	ferric iron reductase
HZZ03_RS02700	COG3706	GGDEF domain
HZZ03_RS02730	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HZZ03_RS02735	COG0456	acetyltransferase
HZZ03_RS02740	COG1011	Hydrolase
HZZ03_RS02750	COG2823	Periplasmic or secreted lipoprotein
HZZ03_RS02760	COG4667	esterase of the alpha-beta hydrolase superfamily
HZZ03_RS02765	COG0084	hydrolase, TatD family'
HZZ03_RS02770	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HZZ03_RS02800	COG3726	membrane protein affecting hemolysin expression
HZZ03_RS02805	COG0560	Phosphoserine phosphatase
HZZ03_RS02810	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HZZ03_RS02845	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HZZ03_RS02845	COG1215	transferase activity, transferring glycosyl groups
HZZ03_RS02875	COG0488	(ABC) transporter
HZZ03_RS02880	COG0741	lytic transglycosylase activity
HZZ03_RS02900	COG3708	Transcriptional regulator
HZZ03_RS02900	COG2207	Transcriptional regulator
HZZ03_RS02905	COG3045	CreA protein
HZZ03_RS02910	COG0745	RESPONSE REGULATOR receiver
HZZ03_RS02915	COG2205	protein histidine kinase activity
HZZ03_RS02920	COG4452	Inner membrane protein CreD
HZZ03_RS02925	COG0745	RESPONSE REGULATOR receiver
HZZ03_RS02935	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HZZ03_RS02945	COG0527	aspartate kinase activity
HZZ03_RS02945	COG0460	homoserine dehydrogenase
HZZ03_RS02955	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HZZ03_RS02965	COG1115	amino acid carrier protein
HZZ03_RS02975	COG0521	Mo-molybdopterin cofactor biosynthetic process
HZZ03_RS02985	COG1584	GPR1 FUN34 yaaH family protein
HZZ03_RS03030	COG0583	DNA-binding transcription factor activity
HZZ03_RS03040	COG0196	riboflavin kinase activity
HZZ03_RS03055	COG1047	Peptidyl-prolyl cis-trans
HZZ03_RS03075	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HZZ03_RS03085	COG0383	alpha-mannosidase activity
HZZ03_RS03090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HZZ03_RS03100	COG1737	Transcriptional regulator
HZZ03_RS03110	COG0505	Belongs to the CarA family
HZZ03_RS03140	COG1280	lysine exporter protein (LysE YggA)
HZZ03_RS03165	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HZZ03_RS03170	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HZZ03_RS03175	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HZZ03_RS03185	COG0564	pseudouridine synthase activity
HZZ03_RS03195	COG0417	DNA replication proofreading
HZZ03_RS03200	COG0235	Class ii aldolase
HZZ03_RS03205	COG2160	L-arabinose isomerase activity
HZZ03_RS03215	COG4977	sequence-specific DNA binding
HZZ03_RS03220	COG0586	Pfam SNARE associated Golgi protein
HZZ03_RS03225	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
HZZ03_RS03230	COG1178	ABC-type Fe3 transport system permease component
HZZ03_RS03250	COG2814	Major facilitator Superfamily
HZZ03_RS03285	COG0028	Belongs to the TPP enzyme family
HZZ03_RS03295	COG1609	Transcriptional regulator
HZZ03_RS03315	COG0768	penicillin binding
HZZ03_RS03325	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HZZ03_RS03340	COG0772	Belongs to the SEDS family
HZZ03_RS03355	COG1181	Belongs to the D-alanine--D-alanine ligase family
HZZ03_RS03365	COG0849	cell division
HZZ03_RS03370	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HZZ03_RS03390	COG0494	nUDIX hydrolase
HZZ03_RS03410	COG0516	GMP reductase activity
HZZ03_RS03415	COG1459	type II secretion system
HZZ03_RS03420	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HZZ03_RS03425	COG4969	Belongs to the N-Me-Phe pilin family
HZZ03_RS03440	COG3725	Membrane protein required for beta-lactamase induction
HZZ03_RS03445	COG3940	Belongs to the glycosyl hydrolase 43 family
HZZ03_RS03450	COG2211	Major facilitator Superfamily
HZZ03_RS03455	COG1113	amino acid transport
HZZ03_RS03460	COG2186	Transcriptional regulator
HZZ03_RS03465	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HZZ03_RS03470	COG0508	dehydrogenase complex catalyzes the overall conversion of
HZZ03_RS03475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HZZ03_RS03525	COG2132	Multicopper oxidase
HZZ03_RS03530	COG4993	Dehydrogenase
HZZ03_RS03540	COG0288	reversible hydration of carbon dioxide
HZZ03_RS03545	COG1131	(ABC) transporter
HZZ03_RS03550	COG0842	Transport permease protein
HZZ03_RS03555	COG0726	polysaccharide deacetylase
HZZ03_RS03575	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HZZ03_RS03580	COG0617	tRNA 3'-terminal CCA addition
HZZ03_RS03590	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HZZ03_RS03600	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HZZ03_RS03605	COG1643	Atp-dependent helicase
HZZ03_RS03610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HZZ03_RS03615	COG4774	siderophore transport
HZZ03_RS03620	COG1120	ATPase activity
HZZ03_RS03625	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HZZ03_RS03630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HZZ03_RS03650	COG2860	membrane
HZZ03_RS03670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HZZ03_RS03715	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HZZ03_RS03725	COG0575	Belongs to the CDS family
HZZ03_RS03730	COG0750	zinc metalloprotease
HZZ03_RS03745	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HZZ03_RS03790	COG0346	lactoylglutathione lyase activity
HZZ03_RS03805	COG4568	rho-dependent transcription termination
HZZ03_RS03815	COG4681	YaeQ
HZZ03_RS03820	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HZZ03_RS03825	COG3015	lipoprotein NlpE involved in copper resistance
HZZ03_RS03835	COG1720	tRNA m6t6A37 methyltransferase activity
HZZ03_RS03850	COG2011	ABC-type metal ion transport system permease component
HZZ03_RS03860	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HZZ03_RS03895	COG0583	DNA-binding transcription factor activity
HZZ03_RS03900	COG3021	interspecies interaction between organisms
HZZ03_RS03905	COG2226	methyltransferase
HZZ03_RS03910	COG1388	LysM domain
HZZ03_RS03910	COG0741	lytic transglycosylase activity
HZZ03_RS03920	COG2226	methyltransferase
HZZ03_RS03940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HZZ03_RS03955	COG0121	glutamine amidotransferase
HZZ03_RS03960	COG3034	peptidoglycan biosynthetic process
HZZ03_RS03970	COG2195	Cleaves the N-terminal amino acid of tripeptides
HZZ03_RS03990	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HZZ03_RS04010	COG0582	viral genome integration into host DNA
HZZ03_RS04070	COG1192	Involved in chromosome partitioning
HZZ03_RS04125	COG2195	Cleaves the N-terminal amino acid of tripeptides
HZZ03_RS04130	COG0747	negative chemotaxis
HZZ03_RS04195	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HZZ03_RS04200	COG0251	oxidation-reduction process
HZZ03_RS04205	COG1309	transcriptional regulator
HZZ03_RS04230	COG2223	nitrite transmembrane transporter activity
HZZ03_RS04255	COG2011	ABC-type metal ion transport system permease component
HZZ03_RS04260	COG1464	Belongs to the NlpA lipoprotein family
HZZ03_RS04270	COG3479	Phenolic acid decarboxylase
HZZ03_RS04290	COG0583	DNA-binding transcription factor activity
HZZ03_RS04295	COG4993	Dehydrogenase
HZZ03_RS04300	COG0628	permease
HZZ03_RS04305	COG0659	secondary active sulfate transmembrane transporter activity
HZZ03_RS04310	COG0288	reversible hydration of carbon dioxide
HZZ03_RS04320	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HZZ03_RS04330	COG0494	nUDIX hydrolase
HZZ03_RS04335	COG1349	DNA-binding transcription factor activity
HZZ03_RS04340	COG1560	Kdo2-lipid A biosynthetic process
HZZ03_RS04345	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HZZ03_RS04360	COG1271	oxidase subunit
HZZ03_RS04370	COG3383	formate dehydrogenase (NAD+) activity
HZZ03_RS04375	COG0833	amino acid
HZZ03_RS04380	COG2040	homocysteine
HZZ03_RS04385	COG4521	taurine ABC transporter
HZZ03_RS04395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HZZ03_RS04400	COG2175	clavaminate synthase activity
HZZ03_RS04415	COG0113	porphobilinogen synthase activity
HZZ03_RS04420	COG1546	Belongs to the CinA family
HZZ03_RS04430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HZZ03_RS04435	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HZZ03_RS04445	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HZZ03_RS04465	COG1181	Belongs to the D-alanine--D-alanine ligase family
HZZ03_RS04475	COG2814	Major facilitator Superfamily
HZZ03_RS04485	COG2814	Major facilitator Superfamily
HZZ03_RS04490	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HZZ03_RS04500	COG2323	membrane
HZZ03_RS04510	COG3416	Protein conserved in bacteria
HZZ03_RS04525	COG4126	flavin adenine dinucleotide binding
HZZ03_RS04540	COG1940	carbohydrate kinase activity
HZZ03_RS04545	COG0419	ATPase involved in DNA repair
HZZ03_RS04550	COG0420	3'-5' exonuclease activity
HZZ03_RS04560	COG5002	protein histidine kinase activity
HZZ03_RS04575	COG0366	Alpha amylase catalytic
HZZ03_RS04590	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
HZZ03_RS04605	COG1862	Preprotein translocase
HZZ03_RS04610	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HZZ03_RS04615	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HZZ03_RS04620	COG3248	Nucleoside-binding outer membrane protein
HZZ03_RS04625	COG4238	major outer membrane lipoprotein
HZZ03_RS04635	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HZZ03_RS04635	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HZZ03_RS04650	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HZZ03_RS04655	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HZZ03_RS04660	COG0667	Aldo Keto reductase
HZZ03_RS04670	COG0142	geranyltranstransferase activity
HZZ03_RS04690	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HZZ03_RS04700	COG2814	Major facilitator Superfamily
HZZ03_RS04710	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HZZ03_RS04715	COG1845	cytochrome c oxidase, subunit III
HZZ03_RS04720	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HZZ03_RS04725	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HZZ03_RS04730	COG0443	Heat shock 70 kDa protein
HZZ03_RS04740	COG2223	nitrite transmembrane transporter activity
HZZ03_RS04745	COG3056	Lipoprotein
HZZ03_RS04750	COG0271	Belongs to the BolA IbaG family
HZZ03_RS04770	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HZZ03_RS04775	COG0776	regulation of translation
HZZ03_RS04780	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HZZ03_RS04785	COG1555	photosystem II stabilization
HZZ03_RS04790	COG0824	Thioesterase
HZZ03_RS04805	COG4533	DNA binding
HZZ03_RS04830	COG1522	sequence-specific DNA binding
HZZ03_RS04835	COG1132	(ABC) transporter
HZZ03_RS04840	COG1132	(ABC) transporter
HZZ03_RS04845	COG0347	Belongs to the P(II) protein family
HZZ03_RS04850	COG0004	ammonium transporteR
HZZ03_RS04855	COG1946	Acyl-CoA thioesterase
HZZ03_RS04860	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HZZ03_RS04865	COG3695	enzyme binding
HZZ03_RS04885	COG1857	crispr-associated protein
HZZ03_RS04900	COG1518	maintenance of DNA repeat elements
HZZ03_RS04905	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HZZ03_RS04945	COG1214	PFAM Peptidase M22, glycoprotease
HZZ03_RS04945	COG0456	acetyltransferase
HZZ03_RS04950	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HZZ03_RS04955	COG2011	ABC-type metal ion transport system permease component
HZZ03_RS04975	COG0840	transmembrane signaling receptor activity
HZZ03_RS04995	COG0110	maltose O-acetyltransferase activity
