locus-tag	class	description
DCF50_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DCF50_RS00010	COG0592	DNA-directed DNA polymerase activity
DCF50_RS00025	COG0187	DNA topoisomerase II activity
DCF50_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DCF50_RS00035	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DCF50_RS00040	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DCF50_RS00115	COG1192	Involved in chromosome partitioning
DCF50_RS00120	COG1475	DNA binding
DCF50_RS00180	COG0551	DNA topoisomerase type I activity
DCF50_RS00180	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DCF50_RS00225	COG3843	relaxase mobilization nuclease domain protein
DCF50_RS00305	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DCF50_RS00315	COG1733	regulation of RNA biosynthetic process
DCF50_RS00325	COG1797	cobyrinic acid a,c-diamide synthase activity
DCF50_RS00340	COG2801	Transposase and inactivated derivatives
DCF50_RS00370	COG0569	domain protein
DCF50_RS00375	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DCF50_RS00385	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DCF50_RS00395	COG0456	acetyltransferase
DCF50_RS00400	COG1509	lysine 2,3-aminomutase activity
DCF50_RS00425	COG0641	radical SAM
DCF50_RS00520	COG5001	Diguanylate cyclase
DCF50_RS00610	COG1373	ATPase (AAA superfamily
DCF50_RS00640	COG1475	DNA binding
DCF50_RS00645	COG1192	Involved in chromosome partitioning
DCF50_RS00690	COG1192	Involved in chromosome partitioning
DCF50_RS00695	COG1475	DNA binding
DCF50_RS00735	COG3655	Transcriptional regulator
DCF50_RS00825	COG2200	EAL domain
DCF50_RS00825	COG2202	Pas domain
DCF50_RS00825	COG2199	diguanylate cyclase activity
DCF50_RS00925	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DCF50_RS00925	COG3608	succinylglutamate desuccinylase aspartoacylase
DCF50_RS00945	COG0640	Transcriptional regulator
DCF50_RS00950	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DCF50_RS00965	COG0640	Transcriptional regulator
DCF50_RS00975	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DCF50_RS00980	COG0640	Transcriptional regulator
DCF50_RS00985	COG0798	PFAM Bile acid sodium symporter
DCF50_RS01000	COG3608	succinylglutamate desuccinylase aspartoacylase
DCF50_RS01000	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DCF50_RS01020	COG0640	Transcriptional regulator
DCF50_RS01040	COG1595	DNA-templated transcription, initiation
DCF50_RS01050	COG0730	response to heat
DCF50_RS01055	COG3842	ATPase activity
DCF50_RS01060	COG4149	molybdate abc transporter
DCF50_RS01070	COG1910	domain protein
DCF50_RS01080	COG0640	Transcriptional regulator
DCF50_RS01085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DCF50_RS01100	COG0509	glycine decarboxylation via glycine cleavage system
DCF50_RS01120	COG0095	Lipoate-protein ligase
DCF50_RS01170	COG0095	Lipoate-protein ligase
DCF50_RS01185	COG2814	Major facilitator Superfamily
DCF50_RS01220	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DCF50_RS01235	COG3706	GGDEF domain
DCF50_RS01255	COG1396	sequence-specific DNA binding
DCF50_RS01275	COG0004	ammonium transporteR
DCF50_RS01305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DCF50_RS01310	COG1131	(ABC) transporter
DCF50_RS01315	COG1131	(ABC) transporter
DCF50_RS01320	COG0842	Transport permease protein
DCF50_RS01325	COG1309	transcriptional regulator
DCF50_RS01340	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DCF50_RS01345	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DCF50_RS01360	COG1013	pyruvate-flavodoxin oxidoreductase activity
DCF50_RS01360	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DCF50_RS01360	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DCF50_RS01360	COG0674	pyruvate-flavodoxin oxidoreductase activity
DCF50_RS01365	COG1982	Orn Lys Arg decarboxylase major
DCF50_RS01375	COG1774	PSP1 C-terminal conserved region
DCF50_RS01380	COG4467	Involved in initiation control of chromosome replication
DCF50_RS01385	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DCF50_RS01390	COG2002	toxin-antitoxin pair type II binding
DCF50_RS01395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DCF50_RS01395	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DCF50_RS01400	COG0084	hydrolase, TatD family'
DCF50_RS01410	COG5012	cobalamin binding
DCF50_RS01460	COG1151	hydroxylamine reductase activity
DCF50_RS01475	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DCF50_RS01480	COG3404	Formiminotransferase-cyclodeaminase
DCF50_RS01485	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DCF50_RS01490	COG2116	formate transmembrane transporter activity
DCF50_RS01505	COG2188	Transcriptional regulator
DCF50_RS01510	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DCF50_RS01515	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DCF50_RS01520	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DCF50_RS01545	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DCF50_RS01595	COG1802	Transcriptional regulator
DCF50_RS01600	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DCF50_RS01615	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DCF50_RS01630	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DCF50_RS01635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DCF50_RS01640	COG2002	toxin-antitoxin pair type II binding
DCF50_RS01645	COG3956	TIGRFAM MazG family protein
DCF50_RS01650	COG0776	regulation of translation
DCF50_RS01655	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DCF50_RS01690	COG0037	tRNA processing
DCF50_RS01695	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DCF50_RS01715	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DCF50_RS01725	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DCF50_RS01735	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DCF50_RS01745	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DCF50_RS01750	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DCF50_RS01765	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DCF50_RS01780	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DCF50_RS01800	COG0840	transmembrane signaling receptor activity
DCF50_RS01840	COG2197	response regulator
DCF50_RS01865	COG4980	gas vesicle protein
DCF50_RS01865	COG1674	ftsk spoiiie
DCF50_RS01870	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
DCF50_RS01875	COG1426	Protein conserved in bacteria
DCF50_RS01885	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DCF50_RS01890	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DCF50_RS01895	COG1546	Belongs to the CinA family
DCF50_RS01895	COG1058	Belongs to the CinA family
DCF50_RS01900	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DCF50_RS01905	COG2137	regulation of response to DNA damage stimulus
DCF50_RS01910	COG1418	mRNA catabolic process
DCF50_RS01920	COG1692	metallophosphoesterase
DCF50_RS01925	COG2359	stage V sporulation protein S
DCF50_RS01940	COG0436	Aminotransferase
DCF50_RS01955	COG0704	Plays a role in the regulation of phosphate uptake
DCF50_RS01975	COG0328	RNA-DNA hybrid ribonuclease activity
DCF50_RS01980	COG0045	succinate-CoA ligase (ADP-forming) activity
DCF50_RS01990	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DCF50_RS02000	COG0281	malic enzyme
DCF50_RS02005	COG3344	reverse transcriptase
DCF50_RS02015	COG2205	protein histidine kinase activity
DCF50_RS02020	COG0745	RESPONSE REGULATOR receiver
DCF50_RS02025	COG0531	amino acid
DCF50_RS02070	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DCF50_RS02075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DCF50_RS02085	COG2226	methyltransferase
DCF50_RS02090	COG0517	IMP dehydrogenase activity
DCF50_RS02095	COG5012	cobalamin binding
DCF50_RS02105	COG1739	Uncharacterized protein family UPF0029
DCF50_RS02125	COG3594	Acyltransferase
DCF50_RS02155	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DCF50_RS02165	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DCF50_RS02170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DCF50_RS02185	COG1164	Oligoendopeptidase f
DCF50_RS02195	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DCF50_RS02200	COG0454	-acetyltransferase
DCF50_RS02210	COG0739	heme binding
DCF50_RS02215	COG0322	excinuclease ABC activity
DCF50_RS02245	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DCF50_RS02250	COG2199	diguanylate cyclase activity
DCF50_RS02250	COG2203	Gaf domain
DCF50_RS02255	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DCF50_RS02260	COG1959	2 iron, 2 sulfur cluster binding
DCF50_RS02270	COG0822	iron-sulfur transferase activity
DCF50_RS02275	COG0482	sulfurtransferase activity
DCF50_RS02290	COG0628	permease
DCF50_RS02295	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DCF50_RS02315	COG3906	Belongs to the UPF0473 family
DCF50_RS02320	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DCF50_RS02325	COG0826	peptidase U32
DCF50_RS02355	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DCF50_RS02360	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DCF50_RS02370	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DCF50_RS02375	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DCF50_RS02400	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DCF50_RS02410	COG2165	general secretion pathway protein
