locus-tag	class	description
HAV23_RS00010	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HAV23_RS00015	ENOG4108VX5	3-methyladenine DNA glycosylase
HAV23_RS00020	ENOG4108ZIT	Ferredoxin, 2FE-2S
HAV23_RS00025	ENOG41069FQ	Metallo-beta-lactamase superfamily
HAV23_RS00050	ENOG4105C22	threonyL-tRNA synthetase
HAV23_RS00060	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
HAV23_RS00075	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HAV23_RS00080	ENOG4108M3P	Membrane
HAV23_RS00085	ENOG4108Z0R	Transferase
HAV23_RS00095	ENOG41065KQ	synthase
HAV23_RS00100	ENOG41080V7	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HAV23_RS00110	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HAV23_RS00130	ENOG41083G8	Multidrug resistance protein MdtM
HAV23_RS00145	ENOG4105JRK	feS assembly protein SufD
HAV23_RS00170	ENOG4105DIW	FeS assembly protein SUFB
HAV23_RS00175	ENOG4105C3K	feS assembly ATPase SufC
HAV23_RS00190	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HAV23_RS00195	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HAV23_RS00200	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HAV23_RS00205	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HAV23_RS00210	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HAV23_RS00215	ENOG410856V	50S ribosomal protein L30
HAV23_RS00220	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HAV23_RS00225	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HAV23_RS00230	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HAV23_RS00235	ENOG4108IV0	ABC, transporter
HAV23_RS00240	ENOG4105C0Z	ABC transporter
HAV23_RS00245	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HAV23_RS00250	ENOG4105C32	Amino acid ABC transporter (Permease)
HAV23_RS00255	ENOG4105CP9	extracellular ligand-binding receptor
HAV23_RS00260	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HAV23_RS00265	ENOG41067V7	50S ribosomal protein L36
HAV23_RS00270	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HAV23_RS00275	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HAV23_RS00280	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HAV23_RS00285	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HAV23_RS00290	ENOG4108ZT0	50S ribosomal protein l17
HAV23_RS00295	ENOG4105CFP	Peptidase U32
HAV23_RS00310	ENOG4108IUZ	ABC transporter
HAV23_RS00315	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
HAV23_RS00340	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HAV23_RS00355	ENOG4107QX8	SPFH domain, Band 7 family protein
HAV23_RS00365	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HAV23_RS00380	ENOG4108Q5F	Tetr family transcriptional regulator
HAV23_RS00385	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HAV23_RS00390	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HAV23_RS00400	ENOG4105VG0	50S ribosomal protein l34
HAV23_RS00410	ENOG4106PMH	Extracellular solute-binding protein family 3
HAV23_RS00415	ENOG4105E5Q	amino acid AbC transporter
HAV23_RS00440	ENOG4105D52	delta-aminolevulinic acid dehydratase
HAV23_RS00460	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HAV23_RS00465	ENOG4105VG1	fes assembly suf system protein
HAV23_RS00470	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
HAV23_RS00485	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HAV23_RS00505	ENOG4108XI2	Domain of unknown function (DUF1963)
HAV23_RS00510	ENOG4105C8T	Leucyl-tRNA synthetase
HAV23_RS00535	ENOG4105C83	adenylosuccinate lyase
HAV23_RS00590	ENOG4108FXY	Cys/Met metabolism PLP-dependent enzyme
HAV23_RS00595	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HAV23_RS00615	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HAV23_RS00620	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HAV23_RS00635	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HAV23_RS00650	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HAV23_RS00655	ENOG4105D7T	ABC transporter
HAV23_RS00665	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
HAV23_RS00675	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
HAV23_RS00680	ENOG4105CMR	udp-glucose 4-epimerase
HAV23_RS00730	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
HAV23_RS00760	ENOG4106FN3	tellurium resistance protein
HAV23_RS00810	ENOG4105E3H	phosphoglycerate mutase
HAV23_RS00840	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HAV23_RS00890	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HAV23_RS00895	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HAV23_RS00900	ENOG4105BZU	Histidine kinase
HAV23_RS00925	ENOG4107S1Q	Phosphatase
HAV23_RS00955	ENOG4105DHF	Membrane
HAV23_RS00985	ENOG4105VZ8	Transcriptional regulator
HAV23_RS00990	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HAV23_RS00995	ENOG4105CPC	Aldo Keto reductase
HAV23_RS01005	ENOG4105IJD	ferritin dps family protein
HAV23_RS01010	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HAV23_RS01025	ENOG4105CHM	Aminotransferase
HAV23_RS01035	ENOG41071YG	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HAV23_RS01050	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HAV23_RS01060	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HAV23_RS01065	ENOG4105EAD	ABC transporter
HAV23_RS01070	ENOG4107R0W	ABC transporter
HAV23_RS01085	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HAV23_RS01090	ENOG410850P	UPF0102 protein
HAV23_RS01095	ENOG4105CC5	ABC transporter
HAV23_RS01125	ENOG4108UVJ	appr-1-p processing domain protein
HAV23_RS01130	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HAV23_RS01135	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HAV23_RS01155	ENOG4105VF7	tolerance protein
HAV23_RS01180	ENOG4105BZU	Histidine kinase
HAV23_RS01185	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HAV23_RS01215	ENOG4107SWG	transcriptional regulator MERR family
HAV23_RS01220	ENOG4105DXB	Major Facilitator superfamily
HAV23_RS01225	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HAV23_RS01240	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
HAV23_RS01245	ENOG4105DD7	kinase (PfkB family
HAV23_RS01270	ENOG4105CPC	Aldo Keto reductase
HAV23_RS01290	ENOG4107YAU	phenylacetic acid degradation protein
HAV23_RS01295	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HAV23_RS01300	ENOG4105YB8	TM2 domain containing protein
HAV23_RS01310	ENOG4105DHQ	Histidine kinase
HAV23_RS01320	ENOG4108Z4U	Ferredoxin
HAV23_RS01330	ENOG4107QRG	dna polymerase iii
HAV23_RS01335	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HAV23_RS01350	ENOG4107SVH	Potassium channel protein
HAV23_RS01360	ENOG4105CEV	competence damage-inducible protein
HAV23_RS01365	ENOG4108784	2'-5' rna ligase
HAV23_RS01370	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HAV23_RS01390	ENOG41081FY	multiple antibiotic resistance (MarC)-related
HAV23_RS01400	ENOG4105DIN	metallophosphoesterase
HAV23_RS01405	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HAV23_RS01425	ENOG4105K8N	protein family UPF0079, ATPase
HAV23_RS01430	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HAV23_RS01440	ENOG4107RB3	L-asparaginase
HAV23_RS01445	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HAV23_RS01455	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HAV23_RS01460	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HAV23_RS01470	ENOG4105DWY	Agmatine deiminase
HAV23_RS01480	ENOG4105CSU	acyl-Coa dehydrogenase
HAV23_RS01495	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HAV23_RS01505	ENOG41067VY	50S ribosomal protein L32
HAV23_RS01515	ENOG4107ZT3	family UPF0126
HAV23_RS01525	ENOG4107QN2	dihydrolipoyl dehydrogenase
HAV23_RS01535	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HAV23_RS01550	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HAV23_RS01555	ENOG4108RZE	Tetr family transcriptional regulator
HAV23_RS01570	ENOG4105BZ1	(ABC) transporter
HAV23_RS01580	ENOG4105DXM	phenylacetic acid degradation protein
HAV23_RS01590	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
HAV23_RS01595	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
HAV23_RS01605	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
HAV23_RS01610	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
HAV23_RS01615	ENOG41082JC	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HAV23_RS01625	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
HAV23_RS01655	ENOG410630P	Transcriptional regulator
HAV23_RS01660	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HAV23_RS01670	ENOG4105D7N	magnesium and cobalt transport protein CorA
HAV23_RS01680	ENOG4105MSB	protein, conserved in bacteria
HAV23_RS01710	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HAV23_RS01715	ENOG4105KA0	thioesterase Superfamily protein
HAV23_RS01725	ENOG4105CKI	cobalamin synthesis protein
HAV23_RS01735	ENOG4105C6E	dna polymerase iii
HAV23_RS01755	ENOG4105ETX	regulatoR
HAV23_RS01760	ENOG4105DHQ	Histidine kinase
HAV23_RS01765	ENOG4105CN5	Metallo-Beta-Lactamase
HAV23_RS01775	ENOG4105BZU	Histidine kinase
HAV23_RS01790	ENOG41080FJ	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HAV23_RS01795	ENOG4105CTD	carboxy-peptidase
HAV23_RS01840	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
HAV23_RS01845	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HAV23_RS01850	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HAV23_RS01865	ENOG4105CSM	endonuclease III
HAV23_RS01890	ENOG4107RRU	Involved in both the arginine and lysine biosynthetic pathways (By similarity)
