locus-tag	class	description
BTF_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BTF_RS00020	COG0187	DNA topoisomerase II activity
BTF_RS00025	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BTF_RS00045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTF_RS00130	COG0569	domain protein
BTF_RS00140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTF_RS00145	COG0569	domain protein
BTF_RS00155	COG0306	phosphate transporter
BTF_RS00170	COG0543	2 iron, 2 sulfur cluster binding
BTF_RS00175	COG0493	'glutamate synthase
BTF_RS00190	COG2226	methyltransferase
BTF_RS00210	COG0012	GTP binding
BTF_RS00250	COG1979	alcohol dehydrogenase
BTF_RS00265	COG0542	response to heat
BTF_RS00270	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BTF_RS00335	COG1307	EDD domain protein, DegV family
BTF_RS00340	COG1704	LemA family
BTF_RS00350	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BTF_RS00365	COG0437	4 iron, 4 sulfur cluster binding
BTF_RS00390	COG0693	protein deglycase activity
BTF_RS00395	COG0511	ligase activity, forming carbon-carbon bonds
BTF_RS00395	COG5016	pyruvate
BTF_RS00400	COG0439	Biotin carboxylase
BTF_RS00410	COG0493	'glutamate synthase
BTF_RS00415	COG1063	alcohol dehydrogenase
BTF_RS00435	COG0432	Pfam Uncharacterised protein family UPF0047
BTF_RS00440	COG0745	RESPONSE REGULATOR receiver
BTF_RS00445	COG2204	response regulator
BTF_RS00465	COG4968	Prepilin-type N-terminal cleavage methylation domain
BTF_RS00470	COG0745	RESPONSE REGULATOR receiver
BTF_RS00475	COG5002	protein histidine kinase activity
BTF_RS00480	COG1803	Methylglyoxal synthase
BTF_RS00485	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BTF_RS00490	COG0573	inorganic phosphate transmembrane transporter activity
BTF_RS00495	COG0581	inorganic phosphate transmembrane transporter activity
BTF_RS00505	COG0704	Plays a role in the regulation of phosphate uptake
BTF_RS00540	COG2267	carboxylic ester hydrolase activity
BTF_RS00580	COG0745	RESPONSE REGULATOR receiver
BTF_RS00585	COG5002	protein histidine kinase activity
BTF_RS00610	COG0513	Belongs to the DEAD box helicase family
BTF_RS00625	COG5557	Pfam Polysulphide reductase, NrfD
BTF_RS00635	COG0742	ribosomal rna small subunit methyltransferase
BTF_RS00645	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BTF_RS00665	COG2081	HI0933 family
BTF_RS00670	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BTF_RS00670	COG0456	acetyltransferase
BTF_RS00700	COG0363	glucosamine-6-phosphate deaminase activity
BTF_RS00705	COG0667	Aldo Keto reductase
BTF_RS00735	COG0488	(ABC) transporter
BTF_RS00745	COG2081	HI0933 family
BTF_RS00940	COG4824	toxin secretion phage lysis holin
BTF_RS01015	COG4695	Portal protein
BTF_RS01020	COG1802	Transcriptional regulator
BTF_RS01020	COG4626	Terminase
BTF_RS01055	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BTF_RS01110	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTF_RS01110	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTF_RS01170	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BTF_RS01180	COG1396	sequence-specific DNA binding
BTF_RS01205	COG0484	heat shock protein binding
BTF_RS01290	COG1404	Belongs to the peptidase S8 family
BTF_RS01330	COG4974	Belongs to the 'phage' integrase family
BTF_RS01365	COG3177	Filamentation induced by cAMP protein fic
BTF_RS01420	COG0210	DNA helicase
BTF_RS01475	COG1752	Esterase of the alpha-beta hydrolase superfamily
BTF_RS01505	COG0123	including yeast histone deacetylase and acetoin utilization protein
BTF_RS01515	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTF_RS01520	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTF_RS01525	COG0617	tRNA 3'-terminal CCA addition
BTF_RS01535	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BTF_RS01565	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BTF_RS01585	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BTF_RS01590	COG1610	YqeY-like protein
BTF_RS01640	COG0793	Belongs to the peptidase S41A family
BTF_RS01655	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BTF_RS01675	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BTF_RS01680	COG4589	Belongs to the CDS family
BTF_RS01700	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BTF_RS01710	COG0047	phosphoribosylformylglycinamidine synthase activity
BTF_RS01715	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BTF_RS01740	COG0516	GMP reductase activity
BTF_RS01745	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BTF_RS01760	COG0142	geranyltranstransferase activity
BTF_RS01765	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BTF_RS01775	COG0799	negative regulation of ribosome biogenesis
BTF_RS01785	COG1214	PFAM Peptidase M22, glycoprotease
