locus-tag	class	description
HLB42_RS00005	ENOG4105DHQ	Histidine kinase
HLB42_RS00010	ENOG4105C79	DNA protecting protein DprA
HLB42_RS00025	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HLB42_RS00030	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HLB42_RS00035	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HLB42_RS00040	ENOG4105CA9	Pyruvate kinase
HLB42_RS00045	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HLB42_RS00065	ENOG41079SJ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HLB42_RS00070	ENOG4107UH2	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HLB42_RS00075	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HLB42_RS00085	ENOG4105CFG	Acts as a chaperone (By similarity)
HLB42_RS00090	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HLB42_RS00095	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
HLB42_RS00100	ENOG4105DVC	DnaJ domain protein
HLB42_RS00105	ENOG4105GR3	Histidine kinase
HLB42_RS00130	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HLB42_RS00160	ENOG4105BZU	Histidine kinase
HLB42_RS00190	ENOG4105D49	3-dehydroquinate synthase
HLB42_RS00215	ENOG4107QRG	dna polymerase iii
HLB42_RS00220	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HLB42_RS00250	ENOG4108ZIT	Ferredoxin, 2FE-2S
HLB42_RS00255	ENOG4107QP0	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HLB42_RS00260	ENOG4106TD9	Diguanylate cyclase
HLB42_RS00280	ENOG4105CEY	Amp-dependent synthetase and ligase
HLB42_RS00290	ENOG4108SA1	esterase
HLB42_RS00300	ENOG4108AQF	aminoglycoside N(3)-acetyltransferase
HLB42_RS00310	ENOG4105CPN	adenine deaminase
HLB42_RS00315	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HLB42_RS00325	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HLB42_RS00340	ENOG4108UKI	Enoyl-CoA hydratase
HLB42_RS00345	ENOG4106B0N	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HLB42_RS00375	ENOG4106633	50S ribosomal protein l28
HLB42_RS00380	ENOG41082JC	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HLB42_RS00385	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
HLB42_RS00405	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HLB42_RS00410	ENOG4105ZU5	s-layer protein
HLB42_RS00415	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
HLB42_RS00420	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HLB42_RS00435	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
HLB42_RS00475	ENOG4105D64	Mechanosensitive ion channel
HLB42_RS00485	ENOG4105CX6	glutaminyL-tRNA synthetase
HLB42_RS00560	ENOG4105DKQ	ROK family
HLB42_RS00570	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HLB42_RS00575	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HLB42_RS00580	ENOG4105BZU	Histidine kinase
HLB42_RS00595	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HLB42_RS00615	ENOG4105C1V	Peptidase, M16
HLB42_RS00620	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HLB42_RS00635	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HLB42_RS00640	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
HLB42_RS00645	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
HLB42_RS00650	ENOG410704R	Produces ATP from ADP in the presence of a proton gradient across the membrane
HLB42_RS00655	ENOG41089ID	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HLB42_RS00660	ENOG4106287	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HLB42_RS00665	ENOG410855G	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HLB42_RS00670	ENOG4105EBX	v-type atpase
HLB42_RS00685	ENOG4108YZA	Nitrogen regulatory protein pii
HLB42_RS00695	ENOG410868C	50s ribosomal protein l35
HLB42_RS00700	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HLB42_RS00710	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HLB42_RS00715	ENOG41080DW	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HLB42_RS00720	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HLB42_RS00725	ENOG4105DQR	SNARE associated Golgi
HLB42_RS00730	ENOG4105CSM	endonuclease III
HLB42_RS00735	ENOG4105ECY	inositol monophosphatase
HLB42_RS00750	ENOG4108Z4T	Peptidase M50
HLB42_RS00770	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HLB42_RS00780	ENOG4105WH1	Two component transcriptional regulator luxr family
HLB42_RS00800	ENOG4107V8I	Glycosyl transferases group 1
HLB42_RS00815	ENOG4108ZJ4	polysaccharide deacetylase
HLB42_RS00830	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HLB42_RS00865	ENOG4105C0B	DNA polymerase III (alpha subunit)
HLB42_RS00890	ENOG4105CH5	extracellular solute-binding protein, family 7
HLB42_RS00895	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HLB42_RS00920	ENOG4105DHP	deoxycytidine triphosphate deaminase
HLB42_RS00965	ENOG4105EEQ	Na H antiporter
HLB42_RS00970	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HLB42_RS00985	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HLB42_RS00990	ENOG4105F38	ABC transporter, permease
HLB42_RS01000	ENOG4105CHU	acetyl-coa acetyltransferase
HLB42_RS01035	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HLB42_RS01045	ENOG4105BZU	Histidine kinase
HLB42_RS01075	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HLB42_RS01080	ENOG4108VZM	50s ribosomal protein L10
HLB42_RS01085	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HLB42_RS01090	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HLB42_RS01095	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HLB42_RS01100	ENOG410683Z	Preprotein translocase SecE subunit
HLB42_RS01105	ENOG4105W0E	50S ribosomal protein L33
HLB42_RS01140	ENOG4105BZ1	(ABC) transporter
HLB42_RS01145	ENOG4105BZ1	(ABC) transporter
HLB42_RS01165	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HLB42_RS01200	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
HLB42_RS01205	ENOG4105CD3	dihydroorotase
HLB42_RS01215	ENOG4105DXM	phenylacetic acid degradation protein
HLB42_RS01235	ENOG4105C30	Nad-dependent epimerase dehydratase
HLB42_RS01240	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
HLB42_RS01260	ENOG4105CDU	Replicative dna helicase
HLB42_RS01270	ENOG4106855	Competence protein
HLB42_RS01285	ENOG4105KAF	membrAne
HLB42_RS01290	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
HLB42_RS01295	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HLB42_RS01300	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HLB42_RS01305	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HLB42_RS01325	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
HLB42_RS01340	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HLB42_RS01345	ENOG4105CXT	aspartate transcarbamylase
HLB42_RS01355	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HLB42_RS01365	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
HLB42_RS01370	ENOG4108IUZ	ABC transporter
HLB42_RS01380	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HLB42_RS01385	ENOG4105EW9	transcriptional regulator AsnC family
HLB42_RS01390	ENOG4105DCF	alanine dehydrogenase
HLB42_RS01400	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HLB42_RS01410	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HLB42_RS01440	ENOG4105E39	Enoyl-CoA hydratase
HLB42_RS01445	ENOG4108XHF	Pfam:DUF178
HLB42_RS01455	ENOG4105DVY	radical SAM domain protein
HLB42_RS01500	ENOG4107Y6J	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
HLB42_RS01555	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HLB42_RS01575	ENOG4105BZ4	penicillin-binding protein
HLB42_RS01585	ENOG4105C9B	Cysteine desulfurase
HLB42_RS01595	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
HLB42_RS01635	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HLB42_RS01650	ENOG4105BZU	Histidine kinase
HLB42_RS01660	ENOG4105D75	Capsular exopolysaccharide family
HLB42_RS01685	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HLB42_RS01690	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
HLB42_RS01695	ENOG4107R49	K07407 alpha-galactosidase EC 3.2.1.22
HLB42_RS01705	ENOG4105DRS	transport system, permease
HLB42_RS01720	ENOG4105E98	transcriptional regulator DeoR family
HLB42_RS01725	ENOG4105VZ8	Transcriptional regulator
HLB42_RS01735	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
HLB42_RS01740	ENOG4108Z03	MAF-like protein
HLB42_RS01745	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HLB42_RS01755	ENOG4105CJN	penicillin-binding protein
HLB42_RS01780	ENOG4105WH1	Two component transcriptional regulator luxr family
HLB42_RS01805	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HLB42_RS01830	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS01835	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HLB42_RS01845	ENOG4108ZAF	Molybdopterin
HLB42_RS01860	ENOG4107EUI	c reductase, iron-sulfur
HLB42_RS01875	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HLB42_RS01880	ENOG4105DA4	cytochrome c-type biogenesis protein
HLB42_RS01885	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
HLB42_RS01895	ENOG41060IM	Heme exporter protein
HLB42_RS01910	ENOG4105CG5	Glycosyl transferase (Group 1
HLB42_RS01915	ENOG4105DHF	Membrane
HLB42_RS01920	ENOG4105KJF	protein tyrosine phosphatase
HLB42_RS01930	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HLB42_RS01945	ENOG4105NAU	thioesterase Superfamily protein
HLB42_RS01955	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HLB42_RS01960	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HLB42_RS01970	ENOG4107SNB	ankyrin repeat protein YahD
HLB42_RS01975	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HLB42_RS01990	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
HLB42_RS02000	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HLB42_RS02005	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HLB42_RS02010	ENOG4106GF2	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HLB42_RS02015	ENOG4105VB6	UPF0109 protein
HLB42_RS02020	ENOG4105K5M	30s ribosomal protein S16
HLB42_RS02045	ENOG4105E2Y	ABC, transporter
HLB42_RS02050	ENOG4107Y9U	Membrane
HLB42_RS02065	ENOG4108Z5K	methylglyoxal synthase
HLB42_RS02070	ENOG4105MJ2	Competence protein
HLB42_RS02110	ENOG4105K4P	CoA-binding domain protein
HLB42_RS02115	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HLB42_RS02160	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HLB42_RS02175	ENOG41089UC	methyltransferase, type 11
HLB42_RS02190	ENOG4105MSB	protein, conserved in bacteria
HLB42_RS02215	ENOG4106G6Q	Transcriptional regulator
HLB42_RS02230	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS02235	ENOG4105D17	glycoside hydrolase, family 3 domain protein
HLB42_RS02260	ENOG4107HP6	Transcriptional regulator
HLB42_RS02270	ENOG4105DEF	Extracellular solute-binding protein, family 5
HLB42_RS02280	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS02290	ENOG4105DEF	Extracellular solute-binding protein, family 5
HLB42_RS02305	ENOG4105DC7	peptidase M24
HLB42_RS02315	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS02320	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS02325	ENOG4105DEF	Extracellular solute-binding protein, family 5
HLB42_RS02345	ENOG4105BZU	Histidine kinase
HLB42_RS02355	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HLB42_RS02370	ENOG4105C0H	protease
HLB42_RS02395	ENOG4105C0Z	ABC transporter
HLB42_RS02400	ENOG4108IV0	ABC, transporter
HLB42_RS02410	ENOG4105C32	Amino acid ABC transporter (Permease)
HLB42_RS02420	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
HLB42_RS02425	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HLB42_RS02445	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
HLB42_RS02450	ENOG4107QIV	Cytochrome c biogenesis protein
HLB42_RS02455	ENOG4105CRQ	synthase (Component I)
HLB42_RS02465	ENOG4105DDQ	anthranilate synthase
HLB42_RS02470	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HLB42_RS02475	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HLB42_RS02500	ENOG4108JPW	Aminotransferase
