locus-tag	class	description
CYFUS_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CYFUS_RS00020	COG4796	Type ii and iii secretion system protein
CYFUS_RS00030	COG2226	methyltransferase
CYFUS_RS00085	COG2814	Major facilitator Superfamily
CYFUS_RS00160	COG1404	Belongs to the peptidase S8 family
CYFUS_RS00170	COG2382	esterase
CYFUS_RS00175	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CYFUS_RS00185	COG0189	ligase activity
CYFUS_RS00235	COG2204	response regulator
CYFUS_RS00240	COG0515	serine threonine protein kinase
CYFUS_RS00245	COG4251	negative regulation of phosphorylation
CYFUS_RS00250	COG1879	ABC-type sugar transport system periplasmic component
CYFUS_RS00260	COG0515	serine threonine protein kinase
CYFUS_RS00270	COG1562	ergosterol biosynthetic process
CYFUS_RS00280	COG0515	serine threonine protein kinase
CYFUS_RS00300	COG3214	Protein conserved in bacteria
CYFUS_RS00320	COG2267	carboxylic ester hydrolase activity
CYFUS_RS00335	COG0515	serine threonine protein kinase
CYFUS_RS00340	COG2124	cytochrome p450
CYFUS_RS00355	COG1063	alcohol dehydrogenase
CYFUS_RS00365	COG3387	PFAM Glycoside hydrolase 15-related
CYFUS_RS00375	COG3220	belongs to the UPF0276 family
CYFUS_RS00440	COG3550	peptidyl-serine autophosphorylation
CYFUS_RS00445	COG2267	carboxylic ester hydrolase activity
CYFUS_RS00465	COG2131	deaminase
CYFUS_RS00485	COG1690	Belongs to the RtcB family
CYFUS_RS00495	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS00545	COG0515	serine threonine protein kinase
CYFUS_RS00545	COG2815	serine threonine protein kinase
CYFUS_RS00550	COG0402	S-adenosylhomocysteine deaminase activity
CYFUS_RS00555	COG2755	lipolytic protein G-D-S-L family
CYFUS_RS00555	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CYFUS_RS00575	COG1024	Enoyl-CoA hydratase
CYFUS_RS00625	COG1045	serine acetyltransferase
CYFUS_RS00670	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CYFUS_RS00680	COG0318	PFAM AMP-dependent synthetase and ligase
CYFUS_RS00685	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CYFUS_RS00700	COG4191	Histidine kinase
CYFUS_RS00700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CYFUS_RS00705	COG0438	transferase activity, transferring glycosyl groups
CYFUS_RS00730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CYFUS_RS00800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CYFUS_RS00810	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CYFUS_RS00820	COG2124	cytochrome p450
CYFUS_RS00855	COG3604	Transcriptional regulator
CYFUS_RS00870	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CYFUS_RS00880	COG2144	transferase activity, transferring acyl groups
CYFUS_RS00890	COG2072	flavoprotein involved in K transport
CYFUS_RS00930	COG0515	serine threonine protein kinase
CYFUS_RS00930	COG2815	serine threonine protein kinase
CYFUS_RS00940	COG0582	viral genome integration into host DNA
CYFUS_RS00945	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CYFUS_RS00950	COG0318	PFAM AMP-dependent synthetase and ligase
CYFUS_RS00970	COG0110	maltose O-acetyltransferase activity
CYFUS_RS00980	COG0564	pseudouridine synthase activity
CYFUS_RS00985	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CYFUS_RS01010	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CYFUS_RS01025	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CYFUS_RS01050	COG4221	oxidoreductase activity
CYFUS_RS01065	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CYFUS_RS01120	COG0546	phosphoglycolate phosphatase activity
CYFUS_RS01150	COG2204	response regulator
CYFUS_RS01170	COG3158	transport of potassium into the cell
CYFUS_RS01185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CYFUS_RS01195	COG1741	Belongs to the pirin family
CYFUS_RS01220	COG0328	RNA-DNA hybrid ribonuclease activity
CYFUS_RS01250	COG0515	serine threonine protein kinase
CYFUS_RS01260	COG5464	transposase or invertase
CYFUS_RS01290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CYFUS_RS01330	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CYFUS_RS01340	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CYFUS_RS01345	COG2205	protein histidine kinase activity
CYFUS_RS01350	COG5002	protein histidine kinase activity
CYFUS_RS01395	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CYFUS_RS01430	COG1819	glycosyl
CYFUS_RS01470	COG2814	Major facilitator Superfamily
CYFUS_RS01480	COG4257	antibiotic catabolic process
CYFUS_RS01490	COG2304	oxidoreductase activity
CYFUS_RS01500	COG5002	protein histidine kinase activity
CYFUS_RS01505	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CYFUS_RS01515	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CYFUS_RS01530	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS01540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CYFUS_RS01545	COG0318	PFAM AMP-dependent synthetase and ligase
CYFUS_RS01590	COG4953	penicillin-binding protein 1C
CYFUS_RS01595	COG2124	cytochrome p450
CYFUS_RS01610	COG0592	DNA-directed DNA polymerase activity
CYFUS_RS01620	COG2205	protein histidine kinase activity
CYFUS_RS01635	COG3186	Phenylalanine-4-hydroxylase
CYFUS_RS01700	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CYFUS_RS01715	COG1595	DNA-templated transcription, initiation
CYFUS_RS01745	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CYFUS_RS01745	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CYFUS_RS01790	COG2366	antibiotic biosynthetic process
CYFUS_RS01845	COG1278	Cold shock
CYFUS_RS01865	COG2204	response regulator
CYFUS_RS01905	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CYFUS_RS01915	COG3537	Alpha-1,2-mannosidase
CYFUS_RS01920	COG3142	Participates in the control of copper homeostasis
CYFUS_RS01960	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS01975	COG0515	serine threonine protein kinase
CYFUS_RS01975	COG2815	serine threonine protein kinase
CYFUS_RS02005	COG0515	serine threonine protein kinase
CYFUS_RS02005	COG2815	serine threonine protein kinase
CYFUS_RS02020	COG0656	L-ascorbic acid biosynthetic process
CYFUS_RS02070	COG4774	siderophore transport
CYFUS_RS02085	COG3128	pkhd-type hydroxylase
CYFUS_RS02090	COG3852	Histidine kinase
CYFUS_RS02105	COG1252	NADH dehydrogenase
CYFUS_RS02130	COG0840	transmembrane signaling receptor activity
CYFUS_RS02140	COG2201	protein-glutamate methylesterase activity
CYFUS_RS02155	COG0653	protein targeting
CYFUS_RS02165	COG2197	response regulator
CYFUS_RS02195	COG1056	cytidyltransferase-related domain
CYFUS_RS02195	COG1051	belongs to the nudix hydrolase family
CYFUS_RS02225	COG2205	protein histidine kinase activity
CYFUS_RS02225	COG0784	Response regulator, receiver
CYFUS_RS02240	COG3118	belongs to the thioredoxin family
CYFUS_RS02245	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CYFUS_RS02270	COG4191	Histidine kinase
CYFUS_RS02275	COG1024	Enoyl-CoA hydratase
CYFUS_RS02280	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CYFUS_RS02285	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CYFUS_RS02295	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CYFUS_RS02345	COG3209	COG3209 Rhs family protein
CYFUS_RS02350	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS02370	COG0477	Major facilitator Superfamily
CYFUS_RS02375	COG4191	Histidine kinase
CYFUS_RS02400	COG0545	Peptidyl-prolyl cis-trans isomerase
CYFUS_RS02465	COG0583	DNA-binding transcription factor activity
CYFUS_RS02515	COG4991	sh3 domain protein
CYFUS_RS02515	COG3064	Membrane
CYFUS_RS02515	COG0515	serine threonine protein kinase
CYFUS_RS02575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CYFUS_RS02580	COG0667	Aldo Keto reductase
CYFUS_RS02625	COG2423	ornithine cyclodeaminase activity
CYFUS_RS02715	COG2226	methyltransferase
CYFUS_RS02725	COG0653	protein targeting
CYFUS_RS02775	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CYFUS_RS02780	COG0443	Heat shock 70 kDa protein
CYFUS_RS02800	COG2201	protein-glutamate methylesterase activity
CYFUS_RS02810	COG0643	Histidine kinase
CYFUS_RS02810	COG2198	Histidine kinase
CYFUS_RS02820	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS02830	COG2205	protein histidine kinase activity
CYFUS_RS02835	COG0784	Response regulator, receiver
CYFUS_RS02840	COG4251	negative regulation of phosphorylation
CYFUS_RS02865	COG0300	oxidoreductase activity
CYFUS_RS02925	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CYFUS_RS02925	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CYFUS_RS02925	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CYFUS_RS02930	COG1105	Belongs to the carbohydrate kinase PfkB family
CYFUS_RS02935	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CYFUS_RS02935	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CYFUS_RS02940	COG1609	Transcriptional regulator
CYFUS_RS02945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CYFUS_RS02950	COG0235	Class ii aldolase
CYFUS_RS02955	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CYFUS_RS02960	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CYFUS_RS02975	COG0574	Belongs to the PEP-utilizing enzyme family
CYFUS_RS02975	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CYFUS_RS03045	COG0375	protein maturation
CYFUS_RS03050	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CYFUS_RS03070	COG0517	IMP dehydrogenase activity
CYFUS_RS03070	COG0516	GMP reductase activity
CYFUS_RS03085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CYFUS_RS03095	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CYFUS_RS03105	COG5002	protein histidine kinase activity
CYFUS_RS03110	COG0427	acetyl-CoA hydrolase
CYFUS_RS03115	COG3158	transport of potassium into the cell
CYFUS_RS03155	COG0189	ligase activity
CYFUS_RS03190	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CYFUS_RS03220	COG1858	cytochrome C peroxidase
CYFUS_RS03230	COG5002	protein histidine kinase activity
CYFUS_RS03270	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CYFUS_RS03335	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CYFUS_RS03340	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CYFUS_RS03355	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CYFUS_RS03375	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CYFUS_RS03380	COG0515	serine threonine protein kinase
CYFUS_RS03385	COG1366	Belongs to the anti-sigma-factor antagonist family
CYFUS_RS03390	COG1366	Belongs to the anti-sigma-factor antagonist family
CYFUS_RS03395	COG2172	sigma factor antagonist activity
CYFUS_RS03405	COG2205	protein histidine kinase activity
CYFUS_RS03410	COG5002	protein histidine kinase activity
CYFUS_RS03430	COG0631	protein serine/threonine phosphatase activity
CYFUS_RS03445	COG1515	deoxyribonuclease V activity
CYFUS_RS03465	COG2010	Cytochrome c
CYFUS_RS03520	COG3227	Zinc metalloprotease (Elastase)
CYFUS_RS03545	COG0071	Belongs to the small heat shock protein (HSP20) family
CYFUS_RS03565	COG3852	Histidine kinase
CYFUS_RS03570	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CYFUS_RS03595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CYFUS_RS03625	COG3852	Histidine kinase
CYFUS_RS03640	COG0356	it plays a direct role in the translocation of protons across the membrane
CYFUS_RS03645	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CYFUS_RS03650	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CYFUS_RS03655	COG0012	GTP binding
CYFUS_RS03660	COG0372	Belongs to the citrate synthase family
CYFUS_RS03700	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS03705	COG0784	Response regulator, receiver
CYFUS_RS03705	COG2205	protein histidine kinase activity
CYFUS_RS03710	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CYFUS_RS03735	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CYFUS_RS03790	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CYFUS_RS03825	COG3011	Protein conserved in bacteria
CYFUS_RS03830	COG2205	protein histidine kinase activity
CYFUS_RS03830	COG5002	protein histidine kinase activity
CYFUS_RS03830	COG0784	Response regulator, receiver
CYFUS_RS03835	COG5002	protein histidine kinase activity
CYFUS_RS03845	COG3844	kynureninase activity
CYFUS_RS03855	COG0166	Belongs to the GPI family
CYFUS_RS03860	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS03870	COG0346	lactoylglutathione lyase activity
CYFUS_RS03880	COG2843	Capsule synthesis protein
CYFUS_RS03905	COG0765	amino acid transport
CYFUS_RS03925	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CYFUS_RS03930	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CYFUS_RS03935	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CYFUS_RS03960	COG4191	Histidine kinase
CYFUS_RS03965	COG2070	2-Nitropropane dioxygenase
CYFUS_RS03975	COG0583	DNA-binding transcription factor activity
CYFUS_RS03995	COG0602	queuosine metabolic process
CYFUS_RS04000	COG2816	NAD+ diphosphatase activity
CYFUS_RS04005	COG2124	cytochrome p450
CYFUS_RS04025	COG4771	TonB-dependent receptor
CYFUS_RS04045	COG2815	serine threonine protein kinase
CYFUS_RS04045	COG0515	serine threonine protein kinase
CYFUS_RS04110	COG0436	Aminotransferase
CYFUS_RS04120	COG0551	DNA topoisomerase type I activity
CYFUS_RS04120	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CYFUS_RS04135	COG1388	LysM domain
CYFUS_RS04135	COG3942	CHAP domain
CYFUS_RS04140	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CYFUS_RS04145	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CYFUS_RS04150	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CYFUS_RS04155	COG5002	protein histidine kinase activity
CYFUS_RS04160	COG0515	serine threonine protein kinase
CYFUS_RS04165	COG0842	Transport permease protein
CYFUS_RS04170	COG1131	(ABC) transporter
CYFUS_RS04175	COG0488	(ABC) transporter
CYFUS_RS04200	COG2815	serine threonine protein kinase
CYFUS_RS04200	COG0515	serine threonine protein kinase
CYFUS_RS04225	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CYFUS_RS04250	COG1525	nuclease
CYFUS_RS04265	COG0668	transmembrane transport
CYFUS_RS04270	COG0517	IMP dehydrogenase activity
CYFUS_RS04270	COG1125	glycine betaine transport
CYFUS_RS04275	COG1174	glycine betaine transport
CYFUS_RS04305	COG0109	protoheme IX farnesyltransferase activity
CYFUS_RS04305	COG1612	heme a metabolic process
CYFUS_RS04335	COG0671	phosphoesterase, PA-phosphatase related
CYFUS_RS04340	COG0110	maltose O-acetyltransferase activity
CYFUS_RS04345	COG4191	Histidine kinase
CYFUS_RS04385	COG3852	Histidine kinase
CYFUS_RS04415	COG1192	Involved in chromosome partitioning
CYFUS_RS04510	COG5002	protein histidine kinase activity
CYFUS_RS04520	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CYFUS_RS04555	COG2124	cytochrome p450
CYFUS_RS04605	COG0596	Alpha beta hydrolase
CYFUS_RS04610	COG4991	sh3 domain protein
CYFUS_RS04610	COG3064	Membrane
CYFUS_RS04610	COG0515	serine threonine protein kinase
CYFUS_RS04635	COG1234	tRNA 3'-trailer cleavage
CYFUS_RS04645	COG1309	transcriptional regulator
CYFUS_RS04670	COG1278	Cold shock
CYFUS_RS04685	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CYFUS_RS04695	COG2031	fatty acid transporter
CYFUS_RS04710	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CYFUS_RS04730	COG3483	tryptophan 2,3-dioxygenase activity
CYFUS_RS04740	COG3437	response regulator, receiver
CYFUS_RS04740	COG3850	Histidine kinase
CYFUS_RS04740	COG4999	Histidine kinase
CYFUS_RS04740	COG2205	protein histidine kinase activity
CYFUS_RS04760	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CYFUS_RS04765	COG1192	Involved in chromosome partitioning
CYFUS_RS04795	COG1132	(ABC) transporter
CYFUS_RS04805	COG0484	heat shock protein binding
CYFUS_RS04810	COG0515	serine threonine protein kinase
CYFUS_RS04865	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CYFUS_RS04870	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CYFUS_RS04875	COG0714	Associated with various cellular activities
CYFUS_RS04880	COG3831	ATPase activity
CYFUS_RS04895	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CYFUS_RS04915	COG3339	Conserved Protein
CYFUS_RS04930	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CYFUS_RS04935	COG0583	DNA-binding transcription factor activity
CYFUS_RS05035	COG0596	Alpha beta hydrolase
CYFUS_RS05050	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CYFUS_RS05070	COG2259	Doxx family
CYFUS_RS05150	COG0596	Alpha beta hydrolase
CYFUS_RS05175	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CYFUS_RS05190	COG1335	isochorismatase
CYFUS_RS05225	COG3852	Histidine kinase
CYFUS_RS05255	COG4221	oxidoreductase activity
CYFUS_RS05265	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CYFUS_RS05270	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CYFUS_RS05275	COG2188	Transcriptional regulator
CYFUS_RS05280	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CYFUS_RS05285	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CYFUS_RS05285	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CYFUS_RS05290	COG1263	PTS System
CYFUS_RS05290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CYFUS_RS05290	COG2190	(PTS) system
CYFUS_RS05305	COG1595	DNA-templated transcription, initiation
CYFUS_RS05320	COG4733	cellulase activity
CYFUS_RS05320	COG5297	Belongs to the glycosyl hydrolase family 6
CYFUS_RS05390	COG0018	arginyl-trna synthetase
CYFUS_RS05400	COG1960	acyl-CoA dehydrogenase activity
CYFUS_RS05415	COG4772	TonB-dependent receptor
CYFUS_RS05420	COG4251	negative regulation of phosphorylation
CYFUS_RS05425	COG0784	Response regulator, receiver
CYFUS_RS05430	COG2205	protein histidine kinase activity
CYFUS_RS05490	COG0544	peptidyl-prolyl cis-trans isomerase activity
CYFUS_RS05500	COG2234	aminopeptidase activity
CYFUS_RS05510	COG0077	Prephenate dehydratase
CYFUS_RS05510	COG1605	Chorismate mutase
CYFUS_RS05520	COG0826	peptidase U32
CYFUS_RS05545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CYFUS_RS05550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CYFUS_RS05610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CYFUS_RS05615	COG1522	sequence-specific DNA binding
CYFUS_RS05635	COG0596	Alpha beta hydrolase
CYFUS_RS05650	COG0242	peptide deformylase activity
CYFUS_RS05660	COG0443	Heat shock 70 kDa protein
CYFUS_RS05710	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CYFUS_RS05740	COG0714	Associated with various cellular activities
CYFUS_RS05755	COG1335	isochorismatase
CYFUS_RS05775	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS05780	COG0642	Histidine kinase
CYFUS_RS05800	COG2111	Na H antiporter
CYFUS_RS05800	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CYFUS_RS05805	COG1006	Multisubunit Na H antiporter MnhC subunit
CYFUS_RS05810	COG0651	ATP synthesis coupled electron transport
CYFUS_RS05815	COG1863	multisubunit Na H antiporter MnhE subunit
CYFUS_RS05820	COG2212	antiporter activity
CYFUS_RS05875	COG1011	Hydrolase
CYFUS_RS05920	COG1408	metallophosphoesterase
CYFUS_RS05925	COG1090	epimerase
CYFUS_RS05945	COG1562	ergosterol biosynthetic process
CYFUS_RS05950	COG1233	COG1233 Phytoene dehydrogenase and related
CYFUS_RS05985	COG1228	amidohydrolase
CYFUS_RS06030	COG3361	conserved protein (COG2071)
CYFUS_RS06070	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CYFUS_RS06085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CYFUS_RS06145	COG0789	Transcriptional regulator
CYFUS_RS06150	COG1505	serine-type exopeptidase activity
CYFUS_RS06170	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS06175	COG2205	protein histidine kinase activity
CYFUS_RS06185	COG1999	signal sequence binding
CYFUS_RS06205	COG2030	dehydratase
CYFUS_RS06210	COG0667	Aldo Keto reductase
CYFUS_RS06235	COG1819	glycosyl
CYFUS_RS06255	COG2274	protein secretion by the type I secretion system
CYFUS_RS06295	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CYFUS_RS06310	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CYFUS_RS06315	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CYFUS_RS06320	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CYFUS_RS06330	COG2272	Belongs to the type-B carboxylesterase lipase family
CYFUS_RS06355	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS06390	COG0420	3'-5' exonuclease activity
CYFUS_RS06410	COG4191	Histidine kinase
CYFUS_RS06430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CYFUS_RS06435	COG2304	oxidoreductase activity
CYFUS_RS06440	COG0534	Mate efflux family protein
CYFUS_RS06445	COG3733	amine oxidase
CYFUS_RS06455	COG0784	Response regulator, receiver
CYFUS_RS06460	COG4251	negative regulation of phosphorylation
CYFUS_RS06470	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
CYFUS_RS06495	COG0010	Belongs to the arginase family
CYFUS_RS06510	COG0456	acetyltransferase
CYFUS_RS06510	COG1214	PFAM Peptidase M22, glycoprotease
CYFUS_RS06530	COG1201	RNA secondary structure unwinding
CYFUS_RS06535	COG2124	cytochrome p450
CYFUS_RS06540	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS06550	COG5006	permease, DMT superfamily
CYFUS_RS06555	COG2133	pyrroloquinoline quinone binding
CYFUS_RS06585	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CYFUS_RS06605	COG0778	Nitroreductase
CYFUS_RS06615	COG4968	Prepilin-type N-terminal cleavage methylation domain
CYFUS_RS06700	COG3395	kinase activity
CYFUS_RS06720	COG0395	ABC-type sugar transport system, permease component
CYFUS_RS06730	COG3842	ATPase activity
CYFUS_RS06735	COG3842	ATPase activity
CYFUS_RS06740	COG1404	Belongs to the peptidase S8 family
CYFUS_RS06750	COG4251	negative regulation of phosphorylation
CYFUS_RS06755	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS06760	COG0784	Response regulator, receiver
CYFUS_RS06760	COG2205	protein histidine kinase activity
CYFUS_RS06765	COG2322	membrane
CYFUS_RS06815	COG1360	Flagellar Motor Protein
CYFUS_RS06825	COG4335	DNA alkylation repair
CYFUS_RS06835	COG3226	Transcriptional regulator
CYFUS_RS06855	COG5002	protein histidine kinase activity
CYFUS_RS06915	COG2226	methyltransferase
CYFUS_RS06940	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CYFUS_RS06975	COG2311	Membrane
CYFUS_RS06995	COG3724	N-succinylarginine dihydrolase activity
CYFUS_RS07000	COG1560	Kdo2-lipid A biosynthetic process
CYFUS_RS07020	COG0583	DNA-binding transcription factor activity
CYFUS_RS07030	COG0702	epimerase
CYFUS_RS07035	COG2353	YceI-like domain
CYFUS_RS07040	COG1741	Belongs to the pirin family
CYFUS_RS07045	COG0367	asparagine synthase
