HRM2_RS05390 dbcd4e9098022fcfc0e496eff6bdcb23 328 SMART SM00899 249 321 5.4E-19 T 22-04-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 HRM2_RS05390 dbcd4e9098022fcfc0e496eff6bdcb23 328 SMART SM00899 152 223 4.1E-12 T 22-04-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 HRM2_RS05390 dbcd4e9098022fcfc0e496eff6bdcb23 328 SUPERFAMILY SSF46785 12 143 5.98E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS05390 dbcd4e9098022fcfc0e496eff6bdcb23 328 SUPERFAMILY SSF50037 154 222 4.35E-11 T 22-04-2016 IPR008988 Transcriptional repressor, C-terminal HRM2_RS05390 dbcd4e9098022fcfc0e496eff6bdcb23 328 Pfam PF04023 FeoA domain 250 320 6.8E-17 T 22-04-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 HRM2_RS05390 dbcd4e9098022fcfc0e496eff6bdcb23 328 Pfam PF04023 FeoA domain 152 223 4.7E-15 T 22-04-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 HRM2_RS05390 dbcd4e9098022fcfc0e496eff6bdcb23 328 SUPERFAMILY SSF50037 253 321 1.72E-16 T 22-04-2016 IPR008988 Transcriptional repressor, C-terminal HRM2_RS05390 dbcd4e9098022fcfc0e496eff6bdcb23 328 Gene3D G3DSA:1.10.10.10 10 88 8.9E-6 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS05390 dbcd4e9098022fcfc0e496eff6bdcb23 328 PANTHER PTHR33202 1 155 1.2E-19 T 22-04-2016 HRM2_RS05390 dbcd4e9098022fcfc0e496eff6bdcb23 328 Pfam PF01475 Ferric uptake regulator family 26 138 3.9E-22 T 22-04-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 HRM2_RS24235 80cd0a4ba0adf1b9bffb9b17c9084795 491 Gene3D G3DSA:1.10.510.10 120 287 1.7E-28 T 22-04-2016 HRM2_RS24235 80cd0a4ba0adf1b9bffb9b17c9084795 491 Gene3D G3DSA:1.25.40.10 314 476 4.5E-10 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS24235 80cd0a4ba0adf1b9bffb9b17c9084795 491 Pfam PF00069 Protein kinase domain 23 269 3.4E-29 T 22-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 HRM2_RS24235 80cd0a4ba0adf1b9bffb9b17c9084795 491 SUPERFAMILY SSF48452 387 475 3.8E-9 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS24235 80cd0a4ba0adf1b9bffb9b17c9084795 491 SUPERFAMILY SSF48452 314 337 3.8E-9 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS24235 80cd0a4ba0adf1b9bffb9b17c9084795 491 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 143 155 - T 22-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 HRM2_RS24235 80cd0a4ba0adf1b9bffb9b17c9084795 491 PANTHER PTHR24362:SF160 9 308 1.5E-44 T 22-04-2016 HRM2_RS24235 80cd0a4ba0adf1b9bffb9b17c9084795 491 PANTHER PTHR24362 9 308 1.5E-44 T 22-04-2016 HRM2_RS24235 80cd0a4ba0adf1b9bffb9b17c9084795 491 SMART SM00220 20 286 3.9E-22 T 22-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 HRM2_RS24235 80cd0a4ba0adf1b9bffb9b17c9084795 491 SUPERFAMILY SSF56112 10 296 1.89E-47 T 22-04-2016 IPR011009 Protein kinase-like domain HRM2_RS24235 80cd0a4ba0adf1b9bffb9b17c9084795 491 Gene3D G3DSA:3.30.200.20 10 119 1.8E-12 T 22-04-2016 HRM2_RS17300 327705d925fa24c2ae5cca0fcbfced4c 347 Gene3D G3DSA:1.10.1670.10 301 346 1.7E-14 T 22-04-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal HRM2_RS17300 327705d925fa24c2ae5cca0fcbfced4c 347 Gene3D G3DSA:1.10.340.30 183 298 4.1E-25 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 HRM2_RS17300 327705d925fa24c2ae5cca0fcbfced4c 347 SUPERFAMILY SSF48150 175 345 2.62E-31 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 HRM2_RS17300 327705d925fa24c2ae5cca0fcbfced4c 347 SMART SM01009 64 181 1.5E-15 T 22-04-2016 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal HRM2_RS17300 327705d925fa24c2ae5cca0fcbfced4c 347 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 187 334 9.2E-5 T 22-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 HRM2_RS17300 327705d925fa24c2ae5cca0fcbfced4c 347 SUPERFAMILY SSF46689 12 54 6.72E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS17300 327705d925fa24c2ae5cca0fcbfced4c 347 Pfam PF12833 Helix-turn-helix domain 11 53 3.5E-8 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HRM2_RS17300 327705d925fa24c2ae5cca0fcbfced4c 347 PANTHER PTHR10242 128 345 1.8E-64 T 22-04-2016 HRM2_RS17300 327705d925fa24c2ae5cca0fcbfced4c 347 PANTHER PTHR10242 42 107 1.8E-64 T 22-04-2016 HRM2_RS17300 327705d925fa24c2ae5cca0fcbfced4c 347 Gene3D G3DSA:1.10.10.60 11 55 4.5E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS17300 327705d925fa24c2ae5cca0fcbfced4c 347 PANTHER PTHR10242:SF3 128 345 1.8E-64 T 22-04-2016 HRM2_RS17300 327705d925fa24c2ae5cca0fcbfced4c 347 PANTHER PTHR10242:SF3 42 107 1.8E-64 T 22-04-2016 HRM2_RS17300 327705d925fa24c2ae5cca0fcbfced4c 347 Pfam PF06029 AlkA N-terminal domain 64 180 4.3E-23 T 22-04-2016 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal HRM2_RS17300 327705d925fa24c2ae5cca0fcbfced4c 347 SUPERFAMILY SSF55945 64 158 3.3E-20 T 22-04-2016 HRM2_RS17300 327705d925fa24c2ae5cca0fcbfced4c 347 Gene3D G3DSA:3.30.310.20 64 177 5.9E-23 T 22-04-2016 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal HRM2_RS17300 327705d925fa24c2ae5cca0fcbfced4c 347 SMART SM00478 191 345 4.9E-6 T 22-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 HRM2_RS13535 3baab9dbfa7206cd02c7b68eed9e79f8 872 SMART SM00863 654 697 6.4E-17 T 22-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 HRM2_RS13535 3baab9dbfa7206cd02c7b68eed9e79f8 872 Pfam PF01411 tRNA synthetases class II (A) 6 556 1.7E-211 T 22-04-2016 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 HRM2_RS13535 3baab9dbfa7206cd02c7b68eed9e79f8 872 SUPERFAMILY SSF55186 553 708 3.4E-49 T 22-04-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 HRM2_RS13535 3baab9dbfa7206cd02c7b68eed9e79f8 872 PRINTS PR00980 Alanyl-tRNA synthetase signature 74 85 6.2E-31 T 22-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 HRM2_RS13535 3baab9dbfa7206cd02c7b68eed9e79f8 872 PRINTS PR00980 Alanyl-tRNA synthetase signature 226 239 6.2E-31 T 22-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 HRM2_RS13535 3baab9dbfa7206cd02c7b68eed9e79f8 872 PRINTS PR00980 Alanyl-tRNA synthetase signature 300 313 6.2E-31 T 22-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 HRM2_RS13535 3baab9dbfa7206cd02c7b68eed9e79f8 872 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 6.2E-31 T 22-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 HRM2_RS13535 3baab9dbfa7206cd02c7b68eed9e79f8 872 PRINTS PR00980 Alanyl-tRNA synthetase signature 276 292 6.2E-31 T 22-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 HRM2_RS13535 3baab9dbfa7206cd02c7b68eed9e79f8 872 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 872 178.145 T 22-04-2016 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 HRM2_RS13535 3baab9dbfa7206cd02c7b68eed9e79f8 872 Pfam PF02272 DHHA1 domain 801 868 2.7E-15 T 22-04-2016 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7 HRM2_RS13535 3baab9dbfa7206cd02c7b68eed9e79f8 872 PANTHER PTHR11777 1 868 0.0 T 22-04-2016 HRM2_RS13535 3baab9dbfa7206cd02c7b68eed9e79f8 872 SUPERFAMILY SSF101353 246 458 3.4E-61 T 22-04-2016 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7|Reactome: REACT_71 HRM2_RS13535 3baab9dbfa7206cd02c7b68eed9e79f8 872 PANTHER PTHR11777:SF9 1 868 0.0 T 22-04-2016 HRM2_RS13535 3baab9dbfa7206cd02c7b68eed9e79f8 872 Gene3D G3DSA:3.30.930.10 1 241 3.1E-113 T 22-04-2016 HRM2_RS13535 3baab9dbfa7206cd02c7b68eed9e79f8 872 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 654 697 8.9E-15 T 22-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 HRM2_RS13535 3baab9dbfa7206cd02c7b68eed9e79f8 872 SUPERFAMILY SSF55681 2 245 7.46E-107 T 22-04-2016 HRM2_RS13535 3baab9dbfa7206cd02c7b68eed9e79f8 872 SUPERFAMILY SSF50447 454 553 1.06E-14 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain HRM2_RS13535 3baab9dbfa7206cd02c7b68eed9e79f8 872 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 6 855 1.9E-297 T 22-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 HRM2_RS21750 7ff37b03d5e6b242483cf18da0fbd043 259 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 3.3E-5 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS21750 7ff37b03d5e6b242483cf18da0fbd043 259 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 3.3E-5 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS21750 7ff37b03d5e6b242483cf18da0fbd043 259 SMART SM00866 103 240 5.5E-23 T 22-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 HRM2_RS21750 7ff37b03d5e6b242483cf18da0fbd043 259 SUPERFAMILY SSF64288 72 246 1.57E-34 T 22-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain HRM2_RS21750 7ff37b03d5e6b242483cf18da0fbd043 259 PANTHER PTHR11751 20 106 3.3E-30 T 22-04-2016 HRM2_RS21750 7ff37b03d5e6b242483cf18da0fbd043 259 TIGRFAM TIGR02018 his_ut_repres: histidine utilization repressor 19 246 1.1E-84 T 22-04-2016 IPR010248 Histidine utilization repressor GO:0003677|GO:0006547|GO:0045892 UniPathway: UPA00379 HRM2_RS21750 7ff37b03d5e6b242483cf18da0fbd043 259 Gene3D G3DSA:1.10.10.10 15 87 6.3E-25 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS21750 7ff37b03d5e6b242483cf18da0fbd043 259 PANTHER PTHR11751:SF364 20 106 3.3E-30 T 22-04-2016 HRM2_RS21750 7ff37b03d5e6b242483cf18da0fbd043 259 SMART SM00345 23 82 4.0E-16 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS21750 7ff37b03d5e6b242483cf18da0fbd043 259 Pfam PF07702 UTRA domain 108 240 1.9E-24 T 22-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 HRM2_RS21750 7ff37b03d5e6b242483cf18da0fbd043 259 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 82 3.8E-19 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS21750 7ff37b03d5e6b242483cf18da0fbd043 259 SUPERFAMILY SSF46785 16 86 1.92E-20 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS21750 7ff37b03d5e6b242483cf18da0fbd043 259 Gene3D G3DSA:3.40.1410.10 100 236 1.1E-38 T 22-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 Gene3D G3DSA:3.30.450.20 142 241 5.6E-12 T 22-04-2016 HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 420 433 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 Gene3D G3DSA:3.30.450.20 259 330 5.1E-9 T 22-04-2016 HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 SUPERFAMILY SSF54631 3 132 1.89E-20 T 22-04-2016 HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 SUPERFAMILY SSF55785 140 226 2.44E-10 T 22-04-2016 IPR000014 PAS domain HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 Gene3D G3DSA:3.40.50.300 393 569 1.0E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 Pfam PF00158 Sigma-54 interaction domain 396 562 2.3E-65 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 PANTHER PTHR32071 353 710 6.7E-150 T 22-04-2016 HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 Pfam PF00571 CBS domain 13 67 3.1E-5 T 22-04-2016 IPR000644 CBS domain HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 Pfam PF00571 CBS domain 82 125 5.7E-4 T 22-04-2016 IPR000644 CBS domain HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 SMART SM00116 85 133 14.0 T 22-04-2016 IPR000644 CBS domain HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 SMART SM00116 20 68 0.013 T 22-04-2016 IPR000644 CBS domain HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 Gene3D G3DSA:3.10.580.10 9 132 2.3E-21 T 22-04-2016 HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 SUPERFAMILY SSF46689 610 710 1.33E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 SUPERFAMILY SSF55785 253 353 2.26E-12 T 22-04-2016 IPR000014 PAS domain HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 SMART SM00091 141 208 0.0016 T 22-04-2016 IPR000014 PAS domain HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 SMART SM00091 258 325 7.1E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 Pfam PF02954 Bacterial regulatory protein, Fis family 672 708 1.0E-10 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 SMART SM00382 416 560 2.4E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 Gene3D G3DSA:1.10.8.60 570 648 1.8E-24 T 22-04-2016 HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 483 498 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 Pfam PF00989 PAS fold 261 320 1.6E-6 T 22-04-2016 IPR013767 PAS fold GO:0006355 HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 Pfam PF00989 PAS fold 143 190 1.7E-6 T 22-04-2016 IPR013767 PAS fold GO:0006355 HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 Gene3D G3DSA:1.10.10.60 658 710 1.3E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 610 619 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 691 710 3.7E-9 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 674 691 3.7E-9 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS22345 7d0daf3f01142b6c82c61049e1b8e2ab 710 SUPERFAMILY SSF52540 396 640 8.36E-72 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04945 4204d31e46378615cbdf1bac8fa8dec7 1091 Gene3D G3DSA:3.40.50.300 200 404 3.5E-34 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04945 4204d31e46378615cbdf1bac8fa8dec7 1091 SUPERFAMILY SSF52540 127 466 8.92E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04945 4204d31e46378615cbdf1bac8fa8dec7 1091 Gene3D G3DSA:3.40.50.280 10 139 8.4E-38 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS04945 4204d31e46378615cbdf1bac8fa8dec7 1091 SUPERFAMILY SSF51703 515 1087 1.73E-143 T 22-04-2016 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 HRM2_RS04945 4204d31e46378615cbdf1bac8fa8dec7 1091 Pfam PF01642 Methylmalonyl-CoA mutase 567 1085 2.3E-133 T 22-04-2016 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 HRM2_RS04945 4204d31e46378615cbdf1bac8fa8dec7 1091 PANTHER PTHR23408 721 1091 2.0E-198 T 22-04-2016 HRM2_RS04945 4204d31e46378615cbdf1bac8fa8dec7 1091 PANTHER PTHR23408 478 698 2.0E-198 T 22-04-2016 HRM2_RS04945 4204d31e46378615cbdf1bac8fa8dec7 1091 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 14 126 1.1E-17 T 22-04-2016 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 HRM2_RS04945 4204d31e46378615cbdf1bac8fa8dec7 1091 Pfam PF03308 ArgK protein 200 466 8.3E-39 T 22-04-2016 HRM2_RS04945 4204d31e46378615cbdf1bac8fa8dec7 1091 Pfam PF02310 B12 binding domain 15 121 9.0E-15 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS04945 4204d31e46378615cbdf1bac8fa8dec7 1091 SUPERFAMILY SSF52242 9 145 7.33E-41 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS04945 4204d31e46378615cbdf1bac8fa8dec7 1091 PANTHER PTHR23408:SF1 721 1091 2.0E-198 T 22-04-2016 HRM2_RS04945 4204d31e46378615cbdf1bac8fa8dec7 1091 PANTHER PTHR23408:SF1 478 698 2.0E-198 T 22-04-2016 HRM2_RS04945 4204d31e46378615cbdf1bac8fa8dec7 1091 Gene3D G3DSA:3.20.20.240 565 1087 2.9E-185 T 22-04-2016 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 HRM2_RS09715 e2309a15b04606b002670511ce66997f 472 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 173 186 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS09715 e2309a15b04606b002670511ce66997f 472 SMART SM00448 3 115 4.2E-25 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS09715 e2309a15b04606b002670511ce66997f 472 Pfam PF00072 Response regulator receiver domain 5 113 4.8E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS09715 e2309a15b04606b002670511ce66997f 472 Gene3D G3DSA:1.10.10.60 433 467 5.1E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS09715 e2309a15b04606b002670511ce66997f 472 Pfam PF00158 Sigma-54 interaction domain 149 314 6.9E-52 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS09715 e2309a15b04606b002670511ce66997f 472 SMART SM00382 169 311 1.2E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS09715 e2309a15b04606b002670511ce66997f 472 SUPERFAMILY SSF52540 149 389 5.33E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09715 e2309a15b04606b002670511ce66997f 472 SUPERFAMILY SSF46689 362 467 1.52E-6 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS09715 e2309a15b04606b002670511ce66997f 472 Gene3D G3DSA:3.40.50.300 145 319 1.1E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09715 e2309a15b04606b002670511ce66997f 472 PANTHER PTHR32071:SF13 5 467 1.2E-180 T 22-04-2016 HRM2_RS09715 e2309a15b04606b002670511ce66997f 472 Pfam PF02954 Bacterial regulatory protein, Fis family 438 467 1.6E-8 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS09715 e2309a15b04606b002670511ce66997f 472 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 361 370 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS09715 e2309a15b04606b002670511ce66997f 472 PANTHER PTHR32071 5 467 1.2E-180 T 22-04-2016 HRM2_RS09715 e2309a15b04606b002670511ce66997f 472 Gene3D G3DSA:1.10.8.60 320 395 4.2E-16 T 22-04-2016 HRM2_RS09715 e2309a15b04606b002670511ce66997f 472 Gene3D G3DSA:3.40.50.2300 5 125 9.9E-31 T 22-04-2016 HRM2_RS09715 e2309a15b04606b002670511ce66997f 472 SUPERFAMILY SSF52172 5 193 1.02E-35 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS09715 e2309a15b04606b002670511ce66997f 472 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 434 451 3.5E-8 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS09715 e2309a15b04606b002670511ce66997f 472 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 451 471 3.5E-8 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS20790 6031de337e26cb520a45481512a851c5 341 SUPERFAMILY SSF46689 229 339 9.41E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS20790 6031de337e26cb520a45481512a851c5 341 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 101 116 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS20790 6031de337e26cb520a45481512a851c5 341 PANTHER PTHR32071:SF38 16 340 2.0E-140 T 22-04-2016 HRM2_RS20790 6031de337e26cb520a45481512a851c5 341 Gene3D G3DSA:1.10.8.60 187 240 3.6E-23 T 22-04-2016 HRM2_RS20790 6031de337e26cb520a45481512a851c5 341 Gene3D G3DSA:1.10.10.60 241 329 2.3E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS20790 6031de337e26cb520a45481512a851c5 341 SUPERFAMILY SSF52540 16 252 2.73E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20790 6031de337e26cb520a45481512a851c5 341 Gene3D G3DSA:3.40.50.300 15 186 2.4E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20790 6031de337e26cb520a45481512a851c5 341 SMART SM00382 35 187 7.4E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS20790 6031de337e26cb520a45481512a851c5 341 PANTHER PTHR32071 16 340 2.0E-140 T 22-04-2016 HRM2_RS20790 6031de337e26cb520a45481512a851c5 341 TIGRFAM TIGR02974 phageshock_pspF: psp operon transcriptional activator 16 339 2.5E-135 T 22-04-2016 IPR014317 Transcription activator PspF HRM2_RS20790 6031de337e26cb520a45481512a851c5 341 Pfam PF00158 Sigma-54 interaction domain 17 177 1.5E-58 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS17335 0c5e78f4e0ac7c62279e492e575e2940 428 SUPERFAMILY SSF55174 349 427 1.22E-11 T 22-04-2016 HRM2_RS17335 0c5e78f4e0ac7c62279e492e575e2940 428 PANTHER PTHR11766 1 427 8.6E-176 T 22-04-2016 IPR024088 Tyrosine-tRNA ligase, bacterial-type GO:0004831 KEGG: 00970+6.1.1.1 HRM2_RS17335 0c5e78f4e0ac7c62279e492e575e2940 428 Gene3D G3DSA:1.10.240.10 232 312 5.4E-32 T 22-04-2016 HRM2_RS17335 0c5e78f4e0ac7c62279e492e575e2940 428 Pfam PF00579 tRNA synthetases class I (W and Y) 30 320 8.2E-81 T 22-04-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS17335 0c5e78f4e0ac7c62279e492e575e2940 428 Gene3D G3DSA:3.40.50.620 3 231 5.1E-96 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS17335 0c5e78f4e0ac7c62279e492e575e2940 428 SUPERFAMILY SSF52374 2 319 7.31E-96 T 22-04-2016 HRM2_RS17335 0c5e78f4e0ac7c62279e492e575e2940 428 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 161 176 9.19E-29 T 22-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 HRM2_RS17335 0c5e78f4e0ac7c62279e492e575e2940 428 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 215 227 9.19E-29 T 22-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 HRM2_RS17335 0c5e78f4e0ac7c62279e492e575e2940 428 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 43 65 9.19E-29 T 22-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 HRM2_RS17335 0c5e78f4e0ac7c62279e492e575e2940 428 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 182 204 9.19E-29 T 22-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 HRM2_RS17335 0c5e78f4e0ac7c62279e492e575e2940 428 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 49 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS17335 0c5e78f4e0ac7c62279e492e575e2940 428 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 4 426 2.4E-121 T 22-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 HRM2_RS17335 0c5e78f4e0ac7c62279e492e575e2940 428 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 1 428 42.513 T 22-04-2016 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 HRM2_RS17335 0c5e78f4e0ac7c62279e492e575e2940 428 Gene3D G3DSA:3.10.290.10 313 427 3.3E-25 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HRM2_RS10345 abc0eb6a9ea8067bb67fb9e77248bc83 886 SUPERFAMILY SSF50677 195 344 1.14E-56 T 22-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 HRM2_RS10345 abc0eb6a9ea8067bb67fb9e77248bc83 886 PANTHER PTHR11946 813 875 0.0 T 22-04-2016 HRM2_RS10345 abc0eb6a9ea8067bb67fb9e77248bc83 886 PANTHER PTHR11946 1 793 0.0 T 22-04-2016 HRM2_RS10345 abc0eb6a9ea8067bb67fb9e77248bc83 886 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 817 881 2.0E-15 T 22-04-2016 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 HRM2_RS10345 abc0eb6a9ea8067bb67fb9e77248bc83 886 Hamap MF_02004 Valine--tRNA ligase [valS]. 6 882 15.578 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 HRM2_RS10345 abc0eb6a9ea8067bb67fb9e77248bc83 886 Gene3D G3DSA:1.10.287.380 811 882 2.1E-4 T 22-04-2016 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 HRM2_RS10345 abc0eb6a9ea8067bb67fb9e77248bc83 886 Gene3D G3DSA:3.40.50.620 8 197 1.1E-148 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS10345 abc0eb6a9ea8067bb67fb9e77248bc83 886 Gene3D G3DSA:3.40.50.620 344 564 1.1E-148 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS10345 abc0eb6a9ea8067bb67fb9e77248bc83 886 SUPERFAMILY SSF47323 578 832 1.53E-60 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS10345 abc0eb6a9ea8067bb67fb9e77248bc83 886 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 47 58 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS10345 abc0eb6a9ea8067bb67fb9e77248bc83 886 Pfam PF08264 Anticodon-binding domain of tRNA 608 757 1.2E-39 T 22-04-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 HRM2_RS10345 abc0eb6a9ea8067bb67fb9e77248bc83 886 PANTHER PTHR11946:SF5 813 875 0.0 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 HRM2_RS10345 abc0eb6a9ea8067bb67fb9e77248bc83 886 PANTHER PTHR11946:SF5 1 793 0.0 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 HRM2_RS10345 abc0eb6a9ea8067bb67fb9e77248bc83 886 SUPERFAMILY SSF52374 6 196 4.29E-145 T 22-04-2016 HRM2_RS10345 abc0eb6a9ea8067bb67fb9e77248bc83 886 SUPERFAMILY SSF52374 344 575 4.29E-145 T 22-04-2016 HRM2_RS10345 abc0eb6a9ea8067bb67fb9e77248bc83 886 TIGRFAM TIGR00422 valS: valine--tRNA ligase 7 860 0.0 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 HRM2_RS10345 abc0eb6a9ea8067bb67fb9e77248bc83 886 Gene3D G3DSA:3.90.740.10 198 339 1.2E-47 T 22-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 HRM2_RS10345 abc0eb6a9ea8067bb67fb9e77248bc83 886 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 18 566 5.3E-201 T 22-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS10345 abc0eb6a9ea8067bb67fb9e77248bc83 886 SUPERFAMILY SSF46589 817 881 8.37E-14 T 22-04-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 HRM2_RS10345 abc0eb6a9ea8067bb67fb9e77248bc83 886 Gene3D G3DSA:1.10.730.10 566 749 5.4E-60 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS10345 abc0eb6a9ea8067bb67fb9e77248bc83 886 PRINTS PR00986 Valyl-tRNA synthetase signature 349 362 4.7E-34 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 HRM2_RS10345 abc0eb6a9ea8067bb67fb9e77248bc83 886 PRINTS PR00986 Valyl-tRNA synthetase signature 478 496 4.7E-34 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 HRM2_RS10345 abc0eb6a9ea8067bb67fb9e77248bc83 886 PRINTS PR00986 Valyl-tRNA synthetase signature 447 468 4.7E-34 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 HRM2_RS10345 abc0eb6a9ea8067bb67fb9e77248bc83 886 PRINTS PR00986 Valyl-tRNA synthetase signature 40 51 4.7E-34 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 HRM2_RS10345 abc0eb6a9ea8067bb67fb9e77248bc83 886 PRINTS PR00986 Valyl-tRNA synthetase signature 234 251 4.7E-34 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 HRM2_RS19655 a41e2df03a3fecf21110cf169bcae5db 242 Pfam PF03167 Uracil DNA glycosylase superfamily 54 219 3.5E-5 T 22-04-2016 IPR005122 Uracil-DNA glycosylase-like HRM2_RS19655 a41e2df03a3fecf21110cf169bcae5db 242 SUPERFAMILY SSF52141 6 240 6.87E-57 T 22-04-2016 IPR005122 Uracil-DNA glycosylase-like HRM2_RS19655 a41e2df03a3fecf21110cf169bcae5db 242 Gene3D G3DSA:3.40.470.10 3 241 2.5E-97 T 22-04-2016 IPR005122 Uracil-DNA glycosylase-like HRM2_RS19655 a41e2df03a3fecf21110cf169bcae5db 242 PANTHER PTHR13235 6 240 8.3E-95 T 22-04-2016 HRM2_RS13095 418d07b12a69570f2ff20d0102b51510 110 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 23 102 2.0E-6 T 22-04-2016 IPR009241 Toxin HigB-like HRM2_RS13095 418d07b12a69570f2ff20d0102b51510 110 PANTHER PTHR41791 11 109 3.7E-28 T 22-04-2016 HRM2_RS13095 418d07b12a69570f2ff20d0102b51510 110 TIGRFAM TIGR02683 upstrm_HI1419: putative addiction module killer protein 18 105 7.2E-37 T 22-04-2016 IPR014056 Addiction module killer protein, predicted HRM2_RS13095 418d07b12a69570f2ff20d0102b51510 110 PANTHER PTHR41791:SF1 11 109 3.7E-28 T 22-04-2016 HRM2_RS13095 418d07b12a69570f2ff20d0102b51510 110 PIRSF PIRSF028744 5 110 2.0E-40 T 22-04-2016 IPR014056 Addiction module killer protein, predicted HRM2_RS13795 6c41adfd45f712f9e51f83fe6bae0350 479 Pfam PF04552 Sigma-54, DNA binding domain 320 478 1.0E-62 T 22-04-2016 IPR007634 RNA polymerase sigma factor 54, DNA-binding HRM2_RS13795 6c41adfd45f712f9e51f83fe6bae0350 479 PIRSF PIRSF000774 1 479 4.5E-156 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 HRM2_RS13795 6c41adfd45f712f9e51f83fe6bae0350 479 PANTHER PTHR32248 2 479 2.3E-143 T 22-04-2016 HRM2_RS13795 6c41adfd45f712f9e51f83fe6bae0350 479 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 7 51 7.3E-16 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 HRM2_RS13795 6c41adfd45f712f9e51f83fe6bae0350 479 Pfam PF04963 Sigma-54 factor, core binding domain 117 304 2.5E-58 T 22-04-2016 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 HRM2_RS13795 6c41adfd45f712f9e51f83fe6bae0350 479 PRINTS PR00045 Sigma-54 factor signature 395 406 1.1E-27 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 HRM2_RS13795 6c41adfd45f712f9e51f83fe6bae0350 479 PRINTS PR00045 Sigma-54 factor signature 190 207 1.1E-27 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 HRM2_RS13795 6c41adfd45f712f9e51f83fe6bae0350 479 PRINTS PR00045 Sigma-54 factor signature 379 391 1.1E-27 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 HRM2_RS13795 6c41adfd45f712f9e51f83fe6bae0350 479 PRINTS PR00045 Sigma-54 factor signature 453 471 1.1E-27 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 HRM2_RS13795 6c41adfd45f712f9e51f83fe6bae0350 479 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 367 386 - T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 HRM2_RS13795 6c41adfd45f712f9e51f83fe6bae0350 479 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 11 477 5.2E-136 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 HRM2_RS13795 6c41adfd45f712f9e51f83fe6bae0350 479 PANTHER PTHR32248:SF4 2 479 2.3E-143 T 22-04-2016 HRM2_RS13795 6c41adfd45f712f9e51f83fe6bae0350 479 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 458 465 - T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 HRM2_RS17775 9bcd03cf18220b8e6eb983e68341aac2 120 Pfam PF01196 Ribosomal protein L17 20 116 6.4E-36 T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17775 9bcd03cf18220b8e6eb983e68341aac2 120 PANTHER PTHR14413:SF5 1 116 1.3E-65 T 22-04-2016 HRM2_RS17775 9bcd03cf18220b8e6eb983e68341aac2 120 TIGRFAM TIGR00059 L17: ribosomal protein bL17 8 116 9.0E-46 T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17775 9bcd03cf18220b8e6eb983e68341aac2 120 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17775 9bcd03cf18220b8e6eb983e68341aac2 120 SUPERFAMILY SSF64263 1 116 1.07E-48 T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17775 9bcd03cf18220b8e6eb983e68341aac2 120 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 26.478 T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17775 9bcd03cf18220b8e6eb983e68341aac2 120 PANTHER PTHR14413 1 116 1.3E-65 T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17775 9bcd03cf18220b8e6eb983e68341aac2 120 Gene3D G3DSA:3.90.1030.10 1 116 2.6E-51 T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS06235 a3c62309171d7d08b3242e07fde64d72 233 Pfam PF03591 AzlC protein 11 151 1.4E-40 T 22-04-2016 IPR011606 Branched-chain amino acid transport, permease HRM2_RS06235 a3c62309171d7d08b3242e07fde64d72 233 PANTHER PTHR34979 1 231 1.2E-48 T 22-04-2016 HRM2_RS00755 853e995cadaebd1931a1ae1679b121bb 464 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 107 389 2.9E-91 T 22-04-2016 IPR004108 Iron hydrogenase, large subunit, C-terminal HRM2_RS00755 853e995cadaebd1931a1ae1679b121bb 464 SMART SM00902 398 457 5.1E-21 T 22-04-2016 IPR003149 Iron hydrogenase, small subunit HRM2_RS00755 853e995cadaebd1931a1ae1679b121bb 464 TIGRFAM TIGR02512 FeFe_hydrog_A: [FeFe] hydrogenase, group A 38 393 5.2E-128 T 22-04-2016 IPR013352 Iron hydrogenase, subset GO:0005506|GO:0008901|GO:0051536|GO:0055114 HRM2_RS00755 853e995cadaebd1931a1ae1679b121bb 464 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 13 24 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS00755 853e995cadaebd1931a1ae1679b121bb 464 Pfam PF02256 Iron hydrogenase small subunit 405 455 4.6E-22 T 22-04-2016 IPR003149 Iron hydrogenase, small subunit HRM2_RS00755 853e995cadaebd1931a1ae1679b121bb 464 Gene3D G3DSA:3.30.70.20 3 44 8.7E-14 T 22-04-2016 HRM2_RS00755 853e995cadaebd1931a1ae1679b121bb 464 SUPERFAMILY SSF53920 42 54 1.16E-126 T 22-04-2016 IPR009016 Iron hydrogenase HRM2_RS00755 853e995cadaebd1931a1ae1679b121bb 464 SUPERFAMILY SSF53920 105 454 1.16E-126 T 22-04-2016 IPR009016 Iron hydrogenase HRM2_RS00755 853e995cadaebd1931a1ae1679b121bb 464 SUPERFAMILY SSF54862 3 54 5.79E-15 T 22-04-2016 HRM2_RS00755 853e995cadaebd1931a1ae1679b121bb 464 Gene3D G3DSA:3.40.50.1780 182 311 1.1E-71 T 22-04-2016 HRM2_RS00755 853e995cadaebd1931a1ae1679b121bb 464 Gene3D G3DSA:3.40.50.1780 45 130 1.1E-71 T 22-04-2016 HRM2_RS00755 853e995cadaebd1931a1ae1679b121bb 464 PANTHER PTHR11615 38 450 6.2E-69 T 22-04-2016 HRM2_RS00755 853e995cadaebd1931a1ae1679b121bb 464 Pfam PF13237 4Fe-4S dicluster domain 6 53 1.2E-7 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS00755 853e995cadaebd1931a1ae1679b121bb 464 Gene3D G3DSA:4.10.260.20 402 457 3.9E-23 T 22-04-2016 IPR003149 Iron hydrogenase, small subunit HRM2_RS00755 853e995cadaebd1931a1ae1679b121bb 464 PANTHER PTHR11615:SF102 38 450 6.2E-69 T 22-04-2016 HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 Pfam PF00575 S1 RNA binding domain 201 266 5.3E-18 T 22-04-2016 IPR003029 S1 domain GO:0003676 HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 Pfam PF00575 S1 RNA binding domain 293 365 2.9E-19 T 22-04-2016 IPR003029 S1 domain GO:0003676 HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 Pfam PF00575 S1 RNA binding domain 380 448 2.0E-8 T 22-04-2016 IPR003029 S1 domain GO:0003676 HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 Pfam PF00575 S1 RNA binding domain 115 183 6.9E-7 T 22-04-2016 IPR003029 S1 domain GO:0003676 HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 PRINTS PR00681 Ribosomal protein S1 signature 120 136 4.5E-44 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 PRINTS PR00681 Ribosomal protein S1 signature 138 155 4.5E-44 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 PRINTS PR00681 Ribosomal protein S1 signature 225 246 4.5E-44 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 PRINTS PR00681 Ribosomal protein S1 signature 36 54 4.5E-44 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 PRINTS PR00681 Ribosomal protein S1 signature 167 187 4.5E-44 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 PRINTS PR00681 Ribosomal protein S1 signature 348 366 4.5E-44 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 PRINTS PR00681 Ribosomal protein S1 signature 54 68 4.5E-44 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 PRINTS PR00681 Ribosomal protein S1 signature 308 327 4.5E-44 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 Gene3D G3DSA:2.40.50.140 378 448 8.3E-14 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 Gene3D G3DSA:2.40.50.140 27 98 1.7E-6 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 SMART SM00316 115 183 2.9E-4 T 22-04-2016 IPR022967 RNA-binding domain, S1 HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 SMART SM00316 293 365 4.9E-23 T 22-04-2016 IPR022967 RNA-binding domain, S1 HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 SMART SM00316 202 277 3.9E-23 T 22-04-2016 IPR022967 RNA-binding domain, S1 HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 SMART SM00316 380 451 1.3E-9 T 22-04-2016 IPR022967 RNA-binding domain, S1 HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 SMART SM00316 34 100 1.7E-4 T 22-04-2016 IPR022967 RNA-binding domain, S1 HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 Gene3D G3DSA:2.40.50.140 196 278 1.2E-23 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 Gene3D G3DSA:2.40.50.140 116 184 2.9E-10 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 SUPERFAMILY SSF50249 202 286 1.51E-20 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 SUPERFAMILY SSF50249 272 386 6.72E-24 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 Gene3D G3DSA:2.40.50.140 295 377 1.6E-23 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 SUPERFAMILY SSF50249 117 193 9.29E-12 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 SUPERFAMILY SSF50249 17 100 1.12E-8 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 PANTHER PTHR10724:SF6 15 473 9.0E-102 T 22-04-2016 HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 SUPERFAMILY SSF50249 360 466 1.42E-14 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS06150 89346a7d540ca95c8ccb3056448f744b 485 PANTHER PTHR10724 15 473 9.0E-102 T 22-04-2016 HRM2_RS06610 e8383c5a2f8847086fe3837705635002 797 PANTHER PTHR33303 13 138 7.3E-83 T 22-04-2016 HRM2_RS06610 e8383c5a2f8847086fe3837705635002 797 Gene3D G3DSA:3.40.50.720 301 441 4.9E-26 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS06610 e8383c5a2f8847086fe3837705635002 797 SUPERFAMILY SSF52210 443 605 1.96E-22 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS06610 e8383c5a2f8847086fe3837705635002 797 PANTHER PTHR33303:SF3 295 707 7.3E-83 T 22-04-2016 HRM2_RS06610 e8383c5a2f8847086fe3837705635002 797 Pfam PF13549 ATP-grasp domain 20 287 1.2E-23 T 22-04-2016 HRM2_RS06610 e8383c5a2f8847086fe3837705635002 797 SUPERFAMILY SSF51735 302 446 2.49E-24 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS06610 e8383c5a2f8847086fe3837705635002 797 SMART SM00881 309 406 9.4E-12 T 22-04-2016 IPR003781 CoA-binding GO:0048037 HRM2_RS06610 e8383c5a2f8847086fe3837705635002 797 Pfam PF13380 CoA binding domain 313 445 3.4E-14 T 22-04-2016 IPR003781 CoA-binding GO:0048037 HRM2_RS06610 e8383c5a2f8847086fe3837705635002 797 Gene3D G3DSA:3.40.50.261 442 603 2.6E-12 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS06610 e8383c5a2f8847086fe3837705635002 797 PANTHER PTHR33303 295 707 7.3E-83 T 22-04-2016 HRM2_RS06610 e8383c5a2f8847086fe3837705635002 797 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 471 604 3.7E-33 T 22-04-2016 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain HRM2_RS06610 e8383c5a2f8847086fe3837705635002 797 SUPERFAMILY SSF52210 617 791 2.35E-19 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS06610 e8383c5a2f8847086fe3837705635002 797 PANTHER PTHR33303:SF3 13 138 7.3E-83 T 22-04-2016 HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 SUPERFAMILY SSF52172 188 305 9.25E-37 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 SUPERFAMILY SSF51971 727 1078 1.29E-27 T 22-04-2016 HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 728 750 3.1E-5 T 22-04-2016 HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 850 859 3.1E-5 T 22-04-2016 HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 Gene3D G3DSA:3.30.70.20 95 121 9.8E-4 T 22-04-2016 HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 Pfam PF00072 Response regulator receiver domain 192 301 4.6E-26 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 Gene3D G3DSA:3.50.50.60 744 882 8.7E-28 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 Gene3D G3DSA:3.50.50.60 1029 1079 8.7E-28 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 PANTHER PTHR26402 190 305 5.6E-40 T 22-04-2016 HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 Pfam PF13450 NAD(P)-binding Rossmann-like domain 10 49 1.7E-6 T 22-04-2016 HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 Pfam PF00037 4Fe-4S binding domain 158 181 3.3E-7 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 Pfam PF00037 4Fe-4S binding domain 111 130 5.8E-6 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 SUPERFAMILY SSF51971 487 555 4.94E-15 T 22-04-2016 HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 SUPERFAMILY SSF51971 309 459 4.94E-15 T 22-04-2016 HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 SUPERFAMILY SSF51971 8 106 4.94E-15 T 22-04-2016 HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 Gene3D G3DSA:3.30.70.20 1094 1155 3.1E-21 T 22-04-2016 HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 Gene3D G3DSA:3.50.50.60 728 743 7.8E-6 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 Gene3D G3DSA:3.50.50.60 912 1006 7.8E-6 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 Pfam PF12838 4Fe-4S dicluster domain 1097 1141 1.8E-6 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 SUPERFAMILY SSF54862 100 186 6.28E-21 T 22-04-2016 HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 Gene3D G3DSA:3.30.70.20 122 203 7.8E-16 T 22-04-2016 HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 Gene3D G3DSA:3.40.50.2300 204 310 9.0E-37 T 22-04-2016 HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 Gene3D G3DSA:3.40.50.720 6 94 9.0E-22 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 Gene3D G3DSA:3.40.50.720 312 402 9.0E-22 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 Pfam PF12831 FAD dependent oxidoreductase 729 766 1.1E-7 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 SMART SM00448 190 301 1.1E-32 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 118 129 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 165 176 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS11285 c796098612d9d541fb79aa5a4ececc90 1161 SUPERFAMILY SSF54862 1062 1147 1.64E-13 T 22-04-2016 HRM2_RS12485 5c4e450e291612ee9271d7f6f91dcc92 310 Pfam PF01699 Sodium/calcium exchanger protein 169 308 5.4E-28 T 22-04-2016 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: REACT_15518 HRM2_RS12485 5c4e450e291612ee9271d7f6f91dcc92 310 Pfam PF01699 Sodium/calcium exchanger protein 5 143 2.1E-24 T 22-04-2016 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: REACT_15518 HRM2_RS12485 5c4e450e291612ee9271d7f6f91dcc92 310 PANTHER PTHR10846 20 307 6.1E-48 T 22-04-2016 IPR004481 Sodium/potassium/calcium exchanger Reactome: REACT_15518 HRM2_RS12485 5c4e450e291612ee9271d7f6f91dcc92 310 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 4 303 2.3E-72 T 22-04-2016 IPR004481 Sodium/potassium/calcium exchanger Reactome: REACT_15518 HRM2_RS11550 146280e5d2baaf6f3ade01d5d300426e 326 SUPERFAMILY SSF53613 7 315 1.31E-67 T 22-04-2016 IPR029056 Ribokinase-like HRM2_RS11550 146280e5d2baaf6f3ade01d5d300426e 326 Pfam PF00294 pfkB family carbohydrate kinase 55 315 8.3E-43 T 22-04-2016 IPR011611 Carbohydrate kinase PfkB HRM2_RS11550 146280e5d2baaf6f3ade01d5d300426e 326 PANTHER PTHR10584 1 326 1.1E-78 T 22-04-2016 HRM2_RS11550 146280e5d2baaf6f3ade01d5d300426e 326 Gene3D G3DSA:3.40.1190.20 4 325 8.7E-64 T 22-04-2016 IPR029056 Ribokinase-like HRM2_RS11550 146280e5d2baaf6f3ade01d5d300426e 326 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 270 283 - T 22-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 HRM2_RS11550 146280e5d2baaf6f3ade01d5d300426e 326 PANTHER PTHR10584:SF153 1 326 1.1E-78 T 22-04-2016 HRM2_RS11875 e14225de4ab98e6c0292649898750945 143 PANTHER PTHR40099 1 143 6.2E-52 T 22-04-2016 HRM2_RS11875 e14225de4ab98e6c0292649898750945 143 Gene3D G3DSA:3.30.70.260 72 128 2.4E-6 T 22-04-2016 HRM2_RS11875 e14225de4ab98e6c0292649898750945 143 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 6 50 8.0E-4 T 22-04-2016 HRM2_RS11875 e14225de4ab98e6c0292649898750945 143 PANTHER PTHR40099:SF1 1 143 6.2E-52 T 22-04-2016 HRM2_RS11875 e14225de4ab98e6c0292649898750945 143 Gene3D G3DSA:3.30.70.260 1 61 1.5E-12 T 22-04-2016 HRM2_RS11875 e14225de4ab98e6c0292649898750945 143 SUPERFAMILY SSF55021 3 66 8.63E-16 T 22-04-2016 HRM2_RS11875 e14225de4ab98e6c0292649898750945 143 SUPERFAMILY SSF55021 71 143 3.93E-15 T 22-04-2016 HRM2_RS11875 e14225de4ab98e6c0292649898750945 143 Pfam PF01842 ACT domain 6 61 1.4E-8 T 22-04-2016 IPR002912 ACT domain GO:0008152|GO:0016597 HRM2_RS11885 caf3d7209800c77ff4cd3e806fff7b98 258 PANTHER PTHR11941 3 257 5.3E-103 T 22-04-2016 HRM2_RS11885 caf3d7209800c77ff4cd3e806fff7b98 258 SUPERFAMILY SSF52096 1 257 4.68E-90 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS11885 caf3d7209800c77ff4cd3e806fff7b98 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 257 1.3E-72 T 22-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 HRM2_RS11885 caf3d7209800c77ff4cd3e806fff7b98 258 Gene3D G3DSA:3.90.226.10 1 257 7.7E-94 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS11885 caf3d7209800c77ff4cd3e806fff7b98 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 22-04-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 HRM2_RS05450 1591556df6b18c33f073e38cc875b5ce 246 Gene3D G3DSA:1.25.40.10 25 107 2.6E-22 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS05450 1591556df6b18c33f073e38cc875b5ce 246 PANTHER PTHR23083 23 232 6.6E-32 T 22-04-2016 HRM2_RS05450 1591556df6b18c33f073e38cc875b5ce 246 Pfam PF13424 Tetratricopeptide repeat 65 121 1.6E-8 T 22-04-2016 HRM2_RS05450 1591556df6b18c33f073e38cc875b5ce 246 Pfam PF13432 Tetratricopeptide repeat 28 62 2.4E-4 T 22-04-2016 HRM2_RS05450 1591556df6b18c33f073e38cc875b5ce 246 Gene3D G3DSA:1.25.40.10 171 232 1.0E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS05450 1591556df6b18c33f073e38cc875b5ce 246 Gene3D G3DSA:1.25.40.10 108 170 1.6E-15 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS05450 1591556df6b18c33f073e38cc875b5ce 246 SMART SM00028 132 165 8.9E-4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS05450 1591556df6b18c33f073e38cc875b5ce 246 SMART SM00028 96 125 0.23 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS05450 1591556df6b18c33f073e38cc875b5ce 246 SMART SM00028 62 95 4.6E-4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS05450 1591556df6b18c33f073e38cc875b5ce 246 SMART SM00028 200 233 12.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS05450 1591556df6b18c33f073e38cc875b5ce 246 SMART SM00028 166 199 230.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS05450 1591556df6b18c33f073e38cc875b5ce 246 SMART SM00028 28 61 12.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS05450 1591556df6b18c33f073e38cc875b5ce 246 SUPERFAMILY SSF48452 28 233 5.69E-26 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS05450 1591556df6b18c33f073e38cc875b5ce 246 Pfam PF13181 Tetratricopeptide repeat 137 164 0.031 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS15460 748e61da494c7ac3c28b5e84ca341330 152 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 11 149 2.2E-50 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 HRM2_RS15460 748e61da494c7ac3c28b5e84ca341330 152 SUPERFAMILY SSF89623 6 149 8.24E-54 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 HRM2_RS15460 748e61da494c7ac3c28b5e84ca341330 152 Pfam PF02502 Ribose/Galactose Isomerase 11 147 1.4E-53 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 HRM2_RS15460 748e61da494c7ac3c28b5e84ca341330 152 PANTHER PTHR30345 1 145 6.6E-70 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 HRM2_RS15460 748e61da494c7ac3c28b5e84ca341330 152 PIRSF PIRSF005384 9 151 2.8E-55 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 HRM2_RS15460 748e61da494c7ac3c28b5e84ca341330 152 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 11 150 6.3E-55 T 22-04-2016 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 HRM2_RS15460 748e61da494c7ac3c28b5e84ca341330 152 Gene3D G3DSA:3.40.1400.10 10 149 2.1E-58 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 HRM2_RS22940 478fd3aef6108a3a9feb6f58052ee436 384 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 176 274 1.3E-16 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HRM2_RS22940 478fd3aef6108a3a9feb6f58052ee436 384 PANTHER PTHR30085 89 381 4.0E-106 T 22-04-2016 HRM2_RS22940 478fd3aef6108a3a9feb6f58052ee436 384 SUPERFAMILY SSF161098 175 369 8.37E-36 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS22940 478fd3aef6108a3a9feb6f58052ee436 384 PANTHER PTHR30085:SF3 89 381 4.0E-106 T 22-04-2016 HRM2_RS22940 478fd3aef6108a3a9feb6f58052ee436 384 Gene3D G3DSA:1.10.3720.10 173 381 1.0E-37 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS22940 478fd3aef6108a3a9feb6f58052ee436 384 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 196 381 1.2E-17 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS20840 1f9be3e16e3314bd1edd233569cac6e6 525 SMART SM00849 13 267 1.1E-7 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS20840 1f9be3e16e3314bd1edd233569cac6e6 525 Gene3D G3DSA:3.60.15.10 181 316 1.0E-44 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS20840 1f9be3e16e3314bd1edd233569cac6e6 525 Gene3D G3DSA:3.60.15.10 2 100 1.0E-44 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS20840 1f9be3e16e3314bd1edd233569cac6e6 525 SUPERFAMILY SSF56281 1 104 1.74E-102 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS20840 1f9be3e16e3314bd1edd233569cac6e6 525 SUPERFAMILY SSF56281 168 524 1.74E-102 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS20840 1f9be3e16e3314bd1edd233569cac6e6 525 PANTHER PTHR11203 1 116 1.7E-108 T 22-04-2016 HRM2_RS20840 1f9be3e16e3314bd1edd233569cac6e6 525 PANTHER PTHR11203 168 525 1.7E-108 T 22-04-2016 HRM2_RS20840 1f9be3e16e3314bd1edd233569cac6e6 525 SMART SM01027 303 429 8.6E-52 T 22-04-2016 IPR022712 Beta-Casp domain HRM2_RS20840 1f9be3e16e3314bd1edd233569cac6e6 525 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 455 517 2.4E-12 T 22-04-2016 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain HRM2_RS20840 1f9be3e16e3314bd1edd233569cac6e6 525 Pfam PF10996 Beta-Casp domain 303 429 6.9E-24 T 22-04-2016 IPR022712 Beta-Casp domain HRM2_RS20840 1f9be3e16e3314bd1edd233569cac6e6 525 Pfam PF00753 Metallo-beta-lactamase superfamily 12 79 4.8E-8 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS20840 1f9be3e16e3314bd1edd233569cac6e6 525 PANTHER PTHR11203:SF11 1 116 1.7E-108 T 22-04-2016 HRM2_RS20840 1f9be3e16e3314bd1edd233569cac6e6 525 PANTHER PTHR11203:SF11 168 525 1.7E-108 T 22-04-2016 HRM2_RS19615 55cc20b8655966e8a89bd9516ec6874b 210 Pfam PF13489 Methyltransferase domain 28 183 5.8E-14 T 22-04-2016 HRM2_RS19615 55cc20b8655966e8a89bd9516ec6874b 210 PANTHER PTHR10108 20 199 2.4E-15 T 22-04-2016 HRM2_RS19615 55cc20b8655966e8a89bd9516ec6874b 210 Gene3D G3DSA:3.40.50.150 8 188 6.1E-29 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS19615 55cc20b8655966e8a89bd9516ec6874b 210 SUPERFAMILY SSF53335 9 192 4.05E-29 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 Pfam PF00391 PEP-utilising enzyme, mobile domain 454 522 1.2E-19 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 748 766 - T 22-04-2016 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 Gene3D G3DSA:3.20.20.60 554 869 1.1E-96 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 Gene3D G3DSA:3.50.30.10 432 551 1.3E-28 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 SUPERFAMILY SSF52009 426 546 4.32E-24 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 PANTHER PTHR22931:SF15 364 851 3.7E-173 T 22-04-2016 HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 SUPERFAMILY SSF51621 555 849 2.22E-93 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 42 179 9.3E-30 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 307 865 1.8E-141 T 22-04-2016 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 552 842 4.3E-94 T 22-04-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 Pfam PF05524 PEP-utilising enzyme, N-terminal 308 426 4.6E-20 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 SUPERFAMILY SSF47831 334 441 4.84E-20 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 Gene3D G3DSA:3.30.1340.10 195 280 7.2E-23 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 SUPERFAMILY SSF55594 196 280 8.5E-20 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 801 813 1.3E-14 T 22-04-2016 HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 593 612 1.3E-14 T 22-04-2016 HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 765 780 1.3E-14 T 22-04-2016 HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 748 763 1.3E-14 T 22-04-2016 HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 Gene3D G3DSA:3.40.930.10 42 179 3.9E-35 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 196 274 2.3E-18 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 PANTHER PTHR22931 364 851 3.7E-173 T 22-04-2016 HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 205 212 - T 22-04-2016 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 SUPERFAMILY SSF55804 41 179 4.19E-34 T 22-04-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 Pfam PF00381 PTS HPr component phosphorylation site 195 275 2.8E-20 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 Gene3D G3DSA:1.10.274.10 332 431 5.3E-21 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 PRINTS PR00107 Phosphocarrier protein signature 246 263 4.5E-12 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 PRINTS PR00107 Phosphocarrier protein signature 231 246 4.5E-12 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like HRM2_RS24965 9e6ea922e775364427aa97712195bdbe 873 PRINTS PR00107 Phosphocarrier protein signature 205 221 4.5E-12 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like HRM2_RS17060 b5808610bfde6f8a53432213551648a1 499 Gene3D G3DSA:1.25.40.10 379 475 4.4E-20 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS17060 b5808610bfde6f8a53432213551648a1 499 SUPERFAMILY SSF48452 186 308 2.07E-30 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS17060 b5808610bfde6f8a53432213551648a1 499 Gene3D G3DSA:1.25.40.10 119 378 1.9E-60 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS17060 b5808610bfde6f8a53432213551648a1 499 SMART SM00028 278 311 3.2E-6 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS17060 b5808610bfde6f8a53432213551648a1 499 SMART SM00028 362 395 0.0011 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS17060 b5808610bfde6f8a53432213551648a1 499 SMART SM00028 160 193 0.42 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS17060 b5808610bfde6f8a53432213551648a1 499 SMART SM00028 320 353 1.0E-4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS17060 b5808610bfde6f8a53432213551648a1 499 SMART SM00028 446 479 1.4E-4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS17060 b5808610bfde6f8a53432213551648a1 499 SMART SM00028 194 227 0.042 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS17060 b5808610bfde6f8a53432213551648a1 499 SMART SM00028 404 437 1.2E-5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS17060 b5808610bfde6f8a53432213551648a1 499 SMART SM00028 236 269 5.8E-4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS17060 b5808610bfde6f8a53432213551648a1 499 SUPERFAMILY SSF48452 272 477 3.58E-39 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS17060 b5808610bfde6f8a53432213551648a1 499 Pfam PF13181 Tetratricopeptide repeat 160 193 0.015 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS17060 b5808610bfde6f8a53432213551648a1 499 Pfam PF13181 Tetratricopeptide repeat 197 224 3.7E-5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS17060 b5808610bfde6f8a53432213551648a1 499 Pfam PF13424 Tetratricopeptide repeat 333 391 6.1E-13 T 22-04-2016 HRM2_RS17060 b5808610bfde6f8a53432213551648a1 499 Pfam PF13424 Tetratricopeptide repeat 402 478 1.1E-16 T 22-04-2016 HRM2_RS17060 b5808610bfde6f8a53432213551648a1 499 Pfam PF13424 Tetratricopeptide repeat 239 307 1.4E-16 T 22-04-2016 HRM2_RS17060 b5808610bfde6f8a53432213551648a1 499 PRINTS PR00381 Kinesin light chain signature 437 458 1.3E-8 T 22-04-2016 IPR002151 Kinesin light chain GO:0003777|GO:0005871 HRM2_RS17060 b5808610bfde6f8a53432213551648a1 499 PRINTS PR00381 Kinesin light chain signature 358 375 1.3E-8 T 22-04-2016 IPR002151 Kinesin light chain GO:0003777|GO:0005871 HRM2_RS17060 b5808610bfde6f8a53432213551648a1 499 PRINTS PR00381 Kinesin light chain signature 402 422 1.3E-8 T 22-04-2016 IPR002151 Kinesin light chain GO:0003777|GO:0005871 HRM2_RS17060 b5808610bfde6f8a53432213551648a1 499 PRINTS PR00381 Kinesin light chain signature 293 311 1.3E-8 T 22-04-2016 IPR002151 Kinesin light chain GO:0003777|GO:0005871 HRM2_RS17060 b5808610bfde6f8a53432213551648a1 499 PANTHER PTHR19959 99 494 3.3E-122 T 22-04-2016 HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 Pfam PF02743 Cache domain 39 332 5.8E-29 T 22-04-2016 IPR033479 Double Cache domain 1 HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 SUPERFAMILY SSF55785 573 699 1.01E-23 T 22-04-2016 IPR000014 PAS domain HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 Gene3D G3DSA:3.40.50.2300 968 1085 8.3E-29 T 22-04-2016 HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 Gene3D G3DSA:3.30.450.20 421 556 2.3E-15 T 22-04-2016 HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 Pfam PF00989 PAS fold 423 529 3.9E-6 T 22-04-2016 IPR013767 PAS fold GO:0006355 HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 Pfam PF00989 PAS fold 586 698 1.0E-11 T 22-04-2016 IPR013767 PAS fold GO:0006355 HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 PRINTS PR00344 Bacterial sensor protein C-terminal signature 880 894 6.4E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 PRINTS PR00344 Bacterial sensor protein C-terminal signature 911 929 6.4E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 PRINTS PR00344 Bacterial sensor protein C-terminal signature 935 948 6.4E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 PRINTS PR00344 Bacterial sensor protein C-terminal signature 898 908 6.4E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 PANTHER PTHR24423 584 1088 2.8E-145 T 22-04-2016 HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 PANTHER PTHR24423 102 550 2.8E-145 T 22-04-2016 HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 Pfam PF00672 HAMP domain 352 419 2.9E-6 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 SMART SM00387 829 951 2.1E-28 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 830 949 1.9E-17 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 SUPERFAMILY SSF55785 413 530 1.61E-13 T 22-04-2016 IPR000014 PAS domain HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 SMART SM00091 586 652 1.7E-9 T 22-04-2016 IPR000014 PAS domain HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 SMART SM00091 423 490 1.3E-4 T 22-04-2016 IPR000014 PAS domain HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 SUPERFAMILY SSF52172 970 1086 3.98E-30 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 Gene3D G3DSA:3.30.450.20 83 127 5.6E-24 T 22-04-2016 HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 Gene3D G3DSA:3.30.450.20 164 218 5.6E-24 T 22-04-2016 HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 PANTHER PTHR24423:SF458 584 1088 2.8E-145 T 22-04-2016 HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 PANTHER PTHR24423:SF458 102 550 2.8E-145 T 22-04-2016 HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 SMART SM00086 659 701 0.0019 T 22-04-2016 IPR001610 PAC motif HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 SMART SM00086 493 535 4.8 T 22-04-2016 IPR001610 PAC motif HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 SUPERFAMILY SSF55874 792 948 3.27E-37 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 SMART SM00448 969 1082 1.1E-25 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 Gene3D G3DSA:3.30.450.20 574 699 5.7E-24 T 22-04-2016 HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 SUPERFAMILY SSF103190 160 227 3.92E-10 T 22-04-2016 IPR029151 Periplasmic sensor domain-like HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 Pfam PF00072 Response regulator receiver domain 971 1082 1.4E-21 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 SUPERFAMILY SSF47384 717 785 1.28E-5 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 Gene3D G3DSA:3.30.565.10 794 948 1.9E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 582 707 2.6E-21 T 22-04-2016 IPR000014 PAS domain HRM2_RS07100 a4a00db78400fdbe9e0d77d60c9fac04 1088 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 420 540 1.0E-9 T 22-04-2016 IPR000014 PAS domain HRM2_RS21435 857184275f8a891dedf0dae880cb637f 782 PANTHER PTHR10283 4 219 3.9E-114 T 22-04-2016 HRM2_RS21435 857184275f8a891dedf0dae880cb637f 782 PANTHER PTHR10283 357 408 3.9E-114 T 22-04-2016 HRM2_RS21435 857184275f8a891dedf0dae880cb637f 782 PANTHER PTHR10283 592 780 3.9E-114 T 22-04-2016 HRM2_RS21435 857184275f8a891dedf0dae880cb637f 782 SUPERFAMILY SSF116726 216 293 1.22E-13 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS21435 857184275f8a891dedf0dae880cb637f 782 Pfam PF02080 TrkA-C domain 501 568 4.5E-9 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS21435 857184275f8a891dedf0dae880cb637f 782 Pfam PF02080 TrkA-C domain 230 292 6.6E-8 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS21435 857184275f8a891dedf0dae880cb637f 782 Pfam PF02080 TrkA-C domain 411 473 8.3E-8 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS21435 857184275f8a891dedf0dae880cb637f 782 SUPERFAMILY SSF116726 495 576 2.09E-15 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS21435 857184275f8a891dedf0dae880cb637f 782 PANTHER PTHR10283:SF100 4 219 3.9E-114 T 22-04-2016 HRM2_RS21435 857184275f8a891dedf0dae880cb637f 782 PANTHER PTHR10283:SF100 357 408 3.9E-114 T 22-04-2016 HRM2_RS21435 857184275f8a891dedf0dae880cb637f 782 PANTHER PTHR10283:SF100 592 780 3.9E-114 T 22-04-2016 HRM2_RS21435 857184275f8a891dedf0dae880cb637f 782 Gene3D G3DSA:3.30.70.1450 409 485 1.2E-15 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS21435 857184275f8a891dedf0dae880cb637f 782 Gene3D G3DSA:3.30.70.1450 314 384 1.1E-10 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS21435 857184275f8a891dedf0dae880cb637f 782 Gene3D G3DSA:3.30.70.1450 223 300 5.9E-15 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS21435 857184275f8a891dedf0dae880cb637f 782 Gene3D G3DSA:3.30.70.1450 498 577 4.1E-18 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS21435 857184275f8a891dedf0dae880cb637f 782 SUPERFAMILY SSF116726 406 480 1.27E-14 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS21435 857184275f8a891dedf0dae880cb637f 782 Pfam PF03600 Citrate transporter 16 726 9.1E-63 T 22-04-2016 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 HRM2_RS21435 857184275f8a891dedf0dae880cb637f 782 SUPERFAMILY SSF116726 311 383 2.22E-10 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS21080 9ad31121f818bd5f181633a0e88535a4 578 Gene3D G3DSA:1.10.1060.10 432 566 1.7E-18 T 22-04-2016 HRM2_RS21080 9ad31121f818bd5f181633a0e88535a4 578 Gene3D G3DSA:1.10.1060.10 18 109 1.1E-23 T 22-04-2016 HRM2_RS21080 9ad31121f818bd5f181633a0e88535a4 578 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 17 93 2.0E-15 T 22-04-2016 IPR028261 Dihydroprymidine dehydrogenase domain II HRM2_RS21080 9ad31121f818bd5f181633a0e88535a4 578 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 548 559 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS21080 9ad31121f818bd5f181633a0e88535a4 578 Gene3D G3DSA:3.50.50.60 203 330 1.0E-29 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS21080 9ad31121f818bd5f181633a0e88535a4 578 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 110 392 1.9E-23 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS21080 9ad31121f818bd5f181633a0e88535a4 578 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 488 499 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS21080 9ad31121f818bd5f181633a0e88535a4 578 PANTHER PTHR11938 17 399 1.1E-135 T 22-04-2016 HRM2_RS21080 9ad31121f818bd5f181633a0e88535a4 578 PRINTS PR00419 Adrenodoxin reductase family signature 110 132 5.0E-13 T 22-04-2016 HRM2_RS21080 9ad31121f818bd5f181633a0e88535a4 578 PRINTS PR00419 Adrenodoxin reductase family signature 241 255 5.0E-13 T 22-04-2016 HRM2_RS21080 9ad31121f818bd5f181633a0e88535a4 578 PRINTS PR00419 Adrenodoxin reductase family signature 133 146 5.0E-13 T 22-04-2016 HRM2_RS21080 9ad31121f818bd5f181633a0e88535a4 578 SUPERFAMILY SSF51971 300 400 7.53E-5 T 22-04-2016 HRM2_RS21080 9ad31121f818bd5f181633a0e88535a4 578 SUPERFAMILY SSF54862 484 568 5.86E-12 T 22-04-2016 HRM2_RS21080 9ad31121f818bd5f181633a0e88535a4 578 Gene3D G3DSA:3.50.50.60 331 400 1.2E-8 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS21080 9ad31121f818bd5f181633a0e88535a4 578 PANTHER PTHR11938:SF100 17 399 1.1E-135 T 22-04-2016 HRM2_RS21080 9ad31121f818bd5f181633a0e88535a4 578 Pfam PF12838 4Fe-4S dicluster domain 488 562 3.4E-10 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS21080 9ad31121f818bd5f181633a0e88535a4 578 Gene3D G3DSA:3.50.50.60 110 202 1.1E-12 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS21080 9ad31121f818bd5f181633a0e88535a4 578 SUPERFAMILY SSF51971 107 337 7.65E-44 T 22-04-2016 HRM2_RS21080 9ad31121f818bd5f181633a0e88535a4 578 SUPERFAMILY SSF46548 17 119 5.75E-16 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS21410 23b88d46f8ac692ae2c67f5967f4fb8a 168 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 95 106 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS21410 23b88d46f8ac692ae2c67f5967f4fb8a 168 Pfam PF13247 4Fe-4S dicluster domain 59 143 1.4E-15 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS21410 23b88d46f8ac692ae2c67f5967f4fb8a 168 PANTHER PTHR11938:SF82 7 149 4.6E-28 T 22-04-2016 HRM2_RS21410 23b88d46f8ac692ae2c67f5967f4fb8a 168 SUPERFAMILY SSF54862 7 160 3.03E-42 T 22-04-2016 HRM2_RS21410 23b88d46f8ac692ae2c67f5967f4fb8a 168 Gene3D G3DSA:3.30.70.20 69 98 1.9E-12 T 22-04-2016 HRM2_RS21410 23b88d46f8ac692ae2c67f5967f4fb8a 168 Pfam PF12800 4Fe-4S binding domain 12 24 0.008 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS21410 23b88d46f8ac692ae2c67f5967f4fb8a 168 Gene3D G3DSA:3.30.70.20 99 132 5.6E-13 T 22-04-2016 HRM2_RS21410 23b88d46f8ac692ae2c67f5967f4fb8a 168 Gene3D G3DSA:3.30.70.20 6 68 4.9E-15 T 22-04-2016 HRM2_RS21410 23b88d46f8ac692ae2c67f5967f4fb8a 168 Gene3D G3DSA:3.30.70.20 133 159 4.9E-15 T 22-04-2016 HRM2_RS21410 23b88d46f8ac692ae2c67f5967f4fb8a 168 PANTHER PTHR11938 7 149 4.6E-28 T 22-04-2016 HRM2_RS14945 9affa485fa547ae178d8e5b4724e3542 544 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 236 518 21.909 T 22-04-2016 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|UniPathway: UPA00248 HRM2_RS14945 9affa485fa547ae178d8e5b4724e3542 544 Gene3D G3DSA:3.40.50.150 290 539 2.3E-62 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS14945 9affa485fa547ae178d8e5b4724e3542 544 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 314 327 - T 22-04-2016 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|UniPathway: UPA00248 HRM2_RS14945 9affa485fa547ae178d8e5b4724e3542 544 SUPERFAMILY SSF53335 242 513 1.15E-62 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS14945 9affa485fa547ae178d8e5b4724e3542 544 Pfam PF01564 Spermine/spermidine synthase 246 476 1.2E-39 T 22-04-2016 HRM2_RS14945 9affa485fa547ae178d8e5b4724e3542 544 PANTHER PTHR11558 258 511 1.4E-69 T 22-04-2016 HRM2_RS14945 9affa485fa547ae178d8e5b4724e3542 544 PANTHER PTHR11558:SF26 258 511 1.4E-69 T 22-04-2016 HRM2_RS24325 4702b01559eca8f705c09b9e8f795981 604 SUPERFAMILY SSF56645 40 270 6.15E-53 T 22-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 HRM2_RS24325 4702b01559eca8f705c09b9e8f795981 604 Gene3D G3DSA:1.10.540.10 41 159 3.5E-15 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS24325 4702b01559eca8f705c09b9e8f795981 604 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 470 597 2.5E-28 T 22-04-2016 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain HRM2_RS24325 4702b01559eca8f705c09b9e8f795981 604 PANTHER PTHR10909 9 479 4.0E-156 T 22-04-2016 HRM2_RS24325 4702b01559eca8f705c09b9e8f795981 604 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 163 270 1.6E-17 T 22-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 HRM2_RS24325 4702b01559eca8f705c09b9e8f795981 604 Gene3D G3DSA:1.20.140.10 276 464 3.9E-50 T 22-04-2016 HRM2_RS24325 4702b01559eca8f705c09b9e8f795981 604 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 285 454 1.2E-23 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS24325 4702b01559eca8f705c09b9e8f795981 604 Gene3D G3DSA:2.40.110.10 162 272 1.7E-24 T 22-04-2016 HRM2_RS24325 4702b01559eca8f705c09b9e8f795981 604 SUPERFAMILY SSF47203 289 476 7.89E-45 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS24325 4702b01559eca8f705c09b9e8f795981 604 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 35 2.8E-9 T 22-04-2016 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria HRM2_RS24325 4702b01559eca8f705c09b9e8f795981 604 PANTHER PTHR10909:SF296 9 479 4.0E-156 T 22-04-2016 HRM2_RS24325 4702b01559eca8f705c09b9e8f795981 604 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 42 158 4.6E-10 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS06635 aba35fe63a60c306c5287bd9204bf445 238 Pfam PF00119 ATP synthase A chain 25 214 2.7E-46 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HRM2_RS06635 aba35fe63a60c306c5287bd9204bf445 238 Hamap MF_01393 ATP synthase subunit a [atpB]. 6 221 13.531 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HRM2_RS06635 aba35fe63a60c306c5287bd9204bf445 238 PANTHER PTHR11410:SF7 12 224 1.9E-50 T 22-04-2016 HRM2_RS06635 aba35fe63a60c306c5287bd9204bf445 238 SUPERFAMILY SSF81336 77 214 1.14E-32 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HRM2_RS06635 aba35fe63a60c306c5287bd9204bf445 238 PRINTS PR00123 ATP synthase A subunit signature 201 216 2.5E-16 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HRM2_RS06635 aba35fe63a60c306c5287bd9204bf445 238 PRINTS PR00123 ATP synthase A subunit signature 141 156 2.5E-16 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HRM2_RS06635 aba35fe63a60c306c5287bd9204bf445 238 PRINTS PR00123 ATP synthase A subunit signature 81 97 2.5E-16 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HRM2_RS06635 aba35fe63a60c306c5287bd9204bf445 238 PRINTS PR00123 ATP synthase A subunit signature 157 179 2.5E-16 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HRM2_RS06635 aba35fe63a60c306c5287bd9204bf445 238 PANTHER PTHR11410 12 224 1.9E-50 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HRM2_RS06635 aba35fe63a60c306c5287bd9204bf445 238 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 20 217 1.4E-33 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HRM2_RS06635 aba35fe63a60c306c5287bd9204bf445 238 Gene3D G3DSA:1.20.120.220 76 219 3.8E-35 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HRM2_RS06635 aba35fe63a60c306c5287bd9204bf445 238 ProSitePatterns PS00449 ATP synthase a subunit signature. 160 169 - T 22-04-2016 IPR023011 ATPase, F0 complex, subunit A, active site HRM2_RS06635 aba35fe63a60c306c5287bd9204bf445 238 TIGRFAM TIGR03306 altF1_A: alternate F1F0 ATPase, F0 subunit A 4 217 1.2E-92 T 22-04-2016 IPR017692 Alternate F1F0 ATPase, F0 subunit A HRM2_RS16075 c6adb342b7a8662f610bafdbba64d6c0 326 Gene3D G3DSA:3.40.190.10 123 252 9.6E-53 T 22-04-2016 HRM2_RS16075 c6adb342b7a8662f610bafdbba64d6c0 326 SUPERFAMILY SSF53850 29 312 1.94E-52 T 22-04-2016 HRM2_RS16075 c6adb342b7a8662f610bafdbba64d6c0 326 PANTHER PTHR30632:SF0 13 231 3.0E-71 T 22-04-2016 HRM2_RS16075 c6adb342b7a8662f610bafdbba64d6c0 326 PANTHER PTHR30632:SF0 257 302 3.0E-71 T 22-04-2016 HRM2_RS16075 c6adb342b7a8662f610bafdbba64d6c0 326 Gene3D G3DSA:3.40.190.10 30 122 5.4E-10 T 22-04-2016 HRM2_RS16075 c6adb342b7a8662f610bafdbba64d6c0 326 Gene3D G3DSA:3.40.190.10 257 298 5.4E-10 T 22-04-2016 HRM2_RS16075 c6adb342b7a8662f610bafdbba64d6c0 326 Pfam PF13531 Bacterial extracellular solute-binding protein 34 287 2.7E-33 T 22-04-2016 HRM2_RS16075 c6adb342b7a8662f610bafdbba64d6c0 326 TIGRFAM TIGR03730 tungstate_WtpA: tungstate ABC transporter binding protein WtpA 31 282 1.7E-108 T 22-04-2016 IPR022498 ABC transporter, tungstate-binding, WtpA GO:1901359 HRM2_RS16075 c6adb342b7a8662f610bafdbba64d6c0 326 PANTHER PTHR30632 13 231 3.0E-71 T 22-04-2016 HRM2_RS16075 c6adb342b7a8662f610bafdbba64d6c0 326 PANTHER PTHR30632 257 302 3.0E-71 T 22-04-2016 HRM2_RS01835 8a05a012e7a91e27f1ee582f5bb8e6ce 105 SMART SM00749 42 105 2.2E-7 T 22-04-2016 IPR014004 Transport-associated and nodulation domain, bacteria HRM2_RS01835 8a05a012e7a91e27f1ee582f5bb8e6ce 105 PANTHER PTHR34606:SF1 3 104 1.2E-29 T 22-04-2016 HRM2_RS01835 8a05a012e7a91e27f1ee582f5bb8e6ce 105 Pfam PF04972 BON domain 37 104 9.3E-20 T 22-04-2016 IPR007055 BON domain HRM2_RS01835 8a05a012e7a91e27f1ee582f5bb8e6ce 105 PANTHER PTHR34606 3 104 1.2E-29 T 22-04-2016 HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 SUPERFAMILY SSF81653 316 414 4.58E-26 T 22-04-2016 HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 222 825 3.8E-178 T 22-04-2016 HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 Pfam PF00122 E1-E2 ATPase 284 507 2.5E-67 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 PRINTS PR00943 Copper-transporting ATPase signature 499 514 6.7E-11 T 22-04-2016 HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 PRINTS PR00943 Copper-transporting ATPase signature 788 802 6.7E-11 T 22-04-2016 HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 PRINTS PR00943 Copper-transporting ATPase signature 225 244 6.7E-11 T 22-04-2016 HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 PRINTS PR00943 Copper-transporting ATPase signature 437 451 6.7E-11 T 22-04-2016 HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 PRINTS PR00943 Copper-transporting ATPase signature 692 709 6.7E-11 T 22-04-2016 HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 PRINTS PR00943 Copper-transporting ATPase signature 303 321 6.7E-11 T 22-04-2016 HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 PRINTS PR00943 Copper-transporting ATPase signature 283 302 6.7E-11 T 22-04-2016 HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 SUPERFAMILY SSF56784 573 822 3.65E-56 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 SUPERFAMILY SSF56784 514 534 3.65E-56 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 640 651 2.9E-27 T 22-04-2016 HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 738 750 2.9E-27 T 22-04-2016 HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 662 672 2.9E-27 T 22-04-2016 HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 715 734 2.9E-27 T 22-04-2016 HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 516 530 2.9E-27 T 22-04-2016 HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 364 378 2.9E-27 T 22-04-2016 HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 PANTHER PTHR24093:SF50 159 828 4.2E-233 T 22-04-2016 HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 Gene3D G3DSA:2.70.150.10 244 415 5.1E-32 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 Gene3D G3DSA:3.40.1110.10 530 642 6.1E-25 T 22-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 Pfam PF04945 YHS domain 26 70 2.2E-11 T 22-04-2016 IPR007029 YHS domain HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 241 824 6.3E-187 T 22-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 SMART SM00746 27 64 3.0E-6 T 22-04-2016 IPR011017 TRASH domain HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 Gene3D G3DSA:3.40.50.1000 487 529 1.8E-53 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 Gene3D G3DSA:3.40.50.1000 643 782 1.8E-53 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 PANTHER PTHR24093 159 828 4.2E-233 T 22-04-2016 HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 Pfam PF00702 haloacid dehalogenase-like hydrolase 512 728 4.0E-38 T 22-04-2016 HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 SUPERFAMILY SSF81665 279 317 3.53E-14 T 22-04-2016 HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 SUPERFAMILY SSF81665 415 510 3.53E-14 T 22-04-2016 HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 SUPERFAMILY SSF81665 764 786 3.53E-14 T 22-04-2016 HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 518 524 - T 22-04-2016 IPR018303 P-type ATPase, phosphorylation site HRM2_RS00195 1035d23fb1d6bc40eefc12446e2268ff 829 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 285 794 2.2E-90 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 HRM2_RS11715 aece224b4d6ba75fd72cd0afb85a62b4 395 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 3 394 9.1E-168 T 22-04-2016 IPR010164 Ornithine aminotransferase GO:0008483|GO:0030170 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|UniPathway: UPA00098 HRM2_RS11715 aece224b4d6ba75fd72cd0afb85a62b4 395 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 8 395 37.311 T 22-04-2016 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 HRM2_RS11715 aece224b4d6ba75fd72cd0afb85a62b4 395 PANTHER PTHR11986:SF18 2 394 9.6E-226 T 22-04-2016 IPR010164 Ornithine aminotransferase GO:0008483|GO:0030170 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|UniPathway: UPA00098 HRM2_RS11715 aece224b4d6ba75fd72cd0afb85a62b4 395 Gene3D G3DSA:3.40.640.10 55 301 1.7E-84 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS11715 aece224b4d6ba75fd72cd0afb85a62b4 395 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 219 256 - T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HRM2_RS11715 aece224b4d6ba75fd72cd0afb85a62b4 395 SUPERFAMILY SSF53383 13 394 1.95E-125 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS11715 aece224b4d6ba75fd72cd0afb85a62b4 395 Pfam PF00202 Aminotransferase class-III 12 394 7.7E-127 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HRM2_RS11715 aece224b4d6ba75fd72cd0afb85a62b4 395 PANTHER PTHR11986 2 394 9.6E-226 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HRM2_RS11715 aece224b4d6ba75fd72cd0afb85a62b4 395 Gene3D G3DSA:3.90.1150.10 7 54 5.1E-42 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS11715 aece224b4d6ba75fd72cd0afb85a62b4 395 Gene3D G3DSA:3.90.1150.10 304 394 5.1E-42 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS08995 9e34a5f35ac4bf6707760fc3d74725e4 174 PANTHER PTHR11670 1 174 4.5E-37 T 22-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS08995 9e34a5f35ac4bf6707760fc3d74725e4 174 Pfam PF00694 Aconitase C-terminal domain 56 111 1.2E-16 T 22-04-2016 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS08995 9e34a5f35ac4bf6707760fc3d74725e4 174 Gene3D G3DSA:3.20.19.10 3 171 2.3E-28 T 22-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel HRM2_RS08995 9e34a5f35ac4bf6707760fc3d74725e4 174 PANTHER PTHR11670:SF6 1 174 4.5E-37 T 22-04-2016 HRM2_RS08995 9e34a5f35ac4bf6707760fc3d74725e4 174 SUPERFAMILY SSF52016 3 172 6.67E-38 T 22-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel HRM2_RS16795 85841f47d056348f632c9c89cc0e801e 413 PANTHER PTHR22893:SF6 1 353 1.5E-141 T 22-04-2016 HRM2_RS16795 85841f47d056348f632c9c89cc0e801e 413 PANTHER PTHR22893 1 353 1.5E-141 T 22-04-2016 HRM2_RS16795 85841f47d056348f632c9c89cc0e801e 413 SUPERFAMILY SSF51395 7 347 8.55E-97 T 22-04-2016 HRM2_RS16795 85841f47d056348f632c9c89cc0e801e 413 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 9 342 2.0E-52 T 22-04-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 HRM2_RS16795 85841f47d056348f632c9c89cc0e801e 413 Gene3D G3DSA:3.20.20.70 3 345 1.2E-110 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS01125 961878f6b173074a03649d630f8c8f39 344 Gene3D G3DSA:3.40.50.1980 65 182 3.6E-17 T 22-04-2016 HRM2_RS01125 961878f6b173074a03649d630f8c8f39 344 PANTHER PTHR30535:SF5 49 332 8.8E-42 T 22-04-2016 HRM2_RS01125 961878f6b173074a03649d630f8c8f39 344 Gene3D G3DSA:3.40.50.1980 185 323 1.7E-19 T 22-04-2016 HRM2_RS01125 961878f6b173074a03649d630f8c8f39 344 PANTHER PTHR30535 49 332 8.8E-42 T 22-04-2016 HRM2_RS01125 961878f6b173074a03649d630f8c8f39 344 SUPERFAMILY SSF53807 51 330 1.06E-49 T 22-04-2016 HRM2_RS01125 961878f6b173074a03649d630f8c8f39 344 Pfam PF01497 Periplasmic binding protein 113 300 5.7E-20 T 22-04-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 HRM2_RS12690 eadfa242e695348fd323336542c23407 143 Pfam PF00717 Peptidase S24-like 1 51 2.0E-5 T 22-04-2016 IPR019759 Peptidase S24/S26A/S26B HRM2_RS12690 eadfa242e695348fd323336542c23407 143 SUPERFAMILY SSF51306 1 75 2.09E-6 T 22-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C HRM2_RS19050 3f250c9935ed03631e59c159a4c252d3 609 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 204 1.1E-80 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS19050 3f250c9935ed03631e59c159a4c252d3 609 PANTHER PTHR30038:SF0 1 608 8.6E-249 T 22-04-2016 HRM2_RS19050 3f250c9935ed03631e59c159a4c252d3 609 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 220 608 2.1E-133 T 22-04-2016 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS19050 3f250c9935ed03631e59c159a4c252d3 609 PANTHER PTHR30038 1 608 8.6E-249 T 22-04-2016 HRM2_RS19050 3f250c9935ed03631e59c159a4c252d3 609 Gene3D G3DSA:1.10.599.10 384 608 1.4E-69 T 22-04-2016 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 HRM2_RS19050 3f250c9935ed03631e59c159a4c252d3 609 SUPERFAMILY SSF56228 1 209 4.19E-77 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS19050 3f250c9935ed03631e59c159a4c252d3 609 Gene3D G3DSA:3.60.9.10 1 209 1.7E-89 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS19050 3f250c9935ed03631e59c159a4c252d3 609 SMART SM00790 4 206 1.5E-121 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS19050 3f250c9935ed03631e59c159a4c252d3 609 SUPERFAMILY SSF48310 211 608 6.41E-122 T 22-04-2016 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 Pfam PF00122 E1-E2 ATPase 276 504 8.1E-63 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 712 731 2.8E-27 T 22-04-2016 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 513 527 2.8E-27 T 22-04-2016 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 355 369 2.8E-27 T 22-04-2016 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 659 669 2.8E-27 T 22-04-2016 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 637 648 2.8E-27 T 22-04-2016 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 735 747 2.8E-27 T 22-04-2016 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 Gene3D G3DSA:3.40.50.1000 484 527 1.2E-53 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 Gene3D G3DSA:3.40.50.1000 640 781 1.2E-53 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 269 814 5.1E-111 T 22-04-2016 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 242 821 5.4E-187 T 22-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 224 822 8.1E-178 T 22-04-2016 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 PANTHER PTHR24093 7 825 4.7E-266 T 22-04-2016 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 PRINTS PR00943 Copper-transporting ATPase signature 207 225 2.7E-14 T 22-04-2016 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 PRINTS PR00943 Copper-transporting ATPase signature 496 511 2.7E-14 T 22-04-2016 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 PRINTS PR00943 Copper-transporting ATPase signature 428 442 2.7E-14 T 22-04-2016 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 PRINTS PR00943 Copper-transporting ATPase signature 227 246 2.7E-14 T 22-04-2016 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 PRINTS PR00943 Copper-transporting ATPase signature 746 760 2.7E-14 T 22-04-2016 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 PRINTS PR00943 Copper-transporting ATPase signature 114 128 2.7E-14 T 22-04-2016 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 PRINTS PR00943 Copper-transporting ATPase signature 689 706 2.7E-14 T 22-04-2016 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 PRINTS PR00943 Copper-transporting ATPase signature 275 294 2.7E-14 T 22-04-2016 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 SUPERFAMILY SSF81653 310 405 5.62E-25 T 22-04-2016 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 Gene3D G3DSA:3.40.1110.10 528 639 5.4E-19 T 22-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 PRINTS PR00942 Copper-transporting ATPase 1 signature 30 53 4.8E-9 T 22-04-2016 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 PRINTS PR00942 Copper-transporting ATPase 1 signature 225 250 4.8E-9 T 22-04-2016 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 PRINTS PR00942 Copper-transporting ATPase 1 signature 4 29 4.8E-9 T 22-04-2016 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 SUPERFAMILY SSF56784 511 531 3.67E-55 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 SUPERFAMILY SSF56784 570 819 3.67E-55 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 SUPERFAMILY SSF55008 96 165 5.24E-19 T 22-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 ProSitePatterns PS01047 Heavy-metal-associated domain. 9 38 - T 22-04-2016 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 ProSitePatterns PS01047 Heavy-metal-associated domain. 104 133 - T 22-04-2016 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 Pfam PF00702 haloacid dehalogenase-like hydrolase 510 726 9.6E-39 T 22-04-2016 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 515 521 - T 22-04-2016 IPR018303 P-type ATPase, phosphorylation site HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 Gene3D G3DSA:3.30.70.100 96 163 3.6E-20 T 22-04-2016 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 SUPERFAMILY SSF81665 761 783 7.06E-13 T 22-04-2016 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 SUPERFAMILY SSF81665 183 241 7.06E-13 T 22-04-2016 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 SUPERFAMILY SSF81665 406 507 7.06E-13 T 22-04-2016 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 Pfam PF00403 Heavy-metal-associated domain 102 161 2.7E-11 T 22-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 Pfam PF00403 Heavy-metal-associated domain 7 66 1.5E-15 T 22-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 Gene3D G3DSA:3.30.70.100 7 70 3.0E-20 T 22-04-2016 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 Gene3D G3DSA:2.70.150.10 241 406 5.3E-31 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 5 66 6.7E-14 T 22-04-2016 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 SUPERFAMILY SSF55008 6 69 6.68E-17 T 22-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 HRM2_RS21305 3d9ba8ac441c891955fa695f2f1b27a5 826 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 278 791 6.1E-82 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 HRM2_RS04385 a03d9b0d266afcd8e8108fb983eeef83 697 Pfam PF07715 TonB-dependent Receptor Plug Domain 60 163 8.0E-24 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 HRM2_RS04385 a03d9b0d266afcd8e8108fb983eeef83 697 Gene3D G3DSA:2.40.170.20 167 690 6.9E-69 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 HRM2_RS04385 a03d9b0d266afcd8e8108fb983eeef83 697 Pfam PF00593 TonB dependent receptor 459 691 1.3E-22 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 HRM2_RS04385 a03d9b0d266afcd8e8108fb983eeef83 697 SUPERFAMILY SSF56935 42 692 2.84E-100 T 22-04-2016 HRM2_RS04385 a03d9b0d266afcd8e8108fb983eeef83 697 PANTHER PTHR32552 13 697 5.9E-56 T 22-04-2016 HRM2_RS04385 a03d9b0d266afcd8e8108fb983eeef83 697 Gene3D G3DSA:2.170.130.10 38 166 2.7E-33 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 HRM2_RS22850 d5fd00fc58bcd6c5813a41304dbe1422 313 PANTHER PTHR32196:SF33 14 311 1.9E-67 T 22-04-2016 HRM2_RS22850 d5fd00fc58bcd6c5813a41304dbe1422 313 PANTHER PTHR32196 14 311 1.9E-67 T 22-04-2016 HRM2_RS22850 d5fd00fc58bcd6c5813a41304dbe1422 313 Pfam PF02653 Branched-chain amino acid transport system / permease component 16 281 1.2E-26 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 HRM2_RS17885 601699e06285aadffebc5c44916fccd4 276 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 5.4E-32 T 22-04-2016 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17885 601699e06285aadffebc5c44916fccd4 276 Gene3D G3DSA:2.40.50.140 1 114 4.2E-49 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS17885 601699e06285aadffebc5c44916fccd4 276 Gene3D G3DSA:4.10.950.10 196 272 1.2E-34 T 22-04-2016 IPR014726 Ribosomal protein L2, domain 3 HRM2_RS17885 601699e06285aadffebc5c44916fccd4 276 SMART SM01383 42 118 4.4E-43 T 22-04-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17885 601699e06285aadffebc5c44916fccd4 276 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 22-04-2016 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 HRM2_RS17885 601699e06285aadffebc5c44916fccd4 276 SUPERFAMILY SSF50104 126 272 5.84E-61 T 22-04-2016 IPR008991 Translation protein SH3-like domain HRM2_RS17885 601699e06285aadffebc5c44916fccd4 276 PANTHER PTHR13691:SF5 1 276 1.8E-137 T 22-04-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 HRM2_RS17885 601699e06285aadffebc5c44916fccd4 276 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 4 273 1.6E-129 T 22-04-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 HRM2_RS17885 601699e06285aadffebc5c44916fccd4 276 Gene3D G3DSA:2.30.30.30 119 194 5.5E-34 T 22-04-2016 IPR014722 Ribosomal protein L2 domain 2 HRM2_RS17885 601699e06285aadffebc5c44916fccd4 276 PANTHER PTHR13691 1 276 1.8E-137 T 22-04-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17885 601699e06285aadffebc5c44916fccd4 276 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 47.255 T 22-04-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 HRM2_RS17885 601699e06285aadffebc5c44916fccd4 276 SUPERFAMILY SSF50249 3 125 2.33E-47 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS17885 601699e06285aadffebc5c44916fccd4 276 PIRSF PIRSF002158 13 275 3.7E-97 T 22-04-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17885 601699e06285aadffebc5c44916fccd4 276 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 250 2.0E-56 T 22-04-2016 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 HRM2_RS17885 601699e06285aadffebc5c44916fccd4 276 SMART SM01382 124 252 3.7E-89 T 22-04-2016 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 HRM2_RS06935 cc5fe9fd858869b4e4f2ea99a03a0857 583 Pfam PF11854 Putative outer membrane beta-barrel porin, MtrB/PioB 164 574 1.4E-21 T 22-04-2016 IPR020016 Decahaem-associated outer membrane protein, MtrB/PioB HRM2_RS06935 cc5fe9fd858869b4e4f2ea99a03a0857 583 SUPERFAMILY SSF56935 295 565 2.66E-10 T 22-04-2016 HRM2_RS06935 cc5fe9fd858869b4e4f2ea99a03a0857 583 SUPERFAMILY SSF56935 157 251 2.66E-10 T 22-04-2016 HRM2_RS05785 fefa5d9f1d6bf198084d2cae2780fb25 163 Pfam PF01750 Hydrogenase maturation protease 28 158 4.5E-23 T 22-04-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 HRM2_RS05785 fefa5d9f1d6bf198084d2cae2780fb25 163 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 11 159 1.0E-33 T 22-04-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 HRM2_RS05785 fefa5d9f1d6bf198084d2cae2780fb25 163 SUPERFAMILY SSF53163 8 162 2.49E-32 T 22-04-2016 IPR023430 Peptidase HybD-like domain HRM2_RS05785 fefa5d9f1d6bf198084d2cae2780fb25 163 Gene3D G3DSA:3.40.50.1450 8 162 6.4E-36 T 22-04-2016 IPR023430 Peptidase HybD-like domain HRM2_RS05785 fefa5d9f1d6bf198084d2cae2780fb25 163 PANTHER PTHR30302 5 162 8.1E-30 T 22-04-2016 HRM2_RS05785 fefa5d9f1d6bf198084d2cae2780fb25 163 PRINTS PR00446 Hydrogen uptake protein signature 22 33 1.4E-12 T 22-04-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 HRM2_RS05785 fefa5d9f1d6bf198084d2cae2780fb25 163 PRINTS PR00446 Hydrogen uptake protein signature 42 59 1.4E-12 T 22-04-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 HRM2_RS05785 fefa5d9f1d6bf198084d2cae2780fb25 163 PRINTS PR00446 Hydrogen uptake protein signature 10 22 1.4E-12 T 22-04-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 HRM2_RS05785 fefa5d9f1d6bf198084d2cae2780fb25 163 PRINTS PR00446 Hydrogen uptake protein signature 67 77 1.4E-12 T 22-04-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 HRM2_RS05785 fefa5d9f1d6bf198084d2cae2780fb25 163 PRINTS PR00446 Hydrogen uptake protein signature 79 95 1.4E-12 T 22-04-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 HRM2_RS11640 f209008d7eaa5fc5e0b7d3356a7b2e44 795 Pfam PF13654 AAA domain 26 541 1.1E-174 T 22-04-2016 HRM2_RS11640 f209008d7eaa5fc5e0b7d3356a7b2e44 795 Gene3D G3DSA:3.30.230.10 563 757 3.0E-28 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HRM2_RS11640 f209008d7eaa5fc5e0b7d3356a7b2e44 795 SUPERFAMILY SSF52540 309 540 2.08E-13 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11640 f209008d7eaa5fc5e0b7d3356a7b2e44 795 SUPERFAMILY SSF52540 31 105 2.08E-13 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11640 f209008d7eaa5fc5e0b7d3356a7b2e44 795 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 650 752 2.2E-9 T 22-04-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 HRM2_RS11640 f209008d7eaa5fc5e0b7d3356a7b2e44 795 SUPERFAMILY SSF52540 51 257 7.27E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11640 f209008d7eaa5fc5e0b7d3356a7b2e44 795 PANTHER PTHR10046:SF46 91 762 2.5E-113 T 22-04-2016 HRM2_RS11640 f209008d7eaa5fc5e0b7d3356a7b2e44 795 Gene3D G3DSA:3.40.50.300 31 95 7.6E-9 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11640 f209008d7eaa5fc5e0b7d3356a7b2e44 795 Gene3D G3DSA:3.40.50.300 295 399 7.6E-9 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11640 f209008d7eaa5fc5e0b7d3356a7b2e44 795 PANTHER PTHR10046 91 762 2.5E-113 T 22-04-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 HRM2_RS11640 f209008d7eaa5fc5e0b7d3356a7b2e44 795 SUPERFAMILY SSF54211 566 759 2.09E-32 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS11640 f209008d7eaa5fc5e0b7d3356a7b2e44 795 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 62 81 2.3E-8 T 22-04-2016 HRM2_RS11640 f209008d7eaa5fc5e0b7d3356a7b2e44 795 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 678 697 2.3E-8 T 22-04-2016 HRM2_RS11640 f209008d7eaa5fc5e0b7d3356a7b2e44 795 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 648 667 2.3E-8 T 22-04-2016 HRM2_RS11640 f209008d7eaa5fc5e0b7d3356a7b2e44 795 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 567 583 2.3E-8 T 22-04-2016 HRM2_RS05005 64cab20ecf2a709309177a36df9ba794 244 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 208 2.4E-23 T 22-04-2016 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type HRM2_RS05005 64cab20ecf2a709309177a36df9ba794 244 PANTHER PTHR11124 97 159 1.2E-47 T 22-04-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 HRM2_RS05005 64cab20ecf2a709309177a36df9ba794 244 PANTHER PTHR11124 181 243 1.2E-47 T 22-04-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 HRM2_RS05005 64cab20ecf2a709309177a36df9ba794 244 PANTHER PTHR11124 1 73 1.2E-47 T 22-04-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 HRM2_RS05005 64cab20ecf2a709309177a36df9ba794 244 SUPERFAMILY SSF56300 1 243 1.21E-49 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS05005 64cab20ecf2a709309177a36df9ba794 244 PANTHER PTHR11124:SF2 97 159 1.2E-47 T 22-04-2016 HRM2_RS05005 64cab20ecf2a709309177a36df9ba794 244 PANTHER PTHR11124:SF2 181 243 1.2E-47 T 22-04-2016 HRM2_RS05005 64cab20ecf2a709309177a36df9ba794 244 PANTHER PTHR11124:SF2 1 73 1.2E-47 T 22-04-2016 HRM2_RS05005 64cab20ecf2a709309177a36df9ba794 244 PIRSF PIRSF000883 1 244 2.7E-57 T 22-04-2016 IPR011152 Phosphoesterase MJ0912 HRM2_RS05005 64cab20ecf2a709309177a36df9ba794 244 Gene3D G3DSA:3.60.21.10 1 243 1.5E-64 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS05865 474974ac01c99970a4ae49b694b80a0e 919 PANTHER PTHR10742:SF263 429 555 4.1E-52 T 22-04-2016 HRM2_RS05865 474974ac01c99970a4ae49b694b80a0e 919 Gene3D G3DSA:3.50.50.60 508 641 4.0E-34 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS05865 474974ac01c99970a4ae49b694b80a0e 919 Gene3D G3DSA:3.50.50.60 785 830 4.0E-34 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS05865 474974ac01c99970a4ae49b694b80a0e 919 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 884 895 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS05865 474974ac01c99970a4ae49b694b80a0e 919 SUPERFAMILY SSF51905 505 831 3.63E-26 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS05865 474974ac01c99970a4ae49b694b80a0e 919 SUPERFAMILY SSF54862 8 153 2.67E-21 T 22-04-2016 HRM2_RS05865 474974ac01c99970a4ae49b694b80a0e 919 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 17 28 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS05865 474974ac01c99970a4ae49b694b80a0e 919 Gene3D G3DSA:3.50.50.60 169 342 1.9E-14 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS05865 474974ac01c99970a4ae49b694b80a0e 919 Gene3D G3DSA:3.30.70.20 831 861 1.4E-6 T 22-04-2016 HRM2_RS05865 474974ac01c99970a4ae49b694b80a0e 919 Gene3D G3DSA:3.30.70.20 670 682 1.4E-6 T 22-04-2016 HRM2_RS05865 474974ac01c99970a4ae49b694b80a0e 919 Gene3D G3DSA:3.30.70.20 862 909 1.1E-14 T 22-04-2016 HRM2_RS05865 474974ac01c99970a4ae49b694b80a0e 919 Gene3D G3DSA:3.30.70.20 11 86 4.7E-13 T 22-04-2016 HRM2_RS05865 474974ac01c99970a4ae49b694b80a0e 919 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 509 809 7.6E-13 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS05865 474974ac01c99970a4ae49b694b80a0e 919 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 56 335 2.0E-18 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS05865 474974ac01c99970a4ae49b694b80a0e 919 Gene3D G3DSA:3.40.50.720 87 168 6.5E-5 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS05865 474974ac01c99970a4ae49b694b80a0e 919 SUPERFAMILY SSF54862 844 901 1.17E-18 T 22-04-2016 HRM2_RS05865 474974ac01c99970a4ae49b694b80a0e 919 SUPERFAMILY SSF51905 6 339 7.12E-19 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS05865 474974ac01c99970a4ae49b694b80a0e 919 PANTHER PTHR10742 429 555 4.1E-52 T 22-04-2016 HRM2_RS05865 474974ac01c99970a4ae49b694b80a0e 919 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 853 864 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS05865 474974ac01c99970a4ae49b694b80a0e 919 Pfam PF12838 4Fe-4S dicluster domain 16 83 1.4E-6 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS05865 474974ac01c99970a4ae49b694b80a0e 919 Pfam PF12838 4Fe-4S dicluster domain 852 898 1.8E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS09190 d6953e2b724a5df848e74f8510471251 293 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 293 5.3E-68 T 22-04-2016 IPR005229 Conserved hypothetical protein CHP00255 HRM2_RS09190 d6953e2b724a5df848e74f8510471251 293 Pfam PF08340 Domain of unknown function (DUF1732) 209 293 1.8E-35 T 22-04-2016 IPR013551 Domain of unknown function DUF1732 HRM2_RS09190 d6953e2b724a5df848e74f8510471251 293 Pfam PF03755 YicC-like family, N-terminal region 2 155 1.3E-34 T 22-04-2016 IPR013527 YicC-like, N-terminal HRM2_RS09190 d6953e2b724a5df848e74f8510471251 293 PANTHER PTHR30636 1 293 1.1E-85 T 22-04-2016 HRM2_RS09960 bb8402a0a1bc8fea7c7493fc4b5fcdbd 63 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 37 50 - T 22-04-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 HRM2_RS09960 bb8402a0a1bc8fea7c7493fc4b5fcdbd 63 PANTHER PTHR10314 7 61 2.0E-22 T 22-04-2016 HRM2_RS09960 bb8402a0a1bc8fea7c7493fc4b5fcdbd 63 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 35 53 - T 22-04-2016 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 HRM2_RS09960 bb8402a0a1bc8fea7c7493fc4b5fcdbd 63 Gene3D G3DSA:3.40.50.1100 45 63 5.1E-7 T 22-04-2016 HRM2_RS09960 bb8402a0a1bc8fea7c7493fc4b5fcdbd 63 PANTHER PTHR10314:SF56 7 61 2.0E-22 T 22-04-2016 HRM2_RS09960 bb8402a0a1bc8fea7c7493fc4b5fcdbd 63 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 11 60 1.4E-13 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HRM2_RS09960 bb8402a0a1bc8fea7c7493fc4b5fcdbd 63 SUPERFAMILY SSF53686 6 62 4.06E-17 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HRM2_RS09960 bb8402a0a1bc8fea7c7493fc4b5fcdbd 63 Gene3D G3DSA:3.40.50.1100 5 44 1.5E-14 T 22-04-2016 HRM2_RS10910 60ac893c3b7113240e4e8756b0eefbe3 151 SMART SM00344 4 104 0.0054 T 22-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 HRM2_RS10910 60ac893c3b7113240e4e8756b0eefbe3 151 Pfam PF13404 AsnC-type helix-turn-helix domain 4 48 8.6E-8 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 HRM2_RS10910 60ac893c3b7113240e4e8756b0eefbe3 151 PANTHER PTHR30154:SF21 1 151 1.1E-42 T 22-04-2016 HRM2_RS10910 60ac893c3b7113240e4e8756b0eefbe3 151 SUPERFAMILY SSF46785 3 67 4.93E-7 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS10910 60ac893c3b7113240e4e8756b0eefbe3 151 Gene3D G3DSA:1.10.10.10 1 56 1.9E-11 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS10910 60ac893c3b7113240e4e8756b0eefbe3 151 ProSitePatterns PS00519 AsnC-type HTH domain signature. 25 51 - T 22-04-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site HRM2_RS10910 60ac893c3b7113240e4e8756b0eefbe3 151 PANTHER PTHR30154 1 151 1.1E-42 T 22-04-2016 HRM2_RS03570 51ec4af8c006618bec5a1d75401c54e0 284 Gene3D G3DSA:1.10.10.10 224 273 4.5E-16 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS03570 51ec4af8c006618bec5a1d75401c54e0 284 PANTHER PTHR24423:SF552 9 141 5.9E-13 T 22-04-2016 HRM2_RS03570 51ec4af8c006618bec5a1d75401c54e0 284 PANTHER PTHR24423:SF552 171 180 5.9E-13 T 22-04-2016 HRM2_RS03570 51ec4af8c006618bec5a1d75401c54e0 284 SUPERFAMILY SSF46894 212 273 1.67E-15 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HRM2_RS03570 51ec4af8c006618bec5a1d75401c54e0 284 PANTHER PTHR24423 9 141 5.9E-13 T 22-04-2016 HRM2_RS03570 51ec4af8c006618bec5a1d75401c54e0 284 PANTHER PTHR24423 171 180 5.9E-13 T 22-04-2016 HRM2_RS03570 51ec4af8c006618bec5a1d75401c54e0 284 ProSitePatterns PS00622 LuxR-type HTH domain signature. 239 266 - T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS03570 51ec4af8c006618bec5a1d75401c54e0 284 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 239 255 5.9E-10 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS03570 51ec4af8c006618bec5a1d75401c54e0 284 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 225 239 5.9E-10 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS03570 51ec4af8c006618bec5a1d75401c54e0 284 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 255 267 5.9E-10 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS03570 51ec4af8c006618bec5a1d75401c54e0 284 Gene3D G3DSA:3.30.450.20 4 124 4.4E-7 T 22-04-2016 HRM2_RS03570 51ec4af8c006618bec5a1d75401c54e0 284 SMART SM00421 222 279 3.7E-13 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS03570 51ec4af8c006618bec5a1d75401c54e0 284 Pfam PF00196 Bacterial regulatory proteins, luxR family 224 273 4.0E-15 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS07930 ae32b7f9ed1cedaadf4b1571cc8cfd4b 408 Gene3D G3DSA:3.40.50.360 260 399 1.2E-35 T 22-04-2016 IPR029039 Flavoprotein-like domain HRM2_RS07930 ae32b7f9ed1cedaadf4b1571cc8cfd4b 408 Gene3D G3DSA:3.60.15.10 1 252 3.2E-71 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS07930 ae32b7f9ed1cedaadf4b1571cc8cfd4b 408 PANTHER PTHR32145 1 405 2.9E-99 T 22-04-2016 HRM2_RS07930 ae32b7f9ed1cedaadf4b1571cc8cfd4b 408 Pfam PF00753 Metallo-beta-lactamase superfamily 35 177 1.2E-6 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS07930 ae32b7f9ed1cedaadf4b1571cc8cfd4b 408 PIRSF PIRSF005243 1 406 5.8E-108 T 22-04-2016 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 HRM2_RS07930 ae32b7f9ed1cedaadf4b1571cc8cfd4b 408 SUPERFAMILY SSF52218 262 399 2.1E-26 T 22-04-2016 IPR029039 Flavoprotein-like domain HRM2_RS07930 ae32b7f9ed1cedaadf4b1571cc8cfd4b 408 SMART SM00849 35 233 7.4E-25 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS07930 ae32b7f9ed1cedaadf4b1571cc8cfd4b 408 PANTHER PTHR32145:SF2 1 405 2.9E-99 T 22-04-2016 HRM2_RS07930 ae32b7f9ed1cedaadf4b1571cc8cfd4b 408 SUPERFAMILY SSF56281 3 292 7.99E-46 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS02250 25f41aae89da9d1f77500793dbc32d12 363 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 49 177 2.6E-48 T 22-04-2016 IPR006261 Deoxyguanosinetriphosphate triphosphohydrolase GO:0000287|GO:0008832|GO:0046039 HRM2_RS02250 25f41aae89da9d1f77500793dbc32d12 363 PANTHER PTHR11373:SF25 15 353 1.3E-82 T 22-04-2016 HRM2_RS02250 25f41aae89da9d1f77500793dbc32d12 363 SMART SM00471 83 217 2.9E-11 T 22-04-2016 IPR003607 HD/PDEase domain HRM2_RS02250 25f41aae89da9d1f77500793dbc32d12 363 Pfam PF13286 Phosphohydrolase-associated domain 263 355 9.7E-24 T 22-04-2016 IPR026875 Phosphohydrolase-associated domain HRM2_RS02250 25f41aae89da9d1f77500793dbc32d12 363 PANTHER PTHR11373 15 353 1.3E-82 T 22-04-2016 HRM2_RS02250 25f41aae89da9d1f77500793dbc32d12 363 Pfam PF01966 HD domain 87 206 2.2E-15 T 22-04-2016 IPR006674 HD domain HRM2_RS02250 25f41aae89da9d1f77500793dbc32d12 363 Gene3D G3DSA:1.10.3210.10 47 359 1.2E-72 T 22-04-2016 IPR006674 HD domain HRM2_RS02250 25f41aae89da9d1f77500793dbc32d12 363 SUPERFAMILY SSF109604 39 360 1.47E-72 T 22-04-2016 HRM2_RS09835 561841dac92774f6626d86d54929b19b 332 Gene3D G3DSA:3.40.630.30 121 277 4.4E-36 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS09835 561841dac92774f6626d86d54929b19b 332 SUPERFAMILY SSF55729 132 287 9.53E-34 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS09835 561841dac92774f6626d86d54929b19b 332 Pfam PF13480 Acetyltransferase (GNAT) domain 139 270 3.6E-13 T 22-04-2016 HRM2_RS09835 561841dac92774f6626d86d54929b19b 332 TIGRFAM TIGR03019 pepcterm_femAB: FemAB-related protein, PEP-CTERM system-associated 1 330 1.5E-84 T 22-04-2016 IPR017469 PEP-CTERM system-associated, FemAB-related HRM2_RS13655 38c4f02ea735d80276dc6d4d8d6c1ed9 453 Gene3D G3DSA:3.40.50.300 183 226 7.8E-4 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13655 38c4f02ea735d80276dc6d4d8d6c1ed9 453 PANTHER PTHR11262 228 453 6.0E-196 T 22-04-2016 HRM2_RS13655 38c4f02ea735d80276dc6d4d8d6c1ed9 453 PANTHER PTHR11262 1 105 6.0E-196 T 22-04-2016 HRM2_RS13655 38c4f02ea735d80276dc6d4d8d6c1ed9 453 PANTHER PTHR11262:SF3 228 453 6.0E-196 T 22-04-2016 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 HRM2_RS13655 38c4f02ea735d80276dc6d4d8d6c1ed9 453 PANTHER PTHR11262:SF3 1 105 6.0E-196 T 22-04-2016 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 HRM2_RS13655 38c4f02ea735d80276dc6d4d8d6c1ed9 453 SMART SM00382 49 342 1.6E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS13655 38c4f02ea735d80276dc6d4d8d6c1ed9 453 Gene3D G3DSA:1.10.8.60 345 453 1.1E-37 T 22-04-2016 HRM2_RS13655 38c4f02ea735d80276dc6d4d8d6c1ed9 453 Gene3D G3DSA:3.40.50.300 255 341 3.6E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13655 38c4f02ea735d80276dc6d4d8d6c1ed9 453 Gene3D G3DSA:3.40.50.300 5 110 3.6E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13655 38c4f02ea735d80276dc6d4d8d6c1ed9 453 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 1 453 42.553 T 22-04-2016 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 HRM2_RS13655 38c4f02ea735d80276dc6d4d8d6c1ed9 453 Gene3D G3DSA:1.10.8.10 112 182 5.6E-28 T 22-04-2016 HRM2_RS13655 38c4f02ea735d80276dc6d4d8d6c1ed9 453 Gene3D G3DSA:1.10.8.10 227 253 5.6E-28 T 22-04-2016 HRM2_RS13655 38c4f02ea735d80276dc6d4d8d6c1ed9 453 SUPERFAMILY SSF52540 4 451 1.14E-89 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13655 38c4f02ea735d80276dc6d4d8d6c1ed9 453 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 53 102 6.5E-6 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HRM2_RS13655 38c4f02ea735d80276dc6d4d8d6c1ed9 453 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 345 420 1.5E-7 T 22-04-2016 IPR019489 Clp ATPase, C-terminal HRM2_RS13655 38c4f02ea735d80276dc6d4d8d6c1ed9 453 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 5 453 8.2E-195 T 22-04-2016 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 HRM2_RS13655 38c4f02ea735d80276dc6d4d8d6c1ed9 453 Pfam PF07724 AAA domain (Cdc48 subfamily) 199 339 6.3E-41 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HRM2_RS13655 38c4f02ea735d80276dc6d4d8d6c1ed9 453 SMART SM01086 345 441 4.1E-24 T 22-04-2016 IPR019489 Clp ATPase, C-terminal HRM2_RS13985 0489b40b45bde86bda72208595457a2e 236 SUPERFAMILY SSF48008 98 233 1.54E-27 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS13985 0489b40b45bde86bda72208595457a2e 236 Pfam PF07729 FCD domain 100 224 6.3E-28 T 22-04-2016 IPR011711 GntR, C-terminal HRM2_RS13985 0489b40b45bde86bda72208595457a2e 236 Gene3D G3DSA:1.10.10.10 8 81 4.9E-25 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS13985 0489b40b45bde86bda72208595457a2e 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 1.1E-6 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS13985 0489b40b45bde86bda72208595457a2e 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 1.1E-6 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS13985 0489b40b45bde86bda72208595457a2e 236 Gene3D G3DSA:1.20.120.530 97 233 3.6E-28 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS13985 0489b40b45bde86bda72208595457a2e 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 1.4E-18 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS13985 0489b40b45bde86bda72208595457a2e 236 SUPERFAMILY SSF46785 6 80 1.86E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS13985 0489b40b45bde86bda72208595457a2e 236 SMART SM00895 100 226 9.3E-24 T 22-04-2016 IPR011711 GntR, C-terminal HRM2_RS13985 0489b40b45bde86bda72208595457a2e 236 PANTHER PTHR11751 14 116 1.4E-30 T 22-04-2016 HRM2_RS13985 0489b40b45bde86bda72208595457a2e 236 SMART SM00345 17 76 1.9E-18 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS21260 04946ee83fec637af18058a746935e71 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 5.7E-11 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS21260 04946ee83fec637af18058a746935e71 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 5.7E-11 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS21260 04946ee83fec637af18058a746935e71 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 5.7E-11 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS21260 04946ee83fec637af18058a746935e71 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 5.7E-11 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS21260 04946ee83fec637af18058a746935e71 144 Pfam PF01047 MarR family 35 91 9.2E-11 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS21260 04946ee83fec637af18058a746935e71 144 Gene3D G3DSA:1.10.10.10 7 142 4.8E-31 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS21260 04946ee83fec637af18058a746935e71 144 PANTHER PTHR33164 25 144 1.5E-21 T 22-04-2016 HRM2_RS21260 04946ee83fec637af18058a746935e71 144 SMART SM00347 27 127 2.0E-20 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS21260 04946ee83fec637af18058a746935e71 144 SUPERFAMILY SSF46785 6 142 2.04E-28 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS15315 27b134cd58ecca14d711270e6d9c4fca 441 Pfam PF00448 SRP54-type protein, GTPase domain 101 295 1.6E-71 T 22-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 HRM2_RS15315 27b134cd58ecca14d711270e6d9c4fca 441 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 426 7.4E-175 T 22-04-2016 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 HRM2_RS15315 27b134cd58ecca14d711270e6d9c4fca 441 SUPERFAMILY SSF52540 42 352 9.14E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS15315 27b134cd58ecca14d711270e6d9c4fca 441 Gene3D G3DSA:1.20.120.140 2 88 9.5E-31 T 22-04-2016 HRM2_RS15315 27b134cd58ecca14d711270e6d9c4fca 441 Pfam PF02978 Signal peptide binding domain 326 424 1.4E-31 T 22-04-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 HRM2_RS15315 27b134cd58ecca14d711270e6d9c4fca 441 SMART SM00382 99 269 1.3E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS15315 27b134cd58ecca14d711270e6d9c4fca 441 SMART SM00962 100 295 1.2E-102 T 22-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 HRM2_RS15315 27b134cd58ecca14d711270e6d9c4fca 441 SMART SM00963 1 86 1.0E-30 T 22-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 HRM2_RS15315 27b134cd58ecca14d711270e6d9c4fca 441 SUPERFAMILY SSF47446 326 428 3.92E-33 T 22-04-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 HRM2_RS15315 27b134cd58ecca14d711270e6d9c4fca 441 PANTHER PTHR11564 1 432 6.6E-240 T 22-04-2016 HRM2_RS15315 27b134cd58ecca14d711270e6d9c4fca 441 Gene3D G3DSA:3.40.50.300 97 296 2.9E-73 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS15315 27b134cd58ecca14d711270e6d9c4fca 441 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 268 281 - T 22-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 HRM2_RS15315 27b134cd58ecca14d711270e6d9c4fca 441 Pfam PF02881 SRP54-type protein, helical bundle domain 5 81 8.8E-22 T 22-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 HRM2_RS15315 27b134cd58ecca14d711270e6d9c4fca 441 PANTHER PTHR11564:SF7 1 432 6.6E-240 T 22-04-2016 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 HRM2_RS15315 27b134cd58ecca14d711270e6d9c4fca 441 Gene3D G3DSA:1.10.260.30 326 429 1.9E-36 T 22-04-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 HRM2_RS15315 27b134cd58ecca14d711270e6d9c4fca 441 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 439 32.98 T 22-04-2016 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 HRM2_RS13185 0c3183e0e20d31040f5b044ece2e181c 345 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 339 41.962 T 22-04-2016 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HRM2_RS13185 0c3183e0e20d31040f5b044ece2e181c 345 PANTHER PTHR32338:SF8 1 342 3.1E-169 T 22-04-2016 HRM2_RS13185 0c3183e0e20d31040f5b044ece2e181c 345 PANTHER PTHR32338 1 342 3.1E-169 T 22-04-2016 HRM2_RS13185 0c3183e0e20d31040f5b044ece2e181c 345 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 139 1.8E-32 T 22-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 HRM2_RS13185 0c3183e0e20d31040f5b044ece2e181c 345 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 2 341 2.5E-129 T 22-04-2016 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HRM2_RS13185 0c3183e0e20d31040f5b044ece2e181c 345 SMART SM00859 3 141 2.4E-46 T 22-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 HRM2_RS13185 0c3183e0e20d31040f5b044ece2e181c 345 SUPERFAMILY SSF51735 2 170 1.63E-47 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS13185 0c3183e0e20d31040f5b044ece2e181c 345 Gene3D G3DSA:3.30.360.10 158 313 4.7E-61 T 22-04-2016 HRM2_RS13185 0c3183e0e20d31040f5b044ece2e181c 345 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 158 316 5.1E-20 T 22-04-2016 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HRM2_RS13185 0c3183e0e20d31040f5b044ece2e181c 345 Gene3D G3DSA:3.40.50.720 1 157 1.5E-59 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS13185 0c3183e0e20d31040f5b044ece2e181c 345 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 144 160 - T 22-04-2016 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HRM2_RS13185 0c3183e0e20d31040f5b044ece2e181c 345 SUPERFAMILY SSF55347 149 313 1.57E-53 T 22-04-2016 HRM2_RS19750 9f22961e5b83bdb796d86f17a40feaf4 127 SMART SM00448 4 114 1.2E-32 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS19750 9f22961e5b83bdb796d86f17a40feaf4 127 Gene3D G3DSA:3.40.50.2300 5 125 4.9E-34 T 22-04-2016 HRM2_RS19750 9f22961e5b83bdb796d86f17a40feaf4 127 Pfam PF00072 Response regulator receiver domain 7 113 3.1E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS19750 9f22961e5b83bdb796d86f17a40feaf4 127 PANTHER PTHR26402 4 124 3.7E-36 T 22-04-2016 HRM2_RS19750 9f22961e5b83bdb796d86f17a40feaf4 127 SUPERFAMILY SSF52172 4 125 4.7E-36 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS12660 9a1cd0c121dd677bc790b9de02c9029b 480 Pfam PF02397 Bacterial sugar transferase 286 475 1.1E-54 T 22-04-2016 IPR003362 Bacterial sugar transferase HRM2_RS12660 9a1cd0c121dd677bc790b9de02c9029b 480 PANTHER PTHR30576 6 479 1.5E-107 T 22-04-2016 HRM2_RS12660 9a1cd0c121dd677bc790b9de02c9029b 480 PANTHER PTHR30576:SF4 6 479 1.5E-107 T 22-04-2016 HRM2_RS12660 9a1cd0c121dd677bc790b9de02c9029b 480 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 17 479 2.0E-119 T 22-04-2016 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase HRM2_RS12660 9a1cd0c121dd677bc790b9de02c9029b 480 Pfam PF13727 CoA-binding domain 67 244 3.0E-26 T 22-04-2016 HRM2_RS09115 25ce82cf2a61f527a7933d73155728b4 585 Pfam PF00664 ABC transporter transmembrane region 29 296 1.5E-55 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HRM2_RS09115 25ce82cf2a61f527a7933d73155728b4 585 PANTHER PTHR24221 16 583 9.8E-234 T 22-04-2016 HRM2_RS09115 25ce82cf2a61f527a7933d73155728b4 585 Pfam PF00005 ABC transporter 361 510 3.0E-32 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS09115 25ce82cf2a61f527a7933d73155728b4 585 Gene3D G3DSA:1.20.1560.10 17 325 3.2E-84 T 22-04-2016 HRM2_RS09115 25ce82cf2a61f527a7933d73155728b4 585 SUPERFAMILY SSF90123 16 330 3.79E-82 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HRM2_RS09115 25ce82cf2a61f527a7933d73155728b4 585 ProSitePatterns PS00211 ABC transporters family signature. 482 496 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS09115 25ce82cf2a61f527a7933d73155728b4 585 SMART SM00382 370 556 1.5E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS09115 25ce82cf2a61f527a7933d73155728b4 585 SUPERFAMILY SSF52540 336 581 1.93E-91 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09115 25ce82cf2a61f527a7933d73155728b4 585 Gene3D G3DSA:3.40.50.300 344 575 2.3E-81 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01590 3ce627be15d0be47ee5995b0b8354e44 678 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 13 338 1.8E-82 T 22-04-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 HRM2_RS01590 3ce627be15d0be47ee5995b0b8354e44 678 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 384 403 7.7E-12 T 22-04-2016 HRM2_RS01590 3ce627be15d0be47ee5995b0b8354e44 678 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 505 523 7.7E-12 T 22-04-2016 HRM2_RS01590 3ce627be15d0be47ee5995b0b8354e44 678 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 466 484 7.7E-12 T 22-04-2016 HRM2_RS01590 3ce627be15d0be47ee5995b0b8354e44 678 PANTHER PTHR22893:SF25 1 424 2.9E-236 T 22-04-2016 HRM2_RS01590 3ce627be15d0be47ee5995b0b8354e44 678 SUPERFAMILY SSF51395 9 369 8.18E-107 T 22-04-2016 HRM2_RS01590 3ce627be15d0be47ee5995b0b8354e44 678 Gene3D G3DSA:3.50.50.60 478 633 6.3E-42 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS01590 3ce627be15d0be47ee5995b0b8354e44 678 Gene3D G3DSA:3.50.50.60 367 473 4.7E-26 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS01590 3ce627be15d0be47ee5995b0b8354e44 678 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 382 658 2.5E-23 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS01590 3ce627be15d0be47ee5995b0b8354e44 678 PANTHER PTHR22893 1 424 2.9E-236 T 22-04-2016 HRM2_RS01590 3ce627be15d0be47ee5995b0b8354e44 678 SUPERFAMILY SSF51905 469 526 9.91E-18 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS01590 3ce627be15d0be47ee5995b0b8354e44 678 SUPERFAMILY SSF51905 564 654 9.91E-18 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS01590 3ce627be15d0be47ee5995b0b8354e44 678 Gene3D G3DSA:3.20.20.70 10 366 5.0E-116 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS01590 3ce627be15d0be47ee5995b0b8354e44 678 SUPERFAMILY SSF51971 340 526 6.12E-40 T 22-04-2016 HRM2_RS09425 0fe5fd37f0a494b5a2d186d48ed330c3 459 Pfam PF05140 ResB-like family 21 346 6.6E-90 T 22-04-2016 IPR007816 ResB-like domain HRM2_RS09425 0fe5fd37f0a494b5a2d186d48ed330c3 459 Pfam PF05140 ResB-like family 364 444 3.0E-15 T 22-04-2016 IPR007816 ResB-like domain HRM2_RS09425 0fe5fd37f0a494b5a2d186d48ed330c3 459 PANTHER PTHR31566:SF0 14 457 2.0E-65 T 22-04-2016 HRM2_RS09425 0fe5fd37f0a494b5a2d186d48ed330c3 459 PANTHER PTHR31566 14 457 2.0E-65 T 22-04-2016 HRM2_RS16035 2fe94beeb8df0fdead72723358b9f5c7 382 PANTHER PTHR24023:SF577 26 370 9.2E-54 T 22-04-2016 HRM2_RS16035 2fe94beeb8df0fdead72723358b9f5c7 382 Gene3D G3DSA:3.40.50.10540 4 207 1.5E-107 T 22-04-2016 IPR023606 CoA-transferase family III domain HRM2_RS16035 2fe94beeb8df0fdead72723358b9f5c7 382 Gene3D G3DSA:3.40.50.10540 292 382 1.5E-107 T 22-04-2016 IPR023606 CoA-transferase family III domain HRM2_RS16035 2fe94beeb8df0fdead72723358b9f5c7 382 SUPERFAMILY SSF89796 5 382 1.11E-121 T 22-04-2016 IPR023606 CoA-transferase family III domain HRM2_RS16035 2fe94beeb8df0fdead72723358b9f5c7 382 Pfam PF02515 CoA-transferase family III 7 355 2.6E-105 T 22-04-2016 IPR003673 CoA-transferase family III GO:0003824 HRM2_RS16035 2fe94beeb8df0fdead72723358b9f5c7 382 PANTHER PTHR24023 26 370 9.2E-54 T 22-04-2016 HRM2_RS16035 2fe94beeb8df0fdead72723358b9f5c7 382 Gene3D G3DSA:3.30.1540.10 216 291 1.4E-12 T 22-04-2016 HRM2_RS15935 6f7f2b1dc37742c4d5e5ce6cfa0b869c 430 Pfam PF07690 Major Facilitator Superfamily 21 278 2.6E-28 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS15935 6f7f2b1dc37742c4d5e5ce6cfa0b869c 430 Gene3D G3DSA:1.20.1250.20 229 425 4.5E-16 T 22-04-2016 HRM2_RS15935 6f7f2b1dc37742c4d5e5ce6cfa0b869c 430 PIRSF PIRSF002808 2 416 7.1E-35 T 22-04-2016 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 HRM2_RS15935 6f7f2b1dc37742c4d5e5ce6cfa0b869c 430 SUPERFAMILY SSF103473 7 422 2.62E-61 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS15935 6f7f2b1dc37742c4d5e5ce6cfa0b869c 430 ProSitePatterns PS00216 Sugar transport proteins signature 1. 286 303 - T 22-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 HRM2_RS15935 6f7f2b1dc37742c4d5e5ce6cfa0b869c 430 PANTHER PTHR23512 2 430 2.5E-83 T 22-04-2016 HRM2_RS15935 6f7f2b1dc37742c4d5e5ce6cfa0b869c 430 PANTHER PTHR23512:SF1 2 430 2.5E-83 T 22-04-2016 HRM2_RS15935 6f7f2b1dc37742c4d5e5ce6cfa0b869c 430 Gene3D G3DSA:1.20.1250.20 12 204 1.2E-32 T 22-04-2016 HRM2_RS10395 ce27fada8cd986c8f605060139312b54 556 SUPERFAMILY SSF143975 1 374 6.54E-139 T 22-04-2016 HRM2_RS10395 ce27fada8cd986c8f605060139312b54 556 PANTHER PTHR21000 1 555 1.1E-304 T 22-04-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HRM2_RS10395 ce27fada8cd986c8f605060139312b54 556 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 119 129 - T 22-04-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HRM2_RS10395 ce27fada8cd986c8f605060139312b54 556 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 1 555 46.906 T 22-04-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HRM2_RS10395 ce27fada8cd986c8f605060139312b54 556 Pfam PF00920 Dehydratase family 31 552 1.0E-220 T 22-04-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HRM2_RS10395 ce27fada8cd986c8f605060139312b54 556 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 463 474 - T 22-04-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HRM2_RS10395 ce27fada8cd986c8f605060139312b54 556 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 14 555 1.1E-236 T 22-04-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HRM2_RS10395 ce27fada8cd986c8f605060139312b54 556 PANTHER PTHR21000:SF11 1 555 1.1E-304 T 22-04-2016 HRM2_RS10395 ce27fada8cd986c8f605060139312b54 556 SUPERFAMILY SSF52016 375 554 1.57E-59 T 22-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel HRM2_RS06175 0ac32a310e329422adeaf5dbf808b7ed 302 PANTHER PTHR22908:SF67 6 289 9.1E-70 T 22-04-2016 HRM2_RS06175 0ac32a310e329422adeaf5dbf808b7ed 302 SMART SM00382 34 212 1.3E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS06175 0ac32a310e329422adeaf5dbf808b7ed 302 PANTHER PTHR22908 6 289 9.1E-70 T 22-04-2016 HRM2_RS06175 0ac32a310e329422adeaf5dbf808b7ed 302 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 38 203 8.8E-11 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HRM2_RS06175 0ac32a310e329422adeaf5dbf808b7ed 302 SUPERFAMILY SSF52540 125 290 4.87E-37 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06175 0ac32a310e329422adeaf5dbf808b7ed 302 SUPERFAMILY SSF52540 22 78 4.87E-37 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06175 0ac32a310e329422adeaf5dbf808b7ed 302 Gene3D G3DSA:3.40.50.300 123 235 5.8E-31 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06175 0ac32a310e329422adeaf5dbf808b7ed 302 Gene3D G3DSA:3.40.50.300 23 82 5.8E-31 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20580 b19134d0fbbbece213e205e8af3d5ff9 384 SUPERFAMILY SSF54862 142 294 5.93E-27 T 22-04-2016 HRM2_RS20580 b19134d0fbbbece213e205e8af3d5ff9 384 PANTHER PTHR24960:SF35 1 351 1.4E-105 T 22-04-2016 HRM2_RS20580 b19134d0fbbbece213e205e8af3d5ff9 384 Pfam PF12838 4Fe-4S dicluster domain 195 238 2.7E-11 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS20580 b19134d0fbbbece213e205e8af3d5ff9 384 PANTHER PTHR24960 1 351 1.4E-105 T 22-04-2016 HRM2_RS20580 b19134d0fbbbece213e205e8af3d5ff9 384 Pfam PF04015 Domain of unknown function (DUF362) 42 314 1.7E-40 T 22-04-2016 IPR007160 Domain of unknown function DUF362 HRM2_RS20580 b19134d0fbbbece213e205e8af3d5ff9 384 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 225 236 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS20580 b19134d0fbbbece213e205e8af3d5ff9 384 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 196 207 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS20580 b19134d0fbbbece213e205e8af3d5ff9 384 Gene3D G3DSA:3.30.70.20 176 246 1.3E-18 T 22-04-2016 HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 SUPERFAMILY SSF54980 400 478 1.12E-23 T 22-04-2016 IPR009022 Elongation factor G, III-V domain HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 Pfam PF14492 Elongation Factor G, domain II 404 476 2.4E-31 T 22-04-2016 IPR009022 Elongation factor G, III-V domain HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 Pfam PF03764 Elongation factor G, domain IV 477 596 7.9E-27 T 22-04-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 SUPERFAMILY SSF50447 304 400 1.04E-29 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 SUPERFAMILY SSF50447 248 274 1.04E-29 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 676 1.1E-279 T 22-04-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 179 5.0E-31 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 PRINTS PR00315 GTP-binding elongation factor signature 58 66 2.0E-14 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 PRINTS PR00315 GTP-binding elongation factor signature 78 88 2.0E-14 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 PRINTS PR00315 GTP-binding elongation factor signature 12 25 2.0E-14 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 PRINTS PR00315 GTP-binding elongation factor signature 130 139 2.0E-14 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 PRINTS PR00315 GTP-binding elongation factor signature 94 105 2.0E-14 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 SUPERFAMILY SSF54980 599 676 1.58E-22 T 22-04-2016 IPR009022 Elongation factor G, III-V domain HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 PANTHER PTHR23115:SF66 302 677 4.3E-280 T 22-04-2016 HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 PANTHER PTHR23115:SF66 1 177 4.3E-280 T 22-04-2016 HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 PANTHER PTHR23115:SF66 254 282 4.3E-280 T 22-04-2016 HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 SMART SM00838 598 677 6.6E-33 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 Pfam PF00679 Elongation factor G C-terminus 599 676 2.7E-25 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 Pfam PF03144 Elongation factor Tu domain 2 324 389 6.6E-13 T 22-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 Gene3D G3DSA:3.30.230.10 482 600 3.3E-35 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 Gene3D G3DSA:2.40.30.10 307 402 2.2E-28 T 22-04-2016 HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 PANTHER PTHR23115 302 677 4.3E-280 T 22-04-2016 HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 PANTHER PTHR23115 1 177 4.3E-280 T 22-04-2016 HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 PANTHER PTHR23115 254 282 4.3E-280 T 22-04-2016 HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 SMART SM00889 478 596 1.0E-39 T 22-04-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 Gene3D G3DSA:3.40.50.300 6 286 1.0E-102 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 Hamap MF_00054_B Elongation factor G [fusA]. 6 677 95.525 T 22-04-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 Pfam PF00009 Elongation factor Tu GTP binding domain 8 281 5.1E-68 T 22-04-2016 HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 SUPERFAMILY SSF54211 477 596 3.75E-32 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 Gene3D G3DSA:3.30.70.870 404 478 3.2E-33 T 22-04-2016 HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 SUPERFAMILY SSF52540 6 281 1.07E-103 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 Gene3D G3DSA:3.30.70.240 601 676 1.1E-26 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain HRM2_RS15725 0c96019f7ee1e1ae0dcafd9cb7f3b80f 677 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 22-04-2016 IPR031157 Tr-type G domain, conserved site HRM2_RS06455 e95540c1648885ea4eed5569635cd619 454 SMART SM00924 30 133 3.3E-27 T 22-04-2016 IPR006668 Magnesium transporter, MgtE intracellular domain HRM2_RS06455 e95540c1648885ea4eed5569635cd619 454 Pfam PF01769 Divalent cation transporter 320 441 2.1E-24 T 22-04-2016 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 HRM2_RS06455 e95540c1648885ea4eed5569635cd619 454 TIGRFAM TIGR00400 mgtE: magnesium transporter 15 448 2.7E-90 T 22-04-2016 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 HRM2_RS06455 e95540c1648885ea4eed5569635cd619 454 SUPERFAMILY SSF54631 133 271 8.21E-22 T 22-04-2016 HRM2_RS06455 e95540c1648885ea4eed5569635cd619 454 Pfam PF00571 CBS domain 135 191 0.0053 T 22-04-2016 IPR000644 CBS domain HRM2_RS06455 e95540c1648885ea4eed5569635cd619 454 Pfam PF00571 CBS domain 200 246 4.9E-7 T 22-04-2016 IPR000644 CBS domain HRM2_RS06455 e95540c1648885ea4eed5569635cd619 454 SUPERFAMILY SSF161093 283 448 1.31E-41 T 22-04-2016 HRM2_RS06455 e95540c1648885ea4eed5569635cd619 454 SUPERFAMILY SSF158791 8 130 2.75E-27 T 22-04-2016 HRM2_RS06455 e95540c1648885ea4eed5569635cd619 454 Pfam PF03448 MgtE intracellular N domain 30 131 1.1E-23 T 22-04-2016 IPR006668 Magnesium transporter, MgtE intracellular domain HRM2_RS06455 e95540c1648885ea4eed5569635cd619 454 PANTHER PTHR41394 8 448 5.2E-35 T 22-04-2016 HRM2_RS06455 e95540c1648885ea4eed5569635cd619 454 Gene3D G3DSA:1.25.60.10 8 126 2.1E-28 T 22-04-2016 HRM2_RS06455 e95540c1648885ea4eed5569635cd619 454 Gene3D G3DSA:3.10.580.10 127 257 6.0E-17 T 22-04-2016 HRM2_RS06455 e95540c1648885ea4eed5569635cd619 454 Gene3D G3DSA:1.10.357.20 284 448 4.9E-45 T 22-04-2016 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 HRM2_RS18440 8a377105c248bf5b7bc52e43292a1c8f 153 Pfam PF13690 Chemotaxis phosphatase CheX 42 138 7.0E-26 T 22-04-2016 IPR028051 Chemotaxis phosphatase CheX-like domain KEGG: 00231+3.-.-.-|KEGG: 00563+3.-.-.-|KEGG: 00983+3.-.-.- HRM2_RS18440 8a377105c248bf5b7bc52e43292a1c8f 153 SUPERFAMILY SSF103039 1 152 4.58E-35 T 22-04-2016 IPR028976 CheC-like domain HRM2_RS18440 8a377105c248bf5b7bc52e43292a1c8f 153 Gene3D G3DSA:3.40.1550.10 1 152 5.1E-41 T 22-04-2016 IPR028976 CheC-like domain HRM2_RS18440 8a377105c248bf5b7bc52e43292a1c8f 153 PANTHER PTHR39452:SF1 1 153 9.7E-47 T 22-04-2016 HRM2_RS18440 8a377105c248bf5b7bc52e43292a1c8f 153 PANTHER PTHR39452 1 153 9.7E-47 T 22-04-2016 HRM2_RS16010 47526bd768d0ed0b73c785e6fca3b943 289 PRINTS PR01798 Succinyl-CoA synthase signature 241 258 1.2E-38 T 22-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 HRM2_RS16010 47526bd768d0ed0b73c785e6fca3b943 289 PRINTS PR01798 Succinyl-CoA synthase signature 209 222 1.2E-38 T 22-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 HRM2_RS16010 47526bd768d0ed0b73c785e6fca3b943 289 PRINTS PR01798 Succinyl-CoA synthase signature 178 196 1.2E-38 T 22-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 HRM2_RS16010 47526bd768d0ed0b73c785e6fca3b943 289 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 1.2E-38 T 22-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 HRM2_RS16010 47526bd768d0ed0b73c785e6fca3b943 289 Pfam PF02629 CoA binding domain 6 99 7.6E-28 T 22-04-2016 IPR003781 CoA-binding GO:0048037 HRM2_RS16010 47526bd768d0ed0b73c785e6fca3b943 289 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 287 2.0E-136 T 22-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 HRM2_RS16010 47526bd768d0ed0b73c785e6fca3b943 289 PIRSF PIRSF001553 1 289 5.9E-127 T 22-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 HRM2_RS16010 47526bd768d0ed0b73c785e6fca3b943 289 SUPERFAMILY SSF51735 2 122 8.1E-41 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS16010 47526bd768d0ed0b73c785e6fca3b943 289 Gene3D G3DSA:3.40.50.261 120 288 2.4E-70 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS16010 47526bd768d0ed0b73c785e6fca3b943 289 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 237 250 - T 22-04-2016 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site HRM2_RS16010 47526bd768d0ed0b73c785e6fca3b943 289 PANTHER PTHR11117:SF2 2 283 8.0E-171 T 22-04-2016 HRM2_RS16010 47526bd768d0ed0b73c785e6fca3b943 289 SUPERFAMILY SSF52210 123 279 1.44E-51 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS16010 47526bd768d0ed0b73c785e6fca3b943 289 Pfam PF00549 CoA-ligase 152 269 3.6E-18 T 22-04-2016 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS16010 47526bd768d0ed0b73c785e6fca3b943 289 PANTHER PTHR11117 2 283 8.0E-171 T 22-04-2016 HRM2_RS16010 47526bd768d0ed0b73c785e6fca3b943 289 Gene3D G3DSA:3.40.50.720 2 119 1.6E-55 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS16010 47526bd768d0ed0b73c785e6fca3b943 289 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 153 182 - T 22-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 HRM2_RS16010 47526bd768d0ed0b73c785e6fca3b943 289 SMART SM00881 4 100 4.4E-34 T 22-04-2016 IPR003781 CoA-binding GO:0048037 HRM2_RS10600 5db04c42caad461567b6aeafacdfb502 549 Gene3D G3DSA:1.10.101.10 215 294 3.2E-12 T 22-04-2016 IPR002477 Peptidoglycan binding-like HRM2_RS10600 5db04c42caad461567b6aeafacdfb502 549 SUPERFAMILY SSF47090 214 292 7.38E-10 T 22-04-2016 IPR002477 Peptidoglycan binding-like HRM2_RS10600 5db04c42caad461567b6aeafacdfb502 549 Pfam PF03734 L,D-transpeptidase catalytic domain 312 482 6.8E-33 T 22-04-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UniPathway: UPA00219 HRM2_RS10600 5db04c42caad461567b6aeafacdfb502 549 PANTHER PTHR41533 61 547 1.0E-94 T 22-04-2016 HRM2_RS10600 5db04c42caad461567b6aeafacdfb502 549 Pfam PF01471 Putative peptidoglycan binding domain 248 283 2.0E-4 T 22-04-2016 IPR002477 Peptidoglycan binding-like HRM2_RS10600 5db04c42caad461567b6aeafacdfb502 549 Gene3D G3DSA:2.40.440.10 426 475 1.5E-11 T 22-04-2016 HRM2_RS10600 5db04c42caad461567b6aeafacdfb502 549 Gene3D G3DSA:2.40.440.10 312 357 1.5E-11 T 22-04-2016 HRM2_RS10600 5db04c42caad461567b6aeafacdfb502 549 SUPERFAMILY SSF141523 424 474 3.79E-21 T 22-04-2016 HRM2_RS10600 5db04c42caad461567b6aeafacdfb502 549 SUPERFAMILY SSF141523 310 366 3.79E-21 T 22-04-2016 HRM2_RS10600 5db04c42caad461567b6aeafacdfb502 549 PANTHER PTHR41533:SF1 61 547 1.0E-94 T 22-04-2016 HRM2_RS12065 2e009602ed715d8e59c060c58a2481f9 650 PANTHER PTHR10357 47 398 2.8E-165 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 HRM2_RS12065 2e009602ed715d8e59c060c58a2481f9 650 PANTHER PTHR10357 453 608 2.8E-165 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 HRM2_RS12065 2e009602ed715d8e59c060c58a2481f9 650 Gene3D G3DSA:3.20.20.80 264 558 6.3E-93 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HRM2_RS12065 2e009602ed715d8e59c060c58a2481f9 650 Gene3D G3DSA:3.20.20.80 93 185 6.3E-93 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HRM2_RS12065 2e009602ed715d8e59c060c58a2481f9 650 SMART SM00642 99 556 3.5E-26 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HRM2_RS12065 2e009602ed715d8e59c060c58a2481f9 650 Pfam PF16657 Maltogenic Amylase, C-terminal domain 569 646 4.0E-8 T 22-04-2016 IPR032091 Maltogenic Amylase, C-terminal HRM2_RS12065 2e009602ed715d8e59c060c58a2481f9 650 SUPERFAMILY SSF51011 571 647 5.9E-8 T 22-04-2016 HRM2_RS12065 2e009602ed715d8e59c060c58a2481f9 650 PANTHER PTHR10357:SF122 47 398 2.8E-165 T 22-04-2016 HRM2_RS12065 2e009602ed715d8e59c060c58a2481f9 650 PANTHER PTHR10357:SF122 453 608 2.8E-165 T 22-04-2016 HRM2_RS12065 2e009602ed715d8e59c060c58a2481f9 650 Gene3D G3DSA:2.60.40.1180 568 648 1.3E-15 T 22-04-2016 IPR013780 Glycosyl hydrolase, all-beta HRM2_RS12065 2e009602ed715d8e59c060c58a2481f9 650 Gene3D G3DSA:3.90.400.10 186 256 1.6E-23 T 22-04-2016 HRM2_RS12065 2e009602ed715d8e59c060c58a2481f9 650 Pfam PF00128 Alpha amylase, catalytic domain 107 359 4.8E-41 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HRM2_RS12065 2e009602ed715d8e59c060c58a2481f9 650 SUPERFAMILY SSF51445 19 562 2.63E-115 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily HRM2_RS11595 6430262299c12977eda8481b71f30904 444 SMART SM00062 34 256 5.6E-16 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS11595 6430262299c12977eda8481b71f30904 444 PANTHER PTHR21666 261 440 2.9E-67 T 22-04-2016 HRM2_RS11595 6430262299c12977eda8481b71f30904 444 Gene3D G3DSA:3.40.190.10 113 196 7.5E-4 T 22-04-2016 HRM2_RS11595 6430262299c12977eda8481b71f30904 444 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 299 327 - T 22-04-2016 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 HRM2_RS11595 6430262299c12977eda8481b71f30904 444 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 49 254 6.2E-25 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS11595 6430262299c12977eda8481b71f30904 444 SUPERFAMILY SSF53955 422 443 1.09E-38 T 22-04-2016 IPR023346 Lysozyme-like domain HRM2_RS11595 6430262299c12977eda8481b71f30904 444 SUPERFAMILY SSF53955 257 387 1.09E-38 T 22-04-2016 IPR023346 Lysozyme-like domain HRM2_RS11595 6430262299c12977eda8481b71f30904 444 Gene3D G3DSA:1.10.530.10 419 442 1.9E-41 T 22-04-2016 HRM2_RS11595 6430262299c12977eda8481b71f30904 444 Gene3D G3DSA:1.10.530.10 248 384 1.9E-41 T 22-04-2016 HRM2_RS11595 6430262299c12977eda8481b71f30904 444 PANTHER PTHR21666:SF215 261 440 2.9E-67 T 22-04-2016 IPR023703 Membrane-bound lytic murein transglycosylase F GO:0016837 HRM2_RS11595 6430262299c12977eda8481b71f30904 444 SUPERFAMILY SSF53850 35 254 1.41E-33 T 22-04-2016 HRM2_RS11595 6430262299c12977eda8481b71f30904 444 Pfam PF01464 Transglycosylase SLT domain 282 390 5.5E-25 T 22-04-2016 IPR008258 Transglycosylase SLT domain 1 HRM2_RS11595 6430262299c12977eda8481b71f30904 444 Gene3D G3DSA:3.40.190.10 31 112 3.0E-17 T 22-04-2016 HRM2_RS11595 6430262299c12977eda8481b71f30904 444 Gene3D G3DSA:3.40.190.10 215 247 3.0E-17 T 22-04-2016 HRM2_RS24805 7a5269de1878aa0db252317a85e164c8 318 Gene3D G3DSA:3.40.50.300 4 226 1.1E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24805 7a5269de1878aa0db252317a85e164c8 318 SMART SM00382 27 213 4.7E-16 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS24805 7a5269de1878aa0db252317a85e164c8 318 PANTHER PTHR24220 4 237 1.4E-84 T 22-04-2016 HRM2_RS24805 7a5269de1878aa0db252317a85e164c8 318 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS24805 7a5269de1878aa0db252317a85e164c8 318 SUPERFAMILY SSF52540 4 235 1.37E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24805 7a5269de1878aa0db252317a85e164c8 318 Pfam PF00005 ABC transporter 18 156 5.2E-30 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS17840 d48a59895cc1a24bbd051be4eb4fd201 179 Gene3D G3DSA:3.30.1440.10 2 179 1.0E-76 T 22-04-2016 IPR022803 Ribosomal protein L5 domain HRM2_RS17840 d48a59895cc1a24bbd051be4eb4fd201 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 3.0E-40 T 22-04-2016 IPR031309 Ribosomal protein L5, C-terminal HRM2_RS17840 d48a59895cc1a24bbd051be4eb4fd201 179 SUPERFAMILY SSF55282 4 179 3.3E-76 T 22-04-2016 IPR022803 Ribosomal protein L5 domain HRM2_RS17840 d48a59895cc1a24bbd051be4eb4fd201 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 22-04-2016 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17840 d48a59895cc1a24bbd051be4eb4fd201 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 43.958 T 22-04-2016 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17840 d48a59895cc1a24bbd051be4eb4fd201 179 PANTHER PTHR11994 1 178 1.4E-91 T 22-04-2016 HRM2_RS17840 d48a59895cc1a24bbd051be4eb4fd201 179 Pfam PF00281 Ribosomal protein L5 24 80 1.8E-27 T 22-04-2016 IPR031310 Ribosomal protein L5, N-terminal HRM2_RS17840 d48a59895cc1a24bbd051be4eb4fd201 179 PIRSF PIRSF002161 1 179 3.1E-67 T 22-04-2016 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 HRM2_RS04875 146b43f3b5c744a4901672e0e2c35ef0 464 Gene3D G3DSA:1.10.10.60 400 453 7.1E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS04875 146b43f3b5c744a4901672e0e2c35ef0 464 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 172 185 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS04875 146b43f3b5c744a4901672e0e2c35ef0 464 SUPERFAMILY SSF52540 148 390 1.02E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04875 146b43f3b5c744a4901672e0e2c35ef0 464 PANTHER PTHR32071 131 463 1.4E-150 T 22-04-2016 HRM2_RS04875 146b43f3b5c744a4901672e0e2c35ef0 464 SUPERFAMILY SSF55785 15 124 2.79E-15 T 22-04-2016 IPR000014 PAS domain HRM2_RS04875 146b43f3b5c744a4901672e0e2c35ef0 464 Gene3D G3DSA:3.30.450.20 11 140 2.3E-16 T 22-04-2016 HRM2_RS04875 146b43f3b5c744a4901672e0e2c35ef0 464 Gene3D G3DSA:1.10.8.60 321 394 4.4E-22 T 22-04-2016 HRM2_RS04875 146b43f3b5c744a4901672e0e2c35ef0 464 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 433 453 1.2E-11 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS04875 146b43f3b5c744a4901672e0e2c35ef0 464 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 416 433 1.2E-11 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS04875 146b43f3b5c744a4901672e0e2c35ef0 464 Pfam PF13426 PAS domain 19 124 2.4E-14 T 22-04-2016 IPR000014 PAS domain HRM2_RS04875 146b43f3b5c744a4901672e0e2c35ef0 464 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 8 125 8.0E-11 T 22-04-2016 IPR000014 PAS domain HRM2_RS04875 146b43f3b5c744a4901672e0e2c35ef0 464 Pfam PF02954 Bacterial regulatory protein, Fis family 412 450 1.3E-12 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS04875 146b43f3b5c744a4901672e0e2c35ef0 464 Gene3D G3DSA:3.40.50.300 145 320 1.8E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04875 146b43f3b5c744a4901672e0e2c35ef0 464 SUPERFAMILY SSF46689 361 453 3.14E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS04875 146b43f3b5c744a4901672e0e2c35ef0 464 SMART SM00091 8 75 2.5E-5 T 22-04-2016 IPR000014 PAS domain HRM2_RS04875 146b43f3b5c744a4901672e0e2c35ef0 464 SMART SM00382 168 311 8.7E-5 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS04875 146b43f3b5c744a4901672e0e2c35ef0 464 Pfam PF00158 Sigma-54 interaction domain 149 315 5.6E-69 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS05140 d5b387ffbd06e2705d5958c73f22e8f8 469 Gene3D G3DSA:3.30.565.10 295 461 1.9E-37 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS05140 d5b387ffbd06e2705d5958c73f22e8f8 469 Pfam PF00512 His Kinase A (phospho-acceptor) domain 241 305 4.5E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS05140 d5b387ffbd06e2705d5958c73f22e8f8 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 402 3.6E-10 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS05140 d5b387ffbd06e2705d5958c73f22e8f8 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 416 3.6E-10 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS05140 d5b387ffbd06e2705d5958c73f22e8f8 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 441 3.6E-10 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS05140 d5b387ffbd06e2705d5958c73f22e8f8 469 SUPERFAMILY SSF158472 188 235 9.29E-9 T 22-04-2016 HRM2_RS05140 d5b387ffbd06e2705d5958c73f22e8f8 469 PANTHER PTHR24423 180 461 1.9E-66 T 22-04-2016 HRM2_RS05140 d5b387ffbd06e2705d5958c73f22e8f8 469 PANTHER PTHR24423 52 61 1.9E-66 T 22-04-2016 HRM2_RS05140 d5b387ffbd06e2705d5958c73f22e8f8 469 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 350 460 9.3E-21 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS05140 d5b387ffbd06e2705d5958c73f22e8f8 469 Gene3D G3DSA:1.10.287.130 230 294 3.2E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS05140 d5b387ffbd06e2705d5958c73f22e8f8 469 SMART SM00387 350 463 2.3E-27 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS05140 d5b387ffbd06e2705d5958c73f22e8f8 469 SUPERFAMILY SSF55874 296 462 2.1E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS05140 d5b387ffbd06e2705d5958c73f22e8f8 469 Pfam PF00672 HAMP domain 168 235 4.3E-12 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS05140 d5b387ffbd06e2705d5958c73f22e8f8 469 SMART SM00304 186 239 1.4E-9 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS05140 d5b387ffbd06e2705d5958c73f22e8f8 469 SMART SM00388 240 306 4.5E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS05140 d5b387ffbd06e2705d5958c73f22e8f8 469 SUPERFAMILY SSF47384 223 306 4.32E-16 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS01420 a8432bf0c39b2f3989ea10ca987075d2 730 Gene3D G3DSA:3.40.50.720 245 375 3.6E-29 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS01420 a8432bf0c39b2f3989ea10ca987075d2 730 Gene3D G3DSA:3.30.470.20 100 229 1.1E-5 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS01420 a8432bf0c39b2f3989ea10ca987075d2 730 Gene3D G3DSA:3.40.50.261 376 529 3.5E-30 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS01420 a8432bf0c39b2f3989ea10ca987075d2 730 SUPERFAMILY SSF51735 248 375 2.63E-29 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS01420 a8432bf0c39b2f3989ea10ca987075d2 730 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 396 533 1.2E-43 T 22-04-2016 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain HRM2_RS01420 a8432bf0c39b2f3989ea10ca987075d2 730 Pfam PF13380 CoA binding domain 255 379 6.3E-18 T 22-04-2016 IPR003781 CoA-binding GO:0048037 HRM2_RS01420 a8432bf0c39b2f3989ea10ca987075d2 730 Gene3D G3DSA:3.30.470.20 26 67 2.3E-5 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS01420 a8432bf0c39b2f3989ea10ca987075d2 730 SMART SM00881 250 345 5.0E-19 T 22-04-2016 IPR003781 CoA-binding GO:0048037 HRM2_RS01420 a8432bf0c39b2f3989ea10ca987075d2 730 SUPERFAMILY SSF56059 21 234 4.99E-41 T 22-04-2016 HRM2_RS01420 a8432bf0c39b2f3989ea10ca987075d2 730 PANTHER PTHR11117:SF8 229 621 4.5E-106 T 22-04-2016 HRM2_RS01420 a8432bf0c39b2f3989ea10ca987075d2 730 SUPERFAMILY SSF52210 376 533 1.57E-34 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS01420 a8432bf0c39b2f3989ea10ca987075d2 730 Pfam PF13549 ATP-grasp domain 14 229 2.6E-59 T 22-04-2016 HRM2_RS01420 a8432bf0c39b2f3989ea10ca987075d2 730 Gene3D G3DSA:3.40.50.261 537 639 1.7E-4 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS01420 a8432bf0c39b2f3989ea10ca987075d2 730 PANTHER PTHR11117 229 621 4.5E-106 T 22-04-2016 HRM2_RS01420 a8432bf0c39b2f3989ea10ca987075d2 730 SUPERFAMILY SSF52210 539 632 2.09E-23 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS01420 a8432bf0c39b2f3989ea10ca987075d2 730 SUPERFAMILY SSF52210 661 727 2.09E-23 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS25440 d8d0eb6706675a49b7cae0c55f4cfa89 772 SUPERFAMILY SSF47384 350 436 7.26E-24 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25440 d8d0eb6706675a49b7cae0c55f4cfa89 772 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 483 617 1.0E-23 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25440 d8d0eb6706675a49b7cae0c55f4cfa89 772 Pfam PF00989 PAS fold 236 342 1.7E-16 T 22-04-2016 IPR013767 PAS fold GO:0006355 HRM2_RS25440 d8d0eb6706675a49b7cae0c55f4cfa89 772 Gene3D G3DSA:3.30.450.20 244 345 3.1E-27 T 22-04-2016 HRM2_RS25440 d8d0eb6706675a49b7cae0c55f4cfa89 772 SUPERFAMILY SSF102405 1 177 3.21E-53 T 22-04-2016 HRM2_RS25440 d8d0eb6706675a49b7cae0c55f4cfa89 772 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 2 174 4.8E-48 T 22-04-2016 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG HRM2_RS25440 d8d0eb6706675a49b7cae0c55f4cfa89 772 SMART SM00387 482 619 1.1E-35 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25440 d8d0eb6706675a49b7cae0c55f4cfa89 772 Gene3D G3DSA:1.10.287.130 360 419 9.0E-18 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25440 d8d0eb6706675a49b7cae0c55f4cfa89 772 PRINTS PR00344 Bacterial sensor protein C-terminal signature 561 571 1.1E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25440 d8d0eb6706675a49b7cae0c55f4cfa89 772 PRINTS PR00344 Bacterial sensor protein C-terminal signature 578 596 1.1E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25440 d8d0eb6706675a49b7cae0c55f4cfa89 772 PRINTS PR00344 Bacterial sensor protein C-terminal signature 603 616 1.1E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25440 d8d0eb6706675a49b7cae0c55f4cfa89 772 PRINTS PR00344 Bacterial sensor protein C-terminal signature 543 557 1.1E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25440 d8d0eb6706675a49b7cae0c55f4cfa89 772 SUPERFAMILY SSF55785 241 343 7.15E-29 T 22-04-2016 IPR000014 PAS domain HRM2_RS25440 d8d0eb6706675a49b7cae0c55f4cfa89 772 SUPERFAMILY SSF55874 423 619 2.13E-40 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25440 d8d0eb6706675a49b7cae0c55f4cfa89 772 PANTHER PTHR24423:SF491 229 523 8.5E-105 T 22-04-2016 HRM2_RS25440 d8d0eb6706675a49b7cae0c55f4cfa89 772 PANTHER PTHR24423:SF491 543 617 8.5E-105 T 22-04-2016 HRM2_RS25440 d8d0eb6706675a49b7cae0c55f4cfa89 772 SMART SM00388 366 434 9.7E-27 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25440 d8d0eb6706675a49b7cae0c55f4cfa89 772 SMART SM00091 232 298 1.5E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS25440 d8d0eb6706675a49b7cae0c55f4cfa89 772 Pfam PF00512 His Kinase A (phospho-acceptor) domain 366 434 2.6E-21 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25440 d8d0eb6706675a49b7cae0c55f4cfa89 772 SMART SM00086 304 346 3.4E-7 T 22-04-2016 IPR001610 PAC motif HRM2_RS25440 d8d0eb6706675a49b7cae0c55f4cfa89 772 Pfam PF03641 Possible lysine decarboxylase 46 174 6.3E-34 T 22-04-2016 IPR031100 LOG family HRM2_RS25440 d8d0eb6706675a49b7cae0c55f4cfa89 772 Gene3D G3DSA:3.30.565.10 420 617 9.8E-42 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25440 d8d0eb6706675a49b7cae0c55f4cfa89 772 Gene3D G3DSA:3.40.50.450 2 177 3.3E-57 T 22-04-2016 HRM2_RS25440 d8d0eb6706675a49b7cae0c55f4cfa89 772 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 234 353 4.3E-21 T 22-04-2016 IPR000014 PAS domain HRM2_RS25440 d8d0eb6706675a49b7cae0c55f4cfa89 772 PANTHER PTHR24423 229 523 8.5E-105 T 22-04-2016 HRM2_RS25440 d8d0eb6706675a49b7cae0c55f4cfa89 772 PANTHER PTHR24423 543 617 8.5E-105 T 22-04-2016 HRM2_RS14445 d742afd4d6ce2b640b8991e67c644786 549 PANTHER PTHR30029 1 182 2.8E-133 T 22-04-2016 HRM2_RS14445 d742afd4d6ce2b640b8991e67c644786 549 PANTHER PTHR30029 203 517 2.8E-133 T 22-04-2016 HRM2_RS14445 d742afd4d6ce2b640b8991e67c644786 549 Pfam PF04293 SpoVR like protein 7 445 1.2E-61 T 22-04-2016 IPR007390 Sporulation stage V, protein R HRM2_RS14445 d742afd4d6ce2b640b8991e67c644786 549 PANTHER PTHR30029:SF2 1 182 2.8E-133 T 22-04-2016 HRM2_RS14445 d742afd4d6ce2b640b8991e67c644786 549 PANTHER PTHR30029:SF2 203 517 2.8E-133 T 22-04-2016 HRM2_RS23110 9494b1de46e792482ad9b83d8e126094 393 PANTHER PTHR10617 329 393 7.5E-118 T 22-04-2016 HRM2_RS23110 9494b1de46e792482ad9b83d8e126094 393 PANTHER PTHR10617 1 286 7.5E-118 T 22-04-2016 HRM2_RS23110 9494b1de46e792482ad9b83d8e126094 393 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 3.3E-6 T 22-04-2016 HRM2_RS23110 9494b1de46e792482ad9b83d8e126094 393 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.3E-6 T 22-04-2016 HRM2_RS23110 9494b1de46e792482ad9b83d8e126094 393 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 346 368 3.3E-6 T 22-04-2016 HRM2_RS23110 9494b1de46e792482ad9b83d8e126094 393 Pfam PF03486 HI0933-like protein 5 391 7.8E-148 T 22-04-2016 HRM2_RS23110 9494b1de46e792482ad9b83d8e126094 393 PANTHER PTHR10617:SF103 329 393 7.5E-118 T 22-04-2016 HRM2_RS23110 9494b1de46e792482ad9b83d8e126094 393 PANTHER PTHR10617:SF103 1 286 7.5E-118 T 22-04-2016 HRM2_RS23110 9494b1de46e792482ad9b83d8e126094 393 Gene3D G3DSA:2.40.30.10 189 269 3.8E-26 T 22-04-2016 HRM2_RS23110 9494b1de46e792482ad9b83d8e126094 393 SUPERFAMILY SSF51905 3 189 6.18E-58 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS23110 9494b1de46e792482ad9b83d8e126094 393 SUPERFAMILY SSF51905 336 392 6.18E-58 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS23110 9494b1de46e792482ad9b83d8e126094 393 SUPERFAMILY SSF160996 190 339 1.31E-38 T 22-04-2016 HRM2_RS23110 9494b1de46e792482ad9b83d8e126094 393 Gene3D G3DSA:3.50.50.60 338 392 3.7E-53 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS23110 9494b1de46e792482ad9b83d8e126094 393 Gene3D G3DSA:3.50.50.60 3 187 3.7E-53 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS23110 9494b1de46e792482ad9b83d8e126094 393 Gene3D G3DSA:1.10.8.260 270 320 2.5E-12 T 22-04-2016 IPR023166 HI0933 insert-like domain HRM2_RS23110 9494b1de46e792482ad9b83d8e126094 393 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 165 3.6E-9 T 22-04-2016 HRM2_RS23110 9494b1de46e792482ad9b83d8e126094 393 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 3.6E-9 T 22-04-2016 HRM2_RS23110 9494b1de46e792482ad9b83d8e126094 393 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 361 368 3.6E-9 T 22-04-2016 HRM2_RS23110 9494b1de46e792482ad9b83d8e126094 393 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 6 391 2.7E-127 T 22-04-2016 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like HRM2_RS21240 2b4767aacb6bab6929134668fd6890ea 443 Pfam PF02667 Short chain fatty acid transporter 2 443 2.7E-168 T 22-04-2016 IPR006160 Short chain fatty acid transporter AtoE HRM2_RS21240 2b4767aacb6bab6929134668fd6890ea 443 PANTHER PTHR41983:SF2 11 443 5.2E-217 T 22-04-2016 HRM2_RS21240 2b4767aacb6bab6929134668fd6890ea 443 PANTHER PTHR41983 11 443 5.2E-217 T 22-04-2016 HRM2_RS07130 b594ee52701826f4ea53fde4b0e22118 599 Gene3D G3DSA:3.60.9.10 8 213 9.4E-72 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS07130 b594ee52701826f4ea53fde4b0e22118 599 PANTHER PTHR30038:SF0 4 592 2.8E-178 T 22-04-2016 HRM2_RS07130 b594ee52701826f4ea53fde4b0e22118 599 Gene3D G3DSA:1.10.569.10 244 436 5.3E-54 T 22-04-2016 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 HRM2_RS07130 b594ee52701826f4ea53fde4b0e22118 599 PANTHER PTHR30038 4 592 2.8E-178 T 22-04-2016 HRM2_RS07130 b594ee52701826f4ea53fde4b0e22118 599 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 10 209 7.3E-69 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS07130 b594ee52701826f4ea53fde4b0e22118 599 SMART SM00790 10 210 3.3E-76 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS07130 b594ee52701826f4ea53fde4b0e22118 599 SUPERFAMILY SSF56228 7 212 3.79E-61 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS07130 b594ee52701826f4ea53fde4b0e22118 599 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 226 587 4.6E-104 T 22-04-2016 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS07130 b594ee52701826f4ea53fde4b0e22118 599 Gene3D G3DSA:1.10.599.10 466 589 1.8E-41 T 22-04-2016 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 HRM2_RS07130 b594ee52701826f4ea53fde4b0e22118 599 SUPERFAMILY SSF48310 216 596 2.88E-96 T 22-04-2016 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS17145 7ef314cb1ac76ec186dc8602d4baca93 418 Pfam PF02371 Transposase IS116/IS110/IS902 family 263 348 3.9E-16 T 22-04-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 HRM2_RS17145 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055 16 168 8.7E-41 T 22-04-2016 HRM2_RS17145 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055 217 398 8.7E-41 T 22-04-2016 HRM2_RS17145 7ef314cb1ac76ec186dc8602d4baca93 418 Pfam PF01548 Transposase 18 161 3.1E-21 T 22-04-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 HRM2_RS17145 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055:SF3 16 168 8.7E-41 T 22-04-2016 HRM2_RS17145 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055:SF3 217 398 8.7E-41 T 22-04-2016 HRM2_RS11315 7ef314cb1ac76ec186dc8602d4baca93 418 Pfam PF02371 Transposase IS116/IS110/IS902 family 263 348 3.9E-16 T 22-04-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 HRM2_RS11315 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055 16 168 8.7E-41 T 22-04-2016 HRM2_RS11315 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055 217 398 8.7E-41 T 22-04-2016 HRM2_RS11315 7ef314cb1ac76ec186dc8602d4baca93 418 Pfam PF01548 Transposase 18 161 3.1E-21 T 22-04-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 HRM2_RS11315 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055:SF3 16 168 8.7E-41 T 22-04-2016 HRM2_RS11315 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055:SF3 217 398 8.7E-41 T 22-04-2016 HRM2_RS10565 7ef314cb1ac76ec186dc8602d4baca93 418 Pfam PF02371 Transposase IS116/IS110/IS902 family 263 348 3.9E-16 T 22-04-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 HRM2_RS10565 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055 16 168 8.7E-41 T 22-04-2016 HRM2_RS10565 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055 217 398 8.7E-41 T 22-04-2016 HRM2_RS10565 7ef314cb1ac76ec186dc8602d4baca93 418 Pfam PF01548 Transposase 18 161 3.1E-21 T 22-04-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 HRM2_RS10565 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055:SF3 16 168 8.7E-41 T 22-04-2016 HRM2_RS10565 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055:SF3 217 398 8.7E-41 T 22-04-2016 HRM2_RS21580 7ef314cb1ac76ec186dc8602d4baca93 418 Pfam PF02371 Transposase IS116/IS110/IS902 family 263 348 3.9E-16 T 22-04-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 HRM2_RS21580 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055 16 168 8.7E-41 T 22-04-2016 HRM2_RS21580 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055 217 398 8.7E-41 T 22-04-2016 HRM2_RS21580 7ef314cb1ac76ec186dc8602d4baca93 418 Pfam PF01548 Transposase 18 161 3.1E-21 T 22-04-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 HRM2_RS21580 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055:SF3 16 168 8.7E-41 T 22-04-2016 HRM2_RS21580 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055:SF3 217 398 8.7E-41 T 22-04-2016 HRM2_RS07735 7ef314cb1ac76ec186dc8602d4baca93 418 Pfam PF02371 Transposase IS116/IS110/IS902 family 263 348 3.9E-16 T 22-04-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 HRM2_RS07735 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055 16 168 8.7E-41 T 22-04-2016 HRM2_RS07735 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055 217 398 8.7E-41 T 22-04-2016 HRM2_RS07735 7ef314cb1ac76ec186dc8602d4baca93 418 Pfam PF01548 Transposase 18 161 3.1E-21 T 22-04-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 HRM2_RS07735 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055:SF3 16 168 8.7E-41 T 22-04-2016 HRM2_RS07735 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055:SF3 217 398 8.7E-41 T 22-04-2016 HRM2_RS23025 7ef314cb1ac76ec186dc8602d4baca93 418 Pfam PF02371 Transposase IS116/IS110/IS902 family 263 348 3.9E-16 T 22-04-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 HRM2_RS23025 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055 16 168 8.7E-41 T 22-04-2016 HRM2_RS23025 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055 217 398 8.7E-41 T 22-04-2016 HRM2_RS23025 7ef314cb1ac76ec186dc8602d4baca93 418 Pfam PF01548 Transposase 18 161 3.1E-21 T 22-04-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 HRM2_RS23025 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055:SF3 16 168 8.7E-41 T 22-04-2016 HRM2_RS23025 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055:SF3 217 398 8.7E-41 T 22-04-2016 HRM2_RS14080 7ef314cb1ac76ec186dc8602d4baca93 418 Pfam PF02371 Transposase IS116/IS110/IS902 family 263 348 3.9E-16 T 22-04-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 HRM2_RS14080 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055 16 168 8.7E-41 T 22-04-2016 HRM2_RS14080 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055 217 398 8.7E-41 T 22-04-2016 HRM2_RS14080 7ef314cb1ac76ec186dc8602d4baca93 418 Pfam PF01548 Transposase 18 161 3.1E-21 T 22-04-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 HRM2_RS14080 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055:SF3 16 168 8.7E-41 T 22-04-2016 HRM2_RS14080 7ef314cb1ac76ec186dc8602d4baca93 418 PANTHER PTHR33055:SF3 217 398 8.7E-41 T 22-04-2016 HRM2_RS16615 53744db136e0c0495d91f7a67b3bf5ba 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 3.3E-11 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS16615 53744db136e0c0495d91f7a67b3bf5ba 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 3.3E-11 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS16615 53744db136e0c0495d91f7a67b3bf5ba 197 PANTHER PTHR30055 11 192 1.1E-24 T 22-04-2016 HRM2_RS16615 53744db136e0c0495d91f7a67b3bf5ba 197 Gene3D G3DSA:1.10.357.10 14 194 7.9E-40 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HRM2_RS16615 53744db136e0c0495d91f7a67b3bf5ba 197 PANTHER PTHR30055:SF76 11 192 1.1E-24 T 22-04-2016 HRM2_RS16615 53744db136e0c0495d91f7a67b3bf5ba 197 SUPERFAMILY SSF46689 5 68 7.98E-18 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS16615 53744db136e0c0495d91f7a67b3bf5ba 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 1.5E-17 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS19765 dd1843cef955bcbe2c2193ffba73e48b 1015 SUPERFAMILY SSF82693 271 325 2.62E-14 T 22-04-2016 HRM2_RS19765 dd1843cef955bcbe2c2193ffba73e48b 1015 SUPERFAMILY SSF82693 139 185 2.62E-14 T 22-04-2016 HRM2_RS19765 dd1843cef955bcbe2c2193ffba73e48b 1015 PANTHER PTHR32063 4 1015 0.0 T 22-04-2016 HRM2_RS19765 dd1843cef955bcbe2c2193ffba73e48b 1015 Gene3D G3DSA:3.30.70.1430 559 644 1.2E-5 T 22-04-2016 HRM2_RS19765 dd1843cef955bcbe2c2193ffba73e48b 1015 SUPERFAMILY SSF82714 708 791 2.35E-14 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS19765 dd1843cef955bcbe2c2193ffba73e48b 1015 SUPERFAMILY SSF82866 791 1013 1.44E-39 T 22-04-2016 HRM2_RS19765 dd1843cef955bcbe2c2193ffba73e48b 1015 PANTHER PTHR32063:SF18 4 1015 0.0 T 22-04-2016 HRM2_RS19765 dd1843cef955bcbe2c2193ffba73e48b 1015 Gene3D G3DSA:3.30.2090.10 707 789 3.8E-15 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS19765 dd1843cef955bcbe2c2193ffba73e48b 1015 Gene3D G3DSA:3.30.2090.10 188 267 6.8E-6 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS19765 dd1843cef955bcbe2c2193ffba73e48b 1015 PRINTS PR00702 Acriflavin resistance protein family signature 465 488 4.9E-22 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS19765 dd1843cef955bcbe2c2193ffba73e48b 1015 PRINTS PR00702 Acriflavin resistance protein family signature 41 59 4.9E-22 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS19765 dd1843cef955bcbe2c2193ffba73e48b 1015 PRINTS PR00702 Acriflavin resistance protein family signature 387 411 4.9E-22 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS19765 dd1843cef955bcbe2c2193ffba73e48b 1015 PRINTS PR00702 Acriflavin resistance protein family signature 440 463 4.9E-22 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS19765 dd1843cef955bcbe2c2193ffba73e48b 1015 PRINTS PR00702 Acriflavin resistance protein family signature 333 356 4.9E-22 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS19765 dd1843cef955bcbe2c2193ffba73e48b 1015 SUPERFAMILY SSF82693 558 649 2.09E-6 T 22-04-2016 HRM2_RS19765 dd1843cef955bcbe2c2193ffba73e48b 1015 SUPERFAMILY SSF82693 43 137 8.89E-18 T 22-04-2016 HRM2_RS19765 dd1843cef955bcbe2c2193ffba73e48b 1015 Gene3D G3DSA:1.10.3850.10 798 1011 6.9E-48 T 22-04-2016 HRM2_RS19765 dd1843cef955bcbe2c2193ffba73e48b 1015 Gene3D G3DSA:1.10.3850.10 278 494 1.9E-45 T 22-04-2016 HRM2_RS19765 dd1843cef955bcbe2c2193ffba73e48b 1015 Pfam PF00873 AcrB/AcrD/AcrF family 8 1007 2.2E-156 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS19765 dd1843cef955bcbe2c2193ffba73e48b 1015 SUPERFAMILY SSF82714 188 266 2.09E-7 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS19765 dd1843cef955bcbe2c2193ffba73e48b 1015 Gene3D G3DSA:3.30.70.1430 43 141 9.5E-20 T 22-04-2016 HRM2_RS19765 dd1843cef955bcbe2c2193ffba73e48b 1015 SUPERFAMILY SSF82866 300 492 4.05E-37 T 22-04-2016 HRM2_RS18510 efe1a6956f2def5f37676c23db7497f2 204 PANTHER PTHR40593 46 204 9.6E-23 T 22-04-2016 HRM2_RS18510 efe1a6956f2def5f37676c23db7497f2 204 Pfam PF13036 Peptidoglycan-synthase activator LpoB 14 192 2.2E-37 T 22-04-2016 IPR014094 Penicillin-binding protein activator LpoB HRM2_RS18510 efe1a6956f2def5f37676c23db7497f2 204 TIGRFAM TIGR02722 lp_: uncharacterized lipoprotein 10 192 1.3E-32 T 22-04-2016 IPR014094 Penicillin-binding protein activator LpoB HRM2_RS23400 6f3174c12fc368d096a60da47df35359 806 Pfam PF00672 HAMP domain 344 401 3.8E-7 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS23400 6f3174c12fc368d096a60da47df35359 806 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 665 787 3.3E-18 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS23400 6f3174c12fc368d096a60da47df35359 806 PRINTS PR00344 Bacterial sensor protein C-terminal signature 749 767 9.7E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS23400 6f3174c12fc368d096a60da47df35359 806 PRINTS PR00344 Bacterial sensor protein C-terminal signature 734 744 9.7E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS23400 6f3174c12fc368d096a60da47df35359 806 PRINTS PR00344 Bacterial sensor protein C-terminal signature 773 786 9.7E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS23400 6f3174c12fc368d096a60da47df35359 806 PRINTS PR00344 Bacterial sensor protein C-terminal signature 716 730 9.7E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS23400 6f3174c12fc368d096a60da47df35359 806 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 424 551 2.3E-15 T 22-04-2016 IPR000014 PAS domain HRM2_RS23400 6f3174c12fc368d096a60da47df35359 806 SMART SM00388 559 625 2.1E-4 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS23400 6f3174c12fc368d096a60da47df35359 806 SUPERFAMILY SSF55874 624 788 3.41E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS23400 6f3174c12fc368d096a60da47df35359 806 PANTHER PTHR24423 20 28 3.2E-65 T 22-04-2016 HRM2_RS23400 6f3174c12fc368d096a60da47df35359 806 PANTHER PTHR24423 411 786 3.2E-65 T 22-04-2016 HRM2_RS23400 6f3174c12fc368d096a60da47df35359 806 SUPERFAMILY SSF158472 358 403 7.32E-8 T 22-04-2016 HRM2_RS23400 6f3174c12fc368d096a60da47df35359 806 SUPERFAMILY SSF47384 555 622 2.16E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS23400 6f3174c12fc368d096a60da47df35359 806 SMART SM00304 357 410 2.2E-6 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS23400 6f3174c12fc368d096a60da47df35359 806 Pfam PF08447 PAS fold 450 530 1.2E-8 T 22-04-2016 IPR013655 PAS fold-3 GO:0005515 HRM2_RS23400 6f3174c12fc368d096a60da47df35359 806 Gene3D G3DSA:3.30.565.10 601 788 4.9E-30 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS23400 6f3174c12fc368d096a60da47df35359 806 Gene3D G3DSA:3.30.450.20 418 542 6.9E-17 T 22-04-2016 HRM2_RS23400 6f3174c12fc368d096a60da47df35359 806 SMART SM00387 664 789 2.1E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS23400 6f3174c12fc368d096a60da47df35359 806 SUPERFAMILY SSF55785 414 542 2.42E-17 T 22-04-2016 IPR000014 PAS domain HRM2_RS12350 a1198ea32405c4f5413ff00024666caa 252 PRINTS PR00625 DnaJ domain signature 207 222 4.6E-11 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS12350 a1198ea32405c4f5413ff00024666caa 252 PRINTS PR00625 DnaJ domain signature 231 251 4.6E-11 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS12350 a1198ea32405c4f5413ff00024666caa 252 PRINTS PR00625 DnaJ domain signature 189 207 4.6E-11 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS12350 a1198ea32405c4f5413ff00024666caa 252 SUPERFAMILY SSF158682 20 201 1.75E-27 T 22-04-2016 IPR029024 TerB-like HRM2_RS12350 a1198ea32405c4f5413ff00024666caa 252 Gene3D G3DSA:1.10.3680.10 20 191 1.0E-28 T 22-04-2016 IPR029024 TerB-like HRM2_RS12350 a1198ea32405c4f5413ff00024666caa 252 PANTHER PTHR24078 3 41 4.5E-12 T 22-04-2016 HRM2_RS12350 a1198ea32405c4f5413ff00024666caa 252 PANTHER PTHR24078 177 247 4.5E-12 T 22-04-2016 HRM2_RS12350 a1198ea32405c4f5413ff00024666caa 252 Gene3D G3DSA:1.10.287.110 192 248 8.1E-16 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS12350 a1198ea32405c4f5413ff00024666caa 252 SUPERFAMILY SSF46565 183 248 5.53E-16 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS12350 a1198ea32405c4f5413ff00024666caa 252 SMART SM00271 186 251 1.4E-12 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS12350 a1198ea32405c4f5413ff00024666caa 252 Pfam PF05099 Tellurite resistance protein TerB 42 178 1.3E-24 T 22-04-2016 IPR007791 Co-chaperone DjlA, N-terminal HRM2_RS12350 a1198ea32405c4f5413ff00024666caa 252 PANTHER PTHR24078:SF257 3 41 4.5E-12 T 22-04-2016 HRM2_RS12350 a1198ea32405c4f5413ff00024666caa 252 PANTHER PTHR24078:SF257 177 247 4.5E-12 T 22-04-2016 HRM2_RS12350 a1198ea32405c4f5413ff00024666caa 252 Pfam PF00226 DnaJ domain 188 248 2.7E-14 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS23345 1cc6d4d60e22b1431eaa4473ff3cb5ac 897 Pfam PF13302 Acetyltransferase (GNAT) domain 741 880 1.4E-6 T 22-04-2016 IPR000182 GNAT domain GO:0008080 HRM2_RS23345 1cc6d4d60e22b1431eaa4473ff3cb5ac 897 PANTHER PTHR11117 34 714 3.4E-252 T 22-04-2016 HRM2_RS23345 1cc6d4d60e22b1431eaa4473ff3cb5ac 897 SMART SM00881 9 104 3.6E-27 T 22-04-2016 IPR003781 CoA-binding GO:0048037 HRM2_RS23345 1cc6d4d60e22b1431eaa4473ff3cb5ac 897 Gene3D G3DSA:3.30.470.20 586 709 3.1E-5 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS23345 1cc6d4d60e22b1431eaa4473ff3cb5ac 897 Gene3D G3DSA:3.40.630.30 735 888 2.5E-18 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS23345 1cc6d4d60e22b1431eaa4473ff3cb5ac 897 SUPERFAMILY SSF55729 738 887 1.48E-19 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS23345 1cc6d4d60e22b1431eaa4473ff3cb5ac 897 SUPERFAMILY SSF52210 136 294 7.2E-38 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS23345 1cc6d4d60e22b1431eaa4473ff3cb5ac 897 SUPERFAMILY SSF51735 2 144 3.11E-29 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS23345 1cc6d4d60e22b1431eaa4473ff3cb5ac 897 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 157 293 3.7E-49 T 22-04-2016 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain HRM2_RS23345 1cc6d4d60e22b1431eaa4473ff3cb5ac 897 Gene3D G3DSA:3.40.50.261 138 292 2.2E-25 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS23345 1cc6d4d60e22b1431eaa4473ff3cb5ac 897 Gene3D G3DSA:3.40.50.261 295 453 4.4E-17 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS23345 1cc6d4d60e22b1431eaa4473ff3cb5ac 897 SUPERFAMILY SSF52210 301 460 6.02E-35 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS23345 1cc6d4d60e22b1431eaa4473ff3cb5ac 897 Gene3D G3DSA:3.40.50.720 3 137 7.2E-31 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS23345 1cc6d4d60e22b1431eaa4473ff3cb5ac 897 PANTHER PTHR11117:SF8 34 714 3.4E-252 T 22-04-2016 HRM2_RS23345 1cc6d4d60e22b1431eaa4473ff3cb5ac 897 Pfam PF13549 ATP-grasp domain 488 709 3.3E-82 T 22-04-2016 HRM2_RS23345 1cc6d4d60e22b1431eaa4473ff3cb5ac 897 Pfam PF13380 CoA binding domain 14 140 7.1E-18 T 22-04-2016 IPR003781 CoA-binding GO:0048037 HRM2_RS23345 1cc6d4d60e22b1431eaa4473ff3cb5ac 897 SUPERFAMILY SSF56059 500 709 5.3E-34 T 22-04-2016 HRM2_RS17720 1c82c15cf3a4c989a7c9c67319090412 408 PANTHER PTHR21499 1 407 2.1E-166 T 22-04-2016 HRM2_RS17720 1c82c15cf3a4c989a7c9c67319090412 408 Pfam PF00696 Amino acid kinase family 4 230 1.4E-51 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HRM2_RS17720 1c82c15cf3a4c989a7c9c67319090412 408 SUPERFAMILY SSF55021 247 321 2.8E-15 T 22-04-2016 HRM2_RS17720 1c82c15cf3a4c989a7c9c67319090412 408 SUPERFAMILY SSF53633 4 243 4.06E-77 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HRM2_RS17720 1c82c15cf3a4c989a7c9c67319090412 408 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 22-04-2016 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 HRM2_RS17720 1c82c15cf3a4c989a7c9c67319090412 408 Pfam PF01842 ACT domain 268 322 1.9E-7 T 22-04-2016 IPR002912 ACT domain GO:0008152|GO:0016597 HRM2_RS17720 1c82c15cf3a4c989a7c9c67319090412 408 PANTHER PTHR21499:SF27 1 407 2.1E-166 T 22-04-2016 HRM2_RS17720 1c82c15cf3a4c989a7c9c67319090412 408 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 2 401 1.1E-133 T 22-04-2016 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 HRM2_RS17720 1c82c15cf3a4c989a7c9c67319090412 408 Gene3D G3DSA:3.40.1160.10 1 247 8.9E-74 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HRM2_RS17720 1c82c15cf3a4c989a7c9c67319090412 408 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 60 401 3.2E-118 T 22-04-2016 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 HRM2_RS17720 1c82c15cf3a4c989a7c9c67319090412 408 SUPERFAMILY SSF55021 328 404 3.97E-24 T 22-04-2016 HRM2_RS17720 1c82c15cf3a4c989a7c9c67319090412 408 Pfam PF13840 ACT domain 336 397 1.8E-14 T 22-04-2016 IPR027795 GATS-like ACT domain HRM2_RS17720 1c82c15cf3a4c989a7c9c67319090412 408 PIRSF PIRSF000726 59 408 1.1E-131 T 22-04-2016 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 HRM2_RS04400 b548f862b54727da94987dfc97cc7042 969 Gene3D G3DSA:1.20.1580.10 113 151 3.7E-52 T 22-04-2016 HRM2_RS04400 b548f862b54727da94987dfc97cc7042 969 Gene3D G3DSA:1.20.1580.10 434 504 3.7E-52 T 22-04-2016 HRM2_RS04400 b548f862b54727da94987dfc97cc7042 969 Gene3D G3DSA:1.20.1580.10 271 303 3.7E-52 T 22-04-2016 HRM2_RS04400 b548f862b54727da94987dfc97cc7042 969 Gene3D G3DSA:3.30.1490.20 222 270 5.8E-21 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HRM2_RS04400 b548f862b54727da94987dfc97cc7042 969 Gene3D G3DSA:3.30.1490.20 155 175 5.8E-21 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HRM2_RS04400 b548f862b54727da94987dfc97cc7042 969 Gene3D G3DSA:1.10.8.280 307 433 1.4E-28 T 22-04-2016 HRM2_RS04400 b548f862b54727da94987dfc97cc7042 969 SUPERFAMILY SSF52540 457 596 1.55E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04400 b548f862b54727da94987dfc97cc7042 969 SUPERFAMILY SSF52540 30 226 1.55E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04400 b548f862b54727da94987dfc97cc7042 969 Pfam PF00005 ABC transporter 652 888 1.0E-12 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS04400 b548f862b54727da94987dfc97cc7042 969 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 26 953 0.0 T 22-04-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 HRM2_RS04400 b548f862b54727da94987dfc97cc7042 969 SMART SM00382 661 934 5.9E-4 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS04400 b548f862b54727da94987dfc97cc7042 969 SUPERFAMILY SSF52540 642 941 1.47E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04400 b548f862b54727da94987dfc97cc7042 969 Gene3D G3DSA:1.20.1580.10 722 848 2.4E-51 T 22-04-2016 HRM2_RS04400 b548f862b54727da94987dfc97cc7042 969 Gene3D G3DSA:3.40.50.300 849 967 5.9E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04400 b548f862b54727da94987dfc97cc7042 969 Gene3D G3DSA:3.40.50.300 629 720 5.9E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04400 b548f862b54727da94987dfc97cc7042 969 Gene3D G3DSA:3.40.50.300 505 622 6.8E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04400 b548f862b54727da94987dfc97cc7042 969 Gene3D G3DSA:3.40.50.300 20 73 6.8E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04400 b548f862b54727da94987dfc97cc7042 969 Hamap MF_00205 UvrABC system protein A [uvrA]. 