HLB42_RS02510	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HLB42_RS02515	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
HLB42_RS02530	ENOG4105CAT	Cytidine monophosphate kinase
HLB42_RS02550	ENOG4108QT4	peptidase S8 and S53, subtilisin, kexin, sedolisin
HLB42_RS02560	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
HLB42_RS02585	ENOG4105DEF	Extracellular solute-binding protein, family 5
HLB42_RS02595	ENOG4108HNZ	carboxyl transferase
HLB42_RS02605	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
HLB42_RS02620	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HLB42_RS02625	ENOG4107RIQ	Sulfate adenylate transferase
HLB42_RS02630	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
HLB42_RS02635	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
HLB42_RS02640	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HLB42_RS02650	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HLB42_RS02655	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HLB42_RS02660	ENOG4107T5V	SNARE associated Golgi
HLB42_RS02670	ENOG4105F6J	Alpha beta hydrolase fold
HLB42_RS02680	ENOG4105C7S	Dehydrogenase
HLB42_RS02690	ENOG4105DTQ	mandelate racemase muconate lactonizing
HLB42_RS02705	ENOG4105CTP	PilT protein domain protein
HLB42_RS02715	ENOG4108594	Permease of the drug metabolite transporter
HLB42_RS02730	ENOG4107RVV	histidinol phosphate phosphatase, hisj family
HLB42_RS02735	ENOG4105DCG	PHP domain protein
HLB42_RS02750	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HLB42_RS02755	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HLB42_RS02760	ENOG4107SID	ATP-dependent exodnase (exonuclease v)
HLB42_RS02770	ENOG4105KWI	UPF0339 protein
HLB42_RS02785	ENOG4105C1G	acyl-Coa dehydrogenase
HLB42_RS02790	ENOG4107QX3	carboxylase
HLB42_RS02795	ENOG4105C1G	acyl-Coa dehydrogenase
HLB42_RS02825	ENOG4105C01	Dihydroxy-acid dehydratase
HLB42_RS02830	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HLB42_RS02835	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HLB42_RS02840	ENOG4105BZU	Histidine kinase
HLB42_RS02845	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HLB42_RS02850	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HLB42_RS02855	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HLB42_RS02860	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HLB42_RS02865	ENOG4105GKE	subunit e
HLB42_RS02870	ENOG4107EEP	NADH dehydrogenase (quinone) (EC 1.6.99.5)
HLB42_RS02875	ENOG4108IEH	NADH dehydrogenase subunit g
HLB42_RS02880	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HLB42_RS02885	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HLB42_RS02890	ENOG4107YX3	NADH dehydrogenase subunit j
HLB42_RS02895	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HLB42_RS02900	ENOG4105D65	subunit l
HLB42_RS02905	ENOG4107WFQ	NADH-quinone oxidoreductase, chain M
HLB42_RS02910	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HLB42_RS02945	ENOG4105C98	muts2 protein
HLB42_RS02960	ENOG4105RTX	GreA GreB family elongation factor
HLB42_RS02970	ENOG4105CRK	lysyL-tRNA synthetase
HLB42_RS02985	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
HLB42_RS02990	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HLB42_RS02995	ENOG4108KXV	response regulator
HLB42_RS03000	ENOG4105BZ4	penicillin-binding protein
HLB42_RS03015	ENOG4107FW0	short-chain dehydrogenase reductase
HLB42_RS03055	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HLB42_RS03060	ENOG4105CN9	Peptidase m42 family protein
HLB42_RS03065	ENOG4107QN2	dihydrolipoyl dehydrogenase
HLB42_RS03070	ENOG4106A3M	Cytochrome p-450
HLB42_RS03085	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HLB42_RS03110	ENOG4105BZU	Histidine kinase
HLB42_RS03135	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HLB42_RS03145	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HLB42_RS03155	ENOG4105E5Q	amino acid AbC transporter
HLB42_RS03160	ENOG4105EAB	amino acid AbC transporter
HLB42_RS03170	ENOG4105EAB	amino acid AbC transporter
HLB42_RS03175	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HLB42_RS03180	ENOG4105CP9	extracellular ligand-binding receptor
HLB42_RS03195	ENOG4105KHC	sulfurtransferase
HLB42_RS03205	ENOG4105CSA	Coproporphyrinogen iii oxidase
HLB42_RS03220	ENOG4105C0D	helicase
HLB42_RS03250	ENOG4105DJ2	Major Facilitator Superfamily
HLB42_RS03260	ENOG4105CPD	ethanolamine ammonia-lyase
HLB42_RS03265	ENOG4107FQ9	ethanolamine ammonia-lyase
HLB42_RS03280	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HLB42_RS03290	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HLB42_RS03295	ENOG4107RCV	ABC transporter, permease
HLB42_RS03300	ENOG4105C4Y	ABC transporter
HLB42_RS03310	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
HLB42_RS03315	ENOG4108MRH	transcriptional regulatory protein
HLB42_RS03325	ENOG4105C7W	Xanthine dehydrogenase
HLB42_RS03330	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
HLB42_RS03335	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
HLB42_RS03345	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HLB42_RS03355	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HLB42_RS03370	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HLB42_RS03375	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HLB42_RS03390	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HLB42_RS03395	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HLB42_RS03400	ENOG4105CHW	UPF0052 protein
HLB42_RS03405	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HLB42_RS03415	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HLB42_RS03420	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HLB42_RS03455	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
HLB42_RS03465	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HLB42_RS03470	ENOG4108SGK	Tetr family transcriptional regulator
HLB42_RS03475	ENOG4105MS2	ribosomal subunit Interface protein
HLB42_RS03480	ENOG4105CKM	Branched-chain carboxylic acid kinase
HLB42_RS03490	ENOG4108ZBR	Gcn5-related n-acetyltransferase
HLB42_RS03500	ENOG4107R13	MMPL domain protein
HLB42_RS03505	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HLB42_RS03515	ENOG410667J	hydrolase
HLB42_RS03520	ENOG4107ZY0	Phenazine biosynthesis-like protein
HLB42_RS03535	ENOG4105CDA	abc transporter atp-binding protein
HLB42_RS03540	ENOG4105H1G	trap transporter solute receptor taxi family
HLB42_RS03570	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HLB42_RS03580	ENOG4105E5J	UV damage endonuclease
HLB42_RS03605	ENOG4105CXV	gliding motility protein
HLB42_RS03610	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HLB42_RS03615	ENOG4105D65	subunit l
HLB42_RS03620	ENOG4105HC0	Na H antiporter
HLB42_RS03625	ENOG4108ZE9	Monovalent cation H antiporter subunit C
HLB42_RS03630	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HLB42_RS03645	ENOG4105KJM	monovalent cation h antiporter subunit g
HLB42_RS03650	ENOG4105KG3	cytidine deaminase
HLB42_RS03655	ENOG4105C37	(CBS) domain
HLB42_RS03660	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
HLB42_RS03665	ENOG4105J8Z	peptidase S8 and S53, subtilisin, kexin, sedolisin
HLB42_RS03680	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HLB42_RS03685	ENOG4108YYS	metal-dependent hydrolase (By similarity)
HLB42_RS03690	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
HLB42_RS03700	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HLB42_RS03705	ENOG4105D8X	mechanosensitive ion channel
HLB42_RS03725	ENOG4105C75	arginyL-tRNA synthetase
HLB42_RS03745	ENOG4105DA5	(ABC) transporter
HLB42_RS03765	ENOG4105DSE	periplasmic solute binding protein
HLB42_RS03790	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HLB42_RS03815	ENOG4105CY0	Metallo-Beta-Lactamase
HLB42_RS03825	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
HLB42_RS03830	ENOG4105EHG	Permease protein
HLB42_RS03835	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HLB42_RS03850	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HLB42_RS03865	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HLB42_RS03870	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HLB42_RS03880	ENOG4105NAA	Cytochrome C oxidase, subunit II
HLB42_RS03885	ENOG4107RQ2	Cytochrome c oxidase, subunit I
HLB42_RS03895	ENOG4107RST	alpha/beta hydrolase fold
HLB42_RS03900	ENOG4108IQK	o-acetylhomoserine
HLB42_RS03915	ENOG4105I3K	Ferric uptake regulator, Fur family
HLB42_RS03935	ENOG4105FE1	phytoene synthase
HLB42_RS03940	ENOG4105CGH	5'-nucleotidase
HLB42_RS03950	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HLB42_RS03955	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
HLB42_RS03960	ENOG4107T8J	thymidine kinase
HLB42_RS03965	ENOG41082HT	Binds the 23S rRNA (By similarity)
HLB42_RS03970	ENOG4105CZN	Potassium uptake protein
HLB42_RS04000	ENOG4105VT2	5-hydroxyisourate hydrolase
HLB42_RS04015	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HLB42_RS04025	ENOG4105EBR	Carboxylesterase
HLB42_RS04030	ENOG4107TYG	Oxidoreductase domain-containing protein
HLB42_RS04040	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HLB42_RS04050	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HLB42_RS04075	ENOG4105K70	DNA-binding protein
HLB42_RS04080	ENOG4105D06	uba thif-type nad fad binding protein
HLB42_RS04085	ENOG41071YG	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HLB42_RS04095	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HLB42_RS04115	ENOG4107U4Q	acetylglutamate kinase
HLB42_RS04120	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HLB42_RS04130	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HLB42_RS04140	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
HLB42_RS04145	ENOG4105CPF	Cell wall formation (By similarity)
HLB42_RS04150	ENOG4105EB3	Histidine kinase
HLB42_RS04155	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HLB42_RS04175	ENOG4105C19	ABC transporter
HLB42_RS04180	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HLB42_RS04215	ENOG4105C12	Phosphoribosylglycinamide synthetase
HLB42_RS04220	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
HLB42_RS04260	ENOG41080QG	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HLB42_RS04275	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HLB42_RS04280	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HLB42_RS04285	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
HLB42_RS04290	ENOG4107QWW	Cell wall formation (By similarity)
HLB42_RS04295	ENOG4105DFU	Cell wall formation (By similarity)
HLB42_RS04300	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HLB42_RS04310	ENOG4105ESP	cell wall surface anchor family protein
HLB42_RS04320	ENOG4108S01	response regulator
HLB42_RS04330	ENOG4105C5X	domain protein
HLB42_RS04350	ENOG4105E9Z	Nad-dependent epimerase dehydratase
HLB42_RS04355	ENOG4105CPC	Aldo Keto reductase
HLB42_RS04375	ENOG4108TVJ	Nitroreductase
HLB42_RS04395	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HLB42_RS04415	ENOG41080HT	Transcriptional regulator, arsr family
HLB42_RS04420	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HLB42_RS04435	ENOG4105C10	Electron transfer flavoprotein
HLB42_RS04440	ENOG4105TPV	
HLB42_RS04465	ENOG4107QW3	Sucrose phosphorylase
HLB42_RS04515	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HLB42_RS04525	ENOG4105DEF	Extracellular solute-binding protein, family 5
HLB42_RS04530	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS04535	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS04545	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HLB42_RS04555	ENOG4105KA0	thioesterase Superfamily protein
HLB42_RS04585	ENOG4105BZU	Histidine kinase
HLB42_RS04600	ENOG4105CJ1	ABC, transporter
HLB42_RS04625	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HLB42_RS04630	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HLB42_RS04650	ENOG4105VMP	Transcriptional regulator
