locus-tag	class	description
ASJ33_RS00060	COG1584	GPR1 FUN34 yaaH family protein
ASJ33_RS00075	COG1132	(ABC) transporter
ASJ33_RS00080	COG1032	radical SAM domain protein
ASJ33_RS00085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASJ33_RS00090	COG1846	Transcriptional regulator
ASJ33_RS00115	COG0477	Major facilitator Superfamily
ASJ33_RS00135	COG1846	Transcriptional regulator
ASJ33_RS00150	COG2205	protein histidine kinase activity
ASJ33_RS00155	COG0745	RESPONSE REGULATOR receiver
ASJ33_RS00200	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ASJ33_RS00250	COG3260	NADH ubiquinone oxidoreductase 20
ASJ33_RS00255	COG3261	NADH dehydrogenase
ASJ33_RS00255	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ASJ33_RS00260	COG0651	ATP synthesis coupled electron transport
ASJ33_RS00270	COG0650	Formate hydrogenlyase subunit 4
ASJ33_RS00275	COG0651	ATP synthesis coupled electron transport
ASJ33_RS00280	COG1803	Methylglyoxal synthase
ASJ33_RS00290	COG0668	transmembrane transport
ASJ33_RS00300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASJ33_RS00305	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ASJ33_RS00310	COG0450	alkyl hydroperoxide reductase
ASJ33_RS00335	COG1704	LemA family
ASJ33_RS00340	COG0501	Belongs to the peptidase M48B family
ASJ33_RS00345	COG1045	serine acetyltransferase
ASJ33_RS00350	COG1324	tolerance protein
ASJ33_RS00355	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ASJ33_RS00360	COG2226	methyltransferase
ASJ33_RS00365	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ASJ33_RS00370	COG1959	2 iron, 2 sulfur cluster binding
ASJ33_RS00390	COG0805	protein transport
ASJ33_RS00395	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASJ33_RS00400	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASJ33_RS00410	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ASJ33_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ASJ33_RS00425	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ASJ33_RS00435	COG1418	mRNA catabolic process
ASJ33_RS00435	COG4372	Transposase
ASJ33_RS00440	COG1692	metallophosphoesterase
ASJ33_RS00445	COG0613	PHP domain protein
ASJ33_RS00450	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ASJ33_RS00460	COG1720	tRNA m6t6A37 methyltransferase activity
ASJ33_RS00480	COG0393	Putative heavy-metal-binding
ASJ33_RS00490	COG1131	(ABC) transporter
ASJ33_RS00495	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ASJ33_RS00525	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ASJ33_RS00530	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ASJ33_RS00530	COG4651	solute:proton antiporter activity
ASJ33_RS00535	COG1234	tRNA 3'-trailer cleavage
ASJ33_RS00545	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ASJ33_RS00555	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ASJ33_RS00570	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
ASJ33_RS00580	COG3956	TIGRFAM MazG family protein
ASJ33_RS00585	COG2738	Putative neutral zinc metallopeptidase
ASJ33_RS00590	COG0268	Binds directly to 16S ribosomal RNA
ASJ33_RS00595	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ASJ33_RS00605	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ASJ33_RS00610	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ASJ33_RS00615	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ASJ33_RS00620	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ASJ33_RS00625	COG0187	DNA topoisomerase II activity
ASJ33_RS00630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ASJ33_RS00635	COG0124	histidyl-tRNA synthetase
ASJ33_RS00645	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ASJ33_RS00650	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ASJ33_RS00660	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ASJ33_RS00670	COG0284	orotidine-5'-phosphate decarboxylase activity
ASJ33_RS00700	COG1490	D-aminoacyl-tRNA deacylase activity
ASJ33_RS00735	COG0569	domain protein
ASJ33_RS00745	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASJ33_RS00750	COG0569	domain protein
ASJ33_RS00755	COG1230	cation diffusion facilitator family transporter
ASJ33_RS00765	COG0306	phosphate transporter
ASJ33_RS00780	COG0543	2 iron, 2 sulfur cluster binding
ASJ33_RS00785	COG0493	'glutamate synthase
ASJ33_RS00800	COG2226	methyltransferase
ASJ33_RS00820	COG0012	GTP binding
ASJ33_RS00845	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ASJ33_RS00850	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ASJ33_RS00855	COG0343	queuine tRNA-ribosyltransferase activity
ASJ33_RS00860	COG1979	alcohol dehydrogenase
ASJ33_RS00875	COG0542	response to heat
ASJ33_RS00885	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ASJ33_RS00890	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ASJ33_RS00895	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ASJ33_RS00900	COG0215	cysteine-tRNA ligase activity
ASJ33_RS00910	COG4974	Belongs to the 'phage' integrase family
ASJ33_RS00990	COG0556	nucleotide-excision repair