HZZ03_RS05010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HZZ03_RS05015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HZZ03_RS05020	COG1309	transcriptional regulator
HZZ03_RS05025	COG3264	Mechanosensitive ion channel
HZZ03_RS05025	COG1196	nuclear chromosome segregation
HZZ03_RS05035	COG3923	Primosomal replication protein n
HZZ03_RS05040	COG2832	Protein of unknown function (DUF454)
HZZ03_RS05100	COG3835	regulator
HZZ03_RS05105	COG2610	gluconate transmembrane transporter activity
HZZ03_RS05110	COG1929	Belongs to the glycerate kinase type-1 family
HZZ03_RS05120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HZZ03_RS05125	COG4651	solute:proton antiporter activity
HZZ03_RS05125	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HZZ03_RS05130	COG0737	Belongs to the 5'-nucleotidase family
HZZ03_RS05140	COG3735	TraB family
HZZ03_RS05165	COG1585	Membrane protein implicated in regulation of membrane protease activity
HZZ03_RS05170	COG0330	HflC and HflK could
HZZ03_RS05175	COG3118	belongs to the thioredoxin family
HZZ03_RS05180	COG0300	oxidoreductase activity
HZZ03_RS05185	COG2755	lipolytic protein G-D-S-L family
HZZ03_RS05190	COG4181	ATPase activity
HZZ03_RS05195	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HZZ03_RS05215	COG0626	cystathionine gamma-synthase activity
HZZ03_RS05220	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HZZ03_RS05225	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HZZ03_RS05235	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HZZ03_RS05245	COG1609	Transcriptional regulator
HZZ03_RS05250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZZ03_RS05250	COG1263	PTS System
HZZ03_RS05250	COG2190	(PTS) system
HZZ03_RS05255	COG2501	S4 domain
HZZ03_RS05270	COG0582	viral genome integration into host DNA
HZZ03_RS05300	COG3772	lysozyme
HZZ03_RS05370	COG3121	Chaperone
HZZ03_RS05375	COG3188	usher protein
HZZ03_RS05410	COG2885	chlorophyll binding
HZZ03_RS05425	COG3501	Rhs element vgr protein
HZZ03_RS05450	COG0840	transmembrane signaling receptor activity
HZZ03_RS05465	COG2977	Belongs to the P-Pant transferase superfamily
HZZ03_RS05470	COG4771	TonB-dependent receptor
HZZ03_RS05475	COG2382	esterase
HZZ03_RS05480	COG3251	PFAM MbtH domain protein
HZZ03_RS05485	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HZZ03_RS05485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HZZ03_RS05505	COG0436	Aminotransferase
HZZ03_RS05510	COG0583	DNA-binding transcription factor activity
HZZ03_RS05520	COG3634	alkyl hydroperoxide reductase activity
HZZ03_RS05525	COG0589	response to stress
HZZ03_RS05530	COG1063	alcohol dehydrogenase
HZZ03_RS05535	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HZZ03_RS05545	COG1653	transport
HZZ03_RS05560	COG3842	ATPase activity
HZZ03_RS05565	COG0366	Alpha amylase catalytic
HZZ03_RS05570	COG0366	Alpha amylase catalytic
HZZ03_RS05580	COG3719	Belongs to the RNase T2 family
HZZ03_RS05585	COG3069	C4-dicarboxylate transmembrane transporter activity
HZZ03_RS05605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HZZ03_RS05620	COG0583	DNA-binding transcription factor activity
HZZ03_RS05635	COG1686	Belongs to the peptidase S11 family
HZZ03_RS05640	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HZZ03_RS05645	COG0772	Belongs to the SEDS family
HZZ03_RS05650	COG0768	penicillin binding
HZZ03_RS05660	COG0799	negative regulation of ribosome biogenesis
HZZ03_RS05670	COG1466	dna polymerase III delta subunit
HZZ03_RS05685	COG2888	peptidyl-tyrosine sulfation
HZZ03_RS05690	COG1126	abc transporter atp-binding protein
HZZ03_RS05695	COG0765	amino acid transport
HZZ03_RS05700	COG0765	amino acid transport
HZZ03_RS05710	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HZZ03_RS05725	COG1702	phosphate starvation-inducible protein PhoH
HZZ03_RS05735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HZZ03_RS05775	COG0367	asparagine synthase
HZZ03_RS05780	COG0647	UMP catabolic process
HZZ03_RS05785	COG1940	carbohydrate kinase activity
HZZ03_RS05785	COG1846	Transcriptional regulator
HZZ03_RS05790	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HZZ03_RS05800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZZ03_RS05800	COG1263	PTS System
HZZ03_RS05800	COG2190	(PTS) system
HZZ03_RS05830	COG0735	belongs to the Fur family
HZZ03_RS05835	COG0716	FMN binding
HZZ03_RS05845	COG0596	Alpha beta hydrolase
HZZ03_RS05855	COG0033	Phosphoglucomutase
HZZ03_RS05860	COG0531	amino acid
HZZ03_RS05865	COG1982	Orn Lys Arg decarboxylase major
HZZ03_RS05875	COG0745	RESPONSE REGULATOR receiver
HZZ03_RS05880	COG2205	protein histidine kinase activity
HZZ03_RS05890	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HZZ03_RS05910	COG3272	Protein of unknown function (DUF1722)
HZZ03_RS05915	COG0415	Belongs to the DNA photolyase family
HZZ03_RS05920	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HZZ03_RS05925	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HZZ03_RS05930	COG1984	allophanate hydrolase subunit 2
HZZ03_RS05965	COG0372	Belongs to the citrate synthase family
HZZ03_RS05975	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HZZ03_RS05980	COG1053	succinate dehydrogenase
HZZ03_RS05985	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HZZ03_RS05990	COG0567	Dehydrogenase, E1 component
HZZ03_RS05995	COG0508	dehydrogenase complex catalyzes the overall conversion of
HZZ03_RS06005	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HZZ03_RS06010	COG2188	Transcriptional regulator
HZZ03_RS06015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HZZ03_RS06015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HZZ03_RS06015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HZZ03_RS06020	COG0383	alpha-mannosidase activity
HZZ03_RS06025	COG1271	oxidase subunit
HZZ03_RS06030	COG1294	oxidase, subunit
HZZ03_RS06035	COG4890	Cyd operon protein YbgT
HZZ03_RS06040	COG3790	cyd operon protein YbgE
HZZ03_RS06045	COG0824	Thioesterase
HZZ03_RS06050	COG0811	peptide transport
HZZ03_RS06055	COG0848	biopolymer transport protein
HZZ03_RS06060	COG3064	Membrane
HZZ03_RS06070	COG2885	chlorophyll binding
HZZ03_RS06075	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HZZ03_RS06115	COG3201	nicotinamide mononucleotide transporter
HZZ03_RS06120	COG1230	cation diffusion facilitator family transporter
HZZ03_RS06130	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HZZ03_RS06140	COG2017	converts alpha-aldose to the beta-anomer
HZZ03_RS06150	COG1085	galactose-1-phosphate uridylyltransferase
HZZ03_RS06160	COG1119	ATPase activity
HZZ03_RS06165	COG3585	molybdate ion transport
HZZ03_RS06165	COG2005	Transcriptional regulator
HZZ03_RS06175	COG0725	ABC transporter, periplasmic molybdate-binding protein
HZZ03_RS06180	COG4149	molybdate abc transporter
HZZ03_RS06190	COG0561	phosphatase activity
HZZ03_RS06200	COG4677	pectinesterase activity
HZZ03_RS06205	COG1881	PFAM PEBP family protein
HZZ03_RS06235	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HZZ03_RS06265	COG0521	Mo-molybdopterin cofactor biosynthetic process
HZZ03_RS06275	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HZZ03_RS06285	COG0670	Belongs to the BI1 family
HZZ03_RS06290	COG0392	lysyltransferase activity
HZZ03_RS06300	COG3568	Endonuclease Exonuclease Phosphatase
HZZ03_RS06310	COG0842	Transport permease protein
HZZ03_RS06315	COG0842	Transport permease protein
HZZ03_RS06320	COG1131	(ABC) transporter
HZZ03_RS06325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HZZ03_RS06330	COG1309	transcriptional regulator
HZZ03_RS06335	COG0513	Belongs to the DEAD box helicase family
HZZ03_RS06340	COG2723	6-phospho-beta-galactosidase activity
HZZ03_RS06345	COG2723	6-phospho-beta-galactosidase activity
HZZ03_RS06350	COG1263	PTS System
HZZ03_RS06350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZZ03_RS06350	COG2190	(PTS) system
HZZ03_RS06355	COG3711	transcriptional antiterminator
HZZ03_RS06360	COG1199	ATP-dependent helicase activity
HZZ03_RS06380	COG3121	Chaperone
HZZ03_RS06385	COG3539	Fimbrial protein
HZZ03_RS06390	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HZZ03_RS06400	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HZZ03_RS06405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HZZ03_RS06415	COG0668	transmembrane transport
HZZ03_RS06420	COG1126	abc transporter atp-binding protein
HZZ03_RS06425	COG0765	amino acid transport
HZZ03_RS06430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HZZ03_RS06445	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HZZ03_RS06450	COG2194	sulfuric ester hydrolase activity
HZZ03_RS06460	COG1321	iron dependent repressor
HZZ03_RS06465	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HZZ03_RS06470	COG1566	PFAM secretion protein HlyD family protein
HZZ03_RS06475	COG2814	Major facilitator Superfamily
HZZ03_RS06485	COG1376	ErfK ybiS ycfS ynhG family protein
HZZ03_RS06490	COG0488	(ABC) transporter
HZZ03_RS06495	COG3210	domain, Protein
HZZ03_RS06505	COG2271	Major facilitator Superfamily
HZZ03_RS06510	COG1609	Transcriptional regulator
HZZ03_RS06515	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HZZ03_RS06520	COG0303	'Molybdopterin
HZZ03_RS06530	COG0747	negative chemotaxis
HZZ03_RS06550	COG2133	pyrroloquinoline quinone binding
HZZ03_RS06555	COG0625	glutathione transferase activity
HZZ03_RS06560	COG1686	Belongs to the peptidase S11 family
HZZ03_RS06565	COG1349	DNA-binding transcription factor activity
HZZ03_RS06570	COG0671	phosphoesterase, PA-phosphatase related
HZZ03_RS06580	COG2814	Major facilitator Superfamily
HZZ03_RS06585	COG0561	phosphatase activity
HZZ03_RS06595	COG0738	Major facilitator superfamily
HZZ03_RS06600	COG3226	Transcriptional regulator
HZZ03_RS06635	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HZZ03_RS06640	COG3842	ATPase activity
HZZ03_RS06645	COG1176	ABC-type spermidine putrescine transport system, permease component I
HZZ03_RS06650	COG1177	transmembrane transport
HZZ03_RS06665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HZZ03_RS06670	COG4160	amino acid transport
HZZ03_RS06675	COG4215	(ABC) transporter
HZZ03_RS06680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HZZ03_RS06685	COG1126	abc transporter atp-binding protein
HZZ03_RS06700	COG3023	N-Acetylmuramoyl-L-alanine amidase
HZZ03_RS06705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HZZ03_RS06710	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HZZ03_RS06715	COG0028	Belongs to the TPP enzyme family
HZZ03_RS06720	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HZZ03_RS06730	COG2431	L-lysine efflux transmembrane transporter activity
HZZ03_RS06735	COG3593	DNA synthesis involved in DNA repair
HZZ03_RS06740	COG2990	Protein conserved in bacteria
HZZ03_RS06745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HZZ03_RS06755	COG1278	Cold shock
HZZ03_RS06765	COG0542	response to heat
HZZ03_RS06780	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HZZ03_RS06785	COG4988	ABC transporter
HZZ03_RS06790	COG0492	ferredoxin-NADP+ reductase activity
HZZ03_RS06810	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HZZ03_RS06820	COG0477	Major facilitator Superfamily
HZZ03_RS06825	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HZZ03_RS06830	COG1882	Formate acetyltransferase
HZZ03_RS06835	COG2116	formate transmembrane transporter activity
HZZ03_RS06840	COG1944	ATP diphosphatase activity
HZZ03_RS06845	COG2323	membrane
HZZ03_RS06860	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HZZ03_RS06865	COG0539	negative regulation of cytoplasmic translation
HZZ03_RS06875	COG2333	competence protein COMEC