HLB42_RS04655	ENOG410667J	hydrolase
HLB42_RS04695	ENOG4105DIH	basic membrane
HLB42_RS04700	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HLB42_RS04710	ENOG410803B	Involved in the transcription termination process (By similarity)
HLB42_RS04715	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HLB42_RS04730	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HLB42_RS04735	ENOG4105C5F	glutamine synthetase
HLB42_RS04745	ENOG4105C32	Amino acid ABC transporter (Permease)
HLB42_RS04750	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HLB42_RS04755	ENOG4105C0Z	ABC transporter
HLB42_RS04760	ENOG4108IV0	ABC, transporter
HLB42_RS04780	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
HLB42_RS04785	ENOG4107ZZY	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HLB42_RS04805	ENOG4105DEN	Luciferase family
HLB42_RS04810	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HLB42_RS04815	ENOG4105CQB	FAD linked oxidase domain protein
HLB42_RS04825	ENOG4105DMF	Dehydrogenase
HLB42_RS04830	ENOG4105CGH	5'-nucleotidase
HLB42_RS04840	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
HLB42_RS04870	ENOG4105C1G	acyl-Coa dehydrogenase
HLB42_RS04880	ENOG4105D9P	serine threonine protein kinase
HLB42_RS04885	ENOG4107YBY	Hydrolase
HLB42_RS04890	ENOG4105CAY	ferredoxin--nadp reductase
HLB42_RS04895	ENOG4105EQH	reductase
HLB42_RS04905	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
HLB42_RS04910	ENOG4107YU2	histidine triad (hIT) protein
HLB42_RS04925	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HLB42_RS04935	ENOG41067SE	Tetr family transcriptional regulator
HLB42_RS04940	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HLB42_RS04950	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HLB42_RS04960	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
HLB42_RS04980	ENOG4105DTQ	mandelate racemase muconate lactonizing
HLB42_RS04990	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS04995	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS05000	ENOG4105HJK	ABC transporter
HLB42_RS05015	ENOG4106G6Q	Transcriptional regulator
HLB42_RS05020	ENOG4108J2R	molybdopterin oxidoreductase
HLB42_RS05055	ENOG4105XT2	Transcriptional regulator
HLB42_RS05065	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HLB42_RS05070	ENOG4105NWN	ApaG protein
HLB42_RS05090	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HLB42_RS05095	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HLB42_RS05110	ENOG4107TT5	NLP P60 protein
HLB42_RS05130	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HLB42_RS05135	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HLB42_RS05145	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HLB42_RS05150	ENOG4105ESV	Glycosyl transferase, family 4
HLB42_RS05170	ENOG4105CHU	acetyl-coa acetyltransferase
HLB42_RS05200	ENOG4108UNV	SUF system FeS assembly protein, NifU family
HLB42_RS05205	ENOG4105C9B	Cysteine desulfurase
HLB42_RS05210	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
HLB42_RS05215	ENOG4106TNF	Periplasmic binding protein
HLB42_RS05220	ENOG4105F22	Major Facilitator Superfamily
HLB42_RS05235	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HLB42_RS05240	ENOG4107STF	Involved in phosphonate degradation (By similarity)
HLB42_RS05250	ENOG4105F95	Monooxygenase
HLB42_RS05260	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HLB42_RS05275	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HLB42_RS05295	ENOG4108SA1	esterase
HLB42_RS05300	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HLB42_RS05310	ENOG4105EAB	amino acid AbC transporter
HLB42_RS05315	ENOG4105D49	3-dehydroquinate synthase
HLB42_RS05320	ENOG4107ZC0	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HLB42_RS05325	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HLB42_RS05375	ENOG4105DP4	dak2 domain fusion protein ylov
HLB42_RS05385	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HLB42_RS05395	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HLB42_RS05405	ENOG4105MXW	flavin reductase domain protein, FMN-binding
HLB42_RS05410	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HLB42_RS05415	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HLB42_RS05420	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HLB42_RS05435	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HLB42_RS05440	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HLB42_RS05445	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HLB42_RS05450	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HLB42_RS05455	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HLB42_RS05460	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HLB42_RS05465	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HLB42_RS05470	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HLB42_RS05475	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HLB42_RS05480	ENOG4108CHD	50s ribosomal protein l29
HLB42_RS05485	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HLB42_RS05490	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HLB42_RS05495	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HLB42_RS05500	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HLB42_RS05505	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HLB42_RS05510	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HLB42_RS05515	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HLB42_RS05520	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HLB42_RS05525	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HLB42_RS05530	ENOG410856V	50S ribosomal protein L30
HLB42_RS05535	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HLB42_RS05540	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HLB42_RS05545	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HLB42_RS05565	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
HLB42_RS05580	ENOG4105DEG	Vwa containing coxe family protein
HLB42_RS05585	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HLB42_RS05595	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HLB42_RS05600	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HLB42_RS05605	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HLB42_RS05610	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HLB42_RS05615	ENOG4108ZT0	50S ribosomal protein l17
HLB42_RS05620	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
HLB42_RS05635	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HLB42_RS05640	ENOG4105F8D	glycoside hydrolase family 4
HLB42_RS05645	ENOG4108JQ7	(ABC) transporter
HLB42_RS05665	ENOG4105ETE	Transcriptional regulator (LacI family
HLB42_RS05680	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HLB42_RS05700	ENOG41086Q6	ribosome-binding factor A
HLB42_RS05705	ENOG41068JE	domain protein
HLB42_RS05725	ENOG4105MA4	psp1 domain protein
HLB42_RS05730	ENOG4105KME	endoribonuclease L-psp
HLB42_RS05735	ENOG4108ZF3	Phosphatase
HLB42_RS05740	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HLB42_RS05745	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HLB42_RS05755	ENOG4105FE9	pseudouridine synthase
HLB42_RS05760	ENOG4105EJQ	L-serine dehydratase
HLB42_RS05775	ENOG4108W63	CRP FNR family transcriptional regulator
HLB42_RS05780	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HLB42_RS05810	ENOG4105K63	Thioredoxin
HLB42_RS05825	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HLB42_RS05850	ENOG4108IXY	short-chain dehydrogenase reductase
HLB42_RS05855	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HLB42_RS05870	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HLB42_RS05875	ENOG4108784	2'-5' rna ligase
HLB42_RS05880	ENOG4105CEV	competence damage-inducible protein
HLB42_RS05900	ENOG4105BZU	Histidine kinase
HLB42_RS05905	ENOG4105WH1	Two component transcriptional regulator luxr family
HLB42_RS05915	ENOG410681U	heavy metal transport detoxification protein
HLB42_RS05925	ENOG4105C5H	ABC transporter
HLB42_RS05960	ENOG41061CK	Antibiotic biosynthesis monooxygenase
HLB42_RS05970	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HLB42_RS05975	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HLB42_RS05980	ENOG4105CMR	udp-glucose 4-epimerase
HLB42_RS05985	ENOG41068JE	domain protein
HLB42_RS05995	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
HLB42_RS06005	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HLB42_RS06010	ENOG4105C6E	dna polymerase iii
HLB42_RS06045	ENOG4108ZGY	Transcriptional regulator (AsnC family)
HLB42_RS06055	ENOG4105CKI	cobalamin synthesis protein
HLB42_RS06065	ENOG4105KA0	thioesterase Superfamily protein
HLB42_RS06070	ENOG4105D82	Glutamate dehydrogenase
HLB42_RS06110	ENOG4105EAH	synthase
HLB42_RS06115	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
HLB42_RS06125	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
HLB42_RS06130	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
HLB42_RS06135	ENOG4106YGA	NADH dehydrogenase (quinone)
HLB42_RS06145	ENOG4107R28	alpha amylase, catalytic region
HLB42_RS06165	ENOG4105C32	Amino acid ABC transporter (Permease)
HLB42_RS06175	ENOG4105C0Z	ABC transporter
HLB42_RS06180	ENOG4108IV0	ABC, transporter
HLB42_RS06185	ENOG4108W8B	Beta-lactamase domain protein
HLB42_RS06190	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HLB42_RS06220	ENOG4107QM2	Aldo Keto reductase
HLB42_RS06245	ENOG4105C8T	Leucyl-tRNA synthetase
HLB42_RS06270	ENOG4105C5R	Aminotransferase
HLB42_RS06275	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HLB42_RS06295	ENOG4107XM9	(LipO)protein
HLB42_RS06310	ENOG4105C2M	dna polymerase I
HLB42_RS06315	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
HLB42_RS06325	ENOG4105X0R	protein from nitrogen regulatory protein P-II
HLB42_RS06330	ENOG4105C4R	Atp-dependent dna helicase
HLB42_RS06335	ENOG4105CPC	Aldo Keto reductase
HLB42_RS06375	ENOG4105E09	nadh pyrophosphatase
HLB42_RS06390	ENOG4105DF6	Fe-S oxidoreductase
HLB42_RS06395	ENOG4105EPR	degv family
HLB42_RS06405	ENOG4105VIZ	double-strand break repair protein
HLB42_RS06410	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HLB42_RS06415	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HLB42_RS06420	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HLB42_RS06440	ENOG4107R0W	ABC transporter
HLB42_RS06510	ENOG4108IAJ	Nad-dependent epimerase dehydratase
HLB42_RS06525	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HLB42_RS06530	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HLB42_RS06535	ENOG4105DKB	L-sorbosone dehydrogenase
HLB42_RS06565	ENOG4105EHM	Aminoglycoside phosphotransferase
HLB42_RS06575	ENOG4105CIY	formyltetrahydrofolate deformylase
HLB42_RS06590	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
HLB42_RS06605	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
HLB42_RS06610	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HLB42_RS06630	ENOG4105D52	delta-aminolevulinic acid dehydratase
HLB42_RS06655	ENOG4105E33	succinate dehydrogenase
HLB42_RS06660	ENOG4108J01	L-aspartate oxidase
HLB42_RS06765	ENOG4108UCS	ABC, transporter
HLB42_RS06780	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
HLB42_RS06795	ENOG4107RE3	peptidase, S41
HLB42_RS06810	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
HLB42_RS06815	ENOG4105DRS	transport system, permease
HLB42_RS06820	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
HLB42_RS06835	ENOG4106IQC	argininosuccinate lyase
HLB42_RS06845	ENOG4105BZU	Histidine kinase
HLB42_RS06850	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HLB42_RS06860	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HLB42_RS06870	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HLB42_RS06875	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