DCF50_RS02425	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DCF50_RS02450	COG0006	proline dipeptidase activity
DCF50_RS02460	COG1388	LysM domain
DCF50_RS02460	COG3858	chitin binding
DCF50_RS02460	COG1388	LysM domain
DCF50_RS02460	COG3858	chitin binding
DCF50_RS02465	COG3854	ATPases associated with a variety of cellular activities
DCF50_RS02505	COG1302	Protein conserved in bacteria
DCF50_RS02520	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DCF50_RS02525	COG0543	2 iron, 2 sulfur cluster binding
DCF50_RS02530	COG0493	'glutamate synthase
DCF50_RS02530	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DCF50_RS02545	COG1570	exodeoxyribonuclease VII activity
DCF50_RS02550	COG1722	exodeoxyribonuclease VII activity
DCF50_RS02570	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DCF50_RS02575	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DCF50_RS02580	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DCF50_RS02585	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DCF50_RS02595	COG0497	DNA recombination
DCF50_RS02605	COG0750	zinc metalloprotease
DCF50_RS02615	COG0494	nUDIX hydrolase
DCF50_RS02620	COG1300	Membrane
DCF50_RS02640	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DCF50_RS02655	COG1686	Belongs to the peptidase S11 family
DCF50_RS02660	COG1191	sigma factor activity
DCF50_RS02665	COG2172	sigma factor antagonist activity
DCF50_RS02670	COG1366	Belongs to the anti-sigma-factor antagonist family
DCF50_RS02680	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DCF50_RS02690	COG0697	spore germination
DCF50_RS02740	COG1136	(ABC) transporter
DCF50_RS02740	COG0577	efflux transmembrane transporter activity
DCF50_RS02800	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DCF50_RS02800	COG0617	tRNA 3'-terminal CCA addition
DCF50_RS02800	COG3620	sequence-specific DNA binding
DCF50_RS02805	COG0180	Tryptophanyl-tRNA synthetase
DCF50_RS02815	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DCF50_RS02825	COG1295	ribonuclease BN
DCF50_RS02835	COG2323	membrane
DCF50_RS02850	COG0367	asparagine synthase
DCF50_RS02855	COG0512	Glutamine amidotransferase of anthranilate synthase
DCF50_RS02855	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DCF50_RS02865	COG0133	tryptophan synthase activity
DCF50_RS02870	COG0159	tryptophan synthase activity
DCF50_RS02875	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DCF50_RS02885	COG0135	phosphoribosylanthranilate isomerase activity
DCF50_RS02890	COG0706	membrane insertase activity
DCF50_RS02900	COG2949	membrane
DCF50_RS02910	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DCF50_RS02925	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DCF50_RS02935	COG0347	Belongs to the P(II) protein family
DCF50_RS02950	COG2059	Chromate
DCF50_RS02955	COG2059	Chromate
DCF50_RS02985	COG3344	reverse transcriptase
DCF50_RS02995	COG1597	lipid kinase activity
DCF50_RS03000	COG0484	heat shock protein binding
DCF50_RS03005	COG0542	response to heat
DCF50_RS03025	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DCF50_RS03025	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DCF50_RS03035	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DCF50_RS03035	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DCF50_RS03085	COG0640	Transcriptional regulator
DCF50_RS03090	COG0701	Predicted permease
DCF50_RS03100	COG4585	Histidine kinase
DCF50_RS03105	COG2197	response regulator
DCF50_RS03110	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DCF50_RS03120	COG3935	DnaD domain protein
DCF50_RS03125	COG1484	DNA-dependent DNA replication
DCF50_RS03140	COG5434	Belongs to the glycosyl hydrolase 28 family
DCF50_RS03140	COG4632	Exopolysaccharide biosynthesis protein
DCF50_RS03155	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
DCF50_RS03160	COG0668	transmembrane transport
DCF50_RS03165	COG1615	UPF0182 protein
DCF50_RS03170	COG0492	ferredoxin-NADP+ reductase activity
DCF50_RS03180	COG0705	Rhomboid family
DCF50_RS03180	COG0457	Tetratricopeptide repeat
DCF50_RS03185	COG0768	penicillin binding
DCF50_RS03205	COG1691	(AIR) carboxylase
DCF50_RS03230	COG1349	DNA-binding transcription factor activity
DCF50_RS03240	COG4942	peptidase
DCF50_RS03250	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DCF50_RS03255	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DCF50_RS03270	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DCF50_RS03275	COG2136	Putative SAM-dependent methyltransferase
DCF50_RS03275	COG2521	methyltransferase
DCF50_RS03290	COG0464	growth
DCF50_RS03295	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DCF50_RS03305	COG1181	Belongs to the D-alanine--D-alanine ligase family
DCF50_RS03345	COG1307	EDD domain protein, DegV family
DCF50_RS03355	COG0577	efflux transmembrane transporter activity
DCF50_RS03355	COG1136	(ABC) transporter
DCF50_RS03360	COG1136	(ABC) transporter
DCF50_RS03375	COG1278	Cold shock
DCF50_RS03390	COG0069	glutamate synthase activity
DCF50_RS03400	COG1962	PFAM Tetrahydromethanopterin S-methyltransferase MtrH subunit
DCF50_RS03405	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DCF50_RS03420	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DCF50_RS03425	COG1360	Flagellar Motor Protein
DCF50_RS03440	COG0551	DNA topoisomerase type I activity
DCF50_RS03440	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DCF50_RS03445	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DCF50_RS03445	COG0551	DNA topoisomerase type I activity
DCF50_RS03460	COG0784	Response regulator, receiver
DCF50_RS03460	COG0835	chemotaxis
DCF50_RS03475	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DCF50_RS03480	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DCF50_RS03485	COG0318	PFAM AMP-dependent synthetase and ligase
DCF50_RS03490	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DCF50_RS03510	COG0419	ATPase involved in DNA repair
DCF50_RS03515	COG0420	3'-5' exonuclease activity
DCF50_RS03520	COG0516	GMP reductase activity
DCF50_RS03520	COG0517	IMP dehydrogenase activity
DCF50_RS03525	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DCF50_RS03530	COG1132	(ABC) transporter
DCF50_RS03535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DCF50_RS03550	COG2197	response regulator
DCF50_RS03555	COG3850	Histidine kinase
DCF50_RS03580	COG3437	response regulator, receiver
DCF50_RS03590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DCF50_RS03595	COG2957	Belongs to the agmatine deiminase family
DCF50_RS03600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DCF50_RS03620	COG1194	a g-specific adenine glycosylase
DCF50_RS03635	COG4085	toxin activity
DCF50_RS03635	COG1525	nuclease
DCF50_RS03635	COG0737	Belongs to the 5'-nucleotidase family
DCF50_RS03640	COG2267	carboxylic ester hydrolase activity
DCF50_RS03645	COG0791	NLP P60 protein
DCF50_RS03655	COG3437	response regulator, receiver
DCF50_RS03670	COG2302	S4 RNA-binding domain
DCF50_RS03690	COG3344	reverse transcriptase
DCF50_RS03710	COG0488	(ABC) transporter
DCF50_RS03715	COG0488	(ABC) transporter
DCF50_RS03720	COG0596	Alpha beta hydrolase
DCF50_RS03735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DCF50_RS03740	COG3260	NADH ubiquinone oxidoreductase 20
DCF50_RS03745	COG3261	NADH dehydrogenase
DCF50_RS03745	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
DCF50_RS03750	COG0651	ATP synthesis coupled electron transport
DCF50_RS03765	COG0651	ATP synthesis coupled electron transport
DCF50_RS03770	COG1309	transcriptional regulator
DCF50_RS03780	COG0697	spore germination
DCF50_RS03795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DCF50_RS03805	COG2996	Protein conserved in bacteria
DCF50_RS03810	COG0288	reversible hydration of carbon dioxide
DCF50_RS03820	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DCF50_RS03825	COG3103	Sh3 type 3 domain protein
DCF50_RS03825	COG1388	LysM domain
DCF50_RS03825	COG0791	NLP P60 protein
DCF50_RS03840	COG1132	(ABC) transporter
DCF50_RS03865	COG0789	Transcriptional regulator
DCF50_RS03870	COG1592	Rubrerythrin
DCF50_RS03875	COG2814	Major facilitator Superfamily
DCF50_RS03890	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DCF50_RS03925	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
DCF50_RS03930	COG1492	cobalamin metabolic process
DCF50_RS03940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DCF50_RS03960	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DCF50_RS03975	COG1131	(ABC) transporter
DCF50_RS03990	COG0488	(ABC) transporter
DCF50_RS03995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DCF50_RS04000	COG2247	cell wall binding repeat
DCF50_RS04000	COG2385	sporulation resulting in formation of a cellular spore
DCF50_RS04005	COG1139	Iron-sulfur cluster binding protein
DCF50_RS04025	COG3459	Glycosyltransferase 36 associated
DCF50_RS04040	COG0613	PHP domain protein
DCF50_RS04085	COG0778	Nitroreductase
DCF50_RS04090	COG1368	sulfuric ester hydrolase activity
DCF50_RS04100	COG0409	Hydrogenase expression formation protein
DCF50_RS04105	COG0298	carbon dioxide binding
DCF50_RS04115	COG0375	protein maturation
DCF50_RS04125	COG0649	NAD binding
DCF50_RS04130	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DCF50_RS04135	COG3260	NADH ubiquinone oxidoreductase 20
