locus-tag	class	description
FOB48_RS00010	COG0395	ABC-type sugar transport system, permease component
FOB48_RS00025	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOB48_RS00035	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB48_RS00040	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB48_RS00045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOB48_RS00050	COG1653	transport
FOB48_RS00055	COG1175	transmembrane transport
FOB48_RS00060	COG0395	ABC-type sugar transport system, permease component
FOB48_RS00065	COG4868	Belongs to the UPF0371 family
FOB48_RS00145	COG1464	Belongs to the NlpA lipoprotein family
FOB48_RS00150	COG2011	ABC-type metal ion transport system permease component
FOB48_RS00155	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOB48_RS00170	COG0590	tRNA wobble adenosine to inosine editing
FOB48_RS00175	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FOB48_RS00190	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOB48_RS00220	COG0305	Participates in initiation and elongation during chromosome replication
FOB48_RS00300	COG1482	cell wall glycoprotein biosynthetic process
FOB48_RS00305	COG0583	DNA-binding transcription factor activity
FOB48_RS00330	COG1132	(ABC) transporter
FOB48_RS00335	COG1132	(ABC) transporter
FOB48_RS00340	COG1929	Belongs to the glycerate kinase type-1 family
FOB48_RS00350	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FOB48_RS00355	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FOB48_RS00365	COG0656	L-ascorbic acid biosynthetic process
FOB48_RS00370	COG0656	L-ascorbic acid biosynthetic process
FOB48_RS00400	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOB48_RS00410	COG4977	sequence-specific DNA binding
FOB48_RS00430	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOB48_RS00445	COG1074	ATP-dependent DNA helicase activity
FOB48_RS00460	COG1674	ftsk spoiiie
FOB48_RS00555	COG0366	Alpha amylase catalytic
FOB48_RS00560	COG2376	Dihydroxyacetone kinase
FOB48_RS00565	COG0395	ABC-type sugar transport system, permease component
FOB48_RS00570	COG1175	transmembrane transport
FOB48_RS00580	COG1940	carbohydrate kinase activity
FOB48_RS00590	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOB48_RS00620	COG0402	S-adenosylhomocysteine deaminase activity
FOB48_RS00625	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FOB48_RS00650	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FOB48_RS00655	COG1012	belongs to the aldehyde dehydrogenase family
FOB48_RS00665	COG2186	Transcriptional regulator
FOB48_RS00680	COG1136	(ABC) transporter
FOB48_RS00720	COG5564	TIM-barrel signal transduction protein
FOB48_RS00725	COG1715	Restriction endonuclease
FOB48_RS00745	COG1002	Type II restriction enzyme, methylase subunits
FOB48_RS00750	COG0798	PFAM Bile acid sodium symporter
FOB48_RS00755	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOB48_RS00780	COG5646	InterPro IPR014922
FOB48_RS00790	COG4552	Acetyltransferase involved in intracellular survival and related
FOB48_RS00820	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
FOB48_RS00840	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOB48_RS00845	COG0187	DNA topoisomerase II activity
FOB48_RS00855	COG0737	Belongs to the 5'-nucleotidase family
FOB48_RS00860	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
FOB48_RS00865	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FOB48_RS00870	COG0592	DNA-directed DNA polymerase activity
FOB48_RS00875	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOB48_RS00880	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FOB48_RS00885	COG0594	ribonuclease P activity
FOB48_RS00890	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FOB48_RS00895	COG0706	membrane insertase activity
FOB48_RS00905	COG0357	Ribosomal RNA small subunit methyltransferase G
FOB48_RS00910	COG1192	Involved in chromosome partitioning
FOB48_RS00920	COG0492	ferredoxin-NADP+ reductase activity
FOB48_RS00945	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOB48_RS00950	COG0360	Binds together with S18 to 16S ribosomal RNA
FOB48_RS00960	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FOB48_RS00965	COG0359	binds to the 23S rRNA
FOB48_RS00970	COG1113	amino acid transport
FOB48_RS01000	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FOB48_RS01015	COG0326	Molecular chaperone. Has ATPase activity
FOB48_RS01030	COG1309	transcriptional regulator
FOB48_RS01050	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FOB48_RS01055	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOB48_RS01055	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FOB48_RS01070	COG0431	NADPH-dependent FMN reductase
FOB48_RS01090	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOB48_RS01095	COG0730	response to heat
FOB48_RS01100	COG1757	Na H antiporter
FOB48_RS01115	COG1129	ABC transporter
FOB48_RS01120	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB48_RS01145	COG1132	(ABC) transporter
FOB48_RS01155	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOB48_RS01160	COG1121	(ABC) transporter
FOB48_RS01185	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FOB48_RS01190	COG0010	Belongs to the arginase family
FOB48_RS01200	COG0028	Belongs to the TPP enzyme family
FOB48_RS01220	COG1918	ferrous iron import across plasma membrane
FOB48_RS01230	COG0316	Belongs to the HesB IscA family
FOB48_RS01230	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FOB48_RS01245	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOB48_RS01250	COG1086	Polysaccharide biosynthesis protein
FOB48_RS01255	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FOB48_RS01265	COG2089	acid synthase
FOB48_RS01275	COG0438	transferase activity, transferring glycosyl groups
FOB48_RS01280	COG0463	Glycosyl transferase, family 2
FOB48_RS01290	COG1134	teichoic acid transport
FOB48_RS01295	COG2197	response regulator
FOB48_RS01300	COG4585	Histidine kinase
FOB48_RS01320	COG4720	Psort location CytoplasmicMembrane, score
FOB48_RS01325	COG1122	ATPase activity
FOB48_RS01330	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOB48_RS01345	COG0259	pyridoxamine-phosphate oxidase activity
FOB48_RS01360	COG1131	(ABC) transporter
FOB48_RS01385	COG5504	Zn-dependent protease
FOB48_RS01395	COG0252	asparaginase activity
FOB48_RS01400	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOB48_RS01405	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FOB48_RS01410	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOB48_RS01440	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FOB48_RS01450	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