23 968 21.463 T 22-04-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 HRM2_RS04400 b548f862b54727da94987dfc97cc7042 969 PANTHER PTHR32282:SF2 22 968 0.0 T 22-04-2016 HRM2_RS04400 b548f862b54727da94987dfc97cc7042 969 ProSitePatterns PS00211 ABC transporters family signature. 858 872 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS04400 b548f862b54727da94987dfc97cc7042 969 ProSitePatterns PS00211 ABC transporters family signature. 514 528 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS04400 b548f862b54727da94987dfc97cc7042 969 PANTHER PTHR32282 22 968 0.0 T 22-04-2016 HRM2_RS18195 dc2fb4c51ff883d26ce4a5984c9dc26f 792 Pfam PF00700 Bacterial flagellin C-terminal helical region 707 791 5.9E-23 T 22-04-2016 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 HRM2_RS18195 dc2fb4c51ff883d26ce4a5984c9dc26f 792 SUPERFAMILY SSF51161 365 529 6.73E-9 T 22-04-2016 IPR011004 Trimeric LpxA-like HRM2_RS18195 dc2fb4c51ff883d26ce4a5984c9dc26f 792 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 143 8.4E-38 T 22-04-2016 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 HRM2_RS18195 dc2fb4c51ff883d26ce4a5984c9dc26f 792 PANTHER PTHR30244 626 792 9.2E-86 T 22-04-2016 HRM2_RS18195 dc2fb4c51ff883d26ce4a5984c9dc26f 792 PANTHER PTHR30244 2 173 9.2E-86 T 22-04-2016 HRM2_RS18195 dc2fb4c51ff883d26ce4a5984c9dc26f 792 PANTHER PTHR30244:SF1 626 792 9.2E-86 T 22-04-2016 HRM2_RS18195 dc2fb4c51ff883d26ce4a5984c9dc26f 792 PANTHER PTHR30244:SF1 2 173 9.2E-86 T 22-04-2016 HRM2_RS18195 dc2fb4c51ff883d26ce4a5984c9dc26f 792 Pfam PF07196 Flagellin hook IN motif 253 303 1.2E-7 T 22-04-2016 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 HRM2_RS18195 dc2fb4c51ff883d26ce4a5984c9dc26f 792 PRINTS PR00207 Flagellin signature 111 134 7.1E-19 T 22-04-2016 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 HRM2_RS18195 dc2fb4c51ff883d26ce4a5984c9dc26f 792 PRINTS PR00207 Flagellin signature 37 54 7.1E-19 T 22-04-2016 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 HRM2_RS18195 dc2fb4c51ff883d26ce4a5984c9dc26f 792 PRINTS PR00207 Flagellin signature 76 95 7.1E-19 T 22-04-2016 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 HRM2_RS18195 dc2fb4c51ff883d26ce4a5984c9dc26f 792 Gene3D G3DSA:1.20.1330.10 55 171 6.7E-25 T 22-04-2016 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 HRM2_RS18195 dc2fb4c51ff883d26ce4a5984c9dc26f 792 Gene3D G3DSA:1.20.1330.10 645 748 8.7E-16 T 22-04-2016 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 HRM2_RS18195 dc2fb4c51ff883d26ce4a5984c9dc26f 792 Gene3D G3DSA:2.160.10.10 493 644 1.7E-5 T 22-04-2016 HRM2_RS18195 dc2fb4c51ff883d26ce4a5984c9dc26f 792 SUPERFAMILY SSF64518 1 310 5.49E-69 T 22-04-2016 HRM2_RS18195 dc2fb4c51ff883d26ce4a5984c9dc26f 792 SUPERFAMILY SSF64518 602 792 5.49E-69 T 22-04-2016 HRM2_RS18195 dc2fb4c51ff883d26ce4a5984c9dc26f 792 Gene3D G3DSA:2.160.10.10 362 478 3.0E-8 T 22-04-2016 HRM2_RS11245 4980ab9918ea0cb97a30be1b3b259509 327 SUPERFAMILY SSF52922 193 326 7.72E-37 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HRM2_RS11245 4980ab9918ea0cb97a30be1b3b259509 327 Gene3D G3DSA:3.40.50.920 196 325 1.7E-41 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HRM2_RS11245 4980ab9918ea0cb97a30be1b3b259509 327 Pfam PF02780 Transketolase, C-terminal domain 195 317 9.9E-39 T 22-04-2016 IPR033248 Transketolase, C-terminal domain HRM2_RS11245 4980ab9918ea0cb97a30be1b3b259509 327 SMART SM00861 4 181 6.7E-48 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain HRM2_RS11245 4980ab9918ea0cb97a30be1b3b259509 327 SUPERFAMILY SSF52518 4 189 1.61E-54 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS11245 4980ab9918ea0cb97a30be1b3b259509 327 PANTHER PTHR11624:SF77 1 327 4.5E-118 T 22-04-2016 HRM2_RS11245 4980ab9918ea0cb97a30be1b3b259509 327 PANTHER PTHR11624 1 327 4.5E-118 T 22-04-2016 IPR033247 Transketolase family HRM2_RS11245 4980ab9918ea0cb97a30be1b3b259509 327 Pfam PF02779 Transketolase, pyrimidine binding domain 5 180 5.0E-35 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain HRM2_RS11245 4980ab9918ea0cb97a30be1b3b259509 327 Gene3D G3DSA:3.40.50.970 2 195 6.1E-68 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS23950 0225dd2b6a0672d81cd70644579b02cf 802 PANTHER PTHR23309:SF2 1 472 1.3E-107 T 22-04-2016 HRM2_RS23950 0225dd2b6a0672d81cd70644579b02cf 802 Pfam PF00378 Enoyl-CoA hydratase/isomerase 489 629 5.6E-15 T 22-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 HRM2_RS23950 0225dd2b6a0672d81cd70644579b02cf 802 Gene3D G3DSA:3.90.226.10 485 697 7.0E-26 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS23950 0225dd2b6a0672d81cd70644579b02cf 802 SUPERFAMILY SSF48179 359 455 8.42E-14 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HRM2_RS23950 0225dd2b6a0672d81cd70644579b02cf 802 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 198 2.2E-44 T 22-04-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 HRM2_RS23950 0225dd2b6a0672d81cd70644579b02cf 802 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 202 301 1.0E-12 T 22-04-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 HRM2_RS23950 0225dd2b6a0672d81cd70644579b02cf 802 SUPERFAMILY SSF51735 4 200 4.06E-44 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS23950 0225dd2b6a0672d81cd70644579b02cf 802 SUPERFAMILY SSF52096 483 799 1.91E-39 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS23950 0225dd2b6a0672d81cd70644579b02cf 802 Gene3D G3DSA:1.10.1040.10 203 301 1.2E-13 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HRM2_RS23950 0225dd2b6a0672d81cd70644579b02cf 802 Gene3D G3DSA:1.10.1040.10 370 438 1.3E-9 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HRM2_RS23950 0225dd2b6a0672d81cd70644579b02cf 802 SUPERFAMILY SSF48179 200 303 1.45E-16 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HRM2_RS23950 0225dd2b6a0672d81cd70644579b02cf 802 PANTHER PTHR23309 1 472 1.3E-107 T 22-04-2016 HRM2_RS23950 0225dd2b6a0672d81cd70644579b02cf 802 Gene3D G3DSA:3.40.50.720 3 202 2.2E-43 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS00580 eb1140e3e61d76e5f1d2130190dd60be 946 Gene3D G3DSA:3.30.465.10 105 186 2.4E-15 T 22-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 HRM2_RS00580 eb1140e3e61d76e5f1d2130190dd60be 946 Gene3D G3DSA:3.30.465.10 218 263 2.4E-15 T 22-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 HRM2_RS00580 eb1140e3e61d76e5f1d2130190dd60be 946 Pfam PF13183 4Fe-4S dicluster domain 540 613 8.0E-9 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS00580 eb1140e3e61d76e5f1d2130190dd60be 946 PANTHER PTHR11748:SF65 222 564 3.2E-261 T 22-04-2016 HRM2_RS00580 eb1140e3e61d76e5f1d2130190dd60be 946 PANTHER PTHR11748:SF65 3 185 3.2E-261 T 22-04-2016 HRM2_RS00580 eb1140e3e61d76e5f1d2130190dd60be 946 Pfam PF01565 FAD binding domain 43 179 7.4E-28 T 22-04-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 HRM2_RS00580 eb1140e3e61d76e5f1d2130190dd60be 946 Gene3D G3DSA:3.30.43.10 4 92 1.5E-14 T 22-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 HRM2_RS00580 eb1140e3e61d76e5f1d2130190dd60be 946 Pfam PF02754 Cysteine-rich domain 710 805 0.0027 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS00580 eb1140e3e61d76e5f1d2130190dd60be 946 Pfam PF02754 Cysteine-rich domain 839 894 0.11 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS00580 eb1140e3e61d76e5f1d2130190dd60be 946 SUPERFAMILY SSF56176 7 264 2.45E-53 T 22-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 HRM2_RS00580 eb1140e3e61d76e5f1d2130190dd60be 946 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 542 553 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS00580 eb1140e3e61d76e5f1d2130190dd60be 946 Gene3D G3DSA:1.10.45.10 478 507 9.1E-9 T 22-04-2016 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 HRM2_RS00580 eb1140e3e61d76e5f1d2130190dd60be 946 SUPERFAMILY SSF55103 271 522 5.4E-54 T 22-04-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 HRM2_RS00580 eb1140e3e61d76e5f1d2130190dd60be 946 SUPERFAMILY SSF46548 503 627 1.74E-20 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS00580 eb1140e3e61d76e5f1d2130190dd60be 946 Gene3D G3DSA:1.10.1060.10 508 630 8.1E-17 T 22-04-2016 HRM2_RS00580 eb1140e3e61d76e5f1d2130190dd60be 946 Pfam PF02913 FAD linked oxidases, C-terminal domain 269 516 2.6E-54 T 22-04-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 HRM2_RS00580 eb1140e3e61d76e5f1d2130190dd60be 946 PANTHER PTHR11748 222 564 3.2E-261 T 22-04-2016 HRM2_RS00580 eb1140e3e61d76e5f1d2130190dd60be 946 PANTHER PTHR11748 3 185 3.2E-261 T 22-04-2016 HRM2_RS16380 58fd16b3eac398dab3cde5e030e93a1a 293 PANTHER PTHR13696 28 292 5.6E-44 T 22-04-2016 HRM2_RS16380 58fd16b3eac398dab3cde5e030e93a1a 293 SUPERFAMILY SSF52540 40 292 2.86E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16380 58fd16b3eac398dab3cde5e030e93a1a 293 Gene3D G3DSA:3.40.50.300 42 290 2.1E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16380 58fd16b3eac398dab3cde5e030e93a1a 293 Pfam PF13614 AAA domain 42 217 6.0E-38 T 22-04-2016 IPR025669 AAA domain HRM2_RS24855 001a6417fc2f1a2eca793bc1bb31cd76 567 SUPERFAMILY SSF46548 308 416 1.23E-14 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS24855 001a6417fc2f1a2eca793bc1bb31cd76 567 PANTHER PTHR11921:SF22 467 547 2.4E-12 T 22-04-2016 HRM2_RS24855 001a6417fc2f1a2eca793bc1bb31cd76 567 Gene3D G3DSA:1.10.1060.10 476 548 5.8E-16 T 22-04-2016 HRM2_RS24855 001a6417fc2f1a2eca793bc1bb31cd76 567 SUPERFAMILY SSF103501 57 131 1.31E-6 T 22-04-2016 IPR023234 NarG-like domain HRM2_RS24855 001a6417fc2f1a2eca793bc1bb31cd76 567 SUPERFAMILY SSF103501 2 30 1.31E-6 T 22-04-2016 IPR023234 NarG-like domain HRM2_RS24855 001a6417fc2f1a2eca793bc1bb31cd76 567 Gene3D G3DSA:1.20.950.20 2 223 9.7E-25 T 22-04-2016 HRM2_RS24855 001a6417fc2f1a2eca793bc1bb31cd76 567 Gene3D G3DSA:1.20.950.20 279 317 9.7E-25 T 22-04-2016 HRM2_RS24855 001a6417fc2f1a2eca793bc1bb31cd76 567 SUPERFAMILY SSF46548 465 546 8.2E-18 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS24855 001a6417fc2f1a2eca793bc1bb31cd76 567 Pfam PF13183 4Fe-4S dicluster domain 470 535 1.6E-9 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS24855 001a6417fc2f1a2eca793bc1bb31cd76 567 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 521 532 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS24855 001a6417fc2f1a2eca793bc1bb31cd76 567 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 473 484 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS24855 001a6417fc2f1a2eca793bc1bb31cd76 567 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 397 408 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS24855 001a6417fc2f1a2eca793bc1bb31cd76 567 Pfam PF13534 4Fe-4S dicluster domain 339 412 1.5E-7 T 22-04-2016 HRM2_RS24855 001a6417fc2f1a2eca793bc1bb31cd76 567 Gene3D G3DSA:1.10.1060.10 326 406 2.9E-14 T 22-04-2016 HRM2_RS24855 001a6417fc2f1a2eca793bc1bb31cd76 567 PANTHER PTHR11921 467 547 2.4E-12 T 22-04-2016 HRM2_RS24855 001a6417fc2f1a2eca793bc1bb31cd76 567 SUPERFAMILY SSF103501 283 317 7.06E-8 T 22-04-2016 IPR023234 NarG-like domain HRM2_RS24855 001a6417fc2f1a2eca793bc1bb31cd76 567 Gene3D G3DSA:3.30.70.20 407 475 1.2E-5 T 22-04-2016 HRM2_RS02560 c6996ff490a3bffb1fba181cd4b418ec 155 PANTHER PTHR30154:SF27 1 153 1.3E-47 T 22-04-2016 HRM2_RS02560 c6996ff490a3bffb1fba181cd4b418ec 155 SMART SM00344 2 113 0.0013 T 22-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 HRM2_RS02560 c6996ff490a3bffb1fba181cd4b418ec 155 SUPERFAMILY SSF46785 2 61 7.38E-6 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS02560 c6996ff490a3bffb1fba181cd4b418ec 155 Gene3D G3DSA:1.10.10.10 2 83 4.3E-9 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS02560 c6996ff490a3bffb1fba181cd4b418ec 155 Gene3D G3DSA:3.30.70.920 84 145 6.3E-4 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain HRM2_RS02560 c6996ff490a3bffb1fba181cd4b418ec 155 PANTHER PTHR30154 1 153 1.3E-47 T 22-04-2016 HRM2_RS08880 6c0f64c1e84a9508938d5935abd6158b 229 ProSitePatterns PS00449 ATP synthase a subunit signature. 166 175 - T 22-04-2016 IPR023011 ATPase, F0 complex, subunit A, active site HRM2_RS08880 6c0f64c1e84a9508938d5935abd6158b 229 PANTHER PTHR11410:SF7 27 229 1.4E-62 T 22-04-2016 HRM2_RS08880 6c0f64c1e84a9508938d5935abd6158b 229 SUPERFAMILY SSF81336 76 221 1.12E-37 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HRM2_RS08880 6c0f64c1e84a9508938d5935abd6158b 229 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 23 222 1.9E-41 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HRM2_RS08880 6c0f64c1e84a9508938d5935abd6158b 229 PRINTS PR00123 ATP synthase A subunit signature 163 185 1.4E-17 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HRM2_RS08880 6c0f64c1e84a9508938d5935abd6158b 229 PRINTS PR00123 ATP synthase A subunit signature 143 158 1.4E-17 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HRM2_RS08880 6c0f64c1e84a9508938d5935abd6158b 229 PRINTS PR00123 ATP synthase A subunit signature 84 100 1.4E-17 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HRM2_RS08880 6c0f64c1e84a9508938d5935abd6158b 229 PRINTS PR00123 ATP synthase A subunit signature 208 223 1.4E-17 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HRM2_RS08880 6c0f64c1e84a9508938d5935abd6158b 229 Pfam PF00119 ATP synthase A chain 27 221 3.5E-54 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HRM2_RS08880 6c0f64c1e84a9508938d5935abd6158b 229 Hamap MF_01393 ATP synthase subunit a [atpB]. 1 228 16.132 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HRM2_RS08880 6c0f64c1e84a9508938d5935abd6158b 229 Gene3D G3DSA:1.20.120.220 76 227 2.0E-45 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HRM2_RS08880 6c0f64c1e84a9508938d5935abd6158b 229 PANTHER PTHR11410 27 229 1.4E-62 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HRM2_RS13035 2b8f07f787b93312c80fd22edf0d0746 223 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 1 95 5.0E-16 T 22-04-2016 IPR000477 Reverse transcriptase domain HRM2_RS13035 2b8f07f787b93312c80fd22edf0d0746 223 PANTHER PTHR19446:SF107 1 128 1.0E-25 T 22-04-2016 HRM2_RS13035 2b8f07f787b93312c80fd22edf0d0746 223 Pfam PF08388 Group II intron, maturase-specific domain 122 195 5.1E-16 T 22-04-2016 IPR013597 Group II intron, maturase-specific HRM2_RS13035 2b8f07f787b93312c80fd22edf0d0746 223 PANTHER PTHR19446 1 128 1.0E-25 T 22-04-2016 HRM2_RS13035 2b8f07f787b93312c80fd22edf0d0746 223 SUPERFAMILY SSF56672 2 177 2.08E-17 T 22-04-2016 HRM2_RS12480 36e97f7e3d346654d30c306c9043a52a 133 PANTHER PTHR26402 5 122 1.5E-19 T 22-04-2016 HRM2_RS12480 36e97f7e3d346654d30c306c9043a52a 133 SUPERFAMILY SSF52172 3 126 6.4E-24 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS12480 36e97f7e3d346654d30c306c9043a52a 133 Gene3D G3DSA:3.40.50.2300 5 130 2.1E-24 T 22-04-2016 HRM2_RS12480 36e97f7e3d346654d30c306c9043a52a 133 SMART SM00448 5 118 1.3E-12 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS12480 36e97f7e3d346654d30c306c9043a52a 133 Pfam PF00072 Response regulator receiver domain 8 114 6.1E-17 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS13090 e8c7142fb28f7ff873e48c801d3470c4 98 PANTHER PTHR40275:SF1 1 97 2.1E-23 T 22-04-2016 HRM2_RS13090 e8c7142fb28f7ff873e48c801d3470c4 98 PANTHER PTHR40275 1 97 2.1E-23 T 22-04-2016 HRM2_RS13090 e8c7142fb28f7ff873e48c801d3470c4 98 Gene3D G3DSA:1.10.260.40 40 90 1.2E-6 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS13090 e8c7142fb28f7ff873e48c801d3470c4 98 SUPERFAMILY SSF47413 34 90 5.25E-7 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS13090 e8c7142fb28f7ff873e48c801d3470c4 98 TIGRFAM TIGR02684 dnstrm_HI1420: probable addiction module antidote protein 11 91 8.3E-20 T 22-04-2016 IPR014057 Addiction module antidote protein, HI1420 HRM2_RS06325 1910925cdf18d3218c7c699adbe5cf77 407 Pfam PF02491 SHS2 domain inserted in FTSA 82 159 5.6E-33 T 22-04-2016 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 HRM2_RS06325 1910925cdf18d3218c7c699adbe5cf77 407 Pfam PF14450 Cell division protein FtsA 9 184 3.7E-10 T 22-04-2016 HRM2_RS06325 1910925cdf18d3218c7c699adbe5cf77 407 Pfam PF14450 Cell division protein FtsA 204 371 5.6E-20 T 22-04-2016 HRM2_RS06325 1910925cdf18d3218c7c699adbe5cf77 407 PANTHER PTHR32432:SF4 2 403 1.7E-141 T 22-04-2016 HRM2_RS06325 1910925cdf18d3218c7c699adbe5cf77 407 Gene3D G3DSA:3.30.420.40 207 231 3.2E-23 T 22-04-2016 HRM2_RS06325 1910925cdf18d3218c7c699adbe5cf77 407 Gene3D G3DSA:3.30.420.40 295 349 3.2E-23 T 22-04-2016 HRM2_RS06325 1910925cdf18d3218c7c699adbe5cf77 407 Gene3D G3DSA:3.30.1490.110 97 154 3.3E-20 T 22-04-2016 HRM2_RS06325 1910925cdf18d3218c7c699adbe5cf77 407 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 7 375 1.0E-137 T 22-04-2016 IPR020823 Cell division protein FtsA GO:0007049 HRM2_RS06325 1910925cdf18d3218c7c699adbe5cf77 407 PANTHER PTHR32432 2 403 1.7E-141 T 22-04-2016 HRM2_RS06325 1910925cdf18d3218c7c699adbe5cf77 407 Hamap MF_02033 Cell division protein FtsA [ftsA]. 4 407 30.707 T 22-04-2016 IPR020823 Cell division protein FtsA GO:0007049 HRM2_RS06325 1910925cdf18d3218c7c699adbe5cf77 407 SMART SM00842 8 193 4.7E-105 T 22-04-2016 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 HRM2_RS06325 1910925cdf18d3218c7c699adbe5cf77 407 Gene3D G3DSA:3.90.640.10 232 294 2.4E-20 T 22-04-2016 HRM2_RS06325 1910925cdf18d3218c7c699adbe5cf77 407 SUPERFAMILY SSF53067 7 194 1.82E-64 T 22-04-2016 HRM2_RS06325 1910925cdf18d3218c7c699adbe5cf77 407 PIRSF PIRSF003101 1 407 1.3E-144 T 22-04-2016 IPR020823 Cell division protein FtsA GO:0007049 HRM2_RS06325 1910925cdf18d3218c7c699adbe5cf77 407 Gene3D G3DSA:3.30.420.40 155 206 1.6E-25 T 22-04-2016 HRM2_RS06325 1910925cdf18d3218c7c699adbe5cf77 407 Gene3D G3DSA:3.30.420.40 3 80 1.6E-25 T 22-04-2016 HRM2_RS06325 1910925cdf18d3218c7c699adbe5cf77 407 SUPERFAMILY SSF53067 197 375 2.96E-41 T 22-04-2016 HRM2_RS00985 25d9620ba81254a767befc40d6837b90 413 PANTHER PTHR11496 20 301 1.9E-12 T 22-04-2016 HRM2_RS00985 25d9620ba81254a767befc40d6837b90 413 SUPERFAMILY SSF56796 8 381 7.72E-36 T 22-04-2016 HRM2_RS00985 25d9620ba81254a767befc40d6837b90 413 Gene3D G3DSA:1.20.1090.10 186 383 1.1E-12 T 22-04-2016 HRM2_RS00985 25d9620ba81254a767befc40d6837b90 413 Pfam PF00465 Iron-containing alcohol dehydrogenase 15 381 1.1E-38 T 22-04-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 HRM2_RS00985 25d9620ba81254a767befc40d6837b90 413 PANTHER PTHR11496:SF75 20 301 1.9E-12 T 22-04-2016 HRM2_RS00985 25d9620ba81254a767befc40d6837b90 413 Gene3D G3DSA:3.40.50.1970 6 178 1.4E-23 T 22-04-2016 HRM2_RS06400 4fa59adbd02596963db681a714d657ff 320 Gene3D G3DSA:3.40.50.300 2 255 3.6E-80 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06400 4fa59adbd02596963db681a714d657ff 320 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 297 7.7E-13 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HRM2_RS06400 4fa59adbd02596963db681a714d657ff 320 PANTHER PTHR24220 7 315 1.2E-124 T 22-04-2016 HRM2_RS06400 4fa59adbd02596963db681a714d657ff 320 SMART SM00382 40 230 6.9E-18 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS06400 4fa59adbd02596963db681a714d657ff 320 SUPERFAMILY SSF52540 6 252 1.7E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06400 4fa59adbd02596963db681a714d657ff 320 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS06400 4fa59adbd02596963db681a714d657ff 320 Pfam PF00005 ABC transporter 32 181 1.3E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS06400 4fa59adbd02596963db681a714d657ff 320 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 230 316 3.6E-20 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HRM2_RS06400 4fa59adbd02596963db681a714d657ff 320 PANTHER PTHR24220:SF529 7 315 1.2E-124 T 22-04-2016 HRM2_RS18460 128dbcd01d38eb20245c9e44f00cf91d 417 Gene3D G3DSA:2.40.37.10 270 410 4.2E-43 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 HRM2_RS18460 128dbcd01d38eb20245c9e44f00cf91d 417 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 46 278 1.4E-27 T 22-04-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Reactome: REACT_13 HRM2_RS18460 128dbcd01d38eb20245c9e44f00cf91d 417 SUPERFAMILY SSF51419 23 280 9.16E-55 T 22-04-2016 IPR029066 PLP-binding barrel HRM2_RS18460 128dbcd01d38eb20245c9e44f00cf91d 417 Gene3D G3DSA:3.20.20.10 36 269 1.2E-52 T 22-04-2016 IPR029066 PLP-binding barrel HRM2_RS18460 128dbcd01d38eb20245c9e44f00cf91d 417 PANTHER PTHR11482:SF5 14 415 1.6E-123 T 22-04-2016 HRM2_RS18460 128dbcd01d38eb20245c9e44f00cf91d 417 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 283 386 1.5E-13 T 22-04-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 HRM2_RS18460 128dbcd01d38eb20245c9e44f00cf91d 417 SUPERFAMILY SSF50621 258 408 2.93E-43 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 HRM2_RS18460 128dbcd01d38eb20245c9e44f00cf91d 417 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 55 73 - T 22-04-2016 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site Reactome: REACT_13 HRM2_RS18460 128dbcd01d38eb20245c9e44f00cf91d 417 PANTHER PTHR11482 14 415 1.6E-123 T 22-04-2016 HRM2_RS18460 128dbcd01d38eb20245c9e44f00cf91d 417 PRINTS PR01181 Diaminopimelate decarboxylase signature 377 399 5.7E-10 T 22-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 HRM2_RS18460 128dbcd01d38eb20245c9e44f00cf91d 417 PRINTS PR01181 Diaminopimelate decarboxylase signature 73 90 5.7E-10 T 22-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 HRM2_RS18460 128dbcd01d38eb20245c9e44f00cf91d 417 PRINTS PR01181 Diaminopimelate decarboxylase signature 155 164 5.7E-10 T 22-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 HRM2_RS18460 128dbcd01d38eb20245c9e44f00cf91d 417 PRINTS PR01181 Diaminopimelate decarboxylase signature 295 313 5.7E-10 T 22-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 HRM2_RS18460 128dbcd01d38eb20245c9e44f00cf91d 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 268 287 6.9E-15 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 HRM2_RS18460 128dbcd01d38eb20245c9e44f00cf91d 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 55 73 6.9E-15 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 HRM2_RS18460 128dbcd01d38eb20245c9e44f00cf91d 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 75 87 6.9E-15 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 HRM2_RS18460 128dbcd01d38eb20245c9e44f00cf91d 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 367 380 6.9E-15 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 HRM2_RS10080 d01f7976acc3ddc6d565ad8c2c4a02b3 377 PANTHER PTHR11751:SF347 17 375 3.6E-77 T 22-04-2016 HRM2_RS10080 d01f7976acc3ddc6d565ad8c2c4a02b3 377 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 232 241 - T 22-04-2016 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 HRM2_RS10080 d01f7976acc3ddc6d565ad8c2c4a02b3 377 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 13 376 49.755 T 22-04-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9|UniPathway: UPA00031 HRM2_RS10080 d01f7976acc3ddc6d565ad8c2c4a02b3 377 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 15 374 1.5E-89 T 22-04-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9|UniPathway: UPA00031 HRM2_RS10080 d01f7976acc3ddc6d565ad8c2c4a02b3 377 SUPERFAMILY SSF53383 9 376 2.48E-81 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS10080 d01f7976acc3ddc6d565ad8c2c4a02b3 377 Gene3D G3DSA:3.90.1150.10 275 376 8.5E-20 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS10080 d01f7976acc3ddc6d565ad8c2c4a02b3 377 PANTHER PTHR11751 17 375 3.6E-77 T 22-04-2016 HRM2_RS10080 d01f7976acc3ddc6d565ad8c2c4a02b3 377 Pfam PF00155 Aminotransferase class I and II 41 365 2.6E-53 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HRM2_RS10080 d01f7976acc3ddc6d565ad8c2c4a02b3 377 Gene3D G3DSA:3.40.640.10 58 274 1.3E-61 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS13395 536834417f37b5313d476a37cae462eb 153 Gene3D G3DSA:3.10.580.10 2 150 1.3E-34 T 22-04-2016 HRM2_RS13395 536834417f37b5313d476a37cae462eb 153 PANTHER PTHR11911 92 151 3.8E-30 T 22-04-2016 HRM2_RS13395 536834417f37b5313d476a37cae462eb 153 PANTHER PTHR11911 1 60 3.8E-30 T 22-04-2016 HRM2_RS13395 536834417f37b5313d476a37cae462eb 153 Pfam PF00571 CBS domain 94 148 7.8E-13 T 22-04-2016 IPR000644 CBS domain HRM2_RS13395 536834417f37b5313d476a37cae462eb 153 Pfam PF00571 CBS domain 4 55 1.9E-12 T 22-04-2016 IPR000644 CBS domain HRM2_RS13395 536834417f37b5313d476a37cae462eb 153 SUPERFAMILY SSF54631 2 148 1.77E-38 T 22-04-2016 HRM2_RS13395 536834417f37b5313d476a37cae462eb 153 SMART SM00116 11 59 5.3E-6 T 22-04-2016 IPR000644 CBS domain HRM2_RS13395 536834417f37b5313d476a37cae462eb 153 SMART SM00116 101 148 3.6E-11 T 22-04-2016 IPR000644 CBS domain HRM2_RS00065 ae22b9a395323283ad51c771c0887f67 253 SUPERFAMILY SSF56349 11 238 6.59E-33 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HRM2_RS00065 ae22b9a395323283ad51c771c0887f67 253 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 17 94 1.5E-17 T 22-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 HRM2_RS00065 ae22b9a395323283ad51c771c0887f67 253 Gene3D G3DSA:1.10.150.130 11 70 9.4E-4 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal HRM2_RS00065 ae22b9a395323283ad51c771c0887f67 253 Gene3D G3DSA:1.10.443.10 110 238 1.3E-20 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS00065 ae22b9a395323283ad51c771c0887f67 253 Pfam PF00589 Phage integrase family 112 243 1.2E-17 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS00065 ae22b9a395323283ad51c771c0887f67 253 PANTHER PTHR30349:SF5 22 240 1.8E-36 T 22-04-2016 HRM2_RS00065 ae22b9a395323283ad51c771c0887f67 253 PANTHER PTHR30349 22 240 1.8E-36 T 22-04-2016 HRM2_RS06220 ae22b9a395323283ad51c771c0887f67 253 SUPERFAMILY SSF56349 11 238 6.59E-33 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HRM2_RS06220 ae22b9a395323283ad51c771c0887f67 253 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 17 94 1.5E-17 T 22-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 HRM2_RS06220 ae22b9a395323283ad51c771c0887f67 253 Gene3D G3DSA:1.10.150.130 11 70 9.4E-4 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal HRM2_RS06220 ae22b9a395323283ad51c771c0887f67 253 Gene3D G3DSA:1.10.443.10 110 238 1.3E-20 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS06220 ae22b9a395323283ad51c771c0887f67 253 Pfam PF00589 Phage integrase family 112 243 1.2E-17 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS06220 ae22b9a395323283ad51c771c0887f67 253 PANTHER PTHR30349:SF5 22 240 1.8E-36 T 22-04-2016 HRM2_RS06220 ae22b9a395323283ad51c771c0887f67 253 PANTHER PTHR30349 22 240 1.8E-36 T 22-04-2016 HRM2_RS21920 ae22b9a395323283ad51c771c0887f67 253 SUPERFAMILY SSF56349 11 238 6.59E-33 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HRM2_RS21920 ae22b9a395323283ad51c771c0887f67 253 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 17 94 1.5E-17 T 22-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 HRM2_RS21920 ae22b9a395323283ad51c771c0887f67 253 Gene3D G3DSA:1.10.150.130 11 70 9.4E-4 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal HRM2_RS21920 ae22b9a395323283ad51c771c0887f67 253 Gene3D G3DSA:1.10.443.10 110 238 1.3E-20 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS21920 ae22b9a395323283ad51c771c0887f67 253 Pfam PF00589 Phage integrase family 112 243 1.2E-17 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS21920 ae22b9a395323283ad51c771c0887f67 253 PANTHER PTHR30349:SF5 22 240 1.8E-36 T 22-04-2016 HRM2_RS21920 ae22b9a395323283ad51c771c0887f67 253 PANTHER PTHR30349 22 240 1.8E-36 T 22-04-2016 HRM2_RS09785 ae22b9a395323283ad51c771c0887f67 253 SUPERFAMILY SSF56349 11 238 6.59E-33 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HRM2_RS09785 ae22b9a395323283ad51c771c0887f67 253 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 17 94 1.5E-17 T 22-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 HRM2_RS09785 ae22b9a395323283ad51c771c0887f67 253 Gene3D G3DSA:1.10.150.130 11 70 9.4E-4 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal HRM2_RS09785 ae22b9a395323283ad51c771c0887f67 253 Gene3D G3DSA:1.10.443.10 110 238 1.3E-20 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS09785 ae22b9a395323283ad51c771c0887f67 253 Pfam PF00589 Phage integrase family 112 243 1.2E-17 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS09785 ae22b9a395323283ad51c771c0887f67 253 PANTHER PTHR30349:SF5 22 240 1.8E-36 T 22-04-2016 HRM2_RS09785 ae22b9a395323283ad51c771c0887f67 253 PANTHER PTHR30349 22 240 1.8E-36 T 22-04-2016 HRM2_RS23450 43967f701c0a233b9056fc42afbe2894 452 PANTHER PTHR30026:SF4 14 449 6.8E-58 T 22-04-2016 HRM2_RS23450 43967f701c0a233b9056fc42afbe2894 452 Pfam PF02321 Outer membrane efflux protein 265 447 1.5E-36 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS23450 43967f701c0a233b9056fc42afbe2894 452 Pfam PF02321 Outer membrane efflux protein 36 242 3.4E-25 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS23450 43967f701c0a233b9056fc42afbe2894 452 SUPERFAMILY SSF56954 11 449 1.96E-89 T 22-04-2016 HRM2_RS23450 43967f701c0a233b9056fc42afbe2894 452 PANTHER PTHR30026 14 449 6.8E-58 T 22-04-2016 HRM2_RS23450 43967f701c0a233b9056fc42afbe2894 452 Gene3D G3DSA:1.20.1600.10 23 449 2.0E-77 T 22-04-2016 HRM2_RS24750 c5605e3545bd83c5ca6de0deef973fdd 142 Gene3D G3DSA:1.10.3850.10 2 113 4.8E-36 T 22-04-2016 HRM2_RS24750 c5605e3545bd83c5ca6de0deef973fdd 142 SUPERFAMILY SSF82866 2 112 9.68E-23 T 22-04-2016 HRM2_RS24750 c5605e3545bd83c5ca6de0deef973fdd 142 PRINTS PR00702 Acriflavin resistance protein family signature 3 27 1.0E-15 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS24750 c5605e3545bd83c5ca6de0deef973fdd 142 PRINTS PR00702 Acriflavin resistance protein family signature 59 82 1.0E-15 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS24750 c5605e3545bd83c5ca6de0deef973fdd 142 PRINTS PR00702 Acriflavin resistance protein family signature 84 107 1.0E-15 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS24750 c5605e3545bd83c5ca6de0deef973fdd 142 PANTHER PTHR32063 1 112 6.8E-62 T 22-04-2016 HRM2_RS24750 c5605e3545bd83c5ca6de0deef973fdd 142 Pfam PF00873 AcrB/AcrD/AcrF family 2 115 6.8E-30 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS24750 c5605e3545bd83c5ca6de0deef973fdd 142 PANTHER PTHR32063:SF19 1 112 6.8E-62 T 22-04-2016 HRM2_RS07790 11f84a32385ce3701c0ceea7c49a67ed 506 SMART SM00729 188 407 1.3E-18 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS07790 11f84a32385ce3701c0ceea7c49a67ed 506 Pfam PF04055 Radical SAM superfamily 194 357 1.2E-16 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS07790 11f84a32385ce3701c0ceea7c49a67ed 506 PANTHER PTHR11918 29 399 1.3E-47 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein HRM2_RS07790 11f84a32385ce3701c0ceea7c49a67ed 506 Gene3D G3DSA:3.80.30.20 190 398 4.4E-38 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe HRM2_RS07790 11f84a32385ce3701c0ceea7c49a67ed 506 SUPERFAMILY SSF102114 174 397 7.72E-34 T 22-04-2016 HRM2_RS07790 11f84a32385ce3701c0ceea7c49a67ed 506 PANTHER PTHR11918:SF64 29 399 1.3E-47 T 22-04-2016 HRM2_RS21425 b567e221c8809334b32bf555b429ffdf 378 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 32 377 1.9E-72 T 22-04-2016 IPR010327 FldB/FldC dehydratase alpha/beta subunit HRM2_RS21425 b567e221c8809334b32bf555b429ffdf 378 PANTHER PTHR30548:SF6 11 377 1.4E-118 T 22-04-2016 HRM2_RS21425 b567e221c8809334b32bf555b429ffdf 378 PANTHER PTHR30548 11 377 1.4E-118 T 22-04-2016 HRM2_RS06660 1b25580537a847cd927ab0ed4ba8ec6c 426 SUPERFAMILY SSF56300 154 425 1.39E-50 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS06660 1b25580537a847cd927ab0ed4ba8ec6c 426 Gene3D G3DSA:2.60.40.380 50 149 2.3E-12 T 22-04-2016 IPR015914 Purple acid phosphatase, N-terminal GO:0003993|GO:0046872 HRM2_RS06660 1b25580537a847cd927ab0ed4ba8ec6c 426 SUPERFAMILY SSF49363 42 148 4.71E-16 T 22-04-2016 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 HRM2_RS06660 1b25580537a847cd927ab0ed4ba8ec6c 426 Pfam PF00149 Calcineurin-like phosphoesterase 174 346 5.6E-17 T 22-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 HRM2_RS06660 1b25580537a847cd927ab0ed4ba8ec6c 426 PANTHER PTHR22953 47 367 4.6E-53 T 22-04-2016 HRM2_RS06660 1b25580537a847cd927ab0ed4ba8ec6c 426 Gene3D G3DSA:3.60.21.10 153 426 1.9E-59 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS06660 1b25580537a847cd927ab0ed4ba8ec6c 426 Pfam PF16656 Purple acid Phosphatase, N-terminal domain 50 147 2.7E-18 T 22-04-2016 IPR015914 Purple acid phosphatase, N-terminal GO:0003993|GO:0046872 HRM2_RS06660 1b25580537a847cd927ab0ed4ba8ec6c 426 PANTHER PTHR22953:SF0 47 367 4.6E-53 T 22-04-2016 HRM2_RS11460 5268b0f430a8ba0cf67b3c3029248768 739 PANTHER PTHR30258:SF1 15 615 1.7E-217 T 22-04-2016 HRM2_RS11460 5268b0f430a8ba0cf67b3c3029248768 739 TIGRFAM TIGR02538 type_IV_pilB: type IV-A pilus assembly ATPase PilB 28 605 9.1E-226 T 22-04-2016 IPR013374 ATPase, type IV, pilus assembly, PilB GO:0005524|GO:0008565|GO:0009297 HRM2_RS11460 5268b0f430a8ba0cf67b3c3029248768 739 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 424 438 - T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 HRM2_RS11460 5268b0f430a8ba0cf67b3c3029248768 739 Gene3D G3DSA:2.60.120.10 620 729 5.7E-20 T 22-04-2016 IPR014710 RmlC-like jelly roll fold HRM2_RS11460 5268b0f430a8ba0cf67b3c3029248768 739 Gene3D G3DSA:3.30.450.90 211 329 9.0E-48 T 22-04-2016 HRM2_RS11460 5268b0f430a8ba0cf67b3c3029248768 739 SUPERFAMILY SSF52540 219 603 1.18E-97 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11460 5268b0f430a8ba0cf67b3c3029248768 739 Gene3D G3DSA:3.40.50.300 336 605 1.4E-98 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11460 5268b0f430a8ba0cf67b3c3029248768 739 SUPERFAMILY SSF51206 614 720 1.23E-20 T 22-04-2016 IPR018490 Cyclic nucleotide-binding-like HRM2_RS11460 5268b0f430a8ba0cf67b3c3029248768 739 PANTHER PTHR30258 15 615 1.7E-217 T 22-04-2016 HRM2_RS11460 5268b0f430a8ba0cf67b3c3029248768 739 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 61 167 3.5E-22 T 22-04-2016 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 HRM2_RS11460 5268b0f430a8ba0cf67b3c3029248768 739 Pfam PF00027 Cyclic nucleotide-binding domain 622 705 2.7E-14 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain HRM2_RS11460 5268b0f430a8ba0cf67b3c3029248768 739 SUPERFAMILY SSF160246 25 162 2.49E-32 T 22-04-2016 HRM2_RS11460 5268b0f430a8ba0cf67b3c3029248768 739 SMART SM00100 598 717 8.0E-9 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain HRM2_RS11460 5268b0f430a8ba0cf67b3c3029248768 739 SMART SM00382 357 499 2.6E-4 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS11460 5268b0f430a8ba0cf67b3c3029248768 739 Pfam PF00437 Type II/IV secretion system protein 230 496 3.9E-77 T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 HRM2_RS11280 fb75c2bc3ae9a882b93b0ae6aa26376c 375 Gene3D G3DSA:1.10.1060.10 234 339 1.9E-8 T 22-04-2016 HRM2_RS11280 fb75c2bc3ae9a882b93b0ae6aa26376c 375 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 253 264 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS11280 fb75c2bc3ae9a882b93b0ae6aa26376c 375 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 316 327 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS11280 fb75c2bc3ae9a882b93b0ae6aa26376c 375 Pfam PF04432 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus 83 201 8.0E-6 T 22-04-2016 IPR007525 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal HRM2_RS11280 fb75c2bc3ae9a882b93b0ae6aa26376c 375 SUPERFAMILY SSF46548 250 341 1.73E-12 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS02300 baf7c32190abc211448e6eb4332a0236 1024 Gene3D G3DSA:2.40.30.10 920 1016 5.3E-31 T 22-04-2016 HRM2_RS02300 baf7c32190abc211448e6eb4332a0236 1024 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 520 677 2.8E-33 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HRM2_RS02300 baf7c32190abc211448e6eb4332a0236 1024 SUPERFAMILY SSF52156 798 925 2.09E-34 T 22-04-2016 IPR023115 Translation initiation factor IF- 2, domain 3 HRM2_RS02300 baf7c32190abc211448e6eb4332a0236 1024 PANTHER PTHR23115:SF184 500 846 7.2E-196 T 22-04-2016 HRM2_RS02300 baf7c32190abc211448e6eb4332a0236 1024 PANTHER PTHR23115:SF184 871 1022 7.2E-196 T 22-04-2016 HRM2_RS02300 baf7c32190abc211448e6eb4332a0236 1024 SUPERFAMILY SSF52540 511 690 1.26E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02300 baf7c32190abc211448e6eb4332a0236 1024 ProSitePatterns PS01176 Initiation factor 2 signature. 970 992 - T 22-04-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 HRM2_RS02300 baf7c32190abc211448e6eb4332a0236 1024 SUPERFAMILY SSF50447 921 1015 6.86E-26 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain HRM2_RS02300 baf7c32190abc211448e6eb4332a0236 1024 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 50 4.4E-15 T 22-04-2016 IPR006847 Translation initiation factor IF-2, N-terminal HRM2_RS02300 baf7c32190abc211448e6eb4332a0236 1024 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 446 492 8.0E-14 T 22-04-2016 IPR006847 Translation initiation factor IF-2, N-terminal HRM2_RS02300 baf7c32190abc211448e6eb4332a0236 1024 Pfam PF11987 Translation-initiation factor 2 804 908 1.4E-36 T 22-04-2016 IPR023115 Translation initiation factor IF- 2, domain 3 HRM2_RS02300 baf7c32190abc211448e6eb4332a0236 1024 Gene3D G3DSA:2.40.30.10 689 782 2.7E-18 T 22-04-2016 HRM2_RS02300 baf7c32190abc211448e6eb4332a0236 1024 Gene3D G3DSA:3.40.50.10050 819 896 2.0E-24 T 22-04-2016 IPR023115 Translation initiation factor IF- 2, domain 3 HRM2_RS02300 baf7c32190abc211448e6eb4332a0236 1024 Gene3D G3DSA:3.40.50.300 517 677 1.3E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02300 baf7c32190abc211448e6eb4332a0236 1024 SUPERFAMILY SSF50447 690 772 1.19E-20 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain HRM2_RS02300 baf7c32190abc211448e6eb4332a0236 1024 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 1017 17.066 T 22-04-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 HRM2_RS02300 baf7c32190abc211448e6eb4332a0236 1024 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 434 1017 4.3E-245 T 22-04-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 HRM2_RS02300 baf7c32190abc211448e6eb4332a0236 1024 Pfam PF00009 Elongation factor Tu GTP binding domain 523 678 1.6E-34 T 22-04-2016 HRM2_RS02300 baf7c32190abc211448e6eb4332a0236 1024 PANTHER PTHR23115 500 846 7.2E-196 T 22-04-2016 HRM2_RS02300 baf7c32190abc211448e6eb4332a0236 1024 PANTHER PTHR23115 871 1022 7.2E-196 T 22-04-2016 HRM2_RS13695 e9cc646ff9f58907c5bc4aef983e0d36 132 Pfam PF13633 Prokaryotic N-terminal methylation site 17 41 1.4E-9 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site HRM2_RS13695 e9cc646ff9f58907c5bc4aef983e0d36 132 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 17 38 1.2E-6 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site HRM2_RS13695 e9cc646ff9f58907c5bc4aef983e0d36 132 PANTHER PTHR38779 12 132 2.9E-12 T 22-04-2016 HRM2_RS16620 4db3fdea139b0fa4ae8140e3f3bf9dd3 469 ProSitePatterns PS00216 Sugar transport proteins signature 1. 70 87 - T 22-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 HRM2_RS16620 4db3fdea139b0fa4ae8140e3f3bf9dd3 469 Pfam PF07690 Major Facilitator Superfamily 24 402 2.3E-14 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS16620 4db3fdea139b0fa4ae8140e3f3bf9dd3 469 Gene3D G3DSA:1.20.1250.20 32 229 6.9E-16 T 22-04-2016 HRM2_RS16620 4db3fdea139b0fa4ae8140e3f3bf9dd3 469 PANTHER PTHR23530:SF1 11 176 1.1E-16 T 22-04-2016 HRM2_RS16620 4db3fdea139b0fa4ae8140e3f3bf9dd3 469 PANTHER PTHR23530:SF1 196 456 1.1E-16 T 22-04-2016 HRM2_RS16620 4db3fdea139b0fa4ae8140e3f3bf9dd3 469 PANTHER PTHR23530 11 176 1.1E-16 T 22-04-2016 HRM2_RS16620 4db3fdea139b0fa4ae8140e3f3bf9dd3 469 PANTHER PTHR23530 196 456 1.1E-16 T 22-04-2016 HRM2_RS16620 4db3fdea139b0fa4ae8140e3f3bf9dd3 469 SUPERFAMILY SSF103473 25 464 7.32E-28 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS18995 cd7a668b9ced07f59d4093b193f9db8e 577 Pfam PF01039 Carboxyl transferase domain 55 570 6.7E-100 T 22-04-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 HRM2_RS18995 cd7a668b9ced07f59d4093b193f9db8e 577 Gene3D G3DSA:3.90.226.10 293 572 4.1E-43 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS18995 cd7a668b9ced07f59d4093b193f9db8e 577 PANTHER PTHR22855:SF13 25 366 4.5E-109 T 22-04-2016 HRM2_RS18995 cd7a668b9ced07f59d4093b193f9db8e 577 PANTHER PTHR22855:SF13 382 574 4.5E-109 T 22-04-2016 HRM2_RS18995 cd7a668b9ced07f59d4093b193f9db8e 577 SUPERFAMILY SSF52096 49 241 5.33E-37 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS18995 cd7a668b9ced07f59d4093b193f9db8e 577 Gene3D G3DSA:1.20.5.680 1 58 1.8E-17 T 22-04-2016 HRM2_RS18995 cd7a668b9ced07f59d4093b193f9db8e 577 Gene3D G3DSA:3.90.226.10 59 237 7.2E-34 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS18995 cd7a668b9ced07f59d4093b193f9db8e 577 PANTHER PTHR22855 25 366 4.5E-109 T 22-04-2016 HRM2_RS18995 cd7a668b9ced07f59d4093b193f9db8e 577 PANTHER PTHR22855 382 574 4.5E-109 T 22-04-2016 HRM2_RS18995 cd7a668b9ced07f59d4093b193f9db8e 577 SUPERFAMILY SSF52096 292 573 7.46E-49 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS19060 cd7a668b9ced07f59d4093b193f9db8e 577 Pfam PF01039 Carboxyl transferase domain 55 570 6.7E-100 T 22-04-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 HRM2_RS19060 cd7a668b9ced07f59d4093b193f9db8e 577 Gene3D G3DSA:3.90.226.10 293 572 4.1E-43 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS19060 cd7a668b9ced07f59d4093b193f9db8e 577 PANTHER PTHR22855:SF13 25 366 4.5E-109 T 22-04-2016 HRM2_RS19060 cd7a668b9ced07f59d4093b193f9db8e 577 PANTHER PTHR22855:SF13 382 574 4.5E-109 T 22-04-2016 HRM2_RS19060 cd7a668b9ced07f59d4093b193f9db8e 577 SUPERFAMILY SSF52096 49 241 5.33E-37 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS19060 cd7a668b9ced07f59d4093b193f9db8e 577 Gene3D G3DSA:1.20.5.680 1 58 1.8E-17 T 22-04-2016 HRM2_RS19060 cd7a668b9ced07f59d4093b193f9db8e 577 Gene3D G3DSA:3.90.226.10 59 237 7.2E-34 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS19060 cd7a668b9ced07f59d4093b193f9db8e 577 PANTHER PTHR22855 25 366 4.5E-109 T 22-04-2016 HRM2_RS19060 cd7a668b9ced07f59d4093b193f9db8e 577 PANTHER PTHR22855 382 574 4.5E-109 T 22-04-2016 HRM2_RS19060 cd7a668b9ced07f59d4093b193f9db8e 577 SUPERFAMILY SSF52096 292 573 7.46E-49 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS13275 c8745986ec019eb633368900ad63eb4e 648 SUPERFAMILY SSF52374 5 348 1.64E-107 T 22-04-2016 HRM2_RS13275 c8745986ec019eb633368900ad63eb4e 648 Pfam PF01588 Putative tRNA binding domain 553 645 5.5E-25 T 22-04-2016 IPR002547 tRNA-binding domain GO:0000049 Reactome: REACT_71 HRM2_RS13275 c8745986ec019eb633368900ad63eb4e 648 Gene3D G3DSA:1.10.730.10 338 513 5.1E-47 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS13275 c8745986ec019eb633368900ad63eb4e 648 PANTHER PTHR11946:SF1 2 604 1.2E-243 T 22-04-2016 HRM2_RS13275 c8745986ec019eb633368900ad63eb4e 648 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 8 513 2.8E-145 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 HRM2_RS13275 c8745986ec019eb633368900ad63eb4e 648 SUPERFAMILY SSF50249 546 647 1.91E-27 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS13275 c8745986ec019eb633368900ad63eb4e 648 PANTHER PTHR11946 2 604 1.2E-243 T 22-04-2016 HRM2_RS13275 c8745986ec019eb633368900ad63eb4e 648 Gene3D G3DSA:2.170.220.10 118 227 4.3E-40 T 22-04-2016 HRM2_RS13275 c8745986ec019eb633368900ad63eb4e 648 PRINTS PR01041 Methionyl-tRNA synthetase signature 257 272 5.5E-29 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 HRM2_RS13275 c8745986ec019eb633368900ad63eb4e 648 PRINTS PR01041 Methionyl-tRNA synthetase signature 226 237 5.5E-29 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 HRM2_RS13275 c8745986ec019eb633368900ad63eb4e 648 PRINTS PR01041 Methionyl-tRNA synthetase signature 349 360 5.5E-29 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 HRM2_RS13275 c8745986ec019eb633368900ad63eb4e 648 PRINTS PR01041 Methionyl-tRNA synthetase signature 89 100 5.5E-29 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 HRM2_RS13275 c8745986ec019eb633368900ad63eb4e 648 PRINTS PR01041 Methionyl-tRNA synthetase signature 9 22 5.5E-29 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 HRM2_RS13275 c8745986ec019eb633368900ad63eb4e 648 PRINTS PR01041 Methionyl-tRNA synthetase signature 41 55 5.5E-29 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 HRM2_RS13275 c8745986ec019eb633368900ad63eb4e 648 SUPERFAMILY SSF47323 354 517 7.66E-38 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS13275 c8745986ec019eb633368900ad63eb4e 648 Gene3D G3DSA:2.40.50.140 540 647 2.7E-35 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS13275 c8745986ec019eb633368900ad63eb4e 648 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 512 43.625 T 22-04-2016 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HRM2_RS13275 c8745986ec019eb633368900ad63eb4e 648 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 525 648 1.6E-37 T 22-04-2016 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HRM2_RS13275 c8745986ec019eb633368900ad63eb4e 648 Gene3D G3DSA:3.40.50.620 228 336 1.2E-69 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS13275 c8745986ec019eb633368900ad63eb4e 648 Gene3D G3DSA:3.40.50.620 6 115 1.2E-69 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS13275 c8745986ec019eb633368900ad63eb4e 648 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 126 1.4E-6 T 22-04-2016 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 HRM2_RS13275 c8745986ec019eb633368900ad63eb4e 648 Pfam PF08264 Anticodon-binding domain of tRNA 388 471 4.1E-8 T 22-04-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 HRM2_RS13275 c8745986ec019eb633368900ad63eb4e 648 Pfam PF09334 tRNA synthetases class I (M) 140 361 3.4E-59 T 22-04-2016 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS12035 70315ed30bb00cdd93c6894a497692f2 411 SUPERFAMILY SSF118215 5 389 4.05E-115 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HRM2_RS12035 70315ed30bb00cdd93c6894a497692f2 411 Pfam PF00375 Sodium:dicarboxylate symporter family 5 388 4.5E-126 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HRM2_RS12035 70315ed30bb00cdd93c6894a497692f2 411 PRINTS PR00173 Glutamate-aspartate symporter signature 281 307 1.7E-41 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HRM2_RS12035 70315ed30bb00cdd93c6894a497692f2 411 PRINTS PR00173 Glutamate-aspartate symporter signature 206 225 1.7E-41 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HRM2_RS12035 70315ed30bb00cdd93c6894a497692f2 411 PRINTS PR00173 Glutamate-aspartate symporter signature 70 95 1.7E-41 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HRM2_RS12035 70315ed30bb00cdd93c6894a497692f2 411 PRINTS PR00173 Glutamate-aspartate symporter signature 180 199 1.7E-41 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HRM2_RS12035 70315ed30bb00cdd93c6894a497692f2 411 PRINTS PR00173 Glutamate-aspartate symporter signature 3 23 1.7E-41 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HRM2_RS12035 70315ed30bb00cdd93c6894a497692f2 411 PRINTS PR00173 Glutamate-aspartate symporter signature 316 335 1.7E-41 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HRM2_RS12035 70315ed30bb00cdd93c6894a497692f2 411 PRINTS PR00173 Glutamate-aspartate symporter signature 343 363 1.7E-41 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HRM2_RS12035 70315ed30bb00cdd93c6894a497692f2 411 Gene3D G3DSA:1.10.3860.10 2 394 1.3E-129 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HRM2_RS12035 70315ed30bb00cdd93c6894a497692f2 411 PANTHER PTHR11958 1 409 1.4E-147 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HRM2_RS25545 b8a904c8e07ef0d8bbe62451f9b97a3a 676 Gene3D G3DSA:1.10.287.950 410 620 6.8E-46 T 22-04-2016 HRM2_RS25545 b8a904c8e07ef0d8bbe62451f9b97a3a 676 SUPERFAMILY SSF58104 341 657 3.01E-60 T 22-04-2016 HRM2_RS25545 b8a904c8e07ef0d8bbe62451f9b97a3a 676 Pfam PF00672 HAMP domain 300 369 4.2E-11 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS25545 b8a904c8e07ef0d8bbe62451f9b97a3a 676 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 416 445 6.5E-22 T 22-04-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HRM2_RS25545 b8a904c8e07ef0d8bbe62451f9b97a3a 676 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 493 520 6.5E-22 T 22-04-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HRM2_RS25545 b8a904c8e07ef0d8bbe62451f9b97a3a 676 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 522 551 6.5E-22 T 22-04-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HRM2_RS25545 b8a904c8e07ef0d8bbe62451f9b97a3a 676 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 570 599 6.5E-22 T 22-04-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HRM2_RS25545 b8a904c8e07ef0d8bbe62451f9b97a3a 676 PANTHER PTHR32089 286 666 6.3E-88 T 22-04-2016 HRM2_RS25545 b8a904c8e07ef0d8bbe62451f9b97a3a 676 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 396 655 2.0E-4 T 22-04-2016 HRM2_RS25545 b8a904c8e07ef0d8bbe62451f9b97a3a 676 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 458 662 1.9E-31 T 22-04-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HRM2_RS25545 b8a904c8e07ef0d8bbe62451f9b97a3a 676 SMART SM00283 388 663 1.7E-48 T 22-04-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HRM2_RS25545 b8a904c8e07ef0d8bbe62451f9b97a3a 676 SMART SM00304 319 373 2.5E-9 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS22980 a4bec0327be58abd4b4fa8eff1278a54 576 SMART SM00028 530 563 0.056 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS22980 a4bec0327be58abd4b4fa8eff1278a54 576 SMART SM00028 462 495 0.61 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS22980 a4bec0327be58abd4b4fa8eff1278a54 576 SMART SM00028 425 458 0.29 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS22980 a4bec0327be58abd4b4fa8eff1278a54 576 SMART SM00028 496 529 7.9E-7 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS22980 a4bec0327be58abd4b4fa8eff1278a54 576 Pfam PF13181 Tetratricopeptide repeat 432 457 0.022 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS22980 a4bec0327be58abd4b4fa8eff1278a54 576 Pfam PF13181 Tetratricopeptide repeat 535 562 0.022 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS22980 a4bec0327be58abd4b4fa8eff1278a54 576 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 77 382 4.9E-72 T 22-04-2016 IPR003776 YcaO-like domain HRM2_RS22980 a4bec0327be58abd4b4fa8eff1278a54 576 SUPERFAMILY SSF48452 406 564 1.63E-30 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS22980 a4bec0327be58abd4b4fa8eff1278a54 576 Gene3D G3DSA:1.25.40.10 407 562 5.1E-30 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS22980 a4bec0327be58abd4b4fa8eff1278a54 576 Pfam PF00515 Tetratricopeptide repeat 497 528 1.2E-8 T 22-04-2016 IPR001440 Tetratricopeptide repeat 1 GO:0005515 HRM2_RS22980 a4bec0327be58abd4b4fa8eff1278a54 576 PANTHER PTHR23083 406 573 4.3E-27 T 22-04-2016 HRM2_RS22980 a4bec0327be58abd4b4fa8eff1278a54 576 TIGRFAM TIGR00702 TIGR00702: YcaO-type kinase domain 23 294 3.4E-33 T 22-04-2016 IPR003776 YcaO-like domain HRM2_RS14485 9c7f16fbe93befea4324ecd535742f36 359 TIGRFAM TIGR00238 TIGR00238: KamA family protein 3 317 7.9E-81 T 22-04-2016 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase HRM2_RS14485 9c7f16fbe93befea4324ecd535742f36 359 PIRSF PIRSF004911 1 357 7.2E-121 T 22-04-2016 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase HRM2_RS14485 9c7f16fbe93befea4324ecd535742f36 359 Gene3D G3DSA:3.20.20.70 100 278 3.9E-13 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS14485 9c7f16fbe93befea4324ecd535742f36 359 Pfam PF12544 Lysine-2,3-aminomutase 302 351 1.7E-6 T 22-04-2016 IPR025895 Lysine-2,3-aminomutase, C-terminal domain HRM2_RS14485 9c7f16fbe93befea4324ecd535742f36 359 PANTHER PTHR30538:SF1 1 357 6.5E-99 T 22-04-2016 HRM2_RS14485 9c7f16fbe93befea4324ecd535742f36 359 PANTHER PTHR30538 1 357 6.5E-99 T 22-04-2016 HRM2_RS14485 9c7f16fbe93befea4324ecd535742f36 359 Pfam PF13394 4Fe-4S single cluster domain 105 195 4.3E-5 T 22-04-2016 HRM2_RS14485 9c7f16fbe93befea4324ecd535742f36 359 SUPERFAMILY SSF102114 99 306 3.14E-21 T 22-04-2016 HRM2_RS00870 ba66d5835c9405deb87575179ebfaf2c 228 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 7 217 2.5E-59 T 22-04-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 HRM2_RS00870 ba66d5835c9405deb87575179ebfaf2c 228 PANTHER PTHR10010:SF14 3 216 3.0E-50 T 22-04-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 HRM2_RS00870 ba66d5835c9405deb87575179ebfaf2c 228 PIRSF PIRSF003107 2 222 2.8E-55 T 22-04-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 HRM2_RS00870 ba66d5835c9405deb87575179ebfaf2c 228 PANTHER PTHR10010 3 216 3.0E-50 T 22-04-2016 HRM2_RS00870 ba66d5835c9405deb87575179ebfaf2c 228 Pfam PF01895 PhoU domain 124 208 2.0E-16 T 22-04-2016 IPR026022 PhoU domain HRM2_RS00870 ba66d5835c9405deb87575179ebfaf2c 228 Pfam PF01895 PhoU domain 20 106 5.0E-20 T 22-04-2016 IPR026022 PhoU domain HRM2_RS00870 ba66d5835c9405deb87575179ebfaf2c 228 SUPERFAMILY SSF109755 7 216 4.6E-55 T 22-04-2016 HRM2_RS00870 ba66d5835c9405deb87575179ebfaf2c 228 Gene3D G3DSA:1.20.58.220 119 217 7.1E-24 T 22-04-2016 HRM2_RS00870 ba66d5835c9405deb87575179ebfaf2c 228 Gene3D G3DSA:1.20.58.220 4 113 1.0E-29 T 22-04-2016 HRM2_RS01060 709fbe5a84c569da8af8a208675947f5 166 PANTHER PTHR30173 9 162 4.6E-26 T 22-04-2016 HRM2_RS01060 709fbe5a84c569da8af8a208675947f5 166 Gene3D G3DSA:1.10.1740.10 10 79 1.5E-12 T 22-04-2016 HRM2_RS01060 709fbe5a84c569da8af8a208675947f5 166 SUPERFAMILY SSF88946 10 83 1.53E-11 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS01060 709fbe5a84c569da8af8a208675947f5 166 Gene3D G3DSA:1.10.10.10 98 163 5.5E-14 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS01060 709fbe5a84c569da8af8a208675947f5 166 Pfam PF04542 Sigma-70 region 2 14 77 3.0E-8 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS01060 709fbe5a84c569da8af8a208675947f5 166 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 159 1.2E-19 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS01060 709fbe5a84c569da8af8a208675947f5 166 SUPERFAMILY SSF88659 80 163 8.6E-13 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS01060 709fbe5a84c569da8af8a208675947f5 166 Pfam PF08281 Sigma-70, region 4 106 157 2.5E-12 T 22-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS00790 1c1c7b8ed4cad7529dbb48ba9be732b6 120 Pfam PF01381 Helix-turn-helix 19 66 3.3E-6 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS00790 1c1c7b8ed4cad7529dbb48ba9be732b6 120 SUPERFAMILY SSF47413 12 66 6.48E-11 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS00790 1c1c7b8ed4cad7529dbb48ba9be732b6 120 Gene3D G3DSA:1.10.260.40 12 66 3.6E-11 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS00790 1c1c7b8ed4cad7529dbb48ba9be732b6 120 SMART SM00530 18 71 2.3E-5 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS11090 23034800a0d0d23d3aa9139b6991ec49 492 Pfam PF00152 tRNA synthetases class II (D, K and N) 151 488 3.4E-81 T 22-04-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS11090 23034800a0d0d23d3aa9139b6991ec49 492 PRINTS PR00982 Lysyl-tRNA synthetase signature 187 197 1.2E-35 T 22-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 HRM2_RS11090 23034800a0d0d23d3aa9139b6991ec49 492 PRINTS PR00982 Lysyl-tRNA synthetase signature 203 219 1.2E-35 T 22-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 HRM2_RS11090 23034800a0d0d23d3aa9139b6991ec49 492 PRINTS PR00982 Lysyl-tRNA synthetase signature 373 389 1.2E-35 T 22-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 HRM2_RS11090 23034800a0d0d23d3aa9139b6991ec49 492 PRINTS PR00982 Lysyl-tRNA synthetase signature 232 245 1.2E-35 T 22-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 HRM2_RS11090 23034800a0d0d23d3aa9139b6991ec49 492 PRINTS PR00982 Lysyl-tRNA synthetase signature 250 267 1.2E-35 T 22-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 HRM2_RS11090 23034800a0d0d23d3aa9139b6991ec49 492 SUPERFAMILY SSF55681 150 489 1.65E-117 T 22-04-2016 HRM2_RS11090 23034800a0d0d23d3aa9139b6991ec49 492 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 10 492 42.689 T 22-04-2016 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6 HRM2_RS11090 23034800a0d0d23d3aa9139b6991ec49 492 Gene3D G3DSA:2.40.50.140 7 143 1.9E-39 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS11090 23034800a0d0d23d3aa9139b6991ec49 492 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 5 490 6.9E-196 T 22-04-2016 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6 HRM2_RS11090 23034800a0d0d23d3aa9139b6991ec49 492 PANTHER PTHR22594:SF4 3 489 1.9E-245 T 22-04-2016 HRM2_RS11090 23034800a0d0d23d3aa9139b6991ec49 492 SUPERFAMILY SSF50249 4 143 1.0E-33 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS11090 23034800a0d0d23d3aa9139b6991ec49 492 Gene3D G3DSA:3.30.930.10 145 487 1.8E-120 T 22-04-2016 HRM2_RS11090 23034800a0d0d23d3aa9139b6991ec49 492 Pfam PF01336 OB-fold nucleic acid binding domain 58 134 1.8E-12 T 22-04-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 HRM2_RS11090 23034800a0d0d23d3aa9139b6991ec49 492 PANTHER PTHR22594 3 489 1.9E-245 T 22-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS03030 d902df24ef2f5b7968af73b9db36834a 471 Pfam PF13353 4Fe-4S single cluster domain 74 168 3.7E-7 T 22-04-2016 HRM2_RS03030 d902df24ef2f5b7968af73b9db36834a 471 Pfam PF04055 Radical SAM superfamily 85 199 8.5E-10 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS03030 d902df24ef2f5b7968af73b9db36834a 471 PANTHER PTHR22976:SF15 65 187 5.6E-23 T 22-04-2016 HRM2_RS03030 d902df24ef2f5b7968af73b9db36834a 471 Gene3D G3DSA:3.20.20.70 80 328 1.9E-24 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS03030 d902df24ef2f5b7968af73b9db36834a 471 SUPERFAMILY SSF102114 79 312 3.79E-25 T 22-04-2016 HRM2_RS03030 d902df24ef2f5b7968af73b9db36834a 471 PANTHER PTHR22976 65 187 5.6E-23 T 22-04-2016 HRM2_RS05295 ab32aa178da3375133fa3d09d9906020 182 PANTHER PTHR10245 11 182 6.2E-31 T 22-04-2016 HRM2_RS05295 ab32aa178da3375133fa3d09d9906020 182 Pfam PF07883 Cupin domain 123 178 1.4E-15 T 22-04-2016 IPR013096 Cupin 2, conserved barrel HRM2_RS05295 ab32aa178da3375133fa3d09d9906020 182 SMART SM00530 14 69 1.4E-5 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS05295 ab32aa178da3375133fa3d09d9906020 182 Gene3D G3DSA:2.60.120.10 105 182 3.5E-23 T 22-04-2016 IPR014710 RmlC-like jelly roll fold HRM2_RS05295 ab32aa178da3375133fa3d09d9906020 182 SUPERFAMILY SSF51182 87 179 2.45E-23 T 22-04-2016 IPR011051 RmlC-like cupin domain HRM2_RS05295 ab32aa178da3375133fa3d09d9906020 182 SUPERFAMILY SSF47413 8 73 1.75E-12 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS05295 ab32aa178da3375133fa3d09d9906020 182 Pfam PF12844 Helix-turn-helix domain 12 72 2.5E-7 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS05295 ab32aa178da3375133fa3d09d9906020 182 PANTHER PTHR10245:SF9 11 182 6.2E-31 T 22-04-2016 HRM2_RS05295 ab32aa178da3375133fa3d09d9906020 182 Gene3D G3DSA:1.10.260.40 11 104 7.4E-17 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS19155 fd8c0645cfc668e6fe88522f320e7712 337 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 35 287 1.1E-64 T 22-04-2016 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 HRM2_RS19155 fd8c0645cfc668e6fe88522f320e7712 337 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 34 314 2.0E-77 T 22-04-2016 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 HRM2_RS19155 fd8c0645cfc668e6fe88522f320e7712 337 PANTHER PTHR33376 1 337 1.1E-74 T 22-04-2016 HRM2_RS19155 fd8c0645cfc668e6fe88522f320e7712 337 PIRSF PIRSF006470 1 334 9.2E-83 T 22-04-2016 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 HRM2_RS19235 6b26f48b2f73040d57e9b383347973a7 495 PANTHER PTHR22773 1 492 8.6E-131 T 22-04-2016 HRM2_RS19235 6b26f48b2f73040d57e9b383347973a7 495 PANTHER PTHR22773:SF56 1 492 8.6E-131 T 22-04-2016 HRM2_RS19235 6b26f48b2f73040d57e9b383347973a7 495 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 328 347 9.6E-8 T 22-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 HRM2_RS19235 6b26f48b2f73040d57e9b383347973a7 495 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 240 264 9.6E-8 T 22-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 HRM2_RS19235 6b26f48b2f73040d57e9b383347973a7 495 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 380 406 9.6E-8 T 22-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 HRM2_RS19235 6b26f48b2f73040d57e9b383347973a7 495 Pfam PF00361 Proton-conducting membrane transporter 126 416 6.3E-51 T 22-04-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: REACT_6305 HRM2_RS09405 016aae5bba80587de11e9f2484a02244 509 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 197 509 3.3E-147 T 22-04-2016 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 HRM2_RS09405 016aae5bba80587de11e9f2484a02244 509 SUPERFAMILY SSF52317 1 221 2.02E-55 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS09405 016aae5bba80587de11e9f2484a02244 509 Pfam PF00958 GMP synthase C terminal domain 417 508 1.6E-45 T 22-04-2016 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 HRM2_RS09405 016aae5bba80587de11e9f2484a02244 509 PRINTS PR00097 Anthranilate synthase component II signature 161 174 2.8E-5 T 22-04-2016 HRM2_RS09405 016aae5bba80587de11e9f2484a02244 509 PRINTS PR00097 Anthranilate synthase component II signature 46 55 2.8E-5 T 22-04-2016 HRM2_RS09405 016aae5bba80587de11e9f2484a02244 509 PRINTS PR00097 Anthranilate synthase component II signature 73 84 2.8E-5 T 22-04-2016 HRM2_RS09405 016aae5bba80587de11e9f2484a02244 509 PANTHER PTHR11922 1 506 2.4E-281 T 22-04-2016 HRM2_RS09405 016aae5bba80587de11e9f2484a02244 509 Pfam PF02540 NAD synthase 204 273 2.9E-7 T 22-04-2016 IPR022310 NAD/GMP synthase HRM2_RS09405 016aae5bba80587de11e9f2484a02244 509 PANTHER PTHR11922:SF2 1 506 2.4E-281 T 22-04-2016 HRM2_RS09405 016aae5bba80587de11e9f2484a02244 509 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 2 189 1.9E-76 T 22-04-2016 IPR004739 GMP synthase, N-terminal GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 HRM2_RS09405 016aae5bba80587de11e9f2484a02244 509 Pfam PF00117 Glutamine amidotransferase class-I 4 184 2.4E-43 T 22-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 HRM2_RS09405 016aae5bba80587de11e9f2484a02244 509 Gene3D G3DSA:3.40.50.620 207 384 3.0E-55 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS09405 016aae5bba80587de11e9f2484a02244 509 SUPERFAMILY SSF52402 177 430 1.39E-51 T 22-04-2016 HRM2_RS09405 016aae5bba80587de11e9f2484a02244 509 PRINTS PR00096 Glutamine amidotransferase superfamily signature 73 84 1.6E-6 T 22-04-2016 HRM2_RS09405 016aae5bba80587de11e9f2484a02244 509 PRINTS PR00096 Glutamine amidotransferase superfamily signature 46 55 1.6E-6 T 22-04-2016 HRM2_RS09405 016aae5bba80587de11e9f2484a02244 509 PRINTS PR00096 Glutamine amidotransferase superfamily signature 161 174 1.6E-6 T 22-04-2016 HRM2_RS09405 016aae5bba80587de11e9f2484a02244 509 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 1 509 53.446 T 22-04-2016 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 HRM2_RS09405 016aae5bba80587de11e9f2484a02244 509 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 43 57 5.7E-7 T 22-04-2016 HRM2_RS09405 016aae5bba80587de11e9f2484a02244 509 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 2 16 5.7E-7 T 22-04-2016 HRM2_RS09405 016aae5bba80587de11e9f2484a02244 509 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 73 89 5.7E-7 T 22-04-2016 HRM2_RS09405 016aae5bba80587de11e9f2484a02244 509 Gene3D G3DSA:3.40.50.880 1 206 7.2E-63 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS09405 016aae5bba80587de11e9f2484a02244 509 Gene3D G3DSA:3.30.300.10 385 509 4.0E-52 T 22-04-2016 HRM2_RS09405 016aae5bba80587de11e9f2484a02244 509 SUPERFAMILY SSF54810 389 509 8.63E-50 T 22-04-2016 HRM2_RS14805 59aacdd1a640c38bf508b6eaaf263018 204 Gene3D G3DSA:3.40.50.150 24 177 4.9E-13 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS14805 59aacdd1a640c38bf508b6eaaf263018 204 Pfam PF08241 Methyltransferase domain 62 112 7.1E-6 T 22-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 HRM2_RS14805 59aacdd1a640c38bf508b6eaaf263018 204 SUPERFAMILY SSF53335 37 177 7.5E-13 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS06310 9feadff9316e5be8ebc10dd7bd99778e 456 SUPERFAMILY SSF53623 92 304 1.14E-69 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HRM2_RS06310 9feadff9316e5be8ebc10dd7bd99778e 456 Gene3D G3DSA:3.90.190.20 311 455 4.0E-56 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HRM2_RS06310 9feadff9316e5be8ebc10dd7bd99778e 456 PANTHER PTHR23135 1 444 8.2E-205 T 22-04-2016 HRM2_RS06310 9feadff9316e5be8ebc10dd7bd99778e 456 SUPERFAMILY SSF53244 308 455 3.82E-50 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HRM2_RS06310 9feadff9316e5be8ebc10dd7bd99778e 456 Pfam PF08245 Mur ligase middle domain 110 289 3.2E-30 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HRM2_RS06310 9feadff9316e5be8ebc10dd7bd99778e 456 Pfam PF01225 Mur ligase family, catalytic domain 7 106 6.9E-24 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 HRM2_RS06310 9feadff9316e5be8ebc10dd7bd99778e 456 PANTHER PTHR23135:SF5 1 444 8.2E-205 T 22-04-2016 HRM2_RS06310 9feadff9316e5be8ebc10dd7bd99778e 456 Gene3D G3DSA:3.40.50.720 7 92 5.8E-34 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS06310 9feadff9316e5be8ebc10dd7bd99778e 456 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 5 456 40.922 T 22-04-2016 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS06310 9feadff9316e5be8ebc10dd7bd99778e 456 Pfam PF02875 Mur ligase family, glutamate ligase domain 309 395 3.7E-24 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HRM2_RS06310 9feadff9316e5be8ebc10dd7bd99778e 456 SUPERFAMILY SSF51984 7 91 1.83E-27 T 22-04-2016 HRM2_RS06310 9feadff9316e5be8ebc10dd7bd99778e 456 Gene3D G3DSA:3.40.1190.10 94 310 2.5E-81 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HRM2_RS06310 9feadff9316e5be8ebc10dd7bd99778e 456 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 7 451 1.7E-168 T 22-04-2016 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS05990 02344ed690ae110ebb4829c5c6c293c0 506 SMART SM00387 390 499 1.0E-32 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS05990 02344ed690ae110ebb4829c5c6c293c0 506 SUPERFAMILY SSF47384 273 345 7.65E-13 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS05990 02344ed690ae110ebb4829c5c6c293c0 506 SMART SM00091 151 219 3.6E-4 T 22-04-2016 IPR000014 PAS domain HRM2_RS05990 02344ed690ae110ebb4829c5c6c293c0 506 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 390 498 9.2E-23 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS05990 02344ed690ae110ebb4829c5c6c293c0 506 Pfam PF00512 His Kinase A (phospho-acceptor) domain 280 345 6.6E-13 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS05990 02344ed690ae110ebb4829c5c6c293c0 506 PRINTS PR00344 Bacterial sensor protein C-terminal signature 483 496 2.0E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS05990 02344ed690ae110ebb4829c5c6c293c0 506 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 477 2.0E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS05990 02344ed690ae110ebb4829c5c6c293c0 506 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 456 2.0E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS05990 02344ed690ae110ebb4829c5c6c293c0 506 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 442 2.0E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS05990 02344ed690ae110ebb4829c5c6c293c0 506 Gene3D G3DSA:3.30.565.10 333 503 4.3E-45 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS05990 02344ed690ae110ebb4829c5c6c293c0 506 SUPERFAMILY SSF55874 336 499 5.11E-42 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS05990 02344ed690ae110ebb4829c5c6c293c0 506 Gene3D G3DSA:1.10.287.130 274 332 9.7E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS05990 02344ed690ae110ebb4829c5c6c293c0 506 PANTHER PTHR24423:SF445 149 506 1.5E-77 T 22-04-2016 HRM2_RS05990 02344ed690ae110ebb4829c5c6c293c0 506 SMART SM00388 280 347 3.5E-13 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS05990 02344ed690ae110ebb4829c5c6c293c0 506 PANTHER PTHR24423 149 506 1.5E-77 T 22-04-2016 HRM2_RS05990 02344ed690ae110ebb4829c5c6c293c0 506 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 149 271 6.2E-12 T 22-04-2016 IPR000014 PAS domain HRM2_RS05990 02344ed690ae110ebb4829c5c6c293c0 506 Gene3D G3DSA:3.30.450.20 144 244 1.3E-13 T 22-04-2016 HRM2_RS05990 02344ed690ae110ebb4829c5c6c293c0 506 SUPERFAMILY SSF55785 141 249 2.09E-12 T 22-04-2016 IPR000014 PAS domain HRM2_RS05990 02344ed690ae110ebb4829c5c6c293c0 506 Pfam PF13426 PAS domain 163 242 2.0E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS19130 7be1390125b9197973f3e43dba657aaa 918 Gene3D G3DSA:1.10.150.120 81 184 2.1E-32 T 22-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 HRM2_RS19130 7be1390125b9197973f3e43dba657aaa 918 SUPERFAMILY SSF47741 90 192 6.8E-32 T 22-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 HRM2_RS19130 7be1390125b9197973f3e43dba657aaa 918 Gene3D G3DSA:3.30.365.10 298 364 3.4E-30 T 22-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 HRM2_RS19130 7be1390125b9197973f3e43dba657aaa 918 Gene3D G3DSA:3.30.365.10 460 533 3.4E-30 T 22-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 HRM2_RS19130 7be1390125b9197973f3e43dba657aaa 918 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 44 52 - T 22-04-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 HRM2_RS19130 7be1390125b9197973f3e43dba657aaa 918 Gene3D G3DSA:3.30.365.10 534 568 2.0E-47 T 22-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 HRM2_RS19130 7be1390125b9197973f3e43dba657aaa 918 Gene3D G3DSA:3.30.365.10 746 906 2.0E-47 T 22-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 HRM2_RS19130 7be1390125b9197973f3e43dba657aaa 918 SMART SM01008 194 309 6.9E-27 T 22-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead HRM2_RS19130 7be1390125b9197973f3e43dba657aaa 918 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 326 844 1.1E-126 T 22-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 HRM2_RS19130 7be1390125b9197973f3e43dba657aaa 918 Gene3D G3DSA:3.30.365.10 629 745 2.5E-18 T 22-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 HRM2_RS19130 7be1390125b9197973f3e43dba657aaa 918 SUPERFAMILY SSF56003 313 905 6.93E-139 T 22-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 HRM2_RS19130 7be1390125b9197973f3e43dba657aaa 918 PANTHER PTHR11908 181 913 1.5E-134 T 22-04-2016 HRM2_RS19130 7be1390125b9197973f3e43dba657aaa 918 SUPERFAMILY SSF54665 175 331 1.7E-35 T 22-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead HRM2_RS19130 7be1390125b9197973f3e43dba657aaa 918 Gene3D G3DSA:3.30.365.10 366 455 5.7E-20 T 22-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 HRM2_RS19130 7be1390125b9197973f3e43dba657aaa 918 Pfam PF01799 [2Fe-2S] binding domain 79 153 7.0E-25 T 22-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 HRM2_RS19130 7be1390125b9197973f3e43dba657aaa 918 Gene3D G3DSA:3.10.20.30 9 80 5.4E-21 T 22-04-2016 IPR012675 Beta-grasp domain HRM2_RS19130 7be1390125b9197973f3e43dba657aaa 918 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 210 309 1.1E-21 T 22-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead HRM2_RS19130 7be1390125b9197973f3e43dba657aaa 918 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 12 63 6.0E-5 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 HRM2_RS19130 7be1390125b9197973f3e43dba657aaa 918 Gene3D G3DSA:3.90.1170.50 185 297 3.2E-31 T 22-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead HRM2_RS19130 7be1390125b9197973f3e43dba657aaa 918 SUPERFAMILY SSF54292 10 93 1.31E-19 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 HRM2_RS02170 c171c4e02b32e4fc326e4947f07d2f97 788 PIRSF PIRSF001174 7 786 0.0 T 22-04-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 HRM2_RS02170 c171c4e02b32e4fc326e4947f07d2f97 788 SUPERFAMILY SSF88697 19 211 1.42E-36 T 22-04-2016 IPR015947 PUA-like domain HRM2_RS02170 c171c4e02b32e4fc326e4947f07d2f97 788 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 20 211 8.5E-32 T 22-04-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 HRM2_RS02170 c171c4e02b32e4fc326e4947f07d2f97 788 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 583 783 2.5E-90 T 22-04-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 HRM2_RS02170 c171c4e02b32e4fc326e4947f07d2f97 788 PANTHER PTHR10046:SF43 7 787 0.0 T 22-04-2016 HRM2_RS02170 c171c4e02b32e4fc326e4947f07d2f97 788 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 684 703 7.5E-51 T 22-04-2016 HRM2_RS02170 c171c4e02b32e4fc326e4947f07d2f97 788 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 366 385 7.5E-51 T 22-04-2016 HRM2_RS02170 c171c4e02b32e4fc326e4947f07d2f97 788 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 606 622 7.5E-51 T 22-04-2016 HRM2_RS02170 c171c4e02b32e4fc326e4947f07d2f97 788 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 737 755 7.5E-51 T 22-04-2016 HRM2_RS02170 c171c4e02b32e4fc326e4947f07d2f97 788 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 714 733 7.5E-51 T 22-04-2016 HRM2_RS02170 c171c4e02b32e4fc326e4947f07d2f97 788 Gene3D G3DSA:3.40.50.300 324 511 7.6E-34 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02170 c171c4e02b32e4fc326e4947f07d2f97 788 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 362 499 5.1E-21 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HRM2_RS02170 c171c4e02b32e4fc326e4947f07d2f97 788 SMART SM00382 358 503 2.9E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS02170 c171c4e02b32e4fc326e4947f07d2f97 788 PANTHER PTHR10046 7 787 0.0 T 22-04-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 HRM2_RS02170 c171c4e02b32e4fc326e4947f07d2f97 788 Gene3D G3DSA:3.30.230.10 602 782 1.3E-71 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HRM2_RS02170 c171c4e02b32e4fc326e4947f07d2f97 788 Gene3D G3DSA:1.10.8.60 512 595 1.5E-27 T 22-04-2016 HRM2_RS02170 c171c4e02b32e4fc326e4947f07d2f97 788 SUPERFAMILY SSF54211 606 781 2.81E-54 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS02170 c171c4e02b32e4fc326e4947f07d2f97 788 Hamap MF_01973 Lon protease [lon]. 20 783 65.867 T 22-04-2016 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 HRM2_RS02170 c171c4e02b32e4fc326e4947f07d2f97 788 TIGRFAM TIGR00763 lon: endopeptidase La 21 782 3.9E-282 T 22-04-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 HRM2_RS02170 c171c4e02b32e4fc326e4947f07d2f97 788 SUPERFAMILY SSF52540 321 593 5.5E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02170 c171c4e02b32e4fc326e4947f07d2f97 788 SMART SM00464 19 212 5.8E-53 T 22-04-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 HRM2_RS06715 b0feccc7b62123b18cf4e2bce0a1077c 369 PANTHER PTHR23305:SF12 1 369 3.9E-183 T 22-04-2016 HRM2_RS06715 b0feccc7b62123b18cf4e2bce0a1077c 369 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 369 4.9E-137 T 22-04-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 HRM2_RS06715 b0feccc7b62123b18cf4e2bce0a1077c 369 Pfam PF01926 50S ribosome-binding GTPase 5 120 1.6E-22 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS06715 b0feccc7b62123b18cf4e2bce0a1077c 369 Gene3D G3DSA:3.10.20.30 274 369 2.0E-45 T 22-04-2016 IPR012675 Beta-grasp domain HRM2_RS06715 b0feccc7b62123b18cf4e2bce0a1077c 369 PIRSF PIRSF006641 1 369 2.5E-148 T 22-04-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 HRM2_RS06715 b0feccc7b62123b18cf4e2bce0a1077c 369 SUPERFAMILY SSF52540 3 305 1.38E-75 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06715 b0feccc7b62123b18cf4e2bce0a1077c 369 Gene3D G3DSA:3.40.50.300 3 130 1.7E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06715 b0feccc7b62123b18cf4e2bce0a1077c 369 Gene3D G3DSA:3.40.50.300 205 273 1.7E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06715 b0feccc7b62123b18cf4e2bce0a1077c 369 PANTHER PTHR23305 1 369 3.9E-183 T 22-04-2016 HRM2_RS06715 b0feccc7b62123b18cf4e2bce0a1077c 369 Gene3D G3DSA:1.10.150.300 131 204 1.6E-19 T 22-04-2016 IPR023192 TGS-like domain HRM2_RS06715 b0feccc7b62123b18cf4e2bce0a1077c 369 Pfam PF06071 Protein of unknown function (DUF933) 285 368 3.9E-37 T 22-04-2016 IPR013029 Domain of unknown function DUF933 HRM2_RS06715 b0feccc7b62123b18cf4e2bce0a1077c 369 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 369 41.538 T 22-04-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 HRM2_RS06715 b0feccc7b62123b18cf4e2bce0a1077c 369 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 1.8E-36 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS06715 b0feccc7b62123b18cf4e2bce0a1077c 369 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 1.8E-36 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS06715 b0feccc7b62123b18cf4e2bce0a1077c 369 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.8E-36 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS06715 b0feccc7b62123b18cf4e2bce0a1077c 369 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 1.8E-36 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS06715 b0feccc7b62123b18cf4e2bce0a1077c 369 SUPERFAMILY SSF81271 285 366 2.62E-33 T 22-04-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 HRM2_RS08425 d1fdfd5489023ce8026a46907b28d0c4 549 PANTHER PTHR11203:SF22 2 549 2.1E-196 T 22-04-2016 IPR004613 Ribonuclease J GO:0003723|GO:0046872 HRM2_RS08425 d1fdfd5489023ce8026a46907b28d0c4 549 Gene3D G3DSA:3.60.15.10 1 249 3.6E-71 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS08425 d1fdfd5489023ce8026a46907b28d0c4 549 PANTHER PTHR11203 2 549 2.1E-196 T 22-04-2016 HRM2_RS08425 d1fdfd5489023ce8026a46907b28d0c4 549 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 2 547 2.8E-181 T 22-04-2016 IPR004613 Ribonuclease J GO:0003723|GO:0046872 HRM2_RS08425 d1fdfd5489023ce8026a46907b28d0c4 549 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 358 386 - T 22-04-2016 IPR001587 Ribonuclease J, conserved site HRM2_RS08425 d1fdfd5489023ce8026a46907b28d0c4 549 Pfam PF00753 Metallo-beta-lactamase superfamily 14 169 2.3E-15 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS08425 d1fdfd5489023ce8026a46907b28d0c4 549 Hamap MF_01491 Ribonuclease J [rnj]. 1 549 42.184 T 22-04-2016 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 HRM2_RS08425 d1fdfd5489023ce8026a46907b28d0c4 549 SUPERFAMILY SSF56281 2 416 2.03E-91 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS08425 d1fdfd5489023ce8026a46907b28d0c4 549 PIRSF PIRSF004803 1 549 3.3E-223 T 22-04-2016 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 HRM2_RS08425 d1fdfd5489023ce8026a46907b28d0c4 549 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 353 403 1.7E-13 T 22-04-2016 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain HRM2_RS08425 d1fdfd5489023ce8026a46907b28d0c4 549 SMART SM00849 14 217 2.9E-20 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS15625 79d1a6558f6770d35046c4e06615e7ad 548 PANTHER PTHR11921:SF24 84 353 2.5E-129 T 22-04-2016 HRM2_RS15625 79d1a6558f6770d35046c4e06615e7ad 548 PANTHER PTHR11921:SF24 375 525 2.5E-129 T 22-04-2016 HRM2_RS15625 79d1a6558f6770d35046c4e06615e7ad 548 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 168 179 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS15625 79d1a6558f6770d35046c4e06615e7ad 548 Pfam PF02754 Cysteine-rich domain 406 467 0.0012 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS15625 79d1a6558f6770d35046c4e06615e7ad 548 SUPERFAMILY SSF46548 75 195 1.26E-14 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS15625 79d1a6558f6770d35046c4e06615e7ad 548 Pfam PF13183 4Fe-4S dicluster domain 91 182 5.3E-9 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS15625 79d1a6558f6770d35046c4e06615e7ad 548 Gene3D G3DSA:1.10.1060.10 73 194 3.5E-12 T 22-04-2016 HRM2_RS15625 79d1a6558f6770d35046c4e06615e7ad 548 PANTHER PTHR11921 84 353 2.5E-129 T 22-04-2016 HRM2_RS15625 79d1a6558f6770d35046c4e06615e7ad 548 PANTHER PTHR11921 375 525 2.5E-129 T 22-04-2016 HRM2_RS24490 18b0e1fd47f4785e99ed572b235ff300 105 PRINTS PR01159 DNA gyrase subunit B signature 89 105 2.1E-11 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS24490 18b0e1fd47f4785e99ed572b235ff300 105 PRINTS PR01159 DNA gyrase subunit B signature 73 85 2.1E-11 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS24490 18b0e1fd47f4785e99ed572b235ff300 105 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 47 105 9.1E-30 T 22-04-2016 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS24490 18b0e1fd47f4785e99ed572b235ff300 105 PANTHER PTHR10169 28 105 7.5E-25 T 22-04-2016 HRM2_RS24490 18b0e1fd47f4785e99ed572b235ff300 105 Gene3D G3DSA:3.40.50.670 16 102 2.4E-23 T 22-04-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS24490 18b0e1fd47f4785e99ed572b235ff300 105 SUPERFAMILY SSF56719 14 105 3.66E-19 T 22-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 HRM2_RS05250 f99672606b930144df4fa1af5d618b67 825 SUPERFAMILY SSF51735 481 644 8.86E-9 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS05250 f99672606b930144df4fa1af5d618b67 825 Gene3D G3DSA:1.10.1040.10 669 813 1.4E-5 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HRM2_RS05250 f99672606b930144df4fa1af5d618b67 825 SUPERFAMILY SSF69593 309 345 3.4E-8 T 22-04-2016 HRM2_RS05250 f99672606b930144df4fa1af5d618b67 825 SUPERFAMILY SSF69593 135 281 3.4E-8 T 22-04-2016 HRM2_RS05250 f99672606b930144df4fa1af5d618b67 825 SMART SM00563 153 279 2.1E-4 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 HRM2_RS05250 f99672606b930144df4fa1af5d618b67 825 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 483 634 1.0E-10 T 22-04-2016 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 HRM2_RS05250 f99672606b930144df4fa1af5d618b67 825 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 662 686 4.1E-5 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 HRM2_RS05250 f99672606b930144df4fa1af5d618b67 825 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 485 502 4.1E-5 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 HRM2_RS05250 f99672606b930144df4fa1af5d618b67 825 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 543 570 4.1E-5 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 HRM2_RS05250 f99672606b930144df4fa1af5d618b67 825 Gene3D G3DSA:3.40.50.720 478 637 4.4E-14 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS05250 f99672606b930144df4fa1af5d618b67 825 Pfam PF01553 Acyltransferase 145 276 2.6E-7 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 HRM2_RS10805 37d733e7aa8883b9cb994f56457bf380 547 ProSitePatterns PS00455 Putative AMP-binding domain signature. 177 188 - T 22-04-2016 IPR020845 AMP-binding, conserved site HRM2_RS10805 37d733e7aa8883b9cb994f56457bf380 547 PANTHER PTHR24095 384 473 1.1E-67 T 22-04-2016 HRM2_RS10805 37d733e7aa8883b9cb994f56457bf380 547 PANTHER PTHR24095 1 364 1.1E-67 T 22-04-2016 HRM2_RS10805 37d733e7aa8883b9cb994f56457bf380 547 Pfam PF00501 AMP-binding enzyme 12 444 2.5E-56 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS10805 37d733e7aa8883b9cb994f56457bf380 547 SUPERFAMILY SSF56801 6 542 4.32E-82 T 22-04-2016 HRM2_RS10805 37d733e7aa8883b9cb994f56457bf380 547 Gene3D G3DSA:3.40.50.980 183 335 3.4E-25 T 22-04-2016 HRM2_RS10805 37d733e7aa8883b9cb994f56457bf380 547 Gene3D G3DSA:2.30.38.10 352 439 5.6E-13 T 22-04-2016 HRM2_RS10805 37d733e7aa8883b9cb994f56457bf380 547 Gene3D G3DSA:3.40.50.980 7 182 7.7E-27 T 22-04-2016 HRM2_RS10805 37d733e7aa8883b9cb994f56457bf380 547 PANTHER PTHR24095:SF123 384 473 1.1E-67 T 22-04-2016 HRM2_RS10805 37d733e7aa8883b9cb994f56457bf380 547 PANTHER PTHR24095:SF123 1 364 1.1E-67 T 22-04-2016 HRM2_RS06655 2843f00dece1daec674d3b54a723f17e 459 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 129 342 7.4E-61 T 22-04-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS06655 2843f00dece1daec674d3b54a723f17e 459 Gene3D G3DSA:1.10.1140.10 346 455 1.4E-41 T 22-04-2016 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS06655 2843f00dece1daec674d3b54a723f17e 459 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 333 342 - T 22-04-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS06655 2843f00dece1daec674d3b54a723f17e 459 Gene3D G3DSA:2.40.10.170 2 73 8.9E-18 T 22-04-2016 HRM2_RS06655 2843f00dece1daec674d3b54a723f17e 459 Gene3D G3DSA:3.40.50.300 75 342 3.1E-90 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06655 2843f00dece1daec674d3b54a723f17e 459 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 7 70 1.7E-10 T 22-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS06655 2843f00dece1daec674d3b54a723f17e 459 SUPERFAMILY SSF50615 4 73 2.07E-14 T 22-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS06655 2843f00dece1daec674d3b54a723f17e 459 SUPERFAMILY SSF52540 76 347 4.42E-83 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06655 2843f00dece1daec674d3b54a723f17e 459 PANTHER PTHR15184:SF8 1 455 6.2E-236 T 22-04-2016 HRM2_RS06655 2843f00dece1daec674d3b54a723f17e 459 SUPERFAMILY SSF47917 345 456 9.94E-41 T 22-04-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS06655 2843f00dece1daec674d3b54a723f17e 459 Hamap MF_01347 ATP synthase subunit beta [atpB]. 2 459 46.126 T 22-04-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS06655 2843f00dece1daec674d3b54a723f17e 459 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 4 455 1.5E-181 T 22-04-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS06655 2843f00dece1daec674d3b54a723f17e 459 PANTHER PTHR15184 1 455 6.2E-236 T 22-04-2016 HRM2_RS00560 c2d92d06eb642c3dfcdb3106767a1f87 594 Pfam PF00890 FAD binding domain 60 155 1.2E-11 T 22-04-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain HRM2_RS00560 c2d92d06eb642c3dfcdb3106767a1f87 594 PANTHER PTHR11632 388 588 6.4E-19 T 22-04-2016 HRM2_RS00560 c2d92d06eb642c3dfcdb3106767a1f87 594 Gene3D G3DSA:3.50.50.60 56 278 6.5E-42 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS00560 c2d92d06eb642c3dfcdb3106767a1f87 594 Gene3D G3DSA:3.50.50.60 387 452 6.5E-42 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS00560 c2d92d06eb642c3dfcdb3106767a1f87 594 SUPERFAMILY SSF46977 471 590 1.1E-25 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 HRM2_RS00560 c2d92d06eb642c3dfcdb3106767a1f87 594 SUPERFAMILY SSF51905 55 256 5.38E-40 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS00560 c2d92d06eb642c3dfcdb3106767a1f87 594 SUPERFAMILY SSF51905 387 447 5.38E-40 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS00560 c2d92d06eb642c3dfcdb3106767a1f87 594 Gene3D G3DSA:1.20.58.100 453 562 2.0E-27 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 HRM2_RS00560 c2d92d06eb642c3dfcdb3106767a1f87 594 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 386 408 2.6E-11 T 22-04-2016 HRM2_RS00560 c2d92d06eb642c3dfcdb3106767a1f87 594 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 210 228 2.6E-11 T 22-04-2016 HRM2_RS00560 c2d92d06eb642c3dfcdb3106767a1f87 594 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 61 80 2.6E-11 T 22-04-2016 HRM2_RS00560 c2d92d06eb642c3dfcdb3106767a1f87 594 PANTHER PTHR11632:SF6 388 588 6.4E-19 T 22-04-2016 HRM2_RS00560 c2d92d06eb642c3dfcdb3106767a1f87 594 Pfam PF02910 Fumarate reductase flavoprotein C-term 480 589 4.4E-11 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 HRM2_RS00560 c2d92d06eb642c3dfcdb3106767a1f87 594 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 401 408 2.6E-6 T 22-04-2016 HRM2_RS00560 c2d92d06eb642c3dfcdb3106767a1f87 594 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 60 82 2.6E-6 T 22-04-2016 HRM2_RS02490 5c32a92947c26e3b0ae6884b6a9049fa 262 Pfam PF03309 Type III pantothenate kinase 2 208 2.5E-67 T 22-04-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 HRM2_RS02490 5c32a92947c26e3b0ae6884b6a9049fa 262 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 256 34.608 T 22-04-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 HRM2_RS02490 5c32a92947c26e3b0ae6884b6a9049fa 262 Gene3D G3DSA:3.30.420.40 98 254 3.0E-49 T 22-04-2016 HRM2_RS02490 5c32a92947c26e3b0ae6884b6a9049fa 262 SUPERFAMILY SSF53067 1 122 7.77E-33 T 22-04-2016 HRM2_RS02490 5c32a92947c26e3b0ae6884b6a9049fa 262 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 252 1.1E-69 T 22-04-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 HRM2_RS02490 5c32a92947c26e3b0ae6884b6a9049fa 262 SUPERFAMILY SSF53067 125 253 6.62E-37 T 22-04-2016 HRM2_RS02490 5c32a92947c26e3b0ae6884b6a9049fa 262 PANTHER PTHR34265 1 252 1.3E-67 T 22-04-2016 HRM2_RS25455 ddc3d0b8a6db3ccbbdfff23c3ed82285 665 PANTHER PTHR23150 438 662 2.3E-56 T 22-04-2016 HRM2_RS25455 ddc3d0b8a6db3ccbbdfff23c3ed82285 665 Gene3D G3DSA:3.40.50.300 30 112 1.4E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS25455 ddc3d0b8a6db3ccbbdfff23c3ed82285 665 Gene3D G3DSA:3.90.1580.10 438 662 2.6E-55 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme HRM2_RS25455 ddc3d0b8a6db3ccbbdfff23c3ed82285 665 SUPERFAMILY SSF52540 197 316 1.46E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS25455 ddc3d0b8a6db3ccbbdfff23c3ed82285 665 SUPERFAMILY SSF52540 24 158 1.46E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS25455 ddc3d0b8a6db3ccbbdfff23c3ed82285 665 SUPERFAMILY SSF56436 442 662 4.94E-60 T 22-04-2016 IPR016187 C-type lectin fold HRM2_RS25455 ddc3d0b8a6db3ccbbdfff23c3ed82285 665 Pfam PF07693 KAP family P-loop domain 192 318 6.2E-21 T 22-04-2016 IPR011646 KAP family P-loop domain HRM2_RS25455 ddc3d0b8a6db3ccbbdfff23c3ed82285 665 Pfam PF07693 KAP family P-loop domain 23 110 4.2E-15 T 22-04-2016 IPR011646 KAP family P-loop domain HRM2_RS25455 ddc3d0b8a6db3ccbbdfff23c3ed82285 665 Pfam PF03781 Sulfatase-modifying factor enzyme 1 442 662 9.2E-48 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme HRM2_RS25455 ddc3d0b8a6db3ccbbdfff23c3ed82285 665 Gene3D G3DSA:3.40.50.300 138 236 5.4E-5 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS25455 ddc3d0b8a6db3ccbbdfff23c3ed82285 665 PANTHER PTHR23150:SF19 438 662 2.3E-56 T 22-04-2016 HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 694 51.934 T 22-04-2016 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 PANTHER PTHR11390 1 748 0.0 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 Pfam PF01131 DNA topoisomerase 128 547 1.1E-120 T 22-04-2016 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 632 666 4.4E-13 T 22-04-2016 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 678 715 7.1E-11 T 22-04-2016 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 578 610 1.5E-11 T 22-04-2016 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 721 755 0.0013 T 22-04-2016 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 Gene3D G3DSA:2.70.20.10 318 456 5.6E-32 T 22-04-2016 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 Gene3D G3DSA:2.70.20.10 184 315 7.1E-28 T 22-04-2016 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 Gene3D G3DSA:3.40.50.140 2 132 8.9E-39 T 22-04-2016 IPR006171 Toprim domain HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 SUPERFAMILY SSF56712 3 588 1.96E-182 T 22-04-2016 IPR023405 DNA topoisomerase, type IA, core domain HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 SUPERFAMILY SSF57783 624 666 2.38E-11 T 22-04-2016 HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 Gene3D G3DSA:1.10.460.10 719 725 8.4E-53 T 22-04-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 Gene3D G3DSA:1.10.460.10 457 561 8.4E-53 T 22-04-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 Gene3D G3DSA:1.10.460.10 135 182 8.4E-53 T 22-04-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 SMART SM00493 3 103 3.6E-29 T 22-04-2016 IPR006171 Toprim domain HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 SUPERFAMILY SSF57783 576 615 1.48E-9 T 22-04-2016 HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 Pfam PF01751 Toprim domain 5 113 2.5E-26 T 22-04-2016 IPR006171 Toprim domain HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 SMART SM00436 104 192 2.3E-44 T 22-04-2016 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 371 387 1.4E-35 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 162 180 1.4E-35 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 294 303 1.4E-35 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 473 487 1.4E-35 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 1.4E-35 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 610 2.0E-229 T 22-04-2016 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 Gene3D G3DSA:3.30.65.10 624 666 6.2E-16 T 22-04-2016 HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 Gene3D G3DSA:3.30.65.10 575 609 1.1E-11 T 22-04-2016 HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 280 303 - T 22-04-2016 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 PANTHER PTHR11390:SF27 1 748 0.0 T 22-04-2016 HRM2_RS13505 e579f0682bd0f05ad9b370dfb78d0d34 756 SMART SM00437 243 510 2.9E-107 T 22-04-2016 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 HRM2_RS25025 67dd71d15bf919a3135a90feef1530d6 763 Gene3D G3DSA:3.30.565.10 445 625 9.4E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25025 67dd71d15bf919a3135a90feef1530d6 763 SMART SM00448 642 755 4.9E-20 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS25025 67dd71d15bf919a3135a90feef1530d6 763 PANTHER PTHR24423 377 762 1.6E-122 T 22-04-2016 HRM2_RS25025 67dd71d15bf919a3135a90feef1530d6 763 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 501 622 7.5E-22 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25025 67dd71d15bf919a3135a90feef1530d6 763 SUPERFAMILY SSF47384 384 456 4.32E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25025 67dd71d15bf919a3135a90feef1530d6 763 SMART SM00388 393 459 3.7E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25025 67dd71d15bf919a3135a90feef1530d6 763 SUPERFAMILY SSF52172 643 760 1.71E-27 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS25025 67dd71d15bf919a3135a90feef1530d6 763 Gene3D G3DSA:3.40.50.2300 641 762 3.0E-28 T 22-04-2016 HRM2_RS25025 67dd71d15bf919a3135a90feef1530d6 763 SMART SM00387 500 624 5.3E-27 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25025 67dd71d15bf919a3135a90feef1530d6 763 Pfam PF00512 His Kinase A (phospho-acceptor) domain 393 457 3.8E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25025 67dd71d15bf919a3135a90feef1530d6 763 Pfam PF00072 Response regulator receiver domain 644 753 2.0E-18 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS25025 67dd71d15bf919a3135a90feef1530d6 763 Gene3D G3DSA:1.10.287.130 389 444 9.1E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25025 67dd71d15bf919a3135a90feef1530d6 763 SUPERFAMILY SSF55874 449 623 4.19E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25025 67dd71d15bf919a3135a90feef1530d6 763 PRINTS PR00344 Bacterial sensor protein C-terminal signature 608 621 7.1E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25025 67dd71d15bf919a3135a90feef1530d6 763 PRINTS PR00344 Bacterial sensor protein C-terminal signature 553 567 7.1E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25025 67dd71d15bf919a3135a90feef1530d6 763 PRINTS PR00344 Bacterial sensor protein C-terminal signature 584 602 7.1E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25025 67dd71d15bf919a3135a90feef1530d6 763 PRINTS PR00344 Bacterial sensor protein C-terminal signature 571 581 7.1E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25025 67dd71d15bf919a3135a90feef1530d6 763 PANTHER PTHR24423:SF544 377 762 1.6E-122 T 22-04-2016 HRM2_RS25025 67dd71d15bf919a3135a90feef1530d6 763 Gene3D G3DSA:3.30.450.20 175 323 2.7E-10 T 22-04-2016 HRM2_RS05530 099fc1aa5110034c0ae292bcd43dfa6c 518 SMART SM00382 213 396 7.9E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS05530 099fc1aa5110034c0ae292bcd43dfa6c 518 SUPERFAMILY SSF52540 190 506 1.5E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05530 099fc1aa5110034c0ae292bcd43dfa6c 518 Gene3D G3DSA:3.30.230.10 5 167 4.1E-40 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HRM2_RS05530 099fc1aa5110034c0ae292bcd43dfa6c 518 Pfam PF13541 Subunit ChlI of Mg-chelatase 20 142 1.3E-45 T 22-04-2016 HRM2_RS05530 099fc1aa5110034c0ae292bcd43dfa6c 518 Pfam PF01078 Magnesium chelatase, subunit ChlI 193 399 1.8E-95 T 22-04-2016 IPR000523 Magnesium chelatase ChlI domain HRM2_RS05530 099fc1aa5110034c0ae292bcd43dfa6c 518 SUPERFAMILY SSF54211 10 169 2.66E-40 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS05530 099fc1aa5110034c0ae292bcd43dfa6c 518 PANTHER PTHR32039:SF7 2 506 1.7E-252 T 22-04-2016 IPR004482 Mg chelatase-related protein HRM2_RS05530 099fc1aa5110034c0ae292bcd43dfa6c 518 PANTHER PTHR32039 2 506 1.7E-252 T 22-04-2016 HRM2_RS05530 099fc1aa5110034c0ae292bcd43dfa6c 518 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 407 502 1.2E-27 T 22-04-2016 IPR025158 Mg chelatase-related protein, C-terminal domain HRM2_RS05530 099fc1aa5110034c0ae292bcd43dfa6c 518 Gene3D G3DSA:3.40.50.300 191 392 2.1E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05530 099fc1aa5110034c0ae292bcd43dfa6c 518 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 6 502 4.9E-190 T 22-04-2016 IPR004482 Mg chelatase-related protein HRM2_RS05530 099fc1aa5110034c0ae292bcd43dfa6c 518 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 345 357 3.5E-6 T 22-04-2016 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 HRM2_RS05530 099fc1aa5110034c0ae292bcd43dfa6c 518 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 321 334 3.5E-6 T 22-04-2016 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 HRM2_RS05530 099fc1aa5110034c0ae292bcd43dfa6c 518 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 212 227 3.5E-6 T 22-04-2016 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 HRM2_RS05530 099fc1aa5110034c0ae292bcd43dfa6c 518 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 293 307 3.5E-6 T 22-04-2016 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 HRM2_RS05420 7573af414dad4a233038f54d1c257234 473 SMART SM00387 365 471 4.4E-27 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS05420 7573af414dad4a233038f54d1c257234 473 Pfam PF00512 His Kinase A (phospho-acceptor) domain 259 320 4.8E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS05420 7573af414dad4a233038f54d1c257234 473 SUPERFAMILY SSF55874 313 469 1.83E-37 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS05420 7573af414dad4a233038f54d1c257234 473 SUPERFAMILY SSF47384 250 323 4.51E-15 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS05420 7573af414dad4a233038f54d1c257234 473 PANTHER PTHR24423 161 196 2.1E-62 T 22-04-2016 HRM2_RS05420 7573af414dad4a233038f54d1c257234 473 PANTHER PTHR24423 241 472 2.1E-62 T 22-04-2016 HRM2_RS05420 7573af414dad4a233038f54d1c257234 473 PANTHER PTHR24423 3 13 2.1E-62 T 22-04-2016 HRM2_RS05420 7573af414dad4a233038f54d1c257234 473 SMART SM00388 257 323 3.9E-16 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS05420 7573af414dad4a233038f54d1c257234 473 Gene3D G3DSA:1.10.287.130 251 308 1.1E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS05420 7573af414dad4a233038f54d1c257234 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 455 468 2.3E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS05420 7573af414dad4a233038f54d1c257234 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 430 2.3E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS05420 7573af414dad4a233038f54d1c257234 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 449 2.3E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS05420 7573af414dad4a233038f54d1c257234 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 416 2.3E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS05420 7573af414dad4a233038f54d1c257234 473 Gene3D G3DSA:3.30.565.10 309 471 6.7E-37 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS05420 7573af414dad4a233038f54d1c257234 473 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 366 469 2.5E-15 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS16365 33394e515a4e42863b283bbe535b2e0c 368 PANTHER PTHR22976 4 363 1.2E-137 T 22-04-2016 HRM2_RS16365 33394e515a4e42863b283bbe535b2e0c 368 PIRSF PIRSF004762 1 366 7.9E-118 T 22-04-2016 IPR005244 FO synthase, subunit 2-like GO:0016765|GO:0051188|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198|UniPathway: UPA00072 HRM2_RS16365 33394e515a4e42863b283bbe535b2e0c 368 SUPERFAMILY SSF102114 21 354 1.27E-49 T 22-04-2016 HRM2_RS16365 33394e515a4e42863b283bbe535b2e0c 368 Gene3D G3DSA:3.20.20.70 22 353 1.0E-59 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS16365 33394e515a4e42863b283bbe535b2e0c 368 Hamap MF_00993 Aminodeoxyfutalosine synthase [mqnE]. 10 364 51.885 T 22-04-2016 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374|UniPathway: UPA00079 HRM2_RS16365 33394e515a4e42863b283bbe535b2e0c 368 PANTHER PTHR22976:SF4 4 363 1.2E-137 T 22-04-2016 HRM2_RS16365 33394e515a4e42863b283bbe535b2e0c 368 TIGRFAM TIGR03700 mena_SCO4494: putative menaquinone biosynthesis radical SAM enzyme, SCO4494 family 14 361 4.3E-146 T 22-04-2016 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374|UniPathway: UPA00079 HRM2_RS16365 33394e515a4e42863b283bbe535b2e0c 368 SMART SM00729 57 277 2.1E-4 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS16365 33394e515a4e42863b283bbe535b2e0c 368 Pfam PF04055 Radical SAM superfamily 66 235 2.3E-10 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS16365 33394e515a4e42863b283bbe535b2e0c 368 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 57 359 3.2E-111 T 22-04-2016 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198|UniPathway: UPA00072 HRM2_RS12555 1c481b8d5cc603560bc8e6ce58aec08a 479 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 346 352 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HRM2_RS12555 1c481b8d5cc603560bc8e6ce58aec08a 479 SUPERFAMILY SSF53335 339 411 1.23E-7 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS12555 1c481b8d5cc603560bc8e6ce58aec08a 479 Gene3D G3DSA:1.10.260.40 128 154 2.8E-4 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS12555 1c481b8d5cc603560bc8e6ce58aec08a 479 Gene3D G3DSA:3.40.50.150 232 317 8.3E-9 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS12555 1c481b8d5cc603560bc8e6ce58aec08a 479 Gene3D G3DSA:3.40.50.150 341 438 1.3E-5 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS12555 1c481b8d5cc603560bc8e6ce58aec08a 479 SUPERFAMILY SSF110849 14 85 9.07E-5 T 22-04-2016 IPR003115 ParB/Sulfiredoxin HRM2_RS12555 1c481b8d5cc603560bc8e6ce58aec08a 479 SUPERFAMILY SSF53335 210 316 9.7E-11 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS18415 348abe98e01c4183571a9ca6aac7fbaa 136 PIRSF PIRSF002889 2 134 8.1E-25 T 22-04-2016 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 HRM2_RS18415 348abe98e01c4183571a9ca6aac7fbaa 136 PANTHER PTHR30435:SF12 4 132 2.7E-22 T 22-04-2016 HRM2_RS18415 348abe98e01c4183571a9ca6aac7fbaa 136 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 7 132 2.2E-24 T 22-04-2016 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 HRM2_RS18415 348abe98e01c4183571a9ca6aac7fbaa 136 PANTHER PTHR30435 4 132 2.7E-22 T 22-04-2016 HRM2_RS12270 60897be7924f22bcd035ef0f36a34d08 158 SMART SM00271 95 158 3.5E-10 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS12270 60897be7924f22bcd035ef0f36a34d08 158 Pfam PF00226 DnaJ domain 97 153 3.2E-12 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS12270 60897be7924f22bcd035ef0f36a34d08 158 SUPERFAMILY SSF46565 53 153 4.97E-17 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS12270 60897be7924f22bcd035ef0f36a34d08 158 PRINTS PR00625 DnaJ domain signature 138 158 1.6E-8 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS12270 60897be7924f22bcd035ef0f36a34d08 158 PRINTS PR00625 DnaJ domain signature 98 116 1.6E-8 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS12270 60897be7924f22bcd035ef0f36a34d08 158 PRINTS PR00625 DnaJ domain signature 116 131 1.6E-8 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS12270 60897be7924f22bcd035ef0f36a34d08 158 Pfam PF06803 Protein of unknown function (DUF1232) 7 43 2.3E-12 T 22-04-2016 IPR010652 Protein of unknown function DUF1232 UniPathway: UPA00143 HRM2_RS12270 60897be7924f22bcd035ef0f36a34d08 158 Gene3D G3DSA:1.10.287.110 94 153 5.0E-14 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS20870 47536406bf79fbba59b80fdde20e7b98 150 Pfam PF02085 Class III cytochrome C family 34 147 4.3E-13 T 22-04-2016 IPR020942 Class III cytochrome C GO:0009055|GO:0020037 HRM2_RS20870 47536406bf79fbba59b80fdde20e7b98 150 Gene3D G3DSA:3.90.10.10 33 149 2.8E-15 T 22-04-2016 HRM2_RS20870 47536406bf79fbba59b80fdde20e7b98 150 SUPERFAMILY SSF48695 38 147 2.33E-13 T 22-04-2016 IPR011031 Multihaem cytochrome HRM2_RS20870 47536406bf79fbba59b80fdde20e7b98 150 PRINTS PR00609 Class III cytochrome C signature 57 64 3.7E-7 T 22-04-2016 IPR002322 Cytochrome c, class III GO:0009055|GO:0020037 HRM2_RS20870 47536406bf79fbba59b80fdde20e7b98 150 PRINTS PR00609 Class III cytochrome C signature 80 91 3.7E-7 T 22-04-2016 IPR002322 Cytochrome c, class III GO:0009055|GO:0020037 HRM2_RS20870 47536406bf79fbba59b80fdde20e7b98 150 PRINTS PR00609 Class III cytochrome C signature 140 147 3.7E-7 T 22-04-2016 IPR002322 Cytochrome c, class III GO:0009055|GO:0020037 HRM2_RS20870 47536406bf79fbba59b80fdde20e7b98 150 PRINTS PR00609 Class III cytochrome C signature 43 52 3.7E-7 T 22-04-2016 IPR002322 Cytochrome c, class III GO:0009055|GO:0020037 HRM2_RS18920 7d534ad9752370e3a92b5ad53427e01f 171 PANTHER PTHR31964 4 171 5.0E-15 T 22-04-2016 HRM2_RS18920 7d534ad9752370e3a92b5ad53427e01f 171 Pfam PF00582 Universal stress protein family 5 164 2.9E-21 T 22-04-2016 IPR006016 UspA GO:0006950 HRM2_RS18920 7d534ad9752370e3a92b5ad53427e01f 171 PANTHER PTHR31964:SF45 4 171 5.0E-15 T 22-04-2016 HRM2_RS18920 7d534ad9752370e3a92b5ad53427e01f 171 PRINTS PR01438 Universal stress protein signature 5 23 4.2E-7 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS18920 7d534ad9752370e3a92b5ad53427e01f 171 PRINTS PR01438 Universal stress protein signature 145 167 4.2E-7 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS18920 7d534ad9752370e3a92b5ad53427e01f 171 PRINTS PR01438 Universal stress protein signature 127 139 4.2E-7 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS18920 7d534ad9752370e3a92b5ad53427e01f 171 Gene3D G3DSA:3.40.50.620 3 167 2.6E-42 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS18920 7d534ad9752370e3a92b5ad53427e01f 171 SUPERFAMILY SSF52402 4 168 1.33E-22 T 22-04-2016 HRM2_RS10920 62c2a877ec9951cc5885668d13f61e2a 281 SUPERFAMILY SSF63380 3 108 3.76E-19 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 HRM2_RS10920 62c2a877ec9951cc5885668d13f61e2a 281 Gene3D G3DSA:2.10.240.10 242 274 2.4E-13 T 22-04-2016 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain UniPathway: UPA00070 HRM2_RS10920 62c2a877ec9951cc5885668d13f61e2a 281 PANTHER PTHR19370 3 264 9.6E-47 T 22-04-2016 HRM2_RS10920 62c2a877ec9951cc5885668d13f61e2a 281 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 242 274 8.7E-11 T 22-04-2016 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain UniPathway: UPA00070 HRM2_RS10920 62c2a877ec9951cc5885668d13f61e2a 281 SUPERFAMILY SSF52343 100 274 5.76E-27 T 22-04-2016 HRM2_RS10920 62c2a877ec9951cc5885668d13f61e2a 281 PANTHER PTHR19370:SF70 3 264 9.6E-47 T 22-04-2016 HRM2_RS10920 62c2a877ec9951cc5885668d13f61e2a 281 Gene3D G3DSA:3.40.50.80 95 238 9.0E-28 T 22-04-2016 HRM2_RS10920 62c2a877ec9951cc5885668d13f61e2a 281 Pfam PF00970 Oxidoreductase FAD-binding domain 21 104 1.7E-7 T 22-04-2016 IPR008333 Oxidoreductase, FAD-binding domain HRM2_RS10920 62c2a877ec9951cc5885668d13f61e2a 281 Pfam PF00175 Oxidoreductase NAD-binding domain 118 224 3.7E-13 T 22-04-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 HRM2_RS10920 62c2a877ec9951cc5885668d13f61e2a 281 Gene3D G3DSA:2.40.30.10 3 94 1.4E-16 T 22-04-2016 HRM2_RS10920 62c2a877ec9951cc5885668d13f61e2a 281 PIRSF PIRSF006816 4 279 4.5E-64 T 22-04-2016 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 UniPathway: UPA00070 HRM2_RS10920 62c2a877ec9951cc5885668d13f61e2a 281 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 144 153 1.4E-5 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 HRM2_RS10920 62c2a877ec9951cc5885668d13f61e2a 281 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 210 218 1.4E-5 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 HRM2_RS10920 62c2a877ec9951cc5885668d13f61e2a 281 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 116 135 1.4E-5 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 HRM2_RS10920 62c2a877ec9951cc5885668d13f61e2a 281 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 156 167 1.4E-5 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 HRM2_RS10920 62c2a877ec9951cc5885668d13f61e2a 281 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 80 89 1.4E-5 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 HRM2_RS15735 5db99c7a089bb8f9003fbe94b802de7b 252 Pfam PF13614 AAA domain 3 178 2.9E-68 T 22-04-2016 IPR025669 AAA domain HRM2_RS15735 5db99c7a089bb8f9003fbe94b802de7b 252 SUPERFAMILY SSF52540 1 251 1.16E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS15735 5db99c7a089bb8f9003fbe94b802de7b 252 PANTHER PTHR13696:SF52 1 252 2.3E-91 T 22-04-2016 HRM2_RS15735 5db99c7a089bb8f9003fbe94b802de7b 252 PRINTS PR00091 Nitrogenase component II signature 9 22 4.5E-6 T 22-04-2016 IPR000392 Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL GO:0005524|GO:0016491|GO:0055114 HRM2_RS15735 5db99c7a089bb8f9003fbe94b802de7b 252 PRINTS PR00091 Nitrogenase component II signature 31 46 4.5E-6 T 22-04-2016 IPR000392 Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL GO:0005524|GO:0016491|GO:0055114 HRM2_RS15735 5db99c7a089bb8f9003fbe94b802de7b 252 Gene3D G3DSA:3.40.50.300 4 252 7.0E-73 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS15735 5db99c7a089bb8f9003fbe94b802de7b 252 PANTHER PTHR13696 1 252 2.3E-91 T 22-04-2016 HRM2_RS09200 5418e936edf8bd8439d15d55ec54ce20 190 SUPERFAMILY SSF52540 6 187 5.05E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09200 5418e936edf8bd8439d15d55ec54ce20 190 PANTHER PTHR23117:SF13 8 188 1.7E-81 T 22-04-2016 HRM2_RS09200 5418e936edf8bd8439d15d55ec54ce20 190 Hamap MF_00328 Guanylate kinase [gmk]. 6 189 33.862 T 22-04-2016 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 HRM2_RS09200 5418e936edf8bd8439d15d55ec54ce20 190 Gene3D G3DSA:3.40.50.300 3 48 7.0E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09200 5418e936edf8bd8439d15d55ec54ce20 190 SMART SM00072 7 189 1.6E-58 T 22-04-2016 IPR008145 Guanylate kinase/L-type calcium channel beta subunit HRM2_RS09200 5418e936edf8bd8439d15d55ec54ce20 190 Gene3D G3DSA:3.30.63.10 49 89 2.2E-25 T 22-04-2016 HRM2_RS09200 5418e936edf8bd8439d15d55ec54ce20 190 Gene3D G3DSA:3.40.50.300 90 188 7.4E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09200 5418e936edf8bd8439d15d55ec54ce20 190 PANTHER PTHR23117 8 188 1.7E-81 T 22-04-2016 HRM2_RS09200 5418e936edf8bd8439d15d55ec54ce20 190 Pfam PF00625 Guanylate kinase 9 187 2.3E-48 T 22-04-2016 IPR008145 Guanylate kinase/L-type calcium channel beta subunit HRM2_RS09200 5418e936edf8bd8439d15d55ec54ce20 190 ProSitePatterns PS00856 Guanylate kinase-like signature. 42 59 - T 22-04-2016 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 HRM2_RS09200 5418e936edf8bd8439d15d55ec54ce20 190 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 8 186 7.1E-68 T 22-04-2016 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 HRM2_RS19395 5112c9fc8d18ce5a35fc51dce7e13f8e 173 SUPERFAMILY SSF48452 9 155 4.05E-18 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS19395 5112c9fc8d18ce5a35fc51dce7e13f8e 173 Gene3D G3DSA:1.25.40.10 10 156 1.7E-19 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS19395 5112c9fc8d18ce5a35fc51dce7e13f8e 173 SMART SM00028 83 116 9.5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS19395 5112c9fc8d18ce5a35fc51dce7e13f8e 173 SMART SM00028 49 82 0.26 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS19395 5112c9fc8d18ce5a35fc51dce7e13f8e 173 SMART SM00028 122 155 200.