HZZ03_RS06875	COG0658	competence protein
HZZ03_RS06890	COG3214	Protein conserved in bacteria
HZZ03_RS06905	COG1522	sequence-specific DNA binding
HZZ03_RS06915	COG3173	Aminoglycoside phosphotransferase
HZZ03_RS06920	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HZZ03_RS06925	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HZZ03_RS06935	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HZZ03_RS06945	COG2989	Protein conserved in bacteria
HZZ03_RS06950	COG3108	Peptidase M15
HZZ03_RS06955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HZZ03_RS06960	COG1448	Aminotransferase
HZZ03_RS06980	COG0308	aminopeptidase N
HZZ03_RS06985	COG1116	anion transmembrane transporter activity
HZZ03_RS06990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HZZ03_RS07000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HZZ03_RS07005	COG0431	NADPH-dependent FMN reductase
HZZ03_RS07020	COG3217	Mosc domain protein beta barrel domain protein
HZZ03_RS07020	COG0633	Ferredoxin
HZZ03_RS07030	COG0488	(ABC) transporter
HZZ03_RS07035	COG2995	paraquat-inducible protein a
HZZ03_RS07040	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HZZ03_RS07040	COG3008	intermembrane lipid transfer
HZZ03_RS07045	COG3009	Protein conserved in bacteria
HZZ03_RS07050	COG3130	regulation of translation
HZZ03_RS07060	COG1067	ATP-dependent peptidase activity
HZZ03_RS07080	COG3070	regulator of competence-specific genes
HZZ03_RS07085	COG1289	transmembrane transporter activity
HZZ03_RS07090	COG3304	Inner membrane component domain
HZZ03_RS07095	COG0210	DNA helicase
HZZ03_RS07105	COG1832	CoA-binding protein
HZZ03_RS07130	COG0670	Belongs to the BI1 family
HZZ03_RS07135	COG4166	transmembrane transport
HZZ03_RS07180	COG3729	General stress protein
HZZ03_RS07185	COG2233	PERMEase
HZZ03_RS07220	COG1309	transcriptional regulator
HZZ03_RS07235	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HZZ03_RS07235	COG0506	proline dehydrogenase activity
HZZ03_RS07235	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HZZ03_RS07240	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HZZ03_RS07250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HZZ03_RS07260	COG2822	iron ion transport
HZZ03_RS07270	COG1702	phosphate starvation-inducible protein PhoH
HZZ03_RS07280	COG0243	molybdopterin cofactor binding
HZZ03_RS07300	COG3121	Chaperone
HZZ03_RS07305	COG3188	usher protein
HZZ03_RS07325	COG3381	protein complex oligomerization
HZZ03_RS07345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HZZ03_RS07365	COG5645	(Lipo)protein
HZZ03_RS07375	COG1560	Kdo2-lipid A biosynthetic process
HZZ03_RS07390	COG3038	cytochrome b561
HZZ03_RS07420	COG2999	glutathione oxidoreductase activity
HZZ03_RS07430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HZZ03_RS07440	COG0673	inositol 2-dehydrogenase activity
HZZ03_RS07445	COG0728	peptidoglycan biosynthetic process
HZZ03_RS07465	COG1815	bacterial-type flagellum-dependent cell motility
HZZ03_RS07470	COG1558	bacterial-type flagellum-dependent cell motility
HZZ03_RS07475	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HZZ03_RS07490	COG4786	Flagellar basal body rod
HZZ03_RS07510	COG1256	bacterial-type flagellum assembly
HZZ03_RS07515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HZZ03_RS07520	COG2814	Major facilitator Superfamily
HZZ03_RS07530	COG1530	ribonuclease E activity
HZZ03_RS07535	COG0564	pseudouridine synthase activity
HZZ03_RS07545	COG0424	maF-like protein
HZZ03_RS07575	COG1028	Short-chain dehydrogenase reductase Sdr
HZZ03_RS07585	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HZZ03_RS07590	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HZZ03_RS07595	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HZZ03_RS07605	COG0470	DNA polymerase III
HZZ03_RS07610	COG0084	hydrolase, TatD family'
HZZ03_RS07615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZZ03_RS07615	COG1263	PTS System
HZZ03_RS07620	COG4773	Receptor
HZZ03_RS07625	COG0537	adenosine 5'-monophosphoramidase activity
HZZ03_RS07630	COG5633	Lipoprotein
HZZ03_RS07640	COG0510	thiamine kinase activity
HZZ03_RS07655	COG1252	NADH dehydrogenase
HZZ03_RS07660	COG3134	Outer membrane lipoprotein
HZZ03_RS07665	COG1309	transcriptional regulator
HZZ03_RS07675	COG1388	LysM domain
HZZ03_RS07675	COG1376	ErfK ybiS ycfS ynhG family protein
HZZ03_RS07680	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HZZ03_RS07685	COG4591	ABC-type transport system involved in lipoprotein release permease component
HZZ03_RS07695	COG4591	ABC-type transport system involved in lipoprotein release permease component
HZZ03_RS07710	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HZZ03_RS07715	COG1177	transmembrane transport
HZZ03_RS07735	COG2850	peptidyl-arginine hydroxylation
HZZ03_RS07740	COG2205	protein histidine kinase activity
HZZ03_RS07750	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HZZ03_RS07765	COG0840	transmembrane signaling receptor activity
HZZ03_RS07775	COG1187	pseudouridine synthase activity
HZZ03_RS07780	COG0538	isocitrate dehydrogenase activity
HZZ03_RS07800	COG0583	DNA-binding transcription factor activity
HZZ03_RS07820	COG0840	transmembrane signaling receptor activity
HZZ03_RS07835	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HZZ03_RS07840	COG1278	Cold shock
HZZ03_RS07860	COG0835	chemotaxis
HZZ03_RS07860	COG0784	Response regulator, receiver
HZZ03_RS07875	COG2990	Protein conserved in bacteria
HZZ03_RS07885	COG3189	MarR family transcriptional regulator
HZZ03_RS07890	COG0504	CTP synthase activity
HZZ03_RS07895	COG2807	transmembrane transport
HZZ03_RS07905	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HZZ03_RS07910	COG3729	General stress protein
HZZ03_RS07915	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HZZ03_RS07920	COG2718	Belongs to the UPF0229 family
HZZ03_RS07925	COG2766	serine protein kinase
HZZ03_RS07930	COG3713	MltA-interacting MipA family protein
HZZ03_RS07940	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HZZ03_RS07950	COG3139	Protein of unknown function (DUF1315)
HZZ03_RS07955	COG1335	isochorismatase
HZZ03_RS07960	COG0252	asparaginase activity
HZZ03_RS07965	COG0616	signal peptide processing
HZZ03_RS07970	COG0778	Nitroreductase
HZZ03_RS07980	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HZZ03_RS07990	COG0494	nUDIX hydrolase
HZZ03_RS07995	COG0708	Exodeoxyribonuclease III
HZZ03_RS08025	COG3678	ATP-independent chaperone mediated protein folding
HZZ03_RS08035	COG0322	excinuclease ABC activity
HZZ03_RS08050	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HZZ03_RS08055	COG0753	catalase activity
HZZ03_RS08070	COG3093	addiction module antidote protein HigA
HZZ03_RS08080	COG1988	membrane-bound metal-dependent
HZZ03_RS08085	COG1028	Short-chain dehydrogenase reductase Sdr
HZZ03_RS08090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HZZ03_RS08100	COG3001	Fructosamine kinase
HZZ03_RS08110	COG1105	Belongs to the carbohydrate kinase PfkB family
HZZ03_RS08115	COG3137	Salt-induced outer membrane protein
HZZ03_RS08155	COG0456	acetyltransferase
HZZ03_RS08200	COG4139	cobalamin transport
HZZ03_RS08205	COG0386	Belongs to the glutathione peroxidase family
HZZ03_RS08215	COG0791	NLP P60 protein
HZZ03_RS08220	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HZZ03_RS08225	COG1486	melibiose metabolic process
HZZ03_RS08230	COG1609	Transcriptional regulator
HZZ03_RS08245	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HZZ03_RS08255	COG0574	Belongs to the PEP-utilizing enzyme family
HZZ03_RS08255	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HZZ03_RS08260	COG2211	Major facilitator Superfamily
HZZ03_RS08265	COG1472	Belongs to the glycosyl hydrolase 3 family
HZZ03_RS08275	COG0628	permease
HZZ03_RS08280	COG0247	lactate metabolic process
HZZ03_RS08280	COG0277	FAD linked oxidase domain protein
HZZ03_RS08285	COG2050	protein possibly involved in aromatic compounds catabolism
HZZ03_RS08295	COG0316	Belongs to the HesB IscA family
HZZ03_RS08300	COG0719	Fe-S assembly protein
HZZ03_RS08305	COG0396	ATPase activity
HZZ03_RS08310	COG0719	Fe-S assembly protein
HZZ03_RS08345	COG3468	outer membrane autotransporter barrel domain protein
HZZ03_RS08345	COG3468	outer membrane autotransporter barrel domain protein
HZZ03_RS08350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HZZ03_RS08355	COG1012	belongs to the aldehyde dehydrogenase family
HZZ03_RS08360	COG1396	sequence-specific DNA binding
HZZ03_RS08360	COG1917	Cupin 2, conserved barrel domain protein
HZZ03_RS08365	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HZZ03_RS08370	COG0174	glutamine synthetase
HZZ03_RS08375	COG0531	amino acid
HZZ03_RS08380	COG3604	Transcriptional regulator
HZZ03_RS08385	COG0309	Hydrogenase expression formation protein (HypE)
HZZ03_RS08390	COG0409	Hydrogenase expression formation protein
HZZ03_RS08395	COG0298	carbon dioxide binding
HZZ03_RS08400	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HZZ03_RS08405	COG0375	protein maturation
HZZ03_RS08415	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HZZ03_RS08420	COG0651	ATP synthesis coupled electron transport
HZZ03_RS08425	COG0650	Formate hydrogenlyase subunit 4
HZZ03_RS08430	COG3261	NADH dehydrogenase
HZZ03_RS08430	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HZZ03_RS08435	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HZZ03_RS08440	COG3260	NADH ubiquinone oxidoreductase 20
HZZ03_RS08450	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HZZ03_RS08460	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HZZ03_RS08465	COG3383	formate dehydrogenase (NAD+) activity
HZZ03_RS08470	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HZZ03_RS08475	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HZZ03_RS08485	COG0583	DNA-binding transcription factor activity
HZZ03_RS08490	COG2814	Major facilitator Superfamily
HZZ03_RS08525	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HZZ03_RS08630	COG0307	riboflavin synthase, alpha
HZZ03_RS08640	COG2723	6-phospho-beta-galactosidase activity
HZZ03_RS08645	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HZZ03_RS08650	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HZZ03_RS08655	COG2814	Major facilitator Superfamily
HZZ03_RS08660	COG0583	DNA-binding transcription factor activity
HZZ03_RS08675	COG2814	Major facilitator Superfamily
HZZ03_RS08680	COG0791	NLP P60 protein
HZZ03_RS08685	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HZZ03_RS08695	COG0346	lactoylglutathione lyase activity
HZZ03_RS08700	COG1902	pentaerythritol trinitrate reductase activity
HZZ03_RS08705	COG1309	transcriptional regulator
HZZ03_RS08715	COG3313	Fe-S protein
HZZ03_RS08720	COG4989	oxidoreductase activity
HZZ03_RS08725	COG2032	superoxide dismutase activity
HZZ03_RS08730	COG1289	transmembrane transporter activity
HZZ03_RS08735	COG1566	PFAM secretion protein HlyD family protein
HZZ03_RS08775	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HZZ03_RS08780	COG0625	glutathione transferase activity
HZZ03_RS08790	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HZZ03_RS08840	COG0673	inositol 2-dehydrogenase activity
HZZ03_RS08845	COG0385	Bile acid
HZZ03_RS08850	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HZZ03_RS08855	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HZZ03_RS08860	COG1263	PTS System
HZZ03_RS08860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZZ03_RS08865	COG1609	Transcriptional regulator
HZZ03_RS08870	COG3539	Fimbrial protein
HZZ03_RS08875	COG3121	Chaperone