HAV23_RS01910	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HAV23_RS01935	ENOG4105C59	p-type ATPase
HAV23_RS01980	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HAV23_RS01985	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
HAV23_RS01995	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HAV23_RS02015	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
HAV23_RS02020	ENOG4108JJB	ABC transporter
HAV23_RS02025	ENOG4107ZYJ	bioY protein
HAV23_RS02030	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HAV23_RS02075	ENOG4105CHU	acetyl-coa acetyltransferase
HAV23_RS02110	ENOG4106RE7	Cytochrome
HAV23_RS02115	ENOG4105F38	ABC transporter, permease
HAV23_RS02135	ENOG4105BZU	Histidine kinase
HAV23_RS02140	ENOG4105BZU	Histidine kinase
HAV23_RS02150	ENOG41079SJ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HAV23_RS02155	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HAV23_RS02160	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HAV23_RS02165	ENOG4105CNI	cell division protein FtsW
HAV23_RS02175	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HAV23_RS02190	ENOG4106UW1	Major Facilitator superfamily
HAV23_RS02210	ENOG4108SA1	esterase
HAV23_RS02225	ENOG4106B0N	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HAV23_RS02230	ENOG4108UKI	Enoyl-CoA hydratase
HAV23_RS02235	ENOG4105MA4	psp1 domain protein
HAV23_RS02240	ENOG4105KME	endoribonuclease L-psp
HAV23_RS02245	ENOG4108ZF3	Phosphatase
HAV23_RS02255	ENOG4105C1V	Peptidase, M16
HAV23_RS02295	ENOG4105DSE	periplasmic solute binding protein
HAV23_RS02300	ENOG4106633	50S ribosomal protein l28
HAV23_RS02305	ENOG4107QJT	sodium dicarboxylate symporter
HAV23_RS02310	ENOG4107QN2	dihydrolipoyl dehydrogenase
HAV23_RS02335	ENOG4105KHC	sulfurtransferase
HAV23_RS02350	ENOG4108VW6	Pfam:UPF0157
HAV23_RS02360	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HAV23_RS02365	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
HAV23_RS02390	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
HAV23_RS02395	ENOG4105CAT	Cytidine monophosphate kinase
HAV23_RS02415	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HAV23_RS02420	ENOG4105CDY	transcriptional regulatory protein
HAV23_RS02425	ENOG4105D74	hydrolase
HAV23_RS02435	ENOG4105F6J	Alpha beta hydrolase fold
HAV23_RS02440	ENOG4105HHA	aminodeoxychorismate lyase
HAV23_RS02455	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HAV23_RS02460	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HAV23_RS02465	ENOG4105C5X	domain protein
HAV23_RS02505	ENOG4105DF6	Fe-S oxidoreductase
HAV23_RS02515	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HAV23_RS02520	ENOG4105C75	arginyL-tRNA synthetase
HAV23_RS02535	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HAV23_RS02545	ENOG4108IMY	Transcriptional regulator
HAV23_RS02550	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HAV23_RS02555	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
HAV23_RS02560	ENOG4105ZU5	s-layer protein
HAV23_RS02565	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HAV23_RS02585	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HAV23_RS02600	ENOG4107R1I	NAD-dependent malic enzyme
HAV23_RS02610	ENOG4107RT4	flavin reductase domain protein
HAV23_RS02625	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
HAV23_RS02630	ENOG4105EHG	Permease protein
HAV23_RS02635	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HAV23_RS02665	ENOG4105CGZ	zinc metallopeptidase
HAV23_RS02675	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
HAV23_RS02705	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HAV23_RS02710	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HAV23_RS02715	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
HAV23_RS02720	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HAV23_RS02730	ENOG4108ZAF	Molybdopterin
HAV23_RS02735	ENOG4105KIP	Thioesterase
HAV23_RS02745	ENOG4106TNF	Periplasmic binding protein
HAV23_RS02755	ENOG4107T5V	SNARE associated Golgi
HAV23_RS02760	ENOG4107YBY	Hydrolase
HAV23_RS02770	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HAV23_RS02780	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HAV23_RS02785	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HAV23_RS02790	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
HAV23_RS02795	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HAV23_RS02810	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
HAV23_RS02825	ENOG4105EBR	Carboxylesterase
HAV23_RS02830	ENOG4105C9Q	fumarate hydratase class II
HAV23_RS02850	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HAV23_RS02855	ENOG4108Z6B	deaminase
HAV23_RS02870	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HAV23_RS02875	ENOG4105CA9	Pyruvate kinase
HAV23_RS02880	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HAV23_RS02885	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HAV23_RS02890	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HAV23_RS02900	ENOG4108Z4K	mutator MutT protein
HAV23_RS02905	ENOG4108NGU	Transcriptional regulator
HAV23_RS02910	ENOG4105E8R	UPF0173 metal-dependent hydrolase
HAV23_RS02915	ENOG4105C8B	TIGR00159 family
HAV23_RS02925	ENOG41073R8	VanW family
HAV23_RS02935	ENOG4105ECR	NmrA family
HAV23_RS02940	ENOG4105FA0	parb-like partition protein
HAV23_RS02945	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
HAV23_RS02950	ENOG4107YI1	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HAV23_RS02960	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HAV23_RS03010	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HAV23_RS03015	ENOG41073R8	VanW family
HAV23_RS03020	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HAV23_RS03025	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HAV23_RS03035	ENOG4107SUU	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
HAV23_RS03040	ENOG4105CPP	Dehydrogenase, E1 component
HAV23_RS03050	ENOG4105C7S	Dehydrogenase
HAV23_RS03065	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HAV23_RS03070	ENOG4105EUJ	GTP cyclohydrolase i
HAV23_RS03080	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HAV23_RS03085	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HAV23_RS03115	ENOG4105DTQ	mandelate racemase muconate lactonizing
HAV23_RS03140	ENOG4105DR4	Methyltransferase
HAV23_RS03175	ENOG4105DKK	Benzoate
HAV23_RS03185	ENOG4105D9P	serine threonine protein kinase
HAV23_RS03205	ENOG4108RCR	degv family
HAV23_RS03210	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
HAV23_RS03215	ENOG4108I5C	dEAD DEAH box helicase
HAV23_RS03260	ENOG4108FWR	Involved in acetate metabolism (By similarity)
HAV23_RS03270	ENOG4105ECB	domain protein
HAV23_RS03270	ENOG4105ECB	domain protein
HAV23_RS03275	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HAV23_RS03280	ENOG4105F9E	Shikimate 5-dehydrogenase
HAV23_RS03285	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HAV23_RS03295	ENOG4105DBV	ornithine carbamoyltransferase
HAV23_RS03310	ENOG4105C7S	Dehydrogenase
HAV23_RS03320	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HAV23_RS03325	ENOG4105K46	50S ribosomal protein l27
HAV23_RS03330	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HAV23_RS03335	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HAV23_RS03375	ENOG4105BZ1	(ABC) transporter
HAV23_RS03380	ENOG4105BZ1	(ABC) transporter
HAV23_RS03390	ENOG41082AW	Binds together with S18 to 16S ribosomal RNA (By similarity)
HAV23_RS03395	ENOG4107YH6	single-stranded DNA-binding protein
HAV23_RS03400	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HAV23_RS03405	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HAV23_RS03430	ENOG4107QI1	Mate efflux family protein
HAV23_RS03435	ENOG4107R13	MMPL domain protein
HAV23_RS03445	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
HAV23_RS03450	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HAV23_RS03460	ENOG4105CHR	reductase
HAV23_RS03475	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HAV23_RS03480	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HAV23_RS03485	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HAV23_RS03490	ENOG4105C79	DNA protecting protein DprA
HAV23_RS03500	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HAV23_RS03505	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
HAV23_RS03520	ENOG4105DVC	DnaJ domain protein
HAV23_RS03525	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
HAV23_RS03530	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HAV23_RS03540	ENOG4105CSA	Coproporphyrinogen iii oxidase
HAV23_RS03550	ENOG4105CSR	polyphosphate kinase 2
HAV23_RS03585	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HAV23_RS03605	ENOG4105F8V	Hydrolase, tatD family
HAV23_RS03620	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HAV23_RS03625	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HAV23_RS03635	ENOG4105C9B	Cysteine desulfurase
HAV23_RS03645	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HAV23_RS03655	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HAV23_RS03660	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HAV23_RS03675	ENOG4105DBI	uridine monophosphokinase
HAV23_RS03695	ENOG4105BZ1	(ABC) transporter
HAV23_RS03705	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HAV23_RS03715	ENOG4105M03	Domain of unknown function (DUF955)
HAV23_RS03720	ENOG4105EEI	dihydropteroate synthase
