locus-tag	class	description
ALW23_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ALW23_RS00010	COG0592	DNA-directed DNA polymerase activity
ALW23_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ALW23_RS00030	COG1132	(ABC) transporter
ALW23_RS00050	COG1482	cell wall glycoprotein biosynthetic process
ALW23_RS00055	COG0187	DNA topoisomerase II activity
ALW23_RS00060	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ALW23_RS00070	COG0039	L-malate dehydrogenase activity
ALW23_RS00075	COG1609	Transcriptional regulator
ALW23_RS00080	COG1129	ABC transporter
ALW23_RS00085	COG1172	Belongs to the binding-protein-dependent transport system permease family
ALW23_RS00095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ALW23_RS00100	COG1869	D-ribose catabolic process
ALW23_RS00120	COG3775	system Galactitol-specific IIC component
ALW23_RS00125	COG3414	Phosphotransferase system galactitol-specific IIB component
ALW23_RS00130	COG1063	alcohol dehydrogenase
ALW23_RS00155	COG1349	DNA-binding transcription factor activity
ALW23_RS00165	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ALW23_RS00235	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ALW23_RS00255	COG4591	ABC-type transport system involved in lipoprotein release permease component
ALW23_RS00260	COG0577	efflux transmembrane transporter activity
ALW23_RS00260	COG1136	(ABC) transporter
ALW23_RS00265	COG2197	response regulator
ALW23_RS00275	COG0395	ABC-type sugar transport system, permease component
ALW23_RS00280	COG1175	transmembrane transport
ALW23_RS00290	COG1349	DNA-binding transcription factor activity
ALW23_RS00310	COG0546	phosphoglycolate phosphatase activity
ALW23_RS00320	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ALW23_RS00330	COG4585	Histidine kinase
ALW23_RS00340	COG1309	transcriptional regulator
ALW23_RS00345	COG2409	Drug exporters of the RND superfamily
ALW23_RS00365	COG1136	(ABC) transporter
ALW23_RS00380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ALW23_RS00385	COG1120	ATPase activity
ALW23_RS00400	COG0058	SHG alpha-glucan phosphorylase activity
ALW23_RS00415	COG5426	von Willebrand factor, type A
ALW23_RS00430	COG1175	transmembrane transport
ALW23_RS00435	COG0395	ABC-type sugar transport system, permease component
ALW23_RS00460	COG0205	6-phosphofructokinase activity
ALW23_RS00480	COG1027	Aspartate ammonia-lyase
ALW23_RS00485	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ALW23_RS00500	COG1132	(ABC) transporter
ALW23_RS00505	COG1132	(ABC) transporter
ALW23_RS00510	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
ALW23_RS00525	COG0641	radical SAM
ALW23_RS00530	COG1120	ATPase activity
ALW23_RS00545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ALW23_RS00555	COG4716	Myosin-crossreactive antigen
ALW23_RS00560	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ALW23_RS00560	COG0352	thiamine-phosphate diphosphorylase activity
ALW23_RS00560	COG0351	phosphomethylpyrimidine kinase
ALW23_RS00570	COG0352	thiamine-phosphate diphosphorylase activity
ALW23_RS00630	COG0798	PFAM Bile acid sodium symporter
ALW23_RS00635	COG0446	pyridine nucleotide-disulphide oxidoreductase
ALW23_RS00695	COG2184	nucleotidyltransferase activity
ALW23_RS00710	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ALW23_RS00740	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ALW23_RS00750	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ALW23_RS00775	COG0488	(ABC) transporter
ALW23_RS00825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ALW23_RS00855	COG0438	transferase activity, transferring glycosyl groups
ALW23_RS00890	COG3104	oligopeptide transport
ALW23_RS00900	COG1028	Short-chain dehydrogenase reductase Sdr
ALW23_RS00910	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ALW23_RS00910	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ALW23_RS00915	COG1105	Belongs to the carbohydrate kinase PfkB family
ALW23_RS00925	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ALW23_RS00935	COG0438	transferase activity, transferring glycosyl groups
ALW23_RS00945	COG0297	glycogen (starch) synthase activity
ALW23_RS00965	COG1252	NADH dehydrogenase
ALW23_RS00975	COG1643	Atp-dependent helicase
ALW23_RS00980	COG4721	ABC-type cobalt transport system, permease component
ALW23_RS00985	COG3845	ABC transporter
ALW23_RS01005	COG0167	dihydroorotate dehydrogenase activity
ALW23_RS01010	COG0674	pyruvate-flavodoxin oxidoreductase activity
ALW23_RS01010	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ALW23_RS01010	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ALW23_RS01010	COG1013	pyruvate-flavodoxin oxidoreductase activity
