locus-tag	class	description
QR90_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
QR90_RS00010	COG0592	DNA-directed DNA polymerase activity
QR90_RS00015	COG0148	phosphopyruvate hydratase activity
QR90_RS00020	COG0469	pyruvate kinase activity
QR90_RS00025	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
QR90_RS00045	COG1758	RNA polymerase activity
QR90_RS00050	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
QR90_RS00055	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
QR90_RS00065	COG0443	Heat shock 70 kDa protein
QR90_RS00070	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
QR90_RS00075	COG4628	conserved protein (DUF2132)
QR90_RS00080	COG0484	heat shock protein binding
QR90_RS00085	COG5002	protein histidine kinase activity
QR90_RS00110	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
QR90_RS00165	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
QR90_RS00220	COG0633	Ferredoxin
QR90_RS00225	COG0442	prolyl-tRNA aminoacylation
QR90_RS00255	COG2819	hydrolase of the alpha beta superfamily
QR90_RS00265	COG2746	aminoglycoside 3-N-acetyltransferase activity
QR90_RS00275	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
QR90_RS00280	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
QR90_RS00290	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
QR90_RS00305	COG1024	Enoyl-CoA hydratase
QR90_RS00310	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
QR90_RS00335	COG0227	Belongs to the bacterial ribosomal protein bL28 family
QR90_RS00340	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
QR90_RS00345	COG1854	S-ribosylhomocysteine lyase activity
QR90_RS00365	COG0343	queuine tRNA-ribosyltransferase activity
QR90_RS00370	COG3206	protein involved in exopolysaccharide biosynthesis
QR90_RS00375	COG1227	inorganic diphosphatase activity
QR90_RS00380	COG0285	dihydrofolate synthase activity
QR90_RS00395	COG4106	trans-aconitate 2-methyltransferase activity
QR90_RS00435	COG0668	transmembrane transport
QR90_RS00445	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
QR90_RS00445	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
QR90_RS00520	COG1940	carbohydrate kinase activity
QR90_RS00530	COG0459	protein refolding
QR90_RS00535	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
QR90_RS00540	COG3706	GGDEF domain
QR90_RS00580	COG0612	Peptidase, M16
QR90_RS00585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
QR90_RS00600	COG1394	ATPase activity, coupled to movement of substances
QR90_RS00605	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
QR90_RS00610	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
QR90_RS00615	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
QR90_RS00620	COG1527	subunit (C
QR90_RS00625	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
QR90_RS00630	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
QR90_RS00635	COG1269	ATP hydrolysis coupled proton transport
QR90_RS00660	COG0291	Belongs to the bacterial ribosomal protein bL35 family
QR90_RS00665	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
QR90_RS00670	COG2188	Transcriptional regulator
QR90_RS00675	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
QR90_RS00680	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
QR90_RS00685	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
QR90_RS00690	COG0586	Pfam SNARE associated Golgi protein
QR90_RS00695	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
QR90_RS00700	COG0483	inositol monophosphate 1-phosphatase activity
QR90_RS00715	COG1994	Peptidase M50
QR90_RS00725	COG0617	tRNA 3'-terminal CCA addition
QR90_RS00730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
QR90_RS00740	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
QR90_RS00750	COG2197	response regulator
QR90_RS00785	COG0726	polysaccharide deacetylase
QR90_RS00800	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
QR90_RS00815	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
QR90_RS00825	COG0587	DNA-directed DNA polymerase activity
QR90_RS00845	COG0824	Thioesterase
QR90_RS00850	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
QR90_RS00880	COG0717	Belongs to the dCTP deaminase family
QR90_RS00925	COG2130	NADP-dependent
QR90_RS00940	COG3842	ATPase activity
QR90_RS00990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
QR90_RS01030	COG0222	ribosome binding
QR90_RS01035	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
QR90_RS01040	COG0081	regulation of translation
QR90_RS01045	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
QR90_RS01050	COG0250	Participates in transcription elongation, termination and antitermination
QR90_RS01055	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
QR90_RS01060	COG0267	Belongs to the bacterial ribosomal protein bL33 family
QR90_RS01095	COG1132	(ABC) transporter
QR90_RS01100	COG1132	(ABC) transporter
QR90_RS01145	COG1028	Short-chain dehydrogenase reductase Sdr
QR90_RS01150	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
QR90_RS01155	COG0702	epimerase
QR90_RS01160	COG1012	belongs to the aldehyde dehydrogenase family
QR90_RS01160	COG2030	dehydratase
QR90_RS01180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
QR90_RS01185	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
QR90_RS01205	COG0305	Participates in initiation and elongation during chromosome replication
QR90_RS01210	COG2165	general secretion pathway protein
QR90_RS01225	COG3152	Membrane
QR90_RS01230	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
QR90_RS01235	COG0140	phosphoribosyl-ATP diphosphatase activity
QR90_RS01235	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
QR90_RS01240	COG0107	imidazoleglycerol-phosphate synthase activity
QR90_RS01280	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
QR90_RS01285	COG0540	Belongs to the ATCase OTCase family
QR90_RS01295	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
QR90_RS01305	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
QR90_RS01320	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
QR90_RS01330	COG0686	Belongs to the AlaDH PNT family
QR90_RS01350	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
QR90_RS01385	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
QR90_RS01395	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
QR90_RS01410	COG0312	modulator of DNA gyrase
QR90_RS01440	COG0564	pseudouridine synthase activity
QR90_RS01445	COG1293	RNA-binding protein homologous to eukaryotic snRNP
QR90_RS01450	COG2226	methyltransferase
QR90_RS01485	COG0557	exoribonuclease II activity
QR90_RS01505	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
QR90_RS01530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
QR90_RS01540	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
QR90_RS01550	COG0284	orotidine-5'-phosphate decarboxylase activity
QR90_RS01565	COG1959	2 iron, 2 sulfur cluster binding
QR90_RS01590	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
QR90_RS01620	COG3206	protein involved in exopolysaccharide biosynthesis
QR90_RS01620	COG0489	protein tyrosine kinase activity
QR90_RS01645	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
QR90_RS01650	COG1085	galactose-1-phosphate uridylyltransferase
QR90_RS01655	COG3345	alpha-galactosidase
QR90_RS01665	COG0395	ABC-type sugar transport system, permease component
QR90_RS01675	COG1653	transport
QR90_RS01680	COG1349	DNA-binding transcription factor activity
QR90_RS01695	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
QR90_RS01700	COG0424	maF-like protein
QR90_RS01705	COG1792	Involved in formation and maintenance of cell shape
QR90_RS01740	COG2197	response regulator
QR90_RS01765	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
QR90_RS01785	COG0601	transmembrane transport
QR90_RS01790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
QR90_RS01795	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
QR90_RS01800	COG2339	peptidase activity
QR90_RS01805	COG0314	molybdopterin synthase activity
QR90_RS01820	COG0723	plastoquinol--plastocyanin reductase activity
QR90_RS01845	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
QR90_RS01850	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
QR90_RS01870	COG2311	Membrane
QR90_RS01875	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
QR90_RS01885	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
QR90_RS01895	COG3273	potassium ion transport
QR90_RS01895	COG0471	metal ion transport
QR90_RS01900	COG1607	acyl-coa hydrolase
QR90_RS01910	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
QR90_RS01915	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
QR90_RS01925	COG0666	response to abiotic stimulus
QR90_RS01940	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
QR90_RS01950	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
QR90_RS01955	COG0336	Belongs to the RNA methyltransferase TrmD family
QR90_RS01960	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
QR90_RS01965	COG1837	Belongs to the UPF0109 family
QR90_RS01970	COG0228	four-way junction DNA binding
QR90_RS01995	COG1116	anion transmembrane transporter activity
QR90_RS02000	COG0697	spore germination
QR90_RS02015	COG1803	Methylglyoxal synthase
QR90_RS02020	COG1040	competence protein
QR90_RS02050	COG1051	belongs to the nudix hydrolase family
QR90_RS02050	COG1056	cytidyltransferase-related domain
QR90_RS02055	COG0657	acetylesterase activity
QR90_RS02060	COG1832	CoA-binding protein
QR90_RS02065	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
QR90_RS02125	COG2226	methyltransferase
QR90_RS02140	COG2315	Protein conserved in bacteria
QR90_RS02160	COG1737	Transcriptional regulator
QR90_RS02170	COG1175	transmembrane transport
QR90_RS02175	COG0395	ABC-type sugar transport system, permease component
QR90_RS02185	COG1472	Belongs to the glycosyl hydrolase 3 family
QR90_RS02220	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
QR90_RS02235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
QR90_RS02285	COG0454	-acetyltransferase
QR90_RS02285	COG0456	acetyltransferase
QR90_RS02290	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
QR90_RS02315	COG0785	Cytochrome C biogenesis protein
QR90_RS02320	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
QR90_RS02330	COG0512	Glutamine amidotransferase of anthranilate synthase
QR90_RS02335	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
QR90_RS02340	COG0473	3-isopropylmalate dehydrogenase activity
QR90_RS02350	COG1522	sequence-specific DNA binding
QR90_RS02365	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