DCF50_RS04140	COG0650	Formate hydrogenlyase subunit 4
DCF50_RS04145	COG2111	Na H antiporter
DCF50_RS04145	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DCF50_RS04150	COG0436	Aminotransferase
DCF50_RS04155	COG0577	efflux transmembrane transporter activity
DCF50_RS04160	COG1136	(ABC) transporter
DCF50_RS04165	COG0642	Histidine kinase
DCF50_RS04165	COG3850	Histidine kinase
DCF50_RS04170	COG0745	RESPONSE REGULATOR receiver
DCF50_RS04190	COG4221	oxidoreductase activity
DCF50_RS04200	COG1131	(ABC) transporter
DCF50_RS04210	COG3620	sequence-specific DNA binding
DCF50_RS04215	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DCF50_RS04220	COG2244	polysaccharide biosynthetic process
DCF50_RS04235	COG0302	gtp cyclohydrolase
DCF50_RS04240	COG0475	glutathione-regulated potassium exporter activity
DCF50_RS04245	COG0490	domain, Protein
DCF50_RS04250	COG4106	trans-aconitate 2-methyltransferase activity
DCF50_RS04275	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DCF50_RS04290	COG0205	6-phosphofructokinase activity
DCF50_RS04295	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DCF50_RS04300	COG0174	glutamine synthetase
DCF50_RS04325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DCF50_RS04340	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DCF50_RS04345	COG0745	RESPONSE REGULATOR receiver
DCF50_RS04350	COG1141	Ferredoxin
DCF50_RS04365	COG1199	ATP-dependent helicase activity
DCF50_RS04365	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DCF50_RS04375	COG2257	FlhB HrpN YscU SpaS Family
DCF50_RS04400	COG1937	Protein conserved in bacteria
DCF50_RS04405	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DCF50_RS04415	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DCF50_RS04420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DCF50_RS04425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DCF50_RS04430	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DCF50_RS04430	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DCF50_RS04450	COG0440	acetolactate synthase activity
DCF50_RS04455	COG0028	Belongs to the TPP enzyme family
DCF50_RS04460	COG1234	tRNA 3'-trailer cleavage
DCF50_RS04465	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DCF50_RS04470	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DCF50_RS04475	COG1862	Preprotein translocase
DCF50_RS04490	COG2385	sporulation resulting in formation of a cellular spore
DCF50_RS04500	COG0632	four-way junction helicase activity
DCF50_RS04515	COG0840	transmembrane signaling receptor activity
DCF50_RS04520	COG0697	spore germination
DCF50_RS04550	COG0437	4 iron, 4 sulfur cluster binding
DCF50_RS04555	COG0243	molybdopterin cofactor binding
DCF50_RS04555	COG3383	formate dehydrogenase (NAD+) activity
DCF50_RS04560	COG0243	molybdopterin cofactor binding
DCF50_RS04560	COG3383	formate dehydrogenase (NAD+) activity
DCF50_RS04565	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
DCF50_RS04570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DCF50_RS04580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DCF50_RS04600	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DCF50_RS04605	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DCF50_RS04615	COG1968	undecaprenyl-diphosphatase activity
DCF50_RS04635	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DCF50_RS04635	COG0515	serine threonine protein kinase
DCF50_RS04650	COG3344	reverse transcriptase
DCF50_RS04685	COG3344	reverse transcriptase
DCF50_RS04695	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DCF50_RS04705	COG0473	3-isopropylmalate dehydrogenase activity
DCF50_RS04710	COG0066	3-isopropylmalate dehydratase activity
DCF50_RS04715	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DCF50_RS04720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DCF50_RS04730	COG0440	acetolactate synthase activity
DCF50_RS04735	COG0028	Belongs to the TPP enzyme family
DCF50_RS04745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DCF50_RS04750	COG0460	homoserine dehydrogenase
DCF50_RS04765	COG0741	lytic transglycosylase activity
DCF50_RS04770	COG0237	dephospho-CoA kinase activity
DCF50_RS04775	COG1971	Probably functions as a manganese efflux pump
DCF50_RS04780	COG0488	(ABC) transporter
DCF50_RS04800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DCF50_RS04820	COG0674	pyruvate-flavodoxin oxidoreductase activity
DCF50_RS04820	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DCF50_RS04865	COG4109	DRTGG domain
DCF50_RS04875	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DCF50_RS04880	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DCF50_RS04890	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DCF50_RS04895	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DCF50_RS04905	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DCF50_RS04920	COG1522	sequence-specific DNA binding
DCF50_RS04925	COG0436	Aminotransferase
DCF50_RS04930	COG1773	rubredoxin
DCF50_RS04930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DCF50_RS04935	COG0617	tRNA 3'-terminal CCA addition
DCF50_RS04940	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DCF50_RS04950	COG0564	pseudouridine synthase activity
DCF50_RS04960	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DCF50_RS04975	COG1322	Protein conserved in bacteria
DCF50_RS05000	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DCF50_RS05005	COG1929	Belongs to the glycerate kinase type-1 family
DCF50_RS05030	COG2340	Cysteine-rich secretory protein family
DCF50_RS05045	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DCF50_RS05055	COG0142	geranyltranstransferase activity
DCF50_RS05060	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DCF50_RS05065	COG0805	protein transport
DCF50_RS05075	COG0247	lactate metabolic process
DCF50_RS05075	COG2181	nitrate reductase activity
DCF50_RS05080	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DCF50_RS05085	COG2086	electron transfer activity
DCF50_RS05090	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DCF50_RS05095	COG0840	transmembrane signaling receptor activity
DCF50_RS05105	COG4492	Belongs to the UPF0735 family
DCF50_RS05110	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DCF50_RS05120	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DCF50_RS05125	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DCF50_RS05130	COG1160	GTP binding
DCF50_RS05140	COG0772	Belongs to the SEDS family
DCF50_RS05145	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DCF50_RS05145	COG0539	negative regulation of cytoplasmic translation
DCF50_RS05180	COG2081	HI0933 family
DCF50_RS05190	COG2186	Transcriptional regulator
DCF50_RS05195	COG1187	pseudouridine synthase activity
DCF50_RS05200	COG0700	Nucleoside recognition
DCF50_RS05205	COG2715	membrane protein required for spore maturation
DCF50_RS05210	COG3874	Sporulation protein YtfJ
DCF50_RS05220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DCF50_RS05225	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DCF50_RS05230	COG0735	belongs to the Fur family
DCF50_RS05260	COG0723	plastoquinol--plastocyanin reductase activity
DCF50_RS05260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DCF50_RS05275	COG0235	Class ii aldolase
DCF50_RS05280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DCF50_RS05295	COG0697	spore germination
DCF50_RS05300	COG1522	sequence-specific DNA binding
DCF50_RS05305	COG0535	radical SAM domain protein
DCF50_RS05310	COG0535	radical SAM domain protein
DCF50_RS05335	COG2050	protein possibly involved in aromatic compounds catabolism
DCF50_RS05340	COG4948	Mandelate Racemase Muconate Lactonizing
DCF50_RS05345	COG0318	PFAM AMP-dependent synthetase and ligase
DCF50_RS05350	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DCF50_RS05355	COG0596	Alpha beta hydrolase
DCF50_RS05365	COG1169	isochorismate synthase
DCF50_RS05370	COG0538	isocitrate dehydrogenase activity
DCF50_RS05380	COG1162	GTPase activity
DCF50_RS05390	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DCF50_RS05395	COG0463	Glycosyl transferase, family 2
DCF50_RS05400	COG0463	Glycosyl transferase, family 2
DCF50_RS05400	COG0457	Tetratricopeptide repeat
DCF50_RS05410	COG0457	Tetratricopeptide repeat
DCF50_RS05410	COG0463	Glycosyl transferase, family 2
DCF50_RS05430	COG1970	mechanosensitive ion channel activity
DCF50_RS05445	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DCF50_RS05535	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DCF50_RS05545	COG3475	LICD family
DCF50_RS05585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DCF50_RS05600	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
DCF50_RS05600	COG0662	Cupin 2, conserved barrel domain protein
DCF50_RS05610	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DCF50_RS05615	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DCF50_RS05640	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DCF50_RS05670	COG2361	Protein of unknown function DUF86
DCF50_RS05735	COG1253	flavin adenine dinucleotide binding
DCF50_RS05740	COG1032	radical SAM domain protein
DCF50_RS05750	COG0318	PFAM AMP-dependent synthetase and ligase
DCF50_RS05755	COG2261	transglycosylase associated protein
DCF50_RS05760	COG1597	lipid kinase activity