FOB48_RS01465	COG0463	Glycosyl transferase, family 2
FOB48_RS01470	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOB48_RS01475	COG0656	L-ascorbic acid biosynthetic process
FOB48_RS01485	COG0386	Belongs to the glutathione peroxidase family
FOB48_RS01495	COG0561	phosphatase activity
FOB48_RS01525	COG0018	arginyl-trna synthetase
FOB48_RS01540	COG2801	Transposase and inactivated derivatives
FOB48_RS01605	COG0077	Prephenate dehydratase
FOB48_RS01615	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FOB48_RS01620	COG0561	phosphatase activity
FOB48_RS01670	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FOB48_RS01675	COG2116	formate transmembrane transporter activity
FOB48_RS01685	COG4221	oxidoreductase activity
FOB48_RS01715	COG2755	lipolytic protein G-D-S-L family
FOB48_RS01725	COG3764	Sortase (surface protein transpeptidase)
FOB48_RS01735	COG0515	serine threonine protein kinase
FOB48_RS01740	COG0515	serine threonine protein kinase
FOB48_RS01745	COG0768	penicillin binding
FOB48_RS01760	COG1716	ATPase activity
FOB48_RS01780	COG0438	transferase activity, transferring glycosyl groups
FOB48_RS01780	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOB48_RS01790	COG3883	PFAM NLP P60 protein
FOB48_RS01790	COG0791	NLP P60 protein
FOB48_RS01800	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FOB48_RS01805	COG0113	porphobilinogen synthase activity
FOB48_RS01815	COG0181	hydroxymethylbilane synthase activity
FOB48_RS01820	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FOB48_RS01825	COG3253	May function as heme-dependent peroxidase
FOB48_RS01830	COG1231	oxidoreductase activity
FOB48_RS01835	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FOB48_RS01840	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FOB48_RS01850	COG2755	lipolytic protein G-D-S-L family
FOB48_RS01850	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FOB48_RS01855	COG1362	aminopeptidase activity
FOB48_RS01860	COG1216	Glycosyl transferase, family 2
FOB48_RS01865	COG1215	transferase activity, transferring glycosyl groups
FOB48_RS01885	COG2755	lipolytic protein G-D-S-L family
FOB48_RS01885	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FOB48_RS01890	COG0343	queuine tRNA-ribosyltransferase activity
FOB48_RS01935	COG3281	Trehalose synthase
FOB48_RS01945	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FOB48_RS01960	COG1408	metallophosphoesterase
FOB48_RS01965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOB48_RS02000	COG1278	Cold shock
FOB48_RS02015	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FOB48_RS02025	COG1754	DNA topoisomerase type I activity
FOB48_RS02025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOB48_RS02030	COG2890	protein-(glutamine-N5) methyltransferase activity
FOB48_RS02035	COG1111	helicase
FOB48_RS02035	COG1205	dead DEAH box helicase
FOB48_RS02080	COG1028	Short-chain dehydrogenase reductase Sdr
FOB48_RS02090	COG1022	Amp-dependent synthetase and ligase
FOB48_RS02095	COG0586	Pfam SNARE associated Golgi protein
FOB48_RS02105	COG1064	alcohol dehydrogenase
FOB48_RS02110	COG2197	response regulator
FOB48_RS02115	COG4585	Histidine kinase
FOB48_RS02135	COG0534	Mate efflux family protein
FOB48_RS02140	COG1846	Transcriptional regulator
FOB48_RS02160	COG0354	folic acid binding
FOB48_RS02195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOB48_RS02215	COG4221	oxidoreductase activity
FOB48_RS02225	COG1937	Protein conserved in bacteria
FOB48_RS02230	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOB48_RS02245	COG0022	dehydrogenase e1 component
FOB48_RS02250	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOB48_RS02260	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOB48_RS02295	COG1609	Transcriptional regulator
FOB48_RS02315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB48_RS02320	COG0488	(ABC) transporter
FOB48_RS02330	COG2801	Transposase and inactivated derivatives
FOB48_RS02330	COG3415	Transposase
FOB48_RS02340	COG4585	Histidine kinase
FOB48_RS02415	COG3415	Transposase
FOB48_RS02415	COG2801	Transposase and inactivated derivatives
FOB48_RS02425	COG0717	Belongs to the dCTP deaminase family
FOB48_RS02440	COG2111	Na H antiporter
FOB48_RS02440	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOB48_RS02445	COG1006	Multisubunit Na H antiporter MnhC subunit
FOB48_RS02450	COG0651	ATP synthesis coupled electron transport
FOB48_RS02460	COG2212	antiporter activity
FOB48_RS02470	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FOB48_RS02485	COG1643	Atp-dependent helicase
FOB48_RS02490	COG1268	BioY protein
FOB48_RS02590	COG1780	Probably involved in ribonucleotide reductase function
FOB48_RS02595	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOB48_RS02605	COG3833	ABC-type maltose transport systems, permease component
FOB48_RS02610	COG1175	transmembrane transport
FOB48_RS02615	COG1653	transport
FOB48_RS02620	COG1609	Transcriptional regulator
FOB48_RS02635	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOB48_RS02645	COG1472	Belongs to the glycosyl hydrolase 3 family
FOB48_RS02670	COG1609	Transcriptional regulator
FOB48_RS02680	COG1175	transmembrane transport
FOB48_RS02695	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOB48_RS02705	COG1205	dead DEAH box helicase
FOB48_RS02705	COG1111	helicase
FOB48_RS02710	COG0210	DNA helicase
FOB48_RS02725	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FOB48_RS02730	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FOB48_RS02735	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FOB48_RS02760	COG0512	Glutamine amidotransferase of anthranilate synthase
FOB48_RS02760	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOB48_RS02770	COG1739	Uncharacterized protein family UPF0029
FOB48_RS02780	COG1316	TRANSCRIPTIONal
FOB48_RS02825	COG0745	RESPONSE REGULATOR receiver
FOB48_RS02830	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FOB48_RS02860	COG0681	Belongs to the peptidase S26 family
FOB48_RS02895	COG1131	(ABC) transporter
FOB48_RS02910	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOB48_RS02915	COG0366	Alpha amylase catalytic
FOB48_RS02920	COG0740	serine-type endopeptidase activity
FOB48_RS02925	COG0740	serine-type endopeptidase activity
FOB48_RS02930	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FOB48_RS02935	COG0287	Prephenate dehydrogenase
FOB48_RS02935	COG1605	Chorismate mutase
FOB48_RS02970	COG0525	valine-tRNA ligase activity
FOB48_RS02995	COG2197	response regulator
FOB48_RS03015	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOB48_RS03025	COG0285	dihydrofolate synthase activity