ASJ33_RS01015	COG0746	molybdenum cofactor guanylyltransferase activity
ASJ33_RS01050	COG1307	EDD domain protein, DegV family
ASJ33_RS01055	COG1704	LemA family
ASJ33_RS01065	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ASJ33_RS01080	COG0437	4 iron, 4 sulfur cluster binding
ASJ33_RS01105	COG0693	protein deglycase activity
ASJ33_RS01110	COG0511	ligase activity, forming carbon-carbon bonds
ASJ33_RS01110	COG5016	pyruvate
ASJ33_RS01115	COG0439	Biotin carboxylase
ASJ33_RS01125	COG0493	'glutamate synthase
ASJ33_RS01130	COG1063	alcohol dehydrogenase
ASJ33_RS01135	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ASJ33_RS01150	COG0432	Pfam Uncharacterised protein family UPF0047
ASJ33_RS01155	COG0745	RESPONSE REGULATOR receiver
ASJ33_RS01180	COG4968	Prepilin-type N-terminal cleavage methylation domain
ASJ33_RS01185	COG0745	RESPONSE REGULATOR receiver
ASJ33_RS01190	COG5002	protein histidine kinase activity
ASJ33_RS01195	COG1803	Methylglyoxal synthase
ASJ33_RS01200	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ASJ33_RS01205	COG0573	inorganic phosphate transmembrane transporter activity
ASJ33_RS01210	COG0581	inorganic phosphate transmembrane transporter activity
ASJ33_RS01215	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ASJ33_RS01220	COG0704	Plays a role in the regulation of phosphate uptake
ASJ33_RS01255	COG2267	carboxylic ester hydrolase activity
ASJ33_RS01300	COG1396	sequence-specific DNA binding
ASJ33_RS01420	COG1404	Belongs to the peptidase S8 family
ASJ33_RS01445	COG4974	Belongs to the 'phage' integrase family
ASJ33_RS01595	COG0745	RESPONSE REGULATOR receiver
ASJ33_RS01620	COG0513	Belongs to the DEAD box helicase family
ASJ33_RS01635	COG5557	Pfam Polysulphide reductase, NrfD
ASJ33_RS01645	COG0742	ribosomal rna small subunit methyltransferase
ASJ33_RS01655	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ASJ33_RS01670	COG0495	leucyl-tRNA aminoacylation
ASJ33_RS01675	COG2081	HI0933 family
ASJ33_RS01680	COG0456	acetyltransferase
ASJ33_RS01680	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ASJ33_RS01695	COG1592	Rubrerythrin
ASJ33_RS01695	COG1773	rubredoxin
ASJ33_RS01710	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ASJ33_RS01715	COG0363	glucosamine-6-phosphate deaminase activity
ASJ33_RS01720	COG0667	Aldo Keto reductase
ASJ33_RS01750	COG0488	(ABC) transporter
ASJ33_RS01760	COG2081	HI0933 family
ASJ33_RS01810	COG0745	RESPONSE REGULATOR receiver
ASJ33_RS01815	COG2205	protein histidine kinase activity
ASJ33_RS01825	COG0745	RESPONSE REGULATOR receiver
ASJ33_RS01850	COG1752	Esterase of the alpha-beta hydrolase superfamily
ASJ33_RS01880	COG0123	including yeast histone deacetylase and acetoin utilization protein
ASJ33_RS01890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASJ33_RS01895	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASJ33_RS01900	COG0617	tRNA 3'-terminal CCA addition
ASJ33_RS01910	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ASJ33_RS01915	COG0335	large ribosomal subunit rRNA binding
ASJ33_RS01920	COG0336	Belongs to the RNA methyltransferase TrmD family
ASJ33_RS01925	COG2001	Belongs to the MraZ family
ASJ33_RS01930	COG0275	rRNA processing
ASJ33_RS01940	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ASJ33_RS01945	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ASJ33_RS01960	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASJ33_RS01965	COG1610	YqeY-like protein
ASJ33_RS02030	COG0793	Belongs to the peptidase S41A family
ASJ33_RS02030	COG3409	Peptidoglycan-binding domain 1 protein
ASJ33_RS02035	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ASJ33_RS02040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASJ33_RS02040	COG0072	phenylalanine-tRNA ligase activity
ASJ33_RS02045	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ASJ33_RS02050	COG0442	prolyl-tRNA aminoacylation
ASJ33_RS02065	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ASJ33_RS02070	COG4589	Belongs to the CDS family
ASJ33_RS02080	COG0233	cytoplasmic translational termination
ASJ33_RS02085	COG0528	UMP kinase activity
ASJ33_RS02090	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ASJ33_RS02095	COG0052	Belongs to the universal ribosomal protein uS2 family
ASJ33_RS02100	COG0047	phosphoribosylformylglycinamidine synthase activity
ASJ33_RS02105	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ASJ33_RS02130	COG0516	GMP reductase activity
ASJ33_RS02135	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ASJ33_RS02145	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASJ33_RS02150	COG0142	geranyltranstransferase activity
ASJ33_RS02155	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ASJ33_RS02165	COG0799	negative regulation of ribosome biogenesis
ASJ33_RS02170	COG0105	UTP biosynthetic process
ASJ33_RS02175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASJ33_RS02180	COG0802	atpase or kinase
ASJ33_RS02185	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ASJ33_RS02195	COG2226	methyltransferase