QR90_RS02375	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
QR90_RS02380	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
QR90_RS02390	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
QR90_RS02395	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
QR90_RS02415	COG1404	Belongs to the peptidase S8 family
QR90_RS02420	COG4932	domain protein
QR90_RS02425	COG1404	Belongs to the peptidase S8 family
QR90_RS02450	COG0747	negative chemotaxis
QR90_RS02460	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
QR90_RS02470	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
QR90_RS02485	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
QR90_RS02490	COG2046	Belongs to the sulfate adenylyltransferase family
QR90_RS02495	COG0175	sulfate reduction
QR90_RS02500	COG0529	Catalyzes the synthesis of activated sulfate
QR90_RS02505	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
QR90_RS02515	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
QR90_RS02520	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
QR90_RS02525	COG0586	Pfam SNARE associated Golgi protein
QR90_RS02535	COG1073	alpha beta
QR90_RS02555	COG4948	Mandelate Racemase Muconate Lactonizing
QR90_RS02570	COG4956	integral membrane protein (PIN domain superfamily)
QR90_RS02595	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
QR90_RS02600	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
QR90_RS02600	COG1796	DNA polymerase
QR90_RS02615	COG0237	dephospho-CoA kinase activity
QR90_RS02620	COG0504	CTP synthase activity
QR90_RS02625	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
QR90_RS02635	COG3422	double-strand break repair
QR90_RS02650	COG1960	acyl-CoA dehydrogenase activity
QR90_RS02655	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
QR90_RS02660	COG1960	acyl-CoA dehydrogenase activity
QR90_RS02690	COG0129	dihydroxy-acid dehydratase activity
QR90_RS02700	COG0134	indole-3-glycerol-phosphate synthase activity
QR90_RS02705	COG5002	protein histidine kinase activity
QR90_RS02710	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
QR90_RS02715	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
QR90_RS02720	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
QR90_RS02725	COG0649	NAD binding
QR90_RS02730	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
QR90_RS02735	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
QR90_RS02740	COG1034	ATP synthesis coupled electron transport
QR90_RS02745	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
QR90_RS02750	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
QR90_RS02755	COG0839	Belongs to the complex I subunit 6 family
QR90_RS02760	COG0713	ATP synthesis coupled electron transport
QR90_RS02765	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
QR90_RS02770	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
QR90_RS02775	COG1007	ATP synthesis coupled electron transport
QR90_RS02790	COG0673	inositol 2-dehydrogenase activity
QR90_RS02800	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
QR90_RS02815	COG1193	negative regulation of DNA recombination
QR90_RS02835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
QR90_RS02840	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
QR90_RS02860	COG0395	ABC-type sugar transport system, permease component
QR90_RS02865	COG0482	sulfurtransferase activity
QR90_RS02870	COG0745	RESPONSE REGULATOR receiver
QR90_RS02875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
QR90_RS02890	COG0300	oxidoreductase activity
QR90_RS02905	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
QR90_RS02930	COG0193	aminoacyl-tRNA hydrolase activity
QR90_RS02935	COG1363	Peptidase, m42
QR90_RS02940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
QR90_RS02945	COG2124	cytochrome p450
QR90_RS02960	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
QR90_RS03010	COG0505	Belongs to the CarA family
QR90_RS03030	COG0765	amino acid transport
QR90_RS03035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
QR90_RS03045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
QR90_RS03050	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
QR90_RS03085	COG0635	Involved in the biosynthesis of porphyrin-containing compound
QR90_RS03100	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
QR90_RS03130	COG2807	transmembrane transport
QR90_RS03145	COG4302	ethanolamine ammonia-lyase activity
QR90_RS03160	COG0477	Major facilitator Superfamily
QR90_RS03170	COG3842	ATPase activity
QR90_RS03180	COG1840	ABC-type Fe3 transport system, periplasmic component
QR90_RS03190	COG3290	protein histidine kinase activity
QR90_RS03205	COG1529	Aldehyde oxidase and xanthine dehydrogenase
QR90_RS03210	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
QR90_RS03215	COG2080	2 iron, 2 sulfur cluster binding
QR90_RS03225	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
QR90_RS03235	COG0335	large ribosomal subunit rRNA binding
QR90_RS03250	COG0321	lipoyl(octanoyl) transferase activity
QR90_RS03255	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
QR90_RS03265	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
QR90_RS03270	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
QR90_RS03275	COG0391	Required for morphogenesis under gluconeogenic growth conditions
QR90_RS03280	COG1660	Displays ATPase and GTPase activities
QR90_RS03290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
QR90_RS03290	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
QR90_RS03295	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
QR90_RS03330	COG1304	FMN binding
QR90_RS03340	COG0632	four-way junction helicase activity
QR90_RS03345	COG1309	transcriptional regulator
QR90_RS03350	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
QR90_RS03355	COG3426	butyrate kinase activity
QR90_RS03365	COG0456	acetyltransferase
QR90_RS03375	COG2409	Drug exporters of the RND superfamily
QR90_RS03390	COG0561	phosphatase activity
QR90_RS03395	COG0384	phenazine biosynthesis protein PhzF
QR90_RS03410	COG1126	abc transporter atp-binding protein
QR90_RS03415	COG2358	TRAP transporter, solute receptor (TAXI family
QR90_RS03425	COG0628	permease
QR90_RS03445	COG3265	gluconokinase activity
QR90_RS03455	COG4294	response to UV
QR90_RS03465	COG1404	Belongs to the peptidase S8 family
QR90_RS03480	COG1100	Small GTP-binding protein
QR90_RS03485	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
QR90_RS03490	COG2111	Na H antiporter
QR90_RS03490	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
QR90_RS03495	COG2111	Na H antiporter
QR90_RS03500	COG1006	Multisubunit Na H antiporter MnhC subunit
QR90_RS03505	COG0651	ATP synthesis coupled electron transport
QR90_RS03515	COG2212	antiporter activity
QR90_RS03520	COG1320	monovalent cation:proton antiporter activity
QR90_RS03525	COG0295	cytidine deaminase activity
QR90_RS03530	COG1253	flavin adenine dinucleotide binding
QR90_RS03535	COG0604	alcohol dehydrogenase
QR90_RS03540	COG1404	Belongs to the peptidase S8 family
QR90_RS03555	COG0494	nUDIX hydrolase
QR90_RS03560	COG2318	DinB family
QR90_RS03565	COG1694	Mazg nucleotide pyrophosphohydrolase
QR90_RS03575	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
QR90_RS03580	COG0668	transmembrane transport
QR90_RS03595	COG0018	arginyl-trna synthetase
QR90_RS03610	COG0287	Prephenate dehydrogenase
QR90_RS03615	COG1131	(ABC) transporter
QR90_RS03625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
QR90_RS03630	COG1121	(ABC) transporter
QR90_RS03635	COG0803	Belongs to the bacterial solute-binding protein 9 family
QR90_RS03660	COG1213	nucleotidyl transferase
QR90_RS03660	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
QR90_RS03685	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
QR90_RS03695	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
QR90_RS03700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
QR90_RS03705	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
QR90_RS03715	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
QR90_RS03730	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
QR90_RS03735	COG0517	IMP dehydrogenase activity
QR90_RS03735	COG0516	GMP reductase activity
QR90_RS03740	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
QR90_RS03745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
QR90_RS03755	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
QR90_RS03760	COG2873	o-acetylhomoserine
QR90_RS03775	COG0735	belongs to the Fur family
QR90_RS03790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
QR90_RS03795	COG1562	ergosterol biosynthetic process
QR90_RS03800	COG0737	Belongs to the 5'-nucleotidase family
QR90_RS03810	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
QR90_RS03815	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
QR90_RS03820	COG1435	thymidine kinase activity
QR90_RS03825	COG0254	rRNA binding
QR90_RS03830	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
QR90_RS03865	COG2351	hydroxyisourate hydrolase activity
QR90_RS03880	COG0484	heat shock protein binding
QR90_RS03890	COG2272	Belongs to the type-B carboxylesterase lipase family
QR90_RS03895	COG0673	inositol 2-dehydrogenase activity
QR90_RS03915	COG2255	four-way junction helicase activity
QR90_RS03940	COG0776	regulation of translation
QR90_RS03945	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
QR90_RS03950	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
QR90_RS03960	COG1185	polyribonucleotide nucleotidyltransferase activity
QR90_RS03965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
QR90_RS03975	COG0393	Putative heavy-metal-binding
QR90_RS03980	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
QR90_RS03985	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
QR90_RS03995	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
QR90_RS04005	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
QR90_RS04010	COG1181	Belongs to the D-alanine--D-alanine ligase family
QR90_RS04015	COG2205	protein histidine kinase activity
QR90_RS04020	COG0745	RESPONSE REGULATOR receiver
QR90_RS04040	COG1136	(ABC) transporter
QR90_RS04045	COG1136	(ABC) transporter
QR90_RS04045	COG0577	efflux transmembrane transporter activity
QR90_RS04055	COG4636	protein conserved in cyanobacteria
QR90_RS04075	COG0151	Belongs to the GarS family
QR90_RS04080	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
QR90_RS04090	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
QR90_RS04105	COG0746	molybdenum cofactor guanylyltransferase activity
QR90_RS04115	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