HLB42_RS06880	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HLB42_RS06885	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HLB42_RS06890	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HLB42_RS06905	ENOG4105CHU	acetyl-coa acetyltransferase
HLB42_RS06910	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
HLB42_RS06915	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
HLB42_RS06925	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
HLB42_RS06930	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HLB42_RS06940	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HLB42_RS06955	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HLB42_RS06965	ENOG4105C7K	acetolactate synthase
HLB42_RS06975	ENOG4105C1J	atp-dependent rna helicase
HLB42_RS06985	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HLB42_RS07005	ENOG4105C3M	thioredoxin reductase
HLB42_RS07015	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HLB42_RS07020	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HLB42_RS07025	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HLB42_RS07035	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
HLB42_RS07050	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HLB42_RS07080	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HLB42_RS07100	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HLB42_RS07105	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HLB42_RS07110	ENOG4105CV8	reductase
HLB42_RS07140	ENOG4106RE7	Cytochrome
HLB42_RS07150	ENOG4108JQ9	ABC transporter
HLB42_RS07155	ENOG4105C87	Aminotransferase class I and II
HLB42_RS07160	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HLB42_RS07205	ENOG4105CGP	Urocanate hydratase
HLB42_RS07215	ENOG4105CI2	imidazolone-5-propionate hydrolase
HLB42_RS07220	ENOG4105C84	Histidine ammonia-lyase
HLB42_RS07225	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HLB42_RS07240	ENOG4105CJ1	ABC, transporter
HLB42_RS07245	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HLB42_RS07250	ENOG4105DKB	L-sorbosone dehydrogenase
HLB42_RS07255	ENOG4105E63	Pfam:DUF178
HLB42_RS07265	ENOG4105DTN	riboflavin biosynthesis protein ribF
HLB42_RS07275	ENOG4108Z6B	deaminase
HLB42_RS07280	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HLB42_RS07285	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HLB42_RS07290	ENOG4105D48	metallophosphoesterase
HLB42_RS07305	ENOG4105FQP	Beta-lactamase
HLB42_RS07315	ENOG4105CHU	acetyl-coa acetyltransferase
HLB42_RS07330	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HLB42_RS07350	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS07355	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS07360	ENOG4105DEF	Extracellular solute-binding protein, family 5
HLB42_RS07370	ENOG4105BZ7	extracellular solute-binding protein family 1
HLB42_RS07375	ENOG4105D17	glycoside hydrolase, family 3 domain protein
HLB42_RS07380	ENOG4105EPR	degv family
HLB42_RS07395	ENOG4108Z7F	N-acetyltransferase
HLB42_RS07405	ENOG4105CE9	30S ribosomal protein S2
HLB42_RS07410	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HLB42_RS07415	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HLB42_RS07420	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HLB42_RS07425	ENOG4105KNE	Phosphatidate cytidylyltransferase
HLB42_RS07450	ENOG4105C3G	gtp-binding protein
HLB42_RS07455	ENOG4105BZU	Histidine kinase
HLB42_RS07475	ENOG4108J5G	6-phosphogluconate dehydrogenase
HLB42_RS07480	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
HLB42_RS07500	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HLB42_RS07505	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HLB42_RS07520	ENOG4105KVY	Required for disulfide bond formation in some proteins (By similarity)
HLB42_RS07545	ENOG4105EGE	secreted protein
HLB42_RS07550	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HLB42_RS07555	ENOG4108JFJ	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HLB42_RS07560	ENOG4105K5B	UPF0225 protein
HLB42_RS07565	ENOG4108RWN	rrna methyltransferase
HLB42_RS07580	ENOG4105C8F	Beta-lactamase domain protein
HLB42_RS07585	ENOG4107QI1	Mate efflux family protein
HLB42_RS07590	ENOG4105CS1	NAD(P)H quinone oxidoreductase
HLB42_RS07600	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HLB42_RS07605	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HLB42_RS07620	ENOG4107SJW	iron permease, FTR1
HLB42_RS07635	ENOG4105CBT	Fructose-1,6-bisphosphatase
HLB42_RS07755	ENOG4105C0D	helicase
HLB42_RS07895	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HLB42_RS07940	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HLB42_RS07950	ENOG4108IEG	Formate dehydrogenase Alpha subunit
HLB42_RS07975	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HLB42_RS07980	ENOG4105DXN	mazG family
HLB42_RS07995	ENOG4108RZ4	Short-chain dehydrogenase reductase Sdr
HLB42_RS08005	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HLB42_RS08010	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HLB42_RS08050	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HLB42_RS08055	ENOG4105CQ7	ATP-dependent helicase
HLB42_RS08060	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HLB42_RS08070	ENOG4107TE5	Lipid kinase
HLB42_RS08080	ENOG4105C5S	asparaginyl-tRNA synthetase
HLB42_RS08085	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HLB42_RS08090	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HLB42_RS08095	ENOG4105EEQ	Na H antiporter
HLB42_RS08100	ENOG4107S2Z	UPF0761 membrane protein
HLB42_RS08105	ENOG4105KIP	Thioesterase
HLB42_RS08110	ENOG4107R1I	NAD-dependent malic enzyme
HLB42_RS08120	ENOG4105CHU	acetyl-coa acetyltransferase
HLB42_RS08125	ENOG4108IIH	CoA-transferase subunit B
HLB42_RS08135	ENOG4105K6T	rare lipoprotein A
HLB42_RS08140	ENOG4105DC7	peptidase M24
HLB42_RS08145	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HLB42_RS08150	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HLB42_RS08170	ENOG4105C9M	aspartyl-trna synthetase
HLB42_RS08175	ENOG4105CUT	histidyl-tRNA synthetase
HLB42_RS08195	ENOG4108J6E	Pfam:Phage_integr_N
HLB42_RS08200	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HLB42_RS08210	ENOG4105C5R	Aminotransferase
HLB42_RS08220	ENOG4108IGT	Dipeptidase
HLB42_RS08225	ENOG4107SN7	NLP P60 protein
HLB42_RS08230	ENOG4107STG	mandelate racemase muconate lactonizing
HLB42_RS08240	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
HLB42_RS08245	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
HLB42_RS08250	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HLB42_RS08255	ENOG4105DR5	peptidase
HLB42_RS08260	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HLB42_RS08270	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HLB42_RS08280	ENOG4105CPK	Glycosyl transferase (Group 1
HLB42_RS08285	ENOG4105GCF	PGAM
HLB42_RS08295	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HLB42_RS08300	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HLB42_RS08315	ENOG4105ETE	Transcriptional regulator (LacI family
HLB42_RS08330	ENOG4105DRS	transport system, permease
HLB42_RS08345	ENOG4105DSG	hydrolase family 43
HLB42_RS08360	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HLB42_RS08365	ENOG4105BZA	Phosphoglycerate kinase
HLB42_RS08370	ENOG4105CP7	Triose-phosphate isomerase
HLB42_RS08375	ENOG4107FKK	extracellular solute-binding protein family 1
HLB42_RS08380	ENOG4105DPN	Oligoendopeptidase f
HLB42_RS08385	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HLB42_RS08400	ENOG4108S93	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HLB42_RS08410	ENOG4105C59	p-type ATPase
HLB42_RS08445	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HLB42_RS08450	ENOG4108UVJ	appr-1-p processing domain protein
HLB42_RS08460	ENOG41087YS	Phage shock protein A
HLB42_RS08475	ENOG4105D9P	serine threonine protein kinase
HLB42_RS08480	ENOG4107QI6	Cysteine desulfurase
HLB42_RS08505	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HLB42_RS08515	ENOG4105IJD	ferritin dps family protein
HLB42_RS08530	ENOG4105CPC	Aldo Keto reductase
HLB42_RS08555	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
HLB42_RS08575	ENOG4105C0H	protease
HLB42_RS08580	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HLB42_RS08585	ENOG4105CQC	Prephenate dehydratase
HLB42_RS08590	ENOG4105PDP	Short chain dehydrogenase
HLB42_RS08610	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HLB42_RS08635	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HLB42_RS08640	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HLB42_RS08655	ENOG41074B2	UPF0747 protein
HLB42_RS08660	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HLB42_RS08665	ENOG4105ENE	Histidine kinase
HLB42_RS08675	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HLB42_RS08680	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HLB42_RS08685	ENOG4105CRQ	synthase (Component I)
HLB42_RS08700	ENOG4105CE1	Ferrous iron transport protein b
HLB42_RS08710	ENOG4105C34	Pseudouridine synthase
HLB42_RS08715	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HLB42_RS08725	ENOG4108M3P	Membrane
HLB42_RS08730	ENOG4107Y3Y	amidohydrolase
HLB42_RS08740	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HLB42_RS08745	ENOG4105DJV	ribulose-phosphate 3-epimerase
HLB42_RS08750	ENOG4108N5B	2-phosphosulfolactate phosphatase
HLB42_RS08800	ENOG4106A3M	Cytochrome p-450
HLB42_RS08810	ENOG4105DFA	alanine racemase domain protein
HLB42_RS08825	ENOG4105BZ1	(ABC) transporter
HLB42_RS08830	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
HLB42_RS08845	ENOG4105C7B	Threonine dehydratase
HLB42_RS08850	ENOG4105C72	UPF0176 protein
HLB42_RS08880	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HLB42_RS08890	ENOG4105VTR	Integrase
HLB42_RS08950	ENOG4105C4R	Atp-dependent dna helicase
HLB42_RS08960	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HLB42_RS08975	ENOG4108I5C	dEAD DEAH box helicase
HLB42_RS08980	ENOG4105C0D	helicase
HLB42_RS09015	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
HLB42_RS09015	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
HLB42_RS09025	ENOG4105DWV	Homoserine O-trans-acetylase
HLB42_RS09035	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HLB42_RS09040	ENOG4105C32	Amino acid ABC transporter (Permease)
HLB42_RS09050	ENOG4105C0Z	ABC transporter
HLB42_RS09055	ENOG4108IV0	ABC, transporter
HLB42_RS09065	ENOG4105DTD	Dehydrogenase
HLB42_RS09075	ENOG4105DGW	oligopeptidase A
HLB42_RS09080	ENOG4107S91	Sodium hydrogen exchanger
HLB42_RS09090	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HLB42_RS09110	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HLB42_RS09120	ENOG4105CJR	Integral membrane protein (MviN
HLB42_RS09145	ENOG4105EEM	helicase
HLB42_RS09150	ENOG4106M28	alanine racemase domain protein
HLB42_RS09170	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
HLB42_RS09180	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
HLB42_RS09190	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HLB42_RS09205	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HLB42_RS09215	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
HLB42_RS09220	ENOG4105EG2	ABC transporter, permease
HLB42_RS09225	ENOG4105D56	permease protein
HLB42_RS09270	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HLB42_RS09275	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HLB42_RS09280	ENOG4107T3P	ABC, transporter
HLB42_RS09305	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HLB42_RS09315	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HLB42_RS09335	ENOG4105DZS	Phenylacetate-CoA ligase
HLB42_RS09340	ENOG4108IV0	ABC, transporter
HLB42_RS09350	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HLB42_RS09360	ENOG4108IQE	Amp-dependent synthetase and ligase
HLB42_RS09365	ENOG4105C0Z	ABC transporter
HLB42_RS09370	ENOG4105CEY	Amp-dependent synthetase and ligase
