locus-tag	class	description
H0G62_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H0G62_RS00020	COG0583	DNA-binding transcription factor activity
H0G62_RS00025	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
H0G62_RS00030	COG0511	ligase activity, forming carbon-carbon bonds
H0G62_RS00045	COG1984	allophanate hydrolase subunit 2
H0G62_RS00075	COG2205	protein histidine kinase activity
H0G62_RS00105	COG1199	ATP-dependent helicase activity
H0G62_RS00120	COG2974	May be involved in recombination
H0G62_RS00125	COG0183	Belongs to the thiolase family
H0G62_RS00130	COG1024	Enoyl-CoA hydratase
H0G62_RS00135	COG1022	Amp-dependent synthetase and ligase
H0G62_RS00170	COG0789	Transcriptional regulator
H0G62_RS00185	COG1902	pentaerythritol trinitrate reductase activity
H0G62_RS00230	COG0445	tRNA wobble uridine modification
H0G62_RS00235	COG0357	Ribosomal RNA small subunit methyltransferase G
H0G62_RS00240	COG1280	lysine exporter protein (LysE YggA)
H0G62_RS00245	COG1192	Involved in chromosome partitioning
H0G62_RS00255	COG1475	DNA binding
H0G62_RS00320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H0G62_RS00330	COG0277	FAD linked oxidase domain protein
H0G62_RS00340	COG2096	Adenosyltransferase
H0G62_RS00350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H0G62_RS00355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0G62_RS00380	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H0G62_RS00380	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
H0G62_RS00415	COG2050	protein possibly involved in aromatic compounds catabolism
H0G62_RS00425	COG2233	PERMEase
H0G62_RS00430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H0G62_RS00435	COG1960	acyl-CoA dehydrogenase activity
H0G62_RS00440	COG1960	acyl-CoA dehydrogenase activity
H0G62_RS00450	COG0850	regulation of cytokinetic process
H0G62_RS00460	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
H0G62_RS00465	COG2205	protein histidine kinase activity
H0G62_RS00470	COG0745	RESPONSE REGULATOR receiver
H0G62_RS00490	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0G62_RS00495	COG1199	ATP-dependent helicase activity
H0G62_RS00495	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H0G62_RS00500	COG1846	Transcriptional regulator
H0G62_RS00515	COG3971	2-oxopent-4-enoate hydratase activity
H0G62_RS00535	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS00540	COG1012	belongs to the aldehyde dehydrogenase family
H0G62_RS00550	COG0179	Fumarylacetoacetate (FAA) hydrolase
H0G62_RS00580	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
H0G62_RS00590	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H0G62_RS00620	COG5002	protein histidine kinase activity
H0G62_RS00625	COG0745	RESPONSE REGULATOR receiver
H0G62_RS00675	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H0G62_RS00725	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H0G62_RS00740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H0G62_RS00750	COG2188	Transcriptional regulator
H0G62_RS00755	COG2986	histidine ammonia-lyase
H0G62_RS00760	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
H0G62_RS00770	COG1228	amidohydrolase
H0G62_RS00775	COG0277	FAD linked oxidase domain protein
H0G62_RS00780	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H0G62_RS00795	COG0789	Transcriptional regulator
H0G62_RS00825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0G62_RS00835	COG1538	Outer membrane efflux protein
H0G62_RS00875	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H0G62_RS00880	COG0583	DNA-binding transcription factor activity
H0G62_RS00890	COG1960	acyl-CoA dehydrogenase activity
H0G62_RS00925	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H0G62_RS00930	COG0154	amidase activity
H0G62_RS00940	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS00945	COG0318	PFAM AMP-dependent synthetase and ligase
H0G62_RS00975	COG3668	Plasmid stabilization system
H0G62_RS00980	COG3609	addiction module antidote protein, CC2985 family
H0G62_RS00985	COG0183	Belongs to the thiolase family
H0G62_RS00990	COG0427	acetyl-CoA hydrolase
H0G62_RS00995	COG1024	Enoyl-CoA hydratase
H0G62_RS01000	COG2030	dehydratase
H0G62_RS01005	COG1028	Short-chain dehydrogenase reductase Sdr
H0G62_RS01010	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
H0G62_RS01015	COG1960	acyl-CoA dehydrogenase activity
H0G62_RS01040	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS01060	COG0318	PFAM AMP-dependent synthetase and ligase
H0G62_RS01070	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H0G62_RS01075	COG3971	2-oxopent-4-enoate hydratase activity
H0G62_RS01080	COG2326	polyphosphate kinase activity
H0G62_RS01110	COG2198	Histidine kinase
H0G62_RS01110	COG0784	Response regulator, receiver
H0G62_RS01110	COG2205	protein histidine kinase activity
H0G62_RS01155	COG0765	amino acid transport
H0G62_RS01160	COG0765	amino acid transport
H0G62_RS01170	COG2186	Transcriptional regulator
H0G62_RS01175	COG1410	methionine synthase
H0G62_RS01175	COG0646	methionine synthase
H0G62_RS01180	COG0584	glycerophosphoryl diester phosphodiesterase
H0G62_RS01190	COG1301	dicarboxylic acid transport
H0G62_RS01200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H0G62_RS01220	COG2824	Alkylphosphonate utilization operon protein PhnA
H0G62_RS01235	COG0583	DNA-binding transcription factor activity
H0G62_RS01245	COG1346	cytolysis
H0G62_RS01255	COG1012	belongs to the aldehyde dehydrogenase family
H0G62_RS01265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H0G62_RS01270	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS01275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H0G62_RS01280	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS01285	COG2186	Transcriptional regulator
H0G62_RS01295	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS01310	COG0583	DNA-binding transcription factor activity
H0G62_RS01350	COG1028	Short-chain dehydrogenase reductase Sdr
H0G62_RS01355	COG1414	Transcriptional regulator
H0G62_RS01365	COG0583	DNA-binding transcription factor activity
H0G62_RS01370	COG1028	Short-chain dehydrogenase reductase Sdr
H0G62_RS01390	COG0583	DNA-binding transcription factor activity
H0G62_RS01405	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS01425	COG0583	DNA-binding transcription factor activity
H0G62_RS01430	COG3550	peptidyl-serine autophosphorylation
H0G62_RS01435	COG1396	sequence-specific DNA binding
H0G62_RS01440	COG0606	chelatase, subunit chli
H0G62_RS01460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0G62_RS01475	COG4948	Mandelate Racemase Muconate Lactonizing
H0G62_RS01485	COG1012	belongs to the aldehyde dehydrogenase family
H0G62_RS01490	COG2267	carboxylic ester hydrolase activity
H0G62_RS01500	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS01525	COG3501	Rhs element vgr protein
H0G62_RS01535	COG0347	Belongs to the P(II) protein family
H0G62_RS01540	COG0004	ammonium transporteR
H0G62_RS01550	COG0277	FAD linked oxidase domain protein
H0G62_RS01560	COG0247	lactate metabolic process
H0G62_RS01585	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H0G62_RS01590	COG1846	Transcriptional regulator
H0G62_RS01635	COG1216	Glycosyl transferase, family 2
H0G62_RS01635	COG1442	glycosyl transferase family 8
H0G62_RS01650	COG2814	Major facilitator Superfamily
H0G62_RS01655	COG0583	DNA-binding transcription factor activity
H0G62_RS01665	COG2205	protein histidine kinase activity
H0G62_RS01670	COG0745	RESPONSE REGULATOR receiver
H0G62_RS01675	COG2211	Major facilitator Superfamily
H0G62_RS01700	COG2175	clavaminate synthase activity
H0G62_RS01705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H0G62_RS01725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H0G62_RS01750	COG0708	Exodeoxyribonuclease III
H0G62_RS01755	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H0G62_RS01790	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H0G62_RS01810	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H0G62_RS01815	COG0154	amidase activity
H0G62_RS01820	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H0G62_RS01825	COG1077	Cell shape determining protein MreB Mrl
H0G62_RS01830	COG1792	Involved in formation and maintenance of cell shape
H0G62_RS01840	COG0768	penicillin binding
H0G62_RS01850	COG0765	amino acid transport
H0G62_RS01875	COG1127	ABC transporter
H0G62_RS01890	COG3237	CsbD-like
H0G62_RS01900	COG2703	oxygen carrier activity
H0G62_RS01905	COG2095	MarC family integral membrane protein
H0G62_RS01910	COG1028	Short-chain dehydrogenase reductase Sdr
H0G62_RS01915	COG0412	Dienelactone hydrolase
H0G62_RS01935	COG2197	response regulator
H0G62_RS01940	COG4585	Histidine kinase
H0G62_RS01945	COG0598	Magnesium transport protein CorA
H0G62_RS01965	COG3411	Ferredoxin
H0G62_RS01970	COG2945	thiolester hydrolase activity
H0G62_RS01975	COG1686	Belongs to the peptidase S11 family
H0G62_RS01980	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
H0G62_RS01985	COG0049	tRNA binding
H0G62_RS01990	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H0G62_RS01995	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H0G62_RS02000	COG0051	transcription antitermination factor activity, RNA binding
H0G62_RS02005	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
H0G62_RS02010	COG0088	Forms part of the polypeptide exit tunnel
H0G62_RS02015	COG0089	rRNA binding
H0G62_RS02020	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H0G62_RS02025	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
H0G62_RS02030	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
H0G62_RS02035	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
H0G62_RS02040	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
H0G62_RS02045	COG0255	Belongs to the universal ribosomal protein uL29 family
H0G62_RS02050	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
H0G62_RS02055	COG0678	peroxiredoxin activity
H0G62_RS02070	COG3909	cytochrome
H0G62_RS02075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H0G62_RS02090	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0G62_RS02095	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H0G62_RS02100	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H0G62_RS02105	COG2921	Belongs to the UPF0250 family
H0G62_RS02115	COG0356	it plays a direct role in the translocation of protons across the membrane
H0G62_RS02130	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H0G62_RS02135	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
H0G62_RS02140	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
H0G62_RS02145	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
H0G62_RS02150	COG0355	proton-transporting ATP synthase activity, rotational mechanism
H0G62_RS02200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0G62_RS02230	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H0G62_RS02240	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H0G62_RS02250	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
H0G62_RS02260	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
H0G62_RS02265	COG0222	ribosome binding
H0G62_RS02270	COG0085	RNA polymerase activity
H0G62_RS02275	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H0G62_RS02295	COG5000	phosphorelay sensor kinase activity
H0G62_RS02300	COG2204	response regulator
H0G62_RS02320	COG1959	2 iron, 2 sulfur cluster binding
H0G62_RS02330	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H0G62_RS02335	COG1074	ATP-dependent DNA helicase activity
H0G62_RS02345	COG0625	glutathione transferase activity
H0G62_RS02370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H0G62_RS02390	COG2072	flavoprotein involved in K transport
H0G62_RS02395	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS02415	COG0318	PFAM AMP-dependent synthetase and ligase
H0G62_RS02415	COG0204	Acyl-transferase
H0G62_RS02475	COG0343	queuine tRNA-ribosyltransferase activity
H0G62_RS02500	COG0210	DNA helicase
H0G62_RS02525	COG0679	Auxin Efflux Carrier
H0G62_RS02555	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H0G62_RS02560	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
H0G62_RS02570	COG1024	Enoyl-CoA hydratase
H0G62_RS02575	COG2050	protein possibly involved in aromatic compounds catabolism
H0G62_RS02630	COG1414	Transcriptional regulator
H0G62_RS02645	COG1832	CoA-binding protein
H0G62_RS02650	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H0G62_RS02665	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS02690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0G62_RS02700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0G62_RS02705	COG1191	sigma factor activity
H0G62_RS02720	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H0G62_RS02730	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
H0G62_RS02735	COG0745	RESPONSE REGULATOR receiver
H0G62_RS02785	COG1028	Short-chain dehydrogenase reductase Sdr
H0G62_RS02790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H0G62_RS02805	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H0G62_RS02810	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H0G62_RS02815	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
H0G62_RS02835	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H0G62_RS02850	COG1706	bacterial-type flagellum-dependent cell motility
H0G62_RS02855	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
H0G62_RS02860	COG4786	Flagellar basal body rod
H0G62_RS02875	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
H0G62_RS02880	COG1558	bacterial-type flagellum-dependent cell motility
H0G62_RS02885	COG1815	bacterial-type flagellum-dependent cell motility
H0G62_RS02890	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
H0G62_RS02925	COG1157	protein secretion by the type III secretion system
H0G62_RS02950	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H0G62_RS02960	COG1338	Plays a role in the flagellum-specific transport system
H0G62_RS02975	COG2197	response regulator
H0G62_RS02990	COG0745	RESPONSE REGULATOR receiver
H0G62_RS02995	COG2198	Histidine kinase
H0G62_RS02995	COG0643	Histidine kinase
H0G62_RS03000	COG0835	chemotaxis
H0G62_RS03010	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
H0G62_RS03015	COG2201	protein-glutamate methylesterase activity
H0G62_RS03090	COG1960	acyl-CoA dehydrogenase activity
H0G62_RS03095	COG0288	reversible hydration of carbon dioxide
H0G62_RS03100	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
H0G62_RS03105	COG0183	Belongs to the thiolase family
H0G62_RS03120	COG1960	acyl-CoA dehydrogenase activity
H0G62_RS03135	COG3012	SEC-C Motif Domain Protein
H0G62_RS03140	COG2198	Histidine kinase
H0G62_RS03140	COG0784	Response regulator, receiver
H0G62_RS03140	COG2205	protein histidine kinase activity
H0G62_RS03155	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H0G62_RS03170	COG0318	PFAM AMP-dependent synthetase and ligase
H0G62_RS03175	COG0025	NhaP-type Na H and K H
H0G62_RS03180	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H0G62_RS03185	COG1024	Enoyl-CoA hydratase
H0G62_RS03200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H0G62_RS03210	COG3246	L-lysine catabolic process to acetate
H0G62_RS03215	COG1250	3-hydroxyacyl-CoA dehydrogenase
H0G62_RS03260	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H0G62_RS03265	COG3162	membrane
H0G62_RS03270	COG0477	Major facilitator Superfamily
H0G62_RS03280	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H0G62_RS03285	COG2814	Major facilitator Superfamily
H0G62_RS03290	COG0583	DNA-binding transcription factor activity
H0G62_RS03300	COG0477	Major facilitator Superfamily
H0G62_RS03305	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
H0G62_RS03310	COG1414	Transcriptional regulator
H0G62_RS03315	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H0G62_RS03325	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H0G62_RS03330	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H0G62_RS03355	COG3121	Chaperone
H0G62_RS03385	COG2076	Multidrug Resistance protein
H0G62_RS03405	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H0G62_RS03415	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H0G62_RS03425	COG2205	protein histidine kinase activity
H0G62_RS03430	COG0745	RESPONSE REGULATOR receiver
H0G62_RS03435	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H0G62_RS03445	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H0G62_RS03450	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H0G62_RS03455	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H0G62_RS03460	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H0G62_RS03465	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H0G62_RS03470	COG0316	Belongs to the HesB IscA family
H0G62_RS03475	COG2814	Major facilitator Superfamily
H0G62_RS03485	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H0G62_RS03490	COG2252	PERMEase
H0G62_RS03495	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H0G62_RS03500	COG0739	heme binding