HZZ03_RS08890	COG3539	Fimbrial protein
HZZ03_RS08895	COG3539	Fimbrial protein
HZZ03_RS08905	COG5339	Protein conserved in bacteria
HZZ03_RS08920	COG0114	fumarate hydratase activity
HZZ03_RS08930	COG2205	protein histidine kinase activity
HZZ03_RS08940	COG1028	Short-chain dehydrogenase reductase Sdr
HZZ03_RS08945	COG0745	RESPONSE REGULATOR receiver
HZZ03_RS08955	COG0531	amino acid
HZZ03_RS08965	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HZZ03_RS08970	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HZZ03_RS08975	COG0589	response to stress
HZZ03_RS08980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HZZ03_RS08985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HZZ03_RS08990	COG2840	Smr protein MutS2
HZZ03_RS08995	COG0561	phosphatase activity
HZZ03_RS09005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HZZ03_RS09010	COG4172	Belongs to the ABC transporter superfamily
HZZ03_RS09020	COG0601	transmembrane transport
HZZ03_RS09025	COG0747	negative chemotaxis
HZZ03_RS09040	COG2211	Major facilitator Superfamily
HZZ03_RS09045	COG2076	Multidrug Resistance protein
HZZ03_RS09060	COG1294	oxidase, subunit
HZZ03_RS09065	COG1271	oxidase subunit
HZZ03_RS09070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HZZ03_RS09075	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HZZ03_RS09080	COG3842	ATPase activity
HZZ03_RS09085	COG1176	ABC-type spermidine putrescine transport system, permease component I
HZZ03_RS09090	COG1177	transmembrane transport
HZZ03_RS09095	COG1012	belongs to the aldehyde dehydrogenase family
HZZ03_RS09125	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HZZ03_RS09135	COG0243	molybdopterin cofactor binding
HZZ03_RS09140	COG0437	4 iron, 4 sulfur cluster binding
HZZ03_RS09145	COG3302	dmso reductase anchor subunit
HZZ03_RS09150	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HZZ03_RS09160	COG0840	transmembrane signaling receptor activity
HZZ03_RS09190	COG0747	negative chemotaxis
HZZ03_RS09200	COG2084	Dehydrogenase
HZZ03_RS09205	COG3238	Protein conserved in bacteria
HZZ03_RS09210	COG1247	-acetyltransferase
HZZ03_RS09220	COG2130	NADP-dependent
HZZ03_RS09240	COG0601	transmembrane transport
HZZ03_RS09255	COG1802	Transcriptional regulator
HZZ03_RS09265	COG0840	transmembrane signaling receptor activity
HZZ03_RS09270	COG4221	oxidoreductase activity
HZZ03_RS09285	COG3093	addiction module antidote protein HigA
HZZ03_RS09290	COG4772	TonB-dependent receptor
HZZ03_RS09300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HZZ03_RS09305	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HZZ03_RS09310	COG2175	clavaminate synthase activity
HZZ03_RS09335	COG0778	Nitroreductase
HZZ03_RS09345	COG3546	catalase activity
HZZ03_RS09350	COG3685	Protein conserved in bacteria
HZZ03_RS09355	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HZZ03_RS09370	COG1064	alcohol dehydrogenase
HZZ03_RS09375	COG1028	Short-chain dehydrogenase reductase Sdr
HZZ03_RS09400	COG4221	oxidoreductase activity
HZZ03_RS09405	COG2207	Transcriptional regulator
HZZ03_RS09425	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HZZ03_RS09445	COG0791	NLP P60 protein
HZZ03_RS09450	COG0789	Transcriptional regulator
HZZ03_RS09455	COG0596	Alpha beta hydrolase
HZZ03_RS09475	COG0456	acetyltransferase
HZZ03_RS09475	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HZZ03_RS09525	COG0784	Response regulator, receiver
HZZ03_RS09525	COG2205	protein histidine kinase activity
HZZ03_RS09525	COG5002	protein histidine kinase activity
HZZ03_RS09530	COG3250	beta-galactosidase activity
HZZ03_RS09555	COG3447	MASE1 domain protein
HZZ03_RS09555	COG5002	protein histidine kinase activity
HZZ03_RS09555	COG5001	Diguanylate cyclase
HZZ03_RS09565	COG2199	diguanylate cyclase activity
HZZ03_RS09580	COG0840	transmembrane signaling receptor activity
HZZ03_RS09585	COG1012	belongs to the aldehyde dehydrogenase family
HZZ03_RS09590	COG0583	DNA-binding transcription factor activity
HZZ03_RS09600	COG0039	L-malate dehydrogenase activity
HZZ03_RS09610	COG2814	Major facilitator Superfamily
HZZ03_RS09615	COG1846	Transcriptional regulator
HZZ03_RS09620	COG4977	sequence-specific DNA binding
HZZ03_RS09630	COG0697	spore germination
HZZ03_RS09635	COG2814	Major facilitator Superfamily
HZZ03_RS09695	COG1358	cellular component organization or biogenesis
HZZ03_RS09725	COG4245	von Willebrand factor, type A
HZZ03_RS09730	COG4245	von Willebrand factor, type A
HZZ03_RS09810	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HZZ03_RS09820	COG3729	General stress protein
HZZ03_RS09830	COG3781	membrane
HZZ03_RS09845	COG0339	signal peptide processing
HZZ03_RS09850	COG4221	oxidoreductase activity
HZZ03_RS09855	COG1802	Transcriptional regulator
HZZ03_RS09870	COG0246	Mannitol dehydrogenase
HZZ03_RS09875	COG2271	Major facilitator Superfamily
HZZ03_RS09880	COG4948	Mandelate Racemase Muconate Lactonizing
HZZ03_RS09895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HZZ03_RS09910	COG0243	molybdopterin cofactor binding
HZZ03_RS09915	COG0437	4 iron, 4 sulfur cluster binding
HZZ03_RS09920	COG3302	dmso reductase anchor subunit
HZZ03_RS09925	COG3381	protein complex oligomerization
HZZ03_RS09930	COG3136	membrane protein required for alginate biosynthesis
HZZ03_RS09955	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HZZ03_RS09960	COG1940	carbohydrate kinase activity
HZZ03_RS09965	COG0583	DNA-binding transcription factor activity
HZZ03_RS09970	COG2814	Major facilitator Superfamily
HZZ03_RS09975	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HZZ03_RS09980	COG3591	Belongs to the peptidase S1B family
HZZ03_RS10010	COG0826	peptidase U32
HZZ03_RS10015	COG1396	sequence-specific DNA binding
HZZ03_RS10020	COG3135	benzoate transporter
HZZ03_RS10035	COG3179	chitinase
HZZ03_RS10050	COG2246	polysaccharide biosynthetic process
HZZ03_RS10055	COG0463	Glycosyl transferase, family 2
HZZ03_RS10235	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HZZ03_RS10280	COG0500	methyltransferase
HZZ03_RS10285	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HZZ03_RS10290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HZZ03_RS10305	COG5383	Protein conserved in bacteria
HZZ03_RS10315	COG0583	DNA-binding transcription factor activity
HZZ03_RS10320	COG1902	pentaerythritol trinitrate reductase activity
HZZ03_RS10325	COG3685	Protein conserved in bacteria
HZZ03_RS10330	COG0840	transmembrane signaling receptor activity
HZZ03_RS10350	COG0477	Major facilitator Superfamily
HZZ03_RS10355	COG3038	cytochrome b561
HZZ03_RS10360	COG2755	lipolytic protein G-D-S-L family
HZZ03_RS10360	COG0657	acetylesterase activity
HZZ03_RS10365	COG1012	belongs to the aldehyde dehydrogenase family
HZZ03_RS10370	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HZZ03_RS10400	COG1538	Outer membrane efflux protein
HZZ03_RS10405	COG4122	O-methyltransferase activity
HZZ03_RS10410	COG1943	Transposase
HZZ03_RS10415	COG1643	Atp-dependent helicase
HZZ03_RS10430	COG3784	Protein of unknown function (DUF1318)
HZZ03_RS10440	COG2911	Protein conserved in bacteria
HZZ03_RS10445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HZZ03_RS10450	COG3187	Heat shock protein
HZZ03_RS10455	COG3042	response to heat
HZZ03_RS10460	COG1013	pyruvate-flavodoxin oxidoreductase activity
HZZ03_RS10460	COG0674	pyruvate-flavodoxin oxidoreductase activity
HZZ03_RS10460	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HZZ03_RS10460	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HZZ03_RS10475	COG1012	belongs to the aldehyde dehydrogenase family
HZZ03_RS10480	COG3284	Transcriptional regulator
HZZ03_RS10490	COG1028	Short-chain dehydrogenase reductase Sdr
HZZ03_RS10535	COG3300	MHYT domain
HZZ03_RS10535	COG5001	Diguanylate cyclase
HZZ03_RS10540	COG3729	General stress protein
HZZ03_RS10565	COG4166	transmembrane transport
HZZ03_RS10570	COG2866	Carboxypeptidase
HZZ03_RS10575	COG4948	Mandelate Racemase Muconate Lactonizing
HZZ03_RS10595	COG3106	COG3106 Predicted ATPase
HZZ03_RS10600	COG1609	Transcriptional regulator
HZZ03_RS10610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HZZ03_RS10615	COG1554	hydrolase, family 65, central catalytic
HZZ03_RS10620	COG0673	inositol 2-dehydrogenase activity
HZZ03_RS10645	COG3778	Protein conserved in bacteria
HZZ03_RS10650	COG3299	homolog of phage Mu protein gp47
HZZ03_RS10690	COG4386	tail sheath protein
HZZ03_RS10740	COG4626	Terminase
HZZ03_RS10740	COG1802	Transcriptional regulator
HZZ03_RS10775	COG3772	lysozyme
HZZ03_RS10820	COG1846	Transcriptional regulator
HZZ03_RS10835	COG1396	sequence-specific DNA binding
HZZ03_RS10855	COG0582	viral genome integration into host DNA
HZZ03_RS10860	COG1082	Xylose isomerase domain protein TIM barrel
HZZ03_RS10865	COG1063	alcohol dehydrogenase
HZZ03_RS10870	COG0395	ABC-type sugar transport system, permease component
HZZ03_RS10875	COG1175	transmembrane transport
HZZ03_RS10880	COG1653	transport
HZZ03_RS10885	COG0366	Alpha amylase catalytic
HZZ03_RS10895	COG1983	PspC domain protein
HZZ03_RS10905	COG1842	Phage shock protein A
HZZ03_RS10910	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HZZ03_RS10925	COG4171	peptide transport system, permease
HZZ03_RS10935	COG4172	Belongs to the ABC transporter superfamily
HZZ03_RS10945	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HZZ03_RS10945	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HZZ03_RS10955	COG5001	Diguanylate cyclase
HZZ03_RS10960	COG1024	Enoyl-CoA hydratase
HZZ03_RS10975	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HZZ03_RS10980	COG1882	Formate acetyltransferase
HZZ03_RS10985	COG1349	DNA-binding transcription factor activity
HZZ03_RS10995	COG0023	Translation Initiation Factor
HZZ03_RS11005	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HZZ03_RS11010	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HZZ03_RS11015	COG0671	phosphoesterase, PA-phosphatase related
HZZ03_RS11050	COG0616	signal peptide processing
HZZ03_RS11055	COG1028	Short-chain dehydrogenase reductase Sdr
HZZ03_RS11060	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HZZ03_RS11070	COG0009	L-threonylcarbamoyladenylate synthase
HZZ03_RS11075	COG0613	PHP domain protein
HZZ03_RS11090	COG0512	Glutamine amidotransferase of anthranilate synthase
HZZ03_RS11090	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HZZ03_RS11115	COG3047	cAMP biosynthetic process
HZZ03_RS11120	COG0727	PFAM Uncharacterised protein family (UPF0153)
HZZ03_RS11150	COG2350	Protein conserved in bacteria
HZZ03_RS11175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HZZ03_RS11185	COG0444	Belongs to the ABC transporter superfamily
HZZ03_RS11190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HZZ03_RS11195	COG0601	transmembrane transport
HZZ03_RS11205	COG2095	MarC family integral membrane protein
HZZ03_RS11210	COG1012	belongs to the aldehyde dehydrogenase family
HZZ03_RS11210	COG1454	alcohol dehydrogenase
HZZ03_RS11235	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HZZ03_RS11240	COG0745	RESPONSE REGULATOR receiver
HZZ03_RS11250	COG0788	formyltetrahydrofolate deformylase activity
HZZ03_RS11275	COG1028	Short-chain dehydrogenase reductase Sdr
HZZ03_RS11285	COG2181	nitrate reductase activity
HZZ03_RS11290	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HZZ03_RS11295	COG1140	nitrate reductase beta subunit
HZZ03_RS11300	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HZZ03_RS11305	COG2223	nitrite transmembrane transporter activity
HZZ03_RS11310	COG3850	Histidine kinase