FOB48_RS03035	COG0105	UTP biosynthetic process
FOB48_RS03045	COG0552	protein localization to endoplasmic reticulum
FOB48_RS03060	COG0228	four-way junction DNA binding
FOB48_RS03065	COG1837	Belongs to the UPF0109 family
FOB48_RS03075	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FOB48_RS03080	COG0336	Belongs to the RNA methyltransferase TrmD family
FOB48_RS03090	COG0335	large ribosomal subunit rRNA binding
FOB48_RS03105	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FOB48_RS03135	COG2814	Major facilitator Superfamily
FOB48_RS03145	COG4974	Belongs to the 'phage' integrase family
FOB48_RS03155	COG0052	Belongs to the universal ribosomal protein uS2 family
FOB48_RS03160	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FOB48_RS03165	COG0528	UMP kinase activity
FOB48_RS03170	COG0233	cytoplasmic translational termination
FOB48_RS03180	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FOB48_RS03190	COG0750	zinc metalloprotease
FOB48_RS03200	COG2357	RelA SpoT domain protein
FOB48_RS03205	COG0442	prolyl-tRNA aminoacylation
FOB48_RS03215	COG0779	Required for maturation of 30S ribosomal subunits
FOB48_RS03230	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FOB48_RS03230	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FOB48_RS03240	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FOB48_RS03245	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOB48_RS03265	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FOB48_RS03270	COG1185	polyribonucleotide nucleotidyltransferase activity
FOB48_RS03280	COG0612	Peptidase, M16
FOB48_RS03285	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FOB48_RS03305	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FOB48_RS03310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOB48_RS03315	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOB48_RS03320	COG1674	ftsk spoiiie
FOB48_RS03330	COG1546	Belongs to the CinA family
FOB48_RS03330	COG1058	Belongs to the CinA family
FOB48_RS03345	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FOB48_RS03350	COG2137	regulation of response to DNA damage stimulus
FOB48_RS03355	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOB48_RS03365	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FOB48_RS03370	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FOB48_RS03375	COG2813	Specifically methylates the guanine in position
FOB48_RS03380	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOB48_RS03390	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FOB48_RS03400	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FOB48_RS03410	COG1278	Cold shock
FOB48_RS03425	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOB48_RS03435	COG2001	Belongs to the MraZ family
FOB48_RS03450	COG0768	penicillin binding
FOB48_RS03455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOB48_RS03460	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOB48_RS03465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOB48_RS03470	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FOB48_RS03480	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOB48_RS03485	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOB48_RS03495	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOB48_RS03500	COG1496	oxidoreductase activity
FOB48_RS03505	COG1799	cell septum assembly
FOB48_RS03520	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FOB48_RS03530	COG0587	DNA-directed DNA polymerase activity
FOB48_RS03550	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FOB48_RS03585	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOB48_RS03590	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FOB48_RS03595	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FOB48_RS03600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOB48_RS03605	COG1276	copper resistance
FOB48_RS03610	COG1486	melibiose metabolic process
FOB48_RS03615	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FOB48_RS03615	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FOB48_RS03630	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FOB48_RS03635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB48_RS03635	COG0072	phenylalanine-tRNA ligase activity
FOB48_RS03640	COG1438	arginine binding
FOB48_RS03645	COG0137	argininosuccinate synthase activity
FOB48_RS03650	COG0165	Argininosuccinate lyase
FOB48_RS03655	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOB48_RS03680	COG0142	geranyltranstransferase activity
FOB48_RS03690	COG1674	ftsk spoiiie
FOB48_RS03730	COG2030	dehydratase
FOB48_RS03740	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOB48_RS03745	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FOB48_RS03750	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FOB48_RS03755	COG0708	Exodeoxyribonuclease III
FOB48_RS03765	COG2837	iron assimilation
FOB48_RS03775	COG1744	ABC transporter substrate-binding protein PnrA-like
FOB48_RS03780	COG3845	ABC transporter
FOB48_RS03785	COG4603	Belongs to the binding-protein-dependent transport system permease family
FOB48_RS03790	COG1079	Belongs to the binding-protein-dependent transport system permease family
FOB48_RS03805	COG1051	belongs to the nudix hydrolase family
FOB48_RS03810	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FOB48_RS03815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOB48_RS03825	COG4770	biotin carboxylase activity
FOB48_RS03830	COG0424	maF-like protein
FOB48_RS03845	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOB48_RS03860	COG0745	RESPONSE REGULATOR receiver
FOB48_RS03910	COG1316	TRANSCRIPTIONal
FOB48_RS03915	COG1216	Glycosyl transferase, family 2
FOB48_RS03930	COG1216	Glycosyl transferase, family 2
FOB48_RS03990	COG5002	protein histidine kinase activity
FOB48_RS03995	COG5401	PFAM Sporulation and spore germination
FOB48_RS04005	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOB48_RS04010	COG0653	protein targeting
FOB48_RS04115	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FOB48_RS04120	COG2884	Cell division ATP-binding protein ftsE
FOB48_RS04125	COG2177	Part of the ABC transporter FtsEX involved in
FOB48_RS04130	COG1196	nuclear chromosome segregation
FOB48_RS04130	COG0741	lytic transglycosylase activity
FOB48_RS04130	COG0739	heme binding
FOB48_RS04135	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FOB48_RS04170	COG0156	8-amino-7-oxononanoate synthase activity
FOB48_RS04175	COG1063	alcohol dehydrogenase
FOB48_RS04180	COG1643	Atp-dependent helicase
