locus-tag	class	description
BKK81_RS00005	COG0154	amidase activity
BKK81_RS00030	COG0625	glutathione transferase activity
BKK81_RS00035	COG2857	Cytochrome c1
BKK81_RS00040	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BKK81_RS00045	COG0723	plastoquinol--plastocyanin reductase activity
BKK81_RS00050	COG1970	mechanosensitive ion channel activity
BKK81_RS00055	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BKK81_RS00060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKK81_RS00065	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BKK81_RS00070	COG0805	protein transport
BKK81_RS00075	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BKK81_RS00080	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BKK81_RS00090	COG0140	phosphoribosyl-ATP diphosphatase activity
BKK81_RS00095	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BKK81_RS00100	COG0107	imidazoleglycerol-phosphate synthase activity
BKK81_RS00105	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BKK81_RS00110	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BKK81_RS00115	COG2095	MarC family integral membrane protein
BKK81_RS00120	COG0131	Imidazoleglycerol-phosphate dehydratase
BKK81_RS00125	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BKK81_RS00130	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BKK81_RS00135	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BKK81_RS00140	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BKK81_RS00150	COG0842	Transport permease protein
BKK81_RS00155	COG1131	(ABC) transporter
BKK81_RS00170	COG2853	Lipoprotein
BKK81_RS00175	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BKK81_RS00180	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BKK81_RS00185	COG1127	ABC transporter
BKK81_RS00205	COG0070	glutamate synthase
BKK81_RS00205	COG0069	glutamate synthase activity
BKK81_RS00205	COG0067	glutamate synthase
BKK81_RS00215	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BKK81_RS00220	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BKK81_RS00225	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BKK81_RS00260	COG1965	Belongs to the frataxin family
BKK81_RS00275	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BKK81_RS00280	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BKK81_RS00290	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BKK81_RS00295	COG1333	cytochrome c biogenesis protein
BKK81_RS00305	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BKK81_RS00315	COG0598	Magnesium transport protein CorA
BKK81_RS00320	COG4232	protein-disulfide reductase activity
BKK81_RS00330	COG0203	ribosomal protein L17
BKK81_RS00335	COG0202	RNA polymerase activity
BKK81_RS00340	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BKK81_RS00345	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BKK81_RS00350	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BKK81_RS00355	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BKK81_RS00360	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BKK81_RS00365	COG0201	protein transport
BKK81_RS00370	COG0200	Binds to the 23S rRNA
BKK81_RS00375	COG1841	ribosomal large subunit assembly
BKK81_RS00380	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BKK81_RS00385	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BKK81_RS00390	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BKK81_RS00395	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BKK81_RS00400	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BKK81_RS00405	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BKK81_RS00410	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BKK81_RS00415	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BKK81_RS00420	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BKK81_RS00425	COG0255	Belongs to the universal ribosomal protein uL29 family
BKK81_RS00430	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BKK81_RS00435	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BKK81_RS00440	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BKK81_RS00445	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BKK81_RS00450	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BKK81_RS00455	COG0089	rRNA binding
BKK81_RS00460	COG0088	Forms part of the polypeptide exit tunnel
BKK81_RS00465	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BKK81_RS00495	COG0051	transcription antitermination factor activity, RNA binding
BKK81_RS00500	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BKK81_RS00505	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BKK81_RS00510	COG0049	tRNA binding
BKK81_RS00515	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BKK81_RS00520	COG0514	ATP-dependent DNA helicase (RecQ)
BKK81_RS00525	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BKK81_RS00530	COG0085	RNA polymerase activity
BKK81_RS00535	COG0222	ribosome binding
BKK81_RS00540	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BKK81_RS00545	COG0081	regulation of translation
BKK81_RS00550	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BKK81_RS00570	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BKK81_RS00615	COG0700	Nucleoside recognition
BKK81_RS00630	COG0589	response to stress
BKK81_RS00650	COG3396	Phenylacetate-CoA oxygenase
BKK81_RS00655	COG3460	Phenylacetate-CoA oxygenase
BKK81_RS00660	COG3396	Phenylacetate-CoA oxygenase
BKK81_RS00665	COG2151	metal-sulfur cluster biosynthetic enzyme
BKK81_RS00670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BKK81_RS00785	COG0456	acetyltransferase
BKK81_RS00805	COG3384	dioxygenase
BKK81_RS00820	COG2818	Glycosylase
BKK81_RS00845	COG0737	Belongs to the 5'-nucleotidase family
BKK81_RS00850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKK81_RS00855	COG2010	Cytochrome c
BKK81_RS00880	COG4654	Cytochrome c, class I
BKK81_RS00885	COG4654	Cytochrome c, class I
BKK81_RS00890	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BKK81_RS00895	COG0640	Transcriptional regulator
BKK81_RS00900	COG0446	pyridine nucleotide-disulphide oxidoreductase
BKK81_RS00910	COG2823	Periplasmic or secreted lipoprotein
BKK81_RS00915	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BKK81_RS00920	COG0792	nuclease activity
BKK81_RS00935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKK81_RS00950	COG1393	Belongs to the ArsC family
BKK81_RS00965	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BKK81_RS00975	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKK81_RS00980	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKK81_RS00990	COG1301	dicarboxylic acid transport
BKK81_RS01000	COG0300	oxidoreductase activity
BKK81_RS01005	COG1024	Enoyl-CoA hydratase
BKK81_RS01010	COG0318	PFAM AMP-dependent synthetase and ligase
BKK81_RS01015	COG1024	Enoyl-CoA hydratase
BKK81_RS01025	COG0583	DNA-binding transcription factor activity
BKK81_RS01040	COG1473	amidohydrolase
BKK81_RS01045	COG3960	tartronate-semialdehyde synthase activity
BKK81_RS01050	COG3622	Belongs to the hyi family
BKK81_RS01055	COG2084	Dehydrogenase
BKK81_RS01065	COG0469	pyruvate kinase activity
BKK81_RS01070	COG2321	neutral zinc metallopeptidase
BKK81_RS01075	COG1309	transcriptional regulator
BKK81_RS01080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKK81_RS01090	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BKK81_RS01100	COG0789	Transcriptional regulator
BKK81_RS01110	COG0501	Belongs to the peptidase M48B family
BKK81_RS01115	COG4977	sequence-specific DNA binding
BKK81_RS01120	COG2814	Major facilitator Superfamily
BKK81_RS01125	COG2124	cytochrome p450
BKK81_RS01125	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BKK81_RS01130	COG1309	transcriptional regulator
BKK81_RS01175	COG3245	cytochrome
BKK81_RS01180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BKK81_RS01200	COG0210	DNA helicase
BKK81_RS01210	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BKK81_RS01215	COG0509	glycine decarboxylation via glycine cleavage system
BKK81_RS01220	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BKK81_RS01220	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BKK81_RS01225	COG2323	membrane
BKK81_RS01230	COG1760	l-serine dehydratase
BKK81_RS01240	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BKK81_RS01255	COG0683	leucine binding
BKK81_RS01260	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BKK81_RS01260	COG0506	proline dehydrogenase activity
BKK81_RS01260	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BKK81_RS01265	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BKK81_RS01270	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BKK81_RS01280	COG1832	CoA-binding protein
BKK81_RS01285	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BKK81_RS01290	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BKK81_RS01295	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BKK81_RS01300	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BKK81_RS01305	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BKK81_RS01310	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BKK81_RS01320	COG0356	it plays a direct role in the translocation of protons across the membrane
BKK81_RS01335	COG1192	Involved in chromosome partitioning
BKK81_RS01340	COG0357	Ribosomal RNA small subunit methyltransferase G
BKK81_RS01345	COG0445	tRNA wobble uridine modification
BKK81_RS01355	COG3181	Tripartite tricarboxylate transporter family receptor
BKK81_RS01360	COG0583	DNA-binding transcription factor activity
BKK81_RS01395	COG0559	Belongs to the binding-protein-dependent transport system permease family
BKK81_RS01420	COG0583	DNA-binding transcription factor activity
BKK81_RS01425	COG2267	carboxylic ester hydrolase activity
BKK81_RS01430	COG0789	Transcriptional regulator
BKK81_RS01435	COG2217	Heavy metal translocating P-type atpase
BKK81_RS01445	COG3047	cAMP biosynthetic process
BKK81_RS01450	COG2423	ornithine cyclodeaminase activity
BKK81_RS01470	COG1522	sequence-specific DNA binding
BKK81_RS01475	COG3186	Phenylalanine-4-hydroxylase
BKK81_RS01480	COG2154	pterin-4-alpha-carbinolamine dehydratase
BKK81_RS01490	COG0642	Histidine kinase
BKK81_RS01515	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BKK81_RS01525	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BKK81_RS01555	COG2204	response regulator
BKK81_RS01560	COG5000	phosphorelay sensor kinase activity
BKK81_RS01575	COG0501	Belongs to the peptidase M48B family
BKK81_RS01580	COG1280	lysine exporter protein (LysE YggA)
BKK81_RS01585	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BKK81_RS01590	COG0242	peptide deformylase activity
BKK81_RS01595	COG1652	LysM domain
BKK81_RS01600	COG0758	DNA mediated transformation
BKK81_RS01615	COG0583	DNA-binding transcription factor activity
BKK81_RS01630	COG2879	small protein
BKK81_RS01635	COG1966	Carbon starvation protein
BKK81_RS01650	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BKK81_RS01655	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKK81_RS01660	COG2814	Major facilitator Superfamily
BKK81_RS01665	COG2258	MOSC domain
BKK81_RS01685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKK81_RS01735	COG1309	transcriptional regulator
BKK81_RS01740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKK81_RS01745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKK81_RS01755	COG4941	Belongs to the sigma-70 factor family
BKK81_RS01780	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BKK81_RS01805	COG2267	carboxylic ester hydrolase activity
BKK81_RS01825	COG0583	DNA-binding transcription factor activity
BKK81_RS01850	COG0281	malic enzyme
BKK81_RS01850	COG0280	phosphate acetyltransferase
BKK81_RS01870	COG1960	acyl-CoA dehydrogenase activity
BKK81_RS01875	COG1024	Enoyl-CoA hydratase
BKK81_RS01915	COG4968	Prepilin-type N-terminal cleavage methylation domain
BKK81_RS01945	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BKK81_RS01980	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BKK81_RS01995	COG4106	trans-aconitate 2-methyltransferase activity
BKK81_RS02000	COG0583	DNA-binding transcription factor activity
BKK81_RS02005	COG1846	Transcriptional regulator
BKK81_RS02010	COG1764	response to oxidative stress
BKK81_RS02015	COG0706	membrane insertase activity
BKK81_RS02020	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BKK81_RS02025	COG0594	ribonuclease P activity
BKK81_RS02030	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BKK81_RS02035	COG0592	DNA-directed DNA polymerase activity
BKK81_RS02045	COG4566	intracellular signal transduction
BKK81_RS02060	COG1028	Short-chain dehydrogenase reductase Sdr
BKK81_RS02075	COG4095	Psort location CytoplasmicMembrane, score
BKK81_RS02100	COG4191	Histidine kinase
BKK81_RS02120	COG2366	antibiotic biosynthetic process
BKK81_RS02130	COG0145	ligase activity
BKK81_RS02135	COG4647	ligase activity
BKK81_RS02140	COG0145	ligase activity
BKK81_RS02145	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
BKK81_RS02155	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKK81_RS02205	COG0583	DNA-binding transcription factor activity
BKK81_RS02215	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BKK81_RS02220	COG2814	Major facilitator Superfamily
BKK81_RS02240	COG3550	peptidyl-serine autophosphorylation
BKK81_RS02255	COG1595	DNA-templated transcription, initiation
BKK81_RS02295	COG1074	ATP-dependent DNA helicase activity