CYFUS_RS07055	COG1960	acyl-CoA dehydrogenase activity
CYFUS_RS07085	COG1137	ATPase activity
CYFUS_RS07100	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS07105	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CYFUS_RS07120	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CYFUS_RS07125	COG1472	Belongs to the glycosyl hydrolase 3 family
CYFUS_RS07130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CYFUS_RS07140	COG1490	D-aminoacyl-tRNA deacylase activity
CYFUS_RS07145	COG2153	protein acetylation
CYFUS_RS07155	COG0601	transmembrane transport
CYFUS_RS07170	COG2027	D-alanyl-D-alanine carboxypeptidase
CYFUS_RS07175	COG0629	single-stranded DNA binding
CYFUS_RS07180	COG2009	succinate dehydrogenase
CYFUS_RS07185	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CYFUS_RS07190	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CYFUS_RS07200	COG4191	Histidine kinase
CYFUS_RS07205	COG2204	response regulator
CYFUS_RS07210	COG1007	ATP synthesis coupled electron transport
CYFUS_RS07220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CYFUS_RS07225	COG0713	ATP synthesis coupled electron transport
CYFUS_RS07230	COG0839	Belongs to the complex I subunit 6 family
CYFUS_RS07250	COG2815	serine threonine protein kinase
CYFUS_RS07250	COG0515	serine threonine protein kinase
CYFUS_RS07255	COG3830	Belongs to the UPF0237 family
CYFUS_RS07255	COG0560	Phosphoserine phosphatase
CYFUS_RS07275	COG0071	Belongs to the small heat shock protein (HSP20) family
CYFUS_RS07285	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CYFUS_RS07290	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CYFUS_RS07295	COG0504	CTP synthase activity
CYFUS_RS07305	COG1132	(ABC) transporter
CYFUS_RS07310	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CYFUS_RS07320	COG0564	pseudouridine synthase activity
CYFUS_RS07325	COG5002	protein histidine kinase activity
CYFUS_RS07330	COG2204	response regulator
CYFUS_RS07335	COG2205	protein histidine kinase activity
CYFUS_RS07340	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CYFUS_RS07355	COG0484	heat shock protein binding
CYFUS_RS07375	COG0511	ligase activity, forming carbon-carbon bonds
CYFUS_RS07375	COG5016	pyruvate
CYFUS_RS07380	COG0439	Biotin carboxylase
CYFUS_RS07390	COG0778	Nitroreductase
CYFUS_RS07395	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CYFUS_RS07430	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CYFUS_RS07450	COG0339	signal peptide processing
CYFUS_RS07470	COG2264	protein methyltransferase activity
CYFUS_RS07490	COG2204	response regulator
CYFUS_RS07495	COG1902	pentaerythritol trinitrate reductase activity
CYFUS_RS07500	COG3852	Histidine kinase
CYFUS_RS07520	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CYFUS_RS07535	COG2264	protein methyltransferase activity
CYFUS_RS07565	COG0612	Peptidase, M16
CYFUS_RS07575	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CYFUS_RS07585	COG3047	cAMP biosynthetic process
CYFUS_RS07585	COG2885	chlorophyll binding
CYFUS_RS07605	COG1278	Cold shock
CYFUS_RS07640	COG1181	Belongs to the D-alanine--D-alanine ligase family
CYFUS_RS07645	COG1309	transcriptional regulator
CYFUS_RS07660	COG2267	carboxylic ester hydrolase activity
CYFUS_RS07670	COG2205	protein histidine kinase activity
CYFUS_RS07695	COG0719	Fe-S assembly protein
CYFUS_RS07700	COG0396	ATPase activity
CYFUS_RS07705	COG0719	Fe-S assembly protein
CYFUS_RS07715	COG0822	iron-sulfur transferase activity
CYFUS_RS07720	COG2151	metal-sulfur cluster biosynthetic enzyme
CYFUS_RS07725	COG1024	Enoyl-CoA hydratase
CYFUS_RS07735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CYFUS_RS07820	COG1733	regulation of RNA biosynthetic process
CYFUS_RS07825	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS07840	COG0318	PFAM AMP-dependent synthetase and ligase
CYFUS_RS07935	COG1733	regulation of RNA biosynthetic process
CYFUS_RS07960	COG1309	transcriptional regulator
CYFUS_RS07970	COG0583	DNA-binding transcription factor activity
CYFUS_RS08040	COG0583	DNA-binding transcription factor activity
CYFUS_RS08105	COG2373	Large extracellular alpha-helical protein
CYFUS_RS08135	COG5002	protein histidine kinase activity
CYFUS_RS08140	COG2204	response regulator
CYFUS_RS08145	COG0432	Pfam Uncharacterised protein family UPF0047
CYFUS_RS08165	COG2124	cytochrome p450
CYFUS_RS08170	COG1846	Transcriptional regulator
CYFUS_RS08220	COG0681	Belongs to the peptidase S26 family
CYFUS_RS08225	COG0693	protein deglycase activity
CYFUS_RS08265	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CYFUS_RS08285	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CYFUS_RS08290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CYFUS_RS08330	COG2085	NADP oxidoreductase coenzyme F420-dependent
CYFUS_RS08335	COG1846	Transcriptional regulator
CYFUS_RS08365	COG2815	serine threonine protein kinase
CYFUS_RS08365	COG0515	serine threonine protein kinase
CYFUS_RS08375	COG2204	response regulator
CYFUS_RS08380	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CYFUS_RS08395	COG5652	VanZ like family
CYFUS_RS08460	COG0515	serine threonine protein kinase
CYFUS_RS08460	COG2815	serine threonine protein kinase
CYFUS_RS08470	COG0758	DNA mediated transformation
CYFUS_RS08675	COG0556	nucleotide-excision repair
CYFUS_RS08695	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CYFUS_RS08705	COG0596	Alpha beta hydrolase
CYFUS_RS08750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CYFUS_RS08815	COG0038	chloride channel
CYFUS_RS08825	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CYFUS_RS08830	COG0402	S-adenosylhomocysteine deaminase activity
CYFUS_RS08840	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CYFUS_RS08855	COG1040	competence protein
CYFUS_RS08870	COG0205	6-phosphofructokinase activity
CYFUS_RS08900	COG1280	lysine exporter protein (LysE YggA)
CYFUS_RS08975	COG1690	Belongs to the RtcB family
CYFUS_RS08980	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CYFUS_RS09015	COG1309	transcriptional regulator
CYFUS_RS09040	COG2197	response regulator
CYFUS_RS09045	COG4251	negative regulation of phosphorylation
CYFUS_RS09050	COG3852	Histidine kinase
CYFUS_RS09115	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CYFUS_RS09125	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CYFUS_RS09130	COG0156	8-amino-7-oxononanoate synthase activity
CYFUS_RS09135	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CYFUS_RS09145	COG0436	Aminotransferase
CYFUS_RS09155	COG1297	OPT oligopeptide transporter protein
CYFUS_RS09165	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS09180	COG4221	oxidoreductase activity
CYFUS_RS09180	COG3321	synthase
CYFUS_RS09180	COG0300	oxidoreductase activity
CYFUS_RS09180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CYFUS_RS09190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CYFUS_RS09190	COG3321	synthase
CYFUS_RS09215	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CYFUS_RS09220	COG3273	potassium ion transport
CYFUS_RS09220	COG0471	metal ion transport
CYFUS_RS09230	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CYFUS_RS09235	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CYFUS_RS09240	COG2080	2 iron, 2 sulfur cluster binding
CYFUS_RS09260	COG2062	phosphohistidine phosphatase, SixA
CYFUS_RS09280	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CYFUS_RS09300	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CYFUS_RS09305	COG0835	chemotaxis
CYFUS_RS09310	COG0840	transmembrane signaling receptor activity
CYFUS_RS09315	COG2198	Histidine kinase
CYFUS_RS09315	COG0643	Histidine kinase
CYFUS_RS09325	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CYFUS_RS09335	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CYFUS_RS09340	COG5001	Diguanylate cyclase
CYFUS_RS09365	COG2815	serine threonine protein kinase
CYFUS_RS09365	COG0515	serine threonine protein kinase
CYFUS_RS09395	COG1201	RNA secondary structure unwinding
CYFUS_RS09400	COG1793	dna ligase
CYFUS_RS09405	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CYFUS_RS09405	COG1793	dna ligase
CYFUS_RS09415	COG1940	carbohydrate kinase activity
CYFUS_RS09430	COG0720	synthase
CYFUS_RS09435	COG2308	Evidence 4 Homologs of previously reported genes of
CYFUS_RS09445	COG0121	glutamine amidotransferase
CYFUS_RS09450	COG1335	isochorismatase
CYFUS_RS09525	COG3275	phosphorelay sensor kinase activity
CYFUS_RS09540	COG2815	serine threonine protein kinase
CYFUS_RS09540	COG0515	serine threonine protein kinase
CYFUS_RS09550	COG3275	phosphorelay sensor kinase activity
CYFUS_RS09565	COG0297	glycogen (starch) synthase activity
CYFUS_RS09570	COG0515	serine threonine protein kinase
CYFUS_RS09570	COG2815	serine threonine protein kinase
CYFUS_RS09600	COG1834	amidinotransferase
CYFUS_RS09615	COG3250	beta-galactosidase activity
CYFUS_RS09645	COG4651	solute:proton antiporter activity
CYFUS_RS09645	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CYFUS_RS09675	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CYFUS_RS09755	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS09770	COG5002	protein histidine kinase activity
CYFUS_RS09795	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CYFUS_RS09820	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CYFUS_RS09840	COG1716	ATPase activity
CYFUS_RS09845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CYFUS_RS09875	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CYFUS_RS09880	COG0596	Alpha beta hydrolase
CYFUS_RS09890	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CYFUS_RS09900	COG0667	Aldo Keto reductase
CYFUS_RS09945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CYFUS_RS09970	COG0666	response to abiotic stimulus
CYFUS_RS09985	COG0515	serine threonine protein kinase
CYFUS_RS09985	COG2815	serine threonine protein kinase
CYFUS_RS10005	COG1366	Belongs to the anti-sigma-factor antagonist family
CYFUS_RS10015	COG2205	protein histidine kinase activity
CYFUS_RS10015	COG0784	Response regulator, receiver
CYFUS_RS10025	COG0583	DNA-binding transcription factor activity
CYFUS_RS10035	COG5464	transposase or invertase
CYFUS_RS10040	COG0346	lactoylglutathione lyase activity
CYFUS_RS10055	COG2124	cytochrome p450
CYFUS_RS10060	COG2124	cytochrome p450
CYFUS_RS10070	COG0330	HflC and HflK could
CYFUS_RS10085	COG0366	Alpha amylase catalytic
CYFUS_RS10085	COG1470	cell adhesion involved in biofilm formation
CYFUS_RS10100	COG5297	Belongs to the glycosyl hydrolase family 6
CYFUS_RS10135	COG0515	serine threonine protein kinase
CYFUS_RS10135	COG2815	serine threonine protein kinase
CYFUS_RS10140	COG4191	Histidine kinase
CYFUS_RS10140	COG0784	Response regulator, receiver
CYFUS_RS10150	COG0515	serine threonine protein kinase
CYFUS_RS10195	COG0788	formyltetrahydrofolate deformylase activity
CYFUS_RS10225	COG0405	Gamma-glutamyltransferase
CYFUS_RS10230	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CYFUS_RS10235	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CYFUS_RS10245	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CYFUS_RS10275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CYFUS_RS10280	COG4948	Mandelate Racemase Muconate Lactonizing
CYFUS_RS10305	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CYFUS_RS10360	COG0667	Aldo Keto reductase
CYFUS_RS10370	COG0326	Molecular chaperone. Has ATPase activity
CYFUS_RS10380	COG0477	Major facilitator Superfamily
CYFUS_RS10390	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CYFUS_RS10400	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CYFUS_RS10405	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CYFUS_RS10410	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CYFUS_RS10410	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CYFUS_RS10415	COG0515	serine threonine protein kinase
CYFUS_RS10450	COG0596	Alpha beta hydrolase
CYFUS_RS10460	COG1129	ABC transporter
CYFUS_RS10470	COG0300	oxidoreductase activity
CYFUS_RS10495	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS10545	COG0564	pseudouridine synthase activity
CYFUS_RS10560	COG0402	S-adenosylhomocysteine deaminase activity
CYFUS_RS10565	COG4977	sequence-specific DNA binding
CYFUS_RS10580	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CYFUS_RS10605	COG1902	pentaerythritol trinitrate reductase activity
CYFUS_RS10610	COG1959	2 iron, 2 sulfur cluster binding
CYFUS_RS10640	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CYFUS_RS10645	COG0484	heat shock protein binding
CYFUS_RS10650	COG0242	peptide deformylase activity
CYFUS_RS10655	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CYFUS_RS10665	COG0739	heme binding
CYFUS_RS10670	COG0776	regulation of translation
CYFUS_RS10690	COG1183	phosphatidylcholine synthase activity
CYFUS_RS10695	COG1058	Belongs to the CinA family
CYFUS_RS10695	COG1546	Belongs to the CinA family
CYFUS_RS10715	COG0606	chelatase, subunit chli
CYFUS_RS10785	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CYFUS_RS10790	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CYFUS_RS10790	COG0116	Belongs to the methyltransferase superfamily
CYFUS_RS10795	COG2814	Major facilitator Superfamily
CYFUS_RS10815	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CYFUS_RS10820	COG0154	amidase activity
CYFUS_RS10825	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CYFUS_RS10860	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CYFUS_RS10865	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CYFUS_RS10870	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CYFUS_RS10875	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CYFUS_RS10890	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CYFUS_RS10900	COG1666	GTP binding
CYFUS_RS10910	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS10950	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CYFUS_RS11040	COG1072	(Pantothenic acid kinase))
CYFUS_RS11070	COG0542	response to heat
CYFUS_RS11135	COG4251	negative regulation of phosphorylation
CYFUS_RS11145	COG5002	protein histidine kinase activity
CYFUS_RS11150	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CYFUS_RS11165	COG0702	epimerase
CYFUS_RS11185	COG0534	Mate efflux family protein
CYFUS_RS11190	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CYFUS_RS11205	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CYFUS_RS11215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CYFUS_RS11220	COG0318	PFAM AMP-dependent synthetase and ligase
CYFUS_RS11235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CYFUS_RS11260	COG2967	ApaG domain
CYFUS_RS11265	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CYFUS_RS11275	COG0009	L-threonylcarbamoyladenylate synthase
CYFUS_RS11320	COG1082	Xylose isomerase domain protein TIM barrel
CYFUS_RS11335	COG2022	thiamine diphosphate biosynthetic process
CYFUS_RS11355	COG3240	lipase activity
CYFUS_RS11385	COG0471	metal ion transport
CYFUS_RS11395	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CYFUS_RS11415	COG4999	Histidine kinase
CYFUS_RS11415	COG3850	Histidine kinase
CYFUS_RS11415	COG3437	response regulator, receiver
CYFUS_RS11415	COG2205	protein histidine kinase activity
CYFUS_RS11420	COG3507	Belongs to the glycosyl hydrolase 43 family
CYFUS_RS11445	COG1959	2 iron, 2 sulfur cluster binding
CYFUS_RS11455	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS11465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CYFUS_RS11525	COG0723	plastoquinol--plastocyanin reductase activity
CYFUS_RS11525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CYFUS_RS11530	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CYFUS_RS11545	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CYFUS_RS11565	COG2205	protein histidine kinase activity
CYFUS_RS11570	COG3228	Belongs to the MtfA family
CYFUS_RS11580	COG0753	catalase activity
CYFUS_RS11600	COG2124	cytochrome p450
CYFUS_RS11605	COG2815	serine threonine protein kinase
CYFUS_RS11605	COG0515	serine threonine protein kinase
CYFUS_RS11615	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS11620	COG2207	Transcriptional regulator
CYFUS_RS11660	COG0346	lactoylglutathione lyase activity
CYFUS_RS11670	COG1111	helicase
CYFUS_RS11670	COG1205	dead DEAH box helicase
CYFUS_RS11675	COG3359	exonuclease
CYFUS_RS11685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CYFUS_RS11685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CYFUS_RS11710	COG1309	transcriptional regulator
CYFUS_RS11720	COG3590	peptidase
CYFUS_RS11725	COG1505	serine-type exopeptidase activity
CYFUS_RS11730	COG0783	Belongs to the Dps family
CYFUS_RS11735	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CYFUS_RS11740	COG0450	alkyl hydroperoxide reductase
CYFUS_RS11745	COG3604	Transcriptional regulator
CYFUS_RS11765	COG5002	protein histidine kinase activity
CYFUS_RS11775	COG0739	heme binding
CYFUS_RS11775	COG0741	lytic transglycosylase activity
CYFUS_RS11775	COG1196	nuclear chromosome segregation
CYFUS_RS11780	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CYFUS_RS11785	COG3854	ATPases associated with a variety of cellular activities
CYFUS_RS11810	COG1271	oxidase subunit
CYFUS_RS11855	COG0318	PFAM AMP-dependent synthetase and ligase
CYFUS_RS11880	COG1238	metal cluster binding
CYFUS_RS11905	COG0657	acetylesterase activity
CYFUS_RS11930	COG1472	Belongs to the glycosyl hydrolase 3 family
CYFUS_RS11960	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CYFUS_RS12005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CYFUS_RS12015	COG1472	Belongs to the glycosyl hydrolase 3 family
CYFUS_RS12020	COG0318	PFAM AMP-dependent synthetase and ligase
CYFUS_RS12030	COG5002	protein histidine kinase activity
CYFUS_RS12035	COG1472	Belongs to the glycosyl hydrolase 3 family
CYFUS_RS12040	COG0747	negative chemotaxis
CYFUS_RS12090	COG0300	oxidoreductase activity
CYFUS_RS12100	COG1024	Enoyl-CoA hydratase
CYFUS_RS12120	COG0667	Aldo Keto reductase
CYFUS_RS12130	COG0583	DNA-binding transcription factor activity
CYFUS_RS12160	COG3275	phosphorelay sensor kinase activity
CYFUS_RS12180	COG0640	Transcriptional regulator
CYFUS_RS12240	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CYFUS_RS12240	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CYFUS_RS12245	COG1619	proteins homologs of microcin C7 resistance protein MccF
CYFUS_RS12250	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CYFUS_RS12255	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CYFUS_RS12260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CYFUS_RS12270	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CYFUS_RS12275	COG1100	Small GTP-binding protein
CYFUS_RS12285	COG0515	serine threonine protein kinase
CYFUS_RS12290	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CYFUS_RS12295	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CYFUS_RS12305	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CYFUS_RS12330	COG0590	tRNA wobble adenosine to inosine editing
CYFUS_RS12350	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CYFUS_RS12375	COG0515	serine threonine protein kinase
CYFUS_RS12375	COG2815	serine threonine protein kinase
CYFUS_RS12385	COG0204	Acyl-transferase
CYFUS_RS12405	COG0534	Mate efflux family protein
CYFUS_RS12505	COG0514	ATP-dependent DNA helicase (RecQ)
CYFUS_RS12515	COG2003	Belongs to the UPF0758 family
CYFUS_RS12525	COG1362	aminopeptidase activity
CYFUS_RS12595	COG2124	cytochrome p450
CYFUS_RS12600	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CYFUS_RS12670	COG1301	dicarboxylic acid transport
CYFUS_RS12675	COG1047	Peptidyl-prolyl cis-trans
CYFUS_RS12730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CYFUS_RS12745	COG2311	Membrane
CYFUS_RS12760	COG3209	COG3209 Rhs family protein
CYFUS_RS12765	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CYFUS_RS12795	COG0515	serine threonine protein kinase
CYFUS_RS12855	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CYFUS_RS12895	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CYFUS_RS12905	COG1011	Hydrolase
CYFUS_RS12910	COG0596	Alpha beta hydrolase
CYFUS_RS12915	COG2208	phosphoserine phosphatase activity
CYFUS_RS12960	COG2205	protein histidine kinase activity
CYFUS_RS12995	COG1309	transcriptional regulator
CYFUS_RS13010	COG1136	(ABC) transporter
CYFUS_RS13015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CYFUS_RS13025	COG2226	methyltransferase
CYFUS_RS13040	COG0483	inositol monophosphate 1-phosphatase activity
CYFUS_RS13060	COG0667	Aldo Keto reductase
CYFUS_RS13105	COG0535	radical SAM domain protein
CYFUS_RS13115	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
CYFUS_RS13120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CYFUS_RS13130	COG1025	Belongs to the peptidase M16 family
CYFUS_RS13150	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS13155	COG0515	serine threonine protein kinase
CYFUS_RS13165	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CYFUS_RS13170	COG0277	FAD linked oxidase domain protein
CYFUS_RS13175	COG0488	(ABC) transporter
CYFUS_RS13180	COG1733	regulation of RNA biosynthetic process
CYFUS_RS13195	COG0477	Major facilitator Superfamily
CYFUS_RS13210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CYFUS_RS13215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CYFUS_RS13230	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS13245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CYFUS_RS13280	COG0488	(ABC) transporter
CYFUS_RS13285	COG0513	Belongs to the DEAD box helicase family
CYFUS_RS13290	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CYFUS_RS13295	COG1187	pseudouridine synthase activity
CYFUS_RS13315	COG4977	sequence-specific DNA binding
CYFUS_RS13355	COG0515	serine threonine protein kinase
CYFUS_RS13355	COG2815	serine threonine protein kinase
CYFUS_RS13365	COG2373	Large extracellular alpha-helical protein
CYFUS_RS13370	COG4953	penicillin-binding protein 1C
CYFUS_RS13420	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CYFUS_RS13425	COG0583	DNA-binding transcription factor activity
CYFUS_RS13480	COG0515	serine threonine protein kinase
CYFUS_RS13505	COG1063	alcohol dehydrogenase
CYFUS_RS13565	COG0583	DNA-binding transcription factor activity
CYFUS_RS13580	COG2815	serine threonine protein kinase
CYFUS_RS13580	COG0515	serine threonine protein kinase
CYFUS_RS13595	COG5002	protein histidine kinase activity
CYFUS_RS13620	COG5337	Spore coat protein CotH