FOB48_RS04215	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOB48_RS04225	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FOB48_RS04230	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FOB48_RS04240	COG0406	alpha-ribazole phosphatase activity
FOB48_RS04255	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FOB48_RS04270	COG2197	response regulator
FOB48_RS04275	COG4585	Histidine kinase
FOB48_RS04285	COG1131	(ABC) transporter
FOB48_RS04325	COG3655	Transcriptional regulator
FOB48_RS04345	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOB48_RS04345	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOB48_RS04350	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOB48_RS04350	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOB48_RS04355	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FOB48_RS04375	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FOB48_RS04395	COG0477	Major facilitator Superfamily
FOB48_RS04400	COG0366	Alpha amylase catalytic
FOB48_RS04410	COG4974	Belongs to the 'phage' integrase family
FOB48_RS04565	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FOB48_RS04720	COG1615	UPF0182 protein
FOB48_RS04730	COG3415	Transposase
FOB48_RS04730	COG2801	Transposase and inactivated derivatives
FOB48_RS04750	COG0205	6-phosphofructokinase activity
FOB48_RS04755	COG0483	inositol monophosphate 1-phosphatase activity
FOB48_RS04760	COG1162	GTPase activity
FOB48_RS04765	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FOB48_RS04775	COG1595	DNA-templated transcription, initiation
FOB48_RS04790	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOB48_RS04790	COG0567	Dehydrogenase, E1 component
FOB48_RS04795	COG2205	protein histidine kinase activity
FOB48_RS04800	COG0745	RESPONSE REGULATOR receiver
FOB48_RS04805	COG1253	flavin adenine dinucleotide binding
FOB48_RS04815	COG0739	heme binding
FOB48_RS04815	COG0741	lytic transglycosylase activity
FOB48_RS04815	COG1196	nuclear chromosome segregation
FOB48_RS04820	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FOB48_RS04880	COG2801	Transposase and inactivated derivatives
FOB48_RS04880	COG3415	Transposase
FOB48_RS04895	COG1122	ATPase activity
FOB48_RS04900	COG1132	(ABC) transporter
FOB48_RS04900	COG2375	cellular response to nickel ion
FOB48_RS04905	COG1132	(ABC) transporter
FOB48_RS04910	COG3328	transposase activity
FOB48_RS04925	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FOB48_RS04930	COG0019	diaminopimelate decarboxylase activity
FOB48_RS04935	COG0083	homoserine kinase activity
FOB48_RS04945	COG0254	rRNA binding
FOB48_RS04950	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOB48_RS04960	COG0009	L-threonylcarbamoyladenylate synthase
FOB48_RS04965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOB48_RS04975	COG0356	it plays a direct role in the translocation of protons across the membrane
FOB48_RS04980	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOB48_RS04985	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FOB48_RS04990	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOB48_RS04995	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FOB48_RS05000	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FOB48_RS05005	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FOB48_RS05010	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FOB48_RS05020	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOB48_RS05025	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
FOB48_RS05045	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FOB48_RS05050	COG0366	Alpha amylase catalytic
FOB48_RS05060	COG0714	Associated with various cellular activities
FOB48_RS05095	COG0482	sulfurtransferase activity
FOB48_RS05115	COG0714	Associated with various cellular activities
FOB48_RS05135	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOB48_RS05140	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOB48_RS05145	COG0154	amidase activity
FOB48_RS05150	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOB48_RS05155	COG1115	amino acid carrier protein
FOB48_RS05160	COG1115	amino acid carrier protein
FOB48_RS05165	COG0129	dihydroxy-acid dehydratase activity
FOB48_RS05175	COG0440	acetolactate synthase activity
FOB48_RS05180	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOB48_RS05185	COG0473	3-isopropylmalate dehydrogenase activity
FOB48_RS05190	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOB48_RS05195	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOB48_RS05280	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOB48_RS05285	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOB48_RS05315	COG3425	synthase
FOB48_RS05335	COG1414	Transcriptional regulator
FOB48_RS05340	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FOB48_RS05345	COG0066	3-isopropylmalate dehydratase activity
FOB48_RS05350	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOB48_RS05360	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FOB48_RS05365	COG1181	Belongs to the D-alanine--D-alanine ligase family
FOB48_RS05375	COG0456	acetyltransferase
FOB48_RS05375	COG0454	-acetyltransferase
FOB48_RS05390	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FOB48_RS05400	COG0742	ribosomal rna small subunit methyltransferase
FOB48_RS05405	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FOB48_RS05415	COG0571	ribonuclease III activity
FOB48_RS05420	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOB48_RS05430	COG4585	Histidine kinase
FOB48_RS05435	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOB48_RS05440	COG4988	ABC transporter
FOB48_RS05445	COG1294	oxidase, subunit
FOB48_RS05450	COG1271	oxidase subunit
FOB48_RS05455	COG1530	ribonuclease E activity
FOB48_RS05460	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FOB48_RS05465	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FOB48_RS05470	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOB48_RS05480	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FOB48_RS05490	COG0799	negative regulation of ribosome biogenesis
FOB48_RS05505	COG0823	Involved in the tonB-independent uptake of proteins
FOB48_RS05505	COG1506	peptidase
FOB48_RS05515	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOB48_RS05540	COG0300	oxidoreductase activity
FOB48_RS05555	COG3104	oligopeptide transport
FOB48_RS05565	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FOB48_RS05585	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOB48_RS05590	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOB48_RS05605	COG0640	Transcriptional regulator
FOB48_RS05610	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOB48_RS05615	COG0723	plastoquinol--plastocyanin reductase activity