BKK81_RS02310	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BKK81_RS02320	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BKK81_RS02325	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BKK81_RS02330	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKK81_RS02340	COG1401	restriction endodeoxyribonuclease activity
BKK81_RS02365	COG5001	Diguanylate cyclase
BKK81_RS02365	COG2203	Gaf domain
BKK81_RS02365	COG3706	GGDEF domain
BKK81_RS02365	COG4251	negative regulation of phosphorylation
BKK81_RS02505	COG0477	Major facilitator Superfamily
BKK81_RS02510	COG0583	DNA-binding transcription factor activity
BKK81_RS02530	COG2733	membrane
BKK81_RS02540	COG0583	DNA-binding transcription factor activity
BKK81_RS02550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKK81_RS02555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKK81_RS02580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BKK81_RS02595	COG1802	Transcriptional regulator
BKK81_RS02605	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BKK81_RS02610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKK81_RS02615	COG4172	Belongs to the ABC transporter superfamily
BKK81_RS02620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKK81_RS02625	COG0601	transmembrane transport
BKK81_RS02630	COG0747	negative chemotaxis
BKK81_RS02640	COG1126	abc transporter atp-binding protein
BKK81_RS02645	COG0765	amino acid transport
BKK81_RS02650	COG0765	amino acid transport
BKK81_RS02670	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BKK81_RS02690	COG0513	Belongs to the DEAD box helicase family
BKK81_RS02710	COG0517	IMP dehydrogenase activity
BKK81_RS02735	COG0426	domain, Protein
BKK81_RS02735	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BKK81_RS02745	COG0583	DNA-binding transcription factor activity
BKK81_RS02765	COG2271	Major facilitator Superfamily
BKK81_RS02770	COG1802	Transcriptional regulator
BKK81_RS02775	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKK81_RS02780	COG1473	amidohydrolase
BKK81_RS02785	COG2207	Transcriptional regulator
BKK81_RS02790	COG2223	nitrite transmembrane transporter activity
BKK81_RS02800	COG1846	Transcriptional regulator
BKK81_RS02805	COG0697	spore germination
BKK81_RS02825	COG0745	RESPONSE REGULATOR receiver
BKK81_RS02830	COG0745	RESPONSE REGULATOR receiver
BKK81_RS02835	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BKK81_RS02840	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BKK81_RS02845	COG2894	cell division
BKK81_RS02850	COG0850	regulation of cytokinetic process
BKK81_RS02865	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BKK81_RS02870	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BKK81_RS02875	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BKK81_RS02880	COG2205	protein histidine kinase activity
BKK81_RS02885	COG0745	RESPONSE REGULATOR receiver
BKK81_RS02910	COG0772	Belongs to the SEDS family
BKK81_RS02915	COG0768	penicillin binding
BKK81_RS02925	COG1792	Involved in formation and maintenance of cell shape
BKK81_RS02930	COG1077	Cell shape determining protein MreB Mrl
BKK81_RS02935	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BKK81_RS02940	COG0154	amidase activity
BKK81_RS02955	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BKK81_RS02965	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BKK81_RS02970	COG0583	DNA-binding transcription factor activity
BKK81_RS02980	COG0321	lipoyl(octanoyl) transferase activity
BKK81_RS02985	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BKK81_RS02990	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BKK81_RS02995	COG1984	allophanate hydrolase subunit 2
BKK81_RS03000	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BKK81_RS03015	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BKK81_RS03035	COG1127	ABC transporter
BKK81_RS03040	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BKK81_RS03050	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BKK81_RS03060	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BKK81_RS03080	COG1024	Enoyl-CoA hydratase
BKK81_RS03105	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BKK81_RS03135	COG2197	response regulator
BKK81_RS03160	COG5487	UPF0391 membrane protein
BKK81_RS03175	COG0018	arginyl-trna synthetase
BKK81_RS03185	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BKK81_RS03190	COG4221	oxidoreductase activity
BKK81_RS03195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BKK81_RS03215	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BKK81_RS03220	COG0288	reversible hydration of carbon dioxide
BKK81_RS03225	COG0183	Belongs to the thiolase family
BKK81_RS03230	COG1028	Short-chain dehydrogenase reductase Sdr
BKK81_RS03235	COG1960	acyl-CoA dehydrogenase activity
BKK81_RS03245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKK81_RS03250	COG3012	SEC-C Motif Domain Protein
BKK81_RS03265	COG0156	8-amino-7-oxononanoate synthase activity
BKK81_RS03270	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BKK81_RS03275	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BKK81_RS03285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKK81_RS03305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKK81_RS03310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKK81_RS03315	COG4771	TonB-dependent receptor
BKK81_RS03335	COG0523	cobalamin synthesis protein
BKK81_RS03345	COG0596	Alpha beta hydrolase
BKK81_RS03355	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BKK81_RS03360	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BKK81_RS03365	COG3237	CsbD-like
BKK81_RS03385	COG2847	Copper chaperone PCu(A)C
BKK81_RS03390	COG0583	DNA-binding transcription factor activity
BKK81_RS03410	COG1595	DNA-templated transcription, initiation
BKK81_RS03415	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BKK81_RS03425	COG1309	transcriptional regulator
BKK81_RS03430	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BKK81_RS03455	COG2223	nitrite transmembrane transporter activity
BKK81_RS03460	COG0501	Belongs to the peptidase M48B family
BKK81_RS03465	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BKK81_RS03470	COG0708	Exodeoxyribonuclease III
BKK81_RS03475	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BKK81_RS03485	COG2326	polyphosphate kinase activity
BKK81_RS03490	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BKK81_RS03495	COG1560	Kdo2-lipid A biosynthetic process
BKK81_RS03505	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BKK81_RS03520	COG0840	transmembrane signaling receptor activity
BKK81_RS03525	COG1960	acyl-CoA dehydrogenase activity
BKK81_RS03530	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BKK81_RS03545	COG2022	thiamine diphosphate biosynthetic process
BKK81_RS03565	COG4770	biotin carboxylase activity
BKK81_RS03580	COG0351	phosphomethylpyrimidine kinase
BKK81_RS03580	COG0352	thiamine-phosphate diphosphorylase activity
BKK81_RS03585	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BKK81_RS03590	COG1950	PFAM Membrane protein of
BKK81_RS03595	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BKK81_RS03615	COG1785	Belongs to the alkaline phosphatase family
BKK81_RS03625	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BKK81_RS03630	COG0741	lytic transglycosylase activity
BKK81_RS03645	COG0617	tRNA 3'-terminal CCA addition
BKK81_RS03670	COG0037	tRNA processing
BKK81_RS03680	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BKK81_RS03685	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BKK81_RS03690	COG1011	Hydrolase
BKK81_RS03695	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BKK81_RS03705	COG2423	ornithine cyclodeaminase activity
BKK81_RS03710	COG1301	dicarboxylic acid transport
BKK81_RS03725	COG4206	TonB-dependent receptor
BKK81_RS03735	COG3720	iron ion transport
BKK81_RS03740	COG4558	Periplasmic binding protein
BKK81_RS03745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKK81_RS03750	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BKK81_RS03755	COG0477	Major facilitator Superfamily
BKK81_RS03775	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BKK81_RS03780	COG1230	cation diffusion facilitator family transporter
BKK81_RS03785	COG0583	DNA-binding transcription factor activity
BKK81_RS03790	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BKK81_RS03795	COG0066	3-isopropylmalate dehydratase activity
BKK81_RS03810	COG3181	Tripartite tricarboxylate transporter family receptor
BKK81_RS03825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKK81_RS03830	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BKK81_RS03835	COG0531	amino acid
BKK81_RS03850	COG1703	isobutyryl-CoA mutase activity
BKK81_RS03850	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BKK81_RS03850	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BKK81_RS03855	COG0537	adenosine 5'-monophosphoramidase activity
BKK81_RS03860	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKK81_RS03865	COG4574	serine-type endopeptidase inhibitor activity
BKK81_RS03875	COG1022	Amp-dependent synthetase and ligase
BKK81_RS03910	COG2832	Protein of unknown function (DUF454)
BKK81_RS03920	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BKK81_RS03925	COG2921	Belongs to the UPF0250 family
BKK81_RS03930	COG1686	Belongs to the peptidase S11 family
BKK81_RS03935	COG2945	thiolester hydrolase activity
BKK81_RS03940	COG3411	Ferredoxin
BKK81_RS03945	COG1301	dicarboxylic acid transport
BKK81_RS03955	COG2204	response regulator
BKK81_RS03965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKK81_RS03980	COG1280	lysine exporter protein (LysE YggA)
BKK81_RS03990	COG2960	long-chain fatty acid transporting porin activity
BKK81_RS04005	COG0004	ammonium transporteR
BKK81_RS04015	COG0189	ligase activity
BKK81_RS04025	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKK81_RS04030	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BKK81_RS04045	COG0709	Synthesizes selenophosphate from selenide and ATP
BKK81_RS04050	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BKK81_RS04055	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BKK81_RS04060	COG0793	Belongs to the peptidase S41A family
BKK81_RS04065	COG0588	phosphoglycerate mutase activity
BKK81_RS04070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BKK81_RS04075	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BKK81_RS04080	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BKK81_RS04085	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BKK81_RS04100	COG1040	competence protein
BKK81_RS04105	COG2226	methyltransferase
BKK81_RS04120	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BKK81_RS04155	COG1612	heme a metabolic process
BKK81_RS04160	COG0109	protoheme IX farnesyltransferase activity
BKK81_RS04165	COG1999	signal sequence binding
BKK81_RS04170	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BKK81_RS04175	COG1741	Belongs to the pirin family
BKK81_RS04180	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BKK81_RS04190	COG0625	glutathione transferase activity
BKK81_RS04200	COG0612	Peptidase, M16
BKK81_RS04205	COG0612	Peptidase, M16
BKK81_RS04210	COG0742	ribosomal rna small subunit methyltransferase
BKK81_RS04215	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BKK81_RS04220	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BKK81_RS04225	COG0193	aminoacyl-tRNA hydrolase activity
BKK81_RS04230	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BKK81_RS04235	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BKK81_RS04250	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BKK81_RS04255	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BKK81_RS04265	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BKK81_RS04275	COG1194	a g-specific adenine glycosylase
BKK81_RS04285	COG1660	Displays ATPase and GTPase activities
BKK81_RS04295	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BKK81_RS04305	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BKK81_RS04310	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BKK81_RS04315	COG1137	ATPase activity
BKK81_RS04345	COG0693	protein deglycase activity
BKK81_RS04350	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BKK81_RS04360	COG1283	sodium-dependent phosphate transmembrane transporter activity
BKK81_RS04375	COG2814	Major facilitator Superfamily
BKK81_RS04380	COG0629	single-stranded DNA binding
BKK81_RS04400	COG2132	Multicopper oxidase
BKK81_RS04410	COG5002	protein histidine kinase activity
BKK81_RS04430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKK81_RS04440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BKK81_RS04445	COG3246	L-lysine catabolic process to acetate
BKK81_RS04455	COG0436	Aminotransferase
BKK81_RS04465	COG0842	Transport permease protein
BKK81_RS04470	COG1131	(ABC) transporter
BKK81_RS04505	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BKK81_RS04505	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BKK81_RS04510	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BKK81_RS04515	COG1877	trehalose-phosphatase activity
BKK81_RS04535	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BKK81_RS04570	COG1238	metal cluster binding
BKK81_RS04585	COG4178	(ABC) transporter
BKK81_RS04595	COG2226	methyltransferase
BKK81_RS04610	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BKK81_RS04630	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BKK81_RS04640	COG0494	nUDIX hydrolase