DCF50_RS05775	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DCF50_RS05785	COG1151	hydroxylamine reductase activity
DCF50_RS05800	COG1113	amino acid transport
DCF50_RS05840	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DCF50_RS05845	COG1122	ATPase activity
DCF50_RS05875	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DCF50_RS05880	COG1733	regulation of RNA biosynthetic process
DCF50_RS05895	COG5012	cobalamin binding
DCF50_RS05915	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DCF50_RS05980	COG2226	methyltransferase
DCF50_RS05995	COG5012	cobalamin binding
DCF50_RS06010	COG1609	Transcriptional regulator
DCF50_RS06015	COG5012	cobalamin binding
DCF50_RS06025	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DCF50_RS06030	COG2135	peptidase activity
DCF50_RS06065	COG0583	DNA-binding transcription factor activity
DCF50_RS06075	COG5012	cobalamin binding
DCF50_RS06080	COG3275	phosphorelay sensor kinase activity
DCF50_RS06090	COG1477	protein flavinylation
DCF50_RS06140	COG4974	Belongs to the 'phage' integrase family
DCF50_RS06150	COG4974	Belongs to the 'phage' integrase family
DCF50_RS06155	COG3344	reverse transcriptase
DCF50_RS06160	COG3344	reverse transcriptase
DCF50_RS06165	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DCF50_RS06210	COG0583	DNA-binding transcription factor activity
DCF50_RS06230	COG0732	type I restriction modification DNA specificity domain
DCF50_RS06235	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DCF50_RS06245	COG2721	sulfolactate sulfo-lyase activity
DCF50_RS06250	COG2721	sulfolactate sulfo-lyase activity
DCF50_RS06275	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DCF50_RS06285	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DCF50_RS06325	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DCF50_RS06340	COG3547	Transposase (IS116 IS110 IS902 family)
DCF50_RS06360	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DCF50_RS06365	COG0778	Nitroreductase
DCF50_RS06405	COG1733	regulation of RNA biosynthetic process
DCF50_RS06470	COG3177	Filamentation induced by cAMP protein fic
DCF50_RS06575	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DCF50_RS06590	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DCF50_RS06615	COG2088	sporulation resulting in formation of a cellular spore
DCF50_RS06635	COG2002	toxin-antitoxin pair type II binding
DCF50_RS06665	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DCF50_RS06825	COG4974	Belongs to the 'phage' integrase family
DCF50_RS06880	COG4443	Transcriptional Coactivator p15 (PC4)
DCF50_RS06885	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DCF50_RS06895	COG0732	type I restriction modification DNA specificity domain
DCF50_RS06900	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DCF50_RS06910	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DCF50_RS06920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DCF50_RS06925	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DCF50_RS06930	COG0154	amidase activity
DCF50_RS06965	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DCF50_RS06965	COG0140	phosphoribosyl-ATP diphosphatase activity
DCF50_RS06985	COG0131	Imidazoleglycerol-phosphate dehydratase
DCF50_RS06990	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DCF50_RS06995	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DCF50_RS07000	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DCF50_RS07005	COG4496	protein, YerC YecD
DCF50_RS07010	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DCF50_RS07025	COG4864	UPF0365 protein
DCF50_RS07030	COG1030	water channel activity
DCF50_RS07040	COG2210	Belongs to the sulfur carrier protein TusA family
DCF50_RS07045	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DCF50_RS07065	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DCF50_RS07075	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DCF50_RS07085	COG0194	GDP metabolic process
DCF50_RS07095	COG1561	YicC-like family, N-terminal region
DCF50_RS07110	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DCF50_RS07120	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DCF50_RS07135	COG0284	orotidine-5'-phosphate decarboxylase activity
DCF50_RS07140	COG0167	dihydroorotate dehydrogenase activity
DCF50_RS07145	COG0543	2 iron, 2 sulfur cluster binding
DCF50_RS07150	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DCF50_RS07160	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DCF50_RS07175	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DCF50_RS07180	COG0564	pseudouridine synthase activity
DCF50_RS07190	COG4869	propanediol catabolic process
DCF50_RS07195	COG1799	cell septum assembly
DCF50_RS07200	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DCF50_RS07215	COG1873	PFAM PRC-barrel domain
DCF50_RS07220	COG1191	sigma factor activity
DCF50_RS07225	COG1191	sigma factor activity
DCF50_RS07255	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DCF50_RS07260	COG3856	small basic protein
DCF50_RS07270	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DCF50_RS07275	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DCF50_RS07280	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DCF50_RS07285	COG0772	Belongs to the SEDS family
DCF50_RS07290	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DCF50_RS07300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DCF50_RS07305	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DCF50_RS07310	COG0768	penicillin binding
DCF50_RS07325	COG2001	Belongs to the MraZ family
DCF50_RS07345	COG0735	belongs to the Fur family
DCF50_RS07355	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DCF50_RS07380	COG1316	TRANSCRIPTIONal
DCF50_RS07390	COG1921	L-seryl-tRNASec selenium transferase activity
DCF50_RS07400	COG4862	establishment of competence for transformation
DCF50_RS07415	COG0835	chemotaxis
DCF50_RS07420	COG4786	Flagellar basal body rod
DCF50_RS07425	COG1815	bacterial-type flagellum-dependent cell motility
DCF50_RS07430	COG4786	Flagellar basal body rod
DCF50_RS07440	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DCF50_RS07450	COG1191	sigma factor activity
DCF50_RS07480	COG1419	protein localization to endoplasmic reticulum
DCF50_RS07485	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DCF50_RS07490	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DCF50_RS07495	COG1684	flagellar biosynthetic protein fliR
DCF50_RS07500	COG1987	bacterial-type flagellum assembly
DCF50_RS07505	COG1338	Plays a role in the flagellum-specific transport system
DCF50_RS07515	COG2201	protein-glutamate methylesterase activity
DCF50_RS07520	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DCF50_RS07520	COG1776	CheC inhibitor of MCP methylation
DCF50_RS07525	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DCF50_RS07530	COG1580	Controls the rotational direction of flagella during chemotaxis
DCF50_RS07535	COG1582	Flagellar protein (FlbD)
DCF50_RS07545	COG1157	protein secretion by the type III secretion system
DCF50_RS07555	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DCF50_RS07560	COG1766	The M ring may be actively involved in energy transduction
DCF50_RS07575	COG2201	protein-glutamate methylesterase activity
DCF50_RS07585	COG0643	Histidine kinase
DCF50_RS07585	COG2198	Histidine kinase
DCF50_RS07595	COG1516	flagellar protein fliS
DCF50_RS07600	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DCF50_RS07610	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DCF50_RS07615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DCF50_RS07625	COG2826	transposase and inactivated derivatives, IS30 family
DCF50_RS07655	COG0028	Belongs to the TPP enzyme family
DCF50_RS07660	COG1088	dTDP-glucose 4,6-dehydratase activity
DCF50_RS07675	COG3958	Transketolase
DCF50_RS07680	COG3959	Transketolase, thiamine diphosphate binding domain
DCF50_RS07695	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DCF50_RS07700	COG0463	Glycosyl transferase, family 2
DCF50_RS07705	COG0463	Glycosyl transferase, family 2
DCF50_RS07710	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DCF50_RS07715	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
DCF50_RS07725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DCF50_RS07730	COG1256	bacterial-type flagellum assembly
DCF50_RS07730	COG4786	Flagellar basal body rod
DCF50_RS07755	COG4935	Belongs to the peptidase S8 family
DCF50_RS07755	COG2234	aminopeptidase activity
DCF50_RS07760	COG1728	Protein conserved in bacteria
DCF50_RS07765	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DCF50_RS07840	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DCF50_RS07840	COG0519	Catalyzes the synthesis of GMP from XMP
DCF50_RS07845	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DCF50_RS07860	COG0459	protein refolding
DCF50_RS07870	COG0347	Belongs to the P(II) protein family
DCF50_RS07875	COG0746	molybdenum cofactor guanylyltransferase activity
DCF50_RS07880	COG0446	pyridine nucleotide-disulphide oxidoreductase
DCF50_RS07890	COG1307	EDD domain protein, DegV family
DCF50_RS07895	COG1846	Transcriptional regulator
DCF50_RS07920	COG3383	formate dehydrogenase (NAD+) activity
DCF50_RS07925	COG3383	formate dehydrogenase (NAD+) activity