QR90_RS04125	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
QR90_RS04130	COG0812	UDP-N-acetylmuramate dehydrogenase activity
QR90_RS04135	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
QR90_RS04140	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
QR90_RS04155	COG1470	cell adhesion involved in biofilm formation
QR90_RS04155	COG0366	Alpha amylase catalytic
QR90_RS04165	COG2197	response regulator
QR90_RS04175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
QR90_RS04195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
QR90_RS04200	COG0667	Aldo Keto reductase
QR90_RS04220	COG0778	Nitroreductase
QR90_RS04240	COG0542	response to heat
QR90_RS04260	COG0640	Transcriptional regulator
QR90_RS04265	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
QR90_RS04300	COG0542	response to heat
QR90_RS04320	COG2094	Belongs to the DNA glycosylase MPG family
QR90_RS04335	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
QR90_RS04335	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
QR90_RS04375	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
QR90_RS04385	COG0747	negative chemotaxis
QR90_RS04390	COG0601	transmembrane transport
QR90_RS04395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
QR90_RS04405	COG0181	hydroxymethylbilane synthase activity
QR90_RS04440	COG0784	Response regulator, receiver
QR90_RS04445	COG4251	negative regulation of phosphorylation
QR90_RS04460	COG1131	(ABC) transporter
QR90_RS04490	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
QR90_RS04510	COG3655	Transcriptional regulator
QR90_RS04515	COG0561	phosphatase activity
QR90_RS04520	COG0736	holo-[acyl-carrier-protein] synthase activity
QR90_RS04555	COG1744	ABC transporter substrate-binding protein PnrA-like
QR90_RS04560	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
QR90_RS04570	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
QR90_RS04575	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
QR90_RS04580	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
QR90_RS04590	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
QR90_RS04595	COG0174	glutamine synthetase
QR90_RS04630	COG2364	Membrane
QR90_RS04640	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
QR90_RS04645	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
QR90_RS04670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
QR90_RS04675	COG0247	lactate metabolic process
QR90_RS04680	COG0277	FAD linked oxidase domain protein
QR90_RS04695	COG0737	Belongs to the 5'-nucleotidase family
QR90_RS04700	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
QR90_RS04730	COG1960	acyl-CoA dehydrogenase activity
QR90_RS04740	COG0515	serine threonine protein kinase
QR90_RS04740	COG2815	serine threonine protein kinase
QR90_RS04745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
QR90_RS04750	COG0492	ferredoxin-NADP+ reductase activity
QR90_RS04760	COG0387	Pfam Sodium calcium exchanger
QR90_RS04765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
QR90_RS04770	COG0537	adenosine 5'-monophosphoramidase activity
QR90_RS04790	COG1968	undecaprenyl-diphosphatase activity
QR90_RS04800	COG1309	transcriptional regulator
QR90_RS04805	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
QR90_RS04830	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
QR90_RS04935	COG4948	Mandelate Racemase Muconate Lactonizing
QR90_RS04945	COG0601	transmembrane transport
QR90_RS04950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
QR90_RS04955	COG0747	negative chemotaxis
QR90_RS04965	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
QR90_RS04970	COG1737	Transcriptional regulator
QR90_RS04975	COG0243	molybdopterin cofactor binding
QR90_RS04980	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
QR90_RS04985	COG0251	oxidation-reduction process
QR90_RS04995	COG1846	Transcriptional regulator
QR90_RS05000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
QR90_RS05010	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
QR90_RS05015	COG2967	ApaG domain
QR90_RS05020	COG1363	Peptidase, m42
QR90_RS05030	COG1205	dead DEAH box helicase
QR90_RS05030	COG1111	helicase
QR90_RS05035	COG0514	ATP-dependent DNA helicase (RecQ)
QR90_RS05070	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
QR90_RS05115	COG1459	type II secretion system
QR90_RS05120	COG0009	L-threonylcarbamoyladenylate synthase
QR90_RS05125	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
QR90_RS05140	COG0791	NLP P60 protein
QR90_RS05150	COG3273	potassium ion transport
QR90_RS05150	COG0471	metal ion transport
QR90_RS05155	COG0066	3-isopropylmalate dehydratase activity
QR90_RS05160	COG0473	3-isopropylmalate dehydrogenase activity
QR90_RS05165	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
QR90_RS05170	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
QR90_RS05190	COG0183	Belongs to the thiolase family
QR90_RS05200	COG1250	3-hydroxyacyl-CoA dehydrogenase
QR90_RS05200	COG1024	Enoyl-CoA hydratase
QR90_RS05205	COG3173	Aminoglycoside phosphotransferase
QR90_RS05215	COG0822	iron-sulfur transferase activity
QR90_RS05220	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
QR90_RS05225	COG0446	pyridine nucleotide-disulphide oxidoreductase
QR90_RS05230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
QR90_RS05235	COG2814	Major facilitator Superfamily
QR90_RS05245	COG0525	valine-tRNA ligase activity
QR90_RS05250	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
QR90_RS05260	COG2072	flavoprotein involved in K transport
QR90_RS05270	COG1660	Displays ATPase and GTPase activities
QR90_RS05285	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
QR90_RS05305	COG2819	hydrolase of the alpha beta superfamily
QR90_RS05310	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
QR90_RS05320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
QR90_RS05325	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
QR90_RS05330	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
QR90_RS05335	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
QR90_RS05340	COG1450	Type ii and iii secretion system protein
QR90_RS05375	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
QR90_RS05385	COG1461	Dihydroxyacetone kinase
QR90_RS05395	COG0477	Major facilitator Superfamily
QR90_RS05405	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
QR90_RS05420	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
QR90_RS05425	COG0049	tRNA binding
QR90_RS05430	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
QR90_RS05445	COG0051	transcription antitermination factor activity, RNA binding
QR90_RS05450	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
QR90_RS05455	COG0088	Forms part of the polypeptide exit tunnel
QR90_RS05460	COG0089	rRNA binding
QR90_RS05465	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
QR90_RS05470	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
QR90_RS05475	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
QR90_RS05480	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
QR90_RS05485	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
QR90_RS05490	COG0255	Belongs to the universal ribosomal protein uL29 family
QR90_RS05495	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
QR90_RS05500	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
QR90_RS05505	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
QR90_RS05510	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
QR90_RS05515	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
QR90_RS05520	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
QR90_RS05525	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
QR90_RS05530	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
QR90_RS05535	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
QR90_RS05540	COG1841	ribosomal large subunit assembly
QR90_RS05545	COG0200	Binds to the 23S rRNA
QR90_RS05550	COG0201	protein transport
QR90_RS05555	COG0563	adenylate kinase activity
QR90_RS05570	COG0714	Associated with various cellular activities
QR90_RS05580	COG3552	Protein containing von Willebrand factor type A (VWA) domain
QR90_RS05585	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
QR90_RS05590	COG0257	Belongs to the bacterial ribosomal protein bL36 family
QR90_RS05595	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
QR90_RS05600	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
QR90_RS05605	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
QR90_RS05610	COG0202	RNA polymerase activity
QR90_RS05615	COG0203	ribosomal protein L17
QR90_RS05635	COG0363	glucosamine-6-phosphate deaminase activity
QR90_RS05640	COG1486	melibiose metabolic process
QR90_RS05645	COG4608	Belongs to the ABC transporter superfamily
QR90_RS05650	COG0444	Belongs to the ABC transporter superfamily
QR90_RS05655	COG0601	transmembrane transport
QR90_RS05665	COG1609	Transcriptional regulator
QR90_RS05680	COG0328	RNA-DNA hybrid ribonuclease activity
QR90_RS05695	COG0824	Thioesterase
QR90_RS05700	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
QR90_RS05705	COG3942	CHAP domain
QR90_RS05705	COG1388	LysM domain
QR90_RS05730	COG1774	PSP1 C-terminal conserved region
QR90_RS05735	COG0251	oxidation-reduction process
QR90_RS05740	COG0631	protein serine/threonine phosphatase activity
QR90_RS05745	COG0154	amidase activity
QR90_RS05750	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
QR90_RS05760	COG1187	pseudouridine synthase activity
QR90_RS05765	COG1760	l-serine dehydratase
QR90_RS05785	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
QR90_RS05790	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
QR90_RS05820	COG3118	belongs to the thioredoxin family
QR90_RS05835	COG0416	fatty acid biosynthetic process
QR90_RS05840	COG2308	Evidence 4 Homologs of previously reported genes of
QR90_RS05850	COG1305	Transglutaminase-like
QR90_RS05860	COG0300	oxidoreductase activity
QR90_RS05865	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
QR90_RS05880	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
QR90_RS05885	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
QR90_RS05890	COG1546	Belongs to the CinA family
QR90_RS05890	COG1058	Belongs to the CinA family
QR90_RS05915	COG2197	response regulator
QR90_RS05925	COG2608	mercury ion transmembrane transporter activity
QR90_RS05935	COG0488	(ABC) transporter
QR90_RS05965	COG1252	NADH dehydrogenase
QR90_RS05970	COG5322	oxidoreductase activity
QR90_RS05980	COG2329	Antibiotic biosynthesis monooxygenase
QR90_RS05985	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