ASJ33_RS02200	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ASJ33_RS02220	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ASJ33_RS02225	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ASJ33_RS02240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASJ33_RS02245	COG3620	sequence-specific DNA binding
ASJ33_RS02245	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ASJ33_RS02245	COG0617	tRNA 3'-terminal CCA addition
ASJ33_RS02255	COG0842	Transport permease protein
ASJ33_RS02270	COG1597	lipid kinase activity
ASJ33_RS02285	COG1126	abc transporter atp-binding protein
ASJ33_RS02290	COG0765	amino acid transport
ASJ33_RS02310	COG0598	Magnesium transport protein CorA
ASJ33_RS02330	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ASJ33_RS02330	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ASJ33_RS02340	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ASJ33_RS02345	COG0525	valine-tRNA ligase activity
ASJ33_RS02365	COG0653	protein targeting
ASJ33_RS02370	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ASJ33_RS02380	COG1573	uracil-dna glycosylase
ASJ33_RS02385	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ASJ33_RS02390	COG1674	ftsk spoiiie
ASJ33_RS02395	COG0556	nucleotide-excision repair
ASJ33_RS02400	COG0632	four-way junction helicase activity
ASJ33_RS02405	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ASJ33_RS02410	COG0217	transcriptional regulatory protein
ASJ33_RS02415	COG0736	holo-[acyl-carrier-protein] synthase activity
ASJ33_RS02420	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ASJ33_RS02425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ASJ33_RS02435	COG0066	3-isopropylmalate dehydratase activity
ASJ33_RS02440	COG0538	isocitrate dehydrogenase activity
ASJ33_RS02445	COG0039	L-malate dehydrogenase activity
ASJ33_RS02455	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ASJ33_RS02465	COG0537	adenosine 5'-monophosphoramidase activity
ASJ33_RS02475	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ASJ33_RS02480	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ASJ33_RS02490	COG1605	Chorismate mutase
ASJ33_RS02490	COG0287	Prephenate dehydrogenase
ASJ33_RS02495	COG1605	Chorismate mutase
ASJ33_RS02495	COG0077	Prephenate dehydratase
ASJ33_RS02500	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ASJ33_RS02510	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ASJ33_RS02520	COG0710	3-dehydroquinate dehydratase activity
ASJ33_RS02525	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ASJ33_RS02530	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ASJ33_RS02535	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ASJ33_RS02545	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ASJ33_RS02550	COG0051	transcription antitermination factor activity, RNA binding
ASJ33_RS02555	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ASJ33_RS02580	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ASJ33_RS02585	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ASJ33_RS02605	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ASJ33_RS02615	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ASJ33_RS02630	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ASJ33_RS02640	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ASJ33_RS02650	COG0200	Binds to the 23S rRNA
ASJ33_RS02665	COG0024	Methionine aminopeptidase
ASJ33_RS02685	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ASJ33_RS02695	COG0202	RNA polymerase activity
ASJ33_RS02700	COG0203	ribosomal protein L17
ASJ33_RS02710	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ASJ33_RS02730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASJ33_RS02740	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ASJ33_RS02745	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ASJ33_RS02765	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ASJ33_RS02770	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ASJ33_RS02780	COG1131	(ABC) transporter
ASJ33_RS02785	COG2030	dehydratase
ASJ33_RS02810	COG0312	modulator of DNA gyrase
ASJ33_RS02815	COG0312	modulator of DNA gyrase
ASJ33_RS02820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASJ33_RS02830	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ASJ33_RS02835	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ASJ33_RS02840	COG1881	PFAM PEBP family protein
ASJ33_RS02845	COG1011	Hydrolase
ASJ33_RS02850	COG0019	diaminopimelate decarboxylase activity
ASJ33_RS02855	COG0470	DNA polymerase III
ASJ33_RS02860	COG1774	PSP1 C-terminal conserved region
ASJ33_RS02880	COG0305	Participates in initiation and elongation during chromosome replication
ASJ33_RS02885	COG0359	binds to the 23S rRNA
ASJ33_RS02890	COG0492	ferredoxin-NADP+ reductase activity
ASJ33_RS02895	COG0416	fatty acid biosynthetic process
ASJ33_RS02900	COG1924	4 iron, 4 sulfur cluster binding
ASJ33_RS02905	COG1473	amidohydrolase
ASJ33_RS02925	COG0419	ATPase involved in DNA repair