DCF50_RS07940	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DCF50_RS07945	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DCF50_RS07950	COG0456	acetyltransferase
DCF50_RS07955	COG1214	PFAM Peptidase M22, glycoprotease
DCF50_RS07960	COG0802	atpase or kinase
DCF50_RS07965	COG0804	urea catabolic process
DCF50_RS07970	COG2183	response to ionizing radiation
DCF50_RS07975	COG2337	Toxic component of a toxin-antitoxin (TA) module
DCF50_RS07985	COG3442	glutamine amidotransferase
DCF50_RS08010	COG0521	Mo-molybdopterin cofactor biosynthetic process
DCF50_RS08015	COG0315	cyclic pyranopterin monophosphate synthase activity
DCF50_RS08020	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DCF50_RS08025	COG1058	Belongs to the CinA family
DCF50_RS08025	COG1546	Belongs to the CinA family
DCF50_RS08030	COG0303	'Molybdopterin
DCF50_RS08035	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DCF50_RS08055	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DCF50_RS08060	COG1418	mRNA catabolic process
DCF50_RS08080	COG0493	'glutamate synthase
DCF50_RS08085	COG0067	glutamate synthase
DCF50_RS08085	COG0070	glutamate synthase
DCF50_RS08085	COG0069	glutamate synthase activity
DCF50_RS08090	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DCF50_RS08095	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DCF50_RS08100	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DCF50_RS08100	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DCF50_RS08105	COG0736	holo-[acyl-carrier-protein] synthase activity
DCF50_RS08110	COG3275	phosphorelay sensor kinase activity
DCF50_RS08120	COG1509	lysine 2,3-aminomutase activity
DCF50_RS08125	COG1242	4 iron, 4 sulfur cluster binding
DCF50_RS08130	COG0004	ammonium transporteR
DCF50_RS08145	COG2078	PFAM AMMECR1 domain protein
DCF50_RS08145	COG3885	ferrous iron binding
DCF50_RS08175	COG0544	peptidyl-prolyl cis-trans isomerase activity
DCF50_RS08180	COG0348	domain, Protein
DCF50_RS08180	COG3901	Regulator of nitric oxide reductase transcription
DCF50_RS08235	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
DCF50_RS08240	COG1533	DNA photolyase activity
DCF50_RS08260	COG1357	PFAM Pentapeptide repeats (8 copies)
DCF50_RS08275	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DCF50_RS08300	COG0789	Transcriptional regulator
DCF50_RS08345	COG3344	reverse transcriptase
DCF50_RS08370	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DCF50_RS08390	COG1410	methionine synthase
DCF50_RS08390	COG0646	methionine synthase
DCF50_RS08395	COG0745	RESPONSE REGULATOR receiver
DCF50_RS08400	COG2205	protein histidine kinase activity
DCF50_RS08405	COG0428	transporter
DCF50_RS08410	COG0326	Molecular chaperone. Has ATPase activity
DCF50_RS08425	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DCF50_RS08425	COG1918	ferrous iron import across plasma membrane
DCF50_RS08435	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DCF50_RS08440	COG1993	acr, cog1993
DCF50_RS08445	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DCF50_RS08450	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DCF50_RS08455	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DCF50_RS08470	COG1217	gtp-binding protein TYPA
DCF50_RS08485	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
DCF50_RS08500	COG0482	sulfurtransferase activity
DCF50_RS08505	COG2873	o-acetylhomoserine
DCF50_RS08510	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DCF50_RS08520	COG1959	2 iron, 2 sulfur cluster binding
DCF50_RS08525	COG1045	serine acetyltransferase
DCF50_RS08530	COG1606	tRNA processing
DCF50_RS08540	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DCF50_RS08550	COG2217	Heavy metal translocating P-type atpase
DCF50_RS08560	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
DCF50_RS08575	COG2873	o-acetylhomoserine
DCF50_RS08585	COG0564	pseudouridine synthase activity
DCF50_RS08590	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DCF50_RS08620	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DCF50_RS08625	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
DCF50_RS08635	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DCF50_RS08640	COG1694	Mazg nucleotide pyrophosphohydrolase
DCF50_RS08650	COG3437	response regulator, receiver
DCF50_RS08655	COG0657	acetylesterase activity
DCF50_RS08670	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DCF50_RS08675	COG1027	Aspartate ammonia-lyase
DCF50_RS08680	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DCF50_RS08720	COG0741	lytic transglycosylase activity
DCF50_RS08720	COG0739	heme binding
DCF50_RS08720	COG1196	nuclear chromosome segregation
DCF50_RS08750	COG3547	Transposase (IS116 IS110 IS902 family)
DCF50_RS08920	COG3177	Filamentation induced by cAMP protein fic
DCF50_RS08925	COG0582	viral genome integration into host DNA
DCF50_RS08935	COG2339	peptidase activity
DCF50_RS08940	COG2155	Conserved Protein
DCF50_RS08945	COG2814	Major facilitator Superfamily
DCF50_RS08950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DCF50_RS08955	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DCF50_RS08960	COG1876	peptidase activity
DCF50_RS08970	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DCF50_RS08985	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DCF50_RS08990	COG0306	phosphate transporter
DCF50_RS09005	COG1983	PspC domain protein
DCF50_RS09020	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
DCF50_RS09030	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
DCF50_RS09055	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DCF50_RS09065	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DCF50_RS09070	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DCF50_RS09075	COG1376	ErfK ybiS ycfS ynhG family protein
DCF50_RS09080	COG0745	RESPONSE REGULATOR receiver
DCF50_RS09085	COG3850	Histidine kinase
DCF50_RS09085	COG5002	protein histidine kinase activity
DCF50_RS09095	COG1131	(ABC) transporter
DCF50_RS09105	COG0860	N-Acetylmuramoyl-L-alanine amidase
DCF50_RS09120	COG0101	tRNA pseudouridine synthase activity
DCF50_RS09145	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DCF50_RS09150	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DCF50_RS09165	COG0201	protein transport
DCF50_RS09180	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DCF50_RS09200	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DCF50_RS09205	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DCF50_RS09210	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DCF50_RS09215	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DCF50_RS09225	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DCF50_RS09230	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DCF50_RS09235	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DCF50_RS09255	COG0088	Forms part of the polypeptide exit tunnel
DCF50_RS09260	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DCF50_RS09275	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DCF50_RS09290	COG1358	cellular component organization or biogenesis
DCF50_RS09295	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DCF50_RS09300	COG0085	RNA polymerase activity
DCF50_RS09310	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DCF50_RS09325	COG0250	Participates in transcription elongation, termination and antitermination
DCF50_RS09335	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DCF50_RS09350	COG3858	chitin binding
DCF50_RS09350	COG1388	LysM domain
DCF50_RS09360	COG2201	protein-glutamate methylesterase activity
DCF50_RS09390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DCF50_RS09395	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DCF50_RS09405	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DCF50_RS09415	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DCF50_RS09420	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DCF50_RS09420	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DCF50_RS09425	COG4956	integral membrane protein (PIN domain superfamily)
DCF50_RS09435	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DCF50_RS09440	COG0542	response to heat
DCF50_RS09445	COG3869	Catalyzes the specific phosphorylation of arginine residues in
DCF50_RS09450	COG3880	PFAM UvrB UvrC protein
DCF50_RS09465	COG2816	NAD+ diphosphatase activity
DCF50_RS09475	COG1331	Highly conserved protein containing a thioredoxin domain
DCF50_RS09495	COG0463	Glycosyl transferase, family 2
DCF50_RS09495	COG0457	Tetratricopeptide repeat
DCF50_RS09515	COG3546	catalase activity
DCF50_RS09525	COG0586	Pfam SNARE associated Golgi protein
DCF50_RS09575	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DCF50_RS09585	COG1193	negative regulation of DNA recombination
DCF50_RS09590	COG0826	peptidase U32
DCF50_RS09610	COG1090	epimerase
DCF50_RS09720	COG0475	glutathione-regulated potassium exporter activity
DCF50_RS09720	COG0569	domain protein
DCF50_RS09735	COG2848	UPF0210 protein
DCF50_RS09740	COG3830	Belongs to the UPF0237 family
DCF50_RS09745	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DCF50_RS09750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DCF50_RS09750	COG0072	phenylalanine-tRNA ligase activity
DCF50_RS09760	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DCF50_RS09765	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DCF50_RS09775	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DCF50_RS09790	COG3481	metal-dependent phosphohydrolase, HD sub domain