FOB48_RS05620	COG2010	Cytochrome c
FOB48_RS05625	COG1845	cytochrome c oxidase, subunit III
FOB48_RS05630	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOB48_RS05650	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FOB48_RS05665	COG0142	geranyltranstransferase activity
FOB48_RS05675	COG0589	response to stress
FOB48_RS05680	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOB48_RS05690	COG0187	DNA topoisomerase II activity
FOB48_RS05700	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOB48_RS05735	COG0756	dUTP diphosphatase activity
FOB48_RS05760	COG0569	domain protein
FOB48_RS05765	COG0531	amino acid
FOB48_RS05770	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOB48_RS05775	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOB48_RS05785	COG0024	Methionine aminopeptidase
FOB48_RS05800	COG1131	(ABC) transporter
FOB48_RS05815	COG0719	Fe-S assembly protein
FOB48_RS05825	COG0396	ATPase activity
FOB48_RS05830	COG2151	metal-sulfur cluster biosynthetic enzyme
FOB48_RS05840	COG0686	Belongs to the AlaDH PNT family
FOB48_RS05845	COG0488	(ABC) transporter
FOB48_RS05850	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FOB48_RS05855	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOB48_RS05860	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FOB48_RS05865	COG0194	GDP metabolic process
FOB48_RS05870	COG0194	GDP metabolic process
FOB48_RS05875	COG1758	RNA polymerase activity
FOB48_RS05885	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FOB48_RS05890	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOB48_RS05905	COG0134	indole-3-glycerol-phosphate synthase activity
FOB48_RS05910	COG0133	tryptophan synthase activity
FOB48_RS05915	COG0159	tryptophan synthase activity
FOB48_RS05920	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FOB48_RS05965	COG0539	negative regulation of cytoplasmic translation
FOB48_RS05970	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FOB48_RS05975	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOB48_RS05980	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FOB48_RS05985	COG2860	membrane
FOB48_RS05990	COG0237	dephospho-CoA kinase activity
FOB48_RS05995	COG0556	nucleotide-excision repair
FOB48_RS06000	COG1881	PFAM PEBP family protein
FOB48_RS06005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOB48_RS06015	COG0322	excinuclease ABC activity
FOB48_RS06020	COG1660	Displays ATPase and GTPase activities
FOB48_RS06025	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FOB48_RS06035	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOB48_RS06040	COG0126	phosphoglycerate kinase activity
FOB48_RS06045	COG0149	triose-phosphate isomerase activity
FOB48_RS06050	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOB48_RS06055	COG0710	3-dehydroquinate dehydratase activity
FOB48_RS06060	COG0363	glucosamine-6-phosphate deaminase activity
FOB48_RS06070	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOB48_RS06080	COG0109	protoheme IX farnesyltransferase activity
FOB48_RS06105	COG1160	GTP binding
FOB48_RS06125	COG1716	ATPase activity
FOB48_RS06135	COG1192	Involved in chromosome partitioning
FOB48_RS06145	COG1054	Belongs to the UPF0176 family
FOB48_RS06150	COG2801	Transposase and inactivated derivatives
FOB48_RS06150	COG3415	Transposase
FOB48_RS06165	COG2409	Drug exporters of the RND superfamily
FOB48_RS06175	COG0587	DNA-directed DNA polymerase activity
FOB48_RS06195	COG1119	ATPase activity
FOB48_RS06210	COG0297	glycogen (starch) synthase activity
FOB48_RS06225	COG1028	Short-chain dehydrogenase reductase Sdr
FOB48_RS06240	COG0584	glycerophosphoryl diester phosphodiesterase
FOB48_RS06255	COG0463	Glycosyl transferase, family 2
FOB48_RS06270	COG1597	lipid kinase activity
FOB48_RS06275	COG0805	protein transport
FOB48_RS06280	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOB48_RS06300	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOB48_RS06310	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOB48_RS06325	COG0545	Peptidyl-prolyl cis-trans isomerase
FOB48_RS06330	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FOB48_RS06335	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FOB48_RS06340	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FOB48_RS06355	COG1222	aaa ATPase
FOB48_RS06365	COG0517	IMP dehydrogenase activity
FOB48_RS06365	COG1994	Peptidase M50
FOB48_RS06375	COG1968	undecaprenyl-diphosphatase activity
FOB48_RS06405	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOB48_RS06410	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FOB48_RS06420	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FOB48_RS06425	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOB48_RS06430	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FOB48_RS06450	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FOB48_RS06455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOB48_RS06460	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOB48_RS06470	COG0321	lipoyl(octanoyl) transferase activity
FOB48_RS06475	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FOB48_RS06490	COG0174	glutamine synthetase
FOB48_RS06500	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FOB48_RS06505	COG0174	glutamine synthetase
FOB48_RS06510	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FOB48_RS06525	COG1940	carbohydrate kinase activity
FOB48_RS06535	COG3022	response to hydroperoxide
FOB48_RS06540	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOB48_RS06545	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOB48_RS06550	COG0822	iron-sulfur transferase activity
FOB48_RS06600	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FOB48_RS06615	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOB48_RS06620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOB48_RS06655	COG0358	DNA primase activity
FOB48_RS06660	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FOB48_RS06670	COG0423	glycine-tRNA ligase activity
FOB48_RS06675	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOB48_RS06675	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOB48_RS06680	COG1121	(ABC) transporter
FOB48_RS06685	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOB48_RS06695	COG0586	Pfam SNARE associated Golgi protein
FOB48_RS06700	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOB48_RS06705	COG1381	Involved in DNA repair and RecF pathway recombination
FOB48_RS06710	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOB48_RS06715	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOB48_RS06725	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FOB48_RS06735	COG0537	adenosine 5'-monophosphoramidase activity