QR90_RS05995	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
QR90_RS06010	COG1573	uracil-dna glycosylase
QR90_RS06020	COG1490	D-aminoacyl-tRNA deacylase activity
QR90_RS06025	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
QR90_RS06040	COG0738	Major facilitator superfamily
QR90_RS06045	COG1609	Transcriptional regulator
QR90_RS06060	COG1522	sequence-specific DNA binding
QR90_RS06070	COG0523	cobalamin synthesis protein
QR90_RS06080	COG2050	protein possibly involved in aromatic compounds catabolism
QR90_RS06085	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
QR90_RS06090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
QR90_RS06105	COG0750	zinc metalloprotease
QR90_RS06110	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
QR90_RS06115	COG1028	Short-chain dehydrogenase reductase Sdr
QR90_RS06120	COG0626	cystathionine gamma-synthase activity
QR90_RS06130	COG0473	3-isopropylmalate dehydrogenase activity
QR90_RS06135	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
QR90_RS06135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
QR90_RS06140	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
QR90_RS06140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
QR90_RS06145	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
QR90_RS06150	COG0318	PFAM AMP-dependent synthetase and ligase
QR90_RS06160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
QR90_RS06180	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
QR90_RS06190	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
QR90_RS06200	COG3842	ATPase activity
QR90_RS06210	COG1131	(ABC) transporter
QR90_RS06220	COG1217	gtp-binding protein TYPA
QR90_RS06255	COG2843	Capsule synthesis protein
QR90_RS06275	COG0747	negative chemotaxis
QR90_RS06280	COG0601	transmembrane transport
QR90_RS06285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
QR90_RS06305	COG0735	belongs to the Fur family
QR90_RS06310	COG0753	catalase activity
QR90_RS06330	COG0681	Belongs to the peptidase S26 family
QR90_RS06340	COG2815	serine threonine protein kinase
QR90_RS06340	COG0515	serine threonine protein kinase
QR90_RS06345	COG0366	Alpha amylase catalytic
QR90_RS06355	COG1316	TRANSCRIPTIONal
QR90_RS06370	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
QR90_RS06375	COG1131	(ABC) transporter
QR90_RS06405	COG1902	pentaerythritol trinitrate reductase activity
QR90_RS06410	COG1136	(ABC) transporter
QR90_RS06420	COG0179	Fumarylacetoacetate (FAA) hydrolase
QR90_RS06430	COG1185	polyribonucleotide nucleotidyltransferase activity
QR90_RS06435	COG0765	amino acid transport
QR90_RS06445	COG1960	acyl-CoA dehydrogenase activity
QR90_RS06460	COG0494	nUDIX hydrolase
QR90_RS06470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
QR90_RS06505	COG4555	ABC transporter
QR90_RS06515	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
QR90_RS06520	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
QR90_RS06525	COG2094	Belongs to the DNA glycosylase MPG family
QR90_RS06530	COG0442	prolyl-tRNA aminoacylation
QR90_RS06555	COG1131	(ABC) transporter
QR90_RS06560	COG0842	Transport permease protein
QR90_RS06570	COG4585	Histidine kinase
QR90_RS06575	COG2197	response regulator
QR90_RS06820	COG5499	transcription regulator containing HTH domain
QR90_RS06900	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
QR90_RS06915	COG1695	Transcriptional regulator
QR90_RS06925	COG0741	lytic transglycosylase activity
QR90_RS06925	COG0739	heme binding
QR90_RS06925	COG1196	nuclear chromosome segregation
QR90_RS06930	COG0101	tRNA pseudouridine synthase activity
QR90_RS06945	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
QR90_RS06950	COG1678	Uncharacterized ACR, COG1678
QR90_RS06955	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
QR90_RS06965	COG0702	epimerase
QR90_RS06975	COG0318	PFAM AMP-dependent synthetase and ligase
QR90_RS06985	COG1022	Amp-dependent synthetase and ligase
QR90_RS07030	COG0714	Associated with various cellular activities
QR90_RS07065	COG1653	transport
QR90_RS07070	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
QR90_RS07075	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
QR90_RS07090	COG1864	DNA RNA non-specific endonuclease
QR90_RS07090	COG3591	Belongs to the peptidase S1B family
QR90_RS07105	COG2814	Major facilitator Superfamily
QR90_RS07115	COG1175	transmembrane transport
QR90_RS07120	COG3833	ABC-type maltose transport systems, permease component
QR90_RS07125	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
QR90_RS07135	COG0497	DNA recombination
QR90_RS07150	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
QR90_RS07160	COG0521	Mo-molybdopterin cofactor biosynthetic process
QR90_RS07170	COG0585	pseudouridine synthase activity
QR90_RS07190	COG3457	Alanine racemase
QR90_RS07195	COG3973	AAA domain
QR90_RS07210	COG0033	Phosphoglucomutase
QR90_RS07220	COG0728	peptidoglycan biosynthetic process
QR90_RS07230	COG1754	DNA topoisomerase type I activity
QR90_RS07230	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
QR90_RS07250	COG0220	tRNA (guanine-N7-)-methyltransferase activity
QR90_RS07260	COG0475	glutathione-regulated potassium exporter activity
QR90_RS07280	COG1028	Short-chain dehydrogenase reductase Sdr
QR90_RS07310	COG0596	Alpha beta hydrolase
QR90_RS07360	COG1054	Belongs to the UPF0176 family
QR90_RS07365	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
QR90_RS07380	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
QR90_RS07385	COG1132	(ABC) transporter
QR90_RS07400	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
QR90_RS07410	COG2124	cytochrome p450
QR90_RS07415	COG3001	Fructosamine kinase
QR90_RS07460	COG2045	Belongs to the ComB family
QR90_RS07465	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
QR90_RS07470	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
QR90_RS07480	COG0402	S-adenosylhomocysteine deaminase activity
QR90_RS07485	COG4269	membrane
QR90_RS07495	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
QR90_RS07500	COG0564	pseudouridine synthase activity
QR90_RS07510	COG1918	ferrous iron import across plasma membrane
QR90_RS07510	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
QR90_RS07530	COG1959	2 iron, 2 sulfur cluster binding
QR90_RS07535	COG0167	dihydroorotate dehydrogenase activity
QR90_RS07545	COG4585	Histidine kinase
QR90_RS07550	COG0552	protein localization to endoplasmic reticulum
QR90_RS07555	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
QR90_RS07570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
QR90_RS07575	COG0756	dUTP diphosphatase activity
QR90_RS07600	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
QR90_RS07615	COG0318	PFAM AMP-dependent synthetase and ligase
QR90_RS07620	COG4221	oxidoreductase activity
QR90_RS07625	COG1605	Chorismate mutase
QR90_RS07625	COG0077	Prephenate dehydratase
QR90_RS07630	COG0154	amidase activity
QR90_RS07635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
QR90_RS07655	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
QR90_RS07665	COG0489	protein tyrosine kinase activity
QR90_RS07680	COG0667	Aldo Keto reductase
QR90_RS07695	COG0783	Belongs to the Dps family
QR90_RS07705	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
QR90_RS07730	COG1104	cysteine desulfurase activity
QR90_RS07735	COG0515	serine threonine protein kinase
QR90_RS07735	COG2815	serine threonine protein kinase
QR90_RS07750	COG1842	Phage shock protein A
QR90_RS07760	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
QR90_RS07765	COG0194	GDP metabolic process
QR90_RS07785	COG0640	Transcriptional regulator
QR90_RS07800	COG2217	Heavy metal translocating P-type atpase
QR90_RS07810	COG0066	3-isopropylmalate dehydratase activity
QR90_RS07825	COG0189	ligase activity
QR90_RS07835	COG0149	triose-phosphate isomerase activity
QR90_RS07840	COG0126	phosphoglycerate kinase activity
QR90_RS07855	COG1472	Belongs to the glycosyl hydrolase 3 family
QR90_RS07860	COG3507	Belongs to the glycosyl hydrolase 43 family
QR90_RS07875	COG0395	ABC-type sugar transport system, permease component
QR90_RS07880	COG1175	transmembrane transport
QR90_RS07890	COG1609	Transcriptional regulator
QR90_RS07905	COG1028	Short-chain dehydrogenase reductase Sdr
QR90_RS07910	COG0322	excinuclease ABC activity
QR90_RS07920	COG0406	alpha-ribazole phosphatase activity
QR90_RS07925	COG0438	transferase activity, transferring glycosyl groups
QR90_RS07935	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
QR90_RS07945	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
QR90_RS07950	COG0739	heme binding
QR90_RS07955	COG0745	RESPONSE REGULATOR receiver
QR90_RS07960	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
QR90_RS07965	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
QR90_RS07980	COG0791	NLP P60 protein
QR90_RS07995	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
QR90_RS08010	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
QR90_RS08020	COG1803	Methylglyoxal synthase
QR90_RS08020	COG1597	lipid kinase activity
QR90_RS08030	COG0124	histidyl-tRNA synthetase
QR90_RS08035	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
QR90_RS08070	COG0045	succinate-CoA ligase (ADP-forming) activity
QR90_RS08075	COG0006	proline dipeptidase activity
QR90_RS08080	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
QR90_RS08095	COG0183	Belongs to the thiolase family
QR90_RS08110	COG1295	ribonuclease BN
QR90_RS08120	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
QR90_RS08125	COG0438	transferase activity, transferring glycosyl groups
QR90_RS08130	COG0017	Asparaginyl-tRNA synthetase
QR90_RS08140	COG1597	lipid kinase activity
QR90_RS08145	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
QR90_RS08155	COG1643	Atp-dependent helicase
QR90_RS08160	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
QR90_RS08165	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
QR90_RS08165	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
QR90_RS08195	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
QR90_RS08200	COG1017	nitric oxide dioxygenase activity
QR90_RS08200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
QR90_RS08205	COG1959	2 iron, 2 sulfur cluster binding
QR90_RS08210	COG4221	oxidoreductase activity
QR90_RS08225	COG3956	TIGRFAM MazG family protein
QR90_RS08230	COG1051	belongs to the nudix hydrolase family
QR90_RS08240	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
QR90_RS08255	COG3383	formate dehydrogenase (NAD+) activity