DCF50_RS09795	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DCF50_RS09810	COG3949	Membrane
DCF50_RS09815	COG0640	Transcriptional regulator
DCF50_RS09820	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
DCF50_RS09825	COG3706	GGDEF domain
DCF50_RS09835	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DCF50_RS09840	COG1982	Orn Lys Arg decarboxylase major
DCF50_RS09850	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DCF50_RS09880	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DCF50_RS09890	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
DCF50_RS09895	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
DCF50_RS09905	COG0347	Belongs to the P(II) protein family
DCF50_RS09910	COG0347	Belongs to the P(II) protein family
DCF50_RS09925	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DCF50_RS09930	COG2801	Transposase and inactivated derivatives
DCF50_RS09945	COG0523	cobalamin synthesis protein
DCF50_RS09955	COG5012	cobalamin binding
DCF50_RS09970	COG2188	Transcriptional regulator
DCF50_RS10030	COG1215	transferase activity, transferring glycosyl groups
DCF50_RS10040	COG2195	Cleaves the N-terminal amino acid of tripeptides
DCF50_RS10050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DCF50_RS10055	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DCF50_RS10060	COG1376	ErfK ybiS ycfS ynhG family protein
DCF50_RS10090	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DCF50_RS10095	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DCF50_RS10115	COG4969	Belongs to the N-Me-Phe pilin family
DCF50_RS10125	COG1191	sigma factor activity
DCF50_RS10160	COG1459	type II secretion system
DCF50_RS10240	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DCF50_RS10245	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DCF50_RS10250	COG0527	aspartate kinase activity
DCF50_RS10255	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DCF50_RS10260	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DCF50_RS10265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DCF50_RS10275	COG1873	PFAM PRC-barrel domain
DCF50_RS10285	COG0477	Major facilitator Superfamily
DCF50_RS10295	COG0612	Peptidase, M16
DCF50_RS10300	COG1686	Belongs to the peptidase S11 family
DCF50_RS10315	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DCF50_RS10320	COG0196	riboflavin kinase activity
DCF50_RS10325	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DCF50_RS10330	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DCF50_RS10340	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DCF50_RS10350	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DCF50_RS10355	COG0195	Participates in both transcription termination and antitermination
DCF50_RS10370	COG0442	prolyl-tRNA aminoacylation
DCF50_RS10375	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DCF50_RS10380	COG0750	zinc metalloprotease
DCF50_RS10385	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DCF50_RS10390	COG0628	permease
DCF50_RS10395	COG4589	Belongs to the CDS family
DCF50_RS10410	COG0233	cytoplasmic translational termination
DCF50_RS10415	COG0528	UMP kinase activity
DCF50_RS10450	COG4974	Belongs to the 'phage' integrase family
DCF50_RS10455	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DCF50_RS10460	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DCF50_RS10465	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DCF50_RS10465	COG0758	DNA mediated transformation
DCF50_RS10495	COG1476	TRANSCRIPTIONal
DCF50_RS10500	COG0004	ammonium transporteR
DCF50_RS10515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DCF50_RS10520	COG0791	NLP P60 protein
DCF50_RS10535	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DCF50_RS10545	COG3285	dna ligase
DCF50_RS10545	COG1793	dna ligase
DCF50_RS10550	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DCF50_RS10555	COG2217	Heavy metal translocating P-type atpase
DCF50_RS10575	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
DCF50_RS10585	COG0792	nuclease activity
DCF50_RS10595	COG1053	succinate dehydrogenase
DCF50_RS10610	COG0606	chelatase, subunit chli
DCF50_RS10620	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DCF50_RS10635	COG4752	Belongs to the RNA methyltransferase TrmD family
DCF50_RS10640	COG0336	Belongs to the RNA methyltransferase TrmD family
DCF50_RS10645	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DCF50_RS10660	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DCF50_RS10675	COG0402	S-adenosylhomocysteine deaminase activity
DCF50_RS10685	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DCF50_RS10690	COG0552	protein localization to endoplasmic reticulum
DCF50_RS10695	COG1196	nuclear chromosome segregation
DCF50_RS10700	COG0571	ribonuclease III activity
DCF50_RS10730	COG3314	Sporulation integral membrane protein YlbJ
DCF50_RS10740	COG0742	ribosomal rna small subunit methyltransferase
DCF50_RS10745	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
DCF50_RS10750	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DCF50_RS10755	COG1760	l-serine dehydratase
DCF50_RS10760	COG1760	l-serine dehydratase
DCF50_RS10765	COG1461	Dihydroxyacetone kinase
DCF50_RS10770	COG1302	Protein conserved in bacteria
DCF50_RS10780	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DCF50_RS10785	COG1162	GTPase activity
DCF50_RS10790	COG0515	serine threonine protein kinase
DCF50_RS10790	COG2815	serine threonine protein kinase
DCF50_RS10795	COG0768	penicillin binding
DCF50_RS10800	COG0772	Belongs to the SEDS family
DCF50_RS10805	COG0631	protein serine/threonine phosphatase activity
DCF50_RS10810	COG1716	ATPase activity
DCF50_RS10820	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DCF50_RS10825	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DCF50_RS10825	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DCF50_RS10830	COG2738	Putative neutral zinc metallopeptidase
DCF50_RS10835	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DCF50_RS10845	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DCF50_RS10850	COG2226	methyltransferase
DCF50_RS10855	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DCF50_RS10870	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DCF50_RS10880	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DCF50_RS10890	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DCF50_RS10895	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DCF50_RS10910	COG1131	(ABC) transporter
DCF50_RS10930	COG3547	Transposase (IS116 IS110 IS902 family)
DCF50_RS10940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DCF50_RS10950	COG0824	Thioesterase
DCF50_RS10965	COG0741	lytic transglycosylase activity
DCF50_RS10975	COG0077	Prephenate dehydratase
DCF50_RS10975	COG1605	Chorismate mutase
DCF50_RS10980	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DCF50_RS10985	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DCF50_RS10990	COG0287	Prephenate dehydrogenase
DCF50_RS10995	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DCF50_RS11005	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DCF50_RS11020	COG0735	belongs to the Fur family
DCF50_RS11025	COG1074	ATP-dependent DNA helicase activity
DCF50_RS11030	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DCF50_RS11050	COG0649	NAD binding
DCF50_RS11060	COG3260	NADH ubiquinone oxidoreductase 20
DCF50_RS11065	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DCF50_RS11070	COG2111	Na H antiporter
DCF50_RS11070	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DCF50_RS11075	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DCF50_RS11075	COG0493	'glutamate synthase
DCF50_RS11080	COG0543	2 iron, 2 sulfur cluster binding
DCF50_RS11085	COG1028	Short-chain dehydrogenase reductase Sdr
DCF50_RS11095	COG1671	Belongs to the UPF0178 family
DCF50_RS11100	COG0514	ATP-dependent DNA helicase (RecQ)
DCF50_RS11120	COG0488	(ABC) transporter
DCF50_RS11125	COG0719	Fe-S assembly protein
DCF50_RS11130	COG1136	(ABC) transporter
DCF50_RS11155	COG1994	Peptidase M50
DCF50_RS11185	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DCF50_RS11195	COG0531	amino acid
DCF50_RS11200	COG0745	RESPONSE REGULATOR receiver
DCF50_RS11205	COG2205	protein histidine kinase activity
DCF50_RS11210	COG0745	RESPONSE REGULATOR receiver
DCF50_RS11215	COG5002	protein histidine kinase activity
DCF50_RS11220	COG1136	(ABC) transporter
DCF50_RS11225	COG0577	efflux transmembrane transporter activity
DCF50_RS11230	COG1321	iron dependent repressor
DCF50_RS11235	COG1914	H( )-stimulated, divalent metal cation uptake system
DCF50_RS11245	COG0697	spore germination
DCF50_RS11255	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DCF50_RS11270	COG1329	Transcriptional regulator
DCF50_RS11275	COG1454	alcohol dehydrogenase
DCF50_RS11295	COG0515	serine threonine protein kinase
DCF50_RS11330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DCF50_RS11335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DCF50_RS11345	COG1007	ATP synthesis coupled electron transport
DCF50_RS11350	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DCF50_RS11355	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DCF50_RS11360	COG0713	ATP synthesis coupled electron transport