CYFUS_RS13630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CYFUS_RS13650	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CYFUS_RS13685	COG1191	sigma factor activity
CYFUS_RS13705	COG1317	bacterial-type flagellum organization
CYFUS_RS13710	COG1157	protein secretion by the type III secretion system
CYFUS_RS13725	COG1776	CheC inhibitor of MCP methylation
CYFUS_RS13725	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CYFUS_RS13735	COG4790	Type iii secretion
CYFUS_RS13740	COG1987	bacterial-type flagellum assembly
CYFUS_RS13755	COG2257	FlhB HrpN YscU SpaS Family
CYFUS_RS13800	COG0457	Tetratricopeptide repeat
CYFUS_RS13805	COG4789	Type iii secretion
CYFUS_RS13810	COG1716	ATPase activity
CYFUS_RS13825	COG1714	RDD family
CYFUS_RS13880	COG0714	Associated with various cellular activities
CYFUS_RS13915	COG3973	AAA domain
CYFUS_RS13945	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CYFUS_RS13955	COG3507	Belongs to the glycosyl hydrolase 43 family
CYFUS_RS13970	COG0596	Alpha beta hydrolase
CYFUS_RS13985	COG1472	Belongs to the glycosyl hydrolase 3 family
CYFUS_RS14025	COG0515	serine threonine protein kinase
CYFUS_RS14035	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CYFUS_RS14040	COG0616	signal peptide processing
CYFUS_RS14055	COG0187	DNA topoisomerase II activity
CYFUS_RS14060	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CYFUS_RS14070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CYFUS_RS14085	COG1595	DNA-templated transcription, initiation
CYFUS_RS14095	COG2223	nitrite transmembrane transporter activity
CYFUS_RS14155	COG1459	type II secretion system
CYFUS_RS14160	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CYFUS_RS14205	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CYFUS_RS14240	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CYFUS_RS14245	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CYFUS_RS14280	COG0416	fatty acid biosynthetic process
CYFUS_RS14300	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CYFUS_RS14305	COG0617	tRNA 3'-terminal CCA addition
CYFUS_RS14310	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CYFUS_RS14315	COG0564	pseudouridine synthase activity
CYFUS_RS14365	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CYFUS_RS14370	COG4589	Belongs to the CDS family
CYFUS_RS14375	COG0750	zinc metalloprotease
CYFUS_RS14380	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CYFUS_RS14385	COG1214	PFAM Peptidase M22, glycoprotease
CYFUS_RS14395	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CYFUS_RS14415	COG0314	molybdopterin synthase activity
CYFUS_RS14445	COG0750	zinc metalloprotease
CYFUS_RS14460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CYFUS_RS14465	COG1546	Belongs to the CinA family
CYFUS_RS14465	COG1058	Belongs to the CinA family
CYFUS_RS14490	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CYFUS_RS14510	COG2850	peptidyl-arginine hydroxylation
CYFUS_RS14545	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CYFUS_RS14545	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CYFUS_RS14560	COG1131	(ABC) transporter
CYFUS_RS14585	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CYFUS_RS14605	COG0515	serine threonine protein kinase
CYFUS_RS14615	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CYFUS_RS14620	COG0316	Belongs to the HesB IscA family
CYFUS_RS14675	COG3153	acetyltransferase
CYFUS_RS14680	COG0297	glycogen (starch) synthase activity
CYFUS_RS14680	COG0438	transferase activity, transferring glycosyl groups
CYFUS_RS14690	COG0438	transferase activity, transferring glycosyl groups
CYFUS_RS14695	COG2205	protein histidine kinase activity
CYFUS_RS14695	COG0784	Response regulator, receiver
CYFUS_RS14695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CYFUS_RS14695	COG2198	Histidine kinase
CYFUS_RS14710	COG0667	Aldo Keto reductase
CYFUS_RS14740	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CYFUS_RS14770	COG0588	phosphoglycerate mutase activity
CYFUS_RS14775	COG1607	acyl-coa hydrolase
CYFUS_RS14785	COG0584	glycerophosphoryl diester phosphodiesterase
CYFUS_RS14815	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CYFUS_RS14835	COG3104	oligopeptide transport
CYFUS_RS14855	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS14880	COG0318	PFAM AMP-dependent synthetase and ligase
CYFUS_RS14890	COG3848	Pyruvate phosphate dikinase
CYFUS_RS14890	COG0574	Belongs to the PEP-utilizing enzyme family
CYFUS_RS14915	COG1074	ATP-dependent DNA helicase activity
CYFUS_RS14920	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CYFUS_RS14950	COG0658	competence protein
CYFUS_RS14950	COG2333	competence protein COMEC
CYFUS_RS14955	COG1329	Transcriptional regulator
CYFUS_RS14960	COG1716	ATPase activity
CYFUS_RS14965	COG0215	cysteine-tRNA ligase activity
CYFUS_RS14975	COG4124	Belongs to the glycosyl hydrolase 26 family
CYFUS_RS14990	COG4251	negative regulation of phosphorylation
CYFUS_RS14995	COG5002	protein histidine kinase activity
CYFUS_RS15000	COG0077	Prephenate dehydratase
CYFUS_RS15005	COG0077	Prephenate dehydratase
CYFUS_RS15005	COG1605	Chorismate mutase
CYFUS_RS15030	COG0556	nucleotide-excision repair
CYFUS_RS15035	COG0322	excinuclease ABC activity
CYFUS_RS15080	COG0424	maF-like protein
CYFUS_RS15085	COG5001	Diguanylate cyclase
CYFUS_RS15085	COG3706	GGDEF domain
CYFUS_RS15085	COG2203	Gaf domain
CYFUS_RS15085	COG4251	negative regulation of phosphorylation
CYFUS_RS15090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CYFUS_RS15105	COG0768	penicillin binding
CYFUS_RS15110	COG0772	Belongs to the SEDS family
CYFUS_RS15115	COG2239	Acts as a magnesium transporter
CYFUS_RS15125	COG3118	belongs to the thioredoxin family
CYFUS_RS15135	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CYFUS_RS15140	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CYFUS_RS15145	COG0181	hydroxymethylbilane synthase activity
CYFUS_RS15155	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CYFUS_RS15160	COG0312	modulator of DNA gyrase
CYFUS_RS15165	COG0312	modulator of DNA gyrase
CYFUS_RS15185	COG4989	oxidoreductase activity
CYFUS_RS15225	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CYFUS_RS15230	COG0508	dehydrogenase complex catalyzes the overall conversion of
CYFUS_RS15230	COG0022	dehydrogenase e1 component
CYFUS_RS15235	COG0508	dehydrogenase complex catalyzes the overall conversion of
CYFUS_RS15250	COG3852	Histidine kinase
CYFUS_RS15285	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CYFUS_RS15325	COG0784	Response regulator, receiver
CYFUS_RS15360	COG3227	Zinc metalloprotease (Elastase)
CYFUS_RS15365	COG5002	protein histidine kinase activity
CYFUS_RS15385	COG2267	carboxylic ester hydrolase activity
CYFUS_RS15390	COG0586	Pfam SNARE associated Golgi protein
CYFUS_RS15420	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CYFUS_RS15425	COG4221	oxidoreductase activity
CYFUS_RS15430	COG0312	modulator of DNA gyrase
CYFUS_RS15465	COG2755	lipolytic protein G-D-S-L family
CYFUS_RS15465	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CYFUS_RS15480	COG0784	Response regulator, receiver
CYFUS_RS15480	COG2205	protein histidine kinase activity
CYFUS_RS15495	COG1401	restriction endodeoxyribonuclease activity
CYFUS_RS15500	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CYFUS_RS15505	COG5002	protein histidine kinase activity
CYFUS_RS15520	COG5002	protein histidine kinase activity
CYFUS_RS15540	COG1733	regulation of RNA biosynthetic process
CYFUS_RS15545	COG1752	Esterase of the alpha-beta hydrolase superfamily
CYFUS_RS15555	COG2226	methyltransferase
CYFUS_RS15635	COG1999	signal sequence binding
CYFUS_RS15685	COG0823	Involved in the tonB-independent uptake of proteins
CYFUS_RS15735	COG1760	l-serine dehydratase
CYFUS_RS15745	COG2855	membrane
CYFUS_RS15775	COG5564	TIM-barrel signal transduction protein
CYFUS_RS15780	COG5441	Belongs to the UPF0261 family
CYFUS_RS15820	COG3157	Type VI secretion system effector, Hcp
CYFUS_RS15895	COG3209	COG3209 Rhs family protein
CYFUS_RS15895	COG3209	COG3209 Rhs family protein
CYFUS_RS15960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CYFUS_RS15965	COG0697	spore germination
CYFUS_RS15975	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CYFUS_RS15980	COG0527	aspartate kinase activity
CYFUS_RS15985	COG4865	methylaspartate mutase activity
CYFUS_RS16020	COG1100	Small GTP-binding protein
CYFUS_RS16025	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CYFUS_RS16060	COG0604	alcohol dehydrogenase
CYFUS_RS16090	COG2175	clavaminate synthase activity
CYFUS_RS16105	COG5002	protein histidine kinase activity
CYFUS_RS16135	COG0667	Aldo Keto reductase
CYFUS_RS16140	COG0515	serine threonine protein kinase
CYFUS_RS16140	COG2815	serine threonine protein kinase
CYFUS_RS16150	COG2124	cytochrome p450
CYFUS_RS16160	COG1819	glycosyl
CYFUS_RS16170	COG0154	amidase activity
CYFUS_RS16290	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CYFUS_RS16295	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CYFUS_RS16300	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CYFUS_RS16310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CYFUS_RS16315	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CYFUS_RS16320	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CYFUS_RS16330	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CYFUS_RS16335	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CYFUS_RS16340	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CYFUS_RS16345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CYFUS_RS16355	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CYFUS_RS16375	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CYFUS_RS16380	COG1396	sequence-specific DNA binding
CYFUS_RS16390	COG1309	transcriptional regulator
CYFUS_RS16395	COG1024	Enoyl-CoA hydratase
CYFUS_RS16400	COG0739	heme binding
CYFUS_RS16455	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYFUS_RS16460	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CYFUS_RS16465	COG1034	ATP synthesis coupled electron transport
CYFUS_RS16470	COG0649	NAD binding
CYFUS_RS16475	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYFUS_RS16490	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYFUS_RS16495	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYFUS_RS16505	COG2124	cytochrome p450
CYFUS_RS16510	COG0613	PHP domain protein
CYFUS_RS16520	COG1899	peptidyl-lysine modification to peptidyl-hypusine
CYFUS_RS16555	COG2860	membrane
CYFUS_RS16560	COG0583	DNA-binding transcription factor activity
CYFUS_RS16565	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS16570	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CYFUS_RS16600	COG4941	Belongs to the sigma-70 factor family
CYFUS_RS16605	COG3795	YCII-related domain
CYFUS_RS16615	COG3537	Alpha-1,2-mannosidase
CYFUS_RS16650	COG1024	Enoyl-CoA hydratase
CYFUS_RS16665	COG1166	arginine decarboxylase activity
CYFUS_RS16670	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CYFUS_RS16680	COG0484	heat shock protein binding
CYFUS_RS16685	COG0443	Heat shock 70 kDa protein
CYFUS_RS16700	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CYFUS_RS16700	COG1796	DNA polymerase
CYFUS_RS16710	COG0521	Mo-molybdopterin cofactor biosynthetic process
CYFUS_RS16785	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CYFUS_RS16820	COG1959	2 iron, 2 sulfur cluster binding
CYFUS_RS16825	COG2319	Wd-40 repeat
CYFUS_RS16825	COG4249	Peptidase C14 caspase catalytic subunit p20
CYFUS_RS16840	COG1309	transcriptional regulator
CYFUS_RS16865	COG2267	carboxylic ester hydrolase activity
CYFUS_RS16875	COG0243	molybdopterin cofactor binding
CYFUS_RS16895	COG2814	Major facilitator Superfamily
CYFUS_RS16905	COG0633	Ferredoxin
CYFUS_RS16920	COG2072	flavoprotein involved in K transport
CYFUS_RS16950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CYFUS_RS16950	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CYFUS_RS16960	COG0084	hydrolase, TatD family'
CYFUS_RS16970	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CYFUS_RS16980	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CYFUS_RS16990	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CYFUS_RS17000	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CYFUS_RS17010	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CYFUS_RS17015	COG0126	phosphoglycerate kinase activity
CYFUS_RS17020	COG0149	triose-phosphate isomerase activity
CYFUS_RS17100	COG0318	PFAM AMP-dependent synthetase and ligase
CYFUS_RS17130	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS17150	COG2204	response regulator
CYFUS_RS17155	COG4191	Histidine kinase
CYFUS_RS17195	COG2890	protein-(glutamine-N5) methyltransferase activity
CYFUS_RS17205	COG4106	trans-aconitate 2-methyltransferase activity
CYFUS_RS17220	COG0457	Tetratricopeptide repeat
CYFUS_RS17220	COG0515	serine threonine protein kinase
CYFUS_RS17230	COG4191	Histidine kinase
CYFUS_RS17235	COG1183	phosphatidylcholine synthase activity
CYFUS_RS17250	COG0515	serine threonine protein kinase
CYFUS_RS17260	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CYFUS_RS17265	COG0138	bifunctional purine biosynthesis protein purh
CYFUS_RS17275	COG0151	Belongs to the GarS family
CYFUS_RS17280	COG0795	lipopolysaccharide-transporting ATPase activity
CYFUS_RS17305	COG0322	excinuclease ABC activity
CYFUS_RS17310	COG0438	transferase activity, transferring glycosyl groups
CYFUS_RS17315	COG0297	glycogen (starch) synthase activity
CYFUS_RS17320	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CYFUS_RS17325	COG1215	transferase activity, transferring glycosyl groups
CYFUS_RS17335	COG2204	response regulator
CYFUS_RS17340	COG1309	transcriptional regulator
CYFUS_RS17400	COG1733	regulation of RNA biosynthetic process
CYFUS_RS17465	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CYFUS_RS17475	COG0704	Plays a role in the regulation of phosphate uptake
CYFUS_RS17480	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CYFUS_RS17485	COG0581	inorganic phosphate transmembrane transporter activity
CYFUS_RS17490	COG0573	inorganic phosphate transmembrane transporter activity
CYFUS_RS17495	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CYFUS_RS17510	COG5002	protein histidine kinase activity
CYFUS_RS17515	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS17530	COG1399	metal-binding, possibly nucleic acid-binding protein
CYFUS_RS17535	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CYFUS_RS17540	COG0416	fatty acid biosynthetic process
CYFUS_RS17545	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CYFUS_RS17555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CYFUS_RS17560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CYFUS_RS17565	COG0698	ribose 5-phosphate isomerase
CYFUS_RS17570	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CYFUS_RS17575	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CYFUS_RS17580	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CYFUS_RS17580	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CYFUS_RS17590	COG2124	cytochrome p450
CYFUS_RS17600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CYFUS_RS17605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CYFUS_RS17615	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CYFUS_RS17615	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CYFUS_RS17620	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CYFUS_RS17625	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CYFUS_RS17635	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS17640	COG2198	Histidine kinase
CYFUS_RS17640	COG0643	Histidine kinase
CYFUS_RS17640	COG0784	Response regulator, receiver
CYFUS_RS17640	COG0784	Response regulator, receiver
CYFUS_RS17640	COG0643	Histidine kinase
CYFUS_RS17640	COG2198	Histidine kinase
CYFUS_RS17650	COG0835	chemotaxis
CYFUS_RS17665	COG2201	protein-glutamate methylesterase activity
CYFUS_RS17715	COG2226	methyltransferase
CYFUS_RS17735	COG1672	PFAM Archaeal ATPase
CYFUS_RS17735	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CYFUS_RS17750	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS17755	COG0495	leucyl-tRNA aminoacylation
CYFUS_RS17765	COG0268	Binds directly to 16S ribosomal RNA
CYFUS_RS17770	COG3956	TIGRFAM MazG family protein
CYFUS_RS17780	COG0457	Tetratricopeptide repeat
CYFUS_RS17790	COG1480	7TM receptor with intracellular HD hydrolase
CYFUS_RS17795	COG0662	Cupin 2, conserved barrel domain protein
CYFUS_RS17795	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CYFUS_RS17820	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CYFUS_RS17830	COG1136	(ABC) transporter
CYFUS_RS17835	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CYFUS_RS17845	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CYFUS_RS17850	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CYFUS_RS17855	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CYFUS_RS17870	COG2095	MarC family integral membrane protein
CYFUS_RS17875	COG0463	Glycosyl transferase, family 2
CYFUS_RS17880	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CYFUS_RS17890	COG1132	(ABC) transporter
CYFUS_RS17900	COG1519	Transferase
CYFUS_RS17910	COG1663	tetraacyldisaccharide 4'-kinase activity
CYFUS_RS17915	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CYFUS_RS17915	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CYFUS_RS17920	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CYFUS_RS17920	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CYFUS_RS17935	COG1561	YicC-like family, N-terminal region
CYFUS_RS17940	COG0194	GDP metabolic process
CYFUS_RS17970	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CYFUS_RS18000	COG1690	Belongs to the RtcB family
CYFUS_RS18005	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CYFUS_RS18015	COG2204	response regulator
CYFUS_RS18020	COG0515	serine threonine protein kinase
CYFUS_RS18020	COG2815	serine threonine protein kinase
CYFUS_RS18040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CYFUS_RS18060	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CYFUS_RS18070	COG0583	DNA-binding transcription factor activity
CYFUS_RS18110	COG0515	serine threonine protein kinase
CYFUS_RS18155	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS18160	COG0583	DNA-binding transcription factor activity
CYFUS_RS18195	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CYFUS_RS18200	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CYFUS_RS18205	COG2921	Belongs to the UPF0250 family
CYFUS_RS18220	COG0443	Heat shock 70 kDa protein
CYFUS_RS18240	COG2376	Dihydroxyacetone kinase
CYFUS_RS18300	COG0515	serine threonine protein kinase
CYFUS_RS18340	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CYFUS_RS18340	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CYFUS_RS18345	COG1131	(ABC) transporter
CYFUS_RS18370	COG3706	GGDEF domain
CYFUS_RS18375	COG2204	response regulator
CYFUS_RS18385	COG1070	Carbohydrate kinase
CYFUS_RS18390	COG0419	ATPase involved in DNA repair
CYFUS_RS18410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CYFUS_RS18415	COG0246	Mannitol dehydrogenase
CYFUS_RS18445	COG3852	Histidine kinase
CYFUS_RS18450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CYFUS_RS18460	COG1595	DNA-templated transcription, initiation
CYFUS_RS18520	COG0693	protein deglycase activity
CYFUS_RS18540	COG0110	maltose O-acetyltransferase activity
CYFUS_RS18550	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CYFUS_RS18635	COG0489	protein tyrosine kinase activity
CYFUS_RS18640	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CYFUS_RS18645	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CYFUS_RS18695	COG4585	Histidine kinase
CYFUS_RS18700	COG2197	response regulator
CYFUS_RS18730	COG0494	nUDIX hydrolase
CYFUS_RS18750	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CYFUS_RS18755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CYFUS_RS18770	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CYFUS_RS18790	COG0667	Aldo Keto reductase
CYFUS_RS18815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CYFUS_RS18840	COG3209	COG3209 Rhs family protein
CYFUS_RS18875	COG0583	DNA-binding transcription factor activity
CYFUS_RS18880	COG0589	response to stress
CYFUS_RS18890	COG3604	Transcriptional regulator
CYFUS_RS18895	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CYFUS_RS18895	COG1017	nitric oxide dioxygenase activity
CYFUS_RS18905	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CYFUS_RS18920	COG1741	Belongs to the pirin family
CYFUS_RS18925	COG0583	DNA-binding transcription factor activity
CYFUS_RS18930	COG2205	protein histidine kinase activity
CYFUS_RS18935	COG4566	intracellular signal transduction
CYFUS_RS18935	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS18940	COG2205	protein histidine kinase activity
CYFUS_RS18945	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CYFUS_RS18970	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CYFUS_RS18975	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CYFUS_RS18980	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CYFUS_RS18985	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CYFUS_RS18990	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CYFUS_RS18995	COG0131	Imidazoleglycerol-phosphate dehydratase
CYFUS_RS19000	COG0107	imidazoleglycerol-phosphate synthase activity
CYFUS_RS19010	COG0140	phosphoribosyl-ATP diphosphatase activity
CYFUS_RS19010	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CYFUS_RS19015	COG0557	exoribonuclease II activity
CYFUS_RS19030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CYFUS_RS19035	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CYFUS_RS19060	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CYFUS_RS19060	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CYFUS_RS19075	COG0557	exoribonuclease II activity
CYFUS_RS19080	COG0513	Belongs to the DEAD box helicase family
CYFUS_RS19085	COG1193	negative regulation of DNA recombination
CYFUS_RS19100	COG3876	Protein conserved in bacteria
CYFUS_RS19110	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CYFUS_RS19125	COG0737	Belongs to the 5'-nucleotidase family
CYFUS_RS19185	COG2124	cytochrome p450
CYFUS_RS19190	COG1309	transcriptional regulator