HAV23_RS03730	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HAV23_RS03750	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HAV23_RS03755	ENOG4108UJD	30S ribosomal protein S9
HAV23_RS03770	ENOG4105D7V	transposase
HAV23_RS03775	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HAV23_RS03780	ENOG4105EMN	RNA polymerase sigma factor
HAV23_RS03810	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HAV23_RS03815	ENOG4108UB4	uncharacterized protein ygjQ
HAV23_RS03825	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HAV23_RS03860	ENOG4105CRQ	synthase (Component I)
HAV23_RS03870	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HAV23_RS03875	ENOG41080DW	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HAV23_RS03905	ENOG4105CJ1	ABC, transporter
HAV23_RS03925	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
HAV23_RS03935	ENOG4105D64	Mechanosensitive ion channel
HAV23_RS03955	ENOG4107QI6	Cysteine desulfurase
HAV23_RS03965	ENOG4105KHC	sulfurtransferase
HAV23_RS03985	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
HAV23_RS03990	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
HAV23_RS03995	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
HAV23_RS04000	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
HAV23_RS04010	ENOG4105C8V	SAICAR synthetase
HAV23_RS04020	ENOG4105NWN	ApaG protein
HAV23_RS04030	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HAV23_RS04035	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HAV23_RS04055	ENOG4105C88	aminopeptidase
HAV23_RS04060	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
HAV23_RS04065	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HAV23_RS04075	ENOG410667J	hydrolase
HAV23_RS04100	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HAV23_RS04110	ENOG41084ZW	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HAV23_RS04125	ENOG4105UIB	(ABC) transporter
HAV23_RS04135	ENOG4105C02	permease
HAV23_RS04160	ENOG4107QSN	dihydrolipoamide acetyltransferase
HAV23_RS04165	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HAV23_RS04170	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HAV23_RS04180	ENOG4105DJ2	Major Facilitator Superfamily
HAV23_RS04185	ENOG4105M6F	mutator MutT protein
HAV23_RS04190	ENOG4105DP9	ABC transporter
HAV23_RS04220	ENOG4105BZU	Histidine kinase
HAV23_RS04235	ENOG4107UV6	ribonuclease Z
HAV23_RS04275	ENOG4105CVJ	phosphoglycerate mutase
HAV23_RS04280	ENOG4105NAU	thioesterase Superfamily protein
HAV23_RS04285	ENOG4105CP9	extracellular ligand-binding receptor
HAV23_RS04290	ENOG4105C32	Amino acid ABC transporter (Permease)
HAV23_RS04295	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HAV23_RS04300	ENOG4105C0Z	ABC transporter
HAV23_RS04305	ENOG4108IV0	ABC, transporter
HAV23_RS04320	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HAV23_RS04345	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HAV23_RS04355	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HAV23_RS04365	ENOG4108R1E	Serine threonine protein phosphatase 1
HAV23_RS04375	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HAV23_RS04390	ENOG4105C0H	protease
HAV23_RS04400	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HAV23_RS04410	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HAV23_RS04415	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HAV23_RS04420	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HAV23_RS04435	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HAV23_RS04440	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HAV23_RS04445	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HAV23_RS04450	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HAV23_RS04455	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HAV23_RS04460	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HAV23_RS04465	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HAV23_RS04470	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HAV23_RS04475	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HAV23_RS04480	ENOG4108CHD	50s ribosomal protein l29
HAV23_RS04485	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HAV23_RS04490	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HAV23_RS04495	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HAV23_RS04500	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HAV23_RS04510	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HAV23_RS04520	ENOG4105C0H	protease
HAV23_RS04545	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HAV23_RS04565	ENOG4105CEY	Amp-dependent synthetase and ligase
HAV23_RS04585	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HAV23_RS04595	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HAV23_RS04600	ENOG41081YG	arsenite oxidase, small subunit
HAV23_RS04605	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
HAV23_RS04615	ENOG4107QX9	Thiol disulfide interChange protein
HAV23_RS04620	ENOG4105DA4	cytochrome c-type biogenesis protein
HAV23_RS04630	ENOG41060IM	Heme exporter protein
HAV23_RS04635	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HAV23_RS04640	ENOG4105D9P	serine threonine protein kinase
HAV23_RS04655	ENOG4105CGK	Exodeoxyribonuclease III
HAV23_RS04670	ENOG4108UJU	UPF0301 protein
HAV23_RS04675	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HAV23_RS04695	ENOG4105CPF	Cell wall formation (By similarity)
HAV23_RS04700	ENOG4105DEF	Extracellular solute-binding protein, family 5
HAV23_RS04705	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HAV23_RS04715	ENOG4105DVY	radical SAM domain protein
HAV23_RS04735	ENOG4108XHF	Pfam:DUF178
HAV23_RS04745	ENOG4105CRK	lysyL-tRNA synthetase
HAV23_RS04770	ENOG4105EJQ	L-serine dehydratase
HAV23_RS04795	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HAV23_RS04815	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HAV23_RS04835	ENOG4105DP4	dak2 domain fusion protein ylov
HAV23_RS04850	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HAV23_RS04855	ENOG410816E	Phosphotransferase enzyme family
HAV23_RS04860	ENOG4105D94	Major Facilitator Superfamily
HAV23_RS04870	ENOG4108J2R	molybdopterin oxidoreductase
HAV23_RS04885	ENOG4105CNU	cell division protein FtsK
HAV23_RS04890	ENOG4108UKM	mov34 mpn pad-1 family protein
HAV23_RS04895	ENOG4105DU0	nucleoside hydrolase
HAV23_RS04910	ENOG4105CIG	ABC transporter
HAV23_RS04940	ENOG4105C3M	thioredoxin reductase
HAV23_RS04990	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
HAV23_RS05000	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HAV23_RS05010	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HAV23_RS05015	ENOG4107UH2	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HAV23_RS05035	ENOG4108YRB	methyltransferase
HAV23_RS05040	ENOG4105WH1	Two component transcriptional regulator luxr family
HAV23_RS05065	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HAV23_RS05080	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HAV23_RS05085	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HAV23_RS05095	ENOG4105CZX	twitching motility protein
HAV23_RS05105	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HAV23_RS05120	ENOG4107QV3	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HAV23_RS05135	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
HAV23_RS05140	ENOG4105C5F	glutamine synthetase
HAV23_RS05155	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HAV23_RS05185	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HAV23_RS05190	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
HAV23_RS05205	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HAV23_RS05210	ENOG4105K4I	Scp-like extracellular
HAV23_RS05215	ENOG4105BZU	Histidine kinase
HAV23_RS05220	ENOG4105DCG	PHP domain protein
HAV23_RS05235	ENOG4107RVV	histidinol phosphate phosphatase, hisj family
HAV23_RS05240	ENOG4108URH	decarboxylase
HAV23_RS05255	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HAV23_RS05260	ENOG4105C5H	ABC transporter
HAV23_RS05285	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
HAV23_RS05300	ENOG4105K5B	UPF0225 protein
HAV23_RS05310	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HAV23_RS05320	ENOG4105D60	lipoprotein releasing system transmembrane protein
HAV23_RS05330	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
HAV23_RS05345	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HAV23_RS05350	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HAV23_RS05355	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HAV23_RS05380	ENOG4105CJR	Integral membrane protein (MviN
HAV23_RS05390	ENOG4105EPR	degv family
HAV23_RS05395	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HAV23_RS05400	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HAV23_RS05425	ENOG4105C0B	DNA polymerase III (alpha subunit)
HAV23_RS05430	ENOG4106H3A	restriction
HAV23_RS05445	ENOG4105E2Y	ABC, transporter
HAV23_RS05450	ENOG4107Y9U	Membrane
HAV23_RS05460	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HAV23_RS05600	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HAV23_RS05605	ENOG4105CHR	reductase
HAV23_RS05630	ENOG4106855	Competence protein
HAV23_RS05635	ENOG4105CDU	Replicative dna helicase
HAV23_RS05645	ENOG4105C1G	acyl-Coa dehydrogenase
HAV23_RS05665	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HAV23_RS05670	ENOG4105K4P	CoA-binding domain protein
HAV23_RS05680	ENOG4105C31	Tryptophanyl-tRNA synthetase
HAV23_RS05700	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HAV23_RS05705	ENOG4107FKK	extracellular solute-binding protein family 1