ALW23_RS01025	COG2186	Transcriptional regulator
ALW23_RS01030	COG1620	l-lactate permease
ALW23_RS01035	COG0247	lactate metabolic process
ALW23_RS01040	COG1139	Iron-sulfur cluster binding protein
ALW23_RS01045	COG1556	Lactate utilization protein
ALW23_RS01050	COG1122	ATPase activity
ALW23_RS01065	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ALW23_RS01070	COG4988	ABC transporter
ALW23_RS01075	COG1294	oxidase, subunit
ALW23_RS01080	COG1271	oxidase subunit
ALW23_RS01110	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ALW23_RS01125	COG2815	serine threonine protein kinase
ALW23_RS01125	COG0515	serine threonine protein kinase
ALW23_RS01130	COG0768	penicillin binding
ALW23_RS01250	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ALW23_RS01255	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ALW23_RS01265	COG0577	efflux transmembrane transporter activity
ALW23_RS01265	COG1136	(ABC) transporter
ALW23_RS01280	COG0561	phosphatase activity
ALW23_RS01285	COG0561	phosphatase activity
ALW23_RS01290	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ALW23_RS01295	COG3842	ATPase activity
ALW23_RS01310	COG3681	Belongs to the UPF0597 family
ALW23_RS01315	COG0814	amino acid
ALW23_RS01320	COG0673	inositol 2-dehydrogenase activity
ALW23_RS01350	COG0494	nUDIX hydrolase
ALW23_RS01360	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ALW23_RS01415	COG1111	helicase
ALW23_RS01415	COG1205	dead DEAH box helicase
ALW23_RS01420	COG2890	protein-(glutamine-N5) methyltransferase activity
ALW23_RS01430	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ALW23_RS01430	COG1754	DNA topoisomerase type I activity
ALW23_RS01440	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ALW23_RS01445	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ALW23_RS01455	COG1774	PSP1 C-terminal conserved region
ALW23_RS01480	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ALW23_RS01495	COG3458	cephalosporin-C deacetylase activity
ALW23_RS01505	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ALW23_RS01515	COG0037	tRNA processing
ALW23_RS01530	COG0302	gtp cyclohydrolase
ALW23_RS01570	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ALW23_RS01575	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ALW23_RS01595	COG0649	NAD binding
ALW23_RS01625	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ALW23_RS01630	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ALW23_RS01635	COG1984	allophanate hydrolase subunit 2
ALW23_RS01645	COG1090	epimerase
ALW23_RS01650	COG0705	Rhomboid family
ALW23_RS01660	COG2197	response regulator
ALW23_RS01665	COG4585	Histidine kinase
ALW23_RS01675	COG3711	transcriptional antiterminator
ALW23_RS01680	COG2190	(PTS) system
ALW23_RS01680	COG1263	PTS System
ALW23_RS01680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ALW23_RS01685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ALW23_RS01685	COG1263	PTS System
ALW23_RS01685	COG2190	(PTS) system
ALW23_RS01700	COG1194	a g-specific adenine glycosylase
ALW23_RS01705	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ALW23_RS01710	COG0113	porphobilinogen synthase activity
ALW23_RS01720	COG0181	hydroxymethylbilane synthase activity
ALW23_RS01730	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ALW23_RS01735	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ALW23_RS01740	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ALW23_RS01740	COG3253	May function as heme-dependent peroxidase
ALW23_RS01755	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ALW23_RS01760	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ALW23_RS01775	COG1082	Xylose isomerase domain protein TIM barrel
ALW23_RS01780	COG0506	proline dehydrogenase activity
ALW23_RS01795	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ALW23_RS01815	COG0406	alpha-ribazole phosphatase activity
ALW23_RS01820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ALW23_RS01825	COG0785	Cytochrome C biogenesis protein
ALW23_RS01830	COG1333	cytochrome c biogenesis protein
ALW23_RS01835	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ALW23_RS01845	COG4221	oxidoreductase activity
ALW23_RS01870	COG1120	ATPase activity
ALW23_RS01875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ALW23_RS01885	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ALW23_RS01905	COG0494	nUDIX hydrolase
ALW23_RS01905	COG0406	alpha-ribazole phosphatase activity
ALW23_RS01910	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ALW23_RS01915	COG0745	RESPONSE REGULATOR receiver
ALW23_RS01925	COG1490	D-aminoacyl-tRNA deacylase activity
ALW23_RS01930	COG3485	protocatechuate 3,4-dioxygenase