H0G62_RS03505	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H0G62_RS03510	COG0583	DNA-binding transcription factor activity
H0G62_RS03515	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H0G62_RS03525	COG3706	GGDEF domain
H0G62_RS03530	COG1522	sequence-specific DNA binding
H0G62_RS03550	COG4774	siderophore transport
H0G62_RS03555	COG4774	siderophore transport
H0G62_RS03560	COG3712	iron ion homeostasis
H0G62_RS03565	COG1595	DNA-templated transcription, initiation
H0G62_RS03585	COG1309	transcriptional regulator
H0G62_RS03600	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H0G62_RS03630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0G62_RS03645	COG2318	DinB family
H0G62_RS03670	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H0G62_RS03680	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H0G62_RS03730	COG3800	Transcriptional regulator
H0G62_RS03730	COG1396	sequence-specific DNA binding
H0G62_RS03750	COG0583	DNA-binding transcription factor activity
H0G62_RS03760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0G62_RS03765	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H0G62_RS03785	COG3712	iron ion homeostasis
H0G62_RS03815	COG2099	Precorrin-6x reductase
H0G62_RS03830	COG2875	Belongs to the precorrin methyltransferase family
H0G62_RS03840	COG4691	Plasmid stability protein
H0G62_RS03845	COG1487	ribonuclease activity
H0G62_RS03850	COG1064	alcohol dehydrogenase
H0G62_RS03860	COG0038	chloride channel
H0G62_RS03865	COG1285	pathogenesis
H0G62_RS03900	COG0129	dihydroxy-acid dehydratase activity
H0G62_RS03905	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS03910	COG2223	nitrite transmembrane transporter activity
H0G62_RS03940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H0G62_RS03945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H0G62_RS03990	COG0346	lactoylglutathione lyase activity
H0G62_RS03995	COG0475	glutathione-regulated potassium exporter activity
H0G62_RS03995	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H0G62_RS04000	COG4555	ABC transporter
H0G62_RS04025	COG0583	DNA-binding transcription factor activity
H0G62_RS04035	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H0G62_RS04040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H0G62_RS04045	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS04065	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H0G62_RS04070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H0G62_RS04080	COG1045	serine acetyltransferase
H0G62_RS04090	COG1914	H( )-stimulated, divalent metal cation uptake system
H0G62_RS04105	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
H0G62_RS04160	COG1126	abc transporter atp-binding protein
H0G62_RS04165	COG0765	amino acid transport
H0G62_RS04170	COG0765	amino acid transport
H0G62_RS04175	COG0436	Aminotransferase
H0G62_RS04180	COG0277	FAD linked oxidase domain protein
H0G62_RS04210	COG1397	ADP-ribosylglycohydrolase
H0G62_RS04260	COG4771	TonB-dependent receptor
H0G62_RS04270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H0G62_RS04275	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
H0G62_RS04280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H0G62_RS04310	COG0745	RESPONSE REGULATOR receiver
H0G62_RS04330	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
H0G62_RS04340	COG2259	Doxx family
H0G62_RS04345	COG1802	Transcriptional regulator
H0G62_RS04375	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
H0G62_RS04380	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
H0G62_RS04385	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H0G62_RS04390	COG4770	biotin carboxylase activity
H0G62_RS04395	COG0737	Belongs to the 5'-nucleotidase family
H0G62_RS04405	COG0307	riboflavin synthase, alpha
H0G62_RS04425	COG0443	Heat shock 70 kDa protein
H0G62_RS04430	COG0443	Heat shock 70 kDa protein
H0G62_RS04465	COG0583	DNA-binding transcription factor activity
H0G62_RS04470	COG3045	CreA protein
H0G62_RS04475	COG1181	Belongs to the D-alanine--D-alanine ligase family
H0G62_RS04475	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H0G62_RS04480	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H0G62_RS04480	COG0189	ligase activity
H0G62_RS04485	COG1132	(ABC) transporter
H0G62_RS04515	COG0625	glutathione transferase activity
H0G62_RS04525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H0G62_RS04600	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H0G62_RS04605	COG1765	OsmC-like protein
H0G62_RS04610	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
H0G62_RS04625	COG1473	amidohydrolase
H0G62_RS04650	COG0166	Belongs to the GPI family
H0G62_RS04655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0G62_RS04660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0G62_RS04675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H0G62_RS04680	COG0444	Belongs to the ABC transporter superfamily
H0G62_RS04685	COG4608	Belongs to the ABC transporter superfamily
H0G62_RS04690	COG1228	amidohydrolase
H0G62_RS04710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0G62_RS04715	COG0459	protein refolding
H0G62_RS04720	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
H0G62_RS04740	COG1566	PFAM secretion protein HlyD family protein
H0G62_RS04745	COG0577	efflux transmembrane transporter activity
H0G62_RS04745	COG1136	(ABC) transporter
H0G62_RS04750	COG1309	transcriptional regulator
H0G62_RS04785	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H0G62_RS04795	COG1012	belongs to the aldehyde dehydrogenase family
H0G62_RS04800	COG3284	Transcriptional regulator
H0G62_RS04810	COG1414	Transcriptional regulator
H0G62_RS04845	COG0251	oxidation-reduction process
H0G62_RS04855	COG0179	Fumarylacetoacetate (FAA) hydrolase
H0G62_RS04875	COG0523	cobalamin synthesis protein
H0G62_RS04880	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS04895	COG0583	DNA-binding transcription factor activity
H0G62_RS04905	COG0583	DNA-binding transcription factor activity
H0G62_RS04945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H0G62_RS04950	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
H0G62_RS04955	COG1132	(ABC) transporter
H0G62_RS04960	COG1132	(ABC) transporter
H0G62_RS04970	COG1116	anion transmembrane transporter activity
H0G62_RS04970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H0G62_RS04980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H0G62_RS04985	COG2873	o-acetylhomoserine
H0G62_RS05005	COG2011	ABC-type metal ion transport system permease component
H0G62_RS05015	COG0583	DNA-binding transcription factor activity
H0G62_RS05025	COG1056	cytidyltransferase-related domain
H0G62_RS05025	COG1051	belongs to the nudix hydrolase family
H0G62_RS05030	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H0G62_RS05030	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H0G62_RS05035	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H0G62_RS05055	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H0G62_RS05095	COG0438	transferase activity, transferring glycosyl groups
H0G62_RS05110	COG0367	asparagine synthase
H0G62_RS05115	COG0438	transferase activity, transferring glycosyl groups
H0G62_RS05120	COG0367	asparagine synthase
H0G62_RS05160	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
H0G62_RS05170	COG1560	Kdo2-lipid A biosynthetic process
H0G62_RS05175	COG2267	carboxylic ester hydrolase activity
H0G62_RS05180	COG0218	Necessary for normal cell division and for the maintenance of normal septation
H0G62_RS05185	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H0G62_RS05205	COG1175	transmembrane transport
H0G62_RS05210	COG0395	ABC-type sugar transport system, permease component
H0G62_RS05220	COG0246	Mannitol dehydrogenase
H0G62_RS05225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H0G62_RS05230	COG2207	Transcriptional regulator
H0G62_RS05230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H0G62_RS05240	COG1333	cytochrome c biogenesis protein
H0G62_RS05245	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H0G62_RS05250	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H0G62_RS05255	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
H0G62_RS05270	COG1965	Belongs to the frataxin family
H0G62_RS05310	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H0G62_RS05315	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
H0G62_RS05320	COG0232	Belongs to the dGTPase family. Type 2 subfamily
H0G62_RS05335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H0G62_RS05370	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H0G62_RS05380	COG1414	Transcriptional regulator
H0G62_RS05390	COG0070	glutamate synthase
H0G62_RS05390	COG0067	glutamate synthase
H0G62_RS05390	COG0069	glutamate synthase activity
H0G62_RS05405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H0G62_RS05410	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H0G62_RS05415	COG0537	adenosine 5'-monophosphoramidase activity
H0G62_RS05430	COG0140	phosphoribosyl-ATP diphosphatase activity
H0G62_RS05435	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H0G62_RS05440	COG0107	imidazoleglycerol-phosphate synthase activity
H0G62_RS05445	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H0G62_RS05475	COG0438	transferase activity, transferring glycosyl groups
H0G62_RS05500	COG1127	ABC transporter
H0G62_RS05505	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H0G62_RS05510	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H0G62_RS05520	COG2854	intermembrane phospholipid transfer
H0G62_RS05535	COG0842	Transport permease protein
H0G62_RS05540	COG5007	Belongs to the BolA IbaG family
H0G62_RS05545	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H0G62_RS05550	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H0G62_RS05560	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H0G62_RS05575	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H0G62_RS05580	COG0131	Imidazoleglycerol-phosphate dehydratase
H0G62_RS05590	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
H0G62_RS05605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H0G62_RS05615	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H0G62_RS05620	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H0G62_RS05625	COG1970	mechanosensitive ion channel activity
H0G62_RS05630	COG0723	plastoquinol--plastocyanin reductase activity
H0G62_RS05635	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H0G62_RS05640	COG2857	Cytochrome c1
H0G62_RS05645	COG0625	glutathione transferase activity
H0G62_RS05650	COG2969	positive regulation of protein catabolic process
H0G62_RS05665	COG0653	protein targeting
H0G62_RS05670	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H0G62_RS05680	COG0494	nUDIX hydrolase
H0G62_RS05685	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H0G62_RS05690	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
H0G62_RS05695	COG0237	dephospho-CoA kinase activity
H0G62_RS05720	COG0142	geranyltranstransferase activity
H0G62_RS05725	COG0261	This protein binds to 23S rRNA in the presence of protein L20
H0G62_RS05730	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H0G62_RS05735	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H0G62_RS05740	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H0G62_RS05745	COG0494	nUDIX hydrolase
H0G62_RS05750	COG0442	prolyl-tRNA aminoacylation
H0G62_RS05755	COG0741	lytic transglycosylase activity
H0G62_RS05765	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H0G62_RS05770	COG2890	protein-(glutamine-N5) methyltransferase activity
H0G62_RS05775	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H0G62_RS05780	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
H0G62_RS05805	COG3264	Mechanosensitive ion channel
H0G62_RS05805	COG1511	domain protein
H0G62_RS05810	COG0584	glycerophosphoryl diester phosphodiesterase
H0G62_RS05815	COG3842	ATPase activity
H0G62_RS05820	COG0395	ABC-type sugar transport system, permease component
H0G62_RS05830	COG1653	transport
H0G62_RS05850	COG2226	methyltransferase
H0G62_RS05870	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H0G62_RS05895	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
H0G62_RS05915	COG0302	gtp cyclohydrolase
H0G62_RS05950	COG0154	amidase activity
H0G62_RS05955	COG0747	negative chemotaxis
H0G62_RS05960	COG4608	Belongs to the ABC transporter superfamily
H0G62_RS05970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H0G62_RS05980	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H0G62_RS05985	COG0193	aminoacyl-tRNA hydrolase activity
H0G62_RS05990	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
H0G62_RS05995	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H0G62_RS06005	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
H0G62_RS06010	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H0G62_RS06020	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H0G62_RS06040	COG4452	Inner membrane protein CreD
H0G62_RS06045	COG2205	protein histidine kinase activity
H0G62_RS06050	COG0745	RESPONSE REGULATOR receiver
H0G62_RS06065	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H0G62_RS06070	COG1420	regulation of RNA biosynthetic process
H0G62_RS06095	COG0745	RESPONSE REGULATOR receiver
H0G62_RS06105	COG1994	Peptidase M50
H0G62_RS06115	COG0009	L-threonylcarbamoyladenylate synthase
H0G62_RS06120	COG0613	PHP domain protein
H0G62_RS06125	COG0840	transmembrane signaling receptor activity
H0G62_RS06145	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H0G62_RS06175	COG1136	(ABC) transporter
H0G62_RS06185	COG0084	hydrolase, TatD family'
H0G62_RS06200	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H0G62_RS06220	COG1028	Short-chain dehydrogenase reductase Sdr
H0G62_RS06230	COG0697	spore germination
H0G62_RS06245	COG1283	sodium-dependent phosphate transmembrane transporter activity
H0G62_RS06250	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
H0G62_RS06255	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H0G62_RS06260	COG0196	riboflavin kinase activity
H0G62_RS06270	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H0G62_RS06275	COG2205	protein histidine kinase activity
H0G62_RS06280	COG2205	protein histidine kinase activity
H0G62_RS06285	COG0745	RESPONSE REGULATOR receiver
H0G62_RS06295	COG3781	membrane
H0G62_RS06330	COG3451	type IV secretory pathway VirB4
H0G62_RS06340	COG3838	Conjugal transfer protein Trbc
H0G62_RS06345	COG4962	Type ii secretion system protein e
H0G62_RS06365	COG0583	DNA-binding transcription factor activity
H0G62_RS06380	COG1960	acyl-CoA dehydrogenase activity
H0G62_RS06385	COG2814	Major facilitator Superfamily
H0G62_RS06415	COG0318	PFAM AMP-dependent synthetase and ligase
H0G62_RS06420	COG0183	Belongs to the thiolase family
H0G62_RS06445	COG4959	Type IV secretory pathway protease TraF
H0G62_RS06460	COG1192	Involved in chromosome partitioning
H0G62_RS06490	COG5489	Protein of unknown function (DUF736)
H0G62_RS06510	COG4974	Belongs to the 'phage' integrase family
H0G62_RS06515	COG0582	viral genome integration into host DNA
H0G62_RS06520	COG4974	Belongs to the 'phage' integrase family
H0G62_RS06620	COG1349	DNA-binding transcription factor activity
H0G62_RS06625	COG0546	phosphoglycolate phosphatase activity
H0G62_RS06630	COG3842	ATPase activity
H0G62_RS06635	COG1175	transmembrane transport
H0G62_RS06645	COG1653	transport
H0G62_RS06650	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H0G62_RS06690	COG1063	alcohol dehydrogenase
H0G62_RS06715	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS06750	COG0372	Belongs to the citrate synthase family
H0G62_RS06780	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H0G62_RS06785	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS06810	COG0667	Aldo Keto reductase
H0G62_RS06845	COG2159	amidohydrolase
H0G62_RS06855	COG0583	DNA-binding transcription factor activity
H0G62_RS06875	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
H0G62_RS06890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0G62_RS06910	COG0372	Belongs to the citrate synthase family
H0G62_RS06930	COG0789	Transcriptional regulator
H0G62_RS06990	COG1960	acyl-CoA dehydrogenase activity
H0G62_RS06995	COG1960	acyl-CoA dehydrogenase activity
H0G62_RS07005	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H0G62_RS07015	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H0G62_RS07015	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H0G62_RS07025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0G62_RS07030	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H0G62_RS07035	COG0227	Belongs to the bacterial ribosomal protein bL28 family
H0G62_RS07040	COG0492	ferredoxin-NADP+ reductase activity
H0G62_RS07045	COG1674	ftsk spoiiie
H0G62_RS07050	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H0G62_RS07055	COG0840	transmembrane signaling receptor activity
H0G62_RS07065	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H0G62_RS07075	COG4221	oxidoreductase activity