QR90_RS08265	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
QR90_RS08400	COG0515	serine threonine protein kinase
QR90_RS08400	COG2815	serine threonine protein kinase
QR90_RS08450	COG0277	FAD linked oxidase domain protein
QR90_RS08460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
QR90_RS08465	COG0601	transmembrane transport
QR90_RS08500	COG1012	belongs to the aldehyde dehydrogenase family
QR90_RS08505	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
QR90_RS08545	COG1205	dead DEAH box helicase
QR90_RS08545	COG1111	helicase
QR90_RS08560	COG1074	ATP-dependent DNA helicase activity
QR90_RS08585	COG1111	helicase
QR90_RS08585	COG1205	dead DEAH box helicase
QR90_RS08590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
QR90_RS08695	COG1111	helicase
QR90_RS08695	COG1205	dead DEAH box helicase
QR90_RS08790	COG4948	Mandelate Racemase Muconate Lactonizing
QR90_RS08800	COG1312	Catalyzes the dehydration of D-mannonate
QR90_RS08810	COG0800	Aldolase
QR90_RS08815	COG1070	Carbohydrate kinase
QR90_RS08820	COG0395	ABC-type sugar transport system, permease component
QR90_RS08835	COG2226	methyltransferase
QR90_RS08850	COG4712	double-strand break repair protein
QR90_RS08865	COG0747	negative chemotaxis
QR90_RS08870	COG0318	PFAM AMP-dependent synthetase and ligase
QR90_RS08885	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
QR90_RS08905	COG0747	negative chemotaxis
QR90_RS08910	COG0601	transmembrane transport
QR90_RS08920	COG0444	Belongs to the ABC transporter superfamily
QR90_RS08925	COG4608	Belongs to the ABC transporter superfamily
QR90_RS08975	COG1494	fructose-1,6-bisphosphatase
QR90_RS08980	COG1959	2 iron, 2 sulfur cluster binding
QR90_RS08990	COG0672	)-iron permease
QR90_RS09005	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
QR90_RS09010	COG0477	Major facilitator Superfamily
QR90_RS09020	COG0655	NAD(P)H dehydrogenase (quinone) activity
QR90_RS09025	COG0534	Mate efflux family protein
QR90_RS09030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
QR90_RS09045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
QR90_RS09050	COG3012	SEC-C Motif Domain Protein
QR90_RS09055	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
QR90_RS09060	COG0519	Catalyzes the synthesis of GMP from XMP
QR90_RS09060	COG0518	GMP synthase (glutamine-hydrolyzing) activity
QR90_RS09090	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
QR90_RS09105	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
QR90_RS09110	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
QR90_RS09130	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
QR90_RS09135	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
QR90_RS09140	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
QR90_RS09150	COG0363	glucosamine-6-phosphate deaminase activity
QR90_RS09160	COG0012	GTP binding
QR90_RS09185	COG0575	Belongs to the CDS family
QR90_RS09190	COG0233	cytoplasmic translational termination
QR90_RS09195	COG0528	UMP kinase activity
QR90_RS09200	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
QR90_RS09205	COG0052	Belongs to the universal ribosomal protein uS2 family
QR90_RS09215	COG1247	-acetyltransferase
QR90_RS09230	COG1307	EDD domain protein, DegV family
QR90_RS09235	COG1472	Belongs to the glycosyl hydrolase 3 family
QR90_RS09240	COG1653	transport
QR90_RS09250	COG0747	negative chemotaxis
QR90_RS09255	COG0601	transmembrane transport
QR90_RS09260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
QR90_RS09280	COG1250	3-hydroxyacyl-CoA dehydrogenase
QR90_RS09315	COG1692	metallophosphoesterase
QR90_RS09320	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
QR90_RS09325	COG0019	diaminopimelate decarboxylase activity
QR90_RS09330	COG0037	tRNA processing
QR90_RS09330	COG0590	tRNA wobble adenosine to inosine editing
QR90_RS09335	COG0494	nUDIX hydrolase
QR90_RS09340	COG0196	riboflavin kinase activity
QR90_RS09350	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
QR90_RS09360	COG2032	superoxide dismutase activity
QR90_RS09365	COG1131	(ABC) transporter
QR90_RS09380	COG1605	Chorismate mutase
QR90_RS09380	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
QR90_RS09395	COG2986	histidine ammonia-lyase
QR90_RS09400	COG1228	amidohydrolase
QR90_RS09410	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
QR90_RS09420	COG1760	l-serine dehydratase
QR90_RS09425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
QR90_RS09455	COG0297	glycogen (starch) synthase activity
QR90_RS09460	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
QR90_RS09465	COG3845	ABC transporter
QR90_RS09495	COG5412	phage tail tape measure protein
QR90_RS09505	COG0656	L-ascorbic acid biosynthetic process
QR90_RS09510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
QR90_RS09515	COG0242	peptide deformylase activity
QR90_RS09540	COG0745	RESPONSE REGULATOR receiver
QR90_RS09565	COG0494	nUDIX hydrolase
QR90_RS09570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
QR90_RS09570	COG0072	phenylalanine-tRNA ligase activity
QR90_RS09590	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
QR90_RS09595	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
QR90_RS09605	COG1011	Hydrolase
QR90_RS09610	COG0492	ferredoxin-NADP+ reductase activity
QR90_RS09615	COG4221	oxidoreductase activity
QR90_RS09630	COG0860	N-Acetylmuramoyl-L-alanine amidase
QR90_RS09630	COG2247	cell wall binding repeat
QR90_RS09640	COG0513	Belongs to the DEAD box helicase family
QR90_RS09645	COG0028	Belongs to the TPP enzyme family
QR90_RS09655	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
QR90_RS09670	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
QR90_RS09705	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
QR90_RS09710	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
QR90_RS09725	COG2337	Toxic component of a toxin-antitoxin (TA) module
QR90_RS09730	COG0183	Belongs to the thiolase family
QR90_RS09735	COG1598	PFAM Uncharacterised protein family UPF0150
QR90_RS09740	COG1024	Enoyl-CoA hydratase
QR90_RS09740	COG1250	3-hydroxyacyl-CoA dehydrogenase
QR90_RS09750	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
QR90_RS09755	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
QR90_RS09760	COG0163	prenyltransferase activity
QR90_RS09770	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
QR90_RS09795	COG0165	Argininosuccinate lyase
QR90_RS09810	COG1175	transmembrane transport
QR90_RS09815	COG0395	ABC-type sugar transport system, permease component
QR90_RS09820	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
QR90_RS09835	COG0793	Belongs to the peptidase S41A family
QR90_RS09835	COG4946	Tricorn protease homolog
QR90_RS09865	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
QR90_RS09875	COG0390	transport system, permease component
QR90_RS09880	COG3842	ATPase activity
QR90_RS09910	COG0671	phosphoesterase, PA-phosphatase related
QR90_RS09965	COG2009	succinate dehydrogenase
QR90_RS09975	COG1053	succinate dehydrogenase
QR90_RS09980	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
QR90_RS10005	COG0113	porphobilinogen synthase activity
QR90_RS10025	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
QR90_RS10030	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
QR90_RS10035	COG0704	Plays a role in the regulation of phosphate uptake
QR90_RS10045	COG1254	Belongs to the acylphosphatase family
QR90_RS10065	COG0788	formyltetrahydrofolate deformylase activity
QR90_RS10110	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
QR90_RS10115	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
QR90_RS10130	COG1090	epimerase
QR90_RS10165	COG1252	NADH dehydrogenase
QR90_RS10185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
QR90_RS10205	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
QR90_RS10210	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
QR90_RS10215	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
QR90_RS10220	COG0131	Imidazoleglycerol-phosphate dehydratase
QR90_RS10225	COG4712	double-strand break repair protein
QR90_RS10235	COG1307	EDD domain protein, DegV family
QR90_RS10240	COG0247	lactate metabolic process
QR90_RS10240	COG2181	nitrate reductase activity
QR90_RS10255	COG2816	NAD+ diphosphatase activity
QR90_RS10295	COG0667	Aldo Keto reductase
QR90_RS10300	COG0210	DNA helicase
QR90_RS10305	COG3870	Protein conserved in bacteria
QR90_RS10315	COG1914	H( )-stimulated, divalent metal cation uptake system
QR90_RS10320	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
QR90_RS10320	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
QR90_RS10360	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
QR90_RS10385	COG0495	leucyl-tRNA aminoacylation
QR90_RS10405	COG4989	oxidoreductase activity
QR90_RS10415	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
QR90_RS10415	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
QR90_RS10435	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
QR90_RS10440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
QR90_RS10480	COG0366	Alpha amylase catalytic
QR90_RS10495	COG2151	metal-sulfur cluster biosynthetic enzyme
QR90_RS10500	COG3396	Phenylacetate-CoA oxygenase
QR90_RS10510	COG3396	Phenylacetate-CoA oxygenase
QR90_RS10515	COG0142	geranyltranstransferase activity
QR90_RS10525	COG1668	transmembrane transport
QR90_RS10555	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
QR90_RS10580	COG0488	(ABC) transporter
QR90_RS10590	COG2814	Major facilitator Superfamily
QR90_RS10610	COG0333	Belongs to the bacterial ribosomal protein bL32 family
QR90_RS10640	COG3191	aminopeptidase activity
QR90_RS10645	COG1164	Oligoendopeptidase f
QR90_RS10665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
QR90_RS10675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
QR90_RS10685	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
QR90_RS10690	COG0232	Belongs to the dGTPase family. Type 2 subfamily
QR90_RS10695	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
QR90_RS10700	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
QR90_RS10710	COG0330	HflC and HflK could
QR90_RS10715	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
QR90_RS10730	COG0737	Belongs to the 5'-nucleotidase family
QR90_RS10730	COG1525	nuclease
QR90_RS10730	COG4085	toxin activity
QR90_RS10740	COG1047	Peptidyl-prolyl cis-trans
QR90_RS10745	COG0017	Asparaginyl-tRNA synthetase
QR90_RS10760	COG0826	peptidase U32
QR90_RS10780	COG2030	dehydratase
QR90_RS10785	COG2301	Belongs to the HpcH HpaI aldolase family
QR90_RS10795	COG1131	(ABC) transporter