ALW23_RS01940	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ALW23_RS01950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ALW23_RS01955	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ALW23_RS01960	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ALW23_RS01965	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ALW23_RS01980	COG1329	Transcriptional regulator
ALW23_RS02015	COG0588	phosphoglycerate mutase activity
ALW23_RS02030	COG0252	asparaginase activity
ALW23_RS02035	COG1113	amino acid transport
ALW23_RS02040	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ALW23_RS02045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ALW23_RS02050	COG0800	Aldolase
ALW23_RS02060	COG5492	domain, Protein
ALW23_RS02075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ALW23_RS02080	COG0215	cysteine-tRNA ligase activity
ALW23_RS02135	COG3842	ATPase activity
ALW23_RS02145	COG1760	l-serine dehydratase
ALW23_RS02150	COG0673	inositol 2-dehydrogenase activity
ALW23_RS02155	COG2182	Extracellular solute-binding protein
ALW23_RS02160	COG1175	transmembrane transport
ALW23_RS02165	COG0395	ABC-type sugar transport system, permease component
ALW23_RS02170	COG1063	alcohol dehydrogenase
ALW23_RS02185	COG1174	glycine betaine transport
ALW23_RS02210	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ALW23_RS02215	COG2130	NADP-dependent
ALW23_RS02220	COG1131	(ABC) transporter
ALW23_RS02230	COG4585	Histidine kinase
ALW23_RS02235	COG2197	response regulator
ALW23_RS02240	COG0406	alpha-ribazole phosphatase activity
ALW23_RS02245	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ALW23_RS02250	COG1492	cobalamin metabolic process
ALW23_RS02270	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ALW23_RS02270	COG1648	precorrin-2 dehydrogenase activity
ALW23_RS02280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ALW23_RS02285	COG1120	ATPase activity
ALW23_RS02305	COG0310	cobalt ion transport
ALW23_RS02340	COG1797	cobyrinic acid a,c-diamide synthase activity
ALW23_RS02350	COG2099	Precorrin-6x reductase
ALW23_RS02355	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ALW23_RS02385	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ALW23_RS02385	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ALW23_RS02385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ALW23_RS02400	COG1854	S-ribosylhomocysteine lyase activity
ALW23_RS02420	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ALW23_RS02430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ALW23_RS02440	COG3718	enzyme involved in inositol metabolism
ALW23_RS02445	COG3962	Belongs to the TPP enzyme family
ALW23_RS02455	COG1012	belongs to the aldehyde dehydrogenase family
ALW23_RS02460	COG1609	Transcriptional regulator
ALW23_RS02470	COG1082	Xylose isomerase domain protein TIM barrel
ALW23_RS02475	COG1082	Xylose isomerase domain protein TIM barrel
ALW23_RS02480	COG0673	inositol 2-dehydrogenase activity
ALW23_RS02485	COG2814	Major facilitator Superfamily
ALW23_RS02500	COG1082	Xylose isomerase domain protein TIM barrel
ALW23_RS02505	COG0673	inositol 2-dehydrogenase activity
ALW23_RS02515	COG3142	Participates in the control of copper homeostasis
ALW23_RS02525	COG1061	Type III restriction enzyme res subunit
ALW23_RS02540	COG0363	glucosamine-6-phosphate deaminase activity
ALW23_RS02545	COG1278	Cold shock
ALW23_RS02560	COG2252	PERMEase
ALW23_RS02575	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ALW23_RS02600	COG2814	Major facilitator Superfamily
ALW23_RS02620	COG1970	mechanosensitive ion channel activity
ALW23_RS02635	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ALW23_RS02640	COG0303	'Molybdopterin
ALW23_RS02665	COG0315	cyclic pyranopterin monophosphate synthase activity
ALW23_RS02685	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ALW23_RS02720	COG1140	nitrate reductase beta subunit
ALW23_RS02740	COG0521	Mo-molybdopterin cofactor biosynthetic process
ALW23_RS02740	COG0315	cyclic pyranopterin monophosphate synthase activity
ALW23_RS02755	COG0437	4 iron, 4 sulfur cluster binding
ALW23_RS02760	COG0243	molybdopterin cofactor binding
ALW23_RS02770	COG2022	thiamine diphosphate biosynthetic process
ALW23_RS02780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ALW23_RS02780	COG2022	thiamine diphosphate biosynthetic process
ALW23_RS02785	COG0598	Magnesium transport protein CorA
ALW23_RS02790	COG2233	PERMEase
ALW23_RS02805	COG0084	hydrolase, TatD family'
ALW23_RS02810	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ALW23_RS02815	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ALW23_RS02820	COG1846	Transcriptional regulator