H0G62_RS07090	COG0559	Belongs to the binding-protein-dependent transport system permease family
H0G62_RS07115	COG1392	Phosphate transport regulator
H0G62_RS07120	COG0306	phosphate transporter
H0G62_RS07135	COG0228	four-way junction DNA binding
H0G62_RS07145	COG0336	Belongs to the RNA methyltransferase TrmD family
H0G62_RS07150	COG0335	large ribosomal subunit rRNA binding
H0G62_RS07160	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
H0G62_RS07165	COG1162	GTPase activity
H0G62_RS07170	COG2154	pterin-4-alpha-carbinolamine dehydratase
H0G62_RS07175	COG0501	Belongs to the peptidase M48B family
H0G62_RS07180	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H0G62_RS07185	COG0513	Belongs to the DEAD box helicase family
H0G62_RS07190	COG3300	MHYT domain
H0G62_RS07190	COG5001	Diguanylate cyclase
H0G62_RS07195	COG2814	Major facilitator Superfamily
H0G62_RS07205	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H0G62_RS07225	COG0516	GMP reductase activity
H0G62_RS07230	COG0210	DNA helicase
H0G62_RS07250	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H0G62_RS07265	COG0412	Dienelactone hydrolase
H0G62_RS07290	COG0251	oxidation-reduction process
H0G62_RS07300	COG3279	Response regulator of the LytR AlgR family
H0G62_RS07305	COG3275	phosphorelay sensor kinase activity
H0G62_RS07310	COG0165	Argininosuccinate lyase
H0G62_RS07340	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H0G62_RS07355	COG3842	ATPase activity
H0G62_RS07370	COG0395	ABC-type sugar transport system, permease component
H0G62_RS07395	COG1309	transcriptional regulator
H0G62_RS07425	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H0G62_RS07440	COG1595	DNA-templated transcription, initiation
H0G62_RS07455	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H0G62_RS07460	COG0840	transmembrane signaling receptor activity
H0G62_RS07465	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H0G62_RS07465	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H0G62_RS07475	COG3022	response to hydroperoxide
H0G62_RS07480	COG1530	ribonuclease E activity
H0G62_RS07505	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H0G62_RS07505	COG0616	signal peptide processing
H0G62_RS07510	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H0G62_RS07515	COG0424	maF-like protein
H0G62_RS07520	COG1399	metal-binding, possibly nucleic acid-binding protein
H0G62_RS07525	COG0333	Belongs to the bacterial ribosomal protein bL32 family
H0G62_RS07530	COG0416	fatty acid biosynthetic process
H0G62_RS07535	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H0G62_RS07545	COG1028	Short-chain dehydrogenase reductase Sdr
H0G62_RS07550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H0G62_RS07555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H0G62_RS07575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H0G62_RS07580	COG0481	GTPase activity
H0G62_RS07585	COG0681	Belongs to the peptidase S26 family
H0G62_RS07595	COG0571	ribonuclease III activity
H0G62_RS07600	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H0G62_RS07605	COG1381	Involved in DNA repair and RecF pathway recombination
H0G62_RS07610	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H0G62_RS07615	COG0736	holo-[acyl-carrier-protein] synthase activity
H0G62_RS07620	COG1472	Belongs to the glycosyl hydrolase 3 family
H0G62_RS07630	COG1278	Cold shock
H0G62_RS07640	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
H0G62_RS07650	COG4251	negative regulation of phosphorylation
H0G62_RS07650	COG2203	Gaf domain
H0G62_RS07650	COG3706	GGDEF domain
H0G62_RS07650	COG5001	Diguanylate cyclase
H0G62_RS07660	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H0G62_RS07670	COG0762	integral membrane protein
H0G62_RS07675	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H0G62_RS07680	COG0159	tryptophan synthase activity
H0G62_RS07685	COG0133	tryptophan synthase activity
H0G62_RS07690	COG0135	phosphoribosylanthranilate isomerase activity
H0G62_RS07695	COG0101	tRNA pseudouridine synthase activity
H0G62_RS07715	COG0473	3-isopropylmalate dehydrogenase activity
H0G62_RS07720	COG0066	3-isopropylmalate dehydratase activity
H0G62_RS07730	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
H0G62_RS07745	COG0484	heat shock protein binding
H0G62_RS07750	COG0443	Heat shock 70 kDa protein
H0G62_RS07755	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H0G62_RS07760	COG0360	Binds together with S18 to 16S ribosomal RNA
H0G62_RS07770	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H0G62_RS07775	COG0359	binds to the 23S rRNA
H0G62_RS07790	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
H0G62_RS07795	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H0G62_RS07805	COG0436	Aminotransferase
H0G62_RS07815	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H0G62_RS07820	COG1763	Mo-molybdopterin cofactor biosynthetic process
H0G62_RS07830	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
H0G62_RS07840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H0G62_RS07855	COG0314	molybdopterin synthase activity
H0G62_RS07860	COG0697	spore germination
H0G62_RS07870	COG0542	response to heat
H0G62_RS07890	COG2264	protein methyltransferase activity
H0G62_RS07945	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H0G62_RS07945	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H0G62_RS07980	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
H0G62_RS07990	COG1028	Short-chain dehydrogenase reductase Sdr
H0G62_RS07990	COG0604	alcohol dehydrogenase
H0G62_RS07990	COG3321	synthase
H0G62_RS08010	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H0G62_RS08015	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H0G62_RS08020	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H0G62_RS08025	COG0649	NAD binding
H0G62_RS08045	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
H0G62_RS08050	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H0G62_RS08060	COG0713	ATP synthesis coupled electron transport
H0G62_RS08100	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H0G62_RS08120	COG3609	addiction module antidote protein, CC2985 family
H0G62_RS08135	COG0457	Tetratricopeptide repeat
H0G62_RS08135	COG0463	Glycosyl transferase, family 2
H0G62_RS08155	COG1136	(ABC) transporter
H0G62_RS08160	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
H0G62_RS08165	COG2814	Major facilitator Superfamily
H0G62_RS08210	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H0G62_RS08225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0G62_RS08240	COG0583	DNA-binding transcription factor activity
H0G62_RS08245	COG1473	amidohydrolase
H0G62_RS08255	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H0G62_RS08265	COG0586	Pfam SNARE associated Golgi protein
H0G62_RS08275	COG0860	N-Acetylmuramoyl-L-alanine amidase
H0G62_RS08285	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H0G62_RS08305	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H0G62_RS08325	COG4974	Belongs to the 'phage' integrase family
H0G62_RS08330	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS08335	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
H0G62_RS08340	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
H0G62_RS08345	COG2833	Protein of unknown function (DUF455)
H0G62_RS08355	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H0G62_RS08365	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H0G62_RS08370	COG0148	phosphopyruvate hydratase activity
H0G62_RS08380	COG2877	3-deoxy-8-phosphooctulonate synthase activity
H0G62_RS08385	COG0504	CTP synthase activity
H0G62_RS08390	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H0G62_RS08400	COG0756	dUTP diphosphatase activity
H0G62_RS08410	COG5002	protein histidine kinase activity
H0G62_RS08415	COG0745	RESPONSE REGULATOR receiver
H0G62_RS08435	COG1047	Peptidyl-prolyl cis-trans
H0G62_RS08440	COG1012	belongs to the aldehyde dehydrogenase family
H0G62_RS08450	COG2850	peptidyl-arginine hydroxylation
H0G62_RS08460	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
H0G62_RS08465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H0G62_RS08490	COG1196	nuclear chromosome segregation
H0G62_RS08490	COG0741	lytic transglycosylase activity
H0G62_RS08490	COG0739	heme binding
H0G62_RS08500	COG0840	transmembrane signaling receptor activity
H0G62_RS08515	COG2308	Evidence 4 Homologs of previously reported genes of
H0G62_RS08530	COG2271	Major facilitator Superfamily
H0G62_RS08540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0G62_RS08540	COG2205	protein histidine kinase activity
H0G62_RS08560	COG4206	TonB-dependent receptor
H0G62_RS08570	COG3720	iron ion transport
H0G62_RS08585	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
H0G62_RS08600	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H0G62_RS08630	COG3712	iron ion homeostasis
H0G62_RS08635	COG1595	DNA-templated transcription, initiation
H0G62_RS08655	COG1477	protein flavinylation
H0G62_RS08670	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H0G62_RS08675	COG1012	belongs to the aldehyde dehydrogenase family
H0G62_RS08695	COG2954	triphosphatase activity
H0G62_RS08700	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H0G62_RS08705	COG0358	DNA primase activity
H0G62_RS08730	COG0318	PFAM AMP-dependent synthetase and ligase
H0G62_RS08740	COG0024	Methionine aminopeptidase
H0G62_RS08755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H0G62_RS08765	COG3540	Alkaline phosphatase
H0G62_RS08770	COG3706	GGDEF domain
H0G62_RS08775	COG3321	synthase
H0G62_RS08775	COG1028	Short-chain dehydrogenase reductase Sdr
H0G62_RS08775	COG0604	alcohol dehydrogenase
H0G62_RS08780	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H0G62_RS08785	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H0G62_RS08795	COG0564	pseudouridine synthase activity
H0G62_RS08800	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H0G62_RS08805	COG1187	pseudouridine synthase activity
H0G62_RS08810	COG0105	UTP biosynthetic process
H0G62_RS08815	COG0820	rRNA (adenine-C2-)-methyltransferase activity
H0G62_RS08830	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
H0G62_RS08835	COG0124	histidyl-tRNA synthetase
H0G62_RS08845	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H0G62_RS08850	COG1160	GTP binding
H0G62_RS08855	COG1923	regulation of RNA biosynthetic process
H0G62_RS08860	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H0G62_RS08865	COG0330	HflC and HflK could
H0G62_RS08870	COG0330	HflC and HflK could
H0G62_RS08875	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
H0G62_RS08880	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H0G62_RS08885	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
H0G62_RS08910	COG1058	Belongs to the CinA family
H0G62_RS08910	COG1546	Belongs to the CinA family
H0G62_RS08915	COG0174	glutamine synthetase
H0G62_RS08925	COG3852	Histidine kinase
H0G62_RS08940	COG0708	Exodeoxyribonuclease III
H0G62_RS08955	COG0402	S-adenosylhomocysteine deaminase activity
H0G62_RS08970	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS09020	COG4948	Mandelate Racemase Muconate Lactonizing
H0G62_RS09045	COG4336	lyase activity
H0G62_RS09055	COG2814	Major facilitator Superfamily
H0G62_RS09065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H0G62_RS09070	COG1595	DNA-templated transcription, initiation
H0G62_RS09090	COG3712	iron ion homeostasis
H0G62_RS09100	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H0G62_RS09110	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
H0G62_RS09120	COG0277	FAD linked oxidase domain protein
H0G62_RS09130	COG1295	ribonuclease BN
H0G62_RS09170	COG1125	glycine betaine transport
H0G62_RS09170	COG0517	IMP dehydrogenase activity
H0G62_RS09180	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
H0G62_RS09185	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H0G62_RS09190	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H0G62_RS09195	COG0741	lytic transglycosylase activity
H0G62_RS09230	COG0557	exoribonuclease II activity
H0G62_RS09240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H0G62_RS09245	COG0052	Belongs to the universal ribosomal protein uS2 family
H0G62_RS09250	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
H0G62_RS09255	COG0528	UMP kinase activity
H0G62_RS09260	COG0233	cytoplasmic translational termination
H0G62_RS09270	COG0575	Belongs to the CDS family
H0G62_RS09275	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
H0G62_RS09280	COG0750	zinc metalloprotease
H0G62_RS09295	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H0G62_RS09300	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H0G62_RS09305	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H0G62_RS09310	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H0G62_RS09315	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H0G62_RS09320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H0G62_RS09325	COG0505	Belongs to the CarA family
H0G62_RS09335	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H0G62_RS09350	COG1534	Rna-binding protein
H0G62_RS09360	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H0G62_RS09370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H0G62_RS09380	COG0248	Ppx GppA phosphatase
H0G62_RS09390	COG0248	Ppx GppA phosphatase
H0G62_RS09395	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H0G62_RS09400	COG0573	inorganic phosphate transmembrane transporter activity
H0G62_RS09405	COG0581	inorganic phosphate transmembrane transporter activity
H0G62_RS09410	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H0G62_RS09415	COG0704	Plays a role in the regulation of phosphate uptake
H0G62_RS09440	COG0254	rRNA binding
H0G62_RS09475	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H0G62_RS09480	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
H0G62_RS09485	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H0G62_RS09500	COG1388	LysM domain
H0G62_RS09500	COG0741	lytic transglycosylase activity
H0G62_RS09505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H0G62_RS09510	COG2226	methyltransferase
H0G62_RS09515	COG0328	RNA-DNA hybrid ribonuclease activity
H0G62_RS09520	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H0G62_RS09535	COG2175	clavaminate synthase activity
H0G62_RS09540	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS09555	COG0303	'Molybdopterin
H0G62_RS09560	COG0746	molybdenum cofactor guanylyltransferase activity
H0G62_RS09565	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H0G62_RS09595	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H0G62_RS09605	COG0840	transmembrane signaling receptor activity
H0G62_RS09620	COG0347	Belongs to the P(II) protein family
H0G62_RS09655	COG0028	Belongs to the TPP enzyme family
H0G62_RS09660	COG0440	acetolactate synthase activity
H0G62_RS09670	COG1183	phosphatidylcholine synthase activity
H0G62_RS09675	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H0G62_RS09680	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H0G62_RS09690	COG1414	Transcriptional regulator
H0G62_RS09695	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
H0G62_RS09700	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H0G62_RS09730	COG0242	peptide deformylase activity
H0G62_RS09735	COG2233	PERMEase
H0G62_RS09745	COG0024	Methionine aminopeptidase
H0G62_RS09775	COG0714	Associated with various cellular activities
H0G62_RS09780	COG2425	protein containing a von Willebrand factor type A (vWA) domain
H0G62_RS09785	COG3552	Protein containing von Willebrand factor type A (VWA) domain
H0G62_RS09790	COG2354	Protein conserved in bacteria
H0G62_RS09815	COG0625	glutathione transferase activity
H0G62_RS09825	COG4774	siderophore transport
H0G62_RS09835	COG1595	DNA-templated transcription, initiation
H0G62_RS09840	COG3047	cAMP biosynthetic process
H0G62_RS09845	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
H0G62_RS09850	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H0G62_RS09865	COG3706	GGDEF domain
H0G62_RS09875	COG1024	Enoyl-CoA hydratase
H0G62_RS09880	COG1028	Short-chain dehydrogenase reductase Sdr
H0G62_RS09890	COG0318	PFAM AMP-dependent synthetase and ligase
H0G62_RS09895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H0G62_RS09900	COG0318	PFAM AMP-dependent synthetase and ligase
H0G62_RS09910	COG1024	Enoyl-CoA hydratase
H0G62_RS09935	COG0183	Belongs to the thiolase family
H0G62_RS09945	COG2909	trisaccharide binding
H0G62_RS09950	COG0456	acetyltransferase
H0G62_RS09955	COG0243	molybdopterin cofactor binding
H0G62_RS09965	COG0826	peptidase U32
H0G62_RS09980	COG1619	proteins homologs of microcin C7 resistance protein MccF
H0G62_RS10015	COG3842	ATPase activity
H0G62_RS10025	COG1309	transcriptional regulator
H0G62_RS10030	COG1113	amino acid transport
H0G62_RS10040	COG0667	Aldo Keto reductase
H0G62_RS10050	COG3655	Transcriptional regulator
H0G62_RS10060	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H0G62_RS10065	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