CYFUS_RS19195	COG1652	LysM domain
CYFUS_RS19210	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CYFUS_RS19215	COG0542	response to heat
CYFUS_RS19235	COG1136	(ABC) transporter
CYFUS_RS19235	COG0577	efflux transmembrane transporter activity
CYFUS_RS19240	COG0577	efflux transmembrane transporter activity
CYFUS_RS19245	COG1136	(ABC) transporter
CYFUS_RS19245	COG0577	efflux transmembrane transporter activity
CYFUS_RS19250	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CYFUS_RS19265	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CYFUS_RS19290	COG2373	Large extracellular alpha-helical protein
CYFUS_RS19340	COG0251	oxidation-reduction process
CYFUS_RS19395	COG0572	uridine kinase
CYFUS_RS19435	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CYFUS_RS19435	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CYFUS_RS19440	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CYFUS_RS19450	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS19460	COG1595	DNA-templated transcription, initiation
CYFUS_RS19465	COG0686	Belongs to the AlaDH PNT family
CYFUS_RS19475	COG0154	amidase activity
CYFUS_RS19480	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS19545	COG0515	serine threonine protein kinase
CYFUS_RS19580	COG1131	(ABC) transporter
CYFUS_RS19590	COG0113	porphobilinogen synthase activity
CYFUS_RS19605	COG1181	Belongs to the D-alanine--D-alanine ligase family
CYFUS_RS19625	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CYFUS_RS19625	COG1672	PFAM Archaeal ATPase
CYFUS_RS19635	COG0463	Glycosyl transferase, family 2
CYFUS_RS19645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CYFUS_RS19680	COG2815	serine threonine protein kinase
CYFUS_RS19680	COG0515	serine threonine protein kinase
CYFUS_RS19715	COG4249	Peptidase C14 caspase catalytic subunit p20
CYFUS_RS19715	COG2319	Wd-40 repeat
CYFUS_RS19745	COG2409	Drug exporters of the RND superfamily
CYFUS_RS19755	COG1562	ergosterol biosynthetic process
CYFUS_RS19760	COG0071	Belongs to the small heat shock protein (HSP20) family
CYFUS_RS19780	COG1960	acyl-CoA dehydrogenase activity
CYFUS_RS19785	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
CYFUS_RS19790	COG1309	transcriptional regulator
CYFUS_RS19795	COG4191	Histidine kinase
CYFUS_RS19795	COG0784	Response regulator, receiver
CYFUS_RS19815	COG0628	permease
CYFUS_RS19825	COG2197	response regulator
CYFUS_RS19830	COG4585	Histidine kinase
CYFUS_RS19840	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CYFUS_RS19850	COG0529	Catalyzes the synthesis of activated sulfate
CYFUS_RS19850	COG2046	Belongs to the sulfate adenylyltransferase family
CYFUS_RS19855	COG1606	tRNA processing
CYFUS_RS19865	COG0701	Predicted permease
CYFUS_RS19880	COG0101	tRNA pseudouridine synthase activity
CYFUS_RS19900	COG0300	oxidoreductase activity
CYFUS_RS19910	COG0443	Heat shock 70 kDa protein
CYFUS_RS19955	COG0825	malonyl-CoA metabolic process
CYFUS_RS19960	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CYFUS_RS19975	COG0488	(ABC) transporter
CYFUS_RS19985	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CYFUS_RS20000	COG0640	Transcriptional regulator
CYFUS_RS20005	COG2124	cytochrome p450
CYFUS_RS20015	COG0515	serine threonine protein kinase
CYFUS_RS20015	COG2815	serine threonine protein kinase
CYFUS_RS20025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CYFUS_RS20070	COG2207	Transcriptional regulator
CYFUS_RS20080	COG2175	clavaminate synthase activity
CYFUS_RS20085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CYFUS_RS20090	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CYFUS_RS20095	COG4521	taurine ABC transporter
CYFUS_RS20140	COG0688	phosphatidylethanolamine metabolic process
CYFUS_RS20150	COG4181	ATPase activity
CYFUS_RS20155	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CYFUS_RS20190	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CYFUS_RS20210	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CYFUS_RS20230	COG1360	Flagellar Motor Protein
CYFUS_RS20240	COG0625	glutathione transferase activity
CYFUS_RS20245	COG0583	DNA-binding transcription factor activity
CYFUS_RS20250	COG1501	Belongs to the glycosyl hydrolase 31 family
CYFUS_RS20255	COG3279	Response regulator of the LytR AlgR family
CYFUS_RS20265	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CYFUS_RS20265	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CYFUS_RS20355	COG1484	DNA-dependent DNA replication
CYFUS_RS20380	COG0583	DNA-binding transcription factor activity
CYFUS_RS20385	COG0596	Alpha beta hydrolase
CYFUS_RS20435	COG4191	Histidine kinase
CYFUS_RS20440	COG0741	lytic transglycosylase activity
CYFUS_RS20460	COG1657	PFAM Prenyltransferase squalene oxidase
CYFUS_RS20465	COG0840	transmembrane signaling receptor activity
CYFUS_RS20485	COG5280	Phage tail tape measure protein TP901
CYFUS_RS20485	COG3953	SLT domain
CYFUS_RS20490	COG1349	DNA-binding transcription factor activity
CYFUS_RS20515	COG1921	L-seryl-tRNASec selenium transferase activity
CYFUS_RS20540	COG0564	pseudouridine synthase activity
CYFUS_RS20570	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CYFUS_RS20585	COG0714	Associated with various cellular activities
CYFUS_RS20620	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CYFUS_RS20670	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CYFUS_RS20695	COG0515	serine threonine protein kinase
CYFUS_RS20730	COG1595	DNA-templated transcription, initiation
CYFUS_RS20780	COG1215	transferase activity, transferring glycosyl groups
CYFUS_RS20800	COG2115	Belongs to the xylose isomerase family
CYFUS_RS20805	COG1070	Carbohydrate kinase
CYFUS_RS20815	COG4214	carbohydrate transport
CYFUS_RS20820	COG4213	ABC transporter substrate-binding protein
CYFUS_RS20835	COG4221	oxidoreductase activity
CYFUS_RS20855	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS20865	COG1942	4-Oxalocrotonate Tautomerase
CYFUS_RS20870	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS20890	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CYFUS_RS20895	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CYFUS_RS20900	COG2080	2 iron, 2 sulfur cluster binding
CYFUS_RS20920	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CYFUS_RS20920	COG0515	serine threonine protein kinase
CYFUS_RS20935	COG1846	Transcriptional regulator
CYFUS_RS20990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CYFUS_RS20995	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CYFUS_RS20995	COG1672	PFAM Archaeal ATPase
CYFUS_RS21070	COG0583	DNA-binding transcription factor activity
CYFUS_RS21090	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CYFUS_RS21095	COG0798	PFAM Bile acid sodium symporter
CYFUS_RS21100	COG0640	Transcriptional regulator
CYFUS_RS21115	COG1819	glycosyl
CYFUS_RS21160	COG2937	Belongs to the GPAT DAPAT family
CYFUS_RS21170	COG5002	protein histidine kinase activity
CYFUS_RS21195	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CYFUS_RS21200	COG0049	tRNA binding
CYFUS_RS21205	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CYFUS_RS21210	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CYFUS_RS21215	COG0051	transcription antitermination factor activity, RNA binding
CYFUS_RS21220	COG0088	Forms part of the polypeptide exit tunnel
CYFUS_RS21225	COG0089	rRNA binding
CYFUS_RS21230	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CYFUS_RS21235	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CYFUS_RS21240	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CYFUS_RS21245	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CYFUS_RS21250	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CYFUS_RS21255	COG0255	Belongs to the universal ribosomal protein uL29 family
CYFUS_RS21260	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CYFUS_RS21265	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CYFUS_RS21270	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CYFUS_RS21280	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CYFUS_RS21285	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CYFUS_RS21290	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CYFUS_RS21295	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CYFUS_RS21300	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CYFUS_RS21305	COG1841	ribosomal large subunit assembly
CYFUS_RS21310	COG0200	Binds to the 23S rRNA
CYFUS_RS21325	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CYFUS_RS21330	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CYFUS_RS21335	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CYFUS_RS21340	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CYFUS_RS21345	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CYFUS_RS21350	COG0202	RNA polymerase activity
CYFUS_RS21355	COG0203	ribosomal protein L17
CYFUS_RS21405	COG2313	pseudouridylate synthase activity
CYFUS_RS21410	COG0741	lytic transglycosylase activity
CYFUS_RS21455	COG3209	COG3209 Rhs family protein
CYFUS_RS21490	COG3209	COG3209 Rhs family protein
CYFUS_RS21505	COG3209	COG3209 Rhs family protein
CYFUS_RS21525	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CYFUS_RS21555	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CYFUS_RS21580	COG1228	amidohydrolase
CYFUS_RS21595	COG2205	protein histidine kinase activity
CYFUS_RS21600	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CYFUS_RS21620	COG4638	Rieske (2fe-2S)
CYFUS_RS21645	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CYFUS_RS21655	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CYFUS_RS21665	COG2264	protein methyltransferase activity
CYFUS_RS21675	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CYFUS_RS21680	COG1058	Belongs to the CinA family
CYFUS_RS21680	COG1546	Belongs to the CinA family
CYFUS_RS21685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CYFUS_RS21690	COG0017	Asparaginyl-tRNA synthetase
CYFUS_RS21750	COG0515	serine threonine protein kinase
CYFUS_RS21775	COG0217	transcriptional regulatory protein
CYFUS_RS21780	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CYFUS_RS21800	COG2084	Dehydrogenase
CYFUS_RS21810	COG2986	histidine ammonia-lyase
CYFUS_RS21815	COG0527	aspartate kinase activity
CYFUS_RS21835	COG1215	transferase activity, transferring glycosyl groups
CYFUS_RS21850	COG0443	Heat shock 70 kDa protein
CYFUS_RS21895	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CYFUS_RS21960	COG2943	transferase activity, transferring hexosyl groups
CYFUS_RS21970	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CYFUS_RS21980	COG0346	lactoylglutathione lyase activity
CYFUS_RS21990	COG1611	Belongs to the LOG family
CYFUS_RS22000	COG0667	Aldo Keto reductase
CYFUS_RS22050	COG3387	PFAM Glycoside hydrolase 15-related
CYFUS_RS22055	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CYFUS_RS22065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CYFUS_RS22080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CYFUS_RS22115	COG0318	PFAM AMP-dependent synthetase and ligase
CYFUS_RS22200	COG0459	protein refolding
CYFUS_RS22205	COG4191	Histidine kinase
CYFUS_RS22210	COG3706	GGDEF domain
CYFUS_RS22225	COG0525	valine-tRNA ligase activity
CYFUS_RS22235	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
CYFUS_RS22240	COG0824	Thioesterase
CYFUS_RS22245	COG1494	fructose-1,6-bisphosphatase
CYFUS_RS22260	COG1397	ADP-ribosylglycohydrolase
CYFUS_RS22265	COG0148	phosphopyruvate hydratase activity
CYFUS_RS22270	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CYFUS_RS22275	COG0739	heme binding
CYFUS_RS22300	COG0577	efflux transmembrane transporter activity
CYFUS_RS22300	COG1136	(ABC) transporter
CYFUS_RS22325	COG1136	(ABC) transporter
CYFUS_RS22330	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CYFUS_RS22335	COG5002	protein histidine kinase activity
CYFUS_RS22405	COG2909	trisaccharide binding
CYFUS_RS22425	COG2198	Histidine kinase
CYFUS_RS22425	COG0643	Histidine kinase
CYFUS_RS22430	COG0840	transmembrane signaling receptor activity
CYFUS_RS22435	COG0840	transmembrane signaling receptor activity
CYFUS_RS22440	COG0835	chemotaxis
CYFUS_RS22445	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CYFUS_RS22455	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CYFUS_RS22470	COG2011	ABC-type metal ion transport system permease component
CYFUS_RS22475	COG1464	Belongs to the NlpA lipoprotein family
CYFUS_RS22495	COG1309	transcriptional regulator
CYFUS_RS22500	COG3507	Belongs to the glycosyl hydrolase 43 family
CYFUS_RS22540	COG0559	Belongs to the binding-protein-dependent transport system permease family
CYFUS_RS22550	COG0583	DNA-binding transcription factor activity
CYFUS_RS22565	COG2271	Major facilitator Superfamily
CYFUS_RS22580	COG2721	sulfolactate sulfo-lyase activity
CYFUS_RS22595	COG0574	Belongs to the PEP-utilizing enzyme family
CYFUS_RS22595	COG3848	Pyruvate phosphate dikinase
CYFUS_RS22625	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CYFUS_RS22705	COG0583	DNA-binding transcription factor activity
CYFUS_RS22750	COG0352	thiamine-phosphate diphosphorylase activity
CYFUS_RS22750	COG0351	phosphomethylpyrimidine kinase
CYFUS_RS22755	COG0617	tRNA 3'-terminal CCA addition
CYFUS_RS22765	COG0482	sulfurtransferase activity
CYFUS_RS22775	COG1482	cell wall glycoprotein biosynthetic process
CYFUS_RS22800	COG0481	GTPase activity
CYFUS_RS22810	COG0540	Belongs to the ATCase OTCase family
CYFUS_RS22820	COG0505	Belongs to the CarA family
CYFUS_RS22835	COG0667	Aldo Keto reductase
CYFUS_RS22845	COG4191	Histidine kinase
CYFUS_RS22850	COG2815	serine threonine protein kinase
CYFUS_RS22850	COG0515	serine threonine protein kinase
CYFUS_RS22865	COG2124	cytochrome p450
CYFUS_RS22865	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CYFUS_RS22890	COG1472	Belongs to the glycosyl hydrolase 3 family
CYFUS_RS22900	COG1012	belongs to the aldehyde dehydrogenase family
CYFUS_RS22910	COG0583	DNA-binding transcription factor activity
CYFUS_RS22950	COG1695	Transcriptional regulator
CYFUS_RS22955	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CYFUS_RS22990	COG0372	Belongs to the citrate synthase family
CYFUS_RS22995	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CYFUS_RS23000	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CYFUS_RS23005	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CYFUS_RS23020	COG2226	methyltransferase
CYFUS_RS23030	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CYFUS_RS23040	COG1575	Belongs to the MenA family. Type 1 subfamily
CYFUS_RS23045	COG4948	Mandelate Racemase Muconate Lactonizing
CYFUS_RS23075	COG0538	isocitrate dehydrogenase activity
CYFUS_RS23085	COG1053	succinate dehydrogenase
CYFUS_RS23090	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CYFUS_RS23095	COG0045	succinate-CoA ligase (ADP-forming) activity
CYFUS_RS23100	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CYFUS_RS23115	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CYFUS_RS23120	COG0228	four-way junction DNA binding
CYFUS_RS23125	COG1837	Belongs to the UPF0109 family
CYFUS_RS23130	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CYFUS_RS23135	COG0336	Belongs to the RNA methyltransferase TrmD family
CYFUS_RS23140	COG0335	large ribosomal subunit rRNA binding
CYFUS_RS23150	COG0792	nuclease activity
CYFUS_RS23155	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CYFUS_RS23170	COG2204	response regulator
CYFUS_RS23180	COG0539	negative regulation of cytoplasmic translation
CYFUS_RS23200	COG0515	serine threonine protein kinase
CYFUS_RS23205	COG2755	lipolytic protein G-D-S-L family
CYFUS_RS23205	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CYFUS_RS23215	COG0460	homoserine dehydrogenase
CYFUS_RS23215	COG0527	aspartate kinase activity
CYFUS_RS23220	COG0626	cystathionine gamma-synthase activity
CYFUS_RS23225	COG0626	cystathionine gamma-synthase activity
CYFUS_RS23230	COG2329	Antibiotic biosynthesis monooxygenase
CYFUS_RS23285	COG0544	peptidyl-prolyl cis-trans isomerase activity
CYFUS_RS23325	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS23340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CYFUS_RS23345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CYFUS_RS23350	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CYFUS_RS23370	COG0667	Aldo Keto reductase
CYFUS_RS23380	COG4585	Histidine kinase
CYFUS_RS23395	COG2205	protein histidine kinase activity
CYFUS_RS23425	COG0523	cobalamin synthesis protein
CYFUS_RS23455	COG2255	four-way junction helicase activity
CYFUS_RS23475	COG1136	(ABC) transporter
CYFUS_RS23480	COG2204	response regulator
CYFUS_RS23485	COG3852	Histidine kinase
CYFUS_RS23515	COG0641	radical SAM
CYFUS_RS23525	COG1136	(ABC) transporter
CYFUS_RS23525	COG0577	efflux transmembrane transporter activity
CYFUS_RS23545	COG4191	Histidine kinase
CYFUS_RS23565	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CYFUS_RS23570	COG1472	Belongs to the glycosyl hydrolase 3 family
CYFUS_RS23575	COG1881	PFAM PEBP family protein
CYFUS_RS23580	COG2304	oxidoreductase activity
CYFUS_RS23600	COG1278	Cold shock
CYFUS_RS23610	COG1309	transcriptional regulator
CYFUS_RS23615	COG3631	Ketosteroid isomerase-related protein
CYFUS_RS23620	COG0702	epimerase
CYFUS_RS23625	COG0545	Peptidyl-prolyl cis-trans isomerase
CYFUS_RS23645	COG0628	permease
CYFUS_RS23660	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CYFUS_RS23670	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CYFUS_RS23675	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CYFUS_RS23680	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CYFUS_RS23685	COG0072	phenylalanine-tRNA ligase activity
CYFUS_RS23690	COG0776	regulation of translation
CYFUS_RS23740	COG0625	glutathione transferase activity
CYFUS_RS23755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CYFUS_RS23760	COG1960	acyl-CoA dehydrogenase activity
CYFUS_RS23765	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CYFUS_RS23795	COG1090	epimerase
CYFUS_RS23800	COG4213	ABC transporter substrate-binding protein
CYFUS_RS23825	COG1280	lysine exporter protein (LysE YggA)
CYFUS_RS23830	COG0784	Response regulator, receiver
CYFUS_RS23830	COG4191	Histidine kinase
CYFUS_RS23835	COG0402	S-adenosylhomocysteine deaminase activity
CYFUS_RS23840	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CYFUS_RS23865	COG0785	Cytochrome C biogenesis protein
CYFUS_RS23890	COG1309	transcriptional regulator
CYFUS_RS23900	COG1764	response to oxidative stress
CYFUS_RS23905	COG1846	Transcriptional regulator
CYFUS_RS23910	COG0733	neurotransmitter:sodium symporter activity
CYFUS_RS23935	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CYFUS_RS23950	COG3401	FG-GAP repeat protein
CYFUS_RS23970	COG4771	TonB-dependent receptor
CYFUS_RS23980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CYFUS_RS24000	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CYFUS_RS24005	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CYFUS_RS24010	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CYFUS_RS24135	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CYFUS_RS24160	COG0860	N-Acetylmuramoyl-L-alanine amidase
CYFUS_RS24165	COG1917	Cupin 2, conserved barrel domain protein
CYFUS_RS24170	COG0583	DNA-binding transcription factor activity
CYFUS_RS24175	COG1063	alcohol dehydrogenase
CYFUS_RS24180	COG4124	Belongs to the glycosyl hydrolase 26 family
CYFUS_RS24210	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CYFUS_RS24230	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CYFUS_RS24230	COG0475	glutathione-regulated potassium exporter activity
CYFUS_RS24235	COG0009	L-threonylcarbamoyladenylate synthase
CYFUS_RS24240	COG4974	Belongs to the 'phage' integrase family
CYFUS_RS24255	COG2130	NADP-dependent
CYFUS_RS24275	COG2130	NADP-dependent
CYFUS_RS24310	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CYFUS_RS24315	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CYFUS_RS24320	COG2080	2 iron, 2 sulfur cluster binding
CYFUS_RS24340	COG1643	Atp-dependent helicase
CYFUS_RS24360	COG1643	Atp-dependent helicase
CYFUS_RS24400	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CYFUS_RS24405	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CYFUS_RS24410	COG1187	pseudouridine synthase activity
CYFUS_RS24450	COG2815	serine threonine protein kinase
CYFUS_RS24450	COG0515	serine threonine protein kinase
CYFUS_RS24485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CYFUS_RS24490	COG0270	DNA (cytosine-5-)-methyltransferase activity
CYFUS_RS24500	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CYFUS_RS24550	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CYFUS_RS24565	COG0430	RNA-3'-phosphate cyclase activity
CYFUS_RS24610	COG5002	protein histidine kinase activity
CYFUS_RS24615	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS24635	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CYFUS_RS24670	COG3940	Belongs to the glycosyl hydrolase 43 family
CYFUS_RS24675	COG3940	Belongs to the glycosyl hydrolase 43 family
CYFUS_RS24685	COG1172	Belongs to the binding-protein-dependent transport system permease family
CYFUS_RS24690	COG1172	Belongs to the binding-protein-dependent transport system permease family
CYFUS_RS24695	COG1129	ABC transporter
CYFUS_RS24700	COG1879	ABC-type sugar transport system periplasmic component
CYFUS_RS24705	COG2160	L-arabinose isomerase activity
CYFUS_RS24710	COG1069	ribulokinase activity
CYFUS_RS24715	COG1609	Transcriptional regulator
CYFUS_RS24725	COG4214	carbohydrate transport
CYFUS_RS24750	COG3940	Belongs to the glycosyl hydrolase 43 family
CYFUS_RS24755	COG1846	Transcriptional regulator
CYFUS_RS24760	COG2329	Antibiotic biosynthesis monooxygenase
CYFUS_RS24780	COG3227	Zinc metalloprotease (Elastase)
CYFUS_RS24785	COG0626	cystathionine gamma-synthase activity
CYFUS_RS24820	COG3209	COG3209 Rhs family protein
CYFUS_RS24850	COG2205	protein histidine kinase activity
CYFUS_RS24890	COG1335	isochorismatase
CYFUS_RS24915	COG0702	epimerase
CYFUS_RS24970	COG2204	response regulator
CYFUS_RS24975	COG5000	phosphorelay sensor kinase activity
CYFUS_RS24980	COG0596	Alpha beta hydrolase
CYFUS_RS24985	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS24990	COG1309	transcriptional regulator
CYFUS_RS25020	COG0559	Belongs to the binding-protein-dependent transport system permease family
CYFUS_RS25035	COG1129	ABC transporter