ALW23_RS02835	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ALW23_RS02840	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ALW23_RS02860	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ALW23_RS02865	COG0193	aminoacyl-tRNA hydrolase activity
ALW23_RS02915	COG0148	phosphopyruvate hydratase activity
ALW23_RS02980	COG1297	OPT oligopeptide transporter protein
ALW23_RS02985	COG0667	Aldo Keto reductase
ALW23_RS02990	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ALW23_RS02995	COG0733	neurotransmitter:sodium symporter activity
ALW23_RS03000	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ALW23_RS03015	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ALW23_RS03030	COG1331	Highly conserved protein containing a thioredoxin domain
ALW23_RS03035	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ALW23_RS03045	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ALW23_RS03055	COG1722	exodeoxyribonuclease VII activity
ALW23_RS03060	COG1570	exodeoxyribonuclease VII activity
ALW23_RS03070	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ALW23_RS03075	COG1322	Protein conserved in bacteria
ALW23_RS03080	COG1362	aminopeptidase activity
ALW23_RS03085	COG0012	GTP binding
ALW23_RS03105	COG1846	Transcriptional regulator
ALW23_RS03110	COG1764	response to oxidative stress
ALW23_RS03125	COG2235	arginine
ALW23_RS03130	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ALW23_RS03155	COG0667	Aldo Keto reductase
ALW23_RS03160	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ALW23_RS03165	COG0833	amino acid
ALW23_RS03170	COG0366	Alpha amylase catalytic
ALW23_RS03170	COG3103	Sh3 type 3 domain protein
ALW23_RS03205	COG1404	Belongs to the peptidase S8 family
ALW23_RS03210	COG2501	S4 domain
ALW23_RS03215	COG1126	abc transporter atp-binding protein
ALW23_RS03245	COG1176	ABC-type spermidine putrescine transport system, permease component I
ALW23_RS03250	COG0395	ABC-type sugar transport system, permease component
ALW23_RS03260	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
ALW23_RS03280	COG1136	(ABC) transporter
ALW23_RS03290	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ALW23_RS03300	COG0803	Belongs to the bacterial solute-binding protein 9 family
ALW23_RS03315	COG1012	belongs to the aldehyde dehydrogenase family
ALW23_RS03320	COG1063	alcohol dehydrogenase
ALW23_RS03325	COG2376	Dihydroxyacetone kinase
ALW23_RS03330	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ALW23_RS03340	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ALW23_RS03345	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ALW23_RS03350	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ALW23_RS03365	COG2171	N-acyltransferase activity
ALW23_RS03370	COG1834	amidinotransferase
ALW23_RS03380	COG0477	Major facilitator Superfamily
ALW23_RS03405	COG0297	glycogen (starch) synthase activity
ALW23_RS03410	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ALW23_RS03420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ALW23_RS03425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ALW23_RS03460	COG0006	proline dipeptidase activity
ALW23_RS03490	COG4139	cobalamin transport
ALW23_RS03495	COG1120	ATPase activity
ALW23_RS03530	COG0174	glutamine synthetase
ALW23_RS03540	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ALW23_RS03545	COG2966	Psort location CytoplasmicMembrane, score
ALW23_RS03565	COG0174	glutamine synthetase
ALW23_RS03575	COG0438	transferase activity, transferring glycosyl groups
ALW23_RS03585	COG1263	PTS System
ALW23_RS03590	COG2188	Transcriptional regulator
ALW23_RS03595	COG1263	PTS System
ALW23_RS03595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ALW23_RS03600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ALW23_RS03610	COG3477	response to acidic pH
ALW23_RS03615	COG5650	phosphatidylinositol metabolic process
ALW23_RS03620	COG0488	(ABC) transporter
ALW23_RS03655	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ALW23_RS03670	COG0321	lipoyl(octanoyl) transferase activity
ALW23_RS03675	COG0508	dehydrogenase complex catalyzes the overall conversion of
ALW23_RS03680	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ALW23_RS03715	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ALW23_RS03720	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ALW23_RS03735	COG1136	(ABC) transporter
ALW23_RS03760	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ALW23_RS03765	COG0723	plastoquinol--plastocyanin reductase activity
ALW23_RS03770	COG2010	Cytochrome c
ALW23_RS03775	COG1845	cytochrome c oxidase, subunit III
ALW23_RS03785	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)