BKK81_RS04655	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BKK81_RS04665	COG1960	acyl-CoA dehydrogenase activity
BKK81_RS04670	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKK81_RS04670	COG1024	Enoyl-CoA hydratase
BKK81_RS04675	COG0183	Belongs to the thiolase family
BKK81_RS04680	COG1024	Enoyl-CoA hydratase
BKK81_RS04685	COG0318	PFAM AMP-dependent synthetase and ligase
BKK81_RS04690	COG1607	acyl-coa hydrolase
BKK81_RS04695	COG5265	(ABC) transporter
BKK81_RS04705	COG1116	anion transmembrane transporter activity
BKK81_RS04710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKK81_RS04715	COG1522	sequence-specific DNA binding
BKK81_RS04725	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BKK81_RS04735	COG0765	amino acid transport
BKK81_RS04740	COG0765	amino acid transport
BKK81_RS04745	COG1126	abc transporter atp-binding protein
BKK81_RS04750	COG0121	glutamine amidotransferase
BKK81_RS04755	COG0473	3-isopropylmalate dehydrogenase activity
BKK81_RS04765	COG0418	dihydroorotase activity
BKK81_RS04775	COG0612	Peptidase, M16
BKK81_RS04790	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BKK81_RS04795	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BKK81_RS04805	COG0316	Belongs to the HesB IscA family
BKK81_RS04820	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BKK81_RS04830	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BKK81_RS04835	COG1490	D-aminoacyl-tRNA deacylase activity
BKK81_RS04840	COG1881	PFAM PEBP family protein
BKK81_RS04845	COG0406	alpha-ribazole phosphatase activity
BKK81_RS04860	COG2255	four-way junction helicase activity
BKK81_RS04865	COG0632	four-way junction helicase activity
BKK81_RS04870	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BKK81_RS04875	COG0138	bifunctional purine biosynthesis protein purh
BKK81_RS04880	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BKK81_RS04890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKK81_RS04900	COG0006	proline dipeptidase activity
BKK81_RS04925	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BKK81_RS04930	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKK81_RS04935	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BKK81_RS04940	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BKK81_RS04950	COG0346	lactoylglutathione lyase activity
BKK81_RS04960	COG0204	Acyl-transferase
BKK81_RS04965	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BKK81_RS04970	COG0751	glycine-tRNA ligase activity
BKK81_RS04980	COG0752	glycyl-tRNA synthetase alpha subunit
BKK81_RS04985	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BKK81_RS04990	COG4535	Mg2 and Co2 transporter CorC
BKK81_RS04995	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BKK81_RS05000	COG1702	phosphate starvation-inducible protein PhoH
BKK81_RS05005	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BKK81_RS05015	COG0038	chloride channel
BKK81_RS05020	COG0513	Belongs to the DEAD box helicase family
BKK81_RS05035	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKK81_RS05040	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKK81_RS05055	COG2011	ABC-type metal ion transport system permease component
BKK81_RS05060	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BKK81_RS05065	COG1464	Belongs to the NlpA lipoprotein family
BKK81_RS05075	COG2814	Major facilitator Superfamily
BKK81_RS05090	COG2072	flavoprotein involved in K transport
BKK81_RS05110	COG0583	DNA-binding transcription factor activity
BKK81_RS05120	COG2807	transmembrane transport
BKK81_RS05180	COG4964	Belongs to the GSP D family
BKK81_RS05215	COG5295	Hep Hag repeat protein
BKK81_RS05220	COG2885	chlorophyll binding
BKK81_RS05220	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BKK81_RS05240	COG2274	protein secretion by the type I secretion system
BKK81_RS05300	COG0642	Histidine kinase
BKK81_RS05310	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BKK81_RS05315	COG2137	regulation of response to DNA damage stimulus
BKK81_RS05325	COG0045	succinate-CoA ligase (ADP-forming) activity
BKK81_RS05330	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BKK81_RS05335	COG0861	Integral membrane protein TerC family
BKK81_RS05345	COG3307	-O-antigen
BKK81_RS05405	COG0315	cyclic pyranopterin monophosphate synthase activity
BKK81_RS05410	COG4783	chaperone-mediated protein folding
BKK81_RS05420	COG0429	hydrolase of the alpha beta-hydrolase fold
BKK81_RS05430	COG0859	PFAM glycosyl transferase family 9
BKK81_RS05440	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BKK81_RS05470	COG0126	phosphoglycerate kinase activity
BKK81_RS05475	COG0469	pyruvate kinase activity
BKK81_RS05485	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BKK81_RS05490	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BKK81_RS05495	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BKK81_RS05500	COG0009	L-threonylcarbamoyladenylate synthase
BKK81_RS05565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKK81_RS05570	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKK81_RS05590	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BKK81_RS05595	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BKK81_RS05605	COG0154	amidase activity
BKK81_RS05610	COG1802	Transcriptional regulator
BKK81_RS05615	COG4974	Belongs to the 'phage' integrase family
BKK81_RS05640	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BKK81_RS05645	COG0802	atpase or kinase
BKK81_RS05650	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKK81_RS05660	COG0583	DNA-binding transcription factor activity
BKK81_RS05665	COG2226	methyltransferase
BKK81_RS05680	COG0563	adenylate kinase activity
BKK81_RS05685	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BKK81_RS05690	COG2835	tetraacyldisaccharide 4'-kinase activity
BKK81_RS05695	COG1663	tetraacyldisaccharide 4'-kinase activity
BKK81_RS05705	COG0811	peptide transport
BKK81_RS05710	COG1570	exodeoxyribonuclease VII activity
BKK81_RS05720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKK81_RS05725	COG1960	acyl-CoA dehydrogenase activity
BKK81_RS05730	COG0583	DNA-binding transcription factor activity
BKK81_RS05785	COG1910	domain protein
BKK81_RS05800	COG3383	formate dehydrogenase (NAD+) activity
BKK81_RS05810	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BKK81_RS05815	COG0471	metal ion transport
BKK81_RS05820	COG2365	Tyrosine phosphatase family
BKK81_RS05825	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BKK81_RS05865	COG4149	molybdate abc transporter
BKK81_RS05870	COG0725	ABC transporter, periplasmic molybdate-binding protein
BKK81_RS05875	COG0737	Belongs to the 5'-nucleotidase family
BKK81_RS05890	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKK81_RS05895	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BKK81_RS05905	COG3181	Tripartite tricarboxylate transporter family receptor
BKK81_RS05940	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BKK81_RS05940	COG3008	intermembrane lipid transfer
BKK81_RS05945	COG2995	paraquat-inducible protein a
BKK81_RS05955	COG0628	permease
BKK81_RS05960	COG4569	acetaldehyde dehydrogenase (acetylating) activity
BKK81_RS05965	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKK81_RS05970	COG1414	Transcriptional regulator
BKK81_RS05975	COG0277	FAD linked oxidase domain protein
BKK81_RS06010	COG0516	GMP reductase activity
BKK81_RS06010	COG0517	IMP dehydrogenase activity
BKK81_RS06080	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BKK81_RS06120	COG0840	transmembrane signaling receptor activity
BKK81_RS06145	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BKK81_RS06205	COG2076	Multidrug Resistance protein
BKK81_RS06225	COG5002	protein histidine kinase activity
BKK81_RS06230	COG0789	Transcriptional regulator
BKK81_RS06235	COG0702	epimerase
BKK81_RS06270	COG1522	sequence-specific DNA binding
BKK81_RS06280	COG2423	ornithine cyclodeaminase activity
BKK81_RS06285	COG1028	Short-chain dehydrogenase reductase Sdr
BKK81_RS06305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BKK81_RS06315	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BKK81_RS06320	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BKK81_RS06325	COG0673	inositol 2-dehydrogenase activity
BKK81_RS06340	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BKK81_RS06350	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BKK81_RS06375	COG0318	PFAM AMP-dependent synthetase and ligase
BKK81_RS06400	COG2197	response regulator
BKK81_RS06410	COG5001	Diguanylate cyclase
BKK81_RS06410	COG3300	MHYT domain
BKK81_RS06465	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BKK81_RS06500	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BKK81_RS06535	COG4191	Histidine kinase
BKK81_RS06540	COG1301	dicarboxylic acid transport
BKK81_RS06550	COG5002	protein histidine kinase activity
BKK81_RS06550	COG3447	MASE1 domain protein
BKK81_RS06550	COG5001	Diguanylate cyclase
BKK81_RS06560	COG2010	Cytochrome c
BKK81_RS06560	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BKK81_RS06565	COG5001	Diguanylate cyclase
BKK81_RS06565	COG2203	Gaf domain
BKK81_RS06565	COG3706	GGDEF domain
BKK81_RS06565	COG4251	negative regulation of phosphorylation
BKK81_RS06575	COG1595	DNA-templated transcription, initiation
BKK81_RS06580	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BKK81_RS06590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKK81_RS06630	COG3246	L-lysine catabolic process to acetate
BKK81_RS06635	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKK81_RS06645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKK81_RS06655	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BKK81_RS06660	COG0459	protein refolding
BKK81_RS06675	COG0297	glycogen (starch) synthase activity
BKK81_RS06685	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BKK81_RS06745	COG4964	Belongs to the GSP D family
BKK81_RS06755	COG1401	restriction endodeoxyribonuclease activity
BKK81_RS06780	COG0463	Glycosyl transferase, family 2
BKK81_RS06795	COG0583	DNA-binding transcription factor activity
BKK81_RS06800	COG2223	nitrite transmembrane transporter activity
BKK81_RS06815	COG1704	LemA family
BKK81_RS06820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKK81_RS06825	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BKK81_RS06830	COG1773	rubredoxin
BKK81_RS06855	COG0643	Histidine kinase
BKK81_RS06855	COG2198	Histidine kinase
BKK81_RS06860	COG2271	Major facilitator Superfamily
BKK81_RS06880	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BKK81_RS06885	COG3038	cytochrome b561
BKK81_RS06900	COG0347	Belongs to the P(II) protein family
BKK81_RS06905	COG2860	membrane
BKK81_RS06910	COG2840	Smr protein MutS2
BKK81_RS06915	COG0492	ferredoxin-NADP+ reductase activity
BKK81_RS06920	COG1674	ftsk spoiiie
BKK81_RS06925	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BKK81_RS06945	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BKK81_RS06950	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BKK81_RS06965	COG1253	flavin adenine dinucleotide binding
BKK81_RS06970	COG0583	DNA-binding transcription factor activity
BKK81_RS06980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKK81_RS06985	COG0765	amino acid transport
BKK81_RS06990	COG1181	Belongs to the D-alanine--D-alanine ligase family
BKK81_RS06990	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BKK81_RS06995	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BKK81_RS06995	COG0189	ligase activity
BKK81_RS07000	COG1132	(ABC) transporter
BKK81_RS07025	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BKK81_RS07045	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BKK81_RS07055	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BKK81_RS07060	COG0287	Prephenate dehydrogenase
BKK81_RS07065	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BKK81_RS07075	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BKK81_RS07085	COG0776	regulation of translation
BKK81_RS07095	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BKK81_RS07105	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BKK81_RS07110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKK81_RS07120	COG2233	PERMEase
BKK81_RS07130	COG2951	lytic endotransglycosylase activity
BKK81_RS07145	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BKK81_RS07150	COG2011	ABC-type metal ion transport system permease component
BKK81_RS07155	COG1464	Belongs to the NlpA lipoprotein family
BKK81_RS07170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKK81_RS07200	COG0228	four-way junction DNA binding
BKK81_RS07205	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BKK81_RS07210	COG0336	Belongs to the RNA methyltransferase TrmD family
BKK81_RS07215	COG0335	large ribosomal subunit rRNA binding
BKK81_RS07225	COG1054	Belongs to the UPF0176 family
BKK81_RS07235	COG0859	PFAM glycosyl transferase family 9
BKK81_RS07240	COG3307	-O-antigen
BKK81_RS07255	COG1216	Glycosyl transferase, family 2
BKK81_RS07265	COG1132	(ABC) transporter
BKK81_RS07290	COG0424	maF-like protein
BKK81_RS07295	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BKK81_RS07300	COG0799	negative regulation of ribosome biogenesis
BKK81_RS07305	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BKK81_RS07310	COG0408	coproporphyrinogen oxidase activity
BKK81_RS07315	COG0151	Belongs to the GarS family