HAV23_RS05710	ENOG4105D56	permease protein
HAV23_RS05720	ENOG4105EAB	amino acid AbC transporter
HAV23_RS05725	ENOG4105E5Q	amino acid AbC transporter
HAV23_RS05735	ENOG4105C7B	Threonine dehydratase
HAV23_RS05740	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HAV23_RS05775	ENOG4105JFG	SpoIID LytB domain protein
HAV23_RS05790	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HAV23_RS05830	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HAV23_RS05835	ENOG4105CIY	formyltetrahydrofolate deformylase
HAV23_RS05845	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HAV23_RS05850	ENOG4106H3A	restriction
HAV23_RS05885	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HAV23_RS05900	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HAV23_RS05925	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HAV23_RS05930	ENOG4105CVJ	phosphoglycerate mutase
HAV23_RS05935	ENOG4108FWV	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HAV23_RS05945	ENOG4105BZU	Histidine kinase
HAV23_RS05950	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HAV23_RS05955	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HAV23_RS05965	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HAV23_RS05985	ENOG4105EIG	urea carboxylase-associated protein 1
HAV23_RS05995	ENOG4107RSM	transcriptional regulator
HAV23_RS06015	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HAV23_RS06020	ENOG4105F8C	transglutaminase domain-containing protein
HAV23_RS06025	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HAV23_RS06040	ENOG4108YYH	Nadph-dependent fmn reductase
HAV23_RS06050	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HAV23_RS06055	ENOG4105DFU	Cell wall formation (By similarity)
HAV23_RS06060	ENOG4107QWW	Cell wall formation (By similarity)
HAV23_RS06065	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
HAV23_RS06070	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HAV23_RS06095	ENOG4105CTQ	phosphohexokinase
HAV23_RS06125	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HAV23_RS06135	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HAV23_RS06140	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HAV23_RS06155	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HAV23_RS06160	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HAV23_RS06180	ENOG4105EEQ	Na H antiporter
HAV23_RS06235	ENOG410839S	Toxic component of a toxin-antitoxin (TA) module (By similarity)
HAV23_RS06255	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HAV23_RS06285	ENOG4105CDH	Citrulline--aspartate ligase
HAV23_RS06305	ENOG4105CH7	arginosuccinase
HAV23_RS06330	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
HAV23_RS06335	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HAV23_RS06370	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HAV23_RS06400	ENOG4105EBX	v-type atpase
HAV23_RS06410	ENOG4106287	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HAV23_RS06415	ENOG41089ID	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HAV23_RS06420	ENOG410704R	Produces ATP from ADP in the presence of a proton gradient across the membrane
HAV23_RS06425	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
HAV23_RS06430	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
HAV23_RS06435	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HAV23_RS06450	ENOG4105GSQ	TM1410 hypothetical-related protein
HAV23_RS06480	ENOG4108IAJ	Nad-dependent epimerase dehydratase
HAV23_RS06490	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HAV23_RS06510	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HAV23_RS06515	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
HAV23_RS06520	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HAV23_RS06550	ENOG4106YGA	NADH dehydrogenase (quinone)
HAV23_RS06560	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
HAV23_RS06565	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HAV23_RS06575	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HAV23_RS06580	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HAV23_RS06620	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
HAV23_RS06650	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HAV23_RS06660	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
HAV23_RS06665	ENOG4108CHF	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
HAV23_RS06680	ENOG4105KVY	Required for disulfide bond formation in some proteins (By similarity)
HAV23_RS06685	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HAV23_RS06695	ENOG4105BZN	citrate synthase
HAV23_RS06730	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HAV23_RS06735	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HAV23_RS06785	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HAV23_RS06790	ENOG4107ZC0	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HAV23_RS06795	ENOG4105D49	3-dehydroquinate synthase
HAV23_RS06800	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HAV23_RS06810	ENOG4108SA1	esterase
HAV23_RS06820	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HAV23_RS06825	ENOG4105KXX	peptidase s58 dmpa
HAV23_RS06830	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HAV23_RS06835	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HAV23_RS06860	ENOG4105C6T	cysteine synthase
HAV23_RS06865	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HAV23_RS06875	ENOG4107QMU	Mate efflux family protein
HAV23_RS06880	ENOG4105NAE	bifunctional deaminase-reductase domain protein
HAV23_RS06885	ENOG4105C8Y	Acetylornithine aminotransferase
HAV23_RS06935	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HAV23_RS06940	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HAV23_RS06945	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HAV23_RS06950	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HAV23_RS06975	ENOG4105C26	Dehydrogenase
HAV23_RS06980	ENOG41062BK	proline dehydrogenase
HAV23_RS06985	ENOG4107XBN	GntR Family Transcriptional Regulator
HAV23_RS07005	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
HAV23_RS07020	ENOG4105CHR	reductase
HAV23_RS07030	ENOG4107Y3Y	amidohydrolase
HAV23_RS07035	ENOG41082HT	Binds the 23S rRNA (By similarity)
HAV23_RS07040	ENOG4105SFS	phosphoesterase RecJ domain protein
HAV23_RS07045	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
HAV23_RS07060	ENOG4105EYW	Ion transport protein
HAV23_RS07070	ENOG4107SRH	Nad-dependent epimerase dehydratase
HAV23_RS07080	ENOG4105DGU	Histone deacetylase
HAV23_RS07120	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HAV23_RS07125	ENOG4108YYS	metal-dependent hydrolase (By similarity)
HAV23_RS07140	ENOG4105C7Z	Conserved Protein
HAV23_RS07145	ENOG4105E66	phosphoriboisomerase A
HAV23_RS07155	ENOG4105KA0	thioesterase Superfamily protein
HAV23_RS07160	ENOG41063SB	peptidase
HAV23_RS07175	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HAV23_RS07190	ENOG4105CXV	gliding motility protein
HAV23_RS07210	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
HAV23_RS07225	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HAV23_RS07230	ENOG4105BZU	Histidine kinase
HAV23_RS07240	ENOG4105FE1	phytoene synthase
HAV23_RS07255	ENOG4105I3K	Ferric uptake regulator, Fur family
HAV23_RS07265	ENOG4108Z9B	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HAV23_RS07270	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HAV23_RS07285	ENOG4107RST	alpha/beta hydrolase fold
HAV23_RS07290	ENOG4108IQK	o-acetylhomoserine
HAV23_RS07325	ENOG4105D65	subunit l
HAV23_RS07330	ENOG4105HC0	Na H antiporter
HAV23_RS07335	ENOG4108ZE9	Monovalent cation H antiporter subunit C
HAV23_RS07350	ENOG4105W4C	monovalent cation H antiporter subunit F
HAV23_RS07355	ENOG4105KJM	monovalent cation h antiporter subunit g
HAV23_RS07365	ENOG4108I7Y	domain protein
HAV23_RS07375	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HAV23_RS07380	ENOG4108S01	response regulator
HAV23_RS07385	ENOG4108TQ9	Histidine kinase
HAV23_RS07390	ENOG4108159	Pfam:UPF0005
HAV23_RS07405	ENOG4105FE9	pseudouridine synthase
HAV23_RS07425	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HAV23_RS07435	ENOG41086Q6	ribosome-binding factor A
HAV23_RS07450	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HAV23_RS07455	ENOG4105VEQ	Cold shock protein
HAV23_RS07475	ENOG41068JE	domain protein
HAV23_RS07480	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HAV23_RS07485	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HAV23_RS07490	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
HAV23_RS07495	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HAV23_RS07540	ENOG4105C1G	acyl-Coa dehydrogenase
HAV23_RS07555	ENOG4105CJ3	phosphate transporter
HAV23_RS07560	ENOG4108SDH	ABC, transporter
HAV23_RS07565	ENOG4105CJ1	ABC, transporter
HAV23_RS07575	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
HAV23_RS07590	ENOG4105EAH	synthase
HAV23_RS07600	ENOG4105KNI	merR family transcriptional Regulator
HAV23_RS07605	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HAV23_RS07610	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HAV23_RS07625	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
HAV23_RS07635	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HAV23_RS07640	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HAV23_RS07650	ENOG4105K63	Thioredoxin
HAV23_RS07660	ENOG4105DER	m42 family
HAV23_RS07685	ENOG4105E33	succinate dehydrogenase
HAV23_RS07690	ENOG4108J01	L-aspartate oxidase