H0G62_RS10085	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
H0G62_RS10100	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS10110	COG3577	Aspartyl protease
H0G62_RS10115	COG1666	GTP binding
H0G62_RS10120	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H0G62_RS10135	COG0583	DNA-binding transcription factor activity
H0G62_RS10140	COG0137	argininosuccinate synthase activity
H0G62_RS10145	COG3123	guanosine phosphorylase activity
H0G62_RS10155	COG1393	Belongs to the ArsC family
H0G62_RS10160	COG0285	dihydrofolate synthase activity
H0G62_RS10185	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H0G62_RS10250	COG0347	Belongs to the P(II) protein family
H0G62_RS10315	COG4774	siderophore transport
H0G62_RS10360	COG1840	ABC-type Fe3 transport system, periplasmic component
H0G62_RS10370	COG0824	Thioesterase
H0G62_RS10375	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H0G62_RS10400	COG1611	Belongs to the LOG family
H0G62_RS10410	COG2212	antiporter activity
H0G62_RS10425	COG1006	Multisubunit Na H antiporter MnhC subunit
H0G62_RS10430	COG2111	Na H antiporter
H0G62_RS10430	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H0G62_RS10445	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
H0G62_RS10455	COG0776	regulation of translation
H0G62_RS10465	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H0G62_RS10470	COG0287	Prephenate dehydrogenase
H0G62_RS10475	COG1605	Chorismate mutase
H0G62_RS10475	COG0077	Prephenate dehydratase
H0G62_RS10495	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H0G62_RS10515	COG2916	Histone family protein nucleoid-structuring protein H-NS
H0G62_RS10540	COG3126	Type III secretion system lipoprotein chaperone (YscW)
H0G62_RS10550	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
H0G62_RS10555	COG0688	phosphatidylethanolamine metabolic process
H0G62_RS10565	COG0492	ferredoxin-NADP+ reductase activity
H0G62_RS10570	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H0G62_RS10575	COG2895	sulfate adenylyltransferase (ATP) activity
H0G62_RS10580	COG0175	sulfate reduction
H0G62_RS10585	COG0175	sulfate reduction
H0G62_RS10630	COG4772	TonB-dependent receptor
H0G62_RS10635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H0G62_RS10635	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
H0G62_RS10640	COG2860	membrane
H0G62_RS10645	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
H0G62_RS10665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H0G62_RS10670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H0G62_RS10675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H0G62_RS10680	COG1116	anion transmembrane transporter activity
H0G62_RS10715	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H0G62_RS10725	COG0670	Belongs to the BI1 family
H0G62_RS10730	COG3193	protein, possibly involved in utilization of glycolate and propanediol
H0G62_RS10780	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H0G62_RS10785	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
H0G62_RS10790	COG0291	Belongs to the bacterial ribosomal protein bL35 family
H0G62_RS10795	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
H0G62_RS10800	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H0G62_RS10805	COG0072	phenylalanine-tRNA ligase activity
H0G62_RS10805	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H0G62_RS10810	COG0776	regulation of translation
H0G62_RS10825	COG0583	DNA-binding transcription factor activity
H0G62_RS10830	COG0277	FAD linked oxidase domain protein
H0G62_RS10830	COG0247	lactate metabolic process
H0G62_RS10850	COG1464	Belongs to the NlpA lipoprotein family
H0G62_RS10860	COG0183	Belongs to the thiolase family
H0G62_RS10865	COG0318	PFAM AMP-dependent synthetase and ligase
H0G62_RS10880	COG1122	ATPase activity
H0G62_RS10885	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H0G62_RS10890	COG2011	ABC-type metal ion transport system permease component
H0G62_RS10895	COG1464	Belongs to the NlpA lipoprotein family
H0G62_RS10915	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H0G62_RS10930	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H0G62_RS10935	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H0G62_RS10940	COG4208	sulfate ABC transporter
H0G62_RS10945	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H0G62_RS10950	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
H0G62_RS10955	COG2376	Dihydroxyacetone kinase
H0G62_RS10960	COG0698	ribose 5-phosphate isomerase
H0G62_RS10965	COG1129	ABC transporter
H0G62_RS10970	COG1879	ABC-type sugar transport system periplasmic component
H0G62_RS10975	COG1028	Short-chain dehydrogenase reductase Sdr
H0G62_RS10980	COG1172	Belongs to the binding-protein-dependent transport system permease family
H0G62_RS10985	COG1063	alcohol dehydrogenase
H0G62_RS10995	COG1280	lysine exporter protein (LysE YggA)
H0G62_RS11010	COG2367	Beta-lactamase
H0G62_RS11015	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H0G62_RS11015	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
H0G62_RS11025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0G62_RS11080	COG1942	4-Oxalocrotonate Tautomerase
H0G62_RS11125	COG1643	Atp-dependent helicase
H0G62_RS11150	COG0318	PFAM AMP-dependent synthetase and ligase
H0G62_RS11180	COG4774	siderophore transport
H0G62_RS11190	COG1959	2 iron, 2 sulfur cluster binding
H0G62_RS11260	COG1116	anion transmembrane transporter activity
H0G62_RS11265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H0G62_RS11275	COG1028	Short-chain dehydrogenase reductase Sdr
H0G62_RS11325	COG2202	Pas domain
H0G62_RS11325	COG2199	diguanylate cyclase activity
H0G62_RS11325	COG2200	EAL domain
H0G62_RS11335	COG1794	racemase activity, acting on amino acids and derivatives
H0G62_RS11340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0G62_RS11350	COG2133	pyrroloquinoline quinone binding
H0G62_RS11360	COG0789	Transcriptional regulator
H0G62_RS11385	COG0513	Belongs to the DEAD box helicase family
H0G62_RS11390	COG5001	Diguanylate cyclase
H0G62_RS11390	COG4251	negative regulation of phosphorylation
H0G62_RS11390	COG3706	GGDEF domain
H0G62_RS11390	COG2203	Gaf domain
H0G62_RS11420	COG1129	ABC transporter
H0G62_RS11430	COG3501	Rhs element vgr protein
H0G62_RS11500	COG1028	Short-chain dehydrogenase reductase Sdr
H0G62_RS11505	COG1024	Enoyl-CoA hydratase
H0G62_RS11555	COG1131	(ABC) transporter
H0G62_RS11595	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS11615	COG2159	amidohydrolase
H0G62_RS11655	COG0667	Aldo Keto reductase
H0G62_RS11665	COG1414	Transcriptional regulator
H0G62_RS11670	COG0477	Major facilitator Superfamily
H0G62_RS11675	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H0G62_RS11690	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
H0G62_RS11695	COG2814	Major facilitator Superfamily
H0G62_RS11710	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS11715	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H0G62_RS11725	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H0G62_RS11755	COG0598	Magnesium transport protein CorA
H0G62_RS11770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H0G62_RS11780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H0G62_RS11795	COG0840	transmembrane signaling receptor activity
H0G62_RS11800	COG4628	conserved protein (DUF2132)
H0G62_RS11815	COG1366	Belongs to the anti-sigma-factor antagonist family
H0G62_RS11820	COG1366	Belongs to the anti-sigma-factor antagonist family
H0G62_RS11825	COG2172	sigma factor antagonist activity
H0G62_RS11835	COG2205	protein histidine kinase activity
H0G62_RS11840	COG0784	Response regulator, receiver
H0G62_RS11840	COG2205	protein histidine kinase activity
H0G62_RS11845	COG0583	DNA-binding transcription factor activity
H0G62_RS11855	COG2329	Antibiotic biosynthesis monooxygenase
H0G62_RS11860	COG3609	addiction module antidote protein, CC2985 family
H0G62_RS11870	COG1280	lysine exporter protein (LysE YggA)
H0G62_RS11880	COG0583	DNA-binding transcription factor activity
H0G62_RS11895	COG1971	Probably functions as a manganese efflux pump
H0G62_RS11945	COG0765	amino acid transport
H0G62_RS11950	COG0765	amino acid transport
H0G62_RS11965	COG1309	transcriptional regulator
H0G62_RS11970	COG0604	alcohol dehydrogenase
H0G62_RS12005	COG0456	acetyltransferase
H0G62_RS12030	COG1272	protein, Hemolysin III
H0G62_RS12050	COG1944	ATP diphosphatase activity
H0G62_RS12065	COG0515	serine threonine protein kinase
H0G62_RS12095	COG1414	Transcriptional regulator
H0G62_RS12100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0G62_RS12150	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H0G62_RS12210	COG1028	Short-chain dehydrogenase reductase Sdr
H0G62_RS12245	COG0564	pseudouridine synthase activity
H0G62_RS12255	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H0G62_RS12255	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H0G62_RS12265	COG0404	The glycine cleavage system catalyzes the degradation of glycine
H0G62_RS12310	COG0583	DNA-binding transcription factor activity
H0G62_RS12325	COG0662	Cupin 2, conserved barrel domain protein
H0G62_RS12330	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
H0G62_RS12335	COG4120	Belongs to the binding-protein-dependent transport system permease family
H0G62_RS12360	COG1609	Transcriptional regulator
H0G62_RS12365	COG0673	inositol 2-dehydrogenase activity
H0G62_RS12375	COG1024	Enoyl-CoA hydratase
H0G62_RS12380	COG1012	belongs to the aldehyde dehydrogenase family
H0G62_RS12390	COG1175	transmembrane transport
H0G62_RS12395	COG0395	ABC-type sugar transport system, permease component
H0G62_RS12400	COG3842	ATPase activity
H0G62_RS12435	COG0583	DNA-binding transcription factor activity
H0G62_RS12440	COG0656	L-ascorbic acid biosynthetic process
H0G62_RS12460	COG1073	alpha beta
H0G62_RS12480	COG0346	lactoylglutathione lyase activity
H0G62_RS12515	COG0840	transmembrane signaling receptor activity
H0G62_RS12525	COG1301	dicarboxylic acid transport
H0G62_RS12530	COG4191	Histidine kinase
H0G62_RS12550	COG1609	Transcriptional regulator
H0G62_RS12570	COG0583	DNA-binding transcription factor activity
H0G62_RS12575	COG0596	Alpha beta hydrolase
H0G62_RS12605	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H0G62_RS12610	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H0G62_RS12625	COG3386	PFAM SMP-30 Gluconolaconase
H0G62_RS12635	COG1902	pentaerythritol trinitrate reductase activity
H0G62_RS12635	COG0446	pyridine nucleotide-disulphide oxidoreductase
H0G62_RS12645	COG0753	catalase activity
H0G62_RS12665	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
H0G62_RS12680	COG0587	DNA-directed DNA polymerase activity
H0G62_RS12695	COG2982	Protein involved in outer membrane biogenesis
H0G62_RS12715	COG3246	L-lysine catabolic process to acetate
H0G62_RS12725	COG1802	Transcriptional regulator
H0G62_RS12740	COG0564	pseudouridine synthase activity
H0G62_RS12795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H0G62_RS12805	COG1309	transcriptional regulator
H0G62_RS12815	COG0642	Histidine kinase
H0G62_RS12825	COG3258	Cytochrome c
H0G62_RS12840	COG0778	Nitroreductase
H0G62_RS12865	COG1253	flavin adenine dinucleotide binding
H0G62_RS12875	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
H0G62_RS12905	COG0714	Associated with various cellular activities
H0G62_RS12915	COG3552	Protein containing von Willebrand factor type A (VWA) domain
H0G62_RS13025	COG2916	Histone family protein nucleoid-structuring protein H-NS
H0G62_RS13040	COG2974	May be involved in recombination
H0G62_RS13355	COG3042	response to heat
H0G62_RS13360	COG2916	Histone family protein nucleoid-structuring protein H-NS
H0G62_RS13365	COG2226	methyltransferase
H0G62_RS13390	COG1612	heme a metabolic process
H0G62_RS13395	COG0109	protoheme IX farnesyltransferase activity
H0G62_RS13400	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
H0G62_RS13415	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H0G62_RS13420	COG1845	cytochrome c oxidase, subunit III
H0G62_RS13425	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H0G62_RS13435	COG0477	Major facilitator Superfamily
H0G62_RS13450	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H0G62_RS13460	COG3706	GGDEF domain
H0G62_RS13465	COG3706	GGDEF domain
H0G62_RS13470	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H0G62_RS13475	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H0G62_RS13480	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
H0G62_RS13490	COG1741	Belongs to the pirin family
H0G62_RS13515	COG3706	GGDEF domain
H0G62_RS13520	COG0659	secondary active sulfate transmembrane transporter activity
H0G62_RS13530	COG0626	cystathionine gamma-synthase activity
H0G62_RS13555	COG4181	ATPase activity
H0G62_RS13560	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
H0G62_RS13565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H0G62_RS13570	COG5507	3-demethylubiquinone-9 3-methyltransferase
H0G62_RS13600	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H0G62_RS13620	COG4178	(ABC) transporter
H0G62_RS13660	COG1473	amidohydrolase
H0G62_RS13665	COG1739	Uncharacterized protein family UPF0029
H0G62_RS13690	COG2207	Transcriptional regulator
H0G62_RS13700	COG5001	Diguanylate cyclase
H0G62_RS13700	COG5002	protein histidine kinase activity
H0G62_RS13705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H0G62_RS13715	COG0556	nucleotide-excision repair
H0G62_RS13720	COG1959	2 iron, 2 sulfur cluster binding
H0G62_RS13725	COG1104	cysteine desulfurase activity
H0G62_RS13730	COG0822	iron-sulfur transferase activity
H0G62_RS13745	COG0443	Heat shock 70 kDa protein
H0G62_RS13800	COG0167	dihydroorotate dehydrogenase activity
H0G62_RS13805	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
H0G62_RS13825	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
H0G62_RS13845	COG0508	dehydrogenase complex catalyzes the overall conversion of
H0G62_RS13850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H0G62_RS13860	COG1280	lysine exporter protein (LysE YggA)
H0G62_RS13885	COG0625	glutathione transferase activity
H0G62_RS13900	COG0791	NLP P60 protein
H0G62_RS13935	COG0745	RESPONSE REGULATOR receiver
H0G62_RS13940	COG1538	Outer membrane efflux protein
H0G62_RS13965	COG1309	transcriptional regulator
H0G62_RS13970	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H0G62_RS14015	COG0259	pyridoxamine-phosphate oxidase activity
H0G62_RS14055	COG2032	superoxide dismutase activity
H0G62_RS14070	COG0346	lactoylglutathione lyase activity
H0G62_RS14075	COG2197	response regulator
H0G62_RS14085	COG2197	response regulator
H0G62_RS14110	COG2080	2 iron, 2 sulfur cluster binding
H0G62_RS14120	COG2010	Cytochrome c
H0G62_RS14120	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H0G62_RS14130	COG1309	transcriptional regulator
H0G62_RS14155	COG3781	membrane
H0G62_RS14165	COG0583	DNA-binding transcription factor activity
H0G62_RS14180	COG2985	domain, Protein
H0G62_RS14195	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS14200	COG1609	Transcriptional regulator
H0G62_RS14300	COG1764	response to oxidative stress
H0G62_RS14305	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
H0G62_RS14310	COG1120	ATPase activity
H0G62_RS14315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H0G62_RS14325	COG4774	siderophore transport
H0G62_RS14330	COG0745	RESPONSE REGULATOR receiver
H0G62_RS14335	COG2205	protein histidine kinase activity
H0G62_RS14355	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0G62_RS14360	COG0702	epimerase
H0G62_RS14365	COG1902	pentaerythritol trinitrate reductase activity
H0G62_RS14370	COG1309	transcriptional regulator
H0G62_RS14465	COG3501	Rhs element vgr protein
H0G62_RS14615	COG1802	Transcriptional regulator
H0G62_RS14625	COG0840	transmembrane signaling receptor activity
H0G62_RS14645	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H0G62_RS14655	COG2205	protein histidine kinase activity
H0G62_RS14670	COG1597	lipid kinase activity
H0G62_RS14675	COG5001	Diguanylate cyclase
H0G62_RS14700	COG2255	four-way junction helicase activity
H0G62_RS14705	COG2080	2 iron, 2 sulfur cluster binding
H0G62_RS14710	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
H0G62_RS14715	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H0G62_RS14740	COG0583	DNA-binding transcription factor activity
H0G62_RS14750	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H0G62_RS14790	COG0667	Aldo Keto reductase
H0G62_RS14845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H0G62_RS14850	COG1120	ATPase activity
H0G62_RS14860	COG0583	DNA-binding transcription factor activity
H0G62_RS14870	COG0840	transmembrane signaling receptor activity
H0G62_RS14890	COG1802	Transcriptional regulator
H0G62_RS14905	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H0G62_RS14950	COG0583	DNA-binding transcription factor activity
H0G62_RS14955	COG3300	MHYT domain