HZZ03_RS11315	COG2197	response regulator
HZZ03_RS11320	COG4932	domain protein
HZZ03_RS11330	COG0243	molybdopterin cofactor binding
HZZ03_RS11335	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HZZ03_RS11335	COG2146	nitrite reductase [NAD(P)H] activity
HZZ03_RS11340	COG1116	anion transmembrane transporter activity
HZZ03_RS11345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HZZ03_RS11350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HZZ03_RS11355	COG3707	response regulator
HZZ03_RS11360	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HZZ03_RS11365	COG0840	transmembrane signaling receptor activity
HZZ03_RS11375	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HZZ03_RS11380	COG4572	Cation transport regulator
HZZ03_RS11385	COG0387	Pfam Sodium calcium exchanger
HZZ03_RS11405	COG2890	protein-(glutamine-N5) methyltransferase activity
HZZ03_RS11435	COG0659	secondary active sulfate transmembrane transporter activity
HZZ03_RS11455	COG0012	GTP binding
HZZ03_RS11460	COG3318	Belongs to the UPF0149 family
HZZ03_RS11460	COG3012	SEC-C Motif Domain Protein
HZZ03_RS11475	COG2249	NAD(P)H dehydrogenase (quinone) activity
HZZ03_RS11485	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HZZ03_RS11500	COG4774	siderophore transport
HZZ03_RS11520	COG1619	proteins homologs of microcin C7 resistance protein MccF
HZZ03_RS11540	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HZZ03_RS11550	COG2719	SpoVR family
HZZ03_RS11580	COG0179	Fumarylacetoacetate (FAA) hydrolase
HZZ03_RS11595	COG2894	cell division
HZZ03_RS11610	COG0318	PFAM AMP-dependent synthetase and ligase
HZZ03_RS11615	COG3065	identical protein binding
HZZ03_RS11620	COG1214	PFAM Peptidase M22, glycoprotease
HZZ03_RS11625	COG1199	ATP-dependent helicase activity
HZZ03_RS11630	COG0251	oxidation-reduction process
HZZ03_RS11635	COG3239	Fatty acid desaturase
HZZ03_RS11665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HZZ03_RS11670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HZZ03_RS11690	COG1760	l-serine dehydratase
HZZ03_RS11695	COG2200	EAL domain
HZZ03_RS11700	COG1253	flavin adenine dinucleotide binding
HZZ03_RS11705	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HZZ03_RS11705	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZZ03_RS11710	COG3715	PTS system
HZZ03_RS11715	COG3716	PTS system mannose fructose sorbose family IID component
HZZ03_RS11730	COG2226	methyltransferase
HZZ03_RS11765	COG1414	Transcriptional regulator
HZZ03_RS11785	COG1956	GAF domain-containing protein
HZZ03_RS11790	COG2995	paraquat-inducible protein a
HZZ03_RS11795	COG3008	intermembrane lipid transfer
HZZ03_RS11835	COG1276	copper resistance
HZZ03_RS11840	COG2372	response to copper ion
HZZ03_RS11850	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HZZ03_RS11855	COG1770	oligopeptidase
HZZ03_RS11860	COG2979	Protein of unknown function (DUF533)
HZZ03_RS11870	COG3141	response to X-ray
HZZ03_RS11880	COG0800	Aldolase
HZZ03_RS11885	COG0129	dihydroxy-acid dehydratase activity
HZZ03_RS11890	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HZZ03_RS11895	COG1737	Transcriptional regulator
HZZ03_RS11900	COG0469	pyruvate kinase activity
HZZ03_RS11905	COG1560	Kdo2-lipid A biosynthetic process
HZZ03_RS11910	COG0739	heme binding
HZZ03_RS11915	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HZZ03_RS11925	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HZZ03_RS11950	COG0494	nUDIX hydrolase
HZZ03_RS11960	COG1335	isochorismatase
HZZ03_RS11965	COG1801	Protein of unknown function DUF72
HZZ03_RS11970	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HZZ03_RS11985	COG1652	LysM domain
HZZ03_RS11990	COG2214	Heat shock protein DnaJ domain protein
HZZ03_RS11995	COG0443	Heat shock 70 kDa protein
HZZ03_RS12000	COG3142	Participates in the control of copper homeostasis
HZZ03_RS12005	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HZZ03_RS12020	COG3102	Protein conserved in bacteria
HZZ03_RS12035	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HZZ03_RS12065	COG0745	RESPONSE REGULATOR receiver
HZZ03_RS12110	COG0835	chemotaxis
HZZ03_RS12140	COG0589	response to stress
HZZ03_RS12155	COG1172	Belongs to the binding-protein-dependent transport system permease family
HZZ03_RS12165	COG1879	ABC-type sugar transport system periplasmic component
HZZ03_RS12170	COG4297	protein containing double-stranded beta helix domain
HZZ03_RS12175	COG1528	Iron-storage protein
HZZ03_RS12180	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HZZ03_RS12205	COG0477	Major facilitator Superfamily
HZZ03_RS12225	COG1528	Iron-storage protein
HZZ03_RS12230	COG0814	amino acid
HZZ03_RS12265	COG2197	response regulator
HZZ03_RS12275	COG2197	response regulator
HZZ03_RS12320	COG0318	PFAM AMP-dependent synthetase and ligase
HZZ03_RS12330	COG1028	Short-chain dehydrogenase reductase Sdr
HZZ03_RS12335	COG1028	Short-chain dehydrogenase reductase Sdr
HZZ03_RS12395	COG0425	Belongs to the sulfur carrier protein TusA family
HZZ03_RS12400	COG2135	peptidase activity
HZZ03_RS12405	COG2226	methyltransferase
HZZ03_RS12410	COG0583	DNA-binding transcription factor activity
HZZ03_RS12415	COG2814	Major facilitator Superfamily
HZZ03_RS12425	COG0702	epimerase
HZZ03_RS12440	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
HZZ03_RS12460	COG0582	viral genome integration into host DNA
HZZ03_RS12505	COG0431	NADPH-dependent FMN reductase
HZZ03_RS12510	COG1393	Belongs to the ArsC family
HZZ03_RS12515	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HZZ03_RS12525	COG0789	Transcriptional regulator
HZZ03_RS12545	COG4974	Belongs to the 'phage' integrase family
HZZ03_RS12570	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HZZ03_RS12575	COG1317	bacterial-type flagellum organization
HZZ03_RS12580	COG1157	protein secretion by the type III secretion system
HZZ03_RS12595	COG1580	Controls the rotational direction of flagella during chemotaxis
HZZ03_RS12630	COG2197	response regulator
HZZ03_RS12655	COG5475	Uncharacterized small protein (DUF2158)
HZZ03_RS12660	COG2354	Protein conserved in bacteria
HZZ03_RS12665	COG0697	spore germination
HZZ03_RS12670	COG3727	T/G mismatch-specific endonuclease activity
HZZ03_RS12675	COG0270	DNA (cytosine-5-)-methyltransferase activity
HZZ03_RS12680	COG1418	mRNA catabolic process
HZZ03_RS12685	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HZZ03_RS12695	COG1028	Short-chain dehydrogenase reductase Sdr
HZZ03_RS12705	COG0583	DNA-binding transcription factor activity
HZZ03_RS12710	COG4251	negative regulation of phosphorylation
HZZ03_RS12710	COG5001	Diguanylate cyclase
HZZ03_RS12710	COG3706	GGDEF domain
HZZ03_RS12710	COG2203	Gaf domain
HZZ03_RS12730	COG0477	Major facilitator Superfamily
HZZ03_RS12750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HZZ03_RS12755	COG2200	EAL domain
HZZ03_RS12760	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HZZ03_RS12785	COG3501	Rhs element vgr protein
HZZ03_RS12790	COG0534	Mate efflux family protein
HZZ03_RS12805	COG1289	transmembrane transporter activity
HZZ03_RS12825	COG2925	Exonuclease
HZZ03_RS12830	COG0531	amino acid
HZZ03_RS12840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HZZ03_RS12845	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HZZ03_RS12850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HZZ03_RS12860	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HZZ03_RS12865	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HZZ03_RS12905	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HZZ03_RS12910	COG1215	transferase activity, transferring glycosyl groups
HZZ03_RS12925	COG1215	transferase activity, transferring glycosyl groups
HZZ03_RS12930	COG2244	polysaccharide biosynthetic process
HZZ03_RS12970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HZZ03_RS12980	COG0438	transferase activity, transferring glycosyl groups
HZZ03_RS12985	COG2327	Polysaccharide pyruvyl transferase
HZZ03_RS12990	COG2244	polysaccharide biosynthetic process
HZZ03_RS12995	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HZZ03_RS13000	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HZZ03_RS13005	COG0662	Cupin 2, conserved barrel domain protein
HZZ03_RS13005	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
HZZ03_RS13010	COG0297	glycogen (starch) synthase activity
HZZ03_RS13015	COG1051	belongs to the nudix hydrolase family
HZZ03_RS13020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HZZ03_RS13025	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HZZ03_RS13030	COG0110	maltose O-acetyltransferase activity
HZZ03_RS13035	COG1216	Glycosyl transferase, family 2
HZZ03_RS13045	COG0438	transferase activity, transferring glycosyl groups
HZZ03_RS13050	COG1045	serine acetyltransferase
HZZ03_RS13055	COG0463	Glycosyl transferase, family 2
HZZ03_RS13075	COG1253	flavin adenine dinucleotide binding
HZZ03_RS13080	COG2982	Protein involved in outer membrane biogenesis
HZZ03_RS13095	COG5001	Diguanylate cyclase
HZZ03_RS13095	COG5002	protein histidine kinase activity
HZZ03_RS13095	COG3447	MASE1 domain protein
HZZ03_RS13100	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HZZ03_RS13105	COG0443	Heat shock 70 kDa protein
HZZ03_RS13115	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
HZZ03_RS13140	COG2205	protein histidine kinase activity
HZZ03_RS13145	COG0745	RESPONSE REGULATOR receiver
HZZ03_RS13160	COG1830	Aldolase
HZZ03_RS13165	COG0351	phosphomethylpyrimidine kinase
HZZ03_RS13185	COG5455	response to cobalt ion
HZZ03_RS13190	COG0488	(ABC) transporter
HZZ03_RS13205	COG0840	transmembrane signaling receptor activity
HZZ03_RS13215	COG3275	phosphorelay sensor kinase activity
HZZ03_RS13225	COG0489	protein tyrosine kinase activity
HZZ03_RS13245	COG1136	(ABC) transporter
HZZ03_RS13250	COG0577	efflux transmembrane transporter activity
HZZ03_RS13250	COG1136	(ABC) transporter
HZZ03_RS13260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HZZ03_RS13270	COG0789	Transcriptional regulator
HZZ03_RS13280	COG1174	glycine betaine transport
HZZ03_RS13285	COG1125	glycine betaine transport
HZZ03_RS13290	COG1174	glycine betaine transport
HZZ03_RS13295	COG1732	Glycine betaine
HZZ03_RS13300	COG1472	Belongs to the glycosyl hydrolase 3 family
HZZ03_RS13305	COG0277	FAD linked oxidase domain protein
HZZ03_RS13315	COG1686	Belongs to the peptidase S11 family
HZZ03_RS13325	COG0586	Pfam SNARE associated Golgi protein
HZZ03_RS13330	COG1028	Short-chain dehydrogenase reductase Sdr
HZZ03_RS13350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HZZ03_RS13370	COG1346	cytolysis
HZZ03_RS13380	COG2949	membrane
HZZ03_RS13390	COG1129	ABC transporter
HZZ03_RS13395	COG1879	ABC-type sugar transport system periplasmic component
HZZ03_RS13405	COG2311	Membrane
HZZ03_RS13410	COG0302	gtp cyclohydrolase
HZZ03_RS13415	COG0477	Major facilitator Superfamily
HZZ03_RS13425	COG0833	amino acid
HZZ03_RS13430	COG0583	DNA-binding transcription factor activity
HZZ03_RS13435	COG2855	membrane
HZZ03_RS13450	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HZZ03_RS13450	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HZZ03_RS13450	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HZZ03_RS13455	COG1105	Belongs to the carbohydrate kinase PfkB family
HZZ03_RS13460	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HZZ03_RS13460	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HZZ03_RS13490	COG0246	Mannitol dehydrogenase
HZZ03_RS13495	COG0523	cobalamin synthesis protein
HZZ03_RS13500	COG0671	phosphoesterase, PA-phosphatase related