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS19395 5112c9fc8d18ce5a35fc51dce7e13f8e 173 Pfam PF13181 Tetratricopeptide repeat 85 112 0.16 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS19395 5112c9fc8d18ce5a35fc51dce7e13f8e 173 PANTHER PTHR23083 7 156 6.0E-14 T 22-04-2016 HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 SUPERFAMILY SSF47384 714 795 5.69E-22 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 Pfam PF13185 GAF domain 401 537 2.8E-18 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 Gene3D G3DSA:1.10.287.130 733 780 8.8E-17 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 SUPERFAMILY SSF103190 52 219 1.49E-45 T 22-04-2016 IPR029151 Periplasmic sensor domain-like HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 Pfam PF00512 His Kinase A (phospho-acceptor) domain 727 795 5.7E-20 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 SMART SM00091 592 658 1.7E-9 T 22-04-2016 IPR000014 PAS domain HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 SMART SM00065 402 549 5.1E-18 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 Pfam PF08447 PAS fold 615 701 2.8E-12 T 22-04-2016 IPR013655 PAS fold-3 GO:0005515 HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 589 714 1.0E-29 T 22-04-2016 IPR000014 PAS domain HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 Gene3D G3DSA:3.30.450.20 590 732 1.9E-30 T 22-04-2016 HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 SMART SM00086 665 707 2.3E-9 T 22-04-2016 IPR001610 PAC motif HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 Gene3D G3DSA:3.30.450.20 230 339 2.2E-27 T 22-04-2016 HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 PANTHER PTHR24423 18 27 5.0E-111 T 22-04-2016 HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 PANTHER PTHR24423 576 874 5.0E-111 T 22-04-2016 HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 PANTHER PTHR24423 896 995 5.0E-111 T 22-04-2016 HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 SUPERFAMILY SSF55785 578 705 9.34E-26 T 22-04-2016 IPR000014 PAS domain HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 SUPERFAMILY SSF55874 784 878 8.92E-40 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 SUPERFAMILY SSF55874 906 984 8.92E-40 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 SMART SM00387 843 983 3.7E-33 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 Gene3D G3DSA:3.30.450.40 390 548 2.2E-32 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 844 982 1.6E-20 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 Gene3D G3DSA:3.30.450.20 87 220 1.0E-40 T 22-04-2016 HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 SMART SM00388 727 795 2.8E-25 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 Gene3D G3DSA:3.30.565.10 781 983 8.2E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 SUPERFAMILY SSF103190 231 337 1.33E-23 T 22-04-2016 IPR029151 Periplasmic sensor domain-like HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 PRINTS PR00344 Bacterial sensor protein C-terminal signature 967 980 5.3E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 PRINTS PR00344 Bacterial sensor protein C-terminal signature 907 921 5.3E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 PRINTS PR00344 Bacterial sensor protein C-terminal signature 942 960 5.3E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 PRINTS PR00344 Bacterial sensor protein C-terminal signature 925 935 5.3E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25435 4e5bce120bd3e7f4ca3b4907d5f051c4 1003 SUPERFAMILY SSF55781 389 556 4.14E-30 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS01085 6360cf9454e6b30fcd5ee005fb2deb9a 500 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 7 484 1.9E-130 T 22-04-2016 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 UniPathway: UPA00148 HRM2_RS01085 6360cf9454e6b30fcd5ee005fb2deb9a 500 SUPERFAMILY SSF52540 6 239 1.79E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01085 6360cf9454e6b30fcd5ee005fb2deb9a 500 Gene3D G3DSA:3.40.50.880 256 452 2.4E-27 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS01085 6360cf9454e6b30fcd5ee005fb2deb9a 500 PANTHER PTHR21343 1 490 3.2E-188 T 22-04-2016 HRM2_RS01085 6360cf9454e6b30fcd5ee005fb2deb9a 500 Gene3D G3DSA:3.40.50.300 6 239 6.5E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01085 6360cf9454e6b30fcd5ee005fb2deb9a 500 SUPERFAMILY SSF52317 269 409 6.8E-34 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS01085 6360cf9454e6b30fcd5ee005fb2deb9a 500 SUPERFAMILY SSF52317 191 240 6.8E-34 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS01085 6360cf9454e6b30fcd5ee005fb2deb9a 500 PANTHER PTHR21343:SF1 1 490 3.2E-188 T 22-04-2016 HRM2_RS01085 6360cf9454e6b30fcd5ee005fb2deb9a 500 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 7 234 5.6E-26 T 22-04-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain HRM2_RS01085 6360cf9454e6b30fcd5ee005fb2deb9a 500 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 258 442 1.4E-50 T 22-04-2016 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 UniPathway: UPA00148 HRM2_RS01085 6360cf9454e6b30fcd5ee005fb2deb9a 500 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 493 164.144 T 22-04-2016 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 UniPathway: UPA00148 HRM2_RS25100 00d7bb6e6ae9a2ebddd7d6e71fe55535 215 SUPERFAMILY SSF52540 14 215 1.22E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS25100 00d7bb6e6ae9a2ebddd7d6e71fe55535 215 Gene3D G3DSA:3.40.50.300 8 215 1.6E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS25100 00d7bb6e6ae9a2ebddd7d6e71fe55535 215 SMART SM00382 31 215 1.1E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS25100 00d7bb6e6ae9a2ebddd7d6e71fe55535 215 PANTHER PTHR24220:SF470 8 215 9.5E-58 T 22-04-2016 HRM2_RS25100 00d7bb6e6ae9a2ebddd7d6e71fe55535 215 Pfam PF00005 ABC transporter 26 166 5.1E-30 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS25100 00d7bb6e6ae9a2ebddd7d6e71fe55535 215 PANTHER PTHR24220 8 215 9.5E-58 T 22-04-2016 HRM2_RS22880 79386a69f3699aa635220d0eff50b912 184 PIRSF PIRSF011484 1 180 6.3E-70 T 22-04-2016 IPR009822 YaeQ HRM2_RS22880 79386a69f3699aa635220d0eff50b912 184 PANTHER PTHR38784:SF1 2 181 1.6E-58 T 22-04-2016 HRM2_RS22880 79386a69f3699aa635220d0eff50b912 184 Gene3D G3DSA:3.10.640.10 2 178 1.7E-69 T 22-04-2016 HRM2_RS22880 79386a69f3699aa635220d0eff50b912 184 Pfam PF07152 YaeQ protein 2 172 5.0E-69 T 22-04-2016 IPR009822 YaeQ HRM2_RS22880 79386a69f3699aa635220d0eff50b912 184 SMART SM01322 2 175 3.4E-103 T 22-04-2016 IPR009822 YaeQ HRM2_RS22880 79386a69f3699aa635220d0eff50b912 184 SUPERFAMILY SSF52980 2 177 2.09E-66 T 22-04-2016 IPR011335 Restriction endonuclease type II-like HRM2_RS22880 79386a69f3699aa635220d0eff50b912 184 PANTHER PTHR38784 2 181 1.6E-58 T 22-04-2016 HRM2_RS22675 9fb5a131f3e6a27f8392b2c13b3e1909 289 PANTHER PTHR11048:SF7 7 288 1.6E-59 T 22-04-2016 HRM2_RS22675 9fb5a131f3e6a27f8392b2c13b3e1909 289 TIGRFAM TIGR01475 ubiA_other: putative 4-hydroxybenzoate polyprenyltransferase 10 287 3.5E-83 T 22-04-2016 IPR006371 4-hydroxybenzoate polyprenyltransferase-related HRM2_RS22675 9fb5a131f3e6a27f8392b2c13b3e1909 289 PANTHER PTHR11048 7 288 1.6E-59 T 22-04-2016 HRM2_RS22675 9fb5a131f3e6a27f8392b2c13b3e1909 289 Pfam PF01040 UbiA prenyltransferase family 25 272 1.5E-48 T 22-04-2016 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 HRM2_RS19930 c73af942b434a3dcb78506524e20e636 222 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS19930 c73af942b434a3dcb78506524e20e636 222 Pfam PF00005 ABC transporter 31 175 1.5E-22 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS19930 c73af942b434a3dcb78506524e20e636 222 PANTHER PTHR24220 15 202 3.7E-33 T 22-04-2016 HRM2_RS19930 c73af942b434a3dcb78506524e20e636 222 SUPERFAMILY SSF52540 12 205 2.61E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19930 c73af942b434a3dcb78506524e20e636 222 SMART SM00382 38 222 5.6E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS19930 c73af942b434a3dcb78506524e20e636 222 Gene3D G3DSA:3.40.50.300 10 202 6.4E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10360 bdb3a0fe36a223a228179429d9206a66 330 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 1 328 1.4E-99 T 22-04-2016 IPR011852 TRAP transporter solute receptor, TAXI family HRM2_RS10360 bdb3a0fe36a223a228179429d9206a66 330 Gene3D G3DSA:3.40.190.10 124 260 1.1E-29 T 22-04-2016 HRM2_RS10360 bdb3a0fe36a223a228179429d9206a66 330 Gene3D G3DSA:3.40.190.10 261 329 2.8E-60 T 22-04-2016 HRM2_RS10360 bdb3a0fe36a223a228179429d9206a66 330 Gene3D G3DSA:3.40.190.10 31 113 2.8E-60 T 22-04-2016 HRM2_RS10360 bdb3a0fe36a223a228179429d9206a66 330 PANTHER PTHR30024 1 329 1.4E-79 T 22-04-2016 HRM2_RS10360 bdb3a0fe36a223a228179429d9206a66 330 Pfam PF16868 NMT1-like family 35 328 1.7E-84 T 22-04-2016 IPR011852 TRAP transporter solute receptor, TAXI family HRM2_RS10360 bdb3a0fe36a223a228179429d9206a66 330 SUPERFAMILY SSF53850 31 329 2.12E-74 T 22-04-2016 HRM2_RS10360 bdb3a0fe36a223a228179429d9206a66 330 PANTHER PTHR30024:SF13 1 329 1.4E-79 T 22-04-2016 HRM2_RS09320 f2a352e1bfd05772a5b8fae483253cdf 477 PANTHER PTHR22939 87 390 4.6E-119 T 22-04-2016 HRM2_RS09320 f2a352e1bfd05772a5b8fae483253cdf 477 PANTHER PTHR22939 34 62 4.6E-119 T 22-04-2016 HRM2_RS09320 f2a352e1bfd05772a5b8fae483253cdf 477 SUPERFAMILY SSF50156 385 469 1.26E-13 T 22-04-2016 IPR001478 PDZ domain GO:0005515 HRM2_RS09320 f2a352e1bfd05772a5b8fae483253cdf 477 PANTHER PTHR22939:SF79 87 390 4.6E-119 T 22-04-2016 HRM2_RS09320 f2a352e1bfd05772a5b8fae483253cdf 477 PANTHER PTHR22939:SF79 34 62 4.6E-119 T 22-04-2016 HRM2_RS09320 f2a352e1bfd05772a5b8fae483253cdf 477 Gene3D G3DSA:2.40.10.10 39 166 1.5E-38 T 22-04-2016 HRM2_RS09320 f2a352e1bfd05772a5b8fae483253cdf 477 Pfam PF13180 PDZ domain 406 466 7.2E-8 T 22-04-2016 IPR001478 PDZ domain GO:0005515 HRM2_RS09320 f2a352e1bfd05772a5b8fae483253cdf 477 Pfam PF13180 PDZ domain 274 363 8.3E-18 T 22-04-2016 IPR001478 PDZ domain GO:0005515 HRM2_RS09320 f2a352e1bfd05772a5b8fae483253cdf 477 PRINTS PR00834 HtrA/DegQ protease family signature 209 226 2.3E-54 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HRM2_RS09320 f2a352e1bfd05772a5b8fae483253cdf 477 PRINTS PR00834 HtrA/DegQ protease family signature 175 199 2.3E-54 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HRM2_RS09320 f2a352e1bfd05772a5b8fae483253cdf 477 PRINTS PR00834 HtrA/DegQ protease family signature 114 126 2.3E-54 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HRM2_RS09320 f2a352e1bfd05772a5b8fae483253cdf 477 PRINTS PR00834 HtrA/DegQ protease family signature 231 248 2.3E-54 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HRM2_RS09320 f2a352e1bfd05772a5b8fae483253cdf 477 PRINTS PR00834 HtrA/DegQ protease family signature 314 326 2.3E-54 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HRM2_RS09320 f2a352e1bfd05772a5b8fae483253cdf 477 PRINTS PR00834 HtrA/DegQ protease family signature 135 155 2.3E-54 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HRM2_RS09320 f2a352e1bfd05772a5b8fae483253cdf 477 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 41 471 1.0E-143 T 22-04-2016 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 HRM2_RS09320 f2a352e1bfd05772a5b8fae483253cdf 477 Pfam PF13365 Trypsin-like peptidase domain 105 238 2.9E-34 T 22-04-2016 HRM2_RS09320 f2a352e1bfd05772a5b8fae483253cdf 477 SMART SM00228 383 466 4.1E-10 T 22-04-2016 IPR001478 PDZ domain GO:0005515 HRM2_RS09320 f2a352e1bfd05772a5b8fae483253cdf 477 SMART SM00228 274 356 4.7E-11 T 22-04-2016 IPR001478 PDZ domain GO:0005515 HRM2_RS09320 f2a352e1bfd05772a5b8fae483253cdf 477 SUPERFAMILY SSF50494 14 65 1.43E-66 T 22-04-2016 IPR009003 Peptidase S1, PA clan HRM2_RS09320 f2a352e1bfd05772a5b8fae483253cdf 477 SUPERFAMILY SSF50494 102 283 1.43E-66 T 22-04-2016 IPR009003 Peptidase S1, PA clan HRM2_RS09320 f2a352e1bfd05772a5b8fae483253cdf 477 Gene3D G3DSA:2.30.42.10 385 472 7.7E-16 T 22-04-2016 IPR001478 PDZ domain GO:0005515 HRM2_RS09320 f2a352e1bfd05772a5b8fae483253cdf 477 Gene3D G3DSA:2.30.42.10 276 370 2.1E-27 T 22-04-2016 IPR001478 PDZ domain GO:0005515 HRM2_RS09320 f2a352e1bfd05772a5b8fae483253cdf 477 SUPERFAMILY SSF50156 258 364 2.76E-21 T 22-04-2016 IPR001478 PDZ domain GO:0005515 HRM2_RS09320 f2a352e1bfd05772a5b8fae483253cdf 477 Gene3D G3DSA:2.40.10.10 167 275 1.2E-44 T 22-04-2016 HRM2_RS13255 6a987ccb7362cdd85b6711d993619aa8 174 SMART SM00738 4 103 3.1E-11 T 22-04-2016 IPR006645 NusG, N-terminal GO:0006355 HRM2_RS13255 6a987ccb7362cdd85b6711d993619aa8 174 Gene3D G3DSA:2.30.30.30 117 167 4.2E-5 T 22-04-2016 IPR014722 Ribosomal protein L2 domain 2 HRM2_RS13255 6a987ccb7362cdd85b6711d993619aa8 174 SUPERFAMILY SSF50104 117 167 1.5E-6 T 22-04-2016 IPR008991 Translation protein SH3-like domain HRM2_RS13255 6a987ccb7362cdd85b6711d993619aa8 174 PANTHER PTHR30265 1 167 4.3E-31 T 22-04-2016 HRM2_RS13255 6a987ccb7362cdd85b6711d993619aa8 174 PANTHER PTHR30265:SF3 1 167 4.3E-31 T 22-04-2016 HRM2_RS13255 6a987ccb7362cdd85b6711d993619aa8 174 SUPERFAMILY SSF82679 4 103 1.96E-24 T 22-04-2016 IPR006645 NusG, N-terminal GO:0006355 HRM2_RS13255 6a987ccb7362cdd85b6711d993619aa8 174 Pfam PF02357 Transcription termination factor nusG 5 99 1.8E-17 T 22-04-2016 IPR006645 NusG, N-terminal GO:0006355 HRM2_RS13255 6a987ccb7362cdd85b6711d993619aa8 174 Gene3D G3DSA:3.30.70.940 4 100 6.5E-14 T 22-04-2016 IPR006645 NusG, N-terminal GO:0006355 HRM2_RS02850 1bfb3f40611408c8f3753012d91aa21e 529 PANTHER PTHR32089 161 255 2.0E-13 T 22-04-2016 HRM2_RS02850 1bfb3f40611408c8f3753012d91aa21e 529 PANTHER PTHR32089 277 447 2.0E-13 T 22-04-2016 HRM2_RS02850 1bfb3f40611408c8f3753012d91aa21e 529 Pfam PF02743 Cache domain 40 330 2.4E-23 T 22-04-2016 IPR033479 Double Cache domain 1 HRM2_RS02850 1bfb3f40611408c8f3753012d91aa21e 529 PANTHER PTHR32089:SF64 161 255 2.0E-13 T 22-04-2016 HRM2_RS02850 1bfb3f40611408c8f3753012d91aa21e 529 PANTHER PTHR32089:SF64 277 447 2.0E-13 T 22-04-2016 HRM2_RS02850 1bfb3f40611408c8f3753012d91aa21e 529 Pfam PF00672 HAMP domain 350 415 2.4E-10 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS02850 1bfb3f40611408c8f3753012d91aa21e 529 SUPERFAMILY SSF158472 369 419 3.01E-5 T 22-04-2016 HRM2_RS02850 1bfb3f40611408c8f3753012d91aa21e 529 Gene3D G3DSA:3.30.450.20 87 128 6.8E-16 T 22-04-2016 HRM2_RS02850 1bfb3f40611408c8f3753012d91aa21e 529 Gene3D G3DSA:3.30.450.20 163 212 6.8E-16 T 22-04-2016 HRM2_RS02280 8b95b0c36134a34c913c81d008919888 814 SMART SM00873 221 394 2.6E-88 T 22-04-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 HRM2_RS02280 8b95b0c36134a34c913c81d008919888 814 SUPERFAMILY SSF55681 476 705 1.47E-44 T 22-04-2016 HRM2_RS02280 8b95b0c36134a34c913c81d008919888 814 Pfam PF03483 B3/4 domain 222 391 6.7E-66 T 22-04-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 HRM2_RS02280 8b95b0c36134a34c913c81d008919888 814 SMART SM00874 411 480 1.7E-22 T 22-04-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20 HRM2_RS02280 8b95b0c36134a34c913c81d008919888 814 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 812 1.2E-248 T 22-04-2016 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 HRM2_RS02280 8b95b0c36134a34c913c81d008919888 814 Pfam PF03147 Ferredoxin-fold anticodon binding domain 718 812 4.1E-22 T 22-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 HRM2_RS02280 8b95b0c36134a34c913c81d008919888 814 Pfam PF01588 Putative tRNA binding domain 45 144 1.2E-20 T 22-04-2016 IPR002547 tRNA-binding domain GO:0000049 Reactome: REACT_71 HRM2_RS02280 8b95b0c36134a34c913c81d008919888 814 PANTHER PTHR10947:SF0 2 813 3.8E-264 T 22-04-2016 HRM2_RS02280 8b95b0c36134a34c913c81d008919888 814 PANTHER PTHR10947 2 813 3.8E-264 T 22-04-2016 HRM2_RS02280 8b95b0c36134a34c913c81d008919888 814 Gene3D G3DSA:3.50.40.10 208 404 3.8E-80 T 22-04-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 HRM2_RS02280 8b95b0c36134a34c913c81d008919888 814 Gene3D G3DSA:3.30.56.10 1 38 1.4E-24 T 22-04-2016 HRM2_RS02280 8b95b0c36134a34c913c81d008919888 814 Gene3D G3DSA:3.30.56.10 154 181 1.4E-24 T 22-04-2016 HRM2_RS02280 8b95b0c36134a34c913c81d008919888 814 Gene3D G3DSA:3.30.56.20 410 484 7.9E-23 T 22-04-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20 HRM2_RS02280 8b95b0c36134a34c913c81d008919888 814 SMART SM00896 718 813 3.6E-26 T 22-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 HRM2_RS02280 8b95b0c36134a34c913c81d008919888 814 SUPERFAMILY SSF54991 714 812 2.09E-22 T 22-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 HRM2_RS02280 8b95b0c36134a34c913c81d008919888 814 Gene3D G3DSA:2.40.50.140 42 152 1.3E-39 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS02280 8b95b0c36134a34c913c81d008919888 814 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 807 42.572 T 22-04-2016 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 HRM2_RS02280 8b95b0c36134a34c913c81d008919888 814 SUPERFAMILY SSF46955 411 484 1.37E-16 T 22-04-2016 IPR009061 Putative DNA-binding domain HRM2_RS02280 8b95b0c36134a34c913c81d008919888 814 SUPERFAMILY SSF50249 42 187 2.6E-43 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS02280 8b95b0c36134a34c913c81d008919888 814 Gene3D G3DSA:3.30.930.10 497 705 6.9E-57 T 22-04-2016 HRM2_RS02280 8b95b0c36134a34c913c81d008919888 814 SUPERFAMILY SSF56037 208 406 2.48E-67 T 22-04-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 HRM2_RS02280 8b95b0c36134a34c913c81d008919888 814 Pfam PF03484 tRNA synthetase B5 domain 414 480 4.3E-16 T 22-04-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20 HRM2_RS02280 8b95b0c36134a34c913c81d008919888 814 Gene3D G3DSA:3.30.70.380 720 812 8.0E-22 T 22-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 HRM2_RS20665 07d492e838055b8187075913902230dc 938 PANTHER PTHR33121:SF10 682 935 1.4E-77 T 22-04-2016 HRM2_RS20665 07d492e838055b8187075913902230dc 938 PANTHER PTHR33121 682 935 1.4E-77 T 22-04-2016 HRM2_RS20665 07d492e838055b8187075913902230dc 938 Pfam PF14827 Double sensory domain of two-component sensor kinase 47 277 9.5E-41 T 22-04-2016 IPR029150 Double Cache domain 3 HRM2_RS20665 07d492e838055b8187075913902230dc 938 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 512 673 1.1E-45 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS20665 07d492e838055b8187075913902230dc 938 Gene3D G3DSA:3.20.20.450 691 934 1.8E-81 T 22-04-2016 IPR001633 EAL domain HRM2_RS20665 07d492e838055b8187075913902230dc 938 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 386 509 7.4E-12 T 22-04-2016 IPR000014 PAS domain HRM2_RS20665 07d492e838055b8187075913902230dc 938 Gene3D G3DSA:3.30.450.20 380 503 2.6E-11 T 22-04-2016 HRM2_RS20665 07d492e838055b8187075913902230dc 938 Pfam PF00990 Diguanylate cyclase, GGDEF domain 514 668 1.2E-43 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS20665 07d492e838055b8187075913902230dc 938 SUPERFAMILY SSF55073 519 676 3.37E-48 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS20665 07d492e838055b8187075913902230dc 938 Gene3D G3DSA:3.30.70.270 515 680 1.0E-53 T 22-04-2016 HRM2_RS20665 07d492e838055b8187075913902230dc 938 Pfam PF00563 EAL domain 694 927 1.2E-72 T 22-04-2016 IPR001633 EAL domain HRM2_RS20665 07d492e838055b8187075913902230dc 938 SUPERFAMILY SSF55785 401 510 1.77E-11 T 22-04-2016 IPR000014 PAS domain HRM2_RS20665 07d492e838055b8187075913902230dc 938 SMART SM00267 503 675 2.9E-54 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS20665 07d492e838055b8187075913902230dc 938 SUPERFAMILY SSF141868 693 933 7.85E-78 T 22-04-2016 IPR001633 EAL domain HRM2_RS20665 07d492e838055b8187075913902230dc 938 SMART SM00052 687 932 8.4E-82 T 22-04-2016 IPR001633 EAL domain HRM2_RS20665 07d492e838055b8187075913902230dc 938 SMART SM00091 388 454 0.0082 T 22-04-2016 IPR000014 PAS domain HRM2_RS07060 575c1b6c3d91b717f5a5175c50b59d92 589 Gene3D G3DSA:3.30.450.20 19 118 2.1E-4 T 22-04-2016 HRM2_RS07060 575c1b6c3d91b717f5a5175c50b59d92 589 SMART SM00091 135 201 1.5E-4 T 22-04-2016 IPR000014 PAS domain HRM2_RS07060 575c1b6c3d91b717f5a5175c50b59d92 589 Pfam PF02954 Bacterial regulatory protein, Fis family 548 586 1.7E-5 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS07060 575c1b6c3d91b717f5a5175c50b59d92 589 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 301 314 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS07060 575c1b6c3d91b717f5a5175c50b59d92 589 Gene3D G3DSA:3.40.50.300 274 449 8.0E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07060 575c1b6c3d91b717f5a5175c50b59d92 589 Pfam PF00158 Sigma-54 interaction domain 278 443 8.4E-65 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS07060 575c1b6c3d91b717f5a5175c50b59d92 589 Gene3D G3DSA:1.10.10.60 537 588 6.2E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS07060 575c1b6c3d91b717f5a5175c50b59d92 589 Gene3D G3DSA:3.30.450.20 136 253 4.8E-15 T 22-04-2016 HRM2_RS07060 575c1b6c3d91b717f5a5175c50b59d92 589 SUPERFAMILY SSF46689 540 588 1.66E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS07060 575c1b6c3d91b717f5a5175c50b59d92 589 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 137 249 5.0E-13 T 22-04-2016 IPR000014 PAS domain HRM2_RS07060 575c1b6c3d91b717f5a5175c50b59d92 589 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 491 500 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS07060 575c1b6c3d91b717f5a5175c50b59d92 589 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 363 378 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS07060 575c1b6c3d91b717f5a5175c50b59d92 589 SMART SM00382 297 440 2.4E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS07060 575c1b6c3d91b717f5a5175c50b59d92 589 PANTHER PTHR32071 229 588 6.0E-125 T 22-04-2016 HRM2_RS07060 575c1b6c3d91b717f5a5175c50b59d92 589 SUPERFAMILY SSF55785 127 235 2.09E-13 T 22-04-2016 IPR000014 PAS domain HRM2_RS07060 575c1b6c3d91b717f5a5175c50b59d92 589 Gene3D G3DSA:1.10.8.60 450 527 1.1E-17 T 22-04-2016 HRM2_RS07060 575c1b6c3d91b717f5a5175c50b59d92 589 SUPERFAMILY SSF52540 285 520 4.88E-65 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07060 575c1b6c3d91b717f5a5175c50b59d92 589 Pfam PF13426 PAS domain 146 242 2.2E-11 T 22-04-2016 IPR000014 PAS domain HRM2_RS23270 321de3db605adce1b6e9b25b04461613 258 Gene3D G3DSA:3.90.226.10 1 198 4.3E-60 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS23270 321de3db605adce1b6e9b25b04461613 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 257 4.8E-58 T 22-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 HRM2_RS23270 321de3db605adce1b6e9b25b04461613 258 Gene3D G3DSA:1.10.12.10 204 258 9.5E-11 T 22-04-2016 IPR014748 Crontonase, C-terminal HRM2_RS23270 321de3db605adce1b6e9b25b04461613 258 SUPERFAMILY SSF52096 1 258 6.88E-77 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS23270 321de3db605adce1b6e9b25b04461613 258 PANTHER PTHR11941:SF28 4 255 2.8E-104 T 22-04-2016 HRM2_RS23270 321de3db605adce1b6e9b25b04461613 258 PANTHER PTHR11941 4 255 2.8E-104 T 22-04-2016 HRM2_RS11365 fc49d813ae66961e8d62698b97056716 837 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 701 827 4.9E-19 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HRM2_RS11365 fc49d813ae66961e8d62698b97056716 837 Gene3D G3DSA:3.40.50.720 427 565 5.2E-9 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS11365 fc49d813ae66961e8d62698b97056716 837 Pfam PF02080 TrkA-C domain 578 637 1.1E-10 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS11365 fc49d813ae66961e8d62698b97056716 837 Pfam PF00999 Sodium/hydrogen exchanger family 25 403 3.4E-19 T 22-04-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 HRM2_RS11365 fc49d813ae66961e8d62698b97056716 837 Gene3D G3DSA:3.40.930.10 687 829 6.4E-24 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HRM2_RS11365 fc49d813ae66961e8d62698b97056716 837 PANTHER PTHR32507 1 665 3.8E-107 T 22-04-2016 HRM2_RS11365 fc49d813ae66961e8d62698b97056716 837 PANTHER PTHR32507:SF10 1 665 3.8E-107 T 22-04-2016 HRM2_RS11365 fc49d813ae66961e8d62698b97056716 837 SUPERFAMILY SSF51735 427 565 3.15E-7 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS11365 fc49d813ae66961e8d62698b97056716 837 SUPERFAMILY SSF116726 569 637 4.97E-10 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS11365 fc49d813ae66961e8d62698b97056716 837 Gene3D G3DSA:3.30.70.1450 582 636 1.5E-5 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS11365 fc49d813ae66961e8d62698b97056716 837 SUPERFAMILY SSF55804 691 825 1.57E-19 T 22-04-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 HRM2_RS15175 38b987692edd21473c934eb975983b86 314 SUPERFAMILY SSF54862 17 163 7.53E-18 T 22-04-2016 HRM2_RS15175 38b987692edd21473c934eb975983b86 314 Gene3D G3DSA:1.10.1060.10 4 85 5.4E-15 T 22-04-2016 HRM2_RS15175 38b987692edd21473c934eb975983b86 314 Pfam PF02662 Methyl-viologen-reducing hydrogenase, delta subunit 190 309 9.2E-31 T 22-04-2016 IPR003813 Methyl-viologen-reducing hydrogenase, delta subunit GO:0015948|GO:0055114 HRM2_RS15175 38b987692edd21473c934eb975983b86 314 Gene3D G3DSA:3.30.70.20 123 164 6.3E-13 T 22-04-2016 HRM2_RS15175 38b987692edd21473c934eb975983b86 314 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 146 157 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS15175 38b987692edd21473c934eb975983b86 314 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 21 32 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS15175 38b987692edd21473c934eb975983b86 314 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 117 128 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS15175 38b987692edd21473c934eb975983b86 314 Pfam PF00037 4Fe-4S binding domain 140 162 6.6E-6 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS15175 38b987692edd21473c934eb975983b86 314 Pfam PF00037 4Fe-4S binding domain 114 131 5.9E-5 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS15175 38b987692edd21473c934eb975983b86 314 PANTHER PTHR32479 10 100 2.2E-14 T 22-04-2016 HRM2_RS15175 38b987692edd21473c934eb975983b86 314 Gene3D G3DSA:3.30.70.20 86 122 3.2E-6 T 22-04-2016 HRM2_RS15175 38b987692edd21473c934eb975983b86 314 PANTHER PTHR32479:SF2 10 100 2.2E-14 T 22-04-2016 HRM2_RS15175 38b987692edd21473c934eb975983b86 314 Pfam PF13534 4Fe-4S dicluster domain 21 86 3.5E-10 T 22-04-2016 HRM2_RS10065 4650c0b030b98aa255285c10aa342007 333 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 157 185 - T 22-04-2016 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 HRM2_RS10065 4650c0b030b98aa255285c10aa342007 333 SUPERFAMILY SSF52283 9 141 1.15E-28 T 22-04-2016 HRM2_RS10065 4650c0b030b98aa255285c10aa342007 333 Gene3D G3DSA:3.40.50.720 117 297 3.5E-60 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS10065 4650c0b030b98aa255285c10aa342007 333 SUPERFAMILY SSF51735 109 297 4.12E-54 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS10065 4650c0b030b98aa255285c10aa342007 333 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 117 296 7.2E-56 T 22-04-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 HRM2_RS10065 4650c0b030b98aa255285c10aa342007 333 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 12 328 1.5E-28 T 22-04-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 HRM2_RS10065 4650c0b030b98aa255285c10aa342007 333 Gene3D G3DSA:3.40.50.720 10 116 4.0E-31 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS10065 4650c0b030b98aa255285c10aa342007 333 PANTHER PTHR10996 9 333 5.5E-114 T 22-04-2016 HRM2_RS05640 d1b328707c660d848ae6bb1218cc68c7 234 SUPERFAMILY SSF53335 8 229 3.01E-39 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS05640 d1b328707c660d848ae6bb1218cc68c7 234 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 3 233 32.985 T 22-04-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 HRM2_RS05640 d1b328707c660d848ae6bb1218cc68c7 234 Pfam PF01209 ubiE/COQ5 methyltransferase family 8 233 2.3E-58 T 22-04-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 HRM2_RS05640 d1b328707c660d848ae6bb1218cc68c7 234 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 8 233 8.4E-71 T 22-04-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 HRM2_RS05640 d1b328707c660d848ae6bb1218cc68c7 234 PANTHER PTHR10108:SF24 8 233 3.3E-56 T 22-04-2016 HRM2_RS05640 d1b328707c660d848ae6bb1218cc68c7 234 Gene3D G3DSA:3.40.50.150 9 227 2.0E-41 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS05640 d1b328707c660d848ae6bb1218cc68c7 234 PANTHER PTHR10108 8 233 3.3E-56 T 22-04-2016 HRM2_RS05640 d1b328707c660d848ae6bb1218cc68c7 234 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 19 34 - T 22-04-2016 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 HRM2_RS12520 ec015bd6415874873c1326d34d34458b 419 PANTHER PTHR30124:SF2 79 385 3.6E-28 T 22-04-2016 HRM2_RS12520 ec015bd6415874873c1326d34d34458b 419 PANTHER PTHR30124 79 385 3.6E-28 T 22-04-2016 HRM2_RS12520 ec015bd6415874873c1326d34d34458b 419 Pfam PF13657 HipA N-terminal domain 16 115 1.3E-16 T 22-04-2016 IPR017508 HipA, N-terminal subdomain 1 HRM2_RS12520 ec015bd6415874873c1326d34d34458b 419 Pfam PF07804 HipA-like C-terminal domain 247 379 7.2E-24 T 22-04-2016 IPR012893 HipA-like, C-terminal HRM2_RS12520 ec015bd6415874873c1326d34d34458b 419 Pfam PF07805 HipA-like N-terminal domain 158 242 2.5E-17 T 22-04-2016 IPR012894 HipA, N-terminal subdomain 2 HRM2_RS12425 f7890b0ecdfb54b3cf76c78a696ff658 132 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 10 131 29.367 T 22-04-2016 IPR002930 Glycine cleavage system H-protein HRM2_RS12425 f7890b0ecdfb54b3cf76c78a696ff658 132 Gene3D G3DSA:2.40.50.100 12 131 1.8E-51 T 22-04-2016 HRM2_RS12425 f7890b0ecdfb54b3cf76c78a696ff658 132 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 53 82 - T 22-04-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site HRM2_RS12425 f7890b0ecdfb54b3cf76c78a696ff658 132 SUPERFAMILY SSF51230 9 131 6.04E-44 T 22-04-2016 IPR011053 Single hybrid motif HRM2_RS12425 f7890b0ecdfb54b3cf76c78a696ff658 132 Pfam PF01597 Glycine cleavage H-protein 14 130 4.8E-46 T 22-04-2016 IPR002930 Glycine cleavage system H-protein HRM2_RS12425 f7890b0ecdfb54b3cf76c78a696ff658 132 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 9 131 3.2E-47 T 22-04-2016 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 HRM2_RS12425 f7890b0ecdfb54b3cf76c78a696ff658 132 PANTHER PTHR11715 4 131 2.0E-63 T 22-04-2016 IPR002930 Glycine cleavage system H-protein HRM2_RS05185 cd7fb9e2192be7d94b31c0fed7c01e7e 410 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 310 401 2.0E-6 T 22-04-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 HRM2_RS05185 cd7fb9e2192be7d94b31c0fed7c01e7e 410 SUPERFAMILY SSF51419 42 306 1.06E-39 T 22-04-2016 IPR029066 PLP-binding barrel HRM2_RS05185 cd7fb9e2192be7d94b31c0fed7c01e7e 410 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 61 303 5.0E-21 T 22-04-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Reactome: REACT_13 HRM2_RS05185 cd7fb9e2192be7d94b31c0fed7c01e7e 410 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 95 107 9.9E-8 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 HRM2_RS05185 cd7fb9e2192be7d94b31c0fed7c01e7e 410 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 390 403 9.9E-8 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 HRM2_RS05185 cd7fb9e2192be7d94b31c0fed7c01e7e 410 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 294 313 9.9E-8 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 HRM2_RS05185 cd7fb9e2192be7d94b31c0fed7c01e7e 410 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 75 93 9.9E-8 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 HRM2_RS05185 cd7fb9e2192be7d94b31c0fed7c01e7e 410 PANTHER PTHR11482 24 410 8.8E-37 T 22-04-2016 HRM2_RS05185 cd7fb9e2192be7d94b31c0fed7c01e7e 410 SUPERFAMILY SSF50621 285 408 1.3E-22 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 HRM2_RS05185 cd7fb9e2192be7d94b31c0fed7c01e7e 410 Gene3D G3DSA:2.40.37.10 296 402 3.3E-17 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 HRM2_RS05185 cd7fb9e2192be7d94b31c0fed7c01e7e 410 PANTHER PTHR11482:SF5 24 410 8.8E-37 T 22-04-2016 HRM2_RS05185 cd7fb9e2192be7d94b31c0fed7c01e7e 410 Gene3D G3DSA:3.20.20.10 51 295 1.0E-41 T 22-04-2016 IPR029066 PLP-binding barrel HRM2_RS01190 eeea74f486b958742e2cfd5f9d21710d 253 SUPERFAMILY SSF52540 9 241 2.48E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01190 eeea74f486b958742e2cfd5f9d21710d 253 Gene3D G3DSA:3.40.50.300 10 247 6.5E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01190 eeea74f486b958742e2cfd5f9d21710d 253 Pfam PF00005 ABC transporter 23 177 9.8E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS01190 eeea74f486b958742e2cfd5f9d21710d 253 SMART SM00382 31 224 8.4E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS01190 eeea74f486b958742e2cfd5f9d21710d 253 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 7 253 5.3E-120 T 22-04-2016 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 HRM2_RS01190 eeea74f486b958742e2cfd5f9d21710d 253 PANTHER PTHR24220:SF585 8 251 9.8E-131 T 22-04-2016 HRM2_RS01190 eeea74f486b958742e2cfd5f9d21710d 253 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS01190 eeea74f486b958742e2cfd5f9d21710d 253 PANTHER PTHR24220 8 251 9.8E-131 T 22-04-2016 HRM2_RS23145 eb99ecf9dbfe97127ecf8e5eba77a6f6 450 SMART SM00448 5 116 1.0E-36 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS23145 eb99ecf9dbfe97127ecf8e5eba77a6f6 450 Gene3D G3DSA:3.40.50.2300 3 128 1.2E-40 T 22-04-2016 HRM2_RS23145 eb99ecf9dbfe97127ecf8e5eba77a6f6 450 SUPERFAMILY SSF46689 358 445 2.28E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS23145 eb99ecf9dbfe97127ecf8e5eba77a6f6 450 Pfam PF02954 Bacterial regulatory protein, Fis family 404 440 1.4E-9 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS23145 eb99ecf9dbfe97127ecf8e5eba77a6f6 450 Gene3D G3DSA:1.10.10.60 393 445 4.0E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS23145 eb99ecf9dbfe97127ecf8e5eba77a6f6 450 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 358 367 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS23145 eb99ecf9dbfe97127ecf8e5eba77a6f6 450 SMART SM00382 165 308 2.3E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS23145 eb99ecf9dbfe97127ecf8e5eba77a6f6 450 SUPERFAMILY SSF52172 4 189 3.84E-47 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS23145 eb99ecf9dbfe97127ecf8e5eba77a6f6 450 PANTHER PTHR32071 1 448 1.5E-190 T 22-04-2016 HRM2_RS23145 eb99ecf9dbfe97127ecf8e5eba77a6f6 450 Gene3D G3DSA:1.10.8.60 318 392 2.5E-26 T 22-04-2016 HRM2_RS23145 eb99ecf9dbfe97127ecf8e5eba77a6f6 450 Gene3D G3DSA:3.40.50.300 141 317 1.5E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23145 eb99ecf9dbfe97127ecf8e5eba77a6f6 450 Pfam PF00158 Sigma-54 interaction domain 145 311 2.4E-66 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS23145 eb99ecf9dbfe97127ecf8e5eba77a6f6 450 PANTHER PTHR32071:SF18 1 448 1.5E-190 T 22-04-2016 HRM2_RS23145 eb99ecf9dbfe97127ecf8e5eba77a6f6 450 Pfam PF00072 Response regulator receiver domain 7 113 2.9E-30 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS23145 eb99ecf9dbfe97127ecf8e5eba77a6f6 450 SUPERFAMILY SSF52540 144 386 9.91E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23145 eb99ecf9dbfe97127ecf8e5eba77a6f6 450 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 169 182 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS01955 2ccff81eebf8cf0c08265389c8c039dd 297 PANTHER PTHR30163 184 263 2.1E-38 T 22-04-2016 IPR011757 Lytic transglycosylase MltB HRM2_RS01955 2ccff81eebf8cf0c08265389c8c039dd 297 PANTHER PTHR30163 88 156 2.1E-38 T 22-04-2016 IPR011757 Lytic transglycosylase MltB HRM2_RS01955 2ccff81eebf8cf0c08265389c8c039dd 297 SUPERFAMILY SSF53955 33 157 7.88E-52 T 22-04-2016 IPR023346 Lysozyme-like domain HRM2_RS01955 2ccff81eebf8cf0c08265389c8c039dd 297 SUPERFAMILY SSF53955 185 296 7.88E-52 T 22-04-2016 IPR023346 Lysozyme-like domain HRM2_RS01955 2ccff81eebf8cf0c08265389c8c039dd 297 PANTHER PTHR30163:SF0 184 263 2.1E-38 T 22-04-2016 HRM2_RS01955 2ccff81eebf8cf0c08265389c8c039dd 297 PANTHER PTHR30163:SF0 88 156 2.1E-38 T 22-04-2016 HRM2_RS01955 2ccff81eebf8cf0c08265389c8c039dd 297 Gene3D G3DSA:1.10.530.10 65 138 3.1E-34 T 22-04-2016 HRM2_RS01955 2ccff81eebf8cf0c08265389c8c039dd 297 Gene3D G3DSA:1.10.530.10 205 280 3.1E-34 T 22-04-2016 HRM2_RS01955 2ccff81eebf8cf0c08265389c8c039dd 297 Pfam PF13406 Transglycosylase SLT domain 40 265 2.6E-60 T 22-04-2016 IPR031304 Transglycosylase SLT domain 2 HRM2_RS18585 420bd72f70a588b332ceebe8721d3e0e 636 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 319 522 1.4E-38 T 22-04-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS18585 420bd72f70a588b332ceebe8721d3e0e 636 Pfam PF03129 Anticodon binding domain 535 620 2.1E-19 T 22-04-2016 IPR004154 Anticodon-binding HRM2_RS18585 420bd72f70a588b332ceebe8721d3e0e 636 Gene3D G3DSA:3.40.50.800 525 630 8.4E-31 T 22-04-2016 IPR004154 Anticodon-binding HRM2_RS18585 420bd72f70a588b332ceebe8721d3e0e 636 Gene3D G3DSA:3.30.930.10 237 524 2.3E-119 T 22-04-2016 HRM2_RS18585 420bd72f70a588b332ceebe8721d3e0e 636 Gene3D G3DSA:3.10.20.30 1 64 3.9E-17 T 22-04-2016 IPR012675 Beta-grasp domain HRM2_RS18585 420bd72f70a588b332ceebe8721d3e0e 636 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 622 6.1E-211 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HRM2_RS18585 420bd72f70a588b332ceebe8721d3e0e 636 PANTHER PTHR11451:SF31 1 636 0.0 T 22-04-2016 HRM2_RS18585 420bd72f70a588b332ceebe8721d3e0e 636 Gene3D G3DSA:3.30.980.10 183 218 2.3E-34 T 22-04-2016 HRM2_RS18585 420bd72f70a588b332ceebe8721d3e0e 636 Gene3D G3DSA:3.30.980.10 66 128 2.3E-34 T 22-04-2016 HRM2_RS18585 420bd72f70a588b332ceebe8721d3e0e 636 SMART SM00863 165 214 2.3E-20 T 22-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 HRM2_RS18585 420bd72f70a588b332ceebe8721d3e0e 636 PRINTS PR01047 Threonyl-tRNA synthetase signature 528 540 2.6E-51 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HRM2_RS18585 420bd72f70a588b332ceebe8721d3e0e 636 PRINTS PR01047 Threonyl-tRNA synthetase signature 357 380 2.6E-51 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HRM2_RS18585 420bd72f70a588b332ceebe8721d3e0e 636 PRINTS PR01047 Threonyl-tRNA synthetase signature 501 514 2.6E-51 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HRM2_RS18585 420bd72f70a588b332ceebe8721d3e0e 636 PRINTS PR01047 Threonyl-tRNA synthetase signature 324 352 2.6E-51 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HRM2_RS18585 420bd72f70a588b332ceebe8721d3e0e 636 PRINTS PR01047 Threonyl-tRNA synthetase signature 458 486 2.6E-51 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HRM2_RS18585 420bd72f70a588b332ceebe8721d3e0e 636 SUPERFAMILY SSF81271 2 61 3.71E-12 T 22-04-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 HRM2_RS18585 420bd72f70a588b332ceebe8721d3e0e 636 Gene3D G3DSA:3.30.54.20 130 182 6.2E-24 T 22-04-2016 HRM2_RS18585 420bd72f70a588b332ceebe8721d3e0e 636 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 165 214 1.3E-12 T 22-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 HRM2_RS18585 420bd72f70a588b332ceebe8721d3e0e 636 PANTHER PTHR11451 1 636 0.0 T 22-04-2016 HRM2_RS18585 420bd72f70a588b332ceebe8721d3e0e 636 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 628 32.716 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HRM2_RS18585 420bd72f70a588b332ceebe8721d3e0e 636 SUPERFAMILY SSF52954 524 627 2.27E-27 T 22-04-2016 IPR004154 Anticodon-binding HRM2_RS18585 420bd72f70a588b332ceebe8721d3e0e 636 SUPERFAMILY SSF55681 238 520 5.39E-95 T 22-04-2016 HRM2_RS18585 420bd72f70a588b332ceebe8721d3e0e 636 SUPERFAMILY SSF55186 64 236 1.83E-60 T 22-04-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 HRM2_RS18585 420bd72f70a588b332ceebe8721d3e0e 636 Pfam PF02824 TGS domain 2 61 1.9E-5 T 22-04-2016 IPR004095 TGS KEGG: 00970+6.1.1.3 HRM2_RS12310 e92f00771a35fb4f6bb22937e154c98d 231 PANTHER PTHR21299 5 226 3.3E-51 T 22-04-2016 HRM2_RS12310 e92f00771a35fb4f6bb22937e154c98d 231 Gene3D G3DSA:3.40.50.300 3 215 1.4E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12310 e92f00771a35fb4f6bb22937e154c98d 231 Hamap MF_00238 Cytidylate kinase [cmk]. 4 218 31.252 T 22-04-2016 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 HRM2_RS12310 e92f00771a35fb4f6bb22937e154c98d 231 SUPERFAMILY SSF52540 1 216 3.92E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12310 e92f00771a35fb4f6bb22937e154c98d 231 Pfam PF02224 Cytidylate kinase 6 215 2.5E-64 T 22-04-2016 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 HRM2_RS12310 e92f00771a35fb4f6bb22937e154c98d 231 TIGRFAM TIGR00017 cmk: cytidylate kinase 5 213 1.1E-64 T 22-04-2016 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 HRM2_RS12880 ca1fd903c33215e53818f7a830936f28 855 Pfam PF01751 Toprim domain 3 121 1.9E-10 T 22-04-2016 IPR006171 Toprim domain HRM2_RS12880 ca1fd903c33215e53818f7a830936f28 855 Pfam PF13342 C-terminal repeat of topoisomerase 642 703 2.9E-17 T 22-04-2016 IPR025589 Topoisomerase C-terminal repeat HRM2_RS12880 ca1fd903c33215e53818f7a830936f28 855 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 305 320 - T 22-04-2016 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 HRM2_RS12880 ca1fd903c33215e53818f7a830936f28 855 TIGRFAM TIGR01056 topB: DNA topoisomerase III 2 690 7.9E-165 T 22-04-2016 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 HRM2_RS12880 ca1fd903c33215e53818f7a830936f28 855 SUPERFAMILY SSF56712 4 600 2.49E-152 T 22-04-2016 IPR023405 DNA topoisomerase, type IA, core domain HRM2_RS12880 ca1fd903c33215e53818f7a830936f28 855 PANTHER PTHR11390 509 627 1.5E-136 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 HRM2_RS12880 ca1fd903c33215e53818f7a830936f28 855 PANTHER PTHR11390 1 491 1.5E-136 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 HRM2_RS12880 ca1fd903c33215e53818f7a830936f28 855 SMART SM00493 2 125 3.4E-15 T 22-04-2016 IPR006171 Toprim domain HRM2_RS12880 ca1fd903c33215e53818f7a830936f28 855 Gene3D G3DSA:1.10.460.10 469 600 8.9E-45 T 22-04-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 HRM2_RS12880 ca1fd903c33215e53818f7a830936f28 855 Gene3D G3DSA:1.10.460.10 158 211 8.9E-45 T 22-04-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 HRM2_RS12880 ca1fd903c33215e53818f7a830936f28 855 Pfam PF01131 DNA topoisomerase 155 585 4.4E-112 T 22-04-2016 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HRM2_RS12880 ca1fd903c33215e53818f7a830936f28 855 SMART SM00437 268 546 2.5E-60 T 22-04-2016 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 HRM2_RS12880 ca1fd903c33215e53818f7a830936f28 855 PANTHER PTHR11390:SF21 509 627 1.5E-136 T 22-04-2016 HRM2_RS12880 ca1fd903c33215e53818f7a830936f28 855 PANTHER PTHR11390:SF21 1 491 1.5E-136 T 22-04-2016 HRM2_RS12880 ca1fd903c33215e53818f7a830936f28 855 Gene3D G3DSA:2.70.20.10 356 468 6.1E-19 T 22-04-2016 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 HRM2_RS12880 ca1fd903c33215e53818f7a830936f28 855 Gene3D G3DSA:2.70.20.10 212 323 4.5E-21 T 22-04-2016 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 HRM2_RS12880 ca1fd903c33215e53818f7a830936f28 855 SMART SM00436 127 218 2.2E-17 T 22-04-2016 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 HRM2_RS12880 ca1fd903c33215e53818f7a830936f28 855 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 188 206 1.3E-23 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 HRM2_RS12880 ca1fd903c33215e53818f7a830936f28 855 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 99 112 1.3E-23 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 HRM2_RS12880 ca1fd903c33215e53818f7a830936f28 855 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 311 320 1.3E-23 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 HRM2_RS12880 ca1fd903c33215e53818f7a830936f28 855 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 391 407 1.3E-23 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 HRM2_RS12880 ca1fd903c33215e53818f7a830936f28 855 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 509 523 1.3E-23 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 HRM2_RS12880 ca1fd903c33215e53818f7a830936f28 855 Gene3D G3DSA:3.40.50.140 3 155 1.4E-35 T 22-04-2016 IPR006171 Toprim domain HRM2_RS01375 bafc65a936b6a9310177d2f0a63dd633 304 PANTHER PTHR12715 6 296 5.0E-53 T 22-04-2016 HRM2_RS01375 bafc65a936b6a9310177d2f0a63dd633 304 Pfam PF00892 EamA-like transporter family 156 289 2.9E-23 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS01375 bafc65a936b6a9310177d2f0a63dd633 304 Pfam PF00892 EamA-like transporter family 12 141 7.4E-18 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS01375 bafc65a936b6a9310177d2f0a63dd633 304 SUPERFAMILY SSF103481 198 295 5.89E-16 T 22-04-2016 HRM2_RS01375 bafc65a936b6a9310177d2f0a63dd633 304 SUPERFAMILY SSF103481 49 144 5.23E-10 T 22-04-2016 HRM2_RS19260 02667f41a15f3c822eb4e7e11cc3a231 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.4E-6 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HRM2_RS19260 02667f41a15f3c822eb4e7e11cc3a231 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.4E-6 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HRM2_RS19260 02667f41a15f3c822eb4e7e11cc3a231 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.4E-6 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HRM2_RS19260 02667f41a15f3c822eb4e7e11cc3a231 320 Pfam PF03466 LysR substrate binding domain 89 300 5.5E-30 T 22-04-2016 IPR005119 LysR, substrate-binding HRM2_RS19260 02667f41a15f3c822eb4e7e11cc3a231 320 Gene3D G3DSA:1.10.10.10 4 82 5.1E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS19260 02667f41a15f3c822eb4e7e11cc3a231 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 7.8E-18 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HRM2_RS19260 02667f41a15f3c822eb4e7e11cc3a231 320 PANTHER PTHR30126 3 319 6.5E-56 T 22-04-2016 HRM2_RS19260 02667f41a15f3c822eb4e7e11cc3a231 320 SUPERFAMILY SSF53850 91 308 4.44E-30 T 22-04-2016 HRM2_RS19260 02667f41a15f3c822eb4e7e11cc3a231 320 SUPERFAMILY SSF46785 2 112 4.54E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS19260 02667f41a15f3c822eb4e7e11cc3a231 320 PANTHER PTHR30126:SF11 3 319 6.5E-56 T 22-04-2016 HRM2_RS19260 02667f41a15f3c822eb4e7e11cc3a231 320 Gene3D G3DSA:3.40.190.10 89 238 1.8E-26 T 22-04-2016 HRM2_RS05085 f6911ceda441a10c783d6afca5c6307b 211 SUPERFAMILY SSF55469 1 206 5.37E-51 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 HRM2_RS05085 f6911ceda441a10c783d6afca5c6307b 211 Gene3D G3DSA:3.40.109.10 1 206 2.5E-60 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 HRM2_RS05085 f6911ceda441a10c783d6afca5c6307b 211 PANTHER PTHR23026:SF90 1 205 2.0E-41 T 22-04-2016 HRM2_RS05085 f6911ceda441a10c783d6afca5c6307b 211 Pfam PF00881 Nitroreductase family 7 186 2.8E-32 T 22-04-2016 IPR029479 Nitroreductase HRM2_RS05085 f6911ceda441a10c783d6afca5c6307b 211 PANTHER PTHR23026 1 205 2.0E-41 T 22-04-2016 HRM2_RS21895 203c069d76f1a8a9f0042ac4597150a9 233 SUPERFAMILY SSF53098 76 226 7.74E-36 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS21895 203c069d76f1a8a9f0042ac4597150a9 233 Pfam PF13276 HTH-like domain 4 51 6.7E-12 T 22-04-2016 IPR025948 HTH-like domain HRM2_RS21895 203c069d76f1a8a9f0042ac4597150a9 233 PANTHER PTHR32552 1 222 7.4E-23 T 22-04-2016 HRM2_RS21895 203c069d76f1a8a9f0042ac4597150a9 233 Pfam PF00665 Integrase core domain 75 184 1.0E-21 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 HRM2_RS21895 203c069d76f1a8a9f0042ac4597150a9 233 Gene3D G3DSA:3.30.420.10 71 222 1.3E-31 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS06445 8da3d10cb6a86b29a0807d16bdd77717 568 Pfam PF04773 FecR protein 138 238 2.3E-10 T 22-04-2016 IPR006860 FecR protein HRM2_RS06445 8da3d10cb6a86b29a0807d16bdd77717 568 PANTHER PTHR38731:SF1 64 272 2.3E-15 T 22-04-2016 HRM2_RS06445 8da3d10cb6a86b29a0807d16bdd77717 568 Gene3D G3DSA:3.10.350.10 49 94 4.1E-6 T 22-04-2016 IPR018392 LysM domain HRM2_RS06445 8da3d10cb6a86b29a0807d16bdd77717 568 Pfam PF01476 LysM domain 49 94 3.0E-7 T 22-04-2016 IPR018392 LysM domain HRM2_RS06445 8da3d10cb6a86b29a0807d16bdd77717 568 SMART SM00257 47 94 2.8E-4 T 22-04-2016 IPR018392 LysM domain HRM2_RS06445 8da3d10cb6a86b29a0807d16bdd77717 568 PANTHER PTHR38731 64 272 2.3E-15 T 22-04-2016 HRM2_RS06445 8da3d10cb6a86b29a0807d16bdd77717 568 SUPERFAMILY SSF54106 49 94 4.05E-5 T 22-04-2016 IPR018392 LysM domain HRM2_RS22710 87dec653255c9e555a426cb690cf28ba 466 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 229 244 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS22710 87dec653255c9e555a426cb690cf28ba 466 Gene3D G3DSA:3.40.50.300 140 314 5.8E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22710 87dec653255c9e555a426cb690cf28ba 466 Gene3D G3DSA:1.10.8.60 316 385 8.1E-22 T 22-04-2016 HRM2_RS22710 87dec653255c9e555a426cb690cf28ba 466 SUPERFAMILY SSF46689 356 456 8.06E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS22710 87dec653255c9e555a426cb690cf28ba 466 Pfam PF00158 Sigma-54 interaction domain 142 310 3.7E-64 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS22710 87dec653255c9e555a426cb690cf28ba 466 Gene3D G3DSA:1.10.10.60 407 456 6.7E-5 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS22710 87dec653255c9e555a426cb690cf28ba 466 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 166 179 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS22710 87dec653255c9e555a426cb690cf28ba 466 SUPERFAMILY SSF52540 141 384 9.8E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22710 87dec653255c9e555a426cb690cf28ba 466 Pfam PF00072 Response regulator receiver domain 6 109 2.9E-25 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS22710 87dec653255c9e555a426cb690cf28ba 466 SUPERFAMILY SSF52172 3 186 7.12E-38 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS22710 87dec653255c9e555a426cb690cf28ba 466 SMART SM00448 3 113 2.3E-29 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS22710 87dec653255c9e555a426cb690cf28ba 466 PANTHER PTHR32071 1 457 1.3E-163 T 22-04-2016 HRM2_RS22710 87dec653255c9e555a426cb690cf28ba 466 SMART SM00382 162 306 8.2E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS22710 87dec653255c9e555a426cb690cf28ba 466 Gene3D G3DSA:3.40.50.2300 2 125 5.9E-32 T 22-04-2016 HRM2_RS06760 7732e00d04ebb00245077c178ee66d05 308 PANTHER PTHR12715 7 291 3.5E-58 T 22-04-2016 HRM2_RS06760 7732e00d04ebb00245077c178ee66d05 308 Pfam PF00892 EamA-like transporter family 9 147 1.8E-18 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS06760 7732e00d04ebb00245077c178ee66d05 308 Pfam PF00892 EamA-like transporter family 156 288 1.4E-19 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS06760 7732e00d04ebb00245077c178ee66d05 308 SUPERFAMILY SSF103481 42 150 2.35E-7 T 22-04-2016 HRM2_RS06760 7732e00d04ebb00245077c178ee66d05 308 PANTHER PTHR12715:SF8 7 291 3.5E-58 T 22-04-2016 HRM2_RS06760 7732e00d04ebb00245077c178ee66d05 308 SUPERFAMILY SSF103481 197 291 7.45E-13 T 22-04-2016 HRM2_RS03315 15562f7606c377f9e6ad89decdb89433 871 SMART SM00471 438 586 6.3E-5 T 22-04-2016 IPR003607 HD/PDEase domain HRM2_RS03315 15562f7606c377f9e6ad89decdb89433 871 SUPERFAMILY SSF55021 681 745 2.29E-6 T 22-04-2016 HRM2_RS03315 15562f7606c377f9e6ad89decdb89433 871 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 871 154.257 T 22-04-2016 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 HRM2_RS03315 15562f7606c377f9e6ad89decdb89433 871 Pfam PF01966 HD domain 443 575 1.7E-8 T 22-04-2016 IPR006674 HD domain HRM2_RS03315 15562f7606c377f9e6ad89decdb89433 871 SUPERFAMILY SSF109604 408 617 2.51E-19 T 22-04-2016 HRM2_RS03315 15562f7606c377f9e6ad89decdb89433 871 PANTHER PTHR13734:SF45 351 678 5.1E-63 T 22-04-2016 HRM2_RS03315 15562f7606c377f9e6ad89decdb89433 871 SUPERFAMILY SSF55021 792 862 1.04E-5 T 22-04-2016 HRM2_RS03315 15562f7606c377f9e6ad89decdb89433 871 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 36 863 3.7E-175 T 22-04-2016 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 HRM2_RS03315 15562f7606c377f9e6ad89decdb89433 871 Gene3D G3DSA:3.30.70.260 684 761 8.7E-6 T 22-04-2016 HRM2_RS03315 15562f7606c377f9e6ad89decdb89433 871 Gene3D G3DSA:3.30.70.260 792 852 4.3E-6 T 22-04-2016 HRM2_RS03315 15562f7606c377f9e6ad89decdb89433 871 SUPERFAMILY SSF81593 188 301 8.63E-10 T 22-04-2016 HRM2_RS03315 15562f7606c377f9e6ad89decdb89433 871 SUPERFAMILY SSF81301 35 155 3.31E-16 T 22-04-2016 HRM2_RS03315 15562f7606c377f9e6ad89decdb89433 871 PANTHER PTHR13734 351 678 5.1E-63 T 22-04-2016 HRM2_RS03315 15562f7606c377f9e6ad89decdb89433 871 Pfam PF08335 GlnD PII-uridylyltransferase 170 303 5.4E-27 T 22-04-2016 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 HRM2_RS03315 15562f7606c377f9e6ad89decdb89433 871 Gene3D G3DSA:3.30.460.10 60 127 6.6E-5 T 22-04-2016 HRM2_RS03315 15562f7606c377f9e6ad89decdb89433 871 PIRSF PIRSF006288 3 868 1.1E-211 T 22-04-2016 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 HRM2_RS03315 15562f7606c377f9e6ad89decdb89433 871 Pfam PF03445 Putative nucleotidyltransferase DUF294 49 113 2.1E-4 T 22-04-2016 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 HRM2_RS03315 15562f7606c377f9e6ad89decdb89433 871 Gene3D G3DSA:1.10.3210.10 421 600 1.8E-16 T 22-04-2016 IPR006674 HD domain HRM2_RS04345 c595add6179202460a5fd1b01343b008 587 Gene3D G3DSA:3.30.300.30 458 559 8.0E-26 T 22-04-2016 HRM2_RS04345 c595add6179202460a5fd1b01343b008 587 PANTHER PTHR24095:SF180 1 566 1.2E-159 T 22-04-2016 HRM2_RS04345 c595add6179202460a5fd1b01343b008 587 Gene3D G3DSA:3.40.50.980 52 214 9.9E-28 T 22-04-2016 HRM2_RS04345 c595add6179202460a5fd1b01343b008 587 Pfam PF13193 AMP-binding enzyme C-terminal domain 472 550 4.0E-18 T 22-04-2016 IPR025110 AMP-binding enzyme C-terminal domain HRM2_RS04345 c595add6179202460a5fd1b01343b008 587 Gene3D G3DSA:3.40.50.980 215 364 6.2E-27 T 22-04-2016 HRM2_RS04345 c595add6179202460a5fd1b01343b008 587 PANTHER PTHR24095 1 566 1.2E-159 T 22-04-2016 HRM2_RS04345 c595add6179202460a5fd1b01343b008 587 SUPERFAMILY SSF56801 32 560 3.01E-125 T 22-04-2016 HRM2_RS04345 c595add6179202460a5fd1b01343b008 587 Gene3D G3DSA:2.30.38.10 377 456 1.4E-11 T 22-04-2016 HRM2_RS04345 c595add6179202460a5fd1b01343b008 587 Pfam PF00501 AMP-binding enzyme 54 463 2.4E-63 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS23655 5736a84260c725889b891dfbd9a29ff8 577 Pfam PF13193 AMP-binding enzyme C-terminal domain 490 564 7.0E-18 T 22-04-2016 IPR025110 AMP-binding enzyme C-terminal domain HRM2_RS23655 5736a84260c725889b891dfbd9a29ff8 577 ProSitePatterns PS00455 Putative AMP-binding domain signature. 210 221 - T 22-04-2016 IPR020845 AMP-binding, conserved site HRM2_RS23655 5736a84260c725889b891dfbd9a29ff8 577 Gene3D G3DSA:3.40.50.980 26 215 1.4E-38 T 22-04-2016 HRM2_RS23655 5736a84260c725889b891dfbd9a29ff8 577 Gene3D G3DSA:3.40.50.980 216 393 6.9E-42 T 22-04-2016 HRM2_RS23655 5736a84260c725889b891dfbd9a29ff8 577 Pfam PF00501 AMP-binding enzyme 31 480 3.3E-111 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS23655 5736a84260c725889b891dfbd9a29ff8 577 SUPERFAMILY SSF56801 18 573 9.16E-151 T 22-04-2016 HRM2_RS23655 5736a84260c725889b891dfbd9a29ff8 577 Gene3D G3DSA:2.30.38.10 394 474 1.4E-24 T 22-04-2016 HRM2_RS23655 5736a84260c725889b891dfbd9a29ff8 577 PANTHER PTHR24096 23 575 4.3E-175 T 22-04-2016 HRM2_RS23655 5736a84260c725889b891dfbd9a29ff8 577 Gene3D G3DSA:3.30.300.30 477 575 5.9E-31 T 22-04-2016 HRM2_RS04720 c9b692e004990b598eacce98a0224096 798 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 351 488 5.6E-20 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HRM2_RS04720 c9b692e004990b598eacce98a0224096 798 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 725 743 2.1E-53 T 22-04-2016 HRM2_RS04720 c9b692e004990b598eacce98a0224096 798 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 355 374 2.1E-53 T 22-04-2016 HRM2_RS04720 c9b692e004990b598eacce98a0224096 798 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 672 691 2.1E-53 T 22-04-2016 HRM2_RS04720 c9b692e004990b598eacce98a0224096 798 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 595 611 2.1E-53 T 22-04-2016 HRM2_RS04720 c9b692e004990b598eacce98a0224096 798 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 702 721 2.1E-53 T 22-04-2016 HRM2_RS04720 c9b692e004990b598eacce98a0224096 798 SUPERFAMILY SSF88697 9 199 1.27E-8 T 22-04-2016 IPR015947 PUA-like domain HRM2_RS04720 c9b692e004990b598eacce98a0224096 798 Gene3D G3DSA:1.10.8.60 501 583 2.7E-26 T 22-04-2016 HRM2_RS04720 c9b692e004990b598eacce98a0224096 798 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 569 770 7.4E-85 T 22-04-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 HRM2_RS04720 c9b692e004990b598eacce98a0224096 798 TIGRFAM TIGR00763 lon: endopeptidase La 12 769 6.7E-250 T 22-04-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 HRM2_RS04720 c9b692e004990b598eacce98a0224096 798 SMART SM00382 347 492 5.9E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS04720 c9b692e004990b598eacce98a0224096 798 SMART SM00464 9 201 0.0022 T 22-04-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 HRM2_RS04720 c9b692e004990b598eacce98a0224096 798 PIRSF PIRSF001174 1 773 4.3E-254 T 22-04-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 HRM2_RS04720 c9b692e004990b598eacce98a0224096 798 SUPERFAMILY SSF52540 310 592 2.15E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04720 c9b692e004990b598eacce98a0224096 798 Gene3D G3DSA:3.40.50.300 307 500 2.6E-34 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04720 c9b692e004990b598eacce98a0224096 798 PANTHER PTHR10046:SF24 9 775 0.0 T 22-04-2016 HRM2_RS04720 c9b692e004990b598eacce98a0224096 798 Gene3D G3DSA:3.30.230.10 592 768 1.9E-71 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HRM2_RS04720 c9b692e004990b598eacce98a0224096 798 PANTHER PTHR10046 9 775 0.0 T 22-04-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 HRM2_RS04720 c9b692e004990b598eacce98a0224096 798 SUPERFAMILY SSF54211 595 767 2.66E-52 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS04720 c9b692e004990b598eacce98a0224096 798 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 9 199 1.5E-11 T 22-04-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 HRM2_RS00830 45619d309744238c8cbaedd28cf0285e 925 Gene3D G3DSA:3.20.20.450 669 918 8.3E-82 T 22-04-2016 IPR001633 EAL domain HRM2_RS00830 45619d309744238c8cbaedd28cf0285e 925 PANTHER PTHR33121:SF13 631 919 6.1E-71 T 22-04-2016 HRM2_RS00830 45619d309744238c8cbaedd28cf0285e 925 Pfam PF08447 PAS fold 384 464 4.4E-9 T 22-04-2016 IPR013655 PAS fold-3 GO:0005515 HRM2_RS00830 45619d309744238c8cbaedd28cf0285e 925 Pfam PF08447 PAS fold 258 344 1.2E-13 T 22-04-2016 IPR013655 PAS fold-3 GO:0005515 HRM2_RS00830 45619d309744238c8cbaedd28cf0285e 925 Pfam PF00990 Diguanylate cyclase, GGDEF domain 486 650 1.0E-43 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS00830 45619d309744238c8cbaedd28cf0285e 925 SUPERFAMILY SSF55785 246 353 1.05E-14 T 22-04-2016 IPR000014 PAS domain HRM2_RS00830 45619d309744238c8cbaedd28cf0285e 925 PANTHER PTHR33121 631 919 6.1E-71 T 22-04-2016 HRM2_RS00830 45619d309744238c8cbaedd28cf0285e 925 Pfam PF00563 EAL domain 672 905 1.1E-63 T 22-04-2016 IPR001633 EAL domain HRM2_RS00830 45619d309744238c8cbaedd28cf0285e 925 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 483 652 8.4E-43 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS00830 45619d309744238c8cbaedd28cf0285e 925 SUPERFAMILY SSF55785 364 476 1.61E-12 T 22-04-2016 IPR000014 PAS domain HRM2_RS00830 45619d309744238c8cbaedd28cf0285e 925 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 276 358 5.7E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS00830 45619d309744238c8cbaedd28cf0285e 925 SUPERFAMILY SSF141868 672 917 4.45E-78 T 22-04-2016 IPR001633 EAL domain HRM2_RS00830 45619d309744238c8cbaedd28cf0285e 925 SUPERFAMILY SSF55073 491 656 2.2E-46 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS00830 45619d309744238c8cbaedd28cf0285e 925 Gene3D G3DSA:3.30.70.270 488 659 1.4E-53 T 22-04-2016 HRM2_RS00830 45619d309744238c8cbaedd28cf0285e 925 SMART SM00052 664 910 2.3E-91 T 22-04-2016 IPR001633 EAL domain HRM2_RS00830 45619d309744238c8cbaedd28cf0285e 925 SMART SM00086 309 351 0.0017 T 22-04-2016 IPR001610 PAC motif HRM2_RS00830 45619d309744238c8cbaedd28cf0285e 925 SMART SM00086 434 475 7.7 T 22-04-2016 IPR001610 PAC motif HRM2_RS00830 45619d309744238c8cbaedd28cf0285e 925 SMART SM00267 475 654 4.3E-56 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS00830 45619d309744238c8cbaedd28cf0285e 925 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 36 106 1.7E-6 T 22-04-2016 IPR029095 NarX-like, N-terminal HRM2_RS00830 45619d309744238c8cbaedd28cf0285e 925 Gene3D G3DSA:3.30.450.20 359 483 5.2E-14 T 22-04-2016 HRM2_RS00830 45619d309744238c8cbaedd28cf0285e 925 Gene3D G3DSA:3.30.450.20 229 349 4.9E-16 T 22-04-2016 HRM2_RS07250 89eae529821a3f05265856623a246bde 292 PANTHER PTHR11092:SF0 1 292 2.6E-138 T 22-04-2016 HRM2_RS07250 89eae529821a3f05265856623a246bde 292 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 288 7.0E-104 T 22-04-2016 IPR010099 Epimerase family protein SDR39U1 HRM2_RS07250 89eae529821a3f05265856623a246bde 292 Pfam PF08338 Domain of unknown function (DUF1731) 244 291 2.9E-16 T 22-04-2016 IPR013549 Domain of unknown function DUF1731 HRM2_RS07250 89eae529821a3f05265856623a246bde 292 SUPERFAMILY SSF51735 1 290 1.5E-42 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS07250 89eae529821a3f05265856623a246bde 292 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 208 5.6E-19 T 22-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 HRM2_RS07250 89eae529821a3f05265856623a246bde 292 Gene3D G3DSA:3.40.50.720 1 239 2.5E-27 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS07250 89eae529821a3f05265856623a246bde 292 PANTHER PTHR11092 1 292 2.6E-138 T 22-04-2016 IPR010099 Epimerase family protein SDR39U1 HRM2_RS16800 b4fc75cb0cc936a76fb742202d37ffce 279 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 215 231 - T 22-04-2016 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 HRM2_RS16800 b4fc75cb0cc936a76fb742202d37ffce 279 Pfam PF01261 Xylose isomerase-like TIM barrel 24 239 1.1E-36 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain HRM2_RS16800 b4fc75cb0cc936a76fb742202d37ffce 279 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 2 277 6.5E-105 T 22-04-2016 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 HRM2_RS16800 b4fc75cb0cc936a76fb742202d37ffce 279 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 175 182 - T 22-04-2016 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 HRM2_RS16800 b4fc75cb0cc936a76fb742202d37ffce 279 Hamap MF_00152 Probable endonuclease 4 [nfo]. 2 279 43.023 T 22-04-2016 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 HRM2_RS16800 b4fc75cb0cc936a76fb742202d37ffce 279 PANTHER PTHR21445 1 279 6.4E-154 T 22-04-2016 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 HRM2_RS16800 b4fc75cb0cc936a76fb742202d37ffce 279 SUPERFAMILY SSF51658 1 277 2.09E-97 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain HRM2_RS16800 b4fc75cb0cc936a76fb742202d37ffce 279 SMART SM00518 3 279 6.7E-115 T 22-04-2016 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 HRM2_RS16800 b4fc75cb0cc936a76fb742202d37ffce 279 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 69 77 - T 22-04-2016 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 HRM2_RS16800 b4fc75cb0cc936a76fb742202d37ffce 279 Gene3D G3DSA:3.20.20.150 1 278 8.1E-116 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain HRM2_RS16800 b4fc75cb0cc936a76fb742202d37ffce 279 PANTHER PTHR21445:SF0 1 279 6.4E-154 T 22-04-2016 HRM2_RS06575 6ac9e7b37137fa81ff597d4e40423bb1 435 PANTHER PTHR30538 68 429 6.3E-151 T 22-04-2016 HRM2_RS06575 6ac9e7b37137fa81ff597d4e40423bb1 435 Gene3D G3DSA:3.20.20.70 166 402 1.8E-20 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS06575 6ac9e7b37137fa81ff597d4e40423bb1 435 PANTHER PTHR30538:SF1 68 429 6.3E-151 T 22-04-2016 HRM2_RS06575 6ac9e7b37137fa81ff597d4e40423bb1 435 Pfam PF12544 Lysine-2,3-aminomutase 373 429 7.2E-20 T 22-04-2016 IPR025895 Lysine-2,3-aminomutase, C-terminal domain HRM2_RS06575 6ac9e7b37137fa81ff597d4e40423bb1 435 PIRSF PIRSF004911 52 433 2.6E-167 T 22-04-2016 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase HRM2_RS06575 6ac9e7b37137fa81ff597d4e40423bb1 435 SUPERFAMILY SSF102114 166 411 7.46E-33 T 22-04-2016 HRM2_RS06575 6ac9e7b37137fa81ff597d4e40423bb1 435 TIGRFAM TIGR00238 TIGR00238: KamA family protein 73 394 1.7E-108 T 22-04-2016 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase HRM2_RS06575 6ac9e7b37137fa81ff597d4e40423bb1 435 Pfam PF04055 Radical SAM superfamily 183 335 3.2E-9 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS22650 0d50a79e062210192f44fe6d35980729 201 TIGRFAM TIGR03527 selenium_YedF: selenium metabolism protein YedF 5 201 4.5E-63 T 22-04-2016 IPR019870 Selenium metabolism protein YedF HRM2_RS22650 0d50a79e062210192f44fe6d35980729 201 Pfam PF01206 Sulfurtransferase TusA 3 61 7.4E-14 T 22-04-2016 IPR001455 TusA-like domain HRM2_RS22650 0d50a79e062210192f44fe6d35980729 201 PANTHER PTHR33279:SF3 5 199 1.3E-35 T 22-04-2016 HRM2_RS22650 0d50a79e062210192f44fe6d35980729 201 SUPERFAMILY SSF75169 117 199 4.24E-10 T 22-04-2016 IPR027396 DsrEFH-like HRM2_RS22650 0d50a79e062210192f44fe6d35980729 201 Pfam PF02635 DsrE/DsrF-like family 113 200 5.1E-7 T 22-04-2016 IPR003787 Sulphur relay, DsrE/F-like protein HRM2_RS22650 0d50a79e062210192f44fe6d35980729 201 SUPERFAMILY SSF64307 3 61 6.93E-11 T 22-04-2016 IPR001455 TusA-like domain HRM2_RS22650 0d50a79e062210192f44fe6d35980729 201 PANTHER PTHR33279 5 199 1.3E-35 T 22-04-2016 HRM2_RS22650 0d50a79e062210192f44fe6d35980729 201 Gene3D G3DSA:3.30.110.40 2 62 5.6E-14 T 22-04-2016 IPR001455 TusA-like domain HRM2_RS22650 0d50a79e062210192f44fe6d35980729 201 Gene3D G3DSA:3.40.1260.10 110 184 7.2E-10 T 22-04-2016 IPR027396 DsrEFH-like HRM2_RS05980 07087450abbc62b9b99149b5ce74bb0b 300 Pfam PF00892 EamA-like transporter family 23 153 1.7E-8 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS05980 07087450abbc62b9b99149b5ce74bb0b 300 Pfam PF00892 EamA-like transporter family 165 297 1.2E-11 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS05980 07087450abbc62b9b99149b5ce74bb0b 300 SUPERFAMILY SSF103481 63 157 3.27E-7 T 22-04-2016 HRM2_RS05980 07087450abbc62b9b99149b5ce74bb0b 300 SUPERFAMILY SSF103481 210 299 3.14E-10 T 22-04-2016 HRM2_RS05980 07087450abbc62b9b99149b5ce74bb0b 300 PANTHER PTHR12715 20 299 2.2E-30 T 22-04-2016 HRM2_RS21945 6c8246a435291591f9d00dd4d7608333 321 Gene3D G3DSA:3.30.420.10 176 319 2.7E-21 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS21945 6c8246a435291591f9d00dd4d7608333 321 SUPERFAMILY SSF53098 180 319 7.89E-24 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS21945 6c8246a435291591f9d00dd4d7608333 321 Pfam PF00665 Integrase core domain 178 288 7.1E-16 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 HRM2_RS13075 0dbd6e12883e6aa8819e439cb7378001 684 PANTHER PTHR10795:SF419 592 601 2.0E-65 T 22-04-2016 HRM2_RS13075 0dbd6e12883e6aa8819e439cb7378001 684 PANTHER PTHR10795:SF419 11 408 2.0E-65 T 22-04-2016 HRM2_RS13075 0dbd6e12883e6aa8819e439cb7378001 684 Gene3D G3DSA:3.40.50.200 88 390 9.8E-94 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HRM2_RS13075 0dbd6e12883e6aa8819e439cb7378001 684 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 332 342 - T 22-04-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site HRM2_RS13075 0dbd6e12883e6aa8819e439cb7378001 684 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 143 154 - T 22-04-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site HRM2_RS13075 0dbd6e12883e6aa8819e439cb7378001 684 SUPERFAMILY SSF52743 119 391 7.99E-88 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HRM2_RS13075 0dbd6e12883e6aa8819e439cb7378001 684 Gene3D G3DSA:2.60.40.1560 402 490 2.3E-4 T 22-04-2016 HRM2_RS13075 0dbd6e12883e6aa8819e439cb7378001 684 Gene3D G3DSA:2.60.40.1560 595 683 1.5E-6 T 22-04-2016 HRM2_RS13075 0dbd6e12883e6aa8819e439cb7378001 684 PANTHER PTHR10795 592 601 2.0E-65 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related HRM2_RS13075 0dbd6e12883e6aa8819e439cb7378001 684 PANTHER PTHR10795 11 408 2.0E-65 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related HRM2_RS13075 0dbd6e12883e6aa8819e439cb7378001 684 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 180 190 - T 22-04-2016 IPR022398 Peptidase S8, subtilisin, His-active site HRM2_RS13075 0dbd6e12883e6aa8819e439cb7378001 684 Pfam PF00082 Subtilase family 141 382 3.0E-39 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HRM2_RS13075 0dbd6e12883e6aa8819e439cb7378001 684 PRINTS PR00723 Subtilisin serine protease family (S8) signature 138 157 3.3E-15 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related HRM2_RS13075 0dbd6e12883e6aa8819e439cb7378001 684 PRINTS PR00723 Subtilisin serine protease family (S8) signature 331 347 3.3E-15 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related HRM2_RS13075 0dbd6e12883e6aa8819e439cb7378001 684 PRINTS PR00723 Subtilisin serine protease family (S8) signature 176 189 3.3E-15 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related HRM2_RS01470 07c072cb48bbcafc63925d4001e376c7 389 Hamap MF_00570 Nicotinate phosphoribosyltransferase [pncB]. 1 389 34.758 T 22-04-2016 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 HRM2_RS01470 07c072cb48bbcafc63925d4001e376c7 389 PANTHER PTHR11098 1 377 2.1E-151 T 22-04-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 HRM2_RS01470 07c072cb48bbcafc63925d4001e376c7 389 PIRSF PIRSF000484 1 374 1.5E-70 T 22-04-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 HRM2_RS01470 07c072cb48bbcafc63925d4001e376c7 389 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 159 380 2.7E-55 T 22-04-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 HRM2_RS01470 07c072cb48bbcafc63925d4001e376c7 389 TIGRFAM TIGR01514 NAPRTase: nicotinate phosphoribosyltransferase 1 382 3.6E-133 T 22-04-2016 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 HRM2_RS01470 07c072cb48bbcafc63925d4001e376c7 389 Gene3D G3DSA:3.20.140.10 1 372 7.1E-131 T 22-04-2016 HRM2_RS01470 07c072cb48bbcafc63925d4001e376c7 389 SUPERFAMILY SSF54675 2 134 7.06E-38 T 22-04-2016 HRM2_RS01470 07c072cb48bbcafc63925d4001e376c7 389 SUPERFAMILY SSF51690 115 383 7.65E-78 T 22-04-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 HRM2_RS01470 07c072cb48bbcafc63925d4001e376c7 389 PANTHER PTHR11098:SF12 1 377 2.1E-151 T 22-04-2016 HRM2_RS01830 d4a5d117ed1e66f133d0b400295e095a 374 Gene3D G3DSA:3.30.1330.60 266 370 3.2E-37 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS01830 d4a5d117ed1e66f133d0b400295e095a 374 PANTHER PTHR30128 239 370 2.1E-41 T 22-04-2016 HRM2_RS01830 d4a5d117ed1e66f133d0b400295e095a 374 PRINTS PR01021 OMPA domain signature 316 332 4.1E-17 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 HRM2_RS01830 d4a5d117ed1e66f133d0b400295e095a 374 PRINTS PR01021 OMPA domain signature 271 293 4.1E-17 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 HRM2_RS01830 d4a5d117ed1e66f133d0b400295e095a 374 PRINTS PR01021 OMPA domain signature 301 316 4.1E-17 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 HRM2_RS01830 d4a5d117ed1e66f133d0b400295e095a 374 SUPERFAMILY SSF103088 249 369 4.45E-37 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS01830 d4a5d117ed1e66f133d0b400295e095a 374 Pfam PF13519 von Willebrand factor type A domain 51 164 2.8E-8 T 22-04-2016 IPR002035 von Willebrand factor, type A HRM2_RS01830 d4a5d117ed1e66f133d0b400295e095a 374 Pfam PF00691 OmpA family 270 365 8.3E-25 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS01830 d4a5d117ed1e66f133d0b400295e095a 374 SUPERFAMILY SSF53300 50 222 4.08E-14 T 22-04-2016 IPR002035 von Willebrand factor, type A HRM2_RS01830 d4a5d117ed1e66f133d0b400295e095a 374 Gene3D G3DSA:3.40.50.410 51 222 2.1E-7 T 22-04-2016 IPR002035 von Willebrand factor, type A HRM2_RS01830 d4a5d117ed1e66f133d0b400295e095a 374 SMART SM00327 46 230 5.5E-5 T 22-04-2016 IPR002035 von Willebrand factor, type A HRM2_RS16910 7356ad9ea9b972ae6a284071e23824b1 541 SMART SM00283 272 540 7.8E-54 T 22-04-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HRM2_RS16910 7356ad9ea9b972ae6a284071e23824b1 541 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 332 539 4.2E-34 T 22-04-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HRM2_RS16910 7356ad9ea9b972ae6a284071e23824b1 541 Pfam PF17200 Single Cache domain 2 34 173 1.1E-20 T 22-04-2016 IPR033480 Single Cache domain 2 HRM2_RS16910 7356ad9ea9b972ae6a284071e23824b1 541 PANTHER PTHR32089 62 541 1.3E-89 T 22-04-2016 HRM2_RS16910 7356ad9ea9b972ae6a284071e23824b1 541 Gene3D G3DSA:1.10.287.950 288 497 1.0E-48 T 22-04-2016 HRM2_RS16910 7356ad9ea9b972ae6a284071e23824b1 541 SUPERFAMILY SSF58104 232 498 2.88E-56 T 22-04-2016 HRM2_RS16910 7356ad9ea9b972ae6a284071e23824b1 541 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 447 476 1.7E-22 T 22-04-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HRM2_RS16910 7356ad9ea9b972ae6a284071e23824b1 541 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 399 428 1.7E-22 T 22-04-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HRM2_RS16910 7356ad9ea9b972ae6a284071e23824b1 541 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 1 16 1.7E-22 T 22-04-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HRM2_RS16910 7356ad9ea9b972ae6a284071e23824b1 541 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 370 397 1.7E-22 T 22-04-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HRM2_RS16910 7356ad9ea9b972ae6a284071e23824b1 541 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 293 322 1.7E-22 T 22-04-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HRM2_RS16910 7356ad9ea9b972ae6a284071e23824b1 541 SMART SM01049 30 117 7.4E-8 T 22-04-2016 IPR033480 Single Cache domain 2 HRM2_RS16910 7356ad9ea9b972ae6a284071e23824b1 541 Gene3D G3DSA:3.30.450.20 20 165 8.8E-20 T 22-04-2016 HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 PANTHER PTHR24423 21 266 2.5E-178 T 22-04-2016 HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 PANTHER PTHR24423 491 883 2.5E-178 T 22-04-2016 HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 SMART SM00091 29 95 2.5E-8 T 22-04-2016 IPR000014 PAS domain HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 SMART SM00091 151 218 1.6E-5 T 22-04-2016 IPR000014 PAS domain HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 PRINTS PR00344 Bacterial sensor protein C-terminal signature 691 701 5.0E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 PRINTS PR00344 Bacterial sensor protein C-terminal signature 673 687 5.0E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 PRINTS PR00344 Bacterial sensor protein C-terminal signature 728 741 5.0E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 PRINTS PR00344 Bacterial sensor protein C-terminal signature 704 722 5.0E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 SMART SM00387 621 744 1.7E-23 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 SUPERFAMILY SSF55785 156 271 4.64E-15 T 22-04-2016 IPR000014 PAS domain HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 SMART SM00448 764 877 7.9E-21 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 Pfam PF10114 Sensory domain found in PocR 355 475 2.3E-9 T 22-04-2016 IPR018771 PocR domain UniPathway: UPA00148|UniPathway: UPA00621 HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 Pfam PF00072 Response regulator receiver domain 766 877 2.4E-18 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 SMART SM00388 514 580 0.0085 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 PANTHER PTHR24423:SF458 21 266 2.5E-178 T 22-04-2016 HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 PANTHER PTHR24423:SF458 491 883 2.5E-178 T 22-04-2016 HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 Gene3D G3DSA:3.30.450.20 154 283 6.4E-15 T 22-04-2016 HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 Gene3D G3DSA:3.30.565.10 556 745 1.1E-35 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 622 743 1.3E-15 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 SMART SM00086 101 143 8.7E-4 T 22-04-2016 IPR001610 PAC motif HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 SUPERFAMILY SSF55874 570 744 7.73E-37 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 25 149 4.3E-21 T 22-04-2016 IPR000014 PAS domain HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 153 275 1.1E-11 T 22-04-2016 IPR000014 PAS domain HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 Gene3D G3DSA:3.40.50.2300 764 882 1.2E-29 T 22-04-2016 HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 SUPERFAMILY SSF55785 16 141 1.36E-23 T 22-04-2016 IPR000014 PAS domain HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 SUPERFAMILY SSF52172 765 882 4.55E-27 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 Pfam PF13426 PAS domain 170 267 1.3E-4 T 22-04-2016 IPR000014 PAS domain HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 Pfam PF13426 PAS domain 45 141 2.0E-13 T 22-04-2016 IPR000014 PAS domain HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 Gene3D G3DSA:3.30.450.20 19 141 3.7E-23 T 22-04-2016 HRM2_RS25520 d556e834d1466b222641ed5aef720f70 884 SUPERFAMILY SSF47384 507 577 1.71E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS11475 ae75cb451391b2757dcdba2e6c6361cd 342 PRINTS PR01713 Nucleotide sugar epimerase signature 232 247 2.5E-8 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 HRM2_RS11475 ae75cb451391b2757dcdba2e6c6361cd 342 PRINTS PR01713 Nucleotide sugar epimerase signature 302 319 2.5E-8 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 HRM2_RS11475 ae75cb451391b2757dcdba2e6c6361cd 342 PRINTS PR01713 Nucleotide sugar epimerase signature 257 272 2.5E-8 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 HRM2_RS11475 ae75cb451391b2757dcdba2e6c6361cd 342 PRINTS PR01713 Nucleotide sugar epimerase signature 43 59 2.5E-8 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 HRM2_RS11475 ae75cb451391b2757dcdba2e6c6361cd 342 PANTHER PTHR10366:SF472 16 342 4.5E-123 T 22-04-2016 HRM2_RS11475 ae75cb451391b2757dcdba2e6c6361cd 342 Gene3D G3DSA:3.40.50.720 15 195 4.7E-50 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS11475 ae75cb451391b2757dcdba2e6c6361cd 342 Pfam PF01370 NAD dependent epimerase/dehydratase family 17 263 7.5E-57 T 22-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 HRM2_RS11475 ae75cb451391b2757dcdba2e6c6361cd 342 SUPERFAMILY SSF51735 17 340 1.35E-86 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS11475 ae75cb451391b2757dcdba2e6c6361cd 342 PANTHER PTHR10366 16 342 4.5E-123 T 22-04-2016 HRM2_RS11475 ae75cb451391b2757dcdba2e6c6361cd 342 Gene3D G3DSA:3.90.25.10 196 325 2.1E-32 T 22-04-2016 HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 Gene3D G3DSA:3.30.450.20 172 311 2.2E-30 T 22-04-2016 HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 Pfam PF00072 Response regulator receiver domain 830 938 1.5E-13 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 SUPERFAMILY SSF55874 641 808 1.57E-34 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 SUPERFAMILY SSF55785 194 305 2.79E-17 T 22-04-2016 IPR000014 PAS domain HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 SUPERFAMILY SSF47384 579 644 6.67E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 Pfam PF08447 PAS fold 209 298 8.0E-21 T 22-04-2016 IPR013655 PAS fold-3 GO:0005515 HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 Pfam PF08447 PAS fold 338 426 9.8E-15 T 22-04-2016 IPR013655 PAS fold-3 GO:0005515 HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 443 567 8.2E-14 T 22-04-2016 IPR000014 PAS domain HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 323 439 5.6E-10 T 22-04-2016 IPR000014 PAS domain HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 184 310 5.9E-8 T 22-04-2016 IPR000014 PAS domain HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 Gene3D G3DSA:3.30.450.20 320 442 1.4E-16 T 22-04-2016 HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 Gene3D G3DSA:3.30.450.20 443 559 1.8E-18 T 22-04-2016 HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 Gene3D G3DSA:3.40.50.2300 829 950 4.4E-21 T 22-04-2016 HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 PANTHER PTHR24423 429 913 1.4E-100 T 22-04-2016 HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 PANTHER PTHR24423 167 299 1.4E-100 T 22-04-2016 HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 Pfam PF08448 PAS fold 451 563 4.4E-15 T 22-04-2016 IPR013656 PAS fold-4 HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 689 805 6.0E-21 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 SMART SM00387 688 808 3.0E-28 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 Gene3D G3DSA:3.30.565.10 623 809 1.2E-39 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 SUPERFAMILY SSF52172 829 950 7.12E-19 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 SMART SM00091 186 254 0.21 T 22-04-2016 IPR000014 PAS domain HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 SMART SM00091 312 382 21.0 T 22-04-2016 IPR000014 PAS domain HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 SMART SM00091 445 512 210.0 T 22-04-2016 IPR000014 PAS domain HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 SMART SM00086 391 433 2.2E-6 T 22-04-2016 IPR001610 PAC motif HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 SMART SM00086 526 561 5.4 T 22-04-2016 IPR001610 PAC motif HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 SMART SM00086 261 304 2.5E-7 T 22-04-2016 IPR001610 PAC motif HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 SUPERFAMILY SSF55785 430 559 2.97E-19 T 22-04-2016 IPR000014 PAS domain HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 SMART SM00448 828 944 3.8E-11 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 PRINTS PR00344 Bacterial sensor protein C-terminal signature 768 786 7.3E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 PRINTS PR00344 Bacterial sensor protein C-terminal signature 792 805 7.3E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 PRINTS PR00344 Bacterial sensor protein C-terminal signature 727 741 7.3E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 SUPERFAMILY SSF55785 317 433 1.68E-16 T 22-04-2016 IPR000014 PAS domain HRM2_RS13595 f196b872ee6bf81f8ebf30f82ed47b32 954 SMART SM00388 583 648 5.0E-4 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 Gene3D G3DSA:3.30.2090.10 723 809 2.8E-24 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 SUPERFAMILY SSF82693 566 670 8.55E-32 T 22-04-2016 HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 Gene3D G3DSA:3.30.70.1430 38 139 3.3E-34 T 22-04-2016 HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 SUPERFAMILY SSF82714 723 809 1.26E-20 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 Gene3D G3DSA:3.30.70.1430 568 671 1.4E-35 T 22-04-2016 HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 8.5E-110 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 8.5E-110 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 8.5E-110 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 8.5E-110 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 PRINTS PR00702 Acriflavin resistance protein family signature 622 636 8.5E-110 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 8.5E-110 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 8.5E-110 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 8.5E-110 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 8.5E-110 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 PANTHER PTHR32063 1 1035 0.0 T 22-04-2016 HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 SUPERFAMILY SSF82866 296 497 5.49E-49 T 22-04-2016 HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 Pfam PF00873 AcrB/AcrD/AcrF family 1 1026 0.0 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 SUPERFAMILY SSF82693 38 132 1.36E-26 T 22-04-2016 HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 SUPERFAMILY SSF82693 136 182 3.66E-23 T 22-04-2016 HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 SUPERFAMILY SSF82693 274 330 3.66E-23 T 22-04-2016 HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 SUPERFAMILY SSF82866 838 1027 8.37E-42 T 22-04-2016 HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1039 0.0 T 22-04-2016 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 SUPERFAMILY SSF82693 673 722 2.62E-28 T 22-04-2016 HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 SUPERFAMILY SSF82693 809 857 2.62E-28 T 22-04-2016 HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 Gene3D G3DSA:3.30.2090.10 181 275 4.6E-24 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 Gene3D G3DSA:1.10.3850.10 278 498 1.4E-57 T 22-04-2016 HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 Gene3D G3DSA:1.10.3850.10 815 1028 2.1E-50 T 22-04-2016 HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 SUPERFAMILY SSF82714 183 272 3.92E-20 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS07875 85595fb3b97b3ed1f6ea4a0ef0581f54 1047 PANTHER PTHR32063:SF13 1 1035 0.0 T 22-04-2016 HRM2_RS12890 8278e906f74ff4009a0a0b86135174d5 231 Pfam PF00912 Transglycosylase 54 225 2.8E-49 T 22-04-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 HRM2_RS12890 8278e906f74ff4009a0a0b86135174d5 231 PANTHER PTHR30400:SF0 1 231 2.1E-68 T 22-04-2016 HRM2_RS12890 8278e906f74ff4009a0a0b86135174d5 231 TIGRFAM TIGR02070 mono_pep_trsgly: monofunctional biosynthetic peptidoglycan transglycosylase 10 227 8.5E-69 T 22-04-2016 IPR011812 Monofunctional biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 UniPathway: UPA00219 HRM2_RS12890 8278e906f74ff4009a0a0b86135174d5 231 Gene3D G3DSA:1.10.3810.10 62 227 2.7E-54 T 22-04-2016 HRM2_RS12890 8278e906f74ff4009a0a0b86135174d5 231 SUPERFAMILY SSF53955 60 229 1.55E-54 T 22-04-2016 IPR023346 Lysozyme-like domain HRM2_RS12890 8278e906f74ff4009a0a0b86135174d5 231 PANTHER PTHR30400 1 231 2.1E-68 T 22-04-2016 HRM2_RS11015 6d8bee0f1bfa3fc6a9525c7b37de9bb2 341 SMART SM00448 9 129 3.7E-10 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS11015 6d8bee0f1bfa3fc6a9525c7b37de9bb2 341 Pfam PF00072 Response regulator receiver domain 11 128 3.1E-15 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS11015 6d8bee0f1bfa3fc6a9525c7b37de9bb2 341 SUPERFAMILY SSF55073 183 333 1.18E-44 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS11015 6d8bee0f1bfa3fc6a9525c7b37de9bb2 341 PANTHER PTHR10799 7 121 3.7E-28 T 22-04-2016 HRM2_RS11015 6d8bee0f1bfa3fc6a9525c7b37de9bb2 341 PANTHER PTHR10799 211 332 3.7E-28 T 22-04-2016 HRM2_RS11015 6d8bee0f1bfa3fc6a9525c7b37de9bb2 341 SUPERFAMILY SSF52172 11 155 1.22E-20 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS11015 6d8bee0f1bfa3fc6a9525c7b37de9bb2 341 SMART SM00267 167 335 7.1E-59 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS11015 6d8bee0f1bfa3fc6a9525c7b37de9bb2 341 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 174 333 3.5E-49 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS11015 6d8bee0f1bfa3fc6a9525c7b37de9bb2 341 Gene3D G3DSA:3.40.50.2300 10 147 1.5E-22 T 22-04-2016 HRM2_RS11015 6d8bee0f1bfa3fc6a9525c7b37de9bb2 341 PANTHER PTHR10799:SF750 7 121 3.7E-28 T 22-04-2016 HRM2_RS11015 6d8bee0f1bfa3fc6a9525c7b37de9bb2 341 PANTHER PTHR10799:SF750 211 332 3.7E-28 T 22-04-2016 HRM2_RS11015 6d8bee0f1bfa3fc6a9525c7b37de9bb2 341 Gene3D G3DSA:3.30.70.270 180 334 6.4E-48 T 22-04-2016 HRM2_RS11015 6d8bee0f1bfa3fc6a9525c7b37de9bb2 341 Pfam PF00990 Diguanylate cyclase, GGDEF domain 178 331 2.0E-43 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS23705 79d0ef3414fd8f7fd1ce3d8996ba9d8a 531 Gene3D G3DSA:3.30.70.1450 197 262 1.8E-4 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS23705 79d0ef3414fd8f7fd1ce3d8996ba9d8a 531 Pfam PF06826 Predicted Permease Membrane Region 359 528 6.6E-36 T 22-04-2016 IPR006512 YidE/YbjL duplication HRM2_RS23705 79d0ef3414fd8f7fd1ce3d8996ba9d8a 531 Pfam PF06826 Predicted Permease Membrane Region 11 162 9.5E-30 T 22-04-2016 IPR006512 YidE/YbjL duplication HRM2_RS23705 79d0ef3414fd8f7fd1ce3d8996ba9d8a 531 Gene3D G3DSA:3.30.70.1450 279 346 4.1E-9 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS23705 79d0ef3414fd8f7fd1ce3d8996ba9d8a 531 SUPERFAMILY SSF116726 275 346 4.58E-11 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS23705 79d0ef3414fd8f7fd1ce3d8996ba9d8a 531 PANTHER PTHR30445:SF1 1 531 5.6E-141 T 22-04-2016 HRM2_RS23705 79d0ef3414fd8f7fd1ce3d8996ba9d8a 531 Pfam PF02080 TrkA-C domain 279 345 5.7E-10 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS23705 79d0ef3414fd8f7fd1ce3d8996ba9d8a 531 Pfam PF02080 TrkA-C domain 195 259 8.4E-9 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS23705 79d0ef3414fd8f7fd1ce3d8996ba9d8a 531 SUPERFAMILY SSF116726 187 261 5.89E-7 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS23705 79d0ef3414fd8f7fd1ce3d8996ba9d8a 531 PANTHER PTHR30445 1 531 5.6E-141 T 22-04-2016 HRM2_RS23705 79d0ef3414fd8f7fd1ce3d8996ba9d8a 531 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 366 515 6.2E-32 T 22-04-2016 IPR006512 YidE/YbjL duplication HRM2_RS00080 567d2f16d5293ce7d78b431590b77566 204 Gene3D G3DSA:3.40.50.10230 2 203 3.7E-83 T 22-04-2016 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 HRM2_RS00080 567d2f16d5293ce7d78b431590b77566 204 PANTHER PTHR32439:SF1 1 204 7.2E-71 T 22-04-2016 HRM2_RS00080 567d2f16d5293ce7d78b431590b77566 204 SUPERFAMILY SSF63965 5 202 8.89E-72 T 22-04-2016 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 HRM2_RS00080 567d2f16d5293ce7d78b431590b77566 204 PANTHER PTHR32439 1 204 7.2E-71 T 22-04-2016 HRM2_RS00080 567d2f16d5293ce7d78b431590b77566 204 Pfam PF02570 Precorrin-8X methylmutase 5 198 2.8E-80 T 22-04-2016 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 HRM2_RS16555 d27fc7333f2c5f31f76b187c545f9527 257 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 70 228 1.9E-6 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS16555 d27fc7333f2c5f31f76b187c545f9527 257 PANTHER PTHR30151 1 256 9.2E-13 T 22-04-2016 HRM2_RS16555 d27fc7333f2c5f31f76b187c545f9527 257 SUPERFAMILY SSF161098 52 230 1.31E-11 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS10950 50e8bf9418911eae86585ba378a41298 59 Gene3D G3DSA:3.50.50.60 9 57 7.5E-17 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS10950 50e8bf9418911eae86585ba378a41298 59 PRINTS PR00419 Adrenodoxin reductase family signature 31 44 7.0E-5 T 22-04-2016 HRM2_RS10950 50e8bf9418911eae86585ba378a41298 59 PRINTS PR00419 Adrenodoxin reductase family signature 8 30 7.0E-5 T 22-04-2016 HRM2_RS10950 50e8bf9418911eae86585ba378a41298 59 Pfam PF13450 NAD(P)-binding Rossmann-like domain 11 47 6.9E-9 T 22-04-2016 HRM2_RS10950 50e8bf9418911eae86585ba378a41298 59 SUPERFAMILY SSF51971 9 56 2.47E-12 T 22-04-2016 HRM2_RS10950 50e8bf9418911eae86585ba378a41298 59 PANTHER PTHR10742:SF263 8 59 1.2E-22 T 22-04-2016 HRM2_RS10950 50e8bf9418911eae86585ba378a41298 59 PANTHER PTHR10742 8 59 1.2E-22 T 22-04-2016 HRM2_RS20710 0b19257bc37aca39ef34e1129ec4afaa 456 Pfam PF00158 Sigma-54 interaction domain 141 308 3.6E-70 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS20710 0b19257bc37aca39ef34e1129ec4afaa 456 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 354 363 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS20710 0b19257bc37aca39ef34e1129ec4afaa 456 Gene3D G3DSA:3.40.50.300 138 313 1.1E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20710 0b19257bc37aca39ef34e1129ec4afaa 456 Pfam PF02954 Bacterial regulatory protein, Fis family 413 440 2.0E-10 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS20710 0b19257bc37aca39ef34e1129ec4afaa 456 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 227 242 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS20710 0b19257bc37aca39ef34e1129ec4afaa 456 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 428 448 1.3E-8 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS20710 0b19257bc37aca39ef34e1129ec4afaa 456 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 411 428 1.3E-8 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS20710 0b19257bc37aca39ef34e1129ec4afaa 456 Gene3D G3DSA:1.10.8.60 314 391 3.5E-25 T 22-04-2016 HRM2_RS20710 0b19257bc37aca39ef34e1129ec4afaa 456 Pfam PF13426 PAS domain 23 124 2.3E-12 T 22-04-2016 IPR000014 PAS domain HRM2_RS20710 0b19257bc37aca39ef34e1129ec4afaa 456 SMART SM00091 12 78 1.8E-4 T 22-04-2016 IPR000014 PAS domain HRM2_RS20710 0b19257bc37aca39ef34e1129ec4afaa 456 SUPERFAMILY SSF52540 140 383 4.46E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20710 0b19257bc37aca39ef34e1129ec4afaa 456 SMART SM00382 161 304 2.2E-5 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS20710 0b19257bc37aca39ef34e1129ec4afaa 456 Gene3D G3DSA:1.10.10.60 410 444 2.9E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS20710 0b19257bc37aca39ef34e1129ec4afaa 456 SUPERFAMILY SSF55785 12 123 5.76E-15 T 22-04-2016 IPR000014 PAS domain HRM2_RS20710 0b19257bc37aca39ef34e1129ec4afaa 456 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 12 129 9.9E-13 T 22-04-2016 IPR000014 PAS domain HRM2_RS20710 0b19257bc37aca39ef34e1129ec4afaa 456 PANTHER PTHR32071 122 444 8.5E-149 T 22-04-2016 HRM2_RS20710 0b19257bc37aca39ef34e1129ec4afaa 456 Gene3D G3DSA:3.30.450.20 12 123 3.2E-17 T 22-04-2016 HRM2_RS20710 0b19257bc37aca39ef34e1129ec4afaa 456 SUPERFAMILY SSF46689 354 444 3.58E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS03090 554e5d0cb621d366cb51cc23e2d581e9 163 Pfam PF00582 Universal stress protein family 3 152 1.0E-9 T 22-04-2016 IPR006016 UspA GO:0006950 HRM2_RS03090 554e5d0cb621d366cb51cc23e2d581e9 163 PRINTS PR01438 Universal stress protein signature 3 21 8.4E-8 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS03090 554e5d0cb621d366cb51cc23e2d581e9 163 PRINTS PR01438 Universal stress protein signature 122 134 8.4E-8 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS03090 554e5d0cb621d366cb51cc23e2d581e9 163 PRINTS PR01438 Universal stress protein signature 140 162 8.4E-8 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS03090 554e5d0cb621d366cb51cc23e2d581e9 163 Gene3D G3DSA:3.40.50.620 3 152 4.8E-18 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS03090 554e5d0cb621d366cb51cc23e2d581e9 163 SUPERFAMILY SSF52402 1 152 1.26E-13 T 22-04-2016 HRM2_RS21585 9f8036ac70de035f6c1745755d608335 576 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 230 357 1.1E-28 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 HRM2_RS21585 9f8036ac70de035f6c1745755d608335 576 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 92 187 1.6E-18 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 HRM2_RS21585 9f8036ac70de035f6c1745755d608335 576 Pfam PF13246 Cation transport ATPase (P-type) 377 460 3.3E-18 T 22-04-2016 HRM2_RS21585 9f8036ac70de035f6c1745755d608335 576 Gene3D G3DSA:3.40.1110.10 336 526 6.2E-59 T 22-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 HRM2_RS21585 9f8036ac70de035f6c1745755d608335 576 SMART SM00831 11 85 3.6E-23 T 22-04-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal HRM2_RS21585 9f8036ac70de035f6c1745755d608335 576 SUPERFAMILY SSF56784 522 557 3.23E-9 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS21585 9f8036ac70de035f6c1745755d608335 576 SUPERFAMILY SSF56784 331 343 3.23E-9 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS21585 9f8036ac70de035f6c1745755d608335 576 SUPERFAMILY SSF81653 124 232 1.15E-29 T 22-04-2016 HRM2_RS21585 9f8036ac70de035f6c1745755d608335 576 SUPERFAMILY SSF81660 339 532 1.02E-50 T 22-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 HRM2_RS21585 9f8036ac70de035f6c1745755d608335 576 Pfam PF00122 E1-E2 ATPase 91 324 2.8E-64 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HRM2_RS21585 9f8036ac70de035f6c1745755d608335 576 Gene3D G3DSA:2.70.150.10 21 64 3.2E-37 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HRM2_RS21585 9f8036ac70de035f6c1745755d608335 576 Gene3D G3DSA:2.70.150.10 118 233 3.2E-37 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HRM2_RS21585 9f8036ac70de035f6c1745755d608335 576 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 326 347 2.1E-10 T 22-04-2016 HRM2_RS21585 9f8036ac70de035f6c1745755d608335 576 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 86 106 2.1E-10 T 22-04-2016 HRM2_RS21585 9f8036ac70de035f6c1745755d608335 576 Pfam PF00690 Cation transporter/ATPase, N-terminus 13 80 7.5E-17 T 22-04-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal HRM2_RS21585 9f8036ac70de035f6c1745755d608335 576 SUPERFAMILY SSF81665 234 327 3.66E-64 T 22-04-2016 HRM2_RS21585 9f8036ac70de035f6c1745755d608335 576 SUPERFAMILY SSF81665 12 123 3.66E-64 T 22-04-2016 HRM2_RS21585 9f8036ac70de035f6c1745755d608335 576 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 542 552 9.4E-23 T 22-04-2016 HRM2_RS21585 9f8036ac70de035f6c1745755d608335 576 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 333 347 9.4E-23 T 22-04-2016 HRM2_RS21585 9f8036ac70de035f6c1745755d608335 576 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 170 184 9.4E-23 T 22-04-2016 HRM2_RS21585 9f8036ac70de035f6c1745755d608335 576 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 520 531 9.4E-23 T 22-04-2016 HRM2_RS21585 9f8036ac70de035f6c1745755d608335 576 Gene3D G3DSA:3.40.50.1000 527 556 4.7E-13 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS21585 9f8036ac70de035f6c1745755d608335 576 Gene3D G3DSA:3.40.50.1000 317 335 4.7E-13 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS21585 9f8036ac70de035f6c1745755d608335 576 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 335 341 - T 22-04-2016 IPR018303 P-type ATPase, phosphorylation site HRM2_RS21585 9f8036ac70de035f6c1745755d608335 576 PANTHER PTHR24093 13 552 2.9E-192 T 22-04-2016 HRM2_RS21585 9f8036ac70de035f6c1745755d608335 576 Gene3D G3DSA:1.20.1110.10 65 117 2.6E-15 T 22-04-2016 IPR023298 P-type ATPase, transmembrane domain HRM2_RS22415 c330f1fbe0ad02529eb4e9654cf48fdd 355 Gene3D G3DSA:3.40.190.10 137 276 1.8E-15 T 22-04-2016 HRM2_RS22415 c330f1fbe0ad02529eb4e9654cf48fdd 355 SUPERFAMILY SSF53850 25 346 2.97E-63 T 22-04-2016 HRM2_RS22415 c330f1fbe0ad02529eb4e9654cf48fdd 355 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 254 273 6.9E-17 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS22415 c330f1fbe0ad02529eb4e9654cf48fdd 355 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 73 87 6.9E-17 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS22415 c330f1fbe0ad02529eb4e9654cf48fdd 355 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 46 67 6.9E-17 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS22415 c330f1fbe0ad02529eb4e9654cf48fdd 355 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 124 140 6.9E-17 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS22415 c330f1fbe0ad02529eb4e9654cf48fdd 355 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 30 46 6.9E-17 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS22415 c330f1fbe0ad02529eb4e9654cf48fdd 355 Pfam PF13416 Bacterial extracellular solute-binding protein 40 306 1.8E-27 T 22-04-2016 HRM2_RS22415 c330f1fbe0ad02529eb4e9654cf48fdd 355 PANTHER PTHR30222 9 352 1.3E-55 T 22-04-2016 HRM2_RS22415 c330f1fbe0ad02529eb4e9654cf48fdd 355 Gene3D G3DSA:3.40.190.10 24 133 4.7E-35 T 22-04-2016 HRM2_RS22415 c330f1fbe0ad02529eb4e9654cf48fdd 355 Gene3D G3DSA:3.40.190.10 277 318 4.7E-35 T 22-04-2016 HRM2_RS22415 c330f1fbe0ad02529eb4e9654cf48fdd 355 PANTHER PTHR30222:SF5 9 352 1.3E-55 T 22-04-2016 HRM2_RS08395 478e480a6b10446c87eb346685b52e9d 527 PANTHER PTHR11615:SF162 1 525 9.9E-161 T 22-04-2016 HRM2_RS08395 478e480a6b10446c87eb346685b52e9d 527 SUPERFAMILY SSF53706 1 416 9.29E-147 T 22-04-2016 HRM2_RS08395 478e480a6b10446c87eb346685b52e9d 527 Pfam PF00384 Molybdopterin oxidoreductase 1 331 4.5E-80 T 22-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 HRM2_RS08395 478e480a6b10446c87eb346685b52e9d 527 PANTHER PTHR11615 1 525 9.9E-161 T 22-04-2016 HRM2_RS08395 478e480a6b10446c87eb346685b52e9d 527 Pfam PF01568 Molydopterin dinucleotide binding domain 414 520 2.3E-29 T 22-04-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 HRM2_RS08395 478e480a6b10446c87eb346685b52e9d 527 Gene3D G3DSA:3.40.50.740 222 353 2.2E-57 T 22-04-2016 HRM2_RS08395 478e480a6b10446c87eb346685b52e9d 527 Gene3D G3DSA:2.40.40.20 368 526 8.0E-49 T 22-04-2016 HRM2_RS08395 478e480a6b10446c87eb346685b52e9d 527 Gene3D G3DSA:3.40.228.10 1 202 3.9E-74 T 22-04-2016 HRM2_RS08395 478e480a6b10446c87eb346685b52e9d 527 SUPERFAMILY SSF50692 370 526 1.79E-43 T 22-04-2016 IPR009010 Aspartate decarboxylase-like domain HRM2_RS01215 0229343e15ff15eb0d9f588555759b21 373 SUPERFAMILY SSF52172 8 141 2.7E-40 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS01215 0229343e15ff15eb0d9f588555759b21 373 SUPERFAMILY SSF81606 172 372 1.15E-6 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 HRM2_RS01215 0229343e15ff15eb0d9f588555759b21 373 SMART SM00448 7 120 2.3E-39 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS01215 0229343e15ff15eb0d9f588555759b21 373 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 186 373 4.2E-33 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 HRM2_RS01215 0229343e15ff15eb0d9f588555759b21 373 PANTHER PTHR26402:SF495 7 372 6.1E-46 T 22-04-2016 HRM2_RS01215 0229343e15ff15eb0d9f588555759b21 373 SMART SM00331 158 373 8.6E-22 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 HRM2_RS01215 0229343e15ff15eb0d9f588555759b21 373 PANTHER PTHR26402 7 372 6.1E-46 T 22-04-2016 HRM2_RS01215 0229343e15ff15eb0d9f588555759b21 373 Pfam PF00072 Response regulator receiver domain 9 120 1.0E-25 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS01215 0229343e15ff15eb0d9f588555759b21 373 Gene3D G3DSA:3.40.50.2300 7 126 3.4E-39 T 22-04-2016 HRM2_RS17685 ef9afe35cb055e143c48f0f625bb8245 239 Gene3D G3DSA:3.20.20.70 1 237 5.3E-97 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS17685 ef9afe35cb055e143c48f0f625bb8245 239 PANTHER PTHR30456 1 238 3.2E-115 T 22-04-2016 HRM2_RS17685 ef9afe35cb055e143c48f0f625bb8245 239 SUPERFAMILY SSF63892 1 237 1.09E-89 T 22-04-2016 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2|UniPathway: UPA00244 HRM2_RS17685 ef9afe35cb055e143c48f0f625bb8245 239 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 239 110.276 T 22-04-2016 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2|UniPathway: UPA00244 HRM2_RS17685 ef9afe35cb055e143c48f0f625bb8245 239 PANTHER PTHR30456:SF0 1 238 3.2E-115 T 22-04-2016 HRM2_RS17685 ef9afe35cb055e143c48f0f625bb8245 239 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 3 236 2.9E-93 T 22-04-2016 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2|UniPathway: UPA00244 HRM2_RS17685 ef9afe35cb055e143c48f0f625bb8245 239 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 3 237 2.7E-83 T 22-04-2016 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2|UniPathway: UPA00244 HRM2_RS18665 496ca12f04451ef274645192cf069a40 892 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 155 292 4.6E-58 T 22-04-2016 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain HRM2_RS18665 496ca12f04451ef274645192cf069a40 892 SUPERFAMILY SSF55729 728 874 2.7E-22 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS18665 496ca12f04451ef274645192cf069a40 892 Gene3D G3DSA:3.40.630.30 725 876 1.2E-22 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS18665 496ca12f04451ef274645192cf069a40 892 Pfam PF13380 CoA binding domain 14 139 2.6E-22 T 22-04-2016 IPR003781 CoA-binding GO:0048037 HRM2_RS18665 496ca12f04451ef274645192cf069a40 892 Gene3D G3DSA:3.40.50.261 298 447 2.4E-20 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS18665 496ca12f04451ef274645192cf069a40 892 PANTHER PTHR11117:SF8 8 707 1.3E-277 T 22-04-2016 HRM2_RS18665 496ca12f04451ef274645192cf069a40 892 Gene3D G3DSA:3.40.50.261 136 290 2.7E-35 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS18665 496ca12f04451ef274645192cf069a40 892 SMART SM00881 9 104 1.2E-26 T 22-04-2016 IPR003781 CoA-binding GO:0048037 HRM2_RS18665 496ca12f04451ef274645192cf069a40 892 Pfam PF13302 Acetyltransferase (GNAT) domain 733 872 3.4E-9 T 22-04-2016 IPR000182 GNAT domain GO:0008080 HRM2_RS18665 496ca12f04451ef274645192cf069a40 892 SUPERFAMILY SSF52210 133 299 1.28E-48 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS18665 496ca12f04451ef274645192cf069a40 892 Gene3D G3DSA:3.40.50.720 5 135 3.2E-36 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS18665 496ca12f04451ef274645192cf069a40 892 SUPERFAMILY SSF56059 488 702 2.78E-35 T 22-04-2016 HRM2_RS18665 496ca12f04451ef274645192cf069a40 892 SUPERFAMILY SSF51735 3 143 6.03E-33 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS18665 496ca12f04451ef274645192cf069a40 892 Pfam PF13549 ATP-grasp domain 482 702 5.8E-75 T 22-04-2016 HRM2_RS18665 496ca12f04451ef274645192cf069a40 892 PANTHER PTHR11117 8 707 1.3E-277 T 22-04-2016 HRM2_RS18665 496ca12f04451ef274645192cf069a40 892 SUPERFAMILY SSF52210 298 454 1.05E-41 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS05515 31f8aaca55abc148830e397bb93ceba6 742 PANTHER PTHR24423:SF471 16 26 3.5E-113 T 22-04-2016 HRM2_RS05515 31f8aaca55abc148830e397bb93ceba6 742 PANTHER PTHR24423:SF471 404 741 3.5E-113 T 22-04-2016 HRM2_RS05515 31f8aaca55abc148830e397bb93ceba6 742 Gene3D G3DSA:3.30.450.20 401 517 1.8E-12 T 22-04-2016 HRM2_RS05515 31f8aaca55abc148830e397bb93ceba6 742 Pfam PF00672 HAMP domain 314 380 7.5E-14 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS05515 31f8aaca55abc148830e397bb93ceba6 742 Pfam PF00512 His Kinase A (phospho-acceptor) domain 529 592 4.7E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS05515 31f8aaca55abc148830e397bb93ceba6 742 PRINTS PR00344 Bacterial sensor protein C-terminal signature 704 722 1.8E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS05515 31f8aaca55abc148830e397bb93ceba6 742 PRINTS PR00344 Bacterial sensor protein C-terminal signature 693 703 1.8E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS05515 31f8aaca55abc148830e397bb93ceba6 742 PRINTS PR00344 Bacterial sensor protein C-terminal signature 728 741 1.8E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS05515 31f8aaca55abc148830e397bb93ceba6 742 PRINTS PR00344 Bacterial sensor protein C-terminal signature 675 689 1.8E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS05515 31f8aaca55abc148830e397bb93ceba6 742 Gene3D G3DSA:3.30.565.10 597 741 1.1E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS05515 31f8aaca55abc148830e397bb93ceba6 742 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 411 524 1.3E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS05515 31f8aaca55abc148830e397bb93ceba6 742 SUPERFAMILY SSF55874 587 741 1.02E-32 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS05515 31f8aaca55abc148830e397bb93ceba6 742 Gene3D G3DSA:1.10.287.130 522 592 7.6E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS05515 31f8aaca55abc148830e397bb93ceba6 742 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 637 741 1.8E-16 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS05515 31f8aaca55abc148830e397bb93ceba6 742 SUPERFAMILY SSF158472 334 380 2.62E-9 T 22-04-2016 HRM2_RS05515 31f8aaca55abc148830e397bb93ceba6 742 SMART SM00091 406 471 1.5E-4 T 22-04-2016 IPR000014 PAS domain HRM2_RS05515 31f8aaca55abc148830e397bb93ceba6 742 Pfam PF13426 PAS domain 418 518 2.9E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS05515 31f8aaca55abc148830e397bb93ceba6 742 SUPERFAMILY SSF55785 404 512 2.47E-10 T 22-04-2016 IPR000014 PAS domain HRM2_RS05515 31f8aaca55abc148830e397bb93ceba6 742 PIRSF PIRSF037532 3 742 2.4E-195 T 22-04-2016 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator HRM2_RS05515 31f8aaca55abc148830e397bb93ceba6 742 PANTHER PTHR24423 16 26 3.5E-113 T 22-04-2016 HRM2_RS05515 31f8aaca55abc148830e397bb93ceba6 742 PANTHER PTHR24423 404 741 3.5E-113 T 22-04-2016 HRM2_RS05515 31f8aaca55abc148830e397bb93ceba6 742 SMART SM00387 636 742 2.5E-25 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS05515 31f8aaca55abc148830e397bb93ceba6 742 SMART SM00304 333 385 2.7E-6 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS05515 31f8aaca55abc148830e397bb93ceba6 742 SUPERFAMILY SSF47384 521 594 3.73E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS05515 31f8aaca55abc148830e397bb93ceba6 742 SMART SM00388 527 596 5.9E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS02965 04031da0ac4a7574e3e334956cd382e1 274 Pfam PF02219 Methylenetetrahydrofolate reductase 9 234 2.0E-22 T 22-04-2016 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 HRM2_RS02965 04031da0ac4a7574e3e334956cd382e1 274 SUPERFAMILY SSF51730 7 272 4.32E-45 T 22-04-2016 IPR029041 FAD-linked oxidoreductase-like HRM2_RS02965 04031da0ac4a7574e3e334956cd382e1 274 Gene3D G3DSA:3.20.20.220 7 273 2.3E-41 T 22-04-2016 IPR029041 FAD-linked oxidoreductase-like HRM2_RS00500 0fc86ef9102ec353717097c640fe22a9 479 PANTHER PTHR30535:SF13 120 474 1.8E-46 T 22-04-2016 HRM2_RS00500 0fc86ef9102ec353717097c640fe22a9 479 SMART SM00900 16 92 8.8E-18 T 22-04-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 HRM2_RS00500 0fc86ef9102ec353717097c640fe22a9 479 Pfam PF04205 FMN-binding domain 16 90 3.1E-15 T 22-04-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 HRM2_RS00500 0fc86ef9102ec353717097c640fe22a9 479 SUPERFAMILY SSF53807 129 443 5.49E-40 T 22-04-2016 HRM2_RS00500 0fc86ef9102ec353717097c640fe22a9 479 Gene3D G3DSA:3.40.50.1980 127 274 2.0E-10 T 22-04-2016 HRM2_RS00500 0fc86ef9102ec353717097c640fe22a9 479 Gene3D G3DSA:3.40.50.1980 277 451 4.2E-23 T 22-04-2016 HRM2_RS00500 0fc86ef9102ec353717097c640fe22a9 479 PANTHER PTHR30535 120 474 1.8E-46 T 22-04-2016 HRM2_RS00500 0fc86ef9102ec353717097c640fe22a9 479 Pfam PF01497 Periplasmic binding protein 210 418 1.0E-25 T 22-04-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 HRM2_RS21415 386fe3391df2b88091b62ae8e860a849 626 PANTHER PTHR30109:SF4 9 626 7.1E-257 T 22-04-2016 HRM2_RS21415 386fe3391df2b88091b62ae8e860a849 626 PIRSF PIRSF005023 1 626 2.8E-258 T 22-04-2016 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.99.2|KEGG: 00680+1.2.99.2|KEGG: 00720+1.2.99.2|MetaCyc: PWY-5372|MetaCyc: PWY-6780 HRM2_RS21415 386fe3391df2b88091b62ae8e860a849 626 Pfam PF03063 Prismane/CO dehydrogenase family 50 606 1.6E-172 T 22-04-2016 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS21415 386fe3391df2b88091b62ae8e860a849 626 TIGRFAM TIGR01702 CO_DH_cata: carbon-monoxide dehydrogenase, catalytic subunit 11 626 1.4E-222 T 22-04-2016 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.99.2|KEGG: 00680+1.2.99.2|KEGG: 00720+1.2.99.2|MetaCyc: PWY-5372|MetaCyc: PWY-6780 HRM2_RS21415 386fe3391df2b88091b62ae8e860a849 626 Gene3D G3DSA:3.40.50.2030 412 626 1.9E-87 T 22-04-2016 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS21415 386fe3391df2b88091b62ae8e860a849 626 SUPERFAMILY SSF56821 8 626 1.18E-205 T 22-04-2016 IPR011254 Prismane-like GO:0003824|GO:0016491|GO:0055114 HRM2_RS21415 386fe3391df2b88091b62ae8e860a849 626 Gene3D G3DSA:3.40.50.2030 243 411 6.2E-71 T 22-04-2016 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS21415 386fe3391df2b88091b62ae8e860a849 626 Gene3D G3DSA:1.20.1270.30 68 241 4.5E-73 T 22-04-2016 IPR016101 CO dehydrogenase, alpha-bundle GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.99.2|KEGG: 00680+1.2.99.2|KEGG: 00720+1.2.99.2|MetaCyc: PWY-5372|MetaCyc: PWY-6780 HRM2_RS21415 386fe3391df2b88091b62ae8e860a849 626 PANTHER PTHR30109 9 626 7.1E-257 T 22-04-2016 HRM2_RS23235 d94e913c30a8f265980addca0ebf9730 167 SUPERFAMILY SSF57802 134 166 7.74E-10 T 22-04-2016 HRM2_RS23235 d94e913c30a8f265980addca0ebf9730 167 Pfam PF02915 Rubrerythrin 7 123 1.2E-13 T 22-04-2016 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 HRM2_RS23235 d94e913c30a8f265980addca0ebf9730 167 PANTHER PTHR33746 1 167 2.1E-39 T 22-04-2016 HRM2_RS23235 d94e913c30a8f265980addca0ebf9730 167 SUPERFAMILY SSF47240 1 124 4.8E-25 T 22-04-2016 IPR009078 Ferritin-like superfamily HRM2_RS23235 d94e913c30a8f265980addca0ebf9730 167 Gene3D G3DSA:1.20.1260.10 2 126 6.8E-29 T 22-04-2016 IPR012347 Ferritin-related HRM2_RS23235 d94e913c30a8f265980addca0ebf9730 167 PANTHER PTHR33746:SF3 1 167 2.1E-39 T 22-04-2016 HRM2_RS23235 d94e913c30a8f265980addca0ebf9730 167 Gene3D G3DSA:2.20.28.10 133 165 1.1E-11 T 22-04-2016 IPR004039 Rubredoxin-type fold HRM2_RS03755 fbdfa0d68ebde33dd08fd080d800496e 318 SUPERFAMILY SSF53800 29 317 2.51E-63 T 22-04-2016 HRM2_RS03755 fbdfa0d68ebde33dd08fd080d800496e 318 Gene3D G3DSA:3.40.50.1400 213 305 8.8E-23 T 22-04-2016 HRM2_RS03755 fbdfa0d68ebde33dd08fd080d800496e 318 Gene3D G3DSA:3.40.50.1400 24 209 2.9E-33 T 22-04-2016 HRM2_RS03755 fbdfa0d68ebde33dd08fd080d800496e 318 Pfam PF06180 Cobalt chelatase (CbiK) 30 316 6.1E-82 T 22-04-2016 IPR010388 Anaerobic cobalt chelatase GO:0016852|GO:0019251 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 HRM2_RS03755 fbdfa0d68ebde33dd08fd080d800496e 318 PIRSF PIRSF033579 28 318 2.9E-84 T 22-04-2016 IPR010388 Anaerobic cobalt chelatase GO:0016852|GO:0019251 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 SUPERFAMILY SSF52374 4 226 2.7E-149 T 22-04-2016 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 SUPERFAMILY SSF52374 420 667 2.7E-149 T 22-04-2016 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 Gene3D G3DSA:3.40.50.620 617 646 1.3E-153 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 Gene3D G3DSA:3.40.50.620 429 581 1.3E-153 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 Gene3D G3DSA:3.40.50.620 3 222 1.3E-153 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 PANTHER PTHR11946:SF7 240 265 0.0 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 PANTHER PTHR11946:SF7 476 582 0.0 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 PANTHER PTHR11946:SF7 617 863 0.0 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 PANTHER PTHR11946:SF7 289 460 0.0 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 PANTHER PTHR11946:SF7 1 206 0.0 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 Gene3D G3DSA:3.90.740.10 223 428 1.0E-55 T 22-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 SUPERFAMILY SSF47323 661 863 1.79E-36 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 5 863 0.0 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 PANTHER PTHR11946 240 265 0.0 T 22-04-2016 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 PANTHER PTHR11946 476 582 0.0 T 22-04-2016 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 PANTHER PTHR11946 617 863 0.0 T 22-04-2016 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 PANTHER PTHR11946 289 460 0.0 T 22-04-2016 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 PANTHER PTHR11946 1 206 0.0 T 22-04-2016 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 PRINTS PR00985 Leucyl-tRNA synthetase signature 493 511 5.5E-49 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 PRINTS PR00985 Leucyl-tRNA synthetase signature 565 575 5.5E-49 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 PRINTS PR00985 Leucyl-tRNA synthetase signature 153 169 5.5E-49 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 PRINTS PR00985 Leucyl-tRNA synthetase signature 532 554 5.5E-49 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 PRINTS PR00985 Leucyl-tRNA synthetase signature 215 234 5.5E-49 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 PRINTS PR00985 Leucyl-tRNA synthetase signature 185 198 5.5E-49 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 PRINTS PR00985 Leucyl-tRNA synthetase signature 127 144 5.5E-49 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 SUPERFAMILY SSF50677 226 418 1.57E-51 T 22-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 4 863 22.819 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 Gene3D G3DSA:1.10.730.10 647 799 2.0E-44 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 Pfam PF09334 tRNA synthetases class I (M) 41 183 8.5E-22 T 22-04-2016 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 422 579 7.6E-8 T 22-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 618 657 1.7E-7 T 22-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 Pfam PF08264 Anticodon-binding domain of tRNA 705 821 3.7E-22 T 22-04-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 HRM2_RS13465 7a2401e2215a254af7c89bb236169779 863 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 221 408 9.2E-68 T 22-04-2016 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 HRM2_RS13510 fe13dd8ba79f29fbf53ab2796843d10e 416 SUPERFAMILY SSF53300 49 217 2.97E-12 T 22-04-2016 IPR002035 von Willebrand factor, type A HRM2_RS13510 fe13dd8ba79f29fbf53ab2796843d10e 416 PANTHER PTHR30128:SF10 243 412 1.2E-48 T 22-04-2016 HRM2_RS13510 fe13dd8ba79f29fbf53ab2796843d10e 416 PRINTS PR01021 OMPA domain signature 314 336 1.6E-14 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 HRM2_RS13510 fe13dd8ba79f29fbf53ab2796843d10e 416 PRINTS PR01021 OMPA domain signature 344 359 1.6E-14 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 HRM2_RS13510 fe13dd8ba79f29fbf53ab2796843d10e 416 PRINTS PR01021 OMPA domain signature 359 375 1.6E-14 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 HRM2_RS13510 fe13dd8ba79f29fbf53ab2796843d10e 416 PANTHER PTHR30128 243 412 1.2E-48 T 22-04-2016 HRM2_RS13510 fe13dd8ba79f29fbf53ab2796843d10e 416 Gene3D G3DSA:3.40.50.410 51 201 1.9E-8 T 22-04-2016 IPR002035 von Willebrand factor, type A HRM2_RS13510 fe13dd8ba79f29fbf53ab2796843d10e 416 SUPERFAMILY SSF103088 303 412 1.2E-35 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS13510 fe13dd8ba79f29fbf53ab2796843d10e 416 Pfam PF13519 von Willebrand factor type A domain 51 163 1.4E-6 T 22-04-2016 IPR002035 von Willebrand factor, type A HRM2_RS13510 fe13dd8ba79f29fbf53ab2796843d10e 416 Pfam PF02412 Thrombospondin type 3 repeat 276 296 0.021 T 22-04-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: REACT_16888 HRM2_RS13510 fe13dd8ba79f29fbf53ab2796843d10e 416 Pfam PF02412 Thrombospondin type 3 repeat 249 266 0.012 T 22-04-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: REACT_16888 HRM2_RS13510 fe13dd8ba79f29fbf53ab2796843d10e 416 Gene3D G3DSA:4.10.1080.10 227 296 1.0E-10 T 22-04-2016 IPR028974 TSP type-3 repeat GO:0005509 HRM2_RS13510 fe13dd8ba79f29fbf53ab2796843d10e 416 Pfam PF00691 OmpA family 313 408 2.1E-23 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS13510 fe13dd8ba79f29fbf53ab2796843d10e 416 SMART SM00327 46 231 8.9E-4 T 22-04-2016 IPR002035 von Willebrand factor, type A HRM2_RS13510 fe13dd8ba79f29fbf53ab2796843d10e 416 SUPERFAMILY SSF103647 245 317 1.7E-15 T 22-04-2016 IPR028974 TSP type-3 repeat GO:0005509 HRM2_RS13510 fe13dd8ba79f29fbf53ab2796843d10e 416 Gene3D G3DSA:3.30.1330.60 310 412 4.5E-39 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS13510 fe13dd8ba79f29fbf53ab2796843d10e 416 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 397 416 4.0E-5 T 22-04-2016 HRM2_RS13510 fe13dd8ba79f29fbf53ab2796843d10e 416 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 359 376 4.0E-5 T 22-04-2016 HRM2_RS13510 fe13dd8ba79f29fbf53ab2796843d10e 416 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 377 396 4.0E-5 T 22-04-2016 HRM2_RS08380 db0415c0ff7c8ed1e06b47166ddecf5b 376 Pfam PF00384 Molybdopterin oxidoreductase 301 375 1.5E-13 T 22-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 HRM2_RS08380 db0415c0ff7c8ed1e06b47166ddecf5b 376 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 8 78 2.0E-15 T 22-04-2016 HRM2_RS08380 db0415c0ff7c8ed1e06b47166ddecf5b 376 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 215 226 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS08380 db0415c0ff7c8ed1e06b47166ddecf5b 376 Gene3D G3DSA:2.20.25.90 250 300 4.5E-24 T 22-04-2016 HRM2_RS08380 db0415c0ff7c8ed1e06b47166ddecf5b 376 Gene3D G3DSA:3.30.70.20 157 218 5.3E-15 T 22-04-2016 HRM2_RS08380 db0415c0ff7c8ed1e06b47166ddecf5b 376 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 245 298 5.8E-18 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS08380 db0415c0ff7c8ed1e06b47166ddecf5b 376 Gene3D G3DSA:3.10.20.30 9 58 9.2E-8 T 22-04-2016 IPR012675 Beta-grasp domain HRM2_RS08380 db0415c0ff7c8ed1e06b47166ddecf5b 376 SMART SM00926 244 298 4.9E-22 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS08380 db0415c0ff7c8ed1e06b47166ddecf5b 376 Pfam PF12838 4Fe-4S dicluster domain 171 229 5.2E-9 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS08380 db0415c0ff7c8ed1e06b47166ddecf5b 376 SUPERFAMILY SSF54862 77 234 1.4E-32 T 22-04-2016 HRM2_RS08380 db0415c0ff7c8ed1e06b47166ddecf5b 376 SUPERFAMILY SSF54292 6 103 7.76E-25 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 HRM2_RS08380 db0415c0ff7c8ed1e06b47166ddecf5b 376 PANTHER PTHR11615 242 376 1.0E-57 T 22-04-2016 HRM2_RS08380 db0415c0ff7c8ed1e06b47166ddecf5b 376 PANTHER PTHR11615 5 53 1.0E-57 T 22-04-2016 HRM2_RS08380 db0415c0ff7c8ed1e06b47166ddecf5b 376 SUPERFAMILY SSF53706 213 375 9.95E-61 T 22-04-2016 HRM2_RS08380 db0415c0ff7c8ed1e06b47166ddecf5b 376 Gene3D G3DSA:3.40.50.740 301 373 4.4E-23 T 22-04-2016 HRM2_RS08380 db0415c0ff7c8ed1e06b47166ddecf5b 376 PANTHER PTHR11615:SF112 242 376 1.0E-57 T 22-04-2016 HRM2_RS08380 db0415c0ff7c8ed1e06b47166ddecf5b 376 PANTHER PTHR11615:SF112 5 53 1.0E-57 T 22-04-2016 HRM2_RS08380 db0415c0ff7c8ed1e06b47166ddecf5b 376 Gene3D G3DSA:3.30.70.20 219 249 2.0E-5 T 22-04-2016 HRM2_RS02320 101e68aa6eb180268643b80b569e6e06 695 Gene3D G3DSA:3.30.230.70 5 222 1.6E-78 T 22-04-2016 IPR027408 PNPase/RNase PH domain HRM2_RS02320 101e68aa6eb180268643b80b569e6e06 695 Gene3D G3DSA:3.30.230.70 313 539 5.4E-81 T 22-04-2016 IPR027408 PNPase/RNase PH domain HRM2_RS02320 101e68aa6eb180268643b80b569e6e06 695 SMART SM00316 618 688 9.6E-23 T 22-04-2016 IPR022967 RNA-binding domain, S1 HRM2_RS02320 101e68aa6eb180268643b80b569e6e06 695 Pfam PF00013 KH domain 554 609 6.4E-8 T 22-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 HRM2_RS02320 101e68aa6eb180268643b80b569e6e06 695 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 9 689 2.1E-298 T 22-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 HRM2_RS02320 101e68aa6eb180268643b80b569e6e06 695 SUPERFAMILY SSF55666 144 236 9.96E-29 T 22-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 HRM2_RS02320 101e68aa6eb180268643b80b569e6e06 695 Gene3D G3DSA:1.10.10.400 225 312 1.7E-24 T 22-04-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 HRM2_RS02320 101e68aa6eb180268643b80b569e6e06 695 Pfam PF00575 S1 RNA binding domain 617 688 8.4E-19 T 22-04-2016 IPR003029 S1 domain GO:0003676 HRM2_RS02320 101e68aa6eb180268643b80b569e6e06 695 SMART SM00322 550 615 1.8E-9 T 22-04-2016 IPR004087 K Homology domain GO:0003676 HRM2_RS02320 101e68aa6eb180268643b80b569e6e06 695 Gene3D G3DSA:3.30.1370.10 549 619 1.7E-21 T 22-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 HRM2_RS02320 101e68aa6eb180268643b80b569e6e06 695 Pfam PF01138 3' exoribonuclease family, domain 1 321 454 5.7E-21 T 22-04-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: REACT_21257 HRM2_RS02320 101e68aa6eb180268643b80b569e6e06 695 Pfam PF01138 3' exoribonuclease family, domain 1 13 143 1.0E-20 T 22-04-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: REACT_21257 HRM2_RS02320 101e68aa6eb180268643b80b569e6e06 695 PANTHER PTHR11252 4 693 0.0 T 22-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 HRM2_RS02320 101e68aa6eb180268643b80b569e6e06 695 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 240 317 2.6E-14 T 22-04-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 HRM2_RS02320 101e68aa6eb180268643b80b569e6e06 695 SUPERFAMILY SSF50249 608 692 1.2E-19 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS02320 101e68aa6eb180268643b80b569e6e06 695 Pfam PF03725 3' exoribonuclease family, domain 2 457 525 2.8E-5 T 22-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 HRM2_RS02320 101e68aa6eb180268643b80b569e6e06 695 Pfam PF03725 3' exoribonuclease family, domain 2 146 209 9.2E-16 T 22-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 HRM2_RS02320 101e68aa6eb180268643b80b569e6e06 695 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 1 691 29.737 T 22-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 HRM2_RS02320 101e68aa6eb180268643b80b569e6e06 695 Gene3D G3DSA:2.40.50.140 620 693 8.9E-24 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS02320 101e68aa6eb180268643b80b569e6e06 695 SUPERFAMILY SSF54211 6 143 3.34E-45 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS02320 101e68aa6eb180268643b80b569e6e06 695 SUPERFAMILY SSF54791 553 636 8.06E-16 T 22-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 HRM2_RS02320 101e68aa6eb180268643b80b569e6e06 695 SUPERFAMILY SSF55666 448 546 9.26E-26 T 22-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 HRM2_RS02320 101e68aa6eb180268643b80b569e6e06 695 SUPERFAMILY SSF54211 289 485 3.29E-47 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS02320 101e68aa6eb180268643b80b569e6e06 695 PIRSF PIRSF005499 1 695 9.6E-286 T 22-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 HRM2_RS09345 c490433463b3f7222381dee9ec381923 160 PIRSF PIRSF001220 1 159 1.3E-24 T 22-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 HRM2_RS09345 c490433463b3f7222381dee9ec381923 160 PIRSF PIRSF500176 1 158 1.9E-25 T 22-04-2016 HRM2_RS09345 c490433463b3f7222381dee9ec381923 160 PRINTS PR00139 Asparaginase/glutaminase family signature 3 14 1.1E-6 T 22-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 HRM2_RS09345 c490433463b3f7222381dee9ec381923 160 PRINTS PR00139 Asparaginase/glutaminase family signature 74 92 1.1E-6 T 22-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 HRM2_RS09345 c490433463b3f7222381dee9ec381923 160 SUPERFAMILY SSF53774 2 152 5.36E-35 T 22-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 HRM2_RS09345 c490433463b3f7222381dee9ec381923 160 Pfam PF00710 Asparaginase, N-terminal 2 152 2.4E-27 T 22-04-2016 IPR027474 L-asparaginase, N-terminal HRM2_RS09345 c490433463b3f7222381dee9ec381923 160 Gene3D G3DSA:3.40.50.1170 2 153 9.5E-34 T 22-04-2016 IPR027474 L-asparaginase, N-terminal HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 Pfam PF04561 RNA polymerase Rpb2, domain 2 355 461 2.9E-16 T 22-04-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 Pfam PF04561 RNA polymerase Rpb2, domain 2 170 228 6.1E-7 T 22-04-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1399 12.161 T 22-04-2016 IPR010243 DNA-directed RNA polymerase, beta subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 Gene3D G3DSA:2.30.150.10 599 663 1.5E-19 T 22-04-2016 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 Pfam PF10385 RNA polymerase beta subunit external 1 domain 598 663 5.3E-18 T 22-04-2016 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 Gene3D G3DSA:2.40.50.150 834 944 2.2E-53 T 22-04-2016 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 Gene3D G3DSA:2.40.50.150 1070 1084 2.2E-53 T 22-04-2016 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 Gene3D G3DSA:2.40.50.100 721 799 1.9E-28 T 22-04-2016 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 SUPERFAMILY SSF64484 1064 1161 0.0 T 22-04-2016 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 SUPERFAMILY SSF64484 350 946 0.0 T 22-04-2016 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 SUPERFAMILY SSF64484 11 232 0.0 T 22-04-2016 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 SUPERFAMILY SSF64484 1218 1398 0.0 T 22-04-2016 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 Gene3D G3DSA:2.40.270.10 1221 1299 5.7E-82 T 22-04-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 Gene3D G3DSA:2.40.270.10 1085 1176 5.7E-82 T 22-04-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 Gene3D G3DSA:2.40.270.10 800 827 5.7E-82 T 22-04-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 Gene3D G3DSA:3.90.1100.10 20 157 1.5E-144 T 22-04-2016 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 Gene3D G3DSA:3.90.1100.10 666 720 1.5E-144 T 22-04-2016 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 Gene3D G3DSA:3.90.1100.10 452 598 1.5E-144 T 22-04-2016 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 Pfam PF00562 RNA polymerase Rpb2, domain 6 724 1321 1.4E-160 T 22-04-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 Pfam PF04565 RNA polymerase Rpb2, domain 3 520 588 7.3E-30 T 22-04-2016 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 PANTHER PTHR20856 1059 1153 0.0 T 22-04-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 PANTHER PTHR20856 347 732 0.0 T 22-04-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 PANTHER PTHR20856 9 235 0.0 T 22-04-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 PANTHER PTHR20856 750 937 0.0 T 22-04-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 PANTHER PTHR20856 1239 1401 0.0 T 22-04-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 9 1396 0.0 T 22-04-2016 IPR010243 DNA-directed RNA polymerase, beta subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 Pfam PF04560 RNA polymerase Rpb2, domain 7 1323 1397 1.8E-24 T 22-04-2016 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 Pfam PF04563 RNA polymerase beta subunit 27 506 2.5E-27 T 22-04-2016 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 PANTHER PTHR20856:SF20 1059 1153 0.0 T 22-04-2016 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 PANTHER PTHR20856:SF20 347 732 0.0 T 22-04-2016 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 PANTHER PTHR20856:SF20 9 235 0.0 T 22-04-2016 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 PANTHER PTHR20856:SF20 750 937 0.0 T 22-04-2016 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 PANTHER PTHR20856:SF20 1239 1401 0.0 T 22-04-2016 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 Gene3D G3DSA:3.90.1110.10 353 451 4.1E-61 T 22-04-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 Gene3D G3DSA:3.90.1110.10 159 236 4.1E-61 T 22-04-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS17930 ebaadab605f8bd9c3e7303e08d4f71ac 1401 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1088 1100 - T 22-04-2016 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS08370 af3a729c8add7504c474ad192734f0d5 313 PANTHER PTHR11079 3 307 9.1E-108 T 22-04-2016 HRM2_RS08370 af3a729c8add7504c474ad192734f0d5 313 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 11 305 4.7E-83 T 22-04-2016 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS08370 af3a729c8add7504c474ad192734f0d5 313 Gene3D G3DSA:3.10.290.10 11 60 1.4E-6 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HRM2_RS08370 af3a729c8add7504c474ad192734f0d5 313 Pfam PF01479 S4 domain 14 60 4.9E-7 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HRM2_RS08370 af3a729c8add7504c474ad192734f0d5 313 SUPERFAMILY SSF55120 76 306 2.67E-70 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS08370 af3a729c8add7504c474ad192734f0d5 313 Pfam PF00849 RNA pseudouridylate synthase 90 245 7.3E-35 T 22-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS08370 af3a729c8add7504c474ad192734f0d5 313 SUPERFAMILY SSF55174 11 101 3.34E-9 T 22-04-2016 HRM2_RS08370 af3a729c8add7504c474ad192734f0d5 313 SMART SM00363 14 75 1.0E-4 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HRM2_RS08370 af3a729c8add7504c474ad192734f0d5 313 PANTHER PTHR11079:SF73 3 307 9.1E-108 T 22-04-2016 HRM2_RS14335 e2ae122ca1bd7e309782be6be0499473 486 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 1 476 1.7E-146 T 22-04-2016 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622|UniPathway: UPA00164 HRM2_RS14335 e2ae122ca1bd7e309782be6be0499473 486 PANTHER PTHR12526:SF17 1 483 7.3E-119 T 22-04-2016 HRM2_RS14335 e2ae122ca1bd7e309782be6be0499473 486 Pfam PF00534 Glycosyl transferases group 1 288 427 1.0E-11 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 HRM2_RS14335 e2ae122ca1bd7e309782be6be0499473 486 Pfam PF08323 Starch synthase catalytic domain 2 237 1.1E-64 T 22-04-2016 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622|UniPathway: UPA00164 HRM2_RS14335 e2ae122ca1bd7e309782be6be0499473 486 Hamap MF_00484 Glycogen synthase [glgA]. 1 476 38.431 T 22-04-2016 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622|UniPathway: UPA00164 HRM2_RS14335 e2ae122ca1bd7e309782be6be0499473 486 PANTHER PTHR12526 1 483 7.3E-119 T 22-04-2016 HRM2_RS14335 e2ae122ca1bd7e309782be6be0499473 486 Gene3D G3DSA:3.40.50.2000 251 456 1.5E-61 T 22-04-2016 HRM2_RS14335 e2ae122ca1bd7e309782be6be0499473 486 SUPERFAMILY SSF53756 3 479 5.93E-112 T 22-04-2016 HRM2_RS20885 f055ad401c513ca077e9e5055cd6652a 382 TIGRFAM TIGR02066 dsrB: sulfite reductase, dissimilatory-type beta subunit 33 382 1.8E-146 T 22-04-2016 IPR011808 Sulphite reductase, dissimilatory-type beta subunit GO:0006790|GO:0009055|GO:0018551|GO:0051539 KEGG: 00920+1.8.99.5|MetaCyc: PWY-5306|MetaCyc: PWY-5360 HRM2_RS20885 f055ad401c513ca077e9e5055cd6652a 382 PANTHER PTHR11493 274 370 2.6E-85 T 22-04-2016 HRM2_RS20885 f055ad401c513ca077e9e5055cd6652a 382 PANTHER PTHR11493 19 206 2.6E-85 T 22-04-2016 HRM2_RS20885 f055ad401c513ca077e9e5055cd6652a 382 Pfam PF12838 4Fe-4S dicluster domain 228 271 2.8E-6 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS20885 f055ad401c513ca077e9e5055cd6652a 382 PANTHER PTHR11493:SF51 274 370 2.6E-85 T 22-04-2016 HRM2_RS20885 f055ad401c513ca077e9e5055cd6652a 382 PANTHER PTHR11493:SF51 19 206 2.6E-85 T 22-04-2016 HRM2_RS20885 f055ad401c513ca077e9e5055cd6652a 382 Gene3D G3DSA:3.30.70.20 202 271 2.8E-8 T 22-04-2016 HRM2_RS20885 f055ad401c513ca077e9e5055cd6652a 382 Gene3D G3DSA:3.30.413.10 281 354 1.3E-17 T 22-04-2016 HRM2_RS20885 f055ad401c513ca077e9e5055cd6652a 382 Gene3D G3DSA:3.30.413.10 139 201 1.3E-17 T 22-04-2016 HRM2_RS20885 f055ad401c513ca077e9e5055cd6652a 382 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 259 270 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS20885 f055ad401c513ca077e9e5055cd6652a 382 SUPERFAMILY SSF54862 187 271 6.4E-10 T 22-04-2016 HRM2_RS20885 f055ad401c513ca077e9e5055cd6652a 382 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 136 361 6.8E-37 T 22-04-2016 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 HRM2_RS20885 f055ad401c513ca077e9e5055cd6652a 382 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 55 119 8.1E-12 T 22-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 HRM2_RS20885 f055ad401c513ca077e9e5055cd6652a 382 SUPERFAMILY SSF55124 2 142 2.62E-58 T 22-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 HRM2_RS20885 f055ad401c513ca077e9e5055cd6652a 382 SUPERFAMILY SSF56014 136 209 2.91E-40 T 22-04-2016 HRM2_RS20885 f055ad401c513ca077e9e5055cd6652a 382 SUPERFAMILY SSF56014 279 378 2.91E-40 T 22-04-2016 HRM2_RS16600 eca149f35360904afb446abf27e1f575 175 Gene3D G3DSA:3.30.70.20 122 164 2.0E-8 T 22-04-2016 HRM2_RS16600 eca149f35360904afb446abf27e1f575 175 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 100 111 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS16600 eca149f35360904afb446abf27e1f575 175 Gene3D G3DSA:3.30.70.20 18 79 9.7E-11 T 22-04-2016 HRM2_RS16600 eca149f35360904afb446abf27e1f575 175 Pfam PF13247 4Fe-4S dicluster domain 63 153 1.6E-19 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS16600 eca149f35360904afb446abf27e1f575 175 SUPERFAMILY SSF54862 12 154 2.34E-47 T 22-04-2016 HRM2_RS16600 eca149f35360904afb446abf27e1f575 175 PANTHER PTHR11938:SF88 19 151 1.8E-29 T 22-04-2016 HRM2_RS16600 eca149f35360904afb446abf27e1f575 175 Pfam PF12800 4Fe-4S binding domain 19 34 0.018 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS16600 eca149f35360904afb446abf27e1f575 175 Gene3D G3DSA:3.30.70.20 80 121 9.0E-21 T 22-04-2016 HRM2_RS16600 eca149f35360904afb446abf27e1f575 175 PRINTS PR00354 7Fe ferredoxin signature 77 87 2.2E-5 T 22-04-2016 IPR000813 7Fe ferredoxin GO:0009055 HRM2_RS16600 eca149f35360904afb446abf27e1f575 175 PRINTS PR00354 7Fe ferredoxin signature 95 112 2.2E-5 T 22-04-2016 IPR000813 7Fe ferredoxin GO:0009055 HRM2_RS16600 eca149f35360904afb446abf27e1f575 175 PRINTS PR00354 7Fe ferredoxin signature 67 77 2.2E-5 T 22-04-2016 IPR000813 7Fe ferredoxin GO:0009055 HRM2_RS16600 eca149f35360904afb446abf27e1f575 175 PANTHER PTHR11938 19 151 1.8E-29 T 22-04-2016 HRM2_RS16490 6b33c702df2058447defd6c55e0e9863 124 Pfam PF00072 Response regulator receiver domain 6 117 3.8E-25 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS16490 6b33c702df2058447defd6c55e0e9863 124 SUPERFAMILY SSF52172 1 122 2.7E-35 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS16490 6b33c702df2058447defd6c55e0e9863 124 SMART SM00448 4 117 5.6E-33 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS16490 6b33c702df2058447defd6c55e0e9863 124 Gene3D G3DSA:3.40.50.2300 3 122 1.1E-38 T 22-04-2016 HRM2_RS16490 6b33c702df2058447defd6c55e0e9863 124 PANTHER PTHR24423 6 121 5.7E-37 T 22-04-2016 HRM2_RS18595 2bc4ee39f4e787ccba7221ac4bb0e07c 283 Gene3D G3DSA:3.10.310.10 1 126 1.6E-51 T 22-04-2016 HRM2_RS18595 2bc4ee39f4e787ccba7221ac4bb0e07c 283 SUPERFAMILY SSF54506 148 282 5.76E-50 T 22-04-2016 HRM2_RS18595 2bc4ee39f4e787ccba7221ac4bb0e07c 283 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 283 38.074 T 22-04-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 HRM2_RS18595 2bc4ee39f4e787ccba7221ac4bb0e07c 283 PANTHER PTHR31689 1 283 4.8E-127 T 22-04-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 HRM2_RS18595 2bc4ee39f4e787ccba7221ac4bb0e07c 283 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 67 81 - T 22-04-2016 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 HRM2_RS18595 2bc4ee39f4e787ccba7221ac4bb0e07c 283 Gene3D G3DSA:3.10.310.10 127 270 4.7E-53 T 22-04-2016 HRM2_RS18595 2bc4ee39f4e787ccba7221ac4bb0e07c 283 PANTHER PTHR31689:SF0 1 283 4.8E-127 T 22-04-2016 HRM2_RS18595 2bc4ee39f4e787ccba7221ac4bb0e07c 283 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 4 281 1.1E-91 T 22-04-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 HRM2_RS18595 2bc4ee39f4e787ccba7221ac4bb0e07c 283 SUPERFAMILY SSF54506 3 138 6.28E-40 T 22-04-2016 HRM2_RS18595 2bc4ee39f4e787ccba7221ac4bb0e07c 283 Pfam PF01678 Diaminopimelate epimerase 5 129 2.1E-32 T 22-04-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 HRM2_RS18595 2bc4ee39f4e787ccba7221ac4bb0e07c 283 Pfam PF01678 Diaminopimelate epimerase 161 276 1.4E-31 T 22-04-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 HRM2_RS15195 0de5cf3df56e119efa2459e34bf3e510 307 SUPERFAMILY SSF51730 5 303 1.41E-75 T 22-04-2016 IPR029041 FAD-linked oxidoreductase-like HRM2_RS15195 0de5cf3df56e119efa2459e34bf3e510 307 Gene3D G3DSA:3.20.20.220 2 304 1.8E-65 T 22-04-2016 IPR029041 FAD-linked oxidoreductase-like HRM2_RS15195 0de5cf3df56e119efa2459e34bf3e510 307 Pfam PF02219 Methylenetetrahydrofolate reductase 6 300 1.2E-41 T 22-04-2016 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 HRM2_RS03075 447a91bad6a93f2ec42ec17a83d76a49 504 PANTHER PTHR24220:SF239 8 383 9.6E-172 T 22-04-2016 HRM2_RS03075 447a91bad6a93f2ec42ec17a83d76a49 504 SUPERFAMILY SSF52540 7 225 1.11E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03075 447a91bad6a93f2ec42ec17a83d76a49 504 SUPERFAMILY SSF52540 237 482 5.6E-37 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03075 447a91bad6a93f2ec42ec17a83d76a49 504 Gene3D G3DSA:3.40.50.300 255 482 3.1E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03075 447a91bad6a93f2ec42ec17a83d76a49 504 Gene3D G3DSA:3.40.50.300 6 231 6.6E-63 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03075 447a91bad6a93f2ec42ec17a83d76a49 504 SMART SM00382 31 221 5.9E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS03075 447a91bad6a93f2ec42ec17a83d76a49 504 PANTHER PTHR24220 8 383 9.6E-172 T 22-04-2016 HRM2_RS03075 447a91bad6a93f2ec42ec17a83d76a49 504 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS03075 447a91bad6a93f2ec42ec17a83d76a49 504 ProSitePatterns PS00211 ABC transporters family signature. 403 417 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS03075 447a91bad6a93f2ec42ec17a83d76a49 504 Pfam PF00005 ABC transporter 24 170 8.1E-32 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS03075 447a91bad6a93f2ec42ec17a83d76a49 504 Pfam PF00005 ABC transporter 274 430 6.4E-12 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS20675 94460793137c62c750f92460a0943937 142 SUPERFAMILY SSF52788 12 133 1.16E-26 T 22-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily HRM2_RS20675 94460793137c62c750f92460a0943937 142 PANTHER PTHR11717 13 135 5.0E-19 T 22-04-2016 HRM2_RS20675 94460793137c62c750f92460a0943937 142 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 12 132 1.5E-13 T 22-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily HRM2_RS20675 94460793137c62c750f92460a0943937 142 SMART SM00226 13 135 4.6E-21 T 22-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily HRM2_RS20675 94460793137c62c750f92460a0943937 142 Gene3D G3DSA:3.40.50.270 12 134 1.8E-27 T 22-04-2016 HRM2_RS20675 94460793137c62c750f92460a0943937 142 PANTHER PTHR11717:SF18 13 135 5.0E-19 T 22-04-2016 HRM2_RS19640 6385402586c23aceac94ce17d252f826 509 SUPERFAMILY SSF51395 444 488 1.04E-19 T 22-04-2016 HRM2_RS19640 6385402586c23aceac94ce17d252f826 509 SUPERFAMILY SSF51395 97 413 1.04E-19 T 22-04-2016 HRM2_RS19640 6385402586c23aceac94ce17d252f826 509 Gene3D G3DSA:3.20.20.70 53 499 2.4E-18 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS19640 6385402586c23aceac94ce17d252f826 509 Pfam PF01645 Conserved region in glutamate synthase 276 391 2.5E-7 T 22-04-2016 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 HRM2_RS17805 293c0b1c331a3015ee93ae99d8378b10 437 Hamap MF_01465 Protein translocase subunit SecY [secY]. 6 427 31.302 T 22-04-2016 IPR026593 Protein translocase subunit SecY HRM2_RS17805 293c0b1c331a3015ee93ae99d8378b10 437 Pfam PF00344 SecY translocase 72 411 8.9E-123 T 22-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 HRM2_RS17805 293c0b1c331a3015ee93ae99d8378b10 437 PANTHER PTHR10906:SF2 2 431 1.3E-211 T 22-04-2016 HRM2_RS17805 293c0b1c331a3015ee93ae99d8378b10 437 ProSitePatterns PS00756 Protein secY signature 2. 171 188 - T 22-04-2016 IPR030659 SecY conserved site HRM2_RS17805 293c0b1c331a3015ee93ae99d8378b10 437 PIRSF PIRSF004557 6 433 9.2E-128 T 22-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 HRM2_RS17805 293c0b1c331a3015ee93ae99d8378b10 437 Gene3D G3DSA:1.10.3370.10 7 430 3.8E-168 T 22-04-2016 IPR023201 SecY subunit domain HRM2_RS17805 293c0b1c331a3015ee93ae99d8378b10 437 SUPERFAMILY SSF103491 6 418 3.27E-132 T 22-04-2016 IPR023201 SecY subunit domain HRM2_RS17805 293c0b1c331a3015ee93ae99d8378b10 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 396 414 2.7E-94 T 22-04-2016 HRM2_RS17805 293c0b1c331a3015ee93ae99d8378b10 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 270 289 2.7E-94 T 22-04-2016 HRM2_RS17805 293c0b1c331a3015ee93ae99d8378b10 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 178 201 2.7E-94 T 22-04-2016 HRM2_RS17805 293c0b1c331a3015ee93ae99d8378b10 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 364 382 2.7E-94 T 22-04-2016 HRM2_RS17805 293c0b1c331a3015ee93ae99d8378b10 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 309 331 2.7E-94 T 22-04-2016 HRM2_RS17805 293c0b1c331a3015ee93ae99d8378b10 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 112 135 2.7E-94 T 22-04-2016 HRM2_RS17805 293c0b1c331a3015ee93ae99d8378b10 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 71 91 2.7E-94 T 22-04-2016 HRM2_RS17805 293c0b1c331a3015ee93ae99d8378b10 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 19 37 2.7E-94 T 22-04-2016 HRM2_RS17805 293c0b1c331a3015ee93ae99d8378b10 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 152 177 2.7E-94 T 22-04-2016 HRM2_RS17805 293c0b1c331a3015ee93ae99d8378b10 437 ProSitePatterns PS00755 Protein secY signature 1. 72 91 - T 22-04-2016 IPR030659 SecY conserved site HRM2_RS17805 293c0b1c331a3015ee93ae99d8378b10 437 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 16 423 7.7E-127 T 22-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 HRM2_RS17805 293c0b1c331a3015ee93ae99d8378b10 437 PANTHER PTHR10906 2 431 1.3E-211 T 22-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 HRM2_RS25395 4872e0e80f5d5a74e59d1eb3931de65c 576 Gene3D G3DSA:3.40.50.2300 13 134 2.0E-35 T 22-04-2016 HRM2_RS25395 4872e0e80f5d5a74e59d1eb3931de65c 576 Pfam PF00990 Diguanylate cyclase, GGDEF domain 406 566 6.5E-53 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS25395 4872e0e80f5d5a74e59d1eb3931de65c 576 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 267 384 6.6E-21 T 22-04-2016 IPR000014 PAS domain HRM2_RS25395 4872e0e80f5d5a74e59d1eb3931de65c 576 SUPERFAMILY SSF55073 409 568 1.07E-48 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS25395 4872e0e80f5d5a74e59d1eb3931de65c 576 Gene3D G3DSA:3.30.70.270 407 568 6.3E-52 T 22-04-2016 HRM2_RS25395 4872e0e80f5d5a74e59d1eb3931de65c 576 SMART SM00086 337 379 1.5E-7 T 22-04-2016 IPR001610 PAC motif HRM2_RS25395 4872e0e80f5d5a74e59d1eb3931de65c 576 SMART SM00086 215 257 0.032 T 22-04-2016 IPR001610 PAC motif HRM2_RS25395 4872e0e80f5d5a74e59d1eb3931de65c 576 Gene3D G3DSA:3.30.450.20 135 272 4.9E-16 T 22-04-2016 HRM2_RS25395 4872e0e80f5d5a74e59d1eb3931de65c 576 SUPERFAMILY SSF55785 149 260 1.06E-9 T 22-04-2016 IPR000014 PAS domain HRM2_RS25395 4872e0e80f5d5a74e59d1eb3931de65c 576 Pfam PF13426 PAS domain 278 377 3.2E-15 T 22-04-2016 IPR000014 PAS domain HRM2_RS25395 4872e0e80f5d5a74e59d1eb3931de65c 576 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 400 569 5.5E-56 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS25395 4872e0e80f5d5a74e59d1eb3931de65c 576 SMART SM00091 141 209 25.0 T 22-04-2016 IPR000014 PAS domain HRM2_RS25395 4872e0e80f5d5a74e59d1eb3931de65c 576 SMART SM00091 265 331 8.5E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS25395 4872e0e80f5d5a74e59d1eb3931de65c 576 SMART SM00267 393 570 2.3E-65 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS25395 4872e0e80f5d5a74e59d1eb3931de65c 576 PANTHER PTHR26402 13 163 4.1E-37 T 22-04-2016 HRM2_RS25395 4872e0e80f5d5a74e59d1eb3931de65c 576 SUPERFAMILY SSF55785 274 376 6.63E-29 T 22-04-2016 IPR000014 PAS domain HRM2_RS25395 4872e0e80f5d5a74e59d1eb3931de65c 576 SUPERFAMILY SSF52172 13 148 1.02E-36 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS25395 4872e0e80f5d5a74e59d1eb3931de65c 576 SMART SM00448 10 123 1.3E-33 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS25395 4872e0e80f5d5a74e59d1eb3931de65c 576 Pfam PF00072 Response regulator receiver domain 13 123 8.6E-27 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS25395 4872e0e80f5d5a74e59d1eb3931de65c 576 Gene3D G3DSA:3.30.450.20 276 377 3.1E-25 T 22-04-2016 HRM2_RS00600 2dbc3973c937bd0554fd08314b68fce3 520 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 57 497 3.7E-134 T 22-04-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 HRM2_RS00600 2dbc3973c937bd0554fd08314b68fce3 520 PANTHER PTHR30047 3 498 1.8E-134 T 22-04-2016 HRM2_RS00600 2dbc3973c937bd0554fd08314b68fce3 520 ProSitePatterns PS01303 BCCT family of transporters signature. 312 321 - T 22-04-2016 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 HRM2_RS00600 2dbc3973c937bd0554fd08314b68fce3 520 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 10 497 1.4E-146 T 22-04-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 HRM2_RS00230 2dbc3973c937bd0554fd08314b68fce3 520 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 57 497 3.7E-134 T 22-04-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 HRM2_RS00230 2dbc3973c937bd0554fd08314b68fce3 520 PANTHER PTHR30047 3 498 1.8E-134 T 22-04-2016 HRM2_RS00230 2dbc3973c937bd0554fd08314b68fce3 520 ProSitePatterns PS01303 BCCT family of transporters signature. 312 321 - T 22-04-2016 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 HRM2_RS00230 2dbc3973c937bd0554fd08314b68fce3 520 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 10 497 1.4E-146 T 22-04-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 HRM2_RS15425 dc90593eac80e0848930ec461ee30d34 157 PANTHER PTHR21058 3 157 1.1E-72 T 22-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 HRM2_RS15425 dc90593eac80e0848930ec461ee30d34 157 Gene3D G3DSA:3.40.50.960 2 155 2.3E-65 T 22-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 HRM2_RS15425 dc90593eac80e0848930ec461ee30d34 157 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 15 151 9.8E-55 T 22-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 HRM2_RS15425 dc90593eac80e0848930ec461ee30d34 157 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 14 151 9.2E-57 T 22-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 HRM2_RS15425 dc90593eac80e0848930ec461ee30d34 157 SUPERFAMILY SSF52121 6 152 1.28E-59 T 22-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 HRM2_RS15425 dc90593eac80e0848930ec461ee30d34 157 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 9 154 30.702 T 22-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 HRM2_RS20010 2da36bb02de25bd476720fd0e28d6f9c 451 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 252 361 1.2E-27 T 22-04-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS20010 2da36bb02de25bd476720fd0e28d6f9c 451 Gene3D G3DSA:3.40.120.10 244 360 3.9E-46 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS20010 2da36bb02de25bd476720fd0e28d6f9c 451 SUPERFAMILY SSF53738 4 126 3.39E-40 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS20010 2da36bb02de25bd476720fd0e28d6f9c 451 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 150 247 3.7E-23 T 22-04-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS20010 2da36bb02de25bd476720fd0e28d6f9c 451 Gene3D G3DSA:3.30.310.50 364 448 4.7E-26 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS20010 2da36bb02de25bd476720fd0e28d6f9c 451 Gene3D G3DSA:3.40.120.10 166 243 6.4E-26 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS20010 2da36bb02de25bd476720fd0e28d6f9c 451 SUPERFAMILY SSF53738 149 249 9.03E-27 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS20010 2da36bb02de25bd476720fd0e28d6f9c 451 SUPERFAMILY SSF53738 252 359 1.73E-34 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS20010 2da36bb02de25bd476720fd0e28d6f9c 451 PANTHER PTHR22573:SF28 5 451 8.0E-167 T 22-04-2016 HRM2_RS20010 2da36bb02de25bd476720fd0e28d6f9c 451 Gene3D G3DSA:3.40.120.10 5 114 1.1E-37 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS20010 2da36bb02de25bd476720fd0e28d6f9c 451 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 367 443 4.5E-12 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS20010 2da36bb02de25bd476720fd0e28d6f9c 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 198 211 8.5E-19 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS20010 2da36bb02de25bd476720fd0e28d6f9c 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 93 107 8.5E-19 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS20010 2da36bb02de25bd476720fd0e28d6f9c 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 227 242 8.5E-19 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS20010 2da36bb02de25bd476720fd0e28d6f9c 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 164 183 8.5E-19 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS20010 2da36bb02de25bd476720fd0e28d6f9c 451 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 5 114 4.8E-36 T 22-04-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS20010 2da36bb02de25bd476720fd0e28d6f9c 451 SUPERFAMILY SSF55957 363 448 6.28E-21 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS20010 2da36bb02de25bd476720fd0e28d6f9c 451 PANTHER PTHR22573 5 451 8.0E-167 T 22-04-2016 HRM2_RS12275 2234cbf722a7a0e6fbe74ff738788f0e 286 TIGRFAM TIGR02130 dapB_plant: dihydrodipicolinate reductase 6 284 4.1E-93 T 22-04-2016 IPR011859 Dihydrodipicolinate reductase, plant-type GO:0008839|GO:0009089|GO:0055114|GO:0070402 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 HRM2_RS12275 2234cbf722a7a0e6fbe74ff738788f0e 286 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 136 280 1.3E-14 T 22-04-2016 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 HRM2_RS12275 2234cbf722a7a0e6fbe74ff738788f0e 286 PANTHER PTHR20836:SF0 1 280 2.5E-73 T 22-04-2016 HRM2_RS12275 2234cbf722a7a0e6fbe74ff738788f0e 286 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 6 129 8.1E-14 T 22-04-2016 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 HRM2_RS12275 2234cbf722a7a0e6fbe74ff738788f0e 286 SUPERFAMILY SSF51735 6 130 5.25E-12 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS12275 2234cbf722a7a0e6fbe74ff738788f0e 286 SUPERFAMILY SSF51735 240 280 5.25E-12 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS12275 2234cbf722a7a0e6fbe74ff738788f0e 286 Gene3D G3DSA:3.40.50.720 6 169 3.7E-25 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS12275 2234cbf722a7a0e6fbe74ff738788f0e 286 PANTHER PTHR20836 1 280 2.5E-73 T 22-04-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 HRM2_RS15675 f6d33772c8f08a7dc58f608432bb1677 220 Pfam PF01467 Cytidylyltransferase-like 5 194 2.5E-26 T 22-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HRM2_RS15675 f6d33772c8f08a7dc58f608432bb1677 220 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 5 219 9.6E-43 T 22-04-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: REACT_11193|UniPathway: UPA00253 HRM2_RS15675 f6d33772c8f08a7dc58f608432bb1677 220 PANTHER PTHR12039 161 220 2.0E-29 T 22-04-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: REACT_11193|UniPathway: UPA00253 HRM2_RS15675 f6d33772c8f08a7dc58f608432bb1677 220 PANTHER PTHR12039 4 136 2.0E-29 T 22-04-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: REACT_11193|UniPathway: UPA00253 HRM2_RS15675 f6d33772c8f08a7dc58f608432bb1677 220 SUPERFAMILY SSF52374 2 219 1.15E-44 T 22-04-2016 HRM2_RS15675 f6d33772c8f08a7dc58f608432bb1677 220 Gene3D G3DSA:3.40.50.620 4 219 9.6E-54 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS15675 f6d33772c8f08a7dc58f608432bb1677 220 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 62 4.0E-12 T 22-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HRM2_RS15675 f6d33772c8f08a7dc58f608432bb1677 220 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 1 220 27.375 T 22-04-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: REACT_11193|UniPathway: UPA00253 HRM2_RS16475 42b78aab0a41d139d1731e0afc35c596 581 SUPERFAMILY SSF90123 10 317 5.1E-69 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HRM2_RS16475 42b78aab0a41d139d1731e0afc35c596 581 Gene3D G3DSA:3.40.50.300 336 575 7.0E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16475 42b78aab0a41d139d1731e0afc35c596 581 ProSitePatterns PS00211 ABC transporters family signature. 