ASJ33_RS02930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASJ33_RS02935	COG0358	DNA primase activity
ASJ33_RS02940	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ASJ33_RS02945	COG0574	Belongs to the PEP-utilizing enzyme family
ASJ33_RS02945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ASJ33_RS02960	COG0356	it plays a direct role in the translocation of protons across the membrane
ASJ33_RS02970	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ASJ33_RS02975	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ASJ33_RS02980	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ASJ33_RS02985	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ASJ33_RS02990	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ASJ33_RS02995	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ASJ33_RS03000	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ASJ33_RS03010	COG0228	four-way junction DNA binding
ASJ33_RS03020	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ASJ33_RS03030	COG2003	Belongs to the UPF0758 family
ASJ33_RS03035	COG0747	negative chemotaxis
ASJ33_RS03065	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ASJ33_RS03085	COG0598	Magnesium transport protein CorA
ASJ33_RS03090	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ASJ33_RS03095	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ASJ33_RS03100	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ASJ33_RS03130	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ASJ33_RS03140	COG0148	phosphopyruvate hydratase activity
ASJ33_RS03150	COG0193	aminoacyl-tRNA hydrolase activity
ASJ33_RS03155	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ASJ33_RS03165	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ASJ33_RS03170	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASJ33_RS03180	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ASJ33_RS03195	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ASJ33_RS03200	COG2255	four-way junction helicase activity
ASJ33_RS03205	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ASJ33_RS03210	COG0456	acetyltransferase
ASJ33_RS03225	COG2226	methyltransferase
ASJ33_RS03235	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
ASJ33_RS03240	COG3259	Nickel-dependent hydrogenase
ASJ33_RS03260	COG0785	Cytochrome C biogenesis protein
ASJ33_RS03290	COG5002	protein histidine kinase activity
ASJ33_RS03310	COG1181	Belongs to the D-alanine--D-alanine ligase family
ASJ33_RS03315	COG0735	belongs to the Fur family
ASJ33_RS03320	COG3443	Belongs to the bacterial solute-binding protein 9 family
ASJ33_RS03320	COG0803	Belongs to the bacterial solute-binding protein 9 family
ASJ33_RS03325	COG1121	(ABC) transporter
ASJ33_RS03330	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ASJ33_RS03340	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ASJ33_RS03360	COG0589	response to stress
ASJ33_RS03365	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ASJ33_RS03370	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ASJ33_RS03375	COG0698	ribose 5-phosphate isomerase
ASJ33_RS03380	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ASJ33_RS03390	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ASJ33_RS03400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ASJ33_RS03405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASJ33_RS03410	COG1120	ATPase activity
ASJ33_RS03425	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ASJ33_RS03435	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ASJ33_RS03440	COG0406	alpha-ribazole phosphatase activity
ASJ33_RS03445	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
ASJ33_RS03450	COG3118	belongs to the thioredoxin family
ASJ33_RS03460	COG2197	response regulator
ASJ33_RS03485	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ASJ33_RS03500	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ASJ33_RS03515	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ASJ33_RS03520	COG0544	peptidyl-prolyl cis-trans isomerase activity
ASJ33_RS03525	COG0740	serine-type endopeptidase activity
ASJ33_RS03545	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ASJ33_RS03550	COG0006	proline dipeptidase activity
ASJ33_RS03555	COG4974	Belongs to the 'phage' integrase family
ASJ33_RS03560	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ASJ33_RS03565	COG0758	DNA mediated transformation
ASJ33_RS03565	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ASJ33_RS03580	COG0475	glutathione-regulated potassium exporter activity
ASJ33_RS03600	COG0674	pyruvate-flavodoxin oxidoreductase activity
ASJ33_RS03605	COG1013	pyruvate-flavodoxin oxidoreductase activity
ASJ33_RS03620	COG1034	ATP synthesis coupled electron transport
ASJ33_RS03650	COG1028	Short-chain dehydrogenase reductase Sdr
ASJ33_RS03655	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ASJ33_RS03665	COG0436	Aminotransferase
ASJ33_RS03670	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ASJ33_RS03675	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ASJ33_RS03685	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