BTF_RS01790	COG0802	atpase or kinase
BTF_RS01795	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BTF_RS01805	COG2226	methyltransferase
BTF_RS01810	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BTF_RS01850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTF_RS01855	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BTF_RS01855	COG0617	tRNA 3'-terminal CCA addition
BTF_RS01855	COG3620	sequence-specific DNA binding
BTF_RS01865	COG0842	Transport permease protein
BTF_RS01880	COG1597	lipid kinase activity
BTF_RS01895	COG1126	abc transporter atp-binding protein
BTF_RS01900	COG0765	amino acid transport
BTF_RS01920	COG0598	Magnesium transport protein CorA
BTF_RS01940	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BTF_RS01940	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BTF_RS01950	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BTF_RS01980	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BTF_RS01990	COG1573	uracil-dna glycosylase
BTF_RS01995	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BTF_RS02000	COG1674	ftsk spoiiie
BTF_RS02030	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BTF_RS02035	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BTF_RS02045	COG0066	3-isopropylmalate dehydratase activity
BTF_RS02050	COG0473	3-isopropylmalate dehydrogenase activity
BTF_RS02075	COG0537	adenosine 5'-monophosphoramidase activity
BTF_RS02080	COG0494	nUDIX hydrolase
BTF_RS02085	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BTF_RS02105	COG1605	Chorismate mutase
BTF_RS02105	COG0077	Prephenate dehydratase
BTF_RS02140	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BTF_RS02270	COG0024	Methionine aminopeptidase
BTF_RS02345	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BTF_RS02365	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BTF_RS02380	COG1131	(ABC) transporter
BTF_RS02410	COG0312	modulator of DNA gyrase
BTF_RS02415	COG0312	modulator of DNA gyrase
BTF_RS02420	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BTF_RS02435	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BTF_RS02445	COG1011	Hydrolase
BTF_RS02450	COG0019	diaminopimelate decarboxylase activity
BTF_RS02455	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BTF_RS02460	COG1774	PSP1 C-terminal conserved region
BTF_RS02480	COG0305	Participates in initiation and elongation during chromosome replication
BTF_RS02490	COG0492	ferredoxin-NADP+ reductase activity
BTF_RS02500	COG1924	4 iron, 4 sulfur cluster binding
BTF_RS02525	COG0419	ATPase involved in DNA repair
BTF_RS02530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BTF_RS02535	COG0358	DNA primase activity
BTF_RS02540	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BTF_RS02545	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BTF_RS02545	COG0574	Belongs to the PEP-utilizing enzyme family
BTF_RS02560	COG0356	it plays a direct role in the translocation of protons across the membrane
BTF_RS02620	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BTF_RS02630	COG2003	Belongs to the UPF0758 family
BTF_RS02635	COG0747	negative chemotaxis
BTF_RS02680	COG0598	Magnesium transport protein CorA
BTF_RS02690	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BTF_RS02695	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BTF_RS02725	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BTF_RS02770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BTF_RS02805	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BTF_RS02810	COG0456	acetyltransferase
BTF_RS02825	COG2226	methyltransferase
BTF_RS02835	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
BTF_RS02840	COG3259	Nickel-dependent hydrogenase
BTF_RS02855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTF_RS02860	COG0785	Cytochrome C biogenesis protein
BTF_RS02885	COG3437	response regulator, receiver
BTF_RS02905	COG1509	lysine 2,3-aminomutase activity
BTF_RS02910	COG1181	Belongs to the D-alanine--D-alanine ligase family
BTF_RS02915	COG0735	belongs to the Fur family
BTF_RS02920	COG0803	Belongs to the bacterial solute-binding protein 9 family
BTF_RS02920	COG3443	Belongs to the bacterial solute-binding protein 9 family
BTF_RS02925	COG1121	(ABC) transporter
BTF_RS02930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BTF_RS02940	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BTF_RS02960	COG0589	response to stress
BTF_RS02970	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BTF_RS02975	COG0698	ribose 5-phosphate isomerase
BTF_RS02980	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BTF_RS02985	COG0778	Nitroreductase