H0G62_RS14955	COG5001	Diguanylate cyclase
H0G62_RS14965	COG0800	Aldolase
H0G62_RS14980	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H0G62_RS14985	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H0G62_RS14990	COG3265	gluconokinase activity
H0G62_RS14995	COG1609	Transcriptional regulator
H0G62_RS15000	COG0784	Response regulator, receiver
H0G62_RS15000	COG0835	chemotaxis
H0G62_RS15005	COG4770	biotin carboxylase activity
H0G62_RS15010	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H0G62_RS15015	COG1703	isobutyryl-CoA mutase activity
H0G62_RS15020	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H0G62_RS15020	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H0G62_RS15025	COG1802	Transcriptional regulator
H0G62_RS15030	COG1022	Amp-dependent synthetase and ligase
H0G62_RS15095	COG1113	amino acid transport
H0G62_RS15100	COG4771	TonB-dependent receptor
H0G62_RS15115	COG2814	Major facilitator Superfamily
H0G62_RS15120	COG2207	Transcriptional regulator
H0G62_RS15130	COG1476	TRANSCRIPTIONal
H0G62_RS15140	COG4206	TonB-dependent receptor
H0G62_RS15150	COG0393	Putative heavy-metal-binding
H0G62_RS15165	COG2916	Histone family protein nucleoid-structuring protein H-NS
H0G62_RS15175	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H0G62_RS15200	COG3135	benzoate transporter
H0G62_RS15210	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H0G62_RS15215	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H0G62_RS15220	COG1752	Esterase of the alpha-beta hydrolase superfamily
H0G62_RS15240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0G62_RS15310	COG0133	tryptophan synthase activity
H0G62_RS15335	COG3300	MHYT domain
H0G62_RS15335	COG5001	Diguanylate cyclase
H0G62_RS15350	COG1686	Belongs to the peptidase S11 family
H0G62_RS15375	COG0784	Response regulator, receiver
H0G62_RS15375	COG4191	Histidine kinase
H0G62_RS15390	COG0583	DNA-binding transcription factor activity
H0G62_RS15410	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS15425	COG1595	DNA-templated transcription, initiation
H0G62_RS15455	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
H0G62_RS15495	COG4774	siderophore transport
H0G62_RS15505	COG1846	Transcriptional regulator
H0G62_RS15515	COG0735	belongs to the Fur family
H0G62_RS15525	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H0G62_RS15530	COG1469	GTP cyclohydrolase I activity
H0G62_RS15535	COG0523	cobalamin synthesis protein
H0G62_RS15550	COG0724	RNA recognition motif
H0G62_RS15570	COG2610	gluconate transmembrane transporter activity
H0G62_RS15575	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H0G62_RS15600	COG3437	response regulator, receiver
H0G62_RS15645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H0G62_RS15660	COG0840	transmembrane signaling receptor activity
H0G62_RS15680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H0G62_RS15685	COG2890	protein-(glutamine-N5) methyltransferase activity
H0G62_RS15695	COG0318	PFAM AMP-dependent synthetase and ligase
H0G62_RS15720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0G62_RS15725	COG4597	amino acid ABC transporter
H0G62_RS15730	COG0765	amino acid transport
H0G62_RS15740	COG1028	Short-chain dehydrogenase reductase Sdr
H0G62_RS15765	COG0625	glutathione transferase activity
H0G62_RS15790	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H0G62_RS15800	COG1196	nuclear chromosome segregation
H0G62_RS15820	COG2828	Protein conserved in bacteria
H0G62_RS15885	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H0G62_RS15890	COG1570	exodeoxyribonuclease VII activity
H0G62_RS15900	COG0811	peptide transport
H0G62_RS15905	COG0848	biopolymer transport protein
H0G62_RS15910	COG1663	tetraacyldisaccharide 4'-kinase activity
H0G62_RS15915	COG2835	tetraacyldisaccharide 4'-kinase activity
H0G62_RS15920	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
H0G62_RS15925	COG0563	adenylate kinase activity
H0G62_RS15930	COG0252	asparaginase activity
H0G62_RS15935	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H0G62_RS15950	COG3712	iron ion homeostasis
H0G62_RS15960	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H0G62_RS15970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H0G62_RS15985	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H0G62_RS16005	COG0583	DNA-binding transcription factor activity
H0G62_RS16010	COG0436	Aminotransferase
H0G62_RS16070	COG0424	maF-like protein
H0G62_RS16075	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
H0G62_RS16080	COG0799	negative regulation of ribosome biogenesis
H0G62_RS16085	COG0408	coproporphyrinogen oxidase activity
H0G62_RS16090	COG0151	Belongs to the GarS family
H0G62_RS16095	COG0217	transcriptional regulatory protein
H0G62_RS16110	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
H0G62_RS16115	COG0217	transcriptional regulatory protein
H0G62_RS16120	COG2133	pyrroloquinoline quinone binding
H0G62_RS16160	COG4106	trans-aconitate 2-methyltransferase activity
H0G62_RS16165	COG0346	lactoylglutathione lyase activity
H0G62_RS16170	COG0700	Nucleoside recognition
H0G62_RS16180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H0G62_RS16185	COG0542	response to heat
H0G62_RS16190	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H0G62_RS16205	COG1199	ATP-dependent helicase activity
H0G62_RS16220	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H0G62_RS16225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H0G62_RS16230	COG0508	dehydrogenase complex catalyzes the overall conversion of
H0G62_RS16250	COG0437	4 iron, 4 sulfur cluster binding
H0G62_RS16255	COG2864	formate dehydrogenase
H0G62_RS16270	COG3276	selenocysteine insertion sequence binding
H0G62_RS16285	COG2199	diguanylate cyclase activity
H0G62_RS16305	COG2366	antibiotic biosynthetic process
H0G62_RS16315	COG2199	diguanylate cyclase activity
H0G62_RS16325	COG2916	Histone family protein nucleoid-structuring protein H-NS
H0G62_RS16330	COG0840	transmembrane signaling receptor activity
H0G62_RS16340	COG3706	GGDEF domain
H0G62_RS16395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H0G62_RS16605	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
H0G62_RS16680	COG2916	Histone family protein nucleoid-structuring protein H-NS
H0G62_RS16710	COG0582	viral genome integration into host DNA
H0G62_RS16720	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H0G62_RS16735	COG0823	Involved in the tonB-independent uptake of proteins
H0G62_RS16740	COG1132	(ABC) transporter
H0G62_RS16745	COG0666	response to abiotic stimulus
H0G62_RS16750	COG0084	hydrolase, TatD family'
H0G62_RS16760	COG0470	DNA polymerase III
H0G62_RS16765	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H0G62_RS16770	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H0G62_RS16805	COG2197	response regulator
H0G62_RS16835	COG2183	response to ionizing radiation
H0G62_RS16840	COG2132	Multicopper oxidase
H0G62_RS16855	COG2329	Antibiotic biosynthesis monooxygenase
H0G62_RS16865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H0G62_RS16875	COG2814	Major facilitator Superfamily
H0G62_RS16880	COG2814	Major facilitator Superfamily
H0G62_RS16895	COG2130	NADP-dependent
H0G62_RS16910	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H0G62_RS16925	COG0148	phosphopyruvate hydratase activity
H0G62_RS16940	COG4772	TonB-dependent receptor
H0G62_RS16955	COG1012	belongs to the aldehyde dehydrogenase family
H0G62_RS16965	COG0277	FAD linked oxidase domain protein
H0G62_RS16970	COG1304	FMN binding
H0G62_RS16975	COG2186	Transcriptional regulator
H0G62_RS16980	COG1620	l-lactate permease
H0G62_RS16985	COG0583	DNA-binding transcription factor activity
H0G62_RS17000	COG1028	Short-chain dehydrogenase reductase Sdr
H0G62_RS17005	COG4948	Mandelate Racemase Muconate Lactonizing
H0G62_RS17010	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
H0G62_RS17015	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
H0G62_RS17020	COG3639	organic phosphonate transmembrane transporter activity
H0G62_RS17065	COG0655	NAD(P)H dehydrogenase (quinone) activity
H0G62_RS17080	COG4774	siderophore transport
H0G62_RS17100	COG0625	glutathione transferase activity
H0G62_RS17105	COG1017	nitric oxide dioxygenase activity
H0G62_RS17105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0G62_RS17150	COG0183	Belongs to the thiolase family
H0G62_RS17175	COG0411	ABC transporter
H0G62_RS17185	COG0559	Belongs to the binding-protein-dependent transport system permease family
H0G62_RS17200	COG0318	PFAM AMP-dependent synthetase and ligase
H0G62_RS17220	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H0G62_RS17225	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H0G62_RS17230	COG2917	probably involved in intracellular septation
H0G62_RS17245	COG4774	siderophore transport
H0G62_RS17260	COG0351	phosphomethylpyrimidine kinase
H0G62_RS17275	COG2022	thiamine diphosphate biosynthetic process
H0G62_RS17310	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H0G62_RS17335	COG4221	oxidoreductase activity
H0G62_RS17355	COG1250	3-hydroxyacyl-CoA dehydrogenase
H0G62_RS17380	COG1136	(ABC) transporter
H0G62_RS17380	COG0577	efflux transmembrane transporter activity
H0G62_RS17385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0G62_RS17430	COG3712	iron ion homeostasis
H0G62_RS17435	COG1595	DNA-templated transcription, initiation
H0G62_RS17445	COG3712	iron ion homeostasis
H0G62_RS17450	COG1595	DNA-templated transcription, initiation
H0G62_RS17460	COG3712	iron ion homeostasis
H0G62_RS17465	COG1595	DNA-templated transcription, initiation
H0G62_RS17480	COG1595	DNA-templated transcription, initiation
H0G62_RS17485	COG2202	Pas domain
H0G62_RS17485	COG2199	diguanylate cyclase activity
H0G62_RS17485	COG2200	EAL domain
H0G62_RS17500	COG0308	aminopeptidase N
H0G62_RS17505	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
H0G62_RS17515	COG0529	Catalyzes the synthesis of activated sulfate
H0G62_RS17560	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
H0G62_RS17575	COG1396	sequence-specific DNA binding
H0G62_RS17595	COG1349	DNA-binding transcription factor activity
H0G62_RS17600	COG1879	ABC-type sugar transport system periplasmic component
H0G62_RS17605	COG1129	ABC transporter
H0G62_RS17610	COG1172	Belongs to the binding-protein-dependent transport system permease family
H0G62_RS17615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H0G62_RS17625	COG0583	DNA-binding transcription factor activity
H0G62_RS17640	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
H0G62_RS17650	COG2011	ABC-type metal ion transport system permease component
H0G62_RS17655	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H0G62_RS17660	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H0G62_RS17665	COG2080	2 iron, 2 sulfur cluster binding
H0G62_RS17705	COG0583	DNA-binding transcription factor activity
H0G62_RS17730	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H0G62_RS17735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H0G62_RS17740	COG4592	Periplasmic binding protein
H0G62_RS17745	COG1120	ATPase activity
H0G62_RS17755	COG1629	transport
H0G62_RS17755	COG4774	siderophore transport
H0G62_RS17765	COG0745	RESPONSE REGULATOR receiver
H0G62_RS17770	COG2205	protein histidine kinase activity
H0G62_RS17785	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
H0G62_RS17795	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS17800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H0G62_RS17815	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
H0G62_RS17820	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H0G62_RS17830	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
H0G62_RS17845	COG1609	Transcriptional regulator
H0G62_RS17855	COG4208	sulfate ABC transporter
H0G62_RS17865	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H0G62_RS17870	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H0G62_RS17885	COG1522	sequence-specific DNA binding
H0G62_RS17890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H0G62_RS17900	COG3119	arylsulfatase activity
H0G62_RS17920	COG0864	Transcriptional regulator
H0G62_RS17945	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H0G62_RS17955	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H0G62_RS17960	COG0697	spore germination
H0G62_RS17965	COG1846	Transcriptional regulator
H0G62_RS18005	COG1595	DNA-templated transcription, initiation
H0G62_RS18065	COG0840	transmembrane signaling receptor activity
H0G62_RS18070	COG0583	DNA-binding transcription factor activity
H0G62_RS18080	COG2197	response regulator
H0G62_RS18090	COG2203	Gaf domain
H0G62_RS18090	COG2200	EAL domain
H0G62_RS18090	COG2199	diguanylate cyclase activity
H0G62_RS18095	COG2205	protein histidine kinase activity
H0G62_RS18095	COG0784	Response regulator, receiver
H0G62_RS18120	COG0069	glutamate synthase activity
H0G62_RS18130	COG0745	RESPONSE REGULATOR receiver
H0G62_RS18135	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H0G62_RS18145	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H0G62_RS18165	COG4774	siderophore transport
H0G62_RS18175	COG1802	Transcriptional regulator
H0G62_RS18180	COG3193	protein, possibly involved in utilization of glycolate and propanediol
H0G62_RS18185	COG0247	lactate metabolic process
H0G62_RS18190	COG1802	Transcriptional regulator
H0G62_RS18230	COG1201	RNA secondary structure unwinding
H0G62_RS18235	COG1793	dna ligase
H0G62_RS18240	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
H0G62_RS18240	COG1793	dna ligase
H0G62_RS18295	COG1181	Belongs to the D-alanine--D-alanine ligase family
H0G62_RS18305	COG1301	dicarboxylic acid transport
H0G62_RS18320	COG1027	Aspartate ammonia-lyase
H0G62_RS18325	COG2814	Major facilitator Superfamily
H0G62_RS18335	COG0583	DNA-binding transcription factor activity
H0G62_RS18355	COG2072	flavoprotein involved in K transport
H0G62_RS18385	COG2368	4-hydroxyphenylacetate
H0G62_RS18395	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H0G62_RS18400	COG1902	pentaerythritol trinitrate reductase activity
H0G62_RS18455	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H0G62_RS18455	COG0519	Catalyzes the synthesis of GMP from XMP
H0G62_RS18470	COG0583	DNA-binding transcription factor activity
H0G62_RS18495	COG2867	negative regulation of translational initiation
H0G62_RS18500	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
H0G62_RS18530	COG1024	Enoyl-CoA hydratase
H0G62_RS18550	COG0583	DNA-binding transcription factor activity
H0G62_RS18560	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H0G62_RS18565	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H0G62_RS18570	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
H0G62_RS18575	COG0195	Participates in both transcription termination and antitermination
H0G62_RS18580	COG0779	Required for maturation of 30S ribosomal subunits
H0G62_RS18590	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H0G62_RS18590	COG2010	Cytochrome c
H0G62_RS18595	COG2863	cytochrome
H0G62_RS18615	COG3040	lipid binding
H0G62_RS18620	COG4172	Belongs to the ABC transporter superfamily
H0G62_RS18625	COG4239	(ABC) transporter, permease
H0G62_RS18630	COG4174	ABC transporter (Permease)
H0G62_RS18635	COG4166	transmembrane transport
H0G62_RS18660	COG1414	Transcriptional regulator
H0G62_RS18665	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H0G62_RS18670	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H0G62_RS18680	COG1982	Orn Lys Arg decarboxylase major
H0G62_RS18710	COG1063	alcohol dehydrogenase
H0G62_RS18720	COG3284	Transcriptional regulator
H0G62_RS18765	COG2814	Major facilitator Superfamily
H0G62_RS18795	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H0G62_RS18805	COG1215	transferase activity, transferring glycosyl groups
H0G62_RS18825	COG1696	Membrane protein involved in D-alanine export
H0G62_RS18830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H0G62_RS18845	COG1960	acyl-CoA dehydrogenase activity
H0G62_RS18855	COG1301	dicarboxylic acid transport
H0G62_RS18860	COG2198	Histidine kinase
H0G62_RS18860	COG2205	protein histidine kinase activity
H0G62_RS18860	COG0784	Response regulator, receiver
H0G62_RS18895	COG0789	Transcriptional regulator
H0G62_RS18900	COG2217	Heavy metal translocating P-type atpase
H0G62_RS18925	COG2132	Multicopper oxidase
H0G62_RS18930	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
H0G62_RS18950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0G62_RS18960	COG0488	(ABC) transporter
H0G62_RS18980	COG0583	DNA-binding transcription factor activity
H0G62_RS18985	COG1335	isochorismatase
H0G62_RS18990	COG1335	isochorismatase
H0G62_RS19030	COG4968	Prepilin-type N-terminal cleavage methylation domain
H0G62_RS19055	COG0776	regulation of translation
H0G62_RS19065	COG0322	excinuclease ABC activity
H0G62_RS19075	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H0G62_RS19080	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H0G62_RS19085	COG0583	DNA-binding transcription factor activity