HAV23_RS07715	ENOG4108JQ9	ABC transporter
HAV23_RS07720	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HAV23_RS07725	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HAV23_RS07735	ENOG4105C34	Pseudouridine synthase
HAV23_RS07745	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HAV23_RS07760	ENOG4105C3R	Methionine synthase
HAV23_RS07780	ENOG4105C10	Electron transfer flavoprotein
HAV23_RS07785	ENOG4105BZJ	Electron transfer flavoprotein
HAV23_RS07800	ENOG4105KR8	Inherit from COG: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HAV23_RS07810	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HAV23_RS07815	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
HAV23_RS07835	ENOG4105D82	Glutamate dehydrogenase
HAV23_RS07840	ENOG4105D82	Glutamate dehydrogenase
HAV23_RS07845	ENOG4106TD9	Diguanylate cyclase
HAV23_RS07850	ENOG4108Z4T	Peptidase M50
HAV23_RS07860	ENOG4105C0H	protease
HAV23_RS07865	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HAV23_RS07870	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
HAV23_RS07875	ENOG4105WH1	Two component transcriptional regulator luxr family
HAV23_RS07890	ENOG4108IJ8	ABC transporter
HAV23_RS07895	ENOG4105C5R	Aminotransferase
HAV23_RS07920	ENOG4108W63	CRP FNR family transcriptional regulator
HAV23_RS07925	ENOG4105D1F	ATP-binding protein
HAV23_RS07940	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HAV23_RS07945	ENOG4108Z18	K06886 hemoglobin
HAV23_RS07955	ENOG41080TC	multidrug resistance protein
HAV23_RS07960	ENOG4105KPY	Small multidrug resistance protein
HAV23_RS07965	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
HAV23_RS07970	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HAV23_RS07975	ENOG4105DTN	riboflavin biosynthesis protein ribF
HAV23_RS07985	ENOG4105E63	Pfam:DUF178
HAV23_RS07990	ENOG4105CJ1	ABC, transporter
HAV23_RS08005	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HAV23_RS08025	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HAV23_RS08030	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HAV23_RS08055	ENOG4105CQB	FAD linked oxidase domain protein
HAV23_RS08060	ENOG4106PMH	Extracellular solute-binding protein family 3
HAV23_RS08065	ENOG4105E5Q	amino acid AbC transporter
HAV23_RS08070	ENOG4108JCI	Transcriptional regulator
HAV23_RS08095	ENOG4108IV0	ABC, transporter
HAV23_RS08105	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HAV23_RS08110	ENOG4105C32	Amino acid ABC transporter (Permease)
HAV23_RS08120	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HAV23_RS08150	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HAV23_RS08185	ENOG4107XM9	(LipO)protein
HAV23_RS08195	ENOG4105C5S	asparaginyl-tRNA synthetase
HAV23_RS08240	ENOG4105EIN	peptidylprolyl cis-trans isomerase
HAV23_RS08265	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HAV23_RS08275	ENOG4108387	Peptidase E
HAV23_RS08285	ENOG4105CHU	acetyl-coa acetyltransferase
HAV23_RS08300	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HAV23_RS08330	ENOG4105CND	Glycosyl transferase, family 2
HAV23_RS08340	ENOG4105MS2	ribosomal subunit Interface protein
HAV23_RS08360	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HAV23_RS08375	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HAV23_RS08380	ENOG4105BZU	Histidine kinase
HAV23_RS08395	ENOG4105C31	Tryptophanyl-tRNA synthetase
HAV23_RS08410	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HAV23_RS08415	ENOG4105CVJ	phosphoglycerate mutase
HAV23_RS08430	ENOG4105C72	UPF0176 protein
HAV23_RS08445	ENOG4105C5H	ABC transporter
HAV23_RS08455	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HAV23_RS08460	ENOG4105CD3	dihydroorotase
HAV23_RS08475	ENOG4105CXT	aspartate transcarbamylase
HAV23_RS08480	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HAV23_RS08500	ENOG4107Y70	Heat shock protein
HAV23_RS08520	ENOG4105CTP	PilT protein domain protein
HAV23_RS08535	ENOG4105CKM	Branched-chain carboxylic acid kinase
HAV23_RS08550	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HAV23_RS08555	ENOG4105ZU5	s-layer protein
HAV23_RS08565	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HAV23_RS08590	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HAV23_RS08595	ENOG4105C01	Dihydroxy-acid dehydratase
HAV23_RS08600	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HAV23_RS08660	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HAV23_RS08675	ENOG4105NCW	Trka-c domain protein
HAV23_RS08680	ENOG4107S91	Sodium hydrogen exchanger
HAV23_RS08685	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HAV23_RS08690	ENOG4105E39	Enoyl-CoA hydratase
HAV23_RS08700	ENOG4105CD3	dihydroorotase
HAV23_RS08705	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
HAV23_RS08710	ENOG4107R9S	Malate synthase
HAV23_RS08715	ENOG4107HP6	Transcriptional regulator
HAV23_RS08745	ENOG4105VT2	5-hydroxyisourate hydrolase
HAV23_RS08750	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HAV23_RS08755	ENOG4105CZX	twitching motility protein
HAV23_RS08760	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HAV23_RS08780	ENOG4105E09	nadh pyrophosphatase
HAV23_RS08805	ENOG4107TBS	Shikimate dehydrogenase
HAV23_RS08810	ENOG4105BZU	Histidine kinase
HAV23_RS08855	ENOG4108IY2	MazG family
HAV23_RS08860	ENOG4105P8F	nudix hydrolase
HAV23_RS08870	ENOG4105EE5	Membrane protein terC
HAV23_RS08875	ENOG4105C02	permease
HAV23_RS08925	ENOG4108Z0Z	intracellular protease Pfpi family
HAV23_RS08955	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
HAV23_RS08965	ENOG4108FWV	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HAV23_RS08975	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HAV23_RS08995	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
HAV23_RS09000	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HAV23_RS09005	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HAV23_RS09025	ENOG4105CE1	Ferrous iron transport protein b
HAV23_RS09065	ENOG4107V8I	Glycosyl transferases group 1
HAV23_RS09130	ENOG4105CI0	Citrate lyase
HAV23_RS09145	ENOG4105D9P	serine threonine protein kinase
HAV23_RS09165	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HAV23_RS09170	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HAV23_RS09205	ENOG4105C1G	acyl-Coa dehydrogenase
HAV23_RS09235	ENOG4107U9K	TROVE domain-containing protein
HAV23_RS09265	ENOG4107R1M	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity)
HAV23_RS09285	ENOG4105C5S	asparaginyl-tRNA synthetase
HAV23_RS09295	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
HAV23_RS09310	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HAV23_RS09315	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HAV23_RS09320	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HAV23_RS09335	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HAV23_RS09345	ENOG4105D48	metallophosphoesterase
HAV23_RS09355	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HAV23_RS09375	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HAV23_RS09380	ENOG4105DEF	Extracellular solute-binding protein, family 5
HAV23_RS09390	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
HAV23_RS09400	ENOG4105K5M	30s ribosomal protein S16
HAV23_RS09415	ENOG4105CKW	Inner membrane protein yedI
HAV23_RS09430	ENOG4107QIV	Cytochrome c biogenesis protein
HAV23_RS09440	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HAV23_RS09450	ENOG4105D38	putrescine abc transporter
HAV23_RS09455	ENOG4107RUE	extracellular solute-binding protein family 1
HAV23_RS09465	ENOG4105EV4	Multidrug resistance protein mdtH
HAV23_RS09470	ENOG4105CN1	protease
HAV23_RS09475	ENOG4108A5Q	Binds directly to 16S ribosomal RNA (By similarity)
HAV23_RS09480	ENOG41086EC	Modulates RecA activity (By similarity)
HAV23_RS09490	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HAV23_RS09505	ENOG4105T2N	Domain of unknown function (DUF2382)
HAV23_RS09515	ENOG4108HNZ	carboxyl transferase
HAV23_RS09525	ENOG4105C1G	acyl-Coa dehydrogenase
HAV23_RS09545	ENOG4105S8Q	sugar efflux transporter
HAV23_RS09550	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HAV23_RS09560	ENOG4108QBX	(LipO)protein
HAV23_RS09570	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HAV23_RS09585	ENOG4107ZY0	Phenazine biosynthesis-like protein
HAV23_RS09595	ENOG4105D17	glycoside hydrolase, family 3 domain protein
HAV23_RS09600	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HAV23_RS09610	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HAV23_RS09620	ENOG4105CP7	Triose-phosphate isomerase
HAV23_RS09635	ENOG4105BZA	Phosphoglycerate kinase
HAV23_RS09640	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HAV23_RS09655	ENOG4105C9M	aspartyl-trna synthetase
HAV23_RS09665	ENOG4105CUT	histidyl-tRNA synthetase
HAV23_RS09670	ENOG4105C5R	Aminotransferase
HAV23_RS09680	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HAV23_RS09685	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HAV23_RS09690	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HAV23_RS09695	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
HAV23_RS09700	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HAV23_RS09705	ENOG4108UMI	ABC transporter, permease
HAV23_RS09710	ENOG4105D01	(LipO)protein
HAV23_RS09715	ENOG4105D01	(LipO)protein
HAV23_RS09725	ENOG4107SN7	NLP P60 protein
HAV23_RS09735	ENOG4105CBD	Diacylglycerol kinase
HAV23_RS09750	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
HAV23_RS09755	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