ASJ33_RS03690	COG0126	phosphoglycerate kinase activity
ASJ33_RS03695	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ASJ33_RS03715	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ASJ33_RS03725	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ASJ33_RS03730	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ASJ33_RS03735	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ASJ33_RS03760	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ASJ33_RS03795	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ASJ33_RS03810	COG0517	IMP dehydrogenase activity
ASJ33_RS03810	COG1994	Peptidase M50
ASJ33_RS03815	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASJ33_RS03835	COG0517	IMP dehydrogenase activity
ASJ33_RS03835	COG1994	Peptidase M50
ASJ33_RS03840	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ASJ33_RS03850	COG3854	ATPases associated with a variety of cellular activities
ASJ33_RS03855	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ASJ33_RS03860	COG0482	sulfurtransferase activity
ASJ33_RS03865	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ASJ33_RS03870	COG0792	nuclease activity
ASJ33_RS03875	COG0352	thiamine-phosphate diphosphorylase activity
ASJ33_RS03885	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ASJ33_RS03890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASJ33_RS03900	COG0423	glycine-tRNA ligase activity
ASJ33_RS03905	COG0420	3'-5' exonuclease activity
ASJ33_RS03910	COG1187	pseudouridine synthase activity
ASJ33_RS03920	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ASJ33_RS03925	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ASJ33_RS03965	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ASJ33_RS03970	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ASJ33_RS03985	COG1695	Transcriptional regulator
ASJ33_RS04010	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASJ33_RS04020	COG1396	sequence-specific DNA binding
ASJ33_RS04050	COG0484	heat shock protein binding
ASJ33_RS04130	COG1404	Belongs to the peptidase S8 family
ASJ33_RS04170	COG4974	Belongs to the 'phage' integrase family
ASJ33_RS04190	COG2217	Heavy metal translocating P-type atpase
ASJ33_RS04205	COG1937	Protein conserved in bacteria
ASJ33_RS04255	COG0210	DNA helicase
ASJ33_RS04280	COG1121	(ABC) transporter
ASJ33_RS04290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASJ33_RS04290	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ASJ33_RS04300	COG1131	(ABC) transporter
ASJ33_RS04305	COG0842	Transport permease protein
ASJ33_RS04310	COG0396	ATPase activity
ASJ33_RS04315	COG0719	Fe-S assembly protein
ASJ33_RS04320	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ASJ33_RS04360	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ASJ33_RS04365	COG0473	3-isopropylmalate dehydrogenase activity
ASJ33_RS04370	COG0066	3-isopropylmalate dehydratase activity
ASJ33_RS04375	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ASJ33_RS04380	COG1285	pathogenesis
ASJ33_RS04385	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ASJ33_RS04410	COG0009	L-threonylcarbamoyladenylate synthase
ASJ33_RS04425	COG0151	Belongs to the GarS family
ASJ33_RS04430	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ASJ33_RS04435	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ASJ33_RS04440	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ASJ33_RS04445	COG0131	Imidazoleglycerol-phosphate dehydratase
ASJ33_RS04450	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ASJ33_RS04455	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ASJ33_RS04460	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ASJ33_RS04465	COG0124	histidyl-tRNA synthetase
ASJ33_RS04490	COG4152	abc transporter atp-binding protein
ASJ33_RS04520	COG0577	efflux transmembrane transporter activity
ASJ33_RS04520	COG1136	(ABC) transporter
ASJ33_RS04525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ASJ33_RS04535	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ASJ33_RS04535	COG2111	Na H antiporter
ASJ33_RS04540	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ASJ33_RS04545	COG3260	NADH ubiquinone oxidoreductase 20
ASJ33_RS04565	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ASJ33_RS04565	COG0493	'glutamate synthase
ASJ33_RS04580	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ASJ33_RS04585	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ASJ33_RS04590	COG1846	Transcriptional regulator
ASJ33_RS04595	COG2409	Drug exporters of the RND superfamily
ASJ33_RS04595	COG1033	growth of symbiont in host cell
ASJ33_RS04685	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASJ33_RS04695	COG0649	NAD binding
ASJ33_RS04700	COG0649	NAD binding
ASJ33_RS04705	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ASJ33_RS04710	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASJ33_RS04720	COG0713	ATP synthesis coupled electron transport