H0G62_RS19095	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H0G62_RS19105	COG0534	Mate efflux family protein
H0G62_RS19115	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H0G62_RS19130	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H0G62_RS19305	COG1475	DNA binding
H0G62_RS19340	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
H0G62_RS19360	COG1953	Uracil, thiamine, allantoin
H0G62_RS19375	COG1309	transcriptional regulator
H0G62_RS19380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H0G62_RS19390	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H0G62_RS19400	COG1028	Short-chain dehydrogenase reductase Sdr
H0G62_RS19410	COG0745	RESPONSE REGULATOR receiver
H0G62_RS19415	COG2205	protein histidine kinase activity
H0G62_RS19420	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
H0G62_RS19420	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
H0G62_RS19425	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
H0G62_RS19425	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
H0G62_RS19440	COG0560	Phosphoserine phosphatase
H0G62_RS19450	COG3530	Putative quorum-sensing-regulated virulence factor
H0G62_RS19465	COG1522	sequence-specific DNA binding
H0G62_RS19480	COG0583	DNA-binding transcription factor activity
H0G62_RS19495	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS19500	COG1473	amidohydrolase
H0G62_RS19510	COG2900	Belongs to the SlyX family
H0G62_RS19515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0G62_RS19520	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS19525	COG0154	amidase activity
H0G62_RS19535	COG4804	nuclease activity
H0G62_RS19540	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H0G62_RS19580	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
H0G62_RS19585	COG2186	Transcriptional regulator
H0G62_RS19590	COG0235	Class ii aldolase
H0G62_RS19595	COG2271	Major facilitator Superfamily
H0G62_RS19600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H0G62_RS19605	COG2084	Dehydrogenase
H0G62_RS19630	COG1492	cobalamin metabolic process
H0G62_RS19640	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
H0G62_RS19645	COG0778	Nitroreductase
H0G62_RS19650	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
H0G62_RS19670	COG1737	Transcriptional regulator
H0G62_RS19680	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
H0G62_RS19685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H0G62_RS19690	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
H0G62_RS19700	COG1797	cobyrinic acid a,c-diamide synthase activity
H0G62_RS19715	COG0730	response to heat
H0G62_RS19720	COG5001	Diguanylate cyclase
H0G62_RS19720	COG3300	MHYT domain
H0G62_RS19740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H0G62_RS19755	COG0348	domain, Protein
H0G62_RS19775	COG3278	Belongs to the heme-copper respiratory oxidase family
H0G62_RS19785	COG2217	Heavy metal translocating P-type atpase
H0G62_RS19790	COG0589	response to stress
H0G62_RS19795	COG0318	PFAM AMP-dependent synthetase and ligase
H0G62_RS19800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H0G62_RS19810	COG1024	Enoyl-CoA hydratase
H0G62_RS19840	COG1846	Transcriptional regulator
H0G62_RS19845	COG1960	acyl-CoA dehydrogenase activity
H0G62_RS19860	COG1024	Enoyl-CoA hydratase
H0G62_RS19870	COG0129	dihydroxy-acid dehydratase activity
H0G62_RS19880	COG4654	Cytochrome c, class I
H0G62_RS19890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H0G62_RS19900	COG4175	Glycine betaine
H0G62_RS19905	COG4176	ABC-type proline glycine betaine transport system permease component
H0G62_RS19910	COG2113	Glycine betaine
H0G62_RS19915	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H0G62_RS19915	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H0G62_RS19920	COG1105	Belongs to the carbohydrate kinase PfkB family
H0G62_RS19925	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H0G62_RS19925	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0G62_RS19930	COG1609	Transcriptional regulator
H0G62_RS19955	COG2814	Major facilitator Superfamily
H0G62_RS19965	COG0114	fumarate hydratase activity
H0G62_RS19985	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H0G62_RS19990	COG1451	nucleotide metabolic process
H0G62_RS20010	COG0501	Belongs to the peptidase M48B family
H0G62_RS20040	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H0G62_RS20045	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
H0G62_RS20050	COG0740	serine-type endopeptidase activity
H0G62_RS20055	COG0544	peptidyl-prolyl cis-trans isomerase activity
H0G62_RS20215	COG3550	peptidyl-serine autophosphorylation
H0G62_RS20225	COG0582	viral genome integration into host DNA
H0G62_RS20235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H0G62_RS20240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0G62_RS20250	COG1562	ergosterol biosynthetic process
H0G62_RS20270	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H0G62_RS20295	COG1011	Hydrolase
H0G62_RS20305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H0G62_RS20355	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H0G62_RS20370	COG0583	DNA-binding transcription factor activity
H0G62_RS20385	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H0G62_RS20455	COG4774	siderophore transport
H0G62_RS20460	COG4607	ABC-type enterochelin transport system periplasmic component
H0G62_RS20465	COG4605	iron ion homeostasis
H0G62_RS20470	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H0G62_RS20485	COG3712	iron ion homeostasis
H0G62_RS20490	COG1595	DNA-templated transcription, initiation
H0G62_RS20550	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS20560	COG0642	Histidine kinase
H0G62_RS20565	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H0G62_RS20635	COG0215	cysteine-tRNA ligase activity
H0G62_RS20645	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H0G62_RS20655	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H0G62_RS20690	COG1522	sequence-specific DNA binding
H0G62_RS20705	COG3384	dioxygenase
H0G62_RS20720	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
H0G62_RS20730	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H0G62_RS20770	COG0683	leucine binding
H0G62_RS20775	COG0559	Belongs to the binding-protein-dependent transport system permease family
H0G62_RS20800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H0G62_RS20820	COG0564	pseudouridine synthase activity
H0G62_RS20830	COG1473	amidohydrolase
H0G62_RS20855	COG2918	glutathione biosynthetic process
H0G62_RS20880	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
H0G62_RS20885	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H0G62_RS20890	COG0436	Aminotransferase
H0G62_RS20895	COG0824	Thioesterase
H0G62_RS20915	COG1690	Belongs to the RtcB family
H0G62_RS20920	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
H0G62_RS20950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0G62_RS20955	COG4772	TonB-dependent receptor
H0G62_RS20965	COG0129	dihydroxy-acid dehydratase activity
H0G62_RS20980	COG0348	domain, Protein
H0G62_RS21000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H0G62_RS21005	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS21010	COG1960	acyl-CoA dehydrogenase activity
H0G62_RS21015	COG0583	DNA-binding transcription factor activity
H0G62_RS21020	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H0G62_RS21060	COG4106	trans-aconitate 2-methyltransferase activity
H0G62_RS21065	COG0039	L-malate dehydrogenase activity
H0G62_RS21070	COG2188	Transcriptional regulator
H0G62_RS21075	COG2009	succinate dehydrogenase
H0G62_RS21080	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H0G62_RS21085	COG1053	succinate dehydrogenase
H0G62_RS21090	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H0G62_RS21095	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H0G62_RS21100	COG0372	Belongs to the citrate synthase family
H0G62_RS21115	COG0513	Belongs to the DEAD box helicase family
H0G62_RS21125	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H0G62_RS21135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H0G62_RS21150	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
H0G62_RS21155	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
H0G62_RS21160	COG0583	DNA-binding transcription factor activity
H0G62_RS21170	COG4948	Mandelate Racemase Muconate Lactonizing
H0G62_RS21175	COG0583	DNA-binding transcription factor activity
H0G62_RS21185	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H0G62_RS21205	COG1294	oxidase, subunit
H0G62_RS21215	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H0G62_RS21220	COG4988	ABC transporter
H0G62_RS21230	COG1960	acyl-CoA dehydrogenase activity
H0G62_RS21250	COG1511	domain protein
H0G62_RS21250	COG3264	Mechanosensitive ion channel
H0G62_RS21255	COG1024	Enoyl-CoA hydratase
H0G62_RS21265	COG0714	Associated with various cellular activities
H0G62_RS21280	COG2951	lytic endotransglycosylase activity
H0G62_RS21285	COG0683	leucine binding
H0G62_RS21295	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
H0G62_RS21305	COG3707	response regulator
H0G62_RS21310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H0G62_RS21315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H0G62_RS21320	COG1116	anion transmembrane transporter activity
H0G62_RS21335	COG0840	transmembrane signaling receptor activity
H0G62_RS21340	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0G62_RS21345	COG0243	molybdopterin cofactor binding
H0G62_RS21350	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H0G62_RS21360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0G62_RS21360	COG2205	protein histidine kinase activity
H0G62_RS21365	COG1607	acyl-coa hydrolase
H0G62_RS21370	COG2081	HI0933 family
H0G62_RS21375	COG0828	Belongs to the bacterial ribosomal protein bS21 family
H0G62_RS21385	COG0583	DNA-binding transcription factor activity
H0G62_RS21390	COG0473	3-isopropylmalate dehydrogenase activity
H0G62_RS21410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H0G62_RS21415	COG2271	Major facilitator Superfamily
H0G62_RS21425	COG1309	transcriptional regulator
H0G62_RS21445	COG0633	Ferredoxin
H0G62_RS21480	COG2721	sulfolactate sulfo-lyase activity
H0G62_RS21485	COG1012	belongs to the aldehyde dehydrogenase family
H0G62_RS21535	COG1309	transcriptional regulator
H0G62_RS21560	COG0004	ammonium transporteR
H0G62_RS21570	COG2719	SpoVR family
H0G62_RS21575	COG2718	Belongs to the UPF0229 family
H0G62_RS21580	COG2766	serine protein kinase
H0G62_RS21585	COG1511	domain protein
H0G62_RS21585	COG3264	Mechanosensitive ion channel
H0G62_RS21595	COG0583	DNA-binding transcription factor activity
H0G62_RS21600	COG2301	Belongs to the HpcH HpaI aldolase family
H0G62_RS21605	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H0G62_RS21620	COG0312	modulator of DNA gyrase
H0G62_RS21625	COG3028	Belongs to the UPF0307 family
H0G62_RS21630	COG0521	Mo-molybdopterin cofactor biosynthetic process
H0G62_RS21640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0G62_RS21645	COG1136	(ABC) transporter
H0G62_RS21645	COG0577	efflux transmembrane transporter activity
H0G62_RS21650	COG1538	Outer membrane efflux protein
H0G62_RS21660	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
H0G62_RS21670	COG1045	serine acetyltransferase
H0G62_RS21685	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H0G62_RS21690	COG0640	Transcriptional regulator
H0G62_RS21750	COG1192	Involved in chromosome partitioning
H0G62_RS21760	COG0583	DNA-binding transcription factor activity
H0G62_RS21770	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H0G62_RS21800	COG0431	NADPH-dependent FMN reductase
H0G62_RS21825	COG3712	iron ion homeostasis
H0G62_RS21830	COG1595	DNA-templated transcription, initiation
H0G62_RS21840	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
H0G62_RS21855	COG1968	undecaprenyl-diphosphatase activity
H0G62_RS21885	COG2972	Histidine kinase
H0G62_RS21890	COG3279	Response regulator of the LytR AlgR family
H0G62_RS21910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H0G62_RS21920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0G62_RS21980	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
H0G62_RS21985	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
H0G62_RS21990	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H0G62_RS21995	COG0142	geranyltranstransferase activity
H0G62_RS22000	COG1722	exodeoxyribonuclease VII activity
H0G62_RS22035	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
H0G62_RS22070	COG2353	YceI-like domain
H0G62_RS22125	COG3813	Protein conserved in bacteria
H0G62_RS22140	COG0525	valine-tRNA ligase activity
H0G62_RS22145	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H0G62_RS22150	COG0425	Belongs to the sulfur carrier protein TusA family
H0G62_RS22180	COG1346	cytolysis
H0G62_RS22185	COG0583	DNA-binding transcription factor activity
H0G62_RS22190	COG1960	acyl-CoA dehydrogenase activity
H0G62_RS22195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H0G62_RS22200	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS22205	COG0583	DNA-binding transcription factor activity
H0G62_RS22210	COG0590	tRNA wobble adenosine to inosine editing
H0G62_RS22215	COG2807	transmembrane transport
H0G62_RS22230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H0G62_RS22295	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
H0G62_RS22315	COG0268	Binds directly to 16S ribosomal RNA
H0G62_RS22325	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H0G62_RS22330	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H0G62_RS22350	COG0727	PFAM Uncharacterised protein family (UPF0153)
H0G62_RS22360	COG1113	amino acid transport
H0G62_RS22365	COG1448	Aminotransferase
H0G62_RS22370	COG3483	tryptophan 2,3-dioxygenase activity
H0G62_RS22375	COG0251	oxidation-reduction process
H0G62_RS22385	COG2207	Transcriptional regulator
H0G62_RS22390	COG1113	amino acid transport
H0G62_RS22395	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
H0G62_RS22405	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
H0G62_RS22410	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H0G62_RS22410	COG2169	Transcriptional regulator
H0G62_RS22415	COG3483	tryptophan 2,3-dioxygenase activity
H0G62_RS22425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0G62_RS22435	COG2916	Histone family protein nucleoid-structuring protein H-NS
H0G62_RS22440	COG1253	flavin adenine dinucleotide binding
H0G62_RS22445	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H0G62_RS22450	COG0513	Belongs to the DEAD box helicase family
H0G62_RS22455	COG2321	neutral zinc metallopeptidase
H0G62_RS22465	COG2423	ornithine cyclodeaminase activity
H0G62_RS22480	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H0G62_RS22485	COG0717	Belongs to the dCTP deaminase family
H0G62_RS22490	COG0402	S-adenosylhomocysteine deaminase activity
H0G62_RS22500	COG0537	adenosine 5'-monophosphoramidase activity
H0G62_RS22505	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H0G62_RS22525	COG0745	RESPONSE REGULATOR receiver
H0G62_RS22570	COG5002	protein histidine kinase activity
H0G62_RS22570	COG5001	Diguanylate cyclase
H0G62_RS22570	COG3447	MASE1 domain protein
H0G62_RS22580	COG3300	MHYT domain
H0G62_RS22580	COG5001	Diguanylate cyclase
H0G62_RS22625	COG0405	Gamma-glutamyltransferase
H0G62_RS22630	COG2084	Dehydrogenase
H0G62_RS22635	COG3622	Belongs to the hyi family
H0G62_RS22640	COG3960	tartronate-semialdehyde synthase activity
H0G62_RS22645	COG0583	DNA-binding transcription factor activity
H0G62_RS22665	COG0583	DNA-binding transcription factor activity
H0G62_RS22670	COG2186	Transcriptional regulator
H0G62_RS22690	COG2233	PERMEase
H0G62_RS22695	COG0280	phosphate acetyltransferase
H0G62_RS22695	COG0281	malic enzyme
H0G62_RS22730	COG0583	DNA-binding transcription factor activity
H0G62_RS22745	COG1309	transcriptional regulator
H0G62_RS22775	COG1028	Short-chain dehydrogenase reductase Sdr
H0G62_RS22780	COG1028	Short-chain dehydrogenase reductase Sdr
H0G62_RS22825	COG2885	chlorophyll binding
H0G62_RS22835	COG2274	protein secretion by the type I secretion system
H0G62_RS22840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0G62_RS22870	COG4964	Belongs to the GSP D family
H0G62_RS22920	COG3604	Transcriptional regulator
H0G62_RS22925	COG0438	transferase activity, transferring glycosyl groups
H0G62_RS22940	COG4191	Histidine kinase
H0G62_RS22970	COG0740	serine-type endopeptidase activity
H0G62_RS23025	COG0300	oxidoreductase activity
H0G62_RS23030	COG0789	Transcriptional regulator
H0G62_RS23040	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H0G62_RS23050	COG1609	Transcriptional regulator
H0G62_RS23055	COG1028	Short-chain dehydrogenase reductase Sdr
H0G62_RS23075	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H0G62_RS23080	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H0G62_RS23095	COG1561	YicC-like family, N-terminal region