BTF_RS02990	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BTF_RS03000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTF_RS03005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTF_RS03010	COG1120	ATPase activity
BTF_RS03025	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BTF_RS03040	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BTF_RS03045	COG0406	alpha-ribazole phosphatase activity
BTF_RS03050	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
BTF_RS03055	COG3118	belongs to the thioredoxin family
BTF_RS03065	COG2197	response regulator
BTF_RS03130	COG0740	serine-type endopeptidase activity
BTF_RS03150	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BTF_RS03155	COG0006	proline dipeptidase activity
BTF_RS03160	COG4974	Belongs to the 'phage' integrase family
BTF_RS03165	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BTF_RS03170	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BTF_RS03170	COG0758	DNA mediated transformation
BTF_RS03185	COG0475	glutathione-regulated potassium exporter activity
BTF_RS03205	COG0674	pyruvate-flavodoxin oxidoreductase activity
BTF_RS03210	COG1013	pyruvate-flavodoxin oxidoreductase activity
BTF_RS03235	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BTF_RS03240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTF_RS03265	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BTF_RS03280	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BTF_RS03295	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
BTF_RS03300	COG0126	phosphoglycerate kinase activity
BTF_RS03320	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BTF_RS03335	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BTF_RS03365	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BTF_RS03400	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BTF_RS03415	COG0517	IMP dehydrogenase activity
BTF_RS03415	COG1994	Peptidase M50
BTF_RS03420	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BTF_RS03425	COG0492	ferredoxin-NADP+ reductase activity
BTF_RS03440	COG0517	IMP dehydrogenase activity
BTF_RS03440	COG1994	Peptidase M50
BTF_RS03455	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BTF_RS03460	COG3854	ATPases associated with a variety of cellular activities
BTF_RS03485	COG0352	thiamine-phosphate diphosphorylase activity
BTF_RS03495	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BTF_RS03500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTF_RS03510	COG0423	glycine-tRNA ligase activity
BTF_RS03515	COG0420	3'-5' exonuclease activity
BTF_RS03520	COG1187	pseudouridine synthase activity
BTF_RS03535	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BTF_RS03545	COG1131	(ABC) transporter
BTF_RS03595	COG1695	Transcriptional regulator
BTF_RS03630	COG1131	(ABC) transporter
BTF_RS03635	COG0842	Transport permease protein
BTF_RS03640	COG0396	ATPase activity
BTF_RS03645	COG0719	Fe-S assembly protein
BTF_RS03650	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BTF_RS03690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BTF_RS03700	COG0066	3-isopropylmalate dehydratase activity
BTF_RS03705	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BTF_RS03710	COG1285	pathogenesis
BTF_RS03715	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BTF_RS03730	COG0028	Belongs to the TPP enzyme family
BTF_RS03740	COG0009	L-threonylcarbamoyladenylate synthase
BTF_RS03755	COG0151	Belongs to the GarS family
BTF_RS03760	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BTF_RS03765	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BTF_RS03770	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BTF_RS03790	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BTF_RS03805	COG0330	HflC and HflK could
BTF_RS03820	COG4152	abc transporter atp-binding protein
BTF_RS03850	COG1136	(ABC) transporter
BTF_RS03850	COG0577	efflux transmembrane transporter activity
BTF_RS03855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BTF_RS03865	COG2111	Na H antiporter
BTF_RS03865	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BTF_RS03870	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BTF_RS03875	COG3260	NADH ubiquinone oxidoreductase 20
BTF_RS03895	COG0493	'glutamate synthase
BTF_RS03895	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BTF_RS03905	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTF_RS03910	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BTF_RS03915	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BTF_RS03920	COG1846	Transcriptional regulator
BTF_RS03925	COG1033	growth of symbiont in host cell
BTF_RS03925	COG2409	Drug exporters of the RND superfamily
BTF_RS03940	COG2963	transposase activity
BTF_RS03945	COG2801	Transposase and inactivated derivatives