CYFUS_RS25115	COG0308	aminopeptidase N
CYFUS_RS25125	COG2207	Transcriptional regulator
CYFUS_RS25140	COG3047	cAMP biosynthetic process
CYFUS_RS25140	COG2885	chlorophyll binding
CYFUS_RS25150	COG4221	oxidoreductase activity
CYFUS_RS25160	COG0318	PFAM AMP-dependent synthetase and ligase
CYFUS_RS25165	COG0300	oxidoreductase activity
CYFUS_RS25190	COG1215	transferase activity, transferring glycosyl groups
CYFUS_RS25215	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS25220	COG2205	protein histidine kinase activity
CYFUS_RS25235	COG0840	transmembrane signaling receptor activity
CYFUS_RS25285	COG2832	Protein of unknown function (DUF454)
CYFUS_RS25290	COG0454	-acetyltransferase
CYFUS_RS25295	COG0596	Alpha beta hydrolase
CYFUS_RS25345	COG0583	DNA-binding transcription factor activity
CYFUS_RS25380	COG0583	DNA-binding transcription factor activity
CYFUS_RS25460	COG1858	cytochrome C peroxidase
CYFUS_RS25485	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CYFUS_RS25490	COG1131	(ABC) transporter
CYFUS_RS25510	COG0616	signal peptide processing
CYFUS_RS25520	COG0601	transmembrane transport
CYFUS_RS25525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CYFUS_RS25530	COG0444	Belongs to the ABC transporter superfamily
CYFUS_RS25535	COG4608	Belongs to the ABC transporter superfamily
CYFUS_RS25540	COG2723	6-phospho-beta-galactosidase activity
CYFUS_RS25555	COG0489	protein tyrosine kinase activity
CYFUS_RS25570	COG1250	3-hydroxyacyl-CoA dehydrogenase
CYFUS_RS25575	COG1024	Enoyl-CoA hydratase
CYFUS_RS25580	COG1960	acyl-CoA dehydrogenase activity
CYFUS_RS25590	COG1960	acyl-CoA dehydrogenase activity
CYFUS_RS25600	COG1309	transcriptional regulator
CYFUS_RS25610	COG0183	Belongs to the thiolase family
CYFUS_RS25615	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CYFUS_RS25620	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CYFUS_RS25625	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CYFUS_RS25650	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CYFUS_RS25655	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CYFUS_RS25665	COG0586	Pfam SNARE associated Golgi protein
CYFUS_RS25675	COG0519	Catalyzes the synthesis of GMP from XMP
CYFUS_RS25675	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CYFUS_RS25690	COG2815	serine threonine protein kinase
CYFUS_RS25690	COG0515	serine threonine protein kinase
CYFUS_RS25700	COG0494	nUDIX hydrolase
CYFUS_RS25715	COG1160	GTP binding
CYFUS_RS25720	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CYFUS_RS25725	COG0571	ribonuclease III activity
CYFUS_RS25730	COG1960	acyl-CoA dehydrogenase activity
CYFUS_RS25735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CYFUS_RS25750	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CYFUS_RS25770	COG2234	aminopeptidase activity
CYFUS_RS25780	COG3942	CHAP domain
CYFUS_RS25780	COG1388	LysM domain
CYFUS_RS25785	COG2226	methyltransferase
CYFUS_RS25790	COG1024	Enoyl-CoA hydratase
CYFUS_RS25805	COG2814	Major facilitator Superfamily
CYFUS_RS25845	COG0300	oxidoreductase activity
CYFUS_RS25850	COG0840	transmembrane signaling receptor activity
CYFUS_RS25870	COG0501	Belongs to the peptidase M48B family
CYFUS_RS25895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CYFUS_RS25905	COG1309	transcriptional regulator
CYFUS_RS25920	COG1902	pentaerythritol trinitrate reductase activity
CYFUS_RS25935	COG1703	isobutyryl-CoA mutase activity
CYFUS_RS25935	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CYFUS_RS25935	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CYFUS_RS25940	COG1703	isobutyryl-CoA mutase activity
CYFUS_RS25950	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CYFUS_RS25950	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CYFUS_RS25990	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CYFUS_RS26015	COG0156	8-amino-7-oxononanoate synthase activity
CYFUS_RS26020	COG0456	acetyltransferase
CYFUS_RS26035	COG1830	Aldolase
CYFUS_RS26040	COG0142	geranyltranstransferase activity
CYFUS_RS26060	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CYFUS_RS26060	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CYFUS_RS26065	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS26085	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS26090	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CYFUS_RS26100	COG0688	phosphatidylethanolamine metabolic process
CYFUS_RS26110	COG0514	ATP-dependent DNA helicase (RecQ)
CYFUS_RS26110	COG0514	ATP-dependent DNA helicase (RecQ)
CYFUS_RS26130	COG0644	oxidoreductase
CYFUS_RS26170	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CYFUS_RS26175	COG1127	ABC transporter
CYFUS_RS26180	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CYFUS_RS26200	COG0517	IMP dehydrogenase activity
CYFUS_RS26200	COG1994	Peptidase M50
CYFUS_RS26205	COG0564	pseudouridine synthase activity
CYFUS_RS26215	COG0612	Peptidase, M16
CYFUS_RS26220	COG2124	cytochrome p450
CYFUS_RS26240	COG0667	Aldo Keto reductase
CYFUS_RS26255	COG0583	DNA-binding transcription factor activity
CYFUS_RS26295	COG2124	cytochrome p450
CYFUS_RS26340	COG2124	cytochrome p450
CYFUS_RS26345	COG2197	response regulator
CYFUS_RS26390	COG2521	methyltransferase
CYFUS_RS26390	COG2136	Putative SAM-dependent methyltransferase
CYFUS_RS26395	COG2080	2 iron, 2 sulfur cluster binding
CYFUS_RS26400	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CYFUS_RS26405	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CYFUS_RS26485	COG0366	Alpha amylase catalytic
CYFUS_RS26490	COG0366	Alpha amylase catalytic
CYFUS_RS26495	COG3281	Trehalose synthase
CYFUS_RS26500	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CYFUS_RS26555	COG0515	serine threonine protein kinase
CYFUS_RS26555	COG2815	serine threonine protein kinase
CYFUS_RS26560	COG5002	protein histidine kinase activity
CYFUS_RS26565	COG2182	Extracellular solute-binding protein
CYFUS_RS26600	COG0025	NhaP-type Na H and K H
CYFUS_RS26645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CYFUS_RS26650	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CYFUS_RS26655	COG1309	transcriptional regulator
CYFUS_RS26660	COG0604	alcohol dehydrogenase
CYFUS_RS26665	COG3023	N-Acetylmuramoyl-L-alanine amidase
CYFUS_RS26675	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CYFUS_RS26745	COG4977	sequence-specific DNA binding
CYFUS_RS26750	COG2124	cytochrome p450
CYFUS_RS26755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CYFUS_RS26760	COG0583	DNA-binding transcription factor activity
CYFUS_RS26945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CYFUS_RS26955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CYFUS_RS26970	COG1946	Acyl-CoA thioesterase
CYFUS_RS26980	COG4104	PAAR repeat-containing protein
CYFUS_RS26985	COG0625	glutathione transferase activity
CYFUS_RS26990	COG1228	amidohydrolase
CYFUS_RS27035	COG2072	flavoprotein involved in K transport
CYFUS_RS27085	COG2132	Multicopper oxidase
CYFUS_RS27095	COG0583	DNA-binding transcription factor activity
CYFUS_RS27130	COG0840	transmembrane signaling receptor activity
CYFUS_RS27225	COG2815	serine threonine protein kinase
CYFUS_RS27225	COG0515	serine threonine protein kinase
CYFUS_RS27240	COG0585	pseudouridine synthase activity
CYFUS_RS27245	COG1595	DNA-templated transcription, initiation
CYFUS_RS27260	COG0493	'glutamate synthase
CYFUS_RS27265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CYFUS_RS27275	COG4249	Peptidase C14 caspase catalytic subunit p20
CYFUS_RS27275	COG2319	Wd-40 repeat
CYFUS_RS27295	COG2267	carboxylic ester hydrolase activity
CYFUS_RS27320	COG1268	BioY protein
CYFUS_RS27325	COG2124	cytochrome p450
CYFUS_RS27340	COG2133	pyrroloquinoline quinone binding
CYFUS_RS27350	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CYFUS_RS27370	COG0702	epimerase
CYFUS_RS27390	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS27395	COG0583	DNA-binding transcription factor activity
CYFUS_RS27415	COG4221	oxidoreductase activity
CYFUS_RS27435	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CYFUS_RS27440	COG0204	Acyl-transferase
CYFUS_RS27440	COG0318	PFAM AMP-dependent synthetase and ligase
CYFUS_RS27445	COG0708	Exodeoxyribonuclease III
CYFUS_RS27450	COG0596	Alpha beta hydrolase
CYFUS_RS27455	COG0667	Aldo Keto reductase
CYFUS_RS27470	COG3852	Histidine kinase
CYFUS_RS27500	COG1960	acyl-CoA dehydrogenase activity
CYFUS_RS27570	COG0515	serine threonine protein kinase
CYFUS_RS27595	COG0596	Alpha beta hydrolase
CYFUS_RS27600	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS27605	COG4702	Belongs to the UPF0303 family
CYFUS_RS27610	COG2032	superoxide dismutase activity
CYFUS_RS27615	COG0488	(ABC) transporter
CYFUS_RS27630	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CYFUS_RS27645	COG2124	cytochrome p450
CYFUS_RS27650	COG0318	PFAM AMP-dependent synthetase and ligase
CYFUS_RS27665	COG1132	(ABC) transporter
CYFUS_RS27670	COG1132	(ABC) transporter
CYFUS_RS27680	COG0535	radical SAM domain protein
CYFUS_RS27690	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CYFUS_RS27705	COG0667	Aldo Keto reductase
CYFUS_RS27730	COG3290	protein histidine kinase activity
CYFUS_RS27760	COG0625	glutathione transferase activity
CYFUS_RS27780	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CYFUS_RS27825	COG0463	Glycosyl transferase, family 2
CYFUS_RS27925	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CYFUS_RS27945	COG0515	serine threonine protein kinase
CYFUS_RS27990	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CYFUS_RS27995	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CYFUS_RS28000	COG1438	arginine binding
CYFUS_RS28005	COG0165	Argininosuccinate lyase
CYFUS_RS28010	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CYFUS_RS28025	COG1228	amidohydrolase
CYFUS_RS28030	COG3344	reverse transcriptase
CYFUS_RS28100	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CYFUS_RS28110	COG1335	isochorismatase
CYFUS_RS28125	COG1874	Beta-galactosidase
CYFUS_RS28125	COG0366	Alpha amylase catalytic
CYFUS_RS28130	COG2027	D-alanyl-D-alanine carboxypeptidase
CYFUS_RS28175	COG2207	Transcriptional regulator
CYFUS_RS28180	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS28185	COG5002	protein histidine kinase activity
CYFUS_RS28195	COG2198	Histidine kinase
CYFUS_RS28195	COG0784	Response regulator, receiver
CYFUS_RS28195	COG2205	protein histidine kinase activity
CYFUS_RS28205	COG3590	peptidase
CYFUS_RS28210	COG0367	asparagine synthase
CYFUS_RS28215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CYFUS_RS28220	COG1960	acyl-CoA dehydrogenase activity
CYFUS_RS28235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CYFUS_RS28250	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CYFUS_RS28265	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CYFUS_RS28270	COG0742	ribosomal rna small subunit methyltransferase
CYFUS_RS28295	COG0574	Belongs to the PEP-utilizing enzyme family
CYFUS_RS28295	COG3848	Pyruvate phosphate dikinase
CYFUS_RS28315	COG4213	ABC transporter substrate-binding protein
CYFUS_RS28325	COG4214	carbohydrate transport
CYFUS_RS28345	COG1217	gtp-binding protein TYPA
CYFUS_RS28355	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CYFUS_RS28370	COG2354	Protein conserved in bacteria
CYFUS_RS28380	COG3781	membrane
CYFUS_RS28385	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CYFUS_RS28430	COG0598	Magnesium transport protein CorA
CYFUS_RS28435	COG2267	carboxylic ester hydrolase activity
CYFUS_RS28525	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CYFUS_RS28535	COG0438	transferase activity, transferring glycosyl groups
CYFUS_RS28560	COG4133	protoheme IX ABC transporter activity
CYFUS_RS28580	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CYFUS_RS28585	COG1138	Cytochrome C-type biogenesis protein
CYFUS_RS28635	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CYFUS_RS28640	COG1228	amidohydrolase
CYFUS_RS28655	COG0802	atpase or kinase
CYFUS_RS28660	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CYFUS_RS28660	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CYFUS_RS28665	COG0736	holo-[acyl-carrier-protein] synthase activity
CYFUS_RS28670	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CYFUS_RS28675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CYFUS_RS28680	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CYFUS_RS28685	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CYFUS_RS28690	COG0037	tRNA processing
CYFUS_RS28720	COG1671	Belongs to the UPF0178 family
CYFUS_RS28725	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CYFUS_RS28730	COG0784	Response regulator, receiver
CYFUS_RS28730	COG4191	Histidine kinase
CYFUS_RS28770	COG2226	methyltransferase
CYFUS_RS28805	COG4251	negative regulation of phosphorylation
CYFUS_RS28810	COG0784	Response regulator, receiver
CYFUS_RS28815	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS28830	COG1573	uracil-dna glycosylase
CYFUS_RS28845	COG0667	Aldo Keto reductase
CYFUS_RS28855	COG4282	regulation of fungal-type cell wall biogenesis
CYFUS_RS28875	COG3227	Zinc metalloprotease (Elastase)
CYFUS_RS28885	COG3507	Belongs to the glycosyl hydrolase 43 family
CYFUS_RS28920	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CYFUS_RS28935	COG0753	catalase activity
CYFUS_RS28965	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS28970	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CYFUS_RS28980	COG0501	Belongs to the peptidase M48B family
CYFUS_RS28990	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CYFUS_RS29000	COG0631	protein serine/threonine phosphatase activity
CYFUS_RS29025	COG1218	3'(2'),5'-bisphosphate nucleotidase
CYFUS_RS29085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CYFUS_RS29095	COG2814	Major facilitator Superfamily
CYFUS_RS29115	COG1653	transport
CYFUS_RS29125	COG1309	transcriptional regulator
CYFUS_RS29190	COG0515	serine threonine protein kinase
CYFUS_RS29205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CYFUS_RS29220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CYFUS_RS29235	COG0076	glutamate decarboxylase activity
CYFUS_RS29255	COG3781	membrane
CYFUS_RS29280	COG2119	membrane
CYFUS_RS29290	COG1131	(ABC) transporter
CYFUS_RS29350	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CYFUS_RS29355	COG2239	Acts as a magnesium transporter
CYFUS_RS29360	COG4221	oxidoreductase activity
CYFUS_RS29360	COG3321	synthase
CYFUS_RS29360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CYFUS_RS29360	COG0604	alcohol dehydrogenase
CYFUS_RS29370	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CYFUS_RS29375	COG0010	Belongs to the arginase family
CYFUS_RS29380	COG3537	Alpha-1,2-mannosidase
CYFUS_RS29390	COG0515	serine threonine protein kinase
CYFUS_RS29425	COG0583	DNA-binding transcription factor activity
CYFUS_RS29485	COG3227	Zinc metalloprotease (Elastase)
CYFUS_RS29500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CYFUS_RS29530	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CYFUS_RS29530	COG0678	peroxiredoxin activity
CYFUS_RS29540	COG3034	peptidoglycan biosynthetic process
CYFUS_RS29575	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS29580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CYFUS_RS29585	COG0515	serine threonine protein kinase
CYFUS_RS29600	COG1215	transferase activity, transferring glycosyl groups
CYFUS_RS29660	COG0443	Heat shock 70 kDa protein
CYFUS_RS29680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CYFUS_RS29700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CYFUS_RS29705	COG0644	oxidoreductase
CYFUS_RS29750	COG1132	(ABC) transporter
CYFUS_RS29765	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CYFUS_RS29825	COG1064	alcohol dehydrogenase
CYFUS_RS29835	COG2080	2 iron, 2 sulfur cluster binding
CYFUS_RS29840	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CYFUS_RS29840	COG2010	Cytochrome c
CYFUS_RS29880	COG0006	proline dipeptidase activity
CYFUS_RS29920	COG0515	serine threonine protein kinase
CYFUS_RS29930	COG0022	dehydrogenase e1 component
CYFUS_RS29950	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CYFUS_RS30015	COG3604	Transcriptional regulator
CYFUS_RS30020	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CYFUS_RS30025	COG3284	Transcriptional regulator
CYFUS_RS30030	COG1012	belongs to the aldehyde dehydrogenase family
CYFUS_RS30060	COG0003	Pfam Anion-transporting ATPase
CYFUS_RS30085	COG3321	synthase
CYFUS_RS30085	COG0604	alcohol dehydrogenase
CYFUS_RS30100	COG1960	acyl-CoA dehydrogenase activity
CYFUS_RS30105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CYFUS_RS30120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CYFUS_RS30135	COG1309	transcriptional regulator
CYFUS_RS30140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CYFUS_RS30145	COG0765	amino acid transport
CYFUS_RS30150	COG0765	amino acid transport
CYFUS_RS30160	COG2366	antibiotic biosynthetic process
CYFUS_RS30210	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CYFUS_RS30215	COG2207	Transcriptional regulator
CYFUS_RS30220	COG1335	isochorismatase
CYFUS_RS30245	COG0515	serine threonine protein kinase
CYFUS_RS30260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CYFUS_RS30260	COG4191	Histidine kinase
CYFUS_RS30325	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CYFUS_RS30325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CYFUS_RS30330	COG0343	queuine tRNA-ribosyltransferase activity
CYFUS_RS30335	COG1309	transcriptional regulator
CYFUS_RS30340	COG2124	cytochrome p450
CYFUS_RS30345	COG2124	cytochrome p450
CYFUS_RS30350	COG2124	cytochrome p450
CYFUS_RS30355	COG2124	cytochrome p450
CYFUS_RS30360	COG0488	(ABC) transporter
CYFUS_RS30365	COG1295	ribonuclease BN
CYFUS_RS30450	COG1196	nuclear chromosome segregation
CYFUS_RS30450	COG0739	heme binding
CYFUS_RS30450	COG0741	lytic transglycosylase activity
CYFUS_RS30470	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CYFUS_RS30510	COG4191	Histidine kinase
CYFUS_RS30510	COG2205	protein histidine kinase activity
CYFUS_RS30510	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS30515	COG2205	protein histidine kinase activity
CYFUS_RS30535	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CYFUS_RS30540	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CYFUS_RS30635	COG4608	Belongs to the ABC transporter superfamily
CYFUS_RS30670	COG1960	acyl-CoA dehydrogenase activity
CYFUS_RS30680	COG2030	dehydratase
CYFUS_RS30695	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CYFUS_RS30705	COG0714	Associated with various cellular activities
CYFUS_RS30740	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CYFUS_RS30750	COG1193	negative regulation of DNA recombination
CYFUS_RS30770	COG0024	Methionine aminopeptidase
CYFUS_RS30785	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS30790	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CYFUS_RS30795	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CYFUS_RS30800	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CYFUS_RS30805	COG0529	Catalyzes the synthesis of activated sulfate
CYFUS_RS30810	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CYFUS_RS30840	COG2267	carboxylic ester hydrolase activity
CYFUS_RS30850	COG4566	intracellular signal transduction
CYFUS_RS30855	COG4566	intracellular signal transduction
CYFUS_RS30865	COG2205	protein histidine kinase activity
CYFUS_RS30865	COG0784	Response regulator, receiver
CYFUS_RS30915	COG1597	lipid kinase activity
CYFUS_RS30920	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CYFUS_RS30950	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CYFUS_RS30950	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CYFUS_RS30955	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CYFUS_RS30960	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CYFUS_RS30965	COG1862	Preprotein translocase
CYFUS_RS30980	COG2385	sporulation resulting in formation of a cellular spore
CYFUS_RS30995	COG2814	Major facilitator Superfamily
CYFUS_RS31000	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CYFUS_RS31025	COG0515	serine threonine protein kinase
CYFUS_RS31070	COG3290	protein histidine kinase activity
CYFUS_RS31080	COG0436	Aminotransferase
CYFUS_RS31090	COG3852	Histidine kinase
CYFUS_RS31095	COG1122	ATPase activity
CYFUS_RS31100	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CYFUS_RS31105	COG1268	BioY protein
CYFUS_RS31110	COG1335	isochorismatase
CYFUS_RS31115	COG3227	Zinc metalloprotease (Elastase)
CYFUS_RS31135	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CYFUS_RS31140	COG1012	belongs to the aldehyde dehydrogenase family
CYFUS_RS31155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CYFUS_RS31165	COG3615	Tellurite resistance protein tehB
CYFUS_RS31165	COG0500	methyltransferase
CYFUS_RS31170	COG0517	IMP dehydrogenase activity
CYFUS_RS31170	COG0516	GMP reductase activity
CYFUS_RS31175	COG0402	S-adenosylhomocysteine deaminase activity
CYFUS_RS31180	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS31185	COG1309	transcriptional regulator
CYFUS_RS31190	COG2137	regulation of response to DNA damage stimulus
CYFUS_RS31215	COG2124	cytochrome p450
CYFUS_RS31260	COG2304	oxidoreductase activity
CYFUS_RS31295	COG0583	DNA-binding transcription factor activity
CYFUS_RS31300	COG0625	glutathione transferase activity
CYFUS_RS31315	COG0442	prolyl-tRNA aminoacylation
CYFUS_RS31320	COG0564	pseudouridine synthase activity
CYFUS_RS31325	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CYFUS_RS31330	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CYFUS_RS31335	COG2895	sulfate adenylyltransferase (ATP) activity
CYFUS_RS31335	COG0529	Catalyzes the synthesis of activated sulfate
CYFUS_RS31340	COG0175	sulfate reduction
CYFUS_RS31345	COG1648	precorrin-2 dehydrogenase activity
CYFUS_RS31345	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CYFUS_RS31355	COG0175	sulfate reduction
CYFUS_RS31360	COG0633	Ferredoxin
CYFUS_RS31360	COG3217	Mosc domain protein beta barrel domain protein
CYFUS_RS31365	COG1295	ribonuclease BN
CYFUS_RS31365	COG1959	2 iron, 2 sulfur cluster binding
CYFUS_RS31420	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CYFUS_RS31440	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CYFUS_RS31445	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CYFUS_RS31450	COG1492	cobalamin metabolic process