HAV23_RS09760	ENOG4105DFA	alanine racemase domain protein
HAV23_RS09790	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HAV23_RS09795	ENOG4105CG3	alpha amylase, catalytic region
HAV23_RS09800	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HAV23_RS09810	ENOG4105E0X	reductase
HAV23_RS09840	ENOG4105C3G	gtp-binding protein
HAV23_RS09845	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HAV23_RS09855	ENOG4105MJ2	Competence protein
HAV23_RS09885	ENOG4105EAH	synthase
HAV23_RS09910	ENOG4108N5B	2-phosphosulfolactate phosphatase
HAV23_RS09985	ENOG4108JQC	penicillin-binding protein 1A
HAV23_RS09990	ENOG4108KXV	response regulator
HAV23_RS10000	ENOG4107U4Q	acetylglutamate kinase
HAV23_RS10015	ENOG4105X0R	protein from nitrogen regulatory protein P-II
HAV23_RS10020	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HAV23_RS10030	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HAV23_RS10040	ENOG4105CHU	acetyl-coa acetyltransferase
HAV23_RS10055	ENOG4105C12	Phosphoribosylglycinamide synthetase
HAV23_RS10070	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HAV23_RS10075	ENOG4105CHW	UPF0052 protein
HAV23_RS10090	ENOG4107T3P	ABC, transporter
HAV23_RS10100	ENOG4105C59	p-type ATPase
HAV23_RS10120	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
HAV23_RS10125	ENOG4107ZZY	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HAV23_RS10140	ENOG41067MG	lrgb family
HAV23_RS10150	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
HAV23_RS10155	ENOG4105C87	Aminotransferase class I and II
HAV23_RS10175	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HAV23_RS10185	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HAV23_RS10215	ENOG4105EMU	Dehydrogenase
HAV23_RS10220	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HAV23_RS10235	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HAV23_RS10250	ENOG41087YS	Phage shock protein A
HAV23_RS10260	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HAV23_RS10295	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HAV23_RS10320	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HAV23_RS10325	ENOG4108KGH	TRANSCRIPTIONal
HAV23_RS10330	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
HAV23_RS10345	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HAV23_RS10350	ENOG4107WFQ	NADH-quinone oxidoreductase, chain M
HAV23_RS10360	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HAV23_RS10365	ENOG41087XN	oxidoreductase
HAV23_RS10370	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HAV23_RS10375	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HAV23_RS10385	ENOG4107EEP	NADH dehydrogenase (quinone) (EC 1.6.99.5)
HAV23_RS10390	ENOG4105GKE	subunit e
HAV23_RS10400	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HAV23_RS10405	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HAV23_RS10410	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HAV23_RS10415	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HAV23_RS10420	ENOG4105DZP	Membrane-associated zinc metalloprotease
HAV23_RS10425	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HAV23_RS10430	ENOG4105KNE	Phosphatidate cytidylyltransferase
HAV23_RS10435	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HAV23_RS10440	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HAV23_RS10445	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HAV23_RS10450	ENOG4105CE9	30S ribosomal protein S2
HAV23_RS10465	ENOG4105C7K	acetolactate synthase
HAV23_RS10480	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HAV23_RS10490	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HAV23_RS10495	ENOG4105II7	pyrroline-5-carboxylate reductase
HAV23_RS10505	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HAV23_RS10510	ENOG4108RVA	ribokinase
HAV23_RS10515	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HAV23_RS10525	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HAV23_RS10560	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HAV23_RS10565	ENOG4105E5G	Alpha beta hydrolase fold
HAV23_RS10570	ENOG4108Z9K	Osmotically inducible protein
HAV23_RS10580	ENOG4108HMX	isocitrate dehydrogenase (NADP)
HAV23_RS10590	ENOG4107QX3	carboxylase
HAV23_RS10600	ENOG4105C1G	acyl-Coa dehydrogenase
HAV23_RS10610	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HAV23_RS10625	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
HAV23_RS10630	ENOG4105CAK	Cell division ATP-binding protein ftsE
HAV23_RS10635	ENOG4105CN1	protease
HAV23_RS10645	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HAV23_RS10650	ENOG4105EPR	degv family
HAV23_RS10655	ENOG4105CPK	Glycosyl transferase (Group 1
HAV23_RS10660	ENOG4105BZU	Histidine kinase
HAV23_RS10670	ENOG4105WH1	Two component transcriptional regulator luxr family
HAV23_RS10680	ENOG4107TE5	Lipid kinase
HAV23_RS10685	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HAV23_RS10690	ENOG4105ESV	Glycosyl transferase, family 4
HAV23_RS10695	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HAV23_RS10705	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HAV23_RS10725	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HAV23_RS10735	ENOG4107QRA	Extracellular solute-binding protein, family 5
HAV23_RS10740	ENOG4105EEM	helicase
HAV23_RS10745	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HAV23_RS10750	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
HAV23_RS10765	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HAV23_RS10775	ENOG4105XT2	Transcriptional regulator
HAV23_RS10790	ENOG4105CJ1	ABC, transporter
HAV23_RS10810	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HAV23_RS10815	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HAV23_RS10825	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HAV23_RS10850	ENOG4108J5G	6-phosphogluconate dehydrogenase
HAV23_RS10895	ENOG4105ETX	regulatoR
HAV23_RS10915	ENOG4105ERH	Fumarylacetoacetate hydrolase
HAV23_RS10920	ENOG4108JFJ	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HAV23_RS10940	ENOG4108S93	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HAV23_RS10955	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
HAV23_RS10960	ENOG41073R8	VanW family
HAV23_RS10965	ENOG4105CHR	reductase
HAV23_RS10970	ENOG4105K59	histidine triad (HIT) protein
HAV23_RS10975	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
HAV23_RS10990	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HAV23_RS10995	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HAV23_RS11000	ENOG4105DPN	Oligoendopeptidase f
HAV23_RS11005	ENOG4107TXC	Transcriptional regulator
HAV23_RS11010	ENOG4105BZU	Histidine kinase
HAV23_RS11045	ENOG4105C5H	ABC transporter
HAV23_RS11050	ENOG41061CK	Antibiotic biosynthesis monooxygenase
HAV23_RS11055	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
HAV23_RS11060	ENOG4108WBT	adenosyltransferase
HAV23_RS11095	ENOG4107RU9	Transcriptional regulator, Crp Fnr family
HAV23_RS11100	ENOG41074B2	UPF0747 protein
HAV23_RS11105	ENOG4105CDA	abc transporter atp-binding protein
HAV23_RS11110	ENOG4105H1G	trap transporter solute receptor taxi family
HAV23_RS11120	ENOG4105D7V	transposase
HAV23_RS11140	ENOG4108J8Z	aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein
HAV23_RS11145	ENOG4105C0P	Mg chelatase subunit ChlI
HAV23_RS11160	ENOG4105DGW	oligopeptidase A
HAV23_RS11170	ENOG4105MCT	stage V sporulation protein S
HAV23_RS11175	ENOG4105CPQ	Dehydrogenase
HAV23_RS11190	ENOG4108UIH	futalosine nucleosidase
HAV23_RS11210	ENOG4105CZN	Potassium uptake protein
HAV23_RS11215	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HAV23_RS11220	ENOG4105C8N	cysteinyl-tRNA synthetase
HAV23_RS11235	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HAV23_RS11240	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HAV23_RS11265	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HAV23_RS11270	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HAV23_RS11275	ENOG4105CWE	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HAV23_RS11295	ENOG4107QJE	Chromosome Partitioning Protein
HAV23_RS11305	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HAV23_RS11315	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
HAV23_RS11320	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HAV23_RS11330	ENOG4105CEY	Amp-dependent synthetase and ligase
HAV23_RS11340	ENOG4105DR4	Methyltransferase
HAV23_RS11345	ENOG4108UYE	Lactoylglutathione lyase
HAV23_RS11350	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HAV23_RS11360	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HAV23_RS11385	ENOG4105ECY	inositol monophosphatase
HAV23_RS11395	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
HAV23_RS11410	ENOG4105C2M	dna polymerase I
HAV23_RS11420	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
HAV23_RS11435	ENOG4105DEF	Extracellular solute-binding protein, family 5
HAV23_RS11465	ENOG4105D82	Glutamate dehydrogenase
HAV23_RS11510	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
HAV23_RS11515	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
HAV23_RS11525	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HAV23_RS11530	ENOG4105CQB	FAD linked oxidase domain protein
HAV23_RS11555	ENOG4105CGH	5'-nucleotidase
HAV23_RS11585	ENOG4105C89	phosphohexose isomerase
HAV23_RS11610	ENOG4105DJT	lAO AO transport system ATPase
HAV23_RS11620	ENOG41068JE	domain protein
HAV23_RS11630	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
HAV23_RS11645	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