BKK81_RS07320	COG0217	transcriptional regulatory protein
BKK81_RS07325	COG0433	COG0433 Predicted ATPase
BKK81_RS07335	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BKK81_RS07340	COG0477	Major facilitator Superfamily
BKK81_RS07345	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BKK81_RS07345	COG2010	Cytochrome c
BKK81_RS07350	COG2080	2 iron, 2 sulfur cluster binding
BKK81_RS07355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKK81_RS07360	COG3473	Maleate cis-trans isomerase
BKK81_RS07365	COG0596	Alpha beta hydrolase
BKK81_RS07370	COG2309	aminopeptidase activity
BKK81_RS07375	COG1335	isochorismatase
BKK81_RS07380	COG2010	Cytochrome c
BKK81_RS07380	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BKK81_RS07385	COG1846	Transcriptional regulator
BKK81_RS07395	COG0697	spore germination
BKK81_RS07400	COG1028	Short-chain dehydrogenase reductase Sdr
BKK81_RS07405	COG1803	Methylglyoxal synthase
BKK81_RS07430	COG4603	Belongs to the binding-protein-dependent transport system permease family
BKK81_RS07435	COG3845	ABC transporter
BKK81_RS07470	COG2186	Transcriptional regulator
BKK81_RS07480	COG3181	Tripartite tricarboxylate transporter family receptor
BKK81_RS07500	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BKK81_RS07505	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BKK81_RS07510	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BKK81_RS07520	COG0515	serine threonine protein kinase
BKK81_RS07525	COG1561	YicC-like family, N-terminal region
BKK81_RS07530	COG0194	GDP metabolic process
BKK81_RS07535	COG1758	RNA polymerase activity
BKK81_RS07540	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BKK81_RS07565	COG3128	pkhd-type hydroxylase
BKK81_RS07585	COG3042	response to heat
BKK81_RS07590	COG3447	MASE1 domain protein
BKK81_RS07590	COG5001	Diguanylate cyclase
BKK81_RS07590	COG5002	protein histidine kinase activity
BKK81_RS07595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKK81_RS07605	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BKK81_RS07670	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BKK81_RS07675	COG0308	aminopeptidase N
BKK81_RS07685	COG0281	malic enzyme
BKK81_RS07685	COG0280	phosphate acetyltransferase
BKK81_RS07705	COG0596	Alpha beta hydrolase
BKK81_RS07710	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BKK81_RS07725	COG2233	PERMEase
BKK81_RS07735	COG2351	hydroxyisourate hydrolase activity
BKK81_RS07750	COG2119	membrane
BKK81_RS07760	COG0402	S-adenosylhomocysteine deaminase activity
BKK81_RS07765	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BKK81_RS07770	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BKK81_RS07770	COG3608	succinylglutamate desuccinylase aspartoacylase
BKK81_RS07775	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BKK81_RS07795	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BKK81_RS07825	COG0438	transferase activity, transferring glycosyl groups
BKK81_RS07860	COG0028	Belongs to the TPP enzyme family
BKK81_RS07865	COG0440	acetolactate synthase activity
BKK81_RS07870	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BKK81_RS07875	COG0688	phosphatidylethanolamine metabolic process
BKK81_RS07880	COG1183	phosphatidylcholine synthase activity
BKK81_RS07885	COG1652	LysM domain
BKK81_RS07890	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKK81_RS07900	COG0683	leucine binding
BKK81_RS07905	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BKK81_RS07910	COG1185	polyribonucleotide nucleotidyltransferase activity
BKK81_RS07915	COG3321	synthase
BKK81_RS07915	COG0604	alcohol dehydrogenase
BKK81_RS07915	COG1028	Short-chain dehydrogenase reductase Sdr
BKK81_RS07920	COG0149	triose-phosphate isomerase activity
BKK81_RS07935	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKK81_RS07940	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKK81_RS07945	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKK81_RS07950	COG0649	NAD binding
BKK81_RS07965	COG1034	ATP synthesis coupled electron transport
BKK81_RS07970	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BKK81_RS07975	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKK81_RS07985	COG0713	ATP synthesis coupled electron transport
BKK81_RS08000	COG1007	ATP synthesis coupled electron transport
BKK81_RS08015	COG1024	Enoyl-CoA hydratase
BKK81_RS08025	COG0183	Belongs to the thiolase family
BKK81_RS08040	COG0583	DNA-binding transcription factor activity
BKK81_RS08045	COG1024	Enoyl-CoA hydratase
BKK81_RS08055	COG1960	acyl-CoA dehydrogenase activity
BKK81_RS08070	COG1960	acyl-CoA dehydrogenase activity
BKK81_RS08095	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BKK81_RS08110	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BKK81_RS08140	COG0829	nickel cation binding
BKK81_RS08145	COG0831	urea catabolic process
BKK81_RS08155	COG0832	Belongs to the urease beta subunit family
BKK81_RS08160	COG0804	urea catabolic process
BKK81_RS08165	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BKK81_RS08170	COG0830	nickel cation binding
BKK81_RS08175	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BKK81_RS08195	COG0625	glutathione transferase activity
BKK81_RS08200	COG1960	acyl-CoA dehydrogenase activity
BKK81_RS08215	COG0583	DNA-binding transcription factor activity
BKK81_RS08220	COG3181	Tripartite tricarboxylate transporter family receptor
BKK81_RS08245	COG0625	glutathione transferase activity
BKK81_RS08270	COG1024	Enoyl-CoA hydratase
BKK81_RS08275	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKK81_RS08280	COG0625	glutathione transferase activity
BKK81_RS08300	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKK81_RS08305	COG1960	acyl-CoA dehydrogenase activity
BKK81_RS08315	COG1024	Enoyl-CoA hydratase
BKK81_RS08345	COG1022	Amp-dependent synthetase and ligase
BKK81_RS08360	COG0318	PFAM AMP-dependent synthetase and ligase
BKK81_RS08370	COG0318	PFAM AMP-dependent synthetase and ligase
BKK81_RS08375	COG1960	acyl-CoA dehydrogenase activity
BKK81_RS08385	COG0436	Aminotransferase
BKK81_RS08395	COG3022	response to hydroperoxide
BKK81_RS08400	COG2866	Carboxypeptidase
BKK81_RS08415	COG3181	Tripartite tricarboxylate transporter family receptor
BKK81_RS08420	COG0583	DNA-binding transcription factor activity
BKK81_RS08460	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BKK81_RS08475	COG0312	modulator of DNA gyrase
BKK81_RS08480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BKK81_RS08490	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BKK81_RS08500	COG1404	Belongs to the peptidase S8 family
BKK81_RS08515	COG0497	DNA recombination
BKK81_RS08520	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BKK81_RS08525	COG1420	regulation of RNA biosynthetic process
BKK81_RS08530	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BKK81_RS08545	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BKK81_RS08570	COG0778	Nitroreductase
BKK81_RS08575	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BKK81_RS08580	COG2878	Part of a membrane complex involved in electron transport
BKK81_RS08585	COG1309	transcriptional regulator
BKK81_RS08600	COG0556	nucleotide-excision repair
BKK81_RS08605	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BKK81_RS08620	COG1104	cysteine desulfurase activity
BKK81_RS08625	COG0822	iron-sulfur transferase activity
BKK81_RS08630	COG0316	Belongs to the HesB IscA family
BKK81_RS08635	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BKK81_RS08640	COG0443	Heat shock 70 kDa protein
BKK81_RS08655	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BKK81_RS08660	COG1028	Short-chain dehydrogenase reductase Sdr
BKK81_RS08665	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BKK81_RS08670	COG1388	LysM domain
BKK81_RS08670	COG4942	peptidase
BKK81_RS08675	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BKK81_RS08690	COG1136	(ABC) transporter
BKK81_RS08695	COG0084	hydrolase, TatD family'
BKK81_RS08715	COG3265	gluconokinase activity
BKK81_RS08720	COG2308	Evidence 4 Homologs of previously reported genes of
BKK81_RS08740	COG2267	carboxylic ester hydrolase activity
BKK81_RS08745	COG0504	CTP synthase activity
BKK81_RS08750	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BKK81_RS08760	COG0148	phosphopyruvate hydratase activity
BKK81_RS08765	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BKK81_RS08775	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BKK81_RS08785	COG2833	Protein of unknown function (DUF455)
BKK81_RS08790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKK81_RS08795	COG2267	carboxylic ester hydrolase activity
BKK81_RS08800	COG0492	ferredoxin-NADP+ reductase activity
BKK81_RS08805	COG0613	PHP domain protein
BKK81_RS08810	COG0009	L-threonylcarbamoyladenylate synthase
BKK81_RS08815	COG1994	Peptidase M50
BKK81_RS08820	COG0180	Tryptophanyl-tRNA synthetase
BKK81_RS08825	COG0275	rRNA processing
BKK81_RS08830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKK81_RS08835	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BKK81_RS08840	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BKK81_RS08845	COG2850	peptidyl-arginine hydroxylation
BKK81_RS08860	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BKK81_RS08870	COG0840	transmembrane signaling receptor activity
BKK81_RS08875	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BKK81_RS08915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKK81_RS08925	COG0483	inositol monophosphate 1-phosphatase activity
BKK81_RS08940	COG1045	serine acetyltransferase
BKK81_RS08950	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BKK81_RS08970	COG0215	cysteine-tRNA ligase activity
BKK81_RS08975	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BKK81_RS08980	COG0825	malonyl-CoA metabolic process
BKK81_RS08985	COG0037	tRNA processing
BKK81_RS08990	COG0527	aspartate kinase activity
BKK81_RS09000	COG3384	dioxygenase
BKK81_RS09020	COG1028	Short-chain dehydrogenase reductase Sdr
BKK81_RS09040	COG3384	dioxygenase
BKK81_RS09130	COG2204	response regulator
BKK81_RS09165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKK81_RS09170	COG2271	Major facilitator Superfamily
BKK81_RS09175	COG5002	protein histidine kinase activity
BKK81_RS09180	COG0745	RESPONSE REGULATOR receiver
BKK81_RS09185	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKK81_RS09195	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKK81_RS09210	COG4191	Histidine kinase
BKK81_RS09225	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BKK81_RS09245	COG4566	intracellular signal transduction
BKK81_RS09285	COG1840	ABC-type Fe3 transport system, periplasmic component
BKK81_RS09300	COG3842	ATPase activity
BKK81_RS09305	COG0583	DNA-binding transcription factor activity
BKK81_RS09340	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BKK81_RS09345	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BKK81_RS09350	COG0277	FAD linked oxidase domain protein
BKK81_RS09365	COG1295	ribonuclease BN
BKK81_RS09390	COG0477	Major facilitator Superfamily
BKK81_RS09400	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BKK81_RS09405	COG2814	Major facilitator Superfamily
BKK81_RS09410	COG0579	oxidoreductase
BKK81_RS09415	COG2186	Transcriptional regulator
BKK81_RS09425	COG0180	Tryptophanyl-tRNA synthetase
BKK81_RS09440	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BKK81_RS09470	COG1028	Short-chain dehydrogenase reductase Sdr
BKK81_RS09485	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BKK81_RS09535	COG2814	Major facilitator Superfamily
BKK81_RS09545	COG1214	PFAM Peptidase M22, glycoprotease
BKK81_RS09555	COG1573	uracil-dna glycosylase
BKK81_RS09565	COG0477	Major facilitator Superfamily
BKK81_RS09570	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BKK81_RS09585	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BKK81_RS09590	COG0488	(ABC) transporter
BKK81_RS09605	COG2890	protein-(glutamine-N5) methyltransferase activity
BKK81_RS09610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKK81_RS09615	COG1393	Belongs to the ArsC family
BKK81_RS09625	COG2171	N-acyltransferase activity
BKK81_RS09630	COG0436	Aminotransferase
BKK81_RS09655	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BKK81_RS09660	COG0242	peptide deformylase activity
BKK81_RS09670	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BKK81_RS09670	COG2169	Transcriptional regulator
BKK81_RS09690	COG5265	(ABC) transporter
BKK81_RS09710	COG0417	DNA replication proofreading
BKK81_RS09715	COG0417	DNA replication proofreading
BKK81_RS09720	COG1187	pseudouridine synthase activity
BKK81_RS09725	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BKK81_RS09735	COG0052	Belongs to the universal ribosomal protein uS2 family
BKK81_RS09740	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BKK81_RS09745	COG0528	UMP kinase activity
BKK81_RS09750	COG0233	cytoplasmic translational termination
BKK81_RS09755	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BKK81_RS09760	COG0575	Belongs to the CDS family
BKK81_RS09765	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BKK81_RS09770	COG0750	zinc metalloprotease
BKK81_RS09785	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BKK81_RS09790	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BKK81_RS09795	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BKK81_RS09800	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BKK81_RS09805	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BKK81_RS09810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BKK81_RS09815	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BKK81_RS09830	COG0330	HflC and HflK could