BTF_RS03975	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BTF_RS04045	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTF_RS04070	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTF_RS04085	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BTF_RS04090	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTF_RS04100	COG0084	hydrolase, TatD family'
BTF_RS04105	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BTF_RS04130	COG0318	PFAM AMP-dependent synthetase and ligase
BTF_RS04160	COG0318	PFAM AMP-dependent synthetase and ligase
BTF_RS04185	COG0822	iron-sulfur transferase activity
BTF_RS04195	COG2217	Heavy metal translocating P-type atpase
BTF_RS04200	COG0071	Belongs to the small heat shock protein (HSP20) family
BTF_RS04315	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BTF_RS04340	COG1598	PFAM Uncharacterised protein family UPF0150
BTF_RS04495	COG0107	imidazoleglycerol-phosphate synthase activity
BTF_RS04505	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BTF_RS04510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BTF_RS04515	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BTF_RS04515	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BTF_RS04530	COG1111	helicase
BTF_RS04530	COG1205	dead DEAH box helicase
BTF_RS04555	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BTF_RS04580	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BTF_RS04585	COG0438	transferase activity, transferring glycosyl groups
BTF_RS04590	COG1260	myo-inositol-1-phosphate synthase
BTF_RS04615	COG0195	Participates in both transcription termination and antitermination
BTF_RS04620	COG0606	chelatase, subunit chli
BTF_RS04660	COG0250	Participates in transcription elongation, termination and antitermination
BTF_RS04665	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BTF_RS04725	COG2211	Major facilitator Superfamily
BTF_RS04760	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BTF_RS04835	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BTF_RS04840	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BTF_RS04845	COG1307	EDD domain protein, DegV family
BTF_RS04850	COG0318	PFAM AMP-dependent synthetase and ligase
BTF_RS04855	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
BTF_RS04860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTF_RS04865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTF_RS04875	COG1847	R3H domain protein
BTF_RS04880	COG0706	membrane insertase activity
BTF_RS04900	COG0629	single-stranded DNA binding
BTF_RS04920	COG0251	oxidation-reduction process
BTF_RS04935	COG0497	DNA recombination
BTF_RS04940	COG0697	spore germination
BTF_RS04955	COG2205	protein histidine kinase activity
BTF_RS04960	COG4608	Belongs to the ABC transporter superfamily
BTF_RS04965	COG0444	Belongs to the ABC transporter superfamily
BTF_RS04970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTF_RS04975	COG0601	transmembrane transport
BTF_RS04980	COG4166	transmembrane transport
BTF_RS04985	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BTF_RS04990	COG2197	response regulator
BTF_RS05000	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BTF_RS05020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BTF_RS05020	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BTF_RS05025	COG0174	glutamine synthetase
BTF_RS05035	COG0004	ammonium transporteR
BTF_RS05040	COG0745	RESPONSE REGULATOR receiver
BTF_RS05050	COG0069	glutamate synthase activity
BTF_RS05060	COG0067	glutamate synthase
BTF_RS05065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BTF_RS05075	COG0493	'glutamate synthase
BTF_RS05075	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BTF_RS05105	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BTF_RS05110	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BTF_RS05115	COG0726	polysaccharide deacetylase
BTF_RS05135	COG2197	response regulator
BTF_RS05140	COG0045	succinate-CoA ligase (ADP-forming) activity
BTF_RS05140	COG1042	CoA-binding domain protein
BTF_RS05140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTF_RS05150	COG0735	belongs to the Fur family
BTF_RS05175	COG1132	(ABC) transporter
BTF_RS05225	COG1268	BioY protein
BTF_RS05245	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BTF_RS05245	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BTF_RS05255	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTF_RS05255	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTF_RS05260	COG2968	Membrane
BTF_RS05265	COG0681	Belongs to the peptidase S26 family
BTF_RS05270	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BTF_RS05280	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BTF_RS05285	COG0210	DNA helicase
BTF_RS05305	COG0505	Belongs to the CarA family