CYFUS_RS31455	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CYFUS_RS31460	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CYFUS_RS31480	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CYFUS_RS31540	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
CYFUS_RS31545	COG1122	ATPase activity
CYFUS_RS31560	COG0310	cobalt ion transport
CYFUS_RS31565	COG0778	Nitroreductase
CYFUS_RS31570	COG0406	alpha-ribazole phosphatase activity
CYFUS_RS31575	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CYFUS_RS31585	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS31585	COG0604	alcohol dehydrogenase
CYFUS_RS31585	COG3321	synthase
CYFUS_RS31615	COG0339	signal peptide processing
CYFUS_RS31620	COG2205	protein histidine kinase activity
CYFUS_RS31625	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS31645	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CYFUS_RS31655	COG2197	response regulator
CYFUS_RS31670	COG0484	heat shock protein binding
CYFUS_RS31675	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CYFUS_RS31710	COG1450	Type ii and iii secretion system protein
CYFUS_RS31735	COG0751	glycine-tRNA ligase activity
CYFUS_RS31740	COG0752	glycyl-tRNA synthetase alpha subunit
CYFUS_RS31750	COG1381	Involved in DNA repair and RecF pathway recombination
CYFUS_RS31785	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CYFUS_RS31790	COG0085	RNA polymerase activity
CYFUS_RS31795	COG0222	ribosome binding
CYFUS_RS31800	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CYFUS_RS31805	COG0081	regulation of translation
CYFUS_RS31810	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CYFUS_RS31830	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CYFUS_RS31835	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CYFUS_RS31860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CYFUS_RS31870	COG0189	ligase activity
CYFUS_RS31895	COG1643	Atp-dependent helicase
CYFUS_RS31935	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CYFUS_RS31935	COG0047	phosphoribosylformylglycinamidine synthase activity
CYFUS_RS31940	COG0243	molybdopterin cofactor binding
CYFUS_RS31950	COG2385	sporulation resulting in formation of a cellular spore
CYFUS_RS31950	COG2247	cell wall binding repeat
CYFUS_RS31970	COG2226	methyltransferase
CYFUS_RS31980	COG0646	methionine synthase
CYFUS_RS31980	COG1410	methionine synthase
CYFUS_RS31985	COG4191	Histidine kinase
CYFUS_RS31990	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CYFUS_RS31990	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CYFUS_RS31995	COG0509	glycine decarboxylation via glycine cleavage system
CYFUS_RS32005	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CYFUS_RS32025	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CYFUS_RS32030	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CYFUS_RS32035	COG2205	protein histidine kinase activity
CYFUS_RS32045	COG0318	PFAM AMP-dependent synthetase and ligase
CYFUS_RS32045	COG0300	oxidoreductase activity
CYFUS_RS32045	COG3321	synthase
CYFUS_RS32045	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS32045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CYFUS_RS32050	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CYFUS_RS32110	COG5002	protein histidine kinase activity
CYFUS_RS32160	COG0318	PFAM AMP-dependent synthetase and ligase
CYFUS_RS32165	COG1914	H( )-stimulated, divalent metal cation uptake system
CYFUS_RS32170	COG0667	Aldo Keto reductase
CYFUS_RS32210	COG0515	serine threonine protein kinase
CYFUS_RS32230	COG1181	Belongs to the D-alanine--D-alanine ligase family
CYFUS_RS32240	COG0501	Belongs to the peptidase M48B family
CYFUS_RS32265	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CYFUS_RS32270	COG2011	ABC-type metal ion transport system permease component
CYFUS_RS32275	COG1464	Belongs to the NlpA lipoprotein family
CYFUS_RS32295	COG2840	Smr protein MutS2
CYFUS_RS32305	COG0167	dihydroorotate dehydrogenase activity
CYFUS_RS32330	COG3383	formate dehydrogenase (NAD+) activity
CYFUS_RS32340	COG2205	protein histidine kinase activity
CYFUS_RS32345	COG2132	Multicopper oxidase
CYFUS_RS32360	COG3052	prosthetic group binding
CYFUS_RS32415	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CYFUS_RS32425	COG0583	DNA-binding transcription factor activity
CYFUS_RS32440	COG1830	Aldolase
CYFUS_RS32455	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CYFUS_RS32470	COG1764	response to oxidative stress
CYFUS_RS32475	COG0596	Alpha beta hydrolase
CYFUS_RS32490	COG2267	carboxylic ester hydrolase activity
CYFUS_RS32500	COG2124	cytochrome p450
CYFUS_RS32505	COG4221	oxidoreductase activity
CYFUS_RS32545	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CYFUS_RS32560	COG0237	dephospho-CoA kinase activity
CYFUS_RS32575	COG1253	flavin adenine dinucleotide binding
CYFUS_RS32590	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CYFUS_RS32595	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CYFUS_RS32630	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CYFUS_RS32640	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CYFUS_RS32660	COG1496	oxidoreductase activity
CYFUS_RS32670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CYFUS_RS32675	COG1543	Belongs to the glycosyl hydrolase 57 family
CYFUS_RS32690	COG1196	nuclear chromosome segregation
CYFUS_RS32690	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS32700	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CYFUS_RS32720	COG1227	inorganic diphosphatase activity
CYFUS_RS32725	COG1104	cysteine desulfurase activity
CYFUS_RS32730	COG0515	serine threonine protein kinase
CYFUS_RS32750	COG1692	metallophosphoesterase
CYFUS_RS32765	COG0515	serine threonine protein kinase
CYFUS_RS32765	COG2815	serine threonine protein kinase
CYFUS_RS32770	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CYFUS_RS32780	COG2135	peptidase activity
CYFUS_RS32795	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CYFUS_RS32810	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CYFUS_RS32810	COG3608	succinylglutamate desuccinylase aspartoacylase
CYFUS_RS32835	COG3858	chitin binding
CYFUS_RS32860	COG0835	chemotaxis
CYFUS_RS32865	COG0840	transmembrane signaling receptor activity
CYFUS_RS32870	COG2815	serine threonine protein kinase
CYFUS_RS32870	COG0515	serine threonine protein kinase
CYFUS_RS32875	COG1505	serine-type exopeptidase activity
CYFUS_RS32900	COG4771	TonB-dependent receptor
CYFUS_RS32975	COG1960	acyl-CoA dehydrogenase activity
CYFUS_RS33030	COG1846	Transcriptional regulator
CYFUS_RS33035	COG1764	response to oxidative stress
CYFUS_RS33070	COG3321	synthase
CYFUS_RS33070	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS33070	COG0604	alcohol dehydrogenase
CYFUS_RS33075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CYFUS_RS33085	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS33095	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CYFUS_RS33110	COG0277	FAD linked oxidase domain protein
CYFUS_RS33115	COG0302	gtp cyclohydrolase
CYFUS_RS33125	COG3746	phosphate-selective porin O and P
CYFUS_RS33140	COG1121	(ABC) transporter
CYFUS_RS33145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CYFUS_RS33195	COG0670	Belongs to the BI1 family
CYFUS_RS33205	COG3411	Ferredoxin
CYFUS_RS33210	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CYFUS_RS33225	COG0165	Argininosuccinate lyase
CYFUS_RS33235	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CYFUS_RS33280	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CYFUS_RS33290	COG0582	viral genome integration into host DNA
CYFUS_RS33500	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CYFUS_RS33585	COG1129	ABC transporter
CYFUS_RS33585	COG0842	Transport permease protein
CYFUS_RS33615	COG1595	DNA-templated transcription, initiation
CYFUS_RS33635	COG0477	Major facilitator Superfamily
CYFUS_RS33640	COG1758	RNA polymerase activity
CYFUS_RS33660	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CYFUS_RS33665	COG0459	protein refolding
CYFUS_RS33680	COG3829	transcription factor binding
CYFUS_RS33690	COG1196	nuclear chromosome segregation
CYFUS_RS33695	COG1253	flavin adenine dinucleotide binding
CYFUS_RS33705	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CYFUS_RS33710	COG2890	protein-(glutamine-N5) methyltransferase activity
CYFUS_RS33715	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CYFUS_RS33740	COG3590	peptidase
CYFUS_RS33750	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CYFUS_RS33760	COG3220	belongs to the UPF0276 family
CYFUS_RS33770	COG3800	Transcriptional regulator
CYFUS_RS33770	COG1396	sequence-specific DNA binding
CYFUS_RS33790	COG0515	serine threonine protein kinase
CYFUS_RS33840	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CYFUS_RS33845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CYFUS_RS33850	COG0765	amino acid transport
CYFUS_RS33855	COG1126	abc transporter atp-binding protein
CYFUS_RS33870	COG0544	peptidyl-prolyl cis-trans isomerase activity
CYFUS_RS33885	COG0583	DNA-binding transcription factor activity
CYFUS_RS33925	COG0440	acetolactate synthase activity
CYFUS_RS33930	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CYFUS_RS33935	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CYFUS_RS33940	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CYFUS_RS33950	COG0473	3-isopropylmalate dehydrogenase activity
CYFUS_RS33955	COG0129	dihydroxy-acid dehydratase activity
CYFUS_RS33960	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CYFUS_RS33965	COG0582	viral genome integration into host DNA
CYFUS_RS33990	COG2815	serine threonine protein kinase
CYFUS_RS33990	COG0515	serine threonine protein kinase
CYFUS_RS34015	COG4974	Belongs to the 'phage' integrase family
CYFUS_RS34045	COG1132	(ABC) transporter
CYFUS_RS34065	COG3693	PFAM glycoside hydrolase, family 10
CYFUS_RS34065	COG3509	depolymerase
CYFUS_RS34075	COG4191	Histidine kinase
CYFUS_RS34080	COG2815	serine threonine protein kinase
CYFUS_RS34080	COG0515	serine threonine protein kinase
CYFUS_RS34085	COG4566	intracellular signal transduction
CYFUS_RS34090	COG0513	Belongs to the DEAD box helicase family
CYFUS_RS34115	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CYFUS_RS34130	COG0490	domain, Protein
CYFUS_RS34130	COG0471	metal ion transport
CYFUS_RS34140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CYFUS_RS34170	COG1742	UPF0060 membrane protein
CYFUS_RS34180	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS34220	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS34235	COG0730	response to heat
CYFUS_RS34245	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CYFUS_RS34265	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CYFUS_RS34265	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CYFUS_RS34270	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CYFUS_RS34280	COG2255	four-way junction helicase activity
CYFUS_RS34295	COG0632	four-way junction helicase activity
CYFUS_RS34300	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CYFUS_RS34305	COG0217	transcriptional regulatory protein
CYFUS_RS34345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CYFUS_RS34355	COG0179	Fumarylacetoacetate (FAA) hydrolase
CYFUS_RS34365	COG0430	RNA-3'-phosphate cyclase activity
CYFUS_RS34370	COG1690	Belongs to the RtcB family
CYFUS_RS34375	COG4650	regulator
CYFUS_RS34490	COG1793	dna ligase
CYFUS_RS34565	COG1104	cysteine desulfurase activity
CYFUS_RS34570	COG0822	iron-sulfur transferase activity
CYFUS_RS34575	COG0316	Belongs to the HesB IscA family
CYFUS_RS34580	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CYFUS_RS34590	COG0633	Ferredoxin
CYFUS_RS34690	COG0667	Aldo Keto reductase
CYFUS_RS34695	COG2207	Transcriptional regulator
CYFUS_RS34705	COG1228	amidohydrolase
CYFUS_RS34760	COG1304	FMN binding
CYFUS_RS34765	COG0501	Belongs to the peptidase M48B family
CYFUS_RS34785	COG5002	protein histidine kinase activity
CYFUS_RS34790	COG0612	Peptidase, M16
CYFUS_RS34815	COG2204	response regulator
CYFUS_RS34820	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CYFUS_RS34840	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CYFUS_RS34845	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CYFUS_RS34860	COG2088	sporulation resulting in formation of a cellular spore
CYFUS_RS34865	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CYFUS_RS34870	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CYFUS_RS34875	COG0193	aminoacyl-tRNA hydrolase activity
CYFUS_RS34880	COG0360	Binds together with S18 to 16S ribosomal RNA
CYFUS_RS34885	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CYFUS_RS34890	COG0359	binds to the 23S rRNA
CYFUS_RS34905	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CYFUS_RS34930	COG0542	response to heat
CYFUS_RS34950	COG1172	Belongs to the binding-protein-dependent transport system permease family
CYFUS_RS34955	COG1172	Belongs to the binding-protein-dependent transport system permease family
CYFUS_RS34960	COG1129	ABC transporter
CYFUS_RS34965	COG1879	ABC-type sugar transport system periplasmic component
CYFUS_RS34970	COG3507	Belongs to the glycosyl hydrolase 43 family
CYFUS_RS34975	COG3507	Belongs to the glycosyl hydrolase 43 family
CYFUS_RS34980	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CYFUS_RS34995	COG4771	TonB-dependent receptor
CYFUS_RS35020	COG1396	sequence-specific DNA binding
CYFUS_RS35045	COG0515	serine threonine protein kinase
CYFUS_RS35090	COG3852	Histidine kinase
CYFUS_RS35095	COG2204	response regulator
CYFUS_RS35100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CYFUS_RS35130	COG1289	transmembrane transporter activity
CYFUS_RS35150	COG2205	protein histidine kinase activity
CYFUS_RS35150	COG0784	Response regulator, receiver
CYFUS_RS35195	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CYFUS_RS35195	COG2755	lipolytic protein G-D-S-L family
CYFUS_RS35200	COG2124	cytochrome p450
CYFUS_RS35230	COG0183	Belongs to the thiolase family
CYFUS_RS35235	COG1024	Enoyl-CoA hydratase
CYFUS_RS35235	COG1250	3-hydroxyacyl-CoA dehydrogenase
CYFUS_RS35240	COG0308	aminopeptidase N
CYFUS_RS35260	COG2205	protein histidine kinase activity
CYFUS_RS35275	COG0653	protein targeting
CYFUS_RS35315	COG0693	protein deglycase activity
CYFUS_RS35315	COG0753	catalase activity
CYFUS_RS35340	COG0784	Response regulator, receiver
CYFUS_RS35340	COG4191	Histidine kinase
CYFUS_RS35345	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CYFUS_RS35365	COG0714	Associated with various cellular activities
CYFUS_RS35375	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CYFUS_RS35390	COG1129	ABC transporter
CYFUS_RS35395	COG4603	Belongs to the binding-protein-dependent transport system permease family
CYFUS_RS35400	COG1079	Belongs to the binding-protein-dependent transport system permease family
CYFUS_RS35405	COG1744	ABC transporter substrate-binding protein PnrA-like
CYFUS_RS35430	COG0254	rRNA binding
CYFUS_RS35445	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CYFUS_RS35450	COG2201	protein-glutamate methylesterase activity
CYFUS_RS35480	COG2885	chlorophyll binding
CYFUS_RS35485	COG2204	response regulator
CYFUS_RS35495	COG2259	Doxx family
CYFUS_RS35525	COG0708	Exodeoxyribonuclease III
CYFUS_RS35550	COG5000	phosphorelay sensor kinase activity
CYFUS_RS35570	COG0513	Belongs to the DEAD box helicase family
CYFUS_RS35635	COG1546	Belongs to the CinA family
CYFUS_RS35635	COG1058	Belongs to the CinA family
CYFUS_RS35675	COG2885	chlorophyll binding
CYFUS_RS35675	COG3047	cAMP biosynthetic process
CYFUS_RS35690	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CYFUS_RS35690	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CYFUS_RS35695	COG0252	asparaginase activity
CYFUS_RS35720	COG1610	YqeY-like protein
CYFUS_RS35855	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CYFUS_RS35870	COG0583	DNA-binding transcription factor activity
CYFUS_RS35875	COG0625	glutathione transferase activity
CYFUS_RS35880	COG0667	Aldo Keto reductase
CYFUS_RS35895	COG1278	Cold shock
CYFUS_RS35905	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS35910	COG2205	protein histidine kinase activity
CYFUS_RS35930	COG0109	protoheme IX farnesyltransferase activity
CYFUS_RS35950	COG0443	Heat shock 70 kDa protein
CYFUS_RS35955	COG0443	Heat shock 70 kDa protein
CYFUS_RS35960	COG0204	Acyl-transferase
CYFUS_RS35960	COG0318	PFAM AMP-dependent synthetase and ligase
CYFUS_RS35965	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS36000	COG0737	Belongs to the 5'-nucleotidase family
CYFUS_RS36020	COG0463	Glycosyl transferase, family 2
CYFUS_RS36025	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CYFUS_RS36040	COG0493	'glutamate synthase
CYFUS_RS36040	COG0543	2 iron, 2 sulfur cluster binding
CYFUS_RS36050	COG2062	phosphohistidine phosphatase, SixA
CYFUS_RS36065	COG0233	cytoplasmic translational termination
CYFUS_RS36070	COG0528	UMP kinase activity
CYFUS_RS36075	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CYFUS_RS36080	COG0052	Belongs to the universal ribosomal protein uS2 family
CYFUS_RS36085	COG0653	protein targeting
CYFUS_RS36090	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CYFUS_RS36100	COG0739	heme binding
CYFUS_RS36105	COG0631	protein serine/threonine phosphatase activity
CYFUS_RS36110	COG0497	DNA recombination
CYFUS_RS36115	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CYFUS_RS36120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CYFUS_RS36125	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CYFUS_RS36140	COG1309	transcriptional regulator
CYFUS_RS36150	COG0737	Belongs to the 5'-nucleotidase family
CYFUS_RS36160	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CYFUS_RS36165	COG0673	inositol 2-dehydrogenase activity
CYFUS_RS36175	COG1879	ABC-type sugar transport system periplasmic component
CYFUS_RS36180	COG1172	Belongs to the binding-protein-dependent transport system permease family
CYFUS_RS36185	COG1129	ABC transporter
CYFUS_RS36195	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CYFUS_RS36215	COG0463	Glycosyl transferase, family 2
CYFUS_RS36220	COG3394	polysaccharide catabolic process
CYFUS_RS36225	COG2264	protein methyltransferase activity
CYFUS_RS36235	COG2936	dipeptidyl-peptidase activity
CYFUS_RS36240	COG1024	Enoyl-CoA hydratase
CYFUS_RS36240	COG1250	3-hydroxyacyl-CoA dehydrogenase
CYFUS_RS36245	COG0183	Belongs to the thiolase family
CYFUS_RS36250	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CYFUS_RS36265	COG2133	pyrroloquinoline quinone binding
CYFUS_RS36285	COG4581	dead DEAH box helicase
CYFUS_RS36295	COG0583	DNA-binding transcription factor activity
CYFUS_RS36350	COG1830	Aldolase
CYFUS_RS36360	COG2132	Multicopper oxidase
CYFUS_RS36375	COG2205	protein histidine kinase activity
CYFUS_RS36400	COG0515	serine threonine protein kinase
CYFUS_RS36405	COG0616	signal peptide processing
CYFUS_RS36430	COG0515	serine threonine protein kinase
CYFUS_RS36440	COG3227	Zinc metalloprotease (Elastase)
CYFUS_RS36450	COG2080	2 iron, 2 sulfur cluster binding
CYFUS_RS36475	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CYFUS_RS36490	COG0617	tRNA 3'-terminal CCA addition
CYFUS_RS36525	COG0583	DNA-binding transcription factor activity
CYFUS_RS36530	COG0778	Nitroreductase
CYFUS_RS36570	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CYFUS_RS36640	COG0768	penicillin binding
CYFUS_RS36645	COG0367	asparagine synthase
CYFUS_RS36695	COG3209	COG3209 Rhs family protein
CYFUS_RS36710	COG0730	response to heat
CYFUS_RS36715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CYFUS_RS36720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CYFUS_RS36725	COG2204	response regulator
CYFUS_RS36730	COG0446	pyridine nucleotide-disulphide oxidoreductase
CYFUS_RS36755	COG2223	nitrite transmembrane transporter activity
CYFUS_RS36760	COG3227	Zinc metalloprotease (Elastase)
CYFUS_RS36770	COG1902	pentaerythritol trinitrate reductase activity
CYFUS_RS36775	COG2202	Pas domain
CYFUS_RS36775	COG2205	protein histidine kinase activity
CYFUS_RS36835	COG1858	cytochrome C peroxidase
CYFUS_RS36855	COG1858	cytochrome C peroxidase
CYFUS_RS36860	COG3148	PFAM DTW domain containing protein
CYFUS_RS36875	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CYFUS_RS36880	COG0271	Belongs to the BolA IbaG family
CYFUS_RS36885	COG1678	Uncharacterized ACR, COG1678
CYFUS_RS36890	COG4565	transcriptional regulatory protein
CYFUS_RS36905	COG4166	transmembrane transport
CYFUS_RS36915	COG1505	serine-type exopeptidase activity
CYFUS_RS36925	COG0740	serine-type endopeptidase activity
CYFUS_RS36930	COG0544	peptidyl-prolyl cis-trans isomerase activity
CYFUS_RS36960	COG0024	Methionine aminopeptidase
CYFUS_RS36975	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CYFUS_RS36980	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CYFUS_RS36985	COG0860	N-Acetylmuramoyl-L-alanine amidase
CYFUS_RS36990	COG0709	Synthesizes selenophosphate from selenide and ATP
CYFUS_RS37005	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CYFUS_RS37030	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CYFUS_RS37035	COG0210	DNA helicase
CYFUS_RS37080	COG0084	hydrolase, TatD family'
CYFUS_RS37085	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CYFUS_RS37095	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS37140	COG2072	flavoprotein involved in K transport
CYFUS_RS37150	COG1657	PFAM Prenyltransferase squalene oxidase
CYFUS_RS37160	COG1832	CoA-binding protein
CYFUS_RS37175	COG4124	Belongs to the glycosyl hydrolase 26 family
CYFUS_RS37225	COG3425	synthase
CYFUS_RS37240	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CYFUS_RS37245	COG1309	transcriptional regulator
CYFUS_RS37250	COG2205	protein histidine kinase activity
CYFUS_RS37250	COG2198	Histidine kinase
CYFUS_RS37250	COG0784	Response regulator, receiver
CYFUS_RS37255	COG0315	cyclic pyranopterin monophosphate synthase activity
CYFUS_RS37265	COG0492	ferredoxin-NADP+ reductase activity
CYFUS_RS37270	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CYFUS_RS37275	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS37305	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS37310	COG1169	isochorismate synthase
CYFUS_RS37315	COG1021	2,3-dihydroxybenzoate-AMP ligase
CYFUS_RS37320	COG3433	isochorismatase activity