HLB42_RS09390	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HLB42_RS09395	ENOG4108UJU	UPF0301 protein
HLB42_RS09400	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HLB42_RS09415	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HLB42_RS09420	ENOG4105E4C	Lytic transglycosylase catalytic
HLB42_RS09445	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HLB42_RS09450	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HLB42_RS09490	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
HLB42_RS09830	ENOG4105BZU	Histidine kinase
HLB42_RS09840	ENOG4105KCT	ABC transporter
HLB42_RS09845	ENOG4108M15	ABC transporter
HLB42_RS09855	ENOG4108Z4U	Ferredoxin
HLB42_RS09870	ENOG4107R1M	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity)
HLB42_RS09875	ENOG4108VX5	3-methyladenine DNA glycosylase
HLB42_RS09880	ENOG4105C94	Transporter
HLB42_RS09895	ENOG4108IUW	ABC transporter
HLB42_RS09930	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
HLB42_RS09955	ENOG4105C1G	acyl-Coa dehydrogenase
HLB42_RS09965	ENOG4105E5Q	amino acid AbC transporter
HLB42_RS09970	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HLB42_RS09980	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
HLB42_RS09990	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HLB42_RS09995	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HLB42_RS10025	ENOG4105CJ1	ABC, transporter
HLB42_RS10030	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HLB42_RS10045	ENOG4108KGH	TRANSCRIPTIONal
HLB42_RS10055	ENOG4105CG3	alpha amylase, catalytic region
HLB42_RS10060	ENOG4105D9P	serine threonine protein kinase
HLB42_RS10080	ENOG4105C3R	Methionine synthase
HLB42_RS10090	ENOG4105CH6	catalase
HLB42_RS10095	ENOG4105G5W	regulator Fur family
HLB42_RS10115	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS10125	ENOG4107QRA	Extracellular solute-binding protein, family 5
HLB42_RS10145	ENOG4105PNM	synthesis protein
HLB42_RS10190	ENOG4105CIG	ABC transporter
HLB42_RS10205	ENOG4105CZX	twitching motility protein
HLB42_RS10210	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HLB42_RS10225	ENOG4105C83	adenylosuccinate lyase
HLB42_RS10245	ENOG4108RVA	ribokinase
HLB42_RS10255	ENOG4105CEY	Amp-dependent synthetase and ligase
HLB42_RS10260	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HLB42_RS10265	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HLB42_RS10270	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HLB42_RS10275	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HLB42_RS10285	ENOG4105C28	cystathionine
HLB42_RS10290	ENOG4107ZQV	short-chain dehydrogenase reductase
HLB42_RS10295	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HLB42_RS10300	ENOG4105DZP	Membrane-associated zinc metalloprotease
HLB42_RS10320	ENOG4108SDH	ABC, transporter
HLB42_RS10350	ENOG4105CSM	endonuclease III
HLB42_RS10375	ENOG4105C5H	ABC transporter
HLB42_RS10405	ENOG41067VY	50S ribosomal protein L32
HLB42_RS10435	ENOG4105KXX	peptidase s58 dmpa
HLB42_RS10440	ENOG4105DPN	Oligoendopeptidase f
HLB42_RS10470	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HLB42_RS10480	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HLB42_RS10485	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
HLB42_RS10490	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HLB42_RS10495	ENOG4108UJD	30S ribosomal protein S9
HLB42_RS10505	ENOG4107QX8	SPFH domain, Band 7 family protein
HLB42_RS10510	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HLB42_RS10530	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
HLB42_RS10535	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HLB42_RS10540	ENOG4105C5S	asparaginyl-tRNA synthetase
HLB42_RS10545	ENOG4105JXB	ankyrin repeat-containing protein
HLB42_RS10555	ENOG4105CFP	Peptidase U32
HLB42_RS10575	ENOG4105DJG	MaoC domain protein dehydratase
HLB42_RS10580	ENOG4105CI0	Citrate lyase
HLB42_RS10590	ENOG4105CJ1	ABC, transporter
HLB42_RS10595	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
HLB42_RS10600	ENOG410836C	Required for maturation of 30S ribosomal subunits (By similarity)
HLB42_RS10605	ENOG4105CHV	Transcription elongation factor NusA
HLB42_RS10615	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HLB42_RS10625	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HLB42_RS10630	ENOG4105CPC	Aldo Keto reductase
HLB42_RS10640	ENOG4105CN1	protease
HLB42_RS10655	ENOG4108Q5F	Tetr family transcriptional regulator
HLB42_RS10660	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HLB42_RS10675	ENOG4105D82	Glutamate dehydrogenase
HLB42_RS10680	ENOG4105D82	Glutamate dehydrogenase
HLB42_RS10685	ENOG4105EAH	synthase
HLB42_RS10720	ENOG4108159	Pfam:UPF0005
HLB42_RS10745	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
HLB42_RS10750	ENOG4105BZU	Histidine kinase
HLB42_RS10760	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HLB42_RS10765	ENOG4105II7	pyrroline-5-carboxylate reductase
HLB42_RS10775	ENOG4107QV3	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HLB42_RS10785	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
HLB42_RS10790	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
HLB42_RS10795	ENOG4105VAW	lrga family
HLB42_RS10800	ENOG41067MG	lrgb family
HLB42_RS10840	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HLB42_RS10845	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
HLB42_RS10870	ENOG4105BZ4	penicillin-binding protein
HLB42_RS10875	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
HLB42_RS10900	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HLB42_RS10905	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HLB42_RS10910	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HLB42_RS10940	ENOG4105DR5	peptidase
HLB42_RS10950	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HLB42_RS10960	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HLB42_RS10975	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HLB42_RS10990	ENOG41073R8	VanW family
HLB42_RS10995	ENOG4105C8Y	Acetylornithine aminotransferase
HLB42_RS11015	ENOG4108WBT	adenosyltransferase
HLB42_RS11020	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HLB42_RS11030	ENOG4105DAP	Nicotinate phosphoribosyltransferase
HLB42_RS11035	ENOG4105C4K	Nad synthetase
HLB42_RS11055	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
HLB42_RS11065	ENOG4105C59	p-type ATPase
HLB42_RS11085	ENOG41065KQ	synthase
HLB42_RS11090	ENOG4107S5I	aldo keto reductase
HLB42_RS11095	ENOG4108TVJ	Nitroreductase
HLB42_RS11115	ENOG4108NA0	Uncharacterized conserved protein (COG2071)
HLB42_RS11125	ENOG4106A3M	Cytochrome p-450
HLB42_RS11130	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
HLB42_RS11145	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
HLB42_RS11160	ENOG4105DIN	metallophosphoesterase
HLB42_RS11165	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HLB42_RS11170	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HLB42_RS11180	ENOG4105VF7	tolerance protein
HLB42_RS11190	ENOG4108KHX	Diguanylate cyclase
HLB42_RS11225	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HLB42_RS11240	ENOG4105DR4	Methyltransferase
HLB42_RS11245	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HLB42_RS11260	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HLB42_RS11280	ENOG4105CTQ	phosphohexokinase
HLB42_RS11285	ENOG4105CP9	extracellular ligand-binding receptor
HLB42_RS11300	ENOG4105KT7	mgtC SapB transporter
HLB42_RS11310	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HLB42_RS11325	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HLB42_RS11335	ENOG4108HMX	isocitrate dehydrogenase (NADP)
HLB42_RS11350	ENOG4105DRS	transport system, permease
HLB42_RS11380	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HLB42_RS11385	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HLB42_RS11400	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HLB42_RS11405	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HLB42_RS11430	ENOG4108Z0R	Transferase
HLB42_RS11440	ENOG4105C26	Dehydrogenase
HLB42_RS11465	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HLB42_RS11470	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HLB42_RS11475	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HLB42_RS11480	ENOG4105NAE	bifunctional deaminase-reductase domain protein
HLB42_RS11495	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HLB42_RS11510	ENOG4105C26	Dehydrogenase
HLB42_RS11520	ENOG41062BK	proline dehydrogenase
HLB42_RS11535	ENOG4105CKW	Inner membrane protein yedI
HLB42_RS11545	ENOG4108Z9K	Osmotically inducible protein
HLB42_RS11570	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HLB42_RS11585	ENOG410620I	Diguanylate cyclase
HLB42_RS11590	ENOG4105BZU	Histidine kinase
HLB42_RS11605	ENOG4105BZ1	(ABC) transporter
HLB42_RS11625	ENOG4105CSA	Coproporphyrinogen iii oxidase
HLB42_RS11650	ENOG4107RB3	L-asparaginase
HLB42_RS11655	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HLB42_RS11660	ENOG4105EUJ	GTP cyclohydrolase i
HLB42_RS11670	ENOG4105C22	threonyL-tRNA synthetase
HLB42_RS11675	ENOG4105F8V	Hydrolase, tatD family
HLB42_RS11695	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HLB42_RS11730	ENOG4105DJT	lAO AO transport system ATPase
HLB42_RS11735	ENOG4105CVJ	phosphoglycerate mutase
HLB42_RS11750	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HLB42_RS11760	ENOG4108Z9B	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HLB42_RS11770	ENOG4105CKK	Glycosyl transferase, family 2
HLB42_RS11780	ENOG4105DIN	metallophosphoesterase
HLB42_RS11800	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HLB42_RS11825	ENOG4105CGZ	zinc metallopeptidase
HLB42_RS11830	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HLB42_RS11845	ENOG4107QKW	extracellular solute-binding protein family 1
HLB42_RS11865	ENOG4108I7Y	domain protein
HLB42_RS11870	ENOG4105C8Y	Acetylornithine aminotransferase
HLB42_RS11880	ENOG41082J7	Rhodanese domain protein
HLB42_RS11885	ENOG4105VG1	fes assembly suf system protein
HLB42_RS11895	ENOG4105MCT	stage V sporulation protein S
HLB42_RS11910	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HLB42_RS11915	ENOG4108ME1	Peptidase M55 D-aminopeptidase
HLB42_RS11935	ENOG4105DGU	Histone deacetylase
HLB42_RS11960	ENOG4105WH1	Two component transcriptional regulator luxr family
HLB42_RS11965	ENOG4107SET	aldo keto reductase
HLB42_RS11985	ENOG41086EC	Modulates RecA activity (By similarity)
HLB42_RS11990	ENOG4108A5Q	Binds directly to 16S ribosomal RNA (By similarity)
HLB42_RS12000	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HLB42_RS12010	ENOG4105DR4	Methyltransferase
HLB42_RS12015	ENOG4108NGU	Transcriptional regulator
HLB42_RS12040	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HLB42_RS12055	ENOG4105BZU	Histidine kinase
HLB42_RS12060	ENOG4105F8C	transglutaminase domain-containing protein
HLB42_RS12065	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HLB42_RS12095	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HLB42_RS12120	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HLB42_RS12125	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HLB42_RS12130	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HLB42_RS12140	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
HLB42_RS12145	ENOG4105C31	Tryptophanyl-tRNA synthetase
HLB42_RS12155	ENOG4105CPQ	Dehydrogenase
HLB42_RS12170	ENOG4108UIH	futalosine nucleosidase
HLB42_RS12175	ENOG4105CHR	reductase
HLB42_RS12180	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HLB42_RS12185	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HLB42_RS12190	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HLB42_RS12205	ENOG4107QM5	aconitate hydratase
HLB42_RS12215	ENOG4105D60	lipoprotein releasing system transmembrane protein
HLB42_RS12225	ENOG4105CJN	penicillin-binding protein
HLB42_RS12235	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HLB42_RS12240	ENOG4108V6E	Cell division protein mraZ