QR90_RS10800	COG0850	regulation of cytokinetic process
QR90_RS10805	COG0779	Required for maturation of 30S ribosomal subunits
QR90_RS10810	COG0195	Participates in both transcription termination and antitermination
QR90_RS10820	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
QR90_RS10830	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
QR90_RS10830	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
QR90_RS10835	COG0667	Aldo Keto reductase
QR90_RS10850	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
QR90_RS10865	COG0793	Belongs to the peptidase S41A family
QR90_RS10880	COG1309	transcriptional regulator
QR90_RS10885	COG0539	negative regulation of cytoplasmic translation
QR90_RS10900	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
QR90_RS10905	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
QR90_RS10910	COG0142	geranyltranstransferase activity
QR90_RS10945	COG0670	Belongs to the BI1 family
QR90_RS10970	COG1381	Involved in DNA repair and RecF pathway recombination
QR90_RS10980	COG1385	rRNA (uridine-N3-)-methyltransferase activity
QR90_RS10985	COG2264	protein methyltransferase activity
QR90_RS10990	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
QR90_RS11005	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
QR90_RS11015	COG4106	trans-aconitate 2-methyltransferase activity
QR90_RS11020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
QR90_RS11055	COG0616	signal peptide processing
QR90_RS11070	COG2201	protein-glutamate methylesterase activity
QR90_RS11075	COG3290	protein histidine kinase activity
QR90_RS11105	COG0037	tRNA processing
QR90_RS11120	COG1231	oxidoreductase activity
QR90_RS11130	COG0354	folic acid binding
QR90_RS11135	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
QR90_RS11140	COG1648	precorrin-2 dehydrogenase activity
QR90_RS11140	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
QR90_RS11170	COG0739	heme binding
QR90_RS11180	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
QR90_RS11185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
QR90_RS11190	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
QR90_RS11205	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
QR90_RS11205	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
QR90_RS11220	COG2720	vancomycin resistance protein
QR90_RS11225	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
QR90_RS11245	COG2096	Adenosyltransferase
QR90_RS11250	COG0303	'Molybdopterin
QR90_RS11260	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
QR90_RS11265	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
QR90_RS11275	COG0730	response to heat
QR90_RS11285	COG0346	lactoylglutathione lyase activity
QR90_RS11295	COG2217	Heavy metal translocating P-type atpase
QR90_RS11315	COG3424	synthase
QR90_RS11320	COG0667	Aldo Keto reductase
QR90_RS11325	COG0778	Nitroreductase
QR90_RS11345	COG3361	conserved protein (COG2071)
QR90_RS11355	COG2124	cytochrome p450
QR90_RS11360	COG0456	acetyltransferase
QR90_RS11375	COG1166	arginine decarboxylase activity
QR90_RS11390	COG1408	metallophosphoesterase
QR90_RS11395	COG0825	malonyl-CoA metabolic process
QR90_RS11400	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
QR90_RS11410	COG1324	tolerance protein
QR90_RS11420	COG2199	diguanylate cyclase activity
QR90_RS11430	COG0628	permease
QR90_RS11455	COG1764	response to oxidative stress
QR90_RS11475	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
QR90_RS11490	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
QR90_RS11505	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
QR90_RS11510	COG0205	6-phosphofructokinase activity
QR90_RS11520	COG1285	pathogenesis
QR90_RS11525	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
QR90_RS11530	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
QR90_RS11540	COG0820	rRNA (adenine-C2-)-methyltransferase activity
QR90_RS11560	COG0538	isocitrate dehydrogenase activity
QR90_RS11570	COG1175	transmembrane transport
QR90_RS11575	COG0395	ABC-type sugar transport system, permease component
QR90_RS11585	COG0445	tRNA wobble uridine modification
QR90_RS11610	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
QR90_RS11610	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
QR90_RS11615	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
QR90_RS11630	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
QR90_RS11645	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
QR90_RS11670	COG1012	belongs to the aldehyde dehydrogenase family
QR90_RS11695	COG0159	tryptophan synthase activity
QR90_RS11700	COG0133	tryptophan synthase activity
QR90_RS11705	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
QR90_RS11710	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
QR90_RS11725	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
QR90_RS11730	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
QR90_RS11740	COG1012	belongs to the aldehyde dehydrogenase family
QR90_RS11750	COG0506	proline dehydrogenase activity
QR90_RS11765	COG2354	Protein conserved in bacteria
QR90_RS11775	COG1764	response to oxidative stress
QR90_RS11800	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
QR90_RS11845	COG1132	(ABC) transporter
QR90_RS11855	COG0252	asparaginase activity
QR90_RS11860	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
QR90_RS11865	COG0302	gtp cyclohydrolase
QR90_RS11875	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
QR90_RS11880	COG0084	hydrolase, TatD family'
QR90_RS11900	COG0039	L-malate dehydrogenase activity
QR90_RS11910	COG0617	tRNA 3'-terminal CCA addition
QR90_RS11930	COG1755	Isoprenylcysteine carboxyl methyltransferase
QR90_RS11940	COG0406	alpha-ribazole phosphatase activity
QR90_RS11945	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
QR90_RS11955	COG0138	bifunctional purine biosynthesis protein purh
QR90_RS11960	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
QR90_RS11975	COG1408	metallophosphoesterase
QR90_RS12000	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
QR90_RS12025	COG2321	neutral zinc metallopeptidase
QR90_RS12030	COG3842	ATPase activity
QR90_RS12065	COG2823	Periplasmic or secreted lipoprotein
QR90_RS12065	COG1652	LysM domain
QR90_RS12080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
QR90_RS12085	COG2151	metal-sulfur cluster biosynthetic enzyme
QR90_RS12090	COG2738	Putative neutral zinc metallopeptidase
QR90_RS12095	COG2359	stage V sporulation protein S
QR90_RS12110	COG0024	Methionine aminopeptidase
QR90_RS12115	COG2362	D-Aminopeptidase
QR90_RS12125	COG0123	including yeast histone deacetylase and acetoin utilization protein
QR90_RS12150	COG2197	response regulator
QR90_RS12155	COG0667	Aldo Keto reductase
QR90_RS12175	COG2137	regulation of response to DNA damage stimulus
QR90_RS12180	COG0268	Binds directly to 16S ribosomal RNA
QR90_RS12190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
QR90_RS12200	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
QR90_RS12205	COG1378	Sugar-specific transcriptional regulator TrmB
QR90_RS12220	COG4251	negative regulation of phosphorylation
QR90_RS12235	COG0714	Associated with various cellular activities
QR90_RS12265	COG0481	GTPase activity
QR90_RS12290	COG0653	protein targeting
QR90_RS12295	COG0259	pyridoxamine-phosphate oxidase activity
QR90_RS12300	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
QR90_RS12310	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
QR90_RS12315	COG0180	Tryptophanyl-tRNA synthetase
QR90_RS12320	COG1063	alcohol dehydrogenase
QR90_RS12330	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
QR90_RS12335	COG1028	Short-chain dehydrogenase reductase Sdr
QR90_RS12340	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
QR90_RS12345	COG0805	protein transport
QR90_RS12350	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
QR90_RS12365	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
QR90_RS12375	COG4591	ABC-type transport system involved in lipoprotein release permease component
QR90_RS12395	COG0275	rRNA processing
QR90_RS12400	COG2001	Belongs to the MraZ family
QR90_RS12405	COG2363	Small membrane protein
QR90_RS12425	COG1999	signal sequence binding
QR90_RS12430	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
QR90_RS12430	COG1845	cytochrome c oxidase, subunit III
QR90_RS12435	COG1565	acr, cog1565
QR90_RS12435	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
QR90_RS12440	COG0109	protoheme IX farnesyltransferase activity
QR90_RS12445	COG0109	protoheme IX farnesyltransferase activity
QR90_RS12445	COG1612	heme a metabolic process
QR90_RS12450	COG2322	membrane
QR90_RS12465	COG0215	cysteine-tRNA ligase activity
QR90_RS12470	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
QR90_RS12475	COG0765	amino acid transport
QR90_RS12480	COG0789	Transcriptional regulator
QR90_RS12490	COG0366	Alpha amylase catalytic
QR90_RS12490	COG1874	Beta-galactosidase
QR90_RS12500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
QR90_RS12515	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
QR90_RS12515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
QR90_RS12520	COG3938	Belongs to the proline racemase family
QR90_RS12530	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
QR90_RS12535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
QR90_RS12535	COG0574	Belongs to the PEP-utilizing enzyme family
QR90_RS12545	COG0285	dihydrofolate synthase activity
QR90_RS12550	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
QR90_RS12565	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
QR90_RS12600	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
QR90_RS12630	COG0659	secondary active sulfate transmembrane transporter activity
QR90_RS12645	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
QR90_RS12680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
QR90_RS12725	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
QR90_RS12735	COG4974	Belongs to the 'phage' integrase family
QR90_RS12815	COG0423	glycine-tRNA ligase activity
QR90_RS12835	COG0277	FAD linked oxidase domain protein
QR90_RS12840	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
QR90_RS12845	COG2154	pterin-4-alpha-carbinolamine dehydratase
QR90_RS12865	COG0187	DNA topoisomerase II activity
QR90_RS12875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
QR90_RS12890	COG4585	Histidine kinase
QR90_RS12890	COG2203	Gaf domain
QR90_RS12900	COG2197	response regulator
QR90_RS12905	COG3253	May function as heme-dependent peroxidase
QR90_RS12910	COG0667	Aldo Keto reductase
QR90_RS12925	COG0346	lactoylglutathione lyase activity