478 492 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS16475 42b78aab0a41d139d1731e0afc35c596 581 PANTHER PTHR24221 6 571 2.7E-173 T 22-04-2016 HRM2_RS16475 42b78aab0a41d139d1731e0afc35c596 581 Gene3D G3DSA:1.20.1560.10 10 317 5.3E-70 T 22-04-2016 HRM2_RS16475 42b78aab0a41d139d1731e0afc35c596 581 SUPERFAMILY SSF52540 327 574 7.42E-77 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16475 42b78aab0a41d139d1731e0afc35c596 581 Pfam PF00664 ABC transporter transmembrane region 22 292 1.2E-43 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HRM2_RS16475 42b78aab0a41d139d1731e0afc35c596 581 SMART SM00382 366 552 3.0E-16 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS16475 42b78aab0a41d139d1731e0afc35c596 581 Pfam PF00005 ABC transporter 357 505 4.3E-30 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS15260 d7ab170d3d92a74f27042ee3c35604ce 740 SMART SM00387 602 723 2.1E-32 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS15260 d7ab170d3d92a74f27042ee3c35604ce 740 Gene3D G3DSA:3.30.450.40 317 482 3.8E-5 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS15260 d7ab170d3d92a74f27042ee3c35604ce 740 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 603 721 4.6E-20 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS15260 d7ab170d3d92a74f27042ee3c35604ce 740 Gene3D G3DSA:1.10.287.130 489 555 1.9E-5 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS15260 d7ab170d3d92a74f27042ee3c35604ce 740 PRINTS PR00344 Bacterial sensor protein C-terminal signature 671 681 1.2E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS15260 d7ab170d3d92a74f27042ee3c35604ce 740 PRINTS PR00344 Bacterial sensor protein C-terminal signature 707 720 1.2E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS15260 d7ab170d3d92a74f27042ee3c35604ce 740 PRINTS PR00344 Bacterial sensor protein C-terminal signature 653 667 1.2E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS15260 d7ab170d3d92a74f27042ee3c35604ce 740 PRINTS PR00344 Bacterial sensor protein C-terminal signature 683 701 1.2E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS15260 d7ab170d3d92a74f27042ee3c35604ce 740 PANTHER PTHR24423:SF445 8 46 7.2E-49 T 22-04-2016 HRM2_RS15260 d7ab170d3d92a74f27042ee3c35604ce 740 PANTHER PTHR24423:SF445 293 332 7.2E-49 T 22-04-2016 HRM2_RS15260 d7ab170d3d92a74f27042ee3c35604ce 740 PANTHER PTHR24423:SF445 468 725 7.2E-49 T 22-04-2016 HRM2_RS15260 d7ab170d3d92a74f27042ee3c35604ce 740 Pfam PF00512 His Kinase A (phospho-acceptor) domain 496 557 6.5E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS15260 d7ab170d3d92a74f27042ee3c35604ce 740 SMART SM00388 493 559 9.7E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS15260 d7ab170d3d92a74f27042ee3c35604ce 740 SUPERFAMILY SSF47384 488 557 1.8E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS15260 d7ab170d3d92a74f27042ee3c35604ce 740 PANTHER PTHR24423 8 46 7.2E-49 T 22-04-2016 HRM2_RS15260 d7ab170d3d92a74f27042ee3c35604ce 740 PANTHER PTHR24423 293 332 7.2E-49 T 22-04-2016 HRM2_RS15260 d7ab170d3d92a74f27042ee3c35604ce 740 PANTHER PTHR24423 468 725 7.2E-49 T 22-04-2016 HRM2_RS15260 d7ab170d3d92a74f27042ee3c35604ce 740 SUPERFAMILY SSF109604 23 279 2.83E-54 T 22-04-2016 HRM2_RS15260 d7ab170d3d92a74f27042ee3c35604ce 740 Gene3D G3DSA:3.30.565.10 560 722 9.1E-39 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS15260 d7ab170d3d92a74f27042ee3c35604ce 740 SUPERFAMILY SSF55781 312 485 1.15E-6 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS15260 d7ab170d3d92a74f27042ee3c35604ce 740 Pfam PF08668 HDOD domain 29 222 1.9E-50 T 22-04-2016 IPR013976 Metal-dependent hydrolase HDOD HRM2_RS15260 d7ab170d3d92a74f27042ee3c35604ce 740 Gene3D G3DSA:1.10.3150.10 21 280 3.2E-64 T 22-04-2016 IPR013976 Metal-dependent hydrolase HDOD HRM2_RS15260 d7ab170d3d92a74f27042ee3c35604ce 740 SUPERFAMILY SSF55874 549 721 1.31E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS01915 e729fa8619d5b5c29caf035ac543ce8a 139 Pfam PF00717 Peptidase S24-like 55 122 3.6E-12 T 22-04-2016 IPR019759 Peptidase S24/S26A/S26B HRM2_RS01915 e729fa8619d5b5c29caf035ac543ce8a 139 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 52 62 7.2E-11 T 22-04-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 HRM2_RS01915 e729fa8619d5b5c29caf035ac543ce8a 139 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 63 74 7.2E-11 T 22-04-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 HRM2_RS01915 e729fa8619d5b5c29caf035ac543ce8a 139 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 91 103 7.2E-11 T 22-04-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 HRM2_RS01915 e729fa8619d5b5c29caf035ac543ce8a 139 PANTHER PTHR33516:SF1 19 139 6.1E-49 T 22-04-2016 HRM2_RS01915 e729fa8619d5b5c29caf035ac543ce8a 139 Gene3D G3DSA:2.10.109.10 25 139 1.7E-48 T 22-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain HRM2_RS01915 e729fa8619d5b5c29caf035ac543ce8a 139 SUPERFAMILY SSF51306 19 137 6.28E-36 T 22-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C HRM2_RS01915 e729fa8619d5b5c29caf035ac543ce8a 139 PANTHER PTHR33516 19 139 6.1E-49 T 22-04-2016 HRM2_RS19135 b648aaec1e57ae12cb507f5940826c1f 599 SUPERFAMILY SSF55785 131 236 1.06E-11 T 22-04-2016 IPR000014 PAS domain HRM2_RS19135 b648aaec1e57ae12cb507f5940826c1f 599 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 500 509 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS19135 b648aaec1e57ae12cb507f5940826c1f 599 Pfam PF02954 Bacterial regulatory protein, Fis family 556 595 1.8E-8 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS19135 b648aaec1e57ae12cb507f5940826c1f 599 SMART SM00382 305 449 4.9E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS19135 b648aaec1e57ae12cb507f5940826c1f 599 Gene3D G3DSA:1.10.8.60 459 534 5.5E-18 T 22-04-2016 HRM2_RS19135 b648aaec1e57ae12cb507f5940826c1f 599 Pfam PF00158 Sigma-54 interaction domain 286 452 5.1E-64 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS19135 b648aaec1e57ae12cb507f5940826c1f 599 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 578 598 2.0E-5 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS19135 b648aaec1e57ae12cb507f5940826c1f 599 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 561 578 2.0E-5 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS19135 b648aaec1e57ae12cb507f5940826c1f 599 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 372 387 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS19135 b648aaec1e57ae12cb507f5940826c1f 599 Gene3D G3DSA:1.10.10.60 551 598 1.8E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS19135 b648aaec1e57ae12cb507f5940826c1f 599 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 309 322 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS19135 b648aaec1e57ae12cb507f5940826c1f 599 Gene3D G3DSA:3.40.50.300 282 458 4.0E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19135 b648aaec1e57ae12cb507f5940826c1f 599 SMART SM00091 142 210 4.0E-4 T 22-04-2016 IPR000014 PAS domain HRM2_RS19135 b648aaec1e57ae12cb507f5940826c1f 599 SMART SM00091 27 94 40.0 T 22-04-2016 IPR000014 PAS domain HRM2_RS19135 b648aaec1e57ae12cb507f5940826c1f 599 Gene3D G3DSA:3.40.50.300 249 269 3.7E-4 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19135 b648aaec1e57ae12cb507f5940826c1f 599 Gene3D G3DSA:3.30.450.20 143 248 7.9E-13 T 22-04-2016 HRM2_RS19135 b648aaec1e57ae12cb507f5940826c1f 599 SUPERFAMILY SSF46689 549 597 4.35E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS19135 b648aaec1e57ae12cb507f5940826c1f 599 PANTHER PTHR32071 250 597 1.2E-130 T 22-04-2016 HRM2_RS19135 b648aaec1e57ae12cb507f5940826c1f 599 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 145 258 7.0E-9 T 22-04-2016 IPR000014 PAS domain HRM2_RS19135 b648aaec1e57ae12cb507f5940826c1f 599 SUPERFAMILY SSF52540 285 529 7.05E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19135 b648aaec1e57ae12cb507f5940826c1f 599 Pfam PF13426 PAS domain 153 250 4.1E-7 T 22-04-2016 IPR000014 PAS domain HRM2_RS19135 b648aaec1e57ae12cb507f5940826c1f 599 Gene3D G3DSA:3.30.450.20 32 123 1.2E-4 T 22-04-2016 HRM2_RS08330 29e84b07ab8772c7f342fc432e1fdfe1 708 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 155 296 4.7E-49 T 22-04-2016 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain HRM2_RS08330 29e84b07ab8772c7f342fc432e1fdfe1 708 SUPERFAMILY SSF52210 133 297 9.16E-43 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS08330 29e84b07ab8772c7f342fc432e1fdfe1 708 Gene3D G3DSA:3.40.50.720 2 131 1.2E-41 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS08330 29e84b07ab8772c7f342fc432e1fdfe1 708 Pfam PF13380 CoA binding domain 12 137 1.6E-26 T 22-04-2016 IPR003781 CoA-binding GO:0048037 HRM2_RS08330 29e84b07ab8772c7f342fc432e1fdfe1 708 Pfam PF13549 ATP-grasp domain 483 701 5.9E-70 T 22-04-2016 HRM2_RS08330 29e84b07ab8772c7f342fc432e1fdfe1 708 SUPERFAMILY SSF51735 2 138 9.85E-39 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS08330 29e84b07ab8772c7f342fc432e1fdfe1 708 SUPERFAMILY SSF56059 491 699 7.66E-35 T 22-04-2016 HRM2_RS08330 29e84b07ab8772c7f342fc432e1fdfe1 708 Gene3D G3DSA:3.40.50.261 132 292 7.3E-33 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS08330 29e84b07ab8772c7f342fc432e1fdfe1 708 SUPERFAMILY SSF52210 302 458 4.84E-40 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS08330 29e84b07ab8772c7f342fc432e1fdfe1 708 PANTHER PTHR11117 28 708 9.6E-260 T 22-04-2016 HRM2_RS08330 29e84b07ab8772c7f342fc432e1fdfe1 708 SMART SM00881 7 102 3.3E-30 T 22-04-2016 IPR003781 CoA-binding GO:0048037 HRM2_RS08330 29e84b07ab8772c7f342fc432e1fdfe1 708 Gene3D G3DSA:3.40.50.261 293 448 2.3E-20 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS08330 29e84b07ab8772c7f342fc432e1fdfe1 708 Gene3D G3DSA:3.30.470.20 497 606 1.4E-6 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS08330 29e84b07ab8772c7f342fc432e1fdfe1 708 PANTHER PTHR11117:SF8 28 708 9.6E-260 T 22-04-2016 HRM2_RS01400 d5d00732eeb17651f954921f0c1a1852 230 PANTHER PTHR36111:SF2 1 228 1.0E-88 T 22-04-2016 HRM2_RS01400 d5d00732eeb17651f954921f0c1a1852 230 Pfam PF04474 Protein of unknown function (DUF554) 2 221 5.7E-79 T 22-04-2016 IPR007563 Protein of unknown function DUF554 HRM2_RS01400 d5d00732eeb17651f954921f0c1a1852 230 PANTHER PTHR36111 1 228 1.0E-88 T 22-04-2016 HRM2_RS12855 37a6952dc4c5c29f2e6be864866e798a 524 PRINTS PR00344 Bacterial sensor protein C-terminal signature 483 501 9.0E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS12855 37a6952dc4c5c29f2e6be864866e798a 524 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 467 9.0E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS12855 37a6952dc4c5c29f2e6be864866e798a 524 PRINTS PR00344 Bacterial sensor protein C-terminal signature 507 520 9.0E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS12855 37a6952dc4c5c29f2e6be864866e798a 524 Pfam PF00072 Response regulator receiver domain 10 119 1.7E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS12855 37a6952dc4c5c29f2e6be864866e798a 524 Gene3D G3DSA:3.30.565.10 376 521 3.8E-35 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS12855 37a6952dc4c5c29f2e6be864866e798a 524 SUPERFAMILY SSF55785 153 247 4.19E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS12855 37a6952dc4c5c29f2e6be864866e798a 524 Gene3D G3DSA:3.40.50.2300 8 125 9.8E-37 T 22-04-2016 HRM2_RS12855 37a6952dc4c5c29f2e6be864866e798a 524 PANTHER PTHR24423 285 524 3.5E-49 T 22-04-2016 HRM2_RS12855 37a6952dc4c5c29f2e6be864866e798a 524 PANTHER PTHR24423 157 269 3.5E-49 T 22-04-2016 HRM2_RS12855 37a6952dc4c5c29f2e6be864866e798a 524 PANTHER PTHR24423 6 20 3.5E-49 T 22-04-2016 HRM2_RS12855 37a6952dc4c5c29f2e6be864866e798a 524 SMART SM00448 8 119 1.7E-32 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS12855 37a6952dc4c5c29f2e6be864866e798a 524 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 406 522 5.1E-24 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS12855 37a6952dc4c5c29f2e6be864866e798a 524 Gene3D G3DSA:3.30.450.20 155 256 1.2E-5 T 22-04-2016 HRM2_RS12855 37a6952dc4c5c29f2e6be864866e798a 524 SMART SM00387 405 523 8.9E-28 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS12855 37a6952dc4c5c29f2e6be864866e798a 524 SUPERFAMILY SSF55874 353 521 3.54E-33 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS12855 37a6952dc4c5c29f2e6be864866e798a 524 SUPERFAMILY SSF52172 10 158 1.07E-39 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS22615 f98f44e8462098c186e6c2551ada6c09 299 Gene3D G3DSA:3.40.190.10 123 230 6.9E-22 T 22-04-2016 HRM2_RS22615 f98f44e8462098c186e6c2551ada6c09 299 SMART SM00062 37 270 3.4E-35 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS22615 f98f44e8462098c186e6c2551ada6c09 299 SUPERFAMILY SSF53850 10 268 1.63E-48 T 22-04-2016 HRM2_RS22615 f98f44e8462098c186e6c2551ada6c09 299 Gene3D G3DSA:3.40.190.10 35 122 2.5E-21 T 22-04-2016 HRM2_RS22615 f98f44e8462098c186e6c2551ada6c09 299 Gene3D G3DSA:3.40.190.10 231 269 2.5E-21 T 22-04-2016 HRM2_RS22615 f98f44e8462098c186e6c2551ada6c09 299 PANTHER PTHR30085:SF2 12 269 1.1E-49 T 22-04-2016 HRM2_RS22615 f98f44e8462098c186e6c2551ada6c09 299 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 268 1.4E-41 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS22615 f98f44e8462098c186e6c2551ada6c09 299 PANTHER PTHR30085 12 269 1.1E-49 T 22-04-2016 HRM2_RS20830 da4f6b89f816cc3fe590e29323438180 424 SUPERFAMILY SSF53383 19 422 1.01E-107 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS20830 da4f6b89f816cc3fe590e29323438180 424 Gene3D G3DSA:3.90.1150.10 332 422 3.1E-33 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS20830 da4f6b89f816cc3fe590e29323438180 424 Gene3D G3DSA:3.90.1150.10 20 70 3.1E-33 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS20830 da4f6b89f816cc3fe590e29323438180 424 Gene3D G3DSA:3.40.640.10 71 330 2.2E-71 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS20830 da4f6b89f816cc3fe590e29323438180 424 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 18 421 6.1E-115 T 22-04-2016 IPR010164 Ornithine aminotransferase GO:0008483|GO:0030170 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|UniPathway: UPA00098 HRM2_RS20830 da4f6b89f816cc3fe590e29323438180 424 PANTHER PTHR11986 19 422 1.6E-144 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HRM2_RS20830 da4f6b89f816cc3fe590e29323438180 424 Pfam PF00202 Aminotransferase class-III 28 422 1.4E-104 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HRM2_RS20830 da4f6b89f816cc3fe590e29323438180 424 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 246 283 - T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HRM2_RS21085 6f3b758adfa9f0eb4249067c68e8a1e1 615 SUPERFAMILY SSF52518 208 479 1.59E-62 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS21085 6f3b758adfa9f0eb4249067c68e8a1e1 615 PANTHER PTHR32154:SF13 432 595 4.4E-222 T 22-04-2016 HRM2_RS21085 6f3b758adfa9f0eb4249067c68e8a1e1 615 PANTHER PTHR32154:SF13 1 397 4.4E-222 T 22-04-2016 HRM2_RS21085 6f3b758adfa9f0eb4249067c68e8a1e1 615 PANTHER PTHR32154 432 595 4.4E-222 T 22-04-2016 HRM2_RS21085 6f3b758adfa9f0eb4249067c68e8a1e1 615 PANTHER PTHR32154 1 397 4.4E-222 T 22-04-2016 HRM2_RS21085 6f3b758adfa9f0eb4249067c68e8a1e1 615 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 19 185 6.5E-31 T 22-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HRM2_RS21085 6f3b758adfa9f0eb4249067c68e8a1e1 615 SUPERFAMILY SSF52922 502 607 6.85E-12 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HRM2_RS21085 6f3b758adfa9f0eb4249067c68e8a1e1 615 Gene3D G3DSA:3.40.920.10 11 188 4.3E-22 T 22-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HRM2_RS21085 6f3b758adfa9f0eb4249067c68e8a1e1 615 Gene3D G3DSA:3.40.50.920 502 606 1.9E-6 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HRM2_RS21085 6f3b758adfa9f0eb4249067c68e8a1e1 615 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 9 594 2.3E-166 T 22-04-2016 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969|UniPathway: UPA00223 HRM2_RS21085 6f3b758adfa9f0eb4249067c68e8a1e1 615 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 220 386 1.1E-48 T 22-04-2016 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 HRM2_RS21085 6f3b758adfa9f0eb4249067c68e8a1e1 615 SUPERFAMILY SSF53323 12 227 1.31E-25 T 22-04-2016 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 HRM2_RS21085 6f3b758adfa9f0eb4249067c68e8a1e1 615 Gene3D G3DSA:3.40.50.970 201 403 1.0E-68 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS18345 2518300b4bd8ca3b0a2813a66c149bbe 113 PANTHER PTHR30034:SF1 11 108 1.5E-29 T 22-04-2016 HRM2_RS18345 2518300b4bd8ca3b0a2813a66c149bbe 113 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 33 102 1.1E-25 T 22-04-2016 IPR001543 Surface presentation of antigen (SpoA) HRM2_RS18345 2518300b4bd8ca3b0a2813a66c149bbe 113 PRINTS PR00956 Flagellar motor switch protein FliN signature 78 93 3.85E-27 T 22-04-2016 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 HRM2_RS18345 2518300b4bd8ca3b0a2813a66c149bbe 113 PRINTS PR00956 Flagellar motor switch protein FliN signature 65 78 3.85E-27 T 22-04-2016 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 HRM2_RS18345 2518300b4bd8ca3b0a2813a66c149bbe 113 PRINTS PR00956 Flagellar motor switch protein FliN signature 32 48 3.85E-27 T 22-04-2016 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 HRM2_RS18345 2518300b4bd8ca3b0a2813a66c149bbe 113 PRINTS PR00956 Flagellar motor switch protein FliN signature 49 65 3.85E-27 T 22-04-2016 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 HRM2_RS18345 2518300b4bd8ca3b0a2813a66c149bbe 113 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 30 103 6.0E-33 T 22-04-2016 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 HRM2_RS18345 2518300b4bd8ca3b0a2813a66c149bbe 113 Gene3D G3DSA:2.30.330.10 23 111 3.2E-36 T 22-04-2016 HRM2_RS18345 2518300b4bd8ca3b0a2813a66c149bbe 113 PANTHER PTHR30034 11 108 1.5E-29 T 22-04-2016 HRM2_RS18345 2518300b4bd8ca3b0a2813a66c149bbe 113 SUPERFAMILY SSF101801 29 109 9.02E-25 T 22-04-2016 IPR001543 Surface presentation of antigen (SpoA) HRM2_RS18495 e90b9a596bb777f0e94ddbbbf0de26a5 193 PANTHER PTHR23026 1 180 2.7E-24 T 22-04-2016 HRM2_RS18495 e90b9a596bb777f0e94ddbbbf0de26a5 193 Pfam PF00881 Nitroreductase family 104 154 4.1E-9 T 22-04-2016 IPR029479 Nitroreductase HRM2_RS18495 e90b9a596bb777f0e94ddbbbf0de26a5 193 Pfam PF00881 Nitroreductase family 10 64 4.1E-8 T 22-04-2016 IPR029479 Nitroreductase HRM2_RS18495 e90b9a596bb777f0e94ddbbbf0de26a5 193 Gene3D G3DSA:2.20.180.10 159 192 1.1E-18 T 22-04-2016 IPR023312 Putatuve nitroreductase, C-terminal, bacterial HRM2_RS18495 e90b9a596bb777f0e94ddbbbf0de26a5 193 SUPERFAMILY SSF55469 6 192 3.66E-36 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 HRM2_RS18495 e90b9a596bb777f0e94ddbbbf0de26a5 193 Gene3D G3DSA:3.40.109.10 2 155 1.4E-34 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 HRM2_RS23805 6ddbac742e21336d89102b62764e0698 289 PANTHER PTHR11918:SF47 7 212 2.8E-54 T 22-04-2016 HRM2_RS23805 6ddbac742e21336d89102b62764e0698 289 PANTHER PTHR11918 7 212 2.8E-54 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein HRM2_RS23805 6ddbac742e21336d89102b62764e0698 289 Pfam PF04055 Radical SAM superfamily 21 171 6.4E-12 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS23805 6ddbac742e21336d89102b62764e0698 289 SUPERFAMILY SSF102114 4 238 2.22E-32 T 22-04-2016 HRM2_RS23805 6ddbac742e21336d89102b62764e0698 289 Gene3D G3DSA:3.80.30.20 17 214 8.6E-24 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe HRM2_RS23805 6ddbac742e21336d89102b62764e0698 289 SMART SM00729 15 233 3.5E-25 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS17130 ddf3f98e07f926fde327f681d0195036 295 PANTHER PTHR32332 2 294 3.0E-76 T 22-04-2016 HRM2_RS17130 ddf3f98e07f926fde327f681d0195036 295 SUPERFAMILY SSF51412 2 294 1.14E-55 T 22-04-2016 HRM2_RS17130 ddf3f98e07f926fde327f681d0195036 295 Gene3D G3DSA:3.20.20.70 1 290 2.8E-53 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS17130 ddf3f98e07f926fde327f681d0195036 295 Pfam PF03060 Nitronate monooxygenase 3 294 2.3E-52 T 22-04-2016 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 HRM2_RS16395 937a2ea972d964f2825c904cf874ff4f 371 PRINTS PR00599 Methionine aminopeptidase-1 signature 203 216 7.5E-7 T 22-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase HRM2_RS16395 937a2ea972d964f2825c904cf874ff4f 371 PRINTS PR00599 Methionine aminopeptidase-1 signature 225 241 7.5E-7 T 22-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase HRM2_RS16395 937a2ea972d964f2825c904cf874ff4f 371 PRINTS PR00599 Methionine aminopeptidase-1 signature 323 335 7.5E-7 T 22-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase HRM2_RS16395 937a2ea972d964f2825c904cf874ff4f 371 SUPERFAMILY SSF55920 147 363 3.01E-73 T 22-04-2016 IPR000994 Peptidase M24, structural domain HRM2_RS16395 937a2ea972d964f2825c904cf874ff4f 371 PANTHER PTHR10804 129 365 2.6E-87 T 22-04-2016 HRM2_RS16395 937a2ea972d964f2825c904cf874ff4f 371 Gene3D G3DSA:3.40.350.10 5 141 7.7E-23 T 22-04-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal HRM2_RS16395 937a2ea972d964f2825c904cf874ff4f 371 Gene3D G3DSA:3.90.230.10 146 364 1.7E-75 T 22-04-2016 IPR000994 Peptidase M24, structural domain HRM2_RS16395 937a2ea972d964f2825c904cf874ff4f 371 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 301 313 - T 22-04-2016 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site HRM2_RS16395 937a2ea972d964f2825c904cf874ff4f 371 SUPERFAMILY SSF53092 7 124 5.23E-15 T 22-04-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal HRM2_RS16395 937a2ea972d964f2825c904cf874ff4f 371 Pfam PF01321 Creatinase/Prolidase N-terminal domain 21 143 2.4E-14 T 22-04-2016 IPR000587 Creatinase, N-terminal GO:0016787 HRM2_RS16395 937a2ea972d964f2825c904cf874ff4f 371 PANTHER PTHR10804:SF110 129 365 2.6E-87 T 22-04-2016 HRM2_RS16395 937a2ea972d964f2825c904cf874ff4f 371 Pfam PF00557 Metallopeptidase family M24 154 355 1.3E-66 T 22-04-2016 IPR000994 Peptidase M24, structural domain HRM2_RS09720 9005186ff5d1497741f8f0a1bfff5fab 387 SMART SM00387 270 385 1.4E-27 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS09720 9005186ff5d1497741f8f0a1bfff5fab 387 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 3 111 1.4E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS09720 9005186ff5d1497741f8f0a1bfff5fab 387 PANTHER PTHR24423:SF497 191 387 4.8E-70 T 22-04-2016 HRM2_RS09720 9005186ff5d1497741f8f0a1bfff5fab 387 Gene3D G3DSA:3.30.450.20 2 107 4.3E-8 T 22-04-2016 HRM2_RS09720 9005186ff5d1497741f8f0a1bfff5fab 387 Gene3D G3DSA:3.30.565.10 203 384 2.5E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS09720 9005186ff5d1497741f8f0a1bfff5fab 387 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 272 382 8.1E-20 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS09720 9005186ff5d1497741f8f0a1bfff5fab 387 SUPERFAMILY SSF55785 3 106 3.43E-8 T 22-04-2016 IPR000014 PAS domain HRM2_RS09720 9005186ff5d1497741f8f0a1bfff5fab 387 Pfam PF00512 His Kinase A (phospho-acceptor) domain 138 225 2.4E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS09720 9005186ff5d1497741f8f0a1bfff5fab 387 PRINTS PR00344 Bacterial sensor protein C-terminal signature 345 363 3.9E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS09720 9005186ff5d1497741f8f0a1bfff5fab 387 PRINTS PR00344 Bacterial sensor protein C-terminal signature 314 328 3.9E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS09720 9005186ff5d1497741f8f0a1bfff5fab 387 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 382 3.9E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS09720 9005186ff5d1497741f8f0a1bfff5fab 387 PRINTS PR00344 Bacterial sensor protein C-terminal signature 332 342 3.9E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS09720 9005186ff5d1497741f8f0a1bfff5fab 387 PANTHER PTHR24423 191 387 4.8E-70 T 22-04-2016 HRM2_RS09720 9005186ff5d1497741f8f0a1bfff5fab 387 PANTHER PTHR24423 2 165 4.8E-70 T 22-04-2016 HRM2_RS09720 9005186ff5d1497741f8f0a1bfff5fab 387 Pfam PF08448 PAS fold 6 108 5.8E-6 T 22-04-2016 IPR013656 PAS fold-4 HRM2_RS09720 9005186ff5d1497741f8f0a1bfff5fab 387 PANTHER PTHR24423:SF497 2 165 4.8E-70 T 22-04-2016 HRM2_RS09720 9005186ff5d1497741f8f0a1bfff5fab 387 SUPERFAMILY SSF55874 224 383 4.71E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS13710 cdb29e1be6c2002662b08da546ce3ea2 73 Pfam PF13633 Prokaryotic N-terminal methylation site 13 36 9.1E-12 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site HRM2_RS13710 cdb29e1be6c2002662b08da546ce3ea2 73 PANTHER PTHR30093 1 72 2.4E-21 T 22-04-2016 HRM2_RS13710 cdb29e1be6c2002662b08da546ce3ea2 73 SUPERFAMILY SSF54523 15 72 4.0E-18 T 22-04-2016 HRM2_RS13710 cdb29e1be6c2002662b08da546ce3ea2 73 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 13 35 1.3E-10 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site HRM2_RS13710 cdb29e1be6c2002662b08da546ce3ea2 73 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 13 33 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site HRM2_RS13710 cdb29e1be6c2002662b08da546ce3ea2 73 Gene3D G3DSA:3.30.700.10 15 69 3.4E-17 T 22-04-2016 HRM2_RS02575 6d788e177399309d000e4c0a32cde372 174 Pfam PF00156 Phosphoribosyl transferase domain 33 171 8.7E-21 T 22-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 HRM2_RS02575 6d788e177399309d000e4c0a32cde372 174 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 4 171 36.233 T 22-04-2016 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|UniPathway: UPA00588 HRM2_RS02575 6d788e177399309d000e4c0a32cde372 174 SUPERFAMILY SSF53271 7 168 4.85E-49 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like HRM2_RS02575 6d788e177399309d000e4c0a32cde372 174 PANTHER PTHR32315 1 174 2.3E-85 T 22-04-2016 HRM2_RS02575 6d788e177399309d000e4c0a32cde372 174 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 4 169 3.3E-68 T 22-04-2016 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|UniPathway: UPA00588 HRM2_RS02575 6d788e177399309d000e4c0a32cde372 174 Gene3D G3DSA:3.40.50.2020 3 171 6.1E-68 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like HRM2_RS18120 563225fa8ce7fb0d3a7cc50bfb0d6d51 386 SUPERFAMILY SSF53383 10 384 1.38E-122 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS18120 563225fa8ce7fb0d3a7cc50bfb0d6d51 386 PANTHER PTHR30244 2 385 2.2E-142 T 22-04-2016 HRM2_RS18120 563225fa8ce7fb0d3a7cc50bfb0d6d51 386 Gene3D G3DSA:3.40.640.10 11 257 1.8E-90 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS18120 563225fa8ce7fb0d3a7cc50bfb0d6d51 386 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 18 378 1.0E-129 T 22-04-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase HRM2_RS18120 563225fa8ce7fb0d3a7cc50bfb0d6d51 386 TIGRFAM TIGR03588 PseC: UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase 11 380 6.9E-142 T 22-04-2016 IPR020026 UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase HRM2_RS18120 563225fa8ce7fb0d3a7cc50bfb0d6d51 386 PIRSF PIRSF000390 6 386 1.1E-125 T 22-04-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase HRM2_RS18120 563225fa8ce7fb0d3a7cc50bfb0d6d51 386 Gene3D G3DSA:3.90.1150.10 259 384 2.5E-35 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS18120 563225fa8ce7fb0d3a7cc50bfb0d6d51 386 PANTHER PTHR30244:SF3 2 385 2.2E-142 T 22-04-2016 HRM2_RS18830 99c798c91550ae650a9faaefce9659e1 880 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 143 451 2.3E-83 T 22-04-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 HRM2_RS18830 99c798c91550ae650a9faaefce9659e1 880 PANTHER PTHR22931:SF7 59 611 1.9E-92 T 22-04-2016 HRM2_RS18830 99c798c91550ae650a9faaefce9659e1 880 SUPERFAMILY SSF52009 458 568 3.92E-23 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS18830 99c798c91550ae650a9faaefce9659e1 880 PANTHER PTHR22931 59 611 1.9E-92 T 22-04-2016 HRM2_RS18830 99c798c91550ae650a9faaefce9659e1 880 Pfam PF00391 PEP-utilising enzyme, mobile domain 492 561 2.8E-17 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS18830 99c798c91550ae650a9faaefce9659e1 880 SUPERFAMILY SSF56059 128 481 1.14E-69 T 22-04-2016 HRM2_RS18830 99c798c91550ae650a9faaefce9659e1 880 Gene3D G3DSA:3.50.30.10 486 576 5.4E-22 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS18830 99c798c91550ae650a9faaefce9659e1 880 Gene3D G3DSA:3.30.470.20 315 448 6.4E-36 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS18830 99c798c91550ae650a9faaefce9659e1 880 Gene3D G3DSA:3.30.1490.20 129 314 3.8E-54 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HRM2_RS21860 eed4feb0a9bfbd4e41d8c71118f2ef92 123 Pfam PF01807 CHC2 zinc finger 10 91 3.9E-6 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS21860 eed4feb0a9bfbd4e41d8c71118f2ef92 123 Gene3D G3DSA:3.90.580.10 5 99 4.4E-13 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS21860 eed4feb0a9bfbd4e41d8c71118f2ef92 123 SUPERFAMILY SSF57783 13 92 2.72E-10 T 22-04-2016 HRM2_RS08990 fe9271dca93e6b95695fcb75859a5678 437 PRINTS PR00415 Aconitase family signature 360 373 5.6E-27 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS08990 fe9271dca93e6b95695fcb75859a5678 437 PRINTS PR00415 Aconitase family signature 304 315 5.6E-27 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS08990 fe9271dca93e6b95695fcb75859a5678 437 PRINTS PR00415 Aconitase family signature 112 125 5.6E-27 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS08990 fe9271dca93e6b95695fcb75859a5678 437 PRINTS PR00415 Aconitase family signature 202 215 5.6E-27 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS08990 fe9271dca93e6b95695fcb75859a5678 437 PRINTS PR00415 Aconitase family signature 126 141 5.6E-27 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS08990 fe9271dca93e6b95695fcb75859a5678 437 PRINTS PR00415 Aconitase family signature 101 109 5.6E-27 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS08990 fe9271dca93e6b95695fcb75859a5678 437 PRINTS PR00415 Aconitase family signature 188 201 5.6E-27 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS08990 fe9271dca93e6b95695fcb75859a5678 437 Gene3D G3DSA:3.30.499.10 2 156 4.1E-28 T 22-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS08990 fe9271dca93e6b95695fcb75859a5678 437 PANTHER PTHR11670 1 421 3.4E-165 T 22-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS08990 fe9271dca93e6b95695fcb75859a5678 437 Pfam PF00330 Aconitase family (aconitate hydratase) 7 418 2.6E-104 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS08990 fe9271dca93e6b95695fcb75859a5678 437 Gene3D G3DSA:3.30.499.10 284 424 6.7E-57 T 22-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS08990 fe9271dca93e6b95695fcb75859a5678 437 ProSitePatterns PS00450 Aconitase family signature 1. 300 316 - T 22-04-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS08990 fe9271dca93e6b95695fcb75859a5678 437 TIGRFAM TIGR02086 IPMI_arch: 3-isopropylmalate dehydratase, large subunit 3 423 4.2E-134 T 22-04-2016 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS08990 fe9271dca93e6b95695fcb75859a5678 437 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 4 423 7.0E-148 T 22-04-2016 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS08990 fe9271dca93e6b95695fcb75859a5678 437 ProSitePatterns PS01244 Aconitase family signature 2. 360 373 - T 22-04-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS08990 fe9271dca93e6b95695fcb75859a5678 437 SUPERFAMILY SSF53732 1 425 1.26E-140 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS08990 fe9271dca93e6b95695fcb75859a5678 437 Gene3D G3DSA:3.40.1060.10 159 273 3.6E-34 T 22-04-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS08990 fe9271dca93e6b95695fcb75859a5678 437 Hamap MF_01027 3-isopropylmalate dehydratase large subunit [leuC]. 3 426 42.431 T 22-04-2016 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS13285 38e65575024bb64de12241d6e338362b 1238 Pfam PF01380 SIS domain 652 726 4.2E-12 T 22-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 HRM2_RS13285 38e65575024bb64de12241d6e338362b 1238 Gene3D G3DSA:3.40.50.10490 535 754 9.8E-37 T 22-04-2016 HRM2_RS13285 38e65575024bb64de12241d6e338362b 1238 Gene3D G3DSA:3.40.50.10490 755 925 6.4E-13 T 22-04-2016 HRM2_RS13285 38e65575024bb64de12241d6e338362b 1238 SUPERFAMILY SSF53697 537 905 1.11E-42 T 22-04-2016 HRM2_RS13285 38e65575024bb64de12241d6e338362b 1238 SUPERFAMILY SSF56235 215 238 4.42E-25 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal HRM2_RS13285 38e65575024bb64de12241d6e338362b 1238 SUPERFAMILY SSF56235 305 487 4.42E-25 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal HRM2_RS13285 38e65575024bb64de12241d6e338362b 1238 Gene3D G3DSA:3.60.20.10 306 487 4.4E-30 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal HRM2_RS13285 38e65575024bb64de12241d6e338362b 1238 Gene3D G3DSA:3.60.20.10 215 240 4.4E-30 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal HRM2_RS13285 38e65575024bb64de12241d6e338362b 1238 PANTHER PTHR10937 214 281 1.4E-65 T 22-04-2016 HRM2_RS13285 38e65575024bb64de12241d6e338362b 1238 PANTHER PTHR10937 338 903 1.4E-65 T 22-04-2016 HRM2_RS13285 38e65575024bb64de12241d6e338362b 1238 Pfam PF13522 Glutamine amidotransferase domain 333 472 6.1E-9 T 22-04-2016 HRM2_RS13285 38e65575024bb64de12241d6e338362b 1238 PANTHER PTHR10937:SF0 214 281 1.4E-65 T 22-04-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 HRM2_RS13285 38e65575024bb64de12241d6e338362b 1238 PANTHER PTHR10937:SF0 338 903 1.4E-65 T 22-04-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 HRM2_RS06515 027df678085f5e4fda21f610c4c5e4cf 137 Pfam PF04965 Gene 25-like lysozyme 31 118 4.3E-22 T 22-04-2016 IPR007048 GpW/Gp25/anti-adapter protein IraD HRM2_RS06515 027df678085f5e4fda21f610c4c5e4cf 137 Gene3D G3DSA:3.10.450.40 2 132 4.5E-38 T 22-04-2016 HRM2_RS06515 027df678085f5e4fda21f610c4c5e4cf 137 PANTHER PTHR35862 1 131 2.3E-25 T 22-04-2016 HRM2_RS06515 027df678085f5e4fda21f610c4c5e4cf 137 PANTHER PTHR35862:SF2 1 131 2.3E-25 T 22-04-2016 HRM2_RS06515 027df678085f5e4fda21f610c4c5e4cf 137 SUPERFAMILY SSF160719 30 132 2.62E-27 T 22-04-2016 HRM2_RS09690 1a66e907bca4e7da9b63e8ad05b9423f 231 PANTHER PTHR30399 3 222 4.1E-30 T 22-04-2016 HRM2_RS09690 1a66e907bca4e7da9b63e8ad05b9423f 231 Pfam PF01863 Protein of unknown function DUF45 22 225 1.1E-47 T 22-04-2016 IPR002725 Protein of unknown function DUF45 HRM2_RS00215 5abf87f8f05e67d058fc263ceaa11ca4 518 Pfam PF02321 Outer membrane efflux protein 129 300 1.1E-6 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS00215 5abf87f8f05e67d058fc263ceaa11ca4 518 Pfam PF02321 Outer membrane efflux protein 412 515 4.5E-7 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS00215 5abf87f8f05e67d058fc263ceaa11ca4 518 Gene3D G3DSA:1.20.1600.10 127 515 8.6E-23 T 22-04-2016 HRM2_RS00215 5abf87f8f05e67d058fc263ceaa11ca4 518 SUPERFAMILY SSF56954 123 515 5.1E-29 T 22-04-2016 HRM2_RS00215 5abf87f8f05e67d058fc263ceaa11ca4 518 PANTHER PTHR30026 199 515 8.0E-12 T 22-04-2016 HRM2_RS18960 f78937d84a04e67988dd5c1606ae65ad 354 Pfam PF01544 CorA-like Mg2+ transporter protein 60 350 3.8E-70 T 22-04-2016 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 HRM2_RS18960 f78937d84a04e67988dd5c1606ae65ad 354 SUPERFAMILY SSF144083 289 352 2.09E-21 T 22-04-2016 HRM2_RS18960 f78937d84a04e67988dd5c1606ae65ad 354 PANTHER PTHR21535 54 354 4.9E-73 T 22-04-2016 HRM2_RS18960 f78937d84a04e67988dd5c1606ae65ad 354 Gene3D G3DSA:1.20.58.340 164 276 2.6E-32 T 22-04-2016 HRM2_RS18960 f78937d84a04e67988dd5c1606ae65ad 354 Gene3D G3DSA:1.20.58.340 278 354 1.1E-30 T 22-04-2016 HRM2_RS18960 f78937d84a04e67988dd5c1606ae65ad 354 PANTHER PTHR21535:SF33 54 354 4.9E-73 T 22-04-2016 HRM2_RS18960 f78937d84a04e67988dd5c1606ae65ad 354 Gene3D G3DSA:3.30.460.20 4 163 4.5E-47 T 22-04-2016 HRM2_RS18960 f78937d84a04e67988dd5c1606ae65ad 354 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 41 354 2.1E-88 T 22-04-2016 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 HRM2_RS18960 f78937d84a04e67988dd5c1606ae65ad 354 SUPERFAMILY SSF143865 13 287 1.22E-71 T 22-04-2016 HRM2_RS11720 c713c9e47080f8bdb9bd269c518a307c 1434 Pfam PF12439 Glycogen debranching enzyme N terminal 779 1003 1.2E-26 T 22-04-2016 IPR024742 Glycogen debranching enzyme, bacterial and archaeal type, N-terminal HRM2_RS11720 c713c9e47080f8bdb9bd269c518a307c 1434 SUPERFAMILY SSF51445 131 494 5.6E-51 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily HRM2_RS11720 c713c9e47080f8bdb9bd269c518a307c 1434 PANTHER PTHR10569 1057 1312 4.2E-32 T 22-04-2016 IPR010401 Glycogen debranching enzyme GO:0004134|GO:0004135|GO:0005980 KEGG: 00500+3.2.1.33+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 HRM2_RS11720 c713c9e47080f8bdb9bd269c518a307c 1434 PANTHER PTHR10569 1331 1427 4.2E-32 T 22-04-2016 IPR010401 Glycogen debranching enzyme GO:0004134|GO:0004135|GO:0005980 KEGG: 00500+3.2.1.33+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 HRM2_RS11720 c713c9e47080f8bdb9bd269c518a307c 1434 Pfam PF06202 Amylo-alpha-1,6-glucosidase 1053 1425 2.1E-57 T 22-04-2016 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25+3.2.1.33|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 HRM2_RS11720 c713c9e47080f8bdb9bd269c518a307c 1434 Pfam PF00128 Alpha amylase, catalytic domain 296 378 2.6E-4 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HRM2_RS11720 c713c9e47080f8bdb9bd269c518a307c 1434 SMART SM00642 167 482 3.8E-5 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HRM2_RS11720 c713c9e47080f8bdb9bd269c518a307c 1434 SUPERFAMILY SSF48208 963 1004 3.16E-39 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 HRM2_RS11720 c713c9e47080f8bdb9bd269c518a307c 1434 SUPERFAMILY SSF48208 1349 1429 3.16E-39 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 HRM2_RS11720 c713c9e47080f8bdb9bd269c518a307c 1434 SUPERFAMILY SSF48208 1037 1312 3.16E-39 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 HRM2_RS11720 c713c9e47080f8bdb9bd269c518a307c 1434 Gene3D G3DSA:3.20.20.80 129 492 7.2E-48 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HRM2_RS07235 19db4bf88a08623f1941c363123b215b 206 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 1 194 3.3E-30 T 22-04-2016 HRM2_RS07235 19db4bf88a08623f1941c363123b215b 206 PANTHER PTHR42208 1 205 4.0E-16 T 22-04-2016 HRM2_RS07235 19db4bf88a08623f1941c363123b215b 206 PANTHER PTHR42208:SF1 1 205 4.0E-16 T 22-04-2016 HRM2_RS10375 80ab3688b6f419f7817b769b34da4540 514 SUPERFAMILY SSF110921 395 500 2.09E-22 T 22-04-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 HRM2_RS10375 80ab3688b6f419f7817b769b34da4540 514 SMART SM00917 371 501 7.2E-30 T 22-04-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 HRM2_RS10375 80ab3688b6f419f7817b769b34da4540 514 Pfam PF08502 LeuA allosteric (dimerisation) domain 372 500 5.7E-30 T 22-04-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 HRM2_RS10375 80ab3688b6f419f7817b769b34da4540 514 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 4 510 42.098 T 22-04-2016 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 HRM2_RS10375 80ab3688b6f419f7817b769b34da4540 514 SUPERFAMILY SSF51569 3 293 1.83E-98 T 22-04-2016 HRM2_RS10375 80ab3688b6f419f7817b769b34da4540 514 PANTHER PTHR10277 1 509 4.7E-244 T 22-04-2016 HRM2_RS10375 80ab3688b6f419f7817b769b34da4540 514 Pfam PF00682 HMGL-like 6 275 8.4E-95 T 22-04-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 HRM2_RS10375 80ab3688b6f419f7817b769b34da4540 514 Gene3D G3DSA:3.20.20.70 2 348 5.3E-147 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS10375 80ab3688b6f419f7817b769b34da4540 514 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 201 214 - T 22-04-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 HRM2_RS10375 80ab3688b6f419f7817b769b34da4540 514 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 14 30 - T 22-04-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 HRM2_RS10375 80ab3688b6f419f7817b769b34da4540 514 PANTHER PTHR10277:SF9 1 509 4.7E-244 T 22-04-2016 HRM2_RS10375 80ab3688b6f419f7817b769b34da4540 514 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 6 498 7.5E-213 T 22-04-2016 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 HRM2_RS18335 5221e13ada0598c0c0a1248d918cebcb 258 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 116 128 1.3E-19 T 22-04-2016 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HRM2_RS18335 5221e13ada0598c0c0a1248d918cebcb 258 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 246 256 1.3E-19 T 22-04-2016 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HRM2_RS18335 5221e13ada0598c0c0a1248d918cebcb 258 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 56 65 1.3E-19 T 22-04-2016 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HRM2_RS18335 5221e13ada0598c0c0a1248d918cebcb 258 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 178 190 1.3E-19 T 22-04-2016 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HRM2_RS18335 5221e13ada0598c0c0a1248d918cebcb 258 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 128 142 1.3E-19 T 22-04-2016 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HRM2_RS18335 5221e13ada0598c0c0a1248d918cebcb 258 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 156 168 1.3E-19 T 22-04-2016 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HRM2_RS18335 5221e13ada0598c0c0a1248d918cebcb 258 Pfam PF00813 FliP family 60 252 2.3E-77 T 22-04-2016 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HRM2_RS18335 5221e13ada0598c0c0a1248d918cebcb 258 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 77 97 2.8E-64 T 22-04-2016 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HRM2_RS18335 5221e13ada0598c0c0a1248d918cebcb 258 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 58 77 2.8E-64 T 22-04-2016 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HRM2_RS18335 5221e13ada0598c0c0a1248d918cebcb 258 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 206 227 2.8E-64 T 22-04-2016 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HRM2_RS18335 5221e13ada0598c0c0a1248d918cebcb 258 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 185 205 2.8E-64 T 22-04-2016 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HRM2_RS18335 5221e13ada0598c0c0a1248d918cebcb 258 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 97 116 2.8E-64 T 22-04-2016 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HRM2_RS18335 5221e13ada0598c0c0a1248d918cebcb 258 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 230 255 2.8E-64 T 22-04-2016 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HRM2_RS18335 5221e13ada0598c0c0a1248d918cebcb 258 PANTHER PTHR30587:SF0 18 258 8.1E-113 T 22-04-2016 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HRM2_RS18335 5221e13ada0598c0c0a1248d918cebcb 258 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 233 245 - T 22-04-2016 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HRM2_RS18335 5221e13ada0598c0c0a1248d918cebcb 258 PANTHER PTHR30587 18 258 8.1E-113 T 22-04-2016 HRM2_RS18335 5221e13ada0598c0c0a1248d918cebcb 258 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 60 256 3.9E-83 T 22-04-2016 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 Pfam PF00580 UvrD/REP helicase N-terminal domain 7 444 6.2E-56 T 22-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 PANTHER PTHR11070 528 794 2.7E-292 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 PANTHER PTHR11070 307 501 2.7E-292 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 PANTHER PTHR11070 816 1228 2.7E-292 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 PANTHER PTHR11070 1 86 2.7E-292 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 PANTHER PTHR11070 117 204 2.7E-292 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 SUPERFAMILY SSF52540 117 172 3.19E-97 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 SUPERFAMILY SSF52540 334 479 3.19E-97 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 SUPERFAMILY SSF52540 533 785 3.19E-97 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 SUPERFAMILY SSF52540 6 77 3.19E-97 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 SUPERFAMILY SSF52540 817 836 3.19E-97 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 Gene3D G3DSA:3.40.50.300 6 79 1.1E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 Gene3D G3DSA:3.40.50.300 119 149 1.1E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 Gene3D G3DSA:3.40.50.300 360 458 1.1E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 Hamap MF_01485 RecBCD enzyme subunit RecB [recB]. 2 1233 14.479 T 22-04-2016 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 TIGRFAM TIGR00609 recB: exodeoxyribonuclease V, beta subunit 5 1231 0.0 T 22-04-2016 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 Gene3D G3DSA:3.90.320.10 913 1235 1.9E-88 T 22-04-2016 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 Gene3D G3DSA:1.10.486.10 601 745 6.3E-45 T 22-04-2016 HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 Gene3D G3DSA:3.40.50.300 459 598 1.1E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 Gene3D G3DSA:3.40.50.300 746 872 1.1E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 SUPERFAMILY SSF52980 922 936 5.25E-75 T 22-04-2016 IPR011335 Restriction endonuclease type II-like HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 SUPERFAMILY SSF52980 968 1234 5.25E-75 T 22-04-2016 IPR011335 Restriction endonuclease type II-like HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 PANTHER PTHR11070:SF23 528 794 2.7E-292 T 22-04-2016 HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 PANTHER PTHR11070:SF23 307 501 2.7E-292 T 22-04-2016 HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 PANTHER PTHR11070:SF23 816 1228 2.7E-292 T 22-04-2016 HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 PANTHER PTHR11070:SF23 1 86 2.7E-292 T 22-04-2016 HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 PANTHER PTHR11070:SF23 117 204 2.7E-292 T 22-04-2016 HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 Pfam PF13361 UvrD-like helicase C-terminal domain 740 831 7.5E-11 T 22-04-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 HRM2_RS13115 023d85e5bd6724bcc4673cf3e744fe6f 1242 Gene3D G3DSA:1.10.3170.10 155 358 5.9E-41 T 22-04-2016 HRM2_RS20795 6bf5d9bb393466692f14a1dece0222c8 232 PANTHER PTHR31272 1 229 7.3E-78 T 22-04-2016 HRM2_RS20795 6bf5d9bb393466692f14a1dece0222c8 232 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 11 223 2.1E-62 T 22-04-2016 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 HRM2_RS20795 6bf5d9bb393466692f14a1dece0222c8 232 PANTHER PTHR31272:SF4 1 229 7.3E-78 T 22-04-2016 HRM2_RS06975 7cb1b915740df8217d75364928aea746 106 SUPERFAMILY SSF54909 5 97 4.54E-17 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel HRM2_RS06975 7cb1b915740df8217d75364928aea746 106 Pfam PF03992 Antibiotic biosynthesis monooxygenase 30 72 1.7E-6 T 22-04-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain HRM2_RS06975 7cb1b915740df8217d75364928aea746 106 Gene3D G3DSA:3.30.70.900 15 87 1.4E-10 T 22-04-2016 HRM2_RS24110 39f0b6af80fb1d3dfbc9fa1c91f77edd 254 SUPERFAMILY SSF52540 2 249 3.15E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24110 39f0b6af80fb1d3dfbc9fa1c91f77edd 254 Gene3D G3DSA:3.40.50.300 2 247 4.6E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24110 39f0b6af80fb1d3dfbc9fa1c91f77edd 254 PANTHER PTHR24220:SF358 117 251 2.4E-96 T 22-04-2016 HRM2_RS24110 39f0b6af80fb1d3dfbc9fa1c91f77edd 254 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS24110 39f0b6af80fb1d3dfbc9fa1c91f77edd 254 SMART SM00382 26 215 1.0E-4 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS24110 39f0b6af80fb1d3dfbc9fa1c91f77edd 254 PANTHER PTHR24220 117 251 2.4E-96 T 22-04-2016 HRM2_RS24110 39f0b6af80fb1d3dfbc9fa1c91f77edd 254 PANTHER PTHR24220 3 101 2.4E-96 T 22-04-2016 HRM2_RS24110 39f0b6af80fb1d3dfbc9fa1c91f77edd 254 PANTHER PTHR24220:SF358 3 101 2.4E-96 T 22-04-2016 HRM2_RS24110 39f0b6af80fb1d3dfbc9fa1c91f77edd 254 Pfam PF00005 ABC transporter 18 178 7.3E-25 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS24110 39f0b6af80fb1d3dfbc9fa1c91f77edd 254 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 227 248 4.1E-9 T 22-04-2016 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal HRM2_RS04295 6feb747c73f869312630ed2dc6654ac4 520 Gene3D G3DSA:2.30.38.10 345 420 1.9E-20 T 22-04-2016 HRM2_RS04295 6feb747c73f869312630ed2dc6654ac4 520 Pfam PF13193 AMP-binding enzyme C-terminal domain 435 510 1.6E-24 T 22-04-2016 IPR025110 AMP-binding enzyme C-terminal domain HRM2_RS04295 6feb747c73f869312630ed2dc6654ac4 520 Gene3D G3DSA:3.40.50.980 177 326 1.9E-43 T 22-04-2016 HRM2_RS04295 6feb747c73f869312630ed2dc6654ac4 520 Gene3D G3DSA:3.30.300.30 421 518 6.3E-33 T 22-04-2016 HRM2_RS04295 6feb747c73f869312630ed2dc6654ac4 520 Gene3D G3DSA:3.40.50.980 6 176 8.0E-33 T 22-04-2016 HRM2_RS04295 6feb747c73f869312630ed2dc6654ac4 520 SUPERFAMILY SSF56801 5 518 7.33E-142 T 22-04-2016 HRM2_RS04295 6feb747c73f869312630ed2dc6654ac4 520 PANTHER PTHR24095 6 519 2.9E-158 T 22-04-2016 HRM2_RS04295 6feb747c73f869312630ed2dc6654ac4 520 Pfam PF00501 AMP-binding enzyme 12 426 2.1E-88 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS17800 025899444876941de9879e0b9d93d526 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 2.2E-38 T 22-04-2016 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 HRM2_RS17800 025899444876941de9879e0b9d93d526 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 27.423 T 22-04-2016 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 HRM2_RS17800 025899444876941de9879e0b9d93d526 72 SMART SM00316 4 72 7.2E-6 T 22-04-2016 IPR022967 RNA-binding domain, S1 HRM2_RS17800 025899444876941de9879e0b9d93d526 72 PANTHER PTHR33370 1 72 3.1E-47 T 22-04-2016 HRM2_RS17800 025899444876941de9879e0b9d93d526 72 Pfam PF01176 Translation initiation factor 1A / IF-1 8 70 5.0E-28 T 22-04-2016 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 HRM2_RS17800 025899444876941de9879e0b9d93d526 72 Gene3D G3DSA:2.40.50.140 1 72 1.0E-39 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS17800 025899444876941de9879e0b9d93d526 72 SUPERFAMILY SSF50249 1 71 9.55E-29 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS01430 d984536835003da0e18e849ca9f66fb2 644 SMART SM00926 1 55 1.1E-10 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS01430 d984536835003da0e18e849ca9f66fb2 644 PANTHER PTHR11615:SF127 5 637 2.3E-71 T 22-04-2016 HRM2_RS01430 d984536835003da0e18e849ca9f66fb2 644 Gene3D G3DSA:3.40.50.740 60 130 2.3E-43 T 22-04-2016 HRM2_RS01430 d984536835003da0e18e849ca9f66fb2 644 Gene3D G3DSA:3.40.50.740 318 519 2.3E-43 T 22-04-2016 HRM2_RS01430 d984536835003da0e18e849ca9f66fb2 644 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 5 54 2.7E-7 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS01430 d984536835003da0e18e849ca9f66fb2 644 Gene3D G3DSA:2.20.25.90 5 59 6.9E-11 T 22-04-2016 HRM2_RS01430 d984536835003da0e18e849ca9f66fb2 644 Gene3D G3DSA:2.40.40.20 532 642 4.4E-5 T 22-04-2016 HRM2_RS01430 d984536835003da0e18e849ca9f66fb2 644 PANTHER PTHR11615 5 637 2.3E-71 T 22-04-2016 HRM2_RS01430 d984536835003da0e18e849ca9f66fb2 644 Pfam PF00384 Molybdopterin oxidoreductase 58 456 2.0E-31 T 22-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 HRM2_RS01430 d984536835003da0e18e849ca9f66fb2 644 SUPERFAMILY SSF53706 5 536 2.88E-94 T 22-04-2016 HRM2_RS01430 d984536835003da0e18e849ca9f66fb2 644 SUPERFAMILY SSF50692 527 643 1.22E-7 T 22-04-2016 IPR009010 Aspartate decarboxylase-like domain HRM2_RS01430 d984536835003da0e18e849ca9f66fb2 644 Gene3D G3DSA:3.40.228.10 131 317 3.2E-23 T 22-04-2016 HRM2_RS14990 36bb3dd74c9e94f7dbb92c986230e97a 155 Gene3D G3DSA:3.10.50.30 76 154 2.6E-28 T 22-04-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 HRM2_RS14990 36bb3dd74c9e94f7dbb92c986230e97a 155 Pfam PF03449 Transcription elongation factor, N-terminal 4 74 5.5E-29 T 22-04-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 HRM2_RS14990 36bb3dd74c9e94f7dbb92c986230e97a 155 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 120 136 - T 22-04-2016 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 HRM2_RS14990 36bb3dd74c9e94f7dbb92c986230e97a 155 PANTHER PTHR30437 2 155 1.5E-58 T 22-04-2016 HRM2_RS14990 36bb3dd74c9e94f7dbb92c986230e97a 155 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 154 4.9E-55 T 22-04-2016 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 HRM2_RS14990 36bb3dd74c9e94f7dbb92c986230e97a 155 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 81 154 1.8E-27 T 22-04-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 HRM2_RS14990 36bb3dd74c9e94f7dbb92c986230e97a 155 SUPERFAMILY SSF46557 3 77 3.53E-26 T 22-04-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 HRM2_RS14990 36bb3dd74c9e94f7dbb92c986230e97a 155 PIRSF PIRSF006092 2 155 5.8E-49 T 22-04-2016 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 HRM2_RS14990 36bb3dd74c9e94f7dbb92c986230e97a 155 Gene3D G3DSA:1.10.287.180 3 75 2.2E-30 T 22-04-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 HRM2_RS14990 36bb3dd74c9e94f7dbb92c986230e97a 155 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 155 30.542 T 22-04-2016 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 HRM2_RS14990 36bb3dd74c9e94f7dbb92c986230e97a 155 SUPERFAMILY SSF54534 80 154 4.97E-22 T 22-04-2016 HRM2_RS19925 9d8c0d370c12d2178301d59d077f4dc7 256 PANTHER PTHR30028:SF0 6 256 7.7E-60 T 22-04-2016 IPR005226 UPF0014 family HRM2_RS19925 9d8c0d370c12d2178301d59d077f4dc7 256 PANTHER PTHR30028 6 256 7.7E-60 T 22-04-2016 HRM2_RS19925 9d8c0d370c12d2178301d59d077f4dc7 256 Pfam PF03649 Uncharacterised protein family (UPF0014) 10 245 1.0E-59 T 22-04-2016 IPR005226 UPF0014 family HRM2_RS17875 8cbd042be05c2c13e7909b11f03aab90 111 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 27.711 T 22-04-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 HRM2_RS17875 8cbd042be05c2c13e7909b11f03aab90 111 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 6 107 3.9E-40 T 22-04-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 HRM2_RS17875 8cbd042be05c2c13e7909b11f03aab90 111 PANTHER PTHR13501 1 107 1.1E-41 T 22-04-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 HRM2_RS17875 8cbd042be05c2c13e7909b11f03aab90 111 Gene3D G3DSA:3.90.470.10 1 108 2.0E-39 T 22-04-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17875 8cbd042be05c2c13e7909b11f03aab90 111 SUPERFAMILY SSF54843 1 108 1.83E-40 T 22-04-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17875 8cbd042be05c2c13e7909b11f03aab90 111 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 22-04-2016 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17875 8cbd042be05c2c13e7909b11f03aab90 111 Pfam PF00237 Ribosomal protein L22p/L17e 8 107 3.8E-30 T 22-04-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 HRM2_RS16335 d01c976ea6bc5cff58eda84dfafba264 159 SUPERFAMILY SSF55729 1 157 5.22E-24 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS16335 d01c976ea6bc5cff58eda84dfafba264 159 Pfam PF13673 Acetyltransferase (GNAT) domain 37 144 4.4E-12 T 22-04-2016 IPR000182 GNAT domain GO:0008080 HRM2_RS16335 d01c976ea6bc5cff58eda84dfafba264 159 PANTHER PTHR23091:SF236 1 159 8.1E-20 T 22-04-2016 HRM2_RS16335 d01c976ea6bc5cff58eda84dfafba264 159 Gene3D G3DSA:3.40.630.30 1 149 1.1E-22 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS16335 d01c976ea6bc5cff58eda84dfafba264 159 PANTHER PTHR23091 1 159 8.1E-20 T 22-04-2016 HRM2_RS17425 daf3d24f1c74c7607af2ddc318640e8c 301 SUPERFAMILY SSF52317 6 162 1.05E-39 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS17425 daf3d24f1c74c7607af2ddc318640e8c 301 PANTHER PTHR30237:SF2 6 300 6.4E-77 T 22-04-2016 HRM2_RS17425 daf3d24f1c74c7607af2ddc318640e8c 301 Gene3D G3DSA:3.40.50.10740 7 157 1.6E-45 T 22-04-2016 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain HRM2_RS17425 daf3d24f1c74c7607af2ddc318640e8c 301 Pfam PF02016 LD-carboxypeptidase 17 283 7.0E-70 T 22-04-2016 IPR003507 Peptidase family S66 HRM2_RS17425 daf3d24f1c74c7607af2ddc318640e8c 301 PANTHER PTHR30237 6 300 6.4E-77 T 22-04-2016 HRM2_RS17425 daf3d24f1c74c7607af2ddc318640e8c 301 SUPERFAMILY SSF141986 146 292 4.45E-40 T 22-04-2016 IPR027461 LD-carboxypeptidase A, C-terminal domain HRM2_RS17425 daf3d24f1c74c7607af2ddc318640e8c 301 Gene3D G3DSA:3.50.30.60 167 293 1.2E-40 T 22-04-2016 IPR027461 LD-carboxypeptidase A, C-terminal domain HRM2_RS17425 daf3d24f1c74c7607af2ddc318640e8c 301 PIRSF PIRSF028757 7 299 1.6E-78 T 22-04-2016 IPR003507 Peptidase family S66 HRM2_RS03485 0359f6356cbc30ac5757c2524d58936f 126 Gene3D G3DSA:3.40.50.2300 3 122 8.2E-35 T 22-04-2016 HRM2_RS03485 0359f6356cbc30ac5757c2524d58936f 126 SUPERFAMILY SSF52172 4 121 6.83E-35 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS03485 0359f6356cbc30ac5757c2524d58936f 126 SMART SM00448 6 117 4.0E-32 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS03485 0359f6356cbc30ac5757c2524d58936f 126 PANTHER PTHR26402 6 120 1.0E-35 T 22-04-2016 HRM2_RS03485 0359f6356cbc30ac5757c2524d58936f 126 Pfam PF00072 Response regulator receiver domain 8 117 2.3E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18100 788deee00976c1e79f3f79c334dc5094 455 Pfam PF02080 TrkA-C domain 382 448 1.2E-10 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS18100 788deee00976c1e79f3f79c334dc5094 455 Pfam PF02080 TrkA-C domain 156 224 5.6E-10 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS18100 788deee00976c1e79f3f79c334dc5094 455 PANTHER PTHR13789 1 452 5.4E-34 T 22-04-2016 HRM2_RS18100 788deee00976c1e79f3f79c334dc5094 455 Pfam PF02254 TrkA-N domain 235 351 2.7E-21 T 22-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 HRM2_RS18100 788deee00976c1e79f3f79c334dc5094 455 Pfam PF02254 TrkA-N domain 3 124 2.2E-25 T 22-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 HRM2_RS18100 788deee00976c1e79f3f79c334dc5094 455 Gene3D G3DSA:3.40.50.720 2 151 1.6E-39 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS18100 788deee00976c1e79f3f79c334dc5094 455 Gene3D G3DSA:3.40.50.720 233 375 4.1E-34 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS18100 788deee00976c1e79f3f79c334dc5094 455 SUPERFAMILY SSF51735 233 372 3.07E-29 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS18100 788deee00976c1e79f3f79c334dc5094 455 SUPERFAMILY SSF116726 135 224 5.62E-12 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS18100 788deee00976c1e79f3f79c334dc5094 455 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 9.7E-18 T 22-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 HRM2_RS18100 788deee00976c1e79f3f79c334dc5094 455 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 9.7E-18 T 22-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 HRM2_RS18100 788deee00976c1e79f3f79c334dc5094 455 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 9.7E-18 T 22-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 HRM2_RS18100 788deee00976c1e79f3f79c334dc5094 455 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 9.7E-18 T 22-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 HRM2_RS18100 788deee00976c1e79f3f79c334dc5094 455 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 9.7E-18 T 22-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 HRM2_RS18100 788deee00976c1e79f3f79c334dc5094 455 PANTHER PTHR13789:SF225 1 452 5.4E-34 T 22-04-2016 HRM2_RS18100 788deee00976c1e79f3f79c334dc5094 455 SUPERFAMILY SSF116726 370 448 2.62E-12 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS18100 788deee00976c1e79f3f79c334dc5094 455 SUPERFAMILY SSF51735 2 151 2.18E-31 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS18100 788deee00976c1e79f3f79c334dc5094 455 Gene3D G3DSA:3.30.70.1450 152 225 6.0E-6 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS18100 788deee00976c1e79f3f79c334dc5094 455 Gene3D G3DSA:3.30.70.1450 378 451 1.0E-6 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS08000 fa717c11ddc06f9561e4c355610ab303 124 SMART SM00450 23 118 8.6E-5 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS08000 fa717c11ddc06f9561e4c355610ab303 124 SUPERFAMILY SSF52821 22 105 1.51E-16 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS08000 fa717c11ddc06f9561e4c355610ab303 124 Gene3D G3DSA:3.40.250.10 24 105 7.2E-15 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS21405 3ab25cd2fbaa7f56c061a5a9c374d478 442 PANTHER PTHR22912 18 422 1.1E-79 T 22-04-2016 HRM2_RS21405 3ab25cd2fbaa7f56c061a5a9c374d478 442 Gene3D G3DSA:3.50.50.60 31 132 3.3E-19 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS21405 3ab25cd2fbaa7f56c061a5a9c374d478 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 175 200 9.9E-6 T 22-04-2016 HRM2_RS21405 3ab25cd2fbaa7f56c061a5a9c374d478 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 301 308 9.9E-6 T 22-04-2016 HRM2_RS21405 3ab25cd2fbaa7f56c061a5a9c374d478 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 33 55 9.9E-6 T 22-04-2016 HRM2_RS21405 3ab25cd2fbaa7f56c061a5a9c374d478 442 PANTHER PTHR22912:SF1 18 422 1.1E-79 T 22-04-2016 HRM2_RS21405 3ab25cd2fbaa7f56c061a5a9c374d478 442 SUPERFAMILY SSF51905 174 340 3.27E-23 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS21405 3ab25cd2fbaa7f56c061a5a9c374d478 442 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 33 331 6.3E-46 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS21405 3ab25cd2fbaa7f56c061a5a9c374d478 442 Gene3D G3DSA:3.50.50.60 133 340 7.3E-38 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS21405 3ab25cd2fbaa7f56c061a5a9c374d478 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 129 147 1.1E-10 T 22-04-2016 HRM2_RS21405 3ab25cd2fbaa7f56c061a5a9c374d478 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 286 308 1.1E-10 T 22-04-2016 HRM2_RS21405 3ab25cd2fbaa7f56c061a5a9c374d478 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 175 193 1.1E-10 T 22-04-2016 HRM2_RS21405 3ab25cd2fbaa7f56c061a5a9c374d478 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 277 1.1E-10 T 22-04-2016 HRM2_RS21405 3ab25cd2fbaa7f56c061a5a9c374d478 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 34 53 1.1E-10 T 22-04-2016 HRM2_RS21405 3ab25cd2fbaa7f56c061a5a9c374d478 442 SUPERFAMILY SSF51905 32 215 4.51E-35 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS06290 3fa67c5ebdeefedeb648d5a54b4cb2c8 359 PANTHER PTHR22926:SF5 2 359 1.0E-158 T 22-04-2016 HRM2_RS06290 3fa67c5ebdeefedeb648d5a54b4cb2c8 359 ProSitePatterns PS01348 MraY family signature 2. 187 198 - T 22-04-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HRM2_RS06290 3fa67c5ebdeefedeb648d5a54b4cb2c8 359 PANTHER PTHR22926 2 359 1.0E-158 T 22-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HRM2_RS06290 3fa67c5ebdeefedeb648d5a54b4cb2c8 359 Pfam PF00953 Glycosyl transferase family 4 99 282 2.4E-36 T 22-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HRM2_RS06290 3fa67c5ebdeefedeb648d5a54b4cb2c8 359 ProSitePatterns PS01347 MraY family signature 1. 68 80 - T 22-04-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HRM2_RS06290 3fa67c5ebdeefedeb648d5a54b4cb2c8 359 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 39 359 3.4E-124 T 22-04-2016 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HRM2_RS06290 3fa67c5ebdeefedeb648d5a54b4cb2c8 359 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 357 24.416 T 22-04-2016 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HRM2_RS06290 3fa67c5ebdeefedeb648d5a54b4cb2c8 359 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 68 80 9.1E-6 T 22-04-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HRM2_RS16900 f9bdb99123396d880ecd59df613d4db2 524 Gene3D G3DSA:3.30.450.40 11 177 8.0E-4 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS16900 f9bdb99123396d880ecd59df613d4db2 524 Gene3D G3DSA:3.40.50.300 191 367 6.9E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16900 f9bdb99123396d880ecd59df613d4db2 524 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 410 419 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS16900 f9bdb99123396d880ecd59df613d4db2 524 Gene3D G3DSA:1.10.10.60 464 507 2.0E-5 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS16900 f9bdb99123396d880ecd59df613d4db2 524 Gene3D G3DSA:1.10.8.60 368 444 1.7E-19 T 22-04-2016 HRM2_RS16900 f9bdb99123396d880ecd59df613d4db2 524 SMART SM00382 216 355 2.3E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS16900 f9bdb99123396d880ecd59df613d4db2 524 Pfam PF00158 Sigma-54 interaction domain 196 363 1.5E-65 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS16900 f9bdb99123396d880ecd59df613d4db2 524 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 220 233 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS16900 f9bdb99123396d880ecd59df613d4db2 524 SUPERFAMILY SSF52540 195 441 3.26E-63 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16900 f9bdb99123396d880ecd59df613d4db2 524 PANTHER PTHR32071 165 521 9.9E-137 T 22-04-2016 HRM2_RS23505 bf5fe5aceedfdeef0beadadc9cf79c74 707 Pfam PF00593 TonB dependent receptor 478 705 3.5E-9 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 HRM2_RS23505 bf5fe5aceedfdeef0beadadc9cf79c74 707 SUPERFAMILY SSF56935 42 409 1.26E-78 T 22-04-2016 HRM2_RS23505 bf5fe5aceedfdeef0beadadc9cf79c74 707 SUPERFAMILY SSF56935 439 707 1.26E-78 T 22-04-2016 HRM2_RS23505 bf5fe5aceedfdeef0beadadc9cf79c74 707 Gene3D G3DSA:2.40.170.20 165 707 1.6E-56 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 HRM2_RS23505 bf5fe5aceedfdeef0beadadc9cf79c74 707 Pfam PF07715 TonB-dependent Receptor Plug Domain 68 162 1.2E-13 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 HRM2_RS23505 bf5fe5aceedfdeef0beadadc9cf79c74 707 PANTHER PTHR32552 73 408 5.0E-18 T 22-04-2016 HRM2_RS23505 bf5fe5aceedfdeef0beadadc9cf79c74 707 PANTHER PTHR32552 442 707 5.0E-18 T 22-04-2016 HRM2_RS23505 bf5fe5aceedfdeef0beadadc9cf79c74 707 Gene3D G3DSA:2.170.130.10 36 164 7.7E-19 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 HRM2_RS08200 d96eb016084faaf8ecc1d206bc8fc27e 548 Gene3D G3DSA:2.30.38.10 365 439 9.3E-20 T 22-04-2016 HRM2_RS08200 d96eb016084faaf8ecc1d206bc8fc27e 548 PANTHER PTHR24096:SF136 5 544 3.8E-261 T 22-04-2016 HRM2_RS08200 d96eb016084faaf8ecc1d206bc8fc27e 548 Gene3D G3DSA:3.40.50.980 190 347 5.1E-34 T 22-04-2016 HRM2_RS08200 d96eb016084faaf8ecc1d206bc8fc27e 548 SUPERFAMILY SSF56801 15 547 1.01E-130 T 22-04-2016 HRM2_RS08200 d96eb016084faaf8ecc1d206bc8fc27e 548 Pfam PF13193 AMP-binding enzyme C-terminal domain 455 537 2.4E-15 T 22-04-2016 IPR025110 AMP-binding enzyme C-terminal domain HRM2_RS08200 d96eb016084faaf8ecc1d206bc8fc27e 548 Pfam PF00501 AMP-binding enzyme 28 446 6.9E-93 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS08200 d96eb016084faaf8ecc1d206bc8fc27e 548 Gene3D G3DSA:3.30.300.30 441 546 1.6E-22 T 22-04-2016 HRM2_RS08200 d96eb016084faaf8ecc1d206bc8fc27e 548 Gene3D G3DSA:3.40.50.980 19 189 1.6E-31 T 22-04-2016 HRM2_RS08200 d96eb016084faaf8ecc1d206bc8fc27e 548 PANTHER PTHR24096 5 544 3.8E-261 T 22-04-2016 HRM2_RS05260 5d29991baa0d23dd29161533fff18ec9 229 Gene3D G3DSA:3.40.50.300 8 50 2.9E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05260 5d29991baa0d23dd29161533fff18ec9 229 SUPERFAMILY SSF52540 7 194 7.19E-11 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04935 05bfd5fe4616b0ca00908943e0b54377 382 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 22-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 HRM2_RS04935 05bfd5fe4616b0ca00908943e0b54377 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 379 4.8E-49 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS04935 05bfd5fe4616b0ca00908943e0b54377 382 PANTHER PTHR10909 2 380 8.1E-158 T 22-04-2016 HRM2_RS04935 05bfd5fe4616b0ca00908943e0b54377 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 1.3E-37 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS04935 05bfd5fe4616b0ca00908943e0b54377 382 SUPERFAMILY SSF47203 231 380 1.93E-55 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS04935 05bfd5fe4616b0ca00908943e0b54377 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 220 6.6E-21 T 22-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 HRM2_RS04935 05bfd5fe4616b0ca00908943e0b54377 382 Gene3D G3DSA:1.20.140.10 220 380 2.6E-68 T 22-04-2016 HRM2_RS04935 05bfd5fe4616b0ca00908943e0b54377 382 Gene3D G3DSA:2.40.110.10 121 219 6.5E-37 T 22-04-2016 HRM2_RS04935 05bfd5fe4616b0ca00908943e0b54377 382 PIRSF PIRSF016578 4 364 8.1E-13 T 22-04-2016 HRM2_RS04935 05bfd5fe4616b0ca00908943e0b54377 382 PANTHER PTHR10909:SF305 2 380 8.1E-158 T 22-04-2016 HRM2_RS04935 05bfd5fe4616b0ca00908943e0b54377 382 SUPERFAMILY SSF56645 2 245 3.8E-85 T 22-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 HRM2_RS04935 05bfd5fe4616b0ca00908943e0b54377 382 Gene3D G3DSA:1.10.540.10 2 119 1.7E-45 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS04935 05bfd5fe4616b0ca00908943e0b54377 382 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 339 358 - T 22-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 HRM2_RS14095 c072f96fef623817903e101d6d4f8c14 298 SUPERFAMILY SSF161098 16 286 8.04E-32 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS14095 c072f96fef623817903e101d6d4f8c14 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 282 6.1E-13 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS14095 c072f96fef623817903e101d6d4f8c14 298 Gene3D G3DSA:1.10.3720.10 24 292 1.1E-33 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS14095 c072f96fef623817903e101d6d4f8c14 298 PANTHER PTHR30425 16 297 2.5E-55 T 22-04-2016 HRM2_RS13640 4beebd6bb5dd568b47fb146a66f690f4 307 PANTHER PTHR11405:SF1 1 302 1.6E-129 T 22-04-2016 HRM2_RS13640 4beebd6bb5dd568b47fb146a66f690f4 307 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 3 302 8.3E-118 T 22-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 HRM2_RS13640 4beebd6bb5dd568b47fb146a66f690f4 307 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 149 300 1.2E-53 T 22-04-2016 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 HRM2_RS13640 4beebd6bb5dd568b47fb146a66f690f4 307 SUPERFAMILY SSF53671 2 302 4.32E-102 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HRM2_RS13640 4beebd6bb5dd568b47fb146a66f690f4 307 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 143 6.5E-46 T 22-04-2016 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 HRM2_RS13640 4beebd6bb5dd568b47fb146a66f690f4 307 Gene3D G3DSA:3.40.50.1370 140 289 1.9E-60 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HRM2_RS13640 4beebd6bb5dd568b47fb146a66f690f4 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 255 264 8.0E-26 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HRM2_RS13640 4beebd6bb5dd568b47fb146a66f690f4 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 48 67 8.0E-26 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HRM2_RS13640 4beebd6bb5dd568b47fb146a66f690f4 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 267 290 8.0E-26 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HRM2_RS13640 4beebd6bb5dd568b47fb146a66f690f4 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 130 141 8.0E-26 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HRM2_RS13640 4beebd6bb5dd568b47fb146a66f690f4 307 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 48 55 - T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HRM2_RS13640 4beebd6bb5dd568b47fb146a66f690f4 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 79 92 1.9E-26 T 22-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 HRM2_RS13640 4beebd6bb5dd568b47fb146a66f690f4 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 219 229 1.9E-26 T 22-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 HRM2_RS13640 4beebd6bb5dd568b47fb146a66f690f4 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 46 60 1.9E-26 T 22-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 HRM2_RS13640 4beebd6bb5dd568b47fb146a66f690f4 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 119 133 1.9E-26 T 22-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 HRM2_RS13640 4beebd6bb5dd568b47fb146a66f690f4 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 281 292 1.9E-26 T 22-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 HRM2_RS13640 4beebd6bb5dd568b47fb146a66f690f4 307 Gene3D G3DSA:3.40.50.1370 2 139 3.6E-52 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HRM2_RS13640 4beebd6bb5dd568b47fb146a66f690f4 307 PANTHER PTHR11405 1 302 1.6E-129 T 22-04-2016 HRM2_RS13640 4beebd6bb5dd568b47fb146a66f690f4 307 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 2 303 73.477 T 22-04-2016 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 HRM2_RS24920 bb61099efa3c0bbfbfeabb6439f1c836 171 Pfam PF01966 HD domain 16 107 6.1E-9 T 22-04-2016 IPR006674 HD domain HRM2_RS24920 bb61099efa3c0bbfbfeabb6439f1c836 171 Gene3D G3DSA:1.10.3210.10 11 117 3.4E-13 T 22-04-2016 IPR006674 HD domain HRM2_RS24920 bb61099efa3c0bbfbfeabb6439f1c836 171 SUPERFAMILY SSF109604 15 108 2.59E-16 T 22-04-2016 HRM2_RS24920 bb61099efa3c0bbfbfeabb6439f1c836 171 TIGRFAM TIGR00277 HDIG: HDIG domain 13 84 5.0E-10 T 22-04-2016 IPR006675 HDIG domain HRM2_RS24920 bb61099efa3c0bbfbfeabb6439f1c836 171 SMART SM00471 10 118 9.5E-5 T 22-04-2016 IPR003607 HD/PDEase domain HRM2_RS17550 80eaf81cef819c5f1415a455be7ac40a 1200 Pfam PF01565 FAD binding domain 162 308 7.2E-23 T 22-04-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 HRM2_RS17550 80eaf81cef819c5f1415a455be7ac40a 1200 SUPERFAMILY SSF56176 125 384 2.0E-46 T 22-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 HRM2_RS17550 80eaf81cef819c5f1415a455be7ac40a 1200 SUPERFAMILY SSF46548 758 853 1.74E-13 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS17550 80eaf81cef819c5f1415a455be7ac40a 1200 Pfam PF13183 4Fe-4S dicluster domain 759 837 6.0E-12 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS17550 80eaf81cef819c5f1415a455be7ac40a 1200 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 761 772 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS17550 80eaf81cef819c5f1415a455be7ac40a 1200 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 823 834 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS17550 80eaf81cef819c5f1415a455be7ac40a 1200 SUPERFAMILY SSF55103 642 724 1.96E-31 T 22-04-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 HRM2_RS17550 80eaf81cef819c5f1415a455be7ac40a 1200 SUPERFAMILY SSF55103 419 550 1.96E-31 T 22-04-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 HRM2_RS17550 80eaf81cef819c5f1415a455be7ac40a 1200 Gene3D G3DSA:3.30.43.10 119 279 1.8E-33 T 22-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 HRM2_RS17550 80eaf81cef819c5f1415a455be7ac40a 1200 Pfam PF12447 Protein of unknown function (DUF3683) 4 110 4.7E-37 T 22-04-2016 IPR022153 Protein of unknown function DUF3683 HRM2_RS17550 80eaf81cef819c5f1415a455be7ac40a 1200 Pfam PF02913 FAD linked oxidases, C-terminal domain 616 722 6.0E-18 T 22-04-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 HRM2_RS17550 80eaf81cef819c5f1415a455be7ac40a 1200 Pfam PF02913 FAD linked oxidases, C-terminal domain 423 531 8.7E-7 T 22-04-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 HRM2_RS17550 80eaf81cef819c5f1415a455be7ac40a 1200 Pfam PF02754 Cysteine-rich domain 1076 1156 0.022 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS17550 80eaf81cef819c5f1415a455be7ac40a 1200 Pfam PF02754 Cysteine-rich domain 954 1043 2.1E-4 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS17550 80eaf81cef819c5f1415a455be7ac40a 1200 PANTHER PTHR11748 352 443 3.6E-45 T 22-04-2016 HRM2_RS17550 80eaf81cef819c5f1415a455be7ac40a 1200 PANTHER PTHR11748 520 770 3.6E-45 T 22-04-2016 HRM2_RS17550 80eaf81cef819c5f1415a455be7ac40a 1200 PANTHER PTHR11748 120 312 3.6E-45 T 22-04-2016 HRM2_RS17550 80eaf81cef819c5f1415a455be7ac40a 1200 Gene3D G3DSA:1.10.1060.10 757 855 7.9E-14 T 22-04-2016 HRM2_RS12815 5a49b1efa537bae6e50d199b351a38c2 222 Gene3D G3DSA:3.40.50.2300 2 135 2.6E-43 T 22-04-2016 HRM2_RS12815 5a49b1efa537bae6e50d199b351a38c2 222 PANTHER PTHR26402:SF495 6 152 4.8E-51 T 22-04-2016 HRM2_RS12815 5a49b1efa537bae6e50d199b351a38c2 222 SUPERFAMILY SSF52172 5 139 2.99E-42 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS12815 5a49b1efa537bae6e50d199b351a38c2 222 SMART SM00448 6 119 5.1E-40 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS12815 5a49b1efa537bae6e50d199b351a38c2 222 PANTHER PTHR26402 6 152 4.8E-51 T 22-04-2016 HRM2_RS12815 5a49b1efa537bae6e50d199b351a38c2 222 Pfam PF00072 Response regulator receiver domain 8 119 1.8E-30 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS12615 e4e2b57f84fe98312a685602bc1246a4 332 PANTHER PTHR11228 5 280 4.1E-34 T 22-04-2016 HRM2_RS12615 e4e2b57f84fe98312a685602bc1246a4 332 Pfam PF13186 Iron-sulfur cluster-binding domain 231 289 4.2E-10 T 22-04-2016 IPR023885 4Fe4S-binding SPASM domain HRM2_RS12615 e4e2b57f84fe98312a685602bc1246a4 332 Pfam PF13353 4Fe-4S single cluster domain 4 97 1.4E-6 T 22-04-2016 HRM2_RS12615 e4e2b57f84fe98312a685602bc1246a4 332 Gene3D G3DSA:3.20.20.70 4 290 6.8E-45 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS12615 e4e2b57f84fe98312a685602bc1246a4 332 PANTHER PTHR11228:SF7 5 280 4.1E-34 T 22-04-2016 HRM2_RS12615 e4e2b57f84fe98312a685602bc1246a4 332 Pfam PF04055 Radical SAM superfamily 6 157 1.5E-13 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS12615 e4e2b57f84fe98312a685602bc1246a4 332 SUPERFAMILY SSF102114 3 289 1.31E-45 T 22-04-2016 HRM2_RS18070 eb4f75bcfb02c850cbc2f07084793455 258 PANTHER PTHR17985:SF8 2 244 5.0E-81 T 22-04-2016 HRM2_RS18070 eb4f75bcfb02c850cbc2f07084793455 258 PANTHER PTHR17985 2 244 5.0E-81 T 22-04-2016 IPR008551 Transport and Golgi organisation protein 2 HRM2_RS18070 eb4f75bcfb02c850cbc2f07084793455 258 Pfam PF05742 Transport and Golgi organisation 2 1 239 4.7E-70 T 22-04-2016 IPR008551 Transport and Golgi organisation protein 2 HRM2_RS22545 b9e376e49b550cdc8b5ff69cdaf7ee26 310 Gene3D G3DSA:3.30.1330.60 186 304 6.4E-15 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS22545 b9e376e49b550cdc8b5ff69cdaf7ee26 310 Pfam PF00691 OmpA family 204 282 5.2E-10 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS22545 b9e376e49b550cdc8b5ff69cdaf7ee26 310 SUPERFAMILY SSF103088 194 304 2.88E-16 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS23115 0ed11d8a03d05a385e59982880273320 270 PANTHER PTHR12725:SF59 1 242 3.5E-63 T 22-04-2016 HRM2_RS23115 0ed11d8a03d05a385e59982880273320 270 SUPERFAMILY SSF56784 11 243 2.95E-27 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS23115 0ed11d8a03d05a385e59982880273320 270 Gene3D G3DSA:3.40.50.1000 103 243 1.5E-38 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS23115 0ed11d8a03d05a385e59982880273320 270 Pfam PF13419 Haloacid dehalogenase-like hydrolase 21 206 5.4E-9 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS23115 0ed11d8a03d05a385e59982880273320 270 PANTHER PTHR12725 1 242 3.5E-63 T 22-04-2016 HRM2_RS23115 0ed11d8a03d05a385e59982880273320 270 Gene3D G3DSA:1.10.150.240 32 102 4.3E-27 T 22-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 HRM2_RS08035 67093720cfab1240c84e2519fa6e5ea0 272 SMART SM00382 28 229 2.0E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS08035 67093720cfab1240c84e2519fa6e5ea0 272 Gene3D G3DSA:3.40.50.300 3 241 1.0E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08035 67093720cfab1240c84e2519fa6e5ea0 272 SUPERFAMILY SSF52540 3 238 3.24E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08035 67093720cfab1240c84e2519fa6e5ea0 272 PANTHER PTHR24220:SF582 5 251 1.3E-89 T 22-04-2016 HRM2_RS08035 67093720cfab1240c84e2519fa6e5ea0 272 PANTHER PTHR24220 5 251 1.3E-89 T 22-04-2016 HRM2_RS08035 67093720cfab1240c84e2519fa6e5ea0 272 Pfam PF00005 ABC transporter 20 168 3.5E-29 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS06625 42b5d7915c437c961b6899195ed6983c 261 PANTHER PTHR33445 1 163 9.9E-18 T 22-04-2016 HRM2_RS06625 42b5d7915c437c961b6899195ed6983c 261 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 197 10.173 T 22-04-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 HRM2_RS06625 42b5d7915c437c961b6899195ed6983c 261 Pfam PF00430 ATP synthase B/B' CF(0) 10 120 3.3E-17 T 22-04-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 HRM2_RS04270 b5318a72412020960a27fa011f3396c4 443 PIRSF PIRSF004539 1 443 6.0E-164 T 22-04-2016 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 HRM2_RS04270 b5318a72412020960a27fa011f3396c4 443 PANTHER PTHR36106 2 443 1.0E-227 T 22-04-2016 HRM2_RS04270 b5318a72412020960a27fa011f3396c4 443 PANTHER PTHR36106:SF3 2 443 1.0E-227 T 22-04-2016 HRM2_RS04270 b5318a72412020960a27fa011f3396c4 443 Pfam PF03605 Anaerobic c4-dicarboxylate membrane transporter 6 374 4.2E-141 T 22-04-2016 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 HRM2_RS04270 b5318a72412020960a27fa011f3396c4 443 TIGRFAM TIGR00770 Dcu: transporter, anaerobic C4-dicarboxylate uptake (Dcu) family 6 442 5.3E-147 T 22-04-2016 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 HRM2_RS11200 b829660eaa5139c9f19cae025af624e1 802 SUPERFAMILY SSF54211 626 801 6.83E-47 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS11200 b829660eaa5139c9f19cae025af624e1 802 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 707 715 - T 22-04-2016 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 HRM2_RS11200 b829660eaa5139c9f19cae025af624e1 802 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 40 233 3.5E-24 T 22-04-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 HRM2_RS11200 b829660eaa5139c9f19cae025af624e1 802 TIGRFAM TIGR00763 lon: endopeptidase La 42 802 7.7E-287 T 22-04-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 HRM2_RS11200 b829660eaa5139c9f19cae025af624e1 802 PIRSF PIRSF001174 15 802 4.0E-284 T 22-04-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 HRM2_RS11200 b829660eaa5139c9f19cae025af624e1 802 SMART SM00382 380 528 6.0E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS11200 b829660eaa5139c9f19cae025af624e1 802 Gene3D G3DSA:3.40.50.300 340 531 2.6E-31 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11200 b829660eaa5139c9f19cae025af624e1 802 SMART SM00464 39 233 6.7E-28 T 22-04-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 HRM2_RS11200 b829660eaa5139c9f19cae025af624e1 802 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 602 801 1.3E-76 T 22-04-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 HRM2_RS11200 b829660eaa5139c9f19cae025af624e1 802 Gene3D G3DSA:3.30.230.10 625 802 4.9E-65 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HRM2_RS11200 b829660eaa5139c9f19cae025af624e1 802 Hamap MF_01973 Lon protease [lon]. 40 800 59.066 T 22-04-2016 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 HRM2_RS11200 b829660eaa5139c9f19cae025af624e1 802 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 384 521 2.3E-23 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HRM2_RS11200 b829660eaa5139c9f19cae025af624e1 802 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 757 775 2.7E-49 T 22-04-2016 HRM2_RS11200 b829660eaa5139c9f19cae025af624e1 802 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 734 753 2.7E-49 T 22-04-2016 HRM2_RS11200 b829660eaa5139c9f19cae025af624e1 802 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 704 723 2.7E-49 T 22-04-2016 HRM2_RS11200 b829660eaa5139c9f19cae025af624e1 802 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 388 407 2.7E-49 T 22-04-2016 HRM2_RS11200 b829660eaa5139c9f19cae025af624e1 802 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 625 641 2.7E-49 T 22-04-2016 HRM2_RS11200 b829660eaa5139c9f19cae025af624e1 802 Gene3D G3DSA:1.10.8.60 532 616 2.4E-28 T 22-04-2016 HRM2_RS11200 b829660eaa5139c9f19cae025af624e1 802 SUPERFAMILY SSF88697 41 232 1.66E-18 T 22-04-2016 IPR015947 PUA-like domain HRM2_RS11200 b829660eaa5139c9f19cae025af624e1 802 PANTHER PTHR10046 13 802 0.0 T 22-04-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 HRM2_RS11200 b829660eaa5139c9f19cae025af624e1 802 SUPERFAMILY SSF52540 341 620 3.17E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07980 a9e0def20679c78cec17b00839861955 600 Gene3D G3DSA:1.10.540.10 37 157 3.1E-12 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS07980 a9e0def20679c78cec17b00839861955 600 PANTHER PTHR10909:SF296 9 475 2.8E-140 T 22-04-2016 HRM2_RS07980 a9e0def20679c78cec17b00839861955 600 Gene3D G3DSA:2.40.110.10 160 264 1.3E-20 T 22-04-2016 HRM2_RS07980 a9e0def20679c78cec17b00839861955 600 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 283 450 4.8E-18 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS07980 a9e0def20679c78cec17b00839861955 600 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 33 9.1E-10 T 22-04-2016 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria HRM2_RS07980 a9e0def20679c78cec17b00839861955 600 SUPERFAMILY SSF56645 38 269 1.44E-45 T 22-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 HRM2_RS07980 a9e0def20679c78cec17b00839861955 600 Gene3D G3DSA:1.20.140.10 265 460 1.2E-44 T 22-04-2016 HRM2_RS07980 a9e0def20679c78cec17b00839861955 600 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 41 156 1.6E-8 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS07980 a9e0def20679c78cec17b00839861955 600 PANTHER PTHR10909 9 475 2.8E-140 T 22-04-2016 HRM2_RS07980 a9e0def20679c78cec17b00839861955 600 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 161 268 3.8E-14 T 22-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 HRM2_RS07980 a9e0def20679c78cec17b00839861955 600 SUPERFAMILY SSF47203 289 471 5.96E-42 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS07980 a9e0def20679c78cec17b00839861955 600 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 466 590 7.9E-32 T 22-04-2016 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain HRM2_RS04900 d490c21625167759ed48b85a91d1a224 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 257 1.1E-54 T 22-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 HRM2_RS04900 d490c21625167759ed48b85a91d1a224 259 SUPERFAMILY SSF52096 3 257 6.4E-74 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS04900 d490c21625167759ed48b85a91d1a224 259 PANTHER PTHR11941 5 256 5.6E-85 T 22-04-2016 HRM2_RS04900 d490c21625167759ed48b85a91d1a224 259 Gene3D G3DSA:3.90.226.10 2 257 1.2E-72 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS03250 91a38ede3bbfb16c0cb315b862c3ca67 519 Gene3D G3DSA:2.40.50.140 30 155 1.9E-31 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS03250 91a38ede3bbfb16c0cb315b862c3ca67 519 PANTHER PTHR30001 1 515 4.2E-197 T 22-04-2016 HRM2_RS03250 91a38ede3bbfb16c0cb315b862c3ca67 519 SUPERFAMILY SSF50249 39 80 7.57E-16 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS03250 91a38ede3bbfb16c0cb315b862c3ca67 519 SUPERFAMILY SSF50249 111 155 7.57E-16 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS03250 91a38ede3bbfb16c0cb315b862c3ca67 519 Pfam PF10150 Ribonuclease E/G family 151 420 2.3E-104 T 22-04-2016 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 HRM2_RS03250 91a38ede3bbfb16c0cb315b862c3ca67 519 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 453 4.0E-154 T 22-04-2016 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 HRM2_RS03710 410fa8e0e091abeab4ae48e45b2ddc8a 377 Gene3D G3DSA:1.10.3660.10 253 375 2.7E-44 T 22-04-2016 HRM2_RS03710 410fa8e0e091abeab4ae48e45b2ddc8a 377 SMART SM00830 13 93 3.7E-22 T 22-04-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 HRM2_RS03710 410fa8e0e091abeab4ae48e45b2ddc8a 377 Pfam PF02153 Prephenate dehydrogenase 143 344 2.3E-29 T 22-04-2016 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 HRM2_RS03710 410fa8e0e091abeab4ae48e45b2ddc8a 377 PANTHER PTHR21363:SF0 92 376 1.3E-54 T 22-04-2016 HRM2_RS03710 410fa8e0e091abeab4ae48e45b2ddc8a 377 PANTHER PTHR21363 92 376 1.3E-54 T 22-04-2016 HRM2_RS03710 410fa8e0e091abeab4ae48e45b2ddc8a 377 Gene3D G3DSA:3.40.50.720 91 252 2.0E-40 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS03710 410fa8e0e091abeab4ae48e45b2ddc8a 377 Gene3D G3DSA:1.20.59.10 5 90 3.2E-19 T 22-04-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 HRM2_RS03710 410fa8e0e091abeab4ae48e45b2ddc8a 377 Pfam PF01817 Chorismate mutase type II 13 90 3.8E-19 T 22-04-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 HRM2_RS03710 410fa8e0e091abeab4ae48e45b2ddc8a 377 SUPERFAMILY SSF51735 103 242 2.72E-36 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS03710 410fa8e0e091abeab4ae48e45b2ddc8a 377 SUPERFAMILY SSF48600 4 91 1.15E-21 T 22-04-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 HRM2_RS03710 410fa8e0e091abeab4ae48e45b2ddc8a 377 SUPERFAMILY SSF48179 246 372 3.4E-38 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HRM2_RS24090 d885014f2746d2302f77fb72e7dc467a 283 Pfam PF01012 Electron transfer flavoprotein domain 25 192 1.3E-36 T 22-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 HRM2_RS24090 d885014f2746d2302f77fb72e7dc467a 283 PANTHER PTHR21294 2 268 1.8E-69 T 22-04-2016 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 HRM2_RS24090 d885014f2746d2302f77fb72e7dc467a 283 SMART SM00893 23 220 6.9E-34 T 22-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 HRM2_RS24090 d885014f2746d2302f77fb72e7dc467a 283 PANTHER PTHR21294:SF0 2 268 1.8E-69 T 22-04-2016 HRM2_RS24090 d885014f2746d2302f77fb72e7dc467a 283 Gene3D G3DSA:3.40.50.620 2 260 1.6E-69 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS24090 d885014f2746d2302f77fb72e7dc467a 283 SUPERFAMILY SSF52402 2 260 1.73E-55 T 22-04-2016 HRM2_RS24090 d885014f2746d2302f77fb72e7dc467a 283 PIRSF PIRSF000090 2 265 1.0E-60 T 22-04-2016 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 HRM2_RS00375 ce40a0111749b3eef8dea7e2d2b7dc06 492 SMART SM00065 9 156 0.0023 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS00375 ce40a0111749b3eef8dea7e2d2b7dc06 492 Gene3D G3DSA:3.30.450.40 6 158 3.2E-14 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS00375 ce40a0111749b3eef8dea7e2d2b7dc06 492 SUPERFAMILY SSF55781 11 156 1.72E-15 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS00375 ce40a0111749b3eef8dea7e2d2b7dc06 492 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 393 402 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS00375 ce40a0111749b3eef8dea7e2d2b7dc06 492 Gene3D G3DSA:1.10.8.60 353 422 6.4E-22 T 22-04-2016 HRM2_RS00375 ce40a0111749b3eef8dea7e2d2b7dc06 492 Gene3D G3DSA:1.10.10.60 447 491 5.5E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS00375 ce40a0111749b3eef8dea7e2d2b7dc06 492 Gene3D G3DSA:3.40.50.300 178 352 1.9E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00375 ce40a0111749b3eef8dea7e2d2b7dc06 492 SUPERFAMILY SSF52540 179 421 4.11E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00375 ce40a0111749b3eef8dea7e2d2b7dc06 492 Pfam PF13185 GAF domain 10 147 7.4E-9 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS00375 ce40a0111749b3eef8dea7e2d2b7dc06 492 PANTHER PTHR32071 153 491 2.4E-139 T 22-04-2016 HRM2_RS00375 ce40a0111749b3eef8dea7e2d2b7dc06 492 SMART SM00382 200 344 2.8E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS00375 ce40a0111749b3eef8dea7e2d2b7dc06 492 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 266 281 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS00375 ce40a0111749b3eef8dea7e2d2b7dc06 492 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 204 217 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS00375 ce40a0111749b3eef8dea7e2d2b7dc06 492 SUPERFAMILY SSF46689 393 491 2.06E-5 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS00375 ce40a0111749b3eef8dea7e2d2b7dc06 492 Pfam PF00158 Sigma-54 interaction domain 180 346 3.0E-67 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS13205 0410fad658a188bb65d16d76340eca26 749 Gene3D G3DSA:1.10.1780.10 1 140 1.1E-32 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 HRM2_RS13205 0410fad658a188bb65d16d76340eca26 749 SMART SM01086 656 745 1.8E-30 T 22-04-2016 IPR019489 Clp ATPase, C-terminal HRM2_RS13205 0410fad658a188bb65d16d76340eca26 749 Gene3D G3DSA:3.40.50.300 442 663 2.0E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13205 0410fad658a188bb65d16d76340eca26 749 SUPERFAMILY SSF52540 173 423 1.23E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13205 0410fad658a188bb65d16d76340eca26 749 Pfam PF07724 AAA domain (Cdc48 subfamily) 487 649 4.5E-47 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HRM2_RS13205 0410fad658a188bb65d16d76340eca26 749 SUPERFAMILY SSF52540 438 733 1.02E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13205 0410fad658a188bb65d16d76340eca26 749 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 519 537 - T 22-04-2016 IPR028299 ClpA/B, conserved site 2 HRM2_RS13205 0410fad658a188bb65d16d76340eca26 749 SUPERFAMILY SSF81923 1 140 2.49E-45 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 HRM2_RS13205 0410fad658a188bb65d16d76340eca26 749 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 213 316 1.3E-11 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HRM2_RS13205 0410fad658a188bb65d16d76340eca26 749 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 13 60 1.3E-7 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 HRM2_RS13205 0410fad658a188bb65d16d76340eca26 749 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 656 735 3.9E-23 T 22-04-2016 IPR019489 Clp ATPase, C-terminal HRM2_RS13205 0410fad658a188bb65d16d76340eca26 749 SMART SM00382 488 624 5.7E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS13205 0410fad658a188bb65d16d76340eca26 749 SMART SM00382 208 354 1.2E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS13205 0410fad658a188bb65d16d76340eca26 749 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 492 510 2.0E-37 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 HRM2_RS13205 0410fad658a188bb65d16d76340eca26 749 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 596 610 2.0E-37 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 HRM2_RS13205 0410fad658a188bb65d16d76340eca26 749 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 563 581 2.0E-37 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 HRM2_RS13205 0410fad658a188bb65d16d76340eca26 749 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 534 552 2.0E-37 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 HRM2_RS13205 0410fad658a188bb65d16d76340eca26 749 Gene3D G3DSA:3.40.50.300 175 352 1.2E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13205 0410fad658a188bb65d16d76340eca26 749 Gene3D G3DSA:1.10.8.60 664 748 7.5E-29 T 22-04-2016 HRM2_RS13205 0410fad658a188bb65d16d76340eca26 749 PANTHER PTHR11638:SF111 1 749 0.0 T 22-04-2016 HRM2_RS13205 0410fad658a188bb65d16d76340eca26 749 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 2 736 0.0 T 22-04-2016 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0004176 HRM2_RS13205 0410fad658a188bb65d16d76340eca26 749 PANTHER PTHR11638 1 749 0.0 T 22-04-2016 HRM2_RS13205 0410fad658a188bb65d16d76340eca26 749 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 304 316 - T 22-04-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 HRM2_RS13205 0410fad658a188bb65d16d76340eca26 749 Gene3D G3DSA:1.10.8.60 353 433 2.0E-27 T 22-04-2016 HRM2_RS17415 747aa3d4d1b3a53c0c5aae9421c5bf38 348 Gene3D G3DSA:3.30.420.40 166 192 1.7E-34 T 22-04-2016 HRM2_RS17415 747aa3d4d1b3a53c0c5aae9421c5bf38 348 Gene3D G3DSA:3.30.420.40 270 324 1.7E-34 T 22-04-2016 HRM2_RS17415 747aa3d4d1b3a53c0c5aae9421c5bf38 348 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 12 342 2.0E-158 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 HRM2_RS17415 747aa3d4d1b3a53c0c5aae9421c5bf38 348 Pfam PF06723 MreB/Mbl protein 14 342 8.3E-148 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 HRM2_RS17415 747aa3d4d1b3a53c0c5aae9421c5bf38 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 54 72 2.0E-62 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 HRM2_RS17415 747aa3d4d1b3a53c0c5aae9421c5bf38 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 193 213 2.0E-62 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 HRM2_RS17415 747aa3d4d1b3a53c0c5aae9421c5bf38 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 74 97 2.0E-62 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 HRM2_RS17415 747aa3d4d1b3a53c0c5aae9421c5bf38 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 138 157 2.0E-62 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 HRM2_RS17415 747aa3d4d1b3a53c0c5aae9421c5bf38 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 307 333 2.0E-62 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 HRM2_RS17415 747aa3d4d1b3a53c0c5aae9421c5bf38 348 PANTHER PTHR19375:SF117 12 333 1.6E-171 T 22-04-2016 HRM2_RS17415 747aa3d4d1b3a53c0c5aae9421c5bf38 348 Gene3D G3DSA:3.30.420.40 13 165 1.2E-46 T 22-04-2016 HRM2_RS17415 747aa3d4d1b3a53c0c5aae9421c5bf38 348 SUPERFAMILY SSF53067 155 340 4.21E-48 T 22-04-2016 HRM2_RS17415 747aa3d4d1b3a53c0c5aae9421c5bf38 348 SUPERFAMILY SSF53067 12 154 7.2E-40 T 22-04-2016 HRM2_RS17415 747aa3d4d1b3a53c0c5aae9421c5bf38 348 Gene3D G3DSA:3.90.640.10 193 265 2.3E-28 T 22-04-2016 HRM2_RS17415 747aa3d4d1b3a53c0c5aae9421c5bf38 348 PANTHER PTHR19375 12 333 1.6E-171 T 22-04-2016 HRM2_RS11060 6dad908ee5903b5fe166b88f37cc23cd 205 SUPERFAMILY SSF69593 15 149 1.44E-17 T 22-04-2016 HRM2_RS11060 6dad908ee5903b5fe166b88f37cc23cd 205 PANTHER PTHR10434 17 173 1.1E-44 T 22-04-2016 HRM2_RS11060 6dad908ee5903b5fe166b88f37cc23cd 205 PANTHER PTHR10434:SF9 17 173 1.1E-44 T 22-04-2016 HRM2_RS11060 6dad908ee5903b5fe166b88f37cc23cd 205 Gene3D G3DSA:3.40.1130.10 40 129 2.7E-5 T 22-04-2016 HRM2_RS11060 6dad908ee5903b5fe166b88f37cc23cd 205 SMART SM00563 44 153 2.4E-16 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 HRM2_RS11060 6dad908ee5903b5fe166b88f37cc23cd 205 Pfam PF01553 Acyltransferase 41 149 9.3E-10 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 HRM2_RS01785 a71be42acc6daa40d2aff5454242e2d9 523 PANTHER PTHR13285:SF24 1 65 3.0E-134 T 22-04-2016 HRM2_RS01785 a71be42acc6daa40d2aff5454242e2d9 523 PANTHER PTHR13285:SF24 93 382 3.0E-134 T 22-04-2016 HRM2_RS01785 a71be42acc6daa40d2aff5454242e2d9 523 PANTHER PTHR13285:SF24 399 488 3.0E-134 T 22-04-2016 HRM2_RS01785 a71be42acc6daa40d2aff5454242e2d9 523 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 175 377 5.5E-24 T 22-04-2016 IPR004299 Membrane bound O-acyl transferase, MBOAT HRM2_RS01785 a71be42acc6daa40d2aff5454242e2d9 523 PIRSF PIRSF500217 81 523 2.2E-130 T 22-04-2016 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 KEGG: 00061+2.3.1.-|KEGG: 00253+2.3.1.-|KEGG: 00261+2.3.1.-|KEGG: 00310+2.3.1.-|KEGG: 00330+2.3.1.-|KEGG: 00332+2.3.1.-|KEGG: 00340+2.3.1.-|KEGG: 00350+2.3.1.-|KEGG: 00564+2.3.1.-|KEGG: 00565+2.3.1.-|KEGG: 00604+2.3.1.-|KEGG: 00623+2.3.1.-|KEGG: 00626+2.3.1.-|KEGG: 00627+2.3.1.-|KEGG: 00642+2.3.1.-|KEGG: 00650+2.3.1.-|KEGG: 00680+2.3.1.-|KEGG: 00903+2.3.1.-|KEGG: 00904+2.3.1.-|KEGG: 00906+2.3.1.-|KEGG: 00940+2.3.1.-|KEGG: 00942+2.3.1.-|KEGG: 00950+2.3.1.-|KEGG: 00960+2.3.1.-|KEGG: 00965+2.3.1.-|UniPathway: UPA00286 HRM2_RS01785 a71be42acc6daa40d2aff5454242e2d9 523 PIRSF PIRSF016636 81 523 2.9E-129 T 22-04-2016 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB HRM2_RS01785 a71be42acc6daa40d2aff5454242e2d9 523 PANTHER PTHR13285 1 65 3.0E-134 T 22-04-2016 HRM2_RS01785 a71be42acc6daa40d2aff5454242e2d9 523 PANTHER PTHR13285 93 382 3.0E-134 T 22-04-2016 HRM2_RS01785 a71be42acc6daa40d2aff5454242e2d9 523 PANTHER PTHR13285 399 488 3.0E-134 T 22-04-2016 HRM2_RS23880 d5e1165db9ac1a41463e97ca398faa55 134 Pfam PF00085 Thioredoxin 35 121 6.7E-14 T 22-04-2016 IPR013766 Thioredoxin domain GO:0045454 HRM2_RS23880 d5e1165db9ac1a41463e97ca398faa55 134 SUPERFAMILY SSF52833 21 122 5.08E-25 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS23880 d5e1165db9ac1a41463e97ca398faa55 134 Gene3D G3DSA:3.40.30.10 30 121 2.0E-23 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS23880 d5e1165db9ac1a41463e97ca398faa55 134 PANTHER PTHR10438 37 122 3.4E-16 T 22-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 HRM2_RS23880 d5e1165db9ac1a41463e97ca398faa55 134 PANTHER PTHR10438:SF215 37 122 3.4E-16 T 22-04-2016 HRM2_RS20980 ace7d606d1ee2fe1e68a8dabddc059cf 1157 Pfam PF00580 UvrD/REP helicase N-terminal domain 498 592 3.7E-25 T 22-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 HRM2_RS20980 ace7d606d1ee2fe1e68a8dabddc059cf 1157 Pfam PF00580 UvrD/REP helicase N-terminal domain 627 757 2.8E-29 T 22-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 HRM2_RS20980 ace7d606d1ee2fe1e68a8dabddc059cf 1157 Gene3D G3DSA:3.40.50.300 767 896 4.0E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20980 ace7d606d1ee2fe1e68a8dabddc059cf 1157 Gene3D G3DSA:3.40.50.300 1045 1132 4.0E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20980 ace7d606d1ee2fe1e68a8dabddc059cf 1157 Gene3D G3DSA:3.40.50.300 496 761 3.0E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20980 ace7d606d1ee2fe1e68a8dabddc059cf 1157 Pfam PF13361 UvrD-like helicase C-terminal domain 1021 1109 1.1E-24 T 22-04-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 HRM2_RS20980 ace7d606d1ee2fe1e68a8dabddc059cf 1157 Pfam PF13361 UvrD-like helicase C-terminal domain 763 937 1.0E-15 T 22-04-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 HRM2_RS20980 ace7d606d1ee2fe1e68a8dabddc059cf 1157 SUPERFAMILY SSF52540 493 1132 5.08E-125 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20980 ace7d606d1ee2fe1e68a8dabddc059cf 1157 PANTHER PTHR11070:SF7 1022 1140 1.7E-132 T 22-04-2016 HRM2_RS20980 ace7d606d1ee2fe1e68a8dabddc059cf 1157 PANTHER PTHR11070:SF7 491 828 1.7E-132 T 22-04-2016 HRM2_RS20980 ace7d606d1ee2fe1e68a8dabddc059cf 1157 PANTHER PTHR11070:SF7 846 1002 1.7E-132 T 22-04-2016 HRM2_RS20980 ace7d606d1ee2fe1e68a8dabddc059cf 1157 SUPERFAMILY SSF89550 2 252 5.49E-11 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 HRM2_RS20980 ace7d606d1ee2fe1e68a8dabddc059cf 1157 PANTHER PTHR11070 1022 1140 1.7E-132 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 HRM2_RS20980 ace7d606d1ee2fe1e68a8dabddc059cf 1157 PANTHER PTHR11070 491 828 1.7E-132 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 HRM2_RS20980 ace7d606d1ee2fe1e68a8dabddc059cf 1157 PANTHER PTHR11070 846 1002 1.7E-132 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 HRM2_RS18530 82e8f7dca833f99fe6b3ce4c1eb44f76 182 PANTHER PTHR32154:SF17 1 182 9.8E-38 T 22-04-2016 HRM2_RS18530 82e8f7dca833f99fe6b3ce4c1eb44f76 182 PANTHER PTHR32154 1 182 9.8E-38 T 22-04-2016 HRM2_RS18530 82e8f7dca833f99fe6b3ce4c1eb44f76 182 SUPERFAMILY SSF53323 4 176 1.57E-35 T 22-04-2016 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 HRM2_RS18530 82e8f7dca833f99fe6b3ce4c1eb44f76 182 Gene3D G3DSA:3.40.920.10 2 175 3.2E-39 T 22-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HRM2_RS18530 82e8f7dca833f99fe6b3ce4c1eb44f76 182 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 173 4.8E-29 T 22-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HRM2_RS14985 5f77f21f76069ce54d0aa65eee41bcf1 68 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 61 15.039 T 22-04-2016 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HRM2_RS14985 5f77f21f76069ce54d0aa65eee41bcf1 68 Pfam PF01192 RNA polymerase Rpb6 8 58 2.0E-12 T 22-04-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HRM2_RS14985 5f77f21f76069ce54d0aa65eee41bcf1 68 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 2 58 1.6E-16 T 22-04-2016 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HRM2_RS14985 5f77f21f76069ce54d0aa65eee41bcf1 68 Gene3D G3DSA:3.90.940.10 2 66 1.9E-11 T 22-04-2016 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HRM2_RS14985 5f77f21f76069ce54d0aa65eee41bcf1 68 PANTHER PTHR34476 2 58 5.1E-13 T 22-04-2016 HRM2_RS14985 5f77f21f76069ce54d0aa65eee41bcf1 68 SMART SM01409 8 60 1.9E-13 T 22-04-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HRM2_RS14985 5f77f21f76069ce54d0aa65eee41bcf1 68 SUPERFAMILY SSF63562 2 63 3.4E-17 T 22-04-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HRM2_RS02385 49d1bb29bf06a9ad2d2dc5c99cb30731 387 Pfam PF01168 Alanine racemase, N-terminal domain 15 244 3.8E-71 T 22-04-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HRM2_RS02385 49d1bb29bf06a9ad2d2dc5c99cb30731 387 PRINTS PR00992 Alanine racemase signature 34 50 1.9E-61 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HRM2_RS02385 49d1bb29bf06a9ad2d2dc5c99cb30731 387 PRINTS PR00992 Alanine racemase signature 312 329 1.9E-61 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HRM2_RS02385 49d1bb29bf06a9ad2d2dc5c99cb30731 387 PRINTS PR00992 Alanine racemase signature 70 88 1.9E-61 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HRM2_RS02385 49d1bb29bf06a9ad2d2dc5c99cb30731 387 PRINTS PR00992 Alanine racemase signature 217 244 1.9E-61 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HRM2_RS02385 49d1bb29bf06a9ad2d2dc5c99cb30731 387 PRINTS PR00992 Alanine racemase signature 274 289 1.9E-61 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HRM2_RS02385 49d1bb29bf06a9ad2d2dc5c99cb30731 387 PRINTS PR00992 Alanine racemase signature 131 143 1.9E-61 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HRM2_RS02385 49d1bb29bf06a9ad2d2dc5c99cb30731 387 PRINTS PR00992 Alanine racemase signature 291 306 1.9E-61 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HRM2_RS02385 49d1bb29bf06a9ad2d2dc5c99cb30731 387 PRINTS PR00992 Alanine racemase signature 368 381 1.9E-61 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HRM2_RS02385 49d1bb29bf06a9ad2d2dc5c99cb30731 387 Hamap MF_01201 Alanine racemase. 8 386 34.837 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HRM2_RS02385 49d1bb29bf06a9ad2d2dc5c99cb30731 387 PANTHER PTHR30511 5 387 7.5E-151 T 22-04-2016 HRM2_RS02385 49d1bb29bf06a9ad2d2dc5c99cb30731 387 SUPERFAMILY SSF51419 15 259 1.22E-71 T 22-04-2016 IPR029066 PLP-binding barrel HRM2_RS02385 49d1bb29bf06a9ad2d2dc5c99cb30731 387 TIGRFAM TIGR00492 alr: alanine racemase 11 385 1.1E-118 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HRM2_RS02385 49d1bb29bf06a9ad2d2dc5c99cb30731 387 SMART SM01005 258 386 7.0E-62 T 22-04-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HRM2_RS02385 49d1bb29bf06a9ad2d2dc5c99cb30731 387 SUPERFAMILY SSF50621 252 386 1.4E-46 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 HRM2_RS02385 49d1bb29bf06a9ad2d2dc5c99cb30731 387 Gene3D G3DSA:3.20.20.10 17 233 4.0E-77 T 22-04-2016 IPR029066 PLP-binding barrel HRM2_RS02385 49d1bb29bf06a9ad2d2dc5c99cb30731 387 Pfam PF00842 Alanine racemase, C-terminal domain 258 385 4.5E-39 T 22-04-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HRM2_RS02385 49d1bb29bf06a9ad2d2dc5c99cb30731 387 Gene3D G3DSA:2.40.37.10 234 386 1.8E-58 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 HRM2_RS02385 49d1bb29bf06a9ad2d2dc5c99cb30731 387 PANTHER PTHR30511:SF0 5 387 7.5E-151 T 22-04-2016 HRM2_RS02385 49d1bb29bf06a9ad2d2dc5c99cb30731 387 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 39 49 - T 22-04-2016 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HRM2_RS16315 04c077accbf77f318cfe58f103cd2688 416 Pfam PF01808 AICARFT/IMPCHase bienzyme 46 314 2.4E-63 T 22-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 HRM2_RS16315 04c077accbf77f318cfe58f103cd2688 416 SUPERFAMILY SSF53927 48 416 3.01E-100 T 22-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 HRM2_RS16315 04c077accbf77f318cfe58f103cd2688 416 SMART SM00798 9 315 3.1E-42 T 22-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 HRM2_RS16315 04c077accbf77f318cfe58f103cd2688 416 PANTHER PTHR11692:SF2 50 416 7.5E-100 T 22-04-2016 HRM2_RS16315 04c077accbf77f318cfe58f103cd2688 416 Gene3D G3DSA:3.40.140.20 93 209 4.1E-40 T 22-04-2016 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 HRM2_RS16315 04c077accbf77f318cfe58f103cd2688 416 PANTHER PTHR11692 50 416 7.5E-100 T 22-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 HRM2_RS16315 04c077accbf77f318cfe58f103cd2688 416 Gene3D G3DSA:3.40.140.20 252 406 8.4E-43 T 22-04-2016 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 HRM2_RS08220 0055b4b3bd11398b6a4eb94ac3989ffa 548 Gene3D G3DSA:3.30.70.20 13 56 6.3E-15 T 22-04-2016 HRM2_RS08220 0055b4b3bd11398b6a4eb94ac3989ffa 548 SUPERFAMILY SSF75138 439 544 1.07E-13 T 22-04-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like HRM2_RS08220 0055b4b3bd11398b6a4eb94ac3989ffa 548 SUPERFAMILY SSF54862 10 66 1.74E-18 T 22-04-2016 HRM2_RS08220 0055b4b3bd11398b6a4eb94ac3989ffa 548 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 18 29 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS08220 0055b4b3bd11398b6a4eb94ac3989ffa 548 Pfam PF00037 4Fe-4S binding domain 12 34 6.2E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS08220 0055b4b3bd11398b6a4eb94ac3989ffa 548 Gene3D G3DSA:3.40.1390.20 437 543 3.9E-11 T 22-04-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like HRM2_RS08220 0055b4b3bd11398b6a4eb94ac3989ffa 548 Pfam PF04060 Putative Fe-S cluster 392 423 6.0E-11 T 22-04-2016 IPR007202 4Fe-4S domain GO:0051536 HRM2_RS08220 0055b4b3bd11398b6a4eb94ac3989ffa 548 SUPERFAMILY SSF53920 46 369 3.53E-32 T 22-04-2016 IPR009016 Iron hydrogenase HRM2_RS08220 0055b4b3bd11398b6a4eb94ac3989ffa 548 Gene3D G3DSA:3.40.50.1780 57 101 5.3E-6 T 22-04-2016 HRM2_RS08220 0055b4b3bd11398b6a4eb94ac3989ffa 548 Gene3D G3DSA:3.40.50.1780 145 267 5.3E-6 T 22-04-2016 HRM2_RS08220 0055b4b3bd11398b6a4eb94ac3989ffa 548 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 92 316 2.0E-14 T 22-04-2016 IPR004108 Iron hydrogenase, large subunit, C-terminal HRM2_RS05025 e381080e4f359b00666b620ef82f28e5 387 Gene3D G3DSA:3.20.20.10 35 258 7.7E-61 T 22-04-2016 IPR029066 PLP-binding barrel HRM2_RS05025 e381080e4f359b00666b620ef82f28e5 387 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 74 86 8.8E-16 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 HRM2_RS05025 e381080e4f359b00666b620ef82f28e5 387 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 261 280 8.8E-16 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 HRM2_RS05025 e381080e4f359b00666b620ef82f28e5 387 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 54 72 8.8E-16 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 HRM2_RS05025 e381080e4f359b00666b620ef82f28e5 387 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 177 190 8.8E-16 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 HRM2_RS05025 e381080e4f359b00666b620ef82f28e5 387 PANTHER PTHR11482 3 387 6.3E-120 T 22-04-2016 HRM2_RS05025 e381080e4f359b00666b620ef82f28e5 387 Gene3D G3DSA:2.40.37.10 259 387 7.1E-27 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 HRM2_RS05025 e381080e4f359b00666b620ef82f28e5 387 PANTHER PTHR11482:SF6 3 387 6.3E-120 T 22-04-2016 HRM2_RS05025 e381080e4f359b00666b620ef82f28e5 387 PRINTS PR01182 Ornithine decarboxylase signature 96 120 2.1E-16 T 22-04-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 HRM2_RS05025 e381080e4f359b00666b620ef82f28e5 387 PRINTS PR01182 Ornithine decarboxylase signature 26 50 2.1E-16 T 22-04-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 HRM2_RS05025 e381080e4f359b00666b620ef82f28e5 387 PRINTS PR01182 Ornithine decarboxylase signature 126 148 2.1E-16 T 22-04-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 HRM2_RS05025 e381080e4f359b00666b620ef82f28e5 387 PRINTS PR01182 Ornithine decarboxylase signature 329 339 2.1E-16 T 22-04-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 HRM2_RS05025 e381080e4f359b00666b620ef82f28e5 387 PRINTS PR01182 Ornithine decarboxylase signature 52 79 2.1E-16 T 22-04-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 HRM2_RS05025 e381080e4f359b00666b620ef82f28e5 387 SUPERFAMILY SSF50621 246 387 1.76E-31 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 HRM2_RS05025 e381080e4f359b00666b620ef82f28e5 387 SUPERFAMILY SSF51419 25 273 1.72E-62 T 22-04-2016 IPR029066 PLP-binding barrel HRM2_RS05025 e381080e4f359b00666b620ef82f28e5 387 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 40 271 1.3E-51 T 22-04-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Reactome: REACT_13 HRM2_RS05025 e381080e4f359b00666b620ef82f28e5 387 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 277 385 2.0E-15 T 22-04-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 HRM2_RS21190 083d8b54ad71da9fa8ba1564cd0ea680 733 PANTHER PTHR22931:SF7 637 725 1.6E-89 T 22-04-2016 HRM2_RS21190 083d8b54ad71da9fa8ba1564cd0ea680 733 PANTHER PTHR22931:SF7 1 379 1.6E-89 T 22-04-2016 HRM2_RS21190 083d8b54ad71da9fa8ba1564cd0ea680 733 PANTHER PTHR22931 637 725 1.6E-89 T 22-04-2016 HRM2_RS21190 083d8b54ad71da9fa8ba1564cd0ea680 733 PANTHER PTHR22931 1 379 1.6E-89 T 22-04-2016 HRM2_RS21190 083d8b54ad71da9fa8ba1564cd0ea680 733 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 17 314 3.8E-66 T 22-04-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 HRM2_RS21190 083d8b54ad71da9fa8ba1564cd0ea680 733 SUPERFAMILY SSF52009 626 728 3.14E-26 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS21190 083d8b54ad71da9fa8ba1564cd0ea680 733 Gene3D G3DSA:3.30.470.20 186 313 1.4E-25 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS21190 083d8b54ad71da9fa8ba1564cd0ea680 733 SUPERFAMILY SSF56059 3 313 1.29E-63 T 22-04-2016 HRM2_RS21190 083d8b54ad71da9fa8ba1564cd0ea680 733 Gene3D G3DSA:3.30.1490.20 2 185 6.1E-42 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HRM2_RS21190 083d8b54ad71da9fa8ba1564cd0ea680 733 Gene3D G3DSA:3.50.30.10 627 725 5.3E-23 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS21190 083d8b54ad71da9fa8ba1564cd0ea680 733 Pfam PF00391 PEP-utilising enzyme, mobile domain 652 723 1.5E-18 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS18315 ec65e681c070765b561cfdb6d0e87167 696 PIRSF PIRSF005419 6 696 2.1E-259 T 22-04-2016 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HRM2_RS18315 ec65e681c070765b561cfdb6d0e87167 696 Pfam PF00771 FHIPEP family 28 685 3.2E-272 T 22-04-2016 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HRM2_RS18315 ec65e681c070765b561cfdb6d0e87167 696 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 144 167 - T 22-04-2016 IPR025505 FHIPEP conserved site HRM2_RS18315 ec65e681c070765b561cfdb6d0e87167 696 PANTHER PTHR30161 1 696 0.0 T 22-04-2016 HRM2_RS18315 ec65e681c070765b561cfdb6d0e87167 696 PANTHER PTHR30161:SF1 1 696 0.0 T 22-04-2016 HRM2_RS18315 ec65e681c070765b561cfdb6d0e87167 696 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 35 48 1.1E-53 T 22-04-2016 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HRM2_RS18315 ec65e681c070765b561cfdb6d0e87167 696 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 188 205 1.1E-53 T 22-04-2016 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HRM2_RS18315 ec65e681c070765b561cfdb6d0e87167 696 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 139 155 1.1E-53 T 22-04-2016 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HRM2_RS18315 ec65e681c070765b561cfdb6d0e87167 696 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 158 176 1.1E-53 T 22-04-2016 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HRM2_RS18315 ec65e681c070765b561cfdb6d0e87167 696 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 239 253 1.1E-53 T 22-04-2016 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HRM2_RS18315 ec65e681c070765b561cfdb6d0e87167 696 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 72 91 1.1E-53 T 22-04-2016 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HRM2_RS18315 ec65e681c070765b561cfdb6d0e87167 696 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 17 693 1.4E-271 T 22-04-2016 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 HRM2_RS04350 38d4722fcefa6cbda150ff10aac975b3 603 Gene3D G3DSA:2.40.110.10 160 271 2.5E-25 T 22-04-2016 HRM2_RS04350 38d4722fcefa6cbda150ff10aac975b3 603 PANTHER PTHR10909:SF296 9 478 4.0E-161 T 22-04-2016 HRM2_RS04350 38d4722fcefa6cbda150ff10aac975b3 603 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 163 175 - T 22-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 HRM2_RS04350 38d4722fcefa6cbda150ff10aac975b3 603 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 39 156 5.9E-11 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS04350 38d4722fcefa6cbda150ff10aac975b3 603 SUPERFAMILY SSF47203 282 467 1.5E-41 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS04350 38d4722fcefa6cbda150ff10aac975b3 603 Gene3D G3DSA:1.20.140.10 275 463 9.2E-48 T 22-04-2016 HRM2_RS04350 38d4722fcefa6cbda150ff10aac975b3 603 PANTHER PTHR10909 9 478 4.0E-161 T 22-04-2016 HRM2_RS04350 38d4722fcefa6cbda150ff10aac975b3 603 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 469 597 6.9E-29 T 22-04-2016 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain HRM2_RS04350 38d4722fcefa6cbda150ff10aac975b3 603 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 284 453 3.4E-21 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS04350 38d4722fcefa6cbda150ff10aac975b3 603 SUPERFAMILY SSF56645 37 270 1.57E-50 T 22-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 HRM2_RS04350 38d4722fcefa6cbda150ff10aac975b3 603 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 5 34 5.5E-9 T 22-04-2016 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria HRM2_RS04350 38d4722fcefa6cbda150ff10aac975b3 603 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 269 9.5E-18 T 22-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 HRM2_RS04350 38d4722fcefa6cbda150ff10aac975b3 603 Gene3D G3DSA:1.10.540.10 37 158 8.9E-15 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS05355 54989e98cb3c808e8d8d274ade36c636 120 PANTHER PTHR33823 1 116 7.9E-38 T 22-04-2016 HRM2_RS05355 54989e98cb3c808e8d8d274ade36c636 120 SUPERFAMILY SSF57716 80 116 3.99E-9 T 22-04-2016 HRM2_RS05355 54989e98cb3c808e8d8d274ade36c636 120 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 78 112 8.4E-12 T 22-04-2016 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 HRM2_RS05355 54989e98cb3c808e8d8d274ade36c636 120 PANTHER PTHR33823:SF2 1 116 7.9E-38 T 22-04-2016 HRM2_RS05355 54989e98cb3c808e8d8d274ade36c636 120 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 83 107 - T 22-04-2016 IPR020458 Zinc finger, DksA/TraR C4-type conserved site HRM2_RS05355 54989e98cb3c808e8d8d274ade36c636 120 SUPERFAMILY SSF109635 1 79 4.84E-23 T 22-04-2016 HRM2_RS05355 54989e98cb3c808e8d8d274ade36c636 120 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 1 110 1.3E-41 T 22-04-2016 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 HRM2_RS15440 02042aa046340afe90ee3c77682e996c 370 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 91 - T 22-04-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 HRM2_RS15440 02042aa046340afe90ee3c77682e996c 370 SUPERFAMILY SSF53597 151 366 6.87E-61 T 22-04-2016 IPR024072 Dihydrofolate reductase-like domain HRM2_RS15440 02042aa046340afe90ee3c77682e996c 370 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 150 365 1.8E-57 T 22-04-2016 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 HRM2_RS15440 02042aa046340afe90ee3c77682e996c 370 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 102 6.2E-20 T 22-04-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 HRM2_RS15440 02042aa046340afe90ee3c77682e996c 370 Gene3D G3DSA:3.40.140.10 3 132 6.0E-33 T 22-04-2016 HRM2_RS15440 02042aa046340afe90ee3c77682e996c 370 PANTHER PTHR11079 1 225 1.2E-56 T 22-04-2016 HRM2_RS15440 02042aa046340afe90ee3c77682e996c 370 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 10 362 6.2E-107 T 22-04-2016 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525|UniPathway: UPA00275|UniPathway: UPA00275 HRM2_RS15440 02042aa046340afe90ee3c77682e996c 370 Pfam PF01872 RibD C-terminal domain 151 362 8.5E-47 T 22-04-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 HRM2_RS15440 02042aa046340afe90ee3c77682e996c 370 PIRSF PIRSF006769 1 370 3.5E-128 T 22-04-2016 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525|UniPathway: UPA00275|UniPathway: UPA00275 HRM2_RS15440 02042aa046340afe90ee3c77682e996c 370 PANTHER PTHR11079:SF10 1 225 1.2E-56 T 22-04-2016 HRM2_RS15440 02042aa046340afe90ee3c77682e996c 370 Gene3D G3DSA:3.40.430.10 133 368 5.8E-73 T 22-04-2016 IPR024072 Dihydrofolate reductase-like domain HRM2_RS15440 02042aa046340afe90ee3c77682e996c 370 SUPERFAMILY SSF53927 6 147 2.58E-44 T 22-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 HRM2_RS12120 3ae727af1b7d7612648ceeb692c283a2 145 PANTHER PTHR33164 4 144 4.0E-24 T 22-04-2016 HRM2_RS12120 3ae727af1b7d7612648ceeb692c283a2 145 Gene3D G3DSA:1.10.10.10 8 143 2.7E-31 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS12120 3ae727af1b7d7612648ceeb692c283a2 145 SMART SM00347 30 130 4.7E-13 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS12120 3ae727af1b7d7612648ceeb692c283a2 145 Pfam PF12802 MarR family 35 94 3.8E-11 T 22-04-2016 HRM2_RS12120 3ae727af1b7d7612648ceeb692c283a2 145 SUPERFAMILY SSF46785 7 144 9.5E-29 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS13645 0cb5842dfcbc8b4eae43bb291d2c874d 391 Gene3D G3DSA:3.90.1150.10 301 390 2.6E-41 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS13645 0cb5842dfcbc8b4eae43bb291d2c874d 391 Gene3D G3DSA:3.90.1150.10 4 54 2.6E-41 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS13645 0cb5842dfcbc8b4eae43bb291d2c874d 391 PANTHER PTHR11986 2 391 5.3E-185 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HRM2_RS13645 0cb5842dfcbc8b4eae43bb291d2c874d 391 SUPERFAMILY SSF53383 8 390 4.35E-129 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS13645 0cb5842dfcbc8b4eae43bb291d2c874d 391 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 8 391 46.154 T 22-04-2016 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 HRM2_RS13645 0cb5842dfcbc8b4eae43bb291d2c874d 391 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 10 390 7.9E-156 T 22-04-2016 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 HRM2_RS13645 0cb5842dfcbc8b4eae43bb291d2c874d 391 PANTHER PTHR11986:SF79 2 391 5.3E-185 T 22-04-2016 HRM2_RS13645 0cb5842dfcbc8b4eae43bb291d2c874d 391 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 217 254 - T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HRM2_RS13645 0cb5842dfcbc8b4eae43bb291d2c874d 391 Gene3D G3DSA:3.40.640.10 55 298 8.2E-91 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS13645 0cb5842dfcbc8b4eae43bb291d2c874d 391 Pfam PF00202 Aminotransferase class-III 16 389 5.7E-122 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HRM2_RS22165 5ff14cd838b057f3a1b1e61782acfc3e 757 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 681 693 1.9E-20 T 22-04-2016 HRM2_RS22165 5ff14cd838b057f3a1b1e61782acfc3e 757 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 473 492 1.9E-20 T 22-04-2016 HRM2_RS22165 5ff14cd838b057f3a1b1e61782acfc3e 757 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 645 660 1.9E-20 T 22-04-2016 HRM2_RS22165 5ff14cd838b057f3a1b1e61782acfc3e 757 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 628 643 1.9E-20 T 22-04-2016 HRM2_RS22165 5ff14cd838b057f3a1b1e61782acfc3e 757 SMART SM00065 27 174 3.2E-10 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS22165 5ff14cd838b057f3a1b1e61782acfc3e 757 PANTHER PTHR22931:SF28 231 731 1.8E-125 T 22-04-2016 HRM2_RS22165 5ff14cd838b057f3a1b1e61782acfc3e 757 Pfam PF13185 GAF domain 26 165 1.4E-12 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS22165 5ff14cd838b057f3a1b1e61782acfc3e 757 Gene3D G3DSA:3.30.450.40 14 177 2.5E-36 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS22165 5ff14cd838b057f3a1b1e61782acfc3e 757 Gene3D G3DSA:3.50.30.10 317 432 3.4E-24 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS22165 5ff14cd838b057f3a1b1e61782acfc3e 757 Pfam PF05524 PEP-utilising enzyme, N-terminal 190 311 3.0E-14 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 HRM2_RS22165 5ff14cd838b057f3a1b1e61782acfc3e 757 Pfam PF00391 PEP-utilising enzyme, mobile domain 336 408 9.8E-14 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS22165 5ff14cd838b057f3a1b1e61782acfc3e 757 SUPERFAMILY SSF51621 428 723 3.43E-89 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HRM2_RS22165 5ff14cd838b057f3a1b1e61782acfc3e 757 Gene3D G3DSA:1.10.274.10 227 316 7.2E-18 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 HRM2_RS22165 5ff14cd838b057f3a1b1e61782acfc3e 757 PANTHER PTHR22931 231 731 1.8E-125 T 22-04-2016 HRM2_RS22165 5ff14cd838b057f3a1b1e61782acfc3e 757 Gene3D G3DSA:3.20.20.60 437 747 3.3E-90 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HRM2_RS22165 5ff14cd838b057f3a1b1e61782acfc3e 757 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 189 742 4.9E-124 T 22-04-2016 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 HRM2_RS22165 5ff14cd838b057f3a1b1e61782acfc3e 757 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 436 719 5.0E-90 T 22-04-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 HRM2_RS22165 5ff14cd838b057f3a1b1e61782acfc3e 757 SUPERFAMILY SSF52009 310 428 7.72E-22 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS22165 5ff14cd838b057f3a1b1e61782acfc3e 757 SUPERFAMILY SSF55781 14 170 2.14E-28 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS22165 5ff14cd838b057f3a1b1e61782acfc3e 757 SUPERFAMILY SSF47831 224 325 1.28E-17 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 HRM2_RS04625 1b3d11ad3b143eb2fc82445147e174c6 236 Gene3D G3DSA:1.10.3290.10 157 224 4.3E-10 T 22-04-2016 IPR003812 Fido domain HRM2_RS09365 4219cac427fce9fd454524695638cb06 1067 Pfam PF13109 AsmA-like C-terminal region 867 1034 1.9E-14 T 22-04-2016 HRM2_RS02780 c66e13b801917451239c8f51fb77efce 573 PANTHER PTHR22935 257 470 3.2E-29 T 22-04-2016 HRM2_RS02780 c66e13b801917451239c8f51fb77efce 573 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 144 412 1.8E-50 T 22-04-2016 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 HRM2_RS02780 c66e13b801917451239c8f51fb77efce 573 PANTHER PTHR22935:SF68 257 470 3.2E-29 T 22-04-2016 HRM2_RS11160 54231f5b8bb48401e991831f879a66db 372 SUPERFAMILY SSF103263 4 369 6.67E-129 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS11160 54231f5b8bb48401e991831f879a66db 372 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 22-04-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS11160 54231f5b8bb48401e991831f879a66db 372 PANTHER PTHR21085 2 269 3.6E-167 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS11160 54231f5b8bb48401e991831f879a66db 372 PANTHER PTHR21085 286 368 3.6E-167 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS11160 54231f5b8bb48401e991831f879a66db 372 Hamap MF_00300 Chorismate synthase [aroC]. 10 370 35.094 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS11160 54231f5b8bb48401e991831f879a66db 372 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 22-04-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS11160 54231f5b8bb48401e991831f879a66db 372 TIGRFAM TIGR00033 aroC: chorismate synthase 10 369 1.8E-119 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS11160 54231f5b8bb48401e991831f879a66db 372 Pfam PF01264 Chorismate synthase 10 366 6.4E-134 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS11160 54231f5b8bb48401e991831f879a66db 372 Gene3D G3DSA:3.60.150.10 10 369 2.8E-141 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS11160 54231f5b8bb48401e991831f879a66db 372 PIRSF PIRSF001456 3 372 6.6E-133 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS24945 8993fb17de79e803105e78255d404500 539 SUPERFAMILY SSF46548 441 519 9.59E-18 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS24945 8993fb17de79e803105e78255d404500 539 Pfam PF13534 4Fe-4S dicluster domain 313 386 4.1E-7 T 22-04-2016 HRM2_RS24945 8993fb17de79e803105e78255d404500 539 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 495 506 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS24945 8993fb17de79e803105e78255d404500 539 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 447 458 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS24945 8993fb17de79e803105e78255d404500 539 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 371 382 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS24945 8993fb17de79e803105e78255d404500 539 Pfam PF13183 4Fe-4S dicluster domain 444 509 9.4E-10 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS24945 8993fb17de79e803105e78255d404500 539 SUPERFAMILY SSF103501 3 30 8.76E-10 T 22-04-2016 IPR023234 NarG-like domain HRM2_RS24945 8993fb17de79e803105e78255d404500 539 SUPERFAMILY SSF103501 57 166 8.76E-10 T 22-04-2016 IPR023234 NarG-like domain HRM2_RS24945 8993fb17de79e803105e78255d404500 539 Gene3D G3DSA:1.20.950.20 3 197 9.1E-31 T 22-04-2016 HRM2_RS24945 8993fb17de79e803105e78255d404500 539 Gene3D G3DSA:1.20.950.20 253 289 9.1E-31 T 22-04-2016 HRM2_RS24945 8993fb17de79e803105e78255d404500 539 SUPERFAMILY SSF46548 295 391 9.94E-12 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS24945 8993fb17de79e803105e78255d404500 539 Gene3D G3DSA:1.10.1060.10 309 383 1.4E-12 T 22-04-2016 HRM2_RS24945 8993fb17de79e803105e78255d404500 539 Gene3D G3DSA:1.10.1060.10 453 522 1.3E-15 T 22-04-2016 HRM2_RS24945 8993fb17de79e803105e78255d404500 539 Gene3D G3DSA:3.30.70.20 384 452 4.7E-5 T 22-04-2016 HRM2_RS24945 8993fb17de79e803105e78255d404500 539 SUPERFAMILY SSF103501 255 289 8.37E-8 T 22-04-2016 IPR023234 NarG-like domain HRM2_RS15685 62926e7dd40b16c5254b7c3bd07835a1 511 SUPERFAMILY SSF53649 8 78 7.2E-66 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 HRM2_RS15685 62926e7dd40b16c5254b7c3bd07835a1 511 SUPERFAMILY SSF53649 308 510 7.2E-66 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 HRM2_RS15685 62926e7dd40b16c5254b7c3bd07835a1 511 PIRSF PIRSF001492 1 511 2.2E-199 T 22-04-2016 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 HRM2_RS15685 62926e7dd40b16c5254b7c3bd07835a1 511 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 8 511 1.6E-203 T 22-04-2016 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 HRM2_RS15685 62926e7dd40b16c5254b7c3bd07835a1 511 PANTHER PTHR31637:SF0 8 511 6.4E-249 T 22-04-2016 HRM2_RS15685 62926e7dd40b16c5254b7c3bd07835a1 511 Gene3D G3DSA:3.40.1450.10 79 309 3.3E-92 T 22-04-2016 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 HRM2_RS15685 62926e7dd40b16c5254b7c3bd07835a1 511 SUPERFAMILY SSF64158 78 309 1.2E-83 T 22-04-2016 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 HRM2_RS15685 62926e7dd40b16c5254b7c3bd07835a1 511 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 5 511 46.064 T 22-04-2016 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 HRM2_RS15685 62926e7dd40b16c5254b7c3bd07835a1 511 Gene3D G3DSA:3.40.720.10 314 510 2.1E-78 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 HRM2_RS15685 62926e7dd40b16c5254b7c3bd07835a1 511 Gene3D G3DSA:3.40.720.10 8 78 2.1E-78 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 HRM2_RS15685 62926e7dd40b16c5254b7c3bd07835a1 511 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 83 299 1.7E-79 T 22-04-2016 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 HRM2_RS15685 62926e7dd40b16c5254b7c3bd07835a1 511 Pfam PF01676 Metalloenzyme superfamily 7 500 4.3E-73 T 22-04-2016 IPR006124 Metalloenzyme GO:0003824|GO:0046872 HRM2_RS15685 62926e7dd40b16c5254b7c3bd07835a1 511 PANTHER PTHR31637 8 511 6.4E-249 T 22-04-2016 HRM2_RS10510 aa03458b1fae62b3d0db5b75577e0f36 320 SUPERFAMILY SSF56112 47 311 1.46E-29 T 22-04-2016 IPR011009 Protein kinase-like domain HRM2_RS10510 aa03458b1fae62b3d0db5b75577e0f36 320 Gene3D G3DSA:3.90.1200.10 141 265 4.2E-17 T 22-04-2016 HRM2_RS10510 aa03458b1fae62b3d0db5b75577e0f36 320 Pfam PF01636 Phosphotransferase enzyme family 50 266 1.3E-17 T 22-04-2016 IPR002575 Aminoglycoside phosphotransferase HRM2_RS20425 36da4a51f58c9eaef13ae7fadec96fb8 155 Pfam PF02743 Cache domain 8 115 5.9E-13 T 22-04-2016 IPR033479 Double Cache domain 1 HRM2_RS20425 36da4a51f58c9eaef13ae7fadec96fb8 155 Gene3D G3DSA:3.30.450.20 8 131 2.4E-21 T 22-04-2016 HRM2_RS01270 d61abfb9b3b8f42761432d80574dfa54 381 Pfam PF00072 Response regulator receiver domain 264 371 3.1E-20 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS01270 d61abfb9b3b8f42761432d80574dfa54 381 Gene3D G3DSA:3.30.565.10 79 241 2.8E-33 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS01270 d61abfb9b3b8f42761432d80574dfa54 381 Gene3D G3DSA:3.40.50.2300 262 379 2.7E-30 T 22-04-2016 HRM2_RS01270 d61abfb9b3b8f42761432d80574dfa54 381 SUPERFAMILY SSF55874 79 243 8.77E-32 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS01270 d61abfb9b3b8f42761432d80574dfa54 381 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 120 241 9.0E-17 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS01270 d61abfb9b3b8f42761432d80574dfa54 381 PRINTS PR00344 Bacterial sensor protein C-terminal signature 170 184 2.6E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS01270 d61abfb9b3b8f42761432d80574dfa54 381 PRINTS PR00344 Bacterial sensor protein C-terminal signature 203 221 2.6E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS01270 d61abfb9b3b8f42761432d80574dfa54 381 PRINTS PR00344 Bacterial sensor protein C-terminal signature 188 198 2.6E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS01270 d61abfb9b3b8f42761432d80574dfa54 381 PRINTS PR00344 Bacterial sensor protein C-terminal signature 227 240 2.6E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS01270 d61abfb9b3b8f42761432d80574dfa54 381 SMART SM00448 262 374 2.0E-20 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS01270 d61abfb9b3b8f42761432d80574dfa54 381 PANTHER PTHR24423:SF544 16 380 1.6E-90 T 22-04-2016 HRM2_RS01270 d61abfb9b3b8f42761432d80574dfa54 381 SUPERFAMILY SSF47384 14 76 3.92E-5 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS01270 d61abfb9b3b8f42761432d80574dfa54 381 SUPERFAMILY SSF52172 263 379 1.99E-29 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS01270 d61abfb9b3b8f42761432d80574dfa54 381 PANTHER PTHR24423 16 380 1.6E-90 T 22-04-2016 HRM2_RS01270 d61abfb9b3b8f42761432d80574dfa54 381 SMART SM00387 119 243 2.7E-27 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS02680 be59debbc182dd017af41b19546c8e29 390 PANTHER PTHR30085:SF1 8 170 6.7E-140 T 22-04-2016 HRM2_RS02680 be59debbc182dd017af41b19546c8e29 390 PANTHER PTHR30085:SF1 249 390 6.7E-140 T 22-04-2016 HRM2_RS02680 be59debbc182dd017af41b19546c8e29 390 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 81 143 1.6E-14 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HRM2_RS02680 be59debbc182dd017af41b19546c8e29 390 SUPERFAMILY SSF161098 183 371 1.24E-30 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS02680 be59debbc182dd017af41b19546c8e29 390 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 385 5.3E-14 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS02680 be59debbc182dd017af41b19546c8e29 390 SUPERFAMILY SSF161098 82 150 4.71E-12 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS02680 be59debbc182dd017af41b19546c8e29 390 Gene3D G3DSA:1.10.3720.10 183 385 1.3E-36 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS02680 be59debbc182dd017af41b19546c8e29 390 Gene3D G3DSA:1.10.3720.10 82 150 2.9E-13 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS02680 be59debbc182dd017af41b19546c8e29 390 PANTHER PTHR30085 8 170 6.7E-140 T 22-04-2016 HRM2_RS02680 be59debbc182dd017af41b19546c8e29 390 PANTHER PTHR30085 249 390 6.7E-140 T 22-04-2016 HRM2_RS14195 1e9800ba4b1c81805fed3155e8cdb99c 677 SUPERFAMILY SSF56801 37 667 4.06E-141 T 22-04-2016 HRM2_RS14195 1e9800ba4b1c81805fed3155e8cdb99c 677 ProSitePatterns PS00455 Putative AMP-binding domain signature. 282 293 - T 22-04-2016 IPR020845 AMP-binding, conserved site HRM2_RS14195 1e9800ba4b1c81805fed3155e8cdb99c 677 Gene3D G3DSA:2.30.38.10 458 547 3.6E-5 T 22-04-2016 HRM2_RS14195 1e9800ba4b1c81805fed3155e8cdb99c 677 PANTHER PTHR24095 20 674 1.7E-212 T 22-04-2016 HRM2_RS14195 1e9800ba4b1c81805fed3155e8cdb99c 677 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 49 671 2.5E-232 T 22-04-2016 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: REACT_13433 HRM2_RS14195 1e9800ba4b1c81805fed3155e8cdb99c 677 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 46 93 2.2E-13 T 22-04-2016 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 HRM2_RS14195 1e9800ba4b1c81805fed3155e8cdb99c 677 Pfam PF00501 AMP-binding enzyme 95 553 6.6E-79 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS14195 1e9800ba4b1c81805fed3155e8cdb99c 677 Gene3D G3DSA:3.30.300.30 549 666 4.1E-23 T 22-04-2016 HRM2_RS14195 1e9800ba4b1c81805fed3155e8cdb99c 677 Gene3D G3DSA:3.40.50.980 91 218 1.0E-33 T 22-04-2016 HRM2_RS14195 1e9800ba4b1c81805fed3155e8cdb99c 677 Gene3D G3DSA:3.40.50.980 256 287 1.0E-33 T 22-04-2016 HRM2_RS14195 1e9800ba4b1c81805fed3155e8cdb99c 677 Gene3D G3DSA:3.40.50.980 288 444 1.7E-22 T 22-04-2016 HRM2_RS14195 1e9800ba4b1c81805fed3155e8cdb99c 677 Pfam PF13193 AMP-binding enzyme C-terminal domain 562 640 2.4E-17 T 22-04-2016 IPR025110 AMP-binding enzyme C-terminal domain HRM2_RS09375 abe4bd38842546285cc4eb4541184303 691 Gene3D G3DSA:3.90.226.10 343 559 5.8E-60 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS09375 abe4bd38842546285cc4eb4541184303 691 Pfam PF03572 Peptidase family S41 368 540 5.1E-48 T 22-04-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 HRM2_RS09375 abe4bd38842546285cc4eb4541184303 691 PANTHER PTHR32060:SF11 1 615 3.5E-202 T 22-04-2016 HRM2_RS09375 abe4bd38842546285cc4eb4541184303 691 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 209 562 4.8E-87 T 22-04-2016 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 HRM2_RS09375 abe4bd38842546285cc4eb4541184303 691 SMART SM00228 250 328 6.6E-5 T 22-04-2016 IPR001478 PDZ domain GO:0005515 HRM2_RS09375 abe4bd38842546285cc4eb4541184303 691 SMART SM00245 333 542 1.3E-51 T 22-04-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 HRM2_RS09375 abe4bd38842546285cc4eb4541184303 691 PANTHER PTHR32060 1 615 3.5E-202 T 22-04-2016 HRM2_RS09375 abe4bd38842546285cc4eb4541184303 691 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 243 324 2.4E-9 T 22-04-2016 IPR001478 PDZ domain GO:0005515 HRM2_RS09375 abe4bd38842546285cc4eb4541184303 691 Pfam PF11818 C-terminal domain of tail specific protease (DUF3340) 545 681 1.4E-29 T 22-04-2016 IPR020992 Tail specific protease, C-terminal HRM2_RS09375 abe4bd38842546285cc4eb4541184303 691 Gene3D G3DSA:2.30.42.10 250 342 1.2E-15 T 22-04-2016 IPR001478 PDZ domain GO:0005515 HRM2_RS09375 abe4bd38842546285cc4eb4541184303 691 SUPERFAMILY SSF50156 241 326 1.37E-9 T 22-04-2016 IPR001478 PDZ domain GO:0005515 HRM2_RS09375 abe4bd38842546285cc4eb4541184303 691 SUPERFAMILY SSF52096 358 546 1.57E-65 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS09375 abe4bd38842546285cc4eb4541184303 691 SUPERFAMILY SSF52096 198 268 1.57E-65 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS08340 8f5204a99a59c700036a922c92d400d9 301 Pfam PF00288 GHMP kinases N terminal domain 93 150 1.7E-6 T 22-04-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 HRM2_RS08340 8f5204a99a59c700036a922c92d400d9 301 SUPERFAMILY SSF55060 169 281 3.74E-20 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain HRM2_RS08340 8f5204a99a59c700036a922c92d400d9 301 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 7 291 1.9E-62 T 22-04-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560|UniPathway: UPA00056 HRM2_RS08340 8f5204a99a59c700036a922c92d400d9 301 SUPERFAMILY SSF54211 4 161 1.21E-36 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS08340 8f5204a99a59c700036a922c92d400d9 301 PANTHER PTHR20861:SF2 6 294 3.7E-70 T 22-04-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560|UniPathway: UPA00056 HRM2_RS08340 8f5204a99a59c700036a922c92d400d9 301 Gene3D G3DSA:3.30.70.890 169 280 2.0E-20 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain HRM2_RS08340 8f5204a99a59c700036a922c92d400d9 301 Hamap MF_00061 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 3 291 29.871 T 22-04-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560|UniPathway: UPA00056 HRM2_RS08340 8f5204a99a59c700036a922c92d400d9 301 Gene3D G3DSA:3.30.230.10 5 161 1.4E-43 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HRM2_RS08340 8f5204a99a59c700036a922c92d400d9 301 PANTHER PTHR20861 6 294 3.7E-70 T 22-04-2016 HRM2_RS08340 8f5204a99a59c700036a922c92d400d9 301 PIRSF PIRSF010376 3 296 1.8E-74 T 22-04-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560|UniPathway: UPA00056 HRM2_RS23305 a153b8b85c60c424c6aa4e6b42ea4b77 309 Pfam PF04216 Protein involved in formate dehydrogenase formation 12 305 1.1E-27 T 22-04-2016 IPR006452 Formate dehydrogenase accessory protein GO:0005737 HRM2_RS23305 a153b8b85c60c424c6aa4e6b42ea4b77 309 Gene3D G3DSA:3.90.1670.10 5 308 6.5E-67 T 22-04-2016 IPR024064 FdhE-like HRM2_RS23305 a153b8b85c60c424c6aa4e6b42ea4b77 309 PANTHER PTHR37689:SF1 188 309 1.6E-22 T 22-04-2016 HRM2_RS23305 a153b8b85c60c424c6aa4e6b42ea4b77 309 PANTHER PTHR37689 188 309 1.6E-22 T 22-04-2016 HRM2_RS23305 a153b8b85c60c424c6aa4e6b42ea4b77 309 SUPERFAMILY SSF144020 12 308 6.02E-47 T 22-04-2016 IPR024064 FdhE-like HRM2_RS23640 1715a9fb91ffcc22f01c99d0f735e03b 376 SUPERFAMILY SSF56235 140 353 2.83E-23 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal HRM2_RS23640 1715a9fb91ffcc22f01c99d0f735e03b 376 Gene3D G3DSA:3.60.20.10 146 350 3.8E-25 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal HRM2_RS23640 1715a9fb91ffcc22f01c99d0f735e03b 376 Gene3D G3DSA:3.60.20.10 2 40 3.8E-25 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal HRM2_RS18795 e1400316ab9e1cb8dfd06672dbb941ef 399 SUPERFAMILY SSF54631 273 392 1.18E-17 T 22-04-2016 HRM2_RS18795 e1400316ab9e1cb8dfd06672dbb941ef 399 Gene3D G3DSA:3.40.50.300 37 264 9.5E-79 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18795 e1400316ab9e1cb8dfd06672dbb941ef 399 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS18795 e1400316ab9e1cb8dfd06672dbb941ef 399 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 36 393 9.8E-144 T 22-04-2016 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 HRM2_RS18795 e1400316ab9e1cb8dfd06672dbb941ef 399 Pfam PF00005 ABC transporter 44 191 2.7E-34 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS18795 e1400316ab9e1cb8dfd06672dbb941ef 399 PANTHER PTHR24220 5 15 5.1E-157 T 22-04-2016 HRM2_RS18795 e1400316ab9e1cb8dfd06672dbb941ef 399 PANTHER PTHR24220 40 283 5.1E-157 T 22-04-2016 HRM2_RS18795 e1400316ab9e1cb8dfd06672dbb941ef 399 Pfam PF00571 CBS domain 278 327 0.0046 T 22-04-2016 IPR000644 CBS domain HRM2_RS18795 e1400316ab9e1cb8dfd06672dbb941ef 399 Pfam PF00571 CBS domain 341 391 0.002 T 22-04-2016 IPR000644 CBS domain HRM2_RS18795 e1400316ab9e1cb8dfd06672dbb941ef 399 SUPERFAMILY SSF52540 39 269 4.49E-75 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18795 e1400316ab9e1cb8dfd06672dbb941ef 399 SMART SM00116 344 391 0.0023 T 22-04-2016 IPR000644 CBS domain HRM2_RS18795 e1400316ab9e1cb8dfd06672dbb941ef 399 SMART SM00116 283 331 17.0 T 22-04-2016 IPR000644 CBS domain HRM2_RS18795 e1400316ab9e1cb8dfd06672dbb941ef 399 PANTHER PTHR24220:SF374 5 15 5.1E-157 T 22-04-2016 HRM2_RS18795 e1400316ab9e1cb8dfd06672dbb941ef 399 PANTHER PTHR24220:SF374 40 283 5.1E-157 T 22-04-2016 HRM2_RS18795 e1400316ab9e1cb8dfd06672dbb941ef 399 Gene3D G3DSA:3.10.580.10 271 392 4.1E-18 T 22-04-2016 HRM2_RS18795 e1400316ab9e1cb8dfd06672dbb941ef 399 SMART SM00382 52 249 4.3E-20 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS20315 7502ef4f1c575d647d6742920b60686e 638 Gene3D G3DSA:3.40.449.10 36 261 1.5E-39 T 22-04-2016 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 HRM2_RS20315 7502ef4f1c575d647d6742920b60686e 638 Pfam PF00821 Phosphoenolpyruvate carboxykinase 51 633 4.4E-141 T 22-04-2016 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00138 HRM2_RS20315 7502ef4f1c575d647d6742920b60686e 638 PANTHER PTHR11561:SF0 47 637 2.3E-86 T 22-04-2016 HRM2_RS20315 7502ef4f1c575d647d6742920b60686e 638 Gene3D G3DSA:3.90.228.20 419 634 5.0E-57 T 22-04-2016 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 HRM2_RS20315 7502ef4f1c575d647d6742920b60686e 638 Gene3D G3DSA:3.90.228.20 266 315 5.0E-57 T 22-04-2016 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 HRM2_RS20315 7502ef4f1c575d647d6742920b60686e 638 Gene3D G3DSA:2.170.8.10 316 415 3.1E-17 T 22-04-2016 HRM2_RS20315 7502ef4f1c575d647d6742920b60686e 638 PIRSF PIRSF001348 27 638 1.7E-101 T 22-04-2016 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00138 HRM2_RS20315 7502ef4f1c575d647d6742920b60686e 638 PANTHER PTHR11561 47 637 2.3E-86 T 22-04-2016 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00138 HRM2_RS20315 7502ef4f1c575d647d6742920b60686e 638 SUPERFAMILY SSF68923 31 260 1.99E-40 T 22-04-2016 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 HRM2_RS20315 7502ef4f1c575d647d6742920b60686e 638 SUPERFAMILY SSF53795 266 634 8.7E-90 T 22-04-2016 HRM2_RS21385 1925986032b7d4ed75202e27b45a4c6c 471 PIRSF PIRSF000350 1 436 7.4E-51 T 22-04-2016 HRM2_RS21385 1925986032b7d4ed75202e27b45a4c6c 471 Gene3D G3DSA:3.50.50.60 4 135 1.1E-23 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS21385 1925986032b7d4ed75202e27b45a4c6c 471 Gene3D G3DSA:3.30.390.30 336 450 4.5E-21 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HRM2_RS21385 1925986032b7d4ed75202e27b45a4c6c 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 253 267 8.3E-38 T 22-04-2016 HRM2_RS21385 1925986032b7d4ed75202e27b45a4c6c 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 8.3E-38 T 22-04-2016 HRM2_RS21385 1925986032b7d4ed75202e27b45a4c6c 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 399 414 8.3E-38 T 22-04-2016 HRM2_RS21385 1925986032b7d4ed75202e27b45a4c6c 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 8.3E-38 T 22-04-2016 HRM2_RS21385 1925986032b7d4ed75202e27b45a4c6c 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 304 8.3E-38 T 22-04-2016 HRM2_RS21385 1925986032b7d4ed75202e27b45a4c6c 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 135 144 8.3E-38 T 22-04-2016 HRM2_RS21385 1925986032b7d4ed75202e27b45a4c6c 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 333 354 8.3E-38 T 22-04-2016 HRM2_RS21385 1925986032b7d4ed75202e27b45a4c6c 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 421 441 8.3E-38 T 22-04-2016 HRM2_RS21385 1925986032b7d4ed75202e27b45a4c6c 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 171 196 8.3E-38 T 22-04-2016 HRM2_RS21385 1925986032b7d4ed75202e27b45a4c6c 471 Gene3D G3DSA:3.50.50.60 136 324 1.1E-29 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS21385 1925986032b7d4ed75202e27b45a4c6c 471 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 310 1.7E-32 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS21385 1925986032b7d4ed75202e27b45a4c6c 471 SUPERFAMILY SSF51905 5 364 2.68E-34 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS21385 1925986032b7d4ed75202e27b45a4c6c 471 PANTHER PTHR22912:SF176 4 450 3.3E-106 T 22-04-2016 HRM2_RS21385 1925986032b7d4ed75202e27b45a4c6c 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.2E-14 T 22-04-2016 HRM2_RS21385 1925986032b7d4ed75202e27b45a4c6c 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 189 1.2E-14 T 22-04-2016 HRM2_RS21385 1925986032b7d4ed75202e27b45a4c6c 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 252 268 1.2E-14 T 22-04-2016 HRM2_RS21385 1925986032b7d4ed75202e27b45a4c6c 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 1.2E-14 T 22-04-2016 HRM2_RS21385 1925986032b7d4ed75202e27b45a4c6c 471 PANTHER PTHR22912 4 450 3.3E-106 T 22-04-2016 HRM2_RS21385 1925986032b7d4ed75202e27b45a4c6c 471 SUPERFAMILY SSF55424 338 450 5.33E-21 T 22-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 HRM2_RS21385 1925986032b7d4ed75202e27b45a4c6c 471 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 339 446 7.8E-17 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HRM2_RS23525 42ea342bb85cd6db6db4bc0f67f1c239 326 Gene3D G3DSA:3.30.390.50 241 312 4.7E-6 T 22-04-2016 HRM2_RS23525 42ea342bb85cd6db6db4bc0f67f1c239 326 PANTHER PTHR12561 1 312 1.1E-72 T 22-04-2016 HRM2_RS23525 42ea342bb85cd6db6db4bc0f67f1c239 326 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 4 307 2.8E-68 T 22-04-2016 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 UniPathway: UPA00537|UniPathway: UPA00537 HRM2_RS23525 42ea342bb85cd6db6db4bc0f67f1c239 326 SUPERFAMILY SSF82649 240 318 1.73E-6 T 22-04-2016 HRM2_RS23525 42ea342bb85cd6db6db4bc0f67f1c239 326 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 257 311 2.6E-5 T 22-04-2016 IPR019491 Lipoate protein ligase, C-terminal UniPathway: UPA00537|UniPathway: UPA00537 HRM2_RS23525 42ea342bb85cd6db6db4bc0f67f1c239 326 Gene3D G3DSA:3.90.1550.10 4 238 4.2E-64 T 22-04-2016 HRM2_RS23525 42ea342bb85cd6db6db4bc0f67f1c239 326 PANTHER PTHR12561:SF3 1 312 1.1E-72 T 22-04-2016 HRM2_RS23525 42ea342bb85cd6db6db4bc0f67f1c239 326 SUPERFAMILY SSF55681 1 240 2.07E-63 T 22-04-2016 HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 SUPERFAMILY SSF82866 294 497 4.32E-41 T 22-04-2016 HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 Gene3D G3DSA:1.10.3850.10 282 499 2.6E-65 T 22-04-2016 HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 Gene3D G3DSA:1.10.3850.10 926 1150 1.1E-52 T 22-04-2016 HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 SUPERFAMILY SSF82866 920 1155 1.02E-48 T 22-04-2016 HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 Pfam PF00873 AcrB/AcrD/AcrF family 5 501 5.4E-126 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 Pfam PF00873 AcrB/AcrD/AcrF family 565 687 2.1E-17 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 Pfam PF00873 AcrB/AcrD/AcrF family 765 1147 2.7E-80 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 SUPERFAMILY SSF82693 271 328 1.1E-21 T 22-04-2016 HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 SUPERFAMILY SSF82693 137 184 1.1E-21 T 22-04-2016 HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 SUPERFAMILY SSF82714 185 269 3.92E-17 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 PANTHER PTHR32063:SF19 553 695 0.0 T 22-04-2016 HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 PANTHER PTHR32063:SF19 756 1159 0.0 T 22-04-2016 HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 PANTHER PTHR32063:SF19 2 503 0.0 T 22-04-2016 HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 Gene3D G3DSA:3.30.70.1430 46 141 2.3E-22 T 22-04-2016 HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 SUPERFAMILY SSF82714 839 919 1.57E-13 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 Gene3D G3DSA:3.30.2090.10 839 919 1.2E-14 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 Gene3D G3DSA:3.30.2090.10 185 269 1.6E-17 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 SUPERFAMILY SSF82693 46 127 6.02E-20 T 22-04-2016 HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 3.0E-30 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 3.0E-30 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 PRINTS PR00702 Acriflavin resistance protein family signature 361 382 3.0E-30 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 PRINTS PR00702 Acriflavin resistance protein family signature 389 413 3.0E-30 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 PRINTS PR00702 Acriflavin resistance protein family signature 334 357 3.0E-30 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 3.0E-30 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 3.0E-30 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 PANTHER PTHR32063 553 695 0.0 T 22-04-2016 HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 PANTHER PTHR32063 756 1159 0.0 T 22-04-2016 HRM2_RS00205 8553c19aadaf95cb591ed69fb9533a48 1163 PANTHER PTHR32063 2 503 0.0 T 22-04-2016 HRM2_RS01095 443651577c8e0d86e3b1a0a41a60bf00 247 PANTHER PTHR21091:SF9 1 84 6.3E-39 T 22-04-2016 HRM2_RS01095 443651577c8e0d86e3b1a0a41a60bf00 247 PANTHER PTHR21091:SF9 103 192 6.3E-39 T 22-04-2016 HRM2_RS01095 443651577c8e0d86e3b1a0a41a60bf00 247 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 2 241 2.6E-86 T 22-04-2016 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 HRM2_RS01095 443651577c8e0d86e3b1a0a41a60bf00 247 PANTHER PTHR21091 1 84 6.3E-39 T 22-04-2016 HRM2_RS01095 443651577c8e0d86e3b1a0a41a60bf00 247 PANTHER PTHR21091 103 192 6.3E-39 T 22-04-2016 HRM2_RS01095 443651577c8e0d86e3b1a0a41a60bf00 247 Gene3D G3DSA:3.40.1010.10 2 115 1.2E-20 T 22-04-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 HRM2_RS01095 443651577c8e0d86e3b1a0a41a60bf00 247 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 210 1.1E-28 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 HRM2_RS01095 443651577c8e0d86e3b1a0a41a60bf00 247 Gene3D G3DSA:3.30.950.10 116 230 7.9E-14 T 22-04-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 HRM2_RS01095 443651577c8e0d86e3b1a0a41a60bf00 247 SUPERFAMILY SSF53790 4 245 3.66E-44 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 HRM2_RS14860 1ab0c6e1e3a31c419eaef6962ada095d 445 SUPERFAMILY SSF52172 1 186 4.41E-42 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS14860 1ab0c6e1e3a31c419eaef6962ada095d 445 Gene3D G3DSA:3.40.50.300 140 314 3.1E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14860 1ab0c6e1e3a31c419eaef6962ada095d 445 Pfam PF00072 Response regulator receiver domain 4 110 9.3E-26 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS14860 1ab0c6e1e3a31c419eaef6962ada095d 445 PANTHER PTHR32071 1 444 9.9E-179 T 22-04-2016 HRM2_RS14860 1ab0c6e1e3a31c419eaef6962ada095d 445 Pfam PF00158 Sigma-54 interaction domain 143 308 1.1E-68 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS14860 1ab0c6e1e3a31c419eaef6962ada095d 445 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 411 428 4.3E-5 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS14860 1ab0c6e1e3a31c419eaef6962ada095d 445 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 428 445 4.3E-5 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS14860 1ab0c6e1e3a31c419eaef6962ada095d 445 Gene3D G3DSA:3.40.50.2300 3 133 1.4E-34 T 22-04-2016 HRM2_RS14860 1ab0c6e1e3a31c419eaef6962ada095d 445 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 228 243 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS14860 1ab0c6e1e3a31c419eaef6962ada095d 445 SUPERFAMILY SSF52540 142 380 1.21E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14860 1ab0c6e1e3a31c419eaef6962ada095d 445 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 166 179 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS14860 1ab0c6e1e3a31c419eaef6962ada095d 445 Pfam PF02954 Bacterial regulatory protein, Fis family 408 440 1.0E-4 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS14860 1ab0c6e1e3a31c419eaef6962ada095d 445 Gene3D G3DSA:1.10.10.60 404 443 3.8E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS14860 1ab0c6e1e3a31c419eaef6962ada095d 445 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 352 361 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS14860 1ab0c6e1e3a31c419eaef6962ada095d 445 SUPERFAMILY SSF46689 352 444 1.97E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS14860 1ab0c6e1e3a31c419eaef6962ada095d 445 SMART SM00382 162 305 3.9E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS14860 1ab0c6e1e3a31c419eaef6962ada095d 445 SMART SM00448 2 113 7.1E-34 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS14860 1ab0c6e1e3a31c419eaef6962ada095d 445 Gene3D G3DSA:1.10.8.60 315 381 7.6E-22 T 22-04-2016 HRM2_RS20280 06a592d4514bd254dc11128ee5a63581 566 SUPERFAMILY SSF53323 7 212 8.5E-33 T 22-04-2016 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 HRM2_RS20280 06a592d4514bd254dc11128ee5a63581 566 PANTHER PTHR32154:SF20 403 565 5.4E-184 T 22-04-2016 HRM2_RS20280 06a592d4514bd254dc11128ee5a63581 566 PANTHER PTHR32154:SF20 4 373 5.4E-184 T 22-04-2016 HRM2_RS20280 06a592d4514bd254dc11128ee5a63581 566 PANTHER PTHR32154 403 565 5.4E-184 T 22-04-2016 HRM2_RS20280 06a592d4514bd254dc11128ee5a63581 566 PANTHER PTHR32154 4 373 5.4E-184 T 22-04-2016 HRM2_RS20280 06a592d4514bd254dc11128ee5a63581 566 SUPERFAMILY SSF52518 189 448 2.13E-60 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS20280 06a592d4514bd254dc11128ee5a63581 566 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 13 171 4.9E-30 T 22-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HRM2_RS20280 06a592d4514bd254dc11128ee5a63581 566 Gene3D G3DSA:3.40.50.920 465 564 3.9E-11 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HRM2_RS20280 06a592d4514bd254dc11128ee5a63581 566 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 5 560 8.0E-178 T 22-04-2016 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969|UniPathway: UPA00223 HRM2_RS20280 06a592d4514bd254dc11128ee5a63581 566 Gene3D G3DSA:3.40.50.970 183 370 7.3E-67 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS20280 06a592d4514bd254dc11128ee5a63581 566 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 203 441 1.2E-55 T 22-04-2016 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 HRM2_RS20280 06a592d4514bd254dc11128ee5a63581 566 SUPERFAMILY SSF52922 465 564 3.28E-18 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HRM2_RS20280 06a592d4514bd254dc11128ee5a63581 566 Gene3D G3DSA:3.40.920.10 7 176 5.0E-30 T 22-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HRM2_RS14615 6982b91c5875850a699ce175cfdbb4aa 382 Gene3D G3DSA:3.40.50.300 1 240 5.5E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14615 6982b91c5875850a699ce175cfdbb4aa 382 SMART SM00382 30 217 4.5E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS14615 6982b91c5875850a699ce175cfdbb4aa 382 Gene3D G3DSA:3.10.580.10 251 365 2.5E-15 T 22-04-2016 HRM2_RS14615 6982b91c5875850a699ce175cfdbb4aa 382 Pfam PF00571 CBS domain 311 365 2.5E-4 T 22-04-2016 IPR000644 CBS domain HRM2_RS14615 6982b91c5875850a699ce175cfdbb4aa 382 Pfam PF00005 ABC transporter 21 167 1.1E-32 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS14615 6982b91c5875850a699ce175cfdbb4aa 382 PANTHER PTHR24220:SF350 3 272 3.4E-133 T 22-04-2016 HRM2_RS14615 6982b91c5875850a699ce175cfdbb4aa 382 SUPERFAMILY SSF52540 1 243 8.69E-72 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14615 6982b91c5875850a699ce175cfdbb4aa 382 SUPERFAMILY SSF54631 249 375 1.34E-17 T 22-04-2016 HRM2_RS14615 6982b91c5875850a699ce175cfdbb4aa 382 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS14615 6982b91c5875850a699ce175cfdbb4aa 382 PANTHER PTHR24220 3 272 3.4E-133 T 22-04-2016 HRM2_RS14615 6982b91c5875850a699ce175cfdbb4aa 382 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 15 367 9.8E-100 T 22-04-2016 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 SUPERFAMILY SSF56719 397 563 8.89E-86 T 22-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 SUPERFAMILY SSF56719 734 799 8.89E-86 T 22-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 ProSitePatterns PS00177 DNA topoisomerase II signature. 425 433 - T 22-04-2016 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 PANTHER PTHR10169 725 807 4.7E-291 T 22-04-2016 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 PANTHER PTHR10169 1 556 4.7E-291 T 22-04-2016 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 SUPERFAMILY SSF54211 224 394 1.73E-55 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 Pfam PF01751 Toprim domain 422 533 1.4E-17 T 22-04-2016 IPR006171 Toprim domain HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 PRINTS PR01159 DNA gyrase subunit B signature 184 199 2.2E-68 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 PRINTS PR01159 DNA gyrase subunit B signature 199 212 2.2E-68 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 PRINTS PR01159 DNA gyrase subunit B signature 363 377 2.2E-68 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 PRINTS PR01159 DNA gyrase subunit B signature 473 482 2.2E-68 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 PRINTS PR01159 DNA gyrase subunit B signature 315 331 2.2E-68 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 PRINTS PR01159 DNA gyrase subunit B signature 777 793 2.2E-68 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 PRINTS PR01159 DNA gyrase subunit B signature 223 245 2.2E-68 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 PRINTS PR01159 DNA gyrase subunit B signature 10 20 2.2E-68 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 PRINTS PR01159 DNA gyrase subunit B signature 761 773 2.2E-68 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 PRINTS PR01159 DNA gyrase subunit B signature 377 397 2.2E-68 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 Gene3D G3DSA:3.30.565.10 10 221 1.8E-88 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 PRINTS PR00418 DNA topoisomerase II family signature 39 54 1.7E-72 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 PRINTS PR00418 DNA topoisomerase II family signature 490 506 1.7E-72 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 PRINTS PR00418 DNA topoisomerase II family signature 508 525 1.7E-72 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 PRINTS PR00418 DNA topoisomerase II family signature 117 131 1.7E-72 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 PRINTS PR00418 DNA topoisomerase II family signature 270 283 1.7E-72 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 PRINTS PR00418 DNA topoisomerase II family signature 74 87 1.7E-72 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 PRINTS PR00418 DNA topoisomerase II family signature 528 540 1.7E-72 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 PRINTS PR00418 DNA topoisomerase II family signature 423 437 1.7E-72 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 PRINTS PR00418 DNA topoisomerase II family signature 740 756 1.7E-72 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 SMART SM00433 39 801 1.4E-275 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 7 808 90.845 T 22-04-2016 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 Pfam PF00204 DNA gyrase B 224 393 6.6E-60 T 22-04-2016 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 SUPERFAMILY SSF55874 10 221 1.57E-69 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 735 797 5.5E-31 T 22-04-2016 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 Gene3D G3DSA:3.30.230.10 223 394 5.5E-69 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 Gene3D G3DSA:3.40.50.670 725 790 6.5E-95 T 22-04-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 Gene3D G3DSA:3.40.50.670 407 553 6.5E-95 T 22-04-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 38 178 1.4E-21 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 SMART SM00387 35 179 1.4E-23 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS00010 4a9b71dfc3749f6521cb52edb0638bc5 808 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 10 807 1.9E-293 T 22-04-2016 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HRM2_RS16630 22153d1dfa70034712a8a1adbe1e0682 257 Pfam PF00005 ABC transporter 18 160 2.6E-27 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS16630 22153d1dfa70034712a8a1adbe1e0682 257 Gene3D G3DSA:3.40.50.300 1 223 5.6E-63 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16630 22153d1dfa70034712a8a1adbe1e0682 257 PANTHER PTHR24220 3 220 3.8E-90 T 22-04-2016 HRM2_RS16630 22153d1dfa70034712a8a1adbe1e0682 257 PANTHER PTHR24220:SF160 3 220 3.8E-90 T 22-04-2016 HRM2_RS16630 22153d1dfa70034712a8a1adbe1e0682 257 SUPERFAMILY SSF52540 1 221 9.3E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16630 22153d1dfa70034712a8a1adbe1e0682 257 SMART SM00382 26 208 8.8E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS16630 22153d1dfa70034712a8a1adbe1e0682 257 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS13560 0e16733858bfe26b1397cdb86e1a079b 470 Pfam PF00158 Sigma-54 interaction domain 160 327 2.5E-66 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS13560 0e16733858bfe26b1397cdb86e1a079b 470 Gene3D G3DSA:1.10.10.60 423 467 2.8E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS13560 0e16733858bfe26b1397cdb86e1a079b 470 SUPERFAMILY SSF46689 374 467 2.28E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS13560 0e16733858bfe26b1397cdb86e1a079b 470 Gene3D G3DSA:3.40.50.300 157 333 6.8E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13560 0e16733858bfe26b1397cdb86e1a079b 470 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 448 468 8.2E-10 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS13560 0e16733858bfe26b1397cdb86e1a079b 470 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 431 448 8.2E-10 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS13560 0e16733858bfe26b1397cdb86e1a079b 470 Gene3D G3DSA:1.10.8.60 334 409 7.0E-23 T 22-04-2016 HRM2_RS13560 0e16733858bfe26b1397cdb86e1a079b 470 SMART SM00091 22 88 5.1E-7 T 22-04-2016 IPR000014 PAS domain HRM2_RS13560 0e16733858bfe26b1397cdb86e1a079b 470 Gene3D G3DSA:3.30.450.20 11 75 1.4E-11 T 22-04-2016 HRM2_RS13560 0e16733858bfe26b1397cdb86e1a079b 470 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 20 81 1.1E-5 T 22-04-2016 IPR000014 PAS domain HRM2_RS13560 0e16733858bfe26b1397cdb86e1a079b 470 SUPERFAMILY SSF55785 22 115 5.93E-14 T 22-04-2016 IPR000014 PAS domain HRM2_RS13560 0e16733858bfe26b1397cdb86e1a079b 470 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 247 262 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS13560 0e16733858bfe26b1397cdb86e1a079b 470 Pfam PF00989 PAS fold 23 108 2.3E-8 T 22-04-2016 IPR013767 PAS fold GO:0006355 HRM2_RS13560 0e16733858bfe26b1397cdb86e1a079b 470 SUPERFAMILY SSF52540 160 404 1.24E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13560 0e16733858bfe26b1397cdb86e1a079b 470 SMART SM00382 180 328 3.2E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS13560 0e16733858bfe26b1397cdb86e1a079b 470 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 374 383 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS13560 0e16733858bfe26b1397cdb86e1a079b 470 Pfam PF02954 Bacterial regulatory protein, Fis family 429 465 9.5E-12 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS13560 0e16733858bfe26b1397cdb86e1a079b 470 PANTHER PTHR32071 143 470 9.5E-146 T 22-04-2016 HRM2_RS12745 ab96ccd07ecbda0ba869c61b16eda6e1 244 SMART SM00028 53 86 1.5E-8 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS12745 ab96ccd07ecbda0ba869c61b16eda6e1 244 SMART SM00028 87 120 31.