BKK81_RS09835	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BKK81_RS09840	COG2867	negative regulation of translational initiation
BKK81_RS09845	COG2914	Belongs to the UPF0125 (RnfH) family
BKK81_RS09870	COG0519	Catalyzes the synthesis of GMP from XMP
BKK81_RS09870	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BKK81_RS09880	COG1280	lysine exporter protein (LysE YggA)
BKK81_RS09915	COG3268	Saccharopine dehydrogenase
BKK81_RS09920	COG0318	PFAM AMP-dependent synthetase and ligase
BKK81_RS09925	COG2909	trisaccharide binding
BKK81_RS09930	COG3284	Transcriptional regulator
BKK81_RS09935	COG4647	ligase activity
BKK81_RS09940	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
BKK81_RS09945	COG0145	ligase activity
BKK81_RS09950	COG0183	Belongs to the thiolase family
BKK81_RS09975	COG4221	oxidoreductase activity
BKK81_RS09985	COG3447	MASE1 domain protein
BKK81_RS09985	COG5002	protein histidine kinase activity
BKK81_RS09985	COG5001	Diguanylate cyclase
BKK81_RS09990	COG0840	transmembrane signaling receptor activity
BKK81_RS10005	COG2200	EAL domain
BKK81_RS10005	COG2199	diguanylate cyclase activity
BKK81_RS10005	COG2202	Pas domain
BKK81_RS10035	COG0602	queuosine metabolic process
BKK81_RS10040	COG0720	synthase
BKK81_RS10050	COG1619	proteins homologs of microcin C7 resistance protein MccF
BKK81_RS10055	COG0488	(ABC) transporter
BKK81_RS10145	COG3829	transcription factor binding
BKK81_RS10170	COG0589	response to stress
BKK81_RS10175	COG1028	Short-chain dehydrogenase reductase Sdr
BKK81_RS10190	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BKK81_RS10210	COG3706	GGDEF domain
BKK81_RS10210	COG2203	Gaf domain
BKK81_RS10210	COG5001	Diguanylate cyclase
BKK81_RS10210	COG4251	negative regulation of phosphorylation
BKK81_RS10215	COG2308	Evidence 4 Homologs of previously reported genes of
BKK81_RS10240	COG1305	Transglutaminase-like
BKK81_RS10245	COG0859	PFAM glycosyl transferase family 9
BKK81_RS10275	COG0583	DNA-binding transcription factor activity
BKK81_RS10285	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKK81_RS10295	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKK81_RS10325	COG1294	oxidase, subunit
BKK81_RS10340	COG0583	DNA-binding transcription factor activity
BKK81_RS10355	COG0656	L-ascorbic acid biosynthetic process
BKK81_RS10360	COG1902	pentaerythritol trinitrate reductase activity
BKK81_RS10375	COG1902	pentaerythritol trinitrate reductase activity
BKK81_RS10410	COG3706	GGDEF domain
BKK81_RS10415	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKK81_RS10435	COG0583	DNA-binding transcription factor activity
BKK81_RS10440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKK81_RS10570	COG0431	NADPH-dependent FMN reductase
BKK81_RS10590	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKK81_RS10615	COG3829	transcription factor binding
BKK81_RS10620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKK81_RS10655	COG0583	DNA-binding transcription factor activity
BKK81_RS10660	COG3038	cytochrome b561
BKK81_RS10675	COG0517	IMP dehydrogenase activity
BKK81_RS10675	COG0516	GMP reductase activity
BKK81_RS10700	COG1309	transcriptional regulator
BKK81_RS10705	COG0493	'glutamate synthase
BKK81_RS10705	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BKK81_RS10730	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BKK81_RS10740	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BKK81_RS10750	COG1090	epimerase
BKK81_RS10755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKK81_RS10785	COG1657	PFAM Prenyltransferase squalene oxidase
BKK81_RS10790	COG1309	transcriptional regulator
BKK81_RS10835	COG0840	transmembrane signaling receptor activity
BKK81_RS10855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKK81_RS10870	COG2072	flavoprotein involved in K transport
BKK81_RS10875	COG0601	transmembrane transport
BKK81_RS10880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKK81_RS10895	COG0747	negative chemotaxis
BKK81_RS10925	COG1674	ftsk spoiiie
BKK81_RS10930	COG2203	Gaf domain
BKK81_RS10930	COG3706	GGDEF domain
BKK81_RS10930	COG4251	negative regulation of phosphorylation
BKK81_RS10930	COG5001	Diguanylate cyclase
BKK81_RS10955	COG0583	DNA-binding transcription factor activity
BKK81_RS10960	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BKK81_RS10965	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BKK81_RS10975	COG0084	hydrolase, TatD family'
BKK81_RS10990	COG0470	DNA polymerase III
BKK81_RS10995	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BKK81_RS11000	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BKK81_RS11040	COG0657	acetylesterase activity
BKK81_RS11045	COG0459	protein refolding
BKK81_RS11050	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BKK81_RS11060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKK81_RS11075	COG0277	FAD linked oxidase domain protein
BKK81_RS11080	COG0436	Aminotransferase
BKK81_RS11085	COG0765	amino acid transport
BKK81_RS11090	COG0765	amino acid transport
BKK81_RS11095	COG1126	abc transporter atp-binding protein
BKK81_RS11110	COG2072	flavoprotein involved in K transport
BKK81_RS11120	COG3608	succinylglutamate desuccinylase aspartoacylase
BKK81_RS11130	COG1454	alcohol dehydrogenase
BKK81_RS11150	COG1794	racemase activity, acting on amino acids and derivatives
BKK81_RS11160	COG0596	Alpha beta hydrolase
BKK81_RS11175	COG4221	oxidoreductase activity
BKK81_RS11185	COG2130	NADP-dependent
BKK81_RS11205	COG1960	acyl-CoA dehydrogenase activity
BKK81_RS11215	COG0183	Belongs to the thiolase family
BKK81_RS11220	COG1335	isochorismatase
BKK81_RS11225	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKK81_RS11225	COG1024	Enoyl-CoA hydratase
BKK81_RS11230	COG0833	amino acid
BKK81_RS11240	COG0410	ABC transporter
BKK81_RS11245	COG0411	ABC transporter
BKK81_RS11265	COG0318	PFAM AMP-dependent synthetase and ligase
BKK81_RS11270	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BKK81_RS11275	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKK81_RS11280	COG2917	probably involved in intracellular septation
BKK81_RS11285	COG0271	Belongs to the BolA IbaG family
BKK81_RS11290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKK81_RS11295	COG2200	EAL domain
BKK81_RS11300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKK81_RS11300	COG2205	protein histidine kinase activity
BKK81_RS11305	COG2197	response regulator
BKK81_RS11325	COG3188	usher protein
BKK81_RS11330	COG3121	Chaperone
BKK81_RS11350	COG0047	phosphoribosylformylglycinamidine synthase activity
BKK81_RS11350	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BKK81_RS11375	COG0166	Belongs to the GPI family
BKK81_RS11380	COG4181	ATPase activity
BKK81_RS11390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKK81_RS11410	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BKK81_RS11415	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BKK81_RS11420	COG0740	serine-type endopeptidase activity
BKK81_RS11425	COG0544	peptidyl-prolyl cis-trans isomerase activity
BKK81_RS11430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKK81_RS11430	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BKK81_RS11435	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BKK81_RS11545	COG0747	negative chemotaxis
BKK81_RS11550	COG0601	transmembrane transport
BKK81_RS11555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKK81_RS11560	COG4608	Belongs to the ABC transporter superfamily
BKK81_RS11565	COG0444	Belongs to the ABC transporter superfamily
BKK81_RS11570	COG0154	amidase activity
BKK81_RS11575	COG1773	rubredoxin
BKK81_RS11605	COG0583	DNA-binding transcription factor activity
BKK81_RS11615	COG2175	clavaminate synthase activity
BKK81_RS11625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKK81_RS11630	COG1562	ergosterol biosynthetic process
BKK81_RS11660	COG0450	alkyl hydroperoxide reductase
BKK81_RS11665	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKK81_RS11675	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BKK81_RS11680	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BKK81_RS11685	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BKK81_RS11690	COG3622	Belongs to the hyi family
BKK81_RS11710	COG1473	amidohydrolase
BKK81_RS11755	COG0488	(ABC) transporter
BKK81_RS11780	COG1012	belongs to the aldehyde dehydrogenase family
BKK81_RS11790	COG2271	Major facilitator Superfamily
BKK81_RS11795	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BKK81_RS11800	COG0583	DNA-binding transcription factor activity
BKK81_RS11815	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BKK81_RS11875	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
BKK81_RS11890	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKK81_RS11900	COG1881	PFAM PEBP family protein
BKK81_RS11905	COG2207	Transcriptional regulator
BKK81_RS11935	COG1309	transcriptional regulator
BKK81_RS11960	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BKK81_RS11970	COG0702	epimerase
BKK81_RS11975	COG2824	Alkylphosphonate utilization operon protein PhnA
BKK81_RS12015	COG2860	membrane
BKK81_RS12020	COG0129	dihydroxy-acid dehydratase activity
BKK81_RS12025	COG3119	arylsulfatase activity
BKK81_RS12030	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BKK81_RS12035	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
BKK81_RS12040	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BKK81_RS12065	COG4566	intracellular signal transduction
BKK81_RS12085	COG5001	Diguanylate cyclase
BKK81_RS12085	COG5002	protein histidine kinase activity
BKK81_RS12150	COG3179	chitinase
BKK81_RS12210	COG0582	viral genome integration into host DNA
BKK81_RS12220	COG1595	DNA-templated transcription, initiation
BKK81_RS12240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BKK81_RS12245	COG2151	metal-sulfur cluster biosynthetic enzyme
BKK81_RS12250	COG3396	Phenylacetate-CoA oxygenase
BKK81_RS12255	COG3460	Phenylacetate-CoA oxygenase
BKK81_RS12260	COG3396	Phenylacetate-CoA oxygenase
BKK81_RS12265	COG3327	negative regulation of DNA-templated transcription, initiation
BKK81_RS12270	COG0165	Argininosuccinate lyase
BKK81_RS12275	COG3530	Putative quorum-sensing-regulated virulence factor
BKK81_RS12280	COG0583	DNA-binding transcription factor activity
BKK81_RS12285	COG4336	lyase activity
BKK81_RS12290	COG2814	Major facilitator Superfamily
BKK81_RS12300	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BKK81_RS12305	COG4770	biotin carboxylase activity
BKK81_RS12355	COG3119	arylsulfatase activity
BKK81_RS12385	COG1902	pentaerythritol trinitrate reductase activity
BKK81_RS12390	COG0697	spore germination
BKK81_RS12400	COG4977	sequence-specific DNA binding
BKK81_RS12410	COG0697	spore germination
BKK81_RS12415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKK81_RS12420	COG0251	oxidation-reduction process
BKK81_RS12435	COG0129	dihydroxy-acid dehydratase activity
BKK81_RS12455	COG2199	diguanylate cyclase activity
BKK81_RS12455	COG2203	Gaf domain
BKK81_RS12465	COG3706	GGDEF domain
BKK81_RS12470	COG0560	Phosphoserine phosphatase
BKK81_RS12490	COG0626	cystathionine gamma-synthase activity
BKK81_RS12500	COG0183	Belongs to the thiolase family
BKK81_RS12505	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BKK81_RS12525	COG3209	COG3209 Rhs family protein
BKK81_RS12600	COG3829	transcription factor binding
BKK81_RS12640	COG1028	Short-chain dehydrogenase reductase Sdr
BKK81_RS12645	COG0183	Belongs to the thiolase family
BKK81_RS12650	COG3243	poly(R)-hydroxyalkanoic acid synthase
BKK81_RS12665	COG0564	pseudouridine synthase activity
BKK81_RS12675	COG1199	ATP-dependent helicase activity
BKK81_RS12690	COG2183	response to ionizing radiation
BKK81_RS12695	COG3158	transport of potassium into the cell
BKK81_RS12715	COG0411	ABC transporter
BKK81_RS12720	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKK81_RS12760	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BKK81_RS12765	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BKK81_RS12770	COG0167	dihydroorotate dehydrogenase activity
BKK81_RS12775	COG0667	Aldo Keto reductase
BKK81_RS12790	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BKK81_RS12810	COG1414	Transcriptional regulator
BKK81_RS12820	COG2186	Transcriptional regulator
BKK81_RS12840	COG0824	Thioesterase
BKK81_RS12850	COG0123	including yeast histone deacetylase and acetoin utilization protein
BKK81_RS12865	COG3121	Chaperone
BKK81_RS12870	COG3188	usher protein
BKK81_RS12875	COG3121	Chaperone
BKK81_RS12890	COG2197	response regulator
BKK81_RS12895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKK81_RS12905	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKK81_RS12910	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BKK81_RS12920	COG4566	intracellular signal transduction
BKK81_RS12935	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BKK81_RS12940	COG0339	signal peptide processing
BKK81_RS12995	COG3181	Tripartite tricarboxylate transporter family receptor
BKK81_RS13005	COG0427	acetyl-CoA hydrolase
BKK81_RS13015	COG2902	Dehydrogenase
BKK81_RS13025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKK81_RS13030	COG3181	Tripartite tricarboxylate transporter family receptor