HAV23_RS11650	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HAV23_RS11660	ENOG4105C0H	protease
HAV23_RS11670	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HAV23_RS11675	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HAV23_RS11700	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
HAV23_RS11710	ENOG4105DDQ	anthranilate synthase
HAV23_RS11715	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HAV23_RS11725	ENOG4107X7R	Pyrrolo-quinoline quinone
HAV23_RS11735	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HAV23_RS11770	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HAV23_RS11795	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HAV23_RS11800	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HAV23_RS11810	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HAV23_RS11820	ENOG4105C34	Pseudouridine synthase
HAV23_RS11830	ENOG4105CRQ	synthase (Component I)
HAV23_RS11865	ENOG410836C	Required for maturation of 30S ribosomal subunits (By similarity)
HAV23_RS11870	ENOG4105CHV	Transcription elongation factor NusA
HAV23_RS11880	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HAV23_RS11885	ENOG41068WN	
HAV23_RS11925	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
HAV23_RS11930	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HAV23_RS11940	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HAV23_RS11945	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HAV23_RS11960	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
HAV23_RS11970	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HAV23_RS11985	ENOG4105E5J	UV damage endonuclease
HAV23_RS12000	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HAV23_RS12005	ENOG4105C8F	Beta-lactamase domain protein
HAV23_RS12010	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
HAV23_RS12020	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HAV23_RS12025	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HAV23_RS12060	ENOG4105DR4	Methyltransferase
HAV23_RS12065	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HAV23_RS12070	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HAV23_RS12080	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HAV23_RS12110	ENOG4108ME1	Peptidase M55 D-aminopeptidase
HAV23_RS12125	ENOG4105VUN	Transcriptional regulator
HAV23_RS12135	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HAV23_RS12140	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HAV23_RS12170	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HAV23_RS12175	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HAV23_RS12190	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HAV23_RS12195	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HAV23_RS12205	ENOG4105M08	Membrane
HAV23_RS12210	ENOG4108V6E	Cell division protein mraZ
HAV23_RS12215	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HAV23_RS12225	ENOG4105CJN	penicillin-binding protein
HAV23_RS12240	ENOG4105DTQ	mandelate racemase muconate lactonizing
HAV23_RS12255	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HAV23_RS12275	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HAV23_RS12285	ENOG4108UT2	hemolysin iii
HAV23_RS12305	ENOG4105ETE	Transcriptional regulator (LacI family
HAV23_RS12335	ENOG4107S5I	aldo keto reductase
HAV23_RS12345	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HAV23_RS12355	ENOG4105EW9	transcriptional regulator AsnC family
HAV23_RS12360	ENOG4105DCF	alanine dehydrogenase
HAV23_RS12375	ENOG4105D1H	recombination factor protein RarA
HAV23_RS12400	ENOG4107SID	ATP-dependent exodnase (exonuclease v)
HAV23_RS12420	ENOG4105DAA	L-lactate
HAV23_RS12425	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HAV23_RS12430	ENOG4107QR9	Iron-sulfur cluster binding protein
HAV23_RS12435	ENOG41080R8	Conserved Protein
HAV23_RS12440	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HAV23_RS12455	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HAV23_RS12465	ENOG4105F6J	Alpha beta hydrolase fold
HAV23_RS12495	ENOG4107RH8	nuclease SbcCD subunit D
HAV23_RS12500	ENOG4105EYH	Exonuclease
HAV23_RS12525	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HAV23_RS12540	ENOG4107RHR	regulatoR
HAV23_RS12555	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HAV23_RS12565	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HAV23_RS12575	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HAV23_RS12580	ENOG41083PU	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HAV23_RS12585	ENOG4105CHR	reductase
HAV23_RS12595	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HAV23_RS12600	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HAV23_RS12605	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HAV23_RS12610	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HAV23_RS12615	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HAV23_RS12645	ENOG4105DEF	Extracellular solute-binding protein, family 5
HAV23_RS12670	ENOG4105CHU	acetyl-coa acetyltransferase
HAV23_RS12695	ENOG4105D7V	transposase
HAV23_RS12705	ENOG4107QHF	type ii secretion system protein e
HAV23_RS12710	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
HAV23_RS12715	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HAV23_RS12720	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HAV23_RS12735	ENOG4105RTX	GreA GreB family elongation factor
HAV23_RS12745	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HAV23_RS12750	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HAV23_RS12755	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HAV23_RS12765	ENOG4105C98	muts2 protein
HAV23_RS12785	ENOG4105CGD	Nad-dependent epimerase dehydratase
HAV23_RS12795	ENOG4105C3M	thioredoxin reductase
HAV23_RS12805	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HAV23_RS12810	ENOG4107104	thymidine kinase
HAV23_RS12820	ENOG4105EPR	degv family
HAV23_RS12845	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
HAV23_RS12865	ENOG4105D8X	mechanosensitive ion channel
HAV23_RS12870	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HAV23_RS12880	ENOG4105CH6	catalase
HAV23_RS12885	ENOG410829K	Lysine exporter protein (Lyse ygga)
HAV23_RS12910	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HAV23_RS12915	ENOG410868C	50s ribosomal protein l35
HAV23_RS12930	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HAV23_RS12935	ENOG4105VB6	UPF0109 protein
HAV23_RS12940	ENOG4106GF2	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HAV23_RS12945	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HAV23_RS12955	ENOG4105CBT	Fructose-1,6-bisphosphatase
HAV23_RS13000	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HAV23_RS13020	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HAV23_RS13025	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HAV23_RS13075	ENOG4105PMW	Domain of unknown function (DUF1990)
HAV23_RS13095	ENOG4107QJE	Chromosome Partitioning Protein
HAV23_RS13110	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HAV23_RS13115	ENOG4108VZM	50s ribosomal protein L10
HAV23_RS13120	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HAV23_RS13125	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HAV23_RS13130	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HAV23_RS13135	ENOG410683Z	Preprotein translocase SecE subunit
HAV23_RS13140	ENOG4105W0E	50S ribosomal protein L33
HAV23_RS13145	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HAV23_RS13170	ENOG4105BZ1	(ABC) transporter
HAV23_RS13175	ENOG4105BZ1	(ABC) transporter
HAV23_RS13185	ENOG4105DPN	Oligoendopeptidase f
HAV23_RS13210	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
HAV23_RS13230	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HAV23_RS13245	ENOG410803B	Involved in the transcription termination process (By similarity)
HAV23_RS13255	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HAV23_RS13260	ENOG4105DIH	basic membrane
HAV23_RS13265	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HAV23_RS13270	ENOG4107S85	alpha-2-macroglobulin domain protein
HAV23_RS13295	ENOG4105P4J	Allophanate hydrolase, subunit 1
HAV23_RS13300	ENOG4105E7W	lamb ycsf family protein
HAV23_RS13305	ENOG4108QT4	peptidase S8 and S53, subtilisin, kexin, sedolisin
HAV23_RS13315	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HAV23_RS13320	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
HAV23_RS13330	ENOG4107QP3	malate synthase g
HAV23_RS13335	ENOG4105C6K	Malic enzyme
HAV23_RS13360	ENOG41079KZ	Major Facilitator Superfamily
HAV23_RS13365	ENOG4105CPN	adenine deaminase
HAV23_RS13385	ENOG4105CEY	Amp-dependent synthetase and ligase
HAV23_RS13400	ENOG4105C0Z	ABC transporter
HAV23_RS13405	ENOG4108IV0	ABC, transporter
HAV23_RS13410	ENOG4105CH6	catalase
HAV23_RS13425	ENOG4105JXB	ankyrin repeat-containing protein
HAV23_RS13430	ENOG4105DZS	Phenylacetate-CoA ligase
HAV23_RS13435	ENOG4107SQI	penicillin amidase
HAV23_RS13450	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HAV23_RS13455	ENOG4105CSU	acyl-Coa dehydrogenase
HAV23_RS13470	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HAV23_RS13475	ENOG4105DEF	Extracellular solute-binding protein, family 5
HAV23_RS13485	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HAV23_RS13490	ENOG4105KPV	Transcriptional regulator
HAV23_RS13505	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
HAV23_RS13515	ENOG4105C7W	Xanthine dehydrogenase
HAV23_RS13520	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