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS12745 ab96ccd07ecbda0ba869c61b16eda6e1 244 SMART SM00028 19 52 30.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS12745 ab96ccd07ecbda0ba869c61b16eda6e1 244 SMART SM00028 121 154 0.085 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS12745 ab96ccd07ecbda0ba869c61b16eda6e1 244 Gene3D G3DSA:3.30.70.1070 162 239 2.1E-13 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 HRM2_RS12745 ab96ccd07ecbda0ba869c61b16eda6e1 244 Pfam PF05036 Sporulation related domain 165 239 7.6E-15 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 HRM2_RS12745 ab96ccd07ecbda0ba869c61b16eda6e1 244 Pfam PF00515 Tetratricopeptide repeat 53 85 6.1E-11 T 22-04-2016 IPR001440 Tetratricopeptide repeat 1 GO:0005515 HRM2_RS12745 ab96ccd07ecbda0ba869c61b16eda6e1 244 Gene3D G3DSA:1.25.40.10 100 158 4.9E-13 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS12745 ab96ccd07ecbda0ba869c61b16eda6e1 244 PANTHER PTHR23083 22 158 5.5E-23 T 22-04-2016 HRM2_RS12745 ab96ccd07ecbda0ba869c61b16eda6e1 244 Gene3D G3DSA:1.25.40.10 16 99 9.2E-23 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS12745 ab96ccd07ecbda0ba869c61b16eda6e1 244 SUPERFAMILY SSF110997 165 237 2.09E-11 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 HRM2_RS12745 ab96ccd07ecbda0ba869c61b16eda6e1 244 SUPERFAMILY SSF48452 219 231 4.14E-32 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS12745 ab96ccd07ecbda0ba869c61b16eda6e1 244 SUPERFAMILY SSF48452 18 157 4.14E-32 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS12745 ab96ccd07ecbda0ba869c61b16eda6e1 244 Pfam PF13181 Tetratricopeptide repeat 123 153 0.059 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS14510 a3035030e362b566c4dd7df57ce399c9 247 PANTHER PTHR39082 5 246 5.6E-34 T 22-04-2016 HRM2_RS14510 a3035030e362b566c4dd7df57ce399c9 247 Pfam PF02591 C4-type zinc ribbon domain 203 234 5.8E-10 T 22-04-2016 IPR003743 C4-type zinc ribbon domain HRM2_RS15130 9746b98026f80e23c008f7dc43bd7c09 359 SMART SM00244 60 240 4.7E-25 T 22-04-2016 IPR001107 Band 7 domain HRM2_RS15130 9746b98026f80e23c008f7dc43bd7c09 359 Pfam PF01145 SPFH domain / Band 7 family 64 256 1.3E-27 T 22-04-2016 IPR001107 Band 7 domain HRM2_RS15130 9746b98026f80e23c008f7dc43bd7c09 359 PRINTS PR00721 Stomatin signature 170 187 1.8E-8 T 22-04-2016 IPR001972 Stomatin family GO:0016020 HRM2_RS15130 9746b98026f80e23c008f7dc43bd7c09 359 PRINTS PR00721 Stomatin signature 135 156 1.8E-8 T 22-04-2016 IPR001972 Stomatin family GO:0016020 HRM2_RS15130 9746b98026f80e23c008f7dc43bd7c09 359 PRINTS PR00721 Stomatin signature 216 234 1.8E-8 T 22-04-2016 IPR001972 Stomatin family GO:0016020 HRM2_RS15130 9746b98026f80e23c008f7dc43bd7c09 359 PRINTS PR00721 Stomatin signature 235 256 1.8E-8 T 22-04-2016 IPR001972 Stomatin family GO:0016020 HRM2_RS15130 9746b98026f80e23c008f7dc43bd7c09 359 PANTHER PTHR10264 135 343 3.1E-72 T 22-04-2016 IPR001972 Stomatin family GO:0016020 HRM2_RS15130 9746b98026f80e23c008f7dc43bd7c09 359 PANTHER PTHR10264 46 114 3.1E-72 T 22-04-2016 IPR001972 Stomatin family GO:0016020 HRM2_RS15130 9746b98026f80e23c008f7dc43bd7c09 359 SUPERFAMILY SSF117892 130 247 3.92E-22 T 22-04-2016 IPR001107 Band 7 domain HRM2_RS15130 9746b98026f80e23c008f7dc43bd7c09 359 TIGRFAM TIGR01933 hflK: HflK protein 62 341 1.5E-77 T 22-04-2016 IPR010201 HflK GO:0016021 HRM2_RS15130 9746b98026f80e23c008f7dc43bd7c09 359 PANTHER PTHR10264:SF51 135 343 3.1E-72 T 22-04-2016 IPR010201 HflK GO:0016021 HRM2_RS15130 9746b98026f80e23c008f7dc43bd7c09 359 PANTHER PTHR10264:SF51 46 114 3.1E-72 T 22-04-2016 IPR010201 HflK GO:0016021 HRM2_RS01870 d47c47e5fa7c41db23a23f94e4ed5967 493 SUPERFAMILY SSF55785 11 123 1.92E-10 T 22-04-2016 IPR000014 PAS domain HRM2_RS01870 d47c47e5fa7c41db23a23f94e4ed5967 493 Pfam PF02954 Bacterial regulatory protein, Fis family 444 488 2.0E-9 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS01870 d47c47e5fa7c41db23a23f94e4ed5967 493 Gene3D G3DSA:3.40.50.300 186 361 2.5E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01870 d47c47e5fa7c41db23a23f94e4ed5967 493 Gene3D G3DSA:1.10.10.60 415 490 1.4E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS01870 d47c47e5fa7c41db23a23f94e4ed5967 493 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 8 128 1.3E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS01870 d47c47e5fa7c41db23a23f94e4ed5967 493 SUPERFAMILY SSF46689 400 490 2.46E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS01870 d47c47e5fa7c41db23a23f94e4ed5967 493 Gene3D G3DSA:1.10.8.60 362 414 8.0E-20 T 22-04-2016 HRM2_RS01870 d47c47e5fa7c41db23a23f94e4ed5967 493 PANTHER PTHR32071 153 492 7.1E-144 T 22-04-2016 HRM2_RS01870 d47c47e5fa7c41db23a23f94e4ed5967 493 SMART SM00382 209 353 1.5E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS01870 d47c47e5fa7c41db23a23f94e4ed5967 493 Pfam PF00158 Sigma-54 interaction domain 189 355 4.9E-69 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS01870 d47c47e5fa7c41db23a23f94e4ed5967 493 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 213 226 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS01870 d47c47e5fa7c41db23a23f94e4ed5967 493 PANTHER PTHR32071:SF16 153 492 7.1E-144 T 22-04-2016 HRM2_RS01870 d47c47e5fa7c41db23a23f94e4ed5967 493 Pfam PF08448 PAS fold 15 124 2.1E-7 T 22-04-2016 IPR013656 PAS fold-4 HRM2_RS01870 d47c47e5fa7c41db23a23f94e4ed5967 493 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 402 411 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS01870 d47c47e5fa7c41db23a23f94e4ed5967 493 Gene3D G3DSA:3.30.450.20 9 121 7.9E-10 T 22-04-2016 HRM2_RS01870 d47c47e5fa7c41db23a23f94e4ed5967 493 SUPERFAMILY SSF52540 188 426 9.04E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01870 d47c47e5fa7c41db23a23f94e4ed5967 493 SMART SM00091 7 74 1.7E-5 T 22-04-2016 IPR000014 PAS domain HRM2_RS05660 22be4cbd7d49362d1a61431a3a849016 228 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS05660 22be4cbd7d49362d1a61431a3a849016 228 Pfam PF00005 ABC transporter 23 170 6.3E-34 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS05660 22be4cbd7d49362d1a61431a3a849016 228 SUPERFAMILY SSF52540 7 221 8.52E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05660 22be4cbd7d49362d1a61431a3a849016 228 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 7 219 6.6E-81 T 22-04-2016 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 HRM2_RS05660 22be4cbd7d49362d1a61431a3a849016 228 PANTHER PTHR24220 9 221 3.0E-96 T 22-04-2016 HRM2_RS05660 22be4cbd7d49362d1a61431a3a849016 228 PANTHER PTHR24220:SF470 9 221 3.0E-96 T 22-04-2016 HRM2_RS05660 22be4cbd7d49362d1a61431a3a849016 228 Gene3D G3DSA:3.40.50.300 2 208 1.4E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05660 22be4cbd7d49362d1a61431a3a849016 228 SMART SM00382 32 223 1.2E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS04765 ce3f5f43f94040a04b7a8afd41689082 116 PRINTS PR00340 P-II protein signature 3 18 1.0E-17 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HRM2_RS04765 ce3f5f43f94040a04b7a8afd41689082 116 PRINTS PR00340 P-II protein signature 83 103 1.0E-17 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HRM2_RS04765 ce3f5f43f94040a04b7a8afd41689082 116 PRINTS PR00340 P-II protein signature 24 42 1.0E-17 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HRM2_RS04765 ce3f5f43f94040a04b7a8afd41689082 116 Gene3D G3DSA:3.30.70.120 4 105 3.8E-29 T 22-04-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal HRM2_RS04765 ce3f5f43f94040a04b7a8afd41689082 116 Pfam PF00543 Nitrogen regulatory protein P-II 5 105 8.3E-26 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HRM2_RS04765 ce3f5f43f94040a04b7a8afd41689082 116 SUPERFAMILY SSF54913 4 105 2.89E-27 T 22-04-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta HRM2_RS04765 ce3f5f43f94040a04b7a8afd41689082 116 PANTHER PTHR30115:SF13 1 102 1.3E-28 T 22-04-2016 HRM2_RS04765 ce3f5f43f94040a04b7a8afd41689082 116 PANTHER PTHR30115 1 102 1.3E-28 T 22-04-2016 HRM2_RS04765 ce3f5f43f94040a04b7a8afd41689082 116 SMART SM00938 5 105 5.1E-39 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HRM2_RS19945 cec6515b8fb5789d72f81fb83a985a6c 515 SUPERFAMILY SSF53187 192 506 2.1E-109 T 22-04-2016 HRM2_RS19945 cec6515b8fb5789d72f81fb83a985a6c 515 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 36 153 1.7E-15 T 22-04-2016 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 HRM2_RS19945 cec6515b8fb5789d72f81fb83a985a6c 515 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 354 361 - T 22-04-2016 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 HRM2_RS19945 cec6515b8fb5789d72f81fb83a985a6c 515 PRINTS PR00481 Cytosol aminopeptidase signature 291 312 2.7E-46 T 22-04-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 HRM2_RS19945 cec6515b8fb5789d72f81fb83a985a6c 515 PRINTS PR00481 Cytosol aminopeptidase signature 379 394 2.7E-46 T 22-04-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 HRM2_RS19945 cec6515b8fb5789d72f81fb83a985a6c 515 PRINTS PR00481 Cytosol aminopeptidase signature 269 286 2.7E-46 T 22-04-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 HRM2_RS19945 cec6515b8fb5789d72f81fb83a985a6c 515 PRINTS PR00481 Cytosol aminopeptidase signature 328 349 2.7E-46 T 22-04-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 HRM2_RS19945 cec6515b8fb5789d72f81fb83a985a6c 515 PRINTS PR00481 Cytosol aminopeptidase signature 350 370 2.7E-46 T 22-04-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 HRM2_RS19945 cec6515b8fb5789d72f81fb83a985a6c 515 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 195 500 1.3E-113 T 22-04-2016 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 HRM2_RS19945 cec6515b8fb5789d72f81fb83a985a6c 515 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 5 508 32.902 T 22-04-2016 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 HRM2_RS19945 cec6515b8fb5789d72f81fb83a985a6c 515 Gene3D G3DSA:3.40.630.10 183 506 9.6E-122 T 22-04-2016 HRM2_RS19945 cec6515b8fb5789d72f81fb83a985a6c 515 PANTHER PTHR11963:SF13 37 505 3.7E-160 T 22-04-2016 HRM2_RS19945 cec6515b8fb5789d72f81fb83a985a6c 515 SUPERFAMILY SSF52949 9 181 3.65E-16 T 22-04-2016 HRM2_RS19945 cec6515b8fb5789d72f81fb83a985a6c 515 Gene3D G3DSA:3.40.220.10 12 159 6.6E-16 T 22-04-2016 HRM2_RS19945 cec6515b8fb5789d72f81fb83a985a6c 515 PANTHER PTHR11963 37 505 3.7E-160 T 22-04-2016 HRM2_RS08975 073bae8fec7278cdf5d5ad14883a8e07 138 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 4.4E-40 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HRM2_RS08975 073bae8fec7278cdf5d5ad14883a8e07 138 PRINTS PR01243 Nucleoside diphosphate kinase signature 89 105 4.4E-40 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HRM2_RS08975 073bae8fec7278cdf5d5ad14883a8e07 138 PRINTS PR01243 Nucleoside diphosphate kinase signature 112 131 4.4E-40 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HRM2_RS08975 073bae8fec7278cdf5d5ad14883a8e07 138 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 4.4E-40 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HRM2_RS08975 073bae8fec7278cdf5d5ad14883a8e07 138 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 4.4E-40 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HRM2_RS08975 073bae8fec7278cdf5d5ad14883a8e07 138 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 112 120 - T 22-04-2016 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HRM2_RS08975 073bae8fec7278cdf5d5ad14883a8e07 138 Gene3D G3DSA:3.30.70.141 1 137 9.9E-58 T 22-04-2016 HRM2_RS08975 073bae8fec7278cdf5d5ad14883a8e07 138 Pfam PF00334 Nucleoside diphosphate kinase 2 136 1.1E-56 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HRM2_RS08975 073bae8fec7278cdf5d5ad14883a8e07 138 PANTHER PTHR11349 1 137 1.8E-71 T 22-04-2016 HRM2_RS08975 073bae8fec7278cdf5d5ad14883a8e07 138 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 136 35.023 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HRM2_RS08975 073bae8fec7278cdf5d5ad14883a8e07 138 SMART SM00562 1 138 9.0E-81 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HRM2_RS08975 073bae8fec7278cdf5d5ad14883a8e07 138 SUPERFAMILY SSF54919 1 137 2.36E-57 T 22-04-2016 HRM2_RS20240 55d3bba832867d1bf994e5db355186b7 153 SUPERFAMILY SSF47240 7 147 3.15E-27 T 22-04-2016 IPR009078 Ferritin-like superfamily HRM2_RS20240 55d3bba832867d1bf994e5db355186b7 153 Pfam PF02915 Rubrerythrin 94 150 4.0E-8 T 22-04-2016 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 HRM2_RS20240 55d3bba832867d1bf994e5db355186b7 153 Pfam PF02915 Rubrerythrin 8 66 3.9E-11 T 22-04-2016 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 HRM2_RS20240 55d3bba832867d1bf994e5db355186b7 153 Gene3D G3DSA:1.20.1260.10 5 146 1.7E-29 T 22-04-2016 IPR012347 Ferritin-related HRM2_RS13720 07e6ee50cb8c4e5ea205b31f50b214f8 259 SMART SM00382 39 229 4.5E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS13720 07e6ee50cb8c4e5ea205b31f50b214f8 259 PANTHER PTHR24220 10 248 7.4E-94 T 22-04-2016 HRM2_RS13720 07e6ee50cb8c4e5ea205b31f50b214f8 259 Gene3D G3DSA:3.40.50.300 4 242 5.6E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13720 07e6ee50cb8c4e5ea205b31f50b214f8 259 Pfam PF00005 ABC transporter 31 171 4.3E-27 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS13720 07e6ee50cb8c4e5ea205b31f50b214f8 259 SUPERFAMILY SSF52540 8 234 3.03E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13720 07e6ee50cb8c4e5ea205b31f50b214f8 259 PANTHER PTHR24220:SF160 10 248 7.4E-94 T 22-04-2016 HRM2_RS01685 8ea15fe4647320f23979917ef068fde6 812 SUPERFAMILY SSF50692 607 646 2.49E-41 T 22-04-2016 IPR009010 Aspartate decarboxylase-like domain HRM2_RS01685 8ea15fe4647320f23979917ef068fde6 812 SUPERFAMILY SSF50692 674 804 2.49E-41 T 22-04-2016 IPR009010 Aspartate decarboxylase-like domain HRM2_RS01685 8ea15fe4647320f23979917ef068fde6 812 Gene3D G3DSA:2.40.40.20 602 804 3.2E-46 T 22-04-2016 HRM2_RS01685 8ea15fe4647320f23979917ef068fde6 812 TIGRFAM TIGR01553 formate-DH-alph: formate dehydrogenase-N alpha subunit 1 803 0.0 T 22-04-2016 IPR006443 Formate dehydrogenase-N, alpha subunit GO:0008863|GO:0009055|GO:0043546|GO:0045333|GO:0047111 HRM2_RS01685 8ea15fe4647320f23979917ef068fde6 812 PANTHER PTHR11615:SF126 321 479 2.2E-164 T 22-04-2016 HRM2_RS01685 8ea15fe4647320f23979917ef068fde6 812 PANTHER PTHR11615:SF126 209 278 2.2E-164 T 22-04-2016 HRM2_RS01685 8ea15fe4647320f23979917ef068fde6 812 PANTHER PTHR11615:SF126 1 181 2.2E-164 T 22-04-2016 HRM2_RS01685 8ea15fe4647320f23979917ef068fde6 812 PANTHER PTHR11615:SF126 576 645 2.2E-164 T 22-04-2016 HRM2_RS01685 8ea15fe4647320f23979917ef068fde6 812 PANTHER PTHR11615:SF126 665 805 2.2E-164 T 22-04-2016 HRM2_RS01685 8ea15fe4647320f23979917ef068fde6 812 SUPERFAMILY SSF53706 1 637 1.96E-219 T 22-04-2016 HRM2_RS01685 8ea15fe4647320f23979917ef068fde6 812 Gene3D G3DSA:3.40.228.10 1 104 7.8E-67 T 22-04-2016 HRM2_RS01685 8ea15fe4647320f23979917ef068fde6 812 Gene3D G3DSA:3.40.228.10 148 261 7.8E-67 T 22-04-2016 HRM2_RS01685 8ea15fe4647320f23979917ef068fde6 812 Pfam PF01568 Molydopterin dinucleotide binding domain 679 797 1.2E-17 T 22-04-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 HRM2_RS01685 8ea15fe4647320f23979917ef068fde6 812 Pfam PF00384 Molybdopterin oxidoreductase 2 431 9.6E-24 T 22-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 HRM2_RS01685 8ea15fe4647320f23979917ef068fde6 812 PANTHER PTHR11615 321 479 2.2E-164 T 22-04-2016 HRM2_RS01685 8ea15fe4647320f23979917ef068fde6 812 PANTHER PTHR11615 209 278 2.2E-164 T 22-04-2016 HRM2_RS01685 8ea15fe4647320f23979917ef068fde6 812 PANTHER PTHR11615 1 181 2.2E-164 T 22-04-2016 HRM2_RS01685 8ea15fe4647320f23979917ef068fde6 812 PANTHER PTHR11615 576 645 2.2E-164 T 22-04-2016 HRM2_RS01685 8ea15fe4647320f23979917ef068fde6 812 PANTHER PTHR11615 665 805 2.2E-164 T 22-04-2016 HRM2_RS01685 8ea15fe4647320f23979917ef068fde6 812 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 717 744 - T 22-04-2016 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 HRM2_RS01685 8ea15fe4647320f23979917ef068fde6 812 Gene3D G3DSA:3.40.50.740 321 463 5.7E-49 T 22-04-2016 HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 SUPERFAMILY SSF52172 940 1060 2.28E-26 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 SUPERFAMILY SSF55785 421 546 1.05E-25 T 22-04-2016 IPR000014 PAS domain HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 SUPERFAMILY SSF55785 545 667 3.14E-18 T 22-04-2016 IPR000014 PAS domain HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 PRINTS PR00344 Bacterial sensor protein C-terminal signature 850 864 1.4E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 PRINTS PR00344 Bacterial sensor protein C-terminal signature 905 918 1.4E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 PRINTS PR00344 Bacterial sensor protein C-terminal signature 868 878 1.4E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 PRINTS PR00344 Bacterial sensor protein C-terminal signature 881 899 1.4E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 Gene3D G3DSA:3.30.565.10 744 921 5.7E-37 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 Gene3D G3DSA:3.40.50.2300 939 1061 4.1E-28 T 22-04-2016 HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 SMART SM00086 507 548 4.2E-6 T 22-04-2016 IPR001610 PAC motif HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 SMART SM00086 626 669 40.0 T 22-04-2016 IPR001610 PAC motif HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 Pfam PF08269 Cache domain 35 335 8.6E-82 T 22-04-2016 IPR004010 Double Cache domain 2 HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 SUPERFAMILY SSF55874 747 921 7.47E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 Pfam PF00072 Response regulator receiver domain 943 1054 6.9E-19 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 SMART SM01049 72 166 5.7E-13 T 22-04-2016 IPR033480 Single Cache domain 2 HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 Pfam PF00512 His Kinase A (phospho-acceptor) domain 692 754 8.2E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 PANTHER PTHR24423:SF458 114 1064 8.4E-183 T 22-04-2016 HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 Gene3D G3DSA:3.30.450.20 433 571 3.4E-28 T 22-04-2016 HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 Pfam PF08448 PAS fold 566 671 2.6E-8 T 22-04-2016 IPR013656 PAS fold-4 HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 Gene3D G3DSA:1.10.287.130 685 743 1.3E-5 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 799 919 7.8E-17 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 PANTHER PTHR24423 114 1064 8.4E-183 T 22-04-2016 HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 Pfam PF00989 PAS fold 436 545 9.2E-14 T 22-04-2016 IPR013767 PAS fold GO:0006355 HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 SMART SM00091 435 501 1.2E-10 T 22-04-2016 IPR000014 PAS domain HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 SMART SM00091 560 626 5.8E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 432 554 2.4E-24 T 22-04-2016 IPR000014 PAS domain HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 562 675 9.6E-10 T 22-04-2016 IPR000014 PAS domain HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 Gene3D G3DSA:3.30.450.20 67 220 2.1E-37 T 22-04-2016 HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 Gene3D G3DSA:3.30.450.20 221 335 1.6E-17 T 22-04-2016 HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 SMART SM00388 691 757 1.8E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 Gene3D G3DSA:3.30.450.20 572 684 5.8E-19 T 22-04-2016 HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 SUPERFAMILY SSF47384 680 754 1.28E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 SMART SM00448 941 1054 3.7E-16 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS25210 c190ca40595f974f5ea520b44d24461f 1065 SMART SM00387 798 921 8.6E-24 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS10750 a16b4b8e5138c3ac608e6a56217b6bb2 293 SUPERFAMILY SSF55920 48 292 3.79E-86 T 22-04-2016 IPR000994 Peptidase M24, structural domain HRM2_RS10750 a16b4b8e5138c3ac608e6a56217b6bb2 293 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 47 291 1.2E-91 T 22-04-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 HRM2_RS10750 a16b4b8e5138c3ac608e6a56217b6bb2 293 Hamap MF_01974 Methionine aminopeptidase [map]. 47 293 39.519 T 22-04-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 HRM2_RS10750 a16b4b8e5138c3ac608e6a56217b6bb2 293 Gene3D G3DSA:3.10.450.50 8 29 1.1E-8 T 22-04-2016 IPR032710 NTF2-like domain HRM2_RS10750 a16b4b8e5138c3ac608e6a56217b6bb2 293 PANTHER PTHR10804 44 291 5.6E-118 T 22-04-2016 HRM2_RS10750 a16b4b8e5138c3ac608e6a56217b6bb2 293 PRINTS PR00599 Methionine aminopeptidase-1 signature 235 247 2.2E-21 T 22-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase HRM2_RS10750 a16b4b8e5138c3ac608e6a56217b6bb2 293 PRINTS PR00599 Methionine aminopeptidase-1 signature 204 216 2.2E-21 T 22-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase HRM2_RS10750 a16b4b8e5138c3ac608e6a56217b6bb2 293 PRINTS PR00599 Methionine aminopeptidase-1 signature 112 125 2.2E-21 T 22-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase HRM2_RS10750 a16b4b8e5138c3ac608e6a56217b6bb2 293 PRINTS PR00599 Methionine aminopeptidase-1 signature 134 150 2.2E-21 T 22-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase HRM2_RS10750 a16b4b8e5138c3ac608e6a56217b6bb2 293 PANTHER PTHR10804:SF82 44 291 5.6E-118 T 22-04-2016 HRM2_RS10750 a16b4b8e5138c3ac608e6a56217b6bb2 293 SUPERFAMILY SSF103642 10 31 4.58E-8 T 22-04-2016 HRM2_RS10750 a16b4b8e5138c3ac608e6a56217b6bb2 293 Pfam PF02810 SEC-C motif 12 29 7.0E-10 T 22-04-2016 IPR004027 SEC-C motif HRM2_RS10750 a16b4b8e5138c3ac608e6a56217b6bb2 293 Gene3D G3DSA:3.90.230.10 48 292 1.1E-91 T 22-04-2016 IPR000994 Peptidase M24, structural domain HRM2_RS10750 a16b4b8e5138c3ac608e6a56217b6bb2 293 Pfam PF00557 Metallopeptidase family M24 57 284 5.7E-55 T 22-04-2016 IPR000994 Peptidase M24, structural domain HRM2_RS10750 a16b4b8e5138c3ac608e6a56217b6bb2 293 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 210 228 - T 22-04-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 HRM2_RS17150 f0ceac1a10bfbfef43cc1f682680ce3d 216 PANTHER PTHR10681 171 214 3.1E-55 T 22-04-2016 HRM2_RS17150 f0ceac1a10bfbfef43cc1f682680ce3d 216 PANTHER PTHR10681 2 150 3.1E-55 T 22-04-2016 HRM2_RS17150 f0ceac1a10bfbfef43cc1f682680ce3d 216 Gene3D G3DSA:3.40.30.10 41 214 3.4E-29 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS17150 f0ceac1a10bfbfef43cc1f682680ce3d 216 SUPERFAMILY SSF52833 43 214 4.55E-29 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS17150 f0ceac1a10bfbfef43cc1f682680ce3d 216 Pfam PF00578 AhpC/TSA family 46 190 9.6E-29 T 22-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 HRM2_RS17150 f0ceac1a10bfbfef43cc1f682680ce3d 216 PANTHER PTHR10681:SF70 171 214 3.1E-55 T 22-04-2016 HRM2_RS17150 f0ceac1a10bfbfef43cc1f682680ce3d 216 PANTHER PTHR10681:SF70 2 150 3.1E-55 T 22-04-2016 HRM2_RS05495 b24f507601ad8b8844ed6473313da9a4 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.7E-6 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HRM2_RS05495 b24f507601ad8b8844ed6473313da9a4 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.7E-6 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HRM2_RS05495 b24f507601ad8b8844ed6473313da9a4 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.7E-6 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HRM2_RS05495 b24f507601ad8b8844ed6473313da9a4 299 Pfam PF03466 LysR substrate binding domain 89 296 3.3E-42 T 22-04-2016 IPR005119 LysR, substrate-binding HRM2_RS05495 b24f507601ad8b8844ed6473313da9a4 299 Gene3D G3DSA:3.40.190.10 176 264 3.0E-16 T 22-04-2016 HRM2_RS05495 b24f507601ad8b8844ed6473313da9a4 299 Gene3D G3DSA:3.40.190.10 90 175 1.0E-14 T 22-04-2016 HRM2_RS05495 b24f507601ad8b8844ed6473313da9a4 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.2E-18 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HRM2_RS05495 b24f507601ad8b8844ed6473313da9a4 299 PANTHER PTHR30126:SF11 1 298 1.3E-87 T 22-04-2016 HRM2_RS05495 b24f507601ad8b8844ed6473313da9a4 299 SUPERFAMILY SSF53850 89 298 5.63E-40 T 22-04-2016 HRM2_RS05495 b24f507601ad8b8844ed6473313da9a4 299 Gene3D G3DSA:1.10.10.10 1 82 2.9E-25 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS05495 b24f507601ad8b8844ed6473313da9a4 299 SUPERFAMILY SSF46785 1 84 2.65E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS05495 b24f507601ad8b8844ed6473313da9a4 299 PANTHER PTHR30126 1 298 1.3E-87 T 22-04-2016 HRM2_RS15785 98e120c49b464f7db4f9f081fce690fc 244 SUPERFAMILY SSF46894 143 242 3.12E-19 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HRM2_RS15785 98e120c49b464f7db4f9f081fce690fc 244 Pfam PF00072 Response regulator receiver domain 9 118 1.2E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS15785 98e120c49b464f7db4f9f081fce690fc 244 SMART SM00448 7 118 2.8E-42 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS15785 98e120c49b464f7db4f9f081fce690fc 244 Pfam PF00486 Transcriptional regulatory protein, C terminal 168 241 5.6E-17 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HRM2_RS15785 98e120c49b464f7db4f9f081fce690fc 244 SMART SM00862 165 241 1.0E-13 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HRM2_RS15785 98e120c49b464f7db4f9f081fce690fc 244 Gene3D G3DSA:3.40.50.2300 4 127 6.9E-39 T 22-04-2016 HRM2_RS15785 98e120c49b464f7db4f9f081fce690fc 244 PANTHER PTHR26402:SF553 7 241 2.0E-74 T 22-04-2016 HRM2_RS15785 98e120c49b464f7db4f9f081fce690fc 244 PANTHER PTHR26402 7 241 2.0E-74 T 22-04-2016 HRM2_RS15785 98e120c49b464f7db4f9f081fce690fc 244 Gene3D G3DSA:1.10.10.10 145 243 1.3E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS15785 98e120c49b464f7db4f9f081fce690fc 244 SUPERFAMILY SSF52172 4 131 1.2E-39 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS14070 469576afe83fa33027d0676a44abe0f7 419 Pfam PF01979 Amidohydrolase family 59 409 4.6E-42 T 22-04-2016 IPR006680 Amidohydrolase-related GO:0016787 HRM2_RS14070 469576afe83fa33027d0676a44abe0f7 419 PANTHER PTHR11271 1 418 1.4E-128 T 22-04-2016 HRM2_RS14070 469576afe83fa33027d0676a44abe0f7 419 SUPERFAMILY SSF51556 62 366 8.01E-78 T 22-04-2016 IPR032466 Metal-dependent hydrolase HRM2_RS14070 469576afe83fa33027d0676a44abe0f7 419 SUPERFAMILY SSF51338 342 418 6.91E-11 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS14070 469576afe83fa33027d0676a44abe0f7 419 SUPERFAMILY SSF51338 7 71 2.46E-9 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS14070 469576afe83fa33027d0676a44abe0f7 419 Gene3D G3DSA:2.30.40.10 12 68 5.9E-6 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS14070 469576afe83fa33027d0676a44abe0f7 419 Gene3D G3DSA:3.20.20.140 69 365 2.2E-95 T 22-04-2016 HRM2_RS14070 469576afe83fa33027d0676a44abe0f7 419 PANTHER PTHR11271:SF6 1 418 1.4E-128 T 22-04-2016 IPR014311 Guanine deaminase GO:0006147|GO:0008270|GO:0008892 KEGG: 00230+3.5.4.3|MetaCyc: PWY-5497|MetaCyc: PWY-6606|MetaCyc: PWY-6608|MetaCyc: PWY-7442|UniPathway: UPA00603 HRM2_RS06830 b8fd86205173a7666f6ade3051791c15 360 SMART SM00382 28 211 2.0E-18 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS06830 b8fd86205173a7666f6ade3051791c15 360 SUPERFAMILY SSF52540 4 242 4.79E-86 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06830 b8fd86205173a7666f6ade3051791c15 360 SUPERFAMILY SSF50331 236 349 1.76E-10 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal HRM2_RS06830 b8fd86205173a7666f6ade3051791c15 360 Pfam PF00005 ABC transporter 19 161 6.3E-35 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS06830 b8fd86205173a7666f6ade3051791c15 360 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS06830 b8fd86205173a7666f6ade3051791c15 360 PANTHER PTHR24220 5 292 9.4E-141 T 22-04-2016 HRM2_RS06830 b8fd86205173a7666f6ade3051791c15 360 PANTHER PTHR24220:SF150 5 292 9.4E-141 T 22-04-2016 HRM2_RS06830 b8fd86205173a7666f6ade3051791c15 360 Pfam PF08402 TOBE domain 277 357 2.5E-10 T 22-04-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 HRM2_RS06830 b8fd86205173a7666f6ade3051791c15 360 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 34 357 3.3E-122 T 22-04-2016 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 HRM2_RS06830 b8fd86205173a7666f6ade3051791c15 360 Gene3D G3DSA:3.40.50.300 3 233 9.1E-77 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01195 9e38572241f16ada61a13b25631e3805 284 PANTHER PTHR30425:SF0 1 284 4.0E-101 T 22-04-2016 HRM2_RS01195 9e38572241f16ada61a13b25631e3805 284 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 17 279 2.2E-87 T 22-04-2016 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 HRM2_RS01195 9e38572241f16ada61a13b25631e3805 284 Gene3D G3DSA:1.10.3720.10 17 282 3.8E-40 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS01195 9e38572241f16ada61a13b25631e3805 284 SUPERFAMILY SSF161098 25 269 1.5E-36 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS01195 9e38572241f16ada61a13b25631e3805 284 PANTHER PTHR30425 1 284 4.0E-101 T 22-04-2016 HRM2_RS01195 9e38572241f16ada61a13b25631e3805 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 283 1.6E-22 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS08685 68181a5acea605aee9695e8685bb998e 429 Gene3D G3DSA:3.40.440.10 3 92 1.8E-65 T 22-04-2016 HRM2_RS08685 68181a5acea605aee9695e8685bb998e 429 Gene3D G3DSA:3.40.440.10 196 265 1.8E-65 T 22-04-2016 HRM2_RS08685 68181a5acea605aee9695e8685bb998e 429 Gene3D G3DSA:1.10.300.10 101 195 4.1E-35 T 22-04-2016 HRM2_RS08685 68181a5acea605aee9695e8685bb998e 429 Gene3D G3DSA:3.90.170.10 266 424 2.7E-70 T 22-04-2016 HRM2_RS08685 68181a5acea605aee9695e8685bb998e 429 PANTHER PTHR11846 3 427 3.0E-234 T 22-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 HRM2_RS08685 68181a5acea605aee9695e8685bb998e 429 Pfam PF00709 Adenylosuccinate synthetase 4 422 3.1E-178 T 22-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 HRM2_RS08685 68181a5acea605aee9695e8685bb998e 429 SMART SM00788 3 423 2.0E-274 T 22-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 HRM2_RS08685 68181a5acea605aee9695e8685bb998e 429 SUPERFAMILY SSF52540 2 428 7.33E-171 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08685 68181a5acea605aee9695e8685bb998e 429 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 22-04-2016 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 HRM2_RS08685 68181a5acea605aee9695e8685bb998e 429 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 426 7.8E-174 T 22-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 HRM2_RS08685 68181a5acea605aee9695e8685bb998e 429 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 132 143 - T 22-04-2016 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|UniPathway: UPA00075 HRM2_RS08685 68181a5acea605aee9695e8685bb998e 429 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 429 201.038 T 22-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 HRM2_RS17265 2e6b132bcbbc4245a5657dd6f43b3c8d 543 Pfam PF07969 Amidohydrolase family 54 536 7.1E-92 T 22-04-2016 IPR013108 Amidohydrolase 3 HRM2_RS17265 2e6b132bcbbc4245a5657dd6f43b3c8d 543 SUPERFAMILY SSF51556 65 126 4.09E-30 T 22-04-2016 IPR032466 Metal-dependent hydrolase HRM2_RS17265 2e6b132bcbbc4245a5657dd6f43b3c8d 543 SUPERFAMILY SSF51556 202 496 4.09E-30 T 22-04-2016 IPR032466 Metal-dependent hydrolase HRM2_RS17265 2e6b132bcbbc4245a5657dd6f43b3c8d 543 SUPERFAMILY SSF51338 7 66 2.39E-24 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS17265 2e6b132bcbbc4245a5657dd6f43b3c8d 543 SUPERFAMILY SSF51338 495 539 2.39E-24 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS17265 2e6b132bcbbc4245a5657dd6f43b3c8d 543 Gene3D G3DSA:3.20.20.140 204 477 4.3E-21 T 22-04-2016 HRM2_RS17265 2e6b132bcbbc4245a5657dd6f43b3c8d 543 PANTHER PTHR22642:SF2 6 538 1.1E-145 T 22-04-2016 HRM2_RS17265 2e6b132bcbbc4245a5657dd6f43b3c8d 543 Gene3D G3DSA:2.30.40.10 8 101 8.5E-16 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS17265 2e6b132bcbbc4245a5657dd6f43b3c8d 543 Gene3D G3DSA:2.30.40.10 478 540 1.8E-6 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS17265 2e6b132bcbbc4245a5657dd6f43b3c8d 543 PANTHER PTHR22642 6 538 1.1E-145 T 22-04-2016 HRM2_RS10095 d339f9969a4a8ef38f7029c95458af8a 249 SMART SM00382 30 217 1.8E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS10095 d339f9969a4a8ef38f7029c95458af8a 249 PIRSF PIRSF039085 2 244 2.0E-106 T 22-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 HRM2_RS10095 d339f9969a4a8ef38f7029c95458af8a 249 PANTHER PTHR24220 7 243 1.2E-125 T 22-04-2016 HRM2_RS10095 d339f9969a4a8ef38f7029c95458af8a 249 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS10095 d339f9969a4a8ef38f7029c95458af8a 249 SUPERFAMILY SSF52540 5 239 6.74E-77 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10095 d339f9969a4a8ef38f7029c95458af8a 249 Pfam PF00005 ABC transporter 22 169 5.8E-33 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS10095 d339f9969a4a8ef38f7029c95458af8a 249 PANTHER PTHR24220:SF327 7 243 1.2E-125 T 22-04-2016 HRM2_RS10095 d339f9969a4a8ef38f7029c95458af8a 249 Gene3D G3DSA:3.40.50.300 4 241 8.2E-85 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04660 47ee2d97c4c6ae81c69d85c84b0b955a 222 Gene3D G3DSA:3.40.50.300 5 150 1.4E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04660 47ee2d97c4c6ae81c69d85c84b0b955a 222 SUPERFAMILY SSF52540 5 212 5.51E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22915 47ee2d97c4c6ae81c69d85c84b0b955a 222 Gene3D G3DSA:3.40.50.300 5 150 1.4E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22915 47ee2d97c4c6ae81c69d85c84b0b955a 222 SUPERFAMILY SSF52540 5 212 5.51E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21875 47ee2d97c4c6ae81c69d85c84b0b955a 222 Gene3D G3DSA:3.40.50.300 5 150 1.4E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21875 47ee2d97c4c6ae81c69d85c84b0b955a 222 SUPERFAMILY SSF52540 5 212 5.51E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11865 47ee2d97c4c6ae81c69d85c84b0b955a 222 Gene3D G3DSA:3.40.50.300 5 150 1.4E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11865 47ee2d97c4c6ae81c69d85c84b0b955a 222 SUPERFAMILY SSF52540 5 212 5.51E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10260 47ee2d97c4c6ae81c69d85c84b0b955a 222 Gene3D G3DSA:3.40.50.300 5 150 1.4E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10260 47ee2d97c4c6ae81c69d85c84b0b955a 222 SUPERFAMILY SSF52540 5 212 5.51E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03910 47ee2d97c4c6ae81c69d85c84b0b955a 222 Gene3D G3DSA:3.40.50.300 5 150 1.4E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03910 47ee2d97c4c6ae81c69d85c84b0b955a 222 SUPERFAMILY SSF52540 5 212 5.51E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03150 47ee2d97c4c6ae81c69d85c84b0b955a 222 Gene3D G3DSA:3.40.50.300 5 150 1.4E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03150 47ee2d97c4c6ae81c69d85c84b0b955a 222 SUPERFAMILY SSF52540 5 212 5.51E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16950 47ee2d97c4c6ae81c69d85c84b0b955a 222 Gene3D G3DSA:3.40.50.300 5 150 1.4E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16950 47ee2d97c4c6ae81c69d85c84b0b955a 222 SUPERFAMILY SSF52540 5 212 5.51E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03590 47ee2d97c4c6ae81c69d85c84b0b955a 222 Gene3D G3DSA:3.40.50.300 5 150 1.4E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03590 47ee2d97c4c6ae81c69d85c84b0b955a 222 SUPERFAMILY SSF52540 5 212 5.51E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13190 726b03024cb6febca74517259d2a621c 309 Gene3D G3DSA:2.70.70.10 162 307 7.4E-49 T 22-04-2016 HRM2_RS13190 726b03024cb6febca74517259d2a621c 309 Pfam PF01551 Peptidase family M23 209 303 5.7E-32 T 22-04-2016 IPR016047 Peptidase M23 HRM2_RS13190 726b03024cb6febca74517259d2a621c 309 PANTHER PTHR21666 187 307 1.2E-45 T 22-04-2016 HRM2_RS13190 726b03024cb6febca74517259d2a621c 309 SUPERFAMILY SSF51261 178 307 4.45E-54 T 22-04-2016 IPR011055 Duplicated hybrid motif HRM2_RS05930 04b611a642cca2dce6e9a10a91d3a1aa 262 PIRSF PIRSF005902 1 259 1.5E-54 T 22-04-2016 IPR001130 TatD family GO:0016788 HRM2_RS05930 04b611a642cca2dce6e9a10a91d3a1aa 262 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 124 134 - T 22-04-2016 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 HRM2_RS05930 04b611a642cca2dce6e9a10a91d3a1aa 262 Gene3D G3DSA:3.20.20.140 2 256 1.1E-66 T 22-04-2016 HRM2_RS05930 04b611a642cca2dce6e9a10a91d3a1aa 262 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 189 205 - T 22-04-2016 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 HRM2_RS05930 04b611a642cca2dce6e9a10a91d3a1aa 262 SUPERFAMILY SSF51556 3 256 7.09E-66 T 22-04-2016 IPR032466 Metal-dependent hydrolase HRM2_RS05930 04b611a642cca2dce6e9a10a91d3a1aa 262 Pfam PF01026 TatD related DNase 4 255 6.6E-57 T 22-04-2016 IPR001130 TatD family GO:0016788 HRM2_RS05930 04b611a642cca2dce6e9a10a91d3a1aa 262 PANTHER PTHR10060 3 259 5.0E-78 T 22-04-2016 IPR001130 TatD family GO:0016788 HRM2_RS21275 0efcb11abd8915ae7f20d9bf282bf834 425 PANTHER PTHR30329:SF5 309 425 4.2E-24 T 22-04-2016 HRM2_RS21275 0efcb11abd8915ae7f20d9bf282bf834 425 Gene3D G3DSA:3.30.1330.60 294 422 2.2E-28 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS21275 0efcb11abd8915ae7f20d9bf282bf834 425 Pfam PF00691 OmpA family 310 416 1.5E-15 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS21275 0efcb11abd8915ae7f20d9bf282bf834 425 SUPERFAMILY SSF103088 298 422 7.06E-26 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS21275 0efcb11abd8915ae7f20d9bf282bf834 425 PANTHER PTHR30329 309 425 4.2E-24 T 22-04-2016 HRM2_RS12610 d06e2d987a7d19bdb2bbf464e318a10d 399 Pfam PF13439 Glycosyltransferase Family 4 14 219 1.7E-14 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain HRM2_RS12610 d06e2d987a7d19bdb2bbf464e318a10d 399 Gene3D G3DSA:3.40.50.2000 222 374 9.9E-25 T 22-04-2016 HRM2_RS12610 d06e2d987a7d19bdb2bbf464e318a10d 399 SUPERFAMILY SSF53756 1 398 1.57E-73 T 22-04-2016 HRM2_RS12610 d06e2d987a7d19bdb2bbf464e318a10d 399 PANTHER PTHR12526 1 159 3.3E-63 T 22-04-2016 HRM2_RS12610 d06e2d987a7d19bdb2bbf464e318a10d 399 PANTHER PTHR12526 177 399 3.3E-63 T 22-04-2016 HRM2_RS12610 d06e2d987a7d19bdb2bbf464e318a10d 399 Pfam PF00534 Glycosyl transferases group 1 229 375 1.0E-29 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 HRM2_RS22470 fdb620f00f990f2443aa0f808eae8c84 432 PANTHER PTHR21256 31 432 5.8E-193 T 22-04-2016 HRM2_RS22470 fdb620f00f990f2443aa0f808eae8c84 432 PIRSF PIRSF000099 6 432 1.7E-161 T 22-04-2016 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HRM2_RS22470 fdb620f00f990f2443aa0f808eae8c84 432 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 4 431 40.332 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HRM2_RS22470 fdb620f00f990f2443aa0f808eae8c84 432 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 33 430 1.3E-158 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HRM2_RS22470 fdb620f00f990f2443aa0f808eae8c84 432 Pfam PF00815 Histidinol dehydrogenase 29 430 1.6E-159 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HRM2_RS22470 fdb620f00f990f2443aa0f808eae8c84 432 SUPERFAMILY SSF53720 30 431 4.51E-76 T 22-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 HRM2_RS22470 fdb620f00f990f2443aa0f808eae8c84 432 Gene3D G3DSA:3.40.50.1980 29 243 1.8E-68 T 22-04-2016 HRM2_RS22470 fdb620f00f990f2443aa0f808eae8c84 432 PRINTS PR00083 Histidinol dehydrogenase signature 365 383 2.1E-85 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HRM2_RS22470 fdb620f00f990f2443aa0f808eae8c84 432 PRINTS PR00083 Histidinol dehydrogenase signature 139 165 2.1E-85 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HRM2_RS22470 fdb620f00f990f2443aa0f808eae8c84 432 PRINTS PR00083 Histidinol dehydrogenase signature 174 200 2.1E-85 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HRM2_RS22470 fdb620f00f990f2443aa0f808eae8c84 432 PRINTS PR00083 Histidinol dehydrogenase signature 33 57 2.1E-85 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HRM2_RS22470 fdb620f00f990f2443aa0f808eae8c84 432 PRINTS PR00083 Histidinol dehydrogenase signature 204 229 2.1E-85 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HRM2_RS22470 fdb620f00f990f2443aa0f808eae8c84 432 PRINTS PR00083 Histidinol dehydrogenase signature 255 274 2.1E-85 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HRM2_RS22470 fdb620f00f990f2443aa0f808eae8c84 432 PRINTS PR00083 Histidinol dehydrogenase signature 233 254 2.1E-85 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HRM2_RS22470 fdb620f00f990f2443aa0f808eae8c84 432 PRINTS PR00083 Histidinol dehydrogenase signature 324 349 2.1E-85 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HRM2_RS22470 fdb620f00f990f2443aa0f808eae8c84 432 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 233 265 - T 22-04-2016 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 Pfam PF02743 Cache domain 44 272 8.3E-20 T 22-04-2016 IPR033479 Double Cache domain 1 HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 PANTHER PTHR24423:SF458 49 988 4.6E-144 T 22-04-2016 HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 365 487 1.6E-25 T 22-04-2016 IPR000014 PAS domain HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 SMART SM00387 725 849 2.4E-24 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 SUPERFAMILY SSF55785 478 602 5.14E-12 T 22-04-2016 IPR000014 PAS domain HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 Gene3D G3DSA:3.40.50.2300 870 993 1.6E-33 T 22-04-2016 HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 SMART SM00448 869 982 1.3E-27 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 SMART SM00091 369 435 1.0E-9 T 22-04-2016 IPR000014 PAS domain HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 SMART SM00091 492 556 8.1 T 22-04-2016 IPR000014 PAS domain HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 SUPERFAMILY SSF47384 608 682 2.35E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 PANTHER PTHR24423 49 988 4.6E-144 T 22-04-2016 HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 Gene3D G3DSA:3.30.450.20 479 602 3.4E-11 T 22-04-2016 HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 727 846 1.3E-17 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 Gene3D G3DSA:3.30.450.20 158 279 2.4E-11 T 22-04-2016 HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 SUPERFAMILY SSF52172 870 987 1.71E-31 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 Pfam PF00512 His Kinase A (phospho-acceptor) domain 621 682 1.4E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 SMART SM00388 619 685 4.2E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 SUPERFAMILY SSF55785 356 478 1.92E-23 T 22-04-2016 IPR000014 PAS domain HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 SUPERFAMILY SSF55874 675 847 4.06E-32 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 Pfam PF00072 Response regulator receiver domain 871 982 6.4E-23 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 Gene3D G3DSA:3.30.450.20 356 478 7.1E-24 T 22-04-2016 HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 Gene3D G3DSA:1.10.287.130 614 670 4.7E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 Pfam PF13188 PAS domain 493 554 1.4E-4 T 22-04-2016 IPR000014 PAS domain HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 Gene3D G3DSA:3.30.565.10 671 847 5.2E-34 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 Gene3D G3DSA:3.30.450.20 45 127 8.1E-5 T 22-04-2016 HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 PRINTS PR00344 Bacterial sensor protein C-terminal signature 833 846 4.9E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 PRINTS PR00344 Bacterial sensor protein C-terminal signature 809 827 4.9E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 PRINTS PR00344 Bacterial sensor protein C-terminal signature 796 806 4.9E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 PRINTS PR00344 Bacterial sensor protein C-terminal signature 778 792 4.9E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25040 4c6af4397a5ff9969b53623f7f3647b4 995 Pfam PF13426 PAS domain 380 479 2.3E-8 T 22-04-2016 IPR000014 PAS domain HRM2_RS14205 a7aa43d0a1d3cd6b9dce128000dd966e 429 PANTHER PTHR11360 9 418 2.9E-61 T 22-04-2016 HRM2_RS14205 a7aa43d0a1d3cd6b9dce128000dd966e 429 Gene3D G3DSA:1.20.1250.20 245 422 1.7E-10 T 22-04-2016 HRM2_RS14205 a7aa43d0a1d3cd6b9dce128000dd966e 429 SUPERFAMILY SSF103473 59 422 1.18E-37 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS14205 a7aa43d0a1d3cd6b9dce128000dd966e 429 Pfam PF07690 Major Facilitator Superfamily 52 387 6.2E-23 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS14205 a7aa43d0a1d3cd6b9dce128000dd966e 429 PANTHER PTHR11360:SF135 9 418 2.9E-61 T 22-04-2016 HRM2_RS14205 a7aa43d0a1d3cd6b9dce128000dd966e 429 Gene3D G3DSA:1.20.1250.20 25 209 1.6E-17 T 22-04-2016 HRM2_RS17340 3549feffbe9a8f93239911e9bf46b81f 520 TIGRFAM TIGR00277 HDIG: HDIG domain 331 408 4.3E-23 T 22-04-2016 IPR006675 HDIG domain HRM2_RS17340 3549feffbe9a8f93239911e9bf46b81f 520 PANTHER PTHR12826 189 518 1.2E-134 T 22-04-2016 HRM2_RS17340 3549feffbe9a8f93239911e9bf46b81f 520 Gene3D G3DSA:1.10.3210.10 316 494 5.5E-41 T 22-04-2016 IPR006674 HD domain HRM2_RS17340 3549feffbe9a8f93239911e9bf46b81f 520 SMART SM00322 207 274 1.5E-5 T 22-04-2016 IPR004087 K Homology domain GO:0003676 HRM2_RS17340 3549feffbe9a8f93239911e9bf46b81f 520 Pfam PF00013 KH domain 213 266 8.9E-6 T 22-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 HRM2_RS17340 3549feffbe9a8f93239911e9bf46b81f 520 Hamap MF_00335 Ribonuclease Y [rny]. 4 519 24.566 T 22-04-2016 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 HRM2_RS17340 3549feffbe9a8f93239911e9bf46b81f 520 SUPERFAMILY SSF54791 207 303 5.52E-15 T 22-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 HRM2_RS17340 3549feffbe9a8f93239911e9bf46b81f 520 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 11 518 5.1E-217 T 22-04-2016 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 HRM2_RS17340 3549feffbe9a8f93239911e9bf46b81f 520 Gene3D G3DSA:3.30.1370.10 219 279 2.0E-5 T 22-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 HRM2_RS17340 3549feffbe9a8f93239911e9bf46b81f 520 SUPERFAMILY SSF109604 323 469 4.04E-30 T 22-04-2016 HRM2_RS17340 3549feffbe9a8f93239911e9bf46b81f 520 Pfam PF12072 Domain of unknown function (DUF3552) 5 203 2.2E-43 T 22-04-2016 IPR022711 Ribonuclease Y, N-terminal HRM2_RS17340 3549feffbe9a8f93239911e9bf46b81f 520 SMART SM00471 331 437 4.4E-10 T 22-04-2016 IPR003607 HD/PDEase domain HRM2_RS17340 3549feffbe9a8f93239911e9bf46b81f 520 Pfam PF01966 HD domain 335 426 5.3E-18 T 22-04-2016 IPR006674 HD domain HRM2_RS05060 47d8b2d65f52bc210b3dfd6d83475a28 863 Pfam PF00324 Amino acid permease 31 461 1.2E-54 T 22-04-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 HRM2_RS05060 47d8b2d65f52bc210b3dfd6d83475a28 863 Pfam PF03522 Solute carrier family 12 622 691 4.7E-10 T 22-04-2016 IPR018491 SLC12A transporter, C-terminal GO:0005215|GO:0006811|GO:0016020 Reactome: REACT_15518 HRM2_RS05060 47d8b2d65f52bc210b3dfd6d83475a28 863 PANTHER PTHR11827 24 691 5.1E-174 T 22-04-2016 HRM2_RS18545 1c0327fa18bde798025ee63f368376f3 73 Pfam PF13187 4Fe-4S dicluster domain 16 61 1.9E-7 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS18545 1c0327fa18bde798025ee63f368376f3 73 PANTHER PTHR24960:SF34 11 64 5.8E-12 T 22-04-2016 HRM2_RS18545 1c0327fa18bde798025ee63f368376f3 73 SUPERFAMILY SSF54862 4 67 2.37E-16 T 22-04-2016 HRM2_RS18545 1c0327fa18bde798025ee63f368376f3 73 Gene3D G3DSA:3.30.70.20 11 64 3.0E-13 T 22-04-2016 HRM2_RS18545 1c0327fa18bde798025ee63f368376f3 73 PANTHER PTHR24960 11 64 5.8E-12 T 22-04-2016 HRM2_RS18545 1c0327fa18bde798025ee63f368376f3 73 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 16 27 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS18545 1c0327fa18bde798025ee63f368376f3 73 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 47 58 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS23030 dec23fc4e0905b9b1eb3f14f24ba5165 681 PANTHER PTHR10953:SF145 23 164 1.1E-28 T 22-04-2016 HRM2_RS23030 dec23fc4e0905b9b1eb3f14f24ba5165 681 SUPERFAMILY SSF69572 18 273 9.81E-50 T 22-04-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 HRM2_RS23030 dec23fc4e0905b9b1eb3f14f24ba5165 681 SUPERFAMILY SSF55469 426 479 2.09E-5 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 HRM2_RS23030 dec23fc4e0905b9b1eb3f14f24ba5165 681 SUPERFAMILY SSF55469 554 613 2.09E-5 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 HRM2_RS23030 dec23fc4e0905b9b1eb3f14f24ba5165 681 Gene3D G3DSA:3.40.50.720 20 259 9.2E-37 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS23030 dec23fc4e0905b9b1eb3f14f24ba5165 681 Gene3D G3DSA:3.40.109.30 320 402 2.7E-11 T 22-04-2016 HRM2_RS23030 dec23fc4e0905b9b1eb3f14f24ba5165 681 Pfam PF00899 ThiF family 27 281 1.4E-40 T 22-04-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 HRM2_RS23030 dec23fc4e0905b9b1eb3f14f24ba5165 681 SUPERFAMILY SSF55469 319 398 2.22E-8 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 HRM2_RS23030 dec23fc4e0905b9b1eb3f14f24ba5165 681 PANTHER PTHR10953 23 164 1.1E-28 T 22-04-2016 HRM2_RS08180 fda1bf2cf6c60a787308f60530c8e4ed 590 Gene3D G3DSA:3.40.50.300 2 165 1.8E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08180 fda1bf2cf6c60a787308f60530c8e4ed 590 PANTHER PTHR11669 1 436 1.6E-153 T 22-04-2016 HRM2_RS08180 fda1bf2cf6c60a787308f60530c8e4ed 590 Pfam PF13177 DNA polymerase III, delta subunit 20 175 1.9E-41 T 22-04-2016 HRM2_RS08180 fda1bf2cf6c60a787308f60530c8e4ed 590 Gene3D G3DSA:1.10.8.60 166 229 3.6E-21 T 22-04-2016 HRM2_RS08180 fda1bf2cf6c60a787308f60530c8e4ed 590 SUPERFAMILY SSF48019 252 372 2.21E-17 T 22-04-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 HRM2_RS08180 fda1bf2cf6c60a787308f60530c8e4ed 590 SUPERFAMILY SSF52540 31 220 2.34E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08180 fda1bf2cf6c60a787308f60530c8e4ed 590 SMART SM00382 37 179 1.1E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS08180 fda1bf2cf6c60a787308f60530c8e4ed 590 PANTHER PTHR11669:SF0 1 436 1.6E-153 T 22-04-2016 HRM2_RS08180 fda1bf2cf6c60a787308f60530c8e4ed 590 Gene3D G3DSA:1.20.272.10 251 372 1.2E-20 T 22-04-2016 HRM2_RS08180 fda1bf2cf6c60a787308f60530c8e4ed 590 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 243 371 6.1E-19 T 22-04-2016 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 HRM2_RS08180 fda1bf2cf6c60a787308f60530c8e4ed 590 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 367 1.2E-127 T 22-04-2016 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 HRM2_RS15185 acc278bba74e48ad45780345c4b80198 511 SUPERFAMILY SSF51905 11 94 4.81E-7 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS15185 acc278bba74e48ad45780345c4b80198 511 Pfam PF02662 Methyl-viologen-reducing hydrogenase, delta subunit 393 511 3.0E-36 T 22-04-2016 IPR003813 Methyl-viologen-reducing hydrogenase, delta subunit GO:0015948|GO:0055114 HRM2_RS15185 acc278bba74e48ad45780345c4b80198 511 Gene3D G3DSA:3.30.70.20 309 378 1.8E-16 T 22-04-2016 HRM2_RS15185 acc278bba74e48ad45780345c4b80198 511 SUPERFAMILY SSF54862 288 374 7.75E-18 T 22-04-2016 HRM2_RS15185 acc278bba74e48ad45780345c4b80198 511 Gene3D G3DSA:3.50.50.60 14 52 1.6E-7 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS15185 acc278bba74e48ad45780345c4b80198 511 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 351 362 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS15185 acc278bba74e48ad45780345c4b80198 511 Pfam PF00037 4Fe-4S binding domain 346 367 5.5E-5 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS08795 cb6f40af2addef09e94c6e3c97e5a4f0 284 SUPERFAMILY SSF56436 34 283 2.83E-59 T 22-04-2016 IPR016187 C-type lectin fold HRM2_RS08795 cb6f40af2addef09e94c6e3c97e5a4f0 284 PANTHER PTHR23150 31 283 1.6E-42 T 22-04-2016 HRM2_RS08795 cb6f40af2addef09e94c6e3c97e5a4f0 284 Pfam PF03781 Sulfatase-modifying factor enzyme 1 37 282 3.9E-42 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme HRM2_RS08795 cb6f40af2addef09e94c6e3c97e5a4f0 284 PANTHER PTHR23150:SF19 31 283 1.6E-42 T 22-04-2016 HRM2_RS08795 cb6f40af2addef09e94c6e3c97e5a4f0 284 Gene3D G3DSA:3.90.1580.10 29 283 1.4E-60 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme HRM2_RS07330 f43dc72524ce653f9749acc461ff412f 503 SUPERFAMILY SSF53335 5 502 3.65E-121 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS07330 f43dc72524ce653f9749acc461ff412f 503 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 290 296 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HRM2_RS07330 f43dc72524ce653f9749acc461ff412f 503 Pfam PF02384 N-6 DNA Methylase 138 471 1.8E-61 T 22-04-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 HRM2_RS07330 f43dc72524ce653f9749acc461ff412f 503 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 287 299 3.52E-19 T 22-04-2016 HRM2_RS07330 f43dc72524ce653f9749acc461ff412f 503 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 158 174 3.52E-19 T 22-04-2016 HRM2_RS07330 f43dc72524ce653f9749acc461ff412f 503 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 317 341 3.52E-19 T 22-04-2016 HRM2_RS07330 f43dc72524ce653f9749acc461ff412f 503 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 182 196 3.52E-19 T 22-04-2016 HRM2_RS07330 f43dc72524ce653f9749acc461ff412f 503 PANTHER PTHR30195:SF12 1 502 2.5E-161 T 22-04-2016 HRM2_RS07330 f43dc72524ce653f9749acc461ff412f 503 Gene3D G3DSA:3.40.50.150 161 202 1.2E-42 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS07330 f43dc72524ce653f9749acc461ff412f 503 Gene3D G3DSA:3.40.50.150 235 420 1.2E-42 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS07330 f43dc72524ce653f9749acc461ff412f 503 PANTHER PTHR30195 1 502 2.5E-161 T 22-04-2016 HRM2_RS07330 f43dc72524ce653f9749acc461ff412f 503 Pfam PF12161 HsdM N-terminal domain 7 128 7.9E-13 T 22-04-2016 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain HRM2_RS00765 f44f1480dfe4bf74c0805b5ae0d02093 546 Gene3D G3DSA:2.40.40.20 371 528 1.0E-53 T 22-04-2016 HRM2_RS00765 f44f1480dfe4bf74c0805b5ae0d02093 546 Pfam PF00384 Molybdopterin oxidoreductase 10 332 2.5E-67 T 22-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 HRM2_RS00765 f44f1480dfe4bf74c0805b5ae0d02093 546 Pfam PF01568 Molydopterin dinucleotide binding domain 416 521 7.7E-32 T 22-04-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 HRM2_RS00765 f44f1480dfe4bf74c0805b5ae0d02093 546 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 279 296 - T 22-04-2016 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 HRM2_RS00765 f44f1480dfe4bf74c0805b5ae0d02093 546 Gene3D G3DSA:3.40.228.10 7 206 2.5E-68 T 22-04-2016 HRM2_RS00765 f44f1480dfe4bf74c0805b5ae0d02093 546 Gene3D G3DSA:3.40.50.740 224 355 2.2E-53 T 22-04-2016 HRM2_RS00765 f44f1480dfe4bf74c0805b5ae0d02093 546 SUPERFAMILY SSF53706 8 418 2.49E-141 T 22-04-2016 HRM2_RS00765 f44f1480dfe4bf74c0805b5ae0d02093 546 PANTHER PTHR11615 1 528 6.3E-147 T 22-04-2016 HRM2_RS00765 f44f1480dfe4bf74c0805b5ae0d02093 546 PANTHER PTHR11615:SF162 1 528 6.3E-147 T 22-04-2016 HRM2_RS00765 f44f1480dfe4bf74c0805b5ae0d02093 546 SUPERFAMILY SSF50692 372 528 1.95E-47 T 22-04-2016 IPR009010 Aspartate decarboxylase-like domain HRM2_RS11000 29b7b2491bfa74bfe9665dbcb8cb4885 231 PANTHER PTHR21600:SF24 2 229 3.4E-73 T 22-04-2016 HRM2_RS11000 29b7b2491bfa74bfe9665dbcb8cb4885 231 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 70 223 2.7E-46 T 22-04-2016 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 HRM2_RS11000 29b7b2491bfa74bfe9665dbcb8cb4885 231 SUPERFAMILY SSF55120 65 226 3.12E-38 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS11000 29b7b2491bfa74bfe9665dbcb8cb4885 231 Gene3D G3DSA:3.10.290.10 2 61 2.9E-21 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HRM2_RS11000 29b7b2491bfa74bfe9665dbcb8cb4885 231 SUPERFAMILY SSF55174 2 91 1.75E-13 T 22-04-2016 HRM2_RS11000 29b7b2491bfa74bfe9665dbcb8cb4885 231 Pfam PF01479 S4 domain 2 44 1.8E-9 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HRM2_RS11000 29b7b2491bfa74bfe9665dbcb8cb4885 231 Pfam PF00849 RNA pseudouridylate synthase 66 190 1.4E-14 T 22-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS11000 29b7b2491bfa74bfe9665dbcb8cb4885 231 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 101 115 - T 22-04-2016 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 HRM2_RS11000 29b7b2491bfa74bfe9665dbcb8cb4885 231 PANTHER PTHR21600 2 229 3.4E-73 T 22-04-2016 HRM2_RS11000 29b7b2491bfa74bfe9665dbcb8cb4885 231 SMART SM00363 2 62 4.1E-10 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HRM2_RS10870 e11fafb4c7d899393be203820bd2c509 1404 SUPERFAMILY SSF53067 5 253 2.07E-23 T 22-04-2016 HRM2_RS10870 e11fafb4c7d899393be203820bd2c509 1404 PANTHER PTHR32329:SF7 6 1241 2.5E-153 T 22-04-2016 HRM2_RS10870 e11fafb4c7d899393be203820bd2c509 1404 PANTHER PTHR32329 6 1241 2.5E-153 T 22-04-2016 HRM2_RS10870 e11fafb4c7d899393be203820bd2c509 1404 Gene3D G3DSA:3.30.420.40 424 561 1.0E-37 T 22-04-2016 HRM2_RS10870 e11fafb4c7d899393be203820bd2c509 1404 Gene3D G3DSA:3.30.420.40 95 233 7.5E-34 T 22-04-2016 HRM2_RS10870 e11fafb4c7d899393be203820bd2c509 1404 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 327 578 9.9E-41 T 22-04-2016 IPR008275 CoA enzyme activase HRM2_RS10870 e11fafb4c7d899393be203820bd2c509 1404 SUPERFAMILY SSF53067 326 578 7.5E-33 T 22-04-2016 HRM2_RS10870 e11fafb4c7d899393be203820bd2c509 1404 Gene3D G3DSA:3.30.420.40 326 403 2.6E-5 T 22-04-2016 HRM2_RS10870 e11fafb4c7d899393be203820bd2c509 1404 Pfam PF09989 CoA enzyme activase uncharacterised domain (DUF2229) 671 888 8.4E-39 T 22-04-2016 IPR018709 CoA enzyme activase, domain of unknown function DUF2229 HRM2_RS10870 e11fafb4c7d899393be203820bd2c509 1404 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 327 578 5.5E-36 T 22-04-2016 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type HRM2_RS10870 e11fafb4c7d899393be203820bd2c509 1404 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 7 252 1.1E-18 T 22-04-2016 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type HRM2_RS23615 93d87cbeeef9f53caa19ebc5b7ada97d 470 PANTHER PTHR11907:SF0 8 469 3.7E-218 T 22-04-2016 HRM2_RS23615 93d87cbeeef9f53caa19ebc5b7ada97d 470 PANTHER PTHR11907 8 469 3.7E-218 T 22-04-2016 HRM2_RS23615 93d87cbeeef9f53caa19ebc5b7ada97d 470 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 11 457 6.8E-157 T 22-04-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|UniPathway: UPA00074 HRM2_RS23615 93d87cbeeef9f53caa19ebc5b7ada97d 470 SUPERFAMILY SSF56235 11 255 5.32E-70 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal HRM2_RS23615 93d87cbeeef9f53caa19ebc5b7ada97d 470 SUPERFAMILY SSF53271 249 460 4.84E-65 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like HRM2_RS23615 93d87cbeeef9f53caa19ebc5b7ada97d 470 Gene3D G3DSA:3.60.20.10 11 256 5.6E-70 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal HRM2_RS23615 93d87cbeeef9f53caa19ebc5b7ada97d 470 Pfam PF13537 Glutamine amidotransferase domain 85 210 1.8E-18 T 22-04-2016 IPR017932 Glutamine amidotransferase type 2 domain HRM2_RS23615 93d87cbeeef9f53caa19ebc5b7ada97d 470 PIRSF PIRSF000485 7 468 4.2E-169 T 22-04-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|UniPathway: UPA00074 HRM2_RS23615 93d87cbeeef9f53caa19ebc5b7ada97d 470 Gene3D G3DSA:3.40.50.2020 269 437 2.2E-39 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like HRM2_RS23615 93d87cbeeef9f53caa19ebc5b7ada97d 470 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 10 458 46.209 T 22-04-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|UniPathway: UPA00074 HRM2_RS15395 0df82cc62bd54a9d889dd7642850e207 425 Gene3D G3DSA:3.40.50.620 200 412 4.2E-81 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS15395 0df82cc62bd54a9d889dd7642850e207 425 PANTHER PTHR11055:SF19 1 412 2.6E-158 T 22-04-2016 HRM2_RS15395 0df82cc62bd54a9d889dd7642850e207 425 PANTHER PTHR11055 1 412 2.6E-158 T 22-04-2016 HRM2_RS15395 0df82cc62bd54a9d889dd7642850e207 425 Gene3D G3DSA:3.10.400.10 5 199 1.4E-56 T 22-04-2016 HRM2_RS15395 0df82cc62bd54a9d889dd7642850e207 425 SUPERFAMILY SSF52374 188 405 2.81E-73 T 22-04-2016 HRM2_RS15395 0df82cc62bd54a9d889dd7642850e207 425 Pfam PF14306 PUA-like domain 6 178 4.6E-49 T 22-04-2016 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|UniPathway: UPA00140 HRM2_RS15395 0df82cc62bd54a9d889dd7642850e207 425 SUPERFAMILY SSF88697 4 183 1.99E-41 T 22-04-2016 IPR015947 PUA-like domain HRM2_RS15395 0df82cc62bd54a9d889dd7642850e207 425 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 7 403 3.9E-102 T 22-04-2016 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: REACT_13433|UniPathway: UPA00140 HRM2_RS15395 0df82cc62bd54a9d889dd7642850e207 425 Pfam PF01747 ATP-sulfurylase 189 404 4.5E-78 T 22-04-2016 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|UniPathway: UPA00140 HRM2_RS21660 9af1443165b407adf6c5aad73f47aa8a 272 SUPERFAMILY SSF159713 42 254 5.49E-43 T 22-04-2016 HRM2_RS21660 9af1443165b407adf6c5aad73f47aa8a 272 Pfam PF04016 Putative heavy-metal chelation 124 251 4.5E-28 T 22-04-2016 IPR007161 Putative heavy-metal chelation domain HRM2_RS03020 04d45547704fbee22618a29dc9a35d83 714 SUPERFAMILY SSF55424 576 692 9.28E-37 T 22-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 HRM2_RS03020 04d45547704fbee22618a29dc9a35d83 714 Pfam PF09335 SNARE associated Golgi protein 70 187 1.8E-25 T 22-04-2016 IPR032816 SNARE associated Golgi protein HRM2_RS03020 04d45547704fbee22618a29dc9a35d83 714 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 275 285 - T 22-04-2016 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 HRM2_RS03020 04d45547704fbee22618a29dc9a35d83 714 PANTHER PTHR22912:SF29 224 692 5.0E-158 T 22-04-2016 HRM2_RS03020 04d45547704fbee22618a29dc9a35d83 714 Gene3D G3DSA:3.50.50.60 239 374 8.5E-36 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS03020 04d45547704fbee22618a29dc9a35d83 714 SUPERFAMILY SSF51905 239 604 2.38E-59 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS03020 04d45547704fbee22618a29dc9a35d83 714 PANTHER PTHR22912 224 692 5.0E-158 T 22-04-2016 HRM2_RS03020 04d45547704fbee22618a29dc9a35d83 714 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 580 688 9.0E-29 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HRM2_RS03020 04d45547704fbee22618a29dc9a35d83 714 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 663 683 8.7E-58 T 22-04-2016 HRM2_RS03020 04d45547704fbee22618a29dc9a35d83 714 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 371 380 8.7E-58 T 22-04-2016 HRM2_RS03020 04d45547704fbee22618a29dc9a35d83 714 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 242 264 8.7E-58 T 22-04-2016 HRM2_RS03020 04d45547704fbee22618a29dc9a35d83 714 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 641 656 8.7E-58 T 22-04-2016 HRM2_RS03020 04d45547704fbee22618a29dc9a35d83 714 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 495 509 8.7E-58 T 22-04-2016 HRM2_RS03020 04d45547704fbee22618a29dc9a35d83 714 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 407 432 8.7E-58 T 22-04-2016 HRM2_RS03020 04d45547704fbee22618a29dc9a35d83 714 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 576 597 8.7E-58 T 22-04-2016 HRM2_RS03020 04d45547704fbee22618a29dc9a35d83 714 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 289 8.7E-58 T 22-04-2016 HRM2_RS03020 04d45547704fbee22618a29dc9a35d83 714 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 538 545 8.7E-58 T 22-04-2016 HRM2_RS03020 04d45547704fbee22618a29dc9a35d83 714 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 241 557 1.4E-60 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS03020 04d45547704fbee22618a29dc9a35d83 714 Gene3D G3DSA:3.50.50.60 375 565 6.7E-53 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS03020 04d45547704fbee22618a29dc9a35d83 714 Gene3D G3DSA:3.30.390.30 575 692 4.9E-39 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HRM2_RS03020 04d45547704fbee22618a29dc9a35d83 714 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 368 386 5.6E-29 T 22-04-2016 HRM2_RS03020 04d45547704fbee22618a29dc9a35d83 714 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 262 5.6E-29 T 22-04-2016 HRM2_RS03020 04d45547704fbee22618a29dc9a35d83 714 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 407 425 5.6E-29 T 22-04-2016 HRM2_RS03020 04d45547704fbee22618a29dc9a35d83 714 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 494 510 5.6E-29 T 22-04-2016 HRM2_RS03020 04d45547704fbee22618a29dc9a35d83 714 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 523 545 5.6E-29 T 22-04-2016 HRM2_RS04340 fb3120c034774736557988231d8a6f2b 631 SUPERFAMILY SSF100950 6 224 8.9E-38 T 22-04-2016 HRM2_RS04340 fb3120c034774736557988231d8a6f2b 631 SUPERFAMILY SSF55729 416 595 6.05E-13 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS04340 fb3120c034774736557988231d8a6f2b 631 PANTHER PTHR21432:SF18 9 436 3.8E-158 T 22-04-2016 HRM2_RS04340 fb3120c034774736557988231d8a6f2b 631 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 8 185 6.9E-27 T 22-04-2016 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 HRM2_RS04340 fb3120c034774736557988231d8a6f2b 631 Gene3D G3DSA:3.40.810.20 189 428 6.6E-39 T 22-04-2016 HRM2_RS04340 fb3120c034774736557988231d8a6f2b 631 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 273 426 1.6E-59 T 22-04-2016 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain HRM2_RS04340 fb3120c034774736557988231d8a6f2b 631 SUPERFAMILY SSF100950 187 435 1.29E-60 T 22-04-2016 HRM2_RS04340 fb3120c034774736557988231d8a6f2b 631 Gene3D G3DSA:3.40.1080.10 9 183 2.5E-53 T 22-04-2016 HRM2_RS04340 fb3120c034774736557988231d8a6f2b 631 Gene3D G3DSA:3.40.630.30 463 595 5.0E-12 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS04340 fb3120c034774736557988231d8a6f2b 631 Pfam PF00583 Acetyltransferase (GNAT) family 539 595 2.4E-4 T 22-04-2016 IPR000182 GNAT domain GO:0008080 HRM2_RS04340 fb3120c034774736557988231d8a6f2b 631 PANTHER PTHR21432 9 436 3.8E-158 T 22-04-2016 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 HRM2_RS06955 89429bb3fc4f147627de5f8f3e02f64b 439 PANTHER PTHR33362:SF7 9 439 7.6E-140 T 22-04-2016 HRM2_RS06955 89429bb3fc4f147627de5f8f3e02f64b 439 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 11 429 1.9E-88 T 22-04-2016 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit HRM2_RS06955 89429bb3fc4f147627de5f8f3e02f64b 439 PIRSF PIRSF006066 5 439 3.3E-74 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS06955 89429bb3fc4f147627de5f8f3e02f64b 439 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 21 434 1.6E-97 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS06955 89429bb3fc4f147627de5f8f3e02f64b 439 PANTHER PTHR33362 9 439 7.6E-140 T 22-04-2016 HRM2_RS02800 d4f40403fff4ddf37f76ce0df303795b 190 PANTHER PTHR30173 1 182 7.9E-47 T 22-04-2016 HRM2_RS02800 d4f40403fff4ddf37f76ce0df303795b 190 Pfam PF04542 Sigma-70 region 2 21 88 1.7E-16 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS02800 d4f40403fff4ddf37f76ce0df303795b 190 Gene3D G3DSA:1.10.10.10 119 184 1.2E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS02800 d4f40403fff4ddf37f76ce0df303795b 190 SUPERFAMILY SSF88946 2 93 8.63E-27 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS02800 d4f40403fff4ddf37f76ce0df303795b 190 Gene3D G3DSA:1.10.1740.10 1 99 2.1E-32 T 22-04-2016 HRM2_RS02800 d4f40403fff4ddf37f76ce0df303795b 190 SUPERFAMILY SSF88659 119 182 1.18E-15 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS02800 d4f40403fff4ddf37f76ce0df303795b 190 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 182 1.9E-32 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS02800 d4f40403fff4ddf37f76ce0df303795b 190 Pfam PF08281 Sigma-70, region 4 126 178 1.2E-16 T 22-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS16250 0ec90a103f4c333f165a08af6987de9f 358 PANTHER PTHR21716 8 341 1.2E-68 T 22-04-2016 IPR002549 Transmembrane protein TqsA-like HRM2_RS16250 0ec90a103f4c333f165a08af6987de9f 358 Pfam PF01594 Domain of unknown function DUF20 12 337 8.8E-49 T 22-04-2016 IPR002549 Transmembrane protein TqsA-like HRM2_RS16250 0ec90a103f4c333f165a08af6987de9f 358 PANTHER PTHR21716:SF13 8 341 1.2E-68 T 22-04-2016 HRM2_RS03995 d292ec4555884708c8f7867d44a5208b 599 Gene3D G3DSA:3.30.450.20 105 240 5.6E-21 T 22-04-2016 HRM2_RS03995 d292ec4555884708c8f7867d44a5208b 599 PANTHER PTHR21021:SF19 74 90 9.8E-53 T 22-04-2016 HRM2_RS03995 d292ec4555884708c8f7867d44a5208b 599 PANTHER PTHR21021:SF19 345 598 9.8E-53 T 22-04-2016 HRM2_RS03995 d292ec4555884708c8f7867d44a5208b 599 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 228 348 2.2E-26 T 22-04-2016 IPR000014 PAS domain HRM2_RS03995 d292ec4555884708c8f7867d44a5208b 599 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 135 227 1.8E-12 T 22-04-2016 IPR000014 PAS domain HRM2_RS03995 d292ec4555884708c8f7867d44a5208b 599 Gene3D G3DSA:3.30.450.20 241 343 8.6E-25 T 22-04-2016 HRM2_RS03995 d292ec4555884708c8f7867d44a5208b 599 Pfam PF00989 PAS fold 232 342 1.4E-16 T 22-04-2016 IPR013767 PAS fold GO:0006355 HRM2_RS03995 d292ec4555884708c8f7867d44a5208b 599 SUPERFAMILY SSF55785 217 343 1.19E-27 T 22-04-2016 IPR000014 PAS domain HRM2_RS03995 d292ec4555884708c8f7867d44a5208b 599 SMART SM00331 367 589 1.8E-35 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 HRM2_RS03995 d292ec4555884708c8f7867d44a5208b 599 PANTHER PTHR21021 74 90 9.8E-53 T 22-04-2016 HRM2_RS03995 d292ec4555884708c8f7867d44a5208b 599 PANTHER PTHR21021 345 598 9.8E-53 T 22-04-2016 HRM2_RS03995 d292ec4555884708c8f7867d44a5208b 599 SMART SM00086 303 345 2.0E-4 T 22-04-2016 IPR001610 PAC motif HRM2_RS03995 d292ec4555884708c8f7867d44a5208b 599 SMART SM00086 178 220 1.7E-6 T 22-04-2016 IPR001610 PAC motif HRM2_RS03995 d292ec4555884708c8f7867d44a5208b 599 SMART SM00091 102 171 45.0 T 22-04-2016 IPR000014 PAS domain HRM2_RS03995 d292ec4555884708c8f7867d44a5208b 599 SMART SM00091 232 298 3.8E-12 T 22-04-2016 IPR000014 PAS domain HRM2_RS03995 d292ec4555884708c8f7867d44a5208b 599 SUPERFAMILY SSF55785 133 222 5.48E-16 T 22-04-2016 IPR000014 PAS domain HRM2_RS03995 d292ec4555884708c8f7867d44a5208b 599 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 400 589 2.6E-43 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 HRM2_RS03995 d292ec4555884708c8f7867d44a5208b 599 Pfam PF08447 PAS fold 136 213 1.8E-17 T 22-04-2016 IPR013655 PAS fold-3 GO:0005515 HRM2_RS00485 f25f94d3591583fd36ce11ce63aa48f5 244 PANTHER PTHR24220:SF589 3 216 2.1E-76 T 22-04-2016 HRM2_RS00485 f25f94d3591583fd36ce11ce63aa48f5 244 PANTHER PTHR24220 3 216 2.1E-76 T 22-04-2016 HRM2_RS00485 f25f94d3591583fd36ce11ce63aa48f5 244 SUPERFAMILY SSF52540 1 216 1.5E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00485 f25f94d3591583fd36ce11ce63aa48f5 244 Gene3D G3DSA:3.40.50.300 1 204 1.9E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00485 f25f94d3591583fd36ce11ce63aa48f5 244 Pfam PF00005 ABC transporter 17 156 2.6E-29 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS00485 f25f94d3591583fd36ce11ce63aa48f5 244 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS00485 f25f94d3591583fd36ce11ce63aa48f5 244 SMART SM00382 26 217 7.6E-16 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS05475 ce7cc6ac273879ef2df4283946deb351 333 Gene3D G3DSA:1.10.287.70 5 91 1.0E-18 T 22-04-2016 HRM2_RS05475 ce7cc6ac273879ef2df4283946deb351 333 SUPERFAMILY SSF116726 238 326 2.88E-15 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS05475 ce7cc6ac273879ef2df4283946deb351 333 PANTHER PTHR16254:SF21 7 269 5.4E-81 T 22-04-2016 HRM2_RS05475 ce7cc6ac273879ef2df4283946deb351 333 Pfam PF02080 TrkA-C domain 261 326 1.9E-11 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS05475 ce7cc6ac273879ef2df4283946deb351 333 SUPERFAMILY SSF51735 106 248 4.4E-35 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS05475 ce7cc6ac273879ef2df4283946deb351 333 Pfam PF02254 TrkA-N domain 110 225 2.6E-29 T 22-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 HRM2_RS05475 ce7cc6ac273879ef2df4283946deb351 333 Pfam PF07885 Ion channel 14 86 4.3E-15 T 22-04-2016 IPR013099 Potassium channel domain HRM2_RS05475 ce7cc6ac273879ef2df4283946deb351 333 PANTHER PTHR16254 7 269 5.4E-81 T 22-04-2016 HRM2_RS05475 ce7cc6ac273879ef2df4283946deb351 333 Gene3D G3DSA:3.30.70.1450 257 327 7.7E-18 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS05475 ce7cc6ac273879ef2df4283946deb351 333 SUPERFAMILY SSF81324 5 128 1.57E-24 T 22-04-2016 HRM2_RS05475 ce7cc6ac273879ef2df4283946deb351 333 Gene3D G3DSA:3.40.50.720 103 240 1.6E-37 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS06280 780801377858a7376cc193cffd16de97 514 Pfam PF01225 Mur ligase family, catalytic domain 29 101 3.1E-13 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 HRM2_RS06280 780801377858a7376cc193cffd16de97 514 PANTHER PTHR23135 18 505 7.4E-180 T 22-04-2016 HRM2_RS06280 780801377858a7376cc193cffd16de97 514 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 504 33.974 T 22-04-2016 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 UniPathway: UPA00219 HRM2_RS06280 780801377858a7376cc193cffd16de97 514 Pfam PF02875 Mur ligase family, glutamate ligase domain 339 422 1.6E-21 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HRM2_RS06280 780801377858a7376cc193cffd16de97 514 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 28 504 2.2E-151 T 22-04-2016 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 UniPathway: UPA00219 HRM2_RS06280 780801377858a7376cc193cffd16de97 514 SUPERFAMILY SSF53623 104 338 1.83E-70 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HRM2_RS06280 780801377858a7376cc193cffd16de97 514 Pfam PF08245 Mur ligase middle domain 113 319 5.5E-49 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HRM2_RS06280 780801377858a7376cc193cffd16de97 514 SUPERFAMILY SSF63418 24 104 2.09E-24 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 HRM2_RS06280 780801377858a7376cc193cffd16de97 514 Gene3D G3DSA:3.90.190.20 343 498 2.8E-49 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HRM2_RS06280 780801377858a7376cc193cffd16de97 514 SUPERFAMILY SSF53244 339 506 1.07E-43 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HRM2_RS06280 780801377858a7376cc193cffd16de97 514 Gene3D G3DSA:3.40.1190.10 104 342 3.5E-77 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HRM2_RS06280 780801377858a7376cc193cffd16de97 514 Gene3D G3DSA:3.40.1390.10 22 103 3.6E-25 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 HRM2_RS06280 780801377858a7376cc193cffd16de97 514 PANTHER PTHR23135:SF4 18 505 7.4E-180 T 22-04-2016 HRM2_RS03445 e980d5e34895142b1effd3e3904fbe47 442 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 349 358 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS03445 e980d5e34895142b1effd3e3904fbe47 442 Pfam PF00158 Sigma-54 interaction domain 136 303 4.8E-66 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS03445 e980d5e34895142b1effd3e3904fbe47 442 Gene3D G3DSA:3.40.50.2300 3 122 1.8E-35 T 22-04-2016 HRM2_RS03445 e980d5e34895142b1effd3e3904fbe47 442 Pfam PF02954 Bacterial regulatory protein, Fis family 398 439 7.1E-13 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS03445 e980d5e34895142b1effd3e3904fbe47 442 SUPERFAMILY SSF52172 3 180 3.98E-42 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS03445 e980d5e34895142b1effd3e3904fbe47 442 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 160 173 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS03445 e980d5e34895142b1effd3e3904fbe47 442 SUPERFAMILY SSF46689 350 440 2.11E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS03445 e980d5e34895142b1effd3e3904fbe47 442 Gene3D G3DSA:1.10.8.60 309 382 1.3E-24 T 22-04-2016 HRM2_RS03445 e980d5e34895142b1effd3e3904fbe47 442 Gene3D G3DSA:1.10.10.60 389 440 1.2E-15 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS03445 e980d5e34895142b1effd3e3904fbe47 442 PANTHER PTHR32071 1 440 2.6E-184 T 22-04-2016 HRM2_RS03445 e980d5e34895142b1effd3e3904fbe47 442 SMART SM00382 156 299 1.0E-4 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS03445 e980d5e34895142b1effd3e3904fbe47 442 SMART SM00448 3 114 5.2E-31 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS03445 e980d5e34895142b1effd3e3904fbe47 442 Gene3D G3DSA:3.40.50.300 135 307 4.7E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03445 e980d5e34895142b1effd3e3904fbe47 442 SUPERFAMILY SSF52540 136 379 2.88E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03445 e980d5e34895142b1effd3e3904fbe47 442 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 405 422 1.6E-6 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS03445 e980d5e34895142b1effd3e3904fbe47 442 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 422 442 1.6E-6 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS03445 e980d5e34895142b1effd3e3904fbe47 442 Pfam PF00072 Response regulator receiver domain 5 115 9.9E-29 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS09055 a4379646853b20c0d1d36801ee0826f3 357 Pfam PF00534 Glycosyl transferases group 1 171 329 8.2E-24 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 HRM2_RS09055 a4379646853b20c0d1d36801ee0826f3 357 SUPERFAMILY SSF53756 2 350 1.48E-53 T 22-04-2016 HRM2_RS09055 a4379646853b20c0d1d36801ee0826f3 357 PANTHER PTHR12526 19 31 2.9E-39 T 22-04-2016 HRM2_RS09055 a4379646853b20c0d1d36801ee0826f3 357 PANTHER PTHR12526 65 350 2.9E-39 T 22-04-2016 HRM2_RS09055 a4379646853b20c0d1d36801ee0826f3 357 Gene3D G3DSA:3.40.50.2000 141 328 1.7E-16 T 22-04-2016 HRM2_RS16695 7233f8f1e84a5019db5edb57f618a0dd 224 Gene3D G3DSA:1.10.10.10 3 68 3.6E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS16695 7233f8f1e84a5019db5edb57f618a0dd 224 SMART SM00345 10 68 1.3E-13 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS16695 7233f8f1e84a5019db5edb57f618a0dd 224 Pfam PF07729 FCD domain 78 201 2.0E-23 T 22-04-2016 IPR011711 GntR, C-terminal HRM2_RS16695 7233f8f1e84a5019db5edb57f618a0dd 224 PANTHER PTHR11751:SF384 8 94 1.0E-20 T 22-04-2016 HRM2_RS16695 7233f8f1e84a5019db5edb57f618a0dd 224 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 66 1.5E-15 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS16695 7233f8f1e84a5019db5edb57f618a0dd 224 SMART SM00895 78 202 2.1E-15 T 22-04-2016 IPR011711 GntR, C-terminal HRM2_RS16695 7233f8f1e84a5019db5edb57f618a0dd 224 Gene3D G3DSA:1.20.120.530 71 213 5.2E-26 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS16695 7233f8f1e84a5019db5edb57f618a0dd 224 SUPERFAMILY SSF48008 74 210 5.49E-25 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS16695 7233f8f1e84a5019db5edb57f618a0dd 224 SUPERFAMILY SSF46785 2 92 6.96E-16 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS16695 7233f8f1e84a5019db5edb57f618a0dd 224 PANTHER PTHR11751 8 94 1.0E-20 T 22-04-2016 HRM2_RS14910 e31bbfb018bd44387ae7ec2bf438d313 887 SUPERFAMILY SSF48452 661 753 1.59E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS14910 e31bbfb018bd44387ae7ec2bf438d313 887 Gene3D G3DSA:1.25.40.10 823 879 6.1E-12 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS14910 e31bbfb018bd44387ae7ec2bf438d313 887 Gene3D G3DSA:1.25.40.10 660 753 6.1E-12 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS24445 a40235c6009d3477cbb7d691acac0f84 1167 PIRSF PIRSF000159 1 1167 0.0 T 22-04-2016 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 HRM2_RS24445 a40235c6009d3477cbb7d691acac0f84 1167 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 269 364 1.3E-12 T 22-04-2016 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II HRM2_RS24445 a40235c6009d3477cbb7d691acac0f84 1167 SUPERFAMILY SSF52518 785 1166 1.39E-126 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS24445 a40235c6009d3477cbb7d691acac0f84 1167 Gene3D G3DSA:3.40.50.970 3 258 7.7E-112 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS24445 a40235c6009d3477cbb7d691acac0f84 1167 Gene3D G3DSA:3.40.50.970 790 1167 2.6E-143 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS24445 a40235c6009d3477cbb7d691acac0f84 1167 Gene3D G3DSA:4.10.780.10 631 665 6.0E-12 T 22-04-2016 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 HRM2_RS24445 a40235c6009d3477cbb7d691acac0f84 1167 Gene3D G3DSA:3.40.50.920 259 413 2.7E-59 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HRM2_RS24445 a40235c6009d3477cbb7d691acac0f84 1167 Gene3D G3DSA:3.40.920.10 416 622 1.1E-84 T 22-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HRM2_RS24445 a40235c6009d3477cbb7d691acac0f84 1167 Pfam PF10371 Domain of unknown function 634 676 2.0E-16 T 22-04-2016 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 HRM2_RS24445 a40235c6009d3477cbb7d691acac0f84 1167 SUPERFAMILY SSF54862 663 830 1.81E-21 T 22-04-2016 HRM2_RS24445 a40235c6009d3477cbb7d691acac0f84 1167 PANTHER PTHR32154:SF0 3 1167 0.0 T 22-04-2016 HRM2_RS24445 a40235c6009d3477cbb7d691acac0f84 1167 TIGRFAM TIGR02176 pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase 5 1167 0.0 T 22-04-2016 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 HRM2_RS24445 a40235c6009d3477cbb7d691acac0f84 1167 SUPERFAMILY SSF52518 3 258 6.08E-78 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS24445 a40235c6009d3477cbb7d691acac0f84 1167 PANTHER PTHR32154 3 1167 0.0 T 22-04-2016 HRM2_RS24445 a40235c6009d3477cbb7d691acac0f84 1167 SUPERFAMILY SSF53323 416 664 1.24E-80 T 22-04-2016 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 HRM2_RS24445 a40235c6009d3477cbb7d691acac0f84 1167 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 743 754 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS24445 a40235c6009d3477cbb7d691acac0f84 1167 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 687 698 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS24445 a40235c6009d3477cbb7d691acac0f84 1167 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 425 606 8.6E-31 T 22-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HRM2_RS24445 a40235c6009d3477cbb7d691acac0f84 1167 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 16 247 5.0E-80 T 22-04-2016 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 HRM2_RS24445 a40235c6009d3477cbb7d691acac0f84 1167 SUPERFAMILY SSF52922 259 411 1.71E-46 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HRM2_RS24445 a40235c6009d3477cbb7d691acac0f84 1167 Pfam PF13484 4Fe-4S double cluster binding domain 686 755 3.3E-9 T 22-04-2016 HRM2_RS24445 a40235c6009d3477cbb7d691acac0f84 1167 Gene3D G3DSA:3.30.70.20 670 774 6.1E-21 T 22-04-2016 HRM2_RS24445 a40235c6009d3477cbb7d691acac0f84 1167 SMART SM00890 603 677 6.2E-16 T 22-04-2016 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 HRM2_RS24445 a40235c6009d3477cbb7d691acac0f84 1167 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 954 1066 4.8E-8 T 22-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HRM2_RS22790 275b6363375b007d78335097ed9f3546 179 Gene3D G3DSA:3.30.1330.20 23 101 7.7E-27 T 22-04-2016 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain HRM2_RS22790 275b6363375b007d78335097ed9f3546 179 PANTHER PTHR39418 10 172 6.3E-37 T 22-04-2016 HRM2_RS22790 275b6363375b007d78335097ed9f3546 179 SUPERFAMILY SSF143555 10 141 6.02E-40 T 22-04-2016 HRM2_RS22790 275b6363375b007d78335097ed9f3546 179 PANTHER PTHR39418:SF1 10 172 6.3E-37 T 22-04-2016 HRM2_RS22790 275b6363375b007d78335097ed9f3546 179 Pfam PF02663 FmdE, Molybdenum formylmethanofuran dehydrogenase operon 16 119 1.5E-30 T 22-04-2016 IPR003814 Formylmethanofuran dehydrogenase, subunit E domain HRM2_RS22790 275b6363375b007d78335097ed9f3546 179 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 142 177 1.8E-10 T 22-04-2016 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 HRM2_RS02000 4a5ba87b5f4ad729a13748fd8a88c6bf 1125 Gene3D G3DSA:3.40.1140.10 17 236 2.8E-25 T 22-04-2016 HRM2_RS02000 4a5ba87b5f4ad729a13748fd8a88c6bf 1125 Pfam PF13555 P-loop containing region of AAA domain 19 79 5.0E-24 T 22-04-2016 HRM2_RS02000 4a5ba87b5f4ad729a13748fd8a88c6bf 1125 SUPERFAMILY SSF52540 45 69 2.75E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02000 4a5ba87b5f4ad729a13748fd8a88c6bf 1125 SUPERFAMILY SSF52540 852 1080 2.75E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02000 4a5ba87b5f4ad729a13748fd8a88c6bf 1125 Pfam PF13558 Putative exonuclease SbcCD, C subunit 980 1070 2.2E-22 T 22-04-2016 HRM2_RS14535 f1bd5d5939339d4f89efce49a386bbad 195 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 32 175 1.3E-57 T 22-04-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 HRM2_RS14535 f1bd5d5939339d4f89efce49a386bbad 195 PANTHER PTHR23133 1 195 1.8E-80 T 22-04-2016 HRM2_RS14535 f1bd5d5939339d4f89efce49a386bbad 195 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 3 195 38.094 T 22-04-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 HRM2_RS14535 f1bd5d5939339d4f89efce49a386bbad 195 SUPERFAMILY SSF54211 88 180 1.1E-30 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS14535 f1bd5d5939339d4f89efce49a386bbad 195 SUPERFAMILY SSF54211 3 86 9.48E-31 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS14535 f1bd5d5939339d4f89efce49a386bbad 195 Gene3D G3DSA:3.30.230.40 2 89 4.8E-34 T 22-04-2016 HRM2_RS14535 f1bd5d5939339d4f89efce49a386bbad 195 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 157 169 - T 22-04-2016 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 HRM2_RS14535 f1bd5d5939339d4f89efce49a386bbad 195 PANTHER PTHR23133:SF2 1 195 1.8E-80 T 22-04-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 HRM2_RS14535 f1bd5d5939339d4f89efce49a386bbad 195 Gene3D G3DSA:3.30.230.40 91 195 9.4E-26 T 22-04-2016 HRM2_RS14535 f1bd5d5939339d4f89efce49a386bbad 195 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 62 75 - T 22-04-2016 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 HRM2_RS08405 279c802658bde43c27e660ff918df21e 689 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 201 280 1.1E-19 T 22-04-2016 IPR028261 Dihydroprymidine dehydrogenase domain II HRM2_RS08405 279c802658bde43c27e660ff918df21e 689 SUPERFAMILY SSF51971 293 527 8.83E-32 T 22-04-2016 HRM2_RS08405 279c802658bde43c27e660ff918df21e 689 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 482 498 9.2E-5 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HRM2_RS08405 279c802658bde43c27e660ff918df21e 689 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 585 604 9.2E-5 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HRM2_RS08405 279c802658bde43c27e660ff918df21e 689 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 296 318 9.2E-5 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HRM2_RS08405 279c802658bde43c27e660ff918df21e 689 SUPERFAMILY SSF46548 203 303 2.3E-20 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS08405 279c802658bde43c27e660ff918df21e 689 Gene3D G3DSA:1.10.1060.10 211 296 1.7E-27 T 22-04-2016 HRM2_RS08405 279c802658bde43c27e660ff918df21e 689 Gene3D G3DSA:1.10.1060.10 628 674 9.3E-5 T 22-04-2016 HRM2_RS08405 279c802658bde43c27e660ff918df21e 689 PANTHER PTHR11938:SF108 203 604 1.3E-42 T 22-04-2016 HRM2_RS08405 279c802658bde43c27e660ff918df21e 689 PANTHER PTHR11938 203 604 1.3E-42 T 22-04-2016 HRM2_RS08405 279c802658bde43c27e660ff918df21e 689 Pfam PF04060 Putative Fe-S cluster 41 72 1.8E-10 T 22-04-2016 IPR007202 4Fe-4S domain GO:0051536 HRM2_RS08405 279c802658bde43c27e660ff918df21e 689 Gene3D G3DSA:3.40.50.720 297 445 2.7E-23 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS08405 279c802658bde43c27e660ff918df21e 689 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 168 179 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS08405 279c802658bde43c27e660ff918df21e 689 Gene3D G3DSA:3.50.50.60 446 542 6.5E-6 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS08405 279c802658bde43c27e660ff918df21e 689 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 3 94 8.2E-20 T 22-04-2016 IPR010207 Electron transport complex, RnfB/RsxB GO:0009055|GO:0051536 HRM2_RS08405 279c802658bde43c27e660ff918df21e 689 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 295 535 1.4E-9 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS08405 279c802658bde43c27e660ff918df21e 689 SUPERFAMILY SSF54862 138 219 1.4E-13 T 22-04-2016 HRM2_RS08405 279c802658bde43c27e660ff918df21e 689 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 432 450 1.8E-5 T 22-04-2016 HRM2_RS08405 279c802658bde43c27e660ff918df21e 689 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 519 535 1.8E-5 T 22-04-2016 HRM2_RS08405 279c802658bde43c27e660ff918df21e 689 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 297 316 1.8E-5 T 22-04-2016 HRM2_RS08405 279c802658bde43c27e660ff918df21e 689 Pfam PF00037 4Fe-4S binding domain 161 183 2.5E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS08405 279c802658bde43c27e660ff918df21e 689 Gene3D G3DSA:3.30.70.20 176 210 1.4E-8 T 22-04-2016 HRM2_RS08405 279c802658bde43c27e660ff918df21e 689 Gene3D G3DSA:3.30.70.20 131 175 6.4E-13 T 22-04-2016 HRM2_RS23460 dafac37c90789038ecb102b197d44f8b 390 PANTHER PTHR30469 6 387 1.1E-71 T 22-04-2016 HRM2_RS23460 dafac37c90789038ecb102b197d44f8b 390 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 59 308 1.5E-22 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain HRM2_RS23460 dafac37c90789038ecb102b197d44f8b 390 Gene3D G3DSA:2.40.50.100 202 233 5.5E-15 T 22-04-2016 HRM2_RS23460 dafac37c90789038ecb102b197d44f8b 390 Gene3D G3DSA:2.40.50.100 68 99 5.5E-15 T 22-04-2016 HRM2_RS23460 dafac37c90789038ecb102b197d44f8b 390 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 172 387 9.5E-38 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 HRM2_RS23460 dafac37c90789038ecb102b197d44f8b 390 PANTHER PTHR30469:SF15 6 387 1.1E-71 T 22-04-2016 HRM2_RS23460 dafac37c90789038ecb102b197d44f8b 390 SUPERFAMILY SSF111369 55 315 7.85E-20 T 22-04-2016 HRM2_RS03255 6d38a60b793a6858d1e3b9d4fa19c685 857 Gene3D G3DSA:3.80.30.20 262 493 1.3E-40 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe HRM2_RS03255 6d38a60b793a6858d1e3b9d4fa19c685 857 Pfam PF04055 Radical SAM superfamily 268 431 4.7E-15 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS03255 6d38a60b793a6858d1e3b9d4fa19c685 857 PANTHER PTHR11918:SF77 227 611 3.7E-196 T 22-04-2016 HRM2_RS03255 6d38a60b793a6858d1e3b9d4fa19c685 857 PANTHER PTHR11918:SF77 83 192 3.7E-196 T 22-04-2016 HRM2_RS03255 6d38a60b793a6858d1e3b9d4fa19c685 857 SUPERFAMILY SSF102114 236 600 2.75E-48 T 22-04-2016 HRM2_RS03255 6d38a60b793a6858d1e3b9d4fa19c685 857 PANTHER PTHR11918 227 611 3.7E-196 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein HRM2_RS03255 6d38a60b793a6858d1e3b9d4fa19c685 857 PANTHER PTHR11918 83 192 3.7E-196 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein HRM2_RS03255 6d38a60b793a6858d1e3b9d4fa19c685 857 Pfam PF10105 Uncharacterized protein conserved in bacteria (DUF2344) 648 827 7.1E-41 T 22-04-2016 IPR018768 Domain of unknown function DUF2344 HRM2_RS03255 6d38a60b793a6858d1e3b9d4fa19c685 857 SMART SM00729 263 489 1.2E-28 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS03255 6d38a60b793a6858d1e3b9d4fa19c685 857 TIGRFAM TIGR03936 sam_1_link_chp: radical SAM-linked protein 648 851 3.2E-53 T 22-04-2016 IPR018768 Domain of unknown function DUF2344 HRM2_RS03255 6d38a60b793a6858d1e3b9d4fa19c685 857 TIGRFAM TIGR03960 rSAM_fuse_unch: radical SAM family uncharacterized protein 8 614 4.6E-220 T 22-04-2016 IPR023862 Conserved hypothetical protein CHP03960, radical SAM HRM2_RS20385 f08d20286ef362fdde48df682a6defc0 343 PANTHER PTHR10846:SF8 33 339 1.9E-17 T 22-04-2016 HRM2_RS20385 f08d20286ef362fdde48df682a6defc0 343 Pfam PF01699 Sodium/calcium exchanger protein 17 167 5.3E-23 T 22-04-2016 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: REACT_15518 HRM2_RS20385 f08d20286ef362fdde48df682a6defc0 343 Pfam PF01699 Sodium/calcium exchanger protein 198 338 2.5E-21 T 22-04-2016 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: REACT_15518 HRM2_RS20385 f08d20286ef362fdde48df682a6defc0 343 PANTHER PTHR10846 33 339 1.9E-17 T 22-04-2016 IPR004481 Sodium/potassium/calcium exchanger Reactome: REACT_15518 HRM2_RS09505 4a463e82c16927f63ea8156a65436eb6 197 Pfam PF00589 Phage integrase family 26 182 7.2E-15 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS09505 4a463e82c16927f63ea8156a65436eb6 197 PANTHER PTHR30349:SF34 36 194 3.1E-23 T 22-04-2016 HRM2_RS09505 4a463e82c16927f63ea8156a65436eb6 197 PANTHER PTHR30349 36 194 3.1E-23 T 22-04-2016 HRM2_RS09505 4a463e82c16927f63ea8156a65436eb6 197 Gene3D G3DSA:1.10.443.10 24 190 1.6E-26 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS09505 4a463e82c16927f63ea8156a65436eb6 197 SUPERFAMILY SSF56349 21 190 1.03E-28 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HRM2_RS05575 e839a36971bc3a62c9b6d7def4b3e0a2 136 Pfam PF01809 Haemolytic domain 54 103 4.7E-16 T 22-04-2016 IPR002696 Putative membrane protein insertion efficiency factor HRM2_RS05575 e839a36971bc3a62c9b6d7def4b3e0a2 136 PANTHER PTHR33383 56 102 7.1E-15 T 22-04-2016 HRM2_RS05575 e839a36971bc3a62c9b6d7def4b3e0a2 136 SMART SM01234 54 107 4.6E-7 T 22-04-2016 IPR002696 Putative membrane protein insertion efficiency factor HRM2_RS05575 e839a36971bc3a62c9b6d7def4b3e0a2 136 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 61 102 4.0E-7 T 22-04-2016 IPR002696 Putative membrane protein insertion efficiency factor HRM2_RS20620 78902720862193011288e8592e17fcfe 455 SMART SM00448 5 116 4.4E-35 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS20620 78902720862193011288e8592e17fcfe 455 Pfam PF00158 Sigma-54 interaction domain 145 311 3.9E-67 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS20620 78902720862193011288e8592e17fcfe 455 Pfam PF00072 Response regulator receiver domain 7 114 2.8E-27 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS20620 78902720862193011288e8592e17fcfe 455 Gene3D G3DSA:3.40.50.300 142 317 1.8E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20620 78902720862193011288e8592e17fcfe 455 PANTHER PTHR32071:SF18 4 453 7.3E-196 T 22-04-2016 HRM2_RS20620 78902720862193011288e8592e17fcfe 455 PANTHER PTHR32071 4 453 7.3E-196 T 22-04-2016 HRM2_RS20620 78902720862193011288e8592e17fcfe 455 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 358 367 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS20620 78902720862193011288e8592e17fcfe 455 Gene3D G3DSA:1.10.10.60 401 453 6.5E-15 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS20620 78902720862193011288e8592e17fcfe 455 Pfam PF02954 Bacterial regulatory protein, Fis family 412 450 1.3E-11 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS20620 78902720862193011288e8592e17fcfe 455 SUPERFAMILY SSF46689 358 453 3.94E-15 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS20620 78902720862193011288e8592e17fcfe 455 Gene3D G3DSA:1.10.8.60 319 387 2.3E-23 T 22-04-2016 HRM2_RS20620 78902720862193011288e8592e17fcfe 455 SUPERFAMILY SSF52540 144 387 3.1E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20620 78902720862193011288e8592e17fcfe 455 Gene3D G3DSA:3.40.50.2300 6 128 8.9E-37 T 22-04-2016 HRM2_RS20620 78902720862193011288e8592e17fcfe 455 SUPERFAMILY SSF52172 6 190 2.28E-45 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS20620 78902720862193011288e8592e17fcfe 455 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 169 182 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS20620 78902720862193011288e8592e17fcfe 455 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 435 455 4.1E-8 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS20620 78902720862193011288e8592e17fcfe 455 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 418 435 4.1E-8 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS20620 78902720862193011288e8592e17fcfe 455 SMART SM00382 165 308 1.3E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS04210 5a9515f9cfb72c38a6cac3062b6c32ab 525 Pfam PF00512 His Kinase A (phospho-acceptor) domain 299 360 4.2E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS04210 5a9515f9cfb72c38a6cac3062b6c32ab 525 Gene3D G3DSA:1.10.287.130 293 358 9.6E-4 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS04210 5a9515f9cfb72c38a6cac3062b6c32ab 525 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 158 279 1.4E-5 T 22-04-2016 IPR000014 PAS domain HRM2_RS04210 5a9515f9cfb72c38a6cac3062b6c32ab 525 SUPERFAMILY SSF55785 163 276 7.91E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS04210 5a9515f9cfb72c38a6cac3062b6c32ab 525 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 402 515 4.1E-20 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS04210 5a9515f9cfb72c38a6cac3062b6c32ab 525 SUPERFAMILY SSF52172 20 187 1.01E-30 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS04210 5a9515f9cfb72c38a6cac3062b6c32ab 525 PANTHER PTHR24423 158 517 5.9E-61 T 22-04-2016 HRM2_RS04210 5a9515f9cfb72c38a6cac3062b6c32ab 525 Pfam PF13426 PAS domain 175 274 1.5E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS04210 5a9515f9cfb72c38a6cac3062b6c32ab 525 SMART SM00388 297 362 1.7E-4 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS04210 5a9515f9cfb72c38a6cac3062b6c32ab 525 SUPERFAMILY SSF47384 290 360 4.71E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS04210 5a9515f9cfb72c38a6cac3062b6c32ab 525 Pfam PF00072 Response regulator receiver domain 23 132 3.7E-23 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS04210 5a9515f9cfb72c38a6cac3062b6c32ab 525 Gene3D G3DSA:3.40.50.2300 20 152 1.6E-32 T 22-04-2016 HRM2_RS04210 5a9515f9cfb72c38a6cac3062b6c32ab 525 Gene3D G3DSA:3.30.565.10 373 517 1.1E-32 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS04210 5a9515f9cfb72c38a6cac3062b6c32ab 525 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 471 8.0E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS04210 5a9515f9cfb72c38a6cac3062b6c32ab 525 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 457 8.0E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS04210 5a9515f9cfb72c38a6cac3062b6c32ab 525 PRINTS PR00344 Bacterial sensor protein C-terminal signature 476 494 8.0E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS04210 5a9515f9cfb72c38a6cac3062b6c32ab 525 PRINTS PR00344 Bacterial sensor protein C-terminal signature 500 513 8.0E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS04210 5a9515f9cfb72c38a6cac3062b6c32ab 525 SMART SM00387 401 516 1.9E-26 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS04210 5a9515f9cfb72c38a6cac3062b6c32ab 525 Gene3D G3DSA:3.30.450.20 155 273 1.2E-7 T 22-04-2016 HRM2_RS04210 5a9515f9cfb72c38a6cac3062b6c32ab 525 SMART SM00448 20 133 3.0E-23 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS04210 5a9515f9cfb72c38a6cac3062b6c32ab 525 SUPERFAMILY SSF55874 386 515 1.1E-32 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS05465 c8760f7afedec4d1e8543d6f28d863fb 427 Gene3D G3DSA:3.30.930.10 105 420 1.6E-143 T 22-04-2016 HRM2_RS05465 c8760f7afedec4d1e8543d6f28d863fb 427 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 6.2E-27 T 22-04-2016 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|UniPathway: UPA00906 HRM2_RS05465 c8760f7afedec4d1e8543d6f28d863fb 427 PANTHER PTHR11778:SF0 1 427 5.3E-214 T 22-04-2016 HRM2_RS05465 c8760f7afedec4d1e8543d6f28d863fb 427 PIRSF PIRSF001529 1 425 4.3E-181 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 HRM2_RS05465 c8760f7afedec4d1e8543d6f28d863fb 427 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 221 398 1.7E-41 T 22-04-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS05465 c8760f7afedec4d1e8543d6f28d863fb 427 PRINTS PR00981 Seryl-tRNA synthetase signature 275 288 4.9E-33 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 HRM2_RS05465 c8760f7afedec4d1e8543d6f28d863fb 427 PRINTS PR00981 Seryl-tRNA synthetase signature 315 328 4.9E-33 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 HRM2_RS05465 c8760f7afedec4d1e8543d6f28d863fb 427 PRINTS PR00981 Seryl-tRNA synthetase signature 332 348 4.9E-33 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 HRM2_RS05465 c8760f7afedec4d1e8543d6f28d863fb 427 PRINTS PR00981 Seryl-tRNA synthetase signature 263 275 4.9E-33 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 HRM2_RS05465 c8760f7afedec4d1e8543d6f28d863fb 427 PRINTS PR00981 Seryl-tRNA synthetase signature 350 366 4.9E-33 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 HRM2_RS05465 c8760f7afedec4d1e8543d6f28d863fb 427 SUPERFAMILY SSF46589 1 112 5.75E-27 T 22-04-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 HRM2_RS05465 c8760f7afedec4d1e8543d6f28d863fb 427 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 421 41.952 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 HRM2_RS05465 c8760f7afedec4d1e8543d6f28d863fb 427 Gene3D G3DSA:1.10.287.40 1 104 3.6E-22 T 22-04-2016 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|UniPathway: UPA00906 HRM2_RS05465 c8760f7afedec4d1e8543d6f28d863fb 427 SUPERFAMILY SSF55681 117 417 2.94E-103 T 22-04-2016 HRM2_RS05465 c8760f7afedec4d1e8543d6f28d863fb 427 PANTHER PTHR11778 1 427 5.3E-214 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 HRM2_RS05465 c8760f7afedec4d1e8543d6f28d863fb 427 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 416 1.5E-171 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 HRM2_RS09245 2462e15c8e1494a65209c9de9d5ef3d5 940 Gene3D G3DSA:3.30.1490.20 133 155 3.9E-24 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HRM2_RS09245 2462e15c8e1494a65209c9de9d5ef3d5 940 Gene3D G3DSA:3.30.1490.20 202 249 3.9E-24 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HRM2_RS09245 2462e15c8e1494a65209c9de9d5ef3d5 940 Hamap MF_00205 UvrABC system protein A [uvrA]. 3 938 22.057 T 22-04-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 HRM2_RS09245 2462e15c8e1494a65209c9de9d5ef3d5 940 Gene3D G3DSA:1.20.1580.10 93 131 1.1E-52 T 22-04-2016 HRM2_RS09245 2462e15c8e1494a65209c9de9d5ef3d5 940 Gene3D G3DSA:1.20.1580.10 251 284 1.1E-52 T 22-04-2016 HRM2_RS09245 2462e15c8e1494a65209c9de9d5ef3d5 940 Gene3D G3DSA:1.20.1580.10 407 477 1.1E-52 T 22-04-2016 HRM2_RS09245 2462e15c8e1494a65209c9de9d5ef3d5 940 SUPERFAMILY SSF52540 610 908 1.16E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09245 2462e15c8e1494a65209c9de9d5ef3d5 940 SUPERFAMILY SSF52540 10 206 7.5E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09245 2462e15c8e1494a65209c9de9d5ef3d5 940 SUPERFAMILY SSF52540 430 569 7.5E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09245 2462e15c8e1494a65209c9de9d5ef3d5 940 Gene3D G3DSA:3.40.50.300 610 667 1.2E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09245 2462e15c8e1494a65209c9de9d5ef3d5 940 Gene3D G3DSA:3.40.50.300 478 597 6.1E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09245 2462e15c8e1494a65209c9de9d5ef3d5 940 Gene3D G3DSA:3.40.50.300 819 937 1.2E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09245 2462e15c8e1494a65209c9de9d5ef3d5 940 Gene3D G3DSA:3.40.50.300 4 91 6.1E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09245 2462e15c8e1494a65209c9de9d5ef3d5 940 Pfam PF00005 ABC transporter 805 858 1.7E-5 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS09245 2462e15c8e1494a65209c9de9d5ef3d5 940 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 923 0.0 T 22-04-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 HRM2_RS09245 2462e15c8e1494a65209c9de9d5ef3d5 940 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS09245 2462e15c8e1494a65209c9de9d5ef3d5 940 ProSitePatterns PS00211 ABC transporters family signature. 828 842 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS09245 2462e15c8e1494a65209c9de9d5ef3d5 940 Gene3D G3DSA:1.20.1580.10 692 818 2.4E-53 T 22-04-2016 HRM2_RS09245 2462e15c8e1494a65209c9de9d5ef3d5 940 PANTHER PTHR32282 2 940 0.0 T 22-04-2016 HRM2_RS09245 2462e15c8e1494a65209c9de9d5ef3d5 940 Gene3D G3DSA:1.10.8.280 286 406 6.9E-36 T 22-04-2016 HRM2_RS09245 2462e15c8e1494a65209c9de9d5ef3d5 940 PANTHER PTHR32282:SF2 2 940 0.0 T 22-04-2016 HRM2_RS08110 3daaae05dd893b3e5ce846f602d7f479 223 PANTHER PTHR16254 6 162 2.3E-44 T 22-04-2016 HRM2_RS08110 3daaae05dd893b3e5ce846f602d7f479 223 Gene3D G3DSA:3.40.50.720 3 142 2.3E-35 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS08110 3daaae05dd893b3e5ce846f602d7f479 223 Pfam PF02080 TrkA-C domain 159 221 5.9E-11 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS08110 3daaae05dd893b3e5ce846f602d7f479 223 Pfam PF02254 TrkA-N domain 8 123 7.7E-26 T 22-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 HRM2_RS08110 3daaae05dd893b3e5ce846f602d7f479 223 SUPERFAMILY SSF116726 134 220 1.03E-15 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS08110 3daaae05dd893b3e5ce846f602d7f479 223 Gene3D G3DSA:3.30.70.1450 155 222 1.1E-13 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS08110 3daaae05dd893b3e5ce846f602d7f479 223 SUPERFAMILY SSF51735 6 139 1.38E-31 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS21450 fc6a7ecde6f9d626ae07c9a9bd24947c 469 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 465 4.3E-225 T 22-04-2016 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS21450 fc6a7ecde6f9d626ae07c9a9bd24947c 469 ProSitePatterns PS00450 Aconitase family signature 1. 340 356 - T 22-04-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS21450 fc6a7ecde6f9d626ae07c9a9bd24947c 469 Gene3D G3DSA:3.30.499.10 296 466 4.1E-62 T 22-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS21450 fc6a7ecde6f9d626ae07c9a9bd24947c 469 SUPERFAMILY SSF53732 1 466 6.54E-164 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS21450 fc6a7ecde6f9d626ae07c9a9bd24947c 469 Pfam PF00330 Aconitase family (aconitate hydratase) 7 458 5.3E-153 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS21450 fc6a7ecde6f9d626ae07c9a9bd24947c 469 Gene3D G3DSA:3.30.499.10 2 154 2.7E-25 T 22-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS21450 fc6a7ecde6f9d626ae07c9a9bd24947c 469 PRINTS PR00415 Aconitase family signature 133 148 2.7E-47 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS21450 fc6a7ecde6f9d626ae07c9a9bd24947c 469 PRINTS PR00415 Aconitase family signature 195 208 2.7E-47 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS21450 fc6a7ecde6f9d626ae07c9a9bd24947c 469 PRINTS PR00415 Aconitase family signature 108 116 2.7E-47 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS21450 fc6a7ecde6f9d626ae07c9a9bd24947c 469 PRINTS PR00415 Aconitase family signature 344 355 2.7E-47 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS21450 fc6a7ecde6f9d626ae07c9a9bd24947c 469 PRINTS PR00415 Aconitase family signature 119 132 2.7E-47 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS21450 fc6a7ecde6f9d626ae07c9a9bd24947c 469 PRINTS PR00415 Aconitase family signature 400 413 2.7E-47 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS21450 fc6a7ecde6f9d626ae07c9a9bd24947c 469 PRINTS PR00415 Aconitase family signature 288 302 2.7E-47 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS21450 fc6a7ecde6f9d626ae07c9a9bd24947c 469 PRINTS PR00415 Aconitase family signature 82 95 2.7E-47 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS21450 fc6a7ecde6f9d626ae07c9a9bd24947c 469 PRINTS PR00415 Aconitase family signature 209 222 2.7E-47 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS21450 fc6a7ecde6f9d626ae07c9a9bd24947c 469 ProSitePatterns PS01244 Aconitase family signature 2. 400 413 - T 22-04-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS21450 fc6a7ecde6f9d626ae07c9a9bd24947c 469 PANTHER PTHR11670:SF38 328 466 2.1E-265 T 22-04-2016 HRM2_RS21450 fc6a7ecde6f9d626ae07c9a9bd24947c 469 PANTHER PTHR11670:SF38 1 309 2.1E-265 T 22-04-2016 HRM2_RS21450 fc6a7ecde6f9d626ae07c9a9bd24947c 469 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 467 57.396 T 22-04-2016 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS21450 fc6a7ecde6f9d626ae07c9a9bd24947c 469 Gene3D G3DSA:3.40.1060.10 155 291 3.2E-36 T 22-04-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS21450 fc6a7ecde6f9d626ae07c9a9bd24947c 469 PANTHER PTHR11670 328 466 2.1E-265 T 22-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS21450 fc6a7ecde6f9d626ae07c9a9bd24947c 469 PANTHER PTHR11670 1 309 2.1E-265 T 22-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS02205 447d71e7057521350bf65dc313959f6c 66 Gene3D G3DSA:2.40.50.140 3 64 5.0E-29 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS02205 447d71e7057521350bf65dc313959f6c 66 PANTHER PTHR11544 2 65 1.4E-28 T 22-04-2016 HRM2_RS02205 447d71e7057521350bf65dc313959f6c 66 PIRSF PIRSF002599 1 66 2.3E-21 T 22-04-2016 IPR012156 Cold shock, CspA GO:0003676 HRM2_RS02205 447d71e7057521350bf65dc313959f6c 66 SMART SM00357 3 66 1.3E-25 T 22-04-2016 IPR011129 Cold shock protein GO:0003676 HRM2_RS02205 447d71e7057521350bf65dc313959f6c 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 5.1E-28 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HRM2_RS02205 447d71e7057521350bf65dc313959f6c 66 PRINTS PR00050 Cold shock protein signature 24 33 8.0E-17 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HRM2_RS02205 447d71e7057521350bf65dc313959f6c 66 PRINTS PR00050 Cold shock protein signature 39 57 8.0E-17 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HRM2_RS02205 447d71e7057521350bf65dc313959f6c 66 PRINTS PR00050 Cold shock protein signature 4 19 8.0E-17 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HRM2_RS02205 447d71e7057521350bf65dc313959f6c 66 SUPERFAMILY SSF50249 2 64 3.64E-22 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS02205 447d71e7057521350bf65dc313959f6c 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 22-04-2016 IPR019844 Cold-shock conserved site HRM2_RS15760 46bd94c91de23a1f15cc6e279133a63d 497 Gene3D G3DSA:1.10.10.60 412 487 2.3E-6 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS15760 46bd94c91de23a1f15cc6e279133a63d 497 Gene3D G3DSA:1.10.8.60 363 411 5.3E-8 T 22-04-2016 HRM2_RS15760 46bd94c91de23a1f15cc6e279133a63d 497 SUPERFAMILY SSF52540 157 422 3.51E-39 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS15760 46bd94c91de23a1f15cc6e279133a63d 497 SMART SM00382 192 356 0.0085 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS15760 46bd94c91de23a1f15cc6e279133a63d 497 Pfam PF00158 Sigma-54 interaction domain 193 347 6.0E-38 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS15760 46bd94c91de23a1f15cc6e279133a63d 497 Gene3D G3DSA:3.40.50.300 157 356 3.2E-32 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS15760 46bd94c91de23a1f15cc6e279133a63d 497 PANTHER PTHR32071:SF33 123 176 3.6E-67 T 22-04-2016 HRM2_RS15760 46bd94c91de23a1f15cc6e279133a63d 497 PANTHER PTHR32071:SF33 192 420 3.6E-67 T 22-04-2016 HRM2_RS15760 46bd94c91de23a1f15cc6e279133a63d 497 PANTHER PTHR32071 123 176 3.6E-67 T 22-04-2016 HRM2_RS15760 46bd94c91de23a1f15cc6e279133a63d 497 PANTHER PTHR32071 192 420 3.6E-67 T 22-04-2016 HRM2_RS19680 600a0eaa70c8911d346591361e4f0bc3 414 Gene3D G3DSA:1.20.140.10 247 409 6.5E-42 T 22-04-2016 HRM2_RS19680 600a0eaa70c8911d346591361e4f0bc3 414 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 137 245 1.4E-17 T 22-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 HRM2_RS19680 600a0eaa70c8911d346591361e4f0bc3 414 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 98 2.3E-10 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS19680 600a0eaa70c8911d346591361e4f0bc3 414 Gene3D G3DSA:2.40.110.10 136 246 8.1E-33 T 22-04-2016 HRM2_RS19680 600a0eaa70c8911d346591361e4f0bc3 414 SUPERFAMILY SSF56645 7 254 1.07E-48 T 22-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 HRM2_RS19680 600a0eaa70c8911d346591361e4f0bc3 414 SUPERFAMILY SSF47203 266 406 2.58E-35 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS19680 600a0eaa70c8911d346591361e4f0bc3 414 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 365 384 - T 22-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 HRM2_RS19680 600a0eaa70c8911d346591361e4f0bc3 414 PANTHER PTHR10909 164 399 2.1E-80 T 22-04-2016 HRM2_RS19680 600a0eaa70c8911d346591361e4f0bc3 414 PANTHER PTHR10909 2 148 2.1E-80 T 22-04-2016 HRM2_RS19680 600a0eaa70c8911d346591361e4f0bc3 414 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 272 399 1.4E-29 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS19680 600a0eaa70c8911d346591361e4f0bc3 414 Gene3D G3DSA:1.10.540.10 3 104 9.3E-16 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS16280 f53b0efd4cc09b8d3c4511be3b5d82b2 220 PANTHER PTHR23026:SF90 1 218 4.1E-40 T 22-04-2016 HRM2_RS16280 f53b0efd4cc09b8d3c4511be3b5d82b2 220 SUPERFAMILY SSF55469 1 217 2.22E-42 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 HRM2_RS16280 f53b0efd4cc09b8d3c4511be3b5d82b2 220 Pfam PF00881 Nitroreductase family 7 195 4.8E-27 T 22-04-2016 IPR029479 Nitroreductase HRM2_RS16280 f53b0efd4cc09b8d3c4511be3b5d82b2 220 Gene3D G3DSA:3.40.109.10 2 217 1.2E-43 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 HRM2_RS16280 f53b0efd4cc09b8d3c4511be3b5d82b2 220 PANTHER PTHR23026 1 218 4.1E-40 T 22-04-2016 HRM2_RS25410 74a8eeabeaa113fef7c6c4639e477b48 873 Pfam PF13487 HD domain 746 807 5.2E-17 T 22-04-2016 HRM2_RS25410 74a8eeabeaa113fef7c6c4639e477b48 873 Gene3D G3DSA:1.10.287.130 241 314 2.6E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25410 74a8eeabeaa113fef7c6c4639e477b48 873 SMART SM00388 250 318 1.9E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25410 74a8eeabeaa113fef7c6c4639e477b48 873 Pfam PF00512 His Kinase A (phospho-acceptor) domain 251 318 4.2E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25410 74a8eeabeaa113fef7c6c4639e477b48 873 Gene3D G3DSA:3.30.565.10 320 480 4.9E-44 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25410 74a8eeabeaa113fef7c6c4639e477b48 873 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 365 473 3.9E-27 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25410 74a8eeabeaa113fef7c6c4639e477b48 873 SUPERFAMILY SSF109604 684 854 1.11E-33 T 22-04-2016 HRM2_RS25410 74a8eeabeaa113fef7c6c4639e477b48 873 SMART SM00387 364 475 7.7E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25410 74a8eeabeaa113fef7c6c4639e477b48 873 SMART SM00471 691 826 8.5E-8 T 22-04-2016 IPR003607 HD/PDEase domain HRM2_RS25410 74a8eeabeaa113fef7c6c4639e477b48 873 Pfam PF00072 Response regulator receiver domain 549 658 1.7E-24 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS25410 74a8eeabeaa113fef7c6c4639e477b48 873 PANTHER PTHR24423 517 675 6.0E-109 T 22-04-2016 HRM2_RS25410 74a8eeabeaa113fef7c6c4639e477b48 873 PANTHER PTHR24423 235 478 6.0E-109 T 22-04-2016 HRM2_RS25410 74a8eeabeaa113fef7c6c4639e477b48 873 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 472 3.8E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25410 74a8eeabeaa113fef7c6c4639e477b48 873 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 414 3.8E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25410 74a8eeabeaa113fef7c6c4639e477b48 873 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 453 3.8E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25410 74a8eeabeaa113fef7c6c4639e477b48 873 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 428 3.8E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25410 74a8eeabeaa113fef7c6c4639e477b48 873 Gene3D G3DSA:3.40.50.2300 544 673 1.8E-39 T 22-04-2016 HRM2_RS25410 74a8eeabeaa113fef7c6c4639e477b48 873 Gene3D G3DSA:1.10.3210.10 691 857 5.8E-20 T 22-04-2016 IPR006674 HD domain HRM2_RS25410 74a8eeabeaa113fef7c6c4639e477b48 873 SUPERFAMILY SSF52172 545 677 1.57E-38 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS25410 74a8eeabeaa113fef7c6c4639e477b48 873 SUPERFAMILY SSF55874 307 473 1.7E-44 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25410 74a8eeabeaa113fef7c6c4639e477b48 873 SMART SM00448 547 658 6.1E-37 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS25410 74a8eeabeaa113fef7c6c4639e477b48 873 SUPERFAMILY SSF47384 236 318 1.8E-17 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS04160 c082dd6f696c4a2e70a6d50cfa3a06e5 443 Pfam PF02754 Cysteine-rich domain 334 417 8.0E-10 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS04160 c082dd6f696c4a2e70a6d50cfa3a06e5 443 Pfam PF02754 Cysteine-rich domain 170 253 9.2E-15 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS04160 c082dd6f696c4a2e70a6d50cfa3a06e5 443 PANTHER PTHR32479:SF13 296 441 1.9E-55 T 22-04-2016 HRM2_RS04160 c082dd6f696c4a2e70a6d50cfa3a06e5 443 PANTHER PTHR32479:SF13 1 265 1.9E-55 T 22-04-2016 HRM2_RS04160 c082dd6f696c4a2e70a6d50cfa3a06e5 443 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 62 73 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS04160 c082dd6f696c4a2e70a6d50cfa3a06e5 443 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 11 22 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS04160 c082dd6f696c4a2e70a6d50cfa3a06e5 443 Gene3D G3DSA:1.10.1060.10 5 91 1.9E-19 T 22-04-2016 HRM2_RS04160 c082dd6f696c4a2e70a6d50cfa3a06e5 443 SUPERFAMILY SSF46548 8 90 2.09E-18 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS04160 c082dd6f696c4a2e70a6d50cfa3a06e5 443 PANTHER PTHR32479 296 441 1.9E-55 T 22-04-2016 HRM2_RS04160 c082dd6f696c4a2e70a6d50cfa3a06e5 443 PANTHER PTHR32479 1 265 1.9E-55 T 22-04-2016 HRM2_RS04160 c082dd6f696c4a2e70a6d50cfa3a06e5 443 Pfam PF13183 4Fe-4S dicluster domain 8 76 1.4E-13 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS07185 e2fa57b2dc1ecb95626c573452f74bfb 800 Pfam PF03104 DNA polymerase family B, exonuclease domain 76 325 4.9E-15 T 22-04-2016 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS07185 e2fa57b2dc1ecb95626c573452f74bfb 800 Gene3D G3DSA:1.10.287.690 490 529 8.1E-4 T 22-04-2016 HRM2_RS07185 e2fa57b2dc1ecb95626c573452f74bfb 800 ProSitePatterns PS00116 DNA polymerase family B signature. 568 576 - T 22-04-2016 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS07185 e2fa57b2dc1ecb95626c573452f74bfb 800 Gene3D G3DSA:3.30.420.10 147 184 1.2E-28 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS07185 e2fa57b2dc1ecb95626c573452f74bfb 800 Gene3D G3DSA:3.30.420.10 223 395 1.2E-28 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS07185 e2fa57b2dc1ecb95626c573452f74bfb 800 Gene3D G3DSA:3.90.1600.10 537 620 8.3E-12 T 22-04-2016 IPR023211 DNA polymerase, palm domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS07185 e2fa57b2dc1ecb95626c573452f74bfb 800 Gene3D G3DSA:3.90.1600.10 430 461 8.3E-12 T 22-04-2016 IPR023211 DNA polymerase, palm domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS07185 e2fa57b2dc1ecb95626c573452f74bfb 800 SMART SM00486 147 580 1.4E-50 T 22-04-2016 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS07185 e2fa57b2dc1ecb95626c573452f74bfb 800 PANTHER PTHR10322:SF23 75 781 3.6E-98 T 22-04-2016 HRM2_RS07185 e2fa57b2dc1ecb95626c573452f74bfb 800 Pfam PF00136 DNA polymerase family B 405 741 7.6E-42 T 22-04-2016 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS07185 e2fa57b2dc1ecb95626c573452f74bfb 800 PANTHER PTHR10322 75 781 3.6E-98 T 22-04-2016 HRM2_RS07185 e2fa57b2dc1ecb95626c573452f74bfb 800 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 566 574 1.5E-10 T 22-04-2016 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS07185 e2fa57b2dc1ecb95626c573452f74bfb 800 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 445 458 1.5E-10 T 22-04-2016 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS07185 e2fa57b2dc1ecb95626c573452f74bfb 800 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 514 526 1.5E-10 T 22-04-2016 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS07185 e2fa57b2dc1ecb95626c573452f74bfb 800 SUPERFAMILY SSF53098 7 181 7.59E-61 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS07185 e2fa57b2dc1ecb95626c573452f74bfb 800 SUPERFAMILY SSF53098 223 418 7.59E-61 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS07185 e2fa57b2dc1ecb95626c573452f74bfb 800 SUPERFAMILY SSF56672 413 793 1.78E-90 T 22-04-2016 HRM2_RS06100 7f3f34d9ef5aff0eaaaf389f8d659829 716 Pfam PF02824 TGS domain 388 447 4.0E-22 T 22-04-2016 IPR004095 TGS KEGG: 00970+6.1.1.3 HRM2_RS06100 7f3f34d9ef5aff0eaaaf389f8d659829 716 PANTHER PTHR21262 4 714 0.0 T 22-04-2016 HRM2_RS06100 7f3f34d9ef5aff0eaaaf389f8d659829 716 SUPERFAMILY SSF55021 637 713 2.7E-9 T 22-04-2016 HRM2_RS06100 7f3f34d9ef5aff0eaaaf389f8d659829 716 SUPERFAMILY SSF81301 182 392 3.27E-63 T 22-04-2016 HRM2_RS06100 7f3f34d9ef5aff0eaaaf389f8d659829 716 SMART SM00471 41 153 4.9E-11 T 22-04-2016 IPR003607 HD/PDEase domain HRM2_RS06100 7f3f34d9ef5aff0eaaaf389f8d659829 716 Pfam PF04607 Region found in RelA / SpoT proteins 236 345 6.1E-36 T 22-04-2016 IPR007685 RelA/SpoT GO:0015969 HRM2_RS06100 7f3f34d9ef5aff0eaaaf389f8d659829 716 PANTHER PTHR21262:SF0 4 714 0.0 T 22-04-2016 HRM2_RS06100 7f3f34d9ef5aff0eaaaf389f8d659829 716 SUPERFAMILY SSF109604 3 192 1.1E-70 T 22-04-2016 HRM2_RS06100 7f3f34d9ef5aff0eaaaf389f8d659829 716 Pfam PF13328 HD domain 26 176 1.1E-51 T 22-04-2016 IPR003607 HD/PDEase domain HRM2_RS06100 7f3f34d9ef5aff0eaaaf389f8d659829 716 SUPERFAMILY SSF81271 375 447 6.21E-22 T 22-04-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 HRM2_RS06100 7f3f34d9ef5aff0eaaaf389f8d659829 716 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 26 711 2.7E-237 T 22-04-2016 IPR004811 RelA/SpoT family GO:0015969 HRM2_RS06100 7f3f34d9ef5aff0eaaaf389f8d659829 716 SMART SM00954 236 346 2.2E-57 T 22-04-2016 IPR007685 RelA/SpoT GO:0015969 HRM2_RS06100 7f3f34d9ef5aff0eaaaf389f8d659829 716 Gene3D G3DSA:3.10.20.30 387 449 2.9E-22 T 22-04-2016 IPR012675 Beta-grasp domain HRM2_RS06100 7f3f34d9ef5aff0eaaaf389f8d659829 716 Gene3D G3DSA:3.30.460.10 179 326 2.2E-47 T 22-04-2016 HRM2_RS06100 7f3f34d9ef5aff0eaaaf389f8d659829 716 Pfam PF13291 ACT domain 635 711 2.9E-16 T 22-04-2016 IPR002912 ACT domain GO:0008152|GO:0016597 HRM2_RS06100 7f3f34d9ef5aff0eaaaf389f8d659829 716 Gene3D G3DSA:3.30.70.260 637 710 1.7E-12 T 22-04-2016 HRM2_RS03310 e160aa1576ec8af3dbc10e1ac2317f20 112 SUPERFAMILY SSF54913 1 112 5.08E-47 T 22-04-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta HRM2_RS03310 e160aa1576ec8af3dbc10e1ac2317f20 112 PIRSF PIRSF039144 1 112 7.7E-58 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HRM2_RS03310 e160aa1576ec8af3dbc10e1ac2317f20 112 PANTHER PTHR30115 1 112 4.5E-65 T 22-04-2016 HRM2_RS03310 e160aa1576ec8af3dbc10e1ac2317f20 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 9.8E-45 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HRM2_RS03310 e160aa1576ec8af3dbc10e1ac2317f20 112 SMART SM00938 4 105 1.4E-67 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HRM2_RS03310 e160aa1576ec8af3dbc10e1ac2317f20 112 Gene3D G3DSA:3.30.70.120 1 112 2.9E-51 T 22-04-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal HRM2_RS03310 e160aa1576ec8af3dbc10e1ac2317f20 112 PRINTS PR00340 P-II protein signature 2 17 2.7E-44 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HRM2_RS03310 e160aa1576ec8af3dbc10e1ac2317f20 112 PRINTS PR00340 P-II protein signature 83 103 2.7E-44 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HRM2_RS03310 e160aa1576ec8af3dbc10e1ac2317f20 112 PRINTS PR00340 P-II protein signature 52 75 2.7E-44 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HRM2_RS03310 e160aa1576ec8af3dbc10e1ac2317f20 112 PRINTS PR00340 P-II protein signature 23 41 2.7E-44 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HRM2_RS03310 e160aa1576ec8af3dbc10e1ac2317f20 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 22-04-2016 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 HRM2_RS03310 e160aa1576ec8af3dbc10e1ac2317f20 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 22-04-2016 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 HRM2_RS16005 08342d4c847661f70b1372668631971d 310 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 108 213 3.6E-13 T 22-04-2016 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 UniPathway: UPA00223 HRM2_RS16005 08342d4c847661f70b1372668631971d 310 Gene3D G3DSA:1.20.950.10 7 243 2.7E-82 T 22-04-2016 HRM2_RS16005 08342d4c847661f70b1372668631971d 310 SUPERFAMILY SSF81343 10 241 1.83E-65 T 22-04-2016 HRM2_RS13905 e6720cb8192b3c4d63a975b368351cc8 685 Pfam PF14520 Helix-hairpin-helix domain 462 511 1.4E-5 T 22-04-2016 HRM2_RS13905 e6720cb8192b3c4d63a975b368351cc8 685 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 333 410 1.1E-32 T 22-04-2016 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 HRM2_RS13905 e6720cb8192b3c4d63a975b368351cc8 685 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 343 358 - T 22-04-2016 IPR033136 NAD-dependent DNA ligase, conserved site HRM2_RS13905 e6720cb8192b3c4d63a975b368351cc8 685 Gene3D G3DSA:3.30.470.30 125 264 7.0E-46 T 22-04-2016 HRM2_RS13905 e6720cb8192b3c4d63a975b368351cc8 685 SMART SM00532 10 459 5.7E-242 T 22-04-2016 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 HRM2_RS13905 e6720cb8192b3c4d63a975b368351cc8 685 SUPERFAMILY SSF47781 415 594 1.26E-55 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 HRM2_RS13905 e6720cb8192b3c4d63a975b368351cc8 685 Gene3D G3DSA:2.40.50.140 332 402 7.1E-32 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS13905 e6720cb8192b3c4d63a975b368351cc8 685 SMART SM00292 608 685 1.7E-12 T 22-04-2016 IPR001357 BRCT domain HRM2_RS13905 e6720cb8192b3c4d63a975b368351cc8 685 PIRSF PIRSF001604 3 685 4.1E-242 T 22-04-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 HRM2_RS13905 e6720cb8192b3c4d63a975b368351cc8 685 Gene3D G3DSA:3.40.50.10190 608 685 8.8E-21 T 22-04-2016 IPR001357 BRCT domain HRM2_RS13905 e6720cb8192b3c4d63a975b368351cc8 685 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 18 678 4.7E-248 T 22-04-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 HRM2_RS13905 e6720cb8192b3c4d63a975b368351cc8 685 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 419 445 3.0E-8 T 22-04-2016 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 HRM2_RS13905 e6720cb8192b3c4d63a975b368351cc8 685 Gene3D G3DSA:1.10.287.610 7 74 1.0E-24 T 22-04-2016 HRM2_RS13905 e6720cb8192b3c4d63a975b368351cc8 685 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 609 681 1.9E-11 T 22-04-2016 IPR001357 BRCT domain HRM2_RS13905 e6720cb8192b3c4d63a975b368351cc8 685 Pfam PF12826 Helix-hairpin-helix motif 521 584 1.9E-18 T 22-04-2016 HRM2_RS13905 e6720cb8192b3c4d63a975b368351cc8 685 Gene3D G3DSA:1.10.150.20 515 595 1.6E-24 T 22-04-2016 HRM2_RS13905 e6720cb8192b3c4d63a975b368351cc8 685 SMART SM00278 491 510 57.0 T 22-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HRM2_RS13905 e6720cb8192b3c4d63a975b368351cc8 685 SMART SM00278 555 574 0.42 T 22-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HRM2_RS13905 e6720cb8192b3c4d63a975b368351cc8 685 SUPERFAMILY SSF52113 608 684 3.36E-18 T 22-04-2016 IPR001357 BRCT domain HRM2_RS13905 e6720cb8192b3c4d63a975b368351cc8 685 Hamap MF_01588 DNA ligase [ligA]. 9 682 50.176 T 22-04-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 HRM2_RS13905 e6720cb8192b3c4d63a975b368351cc8 685 SUPERFAMILY SSF50249 331 412 9.59E-27 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS13905 e6720cb8192b3c4d63a975b368351cc8 685 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 11 329 5.6E-118 T 22-04-2016 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 HRM2_RS13905 e6720cb8192b3c4d63a975b368351cc8 685 PANTHER PTHR23389:SF9 10 536 4.4E-181 T 22-04-2016 HRM2_RS13905 e6720cb8192b3c4d63a975b368351cc8 685 Gene3D G3DSA:1.10.150.20 446 514 1.8E-26 T 22-04-2016 HRM2_RS13905 e6720cb8192b3c4d63a975b368351cc8 685 PANTHER PTHR23389 10 536 4.4E-181 T 22-04-2016 HRM2_RS13905 e6720cb8192b3c4d63a975b368351cc8 685 SUPERFAMILY SSF56091 8 328 8.82E-109 T 22-04-2016 HRM2_RS05275 5617d93fa4b2a34b9d1aede156509a0d 246 PANTHER PTHR18968:SF117 3 242 3.5E-112 T 22-04-2016 HRM2_RS05275 5617d93fa4b2a34b9d1aede156509a0d 246 Gene3D G3DSA:3.40.50.970 16 230 3.1E-56 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS05275 5617d93fa4b2a34b9d1aede156509a0d 246 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 51 208 1.3E-23 T 22-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HRM2_RS05275 5617d93fa4b2a34b9d1aede156509a0d 246 PANTHER PTHR18968 3 242 3.5E-112 T 22-04-2016 HRM2_RS05275 5617d93fa4b2a34b9d1aede156509a0d 246 SUPERFAMILY SSF52518 15 241 1.81E-53 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS16590 913e42241150a1abad734498c80a236a 280 SMART SM00382 53 189 1.9E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS16590 913e42241150a1abad734498c80a236a 280 SUPERFAMILY SSF52540 18 270 1.19E-21 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16590 913e42241150a1abad734498c80a236a 280 Pfam PF13401 AAA domain 53 183 3.0E-14 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS16590 913e42241150a1abad734498c80a236a 280 PANTHER PTHR35894 14 270 1.4E-26 T 22-04-2016 HRM2_RS16590 913e42241150a1abad734498c80a236a 280 Gene3D G3DSA:3.40.50.300 46 177 1.2E-9 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18160 913e42241150a1abad734498c80a236a 280 SMART SM00382 53 189 1.9E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS18160 913e42241150a1abad734498c80a236a 280 SUPERFAMILY SSF52540 18 270 1.19E-21 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18160 913e42241150a1abad734498c80a236a 280 Pfam PF13401 AAA domain 53 183 3.0E-14 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS18160 913e42241150a1abad734498c80a236a 280 PANTHER PTHR35894 14 270 1.4E-26 T 22-04-2016 HRM2_RS18160 913e42241150a1abad734498c80a236a 280 Gene3D G3DSA:3.40.50.300 46 177 1.2E-9 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14525 d813602f509ec46afaef950f453e775a 618 SUPERFAMILY SSF88659 514 615 5.23E-24 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS14525 d813602f509ec46afaef950f453e775a 618 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 408 421 - T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS14525 d813602f509ec46afaef950f453e775a 618 Pfam PF03979 Sigma-70 factor, region 1.1 16 78 2.3E-15 T 22-04-2016 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 HRM2_RS14525 d813602f509ec46afaef950f453e775a 618 Gene3D G3DSA:1.10.10.10 547 616 1.1E-30 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS14525 d813602f509ec46afaef950f453e775a 618 Pfam PF00140 Sigma-70 factor, region 1.2 124 156 3.1E-11 T 22-04-2016 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS14525 d813602f509ec46afaef950f453e775a 618 Pfam PF04545 Sigma-70, region 4 552 605 1.1E-17 T 22-04-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS14525 d813602f509ec46afaef950f453e775a 618 Pfam PF04542 Sigma-70 region 2 384 453 7.5E-22 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS14525 d813602f509ec46afaef950f453e775a 618 SUPERFAMILY SSF88659 457 530 4.42E-21 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS14525 d813602f509ec46afaef950f453e775a 618 PRINTS PR00046 Major sigma-70 factor signature 432 440 1.4E-30 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS14525 d813602f509ec46afaef950f453e775a 618 PRINTS PR00046 Major sigma-70 factor signature 592 603 1.4E-30 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS14525 d813602f509ec46afaef950f453e775a 618 PRINTS PR00046 Major sigma-70 factor signature 556 568 1.4E-30 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS14525 d813602f509ec46afaef950f453e775a 618 PRINTS PR00046 Major sigma-70 factor signature 577 592 1.4E-30 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS14525 d813602f509ec46afaef950f453e775a 618 PRINTS PR00046 Major sigma-70 factor signature 408 421 1.4E-30 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS14525 d813602f509ec46afaef950f453e775a 618 PANTHER PTHR30603 97 178 1.0E-197 T 22-04-2016 HRM2_RS14525 d813602f509ec46afaef950f453e775a 618 PANTHER PTHR30603 338 618 1.0E-197 T 22-04-2016 HRM2_RS14525 d813602f509ec46afaef950f453e775a 618 PANTHER PTHR30603 20 81 1.0E-197 T 22-04-2016 HRM2_RS14525 d813602f509ec46afaef950f453e775a 618 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 577 603 - T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS14525 d813602f509ec46afaef950f453e775a 618 PANTHER PTHR30603:SF0 97 178 1.0E-197 T 22-04-2016 HRM2_RS14525 d813602f509ec46afaef950f453e775a 618 PANTHER PTHR30603:SF0 338 618 1.0E-197 T 22-04-2016 HRM2_RS14525 d813602f509ec46afaef950f453e775a 618 PANTHER PTHR30603:SF0 20 81 1.0E-197 T 22-04-2016 HRM2_RS14525 d813602f509ec46afaef950f453e775a 618 Pfam PF04539 Sigma-70 region 3 463 538 4.2E-29 T 22-04-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS14525 d813602f509ec46afaef950f453e775a 618 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 3 617 36.118 T 22-04-2016 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 HRM2_RS14525 d813602f509ec46afaef950f453e775a 618 SUPERFAMILY SSF88946 141 451 1.19E-61 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS14525 d813602f509ec46afaef950f453e775a 618 Gene3D G3DSA:1.10.601.10 138 453 1.0E-77 T 22-04-2016 HRM2_RS14525 d813602f509ec46afaef950f453e775a 618 Gene3D G3DSA:1.10.10.10 457 508 1.2E-24 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS14525 d813602f509ec46afaef950f453e775a 618 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 381 605 8.1E-37 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS14525 d813602f509ec46afaef950f453e775a 618 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 380 616 1.1E-120 T 22-04-2016 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 HRM2_RS02790 1d36ad4234984f786da79305ac94860c 555 SUPERFAMILY SSF47384 321 396 8.63E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS02790 1d36ad4234984f786da79305ac94860c 555 Gene3D G3DSA:3.30.565.10 383 553 4.5E-35 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS02790 1d36ad4234984f786da79305ac94860c 555 PANTHER PTHR24423:SF360 310 555 9.9E-50 T 22-04-2016 HRM2_RS02790 1d36ad4234984f786da79305ac94860c 555 Gene3D G3DSA:1.10.287.130 321 382 3.1E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS02790 1d36ad4234984f786da79305ac94860c 555 PANTHER PTHR24423 310 555 9.9E-50 T 22-04-2016 HRM2_RS02790 1d36ad4234984f786da79305ac94860c 555 SMART SM00388 326 396 4.4E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS02790 1d36ad4234984f786da79305ac94860c 555 SUPERFAMILY SSF55874 386 551 8.91E-35 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS02790 1d36ad4234984f786da79305ac94860c 555 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 439 552 3.5E-21 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS02790 1d36ad4234984f786da79305ac94860c 555 Pfam PF00512 His Kinase A (phospho-acceptor) domain 326 394 1.1E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS02790 1d36ad4234984f786da79305ac94860c 555 Gene3D G3DSA:3.30.450.20 170 274 3.6E-4 T 22-04-2016 HRM2_RS02790 1d36ad4234984f786da79305ac94860c 555 PRINTS PR00344 Bacterial sensor protein C-terminal signature 477 491 1.3E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS02790 1d36ad4234984f786da79305ac94860c 555 PRINTS PR00344 Bacterial sensor protein C-terminal signature 495 505 1.3E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS02790 1d36ad4234984f786da79305ac94860c 555 PRINTS PR00344 Bacterial sensor protein C-terminal signature 508 526 1.3E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS02790 1d36ad4234984f786da79305ac94860c 555 PRINTS PR00344 Bacterial sensor protein C-terminal signature 537 550 1.3E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS02790 1d36ad4234984f786da79305ac94860c 555 Pfam PF02743 Cache domain 37 260 3.8E-14 T 22-04-2016 IPR033479 Double Cache domain 1 HRM2_RS02790 1d36ad4234984f786da79305ac94860c 555 SMART SM00387 438 553 3.6E-32 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS20410 b1eb1ec200abf911791cc44ca9ad2d9a 272 PANTHER PTHR30363 15 266 4.2E-72 T 22-04-2016 HRM2_RS20410 b1eb1ec200abf911791cc44ca9ad2d9a 272 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 52 70 1.8E-7 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 HRM2_RS20410 b1eb1ec200abf911791cc44ca9ad2d9a 272 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 52 1.8E-7 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 HRM2_RS20410 b1eb1ec200abf911791cc44ca9ad2d9a 272 SUPERFAMILY SSF100950 87 244 2.56E-21 T 22-04-2016 HRM2_RS20410 b1eb1ec200abf911791cc44ca9ad2d9a 272 SMART SM00420 20 72 1.4E-16 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 HRM2_RS20410 b1eb1ec200abf911791cc44ca9ad2d9a 272 Gene3D G3DSA:1.10.10.10 15 69 4.0E-9 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS20410 b1eb1ec200abf911791cc44ca9ad2d9a 272 ProSitePatterns PS00894 DeoR-type HTH domain signature. 