HZZ03_RS13505	COG0791	NLP P60 protein
HZZ03_RS13510	COG2200	EAL domain
HZZ03_RS13515	COG4166	transmembrane transport
HZZ03_RS13520	COG4174	ABC transporter (Permease)
HZZ03_RS13525	COG4239	(ABC) transporter, permease
HZZ03_RS13530	COG4172	Belongs to the ABC transporter superfamily
HZZ03_RS13545	COG2814	Major facilitator Superfamily
HZZ03_RS13550	COG1187	pseudouridine synthase activity
HZZ03_RS13555	COG1061	Type III restriction enzyme res subunit
HZZ03_RS13575	COG3083	sulfuric ester hydrolase activity
HZZ03_RS13620	COG3121	Chaperone
HZZ03_RS13630	COG0659	secondary active sulfate transmembrane transporter activity
HZZ03_RS13635	COG4615	Cyclic peptide transporter
HZZ03_RS13640	COG3145	DNA-N1-methyladenine dioxygenase activity
HZZ03_RS13645	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HZZ03_RS13645	COG2169	Transcriptional regulator
HZZ03_RS13650	COG1477	protein flavinylation
HZZ03_RS13660	COG0642	Histidine kinase
HZZ03_RS13660	COG2198	Histidine kinase
HZZ03_RS13665	COG2197	response regulator
HZZ03_RS13685	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HZZ03_RS13695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HZZ03_RS13700	COG0584	glycerophosphoryl diester phosphodiesterase
HZZ03_RS13705	COG2271	Major facilitator Superfamily
HZZ03_RS13720	COG0642	Histidine kinase
HZZ03_RS13745	COG3647	Membrane
HZZ03_RS13775	COG1169	isochorismate synthase
HZZ03_RS13780	COG4575	ribosome binding
HZZ03_RS13785	COG2153	protein acetylation
HZZ03_RS13800	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HZZ03_RS13805	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HZZ03_RS13815	COG0839	Belongs to the complex I subunit 6 family
HZZ03_RS13835	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HZZ03_RS13860	COG0583	DNA-binding transcription factor activity
HZZ03_RS13865	COG0436	Aminotransferase
HZZ03_RS13875	COG0471	metal ion transport
HZZ03_RS13875	COG0490	domain, Protein
HZZ03_RS13880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HZZ03_RS13915	COG1309	transcriptional regulator
HZZ03_RS13925	COG0622	Phosphoesterase
HZZ03_RS13930	COG0625	glutathione transferase activity
HZZ03_RS13935	COG0625	glutathione transferase activity
HZZ03_RS13940	COG1090	epimerase
HZZ03_RS13955	COG4598	ABC transporter
HZZ03_RS13960	COG4160	amino acid transport
HZZ03_RS13970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HZZ03_RS13975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HZZ03_RS13980	COG0163	prenyltransferase activity
HZZ03_RS13985	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HZZ03_RS13990	COG1286	toxin biosynthetic process
HZZ03_RS13995	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HZZ03_RS14000	COG0285	dihydrofolate synthase activity
HZZ03_RS14010	COG0586	Pfam SNARE associated Golgi protein
HZZ03_RS14020	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HZZ03_RS14040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HZZ03_RS14055	COG3101	peptidyl-lysine hydroxylation
HZZ03_RS14060	COG0730	response to heat
HZZ03_RS14085	COG2062	phosphohistidine phosphatase, SixA
HZZ03_RS14100	COG3691	Protein conserved in bacteria
HZZ03_RS14105	COG2067	long-chain fatty acid transport protein
HZZ03_RS14115	COG3088	subunit of a heme lyase
HZZ03_RS14115	COG4235	cytochrome complex assembly
HZZ03_RS14120	COG3088	subunit of a heme lyase
HZZ03_RS14120	COG4235	cytochrome complex assembly
HZZ03_RS14130	COG1138	Cytochrome C-type biogenesis protein
HZZ03_RS14140	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HZZ03_RS14145	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HZZ03_RS14150	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HZZ03_RS14155	COG4133	protoheme IX ABC transporter activity
HZZ03_RS14160	COG2116	formate transmembrane transporter activity
HZZ03_RS14200	COG0598	Magnesium transport protein CorA
HZZ03_RS14215	COG0436	Aminotransferase
HZZ03_RS14225	COG3275	phosphorelay sensor kinase activity
HZZ03_RS14230	COG3279	Response regulator of the LytR AlgR family
HZZ03_RS14240	COG3961	Belongs to the TPP enzyme family
HZZ03_RS14245	COG0667	Aldo Keto reductase
HZZ03_RS14260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HZZ03_RS14265	COG2199	diguanylate cyclase activity
HZZ03_RS14265	COG2200	EAL domain
HZZ03_RS14280	COG3415	Transposase
HZZ03_RS14320	COG3530	Putative quorum-sensing-regulated virulence factor
HZZ03_RS14345	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HZZ03_RS14365	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HZZ03_RS14370	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HZZ03_RS14375	COG4208	sulfate ABC transporter
HZZ03_RS14380	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HZZ03_RS14385	COG4150	thiosulfate binding
HZZ03_RS14390	COG2837	iron assimilation
HZZ03_RS14405	COG3111	PFAM Bacterial OB fold (BOF) protein
HZZ03_RS14415	COG0860	N-Acetylmuramoyl-L-alanine amidase
HZZ03_RS14445	COG1172	Belongs to the binding-protein-dependent transport system permease family
HZZ03_RS14450	COG1129	ABC transporter
HZZ03_RS14455	COG0371	Dehydrogenase
HZZ03_RS14475	COG2879	small protein
HZZ03_RS14480	COG1966	Carbon starvation protein
HZZ03_RS14490	COG1028	Short-chain dehydrogenase reductase Sdr
HZZ03_RS14495	COG1535	isochorismatase
HZZ03_RS14495	COG3433	isochorismatase activity
HZZ03_RS14500	COG1021	2,3-dihydroxybenzoate-AMP ligase
HZZ03_RS14505	COG1169	isochorismate synthase
HZZ03_RS14510	COG4592	Periplasmic binding protein
HZZ03_RS14520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HZZ03_RS14525	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HZZ03_RS14530	COG1120	ATPase activity
HZZ03_RS14545	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HZZ03_RS14565	COG5342	invasion associated locus B
HZZ03_RS14575	COG2197	response regulator
HZZ03_RS14580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HZZ03_RS14595	COG1393	Belongs to the ArsC family
HZZ03_RS14610	COG0400	carboxylic ester hydrolase activity
HZZ03_RS14620	COG2321	neutral zinc metallopeptidase
HZZ03_RS14630	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HZZ03_RS14640	COG2716	regulation of RNA biosynthetic process
HZZ03_RS14645	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HZZ03_RS14650	COG0628	permease
HZZ03_RS14655	COG4783	chaperone-mediated protein folding
HZZ03_RS14660	COG1393	Belongs to the ArsC family
HZZ03_RS14670	COG2233	PERMEase
HZZ03_RS14685	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HZZ03_RS14700	COG2200	EAL domain
HZZ03_RS14715	COG0516	GMP reductase activity
HZZ03_RS14715	COG0517	IMP dehydrogenase activity
HZZ03_RS14735	COG1645	bacterial-type flagellum-dependent swarming motility
HZZ03_RS14750	COG2976	Protein conserved in bacteria
HZZ03_RS14780	COG4953	penicillin-binding protein 1C
HZZ03_RS14785	COG2373	Large extracellular alpha-helical protein
HZZ03_RS14800	COG2897	thiosulfate sulfurtransferase activity
HZZ03_RS14830	COG2975	iron-sulfur cluster assembly
HZZ03_RS14835	COG0633	Ferredoxin
HZZ03_RS14855	COG0822	iron-sulfur transferase activity
HZZ03_RS14880	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HZZ03_RS14885	COG3683	transport system, periplasmic component
HZZ03_RS14890	COG3711	transcriptional antiterminator
HZZ03_RS14895	COG2814	Major facilitator Superfamily
HZZ03_RS14905	COG0789	Transcriptional regulator
HZZ03_RS14920	COG0347	Belongs to the P(II) protein family
HZZ03_RS14925	COG2204	response regulator
HZZ03_RS14930	COG3170	Tfp pilus assembly protein FimV
HZZ03_RS14935	COG2205	protein histidine kinase activity
HZZ03_RS14940	COG0047	phosphoribosylformylglycinamidine synthase activity
HZZ03_RS14940	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HZZ03_RS14955	COG0560	Phosphoserine phosphatase
HZZ03_RS14960	COG1263	PTS System
HZZ03_RS14960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZZ03_RS14970	COG1737	Transcriptional regulator
HZZ03_RS14975	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HZZ03_RS15005	COG0681	Belongs to the peptidase S26 family
HZZ03_RS15015	COG3086	response to oxidative stress
HZZ03_RS15035	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HZZ03_RS15045	COG0513	Belongs to the DEAD box helicase family
HZZ03_RS15060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HZZ03_RS15065	COG3118	belongs to the thioredoxin family
HZZ03_RS15080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HZZ03_RS15085	COG5544	Lipoprotein
HZZ03_RS15090	COG0477	Major facilitator Superfamily
HZZ03_RS15100	COG0028	Belongs to the TPP enzyme family
HZZ03_RS15110	COG1763	Mo-molybdopterin cofactor biosynthetic process
HZZ03_RS15140	COG0542	response to heat
HZZ03_RS15155	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HZZ03_RS15165	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HZZ03_RS15170	COG1605	Chorismate mutase
HZZ03_RS15170	COG0077	Prephenate dehydratase
HZZ03_RS15180	COG0287	Prephenate dehydrogenase
HZZ03_RS15180	COG1605	Chorismate mutase
HZZ03_RS15185	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HZZ03_RS15220	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HZZ03_RS15225	COG4137	Cytochrome C assembly protein
HZZ03_RS15230	COG4536	flavin adenine dinucleotide binding
HZZ03_RS15245	COG0497	DNA recombination
HZZ03_RS15260	COG2867	negative regulation of translational initiation
HZZ03_RS15270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HZZ03_RS15275	COG1132	(ABC) transporter
HZZ03_RS15295	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HZZ03_RS15305	COG0732	type I restriction modification DNA specificity domain
HZZ03_RS15310	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HZZ03_RS15330	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HZZ03_RS15355	COG0840	transmembrane signaling receptor activity
HZZ03_RS15360	COG0401	homolog of Blt101
HZZ03_RS15385	COG4575	ribosome binding
HZZ03_RS15400	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HZZ03_RS15410	COG4175	Glycine betaine
HZZ03_RS15425	COG2814	Major facilitator Superfamily
HZZ03_RS15430	COG1846	Transcriptional regulator
HZZ03_RS15435	COG1566	PFAM secretion protein HlyD family protein
HZZ03_RS15440	COG2814	Major facilitator Superfamily
HZZ03_RS15460	COG1238	metal cluster binding
HZZ03_RS15465	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HZZ03_RS15495	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HZZ03_RS15515	COG1546	Belongs to the CinA family
HZZ03_RS15520	COG2951	lytic endotransglycosylase activity
HZZ03_RS15525	COG1126	abc transporter atp-binding protein
HZZ03_RS15530	COG0765	amino acid transport
HZZ03_RS15565	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HZZ03_RS15570	COG0163	prenyltransferase activity
HZZ03_RS15660	COG2234	aminopeptidase activity
HZZ03_RS15680	COG0720	synthase
HZZ03_RS15685	COG0602	queuosine metabolic process
HZZ03_RS15690	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HZZ03_RS15695	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HZZ03_RS15700	COG2190	(PTS) system
HZZ03_RS15700	COG1263	PTS System
HZZ03_RS15700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZZ03_RS15725	COG3956	TIGRFAM MazG family protein
HZZ03_RS15730	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HZZ03_RS15740	COG4999	Histidine kinase
HZZ03_RS15740	COG3850	Histidine kinase
HZZ03_RS15740	COG3437	response regulator, receiver
HZZ03_RS15740	COG2205	protein histidine kinase activity
HZZ03_RS15745	COG0716	FMN binding
HZZ03_RS15750	COG0564	pseudouridine synthase activity
HZZ03_RS15755	COG3098	single-species biofilm formation