BKK81_RS13035	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BKK81_RS13085	COG0776	regulation of translation
BKK81_RS13090	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKK81_RS13090	COG0072	phenylalanine-tRNA ligase activity
BKK81_RS13095	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BKK81_RS13100	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BKK81_RS13105	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BKK81_RS13110	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BKK81_RS13115	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BKK81_RS13130	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BKK81_RS13135	COG0251	oxidation-reduction process
BKK81_RS13145	COG1028	Short-chain dehydrogenase reductase Sdr
BKK81_RS13155	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BKK81_RS13165	COG0583	DNA-binding transcription factor activity
BKK81_RS13175	COG0501	Belongs to the peptidase M48B family
BKK81_RS13180	COG2224	Isocitrate lyase
BKK81_RS13195	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BKK81_RS13200	COG0028	Belongs to the TPP enzyme family
BKK81_RS13205	COG3279	Response regulator of the LytR AlgR family
BKK81_RS13210	COG2972	Histidine kinase
BKK81_RS13225	COG0583	DNA-binding transcription factor activity
BKK81_RS13230	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BKK81_RS13235	COG4208	sulfate ABC transporter
BKK81_RS13260	COG1116	anion transmembrane transporter activity
BKK81_RS13265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKK81_RS13270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKK81_RS13275	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKK81_RS13280	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BKK81_RS13290	COG0542	response to heat
BKK81_RS13305	COG0559	Belongs to the binding-protein-dependent transport system permease family
BKK81_RS13310	COG4177	L-phenylalanine transmembrane transporter activity
BKK81_RS13330	COG1309	transcriptional regulator
BKK81_RS13340	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BKK81_RS13345	COG0314	molybdopterin synthase activity
BKK81_RS13355	COG0303	'Molybdopterin
BKK81_RS13370	COG0436	Aminotransferase
BKK81_RS13380	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BKK81_RS13385	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BKK81_RS13395	COG0791	NLP P60 protein
BKK81_RS13400	COG0306	phosphate transporter
BKK81_RS13410	COG0305	Participates in initiation and elongation during chromosome replication
BKK81_RS13415	COG0359	binds to the 23S rRNA
BKK81_RS13420	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BKK81_RS13430	COG0360	Binds together with S18 to 16S ribosomal RNA
BKK81_RS13435	COG0252	asparaginase activity
BKK81_RS13440	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BKK81_RS13445	COG3706	GGDEF domain
BKK81_RS13465	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BKK81_RS13470	COG0431	NADPH-dependent FMN reductase
BKK81_RS13475	COG1024	Enoyl-CoA hydratase
BKK81_RS13480	COG0840	transmembrane signaling receptor activity
BKK81_RS13505	COG1566	PFAM secretion protein HlyD family protein
BKK81_RS13510	COG2814	Major facilitator Superfamily
BKK81_RS13525	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BKK81_RS13530	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BKK81_RS13535	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BKK81_RS13540	COG2251	uridine kinase activity
BKK81_RS13540	COG0195	Participates in both transcription termination and antitermination
BKK81_RS13545	COG0779	Required for maturation of 30S ribosomal subunits
BKK81_RS13550	COG1187	pseudouridine synthase activity
BKK81_RS13555	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BKK81_RS13565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKK81_RS13600	COG3278	Belongs to the heme-copper respiratory oxidase family
BKK81_RS13610	COG2217	Heavy metal translocating P-type atpase
BKK81_RS13615	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BKK81_RS13620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKK81_RS13625	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKK81_RS13630	COG0567	Dehydrogenase, E1 component
BKK81_RS13635	COG0584	glycerophosphoryl diester phosphodiesterase
BKK81_RS13640	COG3842	ATPase activity
BKK81_RS13650	COG1175	transmembrane transport
BKK81_RS13655	COG1653	transport
BKK81_RS13680	COG0174	glutamine synthetase
BKK81_RS13715	COG1643	Atp-dependent helicase
BKK81_RS13720	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BKK81_RS13720	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BKK81_RS13725	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BKK81_RS13735	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BKK81_RS13740	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BKK81_RS13750	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BKK81_RS13760	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BKK81_RS13765	COG0557	exoribonuclease II activity
BKK81_RS13780	COG2910	NAD(P)H-binding
BKK81_RS13785	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BKK81_RS13790	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BKK81_RS13795	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BKK81_RS13800	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BKK81_RS13805	COG0330	HflC and HflK could
BKK81_RS13810	COG0330	HflC and HflK could
BKK81_RS13815	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BKK81_RS13820	COG1923	regulation of RNA biosynthetic process
BKK81_RS13825	COG1160	GTP binding
BKK81_RS13840	COG0124	histidyl-tRNA synthetase
BKK81_RS13845	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BKK81_RS13860	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BKK81_RS13865	COG0105	UTP biosynthetic process
BKK81_RS13870	COG0670	Belongs to the BI1 family
BKK81_RS13875	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BKK81_RS13900	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BKK81_RS13905	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BKK81_RS13910	COG1028	Short-chain dehydrogenase reductase Sdr
BKK81_RS13910	COG3321	synthase
BKK81_RS13910	COG0604	alcohol dehydrogenase
BKK81_RS13915	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BKK81_RS13935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKK81_RS13945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKK81_RS13955	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKK81_RS13960	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKK81_RS13970	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BKK81_RS13975	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BKK81_RS13980	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BKK81_RS13995	COG1074	ATP-dependent DNA helicase activity
BKK81_RS14015	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BKK81_RS14025	COG0254	rRNA binding
BKK81_RS14035	COG0534	Mate efflux family protein
BKK81_RS14055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BKK81_RS14060	COG1752	Esterase of the alpha-beta hydrolase superfamily
BKK81_RS14065	COG0791	NLP P60 protein
BKK81_RS14070	COG4172	Belongs to the ABC transporter superfamily
BKK81_RS14075	COG4239	(ABC) transporter, permease
BKK81_RS14080	COG4174	ABC transporter (Permease)
BKK81_RS14115	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BKK81_RS14120	COG2062	phosphohistidine phosphatase, SixA
BKK81_RS14130	COG0248	Ppx GppA phosphatase
BKK81_RS14135	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BKK81_RS14155	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BKK81_RS14160	COG0581	inorganic phosphate transmembrane transporter activity
BKK81_RS14170	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BKK81_RS14175	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BKK81_RS14185	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKK81_RS14190	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BKK81_RS14195	COG1534	Rna-binding protein
BKK81_RS14205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BKK81_RS14210	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BKK81_RS14220	COG0505	Belongs to the CarA family
BKK81_RS14245	COG1024	Enoyl-CoA hydratase
BKK81_RS14250	COG1028	Short-chain dehydrogenase reductase Sdr
BKK81_RS14260	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKK81_RS14265	COG1388	LysM domain
BKK81_RS14265	COG0741	lytic transglycosylase activity
BKK81_RS14270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKK81_RS14275	COG2226	methyltransferase
BKK81_RS14280	COG0328	RNA-DNA hybrid ribonuclease activity
BKK81_RS14295	COG1335	isochorismatase
BKK81_RS14320	COG0395	ABC-type sugar transport system, permease component
BKK81_RS14330	COG3842	ATPase activity
BKK81_RS14335	COG3842	ATPase activity
BKK81_RS14355	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BKK81_RS14360	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BKK81_RS14365	COG3895	Periplasmic Protein
BKK81_RS14385	COG2205	protein histidine kinase activity
BKK81_RS14385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKK81_RS14395	COG2199	diguanylate cyclase activity
BKK81_RS14415	COG2202	Pas domain
BKK81_RS14415	COG2199	diguanylate cyclase activity
BKK81_RS14415	COG2200	EAL domain
BKK81_RS14425	COG0450	alkyl hydroperoxide reductase
BKK81_RS14450	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKK81_RS14455	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKK81_RS14465	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BKK81_RS14470	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BKK81_RS14495	COG3193	protein, possibly involved in utilization of glycolate and propanediol
BKK81_RS14515	COG2855	membrane
BKK81_RS14520	COG0583	DNA-binding transcription factor activity
BKK81_RS14525	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BKK81_RS14525	COG4651	solute:proton antiporter activity
BKK81_RS14550	COG0322	excinuclease ABC activity
BKK81_RS14560	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BKK81_RS14570	COG0736	holo-[acyl-carrier-protein] synthase activity
BKK81_RS14575	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BKK81_RS14580	COG1381	Involved in DNA repair and RecF pathway recombination
BKK81_RS14585	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BKK81_RS14590	COG0571	ribonuclease III activity
BKK81_RS14600	COG0681	Belongs to the peptidase S26 family
BKK81_RS14605	COG0481	GTPase activity
BKK81_RS14615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKK81_RS14640	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BKK81_RS14645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKK81_RS14655	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BKK81_RS14660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKK81_RS14665	COG0416	fatty acid biosynthetic process
BKK81_RS14670	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BKK81_RS14675	COG1399	metal-binding, possibly nucleic acid-binding protein
BKK81_RS14680	COG0424	maF-like protein
BKK81_RS14710	COG1530	ribonuclease E activity
BKK81_RS14715	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BKK81_RS14720	COG0746	molybdenum cofactor guanylyltransferase activity
BKK81_RS14735	COG1322	Protein conserved in bacteria
BKK81_RS14755	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BKK81_RS14770	COG0492	ferredoxin-NADP+ reductase activity
BKK81_RS14785	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BKK81_RS14795	COG1131	(ABC) transporter
BKK81_RS14830	COG0285	dihydrofolate synthase activity
BKK81_RS14835	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BKK81_RS14840	COG0159	tryptophan synthase activity
BKK81_RS14845	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BKK81_RS14850	COG0133	tryptophan synthase activity
BKK81_RS14855	COG0135	phosphoribosylanthranilate isomerase activity
BKK81_RS14860	COG0101	tRNA pseudouridine synthase activity
BKK81_RS14870	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BKK81_RS14875	COG0473	3-isopropylmalate dehydrogenase activity
BKK81_RS14880	COG0066	3-isopropylmalate dehydratase activity
BKK81_RS14890	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BKK81_RS14920	COG0372	Belongs to the citrate synthase family
BKK81_RS14925	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BKK81_RS14930	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BKK81_RS14935	COG1053	succinate dehydrogenase
BKK81_RS14940	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BKK81_RS14955	COG0039	L-malate dehydrogenase activity
BKK81_RS14980	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BKK81_RS14990	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BKK81_RS14995	COG0747	negative chemotaxis
BKK81_RS15020	COG0326	Molecular chaperone. Has ATPase activity
BKK81_RS15025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKK81_RS15035	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BKK81_RS15055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKK81_RS15060	COG0625	glutathione transferase activity
BKK81_RS15065	COG1620	l-lactate permease
BKK81_RS15085	COG1132	(ABC) transporter
BKK81_RS15095	COG1473	amidohydrolase
BKK81_RS15100	COG0583	DNA-binding transcription factor activity
BKK81_RS15135	COG0488	(ABC) transporter
BKK81_RS15140	COG3135	benzoate transporter
BKK81_RS15155	COG2194	sulfuric ester hydrolase activity
BKK81_RS15180	COG0513	Belongs to the DEAD box helicase family