20 54 - T 22-04-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 HRM2_RS20410 b1eb1ec200abf911791cc44ca9ad2d9a 272 PANTHER PTHR30363:SF1 15 266 4.2E-72 T 22-04-2016 HRM2_RS20410 b1eb1ec200abf911791cc44ca9ad2d9a 272 Pfam PF00455 DeoR C terminal sensor domain 88 245 6.1E-35 T 22-04-2016 IPR014036 DeoR C-terminal sensor domain HRM2_RS20410 b1eb1ec200abf911791cc44ca9ad2d9a 272 Pfam PF08220 DeoR-like helix-turn-helix domain 20 72 6.2E-17 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 HRM2_RS20410 b1eb1ec200abf911791cc44ca9ad2d9a 272 SMART SM01134 86 247 1.4E-42 T 22-04-2016 HRM2_RS20410 b1eb1ec200abf911791cc44ca9ad2d9a 272 SUPERFAMILY SSF46785 17 89 1.32E-11 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS20410 b1eb1ec200abf911791cc44ca9ad2d9a 272 Gene3D G3DSA:3.30.750.70 89 166 4.4E-10 T 22-04-2016 HRM2_RS22270 ef8334696d107acce283e17d6202f3ff 73 Pfam PF13689 Domain of unknown function (DUF4154) 29 71 3.7E-9 T 22-04-2016 IPR025293 Protein of unknown function DUF4154 HRM2_RS01600 c43c3e933215255c71a4ee2edcdc9320 449 Gene3D G3DSA:1.10.285.10 374 448 2.0E-26 T 22-04-2016 HRM2_RS01600 c43c3e933215255c71a4ee2edcdc9320 449 Gene3D G3DSA:1.10.285.10 8 61 8.9E-24 T 22-04-2016 HRM2_RS01600 c43c3e933215255c71a4ee2edcdc9320 449 PIRSF PIRSF000185 16 449 9.4E-115 T 22-04-2016 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 HRM2_RS01600 c43c3e933215255c71a4ee2edcdc9320 449 SUPERFAMILY SSF51735 196 448 4.45E-74 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS01600 c43c3e933215255c71a4ee2edcdc9320 449 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 51 179 8.9E-49 T 22-04-2016 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 HRM2_RS01600 c43c3e933215255c71a4ee2edcdc9320 449 Gene3D G3DSA:3.40.192.10 62 183 7.2E-61 T 22-04-2016 HRM2_RS01600 c43c3e933215255c71a4ee2edcdc9320 449 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 116 129 - T 22-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 HRM2_RS01600 c43c3e933215255c71a4ee2edcdc9320 449 SMART SM00839 198 447 2.6E-92 T 22-04-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 HRM2_RS01600 c43c3e933215255c71a4ee2edcdc9320 449 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 108 122 6.6E-31 T 22-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 HRM2_RS01600 c43c3e933215255c71a4ee2edcdc9320 449 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 187 209 6.6E-31 T 22-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 HRM2_RS01600 c43c3e933215255c71a4ee2edcdc9320 449 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 373 384 6.6E-31 T 22-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 HRM2_RS01600 c43c3e933215255c71a4ee2edcdc9320 449 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 229 249 6.6E-31 T 22-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 HRM2_RS01600 c43c3e933215255c71a4ee2edcdc9320 449 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 196 447 4.4E-84 T 22-04-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 HRM2_RS01600 c43c3e933215255c71a4ee2edcdc9320 449 PANTHER PTHR11606:SF4 5 449 3.7E-251 T 22-04-2016 HRM2_RS01600 c43c3e933215255c71a4ee2edcdc9320 449 SUPERFAMILY SSF53223 6 190 5.76E-72 T 22-04-2016 HRM2_RS01600 c43c3e933215255c71a4ee2edcdc9320 449 PANTHER PTHR11606 5 449 3.7E-251 T 22-04-2016 HRM2_RS01600 c43c3e933215255c71a4ee2edcdc9320 449 Gene3D G3DSA:3.40.50.720 203 373 1.8E-60 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS11095 56c1f8dfea58160611be33282c78709b 407 Pfam PF02687 FtsX-like permease family 276 400 4.2E-18 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 HRM2_RS11095 56c1f8dfea58160611be33282c78709b 407 PANTHER PTHR30489:SF8 1 407 1.6E-89 T 22-04-2016 HRM2_RS11095 56c1f8dfea58160611be33282c78709b 407 Pfam PF12704 MacB-like periplasmic core domain 25 243 3.2E-18 T 22-04-2016 IPR025857 MacB-like periplasmic core domain HRM2_RS11095 56c1f8dfea58160611be33282c78709b 407 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 2 406 8.6E-120 T 22-04-2016 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 HRM2_RS11095 56c1f8dfea58160611be33282c78709b 407 PANTHER PTHR30489 1 407 1.6E-89 T 22-04-2016 HRM2_RS17535 6dca23c7db43c7c50ce4b623699f57e2 533 Gene3D G3DSA:3.30.70.870 398 465 1.4E-10 T 22-04-2016 HRM2_RS17535 6dca23c7db43c7c50ce4b623699f57e2 533 PANTHER PTHR23115:SF69 254 503 1.8E-231 T 22-04-2016 HRM2_RS17535 6dca23c7db43c7c50ce4b623699f57e2 533 PANTHER PTHR23115:SF69 1 188 1.8E-231 T 22-04-2016 HRM2_RS17535 6dca23c7db43c7c50ce4b623699f57e2 533 SUPERFAMILY SSF54980 396 468 6.12E-14 T 22-04-2016 IPR009022 Elongation factor G, III-V domain HRM2_RS17535 6dca23c7db43c7c50ce4b623699f57e2 533 PRINTS PR00315 GTP-binding elongation factor signature 69 77 1.5E-12 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS17535 6dca23c7db43c7c50ce4b623699f57e2 533 PRINTS PR00315 GTP-binding elongation factor signature 89 99 1.5E-12 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS17535 6dca23c7db43c7c50ce4b623699f57e2 533 PRINTS PR00315 GTP-binding elongation factor signature 105 116 1.5E-12 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS17535 6dca23c7db43c7c50ce4b623699f57e2 533 PRINTS PR00315 GTP-binding elongation factor signature 19 32 1.5E-12 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS17535 6dca23c7db43c7c50ce4b623699f57e2 533 PRINTS PR00315 GTP-binding elongation factor signature 141 150 1.5E-12 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS17535 6dca23c7db43c7c50ce4b623699f57e2 533 SUPERFAMILY SSF52540 14 280 5.85E-84 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17535 6dca23c7db43c7c50ce4b623699f57e2 533 Pfam PF16658 Class II release factor RF3, C-terminal domain 390 515 1.9E-43 T 22-04-2016 IPR032090 Peptide chain release factor 3, C-terminal HRM2_RS17535 6dca23c7db43c7c50ce4b623699f57e2 533 SUPERFAMILY SSF50447 264 396 1.67E-29 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain HRM2_RS17535 6dca23c7db43c7c50ce4b623699f57e2 533 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 19 153 2.6E-23 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HRM2_RS17535 6dca23c7db43c7c50ce4b623699f57e2 533 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 11 531 1.9E-227 T 22-04-2016 IPR004548 Peptide chain release factor 3 GO:0005525|GO:0005737|GO:0006415|GO:0016149 HRM2_RS17535 6dca23c7db43c7c50ce4b623699f57e2 533 PANTHER PTHR23115 254 503 1.8E-231 T 22-04-2016 HRM2_RS17535 6dca23c7db43c7c50ce4b623699f57e2 533 PANTHER PTHR23115 1 188 1.8E-231 T 22-04-2016 HRM2_RS17535 6dca23c7db43c7c50ce4b623699f57e2 533 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 8 530 50.787 T 22-04-2016 IPR004548 Peptide chain release factor 3 GO:0005525|GO:0005737|GO:0006415|GO:0016149 HRM2_RS17535 6dca23c7db43c7c50ce4b623699f57e2 533 Pfam PF03144 Elongation factor Tu domain 2 317 383 5.8E-8 T 22-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 HRM2_RS17535 6dca23c7db43c7c50ce4b623699f57e2 533 Gene3D G3DSA:3.40.50.300 12 285 7.0E-65 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17535 6dca23c7db43c7c50ce4b623699f57e2 533 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 62 77 - T 22-04-2016 IPR031157 Tr-type G domain, conserved site HRM2_RS17535 6dca23c7db43c7c50ce4b623699f57e2 533 Gene3D G3DSA:2.40.30.10 295 397 3.5E-23 T 22-04-2016 HRM2_RS17535 6dca23c7db43c7c50ce4b623699f57e2 533 Pfam PF00009 Elongation factor Tu GTP binding domain 17 280 1.7E-51 T 22-04-2016 HRM2_RS20800 60dd60ccf677e3bedc33bb36af53456e 151 Pfam PF13098 Thioredoxin-like domain 40 130 1.3E-16 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS20800 60dd60ccf677e3bedc33bb36af53456e 151 PANTHER PTHR32234 34 141 2.0E-17 T 22-04-2016 HRM2_RS20800 60dd60ccf677e3bedc33bb36af53456e 151 PANTHER PTHR32234:SF0 34 141 2.0E-17 T 22-04-2016 IPR022910 Thiol:disulphide interchange protein DsbD GO:0047134|GO:0055114 HRM2_RS20800 60dd60ccf677e3bedc33bb36af53456e 151 Gene3D G3DSA:3.40.30.10 27 136 1.3E-31 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS20800 60dd60ccf677e3bedc33bb36af53456e 151 SUPERFAMILY SSF52833 27 137 1.4E-31 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS15855 2a0734fc5d9da9616741393ccebf62b4 691 Gene3D G3DSA:1.10.1060.10 632 683 1.6E-10 T 22-04-2016 HRM2_RS15855 2a0734fc5d9da9616741393ccebf62b4 691 Gene3D G3DSA:1.10.1060.10 208 297 1.0E-28 T 22-04-2016 HRM2_RS15855 2a0734fc5d9da9616741393ccebf62b4 691 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 295 598 8.2E-33 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS15855 2a0734fc5d9da9616741393ccebf62b4 691 PANTHER PTHR11938:SF99 203 609 2.0E-105 T 22-04-2016 HRM2_RS15855 2a0734fc5d9da9616741393ccebf62b4 691 PRINTS PR00419 Adrenodoxin reductase family signature 296 318 2.7E-18 T 22-04-2016 HRM2_RS15855 2a0734fc5d9da9616741393ccebf62b4 691 PRINTS PR00419 Adrenodoxin reductase family signature 319 332 2.7E-18 T 22-04-2016 HRM2_RS15855 2a0734fc5d9da9616741393ccebf62b4 691 PRINTS PR00419 Adrenodoxin reductase family signature 428 442 2.7E-18 T 22-04-2016 HRM2_RS15855 2a0734fc5d9da9616741393ccebf62b4 691 PRINTS PR00419 Adrenodoxin reductase family signature 462 475 2.7E-18 T 22-04-2016 HRM2_RS15855 2a0734fc5d9da9616741393ccebf62b4 691 Gene3D G3DSA:3.40.50.720 544 616 2.0E-30 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS15855 2a0734fc5d9da9616741393ccebf62b4 691 Gene3D G3DSA:3.40.50.720 298 385 2.0E-30 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS15855 2a0734fc5d9da9616741393ccebf62b4 691 Gene3D G3DSA:3.30.70.20 138 173 4.0E-13 T 22-04-2016 HRM2_RS15855 2a0734fc5d9da9616741393ccebf62b4 691 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 203 279 3.3E-22 T 22-04-2016 IPR028261 Dihydroprymidine dehydrogenase domain II HRM2_RS15855 2a0734fc5d9da9616741393ccebf62b4 691 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 4 196 4.4E-20 T 22-04-2016 IPR010207 Electron transport complex, RnfB/RsxB GO:0009055|GO:0051536 HRM2_RS15855 2a0734fc5d9da9616741393ccebf62b4 691 PANTHER PTHR11938 203 609 2.0E-105 T 22-04-2016 HRM2_RS15855 2a0734fc5d9da9616741393ccebf62b4 691 SUPERFAMILY SSF46548 598 680 2.88E-5 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS15855 2a0734fc5d9da9616741393ccebf62b4 691 SUPERFAMILY SSF54862 40 190 1.37E-13 T 22-04-2016 HRM2_RS15855 2a0734fc5d9da9616741393ccebf62b4 691 Pfam PF12838 4Fe-4S dicluster domain 138 182 1.0E-7 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS15855 2a0734fc5d9da9616741393ccebf62b4 691 Pfam PF04060 Putative Fe-S cluster 42 73 1.7E-9 T 22-04-2016 IPR007202 4Fe-4S domain GO:0051536 HRM2_RS15855 2a0734fc5d9da9616741393ccebf62b4 691 SUPERFAMILY SSF46548 203 304 4.45E-21 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS15855 2a0734fc5d9da9616741393ccebf62b4 691 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 168 179 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS15855 2a0734fc5d9da9616741393ccebf62b4 691 Gene3D G3DSA:3.50.50.60 386 539 1.6E-44 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS15855 2a0734fc5d9da9616741393ccebf62b4 691 Gene3D G3DSA:3.30.70.20 174 207 4.2E-6 T 22-04-2016 HRM2_RS15855 2a0734fc5d9da9616741393ccebf62b4 691 SUPERFAMILY SSF51971 293 539 1.29E-60 T 22-04-2016 HRM2_RS20805 9ae3f5be9552ae431f344ab878c73bdb 63 SUPERFAMILY SSF63393 4 39 1.8E-5 T 22-04-2016 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 HRM2_RS20805 9ae3f5be9552ae431f344ab878c73bdb 63 Pfam PF09723 Zinc ribbon domain 1 41 1.0E-15 T 22-04-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain HRM2_RS20805 9ae3f5be9552ae431f344ab878c73bdb 63 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 46 3.3E-17 T 22-04-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain HRM2_RS20805 9ae3f5be9552ae431f344ab878c73bdb 63 SMART SM00834 1 42 1.4E-15 T 22-04-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain HRM2_RS20805 9ae3f5be9552ae431f344ab878c73bdb 63 PANTHER PTHR34404 2 47 3.4E-12 T 22-04-2016 HRM2_RS20805 9ae3f5be9552ae431f344ab878c73bdb 63 Gene3D G3DSA:2.20.28.30 5 39 3.6E-5 T 22-04-2016 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 HRM2_RS21065 0614bb0d5dce0f652117debc25c719c6 138 SUPERFAMILY SSF46785 7 67 2.77E-14 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS21065 0614bb0d5dce0f652117debc25c719c6 138 Gene3D G3DSA:1.10.10.10 7 78 3.5E-25 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS21065 0614bb0d5dce0f652117debc25c719c6 138 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 68 133 2.1E-20 T 22-04-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 HRM2_RS21065 0614bb0d5dce0f652117debc25c719c6 138 SMART SM00529 29 129 3.7E-29 T 22-04-2016 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 HRM2_RS21065 0614bb0d5dce0f652117debc25c719c6 138 PANTHER PTHR33238:SF1 6 131 7.0E-38 T 22-04-2016 HRM2_RS21065 0614bb0d5dce0f652117debc25c719c6 138 SUPERFAMILY SSF47979 68 136 6.15E-20 T 22-04-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 HRM2_RS21065 0614bb0d5dce0f652117debc25c719c6 138 Gene3D G3DSA:1.10.60.10 80 133 7.0E-16 T 22-04-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 HRM2_RS21065 0614bb0d5dce0f652117debc25c719c6 138 PANTHER PTHR33238 6 131 7.0E-38 T 22-04-2016 HRM2_RS21065 0614bb0d5dce0f652117debc25c719c6 138 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 7 63 4.2E-16 T 22-04-2016 IPR022687 DTXR-type HTH domain GO:0003677 HRM2_RS01625 d9619a9f1a7200d32e01aaea64cdad59 250 Gene3D G3DSA:3.40.190.10 27 114 5.2E-39 T 22-04-2016 HRM2_RS01625 d9619a9f1a7200d32e01aaea64cdad59 250 Gene3D G3DSA:3.40.190.10 210 247 5.2E-39 T 22-04-2016 HRM2_RS01625 d9619a9f1a7200d32e01aaea64cdad59 250 Gene3D G3DSA:3.40.190.10 115 204 1.9E-17 T 22-04-2016 HRM2_RS01625 d9619a9f1a7200d32e01aaea64cdad59 250 SMART SM00079 28 233 0.0088 T 22-04-2016 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 HRM2_RS01625 d9619a9f1a7200d32e01aaea64cdad59 250 SUPERFAMILY SSF53850 6 248 1.25E-61 T 22-04-2016 HRM2_RS01625 d9619a9f1a7200d32e01aaea64cdad59 250 PANTHER PTHR18966:SF191 27 236 3.4E-36 T 22-04-2016 HRM2_RS01625 d9619a9f1a7200d32e01aaea64cdad59 250 PANTHER PTHR18966 27 236 3.4E-36 T 22-04-2016 HRM2_RS01625 d9619a9f1a7200d32e01aaea64cdad59 250 SMART SM00062 28 243 5.2E-54 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS01625 d9619a9f1a7200d32e01aaea64cdad59 250 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 29 247 2.9E-57 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS22445 e540819e277bf13b09846abf1598394a 120 SUPERFAMILY SSF51735 2 119 2.17E-26 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS22445 e540819e277bf13b09846abf1598394a 120 PANTHER PTHR33303 2 106 2.0E-14 T 22-04-2016 HRM2_RS22445 e540819e277bf13b09846abf1598394a 120 Pfam PF13380 CoA binding domain 3 114 9.2E-28 T 22-04-2016 IPR003781 CoA-binding GO:0048037 HRM2_RS22445 e540819e277bf13b09846abf1598394a 120 Gene3D G3DSA:3.40.50.720 2 118 1.3E-30 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 981 1124 5.4E-8 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 562 808 2.8E-17 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 163 461 1.4E-33 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 Pfam PF12838 4Fe-4S dicluster domain 1327 1375 4.8E-7 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 Gene3D G3DSA:3.50.50.60 1185 1309 2.0E-5 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 Gene3D G3DSA:3.50.50.60 632 813 1.3E-10 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 SUPERFAMILY SSF54862 1292 1386 1.69E-16 T 22-04-2016 HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 SUPERFAMILY SSF54862 1142 1156 1.69E-16 T 22-04-2016 HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 Gene3D G3DSA:3.40.50.720 547 631 5.7E-8 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 Gene3D G3DSA:3.40.50.720 979 1151 2.5E-30 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 Pfam PF00037 4Fe-4S binding domain 19 36 4.3E-6 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 1327 1338 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 Gene3D G3DSA:3.30.70.20 1314 1388 5.9E-16 T 22-04-2016 HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 Gene3D G3DSA:3.30.70.20 16 30 2.6E-11 T 22-04-2016 HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 Gene3D G3DSA:1.10.1060.10 490 546 7.2E-17 T 22-04-2016 HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 Gene3D G3DSA:1.10.1060.10 78 164 9.6E-21 T 22-04-2016 HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 543 554 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 PRINTS PR00419 Adrenodoxin reductase family signature 186 199 1.8E-16 T 22-04-2016 HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 PRINTS PR00419 Adrenodoxin reductase family signature 296 310 1.8E-16 T 22-04-2016 HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 PRINTS PR00419 Adrenodoxin reductase family signature 163 185 1.8E-16 T 22-04-2016 HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 SUPERFAMILY SSF51971 982 1308 9.18E-25 T 22-04-2016 HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 71 149 5.7E-16 T 22-04-2016 IPR028261 Dihydroprymidine dehydrogenase domain II HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 Gene3D G3DSA:3.40.50.720 410 488 1.1E-25 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 Gene3D G3DSA:3.40.50.720 165 253 1.1E-25 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 SUPERFAMILY SSF46548 496 560 1.88E-9 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 PANTHER PTHR11938 71 473 1.8E-96 T 22-04-2016 HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 Gene3D G3DSA:3.50.50.60 254 406 9.5E-44 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 PANTHER PTHR11938:SF99 71 473 1.8E-96 T 22-04-2016 HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 SUPERFAMILY SSF51971 563 814 4.83E-14 T 22-04-2016 HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 SUPERFAMILY SSF46548 18 172 8.89E-22 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 SUPERFAMILY SSF51971 161 406 4.47E-54 T 22-04-2016 HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 Gene3D G3DSA:3.30.70.20 31 77 2.7E-6 T 22-04-2016 HRM2_RS10945 6045a4cf1a8fc8f9431d62d97bc33d5f 1397 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 24 35 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS10000 9980e5a556fa8c8f601b21ff7616fd08 679 PANTHER PTHR10953:SF145 1 151 4.7E-28 T 22-04-2016 HRM2_RS10000 9980e5a556fa8c8f601b21ff7616fd08 679 Gene3D G3DSA:3.40.109.30 338 408 4.7E-13 T 22-04-2016 HRM2_RS10000 9980e5a556fa8c8f601b21ff7616fd08 679 Gene3D G3DSA:3.40.50.720 23 269 4.6E-35 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS10000 9980e5a556fa8c8f601b21ff7616fd08 679 Pfam PF00899 ThiF family 27 285 5.3E-40 T 22-04-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 HRM2_RS10000 9980e5a556fa8c8f601b21ff7616fd08 679 SUPERFAMILY SSF55469 557 610 9.68E-7 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 HRM2_RS10000 9980e5a556fa8c8f601b21ff7616fd08 679 SUPERFAMILY SSF69572 24 272 1.23E-46 T 22-04-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 HRM2_RS10000 9980e5a556fa8c8f601b21ff7616fd08 679 Gene3D G3DSA:3.40.109.10 469 487 5.0E-15 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 HRM2_RS10000 9980e5a556fa8c8f601b21ff7616fd08 679 Gene3D G3DSA:3.40.109.10 321 337 5.0E-15 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 HRM2_RS10000 9980e5a556fa8c8f601b21ff7616fd08 679 Gene3D G3DSA:3.40.109.10 559 661 5.0E-15 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 HRM2_RS10000 9980e5a556fa8c8f601b21ff7616fd08 679 PANTHER PTHR10953 1 151 4.7E-28 T 22-04-2016 HRM2_RS10000 9980e5a556fa8c8f601b21ff7616fd08 679 SUPERFAMILY SSF55469 321 398 2.49E-10 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 HRM2_RS10000 9980e5a556fa8c8f601b21ff7616fd08 679 SUPERFAMILY SSF55469 429 482 9.68E-7 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 HRM2_RS25660 fd3b41452a6bf63a37eb62c4b0268722 842 Gene3D G3DSA:1.10.287.130 612 683 6.6E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25660 fd3b41452a6bf63a37eb62c4b0268722 842 SUPERFAMILY SSF53850 50 267 1.3E-40 T 22-04-2016 HRM2_RS25660 fd3b41452a6bf63a37eb62c4b0268722 842 SUPERFAMILY SSF55785 475 601 2.09E-8 T 22-04-2016 IPR000014 PAS domain HRM2_RS25660 fd3b41452a6bf63a37eb62c4b0268722 842 Gene3D G3DSA:3.30.450.20 483 601 3.9E-10 T 22-04-2016 HRM2_RS25660 fd3b41452a6bf63a37eb62c4b0268722 842 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 51 264 9.3E-32 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS25660 fd3b41452a6bf63a37eb62c4b0268722 842 Gene3D G3DSA:3.40.190.10 227 265 2.4E-22 T 22-04-2016 HRM2_RS25660 fd3b41452a6bf63a37eb62c4b0268722 842 Gene3D G3DSA:3.40.190.10 45 133 2.4E-22 T 22-04-2016 HRM2_RS25660 fd3b41452a6bf63a37eb62c4b0268722 842 PANTHER PTHR24423 472 839 1.2E-65 T 22-04-2016 HRM2_RS25660 fd3b41452a6bf63a37eb62c4b0268722 842 PANTHER PTHR24423 63 76 1.2E-65 T 22-04-2016 HRM2_RS25660 fd3b41452a6bf63a37eb62c4b0268722 842 SUPERFAMILY SSF55874 692 835 1.44E-33 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25660 fd3b41452a6bf63a37eb62c4b0268722 842 Pfam PF00512 His Kinase A (phospho-acceptor) domain 618 685 8.6E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25660 fd3b41452a6bf63a37eb62c4b0268722 842 SMART SM00062 47 267 3.0E-17 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS25660 fd3b41452a6bf63a37eb62c4b0268722 842 SMART SM00387 729 838 2.9E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25660 fd3b41452a6bf63a37eb62c4b0268722 842 PRINTS PR00344 Bacterial sensor protein C-terminal signature 798 816 2.0E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25660 fd3b41452a6bf63a37eb62c4b0268722 842 PRINTS PR00344 Bacterial sensor protein C-terminal signature 787 797 2.0E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25660 fd3b41452a6bf63a37eb62c4b0268722 842 PRINTS PR00344 Bacterial sensor protein C-terminal signature 822 835 2.0E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25660 fd3b41452a6bf63a37eb62c4b0268722 842 PRINTS PR00344 Bacterial sensor protein C-terminal signature 769 783 2.0E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25660 fd3b41452a6bf63a37eb62c4b0268722 842 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 734 837 1.9E-17 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25660 fd3b41452a6bf63a37eb62c4b0268722 842 Gene3D G3DSA:3.40.190.10 135 222 6.7E-7 T 22-04-2016 HRM2_RS25660 fd3b41452a6bf63a37eb62c4b0268722 842 Gene3D G3DSA:3.30.450.40 331 482 1.4E-10 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS25660 fd3b41452a6bf63a37eb62c4b0268722 842 SUPERFAMILY SSF55781 334 487 3.88E-9 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS25660 fd3b41452a6bf63a37eb62c4b0268722 842 Pfam PF13185 GAF domain 332 475 9.6E-20 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS25660 fd3b41452a6bf63a37eb62c4b0268722 842 SMART SM00388 618 687 1.2E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25660 fd3b41452a6bf63a37eb62c4b0268722 842 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 485 608 1.8E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS25660 fd3b41452a6bf63a37eb62c4b0268722 842 SUPERFAMILY SSF47384 611 686 9.22E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25660 fd3b41452a6bf63a37eb62c4b0268722 842 Gene3D G3DSA:3.30.565.10 688 836 1.1E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS20585 5e5ee72928182be9197fc3e66f97cb23 277 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS20585 5e5ee72928182be9197fc3e66f97cb23 277 Gene3D G3DSA:3.40.50.300 5 232 3.5E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20585 5e5ee72928182be9197fc3e66f97cb23 277 Pfam PF00005 ABC transporter 22 170 3.3E-29 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS20585 5e5ee72928182be9197fc3e66f97cb23 277 PANTHER PTHR24220:SF266 8 260 3.5E-83 T 22-04-2016 HRM2_RS20585 5e5ee72928182be9197fc3e66f97cb23 277 SUPERFAMILY SSF52540 5 232 4.28E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20585 5e5ee72928182be9197fc3e66f97cb23 277 SMART SM00382 31 219 1.7E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS20585 5e5ee72928182be9197fc3e66f97cb23 277 PANTHER PTHR24220 8 260 3.5E-83 T 22-04-2016 HRM2_RS02140 2ad5904111f915d122c4bacb9bd34db1 102 SUPERFAMILY SSF52091 4 99 3.34E-18 T 22-04-2016 IPR002645 STAS domain HRM2_RS02140 2ad5904111f915d122c4bacb9bd34db1 102 Pfam PF01740 STAS domain 6 96 2.2E-11 T 22-04-2016 IPR002645 STAS domain HRM2_RS02140 2ad5904111f915d122c4bacb9bd34db1 102 PANTHER PTHR33495 3 102 5.8E-15 T 22-04-2016 HRM2_RS02140 2ad5904111f915d122c4bacb9bd34db1 102 Gene3D G3DSA:3.30.750.24 3 101 5.9E-23 T 22-04-2016 IPR002645 STAS domain HRM2_RS12015 7ff04bcad9718a5113d65c3f8502a29b 848 Gene3D G3DSA:3.40.50.2000 31 421 2.7E-78 T 22-04-2016 HRM2_RS12015 7ff04bcad9718a5113d65c3f8502a29b 848 Gene3D G3DSA:3.40.50.2000 422 722 1.8E-75 T 22-04-2016 HRM2_RS12015 7ff04bcad9718a5113d65c3f8502a29b 848 PIRSF PIRSF000460 8 794 8.7E-248 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HRM2_RS12015 7ff04bcad9718a5113d65c3f8502a29b 848 Pfam PF11897 Protein of unknown function (DUF3417) 23 125 1.4E-26 T 22-04-2016 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 HRM2_RS12015 7ff04bcad9718a5113d65c3f8502a29b 848 PANTHER PTHR11468:SF9 498 781 7.4E-218 T 22-04-2016 HRM2_RS12015 7ff04bcad9718a5113d65c3f8502a29b 848 PANTHER PTHR11468:SF9 110 480 7.4E-218 T 22-04-2016 HRM2_RS12015 7ff04bcad9718a5113d65c3f8502a29b 848 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 112 714 5.7E-241 T 22-04-2016 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 HRM2_RS12015 7ff04bcad9718a5113d65c3f8502a29b 848 PANTHER PTHR11468 498 781 7.4E-218 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HRM2_RS12015 7ff04bcad9718a5113d65c3f8502a29b 848 PANTHER PTHR11468 110 480 7.4E-218 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HRM2_RS12015 7ff04bcad9718a5113d65c3f8502a29b 848 Pfam PF00343 Carbohydrate phosphorylase 275 625 4.7E-24 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HRM2_RS12015 7ff04bcad9718a5113d65c3f8502a29b 848 Pfam PF00343 Carbohydrate phosphorylase 129 173 2.1E-4 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HRM2_RS12015 7ff04bcad9718a5113d65c3f8502a29b 848 SUPERFAMILY SSF53756 17 736 1.88E-192 T 22-04-2016 HRM2_RS21200 4ae985ded4f153f76b376be45dd9d0c4 316 Pfam PF08349 Protein of unknown function (DUF1722) 191 307 1.9E-44 T 22-04-2016 IPR013560 Domain of unknown function DUF1722 HRM2_RS21200 4ae985ded4f153f76b376be45dd9d0c4 316 Pfam PF04463 Protein of unknown function (DUF523) 7 147 2.0E-37 T 22-04-2016 IPR007553 Domain of unknown function DUF523 HRM2_RS21200 4ae985ded4f153f76b376be45dd9d0c4 316 PIRSF PIRSF037004 1 316 8.1E-125 T 22-04-2016 IPR017087 Uncharacterised conserved protein UCP037004 HRM2_RS21200 4ae985ded4f153f76b376be45dd9d0c4 316 PANTHER PTHR30087 1 316 2.8E-128 T 22-04-2016 HRM2_RS21200 4ae985ded4f153f76b376be45dd9d0c4 316 PANTHER PTHR30087:SF0 1 316 2.8E-128 T 22-04-2016 HRM2_RS19220 f7bc792b6086c6e4ed4bd62cf43d78db 648 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 372 398 5.8E-11 T 22-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 HRM2_RS19220 f7bc792b6086c6e4ed4bd62cf43d78db 648 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 157 181 5.8E-11 T 22-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 HRM2_RS19220 f7bc792b6086c6e4ed4bd62cf43d78db 648 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 222 246 5.8E-11 T 22-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 HRM2_RS19220 f7bc792b6086c6e4ed4bd62cf43d78db 648 PANTHER PTHR22773 1 585 3.1E-172 T 22-04-2016 HRM2_RS19220 f7bc792b6086c6e4ed4bd62cf43d78db 648 Pfam PF00361 Proton-conducting membrane transporter 124 400 3.9E-57 T 22-04-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: REACT_6305 HRM2_RS19220 f7bc792b6086c6e4ed4bd62cf43d78db 648 PANTHER PTHR22773:SF91 1 585 3.1E-172 T 22-04-2016 HRM2_RS11105 770affb6a8999b0f5612cc1096491409 893 Gene3D G3DSA:2.40.160.50 525 893 1.8E-23 T 22-04-2016 HRM2_RS11105 770affb6a8999b0f5612cc1096491409 893 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 171 893 1.7E-181 T 22-04-2016 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 HRM2_RS11105 770affb6a8999b0f5612cc1096491409 893 PANTHER PTHR12815 151 893 4.7E-162 T 22-04-2016 HRM2_RS11105 770affb6a8999b0f5612cc1096491409 893 PIRSF PIRSF006076 128 893 7.0E-206 T 22-04-2016 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 HRM2_RS11105 770affb6a8999b0f5612cc1096491409 893 PANTHER PTHR12815:SF11 151 893 4.7E-162 T 22-04-2016 HRM2_RS11105 770affb6a8999b0f5612cc1096491409 893 Pfam PF07244 Surface antigen variable number repeat 322 407 3.2E-13 T 22-04-2016 IPR010827 Surface antigen variable number GO:0019867 HRM2_RS11105 770affb6a8999b0f5612cc1096491409 893 Pfam PF07244 Surface antigen variable number repeat 171 240 2.3E-12 T 22-04-2016 IPR010827 Surface antigen variable number GO:0019867 HRM2_RS11105 770affb6a8999b0f5612cc1096491409 893 Pfam PF07244 Surface antigen variable number repeat 242 318 9.4E-12 T 22-04-2016 IPR010827 Surface antigen variable number GO:0019867 HRM2_RS11105 770affb6a8999b0f5612cc1096491409 893 Pfam PF07244 Surface antigen variable number repeat 491 564 2.1E-12 T 22-04-2016 IPR010827 Surface antigen variable number GO:0019867 HRM2_RS11105 770affb6a8999b0f5612cc1096491409 893 Pfam PF07244 Surface antigen variable number repeat 410 487 4.0E-10 T 22-04-2016 IPR010827 Surface antigen variable number GO:0019867 HRM2_RS11105 770affb6a8999b0f5612cc1096491409 893 Pfam PF01103 Surface antigen 591 893 3.0E-55 T 22-04-2016 IPR000184 Bacterial surface antigen (D15) GO:0019867 HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 Pfam PF00122 E1-E2 ATPase 283 504 1.1E-48 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 Pfam PF00702 haloacid dehalogenase-like hydrolase 510 724 2.8E-24 T 22-04-2016 HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 SUPERFAMILY SSF55008 98 169 4.97E-18 T 22-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 SUPERFAMILY SSF56784 511 580 1.91E-34 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 SUPERFAMILY SSF56784 626 811 1.91E-34 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 657 667 1.71E-16 T 22-04-2016 HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 363 377 1.71E-16 T 22-04-2016 HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 513 527 1.71E-16 T 22-04-2016 HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 712 731 1.71E-16 T 22-04-2016 HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 Pfam PF00403 Heavy-metal-associated domain 105 164 3.4E-9 T 22-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 Gene3D G3DSA:3.40.1110.10 532 637 4.7E-4 T 22-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 SUPERFAMILY SSF81653 328 411 1.96E-16 T 22-04-2016 HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 PANTHER PTHR24093 102 814 2.4E-153 T 22-04-2016 HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 250 814 6.7E-132 T 22-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 Gene3D G3DSA:2.70.150.10 252 413 1.1E-17 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 232 814 5.4E-123 T 22-04-2016 HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 515 521 - T 22-04-2016 IPR018303 P-type ATPase, phosphorylation site HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 284 800 5.6E-63 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 Gene3D G3DSA:3.40.50.1000 638 780 5.4E-31 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 Gene3D G3DSA:3.40.50.1000 486 529 5.4E-31 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 Gene3D G3DSA:3.30.70.100 102 166 7.9E-17 T 22-04-2016 HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 PANTHER PTHR24093:SF50 102 814 2.4E-153 T 22-04-2016 HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 PRINTS PR00943 Copper-transporting ATPase signature 146 166 6.74E-11 T 22-04-2016 HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 PRINTS PR00943 Copper-transporting ATPase signature 496 511 6.74E-11 T 22-04-2016 HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 PRINTS PR00943 Copper-transporting ATPase signature 689 706 6.74E-11 T 22-04-2016 HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 PRINTS PR00943 Copper-transporting ATPase signature 281 300 6.74E-11 T 22-04-2016 HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 PRINTS PR00943 Copper-transporting ATPase signature 436 450 6.74E-11 T 22-04-2016 HRM2_RS07490 6ba5f74351d240bc406dce547cf0400e 825 SUPERFAMILY SSF81665 414 507 5.62E-10 T 22-04-2016 HRM2_RS02785 226d6dd313797963ee668bed8aa0f4b1 538 Gene3D G3DSA:3.30.70.270 117 279 1.8E-42 T 22-04-2016 HRM2_RS02785 226d6dd313797963ee668bed8aa0f4b1 538 Pfam PF00990 Diguanylate cyclase, GGDEF domain 115 268 3.3E-40 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS02785 226d6dd313797963ee668bed8aa0f4b1 538 PANTHER PTHR33121:SF13 238 535 2.0E-82 T 22-04-2016 HRM2_RS02785 226d6dd313797963ee668bed8aa0f4b1 538 PANTHER PTHR33121:SF13 10 22 2.0E-82 T 22-04-2016 HRM2_RS02785 226d6dd313797963ee668bed8aa0f4b1 538 PANTHER PTHR33121 238 535 2.0E-82 T 22-04-2016 HRM2_RS02785 226d6dd313797963ee668bed8aa0f4b1 538 PANTHER PTHR33121 10 22 2.0E-82 T 22-04-2016 HRM2_RS02785 226d6dd313797963ee668bed8aa0f4b1 538 SMART SM00267 103 275 3.5E-38 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS02785 226d6dd313797963ee668bed8aa0f4b1 538 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 113 271 5.1E-30 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS02785 226d6dd313797963ee668bed8aa0f4b1 538 Gene3D G3DSA:3.20.20.450 290 537 1.4E-96 T 22-04-2016 IPR001633 EAL domain HRM2_RS02785 226d6dd313797963ee668bed8aa0f4b1 538 SUPERFAMILY SSF55073 121 270 3.3E-39 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS02785 226d6dd313797963ee668bed8aa0f4b1 538 Pfam PF00563 EAL domain 292 525 2.9E-76 T 22-04-2016 IPR001633 EAL domain HRM2_RS02785 226d6dd313797963ee668bed8aa0f4b1 538 SUPERFAMILY SSF141868 291 536 1.31E-92 T 22-04-2016 IPR001633 EAL domain HRM2_RS02785 226d6dd313797963ee668bed8aa0f4b1 538 SMART SM00052 285 530 4.3E-109 T 22-04-2016 IPR001633 EAL domain HRM2_RS12710 2771913be9f4360871d0d0412c3668c9 437 Gene3D G3DSA:2.40.160.10 140 309 2.1E-5 T 22-04-2016 IPR023614 Porin domain HRM2_RS12710 2771913be9f4360871d0d0412c3668c9 437 Pfam PF10082 Putative beta-barrel porin 2 208 435 2.1E-25 T 22-04-2016 IPR018759 Putative beta-barrel porin 2 HRM2_RS12710 2771913be9f4360871d0d0412c3668c9 437 SUPERFAMILY SSF56935 136 317 1.72E-9 T 22-04-2016 HRM2_RS09735 1e7be821aeb01f399ac2b1519925f85e 282 Pfam PF03618 Kinase/pyrophosphorylase 13 268 1.2E-74 T 22-04-2016 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 HRM2_RS09735 1e7be821aeb01f399ac2b1519925f85e 282 PANTHER PTHR31756:SF3 13 276 1.7E-70 T 22-04-2016 HRM2_RS09735 1e7be821aeb01f399ac2b1519925f85e 282 PANTHER PTHR31756 13 276 1.7E-70 T 22-04-2016 HRM2_RS08695 61ea4f4896682c416544b333bd69f614 467 Gene3D G3DSA:3.30.450.20 31 141 3.0E-10 T 22-04-2016 HRM2_RS08695 61ea4f4896682c416544b333bd69f614 467 PANTHER PTHR24423:SF383 316 326 3.9E-20 T 22-04-2016 HRM2_RS08695 61ea4f4896682c416544b333bd69f614 467 PANTHER PTHR24423:SF383 21 289 3.9E-20 T 22-04-2016 HRM2_RS08695 61ea4f4896682c416544b333bd69f614 467 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 291 453 2.9E-38 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS08695 61ea4f4896682c416544b333bd69f614 467 SUPERFAMILY SSF55073 298 452 5.96E-37 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS08695 61ea4f4896682c416544b333bd69f614 467 SMART SM00086 107 149 7.3 T 22-04-2016 IPR001610 PAC motif HRM2_RS08695 61ea4f4896682c416544b333bd69f614 467 SMART SM00086 234 275 0.47 T 22-04-2016 IPR001610 PAC motif HRM2_RS08695 61ea4f4896682c416544b333bd69f614 467 Pfam PF00990 Diguanylate cyclase, GGDEF domain 293 450 3.5E-34 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS08695 61ea4f4896682c416544b333bd69f614 467 PANTHER PTHR24423 316 326 3.9E-20 T 22-04-2016 HRM2_RS08695 61ea4f4896682c416544b333bd69f614 467 PANTHER PTHR24423 21 289 3.9E-20 T 22-04-2016 HRM2_RS08695 61ea4f4896682c416544b333bd69f614 467 SUPERFAMILY SSF55785 31 141 7.15E-11 T 22-04-2016 IPR000014 PAS domain HRM2_RS08695 61ea4f4896682c416544b333bd69f614 467 SUPERFAMILY SSF55785 147 271 3.84E-17 T 22-04-2016 IPR000014 PAS domain HRM2_RS08695 61ea4f4896682c416544b333bd69f614 467 Gene3D G3DSA:3.30.450.20 147 271 2.4E-17 T 22-04-2016 HRM2_RS08695 61ea4f4896682c416544b333bd69f614 467 SMART SM00091 42 107 0.0032 T 22-04-2016 IPR000014 PAS domain HRM2_RS08695 61ea4f4896682c416544b333bd69f614 467 SMART SM00091 161 231 0.86 T 22-04-2016 IPR000014 PAS domain HRM2_RS08695 61ea4f4896682c416544b333bd69f614 467 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 158 281 6.3E-12 T 22-04-2016 IPR000014 PAS domain HRM2_RS08695 61ea4f4896682c416544b333bd69f614 467 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 39 156 3.3E-9 T 22-04-2016 IPR000014 PAS domain HRM2_RS08695 61ea4f4896682c416544b333bd69f614 467 SMART SM00267 282 455 7.0E-42 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS08695 61ea4f4896682c416544b333bd69f614 467 Pfam PF13426 PAS domain 53 148 2.7E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS08695 61ea4f4896682c416544b333bd69f614 467 Pfam PF13426 PAS domain 173 274 7.2E-9 T 22-04-2016 IPR000014 PAS domain HRM2_RS08695 61ea4f4896682c416544b333bd69f614 467 Gene3D G3DSA:3.30.70.270 295 453 5.5E-41 T 22-04-2016 HRM2_RS00005 c803708c667049d5a592716033888cf3 371 Gene3D G3DSA:3.10.150.10 127 253 1.3E-19 T 22-04-2016 HRM2_RS00005 c803708c667049d5a592716033888cf3 371 Gene3D G3DSA:3.10.150.10 1 119 1.8E-17 T 22-04-2016 HRM2_RS00005 c803708c667049d5a592716033888cf3 371 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 250 369 1.7E-22 T 22-04-2016 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS00005 c803708c667049d5a592716033888cf3 371 SUPERFAMILY SSF55979 1 118 4.29E-18 T 22-04-2016 HRM2_RS00005 c803708c667049d5a592716033888cf3 371 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 118 5.4E-19 T 22-04-2016 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS00005 c803708c667049d5a592716033888cf3 371 SUPERFAMILY SSF55979 128 252 4.96E-12 T 22-04-2016 HRM2_RS00005 c803708c667049d5a592716033888cf3 371 SUPERFAMILY SSF55979 250 369 1.81E-27 T 22-04-2016 HRM2_RS00005 c803708c667049d5a592716033888cf3 371 PANTHER PTHR30478 2 371 1.5E-79 T 22-04-2016 HRM2_RS00005 c803708c667049d5a592716033888cf3 371 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 370 6.9E-76 T 22-04-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS00005 c803708c667049d5a592716033888cf3 371 Pfam PF02767 DNA polymerase III beta subunit, central domain 129 248 8.4E-16 T 22-04-2016 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS00005 c803708c667049d5a592716033888cf3 371 SMART SM00480 17 367 1.3E-60 T 22-04-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS00005 c803708c667049d5a592716033888cf3 371 PIRSF PIRSF000804 1 371 2.6E-87 T 22-04-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS00005 c803708c667049d5a592716033888cf3 371 Gene3D G3DSA:3.10.150.10 256 370 6.4E-28 T 22-04-2016 HRM2_RS01865 7647b6586776dfcb02de146baf73431e 113 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 71 9.9E-9 T 22-04-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain HRM2_RS01865 7647b6586776dfcb02de146baf73431e 113 SUPERFAMILY SSF54909 1 71 1.11E-14 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel HRM2_RS01865 7647b6586776dfcb02de146baf73431e 113 Gene3D G3DSA:3.30.70.900 1 90 5.1E-15 T 22-04-2016 HRM2_RS24345 bef6855dfd491f41554332008538e27d 319 PANTHER PTHR24220:SF535 6 319 7.7E-140 T 22-04-2016 HRM2_RS24345 bef6855dfd491f41554332008538e27d 319 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 318 1.1E-27 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HRM2_RS24345 bef6855dfd491f41554332008538e27d 319 SMART SM00382 33 239 1.1E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS24345 bef6855dfd491f41554332008538e27d 319 Gene3D G3DSA:3.40.50.300 4 256 2.7E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24345 bef6855dfd491f41554332008538e27d 319 SUPERFAMILY SSF52540 33 310 2.13E-63 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24345 bef6855dfd491f41554332008538e27d 319 Pfam PF00005 ABC transporter 25 182 2.1E-26 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS24345 bef6855dfd491f41554332008538e27d 319 PANTHER PTHR24220 6 319 7.7E-140 T 22-04-2016 HRM2_RS24345 bef6855dfd491f41554332008538e27d 319 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 298 1.1E-17 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HRM2_RS24345 bef6855dfd491f41554332008538e27d 319 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS01880 cf0f4a1aec0ec1e98630abd1bea6a433 423 TIGRFAM TIGR00238 TIGR00238: KamA family protein 4 329 4.1E-106 T 22-04-2016 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase HRM2_RS01880 cf0f4a1aec0ec1e98630abd1bea6a433 423 TIGRFAM TIGR03820 lys_2_3_AblA: lysine-2,3-aminomutase 5 420 8.7E-235 T 22-04-2016 IPR022459 Lysine-2,3-aminomutase KEGG: 00310+5.4.3.2 HRM2_RS01880 cf0f4a1aec0ec1e98630abd1bea6a433 423 Gene3D G3DSA:3.20.20.70 100 314 8.5E-17 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS01880 cf0f4a1aec0ec1e98630abd1bea6a433 423 PIRSF PIRSF004911 1 386 2.4E-153 T 22-04-2016 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase HRM2_RS01880 cf0f4a1aec0ec1e98630abd1bea6a433 423 SUPERFAMILY SSF102114 101 344 4.71E-31 T 22-04-2016 HRM2_RS01880 cf0f4a1aec0ec1e98630abd1bea6a433 423 PANTHER PTHR30538:SF1 4 378 4.3E-163 T 22-04-2016 HRM2_RS01880 cf0f4a1aec0ec1e98630abd1bea6a433 423 PANTHER PTHR30538 4 378 4.3E-163 T 22-04-2016 HRM2_RS01880 cf0f4a1aec0ec1e98630abd1bea6a433 423 Pfam PF04055 Radical SAM superfamily 117 264 4.7E-10 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS01880 cf0f4a1aec0ec1e98630abd1bea6a433 423 Pfam PF12544 Lysine-2,3-aminomutase 308 422 5.3E-42 T 22-04-2016 IPR025895 Lysine-2,3-aminomutase, C-terminal domain HRM2_RS01770 c751d21848ed4eeffbaab88b1a04d4fc 549 PANTHER PTHR24423 9 543 5.8E-156 T 22-04-2016 HRM2_RS01770 c751d21848ed4eeffbaab88b1a04d4fc 549 PANTHER PTHR24423:SF544 9 543 5.8E-156 T 22-04-2016 HRM2_RS01770 c751d21848ed4eeffbaab88b1a04d4fc 549 Gene3D G3DSA:3.40.50.2300 420 543 1.2E-29 T 22-04-2016 HRM2_RS01770 c751d21848ed4eeffbaab88b1a04d4fc 549 Gene3D G3DSA:3.30.450.20 37 177 4.0E-25 T 22-04-2016 HRM2_RS01770 c751d21848ed4eeffbaab88b1a04d4fc 549 Pfam PF13426 PAS domain 53 149 2.3E-13 T 22-04-2016 IPR000014 PAS domain HRM2_RS01770 c751d21848ed4eeffbaab88b1a04d4fc 549 PRINTS PR00344 Bacterial sensor protein C-terminal signature 349 359 6.2E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS01770 c751d21848ed4eeffbaab88b1a04d4fc 549 PRINTS PR00344 Bacterial sensor protein C-terminal signature 331 345 6.2E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS01770 c751d21848ed4eeffbaab88b1a04d4fc 549 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 380 6.2E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS01770 c751d21848ed4eeffbaab88b1a04d4fc 549 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 399 6.2E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS01770 c751d21848ed4eeffbaab88b1a04d4fc 549 SMART SM00086 108 150 6.1E-5 T 22-04-2016 IPR001610 PAC motif HRM2_RS01770 c751d21848ed4eeffbaab88b1a04d4fc 549 SUPERFAMILY SSF52172 421 541 1.99E-30 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS01770 c751d21848ed4eeffbaab88b1a04d4fc 549 SMART SM00091 36 102 8.4E-12 T 22-04-2016 IPR000014 PAS domain HRM2_RS01770 c751d21848ed4eeffbaab88b1a04d4fc 549 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 280 400 6.5E-23 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS01770 c751d21848ed4eeffbaab88b1a04d4fc 549 SMART SM00387 279 402 3.0E-32 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS01770 c751d21848ed4eeffbaab88b1a04d4fc 549 SUPERFAMILY SSF47384 164 239 1.9E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS01770 c751d21848ed4eeffbaab88b1a04d4fc 549 Pfam PF00072 Response regulator receiver domain 424 534 3.4E-20 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS01770 c751d21848ed4eeffbaab88b1a04d4fc 549 Pfam PF00512 His Kinase A (phospho-acceptor) domain 176 238 1.4E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS01770 c751d21848ed4eeffbaab88b1a04d4fc 549 SMART SM00448 422 535 1.0E-23 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS01770 c751d21848ed4eeffbaab88b1a04d4fc 549 Gene3D G3DSA:3.30.565.10 224 402 1.8E-40 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS01770 c751d21848ed4eeffbaab88b1a04d4fc 549 SMART SM00388 172 238 2.6E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS01770 c751d21848ed4eeffbaab88b1a04d4fc 549 SUPERFAMILY SSF55785 41 152 5.39E-25 T 22-04-2016 IPR000014 PAS domain HRM2_RS01770 c751d21848ed4eeffbaab88b1a04d4fc 549 Gene3D G3DSA:1.10.287.130 178 223 3.3E-5 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS01770 c751d21848ed4eeffbaab88b1a04d4fc 549 SUPERFAMILY SSF55874 228 400 7.6E-39 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS01770 c751d21848ed4eeffbaab88b1a04d4fc 549 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 33 156 2.4E-20 T 22-04-2016 IPR000014 PAS domain HRM2_RS23790 e9b6cb7eb540fb6038851ca6f633c1d7 327 PANTHER PTHR12001:SF47 7 327 4.9E-94 T 22-04-2016 HRM2_RS23790 e9b6cb7eb540fb6038851ca6f633c1d7 327 SUPERFAMILY SSF48576 8 326 3.52E-84 T 22-04-2016 IPR008949 Isoprenoid synthase domain HRM2_RS23790 e9b6cb7eb540fb6038851ca6f633c1d7 327 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 206 218 - T 22-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 HRM2_RS23790 e9b6cb7eb540fb6038851ca6f633c1d7 327 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 84 98 - T 22-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 HRM2_RS23790 e9b6cb7eb540fb6038851ca6f633c1d7 327 Pfam PF00348 Polyprenyl synthetase 34 274 4.8E-64 T 22-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 HRM2_RS23790 e9b6cb7eb540fb6038851ca6f633c1d7 327 Gene3D G3DSA:1.10.600.10 8 326 6.5E-91 T 22-04-2016 IPR008949 Isoprenoid synthase domain HRM2_RS23790 e9b6cb7eb540fb6038851ca6f633c1d7 327 PANTHER PTHR12001 7 327 4.9E-94 T 22-04-2016 IPR017446 Polyprenyl synthetase-related HRM2_RS20915 49aaa65268cf94222e2185112bdfa912 286 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 243 7.3E-27 T 22-04-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain HRM2_RS20915 49aaa65268cf94222e2185112bdfa912 286 SUPERFAMILY SSF52540 141 263 1.26E-28 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20915 49aaa65268cf94222e2185112bdfa912 286 SUPERFAMILY SSF52540 1 68 1.26E-28 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20915 49aaa65268cf94222e2185112bdfa912 286 PANTHER PTHR13696:SF64 1 278 2.5E-56 T 22-04-2016 HRM2_RS20915 49aaa65268cf94222e2185112bdfa912 286 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 97 108 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS20915 49aaa65268cf94222e2185112bdfa912 286 PANTHER PTHR13696 1 278 2.5E-56 T 22-04-2016 HRM2_RS20915 49aaa65268cf94222e2185112bdfa912 286 SUPERFAMILY SSF54862 53 117 1.37E-17 T 22-04-2016 HRM2_RS20915 49aaa65268cf94222e2185112bdfa912 286 Gene3D G3DSA:3.30.70.20 55 118 1.3E-13 T 22-04-2016 HRM2_RS20915 49aaa65268cf94222e2185112bdfa912 286 Gene3D G3DSA:3.40.50.300 140 280 1.1E-29 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20915 49aaa65268cf94222e2185112bdfa912 286 Gene3D G3DSA:3.40.50.300 1 51 1.1E-29 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20915 49aaa65268cf94222e2185112bdfa912 286 Pfam PF00037 4Fe-4S binding domain 61 84 1.0E-6 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS20915 49aaa65268cf94222e2185112bdfa912 286 Pfam PF00037 4Fe-4S binding domain 94 113 2.9E-5 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS21575 71ae55abe4828f489d4838b6f306a134 324 PANTHER PTHR24093 2 323 7.2E-116 T 22-04-2016 HRM2_RS21575 71ae55abe4828f489d4838b6f306a134 324 PANTHER PTHR24093:SF329 2 323 7.2E-116 T 22-04-2016 HRM2_RS21575 71ae55abe4828f489d4838b6f306a134 324 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 233 254 1.1E-18 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 HRM2_RS21575 71ae55abe4828f489d4838b6f306a134 324 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 65 81 1.1E-18 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 HRM2_RS21575 71ae55abe4828f489d4838b6f306a134 324 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 37 53 1.1E-18 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 HRM2_RS21575 71ae55abe4828f489d4838b6f306a134 324 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 97 122 1.1E-18 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 HRM2_RS21575 71ae55abe4828f489d4838b6f306a134 324 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 35 153 6.8E-36 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 HRM2_RS21575 71ae55abe4828f489d4838b6f306a134 324 Pfam PF00689 Cation transporting ATPase, C-terminus 150 317 3.9E-47 T 22-04-2016 IPR006068 Cation-transporting P-type ATPase, C-terminal HRM2_RS21575 71ae55abe4828f489d4838b6f306a134 324 SUPERFAMILY SSF56784 2 170 2.6E-40 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS21575 71ae55abe4828f489d4838b6f306a134 324 Pfam PF00702 haloacid dehalogenase-like hydrolase 27 79 3.5E-11 T 22-04-2016 HRM2_RS21575 71ae55abe4828f489d4838b6f306a134 324 SUPERFAMILY SSF81665 115 319 1.96E-58 T 22-04-2016 HRM2_RS21575 71ae55abe4828f489d4838b6f306a134 324 Gene3D G3DSA:1.20.1110.10 34 318 1.6E-101 T 22-04-2016 IPR023298 P-type ATPase, transmembrane domain HRM2_RS19390 14f911b84bed86f48416560bbcd0cf26 257 PIRSF PIRSF001430 3 257 4.3E-43 T 22-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS19390 14f911b84bed86f48416560bbcd0cf26 257 Gene3D G3DSA:3.30.70.660 110 255 1.5E-23 T 22-04-2016 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS19390 14f911b84bed86f48416560bbcd0cf26 257 SUPERFAMILY SSF55120 2 256 4.75E-50 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS19390 14f911b84bed86f48416560bbcd0cf26 257 PANTHER PTHR11142 3 256 1.2E-44 T 22-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS19390 14f911b84bed86f48416560bbcd0cf26 257 Gene3D G3DSA:3.30.70.580 4 103 6.6E-22 T 22-04-2016 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS19390 14f911b84bed86f48416560bbcd0cf26 257 Pfam PF01416 tRNA pseudouridine synthase 149 256 1.0E-11 T 22-04-2016 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 PANTHER PTHR11938 292 689 7.8E-98 T 22-04-2016 HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 Gene3D G3DSA:3.40.50.720 383 614 2.9E-51 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 Gene3D G3DSA:3.30.70.20 1067 1126 1.7E-17 T 22-04-2016 HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 Gene3D G3DSA:3.30.70.20 234 264 1.7E-17 T 22-04-2016 HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 SUPERFAMILY SSF51971 380 624 9.42E-62 T 22-04-2016 HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 PRINTS PR00419 Adrenodoxin reductase family signature 382 404 1.9E-20 T 22-04-2016 HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 PRINTS PR00419 Adrenodoxin reductase family signature 405 418 1.9E-20 T 22-04-2016 HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 PRINTS PR00419 Adrenodoxin reductase family signature 548 561 1.9E-20 T 22-04-2016 HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 PRINTS PR00419 Adrenodoxin reductase family signature 514 528 1.9E-20 T 22-04-2016 HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 1101 1112 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 243 254 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 772 783 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 1070 1081 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 Gene3D G3DSA:3.50.50.60 622 687 2.0E-4 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 Gene3D G3DSA:3.30.70.20 776 799 5.4E-11 T 22-04-2016 HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 SUPERFAMILY SSF51905 141 232 2.05E-11 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 290 365 6.1E-16 T 22-04-2016 IPR028261 Dihydroprymidine dehydrogenase domain II HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 SUPERFAMILY SSF46548 290 391 4.71E-17 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 Pfam PF13187 4Fe-4S dicluster domain 1070 1115 7.8E-7 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 SUPERFAMILY SSF46548 730 789 1.2E-9 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 143 233 1.3E-7 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 880 1043 2.8E-7 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 382 677 6.7E-33 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 SUPERFAMILY SSF51905 777 1046 2.59E-8 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 SUPERFAMILY SSF51971 599 682 1.18E-7 T 22-04-2016 HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 Gene3D G3DSA:1.10.1060.10 290 382 1.4E-23 T 22-04-2016 HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 Gene3D G3DSA:1.10.1060.10 721 775 1.8E-13 T 22-04-2016 HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 Pfam PF00037 4Fe-4S binding domain 242 256 1.1E-4 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 PANTHER PTHR11938:SF99 292 689 7.8E-98 T 22-04-2016 HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 Gene3D G3DSA:3.50.50.60 800 838 1.5E-10 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 Gene3D G3DSA:3.50.50.60 1002 1048 1.5E-10 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 Gene3D G3DSA:3.50.50.60 144 233 4.1E-25 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 SUPERFAMILY SSF54862 240 306 3.99E-17 T 22-04-2016 HRM2_RS11270 0487673ca5e70db0ad2166aef4ac6624 1140 SUPERFAMILY SSF54862 1035 1125 3.99E-17 T 22-04-2016 HRM2_RS19800 b632972cb1aefca35160b481d2a3f955 476 PANTHER PTHR30203 6 466 2.5E-157 T 22-04-2016 HRM2_RS19800 b632972cb1aefca35160b481d2a3f955 476 Gene3D G3DSA:1.20.1600.10 353 466 5.1E-88 T 22-04-2016 HRM2_RS19800 b632972cb1aefca35160b481d2a3f955 476 Gene3D G3DSA:1.20.1600.10 57 93 5.1E-88 T 22-04-2016 HRM2_RS19800 b632972cb1aefca35160b481d2a3f955 476 Gene3D G3DSA:1.20.1600.10 145 316 5.1E-88 T 22-04-2016 HRM2_RS19800 b632972cb1aefca35160b481d2a3f955 476 Pfam PF02321 Outer membrane efflux protein 67 257 2.1E-23 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS19800 b632972cb1aefca35160b481d2a3f955 476 Pfam PF02321 Outer membrane efflux protein 285 464 1.5E-17 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS19800 b632972cb1aefca35160b481d2a3f955 476 Gene3D G3DSA:2.20.200.10 103 144 3.1E-19 T 22-04-2016 HRM2_RS19800 b632972cb1aefca35160b481d2a3f955 476 Gene3D G3DSA:2.20.200.10 317 352 3.1E-19 T 22-04-2016 HRM2_RS19800 b632972cb1aefca35160b481d2a3f955 476 PANTHER PTHR30203:SF15 6 466 2.5E-157 T 22-04-2016 HRM2_RS19800 b632972cb1aefca35160b481d2a3f955 476 SUPERFAMILY SSF56954 58 467 7.59E-103 T 22-04-2016 HRM2_RS19800 b632972cb1aefca35160b481d2a3f955 476 SUPERFAMILY SSF56954 2 28 7.59E-103 T 22-04-2016 HRM2_RS19800 b632972cb1aefca35160b481d2a3f955 476 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 10 466 2.6E-113 T 22-04-2016 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 HRM2_RS06245 740b9874da1cfc6cc757f9d31c0db49c 519 Pfam PF11066 Protein of unknown function (DUF2867) 354 487 5.5E-18 T 22-04-2016 IPR021295 Protein of unknown function DUF2867 HRM2_RS06245 740b9874da1cfc6cc757f9d31c0db49c 519 PANTHER PTHR10366:SF401 275 314 1.8E-80 T 22-04-2016 HRM2_RS06245 740b9874da1cfc6cc757f9d31c0db49c 519 PANTHER PTHR10366:SF401 14 254 1.8E-80 T 22-04-2016 HRM2_RS06245 740b9874da1cfc6cc757f9d31c0db49c 519 SUPERFAMILY SSF51735 13 267 5.91E-41 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS06245 740b9874da1cfc6cc757f9d31c0db49c 519 PANTHER PTHR10366 275 314 1.8E-80 T 22-04-2016 HRM2_RS06245 740b9874da1cfc6cc757f9d31c0db49c 519 PANTHER PTHR10366 14 254 1.8E-80 T 22-04-2016 HRM2_RS06245 740b9874da1cfc6cc757f9d31c0db49c 519 Pfam PF13460 NAD(P)H-binding 19 163 5.1E-14 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS06245 740b9874da1cfc6cc757f9d31c0db49c 519 Gene3D G3DSA:3.40.50.720 13 244 3.7E-34 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS22945 d502d30600332d12bb11d7c3101ae983 386 PANTHER PTHR30085 245 386 2.8E-114 T 22-04-2016 HRM2_RS22945 d502d30600332d12bb11d7c3101ae983 386 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 380 9.2E-11 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS22945 d502d30600332d12bb11d7c3101ae983 386 SUPERFAMILY SSF161098 180 367 3.4E-26 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS22945 d502d30600332d12bb11d7c3101ae983 386 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 77 139 2.8E-15 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HRM2_RS22945 d502d30600332d12bb11d7c3101ae983 386 PANTHER PTHR30085 7 166 2.8E-114 T 22-04-2016 HRM2_RS22945 d502d30600332d12bb11d7c3101ae983 386 PANTHER PTHR30085:SF1 245 386 2.8E-114 T 22-04-2016 HRM2_RS22945 d502d30600332d12bb11d7c3101ae983 386 Gene3D G3DSA:1.10.3720.10 77 142 1.1E-12 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS22945 d502d30600332d12bb11d7c3101ae983 386 Gene3D G3DSA:1.10.3720.10 179 381 7.5E-34 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS22945 d502d30600332d12bb11d7c3101ae983 386 PANTHER PTHR30085:SF1 7 166 2.8E-114 T 22-04-2016 HRM2_RS22945 d502d30600332d12bb11d7c3101ae983 386 SUPERFAMILY SSF161098 78 142 2.75E-11 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS19810 49d1fc69c868aae4084e697e74025940 460 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 70 339 1.9E-12 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain HRM2_RS19810 49d1fc69c868aae4084e697e74025940 460 SUPERFAMILY SSF111369 201 346 1.83E-49 T 22-04-2016 HRM2_RS19810 49d1fc69c868aae4084e697e74025940 460 PANTHER PTHR30158 1 115 1.6E-143 T 22-04-2016 HRM2_RS19810 49d1fc69c868aae4084e697e74025940 460 PANTHER PTHR30158 137 174 1.6E-143 T 22-04-2016 HRM2_RS19810 49d1fc69c868aae4084e697e74025940 460 PANTHER PTHR30158 196 421 1.6E-143 T 22-04-2016 HRM2_RS19810 49d1fc69c868aae4084e697e74025940 460 PANTHER PTHR30158:SF3 1 115 1.6E-143 T 22-04-2016 HRM2_RS19810 49d1fc69c868aae4084e697e74025940 460 PANTHER PTHR30158:SF3 137 174 1.6E-143 T 22-04-2016 HRM2_RS19810 49d1fc69c868aae4084e697e74025940 460 PANTHER PTHR30158:SF3 196 421 1.6E-143 T 22-04-2016 HRM2_RS19810 49d1fc69c868aae4084e697e74025940 460 SUPERFAMILY SSF111369 59 140 6.28E-22 T 22-04-2016 HRM2_RS19810 49d1fc69c868aae4084e697e74025940 460 SUPERFAMILY SSF111369 138 172 1.83E-49 T 22-04-2016 HRM2_RS19810 49d1fc69c868aae4084e697e74025940 460 Gene3D G3DSA:2.40.50.100 222 257 1.7E-25 T 22-04-2016 HRM2_RS19810 49d1fc69c868aae4084e697e74025940 460 Gene3D G3DSA:2.40.50.100 73 105 1.7E-25 T 22-04-2016 HRM2_RS19810 49d1fc69c868aae4084e697e74025940 460 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 186 421 1.4E-52 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 HRM2_RS11140 1e3c13328880c9372049cd457263eaae 371 SUPERFAMILY SSF48600 17 103 2.01E-18 T 22-04-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 HRM2_RS11140 1e3c13328880c9372049cd457263eaae 371 PANTHER PTHR21022 17 369 9.5E-114 T 22-04-2016 HRM2_RS11140 1e3c13328880c9372049cd457263eaae 371 Gene3D G3DSA:1.20.59.10 15 98 2.2E-17 T 22-04-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 HRM2_RS11140 1e3c13328880c9372049cd457263eaae 371 SMART SM00830 22 101 1.0E-19 T 22-04-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 HRM2_RS11140 1e3c13328880c9372049cd457263eaae 371 SUPERFAMILY SSF55021 272 366 1.88E-25 T 22-04-2016 HRM2_RS11140 1e3c13328880c9372049cd457263eaae 371 Pfam PF01817 Chorismate mutase type II 22 98 4.2E-17 T 22-04-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 HRM2_RS11140 1e3c13328880c9372049cd457263eaae 371 SUPERFAMILY SSF53850 102 284 9.12E-59 T 22-04-2016 HRM2_RS11140 1e3c13328880c9372049cd457263eaae 371 Gene3D G3DSA:3.40.190.10 99 188 2.0E-27 T 22-04-2016 HRM2_RS11140 1e3c13328880c9372049cd457263eaae 371 PIRSF PIRSF001500 12 370 1.2E-118 T 22-04-2016 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432|UniPathway: UPA00121 HRM2_RS11140 1e3c13328880c9372049cd457263eaae 371 Gene3D G3DSA:3.40.190.10 189 264 2.0E-28 T 22-04-2016 HRM2_RS11140 1e3c13328880c9372049cd457263eaae 371 Pfam PF00800 Prephenate dehydratase 103 278 1.4E-60 T 22-04-2016 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432|UniPathway: UPA00121 HRM2_RS11140 1e3c13328880c9372049cd457263eaae 371 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 253 275 - T 22-04-2016 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432|UniPathway: UPA00121 HRM2_RS11140 1e3c13328880c9372049cd457263eaae 371 Gene3D G3DSA:3.30.70.260 282 367 3.8E-28 T 22-04-2016 HRM2_RS11140 1e3c13328880c9372049cd457263eaae 371 PANTHER PTHR21022:SF0 17 369 9.5E-114 T 22-04-2016 HRM2_RS24205 034272e7c0d61b151665063f1697853a 427 PANTHER PTHR37419 1 330 1.4E-53 T 22-04-2016 HRM2_RS24205 034272e7c0d61b151665063f1697853a 427 Pfam PF13657 HipA N-terminal domain 8 104 4.8E-22 T 22-04-2016 IPR017508 HipA, N-terminal subdomain 1 HRM2_RS24205 034272e7c0d61b151665063f1697853a 427 Pfam PF07805 HipA-like N-terminal domain 151 231 4.9E-20 T 22-04-2016 IPR012894 HipA, N-terminal subdomain 2 HRM2_RS24205 034272e7c0d61b151665063f1697853a 427 PANTHER PTHR37419:SF3 1 330 1.4E-53 T 22-04-2016 HRM2_RS24205 034272e7c0d61b151665063f1697853a 427 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 7 104 7.0E-25 T 22-04-2016 IPR017508 HipA, N-terminal subdomain 1 HRM2_RS24205 034272e7c0d61b151665063f1697853a 427 Pfam PF07804 HipA-like C-terminal domain 240 382 1.0E-31 T 22-04-2016 IPR012893 HipA-like, C-terminal HRM2_RS01170 574c3b071a436b5e70559e5d7fe9d8cb 588 SUPERFAMILY SSF158472 189 239 3.66E-8 T 22-04-2016 HRM2_RS01170 574c3b071a436b5e70559e5d7fe9d8cb 588 SMART SM00387 477 588 8.1E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS01170 574c3b071a436b5e70559e5d7fe9d8cb 588 SUPERFAMILY SSF55874 420 587 1.83E-46 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS01170 574c3b071a436b5e70559e5d7fe9d8cb 588 Pfam PF00512 His Kinase A (phospho-acceptor) domain 365 430 4.9E-17 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS01170 574c3b071a436b5e70559e5d7fe9d8cb 588 Pfam PF00672 HAMP domain 170 237 1.6E-11 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS01170 574c3b071a436b5e70559e5d7fe9d8cb 588 Pfam PF16736 Single Cache-like 44 149 8.1E-7 T 22-04-2016 IPR031967 PhoR, single Cache-like domain HRM2_RS01170 574c3b071a436b5e70559e5d7fe9d8cb 588 Gene3D G3DSA:1.10.287.130 355 417 1.5E-19 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS01170 574c3b071a436b5e70559e5d7fe9d8cb 588 SMART SM00388 363 431 2.7E-18 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS01170 574c3b071a436b5e70559e5d7fe9d8cb 588 SUPERFAMILY SSF55785 246 355 1.54E-10 T 22-04-2016 IPR000014 PAS domain HRM2_RS01170 574c3b071a436b5e70559e5d7fe9d8cb 588 Pfam PF00989 PAS fold 249 354 8.6E-10 T 22-04-2016 IPR013767 PAS fold GO:0006355 HRM2_RS01170 574c3b071a436b5e70559e5d7fe9d8cb 588 Gene3D G3DSA:3.30.450.20 249 354 2.1E-12 T 22-04-2016 HRM2_RS01170 574c3b071a436b5e70559e5d7fe9d8cb 588 PRINTS PR00344 Bacterial sensor protein C-terminal signature 549 567 1.3E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS01170 574c3b071a436b5e70559e5d7fe9d8cb 588 PRINTS PR00344 Bacterial sensor protein C-terminal signature 532 542 1.3E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS01170 574c3b071a436b5e70559e5d7fe9d8cb 588 PRINTS PR00344 Bacterial sensor protein C-terminal signature 514 528 1.3E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS01170 574c3b071a436b5e70559e5d7fe9d8cb 588 PRINTS PR00344 Bacterial sensor protein C-terminal signature 573 586 1.3E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS01170 574c3b071a436b5e70559e5d7fe9d8cb 588 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 250 362 8.2E-9 T 22-04-2016 IPR000014 PAS domain HRM2_RS01170 574c3b071a436b5e70559e5d7fe9d8cb 588 Gene3D G3DSA:3.30.450.20 35 158 1.4E-14 T 22-04-2016 HRM2_RS01170 574c3b071a436b5e70559e5d7fe9d8cb 588 PANTHER PTHR24423 6 29 5.0E-91 T 22-04-2016 HRM2_RS01170 574c3b071a436b5e70559e5d7fe9d8cb 588 PANTHER PTHR24423 236 588 5.0E-91 T 22-04-2016 HRM2_RS01170 574c3b071a436b5e70559e5d7fe9d8cb 588 SMART SM00091 248 314 0.0039 T 22-04-2016 IPR000014 PAS domain HRM2_RS01170 574c3b071a436b5e70559e5d7fe9d8cb 588 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 482 587 6.8E-24 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS01170 574c3b071a436b5e70559e5d7fe9d8cb 588 SUPERFAMILY SSF47384 349 430 6.28E-19 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS01170 574c3b071a436b5e70559e5d7fe9d8cb 588 SMART SM00304 189 241 1.6E-11 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS01170 574c3b071a436b5e70559e5d7fe9d8cb 588 Gene3D G3DSA:3.30.565.10 418 587 3.8E-47 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS12805 8387e54c3f3992543fe96525e02e478f 435 Gene3D G3DSA:3.40.190.10 72 162 1.9E-13 T 22-04-2016 HRM2_RS12805 8387e54c3f3992543fe96525e02e478f 435 Gene3D G3DSA:3.40.190.10 163 340 5.4E-25 T 22-04-2016 HRM2_RS12805 8387e54c3f3992543fe96525e02e478f 435 SUPERFAMILY SSF53850 73 383 1.74E-44 T 22-04-2016 HRM2_RS12805 8387e54c3f3992543fe96525e02e478f 435 PANTHER PTHR30061 78 340 1.6E-28 T 22-04-2016 HRM2_RS12805 8387e54c3f3992543fe96525e02e478f 435 Pfam PF13416 Bacterial extracellular solute-binding protein 70 341 3.8E-26 T 22-04-2016 HRM2_RS21175 0e764501f321635fb09a82b2f6881854 229 SUPERFAMILY SSF52540 4 219 5.6E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21175 0e764501f321635fb09a82b2f6881854 229 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS21175 0e764501f321635fb09a82b2f6881854 229 Gene3D G3DSA:3.40.50.300 5 223 7.8E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21175 0e764501f321635fb09a82b2f6881854 229 SMART SM00382 31 219 2.4E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS21175 0e764501f321635fb09a82b2f6881854 229 PANTHER PTHR24220:SF430 4 217 2.4E-78 T 22-04-2016 HRM2_RS21175 0e764501f321635fb09a82b2f6881854 229 Pfam PF00005 ABC transporter 23 170 1.5E-29 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS21175 0e764501f321635fb09a82b2f6881854 229 PANTHER PTHR24220 4 217 2.4E-78 T 22-04-2016 HRM2_RS08780 97c1b61e8073fb449645062b3fc28954 171 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 4 151 6.8E-17 T 22-04-2016 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type HRM2_RS08780 97c1b61e8073fb449645062b3fc28954 171 PANTHER PTHR11124 1 151 2.2E-20 T 22-04-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 HRM2_RS08780 97c1b61e8073fb449645062b3fc28954 171 Gene3D G3DSA:3.60.21.10 4 157 1.7E-23 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS08780 97c1b61e8073fb449645062b3fc28954 171 SUPERFAMILY SSF56300 4 155 1.27E-26 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS08780 97c1b61e8073fb449645062b3fc28954 171 PANTHER PTHR11124:SF14 1 151 2.2E-20 T 22-04-2016 HRM2_RS08780 97c1b61e8073fb449645062b3fc28954 171 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 4 155 1.3E-16 T 22-04-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 HRM2_RS15780 03fc849ced47c9f18f68da088d2d8952 216 SUPERFAMILY SSF52499 13 216 5.49E-37 T 22-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 HRM2_RS15780 03fc849ced47c9f18f68da088d2d8952 216 Gene3D G3DSA:3.40.50.850 14 215 4.4E-50 T 22-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 HRM2_RS15780 03fc849ced47c9f18f68da088d2d8952 216 PANTHER PTHR11080:SF2 16 216 8.6E-52 T 22-04-2016 HRM2_RS15780 03fc849ced47c9f18f68da088d2d8952 216 PANTHER PTHR11080 16 216 8.6E-52 T 22-04-2016 HRM2_RS15780 03fc849ced47c9f18f68da088d2d8952 216 Pfam PF00857 Isochorismatase family 13 215 1.3E-27 T 22-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 HRM2_RS05360 a6fb178b3bb95d629ce12e35cac8bb34 428 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 171 305 2.4E-44 T 22-04-2016 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase HRM2_RS05360 a6fb178b3bb95d629ce12e35cac8bb34 428 PIRSF PIRSF000445 2 427 4.1E-154 T 22-04-2016 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 HRM2_RS05360 a6fb178b3bb95d629ce12e35cac8bb34 428 SUPERFAMILY SSF69075 317 420 5.23E-20 T 22-04-2016 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 HRM2_RS05360 a6fb178b3bb95d629ce12e35cac8bb34 428 SUPERFAMILY SSF69742 3 158 4.71E-45 T 22-04-2016 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 HRM2_RS05360 a6fb178b3bb95d629ce12e35cac8bb34 428 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 322 419 3.0E-23 T 22-04-2016 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 HRM2_RS05360 a6fb178b3bb95d629ce12e35cac8bb34 428 PANTHER PTHR13812:SF18 3 420 5.3E-122 T 22-04-2016 HRM2_RS05360 a6fb178b3bb95d629ce12e35cac8bb34 428 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 3 420 30.069 T 22-04-2016 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 HRM2_RS05360 a6fb178b3bb95d629ce12e35cac8bb34 428 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 22-04-2016 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 HRM2_RS05360 a6fb178b3bb95d629ce12e35cac8bb34 428 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 7 156 3.4E-47 T 22-04-2016 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 HRM2_RS05360 a6fb178b3bb95d629ce12e35cac8bb34 428 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 420 8.3E-142 T 22-04-2016 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 HRM2_RS05360 a6fb178b3bb95d629ce12e35cac8bb34 428 Gene3D G3DSA:3.40.50.720 184 359 3.1E-34 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS05360 a6fb178b3bb95d629ce12e35cac8bb34 428 PANTHER PTHR13812 3 420 5.3E-122 T 22-04-2016 HRM2_RS05360 a6fb178b3bb95d629ce12e35cac8bb34 428 SUPERFAMILY SSF51735 162 314 2.27E-32 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS04505 a9ebf845b5e372691adc75d7415ed4cc 724 PANTHER PTHR21432 432 660 3.2E-112 T 22-04-2016 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 HRM2_RS04505 a9ebf845b5e372691adc75d7415ed4cc 724 Gene3D G3DSA:3.40.810.20 485 615 3.1E-12 T 22-04-2016 HRM2_RS04505 a9ebf845b5e372691adc75d7415ed4cc 724 PANTHER PTHR21432:SF18 432 660 3.2E-112 T 22-04-2016 HRM2_RS04505 a9ebf845b5e372691adc75d7415ed4cc 724 PANTHER PTHR21432 24 69 3.2E-112 T 22-04-2016 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 HRM2_RS04505 a9ebf845b5e372691adc75d7415ed4cc 724 PANTHER PTHR21432 98 282 3.2E-112 T 22-04-2016 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 HRM2_RS04505 a9ebf845b5e372691adc75d7415ed4cc 724 Gene3D G3DSA:3.30.750.70 431 455 3.0E-31 T 22-04-2016 HRM2_RS04505 a9ebf845b5e372691adc75d7415ed4cc 724 Gene3D G3DSA:3.30.750.70 311 341 3.0E-31 T 22-04-2016 HRM2_RS04505 a9ebf845b5e372691adc75d7415ed4cc 724 Gene3D G3DSA:3.30.750.70 231 276 3.0E-31 T 22-04-2016 HRM2_RS04505 a9ebf845b5e372691adc75d7415ed4cc 724 PANTHER PTHR21432 316 342 3.2E-112 T 22-04-2016 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 HRM2_RS04505 a9ebf845b5e372691adc75d7415ed4cc 724 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 440 603 1.1E-44 T 22-04-2016 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain HRM2_RS04505 a9ebf845b5e372691adc75d7415ed4cc 724 PANTHER PTHR21432:SF18 98 282 3.2E-112 T 22-04-2016 HRM2_RS04505 a9ebf845b5e372691adc75d7415ed4cc 724 PANTHER PTHR21432:SF18 24 69 3.2E-112 T 22-04-2016 HRM2_RS04505 a9ebf845b5e372691adc75d7415ed4cc 724 SUPERFAMILY SSF100950 306 334 2.09E-44 T 22-04-2016 HRM2_RS04505 a9ebf845b5e372691adc75d7415ed4cc 724 SUPERFAMILY SSF100950 427 629 2.09E-44 T 22-04-2016 HRM2_RS04505 a9ebf845b5e372691adc75d7415ed4cc 724 SUPERFAMILY SSF100950 232 273 2.09E-44 T 22-04-2016 HRM2_RS04505 a9ebf845b5e372691adc75d7415ed4cc 724 PANTHER PTHR21432:SF18 316 342 3.2E-112 T 22-04-2016 HRM2_RS13570 5b39ba105d691d81edd78e79d82e90cd 170 PANTHER PTHR35011:SF4 4 161 4.2E-16 T 22-04-2016 HRM2_RS13570 5b39ba105d691d81edd78e79d82e90cd 170 PANTHER PTHR35011 4 161 4.2E-16 T 22-04-2016 HRM2_RS13570 5b39ba105d691d81edd78e79d82e90cd 170 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 29 161 1.8E-25 T 22-04-2016 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component HRM2_RS16125 58cbffc49e0fca6f0e6d0c08394508d9 128 PANTHER PTHR11527 24 126 4.1E-24 T 22-04-2016 IPR031107 Small heat shock protein HSP20 HRM2_RS16125 58cbffc49e0fca6f0e6d0c08394508d9 128 PANTHER PTHR11527:SF118 24 126 4.1E-24 T 22-04-2016 HRM2_RS16125 58cbffc49e0fca6f0e6d0c08394508d9 128 SUPERFAMILY SSF49764 23 126 1.17E-30 T 22-04-2016 IPR008978 HSP20-like chaperone HRM2_RS16125 58cbffc49e0fca6f0e6d0c08394508d9 128 Pfam PF00011 Hsp20/alpha crystallin family 29 126 3.4E-20 T 22-04-2016 IPR002068 Alpha crystallin/Hsp20 domain HRM2_RS16125 58cbffc49e0fca6f0e6d0c08394508d9 128 Gene3D G3DSA:2.60.40.790 21 126 1.0E-28 T 22-04-2016 IPR008978 HSP20-like chaperone HRM2_RS13555 bc79b14cb9955c01bddfccd2f26f2cc4 379 PANTHER PTHR11014 2 379 2.6E-98 T 22-04-2016 HRM2_RS13555 bc79b14cb9955c01bddfccd2f26f2cc4 379 SUPERFAMILY SSF53187 292 372 2.88E-55 T 22-04-2016 HRM2_RS13555 bc79b14cb9955c01bddfccd2f26f2cc4 379 SUPERFAMILY SSF53187 6 176 2.88E-55 T 22-04-2016 HRM2_RS13555 bc79b14cb9955c01bddfccd2f26f2cc4 379 Gene3D G3DSA:3.30.70.360 178 275 6.1E-25 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain HRM2_RS13555 bc79b14cb9955c01bddfccd2f26f2cc4 379 SUPERFAMILY SSF55031 178 276 1.03E-20 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain HRM2_RS13555 bc79b14cb9955c01bddfccd2f26f2cc4 379 TIGRFAM TIGR01883 PepT-like: peptidase T-like protein 6 371 7.1E-93 T 22-04-2016 IPR010162 Peptidase M20B, peptidase T HRM2_RS13555 bc79b14cb9955c01bddfccd2f26f2cc4 379 Pfam PF01546 Peptidase family M20/M25/M40 72 371 3.3E-21 T 22-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 HRM2_RS13555 bc79b14cb9955c01bddfccd2f26f2cc4 379 Gene3D G3DSA:3.40.630.10 292 372 2.7E-60 T 22-04-2016 HRM2_RS13555 bc79b14cb9955c01bddfccd2f26f2cc4 379 Gene3D G3DSA:3.40.630.10 1 176 2.7E-60 T 22-04-2016 HRM2_RS13555 bc79b14cb9955c01bddfccd2f26f2cc4 379 Pfam PF07687 Peptidase dimerisation domain 179 271 1.5E-16 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain HRM2_RS13555 bc79b14cb9955c01bddfccd2f26f2cc4 379 PANTHER PTHR11014:SF61 2 379 2.6E-98 T 22-04-2016 HRM2_RS13555 bc79b14cb9955c01bddfccd2f26f2cc4 379 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 71 80 - T 22-04-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 HRM2_RS01260 10c25bf696c218251d671bc583fe0640 266 PIRSF PIRSF003092 1 264 1.9E-78 T 22-04-2016 IPR025501 ATP binding protein MinD HRM2_RS01260 10c25bf696c218251d671bc583fe0640 266 SUPERFAMILY SSF52540 3 258 1.0E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01260 10c25bf696c218251d671bc583fe0640 266 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 4 259 1.2E-105 T 22-04-2016 IPR010223 ATP binding protein MinD, bacterial-type GO:0000918|GO:0016887 HRM2_RS01260 10c25bf696c218251d671bc583fe0640 266 Gene3D G3DSA:3.40.50.300 3 237 1.2E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01260 10c25bf696c218251d671bc583fe0640 266 PANTHER PTHR13696:SF1 2 249 1.7E-83 T 22-04-2016 HRM2_RS01260 10c25bf696c218251d671bc583fe0640 266 PANTHER PTHR13696 2 249 1.7E-83 T 22-04-2016 HRM2_RS01260 10c25bf696c218251d671bc583fe0640 266 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 208 5.5E-29 T 22-04-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain HRM2_RS09380 c29518c9212d9d77bc7a39d2dc20b8e8 291 Gene3D G3DSA:3.40.50.300 17 168 2.3E-28 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09380 c29518c9212d9d77bc7a39d2dc20b8e8 291 Pfam PF01926 50S ribosome-binding GTPase 114 175 2.2E-14 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS09380 c29518c9212d9d77bc7a39d2dc20b8e8 291 PANTHER PTHR11089 1 271 3.9E-57 T 22-04-2016 HRM2_RS09380 c29518c9212d9d77bc7a39d2dc20b8e8 291 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 115 135 5.0E-5 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS09380 c29518c9212d9d77bc7a39d2dc20b8e8 291 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 176 5.0E-5 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS09380 c29518c9212d9d77bc7a39d2dc20b8e8 291 SUPERFAMILY SSF52540 9 175 2.41E-33 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09380 c29518c9212d9d77bc7a39d2dc20b8e8 291 PIRSF PIRSF006230 1 276 3.5E-89 T 22-04-2016 IPR016478 GTPase, MTG1 HRM2_RS09380 c29518c9212d9d77bc7a39d2dc20b8e8 291 PANTHER PTHR11089:SF4 1 271 3.9E-57 T 22-04-2016 HRM2_RS09380 c29518c9212d9d77bc7a39d2dc20b8e8 291 Gene3D G3DSA:1.10.1580.10 173 265 1.6E-25 T 22-04-2016 IPR023179 GTP-binding protein, orthogonal bundle domain HRM2_RS09380 c29518c9212d9d77bc7a39d2dc20b8e8 291 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 3 271 2.8E-87 T 22-04-2016 IPR019991 GTP-binding protein, ribosome biogenesis HRM2_RS01745 b70f1553cfee036b3a263ddbceb77833 252 PIRSF PIRSF018982 2 252 1.7E-89 T 22-04-2016 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7|UniPathway: UPA00560 HRM2_RS01745 b70f1553cfee036b3a263ddbceb77833 252 PANTHER PTHR39330 13 250 2.9E-82 T 22-04-2016 HRM2_RS01745 b70f1553cfee036b3a263ddbceb77833 252 Pfam PF05985 Ethanolamine ammonia-lyase light chain (EutC) 10 246 2.2E-89 T 22-04-2016 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7|UniPathway: UPA00560 HRM2_RS13785 d3ce429fd0f0caffaca136bc0c8ec876 170 Gene3D G3DSA:2.60.450.10 21 157 4.8E-25 T 22-04-2016 HRM2_RS13785 d3ce429fd0f0caffaca136bc0c8ec876 170 PANTHER PTHR36504 1 170 4.5E-12 T 22-04-2016 HRM2_RS13785 d3ce429fd0f0caffaca136bc0c8ec876 170 Pfam PF03968 OstA-like protein 26 141 4.4E-12 T 22-04-2016 IPR005653 Organic solvent tolerance-like, N-terminal HRM2_RS13420 5b4f9a68eacd1441d1da2e3d7e20940e 565 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 237 385 2.3E-14 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS13420 5b4f9a68eacd1441d1da2e3d7e20940e 565 SUPERFAMILY SSF56645 14 201 1.07E-20 T 22-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 HRM2_RS13420 5b4f9a68eacd1441d1da2e3d7e20940e 565 PANTHER PTHR10909 2 405 6.4E-234 T 22-04-2016 HRM2_RS13420 5b4f9a68eacd1441d1da2e3d7e20940e 565 SUPERFAMILY SSF47203 235 390 2.26E-24 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS13420 5b4f9a68eacd1441d1da2e3d7e20940e 565 Gene3D G3DSA:2.40.110.10 131 187 9.8E-9 T 22-04-2016 HRM2_RS13420 5b4f9a68eacd1441d1da2e3d7e20940e 565 PANTHER PTHR10909:SF207 2 405 6.4E-234 T 22-04-2016 HRM2_RS13420 5b4f9a68eacd1441d1da2e3d7e20940e 565 Gene3D G3DSA:1.20.140.10 221 387 1.8E-16 T 22-04-2016 HRM2_RS00045 af0156be099ad42f162f34af51887994 342 SUPERFAMILY SSF102114 102 292 2.75E-9 T 22-04-2016 HRM2_RS00045 af0156be099ad42f162f34af51887994 342 Pfam PF04055 Radical SAM superfamily 105 271 3.4E-13 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS00045 af0156be099ad42f162f34af51887994 342 PANTHER PTHR30544:SF5 2 342 1.8E-104 T 22-04-2016 HRM2_RS00045 af0156be099ad42f162f34af51887994 342 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 2 339 1.1E-87 T 22-04-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HRM2_RS00045 af0156be099ad42f162f34af51887994 342 Gene3D G3DSA:3.20.20.70 101 315 2.4E-10 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS00045 af0156be099ad42f162f34af51887994 342 PIRSF PIRSF006004 1 342 6.6E-95 T 22-04-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HRM2_RS00045 af0156be099ad42f162f34af51887994 342 PANTHER PTHR30544 2 342 1.8E-104 T 22-04-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HRM2_RS07515 fc008cbfdfc1bf58664493a91958b76e 310 PANTHER PTHR10422 18 142 1.5E-17 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 HRM2_RS07515 fc008cbfdfc1bf58664493a91958b76e 310 Gene3D G3DSA:1.10.760.10 18 151 8.4E-15 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 HRM2_RS07515 fc008cbfdfc1bf58664493a91958b76e 310 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 207 288 1.1E-10 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 HRM2_RS07515 fc008cbfdfc1bf58664493a91958b76e 310 PANTHER PTHR10422:SF23 18 142 1.5E-17 T 22-04-2016 HRM2_RS07515 fc008cbfdfc1bf58664493a91958b76e 310 SUPERFAMILY SSF46626 187 290 7.16E-18 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 HRM2_RS07515 fc008cbfdfc1bf58664493a91958b76e 310 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 12 160 1.7E-32 T 22-04-2016 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO HRM2_RS07515 fc008cbfdfc1bf58664493a91958b76e 310 Gene3D G3DSA:1.10.760.10 196 290 4.8E-16 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 HRM2_RS07515 fc008cbfdfc1bf58664493a91958b76e 310 SUPERFAMILY SSF46626 14 143 4.51E-15 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 HRM2_RS05010 0d671199ad6aa0728136ec873dabb838 437 SMART SM00220 174 422 2.3E-42 T 22-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 HRM2_RS05010 0d671199ad6aa0728136ec873dabb838 437 Gene3D G3DSA:1.10.510.10 285 418 3.0E-33 T 22-04-2016 HRM2_RS05010 0d671199ad6aa0728136ec873dabb838 437 Gene3D G3DSA:3.30.200.20 173 284 5.4E-23 T 22-04-2016 HRM2_RS05010 0d671199ad6aa0728136ec873dabb838 437 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 287 299 - T 22-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 HRM2_RS05010 0d671199ad6aa0728136ec873dabb838 437 SUPERFAMILY SSF52172 48 135 2.36E-6 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS05010 0d671199ad6aa0728136ec873dabb838 437 Pfam PF00069 Protein kinase domain 197 416 1.2E-40 T 22-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 HRM2_RS05010 0d671199ad6aa0728136ec873dabb838 437 SUPERFAMILY SSF56112 172 418 2.97E-56 T 22-04-2016 IPR011009 Protein kinase-like domain HRM2_RS05010 0d671199ad6aa0728136ec873dabb838 437 PANTHER PTHR24362 170 411 1.4E-53 T 22-04-2016 HRM2_RS19905 5139bca2109d89cc03a8243e4fa322a7 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 51 9.6E-13 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS19905 5139bca2109d89cc03a8243e4fa322a7 194 Gene3D G3DSA:1.10.357.10 50 190 4.5E-16 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HRM2_RS19905 5139bca2109d89cc03a8243e4fa322a7 194 PANTHER PTHR30055 4 165 1.4E-21 T 22-04-2016 HRM2_RS19905 5139bca2109d89cc03a8243e4fa322a7 194 SUPERFAMILY SSF46689 3 72 6.98E-16 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS19905 5139bca2109d89cc03a8243e4fa322a7 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 1.2E-9 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS19905 5139bca2109d89cc03a8243e4fa322a7 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 1.2E-9 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS19905 5139bca2109d89cc03a8243e4fa322a7 194 ProSitePatterns PS01081 TetR-type HTH domain signature. 19 49 - T 22-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site HRM2_RS19905 5139bca2109d89cc03a8243e4fa322a7 194 Gene3D G3DSA:1.10.10.60 3 49 1.6E-16 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS19905 5139bca2109d89cc03a8243e4fa322a7 194 SUPERFAMILY SSF48498 78 169 1.82E-7 T 22-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal HRM2_RS05340 a0a2b00234ac4d4be1b7919a0681018e 798 SUPERFAMILY SSF53955 65 275 2.25E-74 T 22-04-2016 IPR023346 Lysozyme-like domain HRM2_RS05340 a0a2b00234ac4d4be1b7919a0681018e 798 Gene3D G3DSA:3.40.710.10 255 337 1.4E-135 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HRM2_RS05340 a0a2b00234ac4d4be1b7919a0681018e 798 Gene3D G3DSA:3.40.710.10 452 780 1.4E-135 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HRM2_RS05340 a0a2b00234ac4d4be1b7919a0681018e 798 Pfam PF00905 Penicillin binding protein transpeptidase domain 462 702 8.1E-37 T 22-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 HRM2_RS05340 a0a2b00234ac4d4be1b7919a0681018e 798 Pfam PF00912 Transglycosylase 78 253 4.0E-65 T 22-04-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 HRM2_RS05340 a0a2b00234ac4d4be1b7919a0681018e 798 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 88 733 1.3E-195 T 22-04-2016 HRM2_RS05340 a0a2b00234ac4d4be1b7919a0681018e 798 PANTHER PTHR32282:SF5 451 791 2.2E-255 T 22-04-2016 HRM2_RS05340 a0a2b00234ac4d4be1b7919a0681018e 798 PANTHER PTHR32282:SF5 5 334 2.2E-255 T 22-04-2016 HRM2_RS05340 a0a2b00234ac4d4be1b7919a0681018e 798 SMART SM00316 369 450 3.7E-9 T 22-04-2016 IPR022967 RNA-binding domain, S1 HRM2_RS05340 a0a2b00234ac4d4be1b7919a0681018e 798 SUPERFAMILY SSF56601 285 337 2.82E-133 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HRM2_RS05340 a0a2b00234ac4d4be1b7919a0681018e 798 SUPERFAMILY SSF56601 452 784 2.82E-133 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HRM2_RS05340 a0a2b00234ac4d4be1b7919a0681018e 798 SUPERFAMILY SSF56601 234 256 2.82E-133 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HRM2_RS05340 a0a2b00234ac4d4be1b7919a0681018e 798 Pfam PF17092 Penicillin-binding protein OB-like domain 340 455 4.8E-15 T 22-04-2016 IPR031376 Penicillin-binding protein, OB-like domain KEGG: 00230+2.4.2.-|KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00514+2.4.2.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.-|UniPathway: UPA00219 HRM2_RS05340 a0a2b00234ac4d4be1b7919a0681018e 798 Gene3D G3DSA:2.40.50.140 366 451 3.5E-9 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS05340 a0a2b00234ac4d4be1b7919a0681018e 798 SUPERFAMILY SSF50249 369 438 4.63E-9 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS05340 a0a2b00234ac4d4be1b7919a0681018e 798 PANTHER PTHR32282 451 791 2.2E-255 T 22-04-2016 HRM2_RS05340 a0a2b00234ac4d4be1b7919a0681018e 798 PANTHER PTHR32282 5 334 2.2E-255 T 22-04-2016 HRM2_RS05340 a0a2b00234ac4d4be1b7919a0681018e 798 Gene3D G3DSA:1.10.3810.10 79 254 3.2E-73 T 22-04-2016 HRM2_RS09475 aea45ca055a9a67f95134b4099afcf37 154 SUPERFAMILY SSF74982 3 132 6.15E-52 T 22-04-2016 IPR023620 Small protein B HRM2_RS09475 aea45ca055a9a67f95134b4099afcf37 154 Hamap MF_00023 SsrA-binding protein [smpB]. 1 154 70.281 T 22-04-2016 IPR000037 SsrA-binding protein GO:0003723 HRM2_RS09475 aea45ca055a9a67f95134b4099afcf37 154 PANTHER PTHR30308 6 154 4.7E-76 T 22-04-2016 HRM2_RS09475 aea45ca055a9a67f95134b4099afcf37 154 PANTHER PTHR30308:SF2 6 154 4.7E-76 T 22-04-2016 HRM2_RS09475 aea45ca055a9a67f95134b4099afcf37 154 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 9 132 8.0E-42 T 22-04-2016 IPR000037 SsrA-binding protein GO:0003723 HRM2_RS09475 aea45ca055a9a67f95134b4099afcf37 154 ProSitePatterns PS01317 SsrA-binding protein. 27 39 - T 22-04-2016 IPR020081 SsrA-binding protein, conserved site HRM2_RS09475 aea45ca055a9a67f95134b4099afcf37 154 Pfam PF01668 SmpB protein 8 70 4.8E-30 T 22-04-2016 IPR000037 SsrA-binding protein GO:0003723 HRM2_RS09475 aea45ca055a9a67f95134b4099afcf37 154 Gene3D G3DSA:2.40.280.10 7 127 2.1E-51 T 22-04-2016 IPR023620 Small protein B HRM2_RS09475 aea45ca055a9a67f95134b4099afcf37 154 TIGRFAM TIGR00086 smpB: SsrA-binding protein 8 148 3.1E-58 T 22-04-2016 IPR000037 SsrA-binding protein GO:0003723 HRM2_RS02875 854929690999866edce44807a52ed5ac 146 Pfam PF12724 Flavodoxin domain 5 81 4.5E-9 T 22-04-2016 IPR026816 Flavodoxin domain HRM2_RS02875 854929690999866edce44807a52ed5ac 146 SUPERFAMILY SSF52218 1 146 7.47E-28 T 22-04-2016 IPR029039 Flavoprotein-like domain HRM2_RS02875 854929690999866edce44807a52ed5ac 146 Gene3D G3DSA:3.40.50.360 3 146 9.8E-30 T 22-04-2016 IPR029039 Flavoprotein-like domain HRM2_RS18945 38c99420a9156ecfdb97f901d975e140 188 PANTHER PTHR10204 1 128 7.6E-38 T 22-04-2016 HRM2_RS18945 38c99420a9156ecfdb97f901d975e140 188 Pfam PF03358 NADPH-dependent FMN reductase 1 113 1.0E-22 T 22-04-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 HRM2_RS18945 38c99420a9156ecfdb97f901d975e140 188 Gene3D G3DSA:3.40.50.360 1 187 6.6E-42 T 22-04-2016 IPR029039 Flavoprotein-like domain HRM2_RS18945 38c99420a9156ecfdb97f901d975e140 188 PANTHER PTHR10204:SF5 1 128 7.6E-38 T 22-04-2016 HRM2_RS18945 38c99420a9156ecfdb97f901d975e140 188 SUPERFAMILY SSF52218 1 187 1.24E-35 T 22-04-2016 IPR029039 Flavoprotein-like domain HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 Pfam PF00515 Tetratricopeptide repeat 501 531 1.3E-6 T 22-04-2016 IPR001440 Tetratricopeptide repeat 1 GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 Gene3D G3DSA:1.25.40.10 30 226 5.9E-34 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 Gene3D G3DSA:1.25.40.10 415 557 1.5E-26 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 Gene3D G3DSA:1.25.40.10 237 391 6.1E-23 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 Gene3D G3DSA:1.25.40.10 573 781 3.3E-35 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 SMART SM00028 68 101 37.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 SMART SM00028 170 204 37.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 SMART SM00028 274 307 0.028 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 SMART SM00028 102 135 35.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 SMART SM00028 136 169 0.015 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 SMART SM00028 431 464 110.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 SMART SM00028 742 775 6.6E-4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 SMART SM00028 239 272 86.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 SMART SM00028 465 498 13.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 SMART SM00028 639 672 1.4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 SMART SM00028 571 604 23.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 SMART SM00028 34 67 19.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 SMART SM00028 308 340 72.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 SMART SM00028 708 741 0.42 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 SMART SM00028 605 638 140.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 SMART SM00028 341 374 120.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 SMART SM00028 499 532 1.1E-5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 Pfam PF13174 Tetratricopeptide repeat 103 134 0.0056 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 Pfam PF13181 Tetratricopeptide repeat 640 670 1.4E-5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 Pfam PF13181 Tetratricopeptide repeat 573 599 0.022 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 Pfam PF13181 Tetratricopeptide repeat 137 168 0.009 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 Pfam PF13181 Tetratricopeptide repeat 170 202 9.4E-4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 PANTHER PTHR23083 270 395 1.5E-76 T 22-04-2016 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 PANTHER PTHR23083 35 204 1.5E-76 T 22-04-2016 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 PANTHER PTHR23083 416 531 1.5E-76 T 22-04-2016 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 PANTHER PTHR23083 638 785 1.5E-76 T 22-04-2016 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 Pfam PF07719 Tetratricopeptide repeat 743 774 1.7E-7 T 22-04-2016 IPR013105 Tetratricopeptide repeat 2 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 Pfam PF12895 Anaphase-promoting complex, cyclosome, subunit 3 287 366 2.8E-7 T 22-04-2016 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 SUPERFAMILY SSF48452 352 428 2.09E-37 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 SUPERFAMILY SSF48452 463 783 2.09E-37 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 SUPERFAMILY SSF48452 32 207 1.33E-33 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS09710 edde21cf846bf747af383ff7943dfa33 787 SUPERFAMILY SSF48452 242 343 1.33E-33 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS23355 d3c0a4e1b19c6df0796aa25d4670daf2 623 Gene3D G3DSA:3.30.450.90 205 328 7.4E-41 T 22-04-2016 HRM2_RS23355 d3c0a4e1b19c6df0796aa25d4670daf2 623 SUPERFAMILY SSF52540 215 604 6.65E-82 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23355 d3c0a4e1b19c6df0796aa25d4670daf2 623 PANTHER PTHR30258:SF2 60 617 1.9E-159 T 22-04-2016 HRM2_RS23355 d3c0a4e1b19c6df0796aa25d4670daf2 623 SUPERFAMILY SSF160246 69 206 1.12E-31 T 22-04-2016 HRM2_RS23355 d3c0a4e1b19c6df0796aa25d4670daf2 623 Pfam PF00437 Type II/IV secretion system protein 230 496 2.2E-63 T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 HRM2_RS23355 d3c0a4e1b19c6df0796aa25d4670daf2 623 Gene3D G3DSA:3.40.50.300 333 605 9.4E-78 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23355 d3c0a4e1b19c6df0796aa25d4670daf2 623 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 424 438 - T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 HRM2_RS23355 d3c0a4e1b19c6df0796aa25d4670daf2 623 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 108 208 2.6E-20 T 22-04-2016 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 HRM2_RS23355 d3c0a4e1b19c6df0796aa25d4670daf2 623 PANTHER PTHR30258 60 617 1.9E-159 T 22-04-2016 HRM2_RS00300 9b37e2077841cb5bd62fb4bc8cfed7fc 228 PANTHER PTHR30598 1 219 5.0E-68 T 22-04-2016 HRM2_RS00300 9b37e2077841cb5bd62fb4bc8cfed7fc 228 PANTHER PTHR30598:SF3 1 219 5.0E-68 T 22-04-2016 HRM2_RS00300 9b37e2077841cb5bd62fb4bc8cfed7fc 228 Pfam PF02665 Nitrate reductase gamma subunit 7 219 4.3E-71 T 22-04-2016 IPR023234 NarG-like domain HRM2_RS00300 9b37e2077841cb5bd62fb4bc8cfed7fc 228 SUPERFAMILY SSF103501 1 219 4.32E-50 T 22-04-2016 IPR023234 NarG-like domain HRM2_RS00300 9b37e2077841cb5bd62fb4bc8cfed7fc 228 Gene3D G3DSA:1.20.950.20 3 212 3.8E-58 T 22-04-2016 HRM2_RS00300 9b37e2077841cb5bd62fb4bc8cfed7fc 228 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 5 219 2.8E-52 T 22-04-2016 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 KEGG: 00910+1.7.99.4 HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 Gene3D G3DSA:3.40.50.2300 586 714 1.0E-35 T 22-04-2016 HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 SMART SM00086 273 315 0.0052 T 22-04-2016 IPR001610 PAC motif HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 Gene3D G3DSA:3.40.50.2300 10 167 1.1E-29 T 22-04-2016 HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 SMART SM00387 444 567 2.3E-27 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 Gene3D G3DSA:3.30.565.10 389 568 4.7E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 PANTHER PTHR24423 96 139 1.1E-137 T 22-04-2016 HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 PANTHER PTHR24423 273 709 1.1E-137 T 22-04-2016 HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 269 321 8.0E-8 T 22-04-2016 IPR000014 PAS domain HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 Gene3D G3DSA:3.30.450.20 193 329 3.0E-15 T 22-04-2016 HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 SUPERFAMILY SSF52172 11 176 1.99E-13 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 PRINTS PR00344 Bacterial sensor protein C-terminal signature 551 564 4.2E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 PRINTS PR00344 Bacterial sensor protein C-terminal signature 527 545 4.2E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 PRINTS PR00344 Bacterial sensor protein C-terminal signature 496 510 4.2E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 PRINTS PR00344 Bacterial sensor protein C-terminal signature 514 524 4.2E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 Pfam PF08448 PAS fold 197 316 2.2E-9 T 22-04-2016 IPR013656 PAS fold-4 HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 Gene3D G3DSA:1.10.287.130 334 388 1.7E-5 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 PANTHER PTHR24423:SF458 96 139 1.1E-137 T 22-04-2016 HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 PANTHER PTHR24423:SF458 273 709 1.1E-137 T 22-04-2016 HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 Pfam PF00072 Response regulator receiver domain 588 699 4.2E-26 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 Pfam PF00072 Response regulator receiver domain 53 153 4.9E-7 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 SMART SM00388 337 403 8.1E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 Pfam PF00512 His Kinase A (phospho-acceptor) domain 337 400 8.2E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 SMART SM00448 10 155 0.051 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 SMART SM00448 586 699 9.3E-32 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 SUPERFAMILY SSF47384 331 399 3.53E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 SUPERFAMILY SSF55785 199 315 2.09E-10 T 22-04-2016 IPR000014 PAS domain HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 445 564 5.8E-18 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 SUPERFAMILY SSF55874 393 568 1.44E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25060 1125385060ccd2b97de56944bc787d02 716 SUPERFAMILY SSF52172 586 707 1.71E-34 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS08820 ae03690564acda80025c2d6fcf808377 497 PANTHER PTHR11236:SF9 1 490 1.7E-204 T 22-04-2016 HRM2_RS08820 ae03690564acda80025c2d6fcf808377 497 PRINTS PR00095 Anthranilate synthase component I signature 421 435 5.9E-25 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 HRM2_RS08820 ae03690564acda80025c2d6fcf808377 497 PRINTS PR00095 Anthranilate synthase component I signature 436 450 5.9E-25 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 HRM2_RS08820 ae03690564acda80025c2d6fcf808377 497 PRINTS PR00095 Anthranilate synthase component I signature 327 340 5.9E-25 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 HRM2_RS08820 ae03690564acda80025c2d6fcf808377 497 PRINTS PR00095 Anthranilate synthase component I signature 341 354 5.9E-25 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 HRM2_RS08820 ae03690564acda80025c2d6fcf808377 497 Gene3D G3DSA:3.60.120.10 18 489 3.0E-161 T 22-04-2016 IPR005801 ADC synthase GO:0009058 HRM2_RS08820 ae03690564acda80025c2d6fcf808377 497 SUPERFAMILY SSF56322 20 488 5.76E-150 T 22-04-2016 IPR005801 ADC synthase GO:0009058 HRM2_RS08820 ae03690564acda80025c2d6fcf808377 497 Pfam PF04715 Anthranilate synthase component I, N terminal region 31 171 5.2E-28 T 22-04-2016 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 HRM2_RS08820 ae03690564acda80025c2d6fcf808377 497 PANTHER PTHR11236 1 490 1.7E-204 T 22-04-2016 HRM2_RS08820 ae03690564acda80025c2d6fcf808377 497 Pfam PF00425 chorismate binding enzyme 227 479 2.9E-95 T 22-04-2016 IPR015890 Chorismate-utilising enzyme, C-terminal HRM2_RS11575 6b0cb34618d5f48b0d56afbbcd4af80b 556 Gene3D G3DSA:3.90.800.10 101 209 2.8E-47 T 22-04-2016 HRM2_RS11575 6b0cb34618d5f48b0d56afbbcd4af80b 556 Gene3D G3DSA:2.40.240.10 462 550 1.5E-30 T 22-04-2016 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: REACT_71 HRM2_RS11575 6b0cb34618d5f48b0d56afbbcd4af80b 556 PANTHER PTHR11451 267 556 1.7E-225 T 22-04-2016 HRM2_RS11575 6b0cb34618d5f48b0d56afbbcd4af80b 556 PANTHER PTHR11451 6 247 1.7E-225 T 22-04-2016 HRM2_RS11575 6b0cb34618d5f48b0d56afbbcd4af80b 556 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 34 45 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS11575 6b0cb34618d5f48b0d56afbbcd4af80b 556 Gene3D G3DSA:1.10.1160.10 262 339 3.2E-35 T 22-04-2016 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: REACT_71 HRM2_RS11575 6b0cb34618d5f48b0d56afbbcd4af80b 556 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 340 531 6.4E-60 T 22-04-2016 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: REACT_71 HRM2_RS11575 6b0cb34618d5f48b0d56afbbcd4af80b 556 Gene3D G3DSA:3.40.50.620 212 261 7.0E-43 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS11575 6b0cb34618d5f48b0d56afbbcd4af80b 556 Gene3D G3DSA:3.40.50.620 28 96 7.0E-43 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS11575 6b0cb34618d5f48b0d56afbbcd4af80b 556 Gene3D G3DSA:2.40.240.10 348 461 8.4E-50 T 22-04-2016 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: REACT_71 HRM2_RS11575 6b0cb34618d5f48b0d56afbbcd4af80b 556 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 28 554 1.4E-235 T 22-04-2016 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18 HRM2_RS11575 6b0cb34618d5f48b0d56afbbcd4af80b 556 SUPERFAMILY SSF50715 340 551 2.2E-74 T 22-04-2016 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: REACT_71 HRM2_RS11575 6b0cb34618d5f48b0d56afbbcd4af80b 556 PRINTS PR00987 Glutamyl-tRNA synthetase signature 45 56 2.0E-9 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 HRM2_RS11575 6b0cb34618d5f48b0d56afbbcd4af80b 556 PRINTS PR00987 Glutamyl-tRNA synthetase signature 31 43 2.0E-9 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 HRM2_RS11575 6b0cb34618d5f48b0d56afbbcd4af80b 556 PRINTS PR00987 Glutamyl-tRNA synthetase signature 60 73 2.0E-9 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 HRM2_RS11575 6b0cb34618d5f48b0d56afbbcd4af80b 556 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 220 2.0E-9 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 HRM2_RS11575 6b0cb34618d5f48b0d56afbbcd4af80b 556 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 28 337 2.3E-112 T 22-04-2016 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 Reactome: REACT_71 HRM2_RS11575 6b0cb34618d5f48b0d56afbbcd4af80b 556 SUPERFAMILY SSF52374 24 337 7.7E-103 T 22-04-2016 HRM2_RS11575 6b0cb34618d5f48b0d56afbbcd4af80b 556 PANTHER PTHR11451:SF29 267 556 1.7E-225 T 22-04-2016 HRM2_RS11575 6b0cb34618d5f48b0d56afbbcd4af80b 556 PANTHER PTHR11451:SF29 6 247 1.7E-225 T 22-04-2016 HRM2_RS11575 6b0cb34618d5f48b0d56afbbcd4af80b 556 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 552 52.197 T 22-04-2016 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 HRM2_RS20505 6089d614a3226dc4e0055c6fe1605fbd 165 PANTHER PTHR24567 11 163 5.5E-16 T 22-04-2016 HRM2_RS20505 6089d614a3226dc4e0055c6fe1605fbd 165 PANTHER PTHR24567:SF30 11 163 5.5E-16 T 22-04-2016 HRM2_RS20505 6089d614a3226dc4e0055c6fe1605fbd 165 Gene3D G3DSA:2.60.120.10 17 149 4.4E-27 T 22-04-2016 IPR014710 RmlC-like jelly roll fold HRM2_RS20505 6089d614a3226dc4e0055c6fe1605fbd 165 SUPERFAMILY SSF51206 16 146 1.96E-29 T 22-04-2016 IPR018490 Cyclic nucleotide-binding-like HRM2_RS20505 6089d614a3226dc4e0055c6fe1605fbd 165 Pfam PF00027 Cyclic nucleotide-binding domain 49 135 2.4E-18 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain HRM2_RS20505 6089d614a3226dc4e0055c6fe1605fbd 165 SMART SM00100 31 151 4.5E-12 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain HRM2_RS15420 4ccb8f8f1fa1971316fa22dc3b8d026b 143 PANTHER PTHR11078 1 131 6.7E-43 T 22-04-2016 IPR011605 NusB antitermination factor GO:0006353 HRM2_RS15420 4ccb8f8f1fa1971316fa22dc3b8d026b 143 Gene3D G3DSA:1.10.940.10 1 131 3.5E-43 T 22-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 HRM2_RS15420 4ccb8f8f1fa1971316fa22dc3b8d026b 143 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 2 136 21.951 T 22-04-2016 IPR011605 NusB antitermination factor GO:0006353 HRM2_RS15420 4ccb8f8f1fa1971316fa22dc3b8d026b 143 SUPERFAMILY SSF48013 4 131 5.49E-38 T 22-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 HRM2_RS15420 4ccb8f8f1fa1971316fa22dc3b8d026b 143 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 4 131 1.3E-41 T 22-04-2016 IPR011605 NusB antitermination factor GO:0006353 HRM2_RS15420 4ccb8f8f1fa1971316fa22dc3b8d026b 143 Pfam PF01029 NusB family 5 131 1.9E-34 T 22-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 HRM2_RS05165 9b3f6eb712053797b1e0b6d05e9ad478 471 SUPERFAMILY SSF52540 143 385 4.26E-72 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05165 9b3f6eb712053797b1e0b6d05e9ad478 471 SMART SM00382 163 306 6.5E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS05165 9b3f6eb712053797b1e0b6d05e9ad478 471 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 229 244 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS05165 9b3f6eb712053797b1e0b6d05e9ad478 471 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 167 180 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS05165 9b3f6eb712053797b1e0b6d05e9ad478 471 PANTHER PTHR32071 78 470 1.3E-143 T 22-04-2016 HRM2_RS05165 9b3f6eb712053797b1e0b6d05e9ad478 471 Gene3D G3DSA:1.10.8.60 316 391 1.4E-25 T 22-04-2016 HRM2_RS05165 9b3f6eb712053797b1e0b6d05e9ad478 471 Gene3D G3DSA:1.10.10.60 417 465 2.3E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS05165 9b3f6eb712053797b1e0b6d05e9ad478 471 Pfam PF00158 Sigma-54 interaction domain 145 309 2.1E-66 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS05165 9b3f6eb712053797b1e0b6d05e9ad478 471 Pfam PF02954 Bacterial regulatory protein, Fis family 424 462 4.0E-9 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS05165 9b3f6eb712053797b1e0b6d05e9ad478 471 Gene3D G3DSA:3.40.50.300 141 315 2.4E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05165 9b3f6eb712053797b1e0b6d05e9ad478 471 SUPERFAMILY SSF46689 356 465 2.87E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS05165 9b3f6eb712053797b1e0b6d05e9ad478 471 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 356 365 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS06405 6eee46ad2d695dedf22feb1f7b080945 338 Pfam PF00005 ABC transporter 25 182 7.8E-28 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS06405 6eee46ad2d695dedf22feb1f7b080945 338 Gene3D G3DSA:3.40.50.300 3 256 1.0E-73 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06405 6eee46ad2d695dedf22feb1f7b080945 338 PANTHER PTHR24220 6 319 7.5E-142 T 22-04-2016 HRM2_RS06405 6eee46ad2d695dedf22feb1f7b080945 338 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 319 1.4E-19 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HRM2_RS06405 6eee46ad2d695dedf22feb1f7b080945 338 SUPERFAMILY SSF52540 4 253 2.55E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06405 6eee46ad2d695dedf22feb1f7b080945 338 PANTHER PTHR24220:SF535 6 319 7.5E-142 T 22-04-2016 HRM2_RS06405 6eee46ad2d695dedf22feb1f7b080945 338 SMART SM00382 33 240 8.0E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS06405 6eee46ad2d695dedf22feb1f7b080945 338 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 300 5.0E-15 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HRM2_RS10285 b8dc018a371c471819717cd8e25ea22e 459 SUPERFAMILY SSF53098 64 439 8.34E-40 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS10285 b8dc018a371c471819717cd8e25ea22e 459 Pfam PF13546 DDE superfamily endonuclease 66 255 7.1E-14 T 22-04-2016 HRM2_RS10285 b8dc018a371c471819717cd8e25ea22e 459 Gene3D G3DSA:3.90.350.10 311 349 1.3E-4 T 22-04-2016 IPR014736 Transposase, Tn5-like, core HRM2_RS08595 b8dc018a371c471819717cd8e25ea22e 459 SUPERFAMILY SSF53098 64 439 8.34E-40 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS08595 b8dc018a371c471819717cd8e25ea22e 459 Pfam PF13546 DDE superfamily endonuclease 66 255 7.1E-14 T 22-04-2016 HRM2_RS08595 b8dc018a371c471819717cd8e25ea22e 459 Gene3D G3DSA:3.90.350.10 311 349 1.3E-4 T 22-04-2016 IPR014736 Transposase, Tn5-like, core HRM2_RS14890 1349a8a0da6d68a03e6a9502f1369cf9 465 Pfam PF11104 Type IV pilus assembly protein PilM; 8 167 2.7E-9 T 22-04-2016 IPR005883 Type IV pilus assembly protein PilM HRM2_RS14890 1349a8a0da6d68a03e6a9502f1369cf9 465 SUPERFAMILY SSF53067 61 159 1.19E-9 T 22-04-2016 HRM2_RS14890 1349a8a0da6d68a03e6a9502f1369cf9 465 Pfam PF05137 Fimbrial assembly protein (PilN) 392 462 1.7E-10 T 22-04-2016 IPR007813 Fimbrial assembly PilN HRM2_RS19805 d926f11cb5f38dd5097140a207b09172 1062 PRINTS PR00702 Acriflavin resistance protein family signature 337 360 4.8E-100 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS19805 d926f11cb5f38dd5097140a207b09172 1062 PRINTS PR00702 Acriflavin resistance protein family signature 364 385 4.8E-100 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS19805 d926f11cb5f38dd5097140a207b09172 1062 PRINTS PR00702 Acriflavin resistance protein family signature 560 577 4.8E-100 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS19805 d926f11cb5f38dd5097140a207b09172 1062 PRINTS PR00702 Acriflavin resistance protein family signature 629 643 4.8E-100 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS19805 d926f11cb5f38dd5097140a207b09172 1062 PRINTS PR00702 Acriflavin resistance protein family signature 392 416 4.8E-100 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS19805 d926f11cb5f38dd5097140a207b09172 1062 PRINTS PR00702 Acriflavin resistance protein family signature 9 33 4.8E-100 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS19805 d926f11cb5f38dd5097140a207b09172 1062 PRINTS PR00702 Acriflavin resistance protein family signature 471 494 4.8E-100 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS19805 d926f11cb5f38dd5097140a207b09172 1062 PRINTS PR00702 Acriflavin resistance protein family signature 446 469 4.8E-100 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS19805 d926f11cb5f38dd5097140a207b09172 1062 PRINTS PR00702 Acriflavin resistance protein family signature 37 55 4.8E-100 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS19805 d926f11cb5f38dd5097140a207b09172 1062 Gene3D G3DSA:1.10.3850.10 822 1033 5.2E-51 T 22-04-2016 HRM2_RS19805 d926f11cb5f38dd5097140a207b09172 1062 Gene3D G3DSA:1.10.3850.10 281 499 4.7E-57 T 22-04-2016 HRM2_RS19805 d926f11cb5f38dd5097140a207b09172 1062 SUPERFAMILY SSF82714 730 816 7.46E-20 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS19805 d926f11cb5f38dd5097140a207b09172 1062 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 2 1051 0.0 T 22-04-2016 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 HRM2_RS19805 d926f11cb5f38dd5097140a207b09172 1062 Gene3D G3DSA:3.30.2090.10 182 274 1.9E-22 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS19805 d926f11cb5f38dd5097140a207b09172 1062 Gene3D G3DSA:3.30.70.1430 575 677 2.6E-34 T 22-04-2016 HRM2_RS19805 d926f11cb5f38dd5097140a207b09172 1062 SUPERFAMILY SSF82714 183 273 6.93E-20 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS19805 d926f11cb5f38dd5097140a207b09172 1062 Gene3D G3DSA:3.30.2090.10 730 815 9.7E-23 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS19805 d926f11cb5f38dd5097140a207b09172 1062 SUPERFAMILY SSF82693 573 677 3.4E-30 T 22-04-2016 HRM2_RS19805 d926f11cb5f38dd5097140a207b09172 1062 PANTHER PTHR32063 1 1046 0.0 T 22-04-2016 HRM2_RS19805 d926f11cb5f38dd5097140a207b09172 1062 SUPERFAMILY SSF82866 816 1035 2.49E-40 T 22-04-2016 HRM2_RS19805 d926f11cb5f38dd5097140a207b09172 1062 PANTHER PTHR32063:SF13 1 1046 0.0 T 22-04-2016 HRM2_RS19805 d926f11cb5f38dd5097140a207b09172 1062 SUPERFAMILY SSF82866 297 498 8.24E-48 T 22-04-2016 HRM2_RS19805 d926f11cb5f38dd5097140a207b09172 1062 SUPERFAMILY SSF82693 275 331 5.76E-26 T 22-04-2016 HRM2_RS19805 d926f11cb5f38dd5097140a207b09172 1062 SUPERFAMILY SSF82693 137 183 5.76E-26 T 22-04-2016 HRM2_RS19805 d926f11cb5f38dd5097140a207b09172 1062 SUPERFAMILY SSF82693 39 130 9.42E-23 T 22-04-2016 HRM2_RS19805 d926f11cb5f38dd5097140a207b09172 1062 Gene3D G3DSA:3.30.70.1430 39 140 1.5E-29 T 22-04-2016 HRM2_RS19805 d926f11cb5f38dd5097140a207b09172 1062 Pfam PF00873 AcrB/AcrD/AcrF family 3 1033 0.0 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS08310 9e284846f839cb4eaf3a676aab4109c1 293 Gene3D G3DSA:3.20.20.220 10 287 2.4E-89 T 22-04-2016 IPR029041 FAD-linked oxidoreductase-like HRM2_RS08310 9e284846f839cb4eaf3a676aab4109c1 293 PANTHER PTHR21091:SF31 144 280 8.6E-36 T 22-04-2016 HRM2_RS08310 9e284846f839cb4eaf3a676aab4109c1 293 SUPERFAMILY SSF51730 9 287 1.37E-79 T 22-04-2016 IPR029041 FAD-linked oxidoreductase-like HRM2_RS08310 9e284846f839cb4eaf3a676aab4109c1 293 Pfam PF02219 Methylenetetrahydrofolate reductase 10 286 3.3E-76 T 22-04-2016 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 HRM2_RS08310 9e284846f839cb4eaf3a676aab4109c1 293 PANTHER PTHR21091 144 280 8.6E-36 T 22-04-2016 HRM2_RS11420 7956f22e02ca02062e26703d15837a4f 223 SUPERFAMILY SSF161098 15 206 3.53E-45 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS11420 7956f22e02ca02062e26703d15837a4f 223 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 112 2.5E-25 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HRM2_RS11420 7956f22e02ca02062e26703d15837a4f 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 215 4.2E-19 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS11420 7956f22e02ca02062e26703d15837a4f 223 Gene3D G3DSA:1.10.3720.10 15 217 4.7E-47 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS11420 7956f22e02ca02062e26703d15837a4f 223 PANTHER PTHR30614 1 223 2.4E-91 T 22-04-2016 HRM2_RS17910 0fa1ec2839a9077b1d47f649052f6215 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 204 1.0E-60 T 22-04-2016 HRM2_RS17910 0fa1ec2839a9077b1d47f649052f6215 397 Gene3D G3DSA:2.40.30.10 303 396 2.2E-44 T 22-04-2016 HRM2_RS17910 0fa1ec2839a9077b1d47f649052f6215 397 PANTHER PTHR23115:SF112 1 396 1.8E-243 T 22-04-2016 HRM2_RS17910 0fa1ec2839a9077b1d47f649052f6215 397 Pfam PF03144 Elongation factor Tu domain 2 228 296 1.8E-13 T 22-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 HRM2_RS17910 0fa1ec2839a9077b1d47f649052f6215 397 SUPERFAMILY SSF50465 305 396 8.06E-35 T 22-04-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal HRM2_RS17910 0fa1ec2839a9077b1d47f649052f6215 397 SUPERFAMILY SSF50447 208 304 3.14E-29 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain HRM2_RS17910 0fa1ec2839a9077b1d47f649052f6215 397 Pfam PF03143 Elongation factor Tu C-terminal domain 301 395 4.7E-32 T 22-04-2016 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal HRM2_RS17910 0fa1ec2839a9077b1d47f649052f6215 397 Gene3D G3DSA:2.40.30.10 215 301 3.8E-34 T 22-04-2016 HRM2_RS17910 0fa1ec2839a9077b1d47f649052f6215 397 Gene3D G3DSA:3.40.50.300 4 214 5.2E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17910 0fa1ec2839a9077b1d47f649052f6215 397 PRINTS PR00315 GTP-binding elongation factor signature 78 88 4.2E-25 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS17910 0fa1ec2839a9077b1d47f649052f6215 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 4.2E-25 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS17910 0fa1ec2839a9077b1d47f649052f6215 397 PRINTS PR00315 GTP-binding elongation factor signature 94 105 4.2E-25 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS17910 0fa1ec2839a9077b1d47f649052f6215 397 PRINTS PR00315 GTP-binding elongation factor signature 131 140 4.2E-25 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS17910 0fa1ec2839a9077b1d47f649052f6215 397 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.2E-25 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS17910 0fa1ec2839a9077b1d47f649052f6215 397 PANTHER PTHR23115 1 396 1.8E-243 T 22-04-2016 HRM2_RS17910 0fa1ec2839a9077b1d47f649052f6215 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 6.1E-222 T 22-04-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 HRM2_RS17910 0fa1ec2839a9077b1d47f649052f6215 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 22-04-2016 IPR031157 Tr-type G domain, conserved site HRM2_RS17910 0fa1ec2839a9077b1d47f649052f6215 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 153 1.2E-16 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HRM2_RS17910 0fa1ec2839a9077b1d47f649052f6215 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 59.856 T 22-04-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 HRM2_RS17910 0fa1ec2839a9077b1d47f649052f6215 397 SUPERFAMILY SSF52540 3 217 1.0E-63 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12370 0f41a22fd85e6fde80cacb42cb933f93 207 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 10 203 26.451 T 22-04-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 HRM2_RS12370 0f41a22fd85e6fde80cacb42cb933f93 207 Pfam PF02527 rRNA small subunit methyltransferase G 23 177 6.2E-45 T 22-04-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 HRM2_RS12370 0f41a22fd85e6fde80cacb42cb933f93 207 SUPERFAMILY SSF53335 9 205 2.01E-36 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS12370 0f41a22fd85e6fde80cacb42cb933f93 207 PANTHER PTHR31760:SF0 1 175 9.5E-58 T 22-04-2016 HRM2_RS12370 0f41a22fd85e6fde80cacb42cb933f93 207 PIRSF PIRSF003078 2 206 4.3E-46 T 22-04-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 HRM2_RS12370 0f41a22fd85e6fde80cacb42cb933f93 207 Gene3D G3DSA:3.40.50.150 3 206 2.5E-59 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS12370 0f41a22fd85e6fde80cacb42cb933f93 207 PANTHER PTHR31760 1 175 9.5E-58 T 22-04-2016 HRM2_RS12370 0f41a22fd85e6fde80cacb42cb933f93 207 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 26 178 1.4E-43 T 22-04-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 HRM2_RS03230 3b56a0cb3788755a0d37fe8fac055c53 383 SMART SM00393 290 369 1.9E-9 T 22-04-2016 IPR001374 R3H domain GO:0003676 HRM2_RS03230 3b56a0cb3788755a0d37fe8fac055c53 383 Gene3D G3DSA:3.30.30.80 2 56 6.4E-19 T 22-04-2016 IPR032782 Jag, N-terminal HRM2_RS03230 3b56a0cb3788755a0d37fe8fac055c53 383 Pfam PF13083 KH domain 244 297 6.7E-12 T 22-04-2016 HRM2_RS03230 3b56a0cb3788755a0d37fe8fac055c53 383 SUPERFAMILY SSF82708 315 369 3.92E-6 T 22-04-2016 IPR001374 R3H domain GO:0003676 HRM2_RS03230 3b56a0cb3788755a0d37fe8fac055c53 383 Pfam PF14804 Jag N-terminus 7 56 2.4E-19 T 22-04-2016 IPR032782 Jag, N-terminal HRM2_RS03230 3b56a0cb3788755a0d37fe8fac055c53 383 PANTHER PTHR35800 3 57 2.1E-42 T 22-04-2016 HRM2_RS03230 3b56a0cb3788755a0d37fe8fac055c53 383 PANTHER PTHR35800 219 372 2.1E-42 T 22-04-2016 HRM2_RS03230 3b56a0cb3788755a0d37fe8fac055c53 383 Pfam PF01424 R3H domain 310 368 7.8E-9 T 22-04-2016 IPR001374 R3H domain GO:0003676 HRM2_RS03230 3b56a0cb3788755a0d37fe8fac055c53 383 Gene3D G3DSA:3.30.300.120 227 300 2.9E-17 T 22-04-2016 HRM2_RS03230 3b56a0cb3788755a0d37fe8fac055c53 383 SMART SM01245 6 58 9.6E-23 T 22-04-2016 IPR032782 Jag, N-terminal HRM2_RS03230 3b56a0cb3788755a0d37fe8fac055c53 383 Gene3D G3DSA:3.30.1370.50 301 373 8.4E-23 T 22-04-2016 IPR001374 R3H domain GO:0003676 HRM2_RS05080 5e4d1cf1fc33249684d7f123870a892a 449 Pfam PF00206 Lyase 12 341 3.7E-100 T 22-04-2016 IPR022761 Fumarate lyase, N-terminal HRM2_RS05080 5e4d1cf1fc33249684d7f123870a892a 449 PRINTS PR00149 Fumarate lyase superfamily signature 270 297 3.7E-33 T 22-04-2016 IPR000362 Fumarate lyase family HRM2_RS05080 5e4d1cf1fc33249684d7f123870a892a 449 PRINTS PR00149 Fumarate lyase superfamily signature 179 197 3.7E-33 T 22-04-2016 IPR000362 Fumarate lyase family HRM2_RS05080 5e4d1cf1fc33249684d7f123870a892a 449 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 3.7E-33 T 22-04-2016 IPR000362 Fumarate lyase family HRM2_RS05080 5e4d1cf1fc33249684d7f123870a892a 449 PRINTS PR00149 Fumarate lyase superfamily signature 316 332 3.7E-33 T 22-04-2016 IPR000362 Fumarate lyase family HRM2_RS05080 5e4d1cf1fc33249684d7f123870a892a 449 PRINTS PR00145 Argininosuccinate lyase family signature 132 154 2.2E-5 T 22-04-2016 HRM2_RS05080 5e4d1cf1fc33249684d7f123870a892a 449 PRINTS PR00145 Argininosuccinate lyase family signature 316 332 2.2E-5 T 22-04-2016 HRM2_RS05080 5e4d1cf1fc33249684d7f123870a892a 449 PRINTS PR00145 Argininosuccinate lyase family signature 174 194 2.2E-5 T 22-04-2016 HRM2_RS05080 5e4d1cf1fc33249684d7f123870a892a 449 PANTHER PTHR11444:SF1 1 441 4.7E-197 T 22-04-2016 HRM2_RS05080 5e4d1cf1fc33249684d7f123870a892a 449 Hamap MF_00743 Fumarate hydratase class II [fumC]. 3 449 72.581 T 22-04-2016 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS05080 5e4d1cf1fc33249684d7f123870a892a 449 SUPERFAMILY SSF48557 3 440 5.97E-140 T 22-04-2016 IPR008948 L-Aspartase-like GO:0003824 HRM2_RS05080 5e4d1cf1fc33249684d7f123870a892a 449 Gene3D G3DSA:1.10.40.30 408 443 1.3E-13 T 22-04-2016 HRM2_RS05080 5e4d1cf1fc33249684d7f123870a892a 449 Pfam PF10415 Fumarase C C-terminus 408 443 3.7E-12 T 22-04-2016 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS05080 5e4d1cf1fc33249684d7f123870a892a 449 Gene3D G3DSA:1.20.200.10 138 402 2.8E-92 T 22-04-2016 HRM2_RS05080 5e4d1cf1fc33249684d7f123870a892a 449 PANTHER PTHR11444 1 441 4.7E-197 T 22-04-2016 IPR000362 Fumarate lyase family HRM2_RS05080 5e4d1cf1fc33249684d7f123870a892a 449 ProSitePatterns PS00163 Fumarate lyases signature. 316 325 - T 22-04-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 HRM2_RS05080 5e4d1cf1fc33249684d7f123870a892a 449 Gene3D G3DSA:1.10.275.10 1 137 1.2E-54 T 22-04-2016 IPR024083 Fumarase/histidase, N-terminal HRM2_RS06540 6ec5667677bb631c9ed498c835df0bcd 143 Pfam PF06841 T4-like virus tail tube protein gp19 9 139 4.6E-43 T 22-04-2016 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 HRM2_RS06540 6ec5667677bb631c9ed498c835df0bcd 143 PANTHER PTHR38009 1 142 5.6E-27 T 22-04-2016 HRM2_RS06540 6ec5667677bb631c9ed498c835df0bcd 143 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 4 140 1.1E-39 T 22-04-2016 IPR011747 Conserved hypothetical protein CHP02241 HRM2_RS06540 6ec5667677bb631c9ed498c835df0bcd 143 PANTHER PTHR38009:SF1 1 142 5.6E-27 T 22-04-2016 HRM2_RS15580 e91c8c7ebf10adbdd7d8876347ef86fe 555 PANTHER PTHR11956:SF6 1 555 4.2E-212 T 22-04-2016 HRM2_RS15580 e91c8c7ebf10adbdd7d8876347ef86fe 555 SMART SM01016 3 91 2.9E-24 T 22-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 HRM2_RS15580 e91c8c7ebf10adbdd7d8876347ef86fe 555 PANTHER PTHR11956 1 555 4.2E-212 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 HRM2_RS15580 e91c8c7ebf10adbdd7d8876347ef86fe 555 Gene3D G3DSA:3.30.1360.70 3 109 2.5E-26 T 22-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 HRM2_RS15580 e91c8c7ebf10adbdd7d8876347ef86fe 555 Hamap MF_00123 Arginine--tRNA ligase [argS]. 7 555 26.281 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 HRM2_RS15580 e91c8c7ebf10adbdd7d8876347ef86fe 555 PRINTS PR01038 Arginyl-tRNA synthetase signature 159 172 4.9E-24 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 HRM2_RS15580 e91c8c7ebf10adbdd7d8876347ef86fe 555 PRINTS PR01038 Arginyl-tRNA synthetase signature 120 135 4.9E-24 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 HRM2_RS15580 e91c8c7ebf10adbdd7d8876347ef86fe 555 PRINTS PR01038 Arginyl-tRNA synthetase signature 135 151 4.9E-24 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 HRM2_RS15580 e91c8c7ebf10adbdd7d8876347ef86fe 555 PRINTS PR01038 Arginyl-tRNA synthetase signature 302 323 4.9E-24 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 HRM2_RS15580 e91c8c7ebf10adbdd7d8876347ef86fe 555 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 31 555 5.3E-137 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 HRM2_RS15580 e91c8c7ebf10adbdd7d8876347ef86fe 555 Pfam PF00750 tRNA synthetases class I (R) 112 402 1.9E-26 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 HRM2_RS15580 e91c8c7ebf10adbdd7d8876347ef86fe 555 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 24 91 1.7E-19 T 22-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 HRM2_RS15580 e91c8c7ebf10adbdd7d8876347ef86fe 555 SUPERFAMILY SSF55190 24 111 7.32E-21 T 22-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 HRM2_RS15580 e91c8c7ebf10adbdd7d8876347ef86fe 555 Pfam PF05746 DALR anticodon binding domain 433 555 6.3E-31 T 22-04-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 HRM2_RS15580 e91c8c7ebf10adbdd7d8876347ef86fe 555 SUPERFAMILY SSF47323 427 555 7.85E-34 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS15580 e91c8c7ebf10adbdd7d8876347ef86fe 555 Gene3D G3DSA:3.40.50.620 114 436 1.7E-105 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS15580 e91c8c7ebf10adbdd7d8876347ef86fe 555 Gene3D G3DSA:1.10.730.10 437 555 1.1E-38 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS15580 e91c8c7ebf10adbdd7d8876347ef86fe 555 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 130 139 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS15580 e91c8c7ebf10adbdd7d8876347ef86fe 555 SUPERFAMILY SSF52374 114 442 3.38E-89 T 22-04-2016 HRM2_RS15580 e91c8c7ebf10adbdd7d8876347ef86fe 555 SMART SM00836 433 555 1.3E-45 T 22-04-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 HRM2_RS16050 fb9a5362bff1d66a7e0b2d367d23a355 450 Gene3D G3DSA:1.10.510.10 128 225 1.9E-34 T 22-04-2016 HRM2_RS16050 fb9a5362bff1d66a7e0b2d367d23a355 450 SUPERFAMILY SSF56112 3 266 1.2E-54 T 22-04-2016 IPR011009 Protein kinase-like domain HRM2_RS16050 fb9a5362bff1d66a7e0b2d367d23a355 450 SMART SM00220 7 268 9.9E-39 T 22-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 HRM2_RS16050 fb9a5362bff1d66a7e0b2d367d23a355 450 Gene3D G3DSA:3.30.200.20 3 127 1.8E-17 T 22-04-2016 HRM2_RS16050 fb9a5362bff1d66a7e0b2d367d23a355 450 PANTHER PTHR24362 4 261 1.2E-55 T 22-04-2016 HRM2_RS16050 fb9a5362bff1d66a7e0b2d367d23a355 450 Pfam PF00069 Protein kinase domain 8 231 4.1E-35 T 22-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 HRM2_RS16050 fb9a5362bff1d66a7e0b2d367d23a355 450 Pfam PF07603 Protein of unknown function (DUF1566) 333 444 1.2E-15 T 22-04-2016 IPR011460 Protein of unknown function DUF1566 HRM2_RS16050 fb9a5362bff1d66a7e0b2d367d23a355 450 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 137 149 - T 22-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 HRM2_RS16050 fb9a5362bff1d66a7e0b2d367d23a355 450 PANTHER PTHR24362:SF160 4 261 1.2E-55 T 22-04-2016 HRM2_RS08130 4fbe6e8f0b1f0905031968ddf09c4247 253 Pfam PF01618 MotA/TolQ/ExbB proton channel family 104 217 3.6E-22 T 22-04-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 HRM2_RS08130 4fbe6e8f0b1f0905031968ddf09c4247 253 PANTHER PTHR30433:SF2 2 244 2.0E-105 T 22-04-2016 IPR022522 Flagellar motor stator, MotA HRM2_RS08130 4fbe6e8f0b1f0905031968ddf09c4247 253 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 184 201 - T 22-04-2016 IPR000540 Flagellar motor protein MotA, conserved site HRM2_RS08130 4fbe6e8f0b1f0905031968ddf09c4247 253 PANTHER PTHR30433 2 244 2.0E-105 T 22-04-2016 HRM2_RS16460 6ceb00fc078caf1b6f5e40715afaa186 356 Pfam PF04632 Fusaric acid resistance protein family 15 196 2.0E-29 T 22-04-2016 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0006810 HRM2_RS16460 6ceb00fc078caf1b6f5e40715afaa186 356 PANTHER PTHR30509 10 189 3.0E-29 T 22-04-2016 HRM2_RS21525 e37d98f24de4bdbb781d4ddc6b633366 300 SMART SM00062 44 278 4.6E-55 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS21525 e37d98f24de4bdbb781d4ddc6b633366 300 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 46 276 1.9E-48 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS21525 e37d98f24de4bdbb781d4ddc6b633366 300 Gene3D G3DSA:3.40.190.10 128 238 1.5E-23 T 22-04-2016 HRM2_RS21525 e37d98f24de4bdbb781d4ddc6b633366 300 PANTHER PTHR30085 14 294 6.9E-58 T 22-04-2016 HRM2_RS21525 e37d98f24de4bdbb781d4ddc6b633366 300 SMART SM00079 46 277 1.1E-4 T 22-04-2016 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 HRM2_RS21525 e37d98f24de4bdbb781d4ddc6b633366 300 Gene3D G3DSA:3.40.190.10 239 278 1.8E-28 T 22-04-2016 HRM2_RS21525 e37d98f24de4bdbb781d4ddc6b633366 300 Gene3D G3DSA:3.40.190.10 41 127 1.8E-28 T 22-04-2016 HRM2_RS21525 e37d98f24de4bdbb781d4ddc6b633366 300 SUPERFAMILY SSF53850 34 278 1.25E-58 T 22-04-2016 HRM2_RS21525 e37d98f24de4bdbb781d4ddc6b633366 300 PANTHER PTHR30085:SF2 14 294 6.9E-58 T 22-04-2016 HRM2_RS21650 1ae4ea5286348f7f0f9f697f64f05bca 160 PANTHER PTHR31964:SF26 5 148 1.2E-29 T 22-04-2016 HRM2_RS21650 1ae4ea5286348f7f0f9f697f64f05bca 160 PRINTS PR01438 Universal stress protein signature 4 22 5.5E-15 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS21650 1ae4ea5286348f7f0f9f697f64f05bca 160 PRINTS PR01438 Universal stress protein signature 103 115 5.5E-15 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS21650 1ae4ea5286348f7f0f9f697f64f05bca 160 PRINTS PR01438 Universal stress protein signature 121 143 5.5E-15 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS21650 1ae4ea5286348f7f0f9f697f64f05bca 160 SUPERFAMILY SSF52402 4 146 9.21E-37 T 22-04-2016 HRM2_RS21650 1ae4ea5286348f7f0f9f697f64f05bca 160 Gene3D G3DSA:3.40.50.620 3 145 2.1E-36 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS21650 1ae4ea5286348f7f0f9f697f64f05bca 160 Pfam PF00582 Universal stress protein family 4 143 8.9E-29 T 22-04-2016 IPR006016 UspA GO:0006950 HRM2_RS21650 1ae4ea5286348f7f0f9f697f64f05bca 160 PANTHER PTHR31964 5 148 1.2E-29 T 22-04-2016 HRM2_RS09175 6ad770de190206206d842aef39daac59 403 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 329 335 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HRM2_RS09175 6ad770de190206206d842aef39daac59 403 PANTHER PTHR14911 47 242 5.6E-52 T 22-04-2016 HRM2_RS09175 6ad770de190206206d842aef39daac59 403 PANTHER PTHR14911 282 367 5.6E-52 T 22-04-2016 HRM2_RS09175 6ad770de190206206d842aef39daac59 403 Pfam PF01170 Putative RNA methylase family UPF0020 192 397 2.4E-41 T 22-04-2016 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HRM2_RS09175 6ad770de190206206d842aef39daac59 403 Gene3D G3DSA:3.40.50.150 282 386 4.6E-22 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS09175 6ad770de190206206d842aef39daac59 403 Gene3D G3DSA:3.40.50.150 174 244 4.6E-22 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS09175 6ad770de190206206d842aef39daac59 403 PANTHER PTHR14911:SF13 47 242 5.6E-52 T 22-04-2016 HRM2_RS09175 6ad770de190206206d842aef39daac59 403 PANTHER PTHR14911:SF13 282 367 5.6E-52 T 22-04-2016 HRM2_RS09175 6ad770de190206206d842aef39daac59 403 SMART SM00981 86 184 5.9E-21 T 22-04-2016 IPR004114 THUMP domain GO:0003723 HRM2_RS09175 6ad770de190206206d842aef39daac59 403 SUPERFAMILY SSF53335 170 247 3.94E-39 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS09175 6ad770de190206206d842aef39daac59 403 SUPERFAMILY SSF53335 285 401 3.94E-39 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS09175 6ad770de190206206d842aef39daac59 403 Pfam PF02926 THUMP domain 46 183 5.8E-17 T 22-04-2016 IPR004114 THUMP domain GO:0003723 HRM2_RS11835 687a81862686726e74be39d065fdad61 273 Pfam PF00037 4Fe-4S binding domain 165 187 2.6E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS11835 687a81862686726e74be39d065fdad61 273 Gene3D G3DSA:1.10.1060.10 176 220 3.4E-7 T 22-04-2016 HRM2_RS11835 687a81862686726e74be39d065fdad61 273 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 8 191 7.1E-25 T 22-04-2016 IPR010207 Electron transport complex, RnfB/RsxB GO:0009055|GO:0051536 HRM2_RS11835 687a81862686726e74be39d065fdad61 273 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 216 266 1.8E-6 T 22-04-2016 HRM2_RS11835 687a81862686726e74be39d065fdad61 273 SUPERFAMILY SSF54862 142 226 1.26E-15 T 22-04-2016 HRM2_RS11835 687a81862686726e74be39d065fdad61 273 Pfam PF04060 Putative Fe-S cluster 46 78 4.9E-13 T 22-04-2016 IPR007202 4Fe-4S domain GO:0051536 HRM2_RS11835 687a81862686726e74be39d065fdad61 273 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 171 182 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS11835 687a81862686726e74be39d065fdad61 273 Gene3D G3DSA:3.30.70.20 221 265 3.4E-7 T 22-04-2016 HRM2_RS11835 687a81862686726e74be39d065fdad61 273 Gene3D G3DSA:3.30.70.20 142 175 5.1E-13 T 22-04-2016 HRM2_RS14010 03eda127b27f6d34912ddd107b208272 716 Pfam PF02754 Cysteine-rich domain 477 560 4.0E-13 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS14010 03eda127b27f6d34912ddd107b208272 716 Pfam PF02754 Cysteine-rich domain 609 692 2.1E-17 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS14010 03eda127b27f6d34912ddd107b208272 716 Gene3D G3DSA:1.10.1060.10 310 398 3.7E-14 T 22-04-2016 HRM2_RS14010 03eda127b27f6d34912ddd107b208272 716 Pfam PF13183 4Fe-4S dicluster domain 311 378 3.0E-9 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS14010 03eda127b27f6d34912ddd107b208272 716 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 314 325 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS14010 03eda127b27f6d34912ddd107b208272 716 PANTHER PTHR32479 58 468 1.5E-114 T 22-04-2016 HRM2_RS14010 03eda127b27f6d34912ddd107b208272 716 Pfam PF02589 Uncharacterised ACR, YkgG family COG1556 70 294 3.8E-52 T 22-04-2016 IPR003741 LUD domain HRM2_RS14010 03eda127b27f6d34912ddd107b208272 716 SUPERFAMILY SSF54862 292 393 1.38E-14 T 22-04-2016 HRM2_RS14010 03eda127b27f6d34912ddd107b208272 716 SUPERFAMILY SSF100950 134 296 9.21E-39 T 22-04-2016 HRM2_RS14010 03eda127b27f6d34912ddd107b208272 716 SUPERFAMILY SSF100950 64 88 9.21E-39 T 22-04-2016 HRM2_RS14010 03eda127b27f6d34912ddd107b208272 716 PANTHER PTHR32479:SF10 58 468 1.5E-114 T 22-04-2016 HRM2_RS14010 03eda127b27f6d34912ddd107b208272 716 Gene3D G3DSA:3.40.50.10420 64 127 8.1E-45 T 22-04-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain HRM2_RS14010 03eda127b27f6d34912ddd107b208272 716 Gene3D G3DSA:3.40.50.10420 189 295 8.1E-45 T 22-04-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain HRM2_RS08325 a2c0ddcd450ff9b4ca8fd139db9f9295 261 PANTHER PTHR13696:SF73 5 261 1.4E-46 T 22-04-2016 HRM2_RS08325 a2c0ddcd450ff9b4ca8fd139db9f9295 261 SUPERFAMILY SSF52540 1 254 2.6E-35 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08325 a2c0ddcd450ff9b4ca8fd139db9f9295 261 PANTHER PTHR13696 5 261 1.4E-46 T 22-04-2016 HRM2_RS08325 a2c0ddcd450ff9b4ca8fd139db9f9295 261 PIRSF PIRSF005647 3 254 2.2E-60 T 22-04-2016 IPR014433 Nickel insertion ATPase/GTPase (CO dehydrogenase maturation factor), CooC type HRM2_RS08325 a2c0ddcd450ff9b4ca8fd139db9f9295 261 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 216 4.7E-20 T 22-04-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain HRM2_RS08325 a2c0ddcd450ff9b4ca8fd139db9f9295 261 Gene3D G3DSA:3.40.50.300 1 250 4.4E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14495 b8a730e5127ba58c522094feb9634879 434 Gene3D G3DSA:3.30.1340.10 336 417 8.8E-6 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like HRM2_RS14495 b8a730e5127ba58c522094feb9634879 434 SUPERFAMILY SSF55594 336 387 2.09E-6 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like HRM2_RS11535 e77a69c7813708d0f42c94e321304cae 241 PANTHER PTHR24220:SF66 7 223 5.5E-65 T 22-04-2016 HRM2_RS11535 e77a69c7813708d0f42c94e321304cae 241 Pfam PF00005 ABC transporter 23 170 1.1E-28 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS11535 e77a69c7813708d0f42c94e321304cae 241 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS11535 e77a69c7813708d0f42c94e321304cae 241 SMART SM00382 32 215 2.6E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS11535 e77a69c7813708d0f42c94e321304cae 241 Gene3D G3DSA:3.40.50.300 4 223 2.0E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11535 e77a69c7813708d0f42c94e321304cae 241 PANTHER PTHR24220 7 223 5.5E-65 T 22-04-2016 HRM2_RS11535 e77a69c7813708d0f42c94e321304cae 241 SUPERFAMILY SSF52540 4 222 1.82E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13415 df708ad08e4bdf2ab16d36d47867928e 457 PANTHER PTHR11444:SF17 8 449 2.2E-179 T 22-04-2016 HRM2_RS13415 df708ad08e4bdf2ab16d36d47867928e 457 Gene3D G3DSA:1.10.275.10 7 114 7.8E-34 T 22-04-2016 IPR024083 Fumarase/histidase, N-terminal HRM2_RS13415 df708ad08e4bdf2ab16d36d47867928e 457 Gene3D G3DSA:1.10.40.30 384 441 8.4E-20 T 22-04-2016 HRM2_RS13415 df708ad08e4bdf2ab16d36d47867928e 457 Gene3D G3DSA:1.20.200.10 115 383 3.5E-66 T 22-04-2016 HRM2_RS13415 df708ad08e4bdf2ab16d36d47867928e 457 PRINTS PR00149 Fumarate lyase superfamily signature 112 130 8.4E-7 T 22-04-2016 IPR000362 Fumarate lyase family HRM2_RS13415 df708ad08e4bdf2ab16d36d47867928e 457 PRINTS PR00149 Fumarate lyase superfamily signature 157 175 8.4E-7 T 22-04-2016 IPR000362 Fumarate lyase family HRM2_RS13415 df708ad08e4bdf2ab16d36d47867928e 457 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 11 449 1.5E-104 T 22-04-2016 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 HRM2_RS13415 df708ad08e4bdf2ab16d36d47867928e 457 Pfam PF00206 Lyase 13 307 9.3E-47 T 22-04-2016 IPR022761 Fumarate lyase, N-terminal HRM2_RS13415 df708ad08e4bdf2ab16d36d47867928e 457 Pfam PF08328 Adenylosuccinate lyase C-terminal 326 441 5.5E-38 T 22-04-2016 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 HRM2_RS13415 df708ad08e4bdf2ab16d36d47867928e 457 PANTHER PTHR11444 8 449 2.2E-179 T 22-04-2016 IPR000362 Fumarate lyase family HRM2_RS13415 df708ad08e4bdf2ab16d36d47867928e 457 ProSitePatterns PS00163 Fumarate lyases signature. 289 298 - T 22-04-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 HRM2_RS13415 df708ad08e4bdf2ab16d36d47867928e 457 SUPERFAMILY SSF48557 11 420 4.56E-83 T 22-04-2016 IPR008948 L-Aspartase-like GO:0003824 HRM2_RS11465 61c79fa643d99400def66c3275ef7aef 366 PANTHER PTHR18964 1 361 4.7E-109 T 22-04-2016 HRM2_RS11465 61c79fa643d99400def66c3275ef7aef 366 SUPERFAMILY SSF53756 1 361 3.22E-114 T 22-04-2016 HRM2_RS11465 61c79fa643d99400def66c3275ef7aef 366 Gene3D G3DSA:3.40.50.2000 1 205 3.2E-76 T 22-04-2016 HRM2_RS11465 61c79fa643d99400def66c3275ef7aef 366 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 361 5.2E-97 T 22-04-2016 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 KEGG: 00520+5.1.3.14|MetaCyc: PWY-7335 HRM2_RS11465 61c79fa643d99400def66c3275ef7aef 366 PANTHER PTHR18964:SF70 1 361 4.7E-109 T 22-04-2016 HRM2_RS11465 61c79fa643d99400def66c3275ef7aef 366 Gene3D G3DSA:3.40.50.2000 206 360 1.2E-50 T 22-04-2016 HRM2_RS11465 61c79fa643d99400def66c3275ef7aef 366 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 22 359 2.0E-113 T 22-04-2016 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain HRM2_RS02990 748a67fe8da99f8de00ef7220464ed73 292 Gene3D G3DSA:3.10.129.10 10 120 3.2E-47 T 22-04-2016 IPR029069 HotDog domain HRM2_RS02990 748a67fe8da99f8de00ef7220464ed73 292 Pfam PF13622 Thioesterase-like superfamily 38 287 3.1E-56 T 22-04-2016 HRM2_RS02990 748a67fe8da99f8de00ef7220464ed73 292 TIGRFAM TIGR00189 tesB: acyl-CoA thioesterase II 17 288 6.7E-93 T 22-04-2016 IPR003703 Acyl-CoA thioesterase GO:0006637|GO:0047617 HRM2_RS02990 748a67fe8da99f8de00ef7220464ed73 292 SUPERFAMILY SSF54637 10 119 3.59E-39 T 22-04-2016 IPR029069 HotDog domain HRM2_RS02990 748a67fe8da99f8de00ef7220464ed73 292 Gene3D G3DSA:3.10.129.10 130 288 1.5E-52 T 22-04-2016 IPR029069 HotDog domain HRM2_RS02990 748a67fe8da99f8de00ef7220464ed73 292 PANTHER PTHR11066 10 292 6.0E-113 T 22-04-2016 IPR003703 Acyl-CoA thioesterase GO:0006637|GO:0047617 HRM2_RS02990 748a67fe8da99f8de00ef7220464ed73 292 SUPERFAMILY SSF54637 121 289 1.49E-55 T 22-04-2016 IPR029069 HotDog domain HRM2_RS11820 aca78e7598d0ba19f957ddab450b5749 217 PANTHER PTHR36118:SF1 5 208 2.5E-20 T 22-04-2016 HRM2_RS11820 aca78e7598d0ba19f957ddab450b5749 217 PANTHER PTHR36118 5 208 2.5E-20 T 22-04-2016 HRM2_RS11820 aca78e7598d0ba19f957ddab450b5749 217 PIRSF PIRSF006091 2 214 4.3E-32 T 22-04-2016 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 HRM2_RS11820 aca78e7598d0ba19f957ddab450b5749 217 SMART SM00900 110 201 2.2E-21 T 22-04-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 HRM2_RS11820 aca78e7598d0ba19f957ddab450b5749 217 Hamap MF_00479 Electron transport complex subunit RsxG [rsxG]. 