HLB42_RS12245	ENOG4105M08	Membrane
HLB42_RS12255	ENOG4105KPY	Small multidrug resistance protein
HLB42_RS12275	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HLB42_RS12280	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
HLB42_RS12285	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HLB42_RS12290	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HLB42_RS12295	ENOG4108SJC	Membrane
HLB42_RS12310	ENOG4105C8N	cysteinyl-tRNA synthetase
HLB42_RS12320	ENOG4105EAD	ABC transporter
HLB42_RS12325	ENOG4107TXC	Transcriptional regulator
HLB42_RS12335	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HLB42_RS12345	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HLB42_RS12360	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HLB42_RS12365	ENOG4105CTU	Proline racemase
HLB42_RS12380	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
HLB42_RS12390	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
HLB42_RS12405	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HLB42_RS12410	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HLB42_RS12415	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HLB42_RS12425	ENOG4105DNP	FAD linked oxidase domain protein
HLB42_RS12440	ENOG4107RRU	Involved in both the arginine and lysine biosynthetic pathways (By similarity)
HLB42_RS12445	ENOG4105CZX	twitching motility protein
HLB42_RS12480	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HLB42_RS12510	ENOG4105CHH	sulfate transporter
HLB42_RS12520	ENOG4105EEQ	Na H antiporter
HLB42_RS12540	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HLB42_RS12545	ENOG4107ZIM	Dtdp-4-dehydrorhamnose 3,5-epimerase
HLB42_RS12565	ENOG4105D3Q	Sugar transferase
HLB42_RS12575	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HLB42_RS12650	ENOG4106TD9	Diguanylate cyclase
HLB42_RS12655	ENOG4105DU0	nucleoside hydrolase
HLB42_RS12675	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
HLB42_RS12690	ENOG4105CQB	FAD linked oxidase domain protein
HLB42_RS12695	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HLB42_RS12705	ENOG4105KZX	Pterin carbinolamine dehydratase
HLB42_RS12725	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HLB42_RS12730	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HLB42_RS12735	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HLB42_RS12750	ENOG4105BZU	Histidine kinase
HLB42_RS12760	ENOG4105WH1	Two component transcriptional regulator luxr family
HLB42_RS12775	ENOG4107JTW	chlorite dismutase
HLB42_RS12780	ENOG4105CPC	Aldo Keto reductase
HLB42_RS12785	ENOG4105ESP	cell wall surface anchor family protein
HLB42_RS12795	ENOG4108UYE	Lactoylglutathione lyase
HLB42_RS12800	ENOG4105BZU	Histidine kinase
HLB42_RS12805	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HLB42_RS12810	ENOG4105UIB	(ABC) transporter
HLB42_RS12825	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HLB42_RS12835	ENOG4105BZN	citrate synthase
HLB42_RS12870	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HLB42_RS12880	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HLB42_RS12885	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HLB42_RS12900	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HLB42_RS12915	ENOG4105JRK	feS assembly protein SufD
HLB42_RS12930	ENOG4105DIW	FeS assembly protein SUFB
HLB42_RS12935	ENOG4105C3K	feS assembly ATPase SufC
HLB42_RS12960	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
HLB42_RS12970	ENOG4105HMI	Membrane
HLB42_RS12980	ENOG4105CJ3	phosphate transporter
HLB42_RS12995	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HLB42_RS13015	ENOG4105D1F	ATP-binding protein
HLB42_RS13040	ENOG4105DHQ	Histidine kinase
HLB42_RS13055	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HLB42_RS13060	ENOG4105K46	50S ribosomal protein l27
HLB42_RS13065	ENOG4105CZN	Potassium uptake protein
HLB42_RS13080	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HLB42_RS13095	ENOG4105ZMH	deoxynucleoside kinase
HLB42_RS13120	ENOG4105C0H	protease
HLB42_RS13130	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HLB42_RS13150	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HLB42_RS13165	ENOG4105CGN	Glycosyl transferase (Group 1
HLB42_RS13175	ENOG4105D3Q	Sugar transferase
HLB42_RS13230	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
HLB42_RS13250	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HLB42_RS13260	ENOG4108IMY	Transcriptional regulator
HLB42_RS13270	ENOG4105CTD	carboxy-peptidase
HLB42_RS13285	ENOG4105C89	phosphohexose isomerase
HLB42_RS13300	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HLB42_RS13330	ENOG4105BZU	Histidine kinase
HLB42_RS13335	ENOG4105EMN	RNA polymerase sigma factor
HLB42_RS13345	ENOG4105ETE	Transcriptional regulator (LacI family
HLB42_RS13375	ENOG4105DU6	RNA polymerase
HLB42_RS13380	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
HLB42_RS13410	ENOG4105DBI	uridine monophosphokinase
HLB42_RS13415	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
HLB42_RS13420	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HLB42_RS13430	ENOG4105CNU	cell division protein FtsK
HLB42_RS13435	ENOG4108UKM	mov34 mpn pad-1 family protein
HLB42_RS13445	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HLB42_RS13450	ENOG4105CNI	cell division protein FtsW
HLB42_RS13480	ENOG4108IAJ	Nad-dependent epimerase dehydratase
HLB42_RS13490	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HLB42_RS13495	ENOG4105DAX	Pfam:DUF2983
HLB42_RS13520	ENOG4105MUA	Resistance protein
HLB42_RS13545	ENOG4108VCA	G U mismatch-specific DNA glycosylase
HLB42_RS13560	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
HLB42_RS13580	ENOG4105SFS	phosphoesterase RecJ domain protein
HLB42_RS13590	ENOG4105D9P	serine threonine protein kinase
HLB42_RS13595	ENOG4105EYH	Exonuclease
HLB42_RS13600	ENOG4107RH8	nuclease SbcCD subunit D
HLB42_RS13610	ENOG4105DZP	Membrane-associated zinc metalloprotease
HLB42_RS13615	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HLB42_RS13630	ENOG4105DER	m42 family
HLB42_RS13635	ENOG4107QN2	dihydrolipoyl dehydrogenase
HLB42_RS13640	ENOG4105DG6	mannose-6-phosphate isomerase
HLB42_RS13690	ENOG4105JFG	SpoIID LytB domain protein
HLB42_RS13700	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HLB42_RS13730	ENOG4105NVB	glycoside hydrolase, family 19
HLB42_RS13950	ENOG4107RHI	Cytosine-specific methyltransferase
HLB42_RS13995	ENOG4105C0P	Mg chelatase subunit ChlI
HLB42_RS14015	ENOG4107SBK	Acetylornithine deacetylase
HLB42_RS14020	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HLB42_RS14040	ENOG4107QPV	Serine Threonine protein kinase
HLB42_RS14055	ENOG4105D1H	recombination factor protein RarA
HLB42_RS14070	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HLB42_RS14075	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HLB42_RS14080	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HLB42_RS14095	ENOG4105CHR	reductase
HLB42_RS14100	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HLB42_RS14105	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HLB42_RS14110	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HLB42_RS14120	ENOG4108Z6Z	Transcriptional regulator
HLB42_RS14125	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HLB42_RS14135	ENOG4105BZ7	extracellular solute-binding protein family 1
HLB42_RS14145	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS14150	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
HLB42_RS14155	ENOG4105CTD	carboxy-peptidase
HLB42_RS14160	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HLB42_RS14165	ENOG4105DFF	Rod shape-determining protein mreb
HLB42_RS14170	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HLB42_RS14185	ENOG4108ZJ4	polysaccharide deacetylase
HLB42_RS14200	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HLB42_RS14215	ENOG4105DBV	ornithine carbamoyltransferase
HLB42_RS14220	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HLB42_RS14225	ENOG4105KNI	merR family transcriptional Regulator
HLB42_RS14230	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HLB42_RS14235	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HLB42_RS14255	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HLB42_RS14270	ENOG4105KHC	sulfurtransferase
HLB42_RS14285	ENOG4105CGK	Exodeoxyribonuclease III
HLB42_RS14290	ENOG4105DKK	Benzoate
HLB42_RS14295	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HLB42_RS14305	ENOG4105T2N	Domain of unknown function (DUF2382)
HLB42_RS14310	ENOG4105E3H	phosphoglycerate mutase
HLB42_RS14335	ENOG4105BZ7	extracellular solute-binding protein family 1
HLB42_RS14340	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
HLB42_RS14345	ENOG4105DRS	transport system, permease
HLB42_RS14365	ENOG4105BZU	Histidine kinase
HLB42_RS14370	ENOG4105CDY	transcriptional regulatory protein
HLB42_RS14385	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HLB42_RS14390	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HLB42_RS14410	ENOG4105EV4	Multidrug resistance protein mdtH
HLB42_RS14415	ENOG4105CNI	cell division protein FtsW
HLB42_RS14430	ENOG4108CHF	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
HLB42_RS14440	ENOG4105DD7	kinase (PfkB family
HLB42_RS14450	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
HLB42_RS14455	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HLB42_RS14460	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HLB42_RS14465	ENOG4105BZU	Histidine kinase
HLB42_RS14470	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HLB42_RS14480	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HLB42_RS14535	ENOG4105CKK	Glycosyl transferase, family 2
HLB42_RS14560	ENOG4107VMU	Membrane
HLB42_RS14570	ENOG4105HHA	aminodeoxychorismate lyase
HLB42_RS14575	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HLB42_RS14580	ENOG4107ZYJ	bioY protein
HLB42_RS14585	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HLB42_RS14615	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
HLB42_RS14630	ENOG4107S1Q	Phosphatase
HLB42_RS14640	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HLB42_RS14645	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HLB42_RS14655	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HLB42_RS14665	ENOG4107QSN	dihydrolipoamide acetyltransferase
HLB42_RS14670	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HLB42_RS14720	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HLB42_RS14725	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HLB42_RS14730	ENOG4107RSM	transcriptional regulator
HLB42_RS14740	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
HLB42_RS14755	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
HLB42_RS14765	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
HLB42_RS14770	ENOG4105C8V	SAICAR synthetase
HLB42_RS14790	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HLB42_RS14795	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HLB42_RS14800	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HLB42_RS14805	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
HLB42_RS14810	ENOG4107QHF	type ii secretion system protein e
HLB42_RS14815	ENOG4105CZX	twitching motility protein
HLB42_RS14820	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HLB42_RS14825	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HLB42_RS14830	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HLB42_RS14840	ENOG4108Z5V	transcriptional regulator, merr family
HLB42_RS14845	ENOG4105CN5	Metallo-Beta-Lactamase
HLB42_RS14850	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HLB42_RS14855	ENOG4105BZU	Histidine kinase
HLB42_RS14875	ENOG41081FY	multiple antibiotic resistance (MarC)-related
HLB42_RS14910	ENOG4105BZN	citrate synthase
HLB42_RS14915	ENOG4108W6C	Dehydrogenase