BKK81_RS15185	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BKK81_RS15190	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BKK81_RS15195	COG0861	Integral membrane protein TerC family
BKK81_RS15200	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BKK81_RS15210	COG0312	modulator of DNA gyrase
BKK81_RS15215	COG3028	Belongs to the UPF0307 family
BKK81_RS15220	COG0521	Mo-molybdopterin cofactor biosynthetic process
BKK81_RS15230	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BKK81_RS15235	COG0501	Belongs to the peptidase M48B family
BKK81_RS15240	COG1162	GTPase activity
BKK81_RS15255	COG1741	Belongs to the pirin family
BKK81_RS15260	COG0583	DNA-binding transcription factor activity
BKK81_RS15265	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BKK81_RS15275	COG0513	Belongs to the DEAD box helicase family
BKK81_RS15285	COG3181	Tripartite tricarboxylate transporter family receptor
BKK81_RS15295	COG1414	Transcriptional regulator
BKK81_RS15325	COG2081	HI0933 family
BKK81_RS15330	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BKK81_RS15335	COG1469	GTP cyclohydrolase I activity
BKK81_RS15340	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BKK81_RS15345	COG0142	geranyltranstransferase activity
BKK81_RS15350	COG1722	exodeoxyribonuclease VII activity
BKK81_RS15375	COG0412	Dienelactone hydrolase
BKK81_RS15380	COG1252	NADH dehydrogenase
BKK81_RS15385	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BKK81_RS15385	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BKK81_RS15390	COG1611	Belongs to the LOG family
BKK81_RS15400	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BKK81_RS15410	COG0330	HflC and HflK could
BKK81_RS15425	COG0477	Major facilitator Superfamily
BKK81_RS15430	COG0235	Class ii aldolase
BKK81_RS15435	COG1942	4-Oxalocrotonate Tautomerase
BKK81_RS15445	COG2816	NAD+ diphosphatase activity
BKK81_RS15450	COG0425	Belongs to the sulfur carrier protein TusA family
BKK81_RS15455	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BKK81_RS15460	COG0525	valine-tRNA ligase activity
BKK81_RS15465	COG0210	DNA helicase
BKK81_RS15470	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BKK81_RS15475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKK81_RS15490	COG3263	regulation of cellular component size
BKK81_RS15530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKK81_RS15535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BKK81_RS15555	COG4681	YaeQ
BKK81_RS15570	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BKK81_RS15575	COG0666	response to abiotic stimulus
BKK81_RS15580	COG0318	PFAM AMP-dependent synthetase and ligase
BKK81_RS15605	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BKK81_RS15610	COG2982	Protein involved in outer membrane biogenesis
BKK81_RS15615	COG0259	pyridoxamine-phosphate oxidase activity
BKK81_RS15620	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BKK81_RS15630	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKK81_RS15640	COG1960	acyl-CoA dehydrogenase activity
BKK81_RS15645	COG2267	carboxylic ester hydrolase activity
BKK81_RS15655	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BKK81_RS15665	COG1522	sequence-specific DNA binding
BKK81_RS15670	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BKK81_RS15680	COG3483	tryptophan 2,3-dioxygenase activity
BKK81_RS15690	COG1960	acyl-CoA dehydrogenase activity
BKK81_RS15695	COG0450	alkyl hydroperoxide reductase
BKK81_RS15720	COG2391	methyltransferase activity
BKK81_RS15725	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BKK81_RS15735	COG2885	chlorophyll binding
BKK81_RS15740	COG0823	Involved in the tonB-independent uptake of proteins
BKK81_RS15750	COG0848	biopolymer transport protein
BKK81_RS15760	COG0824	Thioesterase
BKK81_RS15765	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BKK81_RS15770	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BKK81_RS15805	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BKK81_RS15805	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BKK81_RS15815	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BKK81_RS15820	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BKK81_RS15825	COG0436	Aminotransferase
BKK81_RS15830	COG0741	lytic transglycosylase activity
BKK81_RS15835	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BKK81_RS15840	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKK81_RS15865	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BKK81_RS15870	COG0477	Major facilitator Superfamily
BKK81_RS15875	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BKK81_RS15880	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BKK81_RS15885	COG1845	cytochrome c oxidase, subunit III
BKK81_RS15895	COG3346	SURF1 family
BKK81_RS15900	COG1968	undecaprenyl-diphosphatase activity
BKK81_RS15930	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BKK81_RS15935	COG0425	Belongs to the sulfur carrier protein TusA family
BKK81_RS15935	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BKK81_RS15970	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BKK81_RS15975	COG0438	transferase activity, transferring glycosyl groups
BKK81_RS15985	COG0438	transferase activity, transferring glycosyl groups
BKK81_RS16020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BKK81_RS16035	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BKK81_RS16040	COG0438	transferase activity, transferring glycosyl groups
BKK81_RS16070	COG1088	dTDP-glucose 4,6-dehydratase activity
BKK81_RS16075	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BKK81_RS16090	COG0540	Belongs to the ATCase OTCase family
BKK81_RS16095	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BKK81_RS16100	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BKK81_RS16105	COG1678	Uncharacterized ACR, COG1678
BKK81_RS16110	COG1187	pseudouridine synthase activity
BKK81_RS16115	COG0415	Belongs to the DNA photolyase family
BKK81_RS16130	COG0181	hydroxymethylbilane synthase activity
BKK81_RS16135	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BKK81_RS16145	COG0165	Argininosuccinate lyase
BKK81_RS16165	COG0717	Belongs to the dCTP deaminase family
BKK81_RS16170	COG2032	superoxide dismutase activity
BKK81_RS16175	COG0489	protein tyrosine kinase activity
BKK81_RS16180	COG2885	chlorophyll binding
BKK81_RS16180	COG3047	cAMP biosynthetic process
BKK81_RS16185	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKK81_RS16185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKK81_RS16195	COG2911	Protein conserved in bacteria
BKK81_RS16210	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BKK81_RS16215	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BKK81_RS16225	COG1492	cobalamin metabolic process
BKK81_RS16235	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BKK81_RS16245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BKK81_RS16255	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BKK81_RS16260	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BKK81_RS16270	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BKK81_RS16275	COG4139	cobalamin transport
BKK81_RS16280	COG4206	TonB-dependent receptor
BKK81_RS16305	COG0730	response to heat
BKK81_RS16315	COG0318	PFAM AMP-dependent synthetase and ligase
BKK81_RS16320	COG1024	Enoyl-CoA hydratase
BKK81_RS16335	COG1802	Transcriptional regulator
BKK81_RS16350	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BKK81_RS16355	COG0583	DNA-binding transcription factor activity
BKK81_RS16360	COG0129	dihydroxy-acid dehydratase activity
BKK81_RS16375	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BKK81_RS16385	COG0795	lipopolysaccharide-transporting ATPase activity
BKK81_RS16395	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BKK81_RS16395	COG1648	precorrin-2 dehydrogenase activity
BKK81_RS16400	COG2895	sulfate adenylyltransferase (ATP) activity
BKK81_RS16405	COG0175	sulfate reduction
BKK81_RS16410	COG0175	sulfate reduction
BKK81_RS16425	COG0730	response to heat
BKK81_RS16430	COG0583	DNA-binding transcription factor activity
BKK81_RS16440	COG5507	3-demethylubiquinone-9 3-methyltransferase
BKK81_RS16480	COG0402	S-adenosylhomocysteine deaminase activity
BKK81_RS16485	COG1228	amidohydrolase
BKK81_RS16495	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BKK81_RS16500	COG2188	Transcriptional regulator
BKK81_RS16510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKK81_RS16515	COG2358	TRAP transporter, solute receptor (TAXI family
BKK81_RS16530	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BKK81_RS16560	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BKK81_RS16565	COG1047	Peptidyl-prolyl cis-trans
BKK81_RS16570	COG3344	reverse transcriptase
BKK81_RS16575	COG2003	Belongs to the UPF0758 family
BKK81_RS16580	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BKK81_RS16585	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BKK81_RS16590	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BKK81_RS16600	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BKK81_RS16610	COG0668	transmembrane transport
BKK81_RS16615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BKK81_RS16620	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BKK81_RS16620	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BKK81_RS16625	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BKK81_RS16630	COG2197	response regulator
BKK81_RS16635	COG2198	Histidine kinase
BKK81_RS16635	COG0784	Response regulator, receiver
BKK81_RS16635	COG5002	protein histidine kinase activity
BKK81_RS16640	COG0196	riboflavin kinase activity
BKK81_RS16645	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BKK81_RS16650	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BKK81_RS16655	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BKK81_RS16660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKK81_RS16665	COG0756	dUTP diphosphatase activity
BKK81_RS16680	COG0542	response to heat
BKK81_RS16685	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BKK81_RS16690	COG1278	Cold shock
BKK81_RS16715	COG1666	GTP binding
BKK81_RS16720	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BKK81_RS16730	COG3123	guanosine phosphorylase activity
BKK81_RS16735	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BKK81_RS16745	COG0268	Binds directly to 16S ribosomal RNA
BKK81_RS16750	COG0728	peptidoglycan biosynthetic process
BKK81_RS16760	COG0586	Pfam SNARE associated Golgi protein
BKK81_RS16765	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BKK81_RS16770	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BKK81_RS16780	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BKK81_RS16785	COG0628	permease
BKK81_RS16790	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BKK81_RS16805	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BKK81_RS16815	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BKK81_RS16820	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BKK81_RS16835	COG0484	heat shock protein binding
BKK81_RS16840	COG0443	Heat shock 70 kDa protein
BKK81_RS16845	COG2096	Adenosyltransferase
BKK81_RS16850	COG0277	FAD linked oxidase domain protein
BKK81_RS16855	COG0583	DNA-binding transcription factor activity
BKK81_RS16860	COG0277	FAD linked oxidase domain protein
BKK81_RS16865	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKK81_RS16870	COG0277	FAD linked oxidase domain protein
BKK81_RS16875	COG0247	lactate metabolic process
BKK81_RS16880	COG1380	Effector of murein hydrolase LrgA
BKK81_RS16885	COG1346	cytolysis
BKK81_RS16900	COG0386	Belongs to the glutathione peroxidase family
BKK81_RS16925	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BKK81_RS16930	COG0783	Belongs to the Dps family
BKK81_RS16945	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BKK81_RS16950	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BKK81_RS16955	COG0343	queuine tRNA-ribosyltransferase activity
BKK81_RS16960	COG1862	Preprotein translocase
BKK81_RS16965	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BKK81_RS16970	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BKK81_RS16975	COG2204	response regulator
BKK81_RS16980	COG4191	Histidine kinase
BKK81_RS17005	COG3038	cytochrome b561
BKK81_RS17015	COG0625	glutathione transferase activity
BKK81_RS17020	COG0482	sulfurtransferase activity
BKK81_RS17030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKK81_RS17050	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BKK81_RS17080	COG1981	membrane
BKK81_RS17085	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BKK81_RS17090	COG1466	dna polymerase III delta subunit
BKK81_RS17100	COG0495	leucyl-tRNA aminoacylation
BKK81_RS17105	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BKK81_RS17110	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BKK81_RS17115	COG0735	belongs to the Fur family
BKK81_RS17120	COG0583	DNA-binding transcription factor activity
BKK81_RS17125	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BKK81_RS17130	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BKK81_RS17135	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BKK81_RS17145	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BKK81_RS17165	COG0281	malic enzyme
BKK81_RS17165	COG0280	phosphate acetyltransferase
BKK81_RS17175	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BKK81_RS17180	COG1058	Belongs to the CinA family