CYFUS_RS37320	COG1535	isochorismatase
CYFUS_RS37325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CYFUS_RS37330	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CYFUS_RS37335	COG4206	TonB-dependent receptor
CYFUS_RS37345	COG0811	peptide transport
CYFUS_RS37375	COG1045	serine acetyltransferase
CYFUS_RS37440	COG5002	protein histidine kinase activity
CYFUS_RS37460	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CYFUS_RS37465	COG0753	catalase activity
CYFUS_RS37470	COG1506	peptidase
CYFUS_RS37470	COG0823	Involved in the tonB-independent uptake of proteins
CYFUS_RS37480	COG2363	Small membrane protein
CYFUS_RS37500	COG5002	protein histidine kinase activity
CYFUS_RS37505	COG3850	Histidine kinase
CYFUS_RS37505	COG2205	protein histidine kinase activity
CYFUS_RS37505	COG2205	protein histidine kinase activity
CYFUS_RS37505	COG3437	response regulator, receiver
CYFUS_RS37505	COG3437	response regulator, receiver
CYFUS_RS37505	COG4999	Histidine kinase
CYFUS_RS37505	COG4999	Histidine kinase
CYFUS_RS37505	COG3850	Histidine kinase
CYFUS_RS37510	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CYFUS_RS37530	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CYFUS_RS37545	COG2226	methyltransferase
CYFUS_RS37550	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CYFUS_RS37560	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CYFUS_RS37575	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CYFUS_RS37610	COG2814	Major facilitator Superfamily
CYFUS_RS37615	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CYFUS_RS37620	COG1335	isochorismatase
CYFUS_RS37630	COG2197	response regulator
CYFUS_RS37635	COG4585	Histidine kinase
CYFUS_RS37640	COG2267	carboxylic ester hydrolase activity
CYFUS_RS37645	COG2124	cytochrome p450
CYFUS_RS37650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CYFUS_RS37660	COG1032	radical SAM domain protein
CYFUS_RS37665	COG0546	phosphoglycolate phosphatase activity
CYFUS_RS37680	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS37745	COG2124	cytochrome p450
CYFUS_RS37755	COG0243	molybdopterin cofactor binding
CYFUS_RS37760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CYFUS_RS37765	COG2146	nitrite reductase [NAD(P)H] activity
CYFUS_RS37775	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CYFUS_RS37795	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS37805	COG1063	alcohol dehydrogenase
CYFUS_RS37830	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CYFUS_RS37840	COG0300	oxidoreductase activity
CYFUS_RS37855	COG2815	serine threonine protein kinase
CYFUS_RS37855	COG0515	serine threonine protein kinase
CYFUS_RS37885	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS37890	COG2201	protein-glutamate methylesterase activity
CYFUS_RS37905	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CYFUS_RS37915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CYFUS_RS37950	COG1454	alcohol dehydrogenase
CYFUS_RS37965	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CYFUS_RS37980	COG0300	oxidoreductase activity
CYFUS_RS37985	COG4968	Prepilin-type N-terminal cleavage methylation domain
CYFUS_RS38035	COG1595	DNA-templated transcription, initiation
CYFUS_RS38040	COG0659	secondary active sulfate transmembrane transporter activity
CYFUS_RS38045	COG3002	Belongs to the UPF0753 family
CYFUS_RS38050	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CYFUS_RS38080	COG1744	ABC transporter substrate-binding protein PnrA-like
CYFUS_RS38115	COG2339	peptidase activity
CYFUS_RS38135	COG4447	cellulose binding
CYFUS_RS38135	COG4733	cellulase activity
CYFUS_RS38140	COG4733	cellulase activity
CYFUS_RS38140	COG5297	Belongs to the glycosyl hydrolase family 6
CYFUS_RS38145	COG2723	6-phospho-beta-galactosidase activity
CYFUS_RS38185	COG2879	small protein
CYFUS_RS38190	COG1966	Carbon starvation protein
CYFUS_RS38225	COG4774	siderophore transport
CYFUS_RS38235	COG2706	6-phosphogluconolactonase activity
CYFUS_RS38250	COG0583	DNA-binding transcription factor activity
CYFUS_RS38280	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CYFUS_RS38340	COG2814	Major facilitator Superfamily
CYFUS_RS38380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CYFUS_RS38395	COG2205	protein histidine kinase activity
CYFUS_RS38400	COG3227	Zinc metalloprotease (Elastase)
CYFUS_RS38410	COG2815	serine threonine protein kinase
CYFUS_RS38410	COG0515	serine threonine protein kinase
CYFUS_RS38450	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CYFUS_RS38460	COG1609	Transcriptional regulator
CYFUS_RS38520	COG0667	Aldo Keto reductase
CYFUS_RS38545	COG0515	serine threonine protein kinase
CYFUS_RS38555	COG0352	thiamine-phosphate diphosphorylase activity
CYFUS_RS38560	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CYFUS_RS38575	COG5002	protein histidine kinase activity
CYFUS_RS38580	COG1960	acyl-CoA dehydrogenase activity
CYFUS_RS38650	COG1132	(ABC) transporter
CYFUS_RS38650	COG2375	cellular response to nickel ion
CYFUS_RS38655	COG1132	(ABC) transporter
CYFUS_RS38660	COG4106	trans-aconitate 2-methyltransferase activity
CYFUS_RS38665	COG0583	DNA-binding transcription factor activity
CYFUS_RS38710	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS38755	COG2079	MmgE PrpD family protein
CYFUS_RS38760	COG0028	Belongs to the TPP enzyme family
CYFUS_RS38805	COG0625	glutathione transferase activity
CYFUS_RS38840	COG0346	lactoylglutathione lyase activity
CYFUS_RS38865	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CYFUS_RS38870	COG0583	DNA-binding transcription factor activity
CYFUS_RS38890	COG3275	phosphorelay sensor kinase activity
CYFUS_RS38895	COG3279	Response regulator of the LytR AlgR family
CYFUS_RS38980	COG0456	acetyltransferase
CYFUS_RS38995	COG0612	Peptidase, M16
CYFUS_RS39030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CYFUS_RS39045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CYFUS_RS39065	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CYFUS_RS39070	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CYFUS_RS39080	COG2815	serine threonine protein kinase
CYFUS_RS39080	COG0515	serine threonine protein kinase
CYFUS_RS39085	COG0756	dUTP diphosphatase activity
CYFUS_RS39090	COG0739	heme binding
CYFUS_RS39100	COG1185	polyribonucleotide nucleotidyltransferase activity
CYFUS_RS39115	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CYFUS_RS39145	COG0779	Required for maturation of 30S ribosomal subunits
CYFUS_RS39165	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CYFUS_RS39165	COG2199	diguanylate cyclase activity
CYFUS_RS39185	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CYFUS_RS39190	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CYFUS_RS39195	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CYFUS_RS39200	COG1428	Deoxynucleoside kinase
CYFUS_RS39215	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CYFUS_RS39220	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CYFUS_RS39230	COG0484	heat shock protein binding
CYFUS_RS39235	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CYFUS_RS39245	COG0631	protein serine/threonine phosphatase activity
CYFUS_RS39250	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CYFUS_RS39270	COG0457	Tetratricopeptide repeat
CYFUS_RS39275	COG0626	cystathionine gamma-synthase activity
CYFUS_RS39300	COG0667	Aldo Keto reductase
CYFUS_RS39340	COG0842	Transport permease protein
CYFUS_RS39345	COG1131	(ABC) transporter
CYFUS_RS39405	COG3030	protein affecting phage T7 exclusion by the F plasmid
CYFUS_RS39430	COG1929	Belongs to the glycerate kinase type-1 family
CYFUS_RS39440	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CYFUS_RS39450	COG4977	sequence-specific DNA binding
CYFUS_RS39480	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CYFUS_RS39495	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CYFUS_RS39505	COG2814	Major facilitator Superfamily
CYFUS_RS39560	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CYFUS_RS39570	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS39580	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CYFUS_RS39585	COG0439	Biotin carboxylase
CYFUS_RS39595	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CYFUS_RS39610	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CYFUS_RS39620	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CYFUS_RS39625	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CYFUS_RS39630	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CYFUS_RS39635	COG0772	Belongs to the SEDS family
CYFUS_RS39640	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CYFUS_RS39645	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CYFUS_RS39650	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CYFUS_RS39655	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CYFUS_RS39665	COG3116	cell division
CYFUS_RS39670	COG0275	rRNA processing
CYFUS_RS39725	COG1454	alcohol dehydrogenase
CYFUS_RS39735	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CYFUS_RS39735	COG0519	Catalyzes the synthesis of GMP from XMP
CYFUS_RS39745	COG0628	permease
CYFUS_RS39755	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CYFUS_RS39760	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CYFUS_RS39765	COG1254	Belongs to the acylphosphatase family
CYFUS_RS39780	COG1295	ribonuclease BN
CYFUS_RS39790	COG4789	Type iii secretion
CYFUS_RS39795	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CYFUS_RS39800	COG1684	flagellar biosynthetic protein fliR
CYFUS_RS39805	COG1987	bacterial-type flagellum assembly
CYFUS_RS39810	COG4790	Type iii secretion
CYFUS_RS39830	COG4669	(LipO)protein
CYFUS_RS39850	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS39860	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CYFUS_RS39865	COG1404	Belongs to the peptidase S8 family
CYFUS_RS39890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CYFUS_RS39940	COG3597	protein domain associated with
CYFUS_RS39955	COG0423	glycine-tRNA ligase activity
CYFUS_RS39980	COG0457	Tetratricopeptide repeat
CYFUS_RS40005	COG0714	Associated with various cellular activities
CYFUS_RS40065	COG0475	glutathione-regulated potassium exporter activity
CYFUS_RS40095	COG0318	PFAM AMP-dependent synthetase and ligase
CYFUS_RS40170	COG3541	Predicted nucleotidyltransferase
CYFUS_RS40200	COG0668	transmembrane transport
CYFUS_RS40215	COG0741	lytic transglycosylase activity
CYFUS_RS40215	COG1388	LysM domain
CYFUS_RS40225	COG0515	serine threonine protein kinase
CYFUS_RS40235	COG0577	efflux transmembrane transporter activity
CYFUS_RS40235	COG1136	(ABC) transporter
CYFUS_RS40240	COG1136	(ABC) transporter
CYFUS_RS40265	COG0402	S-adenosylhomocysteine deaminase activity
CYFUS_RS40290	COG3845	ABC transporter
CYFUS_RS40295	COG4603	Belongs to the binding-protein-dependent transport system permease family
CYFUS_RS40300	COG1079	Belongs to the binding-protein-dependent transport system permease family
CYFUS_RS40305	COG5002	protein histidine kinase activity
CYFUS_RS40315	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CYFUS_RS40325	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CYFUS_RS40330	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CYFUS_RS40375	COG0552	protein localization to endoplasmic reticulum
CYFUS_RS40400	COG1215	transferase activity, transferring glycosyl groups
CYFUS_RS40405	COG1181	Belongs to the D-alanine--D-alanine ligase family
CYFUS_RS40435	COG1741	Belongs to the pirin family
CYFUS_RS40440	COG4122	O-methyltransferase activity
CYFUS_RS40445	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CYFUS_RS40450	COG0583	DNA-binding transcription factor activity
CYFUS_RS40465	COG0753	catalase activity
CYFUS_RS40490	COG0793	Belongs to the peptidase S41A family
CYFUS_RS40500	COG0673	inositol 2-dehydrogenase activity
CYFUS_RS40505	COG4942	peptidase
CYFUS_RS40510	COG2177	Part of the ABC transporter FtsEX involved in
CYFUS_RS40515	COG2884	Cell division ATP-binding protein ftsE
CYFUS_RS40530	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CYFUS_RS40540	COG0811	peptide transport
CYFUS_RS40555	COG0823	Involved in the tonB-independent uptake of proteins
CYFUS_RS40560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CYFUS_RS40565	COG0248	Ppx GppA phosphatase
CYFUS_RS40575	COG1902	pentaerythritol trinitrate reductase activity
CYFUS_RS40605	COG3267	Type II secretory pathway component ExeA
CYFUS_RS40605	COG3409	Peptidoglycan-binding domain 1 protein
CYFUS_RS40615	COG0439	Biotin carboxylase
CYFUS_RS40625	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CYFUS_RS40665	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CYFUS_RS40670	COG4968	Prepilin-type N-terminal cleavage methylation domain
CYFUS_RS40680	COG1131	(ABC) transporter
CYFUS_RS40695	COG3852	Histidine kinase
CYFUS_RS40700	COG1459	type II secretion system
CYFUS_RS40710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CYFUS_RS40720	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CYFUS_RS40750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CYFUS_RS40750	COG1199	ATP-dependent helicase activity
CYFUS_RS40780	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CYFUS_RS40790	COG0443	Heat shock 70 kDa protein
CYFUS_RS40810	COG0793	Belongs to the peptidase S41A family
CYFUS_RS40820	COG0584	glycerophosphoryl diester phosphodiesterase
CYFUS_RS40895	COG3209	COG3209 Rhs family protein
CYFUS_RS40925	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CYFUS_RS40945	COG5002	protein histidine kinase activity
CYFUS_RS40950	COG2766	serine protein kinase
CYFUS_RS40955	COG2718	Belongs to the UPF0229 family
CYFUS_RS40960	COG2719	SpoVR family
CYFUS_RS40965	COG0739	heme binding
CYFUS_RS40980	COG0058	SHG alpha-glucan phosphorylase activity
CYFUS_RS40995	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS41000	COG0587	DNA-directed DNA polymerase activity
CYFUS_RS41060	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CYFUS_RS41065	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CYFUS_RS41080	COG0583	DNA-binding transcription factor activity
CYFUS_RS41085	COG2814	Major facilitator Superfamily
CYFUS_RS41090	COG0667	Aldo Keto reductase
CYFUS_RS41105	COG0326	Molecular chaperone. Has ATPase activity
CYFUS_RS41230	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CYFUS_RS41255	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CYFUS_RS41270	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CYFUS_RS41275	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CYFUS_RS41315	COG3590	peptidase
CYFUS_RS41330	COG0516	GMP reductase activity
CYFUS_RS41340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CYFUS_RS41425	COG4733	cellulase activity
CYFUS_RS41465	COG1755	Isoprenylcysteine carboxyl methyltransferase
CYFUS_RS41470	COG0644	oxidoreductase
CYFUS_RS41480	COG2353	YceI-like domain
CYFUS_RS41505	COG0183	Belongs to the thiolase family
CYFUS_RS41525	COG1012	belongs to the aldehyde dehydrogenase family
CYFUS_RS41535	COG0737	Belongs to the 5'-nucleotidase family
CYFUS_RS41540	COG5002	protein histidine kinase activity
CYFUS_RS41545	COG0813	purine-nucleoside phosphorylase activity
CYFUS_RS41550	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CYFUS_RS41560	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CYFUS_RS41600	COG0805	protein transport
CYFUS_RS41605	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CYFUS_RS41615	COG0123	including yeast histone deacetylase and acetoin utilization protein
CYFUS_RS41625	COG0625	glutathione transferase activity
CYFUS_RS41675	COG0300	oxidoreductase activity
CYFUS_RS41695	COG1793	dna ligase
CYFUS_RS41695	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CYFUS_RS41700	COG5002	protein histidine kinase activity
CYFUS_RS41720	COG2086	electron transfer activity
CYFUS_RS41725	COG1960	acyl-CoA dehydrogenase activity
CYFUS_RS41730	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CYFUS_RS41740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CYFUS_RS41750	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CYFUS_RS41755	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CYFUS_RS41760	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CYFUS_RS41780	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CYFUS_RS41790	COG0515	serine threonine protein kinase
CYFUS_RS41815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CYFUS_RS41890	COG0438	transferase activity, transferring glycosyl groups
CYFUS_RS41900	COG0438	transferase activity, transferring glycosyl groups
CYFUS_RS41915	COG1295	ribonuclease BN
CYFUS_RS41925	COG0697	spore germination
CYFUS_RS41930	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CYFUS_RS41935	COG2096	Adenosyltransferase
CYFUS_RS41940	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CYFUS_RS41955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CYFUS_RS41965	COG1181	Belongs to the D-alanine--D-alanine ligase family
CYFUS_RS42035	COG0583	DNA-binding transcription factor activity
CYFUS_RS42065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CYFUS_RS42080	COG0697	spore germination
CYFUS_RS42090	COG1331	Highly conserved protein containing a thioredoxin domain
CYFUS_RS42100	COG2326	polyphosphate kinase activity
CYFUS_RS42150	COG2204	response regulator
CYFUS_RS42165	COG0657	acetylesterase activity
CYFUS_RS42180	COG1846	Transcriptional regulator
CYFUS_RS42190	COG2072	flavoprotein involved in K transport
CYFUS_RS42220	COG0596	Alpha beta hydrolase
CYFUS_RS42220	COG0508	dehydrogenase complex catalyzes the overall conversion of
CYFUS_RS42230	COG0515	serine threonine protein kinase
CYFUS_RS42235	COG4558	Periplasmic binding protein
CYFUS_RS42240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CYFUS_RS42245	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CYFUS_RS42260	COG0037	tRNA processing
CYFUS_RS42290	COG0366	Alpha amylase catalytic
CYFUS_RS42295	COG5002	protein histidine kinase activity
CYFUS_RS42325	COG0477	Major facilitator Superfamily
CYFUS_RS42330	COG2816	NAD+ diphosphatase activity
CYFUS_RS42355	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CYFUS_RS42365	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CYFUS_RS42395	COG2264	protein methyltransferase activity
CYFUS_RS42400	COG2169	Transcriptional regulator
CYFUS_RS42400	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CYFUS_RS42455	COG1309	transcriptional regulator
CYFUS_RS42465	COG3220	belongs to the UPF0276 family
CYFUS_RS42585	COG0583	DNA-binding transcription factor activity
CYFUS_RS42640	COG1131	(ABC) transporter
CYFUS_RS42650	COG1047	Peptidyl-prolyl cis-trans
CYFUS_RS42660	COG2197	response regulator
CYFUS_RS42670	COG4191	Histidine kinase
CYFUS_RS42680	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CYFUS_RS42705	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CYFUS_RS42710	COG0542	response to heat
CYFUS_RS42720	COG2201	protein-glutamate methylesterase activity
CYFUS_RS42735	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CYFUS_RS42745	COG2201	protein-glutamate methylesterase activity
CYFUS_RS42750	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CYFUS_RS42760	COG0508	dehydrogenase complex catalyzes the overall conversion of
CYFUS_RS42765	COG1278	Cold shock
CYFUS_RS42780	COG0840	transmembrane signaling receptor activity
CYFUS_RS42805	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS42810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CYFUS_RS42815	COG0004	ammonium transporteR
CYFUS_RS42825	COG4771	TonB-dependent receptor
CYFUS_RS42835	COG2204	response regulator
CYFUS_RS42840	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CYFUS_RS42845	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CYFUS_RS42895	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CYFUS_RS42900	COG0134	indole-3-glycerol-phosphate synthase activity
CYFUS_RS42905	COG0135	phosphoribosylanthranilate isomerase activity
CYFUS_RS42910	COG0133	tryptophan synthase activity
CYFUS_RS42915	COG0159	tryptophan synthase activity
CYFUS_RS42925	COG0406	alpha-ribazole phosphatase activity
CYFUS_RS43000	COG0300	oxidoreductase activity
CYFUS_RS43015	COG0437	4 iron, 4 sulfur cluster binding
CYFUS_RS43050	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CYFUS_RS43060	COG1845	cytochrome c oxidase, subunit III
CYFUS_RS43115	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CYFUS_RS43175	COG3507	Belongs to the glycosyl hydrolase 43 family
CYFUS_RS43200	COG0515	serine threonine protein kinase
CYFUS_RS43210	COG2124	cytochrome p450
CYFUS_RS43220	COG0515	serine threonine protein kinase
CYFUS_RS43245	COG1940	carbohydrate kinase activity
CYFUS_RS43250	COG4213	ABC transporter substrate-binding protein
CYFUS_RS43265	COG3064	Membrane
CYFUS_RS43265	COG4991	sh3 domain protein
CYFUS_RS43265	COG0515	serine threonine protein kinase
CYFUS_RS43305	COG0666	response to abiotic stimulus
CYFUS_RS43355	COG1874	Beta-galactosidase
CYFUS_RS43355	COG0366	Alpha amylase catalytic
CYFUS_RS43360	COG2124	cytochrome p450
CYFUS_RS43370	COG5002	protein histidine kinase activity
CYFUS_RS43380	COG0477	Major facilitator Superfamily
CYFUS_RS43385	COG0668	transmembrane transport
CYFUS_RS43390	COG0427	acetyl-CoA hydrolase
CYFUS_RS43410	COG2249	NAD(P)H dehydrogenase (quinone) activity
CYFUS_RS43415	COG1733	regulation of RNA biosynthetic process
CYFUS_RS43420	COG1881	PFAM PEBP family protein
CYFUS_RS43425	COG0625	glutathione transferase activity
CYFUS_RS43515	COG0582	viral genome integration into host DNA
CYFUS_RS43530	COG0784	Response regulator, receiver
CYFUS_RS43535	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CYFUS_RS43540	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CYFUS_RS43560	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CYFUS_RS43605	COG3256	nitric oxide reductase
CYFUS_RS43615	COG2223	nitrite transmembrane transporter activity
CYFUS_RS43685	COG0564	pseudouridine synthase activity
CYFUS_RS43695	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CYFUS_RS43730	COG5002	protein histidine kinase activity
CYFUS_RS43740	COG3206	protein involved in exopolysaccharide biosynthesis
CYFUS_RS43740	COG0489	protein tyrosine kinase activity
CYFUS_RS43760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CYFUS_RS43765	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CYFUS_RS43780	COG1086	Polysaccharide biosynthesis protein