HLB42_RS14930	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HLB42_RS14960	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HLB42_RS14970	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
HLB42_RS14975	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HLB42_RS14980	ENOG4108FXY	Cys/Met metabolism PLP-dependent enzyme
HLB42_RS14990	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HLB42_RS15005	ENOG4105C5H	ABC transporter
HLB42_RS15015	ENOG4105CC5	ABC transporter
HLB42_RS15020	ENOG4105DIK	(ABC) transporter
HLB42_RS15030	ENOG4105DE4	1-phosphofructokinase
HLB42_RS15050	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
HLB42_RS15055	ENOG4107YEI	lmbE family
HLB42_RS15060	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HLB42_RS15065	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HLB42_RS15070	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HLB42_RS15095	ENOG4105K4I	Scp-like extracellular
HLB42_RS15105	ENOG4105E0X	reductase
HLB42_RS15115	ENOG4105C34	Pseudouridine synthase
HLB42_RS15130	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HLB42_RS15135	ENOG4105K6V	RNA polymerase
HLB42_RS15140	ENOG4105RNG	membrane
HLB42_RS15155	ENOG4105WJV	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS15160	ENOG4108IJ8	ABC transporter
HLB42_RS15165	ENOG4107T5X	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS15170	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
HLB42_RS15190	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HLB42_RS15195	ENOG4105E66	phosphoriboisomerase A
HLB42_RS15205	ENOG4105C7Z	Conserved Protein
HLB42_RS15220	ENOG41080UQ	Transcriptional regulator
HLB42_RS15225	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HLB42_RS15260	ENOG4105K64	Glycosyl transferase, family 2
HLB42_RS15265	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HLB42_RS15270	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HLB42_RS15295	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HLB42_RS15300	ENOG4105PSV	Polysaccharide Biosynthesis Protein
HLB42_RS15330	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HLB42_RS15340	ENOG4105EEI	dihydropteroate synthase
HLB42_RS15345	ENOG4105M03	Domain of unknown function (DUF955)
HLB42_RS15365	ENOG4105D9P	serine threonine protein kinase
HLB42_RS15375	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
HLB42_RS15395	ENOG4105C88	aminopeptidase
HLB42_RS15400	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HLB42_RS15405	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HLB42_RS15410	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
HLB42_RS15420	ENOG4105D3Q	Sugar transferase
HLB42_RS15425	ENOG4107ZT3	family UPF0126
HLB42_RS15440	ENOG4105DU1	integral membrane protein, terc
HLB42_RS15460	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
HLB42_RS15465	ENOG4105CAK	Cell division ATP-binding protein ftsE
HLB42_RS15470	ENOG4105CN1	protease
HLB42_RS15475	ENOG41082AW	Binds together with S18 to 16S ribosomal RNA (By similarity)
HLB42_RS15480	ENOG4107YH6	single-stranded DNA-binding protein
HLB42_RS15485	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HLB42_RS15490	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HLB42_RS15505	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
HLB42_RS15550	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HLB42_RS15555	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
HLB42_RS15575	ENOG4105BZU	Histidine kinase
HLB42_RS15580	ENOG4105E2X	shikimate dehydrogenase
HLB42_RS15590	ENOG41080V7	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HLB42_RS15595	ENOG4107YR5	Diacylglycerol kinase
HLB42_RS15610	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HLB42_RS15625	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HLB42_RS15630	ENOG4105BZU	Histidine kinase
HLB42_RS15640	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HLB42_RS15655	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLB42_RS15660	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HLB42_RS15670	ENOG4105VG0	50S ribosomal protein l34
HLB42_RS15680	ENOG41060W2	glyoxylate carboligase
HLB42_RS15685	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
HLB42_RS15690	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HLB42_RS15705	ENOG41073R8	VanW family
HLB42_RS15715	ENOG4105DTQ	mandelate racemase muconate lactonizing
HLB42_RS15725	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HLB42_RS15740	ENOG4105DGU	Histone deacetylase
HLB42_RS15750	ENOG4105D7N	magnesium and cobalt transport protein CorA
HLB42_RS15760	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HLB42_RS15785	ENOG4105CH7	arginosuccinase
HLB42_RS15795	ENOG4105CDH	Citrulline--aspartate ligase
HLB42_RS15815	ENOG4105C32	Amino acid ABC transporter (Permease)
HLB42_RS15820	ENOG4108HWW	ABC transporter
HLB42_RS15825	ENOG4105C0Z	ABC transporter
HLB42_RS15830	ENOG4108IV0	ABC, transporter
HLB42_RS15840	ENOG4105C31	Tryptophanyl-tRNA synthetase
HLB42_RS15850	ENOG4105E8R	UPF0173 metal-dependent hydrolase
HLB42_RS15895	ENOG4106H78	methyltransferase
HLB42_RS15900	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HLB42_RS15910	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HLB42_RS15915	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HLB42_RS15935	ENOG4105C3M	thioredoxin reductase
HLB42_RS15950	ENOG4107RT4	flavin reductase domain protein
HLB42_RS15960	ENOG4108I5C	dEAD DEAH box helicase
HLB42_RS15965	ENOG4105CHM	Aminotransferase
HLB42_RS15975	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
HLB42_RS15995	ENOG4107YAU	phenylacetic acid degradation protein
HLB42_RS16000	ENOG4107VFM	Dehydrogenase
HLB42_RS16010	ENOG4108UT2	hemolysin iii
HLB42_RS16015	ENOG4105DSE	periplasmic solute binding protein
HLB42_RS16020	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HLB42_RS16025	ENOG4105CHR	reductase
HLB42_RS16045	ENOG4105CSR	polyphosphate kinase 2
HLB42_RS16065	ENOG4105C26	Dehydrogenase
HLB42_RS16090	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HLB42_RS16095	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HLB42_RS16100	ENOG4105C1G	acyl-Coa dehydrogenase
HLB42_RS16105	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS16110	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS16125	ENOG4105EMU	Dehydrogenase
HLB42_RS16130	ENOG4105CTD	carboxy-peptidase
HLB42_RS16135	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HLB42_RS16140	ENOG4105CHR	reductase
HLB42_RS16170	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS16175	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS16180	ENOG4105DEF	Extracellular solute-binding protein, family 5
HLB42_RS16190	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HLB42_RS16200	ENOG4105ZU5	s-layer protein
HLB42_RS16205	ENOG4105E39	Enoyl-CoA hydratase
HLB42_RS16220	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HLB42_RS16235	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HLB42_RS16240	ENOG4105D6E	homoserine dehydrogenase
HLB42_RS16250	ENOG4105K8N	protein family UPF0079, ATPase
HLB42_RS16315	ENOG4108UXE	Protein tyrosine phosphatase
HLB42_RS16325	ENOG4107WAU	Protein tyrosine phosphatase
HLB42_RS16330	ENOG4105KBH	arsR family transcriptional regulator
HLB42_RS16335	ENOG4105VPX	protein, conserved in bacteria
HLB42_RS16340	ENOG4107TPS	domain protein
HLB42_RS16490	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
HLB42_RS16515	ENOG4105C6K	Malic enzyme
HLB42_RS16520	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HLB42_RS16530	ENOG4105ECP	epimerase
HLB42_RS16535	ENOG4105C6T	cysteine synthase
HLB42_RS16550	ENOG4107QP3	malate synthase g
HLB42_RS16555	ENOG4107HP6	Transcriptional regulator
HLB42_RS16560	ENOG4107R9S	Malate synthase
HLB42_RS16570	ENOG4105CD3	dihydroorotase
HLB42_RS16580	ENOG4107R1I	NAD-dependent malic enzyme
HLB42_RS16585	ENOG4105ECB	domain protein
HLB42_RS16595	ENOG4105JD4	ATPase yjob
HLB42_RS16605	ENOG4105CSU	acyl-Coa dehydrogenase
HLB42_RS16610	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HLB42_RS16630	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
HLB42_RS16635	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HLB42_RS16640	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
HLB42_RS16645	ENOG4105C0A	alcohol dehydrogenase
HLB42_RS16650	ENOG410850P	UPF0102 protein
HLB42_RS16655	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HLB42_RS16695	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HLB42_RS16705	ENOG4105C9Q	fumarate hydratase class II
HLB42_RS16720	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HLB42_RS16730	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HLB42_RS16740	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HLB42_RS16745	ENOG4105C2W	permease
HLB42_RS16760	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
HLB42_RS16765	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HLB42_RS16790	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
HLB42_RS16795	ENOG41073R8	VanW family
HLB42_RS16800	ENOG4105FA0	parb-like partition protein
HLB42_RS16805	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
HLB42_RS16810	ENOG4107YI1	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HLB42_RS16820	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HLB42_RS16830	ENOG4107SUU	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
HLB42_RS16835	ENOG4105CPP	Dehydrogenase, E1 component
HLB42_RS16845	ENOG4105C7S	Dehydrogenase
HLB42_RS16855	ENOG4105ETX	regulatoR
HLB42_RS16890	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS16895	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS16915	ENOG4105ETE	Transcriptional regulator (LacI family
HLB42_RS16930	ENOG4105DRS	transport system, permease
HLB42_RS16980	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
HLB42_RS17040	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
HLB42_RS17060	ENOG4105E5Q	amino acid AbC transporter
HLB42_RS17080	ENOG4105ESP	cell wall surface anchor family protein
HLB42_RS17085	ENOG41067TZ	transcriptional regulator, MarR family
HLB42_RS17095	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
HLB42_RS17100	ENOG4105FBA	Phospholipase Carboxylesterase
HLB42_RS17135	ENOG4105CS1	NAD(P)H quinone oxidoreductase
HLB42_RS17145	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
HLB42_RS17155	ENOG4107RQ0	Maleylacetate reductase
HLB42_RS17195	ENOG4105C59	p-type ATPase
HLB42_RS17220	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HLB42_RS17240	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HLB42_RS17260	ENOG4105BZU	Histidine kinase
HLB42_RS17290	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
HLB42_RS17295	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HLB42_RS17300	ENOG4106F59	XRE family Transcriptional regulator
HLB42_RS17310	ENOG4105BZU	Histidine kinase
HLB42_RS17335	ENOG4105BZU	Histidine kinase
HLB42_RS17340	ENOG4105WH1	Two component transcriptional regulator luxr family
HLB42_RS17375	ENOG4105WH1	Two component transcriptional regulator luxr family
HLB42_RS17415	ENOG4105BZU	Histidine kinase
HLB42_RS17425	ENOG4105BZU	Histidine kinase
HLB42_RS17445	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HLB42_RS17450	ENOG4105BZU	Histidine kinase
HLB42_RS17465	ENOG4108C33	Resolvase
HLB42_RS17470	ENOG4105BZU	Histidine kinase
HLB42_RS17485	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HLB42_RS17510	ENOG4105BZU	Histidine kinase
HLB42_RS17525	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HLB42_RS17550	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HLB42_RS17575	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
HLB42_RS17610	ENOG4105DEF	Extracellular solute-binding protein, family 5
HLB42_RS17615	ENOG4105DEF	Extracellular solute-binding protein, family 5
HLB42_RS17625	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HLB42_RS17660	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