HZZ03_RS15770	COG1611	Belongs to the LOG family
HZZ03_RS15775	COG0814	amino acid
HZZ03_RS15780	COG1760	l-serine dehydratase
HZZ03_RS15795	COG2363	Small membrane protein
HZZ03_RS15800	COG0583	DNA-binding transcription factor activity
HZZ03_RS15810	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HZZ03_RS15815	COG2166	iron-sulfur cluster assembly
HZZ03_RS15820	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HZZ03_RS15825	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HZZ03_RS15840	COG0860	N-Acetylmuramoyl-L-alanine amidase
HZZ03_RS15845	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HZZ03_RS15845	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HZZ03_RS15850	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HZZ03_RS15855	COG1074	ATP-dependent DNA helicase activity
HZZ03_RS15860	COG1025	Belongs to the peptidase M16 family
HZZ03_RS15865	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HZZ03_RS15870	COG4967	type IV pilus modification protein PilV
HZZ03_RS15880	COG4795	General secretion pathway protein
HZZ03_RS15885	COG2165	general secretion pathway protein
HZZ03_RS15915	COG0861	Integral membrane protein TerC family
HZZ03_RS15925	COG0667	Aldo Keto reductase
HZZ03_RS15940	COG1609	Transcriptional regulator
HZZ03_RS15950	COG2186	Transcriptional regulator
HZZ03_RS15960	COG2723	6-phospho-beta-galactosidase activity
HZZ03_RS15965	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HZZ03_RS15970	COG1609	Transcriptional regulator
HZZ03_RS15980	COG0583	DNA-binding transcription factor activity
HZZ03_RS15985	COG1794	racemase activity, acting on amino acids and derivatives
HZZ03_RS15995	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HZZ03_RS16000	COG1175	transmembrane transport
HZZ03_RS16005	COG0395	ABC-type sugar transport system, permease component
HZZ03_RS16010	COG3842	ATPase activity
HZZ03_RS16020	COG1028	Short-chain dehydrogenase reductase Sdr
HZZ03_RS16025	COG0823	Involved in the tonB-independent uptake of proteins
HZZ03_RS16035	COG0183	Belongs to the thiolase family
HZZ03_RS16055	COG4942	peptidase
HZZ03_RS16070	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HZZ03_RS16085	COG0716	FMN binding
HZZ03_RS16095	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HZZ03_RS16105	COG1272	protein, Hemolysin III
HZZ03_RS16115	COG1737	Transcriptional regulator
HZZ03_RS16120	COG2723	6-phospho-beta-galactosidase activity
HZZ03_RS16125	COG1028	Short-chain dehydrogenase reductase Sdr
HZZ03_RS16145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HZZ03_RS16150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HZZ03_RS16155	COG0006	proline dipeptidase activity
HZZ03_RS16160	COG3079	Belongs to the UPF0149 family
HZZ03_RS16175	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HZZ03_RS16180	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HZZ03_RS16195	COG2968	Membrane
HZZ03_RS16205	COG0668	transmembrane transport
HZZ03_RS16210	COG0191	fructose-bisphosphate aldolase activity
HZZ03_RS16230	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HZZ03_RS16235	COG0501	Belongs to the peptidase M48B family
HZZ03_RS16245	COG1166	arginine decarboxylase activity
HZZ03_RS16265	COG2814	Major facilitator Superfamily
HZZ03_RS16275	COG2356	endonuclease I
HZZ03_RS16280	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HZZ03_RS16315	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HZZ03_RS16320	COG0762	integral membrane protein
HZZ03_RS16335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HZZ03_RS16345	COG0204	Acyl-transferase
HZZ03_RS16355	COG2249	NAD(P)H dehydrogenase (quinone) activity
HZZ03_RS16360	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HZZ03_RS16375	COG3150	esterase
HZZ03_RS16380	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HZZ03_RS16385	COG3151	Protein conserved in bacteria
HZZ03_RS16390	COG0494	nUDIX hydrolase
HZZ03_RS16395	COG1538	Outer membrane efflux protein
HZZ03_RS16405	COG0754	glutathionylspermidine amidase activity
HZZ03_RS16410	COG3384	dioxygenase
HZZ03_RS16425	COG2960	long-chain fatty acid transporting porin activity
HZZ03_RS16440	COG3025	triphosphatase activity
HZZ03_RS16445	COG4991	sh3 domain protein
HZZ03_RS16460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HZZ03_RS16475	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HZZ03_RS16480	COG0358	DNA primase activity
HZZ03_RS16515	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HZZ03_RS16560	COG1966	Carbon starvation protein
HZZ03_RS16565	COG2879	small protein
HZZ03_RS16570	COG0523	cobalamin synthesis protein
HZZ03_RS16595	COG3171	Protein conserved in bacteria
HZZ03_RS16605	COG1194	a g-specific adenine glycosylase
HZZ03_RS16620	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
HZZ03_RS16650	COG0179	Fumarylacetoacetate (FAA) hydrolase
HZZ03_RS16655	COG3493	citrate carrier protein
HZZ03_RS16670	COG1982	Orn Lys Arg decarboxylase major
HZZ03_RS16675	COG1811	Na channel or pump
HZZ03_RS16700	COG2003	Belongs to the UPF0758 family
HZZ03_RS16710	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HZZ03_RS16725	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HZZ03_RS16730	COG4676	Protein conserved in bacteria
HZZ03_RS16735	COG5445	Predicted secreted protein (DUF2300)
HZZ03_RS16750	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
HZZ03_RS16765	COG1696	Membrane protein involved in D-alanine export
HZZ03_RS16805	COG3647	Membrane
HZZ03_RS16810	COG1609	Transcriptional regulator
HZZ03_RS16820	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HZZ03_RS16825	COG1447	Phosphotransferase system cellobiose-specific component IIA
HZZ03_RS16830	COG4580	involved in the transport of maltose and maltodextrins
HZZ03_RS16835	COG0668	transmembrane transport
HZZ03_RS16860	COG1349	DNA-binding transcription factor activity
HZZ03_RS16865	COG1028	Short-chain dehydrogenase reductase Sdr
HZZ03_RS16870	COG0848	biopolymer transport protein
HZZ03_RS16880	COG0626	cystathionine gamma-synthase activity
HZZ03_RS16885	COG0586	Pfam SNARE associated Golgi protein
HZZ03_RS16890	COG2207	Transcriptional regulator
HZZ03_RS16895	COG1979	alcohol dehydrogenase
HZZ03_RS16900	COG0656	L-ascorbic acid biosynthetic process
HZZ03_RS16920	COG1309	transcriptional regulator
HZZ03_RS16930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZZ03_RS16930	COG1263	PTS System
HZZ03_RS16935	COG0366	Alpha amylase catalytic
HZZ03_RS16940	COG2249	NAD(P)H dehydrogenase (quinone) activity
HZZ03_RS16945	COG0583	DNA-binding transcription factor activity
HZZ03_RS16955	COG0602	queuosine metabolic process
HZZ03_RS16960	COG2026	Addiction module toxin, RelE StbE family
HZZ03_RS16965	COG3077	Addiction module antitoxin, RelB DinJ family
HZZ03_RS16970	COG3711	transcriptional antiterminator
HZZ03_RS16970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HZZ03_RS16985	COG3964	amidohydrolase
HZZ03_RS17015	COG3783	Cytochrome b(562)
HZZ03_RS17020	COG0312	modulator of DNA gyrase
HZZ03_RS17035	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HZZ03_RS17050	COG1172	Belongs to the binding-protein-dependent transport system permease family
HZZ03_RS17055	COG1172	Belongs to the binding-protein-dependent transport system permease family
HZZ03_RS17060	COG1129	ABC transporter
HZZ03_RS17065	COG1879	ABC-type sugar transport system periplasmic component
HZZ03_RS17075	COG0840	transmembrane signaling receptor activity
HZZ03_RS17080	COG2105	PFAM AIG2 family protein
HZZ03_RS17085	COG2911	Protein conserved in bacteria
HZZ03_RS17105	COG1253	flavin adenine dinucleotide binding
HZZ03_RS17115	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HZZ03_RS17120	COG1218	3'(2'),5'-bisphosphate nucleotidase
HZZ03_RS17130	COG1733	regulation of RNA biosynthetic process
HZZ03_RS17135	COG0702	epimerase
HZZ03_RS17145	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HZZ03_RS17145	COG2169	Transcriptional regulator
HZZ03_RS17155	COG0697	spore germination
HZZ03_RS17160	COG0840	transmembrane signaling receptor activity
HZZ03_RS17170	COG1113	amino acid transport
HZZ03_RS17175	COG0545	Peptidyl-prolyl cis-trans isomerase
HZZ03_RS17180	COG3061	Opacity-associated protein A
HZZ03_RS17190	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HZZ03_RS17205	COG1073	alpha beta
HZZ03_RS17210	COG3650	response to hydrogen peroxide
HZZ03_RS17225	COG1960	acyl-CoA dehydrogenase activity
HZZ03_RS17230	COG0754	glutathionylspermidine amidase activity
HZZ03_RS17235	COG5463	Belongs to the UPF0441 family
HZZ03_RS17240	COG3766	membrane
HZZ03_RS17245	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HZZ03_RS17250	COG0557	exoribonuclease II activity
HZZ03_RS17265	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HZZ03_RS17270	COG0330	HflC and HflK could
HZZ03_RS17275	COG0330	HflC and HflK could
HZZ03_RS17280	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HZZ03_RS17300	COG0860	N-Acetylmuramoyl-L-alanine amidase
HZZ03_RS17305	COG0802	atpase or kinase
HZZ03_RS17310	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HZZ03_RS17310	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HZZ03_RS17315	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HZZ03_RS17350	COG3264	Mechanosensitive ion channel
HZZ03_RS17350	COG1511	domain protein
HZZ03_RS17360	COG1053	succinate dehydrogenase
HZZ03_RS17365	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HZZ03_RS17380	COG3040	lipid binding
HZZ03_RS17395	COG5510	response to toxic substance
HZZ03_RS17410	COG1509	lysine 2,3-aminomutase activity
HZZ03_RS17430	COG3030	protein affecting phage T7 exclusion by the F plasmid
HZZ03_RS17435	COG1027	Aspartate ammonia-lyase
HZZ03_RS17440	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HZZ03_RS17455	COG1309	transcriptional regulator
HZZ03_RS17480	COG2003	Belongs to the UPF0758 family
HZZ03_RS17490	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HZZ03_RS17505	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HZZ03_RS17555	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HZZ03_RS17560	COG0625	glutathione transferase activity
HZZ03_RS17580	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HZZ03_RS17585	COG2824	Alkylphosphonate utilization operon protein PhnA
HZZ03_RS17590	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
HZZ03_RS17605	COG0326	Molecular chaperone. Has ATPase activity
HZZ03_RS17620	COG1301	dicarboxylic acid transport
HZZ03_RS17630	COG3162	membrane
HZZ03_RS17635	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HZZ03_RS17640	COG0673	inositol 2-dehydrogenase activity
HZZ03_RS17645	COG0025	NhaP-type Na H and K H
HZZ03_RS17650	COG2252	PERMEase
HZZ03_RS17660	COG0789	Transcriptional regulator
HZZ03_RS17670	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HZZ03_RS17720	COG0629	single-stranded DNA binding
HZZ03_RS17725	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HZZ03_RS17740	COG2315	Protein conserved in bacteria
HZZ03_RS17745	COG0432	Pfam Uncharacterised protein family UPF0047
HZZ03_RS17750	COG2831	hemolysin activation secretion protein
HZZ03_RS17755	COG1448	Aminotransferase
HZZ03_RS17780	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HZZ03_RS17795	COG0735	belongs to the Fur family
HZZ03_RS17800	COG3237	CsbD-like
HZZ03_RS17805	COG0534	Mate efflux family protein
HZZ03_RS17815	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HZZ03_RS17875	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HZZ03_RS17900	COG0527	aspartate kinase activity
HZZ03_RS17905	COG3541	Predicted nucleotidyltransferase
HZZ03_RS17910	COG1690	Belongs to the RtcB family