BKK81_RS17180	COG1546	Belongs to the CinA family
BKK81_RS17185	COG0284	orotidine-5'-phosphate decarboxylase activity
BKK81_RS17200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKK81_RS17205	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BKK81_RS17215	COG0557	exoribonuclease II activity
BKK81_RS17220	COG1028	Short-chain dehydrogenase reductase Sdr
BKK81_RS17225	COG3161	chorismate lyase activity
BKK81_RS17235	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BKK81_RS17250	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BKK81_RS17255	COG0511	ligase activity, forming carbon-carbon bonds
BKK81_RS17260	COG0439	Biotin carboxylase
BKK81_RS17265	COG2264	protein methyltransferase activity
BKK81_RS17275	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BKK81_RS17280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKK81_RS17300	COG3181	Tripartite tricarboxylate transporter family receptor
BKK81_RS17305	COG4774	siderophore transport
BKK81_RS17310	COG3128	pkhd-type hydroxylase
BKK81_RS17325	COG0656	L-ascorbic acid biosynthetic process
BKK81_RS17340	COG2974	May be involved in recombination
BKK81_RS17395	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BKK81_RS17400	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BKK81_RS17410	COG1280	lysine exporter protein (LysE YggA)
BKK81_RS17435	COG0741	lytic transglycosylase activity
BKK81_RS17440	COG0442	prolyl-tRNA aminoacylation
BKK81_RS17445	COG0494	nUDIX hydrolase
BKK81_RS17455	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BKK81_RS17460	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BKK81_RS17465	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BKK81_RS17470	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BKK81_RS17475	COG0142	geranyltranstransferase activity
BKK81_RS17490	COG1459	type II secretion system
BKK81_RS17500	COG0237	dephospho-CoA kinase activity
BKK81_RS17505	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BKK81_RS17510	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BKK81_RS17515	COG0494	nUDIX hydrolase
BKK81_RS17525	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BKK81_RS17530	COG0653	protein targeting
BKK81_RS17540	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BKK81_RS17545	COG0678	peroxiredoxin activity
BKK81_RS17560	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BKK81_RS17565	COG1181	Belongs to the D-alanine--D-alanine ligase family
BKK81_RS17570	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BKK81_RS17575	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BKK81_RS17585	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BKK81_RS17590	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BKK81_RS17595	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BKK81_RS17600	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BKK81_RS17610	COG3116	cell division
BKK81_RS17615	COG0275	rRNA processing
BKK81_RS17620	COG2001	Belongs to the MraZ family
BKK81_RS17625	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BKK81_RS17630	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BKK81_RS17645	COG0318	PFAM AMP-dependent synthetase and ligase
BKK81_RS17650	COG1309	transcriptional regulator
BKK81_RS17655	COG0318	PFAM AMP-dependent synthetase and ligase
BKK81_RS17660	COG4770	biotin carboxylase activity
BKK81_RS17675	COG0243	molybdopterin cofactor binding
BKK81_RS17685	COG4608	Belongs to the ABC transporter superfamily
BKK81_RS17695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKK81_RS17700	COG0601	transmembrane transport
BKK81_RS17705	COG0747	negative chemotaxis
BKK81_RS17710	COG1473	amidohydrolase
BKK81_RS17750	COG1024	Enoyl-CoA hydratase
BKK81_RS17765	COG0464	growth
BKK81_RS17770	COG1404	Belongs to the peptidase S8 family
BKK81_RS17815	COG0798	PFAM Bile acid sodium symporter
BKK81_RS17830	COG0346	lactoylglutathione lyase activity
BKK81_RS17855	COG0723	plastoquinol--plastocyanin reductase activity
BKK81_RS17860	COG0431	NADPH-dependent FMN reductase
BKK81_RS17870	COG0640	Transcriptional regulator
BKK81_RS17880	COG2072	flavoprotein involved in K transport
BKK81_RS17885	COG1024	Enoyl-CoA hydratase
BKK81_RS17890	COG2050	protein possibly involved in aromatic compounds catabolism
BKK81_RS17910	COG2967	ApaG domain
BKK81_RS17915	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BKK81_RS17920	COG0546	phosphoglycolate phosphatase activity
BKK81_RS17935	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BKK81_RS17940	COG0134	indole-3-glycerol-phosphate synthase activity
BKK81_RS17950	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BKK81_RS17955	COG1254	Belongs to the acylphosphatase family
BKK81_RS17960	COG1175	transmembrane transport
BKK81_RS17965	COG1116	anion transmembrane transporter activity
BKK81_RS17970	COG1289	transmembrane transporter activity
BKK81_RS17980	COG0604	alcohol dehydrogenase
BKK81_RS17990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKK81_RS17995	COG0012	GTP binding
BKK81_RS18000	COG0582	viral genome integration into host DNA
BKK81_RS18010	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BKK81_RS18015	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BKK81_RS18040	COG0671	phosphoesterase, PA-phosphatase related
BKK81_RS18065	COG2814	Major facilitator Superfamily
BKK81_RS18080	COG0307	riboflavin synthase, alpha
BKK81_RS18130	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BKK81_RS18140	COG3181	Tripartite tricarboxylate transporter family receptor
BKK81_RS18160	COG2207	Transcriptional regulator
BKK81_RS18195	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BKK81_RS18205	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BKK81_RS18210	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BKK81_RS18220	COG2890	protein-(glutamine-N5) methyltransferase activity
BKK81_RS18225	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BKK81_RS18240	COG1012	belongs to the aldehyde dehydrogenase family
BKK81_RS18270	COG0038	chloride channel
BKK81_RS18285	COG1028	Short-chain dehydrogenase reductase Sdr
BKK81_RS18305	COG1408	metallophosphoesterase
BKK81_RS18310	COG0488	(ABC) transporter
BKK81_RS18320	COG1451	nucleotide metabolic process
BKK81_RS18330	COG3181	Tripartite tricarboxylate transporter family receptor
BKK81_RS18335	COG0583	DNA-binding transcription factor activity
BKK81_RS18365	COG0583	DNA-binding transcription factor activity
BKK81_RS18375	COG3181	Tripartite tricarboxylate transporter family receptor
BKK81_RS18395	COG2969	positive regulation of protein catabolic process
BKK81_RS18400	COG0625	glutathione transferase activity
BKK81_RS18405	COG2857	Cytochrome c1
BKK81_RS18410	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BKK81_RS18415	COG0723	plastoquinol--plastocyanin reductase activity
BKK81_RS18420	COG1970	mechanosensitive ion channel activity
BKK81_RS18425	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BKK81_RS18430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKK81_RS18435	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BKK81_RS18440	COG0805	protein transport
BKK81_RS18445	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BKK81_RS18450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BKK81_RS18460	COG0140	phosphoribosyl-ATP diphosphatase activity
BKK81_RS18465	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BKK81_RS18490	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BKK81_RS18495	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BKK81_RS18515	COG0842	Transport permease protein
BKK81_RS18570	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BKK81_RS18920	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BKK81_RS19320	COG0469	pyruvate kinase activity
BKK81_RS19370	COG2814	Major facilitator Superfamily
BKK81_RS19420	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BKK81_RS19475	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BKK81_RS19475	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BKK81_RS19480	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BKK81_RS19480	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BKK81_RS19750	COG2205	protein histidine kinase activity
BKK81_RS19925	COG2197	response regulator
BKK81_RS20495	COG2366	antibiotic biosynthetic process
BKK81_RS21060	COG4168	peptide transport system, permease
BKK81_RS21075	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BKK81_RS21285	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BKK81_RS21360	COG0768	penicillin binding
BKK81_RS21370	COG1792	Involved in formation and maintenance of cell shape
BKK81_RS21585	COG0018	arginyl-trna synthetase
BKK81_RS21665	COG0156	8-amino-7-oxononanoate synthase activity
BKK81_RS21670	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BKK81_RS22385	COG0793	Belongs to the peptidase S41A family
BKK81_RS22425	COG2226	methyltransferase
BKK81_RS22850	COG4178	(ABC) transporter
BKK81_RS22925	COG1960	acyl-CoA dehydrogenase activity
BKK81_RS22945	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKK81_RS22945	COG1024	Enoyl-CoA hydratase
BKK81_RS22980	COG5265	(ABC) transporter
BKK81_RS23005	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BKK81_RS23095	COG1490	D-aminoacyl-tRNA deacylase activity
BKK81_RS23270	COG1464	Belongs to the NlpA lipoprotein family
BKK81_RS23545	COG2274	protein secretion by the type I secretion system
BKK81_RS23650	COG0045	succinate-CoA ligase (ADP-forming) activity
BKK81_RS23730	COG4783	chaperone-mediated protein folding
BKK81_RS24020	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BKK81_RS24040	COG0583	DNA-binding transcription factor activity
BKK81_RS24515	COG0840	transmembrane signaling receptor activity
BKK81_RS24685	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BKK81_RS24720	COG1063	alcohol dehydrogenase
BKK81_RS25360	COG1674	ftsk spoiiie
BKK81_RS25405	COG0583	DNA-binding transcription factor activity
BKK81_RS25485	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BKK81_RS25550	COG2951	lytic endotransglycosylase activity
BKK81_RS25735	COG0151	Belongs to the GarS family
BKK81_RS25770	COG2010	Cytochrome c
BKK81_RS25770	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BKK81_RS26260	COG3383	formate dehydrogenase (NAD+) activity
BKK81_RS26800	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BKK81_RS26890	COG1104	cysteine desulfurase activity
BKK81_RS26910	COG0443	Heat shock 70 kDa protein
BKK81_RS26915	COG0443	Heat shock 70 kDa protein
BKK81_RS27075	COG0596	Alpha beta hydrolase
BKK81_RS27100	COG0180	Tryptophanyl-tRNA synthetase
BKK81_RS27275	COG0527	aspartate kinase activity
BKK81_RS27720	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BKK81_RS27900	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BKK81_RS28210	COG0145	ligase activity
BKK81_RS28730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKK81_RS29015	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BKK81_RS29195	COG0747	negative chemotaxis
BKK81_RS29540	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BKK81_RS29570	COG2205	protein histidine kinase activity
BKK81_RS29570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKK81_RS29580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKK81_RS29580	COG2205	protein histidine kinase activity
BKK81_RS29655	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BKK81_RS29655	COG0047	phosphoribosylformylglycinamidine synthase activity
BKK81_RS29670	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BKK81_RS29715	COG0544	peptidyl-prolyl cis-trans isomerase activity
BKK81_RS29835	COG0747	negative chemotaxis
BKK81_RS29955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKK81_RS30075	COG1012	belongs to the aldehyde dehydrogenase family
BKK81_RS30500	COG4770	biotin carboxylase activity
BKK81_RS31085	COG3188	usher protein
BKK81_RS31095	COG3121	Chaperone
BKK81_RS31330	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BKK81_RS31370	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BKK81_RS31535	COG0303	'Molybdopterin
BKK81_RS31715	COG0195	Participates in both transcription termination and antitermination
BKK81_RS31715	COG2251	uridine kinase activity
BKK81_RS31800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKK81_RS31975	COG2910	NAD(P)H-binding
BKK81_RS32260	COG4172	Belongs to the ABC transporter superfamily
BKK81_RS32375	COG0505	Belongs to the CarA family
BKK81_RS32450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKK81_RS32450	COG2205	protein histidine kinase activity
BKK81_RS32620	COG1381	Involved in DNA repair and RecF pathway recombination
BKK81_RS32645	COG0681	Belongs to the peptidase S26 family
BKK81_RS32695	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKK81_RS32860	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BKK81_RS33010	COG0070	glutamate synthase
BKK81_RS33010	COG0069	glutamate synthase activity
BKK81_RS33010	COG0067	glutamate synthase
BKK81_RS33020	COG0070	glutamate synthase
BKK81_RS33020	COG0067	glutamate synthase
BKK81_RS33020	COG0069	glutamate synthase activity
BKK81_RS33025	COG0070	glutamate synthase
BKK81_RS33025	COG0067	glutamate synthase
BKK81_RS33025	COG0069	glutamate synthase activity
BKK81_RS33040	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BKK81_RS33655	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKK81_RS33735	COG0469	pyruvate kinase activity
BKK81_RS33845	COG0404	The glycine cleavage system catalyzes the degradation of glycine