QR90_RS12935	COG0105	UTP biosynthetic process
QR90_RS12940	COG4603	Belongs to the binding-protein-dependent transport system permease family
QR90_RS12945	COG1079	Belongs to the binding-protein-dependent transport system permease family
QR90_RS12955	COG0358	DNA primase activity
QR90_RS12965	COG0372	Belongs to the citrate synthase family
QR90_RS12970	COG1214	PFAM Peptidase M22, glycoprotease
QR90_RS12970	COG0456	acetyltransferase
QR90_RS13005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
QR90_RS13015	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
QR90_RS13020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
QR90_RS13035	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
QR90_RS13050	COG0719	Fe-S assembly protein
QR90_RS13060	COG0719	Fe-S assembly protein
QR90_RS13065	COG0396	ATPase activity
QR90_RS13070	COG0811	peptide transport
QR90_RS13075	COG0848	biopolymer transport protein
QR90_RS13095	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
QR90_RS13110	COG0583	DNA-binding transcription factor activity
QR90_RS13115	COG0306	phosphate transporter
QR90_RS13150	COG0489	protein tyrosine kinase activity
QR90_RS13175	COG0642	Histidine kinase
QR90_RS13195	COG0261	This protein binds to 23S rRNA in the presence of protein L20
QR90_RS13200	COG0211	Belongs to the bacterial ribosomal protein bL27 family
QR90_RS13205	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
QR90_RS13210	COG0569	domain protein
QR90_RS13230	COG1428	Deoxynucleoside kinase
QR90_RS13235	COG1428	Deoxynucleoside kinase
QR90_RS13265	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
QR90_RS13280	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
QR90_RS13285	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
QR90_RS13305	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
QR90_RS13345	COG2304	oxidoreductase activity
QR90_RS13390	COG0315	cyclic pyranopterin monophosphate synthase activity
QR90_RS13400	COG1396	sequence-specific DNA binding
QR90_RS13410	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
QR90_RS13425	COG0166	Belongs to the GPI family
QR90_RS13440	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
QR90_RS13470	COG2205	protein histidine kinase activity
QR90_RS13470	COG2198	Histidine kinase
QR90_RS13470	COG0784	Response regulator, receiver
QR90_RS13515	COG1595	DNA-templated transcription, initiation
QR90_RS13520	COG1321	iron dependent repressor
QR90_RS13550	COG0572	uridine kinase
QR90_RS13555	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
QR90_RS13560	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
QR90_RS13565	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
QR90_RS13570	COG1674	ftsk spoiiie
QR90_RS13575	COG1310	metal-dependent protease of the Pad1 Jab1 superfamily
QR90_RS13585	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
QR90_RS13590	COG0772	Belongs to the SEDS family
QR90_RS13615	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
QR90_RS13620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
QR90_RS13630	COG0438	transferase activity, transferring glycosyl groups
QR90_RS13635	COG1358	cellular component organization or biogenesis
QR90_RS13660	COG2304	oxidoreductase activity
QR90_RS13680	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
QR90_RS13700	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
QR90_RS13710	COG2224	Isocitrate lyase
QR90_RS13720	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
QR90_RS13730	COG2815	serine threonine protein kinase
QR90_RS13730	COG0515	serine threonine protein kinase
QR90_RS13735	COG0419	ATPase involved in DNA repair
QR90_RS13740	COG0420	3'-5' exonuclease activity
QR90_RS13750	COG0750	zinc metalloprotease
QR90_RS13755	COG0439	Biotin carboxylase
QR90_RS13770	COG1363	Peptidase, m42
QR90_RS13775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
QR90_RS13780	COG1482	cell wall glycoprotein biosynthetic process
QR90_RS13785	COG0604	alcohol dehydrogenase
QR90_RS13785	COG3321	synthase
QR90_RS13805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
QR90_RS13825	COG0070	glutamate synthase
QR90_RS13825	COG0069	glutamate synthase activity
QR90_RS13825	COG0067	glutamate synthase
QR90_RS13840	COG2385	sporulation resulting in formation of a cellular spore
QR90_RS13850	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
QR90_RS13855	COG0606	chelatase, subunit chli
QR90_RS13875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
QR90_RS13880	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
QR90_RS13900	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
QR90_RS13900	COG0515	serine threonine protein kinase
QR90_RS13915	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
QR90_RS13930	COG0544	peptidyl-prolyl cis-trans isomerase activity
QR90_RS13935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
QR90_RS13940	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
QR90_RS13955	COG1028	Short-chain dehydrogenase reductase Sdr
QR90_RS13960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
QR90_RS13965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
QR90_RS13970	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
QR90_RS13980	COG0789	Transcriptional regulator
QR90_RS13985	COG0584	glycerophosphoryl diester phosphodiesterase
QR90_RS14010	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
QR90_RS14015	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
QR90_RS14020	COG1506	peptidase
QR90_RS14020	COG4946	Tricorn protease homolog
QR90_RS14020	COG0823	Involved in the tonB-independent uptake of proteins
QR90_RS14025	COG1077	Cell shape determining protein MreB Mrl
QR90_RS14030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
QR90_RS14040	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
QR90_RS14045	COG0726	polysaccharide deacetylase
QR90_RS14060	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
QR90_RS14070	COG0494	nUDIX hydrolase
QR90_RS14075	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
QR90_RS14080	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
QR90_RS14085	COG0789	Transcriptional regulator
QR90_RS14095	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
QR90_RS14100	COG0513	Belongs to the DEAD box helicase family
QR90_RS14115	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
QR90_RS14130	COG2897	thiosulfate sulfurtransferase activity
QR90_RS14145	COG0708	Exodeoxyribonuclease III
QR90_RS14150	COG3135	benzoate transporter
QR90_RS14155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
QR90_RS14165	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
QR90_RS14170	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
QR90_RS14195	COG1653	transport
QR90_RS14200	COG1175	transmembrane transport
QR90_RS14205	COG0395	ABC-type sugar transport system, permease component
QR90_RS14235	COG0217	transcriptional regulatory protein
QR90_RS14250	COG0745	RESPONSE REGULATOR receiver
QR90_RS14255	COG3437	response regulator, receiver
QR90_RS14255	COG0784	Response regulator, receiver
QR90_RS14275	COG0477	Major facilitator Superfamily
QR90_RS14280	COG0772	Belongs to the SEDS family
QR90_RS14285	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
QR90_RS14290	COG2894	cell division
QR90_RS14295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
QR90_RS14305	COG2313	pseudouridylate synthase activity
QR90_RS14310	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
QR90_RS14315	COG0745	RESPONSE REGULATOR receiver
QR90_RS14320	COG2205	protein histidine kinase activity
QR90_RS14325	COG0704	Plays a role in the regulation of phosphate uptake
QR90_RS14335	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
QR90_RS14375	COG0494	nUDIX hydrolase
QR90_RS14390	COG0463	Glycosyl transferase, family 2
QR90_RS14425	COG2323	membrane
QR90_RS14435	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
QR90_RS14440	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
QR90_RS14445	COG1268	BioY protein
QR90_RS14480	COG0135	phosphoribosylanthranilate isomerase activity
QR90_RS14495	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
QR90_RS14505	COG1136	(ABC) transporter
QR90_RS14505	COG0577	efflux transmembrane transporter activity
QR90_RS14510	COG1136	(ABC) transporter
QR90_RS14510	COG0577	efflux transmembrane transporter activity
QR90_RS14520	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
QR90_RS14530	COG0508	dehydrogenase complex catalyzes the overall conversion of
QR90_RS14550	COG4895	conserved protein (DUF2196)
QR90_RS14570	COG0567	Dehydrogenase, E1 component
QR90_RS14575	COG0556	nucleotide-excision repair
QR90_RS14580	COG2337	Toxic component of a toxin-antitoxin (TA) module
QR90_RS14595	COG0583	DNA-binding transcription factor activity
QR90_RS14600	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
QR90_RS14605	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
QR90_RS14620	COG0047	phosphoribosylformylglycinamidine synthase activity
QR90_RS14630	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
QR90_RS14635	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
QR90_RS14660	COG0517	IMP dehydrogenase activity
QR90_RS14660	COG0516	GMP reductase activity
QR90_RS14665	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
QR90_RS14670	COG1496	oxidoreductase activity
QR90_RS14675	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
QR90_RS14680	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
QR90_RS14690	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
QR90_RS14695	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
QR90_RS14700	COG0740	serine-type endopeptidase activity
QR90_RS14710	COG4978	Transcriptional regulator
QR90_RS14710	COG0789	Transcriptional regulator
QR90_RS14715	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
QR90_RS14725	COG4251	negative regulation of phosphorylation
QR90_RS14730	COG0784	Response regulator, receiver
QR90_RS14745	COG2095	MarC family integral membrane protein
QR90_RS14760	COG0513	Belongs to the DEAD box helicase family
QR90_RS14775	COG0372	Belongs to the citrate synthase family
QR90_RS14780	COG1028	Short-chain dehydrogenase reductase Sdr
QR90_RS14795	COG0039	L-malate dehydrogenase activity
QR90_RS14830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
QR90_RS14840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
QR90_RS14845	COG1970	mechanosensitive ion channel activity
QR90_RS14850	COG2873	o-acetylhomoserine
QR90_RS14860	COG0545	Peptidyl-prolyl cis-trans isomerase
QR90_RS14865	COG0681	Belongs to the peptidase S26 family