DCF50_RS11370	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DCF50_RS11375	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DCF50_RS11380	COG0649	NAD binding
DCF50_RS11385	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DCF50_RS11390	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DCF50_RS11395	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DCF50_RS11400	COG2033	superoxide reductase activity
DCF50_RS11405	COG0426	domain, Protein
DCF50_RS11420	COG1592	Rubrerythrin
DCF50_RS11425	COG0179	Fumarylacetoacetate (FAA) hydrolase
DCF50_RS11445	COG3852	Histidine kinase
DCF50_RS11455	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DCF50_RS11460	COG0840	transmembrane signaling receptor activity
DCF50_RS11490	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DCF50_RS11500	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DCF50_RS11505	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DCF50_RS11510	COG2201	protein-glutamate methylesterase activity
DCF50_RS11520	COG2201	protein-glutamate methylesterase activity
DCF50_RS11535	COG0835	chemotaxis
DCF50_RS11540	COG2198	Histidine kinase
DCF50_RS11540	COG0643	Histidine kinase
DCF50_RS11545	COG2201	protein-glutamate methylesterase activity
DCF50_RS11570	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DCF50_RS11575	COG1122	ATPase activity
DCF50_RS11580	COG1122	ATPase activity
DCF50_RS11600	COG0697	spore germination
DCF50_RS11615	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DCF50_RS11620	COG0505	Belongs to the CarA family
DCF50_RS11625	COG0463	Glycosyl transferase, family 2
DCF50_RS11645	COG1131	(ABC) transporter
DCF50_RS11650	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DCF50_RS11655	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DCF50_RS11660	COG0805	protein transport
DCF50_RS11670	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DCF50_RS11705	COG5012	cobalamin binding
DCF50_RS11735	COG3901	Regulator of nitric oxide reductase transcription
DCF50_RS11735	COG0348	domain, Protein
DCF50_RS11755	COG3901	Regulator of nitric oxide reductase transcription
DCF50_RS11755	COG0348	domain, Protein
DCF50_RS11785	COG4659	FMN binding
DCF50_RS11840	COG1714	RDD family
DCF50_RS11845	COG0616	signal peptide processing
DCF50_RS11850	COG4978	Transcriptional regulator
DCF50_RS11850	COG0789	Transcriptional regulator
DCF50_RS11875	COG2378	regulation of single-species biofilm formation
DCF50_RS11880	COG0564	pseudouridine synthase activity
DCF50_RS11885	COG4895	conserved protein (DUF2196)
DCF50_RS11895	COG1012	belongs to the aldehyde dehydrogenase family
DCF50_RS11920	COG5012	cobalamin binding
DCF50_RS11925	COG4753	response regulator
DCF50_RS11925	COG2207	Transcriptional regulator
DCF50_RS11935	COG5012	cobalamin binding
DCF50_RS11955	COG0523	cobalamin synthesis protein
DCF50_RS11990	COG0535	radical SAM domain protein
DCF50_RS11995	COG1592	Rubrerythrin
DCF50_RS12000	COG1053	succinate dehydrogenase
DCF50_RS12010	COG3794	PFAM blue (type 1) copper domain protein
DCF50_RS12025	COG3437	response regulator, receiver
DCF50_RS12025	COG3850	Histidine kinase
DCF50_RS12025	COG3437	response regulator, receiver
DCF50_RS12025	COG2205	protein histidine kinase activity
DCF50_RS12025	COG4999	Histidine kinase
DCF50_RS12025	COG2205	protein histidine kinase activity
DCF50_RS12025	COG4999	Histidine kinase
DCF50_RS12025	COG3850	Histidine kinase
DCF50_RS12045	COG5002	protein histidine kinase activity
DCF50_RS12045	COG2205	protein histidine kinase activity
DCF50_RS12045	COG0784	Response regulator, receiver
DCF50_RS12055	COG1131	(ABC) transporter
DCF50_RS12060	COG1725	Transcriptional regulator
DCF50_RS12075	COG5002	protein histidine kinase activity
DCF50_RS12125	COG3645	SOS response
DCF50_RS12130	COG2378	regulation of single-species biofilm formation
DCF50_RS12165	COG1061	Type III restriction enzyme res subunit
DCF50_RS12170	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DCF50_RS12230	COG0494	nUDIX hydrolase
DCF50_RS12250	COG0494	nUDIX hydrolase
DCF50_RS12265	COG3973	AAA domain
DCF50_RS12270	COG2247	cell wall binding repeat
DCF50_RS12270	COG0860	N-Acetylmuramoyl-L-alanine amidase
DCF50_RS12275	COG3344	reverse transcriptase
DCF50_RS12280	COG3344	reverse transcriptase
DCF50_RS12285	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DCF50_RS12285	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DCF50_RS12315	COG0778	Nitroreductase
DCF50_RS12320	COG0860	N-Acetylmuramoyl-L-alanine amidase
DCF50_RS12320	COG2247	cell wall binding repeat
DCF50_RS12330	COG1122	ATPase activity
DCF50_RS12350	COG1950	PFAM Membrane protein of
DCF50_RS12375	COG0393	Putative heavy-metal-binding
DCF50_RS12380	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DCF50_RS12395	COG0667	Aldo Keto reductase
DCF50_RS12425	COG3655	Transcriptional regulator
DCF50_RS12440	COG0484	heat shock protein binding
DCF50_RS12450	COG1131	(ABC) transporter
DCF50_RS12475	COG1316	TRANSCRIPTIONal
DCF50_RS12500	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DCF50_RS12520	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DCF50_RS12525	COG0358	DNA primase activity
DCF50_RS12530	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DCF50_RS12535	COG0574	Belongs to the PEP-utilizing enzyme family
DCF50_RS12535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DCF50_RS12545	COG0517	IMP dehydrogenase activity
DCF50_RS12550	COG0751	glycine-tRNA ligase activity
DCF50_RS12565	COG1381	Involved in DNA repair and RecF pathway recombination
DCF50_RS12575	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DCF50_RS12580	COG0295	cytidine deaminase activity
DCF50_RS12595	COG1480	7TM receptor with intracellular HD hydrolase
DCF50_RS12600	COG1702	phosphate starvation-inducible protein PhoH
DCF50_RS12615	COG1610	YqeY-like protein
DCF50_RS12625	COG0537	adenosine 5'-monophosphoramidase activity
DCF50_RS12635	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DCF50_RS12640	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DCF50_RS12645	COG2264	protein methyltransferase activity
DCF50_RS12680	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DCF50_RS12690	COG0728	peptidoglycan biosynthetic process
DCF50_RS12705	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DCF50_RS12730	COG0559	Belongs to the binding-protein-dependent transport system permease family
DCF50_RS12750	COG0840	transmembrane signaling receptor activity
DCF50_RS12755	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DCF50_RS12770	COG1596	polysaccharide export
DCF50_RS12770	COG1555	photosystem II stabilization
DCF50_RS12790	COG0799	negative regulation of ribosome biogenesis
DCF50_RS12800	COG0724	RNA recognition motif
DCF50_RS12810	COG1534	Rna-binding protein
DCF50_RS12830	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DCF50_RS12835	COG1530	ribonuclease E activity
DCF50_RS12855	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DCF50_RS12875	COG0772	Belongs to the SEDS family
DCF50_RS12885	COG2894	cell division
DCF50_RS12890	COG0768	penicillin binding
DCF50_RS12905	COG1077	Cell shape determining protein MreB Mrl
DCF50_RS12915	COG0424	maF-like protein
DCF50_RS12920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DCF50_RS12940	COG0285	dihydrofolate synthase activity
DCF50_RS12945	COG0525	valine-tRNA ligase activity
DCF50_RS12950	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DCF50_RS12955	COG2076	Multidrug Resistance protein
DCF50_RS12985	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DCF50_RS12990	COG1067	ATP-dependent peptidase activity
DCF50_RS12990	COG0470	DNA polymerase III
DCF50_RS13005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DCF50_RS13010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DCF50_RS13015	COG1120	ATPase activity
DCF50_RS13030	COG0544	peptidyl-prolyl cis-trans isomerase activity
DCF50_RS13055	COG1414	Transcriptional regulator
DCF50_RS13060	COG0860	N-Acetylmuramoyl-L-alanine amidase
DCF50_RS13060	COG2247	cell wall binding repeat
DCF50_RS13080	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DCF50_RS13095	COG4122	O-methyltransferase activity
DCF50_RS13110	COG1846	Transcriptional regulator
DCF50_RS13160	COG3773	Cell wall hydrolase
DCF50_RS13160	COG3409	Peptidoglycan-binding domain 1 protein
DCF50_RS13165	COG0793	Belongs to the peptidase S41A family
DCF50_RS13170	COG0628	permease
DCF50_RS13175	COG1309	transcriptional regulator
DCF50_RS13210	COG0860	N-Acetylmuramoyl-L-alanine amidase
DCF50_RS13210	COG2247	cell wall binding repeat
DCF50_RS13215	COG1404	Belongs to the peptidase S8 family
DCF50_RS13220	COG0577	efflux transmembrane transporter activity
DCF50_RS13225	COG1136	(ABC) transporter
DCF50_RS13230	COG1566	PFAM secretion protein HlyD family protein
DCF50_RS13250	COG0860	N-Acetylmuramoyl-L-alanine amidase
DCF50_RS13250	COG2247	cell wall binding repeat
DCF50_RS13255	COG1404	Belongs to the peptidase S8 family
DCF50_RS13260	COG2247	cell wall binding repeat
DCF50_RS13260	COG0860	N-Acetylmuramoyl-L-alanine amidase
DCF50_RS13275	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DCF50_RS13300	COG0438	transferase activity, transferring glycosyl groups