FOB48_RS06740	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOB48_RS06745	COG0484	heat shock protein binding
FOB48_RS06750	COG1420	regulation of RNA biosynthetic process
FOB48_RS06765	COG2258	MOSC domain
FOB48_RS06770	COG0481	GTPase activity
FOB48_RS06780	COG0268	Binds directly to 16S ribosomal RNA
FOB48_RS06815	COG1555	photosystem II stabilization
FOB48_RS06815	COG1596	polysaccharide export
FOB48_RS06825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOB48_RS06830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOB48_RS06840	COG1082	Xylose isomerase domain protein TIM barrel
FOB48_RS06845	COG1435	thymidine kinase activity
FOB48_RS06850	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FOB48_RS06860	COG0477	Major facilitator Superfamily
FOB48_RS06865	COG1309	transcriptional regulator
FOB48_RS06880	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB48_RS06885	COG0390	transport system, permease component
FOB48_RS06900	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOB48_RS06900	COG1648	precorrin-2 dehydrogenase activity
FOB48_RS06905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOB48_RS06915	COG2818	Glycosylase
FOB48_RS06920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOB48_RS06925	COG0124	histidyl-tRNA synthetase
FOB48_RS06935	COG1196	nuclear chromosome segregation
FOB48_RS06945	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOB48_RS06950	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOB48_RS06955	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOB48_RS06960	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOB48_RS06965	COG1862	Preprotein translocase
FOB48_RS06970	COG2255	four-way junction helicase activity
FOB48_RS06975	COG0632	four-way junction helicase activity
FOB48_RS06980	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FOB48_RS06985	COG0217	transcriptional regulatory protein
FOB48_RS07000	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOB48_RS07005	COG0039	L-malate dehydrogenase activity
FOB48_RS07060	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOB48_RS07070	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FOB48_RS07075	COG0494	nUDIX hydrolase
FOB48_RS07105	COG0497	DNA recombination
FOB48_RS07110	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOB48_RS07120	COG0647	UMP catabolic process
FOB48_RS07145	COG2226	methyltransferase
FOB48_RS07150	COG2252	PERMEase
FOB48_RS07155	COG0363	glucosamine-6-phosphate deaminase activity
FOB48_RS07160	COG1252	NADH dehydrogenase
FOB48_RS07180	COG0148	phosphopyruvate hydratase activity
FOB48_RS07195	COG0193	aminoacyl-tRNA hydrolase activity
FOB48_RS07200	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FOB48_RS07210	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FOB48_RS07220	COG1309	transcriptional regulator
FOB48_RS07240	COG0488	(ABC) transporter
FOB48_RS07245	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOB48_RS07250	COG0084	hydrolase, TatD family'
FOB48_RS07285	COG0483	inositol monophosphate 1-phosphatase activity
FOB48_RS07300	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOB48_RS07325	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOB48_RS07335	COG1970	mechanosensitive ion channel activity
FOB48_RS07355	COG0579	oxidoreductase
FOB48_RS07360	COG2017	converts alpha-aldose to the beta-anomer
FOB48_RS07375	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FOB48_RS07405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOB48_RS07410	COG0302	gtp cyclohydrolase
FOB48_RS07415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOB48_RS07420	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FOB48_RS07425	COG0037	tRNA processing
FOB48_RS07435	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FOB48_RS07445	COG0242	peptide deformylase activity
FOB48_RS07450	COG3842	ATPase activity
FOB48_RS07465	COG0215	cysteine-tRNA ligase activity
FOB48_RS07475	COG1609	Transcriptional regulator
FOB48_RS07480	COG1760	l-serine dehydratase
FOB48_RS07485	COG0513	Belongs to the DEAD box helicase family
FOB48_RS07490	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FOB48_RS07505	COG0495	leucyl-tRNA aminoacylation
FOB48_RS07515	COG0542	response to heat
FOB48_RS07525	COG0318	PFAM AMP-dependent synthetase and ligase
FOB48_RS07530	COG0009	L-threonylcarbamoyladenylate synthase
FOB48_RS07565	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOB48_RS07565	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOB48_RS07570	COG0509	glycine decarboxylation via glycine cleavage system
FOB48_RS07575	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FOB48_RS07585	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOB48_RS07590	COG0180	Tryptophanyl-tRNA synthetase
FOB48_RS07610	COG3833	ABC-type maltose transport systems, permease component
FOB48_RS07615	COG0366	Alpha amylase catalytic
FOB48_RS07620	COG0366	Alpha amylase catalytic
FOB48_RS07625	COG1414	Transcriptional regulator
FOB48_RS07630	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOB48_RS07655	COG0438	transferase activity, transferring glycosyl groups
FOB48_RS07665	COG0438	transferase activity, transferring glycosyl groups
FOB48_RS07670	COG0789	Transcriptional regulator
FOB48_RS07675	COG0484	heat shock protein binding
FOB48_RS07680	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FOB48_RS07685	COG0443	Heat shock 70 kDa protein
FOB48_RS07690	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOB48_RS07690	COG2169	Transcriptional regulator
FOB48_RS07695	COG1126	abc transporter atp-binding protein
FOB48_RS07700	COG0765	amino acid transport
FOB48_RS07705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB48_RS07710	COG0626	cystathionine gamma-synthase activity
FOB48_RS07715	COG4591	ABC-type transport system involved in lipoprotein release permease component
FOB48_RS07715	COG1136	(ABC) transporter
FOB48_RS07720	COG0577	efflux transmembrane transporter activity
FOB48_RS07720	COG1136	(ABC) transporter
FOB48_RS07735	COG2855	membrane
FOB48_RS07740	COG3590	peptidase
FOB48_RS07755	COG4721	ABC-type cobalt transport system, permease component
FOB48_RS07785	COG0395	ABC-type sugar transport system, permease component
FOB48_RS07795	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FOB48_RS07800	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FOB48_RS07805	COG1737	Transcriptional regulator
FOB48_RS07810	COG1649	PFAM Uncharacterised BCR, COG1649
FOB48_RS07815	COG1446	asparaginase