ASJ33_RS04725	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ASJ33_RS04730	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASJ33_RS04740	COG0084	hydrolase, TatD family'
ASJ33_RS04745	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ASJ33_RS04760	COG0411	ABC transporter
ASJ33_RS04770	COG0318	PFAM AMP-dependent synthetase and ligase
ASJ33_RS04800	COG0318	PFAM AMP-dependent synthetase and ligase
ASJ33_RS04825	COG0822	iron-sulfur transferase activity
ASJ33_RS04835	COG2217	Heavy metal translocating P-type atpase
ASJ33_RS04875	COG0107	imidazoleglycerol-phosphate synthase activity
ASJ33_RS04885	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASJ33_RS04890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ASJ33_RS04895	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ASJ33_RS04895	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ASJ33_RS04900	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ASJ33_RS04905	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ASJ33_RS04910	COG1111	helicase
ASJ33_RS04910	COG1205	dead DEAH box helicase
ASJ33_RS04920	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ASJ33_RS04925	COG1185	polyribonucleotide nucleotidyltransferase activity
ASJ33_RS04935	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ASJ33_RS04940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASJ33_RS04960	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ASJ33_RS04965	COG0438	transferase activity, transferring glycosyl groups
ASJ33_RS04970	COG1260	myo-inositol-1-phosphate synthase
ASJ33_RS04980	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ASJ33_RS04985	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ASJ33_RS04995	COG0195	Participates in both transcription termination and antitermination
ASJ33_RS05000	COG0606	chelatase, subunit chli
ASJ33_RS05020	COG0222	ribosome binding
ASJ33_RS05025	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ASJ33_RS05030	COG0081	regulation of translation
ASJ33_RS05040	COG0250	Participates in transcription elongation, termination and antitermination
ASJ33_RS05045	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ASJ33_RS05090	COG0640	Transcriptional regulator
ASJ33_RS05095	COG0701	Predicted permease
ASJ33_RS05110	COG2211	Major facilitator Superfamily
ASJ33_RS05115	COG0348	domain, Protein
ASJ33_RS05115	COG3901	Regulator of nitric oxide reductase transcription
ASJ33_RS05140	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ASJ33_RS05180	COG1395	domain, Protein
ASJ33_RS05335	COG1476	TRANSCRIPTIONal
ASJ33_RS05350	COG4974	Belongs to the 'phage' integrase family
ASJ33_RS05380	COG1254	Belongs to the acylphosphatase family
ASJ33_RS05395	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ASJ33_RS05405	COG1307	EDD domain protein, DegV family
ASJ33_RS05410	COG0318	PFAM AMP-dependent synthetase and ligase
ASJ33_RS05415	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
ASJ33_RS05420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASJ33_RS05425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASJ33_RS05430	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ASJ33_RS05435	COG1847	R3H domain protein
ASJ33_RS05440	COG0706	membrane insertase activity
ASJ33_RS05450	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ASJ33_RS05460	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ASJ33_RS05465	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ASJ33_RS05470	COG0629	single-stranded DNA binding
ASJ33_RS05475	COG0360	Binds together with S18 to 16S ribosomal RNA
ASJ33_RS05675	COG4695	Portal protein
ASJ33_RS05795	COG0251	oxidation-reduction process
ASJ33_RS05810	COG0497	DNA recombination
ASJ33_RS05815	COG0697	spore germination
ASJ33_RS05825	COG0745	RESPONSE REGULATOR receiver
ASJ33_RS05830	COG2205	protein histidine kinase activity
ASJ33_RS05835	COG4608	Belongs to the ABC transporter superfamily
ASJ33_RS05840	COG0444	Belongs to the ABC transporter superfamily
ASJ33_RS05845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASJ33_RS05850	COG0601	transmembrane transport
ASJ33_RS05855	COG4166	transmembrane transport
ASJ33_RS05860	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ASJ33_RS05865	COG2197	response regulator
ASJ33_RS05875	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ASJ33_RS05895	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ASJ33_RS05895	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASJ33_RS05900	COG0174	glutamine synthetase
ASJ33_RS05910	COG0004	ammonium transporteR
ASJ33_RS05915	COG0745	RESPONSE REGULATOR receiver
ASJ33_RS05925	COG0069	glutamate synthase activity
ASJ33_RS05930	COG0107	imidazoleglycerol-phosphate synthase activity
ASJ33_RS05935	COG0067	glutamate synthase
ASJ33_RS05940	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ASJ33_RS05950	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ASJ33_RS05950	COG0493	'glutamate synthase
ASJ33_RS05960	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ASJ33_RS05980	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