H0G62_RS23100	COG0194	GDP metabolic process
H0G62_RS23105	COG1758	RNA polymerase activity
H0G62_RS23110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H0G62_RS23120	COG2951	lytic endotransglycosylase activity
H0G62_RS23140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0G62_RS23145	COG1113	amino acid transport
H0G62_RS23195	COG2175	clavaminate synthase activity
H0G62_RS23200	COG3246	L-lysine catabolic process to acetate
H0G62_RS23220	COG3246	L-lysine catabolic process to acetate
H0G62_RS23225	COG2175	clavaminate synthase activity
H0G62_RS23230	COG2207	Transcriptional regulator
H0G62_RS23235	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0G62_RS23240	COG2146	nitrite reductase [NAD(P)H] activity
H0G62_RS23270	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H0G62_RS23285	COG5002	protein histidine kinase activity
H0G62_RS23285	COG5001	Diguanylate cyclase
H0G62_RS23285	COG3447	MASE1 domain protein
H0G62_RS23295	COG1999	signal sequence binding
H0G62_RS23305	COG2267	carboxylic ester hydrolase activity
H0G62_RS23320	COG1414	Transcriptional regulator
H0G62_RS23335	COG2855	membrane
H0G62_RS23365	COG1228	amidohydrolase
H0G62_RS23370	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H0G62_RS23390	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H0G62_RS23455	COG2916	Histone family protein nucleoid-structuring protein H-NS
H0G62_RS23475	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
H0G62_RS23480	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H0G62_RS23480	COG0617	tRNA 3'-terminal CCA addition
H0G62_RS23480	COG0517	IMP dehydrogenase activity
H0G62_RS23485	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
H0G62_RS23490	COG1047	Peptidyl-prolyl cis-trans
H0G62_RS23495	COG2003	Belongs to the UPF0758 family
H0G62_RS23545	COG0583	DNA-binding transcription factor activity
H0G62_RS23555	COG0583	DNA-binding transcription factor activity
H0G62_RS23560	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS23565	COG0697	spore germination
H0G62_RS23570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0G62_RS23580	COG2814	Major facilitator Superfamily
H0G62_RS23590	COG4774	siderophore transport
H0G62_RS23615	COG0745	RESPONSE REGULATOR receiver
H0G62_RS23625	COG2205	protein histidine kinase activity
H0G62_RS23625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0G62_RS23650	COG4829	muconolactone delta-isomerase
H0G62_RS23675	COG0583	DNA-binding transcription factor activity
H0G62_RS23685	COG3383	formate dehydrogenase (NAD+) activity
H0G62_RS23695	COG1846	Transcriptional regulator
H0G62_RS23710	COG0477	Major facilitator Superfamily
H0G62_RS23715	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H0G62_RS23715	COG2010	Cytochrome c
H0G62_RS23720	COG2080	2 iron, 2 sulfur cluster binding
H0G62_RS23730	COG3473	Maleate cis-trans isomerase
H0G62_RS23735	COG0596	Alpha beta hydrolase
H0G62_RS23740	COG2309	aminopeptidase activity
H0G62_RS23745	COG1335	isochorismatase
H0G62_RS23750	COG2010	Cytochrome c
H0G62_RS23750	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H0G62_RS23755	COG0583	DNA-binding transcription factor activity
H0G62_RS23760	COG0489	protein tyrosine kinase activity
H0G62_RS23775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H0G62_RS23775	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H0G62_RS23790	COG3274	enterobacterial common antigen metabolic process
H0G62_RS23830	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
H0G62_RS23845	COG0156	8-amino-7-oxononanoate synthase activity
H0G62_RS23895	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
H0G62_RS23925	COG0583	DNA-binding transcription factor activity
H0G62_RS23935	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
H0G62_RS23940	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
H0G62_RS23945	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H0G62_RS23950	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H0G62_RS23955	COG0588	phosphoglycerate mutase activity
H0G62_RS23960	COG0793	Belongs to the peptidase S41A family
H0G62_RS23975	COG2197	response regulator
H0G62_RS23985	COG5487	UPF0391 membrane protein
H0G62_RS24005	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
H0G62_RS24010	COG0742	ribosomal rna small subunit methyltransferase
H0G62_RS24015	COG0612	Peptidase, M16
H0G62_RS24020	COG0612	Peptidase, M16
H0G62_RS24030	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS24035	COG1324	tolerance protein
H0G62_RS24040	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H0G62_RS24075	COG1012	belongs to the aldehyde dehydrogenase family
H0G62_RS24095	COG1028	Short-chain dehydrogenase reductase Sdr
H0G62_RS24105	COG0300	oxidoreductase activity
H0G62_RS24110	COG3971	2-oxopent-4-enoate hydratase activity
H0G62_RS24115	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0G62_RS24130	COG1464	Belongs to the NlpA lipoprotein family
H0G62_RS24135	COG1464	Belongs to the NlpA lipoprotein family
H0G62_RS24140	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H0G62_RS24145	COG2011	ABC-type metal ion transport system permease component
H0G62_RS24175	COG0431	NADPH-dependent FMN reductase
H0G62_RS24190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H0G62_RS24255	COG2826	transposase and inactivated derivatives, IS30 family
H0G62_RS24350	COG0038	chloride channel
H0G62_RS24385	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H0G62_RS24405	COG1815	bacterial-type flagellum-dependent cell motility
H0G62_RS24410	COG2194	sulfuric ester hydrolase activity
H0G62_RS24440	COG5002	protein histidine kinase activity
H0G62_RS24540	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H0G62_RS24545	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS24560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H0G62_RS24580	COG0840	transmembrane signaling receptor activity
H0G62_RS24585	COG1999	signal sequence binding
H0G62_RS24615	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
H0G62_RS24630	COG2226	methyltransferase
H0G62_RS24635	COG1040	competence protein
H0G62_RS24640	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H0G62_RS24655	COG1280	lysine exporter protein (LysE YggA)
H0G62_RS24685	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H0G62_RS24725	COG1724	mRNA binding
H0G62_RS24780	COG1196	nuclear chromosome segregation
H0G62_RS24985	COG3617	BRO family, N-terminal domain
H0G62_RS25025	COG1487	ribonuclease activity
H0G62_RS25045	COG0625	glutathione transferase activity
H0G62_RS25060	COG0840	transmembrane signaling receptor activity
H0G62_RS25065	COG5001	Diguanylate cyclase
H0G62_RS25065	COG3300	MHYT domain
H0G62_RS25070	COG0642	Histidine kinase
H0G62_RS25075	COG0745	RESPONSE REGULATOR receiver
H0G62_RS25085	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H0G62_RS25090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H0G62_RS25115	COG1178	ABC-type Fe3 transport system permease component
H0G62_RS25120	COG3842	ATPase activity
H0G62_RS25150	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H0G62_RS25155	COG0540	Belongs to the ATCase OTCase family
H0G62_RS25160	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
H0G62_RS25165	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H0G62_RS25170	COG1678	Uncharacterized ACR, COG1678
H0G62_RS25175	COG0415	Belongs to the DNA photolyase family
H0G62_RS25205	COG1773	rubredoxin
H0G62_RS25215	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
H0G62_RS25225	COG2818	Glycosylase
H0G62_RS25235	COG0138	bifunctional purine biosynthesis protein purh
H0G62_RS25240	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H0G62_RS25245	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H0G62_RS25255	COG1238	metal cluster binding
H0G62_RS25260	COG0583	DNA-binding transcription factor activity
H0G62_RS25265	COG1741	Belongs to the pirin family
H0G62_RS25280	COG1574	metal-dependent hydrolase with the TIM-barrel fold
H0G62_RS25295	COG4566	intracellular signal transduction
H0G62_RS25300	COG4191	Histidine kinase
H0G62_RS25315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0G62_RS25325	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS25330	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H0G62_RS25345	COG1028	Short-chain dehydrogenase reductase Sdr
H0G62_RS25350	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS25365	COG4804	nuclease activity
H0G62_RS25380	COG0012	GTP binding
H0G62_RS25385	COG0633	Ferredoxin
H0G62_RS25385	COG3217	Mosc domain protein beta barrel domain protein
H0G62_RS25390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0G62_RS25395	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H0G62_RS25405	COG1024	Enoyl-CoA hydratase
H0G62_RS25440	COG2814	Major facilitator Superfamily
H0G62_RS25470	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H0G62_RS25475	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H0G62_RS25485	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H0G62_RS25510	COG0791	NLP P60 protein
H0G62_RS25515	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H0G62_RS25525	COG5001	Diguanylate cyclase
H0G62_RS25525	COG4251	negative regulation of phosphorylation
H0G62_RS25525	COG2203	Gaf domain
H0G62_RS25525	COG3706	GGDEF domain
H0G62_RS25530	COG4137	Cytochrome C assembly protein
H0G62_RS25555	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H0G62_RS25555	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H0G62_RS25560	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H0G62_RS25570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H0G62_RS25580	COG2264	protein methyltransferase activity
H0G62_RS25585	COG0439	Biotin carboxylase
H0G62_RS25590	COG0511	ligase activity, forming carbon-carbon bonds
H0G62_RS25595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H0G62_RS25605	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H0G62_RS25615	COG3098	single-species biofilm formation
H0G62_RS25620	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H0G62_RS25630	COG0312	modulator of DNA gyrase
H0G62_RS25635	COG0772	Belongs to the SEDS family
H0G62_RS25640	COG3150	esterase
H0G62_RS25645	COG0557	exoribonuclease II activity
H0G62_RS25660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H0G62_RS25665	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
H0G62_RS25675	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H0G62_RS25685	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
H0G62_RS25700	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H0G62_RS25705	COG1181	Belongs to the D-alanine--D-alanine ligase family
H0G62_RS25710	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H0G62_RS25715	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H0G62_RS25720	COG0772	Belongs to the SEDS family
H0G62_RS25725	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H0G62_RS25730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H0G62_RS25735	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H0G62_RS25740	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H0G62_RS25755	COG0275	rRNA processing
H0G62_RS25760	COG2001	Belongs to the MraZ family
H0G62_RS25765	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
H0G62_RS25770	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
H0G62_RS25785	COG0523	cobalamin synthesis protein
H0G62_RS25790	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H0G62_RS25800	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
H0G62_RS25805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H0G62_RS25815	COG3712	iron ion homeostasis
H0G62_RS25830	COG4977	sequence-specific DNA binding
H0G62_RS25865	COG1132	(ABC) transporter
H0G62_RS25870	COG2188	Transcriptional regulator
H0G62_RS25885	COG0114	fumarate hydratase activity
H0G62_RS25895	COG0405	Gamma-glutamyltransferase
H0G62_RS25900	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
H0G62_RS25905	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H0G62_RS25910	COG1473	amidohydrolase
H0G62_RS25970	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H0G62_RS25975	COG1024	Enoyl-CoA hydratase
H0G62_RS25980	COG1960	acyl-CoA dehydrogenase activity
H0G62_RS25985	COG1960	acyl-CoA dehydrogenase activity
H0G62_RS25990	COG0183	Belongs to the thiolase family
H0G62_RS25995	COG1250	3-hydroxyacyl-CoA dehydrogenase
H0G62_RS25995	COG1024	Enoyl-CoA hydratase
H0G62_RS26000	COG0583	DNA-binding transcription factor activity
H0G62_RS26020	COG0501	Belongs to the peptidase M48B family
H0G62_RS26035	COG0418	dihydroorotase activity
H0G62_RS26050	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H0G62_RS26055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H0G62_RS26060	COG0583	DNA-binding transcription factor activity
H0G62_RS26080	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS26105	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS26110	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS26125	COG1126	abc transporter atp-binding protein
H0G62_RS26130	COG0765	amino acid transport
H0G62_RS26135	COG0765	amino acid transport
H0G62_RS26145	COG0583	DNA-binding transcription factor activity
H0G62_RS26150	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H0G62_RS26160	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H0G62_RS26175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H0G62_RS26215	COG5265	(ABC) transporter
H0G62_RS26220	COG1607	acyl-coa hydrolase
H0G62_RS26245	COG1024	Enoyl-CoA hydratase
H0G62_RS26260	COG0183	Belongs to the thiolase family
H0G62_RS26265	COG1024	Enoyl-CoA hydratase
H0G62_RS26265	COG1250	3-hydroxyacyl-CoA dehydrogenase
H0G62_RS26275	COG1960	acyl-CoA dehydrogenase activity
H0G62_RS26320	COG3451	type IV secretory pathway VirB4
H0G62_RS26330	COG3838	Conjugal transfer protein Trbc
H0G62_RS26335	COG4962	Type ii secretion system protein e
H0G62_RS26355	COG0583	DNA-binding transcription factor activity
H0G62_RS26400	COG2132	Multicopper oxidase
H0G62_RS26405	COG0745	RESPONSE REGULATOR receiver
H0G62_RS26435	COG1192	Involved in chromosome partitioning
H0G62_RS26460	COG1396	sequence-specific DNA binding
H0G62_RS26465	COG5489	Protein of unknown function (DUF736)
H0G62_RS26490	COG1475	DNA binding
H0G62_RS26530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0G62_RS26565	COG1968	undecaprenyl-diphosphatase activity
H0G62_RS26595	COG0640	Transcriptional regulator
H0G62_RS26610	COG0798	PFAM Bile acid sodium symporter
H0G62_RS26620	COG0431	NADPH-dependent FMN reductase
H0G62_RS26650	COG1309	transcriptional regulator
H0G62_RS26660	COG0745	RESPONSE REGULATOR receiver
H0G62_RS26665	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H0G62_RS26680	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H0G62_RS26710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H0G62_RS26770	COG1459	type II secretion system
H0G62_RS26775	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H0G62_RS26780	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
H0G62_RS26785	COG1652	LysM domain
H0G62_RS26795	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS26800	COG0583	DNA-binding transcription factor activity
H0G62_RS26820	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H0G62_RS26825	COG0751	glycine-tRNA ligase activity
H0G62_RS26830	COG0752	glycyl-tRNA synthetase alpha subunit
H0G62_RS26835	COG4260	virion core protein, lumpy skin disease virus
H0G62_RS26855	COG3842	ATPase activity
H0G62_RS26860	COG1840	ABC-type Fe3 transport system, periplasmic component
H0G62_RS26865	COG2186	Transcriptional regulator
H0G62_RS26870	COG1953	Uracil, thiamine, allantoin
H0G62_RS26875	COG0583	DNA-binding transcription factor activity
H0G62_RS26915	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H0G62_RS26920	COG0815	Transfers the fatty acyl group on membrane lipoproteins
H0G62_RS26935	COG1522	sequence-specific DNA binding
H0G62_RS26945	COG3186	Phenylalanine-4-hydroxylase
H0G62_RS26955	COG0318	PFAM AMP-dependent synthetase and ligase
H0G62_RS26965	COG4774	siderophore transport
H0G62_RS26970	COG4774	siderophore transport
H0G62_RS26975	COG3128	pkhd-type hydroxylase
H0G62_RS26990	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H0G62_RS26995	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H0G62_RS27015	COG5002	protein histidine kinase activity
H0G62_RS27055	COG0037	tRNA processing
H0G62_RS27080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H0G62_RS27085	COG0601	transmembrane transport
H0G62_RS27155	COG2255	four-way junction helicase activity
H0G62_RS27160	COG0632	four-way junction helicase activity
H0G62_RS27165	COG1702	phosphate starvation-inducible protein PhoH
H0G62_RS27170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H0G62_RS27175	COG0604	alcohol dehydrogenase
H0G62_RS27190	COG0583	DNA-binding transcription factor activity
H0G62_RS27195	COG0730	response to heat
H0G62_RS27245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H0G62_RS27250	COG1490	D-aminoacyl-tRNA deacylase activity
H0G62_RS27255	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H0G62_RS27260	COG4191	Histidine kinase