FOB48_RS07835	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOB48_RS07840	COG1132	(ABC) transporter
FOB48_RS07845	COG1132	(ABC) transporter
FOB48_RS07855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB48_RS07855	COG1263	PTS System
FOB48_RS07855	COG2190	(PTS) system
FOB48_RS07865	COG1921	L-seryl-tRNASec selenium transferase activity
FOB48_RS07875	COG0709	Synthesizes selenophosphate from selenide and ATP
FOB48_RS07890	COG0437	4 iron, 4 sulfur cluster binding
FOB48_RS07895	COG3383	formate dehydrogenase (NAD+) activity
FOB48_RS07895	COG0243	molybdopterin cofactor binding
FOB48_RS07900	COG0243	molybdopterin cofactor binding
FOB48_RS07900	COG3383	formate dehydrogenase (NAD+) activity
FOB48_RS07910	COG0668	transmembrane transport
FOB48_RS07930	COG3265	gluconokinase activity
FOB48_RS07940	COG1946	Acyl-CoA thioesterase
FOB48_RS07950	COG1653	transport
FOB48_RS07975	COG1129	ABC transporter
FOB48_RS07980	COG1725	Transcriptional regulator
FOB48_RS07995	COG3480	Lon protease (S16) C-terminal proteolytic domain
FOB48_RS08010	COG1451	nucleotide metabolic process
FOB48_RS08050	COG0513	Belongs to the DEAD box helicase family
FOB48_RS08060	COG0613	PHP domain protein
FOB48_RS08065	COG0006	proline dipeptidase activity
FOB48_RS08070	COG2239	Acts as a magnesium transporter
FOB48_RS08085	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOB48_RS08100	COG1611	Belongs to the LOG family
FOB48_RS08105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOB48_RS08110	COG2171	N-acyltransferase activity
FOB48_RS08140	COG3842	ATPase activity
FOB48_RS08145	COG3833	ABC-type maltose transport systems, permease component
FOB48_RS08170	COG1217	gtp-binding protein TYPA
FOB48_RS08175	COG0166	Belongs to the GPI family
FOB48_RS08190	COG0428	transporter
FOB48_RS08195	COG2838	Isocitrate dehydrogenase
FOB48_RS08200	COG3158	transport of potassium into the cell
FOB48_RS08210	COG2326	polyphosphate kinase activity
FOB48_RS08220	COG2354	Protein conserved in bacteria
FOB48_RS08230	COG2409	Drug exporters of the RND superfamily
FOB48_RS08290	COG1120	ATPase activity
FOB48_RS08295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB48_RS08300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB48_RS08305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOB48_RS08330	COG3415	Transposase
FOB48_RS08330	COG2801	Transposase and inactivated derivatives
FOB48_RS08335	COG0659	secondary active sulfate transmembrane transporter activity
FOB48_RS08390	COG0012	GTP binding
FOB48_RS08400	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FOB48_RS08405	COG1570	exodeoxyribonuclease VII activity
FOB48_RS08410	COG1722	exodeoxyribonuclease VII activity
FOB48_RS08445	COG0114	fumarate hydratase activity
FOB48_RS08450	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FOB48_RS08455	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOB48_RS08470	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOB48_RS08480	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOB48_RS08495	COG1131	(ABC) transporter
FOB48_RS08520	COG1214	PFAM Peptidase M22, glycoprotease
FOB48_RS08520	COG0456	acetyltransferase
FOB48_RS08525	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOB48_RS08530	COG0736	holo-[acyl-carrier-protein] synthase activity
FOB48_RS08535	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOB48_RS08540	COG1072	(Pantothenic acid kinase))
FOB48_RS08545	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOB48_RS08550	COG2985	domain, Protein
FOB48_RS08550	COG0569	domain protein
FOB48_RS08555	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FOB48_RS08560	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FOB48_RS08565	COG0101	tRNA pseudouridine synthase activity
FOB48_RS08570	COG0151	Belongs to the GarS family
FOB48_RS08575	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FOB48_RS08580	COG1882	Formate acetyltransferase
FOB48_RS08600	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOB48_RS08605	COG0047	phosphoribosylformylglycinamidine synthase activity
FOB48_RS08610	COG2813	Specifically methylates the guanine in position
FOB48_RS08630	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOB48_RS08640	COG0203	ribosomal protein L17
FOB48_RS08645	COG0202	RNA polymerase activity
FOB48_RS08650	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FOB48_RS08655	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOB48_RS08665	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FOB48_RS08670	COG0024	Methionine aminopeptidase
FOB48_RS08675	COG0563	adenylate kinase activity
FOB48_RS08680	COG0201	protein transport
FOB48_RS08685	COG0200	Binds to the 23S rRNA
FOB48_RS08690	COG1841	ribosomal large subunit assembly
FOB48_RS08695	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FOB48_RS08700	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FOB48_RS08705	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOB48_RS08710	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FOB48_RS08720	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FOB48_RS08725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FOB48_RS08730	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FOB48_RS08735	COG2205	protein histidine kinase activity
FOB48_RS08765	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FOB48_RS08770	COG0255	Belongs to the universal ribosomal protein uL29 family
FOB48_RS08775	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FOB48_RS08780	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FOB48_RS08785	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FOB48_RS08790	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FOB48_RS08795	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FOB48_RS08800	COG0089	rRNA binding
FOB48_RS08805	COG0088	Forms part of the polypeptide exit tunnel
FOB48_RS08810	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FOB48_RS08815	COG0051	transcription antitermination factor activity, RNA binding
FOB48_RS08825	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FOB48_RS08830	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FOB48_RS08835	COG0049	tRNA binding
FOB48_RS08840	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FOB48_RS08845	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FOB48_RS08850	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FOB48_RS08855	COG0085	RNA polymerase activity
FOB48_RS08860	COG1136	(ABC) transporter
FOB48_RS08890	COG0222	ribosome binding
FOB48_RS08895	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FOB48_RS08900	COG1454	alcohol dehydrogenase
FOB48_RS08900	COG1012	belongs to the aldehyde dehydrogenase family