ASJ33_RS05985	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASJ33_RS05990	COG0726	polysaccharide deacetylase
ASJ33_RS06010	COG2197	response regulator
ASJ33_RS06015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASJ33_RS06015	COG1042	CoA-binding domain protein
ASJ33_RS06015	COG0045	succinate-CoA ligase (ADP-forming) activity
ASJ33_RS06040	COG0735	belongs to the Fur family
ASJ33_RS06060	COG1132	(ABC) transporter
ASJ33_RS06090	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ASJ33_RS06095	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ASJ33_RS06095	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ASJ33_RS06105	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASJ33_RS06105	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASJ33_RS06120	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ASJ33_RS06130	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ASJ33_RS06135	COG0210	DNA helicase
ASJ33_RS06145	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ASJ33_RS06150	COG0540	Belongs to the ATCase OTCase family
ASJ33_RS06155	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ASJ33_RS06160	COG0505	Belongs to the CarA family
ASJ33_RS06165	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ASJ33_RS06170	COG0543	2 iron, 2 sulfur cluster binding
ASJ33_RS06175	COG0302	gtp cyclohydrolase
ASJ33_RS06180	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ASJ33_RS06185	COG0460	homoserine dehydrogenase
ASJ33_RS06190	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASJ33_RS06195	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ASJ33_RS06200	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASJ33_RS06205	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ASJ33_RS06210	COG2890	protein-(glutamine-N5) methyltransferase activity
ASJ33_RS06215	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ASJ33_RS06230	COG4974	Belongs to the 'phage' integrase family
ASJ33_RS06235	COG0322	excinuclease ABC activity
ASJ33_RS06245	COG0561	phosphatase activity
ASJ33_RS06250	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ASJ33_RS06270	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
ASJ33_RS06275	COG1980	fructose-bisphosphate aldolase activity
ASJ33_RS06280	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ASJ33_RS06285	COG0592	DNA-directed DNA polymerase activity
ASJ33_RS06305	COG5002	protein histidine kinase activity
ASJ33_RS06355	COG0788	formyltetrahydrofolate deformylase activity
ASJ33_RS06370	COG0798	PFAM Bile acid sodium symporter
ASJ33_RS06375	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASJ33_RS06380	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASJ33_RS06400	COG0640	Transcriptional regulator
ASJ33_RS06415	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ASJ33_RS06435	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ASJ33_RS06445	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ASJ33_RS06455	COG0137	argininosuccinate synthase activity
ASJ33_RS06460	COG0165	Argininosuccinate lyase
ASJ33_RS06465	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ASJ33_RS06475	COG1307	EDD domain protein, DegV family
ASJ33_RS06485	COG1307	EDD domain protein, DegV family
ASJ33_RS06490	COG1307	EDD domain protein, DegV family
ASJ33_RS06495	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ASJ33_RS06505	COG0018	arginyl-trna synthetase
ASJ33_RS06515	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ASJ33_RS06535	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ASJ33_RS06540	COG1028	Short-chain dehydrogenase reductase Sdr
ASJ33_RS06545	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ASJ33_RS06555	COG1032	radical SAM domain protein
ASJ33_RS06560	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ASJ33_RS06565	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ASJ33_RS06580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASJ33_RS06590	COG0789	Transcriptional regulator
ASJ33_RS06600	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ASJ33_RS06610	COG1058	Belongs to the CinA family
ASJ33_RS06610	COG1546	Belongs to the CinA family
ASJ33_RS06645	COG1217	gtp-binding protein TYPA
ASJ33_RS06665	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ASJ33_RS06685	COG3422	double-strand break repair
ASJ33_RS06695	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ASJ33_RS06710	COG2078	PFAM AMMECR1 domain protein
ASJ33_RS06710	COG3885	ferrous iron binding
ASJ33_RS06750	COG0655	NAD(P)H dehydrogenase (quinone) activity
ASJ33_RS06770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASJ33_RS06775	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ASJ33_RS06785	COG0254	rRNA binding
ASJ33_RS06790	COG3872	metal-dependent enzyme
ASJ33_RS06795	COG0140	phosphoribosyl-ATP diphosphatase activity
ASJ33_RS06795	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ASJ33_RS06805	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ASJ33_RS06820	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ASJ33_RS06825	COG0154	amidase activity