CYFUS_RS43800	COG4412	M6 family metalloprotease domain protein
CYFUS_RS43800	COG1404	Belongs to the peptidase S8 family
CYFUS_RS43820	COG3866	Pectate lyase
CYFUS_RS43835	COG2271	Major facilitator Superfamily
CYFUS_RS43840	COG1609	Transcriptional regulator
CYFUS_RS43845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CYFUS_RS43880	COG0515	serine threonine protein kinase
CYFUS_RS43880	COG2815	serine threonine protein kinase
CYFUS_RS43905	COG1131	(ABC) transporter
CYFUS_RS43915	COG2124	cytochrome p450
CYFUS_RS43920	COG2706	6-phosphogluconolactonase activity
CYFUS_RS43935	COG0076	glutamate decarboxylase activity
CYFUS_RS43965	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS43970	COG2205	protein histidine kinase activity
CYFUS_RS44000	COG5492	domain, Protein
CYFUS_RS44000	COG4932	domain protein
CYFUS_RS44015	COG4566	intracellular signal transduction
CYFUS_RS44020	COG4191	Histidine kinase
CYFUS_RS44035	COG1297	OPT oligopeptide transporter protein
CYFUS_RS44040	COG0515	serine threonine protein kinase
CYFUS_RS44050	COG1733	regulation of RNA biosynthetic process
CYFUS_RS44055	COG0604	alcohol dehydrogenase
CYFUS_RS44060	COG1024	Enoyl-CoA hydratase
CYFUS_RS44060	COG1250	3-hydroxyacyl-CoA dehydrogenase
CYFUS_RS44075	COG1106	Psort location Cytoplasmic, score
CYFUS_RS44080	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CYFUS_RS44090	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CYFUS_RS44100	COG0069	glutamate synthase activity
CYFUS_RS44100	COG0070	glutamate synthase
CYFUS_RS44100	COG0067	glutamate synthase
CYFUS_RS44105	COG2205	protein histidine kinase activity
CYFUS_RS44110	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CYFUS_RS44120	COG2815	serine threonine protein kinase
CYFUS_RS44120	COG0515	serine threonine protein kinase
CYFUS_RS44125	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS44130	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CYFUS_RS44140	COG0248	Ppx GppA phosphatase
CYFUS_RS44235	COG0473	3-isopropylmalate dehydrogenase activity
CYFUS_RS44240	COG0023	Translation Initiation Factor
CYFUS_RS44255	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CYFUS_RS44270	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CYFUS_RS44275	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CYFUS_RS44315	COG2072	flavoprotein involved in K transport
CYFUS_RS44335	COG0475	glutathione-regulated potassium exporter activity
CYFUS_RS44340	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS44345	COG2205	protein histidine kinase activity
CYFUS_RS44350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CYFUS_RS44355	COG1136	(ABC) transporter
CYFUS_RS44355	COG0577	efflux transmembrane transporter activity
CYFUS_RS44360	COG0577	efflux transmembrane transporter activity
CYFUS_RS44360	COG1136	(ABC) transporter
CYFUS_RS44370	COG0515	serine threonine protein kinase
CYFUS_RS44370	COG2815	serine threonine protein kinase
CYFUS_RS44390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CYFUS_RS44395	COG0277	FAD linked oxidase domain protein
CYFUS_RS44420	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CYFUS_RS44425	COG0741	lytic transglycosylase activity
CYFUS_RS44435	COG0363	glucosamine-6-phosphate deaminase activity
CYFUS_RS44525	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CYFUS_RS44555	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CYFUS_RS44565	COG0823	Involved in the tonB-independent uptake of proteins
CYFUS_RS44615	COG4580	involved in the transport of maltose and maltodextrins
CYFUS_RS44635	COG1858	cytochrome C peroxidase
CYFUS_RS44640	COG1858	cytochrome C peroxidase
CYFUS_RS44680	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CYFUS_RS44685	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CYFUS_RS44695	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CYFUS_RS44715	COG1022	Amp-dependent synthetase and ligase
CYFUS_RS44725	COG0501	Belongs to the peptidase M48B family
CYFUS_RS44730	COG4085	toxin activity
CYFUS_RS44730	COG0737	Belongs to the 5'-nucleotidase family
CYFUS_RS44730	COG1525	nuclease
CYFUS_RS44745	COG0740	serine-type endopeptidase activity
CYFUS_RS44760	COG0114	fumarate hydratase activity
CYFUS_RS44780	COG2224	Isocitrate lyase
CYFUS_RS44810	COG5002	protein histidine kinase activity
CYFUS_RS44820	COG2132	Multicopper oxidase
CYFUS_RS44840	COG4717	serine-type aminopeptidase activity
CYFUS_RS44845	COG0420	3'-5' exonuclease activity
CYFUS_RS44850	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CYFUS_RS44950	COG2815	serine threonine protein kinase
CYFUS_RS44950	COG0515	serine threonine protein kinase
CYFUS_RS45010	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CYFUS_RS45025	COG2094	Belongs to the DNA glycosylase MPG family
CYFUS_RS45030	COG1640	4-alpha-glucanotransferase
CYFUS_RS45040	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CYFUS_RS45055	COG0038	chloride channel
CYFUS_RS45075	COG2204	response regulator
CYFUS_RS45085	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CYFUS_RS45085	COG1672	PFAM Archaeal ATPase
CYFUS_RS45100	COG0659	secondary active sulfate transmembrane transporter activity
CYFUS_RS45135	COG2815	serine threonine protein kinase
CYFUS_RS45135	COG0515	serine threonine protein kinase
CYFUS_RS45140	COG0402	S-adenosylhomocysteine deaminase activity
CYFUS_RS45160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CYFUS_RS45205	COG0517	IMP dehydrogenase activity
CYFUS_RS45205	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CYFUS_RS45215	COG0840	transmembrane signaling receptor activity
CYFUS_RS45225	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CYFUS_RS45240	COG2267	carboxylic ester hydrolase activity
CYFUS_RS45250	COG2205	protein histidine kinase activity
CYFUS_RS45265	COG2239	Acts as a magnesium transporter
CYFUS_RS45270	COG2124	cytochrome p450
CYFUS_RS45380	COG3220	belongs to the UPF0276 family
CYFUS_RS45410	COG1131	(ABC) transporter
CYFUS_RS45420	COG0714	Associated with various cellular activities
CYFUS_RS45430	COG1304	FMN binding
CYFUS_RS45495	COG2885	chlorophyll binding
CYFUS_RS45500	COG1744	ABC transporter substrate-binding protein PnrA-like
CYFUS_RS45530	COG4251	negative regulation of phosphorylation
CYFUS_RS45550	COG5464	transposase or invertase
CYFUS_RS45625	COG0681	Belongs to the peptidase S26 family
CYFUS_RS45630	COG1621	beta-fructofuranosidase activity
CYFUS_RS45640	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CYFUS_RS45655	COG1902	pentaerythritol trinitrate reductase activity
CYFUS_RS45685	COG1902	pentaerythritol trinitrate reductase activity
CYFUS_RS45770	COG2815	serine threonine protein kinase
CYFUS_RS45770	COG0515	serine threonine protein kinase
CYFUS_RS45795	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CYFUS_RS45820	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS45830	COG1968	undecaprenyl-diphosphatase activity
CYFUS_RS45835	COG3012	SEC-C Motif Domain Protein
CYFUS_RS45865	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CYFUS_RS45890	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CYFUS_RS45905	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CYFUS_RS45915	COG0804	urea catabolic process
CYFUS_RS45920	COG0832	Belongs to the urease beta subunit family
CYFUS_RS45920	COG0831	urea catabolic process
CYFUS_RS45925	COG0829	nickel cation binding
CYFUS_RS45940	COG5297	Belongs to the glycosyl hydrolase family 6
CYFUS_RS45975	COG0028	Belongs to the TPP enzyme family
CYFUS_RS45980	COG0277	FAD linked oxidase domain protein
CYFUS_RS45980	COG0247	lactate metabolic process
CYFUS_RS45990	COG3387	PFAM Glycoside hydrolase 15-related
CYFUS_RS46040	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS46045	COG0642	Histidine kinase
CYFUS_RS46045	COG3850	Histidine kinase
CYFUS_RS46050	COG1070	Carbohydrate kinase
CYFUS_RS46065	COG0306	phosphate transporter
CYFUS_RS46075	COG1285	pathogenesis
CYFUS_RS46085	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CYFUS_RS46095	COG3716	PTS system mannose fructose sorbose family IID component
CYFUS_RS46105	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CYFUS_RS46110	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CYFUS_RS46110	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CYFUS_RS46115	COG1660	Displays ATPase and GTPase activities
CYFUS_RS46120	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CYFUS_RS46130	COG0537	adenosine 5'-monophosphoramidase activity
CYFUS_RS46135	COG0038	chloride channel
CYFUS_RS46155	COG0723	plastoquinol--plastocyanin reductase activity
CYFUS_RS46180	COG1716	ATPase activity
CYFUS_RS46230	COG1132	(ABC) transporter
CYFUS_RS46240	COG5002	protein histidine kinase activity
CYFUS_RS46255	COG0657	acetylesterase activity
CYFUS_RS46280	COG0596	Alpha beta hydrolase
CYFUS_RS46315	COG0668	transmembrane transport
CYFUS_RS46330	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CYFUS_RS46335	COG4208	sulfate ABC transporter
CYFUS_RS46340	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CYFUS_RS46360	COG1846	Transcriptional regulator
CYFUS_RS46375	COG1064	alcohol dehydrogenase
CYFUS_RS46390	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CYFUS_RS46430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CYFUS_RS46455	COG0477	Major facilitator Superfamily
CYFUS_RS46460	COG0443	Heat shock 70 kDa protein
CYFUS_RS46470	COG0714	Associated with various cellular activities
CYFUS_RS46485	COG3409	Peptidoglycan-binding domain 1 protein
CYFUS_RS46490	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CYFUS_RS46525	COG1846	Transcriptional regulator
CYFUS_RS46535	COG1472	Belongs to the glycosyl hydrolase 3 family
CYFUS_RS46555	COG0515	serine threonine protein kinase
CYFUS_RS46570	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CYFUS_RS46585	COG0477	Major facilitator Superfamily
CYFUS_RS46600	COG1181	Belongs to the D-alanine--D-alanine ligase family
CYFUS_RS46605	COG0657	acetylesterase activity
CYFUS_RS46635	COG0745	RESPONSE REGULATOR receiver
CYFUS_RS46645	COG0546	phosphoglycolate phosphatase activity
CYFUS_RS46645	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CYFUS_RS46650	COG0277	FAD linked oxidase domain protein
CYFUS_RS46670	COG3424	synthase
CYFUS_RS46675	COG0318	PFAM AMP-dependent synthetase and ligase
CYFUS_RS46685	COG0318	PFAM AMP-dependent synthetase and ligase
CYFUS_RS46690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CYFUS_RS46705	COG3268	Saccharopine dehydrogenase
CYFUS_RS46715	COG0442	prolyl-tRNA aminoacylation
CYFUS_RS46720	COG4085	toxin activity
CYFUS_RS46720	COG1525	nuclease
CYFUS_RS46720	COG0737	Belongs to the 5'-nucleotidase family
CYFUS_RS46725	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CYFUS_RS46765	COG0559	Belongs to the binding-protein-dependent transport system permease family
CYFUS_RS46785	COG0443	Heat shock 70 kDa protein
CYFUS_RS46790	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CYFUS_RS46810	COG4948	Mandelate Racemase Muconate Lactonizing
CYFUS_RS46815	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CYFUS_RS46820	COG1691	(AIR) carboxylase
CYFUS_RS46830	COG0366	Alpha amylase catalytic
CYFUS_RS46850	COG0395	ABC-type sugar transport system, permease component
CYFUS_RS46860	COG2182	Extracellular solute-binding protein
CYFUS_RS46865	COG3842	ATPase activity
CYFUS_RS46885	COG0643	Histidine kinase
CYFUS_RS46885	COG2198	Histidine kinase
CYFUS_RS46890	COG2201	protein-glutamate methylesterase activity
CYFUS_RS46895	COG0835	chemotaxis
CYFUS_RS46915	COG5002	protein histidine kinase activity
CYFUS_RS46920	COG1100	Small GTP-binding protein
CYFUS_RS46940	COG1199	ATP-dependent helicase activity
CYFUS_RS46950	COG0596	Alpha beta hydrolase
CYFUS_RS46985	COG2085	NADP oxidoreductase coenzyme F420-dependent
CYFUS_RS47020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CYFUS_RS47025	COG2072	flavoprotein involved in K transport
CYFUS_RS47030	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CYFUS_RS47035	COG4266	Belongs to the allantoicase family
CYFUS_RS47055	COG0386	Belongs to the glutathione peroxidase family
CYFUS_RS47060	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CYFUS_RS47090	COG0546	phosphoglycolate phosphatase activity
CYFUS_RS47095	COG1597	lipid kinase activity
CYFUS_RS47100	COG1420	regulation of RNA biosynthetic process
CYFUS_RS47105	COG0697	spore germination
CYFUS_RS47135	COG0183	Belongs to the thiolase family
CYFUS_RS47145	COG0025	NhaP-type Na H and K H
CYFUS_RS47150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CYFUS_RS47195	COG0408	coproporphyrinogen oxidase activity
CYFUS_RS47215	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS47220	COG0583	DNA-binding transcription factor activity
CYFUS_RS47230	COG2124	cytochrome p450
CYFUS_RS47230	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CYFUS_RS47250	COG0577	efflux transmembrane transporter activity
CYFUS_RS47290	COG1404	Belongs to the peptidase S8 family
CYFUS_RS47335	COG0642	Histidine kinase
CYFUS_RS47345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CYFUS_RS47355	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CYFUS_RS47360	COG2154	pterin-4-alpha-carbinolamine dehydratase
CYFUS_RS47375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CYFUS_RS47380	COG3781	membrane
CYFUS_RS47385	COG2171	N-acyltransferase activity
CYFUS_RS47395	COG0076	glutamate decarboxylase activity
CYFUS_RS47445	COG0583	DNA-binding transcription factor activity
CYFUS_RS47450	COG1902	pentaerythritol trinitrate reductase activity
CYFUS_RS47490	COG1215	transferase activity, transferring glycosyl groups
CYFUS_RS47500	COG1077	Cell shape determining protein MreB Mrl
CYFUS_RS47530	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CYFUS_RS47545	COG0308	aminopeptidase N
CYFUS_RS47550	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CYFUS_RS47610	COG1668	transmembrane transport
CYFUS_RS47615	COG4555	ABC transporter
CYFUS_RS47630	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CYFUS_RS47665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CYFUS_RS47680	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CYFUS_RS47680	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CYFUS_RS47695	COG2205	protein histidine kinase activity
CYFUS_RS47695	COG2198	Histidine kinase
CYFUS_RS47695	COG0784	Response regulator, receiver
CYFUS_RS47700	COG0546	phosphoglycolate phosphatase activity
CYFUS_RS47720	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CYFUS_RS47725	COG3852	Histidine kinase
CYFUS_RS47730	COG2205	protein histidine kinase activity
CYFUS_RS47775	COG2204	response regulator
CYFUS_RS47780	COG1160	GTP binding
CYFUS_RS47795	COG2885	chlorophyll binding
CYFUS_RS47795	COG3047	cAMP biosynthetic process
CYFUS_RS47825	COG0475	glutathione-regulated potassium exporter activity
CYFUS_RS47825	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CYFUS_RS47830	COG1301	dicarboxylic acid transport
CYFUS_RS47835	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CYFUS_RS47840	COG0515	serine threonine protein kinase
CYFUS_RS47840	COG2815	serine threonine protein kinase
CYFUS_RS47855	COG1022	Amp-dependent synthetase and ligase
CYFUS_RS47880	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CYFUS_RS47890	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CYFUS_RS47895	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CYFUS_RS47900	COG2949	membrane
CYFUS_RS47910	COG0628	permease
CYFUS_RS47920	COG3118	belongs to the thioredoxin family
CYFUS_RS47940	COG2205	protein histidine kinase activity
CYFUS_RS47950	COG0640	Transcriptional regulator
CYFUS_RS48015	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CYFUS_RS48030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CYFUS_RS48070	COG5297	Belongs to the glycosyl hydrolase family 6
CYFUS_RS48080	COG2814	Major facilitator Superfamily
CYFUS_RS48120	COG0588	phosphoglycerate mutase activity
CYFUS_RS48180	COG5002	protein histidine kinase activity
CYFUS_RS48185	COG0475	glutathione-regulated potassium exporter activity
CYFUS_RS48190	COG1396	sequence-specific DNA binding
CYFUS_RS48200	COG0835	chemotaxis
CYFUS_RS48210	COG0835	chemotaxis
CYFUS_RS48215	COG0840	transmembrane signaling receptor activity
CYFUS_RS48225	COG2201	protein-glutamate methylesterase activity
CYFUS_RS48230	COG2205	protein histidine kinase activity
CYFUS_RS48240	COG2723	6-phospho-beta-galactosidase activity
CYFUS_RS48255	COG1324	tolerance protein
CYFUS_RS48260	COG0666	response to abiotic stimulus
CYFUS_RS48280	COG0784	Response regulator, receiver
CYFUS_RS48280	COG2205	protein histidine kinase activity
CYFUS_RS48295	COG3119	arylsulfatase activity
CYFUS_RS48300	COG5002	protein histidine kinase activity
CYFUS_RS48300	COG3850	Histidine kinase
CYFUS_RS48305	COG0784	Response regulator, receiver
CYFUS_RS48425	COG5002	protein histidine kinase activity
CYFUS_RS48450	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CYFUS_RS48470	COG2261	transglycosylase associated protein
CYFUS_RS48500	COG2066	Belongs to the glutaminase family
CYFUS_RS48500	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CYFUS_RS48515	COG0515	serine threonine protein kinase
CYFUS_RS48525	COG0443	Heat shock 70 kDa protein
CYFUS_RS48590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CYFUS_RS48605	COG1012	belongs to the aldehyde dehydrogenase family
CYFUS_RS48645	COG0673	inositol 2-dehydrogenase activity
CYFUS_RS48665	COG0247	lactate metabolic process
CYFUS_RS48665	COG2181	nitrate reductase activity
CYFUS_RS48685	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CYFUS_RS48710	COG0848	biopolymer transport protein
CYFUS_RS48785	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CYFUS_RS48810	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CYFUS_RS48815	COG3387	PFAM Glycoside hydrolase 15-related
CYFUS_RS48825	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS48845	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CYFUS_RS48865	COG0583	DNA-binding transcription factor activity
CYFUS_RS48875	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CYFUS_RS48885	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CYFUS_RS48945	COG0242	peptide deformylase activity
CYFUS_RS48950	COG0737	Belongs to the 5'-nucleotidase family
CYFUS_RS48960	COG2204	response regulator
CYFUS_RS48965	COG3852	Histidine kinase
CYFUS_RS48985	COG2205	protein histidine kinase activity
CYFUS_RS48985	COG0784	Response regulator, receiver
CYFUS_RS49020	COG1984	allophanate hydrolase subunit 2
CYFUS_RS49025	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CYFUS_RS49035	COG2223	nitrite transmembrane transporter activity
CYFUS_RS49080	COG3953	SLT domain
CYFUS_RS49080	COG5280	Phage tail tape measure protein TP901
CYFUS_RS49090	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CYFUS_RS49100	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CYFUS_RS49105	COG0235	Class ii aldolase
CYFUS_RS49125	COG0003	Pfam Anion-transporting ATPase
CYFUS_RS49145	COG5002	protein histidine kinase activity
CYFUS_RS49190	COG3483	tryptophan 2,3-dioxygenase activity
CYFUS_RS49210	COG0506	proline dehydrogenase activity
CYFUS_RS49225	COG1739	Uncharacterized protein family UPF0029
CYFUS_RS49240	COG1028	Short-chain dehydrogenase reductase Sdr
CYFUS_RS49260	COG0243	molybdopterin cofactor binding
CYFUS_RS49260	COG3383	formate dehydrogenase (NAD+) activity
CYFUS_RS49265	COG0437	4 iron, 4 sulfur cluster binding
CYFUS_RS49305	COG0702	epimerase
CYFUS_RS49310	COG1733	regulation of RNA biosynthetic process
CYFUS_RS49325	COG0303	'Molybdopterin
CYFUS_RS49345	COG3842	ATPase activity
CYFUS_RS49350	COG1175	transmembrane transport
CYFUS_RS49365	COG0642	Histidine kinase
CYFUS_RS49370	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CYFUS_RS49385	COG0494	nUDIX hydrolase
CYFUS_RS49390	COG4251	negative regulation of phosphorylation
CYFUS_RS49395	COG1690	Belongs to the RtcB family
CYFUS_RS49440	COG0392	lysyltransferase activity
CYFUS_RS49460	COG0515	serine threonine protein kinase
CYFUS_RS49465	COG3311	Transcriptional regulator
CYFUS_RS49485	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CYFUS_RS49490	COG1104	cysteine desulfurase activity
CYFUS_RS49505	COG0028	Belongs to the TPP enzyme family
CYFUS_RS49550	COG0667	Aldo Keto reductase
CYFUS_RS49555	COG0667	Aldo Keto reductase
CYFUS_RS49565	COG0583	DNA-binding transcription factor activity
CYFUS_RS49630	COG2133	pyrroloquinoline quinone binding
CYFUS_RS49715	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CYFUS_RS49720	COG3708	Transcriptional regulator
CYFUS_RS49720	COG2207	Transcriptional regulator
CYFUS_RS49730	COG5507	3-demethylubiquinone-9 3-methyltransferase
CYFUS_RS49740	COG1320	monovalent cation:proton antiporter activity
CYFUS_RS49755	COG0651	ATP synthesis coupled electron transport
CYFUS_RS49760	COG1006	Multisubunit Na H antiporter MnhC subunit
CYFUS_RS49780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CYFUS_RS49785	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CYFUS_RS49790	COG1024	Enoyl-CoA hydratase
CYFUS_RS49795	COG3311	Transcriptional regulator
CYFUS_RS49800	COG1569	PIN domain
CYFUS_RS49835	COG3290	protein histidine kinase activity
CYFUS_RS49835	COG0840	transmembrane signaling receptor activity
CYFUS_RS49870	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CYFUS_RS49870	COG1845	cytochrome c oxidase, subunit III
CYFUS_RS49905	COG0437	4 iron, 4 sulfur cluster binding
CYFUS_RS49965	COG2070	2-Nitropropane dioxygenase
CYFUS_RS50015	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CYFUS_RS50020	COG5002	protein histidine kinase activity
CYFUS_RS50030	COG1012	belongs to the aldehyde dehydrogenase family
CYFUS_RS50075	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CYFUS_RS50095	COG1475	DNA binding
CYFUS_RS50100	COG1192	Involved in chromosome partitioning
CYFUS_RS50115	COG0357	Ribosomal RNA small subunit methyltransferase G
CYFUS_RS50120	COG0445	tRNA wobble uridine modification
CYFUS_RS50135	COG0612	Peptidase, M16
CYFUS_RS50170	COG0616	signal peptide processing
CYFUS_RS50180	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CYFUS_RS50195	COG0706	membrane insertase activity
CYFUS_RS50200	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CYFUS_RS50205	COG0594	ribonuclease P activity
CYFUS_RS50210	COG0230	Belongs to the bacterial ribosomal protein bL34 family