FOB48_RS08905	COG0673	inositol 2-dehydrogenase activity
FOB48_RS08910	COG3104	oligopeptide transport
FOB48_RS08915	COG0081	regulation of translation
FOB48_RS08940	COG0436	Aminotransferase
FOB48_RS08945	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FOB48_RS08950	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FOB48_RS08975	COG2326	polyphosphate kinase activity
FOB48_RS08980	COG0138	bifunctional purine biosynthesis protein purh
FOB48_RS09000	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOB48_RS09005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOB48_RS09010	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FOB48_RS09015	COG4948	Mandelate Racemase Muconate Lactonizing
FOB48_RS09020	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FOB48_RS09025	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOB48_RS09050	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FOB48_RS09055	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOB48_RS09065	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOB48_RS09075	COG0785	Cytochrome C biogenesis protein
FOB48_RS09085	COG0406	alpha-ribazole phosphatase activity
FOB48_RS09095	COG2353	YceI-like domain
FOB48_RS09120	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOB48_RS09125	COG0569	domain protein
FOB48_RS09130	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOB48_RS09150	COG0746	molybdenum cofactor guanylyltransferase activity
FOB48_RS09185	COG0395	ABC-type sugar transport system, permease component
FOB48_RS09190	COG1175	transmembrane transport
FOB48_RS09200	COG1846	Transcriptional regulator
FOB48_RS09200	COG1940	carbohydrate kinase activity
FOB48_RS09225	COG3048	D-serine ammonia-lyase activity
FOB48_RS09280	COG3415	Transposase
FOB48_RS09280	COG2801	Transposase and inactivated derivatives
FOB48_RS09290	COG0045	succinate-CoA ligase (ADP-forming) activity
FOB48_RS09315	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FOB48_RS09320	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FOB48_RS09350	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FOB48_RS09370	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FOB48_RS09385	COG1490	D-aminoacyl-tRNA deacylase activity
FOB48_RS09390	COG0588	phosphoglycerate mutase activity
FOB48_RS09400	COG0433	COG0433 Predicted ATPase
FOB48_RS09410	COG0477	Major facilitator Superfamily
FOB48_RS09425	COG0737	Belongs to the 5'-nucleotidase family
FOB48_RS09455	COG1982	Orn Lys Arg decarboxylase major
FOB48_RS09460	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FOB48_RS09470	COG0531	amino acid
FOB48_RS09475	COG1982	Orn Lys Arg decarboxylase major
FOB48_RS09480	COG0477	Major facilitator Superfamily
FOB48_RS09490	COG0519	Catalyzes the synthesis of GMP from XMP
FOB48_RS09490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FOB48_RS09510	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOB48_RS09515	COG0516	GMP reductase activity
FOB48_RS09525	COG1136	(ABC) transporter
FOB48_RS09525	COG0577	efflux transmembrane transporter activity
FOB48_RS09540	COG0564	pseudouridine synthase activity
FOB48_RS09550	COG0459	protein refolding
FOB48_RS09555	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FOB48_RS09570	COG0315	cyclic pyranopterin monophosphate synthase activity
FOB48_RS09615	COG0747	negative chemotaxis
FOB48_RS09635	COG1653	transport
FOB48_RS09655	COG0246	Mannitol dehydrogenase
FOB48_RS09660	COG1904	glucuronate isomerase
FOB48_RS09665	COG1609	Transcriptional regulator
FOB48_RS09675	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FOB48_RS09705	COG1691	(AIR) carboxylase
FOB48_RS09720	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
FOB48_RS09725	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
FOB48_RS09730	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOB48_RS09735	COG2985	domain, Protein
FOB48_RS09735	COG0569	domain protein
FOB48_RS09745	COG0745	RESPONSE REGULATOR receiver
FOB48_RS09750	COG2205	protein histidine kinase activity
FOB48_RS09760	COG2217	Heavy metal translocating P-type atpase
FOB48_RS09775	COG1505	serine-type exopeptidase activity
FOB48_RS09780	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOB48_RS09780	COG0352	thiamine-phosphate diphosphorylase activity
FOB48_RS09780	COG0351	phosphomethylpyrimidine kinase
FOB48_RS09785	COG0351	phosphomethylpyrimidine kinase
FOB48_RS09790	COG0352	thiamine-phosphate diphosphorylase activity
FOB48_RS09790	COG0351	phosphomethylpyrimidine kinase
FOB48_RS09790	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOB48_RS09810	COG2814	Major facilitator Superfamily
FOB48_RS09815	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOB48_RS09830	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOB48_RS09845	COG5416	Lipopolysaccharide assembly protein A domain
FOB48_RS09850	COG0745	RESPONSE REGULATOR receiver
FOB48_RS09855	COG2205	protein histidine kinase activity
FOB48_RS09860	COG0328	RNA-DNA hybrid ribonuclease activity
FOB48_RS09865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOB48_RS09875	COG0456	acetyltransferase
FOB48_RS09880	COG0459	protein refolding
FOB48_RS09895	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FOB48_RS09920	COG0515	serine threonine protein kinase
FOB48_RS09920	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB48_RS09925	COG2608	mercury ion transmembrane transporter activity
FOB48_RS09945	COG0436	Aminotransferase
FOB48_RS10020	COG0765	amino acid transport
FOB48_RS10030	COG0667	Aldo Keto reductase
FOB48_RS10070	COG0419	ATPase involved in DNA repair
FOB48_RS10075	COG0420	3'-5' exonuclease activity
FOB48_RS10085	COG1525	nuclease
FOB48_RS10085	COG4085	toxin activity
FOB48_RS10085	COG0737	Belongs to the 5'-nucleotidase family
FOB48_RS10090	COG1252	NADH dehydrogenase
FOB48_RS10120	COG1309	transcriptional regulator
FOB48_RS10140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FOB48_RS10170	COG0733	neurotransmitter:sodium symporter activity
FOB48_RS10190	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOB48_RS10195	COG1121	(ABC) transporter
FOB48_RS10200	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOB48_RS10205	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOB48_RS10215	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FOB48_RS10220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB48_RS10265	COG0395	ABC-type sugar transport system, permease component
FOB48_RS10275	COG0395	ABC-type sugar transport system, permease component
FOB48_RS10280	COG1175	transmembrane transport
FOB48_RS10285	COG1653	transport
FOB48_RS10300	COG1609	Transcriptional regulator