BTF_RS05310	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BTF_RS05315	COG0543	2 iron, 2 sulfur cluster binding
BTF_RS05325	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BTF_RS05330	COG0460	homoserine dehydrogenase
BTF_RS05340	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BTF_RS05345	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTF_RS05355	COG2890	protein-(glutamine-N5) methyltransferase activity
BTF_RS05360	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BTF_RS05375	COG4974	Belongs to the 'phage' integrase family
BTF_RS05390	COG0561	phosphatase activity
BTF_RS05410	COG0179	Fumarylacetoacetate (FAA) hydrolase
BTF_RS05415	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BTF_RS05420	COG1980	fructose-bisphosphate aldolase activity
BTF_RS05425	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BTF_RS05430	COG0592	DNA-directed DNA polymerase activity
BTF_RS05440	COG2801	Transposase and inactivated derivatives
BTF_RS05445	COG2963	transposase activity
BTF_RS05490	COG0788	formyltetrahydrofolate deformylase activity
BTF_RS05500	COG0798	PFAM Bile acid sodium symporter
BTF_RS05510	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BTF_RS05515	COG0655	NAD(P)H dehydrogenase (quinone) activity
BTF_RS05530	COG0640	Transcriptional regulator
BTF_RS05575	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BTF_RS05595	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BTF_RS05605	COG1307	EDD domain protein, DegV family
BTF_RS05610	COG1307	EDD domain protein, DegV family
BTF_RS05615	COG1307	EDD domain protein, DegV family
BTF_RS05620	COG1307	EDD domain protein, DegV family
BTF_RS05625	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BTF_RS05630	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BTF_RS05645	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BTF_RS05665	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BTF_RS05670	COG1028	Short-chain dehydrogenase reductase Sdr
BTF_RS05685	COG1032	radical SAM domain protein
BTF_RS05690	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BTF_RS05710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTF_RS05715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTF_RS05720	COG0789	Transcriptional regulator
BTF_RS05740	COG1546	Belongs to the CinA family
BTF_RS05740	COG1058	Belongs to the CinA family
BTF_RS05760	COG0745	RESPONSE REGULATOR receiver
BTF_RS05775	COG1217	gtp-binding protein TYPA
BTF_RS05795	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BTF_RS05815	COG3422	double-strand break repair
BTF_RS05825	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BTF_RS05840	COG2078	PFAM AMMECR1 domain protein
BTF_RS05840	COG3885	ferrous iron binding
BTF_RS05910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTF_RS05930	COG3872	metal-dependent enzyme
BTF_RS05935	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BTF_RS05935	COG0140	phosphoribosyl-ATP diphosphatase activity
BTF_RS05995	COG1522	sequence-specific DNA binding
BTF_RS06000	COG0436	Aminotransferase
BTF_RS06005	COG0180	Tryptophanyl-tRNA synthetase
BTF_RS06030	COG1595	DNA-templated transcription, initiation
BTF_RS06040	COG2197	response regulator
BTF_RS06045	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BTF_RS06050	COG1459	type II secretion system
BTF_RS06090	COG2165	general secretion pathway protein
BTF_RS06095	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BTF_RS06100	COG3769	mannosylglycerate metabolic process
BTF_RS06140	COG0167	dihydroorotate dehydrogenase activity
BTF_RS06155	COG0564	pseudouridine synthase activity
BTF_RS06180	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BTF_RS06180	COG2199	diguanylate cyclase activity
BTF_RS06190	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BTF_RS06195	COG1862	Preprotein translocase
BTF_RS06220	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BTF_RS06225	COG0671	phosphoesterase, PA-phosphatase related
BTF_RS06230	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTF_RS06230	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTF_RS06235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTF_RS06250	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BTF_RS06255	COG1160	GTP binding
BTF_RS06270	COG0484	heat shock protein binding
BTF_RS06310	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BTF_RS06315	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BTF_RS06325	COG0484	heat shock protein binding
BTF_RS06330	COG0789	Transcriptional regulator
BTF_RS06335	COG0542	response to heat
BTF_RS06345	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BTF_RS06350	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BTF_RS06375	COG2226	methyltransferase