DCF50_RS13305	COG0438	transferase activity, transferring glycosyl groups
DCF50_RS13330	COG0673	inositol 2-dehydrogenase activity
DCF50_RS13340	COG1086	Polysaccharide biosynthesis protein
DCF50_RS13345	COG2247	cell wall binding repeat
DCF50_RS13345	COG0860	N-Acetylmuramoyl-L-alanine amidase
DCF50_RS13365	COG0640	Transcriptional regulator
DCF50_RS13375	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DCF50_RS13380	COG0740	serine-type endopeptidase activity
DCF50_RS13390	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DCF50_RS13395	COG0372	Belongs to the citrate synthase family
DCF50_RS13410	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
DCF50_RS13410	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
DCF50_RS13415	COG0825	malonyl-CoA metabolic process
DCF50_RS13420	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DCF50_RS13425	COG0439	Biotin carboxylase
DCF50_RS13430	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DCF50_RS13435	COG0511	ligase activity, forming carbon-carbon bonds
DCF50_RS13440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DCF50_RS13445	COG1028	Short-chain dehydrogenase reductase Sdr
DCF50_RS13450	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DCF50_RS13455	COG2070	2-Nitropropane dioxygenase
DCF50_RS13465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DCF50_RS13490	COG2205	protein histidine kinase activity
DCF50_RS13495	COG3437	response regulator, receiver
DCF50_RS13515	COG1309	transcriptional regulator
DCF50_RS13520	COG1511	domain protein
DCF50_RS13540	COG3850	Histidine kinase
DCF50_RS13540	COG5002	protein histidine kinase activity
DCF50_RS13545	COG0745	RESPONSE REGULATOR receiver
DCF50_RS13555	COG2186	Transcriptional regulator
DCF50_RS13580	COG0861	Integral membrane protein TerC family
DCF50_RS13590	COG0513	Belongs to the DEAD box helicase family
DCF50_RS13600	COG4149	molybdate abc transporter
DCF50_RS13605	COG0725	ABC transporter, periplasmic molybdate-binding protein
DCF50_RS13610	COG1910	domain protein
DCF50_RS13625	COG5002	protein histidine kinase activity
DCF50_RS13630	COG0745	RESPONSE REGULATOR receiver
DCF50_RS13640	COG0436	Aminotransferase
DCF50_RS13645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DCF50_RS13650	COG1122	ATPase activity
DCF50_RS13660	COG0310	cobalt ion transport
DCF50_RS13670	COG2199	diguanylate cyclase activity
DCF50_RS13670	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DCF50_RS13675	COG3852	Histidine kinase
DCF50_RS13680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DCF50_RS13690	COG5002	protein histidine kinase activity
DCF50_RS13700	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DCF50_RS13730	COG3852	Histidine kinase
DCF50_RS13735	COG3279	Response regulator of the LytR AlgR family
DCF50_RS13745	COG0598	Magnesium transport protein CorA
DCF50_RS13755	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DCF50_RS13765	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DCF50_RS13770	COG0602	queuosine metabolic process
DCF50_RS13775	COG0720	synthase
DCF50_RS13800	COG0704	Plays a role in the regulation of phosphate uptake
DCF50_RS13805	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DCF50_RS13810	COG0581	inorganic phosphate transmembrane transporter activity
DCF50_RS13815	COG0573	inorganic phosphate transmembrane transporter activity
DCF50_RS13820	COG5002	protein histidine kinase activity
DCF50_RS13825	COG0745	RESPONSE REGULATOR receiver
DCF50_RS13835	COG1199	ATP-dependent helicase activity
DCF50_RS13845	COG0372	Belongs to the citrate synthase family
DCF50_RS13850	COG2201	protein-glutamate methylesterase activity
DCF50_RS13855	COG2198	Histidine kinase
DCF50_RS13855	COG0643	Histidine kinase
DCF50_RS13860	COG0191	fructose-bisphosphate aldolase activity
DCF50_RS13890	COG2247	cell wall binding repeat
DCF50_RS13890	COG2385	sporulation resulting in formation of a cellular spore
DCF50_RS13920	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DCF50_RS13925	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DCF50_RS13930	COG0148	phosphopyruvate hydratase activity
DCF50_RS13940	COG0149	triose-phosphate isomerase activity
DCF50_RS13945	COG0126	phosphoglycerate kinase activity
DCF50_RS13950	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DCF50_RS13955	COG0569	domain protein
DCF50_RS13960	COG1283	sodium-dependent phosphate transmembrane transporter activity
DCF50_RS13970	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DCF50_RS13985	COG1032	radical SAM domain protein
DCF50_RS13990	COG0561	phosphatase activity
DCF50_RS13995	COG4585	Histidine kinase
DCF50_RS14000	COG2197	response regulator
DCF50_RS14005	COG1131	(ABC) transporter
DCF50_RS14020	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DCF50_RS14025	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DCF50_RS14030	COG0556	nucleotide-excision repair
DCF50_RS14040	COG0793	Belongs to the peptidase S41A family
DCF50_RS14045	COG4942	peptidase
DCF50_RS14050	COG2177	Part of the ABC transporter FtsEX involved in
DCF50_RS14055	COG2884	Cell division ATP-binding protein ftsE
DCF50_RS14060	COG3958	Transketolase
DCF50_RS14065	COG3959	Transketolase, thiamine diphosphate binding domain
DCF50_RS14070	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DCF50_RS14075	COG0653	protein targeting
DCF50_RS14080	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DCF50_RS14085	COG1040	competence protein
DCF50_RS14090	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DCF50_RS14105	COG0438	transferase activity, transferring glycosyl groups
DCF50_RS14115	COG1077	Cell shape determining protein MreB Mrl
DCF50_RS14120	COG1609	Transcriptional regulator
DCF50_RS14130	COG2385	sporulation resulting in formation of a cellular spore
DCF50_RS14135	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DCF50_RS14155	COG4974	Belongs to the 'phage' integrase family
DCF50_RS14165	COG4974	Belongs to the 'phage' integrase family
DCF50_RS14170	COG3344	reverse transcriptase
DCF50_RS14180	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DCF50_RS14205	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DCF50_RS14210	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DCF50_RS14215	COG0356	it plays a direct role in the translocation of protons across the membrane
DCF50_RS14230	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DCF50_RS14240	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DCF50_RS14245	COG4475	Protein of unknown function (DUF436)
DCF50_RS14250	COG0698	ribose 5-phosphate isomerase
DCF50_RS14260	COG1971	Probably functions as a manganese efflux pump
DCF50_RS14265	COG0009	L-threonylcarbamoyladenylate synthase
DCF50_RS14270	COG2890	protein-(glutamine-N5) methyltransferase activity
DCF50_RS14275	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DCF50_RS14280	COG3872	metal-dependent enzyme
DCF50_RS14290	COG1494	fructose-1,6-bisphosphatase
DCF50_RS14305	COG2204	response regulator
DCF50_RS14320	COG0504	CTP synthase activity
DCF50_RS14330	COG2959	enzyme of heme biosynthesis
DCF50_RS14340	COG0277	FAD linked oxidase domain protein
DCF50_RS14350	COG0017	Asparaginyl-tRNA synthetase
DCF50_RS14360	COG0116	Belongs to the methyltransferase superfamily
DCF50_RS14375	COG3547	Transposase (IS116 IS110 IS902 family)
DCF50_RS14390	COG1408	metallophosphoesterase
DCF50_RS14395	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DCF50_RS14400	COG1575	Belongs to the MenA family. Type 1 subfamily
DCF50_RS14410	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
DCF50_RS14415	COG0653	protein targeting
DCF50_RS14425	COG3290	protein histidine kinase activity
DCF50_RS14425	COG0840	transmembrane signaling receptor activity
DCF50_RS14430	COG2207	Transcriptional regulator
DCF50_RS14455	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DCF50_RS14460	COG0113	porphobilinogen synthase activity
DCF50_RS14470	COG0181	hydroxymethylbilane synthase activity
DCF50_RS14485	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DCF50_RS14505	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DCF50_RS14510	COG1122	ATPase activity
DCF50_RS14525	COG0310	cobalt ion transport
DCF50_RS14545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DCF50_RS14550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DCF50_RS14555	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DCF50_RS14610	COG0305	Participates in initiation and elongation during chromosome replication
DCF50_RS14615	COG0470	DNA polymerase III
DCF50_RS14615	COG1067	ATP-dependent peptidase activity
DCF50_RS14635	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DCF50_RS14640	COG0629	single-stranded DNA binding
DCF50_RS14650	COG0012	GTP binding
DCF50_RS14685	COG1475	DNA binding
DCF50_RS14690	COG1192	Involved in chromosome partitioning
DCF50_RS14695	COG0357	Ribosomal RNA small subunit methyltransferase G
DCF50_RS14700	COG0445	tRNA wobble uridine modification
DCF50_RS14705	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DCF50_RS14710	COG1847	R3H domain protein
DCF50_RS14715	COG0706	membrane insertase activity
DCF50_RS14720	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DCF50_RS14725	COG0594	ribonuclease P activity
DCF50_RS14765	COG2088	sporulation resulting in formation of a cellular spore