ASJ33_RS06855	COG1522	sequence-specific DNA binding
ASJ33_RS06860	COG0436	Aminotransferase
ASJ33_RS06865	COG0180	Tryptophanyl-tRNA synthetase
ASJ33_RS06870	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ASJ33_RS06880	COG1105	Belongs to the carbohydrate kinase PfkB family
ASJ33_RS06890	COG1595	DNA-templated transcription, initiation
ASJ33_RS06900	COG2197	response regulator
ASJ33_RS06905	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ASJ33_RS06910	COG1459	type II secretion system
ASJ33_RS06960	COG3769	mannosylglycerate metabolic process
ASJ33_RS06995	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ASJ33_RS07005	COG0167	dihydroorotate dehydrogenase activity
ASJ33_RS07010	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ASJ33_RS07015	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ASJ33_RS07020	COG0564	pseudouridine synthase activity
ASJ33_RS07045	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ASJ33_RS07045	COG2199	diguanylate cyclase activity
ASJ33_RS07055	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ASJ33_RS07060	COG1862	Preprotein translocase
ASJ33_RS07065	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASJ33_RS07085	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ASJ33_RS07090	COG0671	phosphoesterase, PA-phosphatase related
ASJ33_RS07095	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASJ33_RS07095	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASJ33_RS07100	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASJ33_RS07115	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ASJ33_RS07120	COG1160	GTP binding
ASJ33_RS07130	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ASJ33_RS07135	COG0484	heat shock protein binding
ASJ33_RS07145	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ASJ33_RS07150	COG1420	regulation of RNA biosynthetic process
ASJ33_RS07175	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ASJ33_RS07180	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ASJ33_RS07185	COG0504	CTP synthase activity
ASJ33_RS07190	COG0484	heat shock protein binding
ASJ33_RS07195	COG0789	Transcriptional regulator
ASJ33_RS07200	COG0542	response to heat
ASJ33_RS07210	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ASJ33_RS07220	COG2226	methyltransferase
ASJ33_RS07240	COG2226	methyltransferase
ASJ33_RS07250	COG0406	alpha-ribazole phosphatase activity
ASJ33_RS07265	COG1253	flavin adenine dinucleotide binding
ASJ33_RS07275	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ASJ33_RS07280	COG0459	protein refolding
ASJ33_RS07285	COG0612	Peptidase, M16
ASJ33_RS07290	COG0375	protein maturation
ASJ33_RS07300	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ASJ33_RS07305	COG0298	carbon dioxide binding
ASJ33_RS07315	COG0309	Hydrogenase expression formation protein (HypE)
ASJ33_RS07320	COG1309	transcriptional regulator
ASJ33_RS07360	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ASJ33_RS07370	COG2095	MarC family integral membrane protein
ASJ33_RS07390	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ASJ33_RS07410	COG1040	competence protein
ASJ33_RS07415	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ASJ33_RS07420	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ASJ33_RS07430	COG2003	Belongs to the UPF0758 family
ASJ33_RS07475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASJ33_RS07485	COG0512	Glutamine amidotransferase of anthranilate synthase
ASJ33_RS07490	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ASJ33_RS07500	COG0135	phosphoribosylanthranilate isomerase activity
ASJ33_RS07505	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ASJ33_RS07510	COG0133	tryptophan synthase activity
ASJ33_RS07535	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ASJ33_RS07550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASJ33_RS07555	COG0601	transmembrane transport
ASJ33_RS07560	COG0747	negative chemotaxis
ASJ33_RS07590	COG2814	Major facilitator Superfamily
ASJ33_RS07595	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ASJ33_RS07605	COG0735	belongs to the Fur family
ASJ33_RS07610	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ASJ33_RS07645	COG1475	DNA binding
ASJ33_RS07775	COG0174	glutamine synthetase
ASJ33_RS07795	COG1475	DNA binding
ASJ33_RS07825	COG0587	DNA-directed DNA polymerase activity
ASJ33_RS07865	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ASJ33_RS07875	COG0556	nucleotide-excision repair
ASJ33_RS07890	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ASJ33_RS07930	COG1857	crispr-associated protein
ASJ33_RS07970	COG2894	cell division
ASJ33_RS07980	COG2205	protein histidine kinase activity
ASJ33_RS08065	COG1475	DNA binding
ASJ33_RS08185	COG0174	glutamine synthetase
ASJ33_RS08205	COG2205	protein histidine kinase activity
ASJ33_RS08240	COG0745	RESPONSE REGULATOR receiver
ASJ33_RS08245	COG0745	RESPONSE REGULATOR receiver
ASJ33_RS08310	COG0745	RESPONSE REGULATOR receiver