BTF_RS06385	COG0406	alpha-ribazole phosphatase activity
BTF_RS06400	COG1253	flavin adenine dinucleotide binding
BTF_RS06410	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BTF_RS06420	COG0612	Peptidase, M16
BTF_RS06435	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BTF_RS06440	COG0298	carbon dioxide binding
BTF_RS06455	COG1309	transcriptional regulator
BTF_RS06500	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BTF_RS06515	COG2095	MarC family integral membrane protein
BTF_RS06555	COG1040	competence protein
BTF_RS06560	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BTF_RS06565	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BTF_RS06575	COG2003	Belongs to the UPF0758 family
BTF_RS06630	COG0512	Glutamine amidotransferase of anthranilate synthase
BTF_RS06635	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BTF_RS06645	COG0135	phosphoribosylanthranilate isomerase activity
BTF_RS06650	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BTF_RS06655	COG0133	tryptophan synthase activity
BTF_RS06660	COG0159	tryptophan synthase activity
BTF_RS06670	COG4608	Belongs to the ABC transporter superfamily
BTF_RS06680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTF_RS06685	COG0601	transmembrane transport
BTF_RS06690	COG0747	negative chemotaxis
BTF_RS06740	COG0735	belongs to the Fur family
BTF_RS06840	COG2205	protein histidine kinase activity
BTF_RS06920	COG2963	transposase activity
BTF_RS06925	COG2801	Transposase and inactivated derivatives
BTF_RS06955	COG0174	glutamine synthetase
BTF_RS06970	COG0745	RESPONSE REGULATOR receiver
BTF_RS06975	COG5002	protein histidine kinase activity
BTF_RS06985	COG2963	transposase activity
BTF_RS07010	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BTF_RS07045	COG4585	Histidine kinase
BTF_RS07050	COG2197	response regulator
BTF_RS07135	COG0745	RESPONSE REGULATOR receiver
BTF_RS07140	COG5002	protein histidine kinase activity
BTF_RS07140	COG0784	Response regulator, receiver
BTF_RS07140	COG2205	protein histidine kinase activity
BTF_RS07145	COG5002	protein histidine kinase activity
BTF_RS07210	COG1584	GPR1 FUN34 yaaH family protein
BTF_RS07215	COG4191	Histidine kinase
BTF_RS07235	COG1132	(ABC) transporter
BTF_RS07240	COG1032	radical SAM domain protein
BTF_RS07245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BTF_RS07250	COG1846	Transcriptional regulator
BTF_RS07275	COG0477	Major facilitator Superfamily
BTF_RS07280	COG1846	Transcriptional regulator
BTF_RS07295	COG1846	Transcriptional regulator
BTF_RS07310	COG2202	Pas domain
BTF_RS07310	COG2205	protein histidine kinase activity
BTF_RS07315	COG0745	RESPONSE REGULATOR receiver
BTF_RS07395	COG3260	NADH ubiquinone oxidoreductase 20
BTF_RS07400	COG3261	NADH dehydrogenase
BTF_RS07400	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
BTF_RS07405	COG0651	ATP synthesis coupled electron transport
BTF_RS07415	COG0650	Formate hydrogenlyase subunit 4
BTF_RS07420	COG0651	ATP synthesis coupled electron transport
BTF_RS07425	COG1803	Methylglyoxal synthase
BTF_RS07435	COG0668	transmembrane transport
BTF_RS07445	COG0702	epimerase
BTF_RS07450	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BTF_RS07455	COG0450	alkyl hydroperoxide reductase
BTF_RS07480	COG1704	LemA family
BTF_RS07485	COG0501	Belongs to the peptidase M48B family
BTF_RS07490	COG1045	serine acetyltransferase
BTF_RS07505	COG2226	methyltransferase
BTF_RS07515	COG1959	2 iron, 2 sulfur cluster binding
BTF_RS07535	COG0805	protein transport
BTF_RS07540	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BTF_RS07545	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BTF_RS07555	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BTF_RS07570	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BTF_RS07575	COG2137	regulation of response to DNA damage stimulus
BTF_RS07585	COG1692	metallophosphoesterase
BTF_RS07590	COG0613	PHP domain protein
BTF_RS07605	COG1720	tRNA m6t6A37 methyltransferase activity
BTF_RS07635	COG1131	(ABC) transporter
BTF_RS07640	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BTF_RS07675	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BTF_RS07675	COG4651	solute:proton antiporter activity
BTF_RS07680	COG1234	tRNA 3'-trailer cleavage
BTF_RS07690	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTF_RS07700	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BTF_RS07715	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
BTF_RS07725	COG3956	TIGRFAM MazG family protein
BTF_RS07730	COG2738	Putative neutral zinc metallopeptidase
BTF_RS07740	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BTF_RS07785	COG3728	DNA packaging
BTF_RS07785	COG5484	DNA packaging