HAV23_RS13525	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
HAV23_RS13535	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
HAV23_RS13540	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
HAV23_RS13545	ENOG4105C7W	Xanthine dehydrogenase
HAV23_RS13585	ENOG4105EFA	4-hydroxyphenylacetate
HAV23_RS13590	ENOG4105E9Z	Nad-dependent epimerase dehydratase
HAV23_RS13620	ENOG4107S1E	Beta-lactamase
HAV23_RS13630	ENOG4105CS1	NAD(P)H quinone oxidoreductase
HAV23_RS13635	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HAV23_RS13645	ENOG4105FDP	GntR family transcriptional regulator
HAV23_RS13650	ENOG4107QRA	Extracellular solute-binding protein, family 5
HAV23_RS13660	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HAV23_RS13685	ENOG4105DKB	L-sorbosone dehydrogenase
HAV23_RS13690	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HAV23_RS13695	ENOG4105C4K	Nad synthetase
HAV23_RS13700	ENOG4105CHR	reductase
HAV23_RS13720	ENOG4105C1G	acyl-Coa dehydrogenase
HAV23_RS13755	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
HAV23_RS13770	ENOG4105C9X	ppx gppa phosphatase
HAV23_RS13775	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
HAV23_RS13780	ENOG4105C7N	Xanthine uracil vitamin C permease
HAV23_RS13790	ENOG4105BZU	Histidine kinase
HAV23_RS13795	ENOG4107QUY	Guanine deaminase
HAV23_RS13805	ENOG4105C7W	Xanthine dehydrogenase
HAV23_RS13815	ENOG4105C2W	permease
HAV23_RS13820	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
HAV23_RS13825	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HAV23_RS13835	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HAV23_RS13840	ENOG4105DWF	phosphomethylpyrimidine kinase
HAV23_RS13850	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HAV23_RS13860	ENOG4108UUC	Protein of unknown function DUF99
HAV23_RS13875	ENOG4105K63	Thioredoxin
HAV23_RS13895	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HAV23_RS13905	ENOG4105C8U	phosphate abc transporter
HAV23_RS13910	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
HAV23_RS13915	ENOG4105VPX	protein, conserved in bacteria
HAV23_RS13920	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HAV23_RS13925	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HAV23_RS13940	ENOG4105CGP	Urocanate hydratase
HAV23_RS13950	ENOG4105CYW	agmatinase
HAV23_RS13955	ENOG4105CI2	imidazolone-5-propionate hydrolase
HAV23_RS13960	ENOG4105C84	Histidine ammonia-lyase
HAV23_RS13980	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HAV23_RS13985	ENOG4105Y7M	Transcriptional regulator, TetR family
HAV23_RS14005	ENOG4105WJV	Binding-protein-dependent transport systems, inner membrane component
HAV23_RS14010	ENOG4108IJ8	ABC transporter
HAV23_RS14015	ENOG4107T5X	Binding-protein-dependent transport systems, inner membrane component
HAV23_RS14020	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
HAV23_RS14045	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
HAV23_RS14085	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HAV23_RS14090	ENOG4105DEN	Luciferase family
HAV23_RS14115	ENOG4105NVB	glycoside hydrolase, family 19
HAV23_RS14235	ENOG4105CF2	Mu-like prophage FluMu protein GP28
HAV23_RS14350	ENOG4105C59	p-type ATPase
HAV23_RS14370	ENOG4105CY0	Metallo-Beta-Lactamase
HAV23_RS14375	ENOG4105D6N	CoA-transferase, subunit a
HAV23_RS14390	ENOG4105K70	DNA-binding protein
HAV23_RS14395	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HAV23_RS14400	ENOG4107YEI	lmbE family
HAV23_RS14410	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HAV23_RS14445	ENOG4108RVA	ribokinase
HAV23_RS14450	ENOG4108IIH	CoA-transferase subunit B
HAV23_RS14455	ENOG4105CHU	acetyl-coa acetyltransferase
HAV23_RS14475	ENOG4105DG6	mannose-6-phosphate isomerase
HAV23_RS14500	ENOG4107ZIM	Dtdp-4-dehydrorhamnose 3,5-epimerase
HAV23_RS14505	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HAV23_RS14520	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HAV23_RS14525	ENOG4105H63	Glycosyl transferase, family 2
HAV23_RS14545	ENOG4105D3Q	Sugar transferase
HAV23_RS14555	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
HAV23_RS14565	ENOG4105C26	Dehydrogenase
HAV23_RS14570	ENOG4108JPW	Aminotransferase
HAV23_RS14595	ENOG4105PNM	synthesis protein
HAV23_RS14610	ENOG4108YZT	Adenosylcobinamide kinase
HAV23_RS14620	ENOG4105CGH	5'-nucleotidase
HAV23_RS14630	ENOG4107RIQ	Sulfate adenylate transferase
HAV23_RS14635	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
HAV23_RS14640	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
HAV23_RS14645	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HAV23_RS14675	ENOG4108M15	ABC transporter
HAV23_RS14690	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HAV23_RS14695	ENOG4105C26	Dehydrogenase
HAV23_RS14705	ENOG41089N3	Inherit from COG: cobyrinic Acid a,c-diamide synthase
HAV23_RS14735	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HAV23_RS14750	ENOG4105D7N	magnesium and cobalt transport protein CorA
HAV23_RS14770	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HAV23_RS14790	ENOG4105C8Q	Methyl-accepting chemotaxis
HAV23_RS14805	ENOG4108NVR	Methyl-accepting chemotaxis
HAV23_RS14815	ENOG4105M3Z	response regulator
HAV23_RS14820	ENOG4105BZ1	(ABC) transporter
HAV23_RS14825	ENOG4105C26	Dehydrogenase
HAV23_RS14845	ENOG410825M	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HAV23_RS14850	ENOG4105C26	Dehydrogenase
HAV23_RS14880	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
HAV23_RS14885	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
HAV23_RS14890	ENOG4105C1G	acyl-Coa dehydrogenase
HAV23_RS14925	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HAV23_RS14940	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HAV23_RS14955	ENOG4108IV0	ABC, transporter
HAV23_RS14960	ENOG4105C0Z	ABC transporter
HAV23_RS14970	ENOG4105C32	Amino acid ABC transporter (Permease)
HAV23_RS14975	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
HAV23_RS14980	ENOG4108YZ9	Urea amidohydrolase subunit gamma
HAV23_RS14985	ENOG4105CQM	Urea amidohydrolase subunit alpha
HAV23_RS14995	ENOG410833Q	hydrogenase nickel incorporation protein hypA
HAV23_RS15010	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HAV23_RS15015	ENOG4107S5F	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
HAV23_RS15020	ENOG41080CS	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HAV23_RS15025	ENOG4108JIK	carboxylase
HAV23_RS15030	ENOG4105CEY	Amp-dependent synthetase and ligase
HAV23_RS15050	ENOG4107TPS	domain protein
HAV23_RS15065	ENOG4105CA0	peroxidase
HAV23_RS15085	ENOG4105BZU	Histidine kinase
HAV23_RS15135	ENOG4105EHG	Permease protein
HAV23_RS15160	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HAV23_RS15165	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
HAV23_RS15170	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HAV23_RS15175	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
HAV23_RS15180	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
HAV23_RS15205	ENOG41089N3	Inherit from COG: cobyrinic Acid a,c-diamide synthase
HAV23_RS15220	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
HAV23_RS15265	ENOG4105BZG	amino acid carrier protein
HAV23_RS15275	ENOG4105EE5	Membrane protein terC
HAV23_RS15280	ENOG4105C37	(CBS) domain
HAV23_RS15285	ENOG4105C37	(CBS) domain
HAV23_RS15295	ENOG4108HUF	Transporter
HAV23_RS15305	ENOG4105DQ5	transport system permease protein
HAV23_RS15310	ENOG4108U1V	ABC transporter, permease
HAV23_RS15315	ENOG4105E0A	ABC, transporter
HAV23_RS15325	ENOG4105EEQ	Na H antiporter
HAV23_RS15360	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
HAV23_RS15370	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HAV23_RS15375	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HAV23_RS15455	ENOG4106TD9	Diguanylate cyclase
HAV23_RS15465	ENOG4105ETX	regulatoR
HAV23_RS15470	ENOG4105DHQ	Histidine kinase
HAV23_RS15505	ENOG4105BZU	Histidine kinase
HAV23_RS15510	ENOG4105WH1	Two component transcriptional regulator luxr family
HAV23_RS15515	ENOG4108QIU	Dehydrogenase
HAV23_RS15520	ENOG4105DTQ	mandelate racemase muconate lactonizing
HAV23_RS15525	ENOG4106PMH	Extracellular solute-binding protein family 3
HAV23_RS15535	ENOG4105MVE	transcriptional regulator
HAV23_RS15540	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HAV23_RS15545	ENOG4105DE4	1-phosphofructokinase
HAV23_RS15550	ENOG4105DM4	PTS System
HAV23_RS15570	ENOG4108QT4	peptidase S8 and S53, subtilisin, kexin, sedolisin
HAV23_RS15650	ENOG4105CMT	Dihydroxyacetone kinase
HAV23_RS15655	ENOG4108UTZ	Dihydroxyacetone kinase
HAV23_RS15660	ENOG4105VDH	Dihydroxyacetone kinase
HAV23_RS15675	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HAV23_RS15685	ENOG4105G6Z	alkaline phosphatase
HAV23_RS15705	ENOG4105DEF	Extracellular solute-binding protein, family 5
HAV23_RS15735	ENOG4105BZU	Histidine kinase
HAV23_RS15750	ENOG41089N3	Inherit from COG: cobyrinic Acid a,c-diamide synthase
HAV23_RS15765	ENOG4105BZU	Histidine kinase
HAV23_RS15775	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
HAV23_RS15780	ENOG4105FUA	antagonist
HAV23_RS15785	ENOG4107MMM	Anti-sigma-factor antagonist
HAV23_RS15875	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HAV23_RS15910	ENOG4105F8V	Hydrolase, tatD family
HAV23_RS15945	ENOG4108Q9V	regulatoR
HAV23_RS15950	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HAV23_RS15980	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)