HZZ03_RS17925	COG4650	regulator
HZZ03_RS17940	COG1283	sodium-dependent phosphate transmembrane transporter activity
HZZ03_RS17945	COG1410	methionine synthase
HZZ03_RS17945	COG0646	methionine synthase
HZZ03_RS17960	COG2224	Isocitrate lyase
HZZ03_RS17965	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HZZ03_RS18000	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HZZ03_RS18020	COG0551	DNA topoisomerase type I activity
HZZ03_RS18030	COG0758	DNA mediated transformation
HZZ03_RS18060	COG3036	rescue of stalled ribosome
HZZ03_RS18065	COG0789	Transcriptional regulator
HZZ03_RS18090	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HZZ03_RS18105	COG0201	protein transport
HZZ03_RS18170	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HZZ03_RS18185	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HZZ03_RS18210	COG0051	transcription antitermination factor activity, RNA binding
HZZ03_RS18265	COG2964	Protein conserved in bacteria
HZZ03_RS18270	COG0545	Peptidyl-prolyl cis-trans isomerase
HZZ03_RS18280	COG1047	Peptidyl-prolyl cis-trans
HZZ03_RS18285	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HZZ03_RS18300	COG0488	(ABC) transporter
HZZ03_RS18305	COG3853	Toxic anion resistance protein (TelA)
HZZ03_RS18320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HZZ03_RS18330	COG0429	hydrolase of the alpha beta-hydrolase fold
HZZ03_RS18340	COG3954	Phosphoribulokinase
HZZ03_RS18345	COG1765	OsmC-like protein
HZZ03_RS18355	COG1289	transmembrane transporter activity
HZZ03_RS18390	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HZZ03_RS18395	COG2146	nitrite reductase [NAD(P)H] activity
HZZ03_RS18405	COG0531	amino acid
HZZ03_RS18410	COG2222	sugar isomerase
HZZ03_RS18415	COG1082	Xylose isomerase domain protein TIM barrel
HZZ03_RS18425	COG2188	Transcriptional regulator
HZZ03_RS18435	COG0180	Tryptophanyl-tRNA synthetase
HZZ03_RS18445	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HZZ03_RS18450	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HZZ03_RS18455	COG3266	domain, Protein
HZZ03_RS18470	COG4796	Type ii and iii secretion system protein
HZZ03_RS18490	COG4972	Pilus assembly protein
HZZ03_RS18495	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HZZ03_RS18500	COG0494	nUDIX hydrolase
HZZ03_RS18510	COG1011	Hydrolase
HZZ03_RS18515	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HZZ03_RS18525	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HZZ03_RS18535	COG2205	protein histidine kinase activity
HZZ03_RS18540	COG0745	RESPONSE REGULATOR receiver
HZZ03_RS18545	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HZZ03_RS18550	COG2183	response to ionizing radiation
HZZ03_RS18555	COG1918	ferrous iron import across plasma membrane
HZZ03_RS18580	COG1040	competence protein
HZZ03_RS18590	COG1278	Cold shock
HZZ03_RS18595	COG1640	4-alpha-glucanotransferase
HZZ03_RS18600	COG0058	SHG alpha-glucan phosphorylase activity
HZZ03_RS18610	COG1349	DNA-binding transcription factor activity
HZZ03_RS18620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HZZ03_RS18625	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HZZ03_RS18630	COG4251	negative regulation of phosphorylation
HZZ03_RS18630	COG2203	Gaf domain
HZZ03_RS18630	COG5001	Diguanylate cyclase
HZZ03_RS18630	COG3706	GGDEF domain
HZZ03_RS18640	COG0058	SHG alpha-glucan phosphorylase activity
HZZ03_RS18670	COG2095	MarC family integral membrane protein
HZZ03_RS18685	COG2610	gluconate transmembrane transporter activity
HZZ03_RS18690	COG3265	gluconokinase activity
HZZ03_RS18695	COG1609	Transcriptional regulator
HZZ03_RS18700	COG1741	Belongs to the pirin family
HZZ03_RS18705	COG0673	inositol 2-dehydrogenase activity
HZZ03_RS18710	COG1247	-acetyltransferase
HZZ03_RS18715	COG0405	Gamma-glutamyltransferase
HZZ03_RS18725	COG0584	glycerophosphoryl diester phosphodiesterase
HZZ03_RS18760	COG0410	ABC transporter
HZZ03_RS18770	COG4177	L-phenylalanine transmembrane transporter activity
HZZ03_RS18780	COG0683	leucine binding
HZZ03_RS18790	COG0683	leucine binding
HZZ03_RS18800	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HZZ03_RS18810	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HZZ03_RS18815	COG2177	Part of the ABC transporter FtsEX involved in
HZZ03_RS18820	COG2884	Cell division ATP-binding protein ftsE
HZZ03_RS18825	COG0552	protein localization to endoplasmic reticulum
HZZ03_RS18830	COG0742	ribosomal rna small subunit methyltransferase
HZZ03_RS18835	COG3776	membrane
HZZ03_RS18845	COG3714	YhhN family
HZZ03_RS18865	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HZZ03_RS18875	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HZZ03_RS18890	COG0628	permease
HZZ03_RS18895	COG0791	NLP P60 protein
HZZ03_RS18900	COG0174	glutamine synthetase
HZZ03_RS18905	COG2081	HI0933 family
HZZ03_RS18910	COG0306	phosphate transporter
HZZ03_RS18935	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HZZ03_RS18940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HZZ03_RS18960	COG3111	PFAM Bacterial OB fold (BOF) protein
HZZ03_RS18965	COG1028	Short-chain dehydrogenase reductase Sdr
HZZ03_RS18970	COG0583	DNA-binding transcription factor activity
HZZ03_RS18975	COG1295	ribonuclease BN
HZZ03_RS18980	COG0477	Major facilitator Superfamily
HZZ03_RS18985	COG2982	Protein involved in outer membrane biogenesis
HZZ03_RS18990	COG2200	EAL domain
HZZ03_RS19000	COG0612	Peptidase, M16
HZZ03_RS19010	COG2200	EAL domain
HZZ03_RS19010	COG2199	diguanylate cyclase activity
HZZ03_RS19015	COG0457	Tetratricopeptide repeat
HZZ03_RS19015	COG3118	belongs to the thioredoxin family
HZZ03_RS19030	COG1215	transferase activity, transferring glycosyl groups
HZZ03_RS19055	COG2194	sulfuric ester hydrolase activity
HZZ03_RS19060	COG4608	Belongs to the ABC transporter superfamily
HZZ03_RS19065	COG0444	Belongs to the ABC transporter superfamily
HZZ03_RS19070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HZZ03_RS19075	COG0601	transmembrane transport
HZZ03_RS19080	COG0747	negative chemotaxis
HZZ03_RS19105	COG1764	response to oxidative stress
HZZ03_RS19110	COG2223	nitrite transmembrane transporter activity
HZZ03_RS19115	COG5571	outer membrane autotransporter
HZZ03_RS19120	COG2818	Glycosylase
HZZ03_RS19130	COG0243	molybdopterin cofactor binding
HZZ03_RS19135	COG2885	chlorophyll binding
HZZ03_RS19140	COG3443	Belongs to the bacterial solute-binding protein 9 family
HZZ03_RS19145	COG1609	Transcriptional regulator
HZZ03_RS19155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HZZ03_RS19180	COG2944	sequence-specific DNA binding
HZZ03_RS19205	COG3274	enterobacterial common antigen metabolic process
HZZ03_RS19215	COG1335	isochorismatase
HZZ03_RS19220	COG1070	Carbohydrate kinase
HZZ03_RS19230	COG4213	ABC transporter substrate-binding protein
HZZ03_RS19240	COG4214	carbohydrate transport
HZZ03_RS19245	COG2207	Transcriptional regulator
HZZ03_RS19245	COG1609	Transcriptional regulator
HZZ03_RS19250	COG2992	FlgJ-related protein
HZZ03_RS19255	COG0366	Alpha amylase catalytic
HZZ03_RS19260	COG3977	Valine--pyruvate aminotransferase
HZZ03_RS19265	COG1501	Belongs to the glycosyl hydrolase 31 family
HZZ03_RS19270	COG2211	Major facilitator Superfamily
HZZ03_RS19300	COG0667	Aldo Keto reductase
HZZ03_RS19305	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HZZ03_RS19310	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HZZ03_RS19315	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HZZ03_RS19320	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HZZ03_RS19325	COG2080	2 iron, 2 sulfur cluster binding
HZZ03_RS19345	COG1064	alcohol dehydrogenase
HZZ03_RS19365	COG2205	protein histidine kinase activity
HZZ03_RS19370	COG0745	RESPONSE REGULATOR receiver
HZZ03_RS19375	COG2351	hydroxyisourate hydrolase activity
HZZ03_RS19410	COG3678	ATP-independent chaperone mediated protein folding
HZZ03_RS19415	COG0745	RESPONSE REGULATOR receiver
HZZ03_RS19420	COG2205	protein histidine kinase activity
HZZ03_RS19425	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HZZ03_RS19445	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HZZ03_RS19450	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HZZ03_RS19460	COG4942	peptidase
HZZ03_RS19465	COG2861	carbohydrate metabolic process
HZZ03_RS19470	COG0463	Glycosyl transferase, family 2
HZZ03_RS19480	COG0156	8-amino-7-oxononanoate synthase activity
HZZ03_RS19490	COG0859	PFAM glycosyl transferase family 9
HZZ03_RS19495	COG0859	PFAM glycosyl transferase family 9
HZZ03_RS19500	COG0859	PFAM glycosyl transferase family 9
HZZ03_RS19505	COG0438	transferase activity, transferring glycosyl groups
HZZ03_RS19510	COG0438	transferase activity, transferring glycosyl groups
HZZ03_RS19520	COG1216	Glycosyl transferase, family 2
HZZ03_RS19535	COG1519	Transferase
HZZ03_RS19555	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HZZ03_RS19560	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HZZ03_RS19570	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HZZ03_RS19595	COG1561	YicC-like family, N-terminal region
HZZ03_RS19600	COG2860	membrane
HZZ03_RS19610	COG0194	GDP metabolic process
HZZ03_RS19620	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HZZ03_RS19625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HZZ03_RS19630	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HZZ03_RS19640	COG3121	Chaperone
HZZ03_RS19645	COG3188	usher protein
HZZ03_RS19670	COG2233	PERMEase
HZZ03_RS19675	COG2982	Protein involved in outer membrane biogenesis
HZZ03_RS19680	COG0456	acetyltransferase
HZZ03_RS19695	COG1011	Hydrolase
HZZ03_RS19700	COG1349	DNA-binding transcription factor activity
HZZ03_RS19705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HZZ03_RS19710	COG2084	Dehydrogenase
HZZ03_RS19725	COG2017	converts alpha-aldose to the beta-anomer
HZZ03_RS19730	COG1501	Belongs to the glycosyl hydrolase 31 family
HZZ03_RS19750	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HZZ03_RS19765	COG3852	Histidine kinase
HZZ03_RS19780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HZZ03_RS19800	COG0204	Acyl-transferase
HZZ03_RS19810	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HZZ03_RS19815	COG3084	Protein conserved in bacteria
HZZ03_RS19820	COG0746	molybdenum cofactor guanylyltransferase activity
HZZ03_RS19825	COG1763	Mo-molybdopterin cofactor biosynthetic process
HZZ03_RS19850	COG2186	Transcriptional regulator
HZZ03_RS19855	COG0477	Major facilitator Superfamily
HZZ03_RS19860	COG1609	Transcriptional regulator
HZZ03_RS19865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HZZ03_RS19875	COG1172	Belongs to the binding-protein-dependent transport system permease family
HZZ03_RS19880	COG1129	ABC transporter
HZZ03_RS19910	COG1522	sequence-specific DNA binding
HZZ03_RS19915	COG0716	FMN binding
HZZ03_RS19930	COG3312	ion transport
HZZ03_RS19995	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HZZ03_RS20000	COG0573	inorganic phosphate transmembrane transporter activity
HZZ03_RS20005	COG0581	inorganic phosphate transmembrane transporter activity
HZZ03_RS20010	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HZZ03_RS20015	COG0704	Plays a role in the regulation of phosphate uptake
HZZ03_RS20020	COG2382	esterase
HZZ03_RS20025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HZZ03_RS20030	COG2252	PERMEase
HZZ03_RS20035	COG0431	NADPH-dependent FMN reductase
HZZ03_RS20040	COG2091	lysine biosynthetic process via aminoadipic acid
HZZ03_RS20060	COG1296	Branched-chain amino acid permease (Azaleucine resistance)