5 203 21.086 T 22-04-2016 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 HRM2_RS11820 aca78e7598d0ba19f957ddab450b5749 217 Pfam PF04205 FMN-binding domain 110 198 1.5E-18 T 22-04-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 HRM2_RS00360 4dc42a0f493163241a2d69b25dd80c05 362 Gene3D G3DSA:3.60.10.10 102 256 2.0E-5 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase HRM2_RS00360 4dc42a0f493163241a2d69b25dd80c05 362 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 104 311 6.4E-22 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase HRM2_RS00360 4dc42a0f493163241a2d69b25dd80c05 362 SUPERFAMILY SSF56219 99 319 7.72E-29 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase HRM2_RS04015 79bdf21327208140f895ec8856ea593d 371 Gene3D G3DSA:3.40.640.10 22 264 1.2E-60 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS04015 79bdf21327208140f895ec8856ea593d 371 PANTHER PTHR21152 8 371 1.1E-121 T 22-04-2016 HRM2_RS04015 79bdf21327208140f895ec8856ea593d 371 Gene3D G3DSA:3.90.1150.10 265 370 4.7E-36 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS04015 79bdf21327208140f895ec8856ea593d 371 SUPERFAMILY SSF53383 11 369 2.42E-108 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS04015 79bdf21327208140f895ec8856ea593d 371 Pfam PF00266 Aminotransferase class-V 11 347 2.0E-43 T 22-04-2016 IPR000192 Aminotransferase class V domain HRM2_RS04015 79bdf21327208140f895ec8856ea593d 371 PIRSF PIRSF000524 6 371 1.3E-122 T 22-04-2016 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 HRM2_RS20560 c87d157fcbb97de7999f25043b484fed 373 Pfam PF00534 Glycosyl transferases group 1 202 341 1.1E-30 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 HRM2_RS20560 c87d157fcbb97de7999f25043b484fed 373 SUPERFAMILY SSF53756 24 367 2.15E-58 T 22-04-2016 HRM2_RS20560 c87d157fcbb97de7999f25043b484fed 373 Gene3D G3DSA:3.40.50.2000 155 343 1.0E-26 T 22-04-2016 HRM2_RS20560 c87d157fcbb97de7999f25043b484fed 373 PANTHER PTHR12526 27 368 2.2E-43 T 22-04-2016 HRM2_RS01670 16e7864ff923bf6bb57a9f35d4708618 454 Gene3D G3DSA:3.30.565.10 310 442 1.0E-23 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS01670 16e7864ff923bf6bb57a9f35d4708618 454 Gene3D G3DSA:1.10.287.130 228 300 3.9E-13 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS01670 16e7864ff923bf6bb57a9f35d4708618 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 391 1.5E-6 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS01670 16e7864ff923bf6bb57a9f35d4708618 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 444 1.5E-6 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS01670 16e7864ff923bf6bb57a9f35d4708618 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 425 1.5E-6 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS01670 16e7864ff923bf6bb57a9f35d4708618 454 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 349 441 1.9E-13 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS01670 16e7864ff923bf6bb57a9f35d4708618 454 Pfam PF00512 His Kinase A (phospho-acceptor) domain 238 302 2.6E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS01670 16e7864ff923bf6bb57a9f35d4708618 454 SUPERFAMILY SSF47384 219 302 4.32E-15 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS01670 16e7864ff923bf6bb57a9f35d4708618 454 SUPERFAMILY SSF55874 306 442 3.27E-25 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS01670 16e7864ff923bf6bb57a9f35d4708618 454 Pfam PF00672 HAMP domain 163 231 7.7E-7 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS01670 16e7864ff923bf6bb57a9f35d4708618 454 PANTHER PTHR24423 176 441 1.4E-41 T 22-04-2016 HRM2_RS01670 16e7864ff923bf6bb57a9f35d4708618 454 PANTHER PTHR24423 15 23 1.4E-41 T 22-04-2016 HRM2_RS01670 16e7864ff923bf6bb57a9f35d4708618 454 SMART SM00387 345 447 2.5E-17 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS01670 16e7864ff923bf6bb57a9f35d4708618 454 SMART SM00388 236 304 5.7E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS12435 f796f1acc4de6a7267c20af246fec59b 477 PIRSF PIRSF000350 1 473 1.2E-83 T 22-04-2016 HRM2_RS12435 f796f1acc4de6a7267c20af246fec59b 477 Gene3D G3DSA:3.50.50.60 238 347 6.0E-20 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS12435 f796f1acc4de6a7267c20af246fec59b 477 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 358 465 1.9E-32 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HRM2_RS12435 f796f1acc4de6a7267c20af246fec59b 477 PANTHER PTHR22912 4 470 8.1E-144 T 22-04-2016 HRM2_RS12435 f796f1acc4de6a7267c20af246fec59b 477 Gene3D G3DSA:3.50.50.60 4 138 1.3E-37 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS12435 f796f1acc4de6a7267c20af246fec59b 477 Gene3D G3DSA:3.50.50.60 139 237 1.3E-24 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS12435 f796f1acc4de6a7267c20af246fec59b 477 Gene3D G3DSA:3.30.390.30 348 476 7.6E-43 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HRM2_RS12435 f796f1acc4de6a7267c20af246fec59b 477 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 339 2.7E-62 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS12435 f796f1acc4de6a7267c20af246fec59b 477 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 476 1.0E-140 T 22-04-2016 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084 HRM2_RS12435 f796f1acc4de6a7267c20af246fec59b 477 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 4.3E-33 T 22-04-2016 HRM2_RS12435 f796f1acc4de6a7267c20af246fec59b 477 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 4.3E-33 T 22-04-2016 HRM2_RS12435 f796f1acc4de6a7267c20af246fec59b 477 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 4.3E-33 T 22-04-2016 HRM2_RS12435 f796f1acc4de6a7267c20af246fec59b 477 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 273 289 4.3E-33 T 22-04-2016 HRM2_RS12435 f796f1acc4de6a7267c20af246fec59b 477 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 302 324 4.3E-33 T 22-04-2016 HRM2_RS12435 f796f1acc4de6a7267c20af246fec59b 477 SUPERFAMILY SSF51905 5 348 4.82E-52 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS12435 f796f1acc4de6a7267c20af246fec59b 477 PANTHER PTHR22912:SF125 4 470 8.1E-144 T 22-04-2016 HRM2_RS12435 f796f1acc4de6a7267c20af246fec59b 477 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 317 324 4.5E-69 T 22-04-2016 HRM2_RS12435 f796f1acc4de6a7267c20af246fec59b 477 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 36 51 4.5E-69 T 22-04-2016 HRM2_RS12435 f796f1acc4de6a7267c20af246fec59b 477 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 4.5E-69 T 22-04-2016 HRM2_RS12435 f796f1acc4de6a7267c20af246fec59b 477 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 288 4.5E-69 T 22-04-2016 HRM2_RS12435 f796f1acc4de6a7267c20af246fec59b 477 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 4.5E-69 T 22-04-2016 HRM2_RS12435 f796f1acc4de6a7267c20af246fec59b 477 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 354 375 4.5E-69 T 22-04-2016 HRM2_RS12435 f796f1acc4de6a7267c20af246fec59b 477 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 138 147 4.5E-69 T 22-04-2016 HRM2_RS12435 f796f1acc4de6a7267c20af246fec59b 477 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 419 434 4.5E-69 T 22-04-2016 HRM2_RS12435 f796f1acc4de6a7267c20af246fec59b 477 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 441 461 4.5E-69 T 22-04-2016 HRM2_RS12435 f796f1acc4de6a7267c20af246fec59b 477 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 37 47 - T 22-04-2016 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 HRM2_RS12435 f796f1acc4de6a7267c20af246fec59b 477 SUPERFAMILY SSF55424 355 476 2.06E-38 T 22-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 HRM2_RS09260 f29fa3672c1e31d595dcc01d2d8bf2dc 458 Gene3D G3DSA:1.10.45.10 418 457 1.4E-12 T 22-04-2016 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 HRM2_RS09260 f29fa3672c1e31d595dcc01d2d8bf2dc 458 PANTHER PTHR11748 11 458 3.1E-176 T 22-04-2016 HRM2_RS09260 f29fa3672c1e31d595dcc01d2d8bf2dc 458 Gene3D G3DSA:3.30.43.10 3 96 5.3E-24 T 22-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 HRM2_RS09260 f29fa3672c1e31d595dcc01d2d8bf2dc 458 Pfam PF01565 FAD binding domain 41 180 6.6E-40 T 22-04-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 HRM2_RS09260 f29fa3672c1e31d595dcc01d2d8bf2dc 458 PANTHER PTHR11748:SF85 11 458 3.1E-176 T 22-04-2016 HRM2_RS09260 f29fa3672c1e31d595dcc01d2d8bf2dc 458 Pfam PF02913 FAD linked oxidases, C-terminal domain 216 457 6.9E-70 T 22-04-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 HRM2_RS09260 f29fa3672c1e31d595dcc01d2d8bf2dc 458 Gene3D G3DSA:3.30.465.10 97 217 4.8E-45 T 22-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 HRM2_RS09260 f29fa3672c1e31d595dcc01d2d8bf2dc 458 SUPERFAMILY SSF56176 5 217 1.73E-69 T 22-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 HRM2_RS09260 f29fa3672c1e31d595dcc01d2d8bf2dc 458 SUPERFAMILY SSF55103 220 458 2.62E-70 T 22-04-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 HRM2_RS20165 6d74d42e5d8d8f38750be2cbcd721033 139 PANTHER PTHR33516:SF1 19 139 2.6E-49 T 22-04-2016 HRM2_RS20165 6d74d42e5d8d8f38750be2cbcd721033 139 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 52 62 7.2E-11 T 22-04-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 HRM2_RS20165 6d74d42e5d8d8f38750be2cbcd721033 139 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 63 74 7.2E-11 T 22-04-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 HRM2_RS20165 6d74d42e5d8d8f38750be2cbcd721033 139 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 91 103 7.2E-11 T 22-04-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 HRM2_RS20165 6d74d42e5d8d8f38750be2cbcd721033 139 PANTHER PTHR33516 19 139 2.6E-49 T 22-04-2016 HRM2_RS20165 6d74d42e5d8d8f38750be2cbcd721033 139 Pfam PF00717 Peptidase S24-like 55 122 4.5E-12 T 22-04-2016 IPR019759 Peptidase S24/S26A/S26B HRM2_RS20165 6d74d42e5d8d8f38750be2cbcd721033 139 SUPERFAMILY SSF51306 19 137 1.64E-36 T 22-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C HRM2_RS20165 6d74d42e5d8d8f38750be2cbcd721033 139 Gene3D G3DSA:2.10.109.10 25 139 1.0E-48 T 22-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain HRM2_RS05740 94584f907dec4b30ce26d3cc354d2ca0 362 PANTHER PTHR30149:SF0 4 361 3.6E-188 T 22-04-2016 HRM2_RS05740 94584f907dec4b30ce26d3cc354d2ca0 362 Pfam PF01924 Hydrogenase formation hypA family 14 361 2.9E-150 T 22-04-2016 IPR002780 Hydrogenase formation HypD protein GO:0046872 HRM2_RS05740 94584f907dec4b30ce26d3cc354d2ca0 362 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 3 361 1.3E-143 T 22-04-2016 IPR002780 Hydrogenase formation HypD protein GO:0046872 HRM2_RS05740 94584f907dec4b30ce26d3cc354d2ca0 362 PIRSF PIRSF005622 3 362 2.2E-150 T 22-04-2016 IPR002780 Hydrogenase formation HypD protein GO:0046872 HRM2_RS05740 94584f907dec4b30ce26d3cc354d2ca0 362 PANTHER PTHR30149 4 361 3.6E-188 T 22-04-2016 HRM2_RS03435 49610aee29be794abce8d2c500884de4 905 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 40 48 - T 22-04-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 HRM2_RS03435 49610aee29be794abce8d2c500884de4 905 SMART SM01008 190 308 3.2E-40 T 22-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead HRM2_RS03435 49610aee29be794abce8d2c500884de4 905 Gene3D G3DSA:3.30.365.10 627 738 4.6E-23 T 22-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 HRM2_RS03435 49610aee29be794abce8d2c500884de4 905 SUPERFAMILY SSF54292 5 89 1.17E-17 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 HRM2_RS03435 49610aee29be794abce8d2c500884de4 905 Gene3D G3DSA:3.30.365.10 365 456 6.6E-22 T 22-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 HRM2_RS03435 49610aee29be794abce8d2c500884de4 905 Gene3D G3DSA:3.10.20.30 5 76 6.2E-20 T 22-04-2016 IPR012675 Beta-grasp domain HRM2_RS03435 49610aee29be794abce8d2c500884de4 905 SUPERFAMILY SSF54665 165 330 6.67E-42 T 22-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead HRM2_RS03435 49610aee29be794abce8d2c500884de4 905 SUPERFAMILY SSF56003 312 903 5.63E-147 T 22-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 HRM2_RS03435 49610aee29be794abce8d2c500884de4 905 Gene3D G3DSA:3.30.365.10 533 567 5.8E-48 T 22-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 HRM2_RS03435 49610aee29be794abce8d2c500884de4 905 Gene3D G3DSA:3.30.365.10 744 903 5.8E-48 T 22-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 HRM2_RS03435 49610aee29be794abce8d2c500884de4 905 SUPERFAMILY SSF47741 86 190 3.01E-35 T 22-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 HRM2_RS03435 49610aee29be794abce8d2c500884de4 905 Gene3D G3DSA:3.30.365.10 459 532 6.8E-32 T 22-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 HRM2_RS03435 49610aee29be794abce8d2c500884de4 905 Gene3D G3DSA:3.30.365.10 297 363 6.8E-32 T 22-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 HRM2_RS03435 49610aee29be794abce8d2c500884de4 905 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 325 842 6.0E-127 T 22-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 HRM2_RS03435 49610aee29be794abce8d2c500884de4 905 Gene3D G3DSA:3.90.1170.50 184 296 3.6E-35 T 22-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead HRM2_RS03435 49610aee29be794abce8d2c500884de4 905 Gene3D G3DSA:1.10.150.120 77 183 5.2E-35 T 22-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 HRM2_RS03435 49610aee29be794abce8d2c500884de4 905 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 205 308 1.1E-22 T 22-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead HRM2_RS03435 49610aee29be794abce8d2c500884de4 905 Pfam PF01799 [2Fe-2S] binding domain 75 149 4.0E-26 T 22-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 HRM2_RS03435 49610aee29be794abce8d2c500884de4 905 PANTHER PTHR11908 163 903 3.1E-139 T 22-04-2016 HRM2_RS02090 0752d0def2fb3e229ba72d4ac410bf6e 202 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 162 9.0E-5 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS02090 0752d0def2fb3e229ba72d4ac410bf6e 202 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 9.0E-5 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS02090 0752d0def2fb3e229ba72d4ac410bf6e 202 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 54 65 9.0E-5 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS02090 0752d0def2fb3e229ba72d4ac410bf6e 202 Gene3D G3DSA:3.40.50.720 1 197 9.2E-39 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS02090 0752d0def2fb3e229ba72d4ac410bf6e 202 SUPERFAMILY SSF51735 1 195 4.03E-25 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS02090 0752d0def2fb3e229ba72d4ac410bf6e 202 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 36 159 1.2E-12 T 22-04-2016 HRM2_RS02220 0b40dcb43d7f95a9ef68a4106856b9c8 424 PANTHER PTHR10668:SF77 12 238 1.5E-60 T 22-04-2016 HRM2_RS02220 0b40dcb43d7f95a9ef68a4106856b9c8 424 Pfam PF13450 NAD(P)-binding Rossmann-like domain 15 51 7.8E-8 T 22-04-2016 HRM2_RS02220 0b40dcb43d7f95a9ef68a4106856b9c8 424 Gene3D G3DSA:3.40.50.720 12 102 3.8E-24 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS02220 0b40dcb43d7f95a9ef68a4106856b9c8 424 Gene3D G3DSA:3.40.50.720 184 259 3.8E-24 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS02220 0b40dcb43d7f95a9ef68a4106856b9c8 424 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 112 123 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS02220 0b40dcb43d7f95a9ef68a4106856b9c8 424 SUPERFAMILY SSF51905 13 414 1.15E-24 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS02220 0b40dcb43d7f95a9ef68a4106856b9c8 424 Gene3D G3DSA:3.50.50.60 302 414 3.8E-6 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS02220 0b40dcb43d7f95a9ef68a4106856b9c8 424 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 352 368 3.17E-5 T 22-04-2016 HRM2_RS02220 0b40dcb43d7f95a9ef68a4106856b9c8 424 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 3.17E-5 T 22-04-2016 HRM2_RS02220 0b40dcb43d7f95a9ef68a4106856b9c8 424 PANTHER PTHR10668 12 238 1.5E-60 T 22-04-2016 HRM2_RS02220 0b40dcb43d7f95a9ef68a4106856b9c8 424 Gene3D G3DSA:3.30.70.20 103 183 1.5E-6 T 22-04-2016 HRM2_RS12450 e14b6065ebdd0c48dbf487a0289b6bb4 257 PANTHER PTHR24220 120 255 2.0E-105 T 22-04-2016 HRM2_RS12450 e14b6065ebdd0c48dbf487a0289b6bb4 257 PANTHER PTHR24220 6 104 2.0E-105 T 22-04-2016 HRM2_RS12450 e14b6065ebdd0c48dbf487a0289b6bb4 257 Gene3D G3DSA:3.40.50.300 2 251 8.2E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12450 e14b6065ebdd0c48dbf487a0289b6bb4 257 SMART SM00382 29 237 1.4E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS12450 e14b6065ebdd0c48dbf487a0289b6bb4 257 Pfam PF00005 ABC transporter 21 181 1.0E-28 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS12450 e14b6065ebdd0c48dbf487a0289b6bb4 257 SUPERFAMILY SSF52540 3 253 1.15E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12450 e14b6065ebdd0c48dbf487a0289b6bb4 257 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 230 252 4.5E-13 T 22-04-2016 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal HRM2_RS12450 e14b6065ebdd0c48dbf487a0289b6bb4 257 PANTHER PTHR24220:SF358 120 255 2.0E-105 T 22-04-2016 HRM2_RS12450 e14b6065ebdd0c48dbf487a0289b6bb4 257 PANTHER PTHR24220:SF358 6 104 2.0E-105 T 22-04-2016 HRM2_RS06985 597c1ee913d3bf27fbf96401dd048b82 246 SUPERFAMILY SSF52540 4 238 7.19E-80 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06985 597c1ee913d3bf27fbf96401dd048b82 246 PIRSF PIRSF039085 1 243 1.6E-106 T 22-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 HRM2_RS06985 597c1ee913d3bf27fbf96401dd048b82 246 PANTHER PTHR24220 6 241 7.1E-129 T 22-04-2016 HRM2_RS06985 597c1ee913d3bf27fbf96401dd048b82 246 Gene3D G3DSA:3.40.50.300 3 239 1.5E-84 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06985 597c1ee913d3bf27fbf96401dd048b82 246 PANTHER PTHR24220:SF447 6 241 7.1E-129 T 22-04-2016 HRM2_RS06985 597c1ee913d3bf27fbf96401dd048b82 246 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS06985 597c1ee913d3bf27fbf96401dd048b82 246 Pfam PF00005 ABC transporter 20 168 1.7E-37 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS06985 597c1ee913d3bf27fbf96401dd048b82 246 SMART SM00382 29 216 1.2E-18 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS10190 aa5db8f2fb898158817eaf79e526bd1b 485 SUPERFAMILY SSF47384 240 326 3.34E-18 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS10190 aa5db8f2fb898158817eaf79e526bd1b 485 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 373 483 2.1E-24 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS10190 aa5db8f2fb898158817eaf79e526bd1b 485 SMART SM00304 204 256 1.0E-4 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS10190 aa5db8f2fb898158817eaf79e526bd1b 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 463 3.2E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS10190 aa5db8f2fb898158817eaf79e526bd1b 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 469 482 3.2E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS10190 aa5db8f2fb898158817eaf79e526bd1b 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 425 3.2E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS10190 aa5db8f2fb898158817eaf79e526bd1b 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 439 3.2E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS10190 aa5db8f2fb898158817eaf79e526bd1b 485 SMART SM00387 372 485 9.4E-35 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS10190 aa5db8f2fb898158817eaf79e526bd1b 485 SUPERFAMILY SSF55874 316 483 1.02E-40 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS10190 aa5db8f2fb898158817eaf79e526bd1b 485 SUPERFAMILY SSF158472 204 254 1.1E-5 T 22-04-2016 HRM2_RS10190 aa5db8f2fb898158817eaf79e526bd1b 485 PANTHER PTHR24423 198 482 5.4E-72 T 22-04-2016 HRM2_RS10190 aa5db8f2fb898158817eaf79e526bd1b 485 PANTHER PTHR24423 5 16 5.4E-72 T 22-04-2016 HRM2_RS10190 aa5db8f2fb898158817eaf79e526bd1b 485 Gene3D G3DSA:3.30.565.10 336 483 3.8E-39 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS10190 aa5db8f2fb898158817eaf79e526bd1b 485 Pfam PF00512 His Kinase A (phospho-acceptor) domain 258 324 3.2E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS10190 aa5db8f2fb898158817eaf79e526bd1b 485 Gene3D G3DSA:1.10.287.130 247 321 5.5E-17 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS10190 aa5db8f2fb898158817eaf79e526bd1b 485 Pfam PF00672 HAMP domain 185 252 6.8E-11 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS10190 aa5db8f2fb898158817eaf79e526bd1b 485 SMART SM00388 257 325 1.2E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS00120 fcca7647cde36384686fa6540d095e60 235 SUPERFAMILY SSF52172 1 129 1.85E-38 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS00120 fcca7647cde36384686fa6540d095e60 235 Gene3D G3DSA:3.30.750.24 128 225 3.8E-6 T 22-04-2016 IPR002645 STAS domain HRM2_RS00120 fcca7647cde36384686fa6540d095e60 235 PANTHER PTHR26402 1 118 6.6E-39 T 22-04-2016 HRM2_RS00120 fcca7647cde36384686fa6540d095e60 235 Pfam PF00072 Response regulator receiver domain 3 112 8.7E-30 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS00120 fcca7647cde36384686fa6540d095e60 235 SMART SM00448 1 112 7.1E-36 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS00120 fcca7647cde36384686fa6540d095e60 235 Gene3D G3DSA:3.40.50.2300 1 119 3.2E-37 T 22-04-2016 HRM2_RS00120 fcca7647cde36384686fa6540d095e60 235 SUPERFAMILY SSF52091 130 224 7.06E-6 T 22-04-2016 IPR002645 STAS domain HRM2_RS17025 dfda5d1a42473188be7f7d9ef8db0a54 260 PRINTS PR00996 Glutamate methyltransferase family signature 100 120 1.9E-36 T 22-04-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HRM2_RS17025 dfda5d1a42473188be7f7d9ef8db0a54 260 PRINTS PR00996 Glutamate methyltransferase family signature 219 242 1.9E-36 T 22-04-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HRM2_RS17025 dfda5d1a42473188be7f7d9ef8db0a54 260 PRINTS PR00996 Glutamate methyltransferase family signature 68 80 1.9E-36 T 22-04-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HRM2_RS17025 dfda5d1a42473188be7f7d9ef8db0a54 260 PRINTS PR00996 Glutamate methyltransferase family signature 130 146 1.9E-36 T 22-04-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HRM2_RS17025 dfda5d1a42473188be7f7d9ef8db0a54 260 PRINTS PR00996 Glutamate methyltransferase family signature 200 214 1.9E-36 T 22-04-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HRM2_RS17025 dfda5d1a42473188be7f7d9ef8db0a54 260 PRINTS PR00996 Glutamate methyltransferase family signature 31 44 1.9E-36 T 22-04-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HRM2_RS17025 dfda5d1a42473188be7f7d9ef8db0a54 260 PIRSF PIRSF000410 1 260 4.2E-79 T 22-04-2016 IPR026024 Chemotaxis protein methyltransferase CheR HRM2_RS17025 dfda5d1a42473188be7f7d9ef8db0a54 260 Pfam PF03705 CheR methyltransferase, all-alpha domain 14 62 3.1E-12 T 22-04-2016 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal HRM2_RS17025 dfda5d1a42473188be7f7d9ef8db0a54 260 SUPERFAMILY SSF53335 75 255 4.43E-44 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS17025 dfda5d1a42473188be7f7d9ef8db0a54 260 Gene3D G3DSA:3.40.50.150 74 257 1.1E-55 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS17025 dfda5d1a42473188be7f7d9ef8db0a54 260 PANTHER PTHR24422:SF13 1 256 1.2E-64 T 22-04-2016 HRM2_RS17025 dfda5d1a42473188be7f7d9ef8db0a54 260 SUPERFAMILY SSF47757 3 74 4.97E-14 T 22-04-2016 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal HRM2_RS17025 dfda5d1a42473188be7f7d9ef8db0a54 260 Pfam PF01739 CheR methyltransferase, SAM binding domain 75 249 9.1E-49 T 22-04-2016 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal HRM2_RS17025 dfda5d1a42473188be7f7d9ef8db0a54 260 Gene3D G3DSA:1.10.155.10 2 71 7.3E-18 T 22-04-2016 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal HRM2_RS17025 dfda5d1a42473188be7f7d9ef8db0a54 260 SMART SM00138 9 260 1.7E-77 T 22-04-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HRM2_RS17025 dfda5d1a42473188be7f7d9ef8db0a54 260 PANTHER PTHR24422 1 256 1.2E-64 T 22-04-2016 HRM2_RS22505 333834501672dbcda3d7f93802c510f1 112 PIRSF PIRSF039144 1 112 3.6E-54 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HRM2_RS22505 333834501672dbcda3d7f93802c510f1 112 PANTHER PTHR30115 1 112 2.2E-61 T 22-04-2016 HRM2_RS22505 333834501672dbcda3d7f93802c510f1 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 6.1E-43 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HRM2_RS22505 333834501672dbcda3d7f93802c510f1 112 SUPERFAMILY SSF54913 1 112 1.33E-44 T 22-04-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta HRM2_RS22505 333834501672dbcda3d7f93802c510f1 112 Gene3D G3DSA:3.30.70.120 1 112 4.4E-50 T 22-04-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal HRM2_RS22505 333834501672dbcda3d7f93802c510f1 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 22-04-2016 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 HRM2_RS22505 333834501672dbcda3d7f93802c510f1 112 SMART SM00938 4 105 6.0E-62 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HRM2_RS22505 333834501672dbcda3d7f93802c510f1 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 22-04-2016 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 HRM2_RS22505 333834501672dbcda3d7f93802c510f1 112 PRINTS PR00340 P-II protein signature 23 41 2.5E-41 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HRM2_RS22505 333834501672dbcda3d7f93802c510f1 112 PRINTS PR00340 P-II protein signature 83 103 2.5E-41 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HRM2_RS22505 333834501672dbcda3d7f93802c510f1 112 PRINTS PR00340 P-II protein signature 52 75 2.5E-41 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HRM2_RS22505 333834501672dbcda3d7f93802c510f1 112 PRINTS PR00340 P-II protein signature 2 17 2.5E-41 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HRM2_RS22540 c4adabdfda134d0a7528e53d8cd9cf27 316 PANTHER PTHR11228 5 231 1.6E-44 T 22-04-2016 HRM2_RS22540 c4adabdfda134d0a7528e53d8cd9cf27 316 Pfam PF13394 4Fe-4S single cluster domain 26 114 3.4E-5 T 22-04-2016 HRM2_RS22540 c4adabdfda134d0a7528e53d8cd9cf27 316 Pfam PF04055 Radical SAM superfamily 24 187 1.8E-13 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS22540 c4adabdfda134d0a7528e53d8cd9cf27 316 SUPERFAMILY SSF46785 257 311 6.39E-8 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS22540 c4adabdfda134d0a7528e53d8cd9cf27 316 Gene3D G3DSA:3.20.20.70 21 234 2.0E-22 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS22540 c4adabdfda134d0a7528e53d8cd9cf27 316 Gene3D G3DSA:1.10.10.10 257 312 1.1E-7 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS22540 c4adabdfda134d0a7528e53d8cd9cf27 316 PANTHER PTHR11228:SF25 5 231 1.6E-44 T 22-04-2016 HRM2_RS22540 c4adabdfda134d0a7528e53d8cd9cf27 316 SUPERFAMILY SSF102114 25 227 2.62E-24 T 22-04-2016 HRM2_RS02825 e7aeee149df488c12b39c1643c6c96f5 251 Pfam PF00005 ABC transporter 25 174 7.9E-32 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS02825 e7aeee149df488c12b39c1643c6c96f5 251 SUPERFAMILY SSF52540 6 226 3.77E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02825 e7aeee149df488c12b39c1643c6c96f5 251 PANTHER PTHR24220:SF578 7 227 5.3E-118 T 22-04-2016 HRM2_RS02825 e7aeee149df488c12b39c1643c6c96f5 251 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS02825 e7aeee149df488c12b39c1643c6c96f5 251 SMART SM00382 34 222 1.7E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS02825 e7aeee149df488c12b39c1643c6c96f5 251 Gene3D G3DSA:3.40.50.300 6 226 1.5E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02825 e7aeee149df488c12b39c1643c6c96f5 251 PANTHER PTHR24220 7 227 5.3E-118 T 22-04-2016 HRM2_RS04685 af8ebb9f09c452fc1f81ee3c35b2e4b4 619 PANTHER PTHR10342:SF235 226 545 4.5E-77 T 22-04-2016 HRM2_RS04685 af8ebb9f09c452fc1f81ee3c35b2e4b4 619 PIRSF PIRSF004950 7 619 1.7E-138 T 22-04-2016 IPR012159 Inner membrane protein YejM HRM2_RS04685 af8ebb9f09c452fc1f81ee3c35b2e4b4 619 Pfam PF11893 Domain of unknown function (DUF3413) 16 245 6.8E-28 T 22-04-2016 IPR024588 Inner membrane protein YejM, N-terminal HRM2_RS04685 af8ebb9f09c452fc1f81ee3c35b2e4b4 619 Gene3D G3DSA:3.40.720.10 254 545 1.0E-47 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 HRM2_RS04685 af8ebb9f09c452fc1f81ee3c35b2e4b4 619 PANTHER PTHR10342 226 545 4.5E-77 T 22-04-2016 HRM2_RS04685 af8ebb9f09c452fc1f81ee3c35b2e4b4 619 Pfam PF00884 Sulfatase 254 531 1.2E-33 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 HRM2_RS04685 af8ebb9f09c452fc1f81ee3c35b2e4b4 619 SUPERFAMILY SSF53649 252 576 3.05E-63 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 HRM2_RS15710 7a030f94c694fd8a6e1ab592b55abb1a 517 Pfam PF01039 Carboxyl transferase domain 30 515 8.7E-190 T 22-04-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 HRM2_RS15710 7a030f94c694fd8a6e1ab592b55abb1a 517 SUPERFAMILY SSF52096 256 517 6.93E-83 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS15710 7a030f94c694fd8a6e1ab592b55abb1a 517 Gene3D G3DSA:3.90.226.10 5 256 1.1E-79 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS15710 7a030f94c694fd8a6e1ab592b55abb1a 517 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 166 183 5.5E-6 T 22-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 HRM2_RS15710 7a030f94c694fd8a6e1ab592b55abb1a 517 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 195 206 5.5E-6 T 22-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 HRM2_RS15710 7a030f94c694fd8a6e1ab592b55abb1a 517 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 96 110 5.5E-6 T 22-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 HRM2_RS15710 7a030f94c694fd8a6e1ab592b55abb1a 517 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 130 148 5.5E-6 T 22-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 HRM2_RS15710 7a030f94c694fd8a6e1ab592b55abb1a 517 PANTHER PTHR22855:SF14 4 517 0.0 T 22-04-2016 HRM2_RS15710 7a030f94c694fd8a6e1ab592b55abb1a 517 Gene3D G3DSA:3.90.226.10 257 516 5.9E-93 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS15710 7a030f94c694fd8a6e1ab592b55abb1a 517 PANTHER PTHR22855 4 517 0.0 T 22-04-2016 HRM2_RS15710 7a030f94c694fd8a6e1ab592b55abb1a 517 SUPERFAMILY SSF52096 6 257 9.09E-77 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS11880 399e1b6c8488a0c78b751a70dee8dc37 434 Pfam PF14535 AMP-binding enzyme C-terminal domain 336 432 1.5E-32 T 22-04-2016 IPR028154 AMP-dependent ligase, C-terminal HRM2_RS11880 399e1b6c8488a0c78b751a70dee8dc37 434 Pfam PF00501 AMP-binding enzyme 25 287 2.1E-12 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS11880 399e1b6c8488a0c78b751a70dee8dc37 434 Gene3D G3DSA:3.40.50.980 85 242 1.7E-12 T 22-04-2016 HRM2_RS11880 399e1b6c8488a0c78b751a70dee8dc37 434 PANTHER PTHR24095 57 434 3.7E-147 T 22-04-2016 HRM2_RS11880 399e1b6c8488a0c78b751a70dee8dc37 434 PIRSF PIRSF006444 1 434 1.3E-211 T 22-04-2016 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716|UniPathway: UPA00930 HRM2_RS11880 399e1b6c8488a0c78b751a70dee8dc37 434 SUPERFAMILY SSF56801 21 382 6.02E-62 T 22-04-2016 HRM2_RS11880 399e1b6c8488a0c78b751a70dee8dc37 434 Gene3D G3DSA:3.30.300.30 326 433 5.5E-39 T 22-04-2016 HRM2_RS11880 399e1b6c8488a0c78b751a70dee8dc37 434 PANTHER PTHR24095:SF175 57 434 3.7E-147 T 22-04-2016 HRM2_RS20590 42e482287ea4d1af79864cb6d63db4c0 338 PANTHER PTHR30472 1 338 1.2E-97 T 22-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 HRM2_RS20590 42e482287ea4d1af79864cb6d63db4c0 338 Gene3D G3DSA:1.10.3470.10 14 337 1.8E-97 T 22-04-2016 IPR029022 ABC transporter, BtuC-like HRM2_RS20590 42e482287ea4d1af79864cb6d63db4c0 338 SUPERFAMILY SSF81345 10 335 2.88E-76 T 22-04-2016 IPR029022 ABC transporter, BtuC-like HRM2_RS20590 42e482287ea4d1af79864cb6d63db4c0 338 Pfam PF01032 FecCD transport family 25 335 2.7E-86 T 22-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 HRM2_RS20590 42e482287ea4d1af79864cb6d63db4c0 338 PANTHER PTHR30472:SF3 1 338 1.2E-97 T 22-04-2016 HRM2_RS25375 fbabe0e974b118c4d6c52654c98ea7b7 275 PANTHER PTHR21089:SF1 1 275 1.1E-43 T 22-04-2016 HRM2_RS25375 fbabe0e974b118c4d6c52654c98ea7b7 275 SUPERFAMILY SSF51735 104 268 1.89E-18 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS25375 fbabe0e974b118c4d6c52654c98ea7b7 275 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 14 89 3.1E-19 T 22-04-2016 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS25375 fbabe0e974b118c4d6c52654c98ea7b7 275 Gene3D G3DSA:3.40.50.720 107 269 5.1E-25 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS25375 fbabe0e974b118c4d6c52654c98ea7b7 275 PANTHER PTHR21089 1 275 1.1E-43 T 22-04-2016 HRM2_RS25375 fbabe0e974b118c4d6c52654c98ea7b7 275 SUPERFAMILY SSF53223 14 101 3.74E-21 T 22-04-2016 HRM2_RS25375 fbabe0e974b118c4d6c52654c98ea7b7 275 Gene3D G3DSA:3.40.192.10 14 106 3.7E-26 T 22-04-2016 HRM2_RS00345 3026233870e7ebef70fffadf7d6ac61f 473 PANTHER PTHR24362:SF160 186 473 5.6E-59 T 22-04-2016 HRM2_RS00345 3026233870e7ebef70fffadf7d6ac61f 473 Gene3D G3DSA:2.60.120.10 96 207 1.4E-15 T 22-04-2016 IPR014710 RmlC-like jelly roll fold HRM2_RS00345 3026233870e7ebef70fffadf7d6ac61f 473 SUPERFAMILY SSF56112 209 472 1.09E-64 T 22-04-2016 IPR011009 Protein kinase-like domain HRM2_RS00345 3026233870e7ebef70fffadf7d6ac61f 473 Gene3D G3DSA:1.10.510.10 285 469 7.3E-44 T 22-04-2016 HRM2_RS00345 3026233870e7ebef70fffadf7d6ac61f 473 SUPERFAMILY SSF51206 97 205 2.88E-18 T 22-04-2016 IPR018490 Cyclic nucleotide-binding-like HRM2_RS00345 3026233870e7ebef70fffadf7d6ac61f 473 PANTHER PTHR24362 186 473 5.6E-59 T 22-04-2016 HRM2_RS00345 3026233870e7ebef70fffadf7d6ac61f 473 Pfam PF00069 Protein kinase domain 222 467 1.8E-50 T 22-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 HRM2_RS00345 3026233870e7ebef70fffadf7d6ac61f 473 Pfam PF00027 Cyclic nucleotide-binding domain 106 186 4.5E-12 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain HRM2_RS00345 3026233870e7ebef70fffadf7d6ac61f 473 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 225 248 - T 22-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 HRM2_RS00345 3026233870e7ebef70fffadf7d6ac61f 473 Gene3D G3DSA:3.30.200.20 213 284 5.5E-20 T 22-04-2016 HRM2_RS07565 0f1d74d8df9627a81f3b45b003a2406e 161 PANTHER PTHR31964:SF45 1 160 6.9E-28 T 22-04-2016 HRM2_RS07565 0f1d74d8df9627a81f3b45b003a2406e 161 SUPERFAMILY SSF52402 4 157 5.72E-34 T 22-04-2016 HRM2_RS07565 0f1d74d8df9627a81f3b45b003a2406e 161 Pfam PF00582 Universal stress protein family 4 155 1.3E-28 T 22-04-2016 IPR006016 UspA GO:0006950 HRM2_RS07565 0f1d74d8df9627a81f3b45b003a2406e 161 Gene3D G3DSA:3.40.50.620 1 157 5.6E-37 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS07565 0f1d74d8df9627a81f3b45b003a2406e 161 PRINTS PR01438 Universal stress protein signature 115 127 2.0E-12 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS07565 0f1d74d8df9627a81f3b45b003a2406e 161 PRINTS PR01438 Universal stress protein signature 133 155 2.0E-12 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS07565 0f1d74d8df9627a81f3b45b003a2406e 161 PRINTS PR01438 Universal stress protein signature 4 22 2.0E-12 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS07565 0f1d74d8df9627a81f3b45b003a2406e 161 PANTHER PTHR31964 1 160 6.9E-28 T 22-04-2016 HRM2_RS02840 eed5c5c9db622c94caf2ee984401962f 166 Pfam PF10707 PhoP regulatory network protein YrbL 13 161 4.6E-36 T 22-04-2016 IPR019647 PhoP regulatory network protein YrbL HRM2_RS08245 8c433beaf1dea3f568b3303b32b5d5d0 595 Gene3D G3DSA:3.30.70.20 542 594 1.8E-14 T 22-04-2016 HRM2_RS08245 8c433beaf1dea3f568b3303b32b5d5d0 595 SUPERFAMILY SSF52833 5 96 5.26E-25 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS08245 8c433beaf1dea3f568b3303b32b5d5d0 595 Pfam PF10531 SLBB domain 354 402 3.3E-7 T 22-04-2016 IPR019554 Soluble ligand binding domain HRM2_RS08245 8c433beaf1dea3f568b3303b32b5d5d0 595 PANTHER PTHR11780:SF0 5 565 0.0 T 22-04-2016 HRM2_RS08245 8c433beaf1dea3f568b3303b32b5d5d0 595 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 453 464 - T 22-04-2016 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 HRM2_RS08245 8c433beaf1dea3f568b3303b32b5d5d0 595 SMART SM00928 440 485 5.1E-25 T 22-04-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 HRM2_RS08245 8c433beaf1dea3f568b3303b32b5d5d0 595 SUPERFAMILY SSF142019 110 351 2.22E-93 T 22-04-2016 HRM2_RS08245 8c433beaf1dea3f568b3303b32b5d5d0 595 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 6 81 1.3E-6 T 22-04-2016 HRM2_RS08245 8c433beaf1dea3f568b3303b32b5d5d0 595 PANTHER PTHR11780 5 565 0.0 T 22-04-2016 HRM2_RS08245 8c433beaf1dea3f568b3303b32b5d5d0 595 Pfam PF00037 4Fe-4S binding domain 543 564 4.6E-6 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS08245 8c433beaf1dea3f568b3303b32b5d5d0 595 Pfam PF00037 4Fe-4S binding domain 573 594 2.4E-7 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS08245 8c433beaf1dea3f568b3303b32b5d5d0 595 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 549 560 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS08245 8c433beaf1dea3f568b3303b32b5d5d0 595 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 579 590 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS08245 8c433beaf1dea3f568b3303b32b5d5d0 595 Gene3D G3DSA:3.40.30.10 5 99 1.6E-30 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS08245 8c433beaf1dea3f568b3303b32b5d5d0 595 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 441 525 1.5E-36 T 22-04-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 HRM2_RS08245 8c433beaf1dea3f568b3303b32b5d5d0 595 SUPERFAMILY SSF54862 542 594 7.82E-15 T 22-04-2016 HRM2_RS08245 8c433beaf1dea3f568b3303b32b5d5d0 595 SUPERFAMILY SSF140490 437 537 3.92E-41 T 22-04-2016 HRM2_RS08245 8c433beaf1dea3f568b3303b32b5d5d0 595 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 161 330 3.8E-49 T 22-04-2016 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain HRM2_RS08245 8c433beaf1dea3f568b3303b32b5d5d0 595 SUPERFAMILY SSF142984 352 434 1.83E-24 T 22-04-2016 HRM2_RS09415 69dd5dcab90d6d77d677f936cb3bdbbe 677 SUPERFAMILY SSF55874 209 379 6.94E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS09415 69dd5dcab90d6d77d677f936cb3bdbbe 677 PANTHER PTHR24423 554 677 5.4E-126 T 22-04-2016 HRM2_RS09415 69dd5dcab90d6d77d677f936cb3bdbbe 677 PANTHER PTHR24423 41 94 5.4E-126 T 22-04-2016 HRM2_RS09415 69dd5dcab90d6d77d677f936cb3bdbbe 677 PANTHER PTHR24423 134 395 5.4E-126 T 22-04-2016 HRM2_RS09415 69dd5dcab90d6d77d677f936cb3bdbbe 677 Gene3D G3DSA:3.40.50.2300 398 523 3.5E-10 T 22-04-2016 HRM2_RS09415 69dd5dcab90d6d77d677f936cb3bdbbe 677 Gene3D G3DSA:3.40.50.2300 13 134 3.0E-24 T 22-04-2016 HRM2_RS09415 69dd5dcab90d6d77d677f936cb3bdbbe 677 Pfam PF00072 Response regulator receiver domain 557 672 3.2E-27 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS09415 69dd5dcab90d6d77d677f936cb3bdbbe 677 Pfam PF00072 Response regulator receiver domain 13 122 5.9E-18 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS09415 69dd5dcab90d6d77d677f936cb3bdbbe 677 SUPERFAMILY SSF52172 13 169 1.23E-26 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS09415 69dd5dcab90d6d77d677f936cb3bdbbe 677 Gene3D G3DSA:1.10.287.130 147 206 2.6E-19 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS09415 69dd5dcab90d6d77d677f936cb3bdbbe 677 PRINTS PR00344 Bacterial sensor protein C-terminal signature 308 322 3.8E-11 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS09415 69dd5dcab90d6d77d677f936cb3bdbbe 677 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 362 3.8E-11 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS09415 69dd5dcab90d6d77d677f936cb3bdbbe 677 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 381 3.8E-11 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS09415 69dd5dcab90d6d77d677f936cb3bdbbe 677 PRINTS PR00344 Bacterial sensor protein C-terminal signature 326 336 3.8E-11 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS09415 69dd5dcab90d6d77d677f936cb3bdbbe 677 SUPERFAMILY SSF52172 399 523 3.84E-10 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS09415 69dd5dcab90d6d77d677f936cb3bdbbe 677 Gene3D G3DSA:3.40.50.2300 549 676 1.4E-39 T 22-04-2016 HRM2_RS09415 69dd5dcab90d6d77d677f936cb3bdbbe 677 SUPERFAMILY SSF52172 555 676 4.41E-37 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS09415 69dd5dcab90d6d77d677f936cb3bdbbe 677 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 268 379 1.3E-24 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS09415 69dd5dcab90d6d77d677f936cb3bdbbe 677 SMART SM00388 155 220 4.3E-22 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS09415 69dd5dcab90d6d77d677f936cb3bdbbe 677 SMART SM00448 11 122 5.6E-16 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS09415 69dd5dcab90d6d77d677f936cb3bdbbe 677 SMART SM00448 555 672 1.6E-39 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS09415 69dd5dcab90d6d77d677f936cb3bdbbe 677 Gene3D G3DSA:3.30.565.10 207 384 1.1E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS09415 69dd5dcab90d6d77d677f936cb3bdbbe 677 Pfam PF00512 His Kinase A (phospho-acceptor) domain 155 220 2.1E-18 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS09415 69dd5dcab90d6d77d677f936cb3bdbbe 677 SMART SM00387 267 384 3.7E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS06330 209c5fbaa8388cb888595a67b78a3119 405 Gene3D G3DSA:3.40.50.1440 14 214 3.5E-87 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 HRM2_RS06330 209c5fbaa8388cb888595a67b78a3119 405 SMART SM00865 207 325 4.8E-59 T 22-04-2016 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain HRM2_RS06330 209c5fbaa8388cb888595a67b78a3119 405 SUPERFAMILY SSF52490 14 208 9.81E-67 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 HRM2_RS06330 209c5fbaa8388cb888595a67b78a3119 405 Gene3D G3DSA:3.30.1330.20 215 321 1.3E-48 T 22-04-2016 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain HRM2_RS06330 209c5fbaa8388cb888595a67b78a3119 405 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 22-04-2016 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 HRM2_RS06330 209c5fbaa8388cb888595a67b78a3119 405 PRINTS PR00423 Cell division protein FtsZ signature 189 211 2.1E-49 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 HRM2_RS06330 209c5fbaa8388cb888595a67b78a3119 405 PRINTS PR00423 Cell division protein FtsZ signature 212 233 2.1E-49 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 HRM2_RS06330 209c5fbaa8388cb888595a67b78a3119 405 PRINTS PR00423 Cell division protein FtsZ signature 126 147 2.1E-49 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 HRM2_RS06330 209c5fbaa8388cb888595a67b78a3119 405 PRINTS PR00423 Cell division protein FtsZ signature 98 118 2.1E-49 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 HRM2_RS06330 209c5fbaa8388cb888595a67b78a3119 405 SUPERFAMILY SSF55307 204 319 2.06E-44 T 22-04-2016 IPR008280 Tubulin/FtsZ, C-terminal HRM2_RS06330 209c5fbaa8388cb888595a67b78a3119 405 SMART SM00864 13 205 8.9E-105 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 HRM2_RS06330 209c5fbaa8388cb888595a67b78a3119 405 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 377 37.513 T 22-04-2016 IPR000158 Cell division protein FtsZ GO:0005525 HRM2_RS06330 209c5fbaa8388cb888595a67b78a3119 405 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 6 328 1.5E-126 T 22-04-2016 IPR000158 Cell division protein FtsZ GO:0005525 HRM2_RS06330 209c5fbaa8388cb888595a67b78a3119 405 Pfam PF12327 FtsZ family, C-terminal domain 222 316 2.5E-34 T 22-04-2016 IPR024757 Cell division protein FtsZ, C-terminal HRM2_RS06330 209c5fbaa8388cb888595a67b78a3119 405 PANTHER PTHR30314:SF3 1 403 7.3E-176 T 22-04-2016 HRM2_RS06330 209c5fbaa8388cb888595a67b78a3119 405 PANTHER PTHR30314 1 403 7.3E-176 T 22-04-2016 HRM2_RS06330 209c5fbaa8388cb888595a67b78a3119 405 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 14 173 6.6E-40 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 HRM2_RS06330 209c5fbaa8388cb888595a67b78a3119 405 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 22-04-2016 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 HRM2_RS14895 775dd142fa1ac8a3fa4efef66416b07a 349 SUPERFAMILY SSF158544 127 224 6.8E-22 T 22-04-2016 HRM2_RS14895 775dd142fa1ac8a3fa4efef66416b07a 349 Pfam PF03934 Type II secretion system (T2SS), protein K 48 225 9.1E-21 T 22-04-2016 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 HRM2_RS14895 775dd142fa1ac8a3fa4efef66416b07a 349 Gene3D G3DSA:1.10.40.60 129 225 8.3E-23 T 22-04-2016 HRM2_RS14895 775dd142fa1ac8a3fa4efef66416b07a 349 Gene3D G3DSA:1.10.150.280 244 291 1.3E-5 T 22-04-2016 HRM2_RS14895 775dd142fa1ac8a3fa4efef66416b07a 349 SUPERFAMILY SSF47781 242 305 7.04E-6 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 HRM2_RS14895 775dd142fa1ac8a3fa4efef66416b07a 349 PANTHER PTHR38831 21 229 1.6E-20 T 22-04-2016 HRM2_RS14895 775dd142fa1ac8a3fa4efef66416b07a 349 PANTHER PTHR38831:SF1 21 229 1.6E-20 T 22-04-2016 HRM2_RS18125 dc8bb1cb2106dd8b19b3ed6c8e4c4d2d 490 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 167 315 4.2E-9 T 22-04-2016 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HRM2_RS18125 dc8bb1cb2106dd8b19b3ed6c8e4c4d2d 490 Gene3D G3DSA:3.40.50.2000 144 316 1.2E-16 T 22-04-2016 HRM2_RS18125 dc8bb1cb2106dd8b19b3ed6c8e4c4d2d 490 Gene3D G3DSA:3.40.630.30 337 473 4.1E-21 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS18125 dc8bb1cb2106dd8b19b3ed6c8e4c4d2d 490 Pfam PF13302 Acetyltransferase (GNAT) domain 337 469 3.6E-9 T 22-04-2016 IPR000182 GNAT domain GO:0008080 HRM2_RS18125 dc8bb1cb2106dd8b19b3ed6c8e4c4d2d 490 SUPERFAMILY SSF53756 4 332 4.57E-15 T 22-04-2016 HRM2_RS18125 dc8bb1cb2106dd8b19b3ed6c8e4c4d2d 490 TIGRFAM TIGR03590 PseG: UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase 2 273 1.1E-65 T 22-04-2016 IPR020023 UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase HRM2_RS18125 dc8bb1cb2106dd8b19b3ed6c8e4c4d2d 490 SUPERFAMILY SSF55729 337 471 1.89E-17 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS14570 1a25dcf558b336d0e5dd2ff5bd9a1611 829 Pfam PF13432 Tetratricopeptide repeat 611 673 3.2E-7 T 22-04-2016 HRM2_RS14570 1a25dcf558b336d0e5dd2ff5bd9a1611 829 Pfam PF13584 Oxygen tolerance 34 499 6.9E-107 T 22-04-2016 IPR025738 Aerotolerance-related protein BatD HRM2_RS14570 1a25dcf558b336d0e5dd2ff5bd9a1611 829 PANTHER PTHR40940:SF1 8 575 1.6E-25 T 22-04-2016 HRM2_RS14570 1a25dcf558b336d0e5dd2ff5bd9a1611 829 SUPERFAMILY SSF48452 604 679 7.05E-13 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS14570 1a25dcf558b336d0e5dd2ff5bd9a1611 829 Gene3D G3DSA:1.25.40.10 603 679 1.7E-13 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS14570 1a25dcf558b336d0e5dd2ff5bd9a1611 829 PANTHER PTHR40940 8 575 1.6E-25 T 22-04-2016 HRM2_RS14570 1a25dcf558b336d0e5dd2ff5bd9a1611 829 SMART SM00028 639 672 4.4E-4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS14570 1a25dcf558b336d0e5dd2ff5bd9a1611 829 SMART SM00028 605 638 80.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS12245 1cca272cf4f99c07b1f3a1e28d136399 473 SUPERFAMILY SSF53448 1 281 2.14E-72 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS12245 1cca272cf4f99c07b1f3a1e28d136399 473 Pfam PF00483 Nucleotidyl transferase 4 283 1.3E-69 T 22-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 HRM2_RS12245 1cca272cf4f99c07b1f3a1e28d136399 473 PANTHER PTHR12526 353 471 6.4E-100 T 22-04-2016 HRM2_RS12245 1cca272cf4f99c07b1f3a1e28d136399 473 PANTHER PTHR12526 153 290 6.4E-100 T 22-04-2016 HRM2_RS12245 1cca272cf4f99c07b1f3a1e28d136399 473 Gene3D G3DSA:2.60.120.10 359 470 1.9E-45 T 22-04-2016 IPR014710 RmlC-like jelly roll fold HRM2_RS12245 1cca272cf4f99c07b1f3a1e28d136399 473 SUPERFAMILY SSF51182 186 471 1.73E-81 T 22-04-2016 IPR011051 RmlC-like cupin domain HRM2_RS12245 1cca272cf4f99c07b1f3a1e28d136399 473 PANTHER PTHR12526:SF387 353 471 6.4E-100 T 22-04-2016 HRM2_RS12245 1cca272cf4f99c07b1f3a1e28d136399 473 PANTHER PTHR12526:SF387 153 290 6.4E-100 T 22-04-2016 HRM2_RS12245 1cca272cf4f99c07b1f3a1e28d136399 473 Gene3D G3DSA:3.90.550.10 1 272 1.7E-98 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS12245 1cca272cf4f99c07b1f3a1e28d136399 473 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 2 470 1.0E-216 T 22-04-2016 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882|UniPathway: UPA00126 HRM2_RS12245 1cca272cf4f99c07b1f3a1e28d136399 473 Pfam PF01050 Mannose-6-phosphate isomerase 316 466 7.7E-71 T 22-04-2016 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882|UniPathway: UPA00126 HRM2_RS23220 6dd809a57427ec3ef0d5b438a3c0f4e3 476 SUPERFAMILY SSF56176 13 227 1.73E-48 T 22-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 HRM2_RS23220 6dd809a57427ec3ef0d5b438a3c0f4e3 476 PANTHER PTHR11748:SF35 12 472 3.2E-75 T 22-04-2016 HRM2_RS23220 6dd809a57427ec3ef0d5b438a3c0f4e3 476 Pfam PF02913 FAD linked oxidases, C-terminal domain 231 471 1.0E-24 T 22-04-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 HRM2_RS23220 6dd809a57427ec3ef0d5b438a3c0f4e3 476 SUPERFAMILY SSF55103 230 472 4.91E-25 T 22-04-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 HRM2_RS23220 6dd809a57427ec3ef0d5b438a3c0f4e3 476 Gene3D G3DSA:3.30.465.10 108 226 5.9E-28 T 22-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 HRM2_RS23220 6dd809a57427ec3ef0d5b438a3c0f4e3 476 PANTHER PTHR11748 12 472 3.2E-75 T 22-04-2016 HRM2_RS23220 6dd809a57427ec3ef0d5b438a3c0f4e3 476 Gene3D G3DSA:1.10.45.10 442 471 3.2E-8 T 22-04-2016 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 HRM2_RS23220 6dd809a57427ec3ef0d5b438a3c0f4e3 476 Gene3D G3DSA:3.30.43.10 13 106 7.3E-20 T 22-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 HRM2_RS23220 6dd809a57427ec3ef0d5b438a3c0f4e3 476 Pfam PF01565 FAD binding domain 52 191 2.7E-36 T 22-04-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 HRM2_RS03530 692963f5692845cb1f81ba6a6017a287 99 PANTHER PTHR36924 1 97 3.0E-38 T 22-04-2016 HRM2_RS03530 692963f5692845cb1f81ba6a6017a287 99 PANTHER PTHR36924:SF1 1 97 3.0E-38 T 22-04-2016 HRM2_RS03530 692963f5692845cb1f81ba6a6017a287 99 Gene3D G3DSA:1.10.260.40 1 92 6.0E-32 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS03530 692963f5692845cb1f81ba6a6017a287 99 SMART SM00530 13 68 6.5E-6 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS03530 692963f5692845cb1f81ba6a6017a287 99 SUPERFAMILY SSF47413 8 91 8.32E-26 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS03530 692963f5692845cb1f81ba6a6017a287 99 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 5 81 1.1E-29 T 22-04-2016 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 HRM2_RS03530 692963f5692845cb1f81ba6a6017a287 99 Pfam PF01381 Helix-turn-helix 14 67 1.3E-8 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS10100 eae2f77368b02eba50e5430c11941ce9 226 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 109 1.5E-29 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HRM2_RS10100 eae2f77368b02eba50e5430c11941ce9 226 SUPERFAMILY SSF161098 13 200 3.14E-46 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS10100 eae2f77368b02eba50e5430c11941ce9 226 PANTHER PTHR30614 1 220 2.0E-81 T 22-04-2016 HRM2_RS10100 eae2f77368b02eba50e5430c11941ce9 226 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 210 2.5E-15 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS10100 eae2f77368b02eba50e5430c11941ce9 226 Gene3D G3DSA:1.10.3720.10 13 214 2.2E-46 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS00710 6bf8853df9f31948aaa72755fbc5ba33 407 SUPERFAMILY SSF51161 295 402 4.71E-17 T 22-04-2016 IPR011004 Trimeric LpxA-like HRM2_RS00710 6bf8853df9f31948aaa72755fbc5ba33 407 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 11 30 - T 22-04-2016 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 HRM2_RS00710 6bf8853df9f31948aaa72755fbc5ba33 407 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 195 205 - T 22-04-2016 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 HRM2_RS00710 6bf8853df9f31948aaa72755fbc5ba33 407 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 97 105 - T 22-04-2016 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 HRM2_RS00710 6bf8853df9f31948aaa72755fbc5ba33 407 Pfam PF00483 Nucleotidyl transferase 9 273 5.6E-66 T 22-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 HRM2_RS00710 6bf8853df9f31948aaa72755fbc5ba33 407 PANTHER PTHR22572 6 379 4.7E-160 T 22-04-2016 HRM2_RS00710 6bf8853df9f31948aaa72755fbc5ba33 407 PANTHER PTHR22572:SF10 6 379 4.7E-160 T 22-04-2016 HRM2_RS00710 6bf8853df9f31948aaa72755fbc5ba33 407 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 6 379 2.5E-147 T 22-04-2016 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 HRM2_RS00710 6bf8853df9f31948aaa72755fbc5ba33 407 SUPERFAMILY SSF53448 6 276 3.52E-77 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS00710 6bf8853df9f31948aaa72755fbc5ba33 407 SUPERFAMILY SSF53448 343 359 3.52E-77 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS00710 6bf8853df9f31948aaa72755fbc5ba33 407 Gene3D G3DSA:3.90.550.10 326 369 1.1E-80 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS00710 6bf8853df9f31948aaa72755fbc5ba33 407 Gene3D G3DSA:3.90.550.10 9 283 1.1E-80 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS00710 6bf8853df9f31948aaa72755fbc5ba33 407 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 2 405 48.434 T 22-04-2016 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 HRM2_RS13805 32601717a038f53507b26892257f07e2 152 SUPERFAMILY SSF55804 1 146 4.19E-35 T 22-04-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 HRM2_RS13805 32601717a038f53507b26892257f07e2 152 PANTHER PTHR30505 1 152 2.9E-36 T 22-04-2016 HRM2_RS13805 32601717a038f53507b26892257f07e2 152 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 8 146 6.7E-30 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HRM2_RS13805 32601717a038f53507b26892257f07e2 152 Gene3D G3DSA:3.40.930.10 1 151 7.1E-40 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HRM2_RS13805 32601717a038f53507b26892257f07e2 152 PANTHER PTHR30505:SF5 1 152 2.9E-36 T 22-04-2016 HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 SMART SM00316 143 210 1.8E-5 T 22-04-2016 IPR022967 RNA-binding domain, S1 HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 SMART SM00316 59 127 2.1E-5 T 22-04-2016 IPR022967 RNA-binding domain, S1 HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 SMART SM00316 314 386 2.5E-26 T 22-04-2016 IPR022967 RNA-binding domain, S1 HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 SMART SM00316 401 473 1.6E-22 T 22-04-2016 IPR022967 RNA-binding domain, S1 HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 SMART SM00316 488 559 1.5E-24 T 22-04-2016 IPR022967 RNA-binding domain, S1 HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 SMART SM00316 229 299 1.3E-25 T 22-04-2016 IPR022967 RNA-binding domain, S1 HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 PANTHER PTHR10724:SF6 35 553 1.7E-217 T 22-04-2016 HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 PANTHER PTHR10724 35 553 1.7E-217 T 22-04-2016 HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 SUPERFAMILY SSF50249 294 400 7.55E-28 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 SUPERFAMILY SSF50249 469 572 8.24E-26 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 55 559 1.0E-193 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 Gene3D G3DSA:2.40.50.140 133 210 1.1E-11 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 PRINTS PR00681 Ribosomal protein S1 signature 124 143 3.0E-77 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 PRINTS PR00681 Ribosomal protein S1 signature 79 93 3.0E-77 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 PRINTS PR00681 Ribosomal protein S1 signature 251 272 3.0E-77 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 PRINTS PR00681 Ribosomal protein S1 signature 61 79 3.0E-77 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 PRINTS PR00681 Ribosomal protein S1 signature 329 348 3.0E-77 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 PRINTS PR00681 Ribosomal protein S1 signature 369 387 3.0E-77 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 PRINTS PR00681 Ribosomal protein S1 signature 148 164 3.0E-77 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 PRINTS PR00681 Ribosomal protein S1 signature 165 182 3.0E-77 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 PRINTS PR00681 Ribosomal protein S1 signature 194 214 3.0E-77 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 SUPERFAMILY SSF50249 53 152 3.88E-17 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 Gene3D G3DSA:2.40.50.140 53 127 9.9E-12 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 SUPERFAMILY SSF50249 128 213 4.43E-13 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 Pfam PF00575 S1 RNA binding domain 400 473 2.0E-17 T 22-04-2016 IPR003029 S1 domain GO:0003676 HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 Pfam PF00575 S1 RNA binding domain 58 126 1.6E-9 T 22-04-2016 IPR003029 S1 domain GO:0003676 HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 Pfam PF00575 S1 RNA binding domain 229 299 4.8E-17 T 22-04-2016 IPR003029 S1 domain GO:0003676 HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 Pfam PF00575 S1 RNA binding domain 487 559 1.2E-18 T 22-04-2016 IPR003029 S1 domain GO:0003676 HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 Pfam PF00575 S1 RNA binding domain 313 386 6.9E-20 T 22-04-2016 IPR003029 S1 domain GO:0003676 HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 Pfam PF00575 S1 RNA binding domain 146 210 1.0E-6 T 22-04-2016 IPR003029 S1 domain GO:0003676 HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 Gene3D G3DSA:2.40.50.140 391 477 4.2E-28 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 Gene3D G3DSA:2.40.50.140 478 564 4.9E-28 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 SUPERFAMILY SSF50249 229 316 1.07E-25 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 Gene3D G3DSA:2.40.50.140 316 390 1.4E-28 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 SUPERFAMILY SSF50249 381 492 8.58E-28 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS12315 90fe33b798ecc0aa1a21bd874911c83e 605 Gene3D G3DSA:2.40.50.140 231 315 7.0E-28 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS25020 1f91684fada0b8c0e8383c7768dafb13 422 Pfam PF13247 4Fe-4S dicluster domain 73 155 3.3E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS25020 1f91684fada0b8c0e8383c7768dafb13 422 PANTHER PTHR30176:SF2 222 413 3.5E-23 T 22-04-2016 HRM2_RS25020 1f91684fada0b8c0e8383c7768dafb13 422 Gene3D G3DSA:3.30.70.20 323 404 4.9E-10 T 22-04-2016 HRM2_RS25020 1f91684fada0b8c0e8383c7768dafb13 422 Pfam PF12837 4Fe-4S binding domain 28 47 9.1E-7 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS25020 1f91684fada0b8c0e8383c7768dafb13 422 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 108 119 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS25020 1f91684fada0b8c0e8383c7768dafb13 422 Pfam PF12801 4Fe-4S binding domain 364 373 740.0 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS25020 1f91684fada0b8c0e8383c7768dafb13 422 Pfam PF12801 4Fe-4S binding domain 175 208 410.0 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS25020 1f91684fada0b8c0e8383c7768dafb13 422 Pfam PF12801 4Fe-4S binding domain 214 258 3.8E-12 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS25020 1f91684fada0b8c0e8383c7768dafb13 422 Pfam PF12801 4Fe-4S binding domain 272 296 210.0 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS25020 1f91684fada0b8c0e8383c7768dafb13 422 Pfam PF12801 4Fe-4S binding domain 324 348 1.1E-4 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS25020 1f91684fada0b8c0e8383c7768dafb13 422 SUPERFAMILY SSF54862 280 405 6.4E-15 T 22-04-2016 HRM2_RS25020 1f91684fada0b8c0e8383c7768dafb13 422 SUPERFAMILY SSF54862 224 246 6.4E-15 T 22-04-2016 HRM2_RS25020 1f91684fada0b8c0e8383c7768dafb13 422 Gene3D G3DSA:3.30.70.20 114 156 1.1E-10 T 22-04-2016 HRM2_RS25020 1f91684fada0b8c0e8383c7768dafb13 422 SUPERFAMILY SSF54862 26 165 3.28E-37 T 22-04-2016 HRM2_RS25020 1f91684fada0b8c0e8383c7768dafb13 422 PANTHER PTHR30176 222 413 3.5E-23 T 22-04-2016 HRM2_RS25020 1f91684fada0b8c0e8383c7768dafb13 422 Gene3D G3DSA:3.30.70.20 82 113 6.4E-12 T 22-04-2016 HRM2_RS25020 1f91684fada0b8c0e8383c7768dafb13 422 Gene3D G3DSA:3.30.70.20 28 81 1.0E-12 T 22-04-2016 HRM2_RS14415 6abbdcb8082cf35e10c482cd72d94b55 106 Pfam PF01381 Helix-turn-helix 17 65 9.8E-9 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS14415 6abbdcb8082cf35e10c482cd72d94b55 106 SUPERFAMILY SSF47413 7 65 1.21E-11 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS14415 6abbdcb8082cf35e10c482cd72d94b55 106 Gene3D G3DSA:1.10.260.40 6 69 6.1E-11 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS14415 6abbdcb8082cf35e10c482cd72d94b55 106 SMART SM00530 16 70 5.4E-7 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS14245 762ed5399f5fe1b6a1f405e4eff51c1f 316 Pfam PF00850 Histone deacetylase domain 21 313 1.3E-87 T 22-04-2016 IPR023801 Histone deacetylase domain HRM2_RS14245 762ed5399f5fe1b6a1f405e4eff51c1f 316 PANTHER PTHR10625 2 314 1.5E-107 T 22-04-2016 IPR000286 Histone deacetylase superfamily HRM2_RS14245 762ed5399f5fe1b6a1f405e4eff51c1f 316 SUPERFAMILY SSF52768 2 314 1.68E-106 T 22-04-2016 HRM2_RS14245 762ed5399f5fe1b6a1f405e4eff51c1f 316 PRINTS PR01270 Histone deacetylase superfamily signature 243 253 3.7E-17 T 22-04-2016 IPR000286 Histone deacetylase superfamily HRM2_RS14245 762ed5399f5fe1b6a1f405e4eff51c1f 316 PRINTS PR01270 Histone deacetylase superfamily signature 123 146 3.7E-17 T 22-04-2016 IPR000286 Histone deacetylase superfamily HRM2_RS14245 762ed5399f5fe1b6a1f405e4eff51c1f 316 PRINTS PR01270 Histone deacetylase superfamily signature 157 172 3.7E-17 T 22-04-2016 IPR000286 Histone deacetylase superfamily HRM2_RS14245 762ed5399f5fe1b6a1f405e4eff51c1f 316 PANTHER PTHR10625:SF104 2 314 1.5E-107 T 22-04-2016 HRM2_RS14245 762ed5399f5fe1b6a1f405e4eff51c1f 316 Gene3D G3DSA:3.40.800.20 2 315 6.0E-104 T 22-04-2016 IPR023801 Histone deacetylase domain HRM2_RS08470 5077b1d81d70678526dd4564fff86288 433 PIRSF PIRSF001563 1 431 1.7E-141 T 22-04-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 HRM2_RS08470 5077b1d81d70678526dd4564fff86288 433 SUPERFAMILY SSF53623 3 294 9.73E-88 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HRM2_RS08470 5077b1d81d70678526dd4564fff86288 433 Pfam PF08245 Mur ligase middle domain 47 266 6.8E-17 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HRM2_RS08470 5077b1d81d70678526dd4564fff86288 433 SUPERFAMILY SSF53244 294 426 1.37E-27 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HRM2_RS08470 5077b1d81d70678526dd4564fff86288 433 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 45 68 - T 22-04-2016 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 HRM2_RS08470 5077b1d81d70678526dd4564fff86288 433 PANTHER PTHR11136 2 425 2.7E-130 T 22-04-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 HRM2_RS08470 5077b1d81d70678526dd4564fff86288 433 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 138 153 - T 22-04-2016 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 HRM2_RS08470 5077b1d81d70678526dd4564fff86288 433 Gene3D G3DSA:3.90.190.20 296 427 8.1E-35 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HRM2_RS08470 5077b1d81d70678526dd4564fff86288 433 Gene3D G3DSA:3.40.1190.10 3 295 1.0E-94 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HRM2_RS08470 5077b1d81d70678526dd4564fff86288 433 Pfam PF02875 Mur ligase family, glutamate ligase domain 294 366 2.0E-7 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HRM2_RS08470 5077b1d81d70678526dd4564fff86288 433 TIGRFAM TIGR01499 folC: bifunctional protein FolC 25 425 7.3E-119 T 22-04-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 HRM2_RS08470 5077b1d81d70678526dd4564fff86288 433 PANTHER PTHR11136:SF0 2 425 2.7E-130 T 22-04-2016 HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 SUPERFAMILY SSF52172 754 877 9.68E-29 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 Pfam PF00072 Response regulator receiver domain 757 868 3.4E-20 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 Pfam PF08269 Cache domain 33 195 1.4E-42 T 22-04-2016 IPR004010 Double Cache domain 2 HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 Gene3D G3DSA:3.30.450.20 27 186 4.7E-47 T 22-04-2016 HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 Gene3D G3DSA:3.30.565.10 557 736 5.3E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 SUPERFAMILY SSF55785 228 359 4.51E-22 T 22-04-2016 IPR000014 PAS domain HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 Pfam PF00512 His Kinase A (phospho-acceptor) domain 504 567 9.9E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 PRINTS PR00344 Bacterial sensor protein C-terminal signature 664 678 5.6E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 PRINTS PR00344 Bacterial sensor protein C-terminal signature 682 692 5.6E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 PRINTS PR00344 Bacterial sensor protein C-terminal signature 695 713 5.6E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 PRINTS PR00344 Bacterial sensor protein C-terminal signature 719 732 5.6E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 SUPERFAMILY SSF55874 561 733 1.31E-34 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 SMART SM00388 504 570 8.9E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 Pfam PF08447 PAS fold 263 354 3.3E-10 T 22-04-2016 IPR013655 PAS fold-3 GO:0005515 HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 234 368 2.4E-21 T 22-04-2016 IPR000014 PAS domain HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 PANTHER PTHR24423:SF544 1 876 5.6E-139 T 22-04-2016 HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 SMART SM00086 447 489 44.0 T 22-04-2016 IPR001610 PAC motif HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 SMART SM00086 319 361 1.7E-9 T 22-04-2016 IPR001610 PAC motif HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 SMART SM00091 373 437 140.0 T 22-04-2016 IPR000014 PAS domain HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 SMART SM00091 238 305 3.4E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 SMART SM00448 755 868 3.2E-23 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 Gene3D G3DSA:3.30.450.20 365 487 5.8E-13 T 22-04-2016 HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 Gene3D G3DSA:3.30.450.20 228 359 6.1E-25 T 22-04-2016 HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 Gene3D G3DSA:3.40.50.2300 755 877 2.9E-28 T 22-04-2016 HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 612 733 2.0E-19 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 SMART SM00387 611 735 2.8E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 SMART SM01049 37 133 5.1E-31 T 22-04-2016 IPR033480 Single Cache domain 2 HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 Gene3D G3DSA:1.10.287.130 498 556 3.4E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 SUPERFAMILY SSF47384 495 566 3.14E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 SUPERFAMILY SSF55785 358 487 3.32E-12 T 22-04-2016 IPR000014 PAS domain HRM2_RS24950 361e43e68da35b55da199a43410786c4 879 PANTHER PTHR24423 1 876 5.6E-139 T 22-04-2016 HRM2_RS14975 9f0d6591f947f36c897ae451a7a7633a 261 TIGRFAM TIGR00294 TIGR00294: GTP cyclohydrolase 102 251 2.0E-29 T 22-04-2016 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 HRM2_RS14975 9f0d6591f947f36c897ae451a7a7633a 261 Hamap MF_01527_B GTP cyclohydrolase FolE2 [folE2]. 1 256 37.216 T 22-04-2016 IPR022838 GTP cyclohydrolase FolE2 GO:0003934|GO:0035998 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 HRM2_RS14975 9f0d6591f947f36c897ae451a7a7633a 261 Gene3D G3DSA:3.10.270.10 1 255 6.5E-105 T 22-04-2016 HRM2_RS14975 9f0d6591f947f36c897ae451a7a7633a 261 PANTHER PTHR36445:SF1 1 255 9.7E-81 T 22-04-2016 HRM2_RS14975 9f0d6591f947f36c897ae451a7a7633a 261 Pfam PF02649 Type I GTP cyclohydrolase folE2 1 251 2.8E-96 T 22-04-2016 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 HRM2_RS14975 9f0d6591f947f36c897ae451a7a7633a 261 PANTHER PTHR36445 1 255 9.7E-81 T 22-04-2016 HRM2_RS11135 3504fcf311c48f1b304847713bdccfd5 409 SUPERFAMILY SSF56176 330 406 5.45E-20 T 22-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 HRM2_RS11135 3504fcf311c48f1b304847713bdccfd5 409 Gene3D G3DSA:3.10.580.10 180 311 1.6E-22 T 22-04-2016 HRM2_RS11135 3504fcf311c48f1b304847713bdccfd5 409 Pfam PF00571 CBS domain 263 317 3.6E-6 T 22-04-2016 IPR000644 CBS domain HRM2_RS11135 3504fcf311c48f1b304847713bdccfd5 409 Pfam PF00571 CBS domain 195 246 0.0064 T 22-04-2016 IPR000644 CBS domain HRM2_RS11135 3504fcf311c48f1b304847713bdccfd5 409 Pfam PF03471 Transporter associated domain 333 407 1.6E-21 T 22-04-2016 IPR005170 Transporter-associated domain HRM2_RS11135 3504fcf311c48f1b304847713bdccfd5 409 SMART SM01091 332 409 7.7E-22 T 22-04-2016 IPR005170 Transporter-associated domain HRM2_RS11135 3504fcf311c48f1b304847713bdccfd5 409 Gene3D G3DSA:3.30.465.10 312 405 6.3E-25 T 22-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 HRM2_RS11135 3504fcf311c48f1b304847713bdccfd5 409 SUPERFAMILY SSF54631 182 320 1.71E-31 T 22-04-2016 HRM2_RS11135 3504fcf311c48f1b304847713bdccfd5 409 Pfam PF01595 Domain of unknown function DUF21 7 179 4.2E-50 T 22-04-2016 IPR002550 Domain of unknown function DUF21 HRM2_RS11135 3504fcf311c48f1b304847713bdccfd5 409 PANTHER PTHR22777 1 403 4.3E-150 T 22-04-2016 HRM2_RS02290 a1cf6ea325449eb5a14c8182414b3f28 155 PANTHER PTHR33867 7 155 1.0E-32 T 22-04-2016 HRM2_RS02290 a1cf6ea325449eb5a14c8182414b3f28 155 SUPERFAMILY SSF74942 91 154 3.27E-14 T 22-04-2016 IPR028998 Ribosome maturation factor RimP, C-terminal HRM2_RS02290 a1cf6ea325449eb5a14c8182414b3f28 155 Gene3D G3DSA:3.30.300.70 11 87 2.7E-21 T 22-04-2016 IPR028989 Ribosome maturation factor RimP, N-terminal HRM2_RS02290 a1cf6ea325449eb5a14c8182414b3f28 155 Gene3D G3DSA:2.30.30.180 94 155 9.7E-12 T 22-04-2016 IPR028998 Ribosome maturation factor RimP, C-terminal HRM2_RS02290 a1cf6ea325449eb5a14c8182414b3f28 155 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 13 148 19.764 T 22-04-2016 IPR003728 Ribosome maturation factor RimP GO:0042274 HRM2_RS02290 a1cf6ea325449eb5a14c8182414b3f28 155 SUPERFAMILY SSF75420 8 89 9.55E-20 T 22-04-2016 IPR028989 Ribosome maturation factor RimP, N-terminal HRM2_RS02290 a1cf6ea325449eb5a14c8182414b3f28 155 PANTHER PTHR33867:SF1 7 155 1.0E-32 T 22-04-2016 HRM2_RS02290 a1cf6ea325449eb5a14c8182414b3f28 155 Pfam PF02576 Putative ribosome maturation factor RimP 19 154 4.1E-35 T 22-04-2016 IPR003728 Ribosome maturation factor RimP GO:0042274 HRM2_RS08725 e96d81b4ef5e2ce23bb103734569d2b3 261 Gene3D G3DSA:2.30.30.330 33 232 3.0E-21 T 22-04-2016 HRM2_RS08725 e96d81b4ef5e2ce23bb103734569d2b3 261 SUPERFAMILY SSF54001 33 139 1.67E-25 T 22-04-2016 HRM2_RS08725 e96d81b4ef5e2ce23bb103734569d2b3 261 SUPERFAMILY SSF54001 166 234 1.67E-25 T 22-04-2016 HRM2_RS08725 e96d81b4ef5e2ce23bb103734569d2b3 261 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 34 136 5.0E-12 T 22-04-2016 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family HRM2_RS14720 5786266126e5ffd8885b1ce0081f811f 308 SUPERFAMILY SSF53448 1 244 6.06E-46 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS14720 5786266126e5ffd8885b1ce0081f811f 308 Pfam PF00535 Glycosyl transferase family 2 7 133 1.6E-20 T 22-04-2016 IPR001173 Glycosyltransferase 2-like HRM2_RS14720 5786266126e5ffd8885b1ce0081f811f 308 PANTHER PTHR22916 1 227 7.8E-35 T 22-04-2016 HRM2_RS14720 5786266126e5ffd8885b1ce0081f811f 308 Gene3D G3DSA:3.90.550.10 4 222 2.3E-35 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS14720 5786266126e5ffd8885b1ce0081f811f 308 PANTHER PTHR22916:SF9 1 227 7.8E-35 T 22-04-2016 HRM2_RS20855 f1b816aa8491a79046ed5e6dcade22ff 537 SMART SM00487 115 322 5.8E-50 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS20855 f1b816aa8491a79046ed5e6dcade22ff 537 Gene3D G3DSA:3.40.50.300 91 312 1.1E-70 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20855 f1b816aa8491a79046ed5e6dcade22ff 537 PANTHER PTHR24031 96 537 1.9E-148 T 22-04-2016 HRM2_RS20855 f1b816aa8491a79046ed5e6dcade22ff 537 Gene3D G3DSA:3.40.50.300 313 468 2.5E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20855 f1b816aa8491a79046ed5e6dcade22ff 537 Pfam PF00271 Helicase conserved C-terminal domain 331 439 5.5E-30 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS20855 f1b816aa8491a79046ed5e6dcade22ff 537 Hamap MF_00661 ATP-dependent RNA helicase RhlB [rhlB]. 95 477 51.84 T 22-04-2016 IPR023554 ATP-dependent RNA helicase RhlB type GO:0004004 HRM2_RS20855 f1b816aa8491a79046ed5e6dcade22ff 537 SUPERFAMILY SSF52540 172 452 2.7E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20855 f1b816aa8491a79046ed5e6dcade22ff 537 SMART SM00490 358 439 1.7E-33 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS20855 f1b816aa8491a79046ed5e6dcade22ff 537 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 251 259 - T 22-04-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site HRM2_RS20855 f1b816aa8491a79046ed5e6dcade22ff 537 Pfam PF00270 DEAD/DEAH box helicase 121 291 2.0E-45 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HRM2_RS20855 f1b816aa8491a79046ed5e6dcade22ff 537 PANTHER PTHR24031:SF261 96 537 1.9E-148 T 22-04-2016 HRM2_RS18325 6c15c9cf7604bac251a45c7972f4e212 262 PANTHER PTHR30065 1 262 6.8E-60 T 22-04-2016 HRM2_RS18325 6c15c9cf7604bac251a45c7972f4e212 262 PANTHER PTHR30065:SF1 1 262 6.8E-60 T 22-04-2016 HRM2_RS18325 6c15c9cf7604bac251a45c7972f4e212 262 Pfam PF01311 Bacterial export proteins, family 1 14 244 1.3E-63 T 22-04-2016 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 HRM2_RS18325 6c15c9cf7604bac251a45c7972f4e212 262 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 14 254 1.2E-57 T 22-04-2016 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 HRM2_RS18325 6c15c9cf7604bac251a45c7972f4e212 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 81 100 1.8E-24 T 22-04-2016 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 HRM2_RS18325 6c15c9cf7604bac251a45c7972f4e212 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 203 222 1.8E-24 T 22-04-2016 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 HRM2_RS18325 6c15c9cf7604bac251a45c7972f4e212 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 181 203 1.8E-24 T 22-04-2016 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 HRM2_RS18325 6c15c9cf7604bac251a45c7972f4e212 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 21 42 1.8E-24 T 22-04-2016 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 SUPERFAMILY SSF47384 653 726 2.94E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 PANTHER PTHR24423:SF458 87 1031 7.7E-159 T 22-04-2016 HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 Gene3D G3DSA:3.30.450.20 522 645 2.2E-9 T 22-04-2016 HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 Pfam PF00072 Response regulator receiver domain 915 1026 2.2E-18 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 Pfam PF13426 PAS domain 548 647 0.0013 T 22-04-2016 IPR000014 PAS domain HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 SMART SM00388 663 729 1.7E-4 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 Gene3D G3DSA:3.30.450.20 154 325 3.3E-8 T 22-04-2016 HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 SMART SM00086 482 524 0.002 T 22-04-2016 IPR001610 PAC motif HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 SUPERFAMILY SSF55785 412 526 3.84E-22 T 22-04-2016 IPR000014 PAS domain HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 Pfam PF00512 His Kinase A (phospho-acceptor) domain 664 727 1.3E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 SUPERFAMILY SSF55785 521 646 3.14E-9 T 22-04-2016 IPR000014 PAS domain HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 Gene3D G3DSA:3.30.565.10 704 894 1.7E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 SUPERFAMILY SSF52172 915 1031 2.99E-25 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 PRINTS PR00344 Bacterial sensor protein C-terminal signature 853 871 3.8E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 PRINTS PR00344 Bacterial sensor protein C-terminal signature 822 836 3.8E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 PRINTS PR00344 Bacterial sensor protein C-terminal signature 840 850 3.8E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 PRINTS PR00344 Bacterial sensor protein C-terminal signature 877 890 3.8E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 Pfam PF08447 PAS fold 432 516 2.0E-14 T 22-04-2016 IPR013655 PAS fold-3 GO:0005515 HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 SMART SM00448 913 1026 6.4E-20 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 Pfam PF02743 Cache domain 40 272 2.1E-12 T 22-04-2016 IPR033479 Double Cache domain 1 HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 SMART SM00387 770 893 1.5E-23 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 771 891 1.6E-17 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 Gene3D G3DSA:3.40.50.2300 913 1032 6.1E-28 T 22-04-2016 HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 404 531 8.3E-15 T 22-04-2016 IPR000014 PAS domain HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 SMART SM00091 536 600 6.2 T 22-04-2016 IPR000014 PAS domain HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 SMART SM00091 407 476 4.8E-7 T 22-04-2016 IPR000014 PAS domain HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 Pfam PF00672 HAMP domain 329 397 6.1E-17 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 SUPERFAMILY SSF55874 719 895 1.83E-37 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 SMART SM00304 348 400 1.2E-15 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 PANTHER PTHR24423 87 1031 7.7E-159 T 22-04-2016 HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 SUPERFAMILY SSF158472 350 399 3.66E-13 T 22-04-2016 HRM2_RS25530 ec4a9637b2ca1e83e6592991e53ea6fe 1034 Gene3D G3DSA:3.30.450.20 402 521 1.8E-23 T 22-04-2016 HRM2_RS00980 ebb1ae0ba202b22ed14ec962b2d9535a 415 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 264 284 - T 22-04-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 HRM2_RS00980 ebb1ae0ba202b22ed14ec962b2d9535a 415 Pfam PF00465 Iron-containing alcohol dehydrogenase 14 393 9.3E-103 T 22-04-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 HRM2_RS00980 ebb1ae0ba202b22ed14ec962b2d9535a 415 PANTHER PTHR11496:SF75 21 407 2.2E-88 T 22-04-2016 HRM2_RS00980 ebb1ae0ba202b22ed14ec962b2d9535a 415 SUPERFAMILY SSF56796 6 406 1.1E-102 T 22-04-2016 HRM2_RS00980 ebb1ae0ba202b22ed14ec962b2d9535a 415 Gene3D G3DSA:1.20.1090.10 189 402 5.4E-56 T 22-04-2016 HRM2_RS00980 ebb1ae0ba202b22ed14ec962b2d9535a 415 Gene3D G3DSA:3.40.50.1970 7 188 3.2E-53 T 22-04-2016 HRM2_RS00980 ebb1ae0ba202b22ed14ec962b2d9535a 415 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 177 205 - T 22-04-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 HRM2_RS00980 ebb1ae0ba202b22ed14ec962b2d9535a 415 PANTHER PTHR11496 21 407 2.2E-88 T 22-04-2016 HRM2_RS06005 3f343c2f099ae52504aa2c1084977f05 567 PANTHER PTHR30269 426 567 1.4E-27 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 HRM2_RS06005 3f343c2f099ae52504aa2c1084977f05 567 PANTHER PTHR30269 259 400 1.4E-27 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 HRM2_RS06005 3f343c2f099ae52504aa2c1084977f05 567 Pfam PF01925 Sulfite exporter TauE/SafE 268 558 1.8E-30 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 HRM2_RS15060 678bc8fdb47e352cf8f9bee90bc23d80 354 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 27 255 5.8E-101 T 22-04-2016 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 HRM2_RS15060 678bc8fdb47e352cf8f9bee90bc23d80 354 Gene3D G3DSA:1.10.8.60 203 275 2.4E-28 T 22-04-2016 HRM2_RS15060 678bc8fdb47e352cf8f9bee90bc23d80 354 SUPERFAMILY SSF46785 277 348 5.17E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS15060 678bc8fdb47e352cf8f9bee90bc23d80 354 PANTHER PTHR13779:SF25 15 347 2.1E-148 T 22-04-2016 HRM2_RS15060 678bc8fdb47e352cf8f9bee90bc23d80 354 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 273 347 1.9E-26 T 22-04-2016 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 HRM2_RS15060 678bc8fdb47e352cf8f9bee90bc23d80 354 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 273 348 4.0E-17 T 22-04-2016 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 HRM2_RS15060 678bc8fdb47e352cf8f9bee90bc23d80 354 Gene3D G3DSA:3.40.50.300 40 192 1.0E-33 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS15060 678bc8fdb47e352cf8f9bee90bc23d80 354 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 354 138.811 T 22-04-2016 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 HRM2_RS15060 678bc8fdb47e352cf8f9bee90bc23d80 354 Gene3D G3DSA:1.10.10.10 277 348 1.0E-25 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS15060 678bc8fdb47e352cf8f9bee90bc23d80 354 SUPERFAMILY SSF52540 40 269 1.43E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS15060 678bc8fdb47e352cf8f9bee90bc23d80 354 SMART SM00382 71 204 4.3E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS15060 678bc8fdb47e352cf8f9bee90bc23d80 354 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 44 346 2.7E-124 T 22-04-2016 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 HRM2_RS15060 678bc8fdb47e352cf8f9bee90bc23d80 354 PANTHER PTHR13779 15 347 2.1E-148 T 22-04-2016 HRM2_RS16550 a3e382e1d3fc6fecb6665e19d960b281 230 Pfam PF00005 ABC transporter 21 147 1.8E-11 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS16550 a3e382e1d3fc6fecb6665e19d960b281 230 ProSitePatterns PS00211 ABC transporters family signature. 120 134 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS16550 a3e382e1d3fc6fecb6665e19d960b281 230 PANTHER PTHR24220 4 192 1.8E-22 T 22-04-2016 HRM2_RS16550 a3e382e1d3fc6fecb6665e19d960b281 230 Gene3D G3DSA:3.40.50.300 4 195 2.6E-30 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16550 a3e382e1d3fc6fecb6665e19d960b281 230 SUPERFAMILY SSF52540 3 193 4.42E-32 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13575 05d84b11e492d28f04f3cd6e99cc4635 443 PANTHER PTHR33362 1 443 3.0E-139 T 22-04-2016 HRM2_RS13575 05d84b11e492d28f04f3cd6e99cc4635 443 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 12 432 3.0E-86 T 22-04-2016 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit HRM2_RS13575 05d84b11e492d28f04f3cd6e99cc4635 443 PANTHER PTHR33362:SF7 1 443 3.0E-139 T 22-04-2016 HRM2_RS13575 05d84b11e492d28f04f3cd6e99cc4635 443 PIRSF PIRSF006066 8 443 7.8E-72 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS13575 05d84b11e492d28f04f3cd6e99cc4635 443 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 24 438 3.5E-93 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS12165 443af6304e66da77aadfc28652c69e8a 366 Gene3D G3DSA:3.30.460.10 16 178 2.0E-11 T 22-04-2016 HRM2_RS12165 443af6304e66da77aadfc28652c69e8a 366 PANTHER PTHR41773 7 192 2.5E-13 T 22-04-2016 HRM2_RS12165 443af6304e66da77aadfc28652c69e8a 366 Pfam PF04607 Region found in RelA / SpoT proteins 48 193 3.4E-16 T 22-04-2016 IPR007685 RelA/SpoT GO:0015969 HRM2_RS12165 443af6304e66da77aadfc28652c69e8a 366 SUPERFAMILY SSF81301 36 229 1.16E-19 T 22-04-2016 HRM2_RS12165 443af6304e66da77aadfc28652c69e8a 366 SMART SM00954 47 198 4.3E-6 T 22-04-2016 IPR007685 RelA/SpoT GO:0015969 HRM2_RS08945 79ab0162d89beacf1bee0de222ed059b 408 SMART SM00490 257 338 7.5E-30 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS08945 79ab0162d89beacf1bee0de222ed059b 408 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 152 160 - T 22-04-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site HRM2_RS08945 79ab0162d89beacf1bee0de222ed059b 408 PANTHER PTHR24031:SF0 1 375 4.4E-180 T 22-04-2016 HRM2_RS08945 79ab0162d89beacf1bee0de222ed059b 408 Gene3D G3DSA:3.40.50.300 211 364 7.1E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08945 79ab0162d89beacf1bee0de222ed059b 408 Pfam PF00271 Helicase conserved C-terminal domain 232 338 2.9E-26 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS08945 79ab0162d89beacf1bee0de222ed059b 408 SMART SM00487 20 221 4.9E-62 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS08945 79ab0162d89beacf1bee0de222ed059b 408 SUPERFAMILY SSF52540 73 358 5.19E-73 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08945 79ab0162d89beacf1bee0de222ed059b 408 Gene3D G3DSA:3.40.50.300 1 210 4.9E-79 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08945 79ab0162d89beacf1bee0de222ed059b 408 Pfam PF00270 DEAD/DEAH box helicase 26 194 2.7E-48 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HRM2_RS08945 79ab0162d89beacf1bee0de222ed059b 408 PANTHER PTHR24031 1 375 4.4E-180 T 22-04-2016 HRM2_RS05315 0413a8d51cd9e462aa5dbd8be0205dac 300 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 173 1.1E-32 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HRM2_RS05315 0413a8d51cd9e462aa5dbd8be0205dac 300 PANTHER PTHR11649 4 300 4.7E-111 T 22-04-2016 HRM2_RS05315 0413a8d51cd9e462aa5dbd8be0205dac 300 Pfam PF07650 KH domain 213 288 8.1E-20 T 22-04-2016 IPR004044 K Homology domain, type 2 GO:0003723 HRM2_RS05315 0413a8d51cd9e462aa5dbd8be0205dac 300 Pfam PF01926 50S ribosome-binding GTPase 16 130 6.8E-25 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS05315 0413a8d51cd9e462aa5dbd8be0205dac 300 Gene3D G3DSA:3.40.50.300 14 196 6.4E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05315 0413a8d51cd9e462aa5dbd8be0205dac 300 SUPERFAMILY SSF52540 16 210 4.68E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05315 0413a8d51cd9e462aa5dbd8be0205dac 300 PANTHER PTHR11649:SF3 4 300 4.7E-111 T 22-04-2016 HRM2_RS05315 0413a8d51cd9e462aa5dbd8be0205dac 300 SUPERFAMILY SSF54814 186 300 8.18E-40 T 22-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 HRM2_RS05315 0413a8d51cd9e462aa5dbd8be0205dac 300 Hamap MF_00367 GTPase Era [era]. 11 300 34.823 T 22-04-2016 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 HRM2_RS05315 0413a8d51cd9e462aa5dbd8be0205dac 300 Gene3D G3DSA:3.30.300.20 197 297 8.2E-39 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta HRM2_RS05315 0413a8d51cd9e462aa5dbd8be0205dac 300 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 83 101 1.4E-6 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS05315 0413a8d51cd9e462aa5dbd8be0205dac 300 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 16 36 1.4E-6 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS05315 0413a8d51cd9e462aa5dbd8be0205dac 300 TIGRFAM TIGR00436 era: GTP-binding protein Era 14 283 4.3E-90 T 22-04-2016 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 HRM2_RS06160 27f3dcbd29ccd7863a41caa62936e662 1391 SUPERFAMILY SSF56059 899 1250 7.06E-83 T 22-04-2016 HRM2_RS06160 27f3dcbd29ccd7863a41caa62936e662 1391 PANTHER PTHR22931 821 1382 8.6E-128 T 22-04-2016 HRM2_RS06160 27f3dcbd29ccd7863a41caa62936e662 1391 SUPERFAMILY SSF52009 1265 1387 8.5E-26 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS06160 27f3dcbd29ccd7863a41caa62936e662 1391 Pfam PF00391 PEP-utilising enzyme, mobile domain 1300 1379 9.5E-18 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS06160 27f3dcbd29ccd7863a41caa62936e662 1391 PANTHER PTHR22931:SF28 821 1382 8.6E-128 T 22-04-2016 HRM2_RS06160 27f3dcbd29ccd7863a41caa62936e662 1391 Gene3D G3DSA:3.30.1490.20 899 999 2.3E-41 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HRM2_RS06160 27f3dcbd29ccd7863a41caa62936e662 1391 Gene3D G3DSA:3.30.1490.20 1086 1129 2.3E-41 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HRM2_RS06160 27f3dcbd29ccd7863a41caa62936e662 1391 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 948 1175 2.0E-22 T 22-04-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 HRM2_RS06160 27f3dcbd29ccd7863a41caa62936e662 1391 Gene3D G3DSA:3.50.30.10 1265 1382 6.7E-28 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS06160 27f3dcbd29ccd7863a41caa62936e662 1391 Gene3D G3DSA:1.20.80.30 1000 1078 1.2E-18 T 22-04-2016 HRM2_RS06160 27f3dcbd29ccd7863a41caa62936e662 1391 Gene3D G3DSA:3.30.470.20 1130 1244 1.1E-15 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS01225 8ea184d1401fabdf63cbb79cb79d1712 291 SUPERFAMILY SSF48179 169 271 1.84E-27 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HRM2_RS01225 8ea184d1401fabdf63cbb79cb79d1712 291 Gene3D G3DSA:3.40.50.720 3 166 4.7E-38 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS01225 8ea184d1401fabdf63cbb79cb79d1712 291 PANTHER PTHR40459:SF1 1 269 1.8E-56 T 22-04-2016 HRM2_RS01225 8ea184d1401fabdf63cbb79cb79d1712 291 Pfam PF10727 Rossmann-like domain 5 108 1.6E-12 T 22-04-2016 IPR019665 Putative oxidoreductase/dehydrogenase, Rossmann-like domain HRM2_RS01225 8ea184d1401fabdf63cbb79cb79d1712 291 PANTHER PTHR40459 1 269 1.8E-56 T 22-04-2016 HRM2_RS01225 8ea184d1401fabdf63cbb79cb79d1712 291 Gene3D G3DSA:1.10.1040.20 169 269 9.2E-32 T 22-04-2016 IPR018931 Domain of unknown function DUF2520 HRM2_RS01225 8ea184d1401fabdf63cbb79cb79d1712 291 Pfam PF10728 Domain of unknown function (DUF2520) 138 264 2.9E-37 T 22-04-2016 IPR018931 Domain of unknown function DUF2520 HRM2_RS01225 8ea184d1401fabdf63cbb79cb79d1712 291 SUPERFAMILY SSF51735 5 166 4.4E-25 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS01855 7d5d9b45a130fe71621394a911c794c4 117 Pfam PF05717 IS66 Orf2 like protein 9 106 1.6E-41 T 22-04-2016 IPR008878 Transposase IS66, Orf2 HRM2_RS01855 7d5d9b45a130fe71621394a911c794c4 117 PANTHER PTHR36455 2 113 2.8E-36 T 22-04-2016 HRM2_RS01855 7d5d9b45a130fe71621394a911c794c4 117 PANTHER PTHR36455:SF1 2 113 2.8E-36 T 22-04-2016 HRM2_RS21555 7d5d9b45a130fe71621394a911c794c4 117 Pfam PF05717 IS66 Orf2 like protein 9 106 1.6E-41 T 22-04-2016 IPR008878 Transposase IS66, Orf2 HRM2_RS21555 7d5d9b45a130fe71621394a911c794c4 117 PANTHER PTHR36455 2 113 2.8E-36 T 22-04-2016 HRM2_RS21555 7d5d9b45a130fe71621394a911c794c4 117 PANTHER PTHR36455:SF1 2 113 2.8E-36 T 22-04-2016 HRM2_RS15295 949b2395f29ff9c1db9569e5339ed586 250 PANTHER PTHR32125 1 96 8.1E-101 T 22-04-2016 HRM2_RS15295 949b2395f29ff9c1db9569e5339ed586 250 PANTHER PTHR32125 112 228 8.1E-101 T 22-04-2016 HRM2_RS15295 949b2395f29ff9c1db9569e5339ed586 250 SUPERFAMILY SSF75217 2 244 1.57E-92 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases HRM2_RS15295 949b2395f29ff9c1db9569e5339ed586 250 Gene3D G3DSA:1.10.1270.20 163 244 9.9E-29 T 22-04-2016 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 HRM2_RS15295 949b2395f29ff9c1db9569e5339ed586 250 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 250 101.023 T 22-04-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 HRM2_RS15295 949b2395f29ff9c1db9569e5339ed586 250 PANTHER PTHR32125:SF1 1 96 8.1E-101 T 22-04-2016 HRM2_RS15295 949b2395f29ff9c1db9569e5339ed586 250 PANTHER PTHR32125:SF1 112 228 8.1E-101 T 22-04-2016 HRM2_RS15295 949b2395f29ff9c1db9569e5339ed586 250 Gene3D G3DSA:3.40.1280.10 2 160 9.7E-64 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HRM2_RS15295 949b2395f29ff9c1db9569e5339ed586 250 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 221 3.7E-59 T 22-04-2016 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 HRM2_RS15295 949b2395f29ff9c1db9569e5339ed586 250 PIRSF PIRSF000386 1 249 6.4E-95 T 22-04-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 HRM2_RS15295 949b2395f29ff9c1db9569e5339ed586 250 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 2 233 1.4E-90 T 22-04-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 HRM2_RS22625 8886abe6600dd501910bf526d562976a 340 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 6 339 1.3E-96 T 22-04-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 HRM2_RS22625 8886abe6600dd501910bf526d562976a 340 Gene3D G3DSA:2.40.30.10 263 339 2.2E-21 T 22-04-2016 HRM2_RS22625 8886abe6600dd501910bf526d562976a 340 PANTHER PTHR11933 7 340 2.0E-125 T 22-04-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 HRM2_RS22625 8886abe6600dd501910bf526d562976a 340 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 3 340 36.302 T 22-04-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 HRM2_RS22625 8886abe6600dd501910bf526d562976a 340 SUPERFAMILY SSF52402 6 233 9.26E-48 T 22-04-2016 HRM2_RS22625 8886abe6600dd501910bf526d562976a 340 Gene3D G3DSA:2.30.30.280 204 261 1.4E-18 T 22-04-2016 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 HRM2_RS22625 8886abe6600dd501910bf526d562976a 340 Pfam PF03054 tRNA methyl transferase 6 339 1.8E-101 T 22-04-2016 HRM2_RS22625 8886abe6600dd501910bf526d562976a 340 PANTHER PTHR11933:SF10 7 340 2.0E-125 T 22-04-2016 HRM2_RS22625 8886abe6600dd501910bf526d562976a 340 Gene3D G3DSA:3.40.50.620 6 197 4.9E-69 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS18670 256904ef1bd460340d399cee42f13cee 470 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 167 180 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS18670 256904ef1bd460340d399cee42f13cee 470 PANTHER PTHR32071 8 467 1.8E-163 T 22-04-2016 HRM2_RS18670 256904ef1bd460340d399cee42f13cee 470 Gene3D G3DSA:1.10.10.60 410 451 9.2E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS18670 256904ef1bd460340d399cee42f13cee 470 Pfam PF00158 Sigma-54 interaction domain 143 310 4.7E-62 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS18670 256904ef1bd460340d399cee42f13cee 470 SMART SM00448 4 114 4.6E-35 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18670 256904ef1bd460340d399cee42f13cee 470 SUPERFAMILY SSF52540 142 385 5.33E-65 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18670 256904ef1bd460340d399cee42f13cee 470 SUPERFAMILY SSF46689 357 451 2.91E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS18670 256904ef1bd460340d399cee42f13cee 470 SMART SM00382 163 307 7.9E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS18670 256904ef1bd460340d399cee42f13cee 470 SUPERFAMILY SSF52172 3 187 1.99E-41 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS18670 256904ef1bd460340d399cee42f13cee 470 Pfam PF00072 Response regulator receiver domain 7 111 4.7E-27 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18670 256904ef1bd460340d399cee42f13cee 470 Gene3D G3DSA:3.40.50.300 142 315 1.5E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18670 256904ef1bd460340d399cee42f13cee 470 Gene3D G3DSA:1.10.8.60 317 385 9.7E-22 T 22-04-2016 HRM2_RS18670 256904ef1bd460340d399cee42f13cee 470 Gene3D G3DSA:3.40.50.2300 5 133 1.2E-33 T 22-04-2016 HRM2_RS15270 1b1b10a6f652984a68d01d74e2dc2119 294 Gene3D G3DSA:3.30.950.10 123 235 1.8E-38 T 22-04-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 HRM2_RS15270 1b1b10a6f652984a68d01d74e2dc2119 294 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 93 104 - T 22-04-2016 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HRM2_RS15270 1b1b10a6f652984a68d01d74e2dc2119 294 SUPERFAMILY SSF53790 14 232 5.89E-79 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 HRM2_RS15270 1b1b10a6f652984a68d01d74e2dc2119 294 PANTHER PTHR21091:SF18 14 253 1.1E-87 T 22-04-2016 HRM2_RS15270 1b1b10a6f652984a68d01d74e2dc2119 294 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 15 214 1.1E-26 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 HRM2_RS15270 1b1b10a6f652984a68d01d74e2dc2119 294 PIRSF PIRSF005917 7 291 4.3E-101 T 22-04-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HRM2_RS15270 1b1b10a6f652984a68d01d74e2dc2119 294 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 15 234 37.748 T 22-04-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HRM2_RS15270 1b1b10a6f652984a68d01d74e2dc2119 294 PANTHER PTHR21091 14 253 1.1E-87 T 22-04-2016 HRM2_RS15270 1b1b10a6f652984a68d01d74e2dc2119 294 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 16 286 2.3E-80 T 22-04-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HRM2_RS15270 1b1b10a6f652984a68d01d74e2dc2119 294 Gene3D G3DSA:3.40.1010.10 14 122 1.0E-16 T 22-04-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 HRM2_RS05920 1e29d96ada55cd106251b4c96c5c88f0 545 Gene3D G3DSA:3.40.50.980 201 362 2.4E-33 T 22-04-2016 HRM2_RS05920 1e29d96ada55cd106251b4c96c5c88f0 545 Gene3D G3DSA:2.30.38.10 363 439 2.8E-21 T 22-04-2016 HRM2_RS05920 1e29d96ada55cd106251b4c96c5c88f0 545 PANTHER PTHR24095:SF180 9 543 4.0E-198 T 22-04-2016 HRM2_RS05920 1e29d96ada55cd106251b4c96c5c88f0 545 ProSitePatterns PS00455 Putative AMP-binding domain signature. 195 206 - T 22-04-2016 IPR020845 AMP-binding, conserved site HRM2_RS05920 1e29d96ada55cd106251b4c96c5c88f0 545 Pfam PF00501 AMP-binding enzyme 35 446 1.8E-80 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS05920 1e29d96ada55cd106251b4c96c5c88f0 545 Pfam PF13193 AMP-binding enzyme C-terminal domain 455 533 1.1E-21 T 22-04-2016 IPR025110 AMP-binding enzyme C-terminal domain HRM2_RS05920 1e29d96ada55cd106251b4c96c5c88f0 545 SUPERFAMILY SSF56801 13 542 3.27E-145 T 22-04-2016 HRM2_RS05920 1e29d96ada55cd106251b4c96c5c88f0 545 Gene3D G3DSA:3.40.50.980 29 200 3.2E-27 T 22-04-2016 HRM2_RS05920 1e29d96ada55cd106251b4c96c5c88f0 545 PANTHER PTHR24095 9 543 4.0E-198 T 22-04-2016 HRM2_RS05920 1e29d96ada55cd106251b4c96c5c88f0 545 Gene3D G3DSA:3.30.300.30 441 542 3.1E-29 T 22-04-2016 HRM2_RS06295 0facbb6f40fd43a055cd0d78b7811749 458 Pfam PF02875 Mur ligase family, glutamate ligase domain 318 386 1.3E-8 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HRM2_RS06295 0facbb6f40fd43a055cd0d78b7811749 458 SUPERFAMILY SSF53244 316 453 5.72E-40 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HRM2_RS06295 0facbb6f40fd43a055cd0d78b7811749 458 PANTHER PTHR23135 19 456 1.5E-136 T 22-04-2016 HRM2_RS06295 0facbb6f40fd43a055cd0d78b7811749 458 SUPERFAMILY SSF51984 19 105 3.27E-13 T 22-04-2016 HRM2_RS06295 0facbb6f40fd43a055cd0d78b7811749 458 Gene3D G3DSA:3.40.1190.10 106 316 4.8E-51 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HRM2_RS06295 0facbb6f40fd43a055cd0d78b7811749 458 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 19 450 1.3E-123 T 22-04-2016 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS06295 0facbb6f40fd43a055cd0d78b7811749 458 Gene3D G3DSA:3.40.50.720 19 104 3.0E-16 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS06295 0facbb6f40fd43a055cd0d78b7811749 458 Gene3D G3DSA:3.90.190.20 318 449 1.6E-44 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HRM2_RS06295 0facbb6f40fd43a055cd0d78b7811749 458 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 17 453 32.231 T 22-04-2016 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS06295 0facbb6f40fd43a055cd0d78b7811749 458 SUPERFAMILY SSF53623 110 314 1.83E-44 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HRM2_RS06295 0facbb6f40fd43a055cd0d78b7811749 458 Pfam PF08245 Mur ligase middle domain 122 297 2.4E-31 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HRM2_RS06295 0facbb6f40fd43a055cd0d78b7811749 458 PANTHER PTHR23135:SF2 19 456 1.5E-136 T 22-04-2016 HRM2_RS18755 d915325a0763905ca4045f5c3f452a3f 769 SUPERFAMILY SSF56003 135 761 4.06E-162 T 22-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 HRM2_RS18755 d915325a0763905ca4045f5c3f452a3f 769 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 147 701 1.6E-144 T 22-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 HRM2_RS18755 d915325a0763905ca4045f5c3f452a3f 769 SMART SM01008 24 130 1.2E-35 T 22-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead HRM2_RS18755 d915325a0763905ca4045f5c3f452a3f 769 Gene3D G3DSA:3.90.1170.50 4 118 1.4E-32 T 22-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead HRM2_RS18755 d915325a0763905ca4045f5c3f452a3f 769 Gene3D G3DSA:3.30.365.10 174 280 3.6E-32 T 22-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 HRM2_RS18755 d915325a0763905ca4045f5c3f452a3f 769 Gene3D G3DSA:3.30.365.10 629 763 1.1E-53 T 22-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 HRM2_RS18755 d915325a0763905ca4045f5c3f452a3f 769 Gene3D G3DSA:3.30.365.10 358 450 1.1E-53 T 22-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 HRM2_RS18755 d915325a0763905ca4045f5c3f452a3f 769 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 25 129 5.5E-19 T 22-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead HRM2_RS18755 d915325a0763905ca4045f5c3f452a3f 769 PANTHER PTHR11908 10 547 8.0E-183 T 22-04-2016 HRM2_RS18755 d915325a0763905ca4045f5c3f452a3f 769 PANTHER PTHR11908 567 766 8.0E-183 T 22-04-2016 HRM2_RS18755 d915325a0763905ca4045f5c3f452a3f 769 SUPERFAMILY SSF54665 7 149 1.7E-33 T 22-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead HRM2_RS18755 d915325a0763905ca4045f5c3f452a3f 769 Gene3D G3DSA:3.30.365.10 456 628 2.0E-26 T 22-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 HRM2_RS18755 d915325a0763905ca4045f5c3f452a3f 769 Gene3D G3DSA:3.30.365.10 282 356 1.8E-33 T 22-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 HRM2_RS18755 d915325a0763905ca4045f5c3f452a3f 769 Gene3D G3DSA:3.30.365.10 119 173 1.8E-33 T 22-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 HRM2_RS08450 35f881eda90c90e77648c98f9d5f5581 574 SMART SM01049 45 136 6.5E-8 T 22-04-2016 IPR033480 Single Cache domain 2 HRM2_RS08450 35f881eda90c90e77648c98f9d5f5581 574 PANTHER PTHR32089 150 574 1.8E-96 T 22-04-2016 HRM2_RS08450 35f881eda90c90e77648c98f9d5f5581 574 Gene3D G3DSA:3.30.450.20 40 187 6.2E-32 T 22-04-2016 HRM2_RS08450 35f881eda90c90e77648c98f9d5f5581 574 Pfam PF17200 Single Cache domain 2 78 193 6.2E-24 T 22-04-2016 IPR033480 Single Cache domain 2 HRM2_RS08450 35f881eda90c90e77648c98f9d5f5581 574 SMART SM00304 345 401 100.0 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS08450 35f881eda90c90e77648c98f9d5f5581 574 SMART SM00304 228 282 7.1E-7 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS08450 35f881eda90c90e77648c98f9d5f5581 574 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 376 571 3.6E-37 T 22-04-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HRM2_RS08450 35f881eda90c90e77648c98f9d5f5581 574 SMART SM00283 297 572 3.3E-49 T 22-04-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HRM2_RS08450 35f881eda90c90e77648c98f9d5f5581 574 SUPERFAMILY SSF58104 250 571 9.68E-66 T 22-04-2016 HRM2_RS08450 35f881eda90c90e77648c98f9d5f5581 574 Pfam PF00672 HAMP domain 209 278 1.5E-8 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS08450 35f881eda90c90e77648c98f9d5f5581 574 Gene3D G3DSA:1.10.287.950 319 529 7.4E-47 T 22-04-2016 HRM2_RS19435 c2f19ac288bf4251d99ae407e80cd56b 492 SUPERFAMILY SSF55874 177 351 3.01E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS19435 c2f19ac288bf4251d99ae407e80cd56b 492 SUPERFAMILY SSF47384 111 184 5.89E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS19435 c2f19ac288bf4251d99ae407e80cd56b 492 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 7 105 4.1E-9 T 22-04-2016 IPR000014 PAS domain HRM2_RS19435 c2f19ac288bf4251d99ae407e80cd56b 492 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 229 349 1.0E-18 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS19435 c2f19ac288bf4251d99ae407e80cd56b 492 PANTHER PTHR24423 8 489 3.8E-170 T 22-04-2016 HRM2_RS19435 c2f19ac288bf4251d99ae407e80cd56b 492 Pfam PF00072 Response regulator receiver domain 372 484 1.5E-17 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS19435 c2f19ac288bf4251d99ae407e80cd56b 492 Gene3D G3DSA:3.30.565.10 173 352 5.7E-40 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS19435 c2f19ac288bf4251d99ae407e80cd56b 492 Gene3D G3DSA:1.10.287.130 115 172 1.6E-5 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS19435 c2f19ac288bf4251d99ae407e80cd56b 492 SUPERFAMILY SSF55785 8 104 9.5E-11 T 22-04-2016 IPR000014 PAS domain HRM2_RS19435 c2f19ac288bf4251d99ae407e80cd56b 492 Gene3D G3DSA:3.40.50.2300 369 489 5.1E-29 T 22-04-2016 HRM2_RS19435 c2f19ac288bf4251d99ae407e80cd56b 492 SMART SM00086 61 99 0.005 T 22-04-2016 IPR001610 PAC motif HRM2_RS19435 c2f19ac288bf4251d99ae407e80cd56b 492 SMART SM00387 228 351 2.4E-24 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS19435 c2f19ac288bf4251d99ae407e80cd56b 492 SUPERFAMILY SSF52172 370 489 1.57E-25 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS19435 c2f19ac288bf4251d99ae407e80cd56b 492 PANTHER PTHR24423:SF458 8 489 3.8E-170 T 22-04-2016 HRM2_RS19435 c2f19ac288bf4251d99ae407e80cd56b 492 Gene3D G3DSA:3.30.450.20 8 101 3.5E-11 T 22-04-2016 HRM2_RS19435 c2f19ac288bf4251d99ae407e80cd56b 492 Pfam PF13426 PAS domain 7 98 8.8E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS19435 c2f19ac288bf4251d99ae407e80cd56b 492 SMART SM00388 121 187 6.5E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS19435 c2f19ac288bf4251d99ae407e80cd56b 492 Pfam PF00512 His Kinase A (phospho-acceptor) domain 122 185 1.6E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS19435 c2f19ac288bf4251d99ae407e80cd56b 492 SMART SM00448 370 484 3.2E-19 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS19435 c2f19ac288bf4251d99ae407e80cd56b 492 PRINTS PR00344 Bacterial sensor protein C-terminal signature 311 329 6.9E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS19435 c2f19ac288bf4251d99ae407e80cd56b 492 PRINTS PR00344 Bacterial sensor protein C-terminal signature 298 308 6.9E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS19435 c2f19ac288bf4251d99ae407e80cd56b 492 PRINTS PR00344 Bacterial sensor protein C-terminal signature 280 294 6.9E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS19435 c2f19ac288bf4251d99ae407e80cd56b 492 PRINTS PR00344 Bacterial sensor protein C-terminal signature 335 348 6.9E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS11585 e3ad2fe32ad93f3f454e816ad4825bc4 606 PANTHER PTHR30562:SF1 7 601 3.0E-232 T 22-04-2016 HRM2_RS11585 e3ad2fe32ad93f3f454e816ad4825bc4 606 SUPERFAMILY SSF46600 190 242 3.92E-10 T 22-04-2016 IPR001943 UVR domain GO:0005515 HRM2_RS11585 e3ad2fe32ad93f3f454e816ad4825bc4 606 SUPERFAMILY SSF82771 16 99 1.44E-20 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily HRM2_RS11585 e3ad2fe32ad93f3f454e816ad4825bc4 606 Pfam PF02151 UvrB/uvrC motif 205 236 1.1E-6 T 22-04-2016 IPR001943 UVR domain GO:0005515 HRM2_RS11585 e3ad2fe32ad93f3f454e816ad4825bc4 606 Gene3D G3DSA:4.10.860.10 182 242 1.4E-13 T 22-04-2016 IPR001943 UVR domain GO:0005515 HRM2_RS11585 e3ad2fe32ad93f3f454e816ad4825bc4 606 SUPERFAMILY SSF47781 516 602 1.68E-16 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 HRM2_RS11585 e3ad2fe32ad93f3f454e816ad4825bc4 606 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 7 582 9.3E-172 T 22-04-2016 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 HRM2_RS11585 e3ad2fe32ad93f3f454e816ad4825bc4 606 Gene3D G3DSA:1.10.150.20 548 601 6.4E-15 T 22-04-2016 HRM2_RS11585 e3ad2fe32ad93f3f454e816ad4825bc4 606 SMART SM00465 15 97 9.2E-21 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily HRM2_RS11585 e3ad2fe32ad93f3f454e816ad4825bc4 606 Hamap MF_00203 UvrABC system protein C [uvrC]. 2 600 27.324 T 22-04-2016 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 HRM2_RS11585 e3ad2fe32ad93f3f454e816ad4825bc4 606 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 381 535 7.1E-48 T 22-04-2016 IPR001162 UvrC family homology region HRM2_RS11585 e3ad2fe32ad93f3f454e816ad4825bc4 606 Pfam PF01541 GIY-YIG catalytic domain 16 92 1.0E-10 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily HRM2_RS11585 e3ad2fe32ad93f3f454e816ad4825bc4 606 PANTHER PTHR30562 7 601 3.0E-232 T 22-04-2016 HRM2_RS11585 e3ad2fe32ad93f3f454e816ad4825bc4 606 Gene3D G3DSA:3.40.1440.10 15 94 2.2E-9 T 22-04-2016 IPR027299 GIY-YIG domain HRM2_RS17020 8a039eb4db3ade9b4550225d454887a1 348 PANTHER PTHR24421:SF4 5 348 2.3E-139 T 22-04-2016 HRM2_RS17020 8a039eb4db3ade9b4550225d454887a1 348 SMART SM00448 5 126 2.1E-20 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS17020 8a039eb4db3ade9b4550225d454887a1 348 Pfam PF00072 Response regulator receiver domain 7 111 1.8E-22 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS17020 8a039eb4db3ade9b4550225d454887a1 348 SUPERFAMILY SSF52172 3 113 1.57E-26 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS17020 8a039eb4db3ade9b4550225d454887a1 348 Gene3D G3DSA:3.40.50.180 158 346 5.8E-78 T 22-04-2016 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 HRM2_RS17020 8a039eb4db3ade9b4550225d454887a1 348 PIRSF PIRSF000876 2 348 1.8E-127 T 22-04-2016 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 HRM2_RS17020 8a039eb4db3ade9b4550225d454887a1 348 PANTHER PTHR24421 5 348 2.3E-139 T 22-04-2016 HRM2_RS17020 8a039eb4db3ade9b4550225d454887a1 348 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 5 346 38.736 T 22-04-2016 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 HRM2_RS17020 8a039eb4db3ade9b4550225d454887a1 348 Gene3D G3DSA:3.40.50.2300 3 140 3.1E-27 T 22-04-2016 HRM2_RS17020 8a039eb4db3ade9b4550225d454887a1 348 Pfam PF01339 CheB methylesterase 163 339 6.6E-60 T 22-04-2016 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 HRM2_RS17020 8a039eb4db3ade9b4550225d454887a1 348 SUPERFAMILY SSF52738 159 345 2.22E-69 T 22-04-2016 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 HRM2_RS21505 0865137e0a5e4f636fd05da3e38cfe7d 249 Gene3D G3DSA:3.60.15.10 2 224 7.2E-36 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS21505 0865137e0a5e4f636fd05da3e38cfe7d 249 PANTHER PTHR13754:SF13 5 241 3.5E-56 T 22-04-2016 HRM2_RS21505 0865137e0a5e4f636fd05da3e38cfe7d 249 SUPERFAMILY SSF56281 25 241 1.65E-31 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS21505 0865137e0a5e4f636fd05da3e38cfe7d 249 PANTHER PTHR13754 5 241 3.5E-56 T 22-04-2016 HRM2_RS21505 0865137e0a5e4f636fd05da3e38cfe7d 249 SMART SM00849 25 212 1.3E-4 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS21505 0865137e0a5e4f636fd05da3e38cfe7d 249 Pfam PF00753 Metallo-beta-lactamase superfamily 27 88 1.3E-10 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS24915 05e31f34a836a116bb75e24a9ef7489e 581 Gene3D G3DSA:1.10.101.10 502 566 4.8E-8 T 22-04-2016 IPR002477 Peptidoglycan binding-like HRM2_RS24915 05e31f34a836a116bb75e24a9ef7489e 581 SMART SM00382 42 195 1.6E-6 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS24915 05e31f34a836a116bb75e24a9ef7489e 581 SUPERFAMILY SSF52540 12 265 7.49E-30 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24915 05e31f34a836a116bb75e24a9ef7489e 581 Pfam PF01471 Putative peptidoglycan binding domain 508 560 1.0E-6 T 22-04-2016 IPR002477 Peptidoglycan binding-like HRM2_RS24915 05e31f34a836a116bb75e24a9ef7489e 581 Gene3D G3DSA:3.40.50.300 28 182 8.2E-19 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24915 05e31f34a836a116bb75e24a9ef7489e 581 PANTHER PTHR35894 2 265 1.2E-98 T 22-04-2016 HRM2_RS24915 05e31f34a836a116bb75e24a9ef7489e 581 Pfam PF13401 AAA domain 42 170 4.3E-21 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS24915 05e31f34a836a116bb75e24a9ef7489e 581 SUPERFAMILY SSF47090 500 564 2.25E-9 T 22-04-2016 IPR002477 Peptidoglycan binding-like HRM2_RS24915 05e31f34a836a116bb75e24a9ef7489e 581 PANTHER PTHR35894:SF1 2 265 1.2E-98 T 22-04-2016 HRM2_RS19755 abd4fc8ae910ff9daf8df5841915f7da 571 Gene3D G3DSA:3.30.300.30 443 555 1.9E-12 T 22-04-2016 HRM2_RS19755 abd4fc8ae910ff9daf8df5841915f7da 571 Gene3D G3DSA:3.40.50.980 2 164 8.3E-27 T 22-04-2016 HRM2_RS19755 abd4fc8ae910ff9daf8df5841915f7da 571 SUPERFAMILY SSF56801 359 560 1.44E-92 T 22-04-2016 HRM2_RS19755 abd4fc8ae910ff9daf8df5841915f7da 571 SUPERFAMILY SSF56801 2 332 1.44E-92 T 22-04-2016 HRM2_RS19755 abd4fc8ae910ff9daf8df5841915f7da 571 Pfam PF00501 AMP-binding enzyme 9 451 1.2E-62 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS19755 abd4fc8ae910ff9daf8df5841915f7da 571 ProSitePatterns PS00455 Putative AMP-binding domain signature. 158 169 - T 22-04-2016 IPR020845 AMP-binding, conserved site HRM2_RS19755 abd4fc8ae910ff9daf8df5841915f7da 571 PANTHER PTHR22754 1 567 7.0E-154 T 22-04-2016 HRM2_RS19755 abd4fc8ae910ff9daf8df5841915f7da 571 Gene3D G3DSA:3.40.50.980 165 322 2.9E-31 T 22-04-2016 HRM2_RS19755 abd4fc8ae910ff9daf8df5841915f7da 571 Gene3D G3DSA:2.30.38.10 363 441 2.2E-13 T 22-04-2016 HRM2_RS22630 cdeba3b8ce493a6b8fefe4889fb7d499 143 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 116 127 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS22630 cdeba3b8ce493a6b8fefe4889fb7d499 143 SMART SM00930 2 74 8.8E-6 T 22-04-2016 IPR018449 NIL domain HRM2_RS22630 cdeba3b8ce493a6b8fefe4889fb7d499 143 Pfam PF09383 NIL domain 5 71 6.1E-10 T 22-04-2016 IPR018449 NIL domain HRM2_RS22630 cdeba3b8ce493a6b8fefe4889fb7d499 143 SUPERFAMILY SSF55021 4 72 4.69E-12 T 22-04-2016 HRM2_RS22630 cdeba3b8ce493a6b8fefe4889fb7d499 143 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 85 96 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS22630 cdeba3b8ce493a6b8fefe4889fb7d499 143 Gene3D G3DSA:3.30.70.260 4 62 3.8E-11 T 22-04-2016 HRM2_RS22630 cdeba3b8ce493a6b8fefe4889fb7d499 143 SUPERFAMILY SSF54862 70 134 6.98E-18 T 22-04-2016 HRM2_RS22630 cdeba3b8ce493a6b8fefe4889fb7d499 143 Gene3D G3DSA:1.10.1060.10 63 88 2.4E-5 T 22-04-2016 HRM2_RS22630 cdeba3b8ce493a6b8fefe4889fb7d499 143 Gene3D G3DSA:3.30.70.20 89 133 2.3E-14 T 22-04-2016 HRM2_RS22630 cdeba3b8ce493a6b8fefe4889fb7d499 143 Pfam PF00037 4Fe-4S binding domain 109 130 1.5E-5 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS22630 cdeba3b8ce493a6b8fefe4889fb7d499 143 Pfam PF00037 4Fe-4S binding domain 80 100 1.6E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS00875 36f5c0dc7c7fd1a81c18c8de93baca02 815 Pfam PF13439 Glycosyltransferase Family 4 423 592 3.7E-7 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain HRM2_RS00875 36f5c0dc7c7fd1a81c18c8de93baca02 815 Gene3D G3DSA:3.40.50.2000 589 769 2.6E-26 T 22-04-2016 HRM2_RS00875 36f5c0dc7c7fd1a81c18c8de93baca02 815 Gene3D G3DSA:3.20.20.140 1 100 6.7E-8 T 22-04-2016 HRM2_RS00875 36f5c0dc7c7fd1a81c18c8de93baca02 815 Pfam PF00534 Glycosyl transferases group 1 616 761 1.4E-28 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 HRM2_RS00875 36f5c0dc7c7fd1a81c18c8de93baca02 815 PANTHER PTHR12526:SF363 183 787 2.8E-48 T 22-04-2016 HRM2_RS00875 36f5c0dc7c7fd1a81c18c8de93baca02 815 SUPERFAMILY SSF53756 417 785 2.83E-62 T 22-04-2016 HRM2_RS00875 36f5c0dc7c7fd1a81c18c8de93baca02 815 SUPERFAMILY SSF89550 195 238 1.28E-14 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 HRM2_RS00875 36f5c0dc7c7fd1a81c18c8de93baca02 815 SUPERFAMILY SSF89550 1 158 1.28E-14 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 HRM2_RS00875 36f5c0dc7c7fd1a81c18c8de93baca02 815 PANTHER PTHR12526 183 787 2.8E-48 T 22-04-2016 HRM2_RS20850 54f77bd361ea3a404ddac458115e55da 426 TIGRFAM TIGR03378 glycerol3P_GlpB: glycerol-3-phosphate dehydrogenase, anaerobic, B subunit 9 419 1.0E-64 T 22-04-2016 IPR009158 Glycerol-3-phosphate dehydrogenase, GlpB subunit GO:0004368|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|UniPathway: UPA00618 HRM2_RS20850 54f77bd361ea3a404ddac458115e55da 426 Gene3D G3DSA:3.50.50.60 7 72 9.9E-17 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS20850 54f77bd361ea3a404ddac458115e55da 426 Gene3D G3DSA:3.50.50.60 219 419 9.9E-17 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS20850 54f77bd361ea3a404ddac458115e55da 426 PIRSF PIRSF000141 6 425 6.9E-93 T 22-04-2016 IPR009158 Glycerol-3-phosphate dehydrogenase, GlpB subunit GO:0004368|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|UniPathway: UPA00618 HRM2_RS20850 54f77bd361ea3a404ddac458115e55da 426 SUPERFAMILY SSF51905 1 75 5.04E-18 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS20850 54f77bd361ea3a404ddac458115e55da 426 SUPERFAMILY SSF51905 252 419 5.04E-18 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS20850 54f77bd361ea3a404ddac458115e55da 426 SUPERFAMILY SSF51905 191 225 5.04E-18 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS20850 54f77bd361ea3a404ddac458115e55da 426 Pfam PF00890 FAD binding domain 9 407 4.1E-21 T 22-04-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain HRM2_RS02500 40f9e00203ab381589f4d5302f2d7635 293 SUPERFAMILY SSF51717 6 286 4.45E-100 T 22-04-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 HRM2_RS02500 40f9e00203ab381589f4d5302f2d7635 293 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 20 35 - T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 HRM2_RS02500 40f9e00203ab381589f4d5302f2d7635 293 PANTHER PTHR20941:SF1 11 289 1.4E-122 T 22-04-2016 HRM2_RS02500 40f9e00203ab381589f4d5302f2d7635 293 Pfam PF00809 Pterin binding enzyme 21 269 3.8E-86 T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 HRM2_RS02500 40f9e00203ab381589f4d5302f2d7635 293 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 20 280 1.8E-97 T 22-04-2016 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614|UniPathway: UPA00077 HRM2_RS02500 40f9e00203ab381589f4d5302f2d7635 293 Gene3D G3DSA:3.20.20.20 15 286 1.3E-108 T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 HRM2_RS02500 40f9e00203ab381589f4d5302f2d7635 293 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 54 67 - T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 HRM2_RS02500 40f9e00203ab381589f4d5302f2d7635 293 PANTHER PTHR20941 11 289 1.4E-122 T 22-04-2016 HRM2_RS11035 98ae44d5b877074f4ffd347baba29411 448 SUPERFAMILY SSF158472 165 212 1.57E-8 T 22-04-2016 HRM2_RS11035 98ae44d5b877074f4ffd347baba29411 448 SMART SM00387 331 444 3.5E-33 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS11035 98ae44d5b877074f4ffd347baba29411 448 SMART SM00388 217 285 4.8E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS11035 98ae44d5b877074f4ffd347baba29411 448 Gene3D G3DSA:3.30.565.10 273 443 1.2E-41 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS11035 98ae44d5b877074f4ffd347baba29411 448 SUPERFAMILY SSF47384 200 285 7.46E-17 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS11035 98ae44d5b877074f4ffd347baba29411 448 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 331 443 4.3E-25 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS11035 98ae44d5b877074f4ffd347baba29411 448 SMART SM00304 164 216 9.0E-9 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS11035 98ae44d5b877074f4ffd347baba29411 448 SUPERFAMILY SSF55874 274 442 5.5E-42 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS11035 98ae44d5b877074f4ffd347baba29411 448 Pfam PF00512 His Kinase A (phospho-acceptor) domain 218 285 4.3E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS11035 98ae44d5b877074f4ffd347baba29411 448 PANTHER PTHR24423 85 121 2.4E-72 T 22-04-2016 HRM2_RS11035 98ae44d5b877074f4ffd347baba29411 448 PANTHER PTHR24423 158 445 2.4E-72 T 22-04-2016 HRM2_RS11035 98ae44d5b877074f4ffd347baba29411 448 Gene3D G3DSA:1.10.287.130 208 272 4.1E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS11035 98ae44d5b877074f4ffd347baba29411 448 Pfam PF00672 HAMP domain 145 212 2.7E-15 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS11035 98ae44d5b877074f4ffd347baba29411 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 441 2.4E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS11035 98ae44d5b877074f4ffd347baba29411 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 422 2.4E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS11035 98ae44d5b877074f4ffd347baba29411 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 398 2.4E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS11035 98ae44d5b877074f4ffd347baba29411 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 384 2.4E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS04940 9fa5933c0bdb6a20257fc175b3af1031 217 PANTHER PTHR30055 16 212 7.1E-38 T 22-04-2016 HRM2_RS04940 9fa5933c0bdb6a20257fc175b3af1031 217 Gene3D G3DSA:1.10.357.10 77 215 1.9E-11 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HRM2_RS04940 9fa5933c0bdb6a20257fc175b3af1031 217 SUPERFAMILY SSF46689 28 98 2.84E-17 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS04940 9fa5933c0bdb6a20257fc175b3af1031 217 Gene3D G3DSA:1.10.10.60 28 76 1.4E-19 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS04940 9fa5933c0bdb6a20257fc175b3af1031 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 46 9.1E-8 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS04940 9fa5933c0bdb6a20257fc175b3af1031 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 54 77 9.1E-8 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS04940 9fa5933c0bdb6a20257fc175b3af1031 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 76 6.9E-14 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS04940 9fa5933c0bdb6a20257fc175b3af1031 217 PANTHER PTHR30055:SF41 16 212 7.1E-38 T 22-04-2016 HRM2_RS10705 a60448d5dd054cc9aaaccfc68aa85a12 629 PANTHER PTHR21432:SF18 1 456 6.3E-141 T 22-04-2016 HRM2_RS10705 a60448d5dd054cc9aaaccfc68aa85a12 629 Pfam PF00583 Acetyltransferase (GNAT) family 531 600 4.1E-7 T 22-04-2016 IPR000182 GNAT domain GO:0008080 HRM2_RS10705 a60448d5dd054cc9aaaccfc68aa85a12 629 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 279 431 1.1E-57 T 22-04-2016 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain HRM2_RS10705 a60448d5dd054cc9aaaccfc68aa85a12 629 Gene3D G3DSA:3.40.630.30 466 607 2.2E-11 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS10705 a60448d5dd054cc9aaaccfc68aa85a12 629 Gene3D G3DSA:3.40.810.20 199 433 8.4E-35 T 22-04-2016 HRM2_RS10705 a60448d5dd054cc9aaaccfc68aa85a12 629 SUPERFAMILY SSF100950 203 437 1.5E-52 T 22-04-2016 HRM2_RS10705 a60448d5dd054cc9aaaccfc68aa85a12 629 SUPERFAMILY SSF55729 468 609 4.71E-15 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS10705 a60448d5dd054cc9aaaccfc68aa85a12 629 PANTHER PTHR21432 1 456 6.3E-141 T 22-04-2016 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 HRM2_RS10705 a60448d5dd054cc9aaaccfc68aa85a12 629 SUPERFAMILY SSF100950 7 229 8.37E-31 T 22-04-2016 HRM2_RS10705 a60448d5dd054cc9aaaccfc68aa85a12 629 Gene3D G3DSA:3.40.1080.10 11 190 1.7E-52 T 22-04-2016 HRM2_RS10705 a60448d5dd054cc9aaaccfc68aa85a12 629 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 23 193 2.5E-24 T 22-04-2016 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 HRM2_RS04165 608f78c1a9de309bd66b390f11bdab67 457 Pfam PF01565 FAD binding domain 40 178 1.4E-43 T 22-04-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 HRM2_RS04165 608f78c1a9de309bd66b390f11bdab67 457 PANTHER PTHR11748 1 455 4.4E-154 T 22-04-2016 HRM2_RS04165 608f78c1a9de309bd66b390f11bdab67 457 SUPERFAMILY SSF55103 219 457 1.64E-67 T 22-04-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 HRM2_RS04165 608f78c1a9de309bd66b390f11bdab67 457 Pfam PF02913 FAD linked oxidases, C-terminal domain 216 455 6.9E-69 T 22-04-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 HRM2_RS04165 608f78c1a9de309bd66b390f11bdab67 457 PANTHER PTHR11748:SF35 1 455 4.4E-154 T 22-04-2016 HRM2_RS04165 608f78c1a9de309bd66b390f11bdab67 457 Gene3D G3DSA:1.10.45.10 417 456 6.4E-12 T 22-04-2016 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 HRM2_RS04165 608f78c1a9de309bd66b390f11bdab67 457 Gene3D G3DSA:3.30.43.10 3 95 1.2E-24 T 22-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 HRM2_RS04165 608f78c1a9de309bd66b390f11bdab67 457 Gene3D G3DSA:3.30.465.10 96 216 3.1E-42 T 22-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 HRM2_RS04165 608f78c1a9de309bd66b390f11bdab67 457 SUPERFAMILY SSF56176 4 216 4.36E-71 T 22-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 HRM2_RS07585 2072bb37058090515e26d64926aa07e8 602 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 284 456 4.0E-23 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS07585 2072bb37058090515e26d64926aa07e8 602 SUPERFAMILY SSF47203 289 475 5.48E-45 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS07585 2072bb37058090515e26d64926aa07e8 602 PANTHER PTHR10909 1 478 4.1E-131 T 22-04-2016 HRM2_RS07585 2072bb37058090515e26d64926aa07e8 602 Gene3D G3DSA:2.40.110.10 161 265 6.7E-25 T 22-04-2016 HRM2_RS07585 2072bb37058090515e26d64926aa07e8 602 SUPERFAMILY SSF56645 39 269 2.09E-44 T 22-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 HRM2_RS07585 2072bb37058090515e26d64926aa07e8 602 Gene3D G3DSA:1.10.540.10 39 155 6.5E-10 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS07585 2072bb37058090515e26d64926aa07e8 602 PANTHER PTHR10909:SF296 1 478 4.1E-131 T 22-04-2016 HRM2_RS07585 2072bb37058090515e26d64926aa07e8 602 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 470 596 2.7E-27 T 22-04-2016 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain HRM2_RS07585 2072bb37058090515e26d64926aa07e8 602 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 269 3.2E-17 T 22-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 HRM2_RS07585 2072bb37058090515e26d64926aa07e8 602 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 4 34 3.9E-7 T 22-04-2016 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria HRM2_RS07585 2072bb37058090515e26d64926aa07e8 602 Gene3D G3DSA:1.20.140.10 266 462 3.6E-50 T 22-04-2016 HRM2_RS07585 2072bb37058090515e26d64926aa07e8 602 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 40 153 8.7E-6 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS24865 4db3ed17a71447cebac45ba5b78f37e0 646 SUPERFAMILY SSF158472 381 427 5.36E-5 T 22-04-2016 HRM2_RS24865 4db3ed17a71447cebac45ba5b78f37e0 646 SUPERFAMILY SSF55073 475 634 3.69E-47 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS24865 4db3ed17a71447cebac45ba5b78f37e0 646 PANTHER PTHR10799:SF750 324 631 1.5E-24 T 22-04-2016 HRM2_RS24865 4db3ed17a71447cebac45ba5b78f37e0 646 PANTHER PTHR10799:SF750 47 60 1.5E-24 T 22-04-2016 HRM2_RS24865 4db3ed17a71447cebac45ba5b78f37e0 646 SMART SM00267 459 634 2.8E-62 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS24865 4db3ed17a71447cebac45ba5b78f37e0 646 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 467 632 2.5E-51 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS24865 4db3ed17a71447cebac45ba5b78f37e0 646 SMART SM00304 381 433 1.9E-5 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS24865 4db3ed17a71447cebac45ba5b78f37e0 646 Pfam PF00990 Diguanylate cyclase, GGDEF domain 471 630 4.3E-48 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS24865 4db3ed17a71447cebac45ba5b78f37e0 646 PANTHER PTHR10799 324 631 1.5E-24 T 22-04-2016 HRM2_RS24865 4db3ed17a71447cebac45ba5b78f37e0 646 PANTHER PTHR10799 47 60 1.5E-24 T 22-04-2016 HRM2_RS24865 4db3ed17a71447cebac45ba5b78f37e0 646 Pfam PF12729 Four helix bundle sensory module for signal transduction 34 169 1.8E-6 T 22-04-2016 IPR024478 4HB MCP domain HRM2_RS24865 4db3ed17a71447cebac45ba5b78f37e0 646 Gene3D G3DSA:3.30.70.270 472 634 4.7E-51 T 22-04-2016 HRM2_RS24865 4db3ed17a71447cebac45ba5b78f37e0 646 Pfam PF00672 HAMP domain 362 428 2.6E-9 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS07055 e04be8c28112c9a8dbd5f17b1c79eb84 511 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 244 509 5.3E-78 T 22-04-2016 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS07055 e04be8c28112c9a8dbd5f17b1c79eb84 511 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 7 205 6.1E-66 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS07055 e04be8c28112c9a8dbd5f17b1c79eb84 511 Gene3D G3DSA:3.60.9.10 1 208 2.5E-72 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS07055 e04be8c28112c9a8dbd5f17b1c79eb84 511 SMART SM00790 6 207 8.6E-83 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS07055 e04be8c28112c9a8dbd5f17b1c79eb84 511 SUPERFAMILY SSF56228 1 208 7.32E-62 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS07055 e04be8c28112c9a8dbd5f17b1c79eb84 511 PANTHER PTHR30038 1 508 2.5E-118 T 22-04-2016 HRM2_RS07055 e04be8c28112c9a8dbd5f17b1c79eb84 511 PANTHER PTHR30038:SF0 1 508 2.5E-118 T 22-04-2016 HRM2_RS07055 e04be8c28112c9a8dbd5f17b1c79eb84 511 SUPERFAMILY SSF48310 244 509 2.35E-67 T 22-04-2016 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS07055 e04be8c28112c9a8dbd5f17b1c79eb84 511 Gene3D G3DSA:1.10.599.10 306 508 4.7E-52 T 22-04-2016 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 HRM2_RS05905 78f43c2804ecc2e2bcea2cfeff46b00e 233 PANTHER PTHR11935 3 222 9.9E-35 T 22-04-2016 HRM2_RS05905 78f43c2804ecc2e2bcea2cfeff46b00e 233 Pfam PF00753 Metallo-beta-lactamase superfamily 17 77 4.6E-8 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS05905 78f43c2804ecc2e2bcea2cfeff46b00e 233 Gene3D G3DSA:3.60.15.10 10 218 4.5E-50 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS05905 78f43c2804ecc2e2bcea2cfeff46b00e 233 SUPERFAMILY SSF56281 4 215 6.44E-45 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS05905 78f43c2804ecc2e2bcea2cfeff46b00e 233 SMART SM00849 13 156 2.2E-17 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS05905 78f43c2804ecc2e2bcea2cfeff46b00e 233 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 157 215 2.8E-7 T 22-04-2016 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386|UniPathway: UPA00619 HRM2_RS21125 432096c440c27782f14df798ff047ce5 426 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 8 415 2.2E-115 T 22-04-2016 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit HRM2_RS21125 432096c440c27782f14df798ff047ce5 426 PIRSF PIRSF006066 1 426 5.6E-152 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS21125 432096c440c27782f14df798ff047ce5 426 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 16 420 1.5E-130 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS21125 432096c440c27782f14df798ff047ce5 426 PANTHER PTHR33362:SF2 1 424 1.6E-150 T 22-04-2016 HRM2_RS21125 432096c440c27782f14df798ff047ce5 426 PANTHER PTHR33362 1 424 1.6E-150 T 22-04-2016 HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 TIGRFAM TIGR00484 EF-G: translation elongation factor G 3 682 5.3E-200 T 22-04-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 PRINTS PR00315 GTP-binding elongation factor signature 128 137 1.8E-5 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 PRINTS PR00315 GTP-binding elongation factor signature 10 23 1.8E-5 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 PRINTS PR00315 GTP-binding elongation factor signature 92 103 1.8E-5 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 PRINTS PR00315 GTP-binding elongation factor signature 76 86 1.8E-5 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 Pfam PF00679 Elongation factor G C-terminus 593 676 3.3E-30 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 SUPERFAMILY SSF54980 595 683 1.77E-28 T 22-04-2016 IPR009022 Elongation factor G, III-V domain HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 177 2.6E-14 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 Gene3D G3DSA:3.30.70.870 399 472 5.2E-22 T 22-04-2016 HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 SUPERFAMILY SSF54980 398 473 1.44E-16 T 22-04-2016 IPR009022 Elongation factor G, III-V domain HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 SUPERFAMILY SSF50447 261 393 2.94E-27 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 SUPERFAMILY SSF52540 5 276 9.0E-72 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 PANTHER PTHR23115:SF98 1 175 2.8E-257 T 22-04-2016 HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 PANTHER PTHR23115:SF98 296 683 2.8E-257 T 22-04-2016 HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 PANTHER PTHR23115:SF98 249 277 2.8E-257 T 22-04-2016 HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 Pfam PF03764 Elongation factor G, domain IV 471 589 1.3E-43 T 22-04-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 SMART SM00889 472 590 2.7E-66 T 22-04-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 Gene3D G3DSA:3.30.230.10 476 594 5.1E-49 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 Pfam PF14492 Elongation Factor G, domain II 398 468 3.8E-21 T 22-04-2016 IPR009022 Elongation factor G, III-V domain HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 Gene3D G3DSA:3.40.50.300 3 280 8.3E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 Gene3D G3DSA:3.30.70.240 595 682 3.9E-31 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 Gene3D G3DSA:2.40.30.10 298 398 8.1E-27 T 22-04-2016 HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 SMART SM00838 592 679 5.1E-43 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 Pfam PF00009 Elongation factor Tu GTP binding domain 6 276 1.7E-37 T 22-04-2016 HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 PANTHER PTHR23115 1 175 2.8E-257 T 22-04-2016 HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 PANTHER PTHR23115 296 683 2.8E-257 T 22-04-2016 HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 PANTHER PTHR23115 249 277 2.8E-257 T 22-04-2016 HRM2_RS12785 e3c725b9f178d6c5446796b74715857c 689 SUPERFAMILY SSF54211 471 591 2.3E-42 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 19 881 0.0 T 22-04-2016 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 Pfam PF00694 Aconitase C-terminal domain 682 809 4.8E-44 T 22-04-2016 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 SUPERFAMILY SSF53732 4 616 2.49E-212 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 Gene3D G3DSA:3.40.1060.10 248 364 9.7E-36 T 22-04-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 PANTHER PTHR11670 406 641 0.0 T 22-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 PANTHER PTHR11670 4 390 0.0 T 22-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 PANTHER PTHR11670 741 882 0.0 T 22-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 PANTHER PTHR11670 657 702 0.0 T 22-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 Gene3D G3DSA:3.30.499.10 19 247 6.9E-76 T 22-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 ProSitePatterns PS00450 Aconitase family signature 1. 417 433 - T 22-04-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 ProSitePatterns PS01244 Aconitase family signature 2. 483 496 - T 22-04-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 PRINTS PR00415 Aconitase family signature 291 304 8.9E-36 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 PRINTS PR00415 Aconitase family signature 483 496 8.9E-36 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 PRINTS PR00415 Aconitase family signature 168 176 8.9E-36 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 PRINTS PR00415 Aconitase family signature 201 214 8.9E-36 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 PRINTS PR00415 Aconitase family signature 277 290 8.9E-36 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 PRINTS PR00415 Aconitase family signature 215 230 8.9E-36 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 PRINTS PR00415 Aconitase family signature 421 432 8.9E-36 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 PRINTS PR00415 Aconitase family signature 369 383 8.9E-36 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 PRINTS PR00415 Aconitase family signature 144 157 8.9E-36 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 Pfam PF00330 Aconitase family (aconitate hydratase) 67 552 1.0E-175 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 PANTHER PTHR11670:SF1 406 641 0.0 T 22-04-2016 HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 PANTHER PTHR11670:SF1 4 390 0.0 T 22-04-2016 HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 PANTHER PTHR11670:SF1 741 882 0.0 T 22-04-2016 HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 PANTHER PTHR11670:SF1 657 702 0.0 T 22-04-2016 HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 Gene3D G3DSA:3.30.499.10 365 564 1.0E-55 T 22-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 SUPERFAMILY SSF52016 621 881 2.35E-81 T 22-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel HRM2_RS05230 507257e657af31f581c8f2ed9e867f9b 882 Gene3D G3DSA:3.20.19.10 627 880 5.0E-73 T 22-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel HRM2_RS14505 06bd26aed7587c7ebad679c1a0b1066f 251 PANTHER PTHR24220 3 182 4.7E-75 T 22-04-2016 HRM2_RS14505 06bd26aed7587c7ebad679c1a0b1066f 251 PANTHER PTHR24220 198 244 4.7E-75 T 22-04-2016 HRM2_RS14505 06bd26aed7587c7ebad679c1a0b1066f 251 SUPERFAMILY SSF52540 2 242 9.91E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14505 06bd26aed7587c7ebad679c1a0b1066f 251 SMART SM00382 26 224 7.3E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS14505 06bd26aed7587c7ebad679c1a0b1066f 251 Gene3D G3DSA:3.40.50.300 1 236 2.0E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14505 06bd26aed7587c7ebad679c1a0b1066f 251 PANTHER PTHR24220:SF85 3 182 4.7E-75 T 22-04-2016 HRM2_RS14505 06bd26aed7587c7ebad679c1a0b1066f 251 PANTHER PTHR24220:SF85 198 244 4.7E-75 T 22-04-2016 HRM2_RS14505 06bd26aed7587c7ebad679c1a0b1066f 251 Pfam PF00005 ABC transporter 17 158 7.8E-24 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS18270 b1abf6f3abac18123b248a03c13e3968 226 PANTHER PTHR30435 1 220 8.5E-50 T 22-04-2016 HRM2_RS18270 b1abf6f3abac18123b248a03c13e3968 226 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 9 107 6.7E-29 T 22-04-2016 IPR020013 Fagellar hook-basal body protein, FlgE/F/G HRM2_RS18270 b1abf6f3abac18123b248a03c13e3968 226 Pfam PF00460 Flagella basal body rod protein 14 35 1.8E-4 T 22-04-2016 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 HRM2_RS18270 b1abf6f3abac18123b248a03c13e3968 226 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 150 220 1.0E-14 T 22-04-2016 IPR010930 Flagellar basal-body/hook protein, C-terminal domain HRM2_RS18270 b1abf6f3abac18123b248a03c13e3968 226 PANTHER PTHR30435:SF16 1 220 8.5E-50 T 22-04-2016 HRM2_RS18270 b1abf6f3abac18123b248a03c13e3968 226 SUPERFAMILY SSF117143 64 183 1.19E-19 T 22-04-2016 HRM2_RS15280 a339110f546fc5c9dc8b2d36dd39627d 197 Hamap MF_00052_B Ribonuclease HII [rnhB]. 15 194 37.489 T 22-04-2016 IPR022898 Ribonuclease HII GO:0004523 HRM2_RS15280 a339110f546fc5c9dc8b2d36dd39627d 197 Gene3D G3DSA:3.30.420.10 15 155 8.3E-47 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS15280 a339110f546fc5c9dc8b2d36dd39627d 197 PANTHER PTHR10954 4 192 2.1E-77 T 22-04-2016 IPR001352 Ribonuclease HII/HIII GO:0003723|GO:0004523 HRM2_RS15280 a339110f546fc5c9dc8b2d36dd39627d 197 Pfam PF01351 Ribonuclease HII 17 192 1.8E-38 T 22-04-2016 IPR024567 Ribonuclease HII/HIII domain HRM2_RS15280 a339110f546fc5c9dc8b2d36dd39627d 197 SUPERFAMILY SSF53098 4 194 1.67E-70 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS22495 ce5852caffee22fb302eadbebca97bef 356 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 47 278 3.3E-52 T 22-04-2016 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 HRM2_RS22495 ce5852caffee22fb302eadbebca97bef 356 PANTHER PTHR33376 301 355 1.7E-46 T 22-04-2016 HRM2_RS22495 ce5852caffee22fb302eadbebca97bef 356 PANTHER PTHR33376 1 281 1.7E-46 T 22-04-2016 HRM2_RS22495 ce5852caffee22fb302eadbebca97bef 356 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 41 278 6.4E-60 T 22-04-2016 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 HRM2_RS14735 1d004b27fc1d9786997c6261559c0296 475 SUPERFAMILY SSF53448 312 465 4.41E-10 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS14735 1d004b27fc1d9786997c6261559c0296 475 SUPERFAMILY SSF53448 9 217 7.22E-51 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS14735 1d004b27fc1d9786997c6261559c0296 475 Pfam PF00535 Glycosyl transferase family 2 12 141 7.1E-26 T 22-04-2016 IPR001173 Glycosyltransferase 2-like HRM2_RS14735 1d004b27fc1d9786997c6261559c0296 475 PANTHER PTHR22916 5 211 1.8E-43 T 22-04-2016 HRM2_RS14735 1d004b27fc1d9786997c6261559c0296 475 Gene3D G3DSA:3.90.550.10 355 458 1.2E-8 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS14735 1d004b27fc1d9786997c6261559c0296 475 Gene3D G3DSA:3.90.550.10 9 219 1.2E-52 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS13380 d5acf58f20b0bdad17e854803a90eaba 222 Pfam PF00834 Ribulose-phosphate 3 epimerase family 4 200 9.1E-81 T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 HRM2_RS13380 d5acf58f20b0bdad17e854803a90eaba 222 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 133 155 - T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 HRM2_RS13380 d5acf58f20b0bdad17e854803a90eaba 222 PANTHER PTHR11749 1 217 6.4E-116 T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 HRM2_RS13380 d5acf58f20b0bdad17e854803a90eaba 222 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 4 213 2.3E-88 T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 HRM2_RS13380 d5acf58f20b0bdad17e854803a90eaba 222 Gene3D G3DSA:3.20.20.70 1 214 1.5E-90 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS13380 d5acf58f20b0bdad17e854803a90eaba 222 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 HRM2_RS13380 d5acf58f20b0bdad17e854803a90eaba 222 SUPERFAMILY SSF51366 2 214 1.01E-69 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 HRM2_RS13380 d5acf58f20b0bdad17e854803a90eaba 222 PIRSF PIRSF001461 1 221 8.2E-92 T 22-04-2016 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 HRM2_RS07455 d151591a8159b1dec7dc16cb71cb2c87 264 PANTHER PTHR24320 2 233 2.5E-54 T 22-04-2016 HRM2_RS07455 d151591a8159b1dec7dc16cb71cb2c87 264 SUPERFAMILY SSF51735 2 242 6.35E-46 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS07455 d151591a8159b1dec7dc16cb71cb2c87 264 PANTHER PTHR24320:SF89 2 233 2.5E-54 T 22-04-2016 HRM2_RS07455 d151591a8159b1dec7dc16cb71cb2c87 264 Gene3D G3DSA:3.40.50.720 2 239 7.1E-50 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS07455 d151591a8159b1dec7dc16cb71cb2c87 264 Pfam PF00106 short chain dehydrogenase 3 201 1.7E-30 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS07455 d151591a8159b1dec7dc16cb71cb2c87 264 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 22-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 HRM2_RS07455 d151591a8159b1dec7dc16cb71cb2c87 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 3.9E-6 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS07455 d151591a8159b1dec7dc16cb71cb2c87 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 3.9E-6 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS07455 d151591a8159b1dec7dc16cb71cb2c87 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.9E-6 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS07455 d151591a8159b1dec7dc16cb71cb2c87 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 5.5E-14 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS07455 d151591a8159b1dec7dc16cb71cb2c87 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 5.5E-14 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS07455 d151591a8159b1dec7dc16cb71cb2c87 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 5.5E-14 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS07455 d151591a8159b1dec7dc16cb71cb2c87 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 5.5E-14 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS07455 d151591a8159b1dec7dc16cb71cb2c87 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 5.5E-14 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 SUPERFAMILY SSF47336 2901 2995 9.55E-16 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Gene3D G3DSA:3.40.47.10 1000 1160 1.5E-37 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Gene3D G3DSA:3.40.47.10 1484 1623 7.2E-13 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 899 915 - T 22-04-2016 IPR018201 Beta-ketoacyl synthase, active site HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2323 2339 - T 22-04-2016 IPR018201 Beta-ketoacyl synthase, active site HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 SUPERFAMILY SSF53901 882 1104 1.5E-63 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 SUPERFAMILY SSF47336 2689 2776 1.1E-12 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Gene3D G3DSA:3.40.47.10 2493 2590 5.5E-10 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Gene3D G3DSA:3.40.47.10 1178 1473 2.9E-55 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1469 1578 7.0E-7 T 22-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 994 1107 2.0E-28 T 22-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2492 2546 1.7E-4 T 22-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Pfam PF08659 KR domain 3266 3470 6.2E-33 T 22-04-2016 IPR013968 Polyketide synthase, ketoreductase domain HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Gene3D G3DSA:3.40.366.10 1863 1959 8.0E-62 T 22-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Gene3D G3DSA:3.40.366.10 1666 1792 8.0E-62 T 22-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 SUPERFAMILY SSF52151 1672 1798 4.71E-56 T 22-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 SUPERFAMILY SSF52151 1865 1958 4.71E-56 T 22-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 SUPERFAMILY SSF53901 2174 2212 5.77E-29 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 697 985 1.1E-61 T 22-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1181 1460 1.6E-47 T 22-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2311 2416 5.8E-11 T 22-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 SUPERFAMILY SSF55048 1799 1863 1.96E-5 T 22-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 SUPERFAMILY SSF53901 1430 1628 2.21E-25 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 PANTHER PTHR11712:SF234 879 1170 8.9E-195 T 22-04-2016 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 PANTHER PTHR11712:SF234 153 832 8.9E-195 T 22-04-2016 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 PANTHER PTHR11712:SF234 1561 1957 8.9E-195 T 22-04-2016 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Gene3D G3DSA:1.10.1200.10 2688 2759 5.6E-13 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Gene3D G3DSA:1.10.1200.10 2904 2979 1.0E-14 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Gene3D G3DSA:1.10.1200.10 2795 2867 7.6E-14 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Gene3D G3DSA:3.40.50.720 3264 3299 2.0E-33 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Gene3D G3DSA:3.40.50.720 3344 3500 2.0E-33 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 SUPERFAMILY SSF51735 3046 3248 5.61E-6 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Pfam PF00550 Phosphopantetheine attachment site 2692 2759 5.7E-6 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Pfam PF00550 Phosphopantetheine attachment site 2908 2974 2.2E-8 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Pfam PF00550 Phosphopantetheine attachment site 2800 2867 4.7E-7 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 SUPERFAMILY SSF51412 2 221 1.05E-7 T 22-04-2016 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 SUPERFAMILY SSF47336 2794 2877 5.37E-14 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 SUPERFAMILY SSF51412 328 592 1.13E-7 T 22-04-2016 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 SUPERFAMILY SSF53901 2306 2587 5.77E-29 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 SUPERFAMILY SSF53901 1181 1303 8.52E-49 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 SUPERFAMILY SSF53901 1330 1467 8.52E-49 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 SUPERFAMILY SSF53901 696 824 1.5E-63 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Gene3D G3DSA:3.30.70.250 1800 1856 6.8E-4 T 22-04-2016 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 PANTHER PTHR11712 879 1170 8.9E-195 T 22-04-2016 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 PANTHER PTHR11712 153 832 8.9E-195 T 22-04-2016 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 PANTHER PTHR11712 1561 1957 8.9E-195 T 22-04-2016 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Pfam PF00698 Acyl transferase domain 1676 1954 1.1E-39 T 22-04-2016 IPR014043 Acyl transferase HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 SUPERFAMILY SSF51735 3349 3521 5.89E-30 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 SUPERFAMILY SSF51735 3264 3305 5.89E-30 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 SMART SM00825 Beta-ketoacyl synthase 699 1161 5.9E-65 T 22-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Gene3D G3DSA:3.40.47.10 857 997 2.4E-65 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Gene3D G3DSA:3.40.47.10 699 824 2.4E-65 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Gene3D G3DSA:3.40.47.10 2282 2431 4.5E-27 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Gene3D G3DSA:3.40.47.10 2083 2241 4.5E-27 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 Pfam PF14765 Polyketide synthase dehydratase 3550 3843 5.7E-26 T 22-04-2016 IPR020807 Polyketide synthase, dehydratase domain HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1675 1973 1.1E-32 T 22-04-2016 IPR020801 Polyketide synthase, acyl transferase domain HRM2_RS15765 9a68007281dfcd8aaef728ea2830d381 3859 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3266 3485 6.6E-16 T 22-04-2016 HRM2_RS01335 5ee6b0b7c3d2a59fce8f88aec7a24bec 568 PANTHER PTHR11059 2 562 3.3E-149 T 22-04-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 HRM2_RS01335 5ee6b0b7c3d2a59fce8f88aec7a24bec 568 Gene3D G3DSA:3.40.50.300 1 206 5.9E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01335 5ee6b0b7c3d2a59fce8f88aec7a24bec 568 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 563 2.0E-159 T 22-04-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 HRM2_RS01335 5ee6b0b7c3d2a59fce8f88aec7a24bec 568 Gene3D G3DSA:3.40.50.300 441 510 8.7E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01335 5ee6b0b7c3d2a59fce8f88aec7a24bec 568 SUPERFAMILY SSF52540 1 199 6.59E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01335 5ee6b0b7c3d2a59fce8f88aec7a24bec 568 SUPERFAMILY SSF52540 314 522 6.59E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01335 5ee6b0b7c3d2a59fce8f88aec7a24bec 568 PIRSF PIRSF003128 1 566 4.0E-170 T 22-04-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 HRM2_RS01335 5ee6b0b7c3d2a59fce8f88aec7a24bec 568 Pfam PF02463 RecF/RecN/SMC N terminal domain 1 517 1.7E-18 T 22-04-2016 IPR003395 RecF/RecN/SMC, N-terminal HRM2_RS01900 a7a49d2f83a7e8f146de83e544f9061f 978 SUPERFAMILY SSF52540 455 476 1.06E-21 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01900 a7a49d2f83a7e8f146de83e544f9061f 978 SUPERFAMILY SSF52540 580 608 1.06E-21 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01900 a7a49d2f83a7e8f146de83e544f9061f 978 SUPERFAMILY SSF52540 670 820 1.06E-21 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01900 a7a49d2f83a7e8f146de83e544f9061f 978 Pfam PF04851 Type III restriction enzyme, res subunit 454 612 6.8E-19 T 22-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HRM2_RS01900 a7a49d2f83a7e8f146de83e544f9061f 978 SUPERFAMILY SSF52540 366 628 6.59E-34 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01900 a7a49d2f83a7e8f146de83e544f9061f 978 Gene3D G3DSA:3.40.50.300 450 625 8.4E-29 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01900 a7a49d2f83a7e8f146de83e544f9061f 978 Gene3D G3DSA:3.30.870.10 841 973 2.4E-11 T 22-04-2016 HRM2_RS01900 a7a49d2f83a7e8f146de83e544f9061f 978 Pfam PF13091 PLD-like domain 854 965 3.5E-10 T 22-04-2016 IPR025202 Phospholipase D-like domain HRM2_RS01900 a7a49d2f83a7e8f146de83e544f9061f 978 PANTHER PTHR11274 447 521 1.2E-25 T 22-04-2016 HRM2_RS01900 a7a49d2f83a7e8f146de83e544f9061f 978 PANTHER PTHR11274 537 629 1.2E-25 T 22-04-2016 HRM2_RS01900 a7a49d2f83a7e8f146de83e544f9061f 978 SMART SM00487 451 645 1.9E-16 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS01900 a7a49d2f83a7e8f146de83e544f9061f 978 SUPERFAMILY SSF56024 838 973 4.08E-13 T 22-04-2016 HRM2_RS01900 a7a49d2f83a7e8f146de83e544f9061f 978 Gene3D G3DSA:3.40.50.300 666 818 4.2E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02485 3aeb49a6f4e558579ad9235f341f0741 620 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 271 421 4.2E-39 T 22-04-2016 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain HRM2_RS02485 3aeb49a6f4e558579ad9235f341f0741 620 SUPERFAMILY SSF100950 5 216 2.66E-31 T 22-04-2016 HRM2_RS02485 3aeb49a6f4e558579ad9235f341f0741 620 Gene3D G3DSA:3.40.630.30 458 593 5.8E-16 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS02485 3aeb49a6f4e558579ad9235f341f0741 620 Gene3D G3DSA:3.30.750.70 186 287 2.0E-21 T 22-04-2016 HRM2_RS02485 3aeb49a6f4e558579ad9235f341f0741 620 PANTHER PTHR21432 6 434 1.7E-100 T 22-04-2016 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 HRM2_RS02485 3aeb49a6f4e558579ad9235f341f0741 620 SUPERFAMILY SSF100950 186 432 3.73E-35 T 22-04-2016 HRM2_RS02485 3aeb49a6f4e558579ad9235f341f0741 620 PANTHER PTHR21432:SF18 6 434 1.7E-100 T 22-04-2016 HRM2_RS02485 3aeb49a6f4e558579ad9235f341f0741 620 SUPERFAMILY SSF55729 457 601 1.28E-16 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS02485 3aeb49a6f4e558579ad9235f341f0741 620 Pfam PF00583 Acetyltransferase (GNAT) family 524 593 5.2E-7 T 22-04-2016 IPR000182 GNAT domain GO:0008080 HRM2_RS02485 3aeb49a6f4e558579ad9235f341f0741 620 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 3 179 2.2E-13 T 22-04-2016 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 HRM2_RS02485 3aeb49a6f4e558579ad9235f341f0741 620 Gene3D G3DSA:3.40.1080.10 5 182 1.6E-49 T 22-04-2016 HRM2_RS06730 04b44b01af7285d25c40349c4bcb6f94 321 PANTHER PTHR10584 1 316 3.7E-107 T 22-04-2016 HRM2_RS06730 04b44b01af7285d25c40349c4bcb6f94 321 Gene3D G3DSA:3.40.1190.20 13 320 4.5E-58 T 22-04-2016 IPR029056 Ribokinase-like HRM2_RS06730 04b44b01af7285d25c40349c4bcb6f94 321 SUPERFAMILY SSF53613 13 318 5.06E-52 T 22-04-2016 IPR029056 Ribokinase-like HRM2_RS06730 04b44b01af7285d25c40349c4bcb6f94 321 PANTHER PTHR10584:SF159 1 316 3.7E-107 T 22-04-2016 HRM2_RS06730 04b44b01af7285d25c40349c4bcb6f94 321 Pfam PF00294 pfkB family carbohydrate kinase 14 311 2.1E-39 T 22-04-2016 IPR011611 Carbohydrate kinase PfkB HRM2_RS06730 04b44b01af7285d25c40349c4bcb6f94 321 TIGRFAM TIGR02198 rfaE_dom_I: bifunctional protein RfaE, domain I 5 318 3.4E-108 T 22-04-2016 IPR011913 RfaE bifunctional protein, domain I GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167|UniPathway: UPA00356|UniPathway: UPA00356 HRM2_RS05645 e048fb0ed4781db0630e521f6e96d6ea 366 Pfam PF00226 DnaJ domain 6 68 6.4E-26 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS05645 e048fb0ed4781db0630e521f6e96d6ea 366 PANTHER PTHR24078 1 347 1.4E-145 T 22-04-2016 HRM2_RS05645 e048fb0ed4781db0630e521f6e96d6ea 366 Gene3D G3DSA:2.10.230.10 141 209 8.7E-22 T 22-04-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 HRM2_RS05645 e048fb0ed4781db0630e521f6e96d6ea 366 PRINTS PR00625 DnaJ domain signature 43 63 2.1E-29 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS05645 e048fb0ed4781db0630e521f6e96d6ea 366 PRINTS PR00625 DnaJ domain signature 26 41 2.1E-29 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS05645 e048fb0ed4781db0630e521f6e96d6ea 366 PRINTS PR00625 DnaJ domain signature 8 26 2.1E-29 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS05645 e048fb0ed4781db0630e521f6e96d6ea 366 PRINTS PR00625 DnaJ domain signature 63 82 2.1E-29 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS05645 e048fb0ed4781db0630e521f6e96d6ea 366 SUPERFAMILY SSF57938 134 209 5.89E-20 T 22-04-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 HRM2_RS05645 e048fb0ed4781db0630e521f6e96d6ea 366 Gene3D G3DSA:2.60.260.20 108 140 1.4E-17 T 22-04-2016 HRM2_RS05645 e048fb0ed4781db0630e521f6e96d6ea 366 Gene3D G3DSA:2.60.260.20 210 254 1.4E-17 T 22-04-2016 HRM2_RS05645 e048fb0ed4781db0630e521f6e96d6ea 366 Gene3D G3DSA:2.60.260.20 256 334 1.2E-19 T 22-04-2016 HRM2_RS05645 e048fb0ed4781db0630e521f6e96d6ea 366 Pfam PF00684 DnaJ central domain 147 207 6.6E-12 T 22-04-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 HRM2_RS05645 e048fb0ed4781db0630e521f6e96d6ea 366 SUPERFAMILY SSF49493 186 267 2.22E-20 T 22-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 HRM2_RS05645 e048fb0ed4781db0630e521f6e96d6ea 366 SUPERFAMILY SSF49493 114 138 2.22E-20 T 22-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 HRM2_RS05645 e048fb0ed4781db0630e521f6e96d6ea 366 Gene3D G3DSA:1.10.287.110 1 105 8.7E-34 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS05645 e048fb0ed4781db0630e521f6e96d6ea 366 SUPERFAMILY SSF46565 2 106 2.36E-33 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS05645 e048fb0ed4781db0630e521f6e96d6ea 366 SUPERFAMILY SSF49493 259 344 1.44E-20 T 22-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 HRM2_RS05645 e048fb0ed4781db0630e521f6e96d6ea 366 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 6 348 2.2E-130 T 22-04-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 HRM2_RS05645 e048fb0ed4781db0630e521f6e96d6ea 366 PANTHER PTHR24078:SF190 1 347 1.4E-145 T 22-04-2016 HRM2_RS05645 e048fb0ed4781db0630e521f6e96d6ea 366 SMART SM00271 5 63 5.4E-28 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS05645 e048fb0ed4781db0630e521f6e96d6ea 366 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 3 362 39.05 T 22-04-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 HRM2_RS05645 e048fb0ed4781db0630e521f6e96d6ea 366 Pfam PF01556 DnaJ C terminal domain 121 333 5.4E-40 T 22-04-2016 IPR002939 Chaperone DnaJ, C-terminal HRM2_RS16875 47722751e9dd389c221092dcc4293737 613 SUPERFAMILY SSF51905 39 261 2.98E-39 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS16875 47722751e9dd389c221092dcc4293737 613 SUPERFAMILY SSF51905 380 436 2.98E-39 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS16875 47722751e9dd389c221092dcc4293737 613 Pfam PF02910 Fumarate reductase flavoprotein C-term 470 572 9.3E-14 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 HRM2_RS16875 47722751e9dd389c221092dcc4293737 613 PANTHER PTHR11632 391 570 2.7E-24 T 22-04-2016 HRM2_RS16875 47722751e9dd389c221092dcc4293737 613 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 203 221 2.03E-8 T 22-04-2016 HRM2_RS16875 47722751e9dd389c221092dcc4293737 613 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 51 70 2.03E-8 T 22-04-2016 HRM2_RS16875 47722751e9dd389c221092dcc4293737 613 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 379 401 2.03E-8 T 22-04-2016 HRM2_RS16875 47722751e9dd389c221092dcc4293737 613 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 50 72 2.91E-7 T 22-04-2016 HRM2_RS16875 47722751e9dd389c221092dcc4293737 613 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 206 215 2.91E-7 T 22-04-2016 HRM2_RS16875 47722751e9dd389c221092dcc4293737 613 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 394 401 2.91E-7 T 22-04-2016 HRM2_RS16875 47722751e9dd389c221092dcc4293737 613 Gene3D G3DSA:1.20.58.100 466 568 5.5E-24 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 HRM2_RS16875 47722751e9dd389c221092dcc4293737 613 Pfam PF00890 FAD binding domain 50 150 9.5E-7 T 22-04-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain HRM2_RS16875 47722751e9dd389c221092dcc4293737 613 SUPERFAMILY SSF46977 459 583 1.23E-27 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 HRM2_RS16875 47722751e9dd389c221092dcc4293737 613 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 8 36 1.5E-5 T 22-04-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal HRM2_RS16875 47722751e9dd389c221092dcc4293737 613 Gene3D G3DSA:3.50.50.60 379 465 1.1E-44 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS16875 47722751e9dd389c221092dcc4293737 613 Gene3D G3DSA:3.50.50.60 43 273 1.1E-44 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS12280 aba5f7240067da57702f89254aa03dd3 565 Gene3D G3DSA:3.90.550.10 1 227 2.3E-51 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS12280 aba5f7240067da57702f89254aa03dd3 565 Gene3D G3DSA:3.30.200.20 246 323 8.5E-11 T 22-04-2016 HRM2_RS12280 aba5f7240067da57702f89254aa03dd3 565 Pfam PF00483 Nucleotidyl transferase 2 227 1.2E-22 T 22-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 HRM2_RS12280 aba5f7240067da57702f89254aa03dd3 565 PANTHER PTHR22572 2 227 2.5E-45 T 22-04-2016 HRM2_RS12280 aba5f7240067da57702f89254aa03dd3 565 SUPERFAMILY SSF56112 244 541 6.81E-27 T 22-04-2016 IPR011009 Protein kinase-like domain HRM2_RS12280 aba5f7240067da57702f89254aa03dd3 565 Gene3D G3DSA:3.90.1200.10 328 556 1.0E-31 T 22-04-2016 HRM2_RS12280 aba5f7240067da57702f89254aa03dd3 565 Pfam PF01636 Phosphotransferase enzyme family 251 465 3.7E-10 T 22-04-2016 IPR002575 Aminoglycoside phosphotransferase HRM2_RS12280 aba5f7240067da57702f89254aa03dd3 565 SUPERFAMILY SSF53448 1 231 1.44E-51 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS12115 987956d7b3d2af3cb53826c857fe6daf 747 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 3 55 6.0E-11 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS12115 987956d7b3d2af3cb53826c857fe6daf 747 Gene3D G3DSA:2.40.40.20 616 744 1.5E-19 T 22-04-2016 HRM2_RS12115 987956d7b3d2af3cb53826c857fe6daf 747 Gene3D G3DSA:3.40.50.740 316 489 6.1E-50 T 22-04-2016 HRM2_RS12115 987956d7b3d2af3cb53826c857fe6daf 747 Gene3D G3DSA:3.40.50.740 60 131 6.1E-50 T 22-04-2016 HRM2_RS12115 987956d7b3d2af3cb53826c857fe6daf 747 Gene3D G3DSA:2.20.25.90 2 59 1.7E-14 T 22-04-2016 HRM2_RS12115 987956d7b3d2af3cb53826c857fe6daf 747 Pfam PF01568 Molydopterin dinucleotide binding domain 628 731 1.3E-15 T 22-04-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 HRM2_RS12115 987956d7b3d2af3cb53826c857fe6daf 747 Pfam PF00384 Molybdopterin oxidoreductase 59 471 6.5E-34 T 22-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 HRM2_RS12115 987956d7b3d2af3cb53826c857fe6daf 747 SMART SM00926 2 56 7.6E-11 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS12115 987956d7b3d2af3cb53826c857fe6daf 747 SUPERFAMILY SSF53706 3 630 3.14E-115 T 22-04-2016 HRM2_RS12115 987956d7b3d2af3cb53826c857fe6daf 747 PANTHER PTHR11615:SF110 1 499 2.0E-105 T 22-04-2016 HRM2_RS12115 987956d7b3d2af3cb53826c857fe6daf 747 PANTHER PTHR11615:SF110 542 747 2.0E-105 T 22-04-2016 HRM2_RS12115 987956d7b3d2af3cb53826c857fe6daf 747 Gene3D G3DSA:3.40.228.10 144 315 3.1E-35 T 22-04-2016 HRM2_RS12115 987956d7b3d2af3cb53826c857fe6daf 747 SUPERFAMILY SSF50692 622 746 2.01E-23 T 22-04-2016 IPR009010 Aspartate decarboxylase-like domain HRM2_RS12115 987956d7b3d2af3cb53826c857fe6daf 747 PANTHER PTHR11615 1 499 2.0E-105 T 22-04-2016 HRM2_RS12115 987956d7b3d2af3cb53826c857fe6daf 747 PANTHER PTHR11615 542 747 2.0E-105 T 22-04-2016 HRM2_RS24330 d6375f017fbf90a1cce8e22dcae8c45c 517 Gene3D G3DSA:3.40.190.10 124 286 1.1E-42 T 22-04-2016 HRM2_RS24330 d6375f017fbf90a1cce8e22dcae8c45c 517 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 67 424 4.2E-85 T 22-04-2016 IPR000914 Solute-binding protein family 5 domain HRM2_RS24330 d6375f017fbf90a1cce8e22dcae8c45c 517 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 72 93 - T 22-04-2016 IPR023765 Solute-binding protein family 5, conserved site HRM2_RS24330 d6375f017fbf90a1cce8e22dcae8c45c 517 Gene3D G3DSA:3.10.105.10 287 485 3.9E-53 T 22-04-2016 HRM2_RS24330 d6375f017fbf90a1cce8e22dcae8c45c 517 SUPERFAMILY SSF53850 23 516 1.3E-127 T 22-04-2016 HRM2_RS24330 d6375f017fbf90a1cce8e22dcae8c45c 517 PANTHER PTHR30290:SF24 25 511 1.3E-156 T 22-04-2016 HRM2_RS24330 d6375f017fbf90a1cce8e22dcae8c45c 517 PANTHER PTHR30290 25 511 1.3E-156 T 22-04-2016 HRM2_RS24330 d6375f017fbf90a1cce8e22dcae8c45c 517 PIRSF PIRSF002741 18 503 9.9E-86 T 22-04-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 HRM2_RS14135 8a82f298548583e39788c64e08a005bd 335 Pfam PF00005 ABC transporter 37 186 4.9E-30 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS14135 8a82f298548583e39788c64e08a005bd 335 SUPERFAMILY SSF52540 10 258 8.99E-74 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14135 8a82f298548583e39788c64e08a005bd 335 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS14135 8a82f298548583e39788c64e08a005bd 335 Gene3D G3DSA:3.40.50.300 8 260 1.5E-81 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14135 8a82f298548583e39788c64e08a005bd 335 PANTHER PTHR24220 11 330 7.7E-156 T 22-04-2016 HRM2_RS14135 8a82f298548583e39788c64e08a005bd 335 PANTHER PTHR24220:SF336 11 330 7.7E-156 T 22-04-2016 HRM2_RS14135 8a82f298548583e39788c64e08a005bd 335 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 303 1.2E-18 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HRM2_RS14135 8a82f298548583e39788c64e08a005bd 335 SMART SM00382 45 236 1.2E-17 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS14135 8a82f298548583e39788c64e08a005bd 335 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 236 326 9.6E-26 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HRM2_RS00175 43689da67a33b012be84f547b0fe08a7 558 SUPERFAMILY SSF81901 251 528 3.4E-42 T 22-04-2016 HRM2_RS00175 43689da67a33b012be84f547b0fe08a7 558 PANTHER PTHR19959:SF118 161 548 9.1E-132 T 22-04-2016 HRM2_RS00175 43689da67a33b012be84f547b0fe08a7 558 PANTHER PTHR19959:SF118 86 99 9.1E-132 T 22-04-2016 HRM2_RS00175 43689da67a33b012be84f547b0fe08a7 558 Gene3D G3DSA:1.25.40.10 131 430 4.2E-64 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS00175 43689da67a33b012be84f547b0fe08a7 558 Pfam PF08238 Sel1 repeat 175 198 47.0 T 22-04-2016 IPR006597 Sel1-like repeat HRM2_RS00175 43689da67a33b012be84f547b0fe08a7 558 Gene3D G3DSA:1.10.150.160 431 468 9.6E-6 T 22-04-2016 IPR023114 Elongated TPR repeat-containing domain HRM2_RS00175 43689da67a33b012be84f547b0fe08a7 558 SUPERFAMILY SSF48452 168 278 5.96E-21 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS00175 43689da67a33b012be84f547b0fe08a7 558 SMART SM00028 248 281 4.0E-4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS00175 43689da67a33b012be84f547b0fe08a7 558 SMART SM00028 172 205 0.61 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS00175 43689da67a33b012be84f547b0fe08a7 558 SMART SM00028 332 365 0.0064 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS00175 43689da67a33b012be84f547b0fe08a7 558 SMART SM00028 290 323 0.0013 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS00175 43689da67a33b012be84f547b0fe08a7 558 SMART SM00028 206 239 0.21 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS00175 43689da67a33b012be84f547b0fe08a7 558 SMART SM00028 374 407 2.3E-4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS00175 43689da67a33b012be84f547b0fe08a7 558 SMART SM00028 416 449 7.8E-5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS00175 43689da67a33b012be84f547b0fe08a7 558 SMART SM00028 458 491 1.5E-6 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS00175 43689da67a33b012be84f547b0fe08a7 558 SMART SM00028 500 533 8.7E-5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS00175 43689da67a33b012be84f547b0fe08a7 558 Pfam PF13424 Tetratricopeptide repeat 293 360 6.9E-13 T 22-04-2016 HRM2_RS00175 43689da67a33b012be84f547b0fe08a7 558 Pfam PF13424 Tetratricopeptide repeat 373 445 1.8E-18 T 22-04-2016 HRM2_RS00175 43689da67a33b012be84f547b0fe08a7 558 Pfam PF13424 Tetratricopeptide repeat 209 277 2.2E-13 T 22-04-2016 HRM2_RS00175 43689da67a33b012be84f547b0fe08a7 558 Pfam PF13424 Tetratricopeptide repeat 456 532 1.4E-16 T 22-04-2016 HRM2_RS00175 43689da67a33b012be84f547b0fe08a7 558 Gene3D G3DSA:1.25.40.10 469 534 1.2E-16 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS00175 43689da67a33b012be84f547b0fe08a7 558 PRINTS PR00381 Kinesin light chain signature 491 512 3.8E-9 T 22-04-2016 IPR002151 Kinesin light chain GO:0003777|GO:0005871 HRM2_RS00175 43689da67a33b012be84f547b0fe08a7 558 PRINTS PR00381 Kinesin light chain signature 347 365 3.8E-9 T 22-04-2016 IPR002151 Kinesin light chain GO:0003777|GO:0005871 HRM2_RS00175 43689da67a33b012be84f547b0fe08a7 558 PRINTS PR00381 Kinesin light chain signature 412 429 3.8E-9 T 22-04-2016 IPR002151 Kinesin light chain GO:0003777|GO:0005871 HRM2_RS00175 43689da67a33b012be84f547b0fe08a7 558 PRINTS PR00381 Kinesin light chain signature 456 476 3.8E-9 T 22-04-2016 IPR002151 Kinesin light chain GO:0003777|GO:0005871 HRM2_RS00175 43689da67a33b012be84f547b0fe08a7 558 PANTHER PTHR19959 161 548 9.1E-132 T 22-04-2016 HRM2_RS00175 43689da67a33b012be84f547b0fe08a7 558 PANTHER PTHR19959 86 99 9.1E-132 T 22-04-2016 HRM2_RS22305 b7bfdf4cca192ec7aca95525d8cf6cca 159 PANTHER PTHR11717:SF18 1 158 2.9E-39 T 22-04-2016 HRM2_RS22305 b7bfdf4cca192ec7aca95525d8cf6cca 159 SMART SM00226 5 145 1.5E-37 T 22-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily HRM2_RS22305 b7bfdf4cca192ec7aca95525d8cf6cca 159 SUPERFAMILY SSF52788 5 142 2.22E-40 T 22-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily HRM2_RS22305 b7bfdf4cca192ec7aca95525d8cf6cca 159 PANTHER PTHR11717 1 158 2.9E-39 T 22-04-2016 HRM2_RS22305 b7bfdf4cca192ec7aca95525d8cf6cca 159 Gene3D G3DSA:3.40.50.270 3 142 2.8E-45 T 22-04-2016 HRM2_RS22305 b7bfdf4cca192ec7aca95525d8cf6cca 159 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 103 4.0E-20 T 22-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily HRM2_RS00575 09442e9a672e648f3419f5966ec49ecf 559 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 466 477 - T 22-04-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HRM2_RS00575 09442e9a672e648f3419f5966ec49ecf 559 SUPERFAMILY SSF143975 3 379 2.22E-137 T 22-04-2016 HRM2_RS00575 09442e9a672e648f3419f5966ec49ecf 559 Pfam PF00920 Dehydratase family 37 555 6.6E-219 T 22-04-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HRM2_RS00575 09442e9a672e648f3419f5966ec49ecf 559 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 125 135 - T 22-04-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HRM2_RS00575 09442e9a672e648f3419f5966ec49ecf 559 PANTHER PTHR21000:SF5 2 559 0.0 T 22-04-2016 HRM2_RS00575 09442e9a672e648f3419f5966ec49ecf 559 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 7 558 42.727 T 22-04-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HRM2_RS00575 09442e9a672e648f3419f5966ec49ecf 559 SUPERFAMILY SSF52016 381 558 1.57E-56 T 22-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel HRM2_RS00575 09442e9a672e648f3419f5966ec49ecf 559 PANTHER PTHR21000 2 559 0.0 T 22-04-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HRM2_RS00575 09442e9a672e648f3419f5966ec49ecf 559 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 21 558 2.4E-228 T 22-04-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HRM2_RS15570 47bbaaba7f200adbd1fb68c378562c89 95 SUPERFAMILY SSF141000 2 93 2.88E-24 T 22-04-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 HRM2_RS15570 47bbaaba7f200adbd1fb68c378562c89 95 PANTHER PTHR15004:SF0 1 95 3.6E-23 T 22-04-2016 HRM2_RS15570 47bbaaba7f200adbd1fb68c378562c89 95 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 22 90 3.2E-14 T 22-04-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 HRM2_RS15570 47bbaaba7f200adbd1fb68c378562c89 95 PANTHER PTHR15004 1 95 3.6E-23 T 22-04-2016 HRM2_RS15570 47bbaaba7f200adbd1fb68c378562c89 95 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 3 94 2.9E-21 T 22-04-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 HRM2_RS15570 47bbaaba7f200adbd1fb68c378562c89 95 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 95 20.349 T 22-04-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 HRM2_RS23835 029389ff1537eddf09dff53f91a977dd 425 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 18 420 6.0E-118 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS23835 029389ff1537eddf09dff53f91a977dd 425 PANTHER PTHR33362 1 425 3.6E-126 T 22-04-2016 HRM2_RS23835 029389ff1537eddf09dff53f91a977dd 425 PANTHER PTHR33362:SF2 1 425 3.6E-126 T 22-04-2016 HRM2_RS23835 029389ff1537eddf09dff53f91a977dd 425 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 8 415 2.3E-108 T 22-04-2016 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit HRM2_RS23835 029389ff1537eddf09dff53f91a977dd 425 PIRSF PIRSF006066 1 425 1.0E-144 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS09470 a67081265928a42f142feb2006aa263f 591 SUPERFAMILY SSF47831 38 152 7.32E-26 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 HRM2_RS09470 a67081265928a42f142feb2006aa263f 591 SUPERFAMILY SSF52009 135 255 2.35E-32 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS09470 a67081265928a42f142feb2006aa263f 591 Gene3D G3DSA:3.50.30.10 142 263 1.4E-36 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS09470 a67081265928a42f142feb2006aa263f 591 Gene3D G3DSA:1.10.274.10 37 141 8.3E-28 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 HRM2_RS09470 a67081265928a42f142feb2006aa263f 591 Pfam PF05524 PEP-utilising enzyme, N-terminal 13 135 2.1E-25 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 HRM2_RS09470 a67081265928a42f142feb2006aa263f 591 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 261 550 3.7E-108 T 22-04-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 HRM2_RS09470 a67081265928a42f142feb2006aa263f 591 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 473 488 2.2E-26 T 22-04-2016 HRM2_RS09470 a67081265928a42f142feb2006aa263f 591 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 456 471 2.2E-26 T 22-04-2016 HRM2_RS09470 a67081265928a42f142feb2006aa263f 591 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 509 521 2.2E-26 T 22-04-2016 HRM2_RS09470 a67081265928a42f142feb2006aa263f 591 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 302 321 2.2E-26 T 22-04-2016 HRM2_RS09470 a67081265928a42f142feb2006aa263f 591 PIRSF PIRSF000732 6 583 3.4E-216 T 22-04-2016 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 HRM2_RS09470 a67081265928a42f142feb2006aa263f 591 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 11 574 9.1E-183 T 22-04-2016 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 HRM2_RS09470 a67081265928a42f142feb2006aa263f 591 SUPERFAMILY SSF51621 264 550 7.59E-104 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HRM2_RS09470 a67081265928a42f142feb2006aa263f 591 Pfam PF00391 PEP-utilising enzyme, mobile domain 161 234 1.4E-21 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS09470 a67081265928a42f142feb2006aa263f 591 PANTHER PTHR22931:SF28 28 559 2.0E-166 T 22-04-2016 HRM2_RS09470 a67081265928a42f142feb2006aa263f 591 Gene3D G3DSA:3.20.20.60 266 578 1.9E-106 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HRM2_RS09470 a67081265928a42f142feb2006aa263f 591 PANTHER PTHR22931 28 559 2.0E-166 T 22-04-2016 HRM2_RS09470 a67081265928a42f142feb2006aa263f 591 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 456 474 - T 22-04-2016 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 HRM2_RS09410 f88f41869619fca07108fe1b1efbba55 187 SMART SM00841 129 184 3.2E-31 T 22-04-2016 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 UniPathway: UPA00345 HRM2_RS09410 f88f41869619fca07108fe1b1efbba55 187 Pfam PF09285 Elongation factor P, C-terminal 129 184 1.1E-24 T 22-04-2016 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 UniPathway: UPA00345 HRM2_RS09410 f88f41869619fca07108fe1b1efbba55 187 Pfam PF01132 Elongation factor P (EF-P) OB domain 69 121 3.5E-18 T 22-04-2016 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 UniPathway: UPA00345 HRM2_RS09410 f88f41869619fca07108fe1b1efbba55 187 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 22-04-2016 IPR013852 Translation elongation factor P/YeiP, conserved site UniPathway: UPA00345 HRM2_RS09410 f88f41869619fca07108fe1b1efbba55 187 SUPERFAMILY SSF50249 65 126 5.57E-15 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS09410 f88f41869619fca07108fe1b1efbba55 187 SUPERFAMILY SSF50104 1 63 5.01E-21 T 22-04-2016 IPR008991 Translation protein SH3-like domain HRM2_RS09410 f88f41869619fca07108fe1b1efbba55 187 PIRSF PIRSF005901 1 186 5.2E-63 T 22-04-2016 IPR020599 Translation elongation factor P/YeiP UniPathway: UPA00345 HRM2_RS09410 f88f41869619fca07108fe1b1efbba55 187 TIGRFAM TIGR00038 efp: translation elongation factor P 3 185 3.9E-73 T 22-04-2016 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 UniPathway: UPA00345 HRM2_RS09410 f88f41869619fca07108fe1b1efbba55 187 SUPERFAMILY SSF50249 128 185 2.06E-18 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS09410 f88f41869619fca07108fe1b1efbba55 187 Hamap MF_00141 Elongation factor P [efp]. 