H0G62_RS27265	COG4566	intracellular signal transduction
H0G62_RS27280	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H0G62_RS27295	COG1250	3-hydroxyacyl-CoA dehydrogenase
H0G62_RS27305	COG1846	Transcriptional regulator
H0G62_RS27310	COG1764	response to oxidative stress
H0G62_RS27350	COG2814	Major facilitator Superfamily
H0G62_RS27360	COG0831	urea catabolic process
H0G62_RS27370	COG0832	Belongs to the urease beta subunit family
H0G62_RS27375	COG0804	urea catabolic process
H0G62_RS27385	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
H0G62_RS27390	COG0830	nickel cation binding
H0G62_RS27395	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
H0G62_RS27415	COG0326	Molecular chaperone. Has ATPase activity
H0G62_RS27420	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H0G62_RS27425	COG4774	siderophore transport
H0G62_RS27430	COG3128	pkhd-type hydroxylase
H0G62_RS27440	COG3712	iron ion homeostasis
H0G62_RS27445	COG1595	DNA-templated transcription, initiation
H0G62_RS27450	COG1187	pseudouridine synthase activity
H0G62_RS27475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H0G62_RS27490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H0G62_RS27495	COG1022	Amp-dependent synthetase and ligase
H0G62_RS27505	COG0559	Belongs to the binding-protein-dependent transport system permease family
H0G62_RS27545	COG0667	Aldo Keto reductase
H0G62_RS27555	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H0G62_RS27570	COG0642	Histidine kinase
H0G62_RS27575	COG0745	RESPONSE REGULATOR receiver
H0G62_RS27590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H0G62_RS27595	COG1116	anion transmembrane transporter activity
H0G62_RS27625	COG3842	ATPase activity
H0G62_RS27630	COG1473	amidohydrolase
H0G62_RS27640	COG0243	molybdopterin cofactor binding
H0G62_RS27680	COG2814	Major facilitator Superfamily
H0G62_RS27685	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H0G62_RS27695	COG0277	FAD linked oxidase domain protein
H0G62_RS27700	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
H0G62_RS27710	COG3945	hemerythrin HHE cation binding domain
H0G62_RS27720	COG0288	reversible hydration of carbon dioxide
H0G62_RS27725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H0G62_RS27730	COG2181	nitrate reductase activity
H0G62_RS27735	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
H0G62_RS27740	COG1140	nitrate reductase beta subunit
H0G62_RS27745	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H0G62_RS27750	COG2223	nitrite transmembrane transporter activity
H0G62_RS27780	COG2197	response regulator
H0G62_RS27785	COG4585	Histidine kinase
H0G62_RS27800	COG2733	membrane
H0G62_RS27810	COG4771	TonB-dependent receptor
H0G62_RS27825	COG2204	response regulator
H0G62_RS27830	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H0G62_RS27845	COG0439	Biotin carboxylase
H0G62_RS27850	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
H0G62_RS27865	COG5002	protein histidine kinase activity
H0G62_RS27895	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H0G62_RS27920	COG0277	FAD linked oxidase domain protein
H0G62_RS27925	COG0583	DNA-binding transcription factor activity
H0G62_RS27955	COG0545	Peptidyl-prolyl cis-trans isomerase
H0G62_RS27965	COG4770	biotin carboxylase activity
H0G62_RS27970	COG0318	PFAM AMP-dependent synthetase and ligase
H0G62_RS27985	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H0G62_RS27995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H0G62_RS28005	COG2084	Dehydrogenase
H0G62_RS28010	COG2823	Periplasmic or secreted lipoprotein
H0G62_RS28015	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
H0G62_RS28020	COG0792	nuclease activity
H0G62_RS28030	COG0443	Heat shock 70 kDa protein
H0G62_RS28060	COG4172	Belongs to the ABC transporter superfamily
H0G62_RS28065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H0G62_RS28080	COG0471	metal ion transport
H0G62_RS28095	COG0203	ribosomal protein L17
H0G62_RS28100	COG0202	RNA polymerase activity
H0G62_RS28105	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
H0G62_RS28110	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
H0G62_RS28115	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H0G62_RS28120	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H0G62_RS28125	COG0201	protein transport
H0G62_RS28130	COG0200	Binds to the 23S rRNA
H0G62_RS28135	COG1841	ribosomal large subunit assembly
H0G62_RS28140	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
H0G62_RS28145	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
H0G62_RS28150	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
H0G62_RS28155	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
H0G62_RS28160	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H0G62_RS28165	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H0G62_RS28170	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
H0G62_RS28175	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
H0G62_RS28185	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H0G62_RS28200	COG0395	ABC-type sugar transport system, permease component
H0G62_RS28210	COG3842	ATPase activity
H0G62_RS28215	COG3842	ATPase activity
H0G62_RS28225	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H0G62_RS28240	COG0028	Belongs to the TPP enzyme family
H0G62_RS28260	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H0G62_RS28265	COG0671	phosphoesterase, PA-phosphatase related
H0G62_RS28270	COG0783	Belongs to the Dps family
H0G62_RS28285	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H0G62_RS28295	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
H0G62_RS28300	COG4604	ABC transporter, ATP-binding protein
H0G62_RS28305	COG4605	iron ion homeostasis
H0G62_RS28310	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H0G62_RS28315	COG4607	ABC-type enterochelin transport system periplasmic component
H0G62_RS28330	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
H0G62_RS28340	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H0G62_RS28345	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H0G62_RS28350	COG0693	protein deglycase activity
H0G62_RS28365	COG0583	DNA-binding transcription factor activity
H0G62_RS28375	COG3118	belongs to the thioredoxin family
H0G62_RS28390	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H0G62_RS28395	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H0G62_RS28400	COG0009	L-threonylcarbamoyladenylate synthase
H0G62_RS28415	COG3718	enzyme involved in inositol metabolism
H0G62_RS28455	COG1214	PFAM Peptidase M22, glycoprotease
H0G62_RS28460	COG0456	acetyltransferase
H0G62_RS28470	COG0598	Magnesium transport protein CorA
H0G62_RS28475	COG0251	oxidation-reduction process
H0G62_RS28490	COG0583	DNA-binding transcription factor activity
H0G62_RS28530	COG1012	belongs to the aldehyde dehydrogenase family
H0G62_RS28540	COG1028	Short-chain dehydrogenase reductase Sdr
H0G62_RS28545	COG1414	Transcriptional regulator
H0G62_RS28565	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
H0G62_RS28570	COG1414	Transcriptional regulator
H0G62_RS28590	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H0G62_RS28595	COG1309	transcriptional regulator
H0G62_RS28600	COG1522	sequence-specific DNA binding
H0G62_RS28615	COG0656	L-ascorbic acid biosynthetic process
H0G62_RS28620	COG0583	DNA-binding transcription factor activity
H0G62_RS28625	COG1473	amidohydrolase
H0G62_RS28630	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS28635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H0G62_RS28645	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H0G62_RS28650	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H0G62_RS28655	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H0G62_RS28675	COG0745	RESPONSE REGULATOR receiver
H0G62_RS28685	COG0671	phosphoesterase, PA-phosphatase related
H0G62_RS28690	COG0469	pyruvate kinase activity
H0G62_RS28700	COG0318	PFAM AMP-dependent synthetase and ligase
H0G62_RS28715	COG0006	proline dipeptidase activity
H0G62_RS28720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H0G62_RS28725	COG0640	Transcriptional regulator
H0G62_RS28755	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H0G62_RS28760	COG0583	DNA-binding transcription factor activity
H0G62_RS28780	COG0583	DNA-binding transcription factor activity
H0G62_RS28785	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS28790	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H0G62_RS28805	COG0625	glutathione transferase activity
H0G62_RS28820	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H0G62_RS28825	COG3550	peptidyl-serine autophosphorylation
H0G62_RS28835	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H0G62_RS28835	COG2755	lipolytic protein G-D-S-L family
H0G62_RS28855	COG0420	3'-5' exonuclease activity
H0G62_RS28860	COG0419	ATPase involved in DNA repair
H0G62_RS28885	COG0386	Belongs to the glutathione peroxidase family
H0G62_RS28895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H0G62_RS28900	COG2365	Tyrosine phosphatase family
H0G62_RS28940	COG0642	Histidine kinase
H0G62_RS28945	COG0745	RESPONSE REGULATOR receiver
H0G62_RS28955	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
H0G62_RS28960	COG2137	regulation of response to DNA damage stimulus
H0G62_RS28980	COG0045	succinate-CoA ligase (ADP-forming) activity
H0G62_RS28985	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H0G62_RS28990	COG0861	Integral membrane protein TerC family
H0G62_RS29015	COG0315	cyclic pyranopterin monophosphate synthase activity
H0G62_RS29020	COG4783	chaperone-mediated protein folding
H0G62_RS29025	COG1950	PFAM Membrane protein of
H0G62_RS29035	COG0861	Integral membrane protein TerC family
H0G62_RS29070	COG0625	glutathione transferase activity
H0G62_RS29110	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
H0G62_RS29115	COG2814	Major facilitator Superfamily
H0G62_RS29120	COG1522	sequence-specific DNA binding
H0G62_RS29130	COG1862	Preprotein translocase
H0G62_RS29135	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H0G62_RS29140	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H0G62_RS29150	COG0758	DNA mediated transformation
H0G62_RS29160	COG0242	peptide deformylase activity
H0G62_RS29170	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H0G62_RS29185	COG0126	phosphoglycerate kinase activity
H0G62_RS29205	COG0284	orotidine-5'-phosphate decarboxylase activity
H0G62_RS29210	COG0583	DNA-binding transcription factor activity
H0G62_RS29235	COG2814	Major facilitator Superfamily
H0G62_RS29240	COG0629	single-stranded DNA binding
H0G62_RS29255	COG0659	secondary active sulfate transmembrane transporter activity
H0G62_RS29270	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0G62_RS29275	COG2151	metal-sulfur cluster biosynthetic enzyme
H0G62_RS29280	COG3396	Phenylacetate-CoA oxygenase
H0G62_RS29285	COG3460	Phenylacetate-CoA oxygenase
H0G62_RS29290	COG3396	Phenylacetate-CoA oxygenase
H0G62_RS29300	COG1012	belongs to the aldehyde dehydrogenase family
H0G62_RS29305	COG1309	transcriptional regulator
H0G62_RS29315	COG4585	Histidine kinase
H0G62_RS29325	COG0482	sulfurtransferase activity
H0G62_RS29330	COG0583	DNA-binding transcription factor activity
H0G62_RS29335	COG1024	Enoyl-CoA hydratase
H0G62_RS29345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H0G62_RS29375	COG1053	succinate dehydrogenase
H0G62_RS29375	COG3976	FMN-binding domain protein
H0G62_RS29425	COG1129	ABC transporter
H0G62_RS29435	COG1172	Belongs to the binding-protein-dependent transport system permease family
H0G62_RS29445	COG1072	(Pantothenic acid kinase))
H0G62_RS29470	COG0583	DNA-binding transcription factor activity
H0G62_RS29495	COG2015	COG2015, Alkyl sulfatase and related hydrolases
H0G62_RS29500	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
H0G62_RS29515	COG0134	indole-3-glycerol-phosphate synthase activity
H0G62_RS29520	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H0G62_RS29560	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H0G62_RS29570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0G62_RS29575	COG0842	Transport permease protein
H0G62_RS29575	COG1129	ABC transporter
H0G62_RS29580	COG0842	Transport permease protein
H0G62_RS29625	COG3621	Patatin-like phospholipase
H0G62_RS29640	COG0642	Histidine kinase
H0G62_RS29665	COG0546	phosphoglycolate phosphatase activity
H0G62_RS29670	COG0840	transmembrane signaling receptor activity
H0G62_RS29675	COG0835	chemotaxis
H0G62_RS29680	COG0840	transmembrane signaling receptor activity
H0G62_RS29690	COG0745	RESPONSE REGULATOR receiver
H0G62_RS29695	COG3437	response regulator, receiver
H0G62_RS29695	COG0784	Response regulator, receiver
H0G62_RS29700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0G62_RS29705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0G62_RS29705	COG2205	protein histidine kinase activity
H0G62_RS29715	COG0583	DNA-binding transcription factor activity
H0G62_RS29720	COG1028	Short-chain dehydrogenase reductase Sdr
H0G62_RS29725	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H0G62_RS29735	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H0G62_RS29740	COG3959	Transketolase, thiamine diphosphate binding domain
H0G62_RS29745	COG3958	Transketolase
H0G62_RS29775	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H0G62_RS29780	COG2967	ApaG domain
H0G62_RS29795	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
H0G62_RS29820	COG0583	DNA-binding transcription factor activity
H0G62_RS29835	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H0G62_RS29840	COG1546	Belongs to the CinA family
H0G62_RS29850	COG0653	protein targeting
H0G62_RS29855	COG1960	acyl-CoA dehydrogenase activity
H0G62_RS29865	COG0183	Belongs to the thiolase family
H0G62_RS29880	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H0G62_RS29910	COG0456	acetyltransferase
H0G62_RS29930	COG2076	Multidrug Resistance protein
H0G62_RS29945	COG2423	ornithine cyclodeaminase activity
H0G62_RS29950	COG0010	Belongs to the arginase family
H0G62_RS29960	COG3541	Predicted nucleotidyltransferase
H0G62_RS29965	COG1690	Belongs to the RtcB family
H0G62_RS29980	COG4650	regulator
H0G62_RS29985	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H0G62_RS29990	COG1137	ATPase activity
H0G62_RS29995	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H0G62_RS30000	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H0G62_RS30005	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H0G62_RS30010	COG0018	arginyl-trna synthetase
H0G62_RS30030	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H0G62_RS30040	COG1942	4-Oxalocrotonate Tautomerase
H0G62_RS30050	COG0121	glutamine amidotransferase
H0G62_RS30110	COG0189	ligase activity
H0G62_RS30115	COG3135	benzoate transporter
H0G62_RS30120	COG3158	transport of potassium into the cell
H0G62_RS30130	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H0G62_RS30135	COG0569	domain protein
H0G62_RS30140	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H0G62_RS30165	COG0668	transmembrane transport
H0G62_RS30185	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H0G62_RS30190	COG0735	belongs to the Fur family
H0G62_RS30205	COG1595	DNA-templated transcription, initiation
H0G62_RS30220	COG3437	response regulator, receiver
H0G62_RS30225	COG0784	Response regulator, receiver
H0G62_RS30225	COG2198	Histidine kinase
H0G62_RS30225	COG2205	protein histidine kinase activity
H0G62_RS30245	COG3181	Tripartite tricarboxylate transporter family receptor
H0G62_RS30260	COG0559	Belongs to the binding-protein-dependent transport system permease family
H0G62_RS30265	COG4177	L-phenylalanine transmembrane transporter activity
H0G62_RS30290	COG0280	phosphate acetyltransferase
H0G62_RS30290	COG0281	malic enzyme
H0G62_RS30305	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H0G62_RS30310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H0G62_RS30315	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
H0G62_RS30325	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H0G62_RS30345	COG2249	NAD(P)H dehydrogenase (quinone) activity
H0G62_RS30350	COG0584	glycerophosphoryl diester phosphodiesterase
H0G62_RS30355	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H0G62_RS30355	COG2813	Specifically methylates the guanine in position
H0G62_RS30360	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H0G62_RS30365	COG2119	membrane
H0G62_RS30370	COG0724	RNA recognition motif
H0G62_RS30375	COG0724	RNA recognition motif
H0G62_RS30380	COG0300	oxidoreductase activity
H0G62_RS30395	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H0G62_RS30395	COG0517	IMP dehydrogenase activity
H0G62_RS30400	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H0G62_RS30420	COG0706	membrane insertase activity
H0G62_RS30425	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
H0G62_RS30435	COG0230	Belongs to the bacterial ribosomal protein bL34 family