HLB42_RS17665	ENOG4105DD7	kinase (PfkB family
HLB42_RS17670	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HLB42_RS17680	ENOG4105C8U	phosphate abc transporter
HLB42_RS17685	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
HLB42_RS17695	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
HLB42_RS17705	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HLB42_RS17715	ENOG4105C08	Histidine kinase
HLB42_RS17720	ENOG4105WH1	Two component transcriptional regulator luxr family
HLB42_RS17775	ENOG4105CMM	transposase
HLB42_RS17805	ENOG4108JJA	ABC, transporter
HLB42_RS17825	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HLB42_RS17830	ENOG4105DE4	1-phosphofructokinase
HLB42_RS17835	ENOG4105DM4	PTS System
HLB42_RS17840	ENOG4105E0A	ABC, transporter
HLB42_RS17845	ENOG4108U1V	ABC transporter, permease
HLB42_RS17850	ENOG4108HUF	Transporter
HLB42_RS17855	ENOG4105DQ5	transport system permease protein
HLB42_RS17865	ENOG4105J76	Periplasmic binding protein
HLB42_RS17880	ENOG4105WEF	catalase
HLB42_RS17895	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
HLB42_RS17905	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
HLB42_RS17910	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
HLB42_RS17925	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
HLB42_RS17930	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HLB42_RS17945	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
HLB42_RS17955	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HLB42_RS17975	ENOG4105BZU	Histidine kinase
HLB42_RS18080	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HLB42_RS18095	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HLB42_RS18125	ENOG4105C37	(CBS) domain
HLB42_RS18180	ENOG4105K6V	RNA polymerase
HLB42_RS18300	ENOG410825M	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HLB42_RS18330	ENOG41089N3	Inherit from COG: cobyrinic Acid a,c-diamide synthase
HLB42_RS18335	ENOG4105FA0	parb-like partition protein
HLB42_RS18400	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
HLB42_RS18465	ENOG4105CVR	type I restriction-modification system
HLB42_RS18470	ENOG4105DFS	Conserved Protein
HLB42_RS18505	ENOG4105CMM	transposase
HLB42_RS18600	ENOG41082BM	Transcriptional regulator, arsr family
HLB42_RS18605	ENOG4105F6J	Alpha beta hydrolase fold
HLB42_RS18635	ENOG4105C7W	Xanthine dehydrogenase
HLB42_RS18645	ENOG4107QUY	Guanine deaminase
HLB42_RS18650	ENOG4105C7N	Xanthine uracil vitamin C permease
HLB42_RS18655	ENOG4105CEY	Amp-dependent synthetase and ligase
HLB42_RS18660	ENOG4105K70	DNA-binding protein
HLB42_RS18665	ENOG4105CJW	magnesium transporter
HLB42_RS18680	ENOG4107XKF	NMT1 THI5 Like Domain Protein
HLB42_RS18685	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS18690	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS18705	ENOG4107SJI	Dehydrogenase
HLB42_RS18710	ENOG4105BZ8	glutamate synthase
HLB42_RS18715	ENOG4108VCT	Sulfite exporter TauE/SafE
HLB42_RS18720	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
HLB42_RS18730	ENOG4107TPS	domain protein
HLB42_RS18735	ENOG41082J7	Rhodanese domain protein
HLB42_RS18740	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HLB42_RS18745	ENOG4105VPX	protein, conserved in bacteria
HLB42_RS18765	ENOG4108M8H	domain protein
HLB42_RS18775	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HLB42_RS18780	ENOG410620I	Diguanylate cyclase
HLB42_RS18790	ENOG4106A3M	Cytochrome p-450
HLB42_RS18795	ENOG4105CHR	reductase
HLB42_RS18800	ENOG41080XP	Cbs domain
HLB42_RS18805	ENOG4108TM9	integral membrane protein
HLB42_RS18840	ENOG4105K63	Thioredoxin
HLB42_RS18850	ENOG4105E3B	Multicopper oxidase
HLB42_RS18895	ENOG4108IND	Tetr family transcriptional regulator
HLB42_RS18920	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS18925	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS18930	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
HLB42_RS18980	ENOG4105CHU	acetyl-coa acetyltransferase
HLB42_RS18985	ENOG4105CEY	Amp-dependent synthetase and ligase
HLB42_RS18995	ENOG4105C1G	acyl-Coa dehydrogenase
HLB42_RS19000	ENOG4105DRR	Transcriptional regulator, GntR family
HLB42_RS19005	ENOG4105CPI	Metal Dependent Phosphohydrolase
HLB42_RS19015	ENOG4105BZU	Histidine kinase
HLB42_RS19045	ENOG4108UMN	azlc family
HLB42_RS19055	ENOG4105BZ1	(ABC) transporter
HLB42_RS19060	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HLB42_RS19090	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HLB42_RS19095	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS19105	ENOG4107QRA	Extracellular solute-binding protein, family 5
HLB42_RS19110	ENOG4107QRA	Extracellular solute-binding protein, family 5
HLB42_RS19120	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HLB42_RS19135	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HLB42_RS19145	ENOG4105CBS	Chea signal transduction histidine kinase
HLB42_RS19150	ENOG4108NVR	Methyl-accepting chemotaxis
HLB42_RS19165	ENOG4105M3Z	response regulator
HLB42_RS19185	ENOG4105CC9	acyl-Coa dehydrogenase
HLB42_RS19200	ENOG4105CHR	reductase
HLB42_RS19240	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HLB42_RS19250	ENOG4105C1G	acyl-Coa dehydrogenase
HLB42_RS19260	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HLB42_RS19285	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS19300	ENOG4107RAQ	aminopeptidase
HLB42_RS19305	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HLB42_RS19310	ENOG4105DC7	peptidase M24
HLB42_RS19320	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HLB42_RS19335	ENOG4105CMM	transposase
HLB42_RS19350	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
HLB42_RS19355	ENOG4105DRS	transport system, permease
HLB42_RS19365	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
HLB42_RS19370	ENOG4107SQI	penicillin amidase
HLB42_RS19405	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HLB42_RS19415	ENOG4105DIA	mandelate racemase muconate lactonizing
HLB42_RS19420	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HLB42_RS19445	ENOG4105BZP	glycoside hydrolase 15-related
HLB42_RS19485	ENOG4105XEA	Tetr family transcriptional regulator
HLB42_RS19525	ENOG4105H3G	oxidoreductase
HLB42_RS19535	ENOG4105BZU	Histidine kinase
HLB42_RS19555	ENOG4105C26	Dehydrogenase
HLB42_RS19560	ENOG4105EFA	4-hydroxyphenylacetate
HLB42_RS19595	ENOG41089N3	Inherit from COG: cobyrinic Acid a,c-diamide synthase
HLB42_RS19600	ENOG4105CS2	ec 3.2.1.21
HLB42_RS19605	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HLB42_RS19610	ENOG4105CPQ	Dehydrogenase
HLB42_RS19615	ENOG4105DEI	Mannitol dehydrogenase
HLB42_RS19620	ENOG4107Z1W	Fructose transport system kinase
HLB42_RS19640	ENOG4105ETE	Transcriptional regulator (LacI family
HLB42_RS19655	ENOG4105BZP	glycoside hydrolase 15-related
HLB42_RS19685	ENOG41065KQ	synthase
HLB42_RS19690	ENOG4108IV0	ABC, transporter
HLB42_RS19695	ENOG4105C0Z	ABC transporter
HLB42_RS19720	ENOG4105CSU	acyl-Coa dehydrogenase
HLB42_RS19730	ENOG4105CE4	GlcNAc 6-P deacetylase
HLB42_RS19735	ENOG4105BZU	Histidine kinase
HLB42_RS19740	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HLB42_RS19750	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
HLB42_RS19755	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
HLB42_RS19760	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
HLB42_RS19785	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HLB42_RS19790	ENOG4105QAX	Iron-sulfur
HLB42_RS19825	ENOG4105CHR	reductase
HLB42_RS19830	ENOG4105JSC	dimethylmenaquinone methyltransferase
HLB42_RS19840	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HLB42_RS19845	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HLB42_RS19850	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HLB42_RS19870	ENOG4107HP6	Transcriptional regulator
HLB42_RS19875	ENOG4105DC7	peptidase M24
HLB42_RS19880	ENOG4105CMG	Carbohydrate kinase
HLB42_RS19890	ENOG4105C2J	ABC transporter
HLB42_RS19895	ENOG4108HWW	ABC transporter
HLB42_RS19900	ENOG4105DFW	ABC transporter
HLB42_RS19905	ENOG4105ETE	Transcriptional regulator (LacI family
HLB42_RS19910	ENOG4105CIB	oxidoreductase Domain protein
HLB42_RS19915	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
HLB42_RS19920	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HLB42_RS19925	ENOG4105CNN	ABC, transporter
HLB42_RS19935	ENOG4108J2R	molybdopterin oxidoreductase
HLB42_RS19945	ENOG4105C26	Dehydrogenase
HLB42_RS19950	ENOG4105C8Y	Acetylornithine aminotransferase
HLB42_RS19970	ENOG4105P4J	Allophanate hydrolase, subunit 1
HLB42_RS19980	ENOG4108DN8	FAD dependent oxidoreductase
HLB42_RS19990	ENOG4105DZS	Phenylacetate-CoA ligase
HLB42_RS19995	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HLB42_RS20000	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HLB42_RS20005	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HLB42_RS20010	ENOG4107RHR	regulatoR
HLB42_RS20015	ENOG4105DN3	alpha-2-macroglobulin domain protein
HLB42_RS20025	ENOG4105CPQ	Dehydrogenase
HLB42_RS20035	ENOG4105F6J	Alpha beta hydrolase fold
HLB42_RS20045	ENOG4105KDM	Diguanylate cyclase with gaf sensor
HLB42_RS20050	ENOG4105C4R	Atp-dependent dna helicase
HLB42_RS20235	ENOG4107S1Q	Phosphatase
HLB42_RS20245	ENOG4105C0H	protease
HLB42_RS20265	ENOG4105CY0	Metallo-Beta-Lactamase
HLB42_RS20310	ENOG4105WH1	Two component transcriptional regulator luxr family
HLB42_RS20315	ENOG4105BZU	Histidine kinase
HLB42_RS20355	ENOG4105CN1	protease
HLB42_RS20365	ENOG4108C33	Resolvase
HLB42_RS20375	ENOG4105MZU	cell filamentation protein
HLB42_RS20555	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
HLB42_RS20575	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
HLB42_RS20580	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HLB42_RS20615	ENOG4105FA0	parb-like partition protein
HLB42_RS20770	ENOG4105T2N	Domain of unknown function (DUF2382)
HLB42_RS20785	ENOG4105KDM	Diguanylate cyclase with gaf sensor
HLB42_RS20795	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HLB42_RS20820	ENOG4105CPI	Metal Dependent Phosphohydrolase
HLB42_RS20830	ENOG4108IUW	ABC transporter
HLB42_RS20850	ENOG4105CKW	Inner membrane protein yedI
HLB42_RS20855	ENOG4105KT7	mgtC SapB transporter
HLB42_RS20880	ENOG4105C59	p-type ATPase
HLB42_RS20910	ENOG4105E4C	Lytic transglycosylase catalytic
HLB42_RS20920	ENOG4105C59	p-type ATPase
HLB42_RS20960	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HLB42_RS20970	ENOG4105BZU	Histidine kinase
HLB42_RS20975	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HLB42_RS20980	ENOG4107QX9	Thiol disulfide interChange protein
HLB42_RS21000	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HLB42_RS21055	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HLB42_RS21065	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HLB42_RS21090	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HLB42_RS21095	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HLB42_RS21125	ENOG4105C59	p-type ATPase
HLB42_RS21140	ENOG41082JC	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HLB42_RS21165	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HLB42_RS21170	ENOG4108K5P	(LipO)protein
HLB42_RS21200	ENOG4107YCR	Transcriptional regulator, ARSR family
HLB42_RS21220	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
HLB42_RS21225	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
HLB42_RS21415	ENOG4105CUZ	uba thif-type nad fad binding protein
HLB42_RS21455	ENOG4105NVB	glycoside hydrolase, family 19
HLB42_RS21675	ENOG4107RHI	Cytosine-specific methyltransferase
HLB42_RS21725	ENOG4105KHS	type IV fimbrial pilin protein
HLB42_RS21775	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
HLB42_RS21790	ENOG4105KDM	Diguanylate cyclase with gaf sensor
HLB42_RS21855	ENOG4105CPI	Metal Dependent Phosphohydrolase
HLB42_RS21925	ENOG4108SHN	Glycosyl transferase, family 2