QR90_RS14875	COG0488	(ABC) transporter
QR90_RS14880	COG5504	Zn-dependent protease
QR90_RS14885	COG1108	ABC-type Mn2 Zn2 transport systems permease components
QR90_RS14890	COG1121	(ABC) transporter
QR90_RS14920	COG0456	acetyltransferase
QR90_RS14925	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
QR90_RS14930	COG0404	The glycine cleavage system catalyzes the degradation of glycine
QR90_RS14935	COG0509	glycine decarboxylation via glycine cleavage system
QR90_RS14940	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
QR90_RS14940	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
QR90_RS14975	COG2340	Cysteine-rich secretory protein family
QR90_RS14985	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
QR90_RS15000	COG0564	pseudouridine synthase activity
QR90_RS15015	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
QR90_RS15020	COG1595	DNA-templated transcription, initiation
QR90_RS15040	COG1174	glycine betaine transport
QR90_RS15045	COG0517	IMP dehydrogenase activity
QR90_RS15045	COG1125	glycine betaine transport
QR90_RS15050	COG1174	glycine betaine transport
QR90_RS15055	COG1732	Glycine betaine
QR90_RS15075	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
QR90_RS15080	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
QR90_RS15090	COG1331	Highly conserved protein containing a thioredoxin domain
QR90_RS15105	COG0583	DNA-binding transcription factor activity
QR90_RS15145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
QR90_RS15150	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
QR90_RS15185	COG0438	transferase activity, transferring glycosyl groups
QR90_RS15190	COG2244	polysaccharide biosynthetic process
QR90_RS15230	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
QR90_RS15240	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
QR90_RS15245	COG2856	Zn peptidase
QR90_RS15260	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
QR90_RS15265	COG2815	serine threonine protein kinase
QR90_RS15265	COG0515	serine threonine protein kinase
QR90_RS15270	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
QR90_RS15290	COG2309	aminopeptidase activity
QR90_RS15295	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
QR90_RS15300	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
QR90_RS15320	COG2860	membrane
QR90_RS15335	COG0861	Integral membrane protein TerC family
QR90_RS15355	COG2177	Part of the ABC transporter FtsEX involved in
QR90_RS15360	COG2884	Cell division ATP-binding protein ftsE
QR90_RS15365	COG0793	Belongs to the peptidase S41A family
QR90_RS15370	COG0360	Binds together with S18 to 16S ribosomal RNA
QR90_RS15375	COG0629	single-stranded DNA binding
QR90_RS15380	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
QR90_RS15385	COG0359	binds to the 23S rRNA
QR90_RS15390	COG1506	peptidase
QR90_RS15395	COG1418	mRNA catabolic process
QR90_RS15440	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
QR90_RS15445	COG4106	trans-aconitate 2-methyltransferase activity
QR90_RS15470	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
QR90_RS15480	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
QR90_RS15485	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
QR90_RS15500	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
QR90_RS15515	COG1160	GTP binding
QR90_RS15530	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
QR90_RS15545	COG0706	membrane insertase activity
QR90_RS15560	COG0230	Belongs to the bacterial ribosomal protein bL34 family
QR90_RS15570	COG3960	tartronate-semialdehyde synthase activity
QR90_RS15575	COG3622	Belongs to the hyi family
QR90_RS15580	COG2084	Dehydrogenase
QR90_RS15590	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
QR90_RS15595	COG2720	vancomycin resistance protein
QR90_RS15605	COG4948	Mandelate Racemase Muconate Lactonizing
QR90_RS15615	COG1404	Belongs to the peptidase S8 family
QR90_RS15630	COG0123	including yeast histone deacetylase and acetoin utilization protein
QR90_RS15640	COG0598	Magnesium transport protein CorA
QR90_RS15645	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
QR90_RS15650	COG1570	exodeoxyribonuclease VII activity
QR90_RS15675	COG0165	Argininosuccinate lyase
QR90_RS15685	COG0137	argininosuccinate synthase activity
QR90_RS15695	COG1607	acyl-coa hydrolase
QR90_RS15710	COG4214	carbohydrate transport
QR90_RS15730	COG0180	Tryptophanyl-tRNA synthetase
QR90_RS15740	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
QR90_RS15745	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
QR90_RS15765	COG0799	negative regulation of ribosome biogenesis
QR90_RS15785	COG0742	ribosomal rna small subunit methyltransferase
QR90_RS15790	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
QR90_RS15800	COG2890	protein-(glutamine-N5) methyltransferase activity
QR90_RS15805	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
QR90_RS15825	COG0492	ferredoxin-NADP+ reductase activity
QR90_RS15840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
QR90_RS15850	COG1205	dead DEAH box helicase
QR90_RS15850	COG1111	helicase
QR90_RS15855	COG0436	Aminotransferase
QR90_RS15865	COG0083	homoserine kinase activity
QR90_RS15885	COG2050	protein possibly involved in aromatic compounds catabolism
QR90_RS15890	COG1233	COG1233 Phytoene dehydrogenase and related
QR90_RS15905	COG0803	Belongs to the bacterial solute-binding protein 9 family
QR90_RS15915	COG1028	Short-chain dehydrogenase reductase Sdr
QR90_RS15935	COG2326	polyphosphate kinase activity
QR90_RS15955	COG1012	belongs to the aldehyde dehydrogenase family
QR90_RS15980	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
QR90_RS15985	COG0085	RNA polymerase activity
QR90_RS15990	COG1960	acyl-CoA dehydrogenase activity
QR90_RS15995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
QR90_RS16000	COG0601	transmembrane transport
QR90_RS16015	COG4221	oxidoreductase activity
QR90_RS16030	COG1028	Short-chain dehydrogenase reductase Sdr
QR90_RS16050	COG4608	Belongs to the ABC transporter superfamily
QR90_RS16060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
QR90_RS16065	COG0601	transmembrane transport
QR90_RS16070	COG0747	negative chemotaxis
QR90_RS16075	COG1619	proteins homologs of microcin C7 resistance protein MccF
QR90_RS16080	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
QR90_RS16090	COG3206	protein involved in exopolysaccharide biosynthesis
QR90_RS16095	COG1024	Enoyl-CoA hydratase
QR90_RS16110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
QR90_RS16125	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
QR90_RS16130	COG0460	homoserine dehydrogenase
QR90_RS16140	COG0802	atpase or kinase
QR90_RS16170	COG0857	belongs to the CobB CobQ family
QR90_RS16170	COG0280	phosphate acetyltransferase
QR90_RS16175	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
QR90_RS16185	COG1090	epimerase
QR90_RS16190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
QR90_RS16200	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
QR90_RS16205	COG1414	Transcriptional regulator
QR90_RS16210	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
QR90_RS16220	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
QR90_RS16230	COG0281	malic enzyme
QR90_RS16235	COG1511	domain protein
QR90_RS16245	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
QR90_RS16255	COG1960	acyl-CoA dehydrogenase activity
QR90_RS16280	COG0584	glycerophosphoryl diester phosphodiesterase
QR90_RS16285	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
QR90_RS16290	COG0432	Pfam Uncharacterised protein family UPF0047
QR90_RS16295	COG1454	alcohol dehydrogenase
QR90_RS16300	COG0792	nuclease activity
QR90_RS16305	COG0546	phosphoglycolate phosphatase activity
QR90_RS16310	COG0571	ribonuclease III activity
QR90_RS16345	COG4946	Tricorn protease homolog
QR90_RS16345	COG1506	peptidase
QR90_RS16345	COG0823	Involved in the tonB-independent uptake of proteins
QR90_RS16355	COG0114	fumarate hydratase activity
QR90_RS16370	COG0156	8-amino-7-oxononanoate synthase activity
QR90_RS16380	COG2226	methyltransferase
QR90_RS16390	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
QR90_RS16395	COG2233	PERMEase
QR90_RS16405	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
QR90_RS16410	COG1438	arginine binding
QR90_RS16415	COG2814	Major facilitator Superfamily
QR90_RS16440	COG0492	ferredoxin-NADP+ reductase activity
QR90_RS16445	COG2720	vancomycin resistance protein
QR90_RS16450	COG1475	DNA binding
QR90_RS16455	COG1192	Involved in chromosome partitioning
QR90_RS16460	COG0357	Ribosomal RNA small subunit methyltransferase G
QR90_RS16470	COG0445	tRNA wobble uridine modification
QR90_RS16480	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
QR90_RS16485	COG0022	dehydrogenase e1 component
QR90_RS16495	COG0508	dehydrogenase complex catalyzes the overall conversion of
QR90_RS16505	COG0745	RESPONSE REGULATOR receiver
QR90_RS16515	COG0758	DNA mediated transformation
QR90_RS16550	COG1051	belongs to the nudix hydrolase family
QR90_RS16565	COG0438	transferase activity, transferring glycosyl groups
QR90_RS16600	COG3706	GGDEF domain
QR90_RS16605	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
QR90_RS16635	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
QR90_RS16650	COG3525	Glycosyl hydrolase, family 20, catalytic domain
QR90_RS16660	COG4585	Histidine kinase
QR90_RS16665	COG3561	AntA/AntB antirepressor
QR90_RS16685	COG2813	Specifically methylates the guanine in position
QR90_RS16685	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
QR90_RS16700	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
QR90_RS16710	COG2226	methyltransferase
QR90_RS16725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
QR90_RS16745	COG1401	restriction endodeoxyribonuclease activity
QR90_RS16745	COG1401	restriction endodeoxyribonuclease activity
QR90_RS16755	COG0738	Major facilitator superfamily
QR90_RS16785	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
QR90_RS16795	COG3706	GGDEF domain
QR90_RS16840	COG4251	negative regulation of phosphorylation
QR90_RS16855	COG4251	negative regulation of phosphorylation
QR90_RS16870	COG4251	negative regulation of phosphorylation
QR90_RS16900	COG0366	Alpha amylase catalytic
QR90_RS16900	COG1470	cell adhesion involved in biofilm formation
QR90_RS16950	COG0463	Glycosyl transferase, family 2
QR90_RS16950	COG1216	Glycosyl transferase, family 2
QR90_RS16965	COG4251	negative regulation of phosphorylation
QR90_RS16970	COG3300	MHYT domain
QR90_RS16970	COG5001	Diguanylate cyclase
QR90_RS16985	COG2204	response regulator