1 185 46.06 T 22-04-2016 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 UniPathway: UPA00345 HRM2_RS09410 f88f41869619fca07108fe1b1efbba55 187 Gene3D G3DSA:2.40.50.140 65 127 6.7E-21 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS09410 f88f41869619fca07108fe1b1efbba55 187 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 4 60 3.2E-26 T 22-04-2016 IPR013185 Translation elongation factor, KOW-like UniPathway: UPA00345 HRM2_RS09410 f88f41869619fca07108fe1b1efbba55 187 Gene3D G3DSA:2.40.50.140 128 185 4.1E-26 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS09410 f88f41869619fca07108fe1b1efbba55 187 PANTHER PTHR30053 1 186 1.1E-81 T 22-04-2016 HRM2_RS09410 f88f41869619fca07108fe1b1efbba55 187 SMART SM01185 67 121 2.9E-23 T 22-04-2016 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 UniPathway: UPA00345 HRM2_RS09410 f88f41869619fca07108fe1b1efbba55 187 Gene3D G3DSA:2.30.30.30 1 63 5.3E-28 T 22-04-2016 IPR014722 Ribosomal protein L2 domain 2 HRM2_RS23650 e4cf6f84aa4ee5adbdc36d3ac73f0210 577 PANTHER PTHR24096 25 575 3.1E-172 T 22-04-2016 HRM2_RS23650 e4cf6f84aa4ee5adbdc36d3ac73f0210 577 ProSitePatterns PS00455 Putative AMP-binding domain signature. 210 221 - T 22-04-2016 IPR020845 AMP-binding, conserved site HRM2_RS23650 e4cf6f84aa4ee5adbdc36d3ac73f0210 577 Gene3D G3DSA:2.30.38.10 394 474 1.5E-23 T 22-04-2016 HRM2_RS23650 e4cf6f84aa4ee5adbdc36d3ac73f0210 577 Pfam PF13193 AMP-binding enzyme C-terminal domain 490 564 3.0E-17 T 22-04-2016 IPR025110 AMP-binding enzyme C-terminal domain HRM2_RS23650 e4cf6f84aa4ee5adbdc36d3ac73f0210 577 SUPERFAMILY SSF56801 15 573 1.44E-147 T 22-04-2016 HRM2_RS23650 e4cf6f84aa4ee5adbdc36d3ac73f0210 577 Gene3D G3DSA:3.40.50.980 215 393 1.0E-42 T 22-04-2016 HRM2_RS23650 e4cf6f84aa4ee5adbdc36d3ac73f0210 577 Gene3D G3DSA:3.30.300.30 477 575 2.8E-32 T 22-04-2016 HRM2_RS23650 e4cf6f84aa4ee5adbdc36d3ac73f0210 577 Gene3D G3DSA:3.40.50.980 27 214 4.6E-38 T 22-04-2016 HRM2_RS23650 e4cf6f84aa4ee5adbdc36d3ac73f0210 577 Pfam PF00501 AMP-binding enzyme 30 480 6.7E-108 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS00515 fdce368d13b2bd8ebfe62f1f4792cdfd 415 Gene3D G3DSA:2.40.160.10 38 415 3.7E-75 T 22-04-2016 IPR023614 Porin domain HRM2_RS00515 fdce368d13b2bd8ebfe62f1f4792cdfd 415 PANTHER PTHR34596 4 415 1.7E-34 T 22-04-2016 HRM2_RS00515 fdce368d13b2bd8ebfe62f1f4792cdfd 415 Pfam PF03573 outer membrane porin, OprD family 39 414 2.8E-35 T 22-04-2016 IPR005318 Outer membrane porin, bacterial GO:0006810|GO:0015288|GO:0016021 HRM2_RS12430 47ad418f15b743209819aeef462643f5 416 PANTHER PTHR13847:SF209 3 265 2.0E-23 T 22-04-2016 HRM2_RS12430 47ad418f15b743209819aeef462643f5 416 Gene3D G3DSA:3.30.70.1400 58 141 6.4E-24 T 22-04-2016 HRM2_RS12430 47ad418f15b743209819aeef462643f5 416 PANTHER PTHR13847 3 265 2.0E-23 T 22-04-2016 HRM2_RS12430 47ad418f15b743209819aeef462643f5 416 Gene3D G3DSA:3.30.1360.120 148 252 2.6E-41 T 22-04-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 HRM2_RS12430 47ad418f15b743209819aeef462643f5 416 Gene3D G3DSA:3.30.1360.120 5 57 2.6E-41 T 22-04-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 HRM2_RS12430 47ad418f15b743209819aeef462643f5 416 Pfam PF01571 Aminomethyltransferase folate-binding domain 10 265 1.5E-66 T 22-04-2016 IPR006222 Glycine cleavage T-protein-like, N-terminal HRM2_RS12430 47ad418f15b743209819aeef462643f5 416 SUPERFAMILY SSF103025 4 298 3.61E-68 T 22-04-2016 HRM2_RS24085 395167ffd1cb185be40ed0891fa9e9c6 344 PANTHER PTHR10909:SF309 220 321 2.4E-20 T 22-04-2016 HRM2_RS24085 395167ffd1cb185be40ed0891fa9e9c6 344 SMART SM00893 19 204 5.3E-37 T 22-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 HRM2_RS24085 395167ffd1cb185be40ed0891fa9e9c6 344 Gene3D G3DSA:3.40.50.620 18 206 1.7E-60 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS24085 395167ffd1cb185be40ed0891fa9e9c6 344 Gene3D G3DSA:3.40.50.1220 214 339 5.7E-41 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HRM2_RS24085 395167ffd1cb185be40ed0891fa9e9c6 344 SUPERFAMILY SSF52467 216 337 1.09E-34 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HRM2_RS24085 395167ffd1cb185be40ed0891fa9e9c6 344 PANTHER PTHR10909 220 321 2.4E-20 T 22-04-2016 HRM2_RS24085 395167ffd1cb185be40ed0891fa9e9c6 344 SUPERFAMILY SSF52402 18 200 9.07E-48 T 22-04-2016 HRM2_RS24085 395167ffd1cb185be40ed0891fa9e9c6 344 PIRSF PIRSF000089 15 343 1.1E-86 T 22-04-2016 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 HRM2_RS24085 395167ffd1cb185be40ed0891fa9e9c6 344 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 219 299 1.2E-26 T 22-04-2016 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal HRM2_RS24085 395167ffd1cb185be40ed0891fa9e9c6 344 Pfam PF01012 Electron transfer flavoprotein domain 21 196 1.2E-38 T 22-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 HRM2_RS03115 46e92d70f385f9ea778a772bfcab9444 248 SUPERFAMILY SSF102198 16 239 2.09E-46 T 22-04-2016 HRM2_RS03115 46e92d70f385f9ea778a772bfcab9444 248 Pfam PF04199 Putative cyclase 19 185 1.7E-28 T 22-04-2016 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|UniPathway: UPA00333 HRM2_RS03115 46e92d70f385f9ea778a772bfcab9444 248 PANTHER PTHR31118 17 242 1.1E-53 T 22-04-2016 HRM2_RS03115 46e92d70f385f9ea778a772bfcab9444 248 PANTHER PTHR31118:SF9 17 242 1.1E-53 T 22-04-2016 HRM2_RS03115 46e92d70f385f9ea778a772bfcab9444 248 Gene3D G3DSA:3.50.30.50 16 241 1.4E-52 T 22-04-2016 HRM2_RS12375 7e1374394e8f6d3ccf7a5363e5cd47e0 936 Gene3D G3DSA:3.40.50.620 12 199 1.3E-140 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS12375 7e1374394e8f6d3ccf7a5363e5cd47e0 936 Gene3D G3DSA:3.40.50.620 402 638 1.3E-140 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS12375 7e1374394e8f6d3ccf7a5363e5cd47e0 936 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 28 642 7.2E-218 T 22-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS12375 7e1374394e8f6d3ccf7a5363e5cd47e0 936 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 929 20.901 T 22-04-2016 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5 HRM2_RS12375 7e1374394e8f6d3ccf7a5363e5cd47e0 936 Gene3D G3DSA:3.90.740.10 206 385 4.5E-55 T 22-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 HRM2_RS12375 7e1374394e8f6d3ccf7a5363e5cd47e0 936 PANTHER PTHR11946:SF11 279 907 0.0 T 22-04-2016 HRM2_RS12375 7e1374394e8f6d3ccf7a5363e5cd47e0 936 PANTHER PTHR11946:SF11 5 255 0.0 T 22-04-2016 HRM2_RS12375 7e1374394e8f6d3ccf7a5363e5cd47e0 936 SUPERFAMILY SSF52374 399 648 5.86E-146 T 22-04-2016 HRM2_RS12375 7e1374394e8f6d3ccf7a5363e5cd47e0 936 SUPERFAMILY SSF52374 1 201 5.86E-146 T 22-04-2016 HRM2_RS12375 7e1374394e8f6d3ccf7a5363e5cd47e0 936 PANTHER PTHR11946 279 907 0.0 T 22-04-2016 HRM2_RS12375 7e1374394e8f6d3ccf7a5363e5cd47e0 936 PANTHER PTHR11946 5 255 0.0 T 22-04-2016 HRM2_RS12375 7e1374394e8f6d3ccf7a5363e5cd47e0 936 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS12375 7e1374394e8f6d3ccf7a5363e5cd47e0 936 Gene3D G3DSA:1.10.730.10 642 828 1.4E-53 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS12375 7e1374394e8f6d3ccf7a5363e5cd47e0 936 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 13 840 8.6E-292 T 22-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 HRM2_RS12375 7e1374394e8f6d3ccf7a5363e5cd47e0 936 SUPERFAMILY SSF50677 203 399 3.66E-55 T 22-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 HRM2_RS12375 7e1374394e8f6d3ccf7a5363e5cd47e0 936 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 397 412 1.0E-31 T 22-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 HRM2_RS12375 7e1374394e8f6d3ccf7a5363e5cd47e0 936 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 1.0E-31 T 22-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 HRM2_RS12375 7e1374394e8f6d3ccf7a5363e5cd47e0 936 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 562 571 1.0E-31 T 22-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 HRM2_RS12375 7e1374394e8f6d3ccf7a5363e5cd47e0 936 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 528 541 1.0E-31 T 22-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 HRM2_RS12375 7e1374394e8f6d3ccf7a5363e5cd47e0 936 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 234 257 1.0E-31 T 22-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 HRM2_RS12375 7e1374394e8f6d3ccf7a5363e5cd47e0 936 Pfam PF08264 Anticodon-binding domain of tRNA 686 839 5.9E-33 T 22-04-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 HRM2_RS12375 7e1374394e8f6d3ccf7a5363e5cd47e0 936 SUPERFAMILY SSF47323 653 931 3.55E-78 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS11810 e8a88956854c7a18ef20800c8cbff657 455 SUPERFAMILY SSF142019 120 311 5.1E-53 T 22-04-2016 HRM2_RS11810 e8a88956854c7a18ef20800c8cbff657 455 Hamap MF_00461 Electron transport complex subunit RsxC [rsxC]. 1 455 134.225 T 22-04-2016 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 HRM2_RS11810 e8a88956854c7a18ef20800c8cbff657 455 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 383 394 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS11810 e8a88956854c7a18ef20800c8cbff657 455 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 422 433 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS11810 e8a88956854c7a18ef20800c8cbff657 455 Pfam PF10531 SLBB domain 303 352 7.7E-12 T 22-04-2016 IPR019554 Soluble ligand binding domain HRM2_RS11810 e8a88956854c7a18ef20800c8cbff657 455 SUPERFAMILY SSF46548 342 451 8.89E-20 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS11810 e8a88956854c7a18ef20800c8cbff657 455 Gene3D G3DSA:1.10.1060.10 368 451 1.2E-17 T 22-04-2016 HRM2_RS11810 e8a88956854c7a18ef20800c8cbff657 455 TIGRFAM TIGR01945 rnfC: electron transport complex, RnfABCDGE type, C subunit 14 450 1.3E-148 T 22-04-2016 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 HRM2_RS11810 e8a88956854c7a18ef20800c8cbff657 455 Pfam PF13183 4Fe-4S dicluster domain 382 436 1.4E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS11810 e8a88956854c7a18ef20800c8cbff657 455 PANTHER PTHR11780 18 451 6.8E-141 T 22-04-2016 HRM2_RS11810 e8a88956854c7a18ef20800c8cbff657 455 Pfam PF13375 RnfC Barrel sandwich hybrid domain 14 113 3.6E-26 T 22-04-2016 IPR026902 RnfC Barrel sandwich hybrid domain HRM2_RS11810 e8a88956854c7a18ef20800c8cbff657 455 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 146 290 1.1E-47 T 22-04-2016 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain HRM2_RS11810 e8a88956854c7a18ef20800c8cbff657 455 PANTHER PTHR11780:SF1 18 451 6.8E-141 T 22-04-2016 HRM2_RS19015 66ffeb71b3c78c48f1e9154fa0a00f7c 387 SUPERFAMILY SSF56645 1 242 6.41E-72 T 22-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 HRM2_RS19015 66ffeb71b3c78c48f1e9154fa0a00f7c 387 SUPERFAMILY SSF47203 230 381 5.32E-49 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS19015 66ffeb71b3c78c48f1e9154fa0a00f7c 387 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 125 137 - T 22-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 HRM2_RS19015 66ffeb71b3c78c48f1e9154fa0a00f7c 387 Gene3D G3DSA:2.40.110.10 123 218 9.3E-35 T 22-04-2016 HRM2_RS19015 66ffeb71b3c78c48f1e9154fa0a00f7c 387 PANTHER PTHR10909 1 376 1.6E-129 T 22-04-2016 HRM2_RS19015 66ffeb71b3c78c48f1e9154fa0a00f7c 387 Gene3D G3DSA:1.20.140.10 219 383 3.3E-61 T 22-04-2016 HRM2_RS19015 66ffeb71b3c78c48f1e9154fa0a00f7c 387 Gene3D G3DSA:1.10.540.10 1 119 9.2E-34 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS19015 66ffeb71b3c78c48f1e9154fa0a00f7c 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 376 2.9E-41 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS19015 66ffeb71b3c78c48f1e9154fa0a00f7c 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 218 3.3E-22 T 22-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 HRM2_RS19015 66ffeb71b3c78c48f1e9154fa0a00f7c 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 119 4.0E-29 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS19015 66ffeb71b3c78c48f1e9154fa0a00f7c 387 PANTHER PTHR10909:SF305 1 376 1.6E-129 T 22-04-2016 HRM2_RS04870 78176329ca6bd54bf0c586cb97dbdf98 452 PANTHER PTHR22912 1 442 1.9E-104 T 22-04-2016 HRM2_RS04870 78176329ca6bd54bf0c586cb97dbdf98 452 SUPERFAMILY SSF55424 324 433 4.98E-21 T 22-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 HRM2_RS04870 78176329ca6bd54bf0c586cb97dbdf98 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 9.5E-25 T 22-04-2016 HRM2_RS04870 78176329ca6bd54bf0c586cb97dbdf98 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 9.5E-25 T 22-04-2016 HRM2_RS04870 78176329ca6bd54bf0c586cb97dbdf98 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 9.5E-25 T 22-04-2016 HRM2_RS04870 78176329ca6bd54bf0c586cb97dbdf98 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 97 115 9.5E-25 T 22-04-2016 HRM2_RS04870 78176329ca6bd54bf0c586cb97dbdf98 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 9.5E-25 T 22-04-2016 HRM2_RS04870 78176329ca6bd54bf0c586cb97dbdf98 452 SUPERFAMILY SSF51905 196 320 9.39E-48 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS04870 78176329ca6bd54bf0c586cb97dbdf98 452 SUPERFAMILY SSF51905 1 160 9.39E-48 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS04870 78176329ca6bd54bf0c586cb97dbdf98 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 168 1.6E-15 T 22-04-2016 HRM2_RS04870 78176329ca6bd54bf0c586cb97dbdf98 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.6E-15 T 22-04-2016 HRM2_RS04870 78176329ca6bd54bf0c586cb97dbdf98 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 1.6E-15 T 22-04-2016 HRM2_RS04870 78176329ca6bd54bf0c586cb97dbdf98 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 276 283 1.6E-15 T 22-04-2016 HRM2_RS04870 78176329ca6bd54bf0c586cb97dbdf98 452 PANTHER PTHR22912:SF140 1 442 1.9E-104 T 22-04-2016 HRM2_RS04870 78176329ca6bd54bf0c586cb97dbdf98 452 Gene3D G3DSA:3.50.50.60 106 315 8.3E-51 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS04870 78176329ca6bd54bf0c586cb97dbdf98 452 Gene3D G3DSA:3.30.390.30 337 447 3.5E-22 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HRM2_RS04870 78176329ca6bd54bf0c586cb97dbdf98 452 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 306 4.8E-57 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS04870 78176329ca6bd54bf0c586cb97dbdf98 452 Gene3D G3DSA:3.50.50.60 1 105 1.8E-21 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS04870 78176329ca6bd54bf0c586cb97dbdf98 452 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 334 432 2.0E-15 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HRM2_RS00125 ff07e92c92834465de056047eba5a53e 626 Pfam PF00672 HAMP domain 177 250 2.9E-7 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS00125 ff07e92c92834465de056047eba5a53e 626 SUPERFAMILY SSF55874 446 618 1.83E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS00125 ff07e92c92834465de056047eba5a53e 626 SUPERFAMILY SSF47384 383 453 4.32E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS00125 ff07e92c92834465de056047eba5a53e 626 SMART SM00091 261 327 5.7E-9 T 22-04-2016 IPR000014 PAS domain HRM2_RS00125 ff07e92c92834465de056047eba5a53e 626 Gene3D G3DSA:3.30.565.10 458 614 7.8E-39 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS00125 ff07e92c92834465de056047eba5a53e 626 Gene3D G3DSA:1.10.287.130 386 453 1.5E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS00125 ff07e92c92834465de056047eba5a53e 626 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 502 614 1.6E-18 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS00125 ff07e92c92834465de056047eba5a53e 626 Pfam PF17203 Single cache domain 3 39 169 1.8E-9 T 22-04-2016 IPR033463 Single cache domain 3 HRM2_RS00125 ff07e92c92834465de056047eba5a53e 626 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 257 373 5.6E-14 T 22-04-2016 IPR000014 PAS domain HRM2_RS00125 ff07e92c92834465de056047eba5a53e 626 SUPERFAMILY SSF158472 194 251 5.1E-5 T 22-04-2016 HRM2_RS00125 ff07e92c92834465de056047eba5a53e 626 PRINTS PR00344 Bacterial sensor protein C-terminal signature 563 573 1.5E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS00125 ff07e92c92834465de056047eba5a53e 626 PRINTS PR00344 Bacterial sensor protein C-terminal signature 576 594 1.5E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS00125 ff07e92c92834465de056047eba5a53e 626 PRINTS PR00344 Bacterial sensor protein C-terminal signature 545 559 1.5E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS00125 ff07e92c92834465de056047eba5a53e 626 PRINTS PR00344 Bacterial sensor protein C-terminal signature 600 613 1.5E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS00125 ff07e92c92834465de056047eba5a53e 626 SMART SM00304 193 254 0.0084 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS00125 ff07e92c92834465de056047eba5a53e 626 Gene3D G3DSA:3.30.450.20 248 369 6.0E-16 T 22-04-2016 HRM2_RS00125 ff07e92c92834465de056047eba5a53e 626 Pfam PF00512 His Kinase A (phospho-acceptor) domain 387 454 1.9E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS00125 ff07e92c92834465de056047eba5a53e 626 Pfam PF13426 PAS domain 272 370 1.5E-9 T 22-04-2016 IPR000014 PAS domain HRM2_RS00125 ff07e92c92834465de056047eba5a53e 626 SMART SM00388 386 457 0.009 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS00125 ff07e92c92834465de056047eba5a53e 626 SUPERFAMILY SSF55785 248 369 5.48E-14 T 22-04-2016 IPR000014 PAS domain HRM2_RS00125 ff07e92c92834465de056047eba5a53e 626 PANTHER PTHR24423 20 28 3.3E-69 T 22-04-2016 HRM2_RS00125 ff07e92c92834465de056047eba5a53e 626 PANTHER PTHR24423 245 626 3.3E-69 T 22-04-2016 HRM2_RS00125 ff07e92c92834465de056047eba5a53e 626 SMART SM00387 499 616 1.1E-24 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS11370 bec50bfaea3d386c2da6a68a4db0e880 152 PANTHER PTHR10472 2 146 3.3E-67 T 22-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 HRM2_RS11370 bec50bfaea3d386c2da6a68a4db0e880 152 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 34.086 T 22-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 HRM2_RS11370 bec50bfaea3d386c2da6a68a4db0e880 152 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 4.3E-52 T 22-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 HRM2_RS11370 bec50bfaea3d386c2da6a68a4db0e880 152 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 145 3.0E-60 T 22-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 HRM2_RS11370 bec50bfaea3d386c2da6a68a4db0e880 152 Gene3D G3DSA:3.50.80.10 1 145 9.9E-57 T 22-04-2016 IPR023509 D-Tyr tRNAtyr deacylase-like domain HRM2_RS11370 bec50bfaea3d386c2da6a68a4db0e880 152 SUPERFAMILY SSF69500 1 145 9.42E-55 T 22-04-2016 IPR023509 D-Tyr tRNAtyr deacylase-like domain HRM2_RS18525 70079ed785b63c51524e0b9ec585b1e1 150 Gene3D G3DSA:3.10.129.10 13 143 3.5E-30 T 22-04-2016 IPR029069 HotDog domain HRM2_RS18525 70079ed785b63c51524e0b9ec585b1e1 150 PANTHER PTHR12418 21 140 9.5E-20 T 22-04-2016 HRM2_RS18525 70079ed785b63c51524e0b9ec585b1e1 150 Pfam PF03061 Thioesterase superfamily 52 125 9.8E-12 T 22-04-2016 IPR006683 Thioesterase domain HRM2_RS18525 70079ed785b63c51524e0b9ec585b1e1 150 SUPERFAMILY SSF54637 17 143 1.55E-27 T 22-04-2016 IPR029069 HotDog domain HRM2_RS18525 70079ed785b63c51524e0b9ec585b1e1 150 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 26 129 2.4E-13 T 22-04-2016 IPR003736 Phenylacetic acid degradation-related domain HRM2_RS04570 dca03834652745f8bb6a3f2754b3b8c0 224 SUPERFAMILY SSF55821 10 214 7.02E-53 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain HRM2_RS04570 dca03834652745f8bb6a3f2754b3b8c0 224 Pfam PF01300 Telomere recombination 28 203 4.6E-47 T 22-04-2016 IPR006070 YrdC-like domain GO:0003725 HRM2_RS04570 dca03834652745f8bb6a3f2754b3b8c0 224 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 13 213 1.3E-57 T 22-04-2016 IPR006070 YrdC-like domain GO:0003725 HRM2_RS04570 dca03834652745f8bb6a3f2754b3b8c0 224 Gene3D G3DSA:3.90.870.10 9 210 6.0E-61 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain HRM2_RS04570 dca03834652745f8bb6a3f2754b3b8c0 224 PANTHER PTHR17490 9 210 2.6E-57 T 22-04-2016 HRM2_RS08550 c25efe793a64274e76948b6072b1ddf8 273 SMART SM01211 3 269 1.4E-121 T 22-04-2016 HRM2_RS08550 c25efe793a64274e76948b6072b1ddf8 273 PANTHER PTHR10099 1 272 2.7E-81 T 22-04-2016 HRM2_RS08550 c25efe793a64274e76948b6072b1ddf8 273 SUPERFAMILY SSF52317 1 269 1.39E-70 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS08550 c25efe793a64274e76948b6072b1ddf8 273 Gene3D G3DSA:3.40.50.880 11 230 3.1E-18 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS08550 c25efe793a64274e76948b6072b1ddf8 273 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 3 269 3.0E-90 T 22-04-2016 HRM2_RS08550 c25efe793a64274e76948b6072b1ddf8 273 PIRSF PIRSF001586 2 272 5.0E-75 T 22-04-2016 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 HRM2_RS11890 02ee114e8ee5bff9ec1ad3fd37d8250d 568 Pfam PF11741 AMIN domain 202 284 1.9E-9 T 22-04-2016 IPR021731 AMIN domain HRM2_RS11890 02ee114e8ee5bff9ec1ad3fd37d8250d 568 Gene3D G3DSA:3.40.630.40 478 561 1.4E-54 T 22-04-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 HRM2_RS11890 02ee114e8ee5bff9ec1ad3fd37d8250d 568 Gene3D G3DSA:3.40.630.40 344 439 1.4E-54 T 22-04-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 HRM2_RS11890 02ee114e8ee5bff9ec1ad3fd37d8250d 568 SUPERFAMILY SSF53187 344 440 9.1E-50 T 22-04-2016 HRM2_RS11890 02ee114e8ee5bff9ec1ad3fd37d8250d 568 SUPERFAMILY SSF53187 479 560 9.1E-50 T 22-04-2016 HRM2_RS11890 02ee114e8ee5bff9ec1ad3fd37d8250d 568 PANTHER PTHR30404:SF0 288 561 3.8E-67 T 22-04-2016 HRM2_RS11890 02ee114e8ee5bff9ec1ad3fd37d8250d 568 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 345 557 2.8E-48 T 22-04-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 HRM2_RS11890 02ee114e8ee5bff9ec1ad3fd37d8250d 568 PANTHER PTHR30404 288 561 3.8E-67 T 22-04-2016 HRM2_RS11890 02ee114e8ee5bff9ec1ad3fd37d8250d 568 SMART SM00646 406 557 1.5E-34 T 22-04-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 HRM2_RS14725 e74358617ae68f714515a90487c5a7d0 464 PANTHER PTHR10668:SF63 3 430 1.3E-133 T 22-04-2016 HRM2_RS14725 e74358617ae68f714515a90487c5a7d0 464 SUPERFAMILY SSF51905 1 296 1.29E-29 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS14725 e74358617ae68f714515a90487c5a7d0 464 Gene3D G3DSA:3.50.50.60 198 318 4.3E-23 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS14725 e74358617ae68f714515a90487c5a7d0 464 Gene3D G3DSA:3.50.50.60 1 103 4.3E-23 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS14725 e74358617ae68f714515a90487c5a7d0 464 Pfam PF01593 Flavin containing amine oxidoreductase 11 359 4.4E-11 T 22-04-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 HRM2_RS14725 e74358617ae68f714515a90487c5a7d0 464 PANTHER PTHR10668 3 430 1.3E-133 T 22-04-2016 HRM2_RS10960 f8694cb4bdecda9b55c2ddfeae582c13 533 SUPERFAMILY SSF53822 190 529 3.87E-60 T 22-04-2016 IPR028082 Periplasmic binding protein-like I HRM2_RS10960 f8694cb4bdecda9b55c2ddfeae582c13 533 SUPERFAMILY SSF48452 64 101 4.75E-6 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS10960 f8694cb4bdecda9b55c2ddfeae582c13 533 SUPERFAMILY SSF48452 134 176 4.75E-6 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS10960 f8694cb4bdecda9b55c2ddfeae582c13 533 PANTHER PTHR30483 190 531 5.2E-45 T 22-04-2016 HRM2_RS10960 f8694cb4bdecda9b55c2ddfeae582c13 533 Pfam PF13458 Periplasmic binding protein 190 526 1.5E-40 T 22-04-2016 IPR028081 Leucine-binding protein domain HRM2_RS10960 f8694cb4bdecda9b55c2ddfeae582c13 533 Gene3D G3DSA:3.40.50.2300 190 368 9.3E-33 T 22-04-2016 HRM2_RS10960 f8694cb4bdecda9b55c2ddfeae582c13 533 PANTHER PTHR30483:SF6 190 531 5.2E-45 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HRM2_RS10960 f8694cb4bdecda9b55c2ddfeae582c13 533 Gene3D G3DSA:1.25.40.10 63 99 2.2E-6 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS10960 f8694cb4bdecda9b55c2ddfeae582c13 533 Gene3D G3DSA:1.25.40.10 134 169 2.2E-6 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS15320 340d6d22dbe16ca10e8537dd1c02c51a 349 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 7 347 1.1E-125 T 22-04-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HRM2_RS15320 340d6d22dbe16ca10e8537dd1c02c51a 349 SUPERFAMILY SSF102114 99 314 8.24E-12 T 22-04-2016 HRM2_RS15320 340d6d22dbe16ca10e8537dd1c02c51a 349 Gene3D G3DSA:3.20.20.70 104 329 4.7E-16 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS15320 340d6d22dbe16ca10e8537dd1c02c51a 349 PIRSF PIRSF006004 4 348 1.5E-132 T 22-04-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HRM2_RS15320 340d6d22dbe16ca10e8537dd1c02c51a 349 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 5 349 70.09 T 22-04-2016 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HRM2_RS15320 340d6d22dbe16ca10e8537dd1c02c51a 349 PANTHER PTHR30544 8 346 2.1E-152 T 22-04-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HRM2_RS15320 340d6d22dbe16ca10e8537dd1c02c51a 349 Pfam PF04055 Radical SAM superfamily 109 276 1.5E-14 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS18705 78a22546f2117dc298863629532a8c28 376 PANTHER PTHR11751:SF366 18 349 1.4E-69 T 22-04-2016 HRM2_RS18705 78a22546f2117dc298863629532a8c28 376 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 14 351 2.6E-83 T 22-04-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9|UniPathway: UPA00031 HRM2_RS18705 78a22546f2117dc298863629532a8c28 376 SUPERFAMILY SSF53383 11 369 1.03E-74 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS18705 78a22546f2117dc298863629532a8c28 376 PANTHER PTHR11751 18 349 1.4E-69 T 22-04-2016 HRM2_RS18705 78a22546f2117dc298863629532a8c28 376 Pfam PF00155 Aminotransferase class I and II 43 363 4.0E-48 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HRM2_RS18705 78a22546f2117dc298863629532a8c28 376 Gene3D G3DSA:3.40.640.10 51 268 5.5E-62 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS18705 78a22546f2117dc298863629532a8c28 376 Gene3D G3DSA:3.90.1150.10 269 369 1.5E-15 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS24435 90678b9be6abdaed4320721abd32ab7e 147 Gene3D G3DSA:2.60.40.790 17 143 3.3E-26 T 22-04-2016 IPR008978 HSP20-like chaperone HRM2_RS24435 90678b9be6abdaed4320721abd32ab7e 147 PANTHER PTHR11527:SF96 18 143 8.9E-23 T 22-04-2016 HRM2_RS24435 90678b9be6abdaed4320721abd32ab7e 147 PANTHER PTHR11527 18 143 8.9E-23 T 22-04-2016 IPR031107 Small heat shock protein HSP20 HRM2_RS24435 90678b9be6abdaed4320721abd32ab7e 147 SUPERFAMILY SSF49764 23 144 1.92E-26 T 22-04-2016 IPR008978 HSP20-like chaperone HRM2_RS24435 90678b9be6abdaed4320721abd32ab7e 147 Pfam PF00011 Hsp20/alpha crystallin family 45 140 8.3E-13 T 22-04-2016 IPR002068 Alpha crystallin/Hsp20 domain HRM2_RS15865 2a19890730602483f479e16cbee4d352 342 Pfam PF02424 ApbE family 41 323 5.6E-80 T 22-04-2016 IPR024932 Flavin transferase ApbE GO:0017013 HRM2_RS15865 2a19890730602483f479e16cbee4d352 342 SUPERFAMILY SSF143631 34 333 3.14E-90 T 22-04-2016 IPR003374 ApbE-like domain HRM2_RS15865 2a19890730602483f479e16cbee4d352 342 PANTHER PTHR30040:SF3 1 341 1.5E-106 T 22-04-2016 HRM2_RS15865 2a19890730602483f479e16cbee4d352 342 PANTHER PTHR30040 1 341 1.5E-106 T 22-04-2016 HRM2_RS15865 2a19890730602483f479e16cbee4d352 342 PIRSF PIRSF006268 3 341 1.0E-89 T 22-04-2016 IPR024932 Flavin transferase ApbE GO:0017013 HRM2_RS11645 63d94be8043546f0be1a82f9fffa2d40 826 SMART SM00382 349 495 0.0081 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS11645 63d94be8043546f0be1a82f9fffa2d40 826 PANTHER PTHR10887 615 678 1.6E-79 T 22-04-2016 HRM2_RS11645 63d94be8043546f0be1a82f9fffa2d40 826 PANTHER PTHR10887 333 542 1.6E-79 T 22-04-2016 HRM2_RS11645 63d94be8043546f0be1a82f9fffa2d40 826 PANTHER PTHR10887 747 820 1.6E-79 T 22-04-2016 HRM2_RS11645 63d94be8043546f0be1a82f9fffa2d40 826 PANTHER PTHR10887 108 141 1.6E-79 T 22-04-2016 HRM2_RS11645 63d94be8043546f0be1a82f9fffa2d40 826 SUPERFAMILY SSF52540 191 492 1.38E-39 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11645 63d94be8043546f0be1a82f9fffa2d40 826 Gene3D G3DSA:3.40.50.300 738 798 4.1E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11645 63d94be8043546f0be1a82f9fffa2d40 826 Gene3D G3DSA:3.40.50.300 161 170 4.1E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11645 63d94be8043546f0be1a82f9fffa2d40 826 SUPERFAMILY SSF47781 88 168 1.27E-10 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 HRM2_RS11645 63d94be8043546f0be1a82f9fffa2d40 826 Pfam PF14520 Helix-hairpin-helix domain 100 144 2.6E-7 T 22-04-2016 HRM2_RS11645 63d94be8043546f0be1a82f9fffa2d40 826 Gene3D G3DSA:3.40.50.300 333 512 8.0E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11645 63d94be8043546f0be1a82f9fffa2d40 826 Pfam PF14490 Helix-hairpin-helix containing domain 150 240 1.7E-27 T 22-04-2016 IPR029493 RecD helicase-like helix-hairpin-helix domain HRM2_RS11645 63d94be8043546f0be1a82f9fffa2d40 826 Gene3D G3DSA:1.10.150.20 100 144 5.4E-6 T 22-04-2016 HRM2_RS11645 63d94be8043546f0be1a82f9fffa2d40 826 Pfam PF13604 AAA domain 336 512 9.4E-44 T 22-04-2016 HRM2_RS11645 63d94be8043546f0be1a82f9fffa2d40 826 PANTHER PTHR10887:SF284 615 678 1.6E-79 T 22-04-2016 HRM2_RS11645 63d94be8043546f0be1a82f9fffa2d40 826 PANTHER PTHR10887:SF284 333 542 1.6E-79 T 22-04-2016 HRM2_RS11645 63d94be8043546f0be1a82f9fffa2d40 826 PANTHER PTHR10887:SF284 747 820 1.6E-79 T 22-04-2016 HRM2_RS11645 63d94be8043546f0be1a82f9fffa2d40 826 PANTHER PTHR10887:SF284 108 141 1.6E-79 T 22-04-2016 HRM2_RS11645 63d94be8043546f0be1a82f9fffa2d40 826 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 10 823 25.954 T 22-04-2016 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 HRM2_RS11645 63d94be8043546f0be1a82f9fffa2d40 826 SUPERFAMILY SSF52540 643 807 3.11E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11645 63d94be8043546f0be1a82f9fffa2d40 826 SUPERFAMILY SSF52540 445 510 3.11E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11645 63d94be8043546f0be1a82f9fffa2d40 826 Pfam PF13538 UvrD-like helicase C-terminal domain 747 792 3.7E-18 T 22-04-2016 IPR027785 UvrD-like helicase C-terminal domain HRM2_RS17940 55c3ffc293295dc139805b438edba3cd 207 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 186 6.0E-9 T 22-04-2016 HRM2_RS17940 55c3ffc293295dc139805b438edba3cd 207 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 35 193 24.827 T 22-04-2016 IPR022973 Ribosomal protein L10 HRM2_RS17940 55c3ffc293295dc139805b438edba3cd 207 PANTHER PTHR11560 35 205 5.9E-51 T 22-04-2016 HRM2_RS17940 55c3ffc293295dc139805b438edba3cd 207 ProSitePatterns PS01109 Ribosomal protein L10 signature. 40 74 - T 22-04-2016 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17940 55c3ffc293295dc139805b438edba3cd 207 Pfam PF00466 Ribosomal protein L10 38 132 8.6E-24 T 22-04-2016 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 HRM2_RS17940 55c3ffc293295dc139805b438edba3cd 207 SUPERFAMILY SSF160369 36 204 3.27E-52 T 22-04-2016 HRM2_RS14630 728a739a1253c1c4d41e2e00930e77d9 115 PANTHER PTHR30177 1 109 1.5E-37 T 22-04-2016 HRM2_RS14630 728a739a1253c1c4d41e2e00930e77d9 115 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 1 100 2.2E-14 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS14630 728a739a1253c1c4d41e2e00930e77d9 115 SUPERFAMILY SSF161098 1 90 6.67E-22 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS14630 728a739a1253c1c4d41e2e00930e77d9 115 PANTHER PTHR30177:SF4 1 109 1.5E-37 T 22-04-2016 HRM2_RS14630 728a739a1253c1c4d41e2e00930e77d9 115 Gene3D G3DSA:1.10.3720.10 1 102 4.5E-18 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS18020 43d19a7d581318ec4fd06957bcea263b 366 Pfam PF01339 CheB methylesterase 179 360 3.7E-61 T 22-04-2016 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 HRM2_RS18020 43d19a7d581318ec4fd06957bcea263b 366 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 4 365 34.653 T 22-04-2016 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 HRM2_RS18020 43d19a7d581318ec4fd06957bcea263b 366 PANTHER PTHR24421 1 366 8.8E-111 T 22-04-2016 HRM2_RS18020 43d19a7d581318ec4fd06957bcea263b 366 SUPERFAMILY SSF52172 1 120 3.13E-26 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS18020 43d19a7d581318ec4fd06957bcea263b 366 Gene3D G3DSA:3.40.50.180 176 364 2.9E-74 T 22-04-2016 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 HRM2_RS18020 43d19a7d581318ec4fd06957bcea263b 366 SUPERFAMILY SSF52738 176 363 6.02E-64 T 22-04-2016 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 HRM2_RS18020 43d19a7d581318ec4fd06957bcea263b 366 Pfam PF00072 Response regulator receiver domain 6 110 3.3E-22 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18020 43d19a7d581318ec4fd06957bcea263b 366 SMART SM00448 4 119 1.2E-22 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18020 43d19a7d581318ec4fd06957bcea263b 366 Gene3D G3DSA:3.40.50.2300 3 119 8.1E-26 T 22-04-2016 HRM2_RS18020 43d19a7d581318ec4fd06957bcea263b 366 PANTHER PTHR24421:SF16 1 366 8.8E-111 T 22-04-2016 HRM2_RS18020 43d19a7d581318ec4fd06957bcea263b 366 PIRSF PIRSF000876 1 366 1.9E-118 T 22-04-2016 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 HRM2_RS10800 bb58795fa58ab5258220b4f1c10c9712 432 SMART SM00116 380 427 1.4E-9 T 22-04-2016 IPR000644 CBS domain HRM2_RS10800 bb58795fa58ab5258220b4f1c10c9712 432 SMART SM00116 317 365 2.2E-9 T 22-04-2016 IPR000644 CBS domain HRM2_RS10800 bb58795fa58ab5258220b4f1c10c9712 432 SUPERFAMILY SSF64182 3 286 1.31E-43 T 22-04-2016 HRM2_RS10800 bb58795fa58ab5258220b4f1c10c9712 432 SUPERFAMILY SSF54631 307 428 4.67E-32 T 22-04-2016 HRM2_RS10800 bb58795fa58ab5258220b4f1c10c9712 432 PANTHER PTHR11911 310 428 5.1E-28 T 22-04-2016 HRM2_RS10800 bb58795fa58ab5258220b4f1c10c9712 432 Pfam PF00571 CBS domain 373 425 1.6E-13 T 22-04-2016 IPR000644 CBS domain HRM2_RS10800 bb58795fa58ab5258220b4f1c10c9712 432 Pfam PF00571 CBS domain 311 362 2.1E-9 T 22-04-2016 IPR000644 CBS domain HRM2_RS10800 bb58795fa58ab5258220b4f1c10c9712 432 Pfam PF01368 DHH family 3 142 2.6E-6 T 22-04-2016 IPR001667 DDH domain HRM2_RS10800 bb58795fa58ab5258220b4f1c10c9712 432 Gene3D G3DSA:3.20.20.70 250 426 2.9E-34 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS10800 bb58795fa58ab5258220b4f1c10c9712 432 Gene3D G3DSA:3.90.1640.10 3 181 1.5E-22 T 22-04-2016 HRM2_RS03585 0b979a271dad5a0e75b2fd0dd8aac555 220 SUPERFAMILY SSF47644 6 83 1.7E-10 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain HRM2_RS03585 0b979a271dad5a0e75b2fd0dd8aac555 220 Gene3D G3DSA:3.40.50.280 92 218 1.4E-37 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS03585 0b979a271dad5a0e75b2fd0dd8aac555 220 Pfam PF02607 B12 binding domain 11 83 1.2E-8 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain HRM2_RS03585 0b979a271dad5a0e75b2fd0dd8aac555 220 SUPERFAMILY SSF52242 94 217 1.96E-34 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS03585 0b979a271dad5a0e75b2fd0dd8aac555 220 Pfam PF02310 B12 binding domain 98 206 3.3E-16 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS03585 0b979a271dad5a0e75b2fd0dd8aac555 220 Gene3D G3DSA:1.10.1240.10 7 84 1.0E-8 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain HRM2_RS00430 642de68c036c78b543e51cefa93ac3a4 1052 SUPERFAMILY SSF82866 799 1022 3.53E-48 T 22-04-2016 HRM2_RS00430 642de68c036c78b543e51cefa93ac3a4 1052 SUPERFAMILY SSF82693 49 137 6.02E-18 T 22-04-2016 HRM2_RS00430 642de68c036c78b543e51cefa93ac3a4 1052 PRINTS PR00702 Acriflavin resistance protein family signature 389 413 7.8E-23 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS00430 642de68c036c78b543e51cefa93ac3a4 1052 PRINTS PR00702 Acriflavin resistance protein family signature 47 65 7.8E-23 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS00430 642de68c036c78b543e51cefa93ac3a4 1052 PRINTS PR00702 Acriflavin resistance protein family signature 335 358 7.8E-23 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS00430 642de68c036c78b543e51cefa93ac3a4 1052 PRINTS PR00702 Acriflavin resistance protein family signature 442 465 7.8E-23 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS00430 642de68c036c78b543e51cefa93ac3a4 1052 SUPERFAMILY SSF82714 725 798 8.89E-10 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS00430 642de68c036c78b543e51cefa93ac3a4 1052 Gene3D G3DSA:1.20.1640.10 295 497 1.5E-48 T 22-04-2016 HRM2_RS00430 642de68c036c78b543e51cefa93ac3a4 1052 SUPERFAMILY SSF82714 187 271 2.88E-15 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS00430 642de68c036c78b543e51cefa93ac3a4 1052 PANTHER PTHR32063:SF33 10 1026 0.0 T 22-04-2016 HRM2_RS00430 642de68c036c78b543e51cefa93ac3a4 1052 Gene3D G3DSA:3.30.70.1430 50 140 2.4E-19 T 22-04-2016 HRM2_RS00430 642de68c036c78b543e51cefa93ac3a4 1052 SUPERFAMILY SSF82866 299 493 7.59E-40 T 22-04-2016 HRM2_RS00430 642de68c036c78b543e51cefa93ac3a4 1052 Gene3D G3DSA:3.30.2090.10 186 273 1.3E-14 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS00430 642de68c036c78b543e51cefa93ac3a4 1052 Gene3D G3DSA:3.30.2090.10 725 798 1.3E-9 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS00430 642de68c036c78b543e51cefa93ac3a4 1052 Pfam PF00873 AcrB/AcrD/AcrF family 15 1020 2.4E-165 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS00430 642de68c036c78b543e51cefa93ac3a4 1052 Gene3D G3DSA:1.10.3850.10 804 1021 2.8E-59 T 22-04-2016 HRM2_RS00430 642de68c036c78b543e51cefa93ac3a4 1052 SUPERFAMILY SSF82693 273 329 2.09E-14 T 22-04-2016 HRM2_RS00430 642de68c036c78b543e51cefa93ac3a4 1052 SUPERFAMILY SSF82693 152 186 2.09E-14 T 22-04-2016 HRM2_RS00430 642de68c036c78b543e51cefa93ac3a4 1052 PANTHER PTHR32063 10 1026 0.0 T 22-04-2016 HRM2_RS05225 6d36117757260b3ff7896f0c2d13dfec 631 Gene3D G3DSA:3.90.70.10 49 253 1.7E-24 T 22-04-2016 HRM2_RS05225 6d36117757260b3ff7896f0c2d13dfec 631 PANTHER PTHR12411 27 233 5.1E-18 T 22-04-2016 IPR013128 Peptidase C1A GO:0008234 HRM2_RS05225 6d36117757260b3ff7896f0c2d13dfec 631 SUPERFAMILY SSF54001 49 254 4.91E-29 T 22-04-2016 HRM2_RS05225 6d36117757260b3ff7896f0c2d13dfec 631 Pfam PF00112 Papain family cysteine protease 49 235 5.0E-11 T 22-04-2016 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 HRM2_RS05225 6d36117757260b3ff7896f0c2d13dfec 631 SUPERFAMILY SSF53474 445 509 3.0E-5 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS05225 6d36117757260b3ff7896f0c2d13dfec 631 SMART SM00645 40 257 5.8E-4 T 22-04-2016 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 HRM2_RS05225 6d36117757260b3ff7896f0c2d13dfec 631 PANTHER PTHR12411:SF101 27 233 5.1E-18 T 22-04-2016 IPR033158 Cathepsin W GO:0006508|GO:0008234 HRM2_RS17250 40367f5542821cab4915e9c05c7a5c20 386 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 21 45 6.7E-5 T 22-04-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal HRM2_RS17250 40367f5542821cab4915e9c05c7a5c20 386 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 206 225 7.6E-7 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS17250 40367f5542821cab4915e9c05c7a5c20 386 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 126 139 7.6E-7 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS17250 40367f5542821cab4915e9c05c7a5c20 386 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 330 356 7.6E-7 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS17250 40367f5542821cab4915e9c05c7a5c20 386 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 159 175 7.6E-7 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS17250 40367f5542821cab4915e9c05c7a5c20 386 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 79 100 7.6E-7 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS17250 40367f5542821cab4915e9c05c7a5c20 386 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 20 43 2.4E-5 T 22-04-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal HRM2_RS17250 40367f5542821cab4915e9c05c7a5c20 386 Gene3D G3DSA:3.40.190.10 309 349 8.0E-15 T 22-04-2016 HRM2_RS17250 40367f5542821cab4915e9c05c7a5c20 386 Gene3D G3DSA:3.40.190.10 53 168 8.0E-15 T 22-04-2016 HRM2_RS17250 40367f5542821cab4915e9c05c7a5c20 386 PANTHER PTHR30222 10 332 1.5E-28 T 22-04-2016 HRM2_RS17250 40367f5542821cab4915e9c05c7a5c20 386 PANTHER PTHR30222:SF5 10 332 1.5E-28 T 22-04-2016 HRM2_RS17250 40367f5542821cab4915e9c05c7a5c20 386 Gene3D G3DSA:3.40.190.10 169 308 1.3E-27 T 22-04-2016 HRM2_RS17250 40367f5542821cab4915e9c05c7a5c20 386 Pfam PF13416 Bacterial extracellular solute-binding protein 75 351 4.6E-26 T 22-04-2016 HRM2_RS17250 40367f5542821cab4915e9c05c7a5c20 386 SUPERFAMILY SSF53850 54 385 2.67E-51 T 22-04-2016 HRM2_RS06355 4ceebb04e90b15dfda1d8a34a323ac89 626 SUPERFAMILY SSF52821 48 159 9.17E-25 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS06355 4ceebb04e90b15dfda1d8a34a323ac89 626 PANTHER PTHR11364:SF15 287 596 3.3E-57 T 22-04-2016 HRM2_RS06355 4ceebb04e90b15dfda1d8a34a323ac89 626 Gene3D G3DSA:3.40.250.10 461 595 4.9E-21 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS06355 4ceebb04e90b15dfda1d8a34a323ac89 626 SUPERFAMILY SSF52821 170 288 1.06E-29 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS06355 4ceebb04e90b15dfda1d8a34a323ac89 626 SUPERFAMILY SSF52821 335 453 2.1E-29 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS06355 4ceebb04e90b15dfda1d8a34a323ac89 626 SMART SM00450 324 441 8.5E-16 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS06355 4ceebb04e90b15dfda1d8a34a323ac89 626 SMART SM00450 466 599 4.6E-14 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS06355 4ceebb04e90b15dfda1d8a34a323ac89 626 SMART SM00450 173 292 1.7E-19 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS06355 4ceebb04e90b15dfda1d8a34a323ac89 626 SMART SM00450 37 150 6.3E-16 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS06355 4ceebb04e90b15dfda1d8a34a323ac89 626 Gene3D G3DSA:3.40.250.10 45 161 4.0E-29 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS06355 4ceebb04e90b15dfda1d8a34a323ac89 626 Gene3D G3DSA:3.40.250.10 300 453 1.4E-39 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS06355 4ceebb04e90b15dfda1d8a34a323ac89 626 PANTHER PTHR11364 287 596 3.3E-57 T 22-04-2016 HRM2_RS06355 4ceebb04e90b15dfda1d8a34a323ac89 626 Gene3D G3DSA:3.40.250.10 176 289 1.1E-29 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS06355 4ceebb04e90b15dfda1d8a34a323ac89 626 Pfam PF00581 Rhodanese-like domain 178 288 3.5E-14 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS06355 4ceebb04e90b15dfda1d8a34a323ac89 626 Pfam PF00581 Rhodanese-like domain 48 146 5.1E-16 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS06355 4ceebb04e90b15dfda1d8a34a323ac89 626 Pfam PF00581 Rhodanese-like domain 467 595 4.9E-10 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS06355 4ceebb04e90b15dfda1d8a34a323ac89 626 Pfam PF00581 Rhodanese-like domain 352 437 1.2E-15 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS06355 4ceebb04e90b15dfda1d8a34a323ac89 626 SUPERFAMILY SSF52821 469 595 7.6E-22 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS01090 2dabbdef0fd2bb22b4aac31ba10623e1 171 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 2 170 3.9E-57 T 22-04-2016 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 HRM2_RS01090 2dabbdef0fd2bb22b4aac31ba10623e1 171 PANTHER PTHR30069 1 170 5.2E-47 T 22-04-2016 HRM2_RS01090 2dabbdef0fd2bb22b4aac31ba10623e1 171 Gene3D G3DSA:3.40.50.300 2 170 5.2E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01090 2dabbdef0fd2bb22b4aac31ba10623e1 171 SUPERFAMILY SSF52540 2 170 5.11E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01090 2dabbdef0fd2bb22b4aac31ba10623e1 171 PIRSF PIRSF015617 1 171 2.9E-57 T 22-04-2016 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 HRM2_RS04490 e2533715787cb1b1dbddc1ede2ffa4d0 356 SUPERFAMILY SSF81271 272 352 6.98E-32 T 22-04-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 HRM2_RS04490 e2533715787cb1b1dbddc1ede2ffa4d0 356 Gene3D G3DSA:1.10.150.300 122 192 1.6E-20 T 22-04-2016 IPR023192 TGS-like domain HRM2_RS04490 e2533715787cb1b1dbddc1ede2ffa4d0 356 Gene3D G3DSA:3.10.20.30 251 356 1.9E-38 T 22-04-2016 IPR012675 Beta-grasp domain HRM2_RS04490 e2533715787cb1b1dbddc1ede2ffa4d0 356 PANTHER PTHR23305 1 356 8.0E-92 T 22-04-2016 HRM2_RS04490 e2533715787cb1b1dbddc1ede2ffa4d0 356 Pfam PF06071 Protein of unknown function (DUF933) 272 354 3.0E-35 T 22-04-2016 IPR013029 Domain of unknown function DUF933 HRM2_RS04490 e2533715787cb1b1dbddc1ede2ffa4d0 356 Gene3D G3DSA:3.40.50.300 193 241 1.9E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04490 e2533715787cb1b1dbddc1ede2ffa4d0 356 Gene3D G3DSA:3.40.50.300 1 121 1.9E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04490 e2533715787cb1b1dbddc1ede2ffa4d0 356 PIRSF PIRSF006641 1 356 4.7E-90 T 22-04-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 HRM2_RS04490 e2533715787cb1b1dbddc1ede2ffa4d0 356 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 2 355 1.1E-85 T 22-04-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 HRM2_RS04490 e2533715787cb1b1dbddc1ede2ffa4d0 356 SUPERFAMILY SSF52540 1 292 8.18E-39 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04490 e2533715787cb1b1dbddc1ede2ffa4d0 356 PANTHER PTHR23305:SF12 1 356 8.0E-92 T 22-04-2016 HRM2_RS01585 41358665af6d284db2bec958b9b5dc25 152 Pfam PF13635 Domain of unknown function (DUF4143) 66 131 2.4E-7 T 22-04-2016 IPR025420 Domain of unknown function DUF4143 HRM2_RS07305 d55a80c0fd9b82771efaef5e7296abc4 1961 SUPERFAMILY SSF52540 108 168 5.95E-27 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07305 d55a80c0fd9b82771efaef5e7296abc4 1961 SUPERFAMILY SSF52540 974 1117 5.95E-27 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07305 d55a80c0fd9b82771efaef5e7296abc4 1961 PANTHER PTHR24031:SF280 94 198 6.1E-25 T 22-04-2016 HRM2_RS07305 d55a80c0fd9b82771efaef5e7296abc4 1961 PANTHER PTHR24031:SF280 991 1055 6.1E-25 T 22-04-2016 HRM2_RS07305 d55a80c0fd9b82771efaef5e7296abc4 1961 PANTHER PTHR24031:SF280 225 356 6.1E-25 T 22-04-2016 HRM2_RS07305 d55a80c0fd9b82771efaef5e7296abc4 1961 Pfam PF00270 DEAD/DEAH box helicase 96 302 1.9E-12 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HRM2_RS07305 d55a80c0fd9b82771efaef5e7296abc4 1961 Pfam PF00271 Helicase conserved C-terminal domain 986 1054 1.6E-10 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS07305 d55a80c0fd9b82771efaef5e7296abc4 1961 Gene3D G3DSA:3.40.50.300 94 303 4.1E-24 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07305 d55a80c0fd9b82771efaef5e7296abc4 1961 PANTHER PTHR24031 94 198 6.1E-25 T 22-04-2016 HRM2_RS07305 d55a80c0fd9b82771efaef5e7296abc4 1961 PANTHER PTHR24031 991 1055 6.1E-25 T 22-04-2016 HRM2_RS07305 d55a80c0fd9b82771efaef5e7296abc4 1961 PANTHER PTHR24031 225 356 6.1E-25 T 22-04-2016 HRM2_RS07305 d55a80c0fd9b82771efaef5e7296abc4 1961 Gene3D G3DSA:3.40.50.300 984 1098 2.1E-21 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07305 d55a80c0fd9b82771efaef5e7296abc4 1961 Gene3D G3DSA:3.40.50.300 667 695 2.1E-21 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07305 d55a80c0fd9b82771efaef5e7296abc4 1961 SMART SM00490 975 1056 7.7E-13 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS07305 d55a80c0fd9b82771efaef5e7296abc4 1961 SUPERFAMILY SSF52540 92 188 1.98E-23 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07305 d55a80c0fd9b82771efaef5e7296abc4 1961 SMART SM00487 88 335 3.9E-16 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS07305 d55a80c0fd9b82771efaef5e7296abc4 1961 Pfam PF09369 Domain of unknown function (DUF1998) 1522 1600 8.5E-11 T 22-04-2016 IPR018973 DEAD/DEAH-box helicase, putative HRM2_RS07305 d55a80c0fd9b82771efaef5e7296abc4 1961 SUPERFAMILY SSF52540 219 303 1.98E-23 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08490 9d1bc48a7889eb972fff0faee29bfff7 75 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 65 3.5E-30 T 22-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS08490 9d1bc48a7889eb972fff0faee29bfff7 75 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 67 28.959 T 22-04-2016 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS08490 9d1bc48a7889eb972fff0faee29bfff7 75 SUPERFAMILY SSF143800 1 66 5.1E-26 T 22-04-2016 HRM2_RS08490 9d1bc48a7889eb972fff0faee29bfff7 75 PANTHER PTHR33280:SF2 1 71 5.4E-36 T 22-04-2016 HRM2_RS08490 9d1bc48a7889eb972fff0faee29bfff7 75 ProSitePatterns PS01143 Ribosomal protein L31 signature. 34 55 - T 22-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS08490 9d1bc48a7889eb972fff0faee29bfff7 75 PANTHER PTHR33280 1 71 5.4E-36 T 22-04-2016 HRM2_RS08490 9d1bc48a7889eb972fff0faee29bfff7 75 PRINTS PR01249 Ribosomal protein L31 signature 2 19 2.7E-23 T 22-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS08490 9d1bc48a7889eb972fff0faee29bfff7 75 PRINTS PR01249 Ribosomal protein L31 signature 45 63 2.7E-23 T 22-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS08490 9d1bc48a7889eb972fff0faee29bfff7 75 PRINTS PR01249 Ribosomal protein L31 signature 30 45 2.7E-23 T 22-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS08490 9d1bc48a7889eb972fff0faee29bfff7 75 Pfam PF01197 Ribosomal protein L31 1 64 2.0E-31 T 22-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS16505 8bfb5f75ee80ea8c4048aa67ef7ebccd 408 PANTHER PTHR10314:SF3 5 390 4.0E-188 T 22-04-2016 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 HRM2_RS16505 8bfb5f75ee80ea8c4048aa67ef7ebccd 408 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 1 390 45.986 T 22-04-2016 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 HRM2_RS16505 8bfb5f75ee80ea8c4048aa67ef7ebccd 408 Gene3D G3DSA:3.40.50.1100 98 175 5.1E-20 T 22-04-2016 HRM2_RS16505 8bfb5f75ee80ea8c4048aa67ef7ebccd 408 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 51 373 4.2E-44 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HRM2_RS16505 8bfb5f75ee80ea8c4048aa67ef7ebccd 408 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 5 388 2.3E-179 T 22-04-2016 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 HRM2_RS16505 8bfb5f75ee80ea8c4048aa67ef7ebccd 408 PANTHER PTHR10314 5 390 4.0E-188 T 22-04-2016 HRM2_RS16505 8bfb5f75ee80ea8c4048aa67ef7ebccd 408 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 79 93 - T 22-04-2016 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 HRM2_RS16505 8bfb5f75ee80ea8c4048aa67ef7ebccd 408 SUPERFAMILY SSF53686 4 388 5.24E-128 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HRM2_RS16505 8bfb5f75ee80ea8c4048aa67ef7ebccd 408 PIRSF PIRSF001413 2 395 1.6E-144 T 22-04-2016 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 HRM2_RS16505 8bfb5f75ee80ea8c4048aa67ef7ebccd 408 Gene3D G3DSA:3.40.50.1100 176 392 6.0E-80 T 22-04-2016 HRM2_RS00640 31d3243c2e82e5d10ee0a7129ec102e4 147 PANTHER PTHR33202 4 146 4.6E-43 T 22-04-2016 HRM2_RS00640 31d3243c2e82e5d10ee0a7129ec102e4 147 PANTHER PTHR33202:SF7 4 146 4.6E-43 T 22-04-2016 HRM2_RS00640 31d3243c2e82e5d10ee0a7129ec102e4 147 Gene3D G3DSA:1.10.10.10 9 89 2.1E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS00640 31d3243c2e82e5d10ee0a7129ec102e4 147 SUPERFAMILY SSF46785 10 141 7.62E-32 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS00640 31d3243c2e82e5d10ee0a7129ec102e4 147 Pfam PF01475 Ferric uptake regulator family 18 135 5.1E-32 T 22-04-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 HRM2_RS02260 50af0554408c20012d41a6833d817b03 173 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 3 173 27.264 T 22-04-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 HRM2_RS02260 50af0554408c20012d41a6833d817b03 173 PANTHER PTHR10938 1 173 2.0E-64 T 22-04-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 HRM2_RS02260 50af0554408c20012d41a6833d817b03 173 ProSitePatterns PS00938 Initiation factor 3 signature. 63 76 - T 22-04-2016 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 HRM2_RS02260 50af0554408c20012d41a6833d817b03 173 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 89 173 1.5E-34 T 22-04-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 HRM2_RS02260 50af0554408c20012d41a6833d817b03 173 SUPERFAMILY SSF55200 89 173 1.44E-29 T 22-04-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 HRM2_RS02260 50af0554408c20012d41a6833d817b03 173 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 12 81 7.9E-33 T 22-04-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 HRM2_RS02260 50af0554408c20012d41a6833d817b03 173 Gene3D G3DSA:3.10.20.80 8 83 5.4E-36 T 22-04-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 HRM2_RS02260 50af0554408c20012d41a6833d817b03 173 SUPERFAMILY SSF54364 11 83 5.75E-29 T 22-04-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 HRM2_RS02260 50af0554408c20012d41a6833d817b03 173 Gene3D G3DSA:3.30.110.10 84 173 2.4E-33 T 22-04-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 HRM2_RS02260 50af0554408c20012d41a6833d817b03 173 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 12 173 8.8E-64 T 22-04-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 HRM2_RS04240 27091e03689b3e32bb6ba292c883e7c8 326 SUPERFAMILY SSF51569 12 325 1.9E-94 T 22-04-2016 HRM2_RS04240 27091e03689b3e32bb6ba292c883e7c8 326 PIRSF PIRSF001359 10 326 1.4E-90 T 22-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 HRM2_RS04240 27091e03689b3e32bb6ba292c883e7c8 326 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 12 324 3.0E-84 T 22-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 HRM2_RS04240 27091e03689b3e32bb6ba292c883e7c8 326 Pfam PF01116 Fructose-bisphosphate aldolase class-II 13 325 2.4E-98 T 22-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 HRM2_RS04240 27091e03689b3e32bb6ba292c883e7c8 326 PANTHER PTHR30304 5 326 1.0E-112 T 22-04-2016 HRM2_RS04240 27091e03689b3e32bb6ba292c883e7c8 326 Gene3D G3DSA:3.20.20.70 12 326 2.9E-104 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS04240 27091e03689b3e32bb6ba292c883e7c8 326 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 12 325 9.3E-109 T 22-04-2016 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385|UniPathway: UPA00109 HRM2_RS07115 72ff610e5642120d89779e13371bba66 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 2.9E-13 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS07115 72ff610e5642120d89779e13371bba66 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 2.9E-13 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS07115 72ff610e5642120d89779e13371bba66 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 2.9E-13 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS07115 72ff610e5642120d89779e13371bba66 217 SMART SM00421 151 208 8.3E-24 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS07115 72ff610e5642120d89779e13371bba66 217 SUPERFAMILY SSF52172 4 132 5.98E-32 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS07115 72ff610e5642120d89779e13371bba66 217 PANTHER PTHR26402:SF583 4 210 3.1E-67 T 22-04-2016 HRM2_RS07115 72ff610e5642120d89779e13371bba66 217 SMART SM00448 4 117 3.9E-30 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS07115 72ff610e5642120d89779e13371bba66 217 SUPERFAMILY SSF46894 151 214 1.29E-21 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HRM2_RS07115 72ff610e5642120d89779e13371bba66 217 Gene3D G3DSA:3.40.50.2300 2 158 4.7E-35 T 22-04-2016 HRM2_RS07115 72ff610e5642120d89779e13371bba66 217 PANTHER PTHR26402 4 210 3.1E-67 T 22-04-2016 HRM2_RS07115 72ff610e5642120d89779e13371bba66 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS07115 72ff610e5642120d89779e13371bba66 217 Gene3D G3DSA:1.10.10.10 159 214 2.0E-24 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS07115 72ff610e5642120d89779e13371bba66 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 208 1.8E-20 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS07115 72ff610e5642120d89779e13371bba66 217 Pfam PF00072 Response regulator receiver domain 6 117 1.3E-27 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS11570 c580d68a508271c255c673055980b17b 477 SUPERFAMILY SSF47323 317 476 1.83E-34 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS11570 c580d68a508271c255c673055980b17b 477 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 17 313 2.7E-137 T 22-04-2016 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 HRM2_RS11570 c580d68a508271c255c673055980b17b 477 Gene3D G3DSA:1.20.120.640 308 404 6.6E-17 T 22-04-2016 HRM2_RS11570 c580d68a508271c255c673055980b17b 477 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 477 39.922 T 22-04-2016 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16|Reactome: REACT_71 HRM2_RS11570 c580d68a508271c255c673055980b17b 477 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 4.77E-31 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HRM2_RS11570 c580d68a508271c255c673055980b17b 477 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 223 244 4.77E-31 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HRM2_RS11570 c580d68a508271c255c673055980b17b 477 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 4.77E-31 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HRM2_RS11570 c580d68a508271c255c673055980b17b 477 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 192 210 4.77E-31 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HRM2_RS11570 c580d68a508271c255c673055980b17b 477 SMART SM00840 345 414 5.4E-17 T 22-04-2016 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 HRM2_RS11570 c580d68a508271c255c673055980b17b 477 SUPERFAMILY SSF52374 3 313 1.74E-103 T 22-04-2016 HRM2_RS11570 c580d68a508271c255c673055980b17b 477 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 475 5.1E-174 T 22-04-2016 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16|Reactome: REACT_71 HRM2_RS11570 c580d68a508271c255c673055980b17b 477 Pfam PF09190 DALR domain 346 413 7.3E-16 T 22-04-2016 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 HRM2_RS11570 c580d68a508271c255c673055980b17b 477 PANTHER PTHR10890 1 476 1.7E-248 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HRM2_RS11570 c580d68a508271c255c673055980b17b 477 Gene3D G3DSA:3.40.50.620 20 306 9.8E-117 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS02700 ad1c76aad69be79112b7a6a3ad0e8801 98 SUPERFAMILY SSF143430 4 82 1.83E-20 T 22-04-2016 HRM2_RS02700 ad1c76aad69be79112b7a6a3ad0e8801 98 Pfam PF09827 CRISPR associated protein Cas2 6 76 1.2E-17 T 22-04-2016 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 HRM2_RS02700 ad1c76aad69be79112b7a6a3ad0e8801 98 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 7 86 1.4E-13 T 22-04-2016 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 HRM2_RS02700 ad1c76aad69be79112b7a6a3ad0e8801 98 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 3 94 14.8 T 22-04-2016 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 HRM2_RS02700 ad1c76aad69be79112b7a6a3ad0e8801 98 Gene3D G3DSA:3.30.70.240 3 74 6.4E-24 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain HRM2_RS02700 ad1c76aad69be79112b7a6a3ad0e8801 98 PANTHER PTHR34405 1 94 1.1E-17 T 22-04-2016 HRM2_RS13385 b8f81a44afd6c720d54e68299de37953 151 SUPERFAMILY SSF52304 9 149 1.23E-57 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 HRM2_RS13385 b8f81a44afd6c720d54e68299de37953 151 ProSitePatterns PS01029 Dehydroquinase class II signature. 13 30 - T 22-04-2016 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 HRM2_RS13385 b8f81a44afd6c720d54e68299de37953 151 Pfam PF01220 Dehydroquinase class II 10 146 1.1E-55 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 HRM2_RS13385 b8f81a44afd6c720d54e68299de37953 151 Gene3D G3DSA:3.40.50.9100 9 149 1.5E-60 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 HRM2_RS13385 b8f81a44afd6c720d54e68299de37953 151 PIRSF PIRSF001399 6 151 7.2E-59 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 HRM2_RS13385 b8f81a44afd6c720d54e68299de37953 151 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 10 146 4.0E-40 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 HRM2_RS13385 b8f81a44afd6c720d54e68299de37953 151 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 10 148 1.1E-58 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 HRM2_RS13385 b8f81a44afd6c720d54e68299de37953 151 PANTHER PTHR21272 5 150 8.2E-77 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 HRM2_RS13385 b8f81a44afd6c720d54e68299de37953 151 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 151 64.108 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 HRM2_RS00180 6da23e29aa17cbd2232e61acc8f447d3 191 ProSitePatterns PS00398 Site-specific recombinases signature 2. 58 70 - T 22-04-2016 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 HRM2_RS00180 6da23e29aa17cbd2232e61acc8f447d3 191 Gene3D G3DSA:1.10.10.60 141 182 1.8E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS00180 6da23e29aa17cbd2232e61acc8f447d3 191 SMART SM00857 3 139 2.8E-44 T 22-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HRM2_RS00180 6da23e29aa17cbd2232e61acc8f447d3 191 SUPERFAMILY SSF46689 141 183 4.1E-6 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS00180 6da23e29aa17cbd2232e61acc8f447d3 191 SUPERFAMILY SSF53041 1 139 4.71E-37 T 22-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HRM2_RS00180 6da23e29aa17cbd2232e61acc8f447d3 191 PANTHER PTHR30461:SF9 1 184 6.3E-47 T 22-04-2016 HRM2_RS00180 6da23e29aa17cbd2232e61acc8f447d3 191 PANTHER PTHR30461 1 184 6.3E-47 T 22-04-2016 HRM2_RS00180 6da23e29aa17cbd2232e61acc8f447d3 191 Pfam PF00239 Resolvase, N terminal domain 4 139 2.4E-37 T 22-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HRM2_RS00180 6da23e29aa17cbd2232e61acc8f447d3 191 Gene3D G3DSA:3.40.50.1390 3 122 8.7E-32 T 22-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HRM2_RS12765 3a23a14a4fbe8ea7d21ea0a08481ef3a 75 Pfam PF02609 Exonuclease VII small subunit 7 57 1.1E-19 T 22-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 HRM2_RS12765 3a23a14a4fbe8ea7d21ea0a08481ef3a 75 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 6 66 14.553 T 22-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 HRM2_RS12765 3a23a14a4fbe8ea7d21ea0a08481ef3a 75 Gene3D G3DSA:1.10.287.1040 3 73 2.7E-24 T 22-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 HRM2_RS12765 3a23a14a4fbe8ea7d21ea0a08481ef3a 75 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 6 61 6.4E-21 T 22-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 HRM2_RS12765 3a23a14a4fbe8ea7d21ea0a08481ef3a 75 SUPERFAMILY SSF116842 3 70 5.89E-20 T 22-04-2016 HRM2_RS12765 3a23a14a4fbe8ea7d21ea0a08481ef3a 75 PIRSF PIRSF006488 1 75 2.9E-21 T 22-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 HRM2_RS12765 3a23a14a4fbe8ea7d21ea0a08481ef3a 75 PANTHER PTHR34137 1 63 8.6E-17 T 22-04-2016 HRM2_RS12765 3a23a14a4fbe8ea7d21ea0a08481ef3a 75 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 6 47 6.0E-7 T 22-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 HRM2_RS23425 5bcbe1608d1d15bf7abdd2f5b8c1d3f6 449 SUPERFAMILY SSF51726 1 333 1.83E-62 T 22-04-2016 HRM2_RS23425 5bcbe1608d1d15bf7abdd2f5b8c1d3f6 449 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 3 332 2.0E-56 T 22-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 HRM2_RS23425 5bcbe1608d1d15bf7abdd2f5b8c1d3f6 449 PANTHER PTHR21091 110 376 1.4E-13 T 22-04-2016 HRM2_RS23425 5bcbe1608d1d15bf7abdd2f5b8c1d3f6 449 Gene3D G3DSA:3.20.20.210 1 332 2.2E-62 T 22-04-2016 HRM2_RS23425 5bcbe1608d1d15bf7abdd2f5b8c1d3f6 449 Gene3D G3DSA:3.40.30.10 372 442 4.1E-10 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS23425 5bcbe1608d1d15bf7abdd2f5b8c1d3f6 449 PANTHER PTHR21091:SF2 110 376 1.4E-13 T 22-04-2016 HRM2_RS02655 1071458e23b9facf7718736e62130483 515 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 400 409 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS02655 1071458e23b9facf7718736e62130483 515 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 211 224 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS02655 1071458e23b9facf7718736e62130483 515 Gene3D G3DSA:3.40.50.300 185 359 1.5E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02655 1071458e23b9facf7718736e62130483 515 Pfam PF00158 Sigma-54 interaction domain 187 353 1.1E-66 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS02655 1071458e23b9facf7718736e62130483 515 SUPERFAMILY SSF55781 6 181 2.16E-15 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS02655 1071458e23b9facf7718736e62130483 515 SUPERFAMILY SSF46689 400 510 2.69E-8 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS02655 1071458e23b9facf7718736e62130483 515 Gene3D G3DSA:3.30.450.40 4 166 1.9E-15 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS02655 1071458e23b9facf7718736e62130483 515 Gene3D G3DSA:1.10.10.60 468 511 6.6E-5 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS02655 1071458e23b9facf7718736e62130483 515 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 273 288 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS02655 1071458e23b9facf7718736e62130483 515 PANTHER PTHR32071 136 510 6.0E-138 T 22-04-2016 HRM2_RS02655 1071458e23b9facf7718736e62130483 515 SUPERFAMILY SSF52540 186 429 1.03E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02655 1071458e23b9facf7718736e62130483 515 SMART SM00382 207 350 9.4E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS02655 1071458e23b9facf7718736e62130483 515 Gene3D G3DSA:1.10.8.60 360 434 1.2E-22 T 22-04-2016 HRM2_RS02095 e26729423d96e2a4a47bc26a1cadabd8 788 Pfam PF01228 Glycine radical 668 770 3.4E-31 T 22-04-2016 IPR001150 Glycine radical domain GO:0003824|GO:0008152 HRM2_RS02095 e26729423d96e2a4a47bc26a1cadabd8 788 PANTHER PTHR30191:SF6 1 788 1.0E-295 T 22-04-2016 HRM2_RS02095 e26729423d96e2a4a47bc26a1cadabd8 788 PANTHER PTHR30191 1 788 1.0E-295 T 22-04-2016 HRM2_RS02095 e26729423d96e2a4a47bc26a1cadabd8 788 Pfam PF02901 Pyruvate formate lyase-like 5 651 1.0E-201 T 22-04-2016 IPR004184 Pyruvate formate lyase domain GO:0003824 HRM2_RS02095 e26729423d96e2a4a47bc26a1cadabd8 788 Gene3D G3DSA:3.20.70.20 3 787 2.2E-234 T 22-04-2016 HRM2_RS02095 e26729423d96e2a4a47bc26a1cadabd8 788 SUPERFAMILY SSF51998 4 787 2.29E-211 T 22-04-2016 HRM2_RS13615 aef487bd83b3d16f4ee726640365867a 215 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 211 1.3E-98 T 22-04-2016 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 HRM2_RS13615 aef487bd83b3d16f4ee726640365867a 215 Gene3D G3DSA:3.20.20.70 1 213 7.5E-77 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS13615 aef487bd83b3d16f4ee726640365867a 215 ProSitePatterns PS00958 Transaldolase active site. 80 97 - T 22-04-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 HRM2_RS13615 aef487bd83b3d16f4ee726640365867a 215 Hamap MF_00494 Probable transaldolase [tal]. 1 214 47.874 T 22-04-2016 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 HRM2_RS13615 aef487bd83b3d16f4ee726640365867a 215 PANTHER PTHR10683 1 215 5.9E-90 T 22-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 HRM2_RS13615 aef487bd83b3d16f4ee726640365867a 215 Pfam PF00923 Transaldolase 3 208 5.0E-62 T 22-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 HRM2_RS13615 aef487bd83b3d16f4ee726640365867a 215 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 22-04-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 HRM2_RS13615 aef487bd83b3d16f4ee726640365867a 215 SUPERFAMILY SSF51569 1 213 8.58E-81 T 22-04-2016 HRM2_RS13815 74d4d31a510391ca3c14576fb1a10088 137 Pfam PF03610 PTS system fructose IIA component 3 116 2.3E-24 T 22-04-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 HRM2_RS13815 74d4d31a510391ca3c14576fb1a10088 137 PANTHER PTHR33799 2 131 6.0E-33 T 22-04-2016 HRM2_RS13815 74d4d31a510391ca3c14576fb1a10088 137 Gene3D G3DSA:3.40.50.510 1 130 1.5E-34 T 22-04-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 HRM2_RS13815 74d4d31a510391ca3c14576fb1a10088 137 SUPERFAMILY SSF53062 1 129 2.09E-30 T 22-04-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 HRM2_RS15430 0be6aa36e56e3eb62aca6ddd4975087b 401 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 7 198 2.5E-83 T 22-04-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 HRM2_RS15430 0be6aa36e56e3eb62aca6ddd4975087b 401 PIRSF PIRSF001259 1 401 5.3E-180 T 22-04-2016 HRM2_RS15430 0be6aa36e56e3eb62aca6ddd4975087b 401 Gene3D G3DSA:3.90.870.10 5 210 8.1E-97 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain HRM2_RS15430 0be6aa36e56e3eb62aca6ddd4975087b 401 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 203 39.842 T 22-04-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 HRM2_RS15430 0be6aa36e56e3eb62aca6ddd4975087b 401 SUPERFAMILY SSF55821 3 203 3.43E-86 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain HRM2_RS15430 0be6aa36e56e3eb62aca6ddd4975087b 401 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 5 199 7.5E-76 T 22-04-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 HRM2_RS15430 0be6aa36e56e3eb62aca6ddd4975087b 401 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 204 400 39.433 T 22-04-2016 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 HRM2_RS15430 0be6aa36e56e3eb62aca6ddd4975087b 401 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 209 398 4.4E-79 T 22-04-2016 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 HRM2_RS15430 0be6aa36e56e3eb62aca6ddd4975087b 401 Pfam PF00925 GTP cyclohydrolase II 208 374 9.6E-74 T 22-04-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 HRM2_RS15430 0be6aa36e56e3eb62aca6ddd4975087b 401 PANTHER PTHR21327 5 398 1.9E-233 T 22-04-2016 HRM2_RS15430 0be6aa36e56e3eb62aca6ddd4975087b 401 SUPERFAMILY SSF142695 205 377 3.4E-72 T 22-04-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 HRM2_RS15430 0be6aa36e56e3eb62aca6ddd4975087b 401 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 2 396 51.542 T 22-04-2016 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275|UniPathway: UPA00275 HRM2_RS19605 c5568a79bcb6b0fb1a5932d85ce0ea4a 1076 Gene3D G3DSA:2.10.109.10 927 1071 1.1E-12 T 22-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain HRM2_RS19605 c5568a79bcb6b0fb1a5932d85ce0ea4a 1076 PANTHER PTHR24031 395 532 8.7E-32 T 22-04-2016 HRM2_RS19605 c5568a79bcb6b0fb1a5932d85ce0ea4a 1076 PANTHER PTHR24031 198 344 8.7E-32 T 22-04-2016 HRM2_RS19605 c5568a79bcb6b0fb1a5932d85ce0ea4a 1076 Gene3D G3DSA:3.40.50.300 194 347 1.8E-25 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19605 c5568a79bcb6b0fb1a5932d85ce0ea4a 1076 SUPERFAMILY SSF56024 15 160 1.48E-10 T 22-04-2016 HRM2_RS19605 c5568a79bcb6b0fb1a5932d85ce0ea4a 1076 SUPERFAMILY SSF52540 242 383 9.37E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19605 c5568a79bcb6b0fb1a5932d85ce0ea4a 1076 SUPERFAMILY SSF52540 411 533 9.37E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19605 c5568a79bcb6b0fb1a5932d85ce0ea4a 1076 Pfam PF04851 Type III restriction enzyme, res subunit 196 343 2.5E-32 T 22-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HRM2_RS19605 c5568a79bcb6b0fb1a5932d85ce0ea4a 1076 Gene3D G3DSA:3.30.870.10 16 162 7.0E-10 T 22-04-2016 HRM2_RS19605 c5568a79bcb6b0fb1a5932d85ce0ea4a 1076 Pfam PF13091 PLD-like domain 23 142 2.5E-11 T 22-04-2016 IPR025202 Phospholipase D-like domain HRM2_RS19605 c5568a79bcb6b0fb1a5932d85ce0ea4a 1076 SMART SM00490 438 518 6.2E-13 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS19605 c5568a79bcb6b0fb1a5932d85ce0ea4a 1076 PANTHER PTHR24031:SF311 395 532 8.7E-32 T 22-04-2016 HRM2_RS19605 c5568a79bcb6b0fb1a5932d85ce0ea4a 1076 PANTHER PTHR24031:SF311 198 344 8.7E-32 T 22-04-2016 HRM2_RS19605 c5568a79bcb6b0fb1a5932d85ce0ea4a 1076 SUPERFAMILY SSF51306 926 1070 1.45E-11 T 22-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C HRM2_RS19605 c5568a79bcb6b0fb1a5932d85ce0ea4a 1076 SMART SM00487 192 378 3.0E-19 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS19605 c5568a79bcb6b0fb1a5932d85ce0ea4a 1076 Pfam PF00271 Helicase conserved C-terminal domain 420 517 2.3E-10 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS19605 c5568a79bcb6b0fb1a5932d85ce0ea4a 1076 Gene3D G3DSA:3.40.50.300 411 533 6.1E-20 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14285 bc2a428b8dcab516ebe6391335214d0d 227 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 31 200 2.0E-6 T 22-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 HRM2_RS14285 bc2a428b8dcab516ebe6391335214d0d 227 Gene3D G3DSA:3.40.50.1240 137 224 1.6E-7 T 22-04-2016 IPR029033 Histidine phosphatase superfamily HRM2_RS14285 bc2a428b8dcab516ebe6391335214d0d 227 Gene3D G3DSA:3.40.50.1240 29 100 1.6E-7 T 22-04-2016 IPR029033 Histidine phosphatase superfamily HRM2_RS14285 bc2a428b8dcab516ebe6391335214d0d 227 SUPERFAMILY SSF53254 30 200 1.96E-13 T 22-04-2016 IPR029033 Histidine phosphatase superfamily HRM2_RS03780 5d01a17789e964cbf447ad7201d5d63d 197 SUPERFAMILY SSF46689 12 83 4.77E-15 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS03780 5d01a17789e964cbf447ad7201d5d63d 197 Pfam PF08359 YsiA-like protein, C-terminal region 67 192 8.5E-11 T 22-04-2016 IPR013570 Transcription regulator YsiA, C-terminal HRM2_RS03780 5d01a17789e964cbf447ad7201d5d63d 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 2.7E-12 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS03780 5d01a17789e964cbf447ad7201d5d63d 197 Gene3D G3DSA:1.10.10.60 12 61 5.1E-16 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS03780 5d01a17789e964cbf447ad7201d5d63d 197 PANTHER PTHR30055 12 195 3.1E-26 T 22-04-2016 HRM2_RS03780 5d01a17789e964cbf447ad7201d5d63d 197 SUPERFAMILY SSF48498 83 196 6.02E-22 T 22-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal HRM2_RS03780 5d01a17789e964cbf447ad7201d5d63d 197 Gene3D G3DSA:1.10.357.10 62 197 3.2E-31 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HRM2_RS03780 5d01a17789e964cbf447ad7201d5d63d 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.7E-7 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS03780 5d01a17789e964cbf447ad7201d5d63d 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.7E-7 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS12560 15116f1b55ee1b9ad6cb091a58d9d243 236 SUPERFAMILY SSF53448 2 233 1.57E-58 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS12560 15116f1b55ee1b9ad6cb091a58d9d243 236 Gene3D G3DSA:3.90.550.10 4 208 1.4E-39 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS12560 15116f1b55ee1b9ad6cb091a58d9d243 236 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 1 232 2.7E-113 T 22-04-2016 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 HRM2_RS12560 15116f1b55ee1b9ad6cb091a58d9d243 236 Pfam PF00483 Nucleotidyl transferase 6 183 3.7E-42 T 22-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 HRM2_RS12560 15116f1b55ee1b9ad6cb091a58d9d243 236 PANTHER PTHR22572:SF105 1 213 1.4E-118 T 22-04-2016 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 HRM2_RS12560 15116f1b55ee1b9ad6cb091a58d9d243 236 PANTHER PTHR22572 1 213 1.4E-118 T 22-04-2016 HRM2_RS15205 a04c76b5f9af034d04ed14e78c5b3d36 495 SUPERFAMILY SSF55874 324 485 1.57E-40 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS15205 a04c76b5f9af034d04ed14e78c5b3d36 495 SMART SM00091 130 197 9.8E-7 T 22-04-2016 IPR000014 PAS domain HRM2_RS15205 a04c76b5f9af034d04ed14e78c5b3d36 495 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 128 253 5.8E-17 T 22-04-2016 IPR000014 PAS domain HRM2_RS15205 a04c76b5f9af034d04ed14e78c5b3d36 495 Gene3D G3DSA:1.10.287.130 263 319 6.6E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS15205 a04c76b5f9af034d04ed14e78c5b3d36 495 Gene3D G3DSA:3.30.565.10 320 485 9.3E-40 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS15205 a04c76b5f9af034d04ed14e78c5b3d36 495 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 377 485 2.6E-20 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS15205 a04c76b5f9af034d04ed14e78c5b3d36 495 PANTHER PTHR24423 122 487 4.6E-83 T 22-04-2016 HRM2_RS15205 a04c76b5f9af034d04ed14e78c5b3d36 495 SUPERFAMILY SSF47384 257 333 5.69E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS15205 a04c76b5f9af034d04ed14e78c5b3d36 495 SMART SM00387 376 486 3.4E-32 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS15205 a04c76b5f9af034d04ed14e78c5b3d36 495 Pfam PF00512 His Kinase A (phospho-acceptor) domain 268 332 1.1E-15 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS15205 a04c76b5f9af034d04ed14e78c5b3d36 495 SUPERFAMILY SSF55785 141 255 3.32E-18 T 22-04-2016 IPR000014 PAS domain HRM2_RS15205 a04c76b5f9af034d04ed14e78c5b3d36 495 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 464 2.7E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS15205 a04c76b5f9af034d04ed14e78c5b3d36 495 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 429 2.7E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS15205 a04c76b5f9af034d04ed14e78c5b3d36 495 PRINTS PR00344 Bacterial sensor protein C-terminal signature 470 483 2.7E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS15205 a04c76b5f9af034d04ed14e78c5b3d36 495 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 443 2.7E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS15205 a04c76b5f9af034d04ed14e78c5b3d36 495 Gene3D G3DSA:3.30.450.20 127 244 7.3E-18 T 22-04-2016 HRM2_RS15205 a04c76b5f9af034d04ed14e78c5b3d36 495 SMART SM00388 268 334 9.5E-17 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS15205 a04c76b5f9af034d04ed14e78c5b3d36 495 Pfam PF00989 PAS fold 131 242 2.2E-12 T 22-04-2016 IPR013767 PAS fold GO:0006355 HRM2_RS09445 98da61a4869be9ddff664bf2ddc81e15 279 Gene3D G3DSA:3.30.70.20 156 249 6.9E-40 T 22-04-2016 HRM2_RS09445 98da61a4869be9ddff664bf2ddc81e15 279 Gene3D G3DSA:3.30.70.20 10 66 6.9E-40 T 22-04-2016 HRM2_RS09445 98da61a4869be9ddff664bf2ddc81e15 279 PANTHER PTHR11938:SF86 187 218 1.2E-38 T 22-04-2016 HRM2_RS09445 98da61a4869be9ddff664bf2ddc81e15 279 PANTHER PTHR11938:SF86 63 134 1.2E-38 T 22-04-2016 HRM2_RS09445 98da61a4869be9ddff664bf2ddc81e15 279 PANTHER PTHR11938:SF86 152 170 1.2E-38 T 22-04-2016 HRM2_RS09445 98da61a4869be9ddff664bf2ddc81e15 279 PANTHER PTHR11938:SF86 10 46 1.2E-38 T 22-04-2016 HRM2_RS09445 98da61a4869be9ddff664bf2ddc81e15 279 Gene3D G3DSA:3.30.70.20 124 144 3.6E-7 T 22-04-2016 HRM2_RS09445 98da61a4869be9ddff664bf2ddc81e15 279 Pfam PF12838 4Fe-4S dicluster domain 114 201 3.0E-9 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS09445 98da61a4869be9ddff664bf2ddc81e15 279 Gene3D G3DSA:3.30.70.20 67 123 2.9E-16 T 22-04-2016 HRM2_RS09445 98da61a4869be9ddff664bf2ddc81e15 279 SUPERFAMILY SSF54862 10 252 4.4E-48 T 22-04-2016 HRM2_RS09445 98da61a4869be9ddff664bf2ddc81e15 279 PANTHER PTHR11938 187 218 1.2E-38 T 22-04-2016 HRM2_RS09445 98da61a4869be9ddff664bf2ddc81e15 279 PANTHER PTHR11938 63 134 1.2E-38 T 22-04-2016 HRM2_RS09445 98da61a4869be9ddff664bf2ddc81e15 279 PANTHER PTHR11938 152 170 1.2E-38 T 22-04-2016 HRM2_RS09445 98da61a4869be9ddff664bf2ddc81e15 279 PANTHER PTHR11938 10 46 1.2E-38 T 22-04-2016 HRM2_RS09445 98da61a4869be9ddff664bf2ddc81e15 279 Pfam PF00037 4Fe-4S binding domain 15 31 6.9E-5 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS09445 98da61a4869be9ddff664bf2ddc81e15 279 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 115 126 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS19250 2b611b72ec514ab3d74c785184cf2952 71 Pfam PF00270 DEAD/DEAH box helicase 2 60 4.0E-14 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HRM2_RS19250 2b611b72ec514ab3d74c785184cf2952 71 SUPERFAMILY SSF52540 1 60 2.18E-17 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19250 2b611b72ec514ab3d74c785184cf2952 71 Gene3D G3DSA:3.40.50.300 1 58 1.9E-20 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19250 2b611b72ec514ab3d74c785184cf2952 71 PANTHER PTHR24031:SF180 1 58 1.0E-29 T 22-04-2016 HRM2_RS19250 2b611b72ec514ab3d74c785184cf2952 71 PANTHER PTHR24031 1 58 1.0E-29 T 22-04-2016 HRM2_RS20930 141d942fffc0a60c563334982cff3e29 118 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 11 97 4.9E-19 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS20930 141d942fffc0a60c563334982cff3e29 118 SUPERFAMILY SSF53146 1 112 1.02E-26 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS20930 141d942fffc0a60c563334982cff3e29 118 PANTHER PTHR33937 1 108 1.7E-23 T 22-04-2016 HRM2_RS20930 141d942fffc0a60c563334982cff3e29 118 PANTHER PTHR33937:SF3 1 108 1.7E-23 T 22-04-2016 HRM2_RS20930 141d942fffc0a60c563334982cff3e29 118 Gene3D G3DSA:3.30.420.130 1 98 4.3E-28 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS18975 9e99da46aa0daa1fc5c26386b51a575f 556 PANTHER PTHR10617 1 478 1.0E-135 T 22-04-2016 HRM2_RS18975 9e99da46aa0daa1fc5c26386b51a575f 556 SUPERFAMILY SSF54862 456 554 2.2E-25 T 22-04-2016 HRM2_RS18975 9e99da46aa0daa1fc5c26386b51a575f 556 PANTHER PTHR10617:SF107 1 478 1.0E-135 T 22-04-2016 IPR007859 ETF-QO/FixX GO:0051536|GO:0055114 HRM2_RS18975 9e99da46aa0daa1fc5c26386b51a575f 556 Gene3D G3DSA:3.50.50.60 3 367 2.4E-22 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS18975 9e99da46aa0daa1fc5c26386b51a575f 556 SUPERFAMILY SSF51905 6 210 5.93E-35 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS18975 9e99da46aa0daa1fc5c26386b51a575f 556 SUPERFAMILY SSF51905 310 394 5.93E-35 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS18975 9e99da46aa0daa1fc5c26386b51a575f 556 Gene3D G3DSA:3.30.70.20 477 534 5.7E-6 T 22-04-2016 HRM2_RS18975 9e99da46aa0daa1fc5c26386b51a575f 556 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 452 554 4.1E-41 T 22-04-2016 IPR007859 ETF-QO/FixX GO:0051536|GO:0055114 HRM2_RS18975 9e99da46aa0daa1fc5c26386b51a575f 556 SUPERFAMILY SSF54373 212 309 4.32E-20 T 22-04-2016 HRM2_RS03660 c06a2ca5472c3b6cc05ef89a321cc5fc 498 PANTHER PTHR32071:SF26 149 498 2.8E-129 T 22-04-2016 HRM2_RS03660 c06a2ca5472c3b6cc05ef89a321cc5fc 498 Gene3D G3DSA:1.10.8.60 333 397 7.3E-17 T 22-04-2016 HRM2_RS03660 c06a2ca5472c3b6cc05ef89a321cc5fc 498 Gene3D G3DSA:3.40.50.300 153 326 1.8E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03660 c06a2ca5472c3b6cc05ef89a321cc5fc 498 SUPERFAMILY SSF46689 435 487 1.03E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS03660 c06a2ca5472c3b6cc05ef89a321cc5fc 498 SUPERFAMILY SSF46689 368 403 1.03E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS03660 c06a2ca5472c3b6cc05ef89a321cc5fc 498 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 451 468 1.1E-9 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS03660 c06a2ca5472c3b6cc05ef89a321cc5fc 498 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 468 488 1.1E-9 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS03660 c06a2ca5472c3b6cc05ef89a321cc5fc 498 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 368 377 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS03660 c06a2ca5472c3b6cc05ef89a321cc5fc 498 Pfam PF00158 Sigma-54 interaction domain 156 321 5.8E-61 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS03660 c06a2ca5472c3b6cc05ef89a321cc5fc 498 Pfam PF00989 PAS fold 22 125 6.6E-5 T 22-04-2016 IPR013767 PAS fold GO:0006355 HRM2_RS03660 c06a2ca5472c3b6cc05ef89a321cc5fc 498 SUPERFAMILY SSF55785 22 122 4.54E-12 T 22-04-2016 IPR000014 PAS domain HRM2_RS03660 c06a2ca5472c3b6cc05ef89a321cc5fc 498 SMART SM00382 176 318 1.0E-6 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS03660 c06a2ca5472c3b6cc05ef89a321cc5fc 498 PANTHER PTHR32071 149 498 2.8E-129 T 22-04-2016 HRM2_RS03660 c06a2ca5472c3b6cc05ef89a321cc5fc 498 SUPERFAMILY SSF52540 155 389 3.42E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03660 c06a2ca5472c3b6cc05ef89a321cc5fc 498 Gene3D G3DSA:3.30.450.20 22 67 9.6E-9 T 22-04-2016 HRM2_RS03660 c06a2ca5472c3b6cc05ef89a321cc5fc 498 Gene3D G3DSA:1.10.10.60 443 486 3.3E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS03660 c06a2ca5472c3b6cc05ef89a321cc5fc 498 Pfam PF02954 Bacterial regulatory protein, Fis family 447 485 1.5E-10 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS03660 c06a2ca5472c3b6cc05ef89a321cc5fc 498 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 180 193 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS17485 1f5483686ed40b35608018d668e0b0fd 110 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 8 100 1.9E-20 T 22-04-2016 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 HRM2_RS17485 1f5483686ed40b35608018d668e0b0fd 110 Pfam PF03334 Na+/H+ antiporter subunit 8 91 2.0E-24 T 22-04-2016 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 HRM2_RS17485 1f5483686ed40b35608018d668e0b0fd 110 PANTHER PTHR34703:SF1 1 88 1.3E-18 T 22-04-2016 HRM2_RS17485 1f5483686ed40b35608018d668e0b0fd 110 PANTHER PTHR34703 1 88 1.3E-18 T 22-04-2016 HRM2_RS04150 542e713a72c8386b5de5856f5b77bdc6 190 PANTHER PTHR10245 3 183 2.1E-36 T 22-04-2016 HRM2_RS04150 542e713a72c8386b5de5856f5b77bdc6 190 SUPERFAMILY SSF51182 81 182 1.49E-24 T 22-04-2016 IPR011051 RmlC-like cupin domain HRM2_RS04150 542e713a72c8386b5de5856f5b77bdc6 190 Pfam PF07883 Cupin domain 125 181 1.7E-12 T 22-04-2016 IPR013096 Cupin 2, conserved barrel HRM2_RS04150 542e713a72c8386b5de5856f5b77bdc6 190 PANTHER PTHR10245:SF9 3 183 2.1E-36 T 22-04-2016 HRM2_RS04150 542e713a72c8386b5de5856f5b77bdc6 190 Gene3D G3DSA:2.60.120.10 108 184 7.2E-22 T 22-04-2016 IPR014710 RmlC-like jelly roll fold HRM2_RS04150 542e713a72c8386b5de5856f5b77bdc6 190 Gene3D G3DSA:1.10.260.40 6 107 2.7E-21 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS04150 542e713a72c8386b5de5856f5b77bdc6 190 Pfam PF01381 Helix-turn-helix 10 62 3.2E-12 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS04150 542e713a72c8386b5de5856f5b77bdc6 190 SUPERFAMILY SSF47413 3 66 4.83E-15 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS04150 542e713a72c8386b5de5856f5b77bdc6 190 SMART SM00530 9 64 1.7E-12 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS05195 e27a9bb8729d15ee8c928ab61dd2a09e 256 Pfam PF13189 Cytidylate kinase-like family 63 233 8.5E-34 T 22-04-2016 IPR026865 Cytidylate kinase-like family MetaCyc: PWY-7205 HRM2_RS05195 e27a9bb8729d15ee8c928ab61dd2a09e 256 Gene3D G3DSA:3.40.50.300 63 248 1.1E-37 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10635 8a310bc13a03766382e1895dbeedac4c 431 SUPERFAMILY SSF56801 19 415 2.09E-52 T 22-04-2016 HRM2_RS10635 8a310bc13a03766382e1895dbeedac4c 431 Pfam PF14535 AMP-binding enzyme C-terminal domain 333 426 5.9E-23 T 22-04-2016 IPR028154 AMP-dependent ligase, C-terminal HRM2_RS10635 8a310bc13a03766382e1895dbeedac4c 431 PANTHER PTHR36932 10 428 1.4E-95 T 22-04-2016 HRM2_RS10635 8a310bc13a03766382e1895dbeedac4c 431 Pfam PF00501 AMP-binding enzyme 67 284 2.4E-13 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS10635 8a310bc13a03766382e1895dbeedac4c 431 Gene3D G3DSA:3.30.300.30 322 427 1.1E-27 T 22-04-2016 HRM2_RS10635 8a310bc13a03766382e1895dbeedac4c 431 Gene3D G3DSA:3.40.50.980 82 238 1.4E-9 T 22-04-2016 HRM2_RS10635 8a310bc13a03766382e1895dbeedac4c 431 PANTHER PTHR36932:SF1 10 428 1.4E-95 T 22-04-2016 HRM2_RS19145 1c6e5dba76306233740b561548c6abb2 249 Pfam PF02195 ParB-like nuclease domain 29 89 1.9E-5 T 22-04-2016 IPR003115 ParB/Sulfiredoxin HRM2_RS19145 1c6e5dba76306233740b561548c6abb2 249 SMART SM00470 7 100 0.0037 T 22-04-2016 IPR003115 ParB/Sulfiredoxin HRM2_RS19145 1c6e5dba76306233740b561548c6abb2 249 SUPERFAMILY SSF110849 28 107 3.66E-13 T 22-04-2016 IPR003115 ParB/Sulfiredoxin HRM2_RS19145 1c6e5dba76306233740b561548c6abb2 249 Gene3D G3DSA:3.90.1530.10 29 89 9.1E-9 T 22-04-2016 HRM2_RS06745 de06cebfd9c5ad9d957a462104933786 347 PANTHER PTHR10520 5 345 5.1E-187 T 22-04-2016 HRM2_RS06745 de06cebfd9c5ad9d957a462104933786 347 Gene3D G3DSA:3.30.1330.10 20 169 8.8E-59 T 22-04-2016 IPR016188 PurM-like, N-terminal domain HRM2_RS06745 de06cebfd9c5ad9d957a462104933786 347 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 5 335 7.3E-131 T 22-04-2016 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 HRM2_RS06745 de06cebfd9c5ad9d957a462104933786 347 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 5 344 44.291 T 22-04-2016 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 HRM2_RS06745 de06cebfd9c5ad9d957a462104933786 347 SUPERFAMILY SSF55326 4 169 7.33E-49 T 22-04-2016 HRM2_RS06745 de06cebfd9c5ad9d957a462104933786 347 Gene3D G3DSA:3.90.650.10 170 344 1.8E-62 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain HRM2_RS06745 de06cebfd9c5ad9d957a462104933786 347 Pfam PF00586 AIR synthase related protein, N-terminal domain 62 162 5.6E-16 T 22-04-2016 IPR016188 PurM-like, N-terminal domain HRM2_RS06745 de06cebfd9c5ad9d957a462104933786 347 SUPERFAMILY SSF56042 170 342 2.79E-54 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain HRM2_RS06745 de06cebfd9c5ad9d957a462104933786 347 Pfam PF02769 AIR synthase related protein, C-terminal domain 176 343 8.5E-26 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain HRM2_RS09765 7718c6812c5529aa5387b1d0f374afd5 464 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 20 463 4.8E-117 T 22-04-2016 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase HRM2_RS09765 7718c6812c5529aa5387b1d0f374afd5 464 PANTHER PTHR30576 18 464 4.1E-106 T 22-04-2016 HRM2_RS09765 7718c6812c5529aa5387b1d0f374afd5 464 PANTHER PTHR30576:SF0 18 464 4.1E-106 T 22-04-2016 HRM2_RS09765 7718c6812c5529aa5387b1d0f374afd5 464 TIGRFAM TIGR03013 EpsB_2: sugar transferase, PEP-CTERM system associated 22 464 7.7E-142 T 22-04-2016 IPR017464 Sugar transferase, PEP-CTERM system associated HRM2_RS09765 7718c6812c5529aa5387b1d0f374afd5 464 Pfam PF02397 Bacterial sugar transferase 275 458 6.7E-55 T 22-04-2016 IPR003362 Bacterial sugar transferase HRM2_RS19480 cd6d69d0650ab87e2e70ebbc42a82a12 253 PANTHER PTHR30050 8 243 7.1E-54 T 22-04-2016 HRM2_RS19480 cd6d69d0650ab87e2e70ebbc42a82a12 253 Gene3D G3DSA:3.40.50.300 91 231 1.8E-27 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19480 cd6d69d0650ab87e2e70ebbc42a82a12 253 Pfam PF01695 IstB-like ATP binding protein 58 233 3.9E-60 T 22-04-2016 IPR002611 IstB-like ATP-binding protein GO:0005524 HRM2_RS19480 cd6d69d0650ab87e2e70ebbc42a82a12 253 SMART SM00382 101 236 5.4E-6 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS19480 cd6d69d0650ab87e2e70ebbc42a82a12 253 PANTHER PTHR30050:SF6 8 243 7.1E-54 T 22-04-2016 HRM2_RS19480 cd6d69d0650ab87e2e70ebbc42a82a12 253 PIRSF PIRSF003073 4 251 5.9E-80 T 22-04-2016 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein HRM2_RS19480 cd6d69d0650ab87e2e70ebbc42a82a12 253 SUPERFAMILY SSF52540 97 231 8.79E-25 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10925 dddaf82b5f2e11dd1ac4bc7b591caf3d 351 SUPERFAMILY SSF46548 238 346 1.36E-14 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS10925 dddaf82b5f2e11dd1ac4bc7b591caf3d 351 PANTHER PTHR40447 2 351 1.4E-63 T 22-04-2016 HRM2_RS10925 dddaf82b5f2e11dd1ac4bc7b591caf3d 351 Gene3D G3DSA:1.10.1060.10 239 346 4.8E-15 T 22-04-2016 HRM2_RS10925 dddaf82b5f2e11dd1ac4bc7b591caf3d 351 Pfam PF17179 4Fe-4S dicluster domain 241 335 1.5E-32 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS10925 dddaf82b5f2e11dd1ac4bc7b591caf3d 351 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 321 332 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS10925 dddaf82b5f2e11dd1ac4bc7b591caf3d 351 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 242 253 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS13170 fcf8ebd7e41470020a799e2ff3d60c3a 462 Gene3D G3DSA:2.40.50.140 1 79 5.3E-24 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS13170 fcf8ebd7e41470020a799e2ff3d60c3a 462 SUPERFAMILY SSF53335 68 460 7.09E-78 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS13170 fcf8ebd7e41470020a799e2ff3d60c3a 462 PANTHER PTHR11061:SF30 3 460 4.7E-171 T 22-04-2016 HRM2_RS13170 fcf8ebd7e41470020a799e2ff3d60c3a 462 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 271 371 5.0E-9 T 22-04-2016 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 HRM2_RS13170 fcf8ebd7e41470020a799e2ff3d60c3a 462 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 386 460 3.5E-15 T 22-04-2016 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 HRM2_RS13170 fcf8ebd7e41470020a799e2ff3d60c3a 462 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 17 454 6.7E-109 T 22-04-2016 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 HRM2_RS13170 fcf8ebd7e41470020a799e2ff3d60c3a 462 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 393 424 - T 22-04-2016 IPR030390 RNA methyltransferase TrmA, active site HRM2_RS13170 fcf8ebd7e41470020a799e2ff3d60c3a 462 SUPERFAMILY SSF50249 3 59 3.94E-13 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS13170 fcf8ebd7e41470020a799e2ff3d60c3a 462 PANTHER PTHR11061 3 460 4.7E-171 T 22-04-2016 HRM2_RS13170 fcf8ebd7e41470020a799e2ff3d60c3a 462 Gene3D G3DSA:3.40.50.150 263 460 9.3E-69 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS13170 fcf8ebd7e41470020a799e2ff3d60c3a 462 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 444 454 - T 22-04-2016 IPR030391 RNA methyltransferase TrmA, conserved site HRM2_RS11145 2a8eb5674d3ec448bacd9dfe7abf4bb9 271 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 6 266 34.004 T 22-04-2016 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS11145 2a8eb5674d3ec448bacd9dfe7abf4bb9 271 SUPERFAMILY SSF51735 104 268 1.47E-42 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS11145 2a8eb5674d3ec448bacd9dfe7abf4bb9 271 PANTHER PTHR21089 1 271 2.5E-105 T 22-04-2016 HRM2_RS11145 2a8eb5674d3ec448bacd9dfe7abf4bb9 271 Gene3D G3DSA:3.40.192.10 2 107 5.4E-40 T 22-04-2016 HRM2_RS11145 2a8eb5674d3ec448bacd9dfe7abf4bb9 271 SUPERFAMILY SSF53223 2 103 1.15E-33 T 22-04-2016 HRM2_RS11145 2a8eb5674d3ec448bacd9dfe7abf4bb9 271 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 11 91 6.5E-28 T 22-04-2016 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS11145 2a8eb5674d3ec448bacd9dfe7abf4bb9 271 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 117 186 8.3E-6 T 22-04-2016 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase HRM2_RS11145 2a8eb5674d3ec448bacd9dfe7abf4bb9 271 Gene3D G3DSA:3.40.50.720 108 269 1.3E-52 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS11145 2a8eb5674d3ec448bacd9dfe7abf4bb9 271 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 8 268 4.1E-80 T 22-04-2016 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS14575 f83f81ba3e19dbf4ed296f8d9b4db2d8 598 SMART SM00028 423 456 1.3E-5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS14575 f83f81ba3e19dbf4ed296f8d9b4db2d8 598 SMART SM00028 353 386 240.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS14575 f83f81ba3e19dbf4ed296f8d9b4db2d8 598 SMART SM00028 387 420 0.31 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS14575 f83f81ba3e19dbf4ed296f8d9b4db2d8 598 SUPERFAMILY SSF48452 355 476 8.65E-23 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS14575 f83f81ba3e19dbf4ed296f8d9b4db2d8 598 Pfam PF13432 Tetratricopeptide repeat 362 414 2.6E-8 T 22-04-2016 HRM2_RS14575 f83f81ba3e19dbf4ed296f8d9b4db2d8 598 PANTHER PTHR22550 1 338 4.8E-61 T 22-04-2016 HRM2_RS14575 f83f81ba3e19dbf4ed296f8d9b4db2d8 598 Gene3D G3DSA:1.25.40.10 352 473 2.6E-23 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS14575 f83f81ba3e19dbf4ed296f8d9b4db2d8 598 PANTHER PTHR22550:SF8 1 338 4.8E-61 T 22-04-2016 HRM2_RS14575 f83f81ba3e19dbf4ed296f8d9b4db2d8 598 Pfam PF00092 von Willebrand factor type A domain 90 269 2.3E-22 T 22-04-2016 IPR002035 von Willebrand factor, type A HRM2_RS14575 f83f81ba3e19dbf4ed296f8d9b4db2d8 598 SUPERFAMILY SSF53300 85 272 5.79E-31 T 22-04-2016 IPR002035 von Willebrand factor, type A HRM2_RS14575 f83f81ba3e19dbf4ed296f8d9b4db2d8 598 Pfam PF07719 Tetratricopeptide repeat 423 456 2.3E-7 T 22-04-2016 IPR013105 Tetratricopeptide repeat 2 HRM2_RS14575 f83f81ba3e19dbf4ed296f8d9b4db2d8 598 SMART SM00327 88 281 1.0E-21 T 22-04-2016 IPR002035 von Willebrand factor, type A HRM2_RS14575 f83f81ba3e19dbf4ed296f8d9b4db2d8 598 Gene3D G3DSA:3.40.50.410 85 283 3.7E-22 T 22-04-2016 IPR002035 von Willebrand factor, type A HRM2_RS12620 9406a44530182c585202048dc42f98a8 366 PANTHER PTHR12526 84 366 1.2E-44 T 22-04-2016 HRM2_RS12620 9406a44530182c585202048dc42f98a8 366 PANTHER PTHR12526 8 58 1.2E-44 T 22-04-2016 HRM2_RS12620 9406a44530182c585202048dc42f98a8 366 Pfam PF00534 Glycosyl transferases group 1 192 305 1.3E-23 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 HRM2_RS12620 9406a44530182c585202048dc42f98a8 366 Gene3D G3DSA:3.40.50.2000 193 298 5.1E-17 T 22-04-2016 HRM2_RS12620 9406a44530182c585202048dc42f98a8 366 SUPERFAMILY SSF53756 2 365 1.36E-62 T 22-04-2016 HRM2_RS12620 9406a44530182c585202048dc42f98a8 366 Pfam PF13439 Glycosyltransferase Family 4 15 172 1.3E-16 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 SUPERFAMILY SSF55874 358 528 1.7E-47 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 Pfam PF00512 His Kinase A (phospho-acceptor) domain 304 369 1.4E-22 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 SMART SM00073 864 961 0.0087 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 416 530 2.0E-31 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 PANTHER PTHR24423 45 61 4.3E-165 T 22-04-2016 HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 PANTHER PTHR24423 283 546 4.3E-165 T 22-04-2016 HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 PANTHER PTHR24423 698 858 4.3E-165 T 22-04-2016 HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 SUPERFAMILY SSF158472 206 253 1.7E-5 T 22-04-2016 HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 PRINTS PR00344 Bacterial sensor protein C-terminal signature 457 471 3.0E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 PRINTS PR00344 Bacterial sensor protein C-terminal signature 516 529 3.0E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 PRINTS PR00344 Bacterial sensor protein C-terminal signature 492 510 3.0E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 PRINTS PR00344 Bacterial sensor protein C-terminal signature 475 485 3.0E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 SUPERFAMILY SSF52172 547 673 3.7E-27 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 SUPERFAMILY SSF52172 698 819 6.12E-36 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 Gene3D G3DSA:3.30.565.10 355 529 3.6E-47 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 SMART SM00387 416 532 1.5E-40 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 Gene3D G3DSA:3.40.50.2300 698 819 4.1E-42 T 22-04-2016 HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 SMART SM00388 304 369 1.4E-27 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 Pfam PF17152 Periplasmic sensor domain 47 166 2.0E-13 T 22-04-2016 IPR033417 Periplasmic sensor domain CHASE8 UniPathway: UPA00599 HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 PANTHER PTHR24423:SF382 45 61 4.3E-165 T 22-04-2016 HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 PANTHER PTHR24423:SF382 283 546 4.3E-165 T 22-04-2016 HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 PANTHER PTHR24423:SF382 698 858 4.3E-165 T 22-04-2016 HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 SUPERFAMILY SSF47226 848 955 4.06E-21 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 Gene3D G3DSA:1.10.287.130 297 354 6.5E-19 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 SUPERFAMILY SSF47384 287 370 1.2E-23 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 Pfam PF00072 Response regulator receiver domain 701 816 2.1E-24 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 Pfam PF00072 Response regulator receiver domain 553 669 6.0E-19 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 SMART SM00304 204 257 1.7E-7 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 Gene3D G3DSA:1.20.120.160 858 957 2.8E-22 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 Gene3D G3DSA:3.40.50.2300 548 678 5.8E-31 T 22-04-2016 HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 Pfam PF01627 Hpt domain 874 948 2.2E-11 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 Pfam PF00672 HAMP domain 186 253 1.2E-7 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 SMART SM00448 551 669 1.5E-25 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS21330 a42b562a82676eb0aee1b9a77d9b00ed 967 SMART SM00448 699 816 1.2E-35 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS06130 6d2a02ddc0478a4bee8b1654e4ad47ef 394 PANTHER PTHR21530:SF0 18 306 1.1E-87 T 22-04-2016 HRM2_RS06130 6d2a02ddc0478a4bee8b1654e4ad47ef 394 TIGRFAM TIGR00261 traB: TraB family protein 18 393 1.6E-108 T 22-04-2016 IPR005230 Pheromone shutdown, TraB, bacterial/archaeal HRM2_RS06130 6d2a02ddc0478a4bee8b1654e4ad47ef 394 Pfam PF01963 TraB family 15 233 1.5E-34 T 22-04-2016 IPR002816 Pheromone shutdown, TraB HRM2_RS06130 6d2a02ddc0478a4bee8b1654e4ad47ef 394 PANTHER PTHR21530 18 306 1.1E-87 T 22-04-2016 HRM2_RS06130 6d2a02ddc0478a4bee8b1654e4ad47ef 394 Gene3D G3DSA:3.90.190.20 164 242 2.1E-4 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HRM2_RS00270 34fea91147b2407782020a884c70a51c 306 PANTHER PTHR30508 49 305 6.8E-32 T 22-04-2016 HRM2_RS00270 34fea91147b2407782020a884c70a51c 306 Pfam PF01458 Uncharacterized protein family (UPF0051) 79 304 2.6E-45 T 22-04-2016 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 HRM2_RS00270 34fea91147b2407782020a884c70a51c 306 PANTHER PTHR30508:SF5 49 305 6.8E-32 T 22-04-2016 HRM2_RS00270 34fea91147b2407782020a884c70a51c 306 SUPERFAMILY SSF101960 38 305 4.97E-45 T 22-04-2016 HRM2_RS04565 45803cfd69906cbedf1f0121cafaeec3 587 Gene3D G3DSA:3.40.50.20 2 93 5.1E-36 T 22-04-2016 IPR016185 Pre-ATP-grasp domain HRM2_RS04565 45803cfd69906cbedf1f0121cafaeec3 587 SMART SM01209 101 293 7.5E-126 T 22-04-2016 HRM2_RS04565 45803cfd69906cbedf1f0121cafaeec3 587 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 429 582 31.166 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 HRM2_RS04565 45803cfd69906cbedf1f0121cafaeec3 587 Gene3D G3DSA:3.40.50.7700 425 585 3.8E-66 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 HRM2_RS04565 45803cfd69906cbedf1f0121cafaeec3 587 Gene3D G3DSA:3.30.1490.20 122 188 3.1E-26 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HRM2_RS04565 45803cfd69906cbedf1f0121cafaeec3 587 SMART SM01210 327 420 5.0E-51 T 22-04-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 HRM2_RS04565 45803cfd69906cbedf1f0121cafaeec3 587 SUPERFAMILY SSF52255 428 583 4.06E-58 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 HRM2_RS04565 45803cfd69906cbedf1f0121cafaeec3 587 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 420 6.1E-167 T 22-04-2016 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 HRM2_RS04565 45803cfd69906cbedf1f0121cafaeec3 587 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 420 41.408 T 22-04-2016 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 HRM2_RS04565 45803cfd69906cbedf1f0121cafaeec3 587 Gene3D G3DSA:3.90.600.10 328 420 6.1E-35 T 22-04-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 HRM2_RS04565 45803cfd69906cbedf1f0121cafaeec3 587 SUPERFAMILY SSF56059 102 317 2.65E-59 T 22-04-2016 HRM2_RS04565 45803cfd69906cbedf1f0121cafaeec3 587 SUPERFAMILY SSF52440 1 100 8.2E-35 T 22-04-2016 IPR016185 Pre-ATP-grasp domain HRM2_RS04565 45803cfd69906cbedf1f0121cafaeec3 587 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 5.0E-35 T 22-04-2016 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 HRM2_RS04565 45803cfd69906cbedf1f0121cafaeec3 587 Pfam PF00731 AIR carboxylase 428 575 5.9E-58 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 HRM2_RS04565 45803cfd69906cbedf1f0121cafaeec3 587 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 429 583 4.0E-58 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 HRM2_RS04565 45803cfd69906cbedf1f0121cafaeec3 587 PANTHER PTHR10520 1 423 3.6E-251 T 22-04-2016 HRM2_RS04565 45803cfd69906cbedf1f0121cafaeec3 587 SUPERFAMILY SSF51246 326 420 1.31E-31 T 22-04-2016 IPR011054 Rudiment single hybrid motif HRM2_RS04565 45803cfd69906cbedf1f0121cafaeec3 587 SMART SM01001 427 578 9.1E-87 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 HRM2_RS04565 45803cfd69906cbedf1f0121cafaeec3 587 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 329 417 1.3E-29 T 22-04-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 HRM2_RS04565 45803cfd69906cbedf1f0121cafaeec3 587 Gene3D G3DSA:3.30.470.20 189 324 2.2E-58 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS04565 45803cfd69906cbedf1f0121cafaeec3 587 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 293 4.4E-76 T 22-04-2016 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 HRM2_RS24405 8d0a9ac45cbedf6f2d04204dc0e3b142 161 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 75 153 2.2E-31 T 22-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 HRM2_RS24405 8d0a9ac45cbedf6f2d04204dc0e3b142 161 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 1 156 37.657 T 22-04-2016 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 HRM2_RS24405 8d0a9ac45cbedf6f2d04204dc0e3b142 161 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 74 153 2.4E-33 T 22-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 HRM2_RS24405 8d0a9ac45cbedf6f2d04204dc0e3b142 161 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 124 130 - T 22-04-2016 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 HRM2_RS24405 8d0a9ac45cbedf6f2d04204dc0e3b142 161 PANTHER PTHR10815 1 153 2.0E-50 T 22-04-2016 HRM2_RS24405 8d0a9ac45cbedf6f2d04204dc0e3b142 161 SUPERFAMILY SSF53155 1 79 7.85E-17 T 22-04-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 HRM2_RS24405 8d0a9ac45cbedf6f2d04204dc0e3b142 161 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 2 67 1.5E-5 T 22-04-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 HRM2_RS24405 8d0a9ac45cbedf6f2d04204dc0e3b142 161 PANTHER PTHR10815:SF5 1 153 2.0E-50 T 22-04-2016 HRM2_RS24405 8d0a9ac45cbedf6f2d04204dc0e3b142 161 SUPERFAMILY SSF46767 73 154 4.84E-30 T 22-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 HRM2_RS24405 8d0a9ac45cbedf6f2d04204dc0e3b142 161 Gene3D G3DSA:1.10.10.10 73 157 5.1E-33 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS21130 f455a03be5a3db1b5dba94c936ca6543 369 Gene3D G3DSA:3.40.640.10 23 248 9.8E-72 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS21130 f455a03be5a3db1b5dba94c936ca6543 369 SUPERFAMILY SSF53383 7 365 9.71E-105 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS21130 f455a03be5a3db1b5dba94c936ca6543 369 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 211 224 - T 22-04-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Reactome: REACT_13 HRM2_RS21130 f455a03be5a3db1b5dba94c936ca6543 369 Gene3D G3DSA:3.90.1150.10 249 367 7.6E-33 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS21130 f455a03be5a3db1b5dba94c936ca6543 369 PANTHER PTHR11751 4 366 5.9E-120 T 22-04-2016 HRM2_RS21130 f455a03be5a3db1b5dba94c936ca6543 369 Pfam PF00155 Aminotransferase class I and II 10 359 5.4E-61 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HRM2_RS21130 f455a03be5a3db1b5dba94c936ca6543 369 PANTHER PTHR11751:SF306 4 366 5.9E-120 T 22-04-2016 HRM2_RS08770 28eb2de61683bc7c4fce3939bcebd279 228 SUPERFAMILY SSF161098 16 226 2.35E-30 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS08770 28eb2de61683bc7c4fce3939bcebd279 228 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 44 223 4.2E-9 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS08770 28eb2de61683bc7c4fce3939bcebd279 228 PANTHER PTHR30183 1 228 6.7E-76 T 22-04-2016 HRM2_RS08770 28eb2de61683bc7c4fce3939bcebd279 228 Gene3D G3DSA:1.10.3720.10 19 227 7.1E-26 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS08770 28eb2de61683bc7c4fce3939bcebd279 228 PANTHER PTHR30183:SF4 1 228 6.7E-76 T 22-04-2016 HRM2_RS13965 954dad6469ca0ea019570ae2e58d2506 316 SUPERFAMILY SSF52151 5 182 2.88E-52 T 22-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 HRM2_RS13965 954dad6469ca0ea019570ae2e58d2506 316 SUPERFAMILY SSF52151 222 313 2.88E-52 T 22-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 HRM2_RS13965 954dad6469ca0ea019570ae2e58d2506 316 PANTHER PTHR14226:SF24 5 200 2.0E-73 T 22-04-2016 HRM2_RS13965 954dad6469ca0ea019570ae2e58d2506 316 PANTHER PTHR14226:SF24 231 315 2.0E-73 T 22-04-2016 HRM2_RS13965 954dad6469ca0ea019570ae2e58d2506 316 PANTHER PTHR14226 5 200 2.0E-73 T 22-04-2016 HRM2_RS13965 954dad6469ca0ea019570ae2e58d2506 316 PANTHER PTHR14226 231 315 2.0E-73 T 22-04-2016 HRM2_RS13965 954dad6469ca0ea019570ae2e58d2506 316 Gene3D G3DSA:3.40.1090.10 33 200 8.8E-14 T 22-04-2016 HRM2_RS13965 954dad6469ca0ea019570ae2e58d2506 316 Pfam PF01734 Patatin-like phospholipase 9 169 1.8E-18 T 22-04-2016 IPR002641 Patatin/Phospholipase A2-related GO:0006629 HRM2_RS08400 e0ca1e93561722c736000cc860a800e8 377 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 250 268 - T 22-04-2016 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 HRM2_RS08400 e0ca1e93561722c736000cc860a800e8 377 Gene3D G3DSA:3.30.70.20 221 254 2.5E-5 T 22-04-2016 HRM2_RS08400 e0ca1e93561722c736000cc860a800e8 377 PANTHER PTHR11615 243 377 2.2E-60 T 22-04-2016 HRM2_RS08400 e0ca1e93561722c736000cc860a800e8 377 PANTHER PTHR11615 6 54 2.2E-60 T 22-04-2016 HRM2_RS08400 e0ca1e93561722c736000cc860a800e8 377 PANTHER PTHR11615:SF112 243 377 2.2E-60 T 22-04-2016 HRM2_RS08400 e0ca1e93561722c736000cc860a800e8 377 PANTHER PTHR11615:SF112 6 54 2.2E-60 T 22-04-2016 HRM2_RS08400 e0ca1e93561722c736000cc860a800e8 377 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 216 227 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS08400 e0ca1e93561722c736000cc860a800e8 377 Pfam PF12838 4Fe-4S dicluster domain 172 230 1.6E-9 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS08400 e0ca1e93561722c736000cc860a800e8 377 SUPERFAMILY SSF54292 7 105 1.22E-24 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 HRM2_RS08400 e0ca1e93561722c736000cc860a800e8 377 Gene3D G3DSA:3.40.50.740 302 374 2.7E-26 T 22-04-2016 HRM2_RS08400 e0ca1e93561722c736000cc860a800e8 377 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 7 78 6.6E-16 T 22-04-2016 HRM2_RS08400 e0ca1e93561722c736000cc860a800e8 377 Gene3D G3DSA:3.10.20.30 9 58 3.6E-9 T 22-04-2016 IPR012675 Beta-grasp domain HRM2_RS08400 e0ca1e93561722c736000cc860a800e8 377 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 246 297 3.4E-15 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS08400 e0ca1e93561722c736000cc860a800e8 377 Pfam PF00384 Molybdopterin oxidoreductase 302 377 8.6E-14 T 22-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 HRM2_RS08400 e0ca1e93561722c736000cc860a800e8 377 SMART SM00926 245 299 6.5E-16 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS08400 e0ca1e93561722c736000cc860a800e8 377 Gene3D G3DSA:3.30.70.20 155 220 7.1E-16 T 22-04-2016 HRM2_RS08400 e0ca1e93561722c736000cc860a800e8 377 SUPERFAMILY SSF54862 78 233 8.37E-34 T 22-04-2016 HRM2_RS08400 e0ca1e93561722c736000cc860a800e8 377 SUPERFAMILY SSF53706 214 376 8.64E-53 T 22-04-2016 HRM2_RS08400 e0ca1e93561722c736000cc860a800e8 377 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 34 51 - T 22-04-2016 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 HRM2_RS08400 e0ca1e93561722c736000cc860a800e8 377 Gene3D G3DSA:2.20.25.90 255 300 8.8E-21 T 22-04-2016 HRM2_RS07145 56101ef022c8e8572045ab32b258cf0d 608 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 548 559 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS07145 56101ef022c8e8572045ab32b258cf0d 608 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 515 526 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS07145 56101ef022c8e8572045ab32b258cf0d 608 Gene3D G3DSA:3.50.50.60 155 290 5.5E-32 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS07145 56101ef022c8e8572045ab32b258cf0d 608 Gene3D G3DSA:3.50.50.60 438 484 5.5E-32 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS07145 56101ef022c8e8572045ab32b258cf0d 608 PANTHER PTHR10742 102 194 4.9E-13 T 22-04-2016 HRM2_RS07145 56101ef022c8e8572045ab32b258cf0d 608 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 154 278 8.2E-12 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS07145 56101ef022c8e8572045ab32b258cf0d 608 Gene3D G3DSA:3.30.70.20 522 573 1.2E-14 T 22-04-2016 HRM2_RS07145 56101ef022c8e8572045ab32b258cf0d 608 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 154 176 1.9E-9 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HRM2_RS07145 56101ef022c8e8572045ab32b258cf0d 608 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 255 263 1.9E-9 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HRM2_RS07145 56101ef022c8e8572045ab32b258cf0d 608 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 468 487 1.9E-9 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HRM2_RS07145 56101ef022c8e8572045ab32b258cf0d 608 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 442 464 7.9E-7 T 22-04-2016 HRM2_RS07145 56101ef022c8e8572045ab32b258cf0d 608 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 272 7.9E-7 T 22-04-2016 HRM2_RS07145 56101ef022c8e8572045ab32b258cf0d 608 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 174 7.9E-7 T 22-04-2016 HRM2_RS07145 56101ef022c8e8572045ab32b258cf0d 608 SUPERFAMILY SSF51905 136 483 8.42E-28 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS07145 56101ef022c8e8572045ab32b258cf0d 608 SUPERFAMILY SSF54862 503 566 5.02E-20 T 22-04-2016 HRM2_RS07145 56101ef022c8e8572045ab32b258cf0d 608 Pfam PF13187 4Fe-4S dicluster domain 514 562 3.0E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS07145 56101ef022c8e8572045ab32b258cf0d 608 PANTHER PTHR10742:SF263 102 194 4.9E-13 T 22-04-2016 HRM2_RS07145 56101ef022c8e8572045ab32b258cf0d 608 Gene3D G3DSA:3.30.70.20 305 332 2.1E-4 T 22-04-2016 HRM2_RS07145 56101ef022c8e8572045ab32b258cf0d 608 Gene3D G3DSA:3.30.70.20 502 521 2.1E-4 T 22-04-2016 HRM2_RS07070 f6b70633991235022c2e30a150343df3 222 SUPERFAMILY SSF52242 96 221 2.75E-30 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS07070 f6b70633991235022c2e30a150343df3 222 Pfam PF02310 B12 binding domain 104 199 3.8E-21 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS07070 f6b70633991235022c2e30a150343df3 222 Gene3D G3DSA:3.40.50.280 95 221 3.9E-32 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS22155 6171c18607e81adb0273263206c3455b 500 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 388 408 1.2E-30 T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 HRM2_RS22155 6171c18607e81adb0273263206c3455b 500 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 85 111 1.2E-30 T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 HRM2_RS22155 6171c18607e81adb0273263206c3455b 500 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 428 448 1.2E-30 T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 HRM2_RS22155 6171c18607e81adb0273263206c3455b 500 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 311 330 1.2E-30 T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 HRM2_RS22155 6171c18607e81adb0273263206c3455b 500 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 1.2E-30 T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 HRM2_RS22155 6171c18607e81adb0273263206c3455b 500 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 1.2E-30 T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 HRM2_RS22155 6171c18607e81adb0273263206c3455b 500 SUPERFAMILY SSF161070 4 477 3.53E-151 T 22-04-2016 HRM2_RS22155 6171c18607e81adb0273263206c3455b 500 Pfam PF00209 Sodium:neurotransmitter symporter family 4 118 6.0E-38 T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 HRM2_RS22155 6171c18607e81adb0273263206c3455b 500 Pfam PF00209 Sodium:neurotransmitter symporter family 125 476 1.1E-80 T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 HRM2_RS22155 6171c18607e81adb0273263206c3455b 500 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 28 42 - T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 HRM2_RS22155 6171c18607e81adb0273263206c3455b 500 PANTHER PTHR11616 1 488 4.7E-179 T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 HRM2_RS22155 6171c18607e81adb0273263206c3455b 500 PANTHER PTHR11616:SF169 1 488 4.7E-179 T 22-04-2016 HRM2_RS14175 aa152828d2a6b49c80c5ccee4c72c409 188 SUPERFAMILY SSF54626 30 168 1.44E-9 T 22-04-2016 IPR016087 Chalcone isomerase GO:0016872 HRM2_RS14175 aa152828d2a6b49c80c5ccee4c72c409 188 Pfam PF16036 Chalcone isomerase-like 21 187 8.9E-45 T 22-04-2016 IPR016087 Chalcone isomerase GO:0016872 HRM2_RS05435 f98aaea6cd7e2d8debeb6fd5697e0894 231 Pfam PF04350 Pilus assembly protein, PilO 77 217 8.6E-45 T 22-04-2016 IPR007445 Pilus assembly protein, PilO HRM2_RS05435 f98aaea6cd7e2d8debeb6fd5697e0894 231 PANTHER PTHR39555:SF1 27 230 1.3E-45 T 22-04-2016 HRM2_RS05435 f98aaea6cd7e2d8debeb6fd5697e0894 231 Gene3D G3DSA:3.30.70.60 121 227 9.0E-37 T 22-04-2016 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 HRM2_RS05435 f98aaea6cd7e2d8debeb6fd5697e0894 231 PANTHER PTHR39555 27 230 1.3E-45 T 22-04-2016 HRM2_RS25385 64086890d78dfd04623f4859d745ada6 667 SMART SM00091 155 222 6.2E-7 T 22-04-2016 IPR000014 PAS domain HRM2_RS25385 64086890d78dfd04623f4859d745ada6 667 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 152 276 3.6E-15 T 22-04-2016 IPR000014 PAS domain HRM2_RS25385 64086890d78dfd04623f4859d745ada6 667 SUPERFAMILY SSF52172 542 662 3.7E-28 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS25385 64086890d78dfd04623f4859d745ada6 667 SUPERFAMILY SSF47384 285 356 1.18E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25385 64086890d78dfd04623f4859d745ada6 667 PRINTS PR00344 Bacterial sensor protein C-terminal signature 507 520 7.9E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25385 64086890d78dfd04623f4859d745ada6 667 PRINTS PR00344 Bacterial sensor protein C-terminal signature 452 466 7.9E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25385 64086890d78dfd04623f4859d745ada6 667 PRINTS PR00344 Bacterial sensor protein C-terminal signature 483 501 7.9E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25385 64086890d78dfd04623f4859d745ada6 667 PRINTS PR00344 Bacterial sensor protein C-terminal signature 470 480 7.9E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25385 64086890d78dfd04623f4859d745ada6 667 SMART SM00388 292 358 7.4E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25385 64086890d78dfd04623f4859d745ada6 667 Gene3D G3DSA:3.30.565.10 344 523 8.4E-37 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25385 64086890d78dfd04623f4859d745ada6 667 Gene3D G3DSA:3.30.450.20 148 268 3.9E-14 T 22-04-2016 HRM2_RS25385 64086890d78dfd04623f4859d745ada6 667 Gene3D G3DSA:3.40.50.2300 543 664 3.6E-28 T 22-04-2016 HRM2_RS25385 64086890d78dfd04623f4859d745ada6 667 Gene3D G3DSA:3.40.50.2300 6 147 3.8E-37 T 22-04-2016 HRM2_RS25385 64086890d78dfd04623f4859d745ada6 667 SMART SM00387 399 523 3.0E-30 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25385 64086890d78dfd04623f4859d745ada6 667 Pfam PF00512 His Kinase A (phospho-acceptor) domain 294 356 4.7E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25385 64086890d78dfd04623f4859d745ada6 667 Gene3D G3DSA:1.10.287.130 287 343 2.3E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25385 64086890d78dfd04623f4859d745ada6 667 PANTHER PTHR24423 153 661 8.4E-120 T 22-04-2016 HRM2_RS25385 64086890d78dfd04623f4859d745ada6 667 SMART SM00448 7 119 2.5E-33 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS25385 64086890d78dfd04623f4859d745ada6 667 SMART SM00448 544 657 4.0E-21 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS25385 64086890d78dfd04623f4859d745ada6 667 PANTHER PTHR24423:SF544 153 661 8.4E-120 T 22-04-2016 HRM2_RS25385 64086890d78dfd04623f4859d745ada6 667 SUPERFAMILY SSF55785 147 268 4.89E-13 T 22-04-2016 IPR000014 PAS domain HRM2_RS25385 64086890d78dfd04623f4859d745ada6 667 Pfam PF00072 Response regulator receiver domain 9 113 2.1E-27 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS25385 64086890d78dfd04623f4859d745ada6 667 Pfam PF00072 Response regulator receiver domain 546 657 2.1E-18 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS25385 64086890d78dfd04623f4859d745ada6 667 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 401 520 2.7E-19 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25385 64086890d78dfd04623f4859d745ada6 667 SUPERFAMILY SSF52172 6 156 6.26E-39 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS25385 64086890d78dfd04623f4859d745ada6 667 SUPERFAMILY SSF55874 347 521 2.62E-37 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS21165 40bd6c8b5d7832ec900b236ac31a998a 444 PANTHER PTHR35894 2 260 3.1E-43 T 22-04-2016 HRM2_RS21165 40bd6c8b5d7832ec900b236ac31a998a 444 Pfam PF13401 AAA domain 41 166 7.7E-16 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS21165 40bd6c8b5d7832ec900b236ac31a998a 444 Gene3D G3DSA:3.40.50.300 51 174 3.8E-11 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21165 40bd6c8b5d7832ec900b236ac31a998a 444 SMART SM00382 41 184 1.9E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS21165 40bd6c8b5d7832ec900b236ac31a998a 444 PANTHER PTHR35894:SF1 2 260 3.1E-43 T 22-04-2016 HRM2_RS21165 40bd6c8b5d7832ec900b236ac31a998a 444 SUPERFAMILY SSF52540 28 260 1.01E-27 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21165 40bd6c8b5d7832ec900b236ac31a998a 444 Gene3D G3DSA:3.40.50.300 30 50 2.0E-5 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21165 40bd6c8b5d7832ec900b236ac31a998a 444 Gene3D G3DSA:3.40.50.300 333 402 2.0E-5 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02355 19e307de0247e4fea1dbf30e69017f35 283 PANTHER PTHR21299:SF1 1 280 3.2E-125 T 22-04-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 HRM2_RS02355 19e307de0247e4fea1dbf30e69017f35 283 Hamap MF_00158 Pantothenate synthetase [panC]. 2 279 36.835 T 22-04-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 HRM2_RS02355 19e307de0247e4fea1dbf30e69017f35 283 Pfam PF02569 Pantoate-beta-alanine ligase 3 277 6.8E-96 T 22-04-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 HRM2_RS02355 19e307de0247e4fea1dbf30e69017f35 283 Gene3D G3DSA:3.40.50.620 1 174 1.8E-71 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS02355 19e307de0247e4fea1dbf30e69017f35 283 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 280 7.8E-97 T 22-04-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 HRM2_RS02355 19e307de0247e4fea1dbf30e69017f35 283 SUPERFAMILY SSF52374 1 280 6.22E-102 T 22-04-2016 HRM2_RS02355 19e307de0247e4fea1dbf30e69017f35 283 Gene3D G3DSA:3.30.1300.10 175 282 3.4E-31 T 22-04-2016 HRM2_RS02355 19e307de0247e4fea1dbf30e69017f35 283 PANTHER PTHR21299 1 280 3.2E-125 T 22-04-2016 HRM2_RS12870 e0ceefab8e0ea2553465c52349093f2d 779 PANTHER PTHR12815:SF11 82 779 3.3E-76 T 22-04-2016 HRM2_RS12870 e0ceefab8e0ea2553465c52349093f2d 779 Gene3D G3DSA:2.40.160.50 579 779 3.8E-18 T 22-04-2016 HRM2_RS12870 e0ceefab8e0ea2553465c52349093f2d 779 Pfam PF07244 Surface antigen variable number repeat 375 449 9.2E-8 T 22-04-2016 IPR010827 Surface antigen variable number GO:0019867 HRM2_RS12870 e0ceefab8e0ea2553465c52349093f2d 779 Pfam PF07244 Surface antigen variable number repeat 296 372 4.0E-5 T 22-04-2016 IPR010827 Surface antigen variable number GO:0019867 HRM2_RS12870 e0ceefab8e0ea2553465c52349093f2d 779 Pfam PF07244 Surface antigen variable number repeat 202 290 2.1E-9 T 22-04-2016 IPR010827 Surface antigen variable number GO:0019867 HRM2_RS12870 e0ceefab8e0ea2553465c52349093f2d 779 Pfam PF07244 Surface antigen variable number repeat 36 118 1.8E-4 T 22-04-2016 IPR010827 Surface antigen variable number GO:0019867 HRM2_RS12870 e0ceefab8e0ea2553465c52349093f2d 779 PANTHER PTHR12815 82 779 3.3E-76 T 22-04-2016 HRM2_RS12870 e0ceefab8e0ea2553465c52349093f2d 779 Pfam PF01103 Surface antigen 478 779 2.0E-40 T 22-04-2016 IPR000184 Bacterial surface antigen (D15) GO:0019867 HRM2_RS24360 41c7e1d6ad91474cd773279bbce141f6 251 Pfam PF00005 ABC transporter 25 173 1.5E-30 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS24360 41c7e1d6ad91474cd773279bbce141f6 251 SMART SM00382 33 222 7.2E-16 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS24360 41c7e1d6ad91474cd773279bbce141f6 251 PANTHER PTHR24220:SF483 10 248 8.2E-89 T 22-04-2016 HRM2_RS24360 41c7e1d6ad91474cd773279bbce141f6 251 PANTHER PTHR24220 10 248 8.2E-89 T 22-04-2016 HRM2_RS24360 41c7e1d6ad91474cd773279bbce141f6 251 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS24360 41c7e1d6ad91474cd773279bbce141f6 251 Gene3D G3DSA:3.40.50.300 5 249 6.3E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24360 41c7e1d6ad91474cd773279bbce141f6 251 SUPERFAMILY SSF52540 7 246 6.41E-63 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03450 0e9fcccdda72a59ed479e69650aa449b 147 Gene3D G3DSA:3.40.50.620 1 141 2.2E-11 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS03450 0e9fcccdda72a59ed479e69650aa449b 147 SUPERFAMILY SSF52402 1 141 9.21E-9 T 22-04-2016 HRM2_RS20415 a072c7185b383f1bbf69b47768b6f54e 441 SMART SM00670 3 133 0.001 T 22-04-2016 IPR002716 PIN domain HRM2_RS20415 a072c7185b383f1bbf69b47768b6f54e 441 Gene3D G3DSA:3.40.50.1010 96 147 2.2E-16 T 22-04-2016 IPR029060 PIN domain-like HRM2_RS20415 a072c7185b383f1bbf69b47768b6f54e 441 Gene3D G3DSA:3.40.50.1010 3 63 2.2E-16 T 22-04-2016 IPR029060 PIN domain-like HRM2_RS20415 a072c7185b383f1bbf69b47768b6f54e 441 SUPERFAMILY SSF52540 228 416 1.74E-27 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20415 a072c7185b383f1bbf69b47768b6f54e 441 SUPERFAMILY SSF52540 160 179 1.74E-27 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20415 a072c7185b383f1bbf69b47768b6f54e 441 Pfam PF02562 PhoH-like protein 229 437 3.9E-52 T 22-04-2016 IPR003714 PhoH-like protein GO:0005524 HRM2_RS20415 a072c7185b383f1bbf69b47768b6f54e 441 Gene3D G3DSA:3.40.50.300 228 440 3.1E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20415 a072c7185b383f1bbf69b47768b6f54e 441 PANTHER PTHR30473:SF2 2 441 4.2E-151 T 22-04-2016 HRM2_RS20415 a072c7185b383f1bbf69b47768b6f54e 441 Pfam PF13638 PIN domain 5 146 4.2E-30 T 22-04-2016 IPR002716 PIN domain HRM2_RS20415 a072c7185b383f1bbf69b47768b6f54e 441 PANTHER PTHR30473 2 441 4.2E-151 T 22-04-2016 HRM2_RS20415 a072c7185b383f1bbf69b47768b6f54e 441 SUPERFAMILY SSF88723 2 64 1.37E-14 T 22-04-2016 IPR029060 PIN domain-like HRM2_RS20415 a072c7185b383f1bbf69b47768b6f54e 441 SUPERFAMILY SSF88723 96 145 1.37E-14 T 22-04-2016 IPR029060 PIN domain-like HRM2_RS20610 6138b6033716cc0b734b50aac2c3279f 189 Gene3D G3DSA:2.60.120.10 59 186 2.1E-25 T 22-04-2016 IPR014710 RmlC-like jelly roll fold HRM2_RS20610 6138b6033716cc0b734b50aac2c3279f 189 SMART SM00530 9 64 0.0019 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS20610 6138b6033716cc0b734b50aac2c3279f 189 PANTHER PTHR10245:SF22 6 188 8.2E-28 T 22-04-2016 HRM2_RS20610 6138b6033716cc0b734b50aac2c3279f 189 PANTHER PTHR10245 6 188 8.2E-28 T 22-04-2016 HRM2_RS20610 6138b6033716cc0b734b50aac2c3279f 189 SUPERFAMILY SSF47413 6 73 3.1E-9 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS20610 6138b6033716cc0b734b50aac2c3279f 189 Gene3D G3DSA:1.10.260.40 5 58 2.2E-11 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS20610 6138b6033716cc0b734b50aac2c3279f 189 SUPERFAMILY SSF51182 57 185 9.57E-25 T 22-04-2016 IPR011051 RmlC-like cupin domain HRM2_RS20610 6138b6033716cc0b734b50aac2c3279f 189 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 9 66 4.0E-8 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS20610 6138b6033716cc0b734b50aac2c3279f 189 Pfam PF07883 Cupin domain 116 184 3.1E-12 T 22-04-2016 IPR013096 Cupin 2, conserved barrel HRM2_RS18965 35830ea666c974198ac3a27ebb961a7f 257 Gene3D G3DSA:3.40.50.620 1 256 1.0E-85 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS18965 35830ea666c974198ac3a27ebb961a7f 257 SMART SM00893 23 212 3.5E-53 T 22-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 HRM2_RS18965 35830ea666c974198ac3a27ebb961a7f 257 SUPERFAMILY SSF52402 1 252 3.63E-73 T 22-04-2016 HRM2_RS18965 35830ea666c974198ac3a27ebb961a7f 257 PANTHER PTHR21294 1 257 7.8E-93 T 22-04-2016 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 HRM2_RS18965 35830ea666c974198ac3a27ebb961a7f 257 PIRSF PIRSF000090 1 257 2.1E-79 T 22-04-2016 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 HRM2_RS18965 35830ea666c974198ac3a27ebb961a7f 257 PANTHER PTHR21294:SF0 1 257 7.8E-93 T 22-04-2016 HRM2_RS18965 35830ea666c974198ac3a27ebb961a7f 257 Pfam PF01012 Electron transfer flavoprotein domain 27 207 7.4E-49 T 22-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 HRM2_RS24230 0a9ab00517962a632843979f0dcc3cd1 555 SUPERFAMILY SSF46785 499 547 1.08E-5 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS24230 0a9ab00517962a632843979f0dcc3cd1 555 PANTHER PTHR30595 1 416 2.4E-24 T 22-04-2016 HRM2_RS24230 0a9ab00517962a632843979f0dcc3cd1 555 Pfam PF04326 Putative DNA-binding domain 16 110 5.5E-15 T 22-04-2016 IPR007421 Schlafen, AAA domain GO:0005524 HRM2_RS24230 0a9ab00517962a632843979f0dcc3cd1 555 PANTHER PTHR30595:SF6 1 416 2.4E-24 T 22-04-2016 HRM2_RS24230 0a9ab00517962a632843979f0dcc3cd1 555 SUPERFAMILY SSF46785 421 497 4.77E-7 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS24230 0a9ab00517962a632843979f0dcc3cd1 555 Gene3D G3DSA:1.10.10.10 420 477 7.9E-5 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS24230 0a9ab00517962a632843979f0dcc3cd1 555 Gene3D G3DSA:1.10.10.10 500 549 2.3E-5 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS24230 0a9ab00517962a632843979f0dcc3cd1 555 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 307 388 3.3E-17 T 22-04-2016 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain HRM2_RS18465 56e2196662e2241f65c5c11da7453a73 544 Gene3D G3DSA:3.40.50.620 265 526 1.2E-70 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS18465 56e2196662e2241f65c5c11da7453a73 544 PIRSF PIRSF006630 1 544 3.1E-174 T 22-04-2016 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|UniPathway: UPA00253 HRM2_RS18465 56e2196662e2241f65c5c11da7453a73 544 PANTHER PTHR23090 1 531 3.4E-134 T 22-04-2016 HRM2_RS18465 56e2196662e2241f65c5c11da7453a73 544 SUPERFAMILY SSF56317 1 252 2.62E-53 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 HRM2_RS18465 56e2196662e2241f65c5c11da7453a73 544 SUPERFAMILY SSF52402 264 526 7.64E-71 T 22-04-2016 HRM2_RS18465 56e2196662e2241f65c5c11da7453a73 544 TIGRFAM TIGR00552 nadE: NAD+ synthetase 279 520 2.4E-62 T 22-04-2016 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|UniPathway: UPA00253 HRM2_RS18465 56e2196662e2241f65c5c11da7453a73 544 Pfam PF00795 Carbon-nitrogen hydrolase 2 251 6.5E-18 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 HRM2_RS18465 56e2196662e2241f65c5c11da7453a73 544 Gene3D G3DSA:3.60.110.10 1 254 7.5E-54 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 HRM2_RS18465 56e2196662e2241f65c5c11da7453a73 544 Pfam PF02540 NAD synthase 272 518 9.9E-73 T 22-04-2016 IPR022310 NAD/GMP synthase HRM2_RS18465 56e2196662e2241f65c5c11da7453a73 544 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 33 48 - T 22-04-2016 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 HRM2_RS14240 67c8053cbacf679457bf106d86b80dea 527 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 15 511 2.5E-84 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ HRM2_RS14240 67c8053cbacf679457bf106d86b80dea 527 Pfam PF03023 MviN-like protein 41 470 3.6E-69 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ HRM2_RS14240 67c8053cbacf679457bf106d86b80dea 527 PANTHER PTHR11206 221 444 4.6E-25 T 22-04-2016 HRM2_RS14240 67c8053cbacf679457bf106d86b80dea 527 PANTHER PTHR11206 505 510 4.6E-25 T 22-04-2016 HRM2_RS14240 67c8053cbacf679457bf106d86b80dea 527 PANTHER PTHR11206 81 86 4.6E-25 T 22-04-2016 HRM2_RS14240 67c8053cbacf679457bf106d86b80dea 527 PANTHER PTHR11206 1 10 4.6E-25 T 22-04-2016 HRM2_RS14240 67c8053cbacf679457bf106d86b80dea 527 PRINTS PR01806 Virulence factor MviN signature 362 381 3.3E-28 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ HRM2_RS14240 67c8053cbacf679457bf106d86b80dea 527 PRINTS PR01806 Virulence factor MviN signature 164 185 3.3E-28 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ HRM2_RS14240 67c8053cbacf679457bf106d86b80dea 527 PRINTS PR01806 Virulence factor MviN signature 265 291 3.3E-28 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ HRM2_RS14240 67c8053cbacf679457bf106d86b80dea 527 PRINTS PR01806 Virulence factor MviN signature 414 431 3.3E-28 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ HRM2_RS14240 67c8053cbacf679457bf106d86b80dea 527 PRINTS PR01806 Virulence factor MviN signature 41 60 3.3E-28 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ HRM2_RS14240 67c8053cbacf679457bf106d86b80dea 527 PRINTS PR01806 Virulence factor MviN signature 60 76 3.3E-28 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ HRM2_RS14240 67c8053cbacf679457bf106d86b80dea 527 PANTHER PTHR11206:SF90 221 444 4.6E-25 T 22-04-2016 HRM2_RS14240 67c8053cbacf679457bf106d86b80dea 527 PANTHER PTHR11206:SF90 505 510 4.6E-25 T 22-04-2016 HRM2_RS14240 67c8053cbacf679457bf106d86b80dea 527 PANTHER PTHR11206:SF90 81 86 4.6E-25 T 22-04-2016 HRM2_RS14240 67c8053cbacf679457bf106d86b80dea 527 PANTHER PTHR11206:SF90 1 10 4.6E-25 T 22-04-2016 HRM2_RS14240 67c8053cbacf679457bf106d86b80dea 527 PIRSF PIRSF002869 6 519 2.1E-99 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ HRM2_RS00625 50d68ea130c16730eb557fc9511b639d 124 PANTHER PTHR35810 8 124 2.8E-43 T 22-04-2016 HRM2_RS00625 50d68ea130c16730eb557fc9511b639d 124 PANTHER PTHR35810:SF1 8 124 2.8E-43 T 22-04-2016 HRM2_RS00625 50d68ea130c16730eb557fc9511b639d 124 Pfam PF13310 Virulence protein RhuM family 70 115 5.0E-14 T 22-04-2016 IPR011204 Virulence protein RhuM-like HRM2_RS16275 a0b3b6f7297c0931d4af0febaa41d51d 639 Gene3D G3DSA:1.10.10.10 517 576 9.9E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS16275 a0b3b6f7297c0931d4af0febaa41d51d 639 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 29 44 - T 22-04-2016 IPR031157 Tr-type G domain, conserved site HRM2_RS16275 a0b3b6f7297c0931d4af0febaa41d51d 639 SUPERFAMILY SSF46785 517 576 7.26E-11 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS16275 a0b3b6f7297c0931d4af0febaa41d51d 639 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 159 2.1E-13 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HRM2_RS16275 a0b3b6f7297c0931d4af0febaa41d51d 639 Gene3D G3DSA:2.40.30.10 270 354 1.8E-8 T 22-04-2016 HRM2_RS16275 a0b3b6f7297c0931d4af0febaa41d51d 639 SUPERFAMILY SSF46785 586 637 1.61E-14 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS16275 a0b3b6f7297c0931d4af0febaa41d51d 639 SUPERFAMILY SSF52540 3 195 4.67E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16275 a0b3b6f7297c0931d4af0febaa41d51d 639 PANTHER PTHR23115:SF129 595 619 3.6E-143 T 22-04-2016 HRM2_RS16275 a0b3b6f7297c0931d4af0febaa41d51d 639 TIGRFAM TIGR00475 selB: selenocysteine-specific translation elongation factor 4 636 9.6E-110 T 22-04-2016 IPR004535 Translation elongation factor, selenocysteine-specific GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 HRM2_RS16275 a0b3b6f7297c0931d4af0febaa41d51d 639 SUPERFAMILY SSF46785 441 512 1.25E-11 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS16275 a0b3b6f7297c0931d4af0febaa41d51d 639 Gene3D G3DSA:3.40.50.300 5 172 1.3E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16275 a0b3b6f7297c0931d4af0febaa41d51d 639 PANTHER PTHR23115 595 619 3.6E-143 T 22-04-2016 HRM2_RS16275 a0b3b6f7297c0931d4af0febaa41d51d 639 SUPERFAMILY SSF50465 266 363 2.88E-24 T 22-04-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal HRM2_RS16275 a0b3b6f7297c0931d4af0febaa41d51d 639 Gene3D G3DSA:2.40.30.10 180 262 1.1E-27 T 22-04-2016 HRM2_RS16275 a0b3b6f7297c0931d4af0febaa41d51d 639 Pfam PF00009 Elongation factor Tu GTP binding domain 4 165 5.2E-30 T 22-04-2016 HRM2_RS16275 a0b3b6f7297c0931d4af0febaa41d51d 639 Gene3D G3DSA:1.10.10.10 440 508 1.4E-18 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS16275 a0b3b6f7297c0931d4af0febaa41d51d 639 Gene3D G3DSA:1.10.10.10 580 637 6.3E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS16275 a0b3b6f7297c0931d4af0febaa41d51d 639 Pfam PF09106 Elongation factor SelB, winged helix 451 507 3.8E-15 T 22-04-2016 IPR015190 Translation elongation factor SelB, winged helix, type 2 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 HRM2_RS16275 a0b3b6f7297c0931d4af0febaa41d51d 639 Pfam PF09107 Elongation factor SelB, winged helix 591 635 6.1E-19 T 22-04-2016 IPR015191 Translation elongation factor SelB, winged helix, type 3 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 HRM2_RS16275 a0b3b6f7297c0931d4af0febaa41d51d 639 SUPERFAMILY SSF50447 174 268 1.61E-24 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain HRM2_RS16275 a0b3b6f7297c0931d4af0febaa41d51d 639 PANTHER PTHR23115 2 367 3.6E-143 T 22-04-2016 HRM2_RS16275 a0b3b6f7297c0931d4af0febaa41d51d 639 PANTHER PTHR23115:SF129 2 367 3.6E-143 T 22-04-2016 HRM2_RS06045 bf1b05eaaaba493d069a9a3f040375ec 488 Pfam PF00990 Diguanylate cyclase, GGDEF domain 319 475 5.6E-44 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS06045 bf1b05eaaaba493d069a9a3f040375ec 488 Gene3D G3DSA:3.30.450.20 160 282 4.1E-10 T 22-04-2016 HRM2_RS06045 bf1b05eaaaba493d069a9a3f040375ec 488 PANTHER PTHR10799 1 98 1.1E-24 T 22-04-2016 HRM2_RS06045 bf1b05eaaaba493d069a9a3f040375ec 488 PANTHER PTHR10799 352 475 1.1E-24 T 22-04-2016 HRM2_RS06045 bf1b05eaaaba493d069a9a3f040375ec 488 SUPERFAMILY SSF55073 324 477 5.26E-48 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS06045 bf1b05eaaaba493d069a9a3f040375ec 488 SMART SM00267 308 479 1.9E-60 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS06045 bf1b05eaaaba493d069a9a3f040375ec 488 Gene3D G3DSA:3.30.70.270 321 477 1.2E-51 T 22-04-2016 HRM2_RS06045 bf1b05eaaaba493d069a9a3f040375ec 488 PANTHER PTHR10799:SF750 1 98 1.1E-24 T 22-04-2016 HRM2_RS06045 bf1b05eaaaba493d069a9a3f040375ec 488 PANTHER PTHR10799:SF750 352 475 1.1E-24 T 22-04-2016 HRM2_RS06045 bf1b05eaaaba493d069a9a3f040375ec 488 Pfam PF02743 Cache domain 58 271 1.0E-17 T 22-04-2016 IPR033479 Double Cache domain 1 HRM2_RS06045 bf1b05eaaaba493d069a9a3f040375ec 488 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 315 478 1.9E-50 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS23610 c22d97e6ca88d89b6246102237aff31d 332 PANTHER PTHR11228 14 261 9.6E-37 T 22-04-2016 HRM2_RS23610 c22d97e6ca88d89b6246102237aff31d 332 Pfam PF13353 4Fe-4S single cluster domain 17 122 2.6E-8 T 22-04-2016 HRM2_RS23610 c22d97e6ca88d89b6246102237aff31d 332 Gene3D G3DSA:3.20.20.70 13 270 6.8E-45 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS23610 c22d97e6ca88d89b6246102237aff31d 332 SMART SM00729 13 216 0.0036 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS23610 c22d97e6ca88d89b6246102237aff31d 332 Pfam PF04055 Radical SAM superfamily 20 166 3.9E-19 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS23610 c22d97e6ca88d89b6246102237aff31d 332 SUPERFAMILY SSF102114 14 267 3.79E-48 T 22-04-2016 HRM2_RS16635 2bb8eb9e905cf0214821b4883ad2477e 574 PANTHER PTHR33490 346 550 7.1E-12 T 22-04-2016 HRM2_RS16635 2bb8eb9e905cf0214821b4883ad2477e 574 Gene3D G3DSA:3.90.260.10 427 504 7.9E-5 T 22-04-2016 IPR002931 Transglutaminase-like HRM2_RS16635 2bb8eb9e905cf0214821b4883ad2477e 574 SUPERFAMILY SSF54001 428 551 6.87E-23 T 22-04-2016 HRM2_RS16635 2bb8eb9e905cf0214821b4883ad2477e 574 SMART SM00460 476 535 2.7E-11 T 22-04-2016 IPR002931 Transglutaminase-like HRM2_RS16635 2bb8eb9e905cf0214821b4883ad2477e 574 Pfam PF01841 Transglutaminase-like superfamily 435 533 1.8E-17 T 22-04-2016 IPR002931 Transglutaminase-like HRM2_RS04020 bcdecb1335968fae344f62d250c57a43 239 Pfam PF07729 FCD domain 100 221 2.3E-24 T 22-04-2016 IPR011711 GntR, C-terminal HRM2_RS04020 bcdecb1335968fae344f62d250c57a43 239 Gene3D G3DSA:1.10.10.10 9 75 7.0E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS04020 bcdecb1335968fae344f62d250c57a43 239 SUPERFAMILY SSF46785 3 75 1.25E-16 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS04020 bcdecb1335968fae344f62d250c57a43 239 SUPERFAMILY SSF48008 99 226 7.32E-24 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS04020 bcdecb1335968fae344f62d250c57a43 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 73 4.1E-15 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS04020 bcdecb1335968fae344f62d250c57a43 239 PANTHER PTHR11751 12 75 3.4E-20 T 22-04-2016 HRM2_RS04020 bcdecb1335968fae344f62d250c57a43 239 PANTHER PTHR11751 93 116 3.4E-20 T 22-04-2016 HRM2_RS04020 bcdecb1335968fae344f62d250c57a43 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 4.5E-7 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS04020 bcdecb1335968fae344f62d250c57a43 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 4.5E-7 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS04020 bcdecb1335968fae344f62d250c57a43 239 Gene3D G3DSA:1.20.120.530 99 228 4.8E-26 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS04020 bcdecb1335968fae344f62d250c57a43 239 PANTHER PTHR11751:SF382 12 75 3.4E-20 T 22-04-2016 HRM2_RS04020 bcdecb1335968fae344f62d250c57a43 239 PANTHER PTHR11751:SF382 93 116 3.4E-20 T 22-04-2016 HRM2_RS04020 bcdecb1335968fae344f62d250c57a43 239 SMART SM00895 100 222 1.3E-20 T 22-04-2016 IPR011711 GntR, C-terminal HRM2_RS04020 bcdecb1335968fae344f62d250c57a43 239 SMART SM00345 14 73 1.1E-14 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS01030 cb38dfe2bfd72e724f3d09417404c939 571 Gene3D G3DSA:1.20.1270.20 152 171 1.4E-41 T 22-04-2016 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS01030 cb38dfe2bfd72e724f3d09417404c939 571 Gene3D G3DSA:1.20.1270.20 1 106 1.4E-41 T 22-04-2016 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS01030 cb38dfe2bfd72e724f3d09417404c939 571 PIRSF PIRSF000076 1 570 7.3E-249 T 22-04-2016 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS01030 cb38dfe2bfd72e724f3d09417404c939 571 Pfam PF03063 Prismane/CO dehydrogenase family 1 565 2.5E-171 T 22-04-2016 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS01030 cb38dfe2bfd72e724f3d09417404c939 571 Gene3D G3DSA:1.20.1270.20 172 244 2.5E-26 T 22-04-2016 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS01030 cb38dfe2bfd72e724f3d09417404c939 571 PANTHER PTHR30109 130 569 6.3E-265 T 22-04-2016 HRM2_RS01030 cb38dfe2bfd72e724f3d09417404c939 571 PANTHER PTHR30109 1 108 6.3E-265 T 22-04-2016 HRM2_RS01030 cb38dfe2bfd72e724f3d09417404c939 571 Gene3D G3DSA:3.40.50.2030 399 567 4.4E-73 T 22-04-2016 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS01030 cb38dfe2bfd72e724f3d09417404c939 571 Hamap MF_00069 Hydroxylamine reductase [hcp]. 1 569 22.974 T 22-04-2016 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS01030 cb38dfe2bfd72e724f3d09417404c939 571 Gene3D G3DSA:3.40.50.2030 247 398 2.6E-66 T 22-04-2016 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS01030 cb38dfe2bfd72e724f3d09417404c939 571 PANTHER PTHR30109:SF0 130 569 6.3E-265 T 22-04-2016 HRM2_RS01030 cb38dfe2bfd72e724f3d09417404c939 571 PANTHER PTHR30109:SF0 1 108 6.3E-265 T 22-04-2016 HRM2_RS01030 cb38dfe2bfd72e724f3d09417404c939 571 SUPERFAMILY SSF56821 1 568 8.77E-200 T 22-04-2016 IPR011254 Prismane-like GO:0003824|GO:0016491|GO:0055114 HRM2_RS01030 cb38dfe2bfd72e724f3d09417404c939 571 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 1 567 2.3E-222 T 22-04-2016 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS22285 837289d8aa5dbeaf762e52c7f0c949b7 668 Gene3D G3DSA:2.170.130.10 55 167 4.2E-32 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 HRM2_RS22285 837289d8aa5dbeaf762e52c7f0c949b7 668 SUPERFAMILY SSF56935 46 666 8.55E-103 T 22-04-2016 HRM2_RS22285 837289d8aa5dbeaf762e52c7f0c949b7 668 Pfam PF07715 TonB-dependent Receptor Plug Domain 57 165 7.5E-21 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 HRM2_RS22285 837289d8aa5dbeaf762e52c7f0c949b7 668 PANTHER PTHR32552 4 440 2.1E-37 T 22-04-2016 HRM2_RS22285 837289d8aa5dbeaf762e52c7f0c949b7 668 PANTHER PTHR32552 456 668 2.1E-37 T 22-04-2016 HRM2_RS22285 837289d8aa5dbeaf762e52c7f0c949b7 668 Pfam PF00593 TonB dependent receptor 410 666 2.1E-23 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 HRM2_RS22285 837289d8aa5dbeaf762e52c7f0c949b7 668 Gene3D G3DSA:2.40.170.20 168 666 1.8E-62 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 HRM2_RS18740 dc87e71f1e1d4ffa0421fbe92c804c26 409 Gene3D G3DSA:1.20.1250.20 14 208 3.5E-14 T 22-04-2016 HRM2_RS18740 dc87e71f1e1d4ffa0421fbe92c804c26 409 Gene3D G3DSA:1.20.1250.20 223 403 3.1E-8 T 22-04-2016 HRM2_RS18740 dc87e71f1e1d4ffa0421fbe92c804c26 409 SUPERFAMILY SSF103473 15 404 5.49E-34 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS18740 dc87e71f1e1d4ffa0421fbe92c804c26 409 Pfam PF05977 Transmembrane secretion effector 12 397 1.1E-24 T 22-04-2016 IPR010290 Transmembrane secretion effector HRM2_RS18740 dc87e71f1e1d4ffa0421fbe92c804c26 409 PANTHER PTHR23513 1 403 3.5E-59 T 22-04-2016 HRM2_RS10435 08606a09a2fb083c2b1ce76cf861f7d4 624 Gene3D G3DSA:3.40.50.980 210 374 3.9E-35 T 22-04-2016 HRM2_RS10435 08606a09a2fb083c2b1ce76cf861f7d4 624 PANTHER PTHR24096 6 599 3.1E-204 T 22-04-2016 HRM2_RS10435 08606a09a2fb083c2b1ce76cf861f7d4 624 Pfam PF00501 AMP-binding enzyme 38 461 1.1E-78 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS10435 08606a09a2fb083c2b1ce76cf861f7d4 624 Pfam PF13193 AMP-binding enzyme C-terminal domain 471 546 3.4E-13 T 22-04-2016 IPR025110 AMP-binding enzyme C-terminal domain HRM2_RS10435 08606a09a2fb083c2b1ce76cf861f7d4 624 Gene3D G3DSA:3.30.300.30 458 557 2.6E-22 T 22-04-2016 HRM2_RS10435 08606a09a2fb083c2b1ce76cf861f7d4 624 Gene3D G3DSA:2.30.38.10 375 452 2.9E-18 T 22-04-2016 HRM2_RS10435 08606a09a2fb083c2b1ce76cf861f7d4 624 PANTHER PTHR24096:SF170 6 599 3.1E-204 T 22-04-2016 HRM2_RS10435 08606a09a2fb083c2b1ce76cf861f7d4 624 Gene3D G3DSA:3.40.50.980 28 209 1.6E-21 T 22-04-2016 HRM2_RS10435 08606a09a2fb083c2b1ce76cf861f7d4 624 SUPERFAMILY SSF56801 28 554 7.46E-116 T 22-04-2016 HRM2_RS10435 08606a09a2fb083c2b1ce76cf861f7d4 624 ProSitePatterns PS00455 Putative AMP-binding domain signature. 206 217 - T 22-04-2016 IPR020845 AMP-binding, conserved site HRM2_RS15390 793aa46e87fcc98ecd95f1db910168dc 137 PANTHER PTHR37478:SF1 1 134 6.7E-29 T 22-04-2016 HRM2_RS15390 793aa46e87fcc98ecd95f1db910168dc 137 PANTHER PTHR37478 1 134 6.7E-29 T 22-04-2016 HRM2_RS15390 793aa46e87fcc98ecd95f1db910168dc 137 Hamap MF_00674 UPF0251 protein . 2 101 23.569 T 22-04-2016 IPR002852 Uncharacterised protein family UPF0251 HRM2_RS15390 793aa46e87fcc98ecd95f1db910168dc 137 Pfam PF02001 Protein of unknown function DUF134 3 96 1.3E-22 T 22-04-2016 IPR002852 Uncharacterised protein family UPF0251 HRM2_RS15390 793aa46e87fcc98ecd95f1db910168dc 137 SUPERFAMILY SSF88659 34 78 2.62E-6 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS15390 793aa46e87fcc98ecd95f1db910168dc 137 Gene3D G3DSA:1.10.10.10 34 80 1.8E-7 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS14530 e621599e6d92fed4657a698eae4300eb 602 SMART SM00493 263 334 3.6E-7 T 22-04-2016 IPR006171 Toprim domain HRM2_RS14530 e621599e6d92fed4657a698eae4300eb 602 SUPERFAMILY SSF56731 114 427 2.49E-92 T 22-04-2016 HRM2_RS14530 e621599e6d92fed4657a698eae4300eb 602 Gene3D G3DSA:3.90.580.10 2 96 5.7E-38 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS14530 e621599e6d92fed4657a698eae4300eb 602 Pfam PF13155 Toprim-like 266 350 7.6E-18 T 22-04-2016 HRM2_RS14530 e621599e6d92fed4657a698eae4300eb 602 Hamap MF_00974 DNA primase [dnaG]. 2 589 27.245 T 22-04-2016 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 HRM2_RS14530 e621599e6d92fed4657a698eae4300eb 602 Pfam PF01807 CHC2 zinc finger 4 96 6.1E-36 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS14530 e621599e6d92fed4657a698eae4300eb 602 SUPERFAMILY SSF57783 1 96 1.45E-36 T 22-04-2016 HRM2_RS14530 e621599e6d92fed4657a698eae4300eb 602 Pfam PF08275 DNA primase catalytic core, N-terminal domain 125 256 3.2E-36 T 22-04-2016 IPR013264 DNA primase, catalytic core, N-terminal HRM2_RS14530 e621599e6d92fed4657a698eae4300eb 602 SMART SM00400 34 88 1.1E-32 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS14530 e621599e6d92fed4657a698eae4300eb 602 Gene3D G3DSA:3.90.980.10 114 244 5.9E-39 T 22-04-2016 IPR013264 DNA primase, catalytic core, N-terminal HRM2_RS14530 e621599e6d92fed4657a698eae4300eb 602 PIRSF PIRSF002811 1 600 6.5E-156 T 22-04-2016 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 HRM2_RS14530 e621599e6d92fed4657a698eae4300eb 602 Gene3D G3DSA:3.40.1360.10 245 367 7.7E-39 T 22-04-2016 HRM2_RS14530 e621599e6d92fed4657a698eae4300eb 602 Gene3D G3DSA:1.20.50.20 371 424 3.7E-4 T 22-04-2016 HRM2_RS14530 e621599e6d92fed4657a698eae4300eb 602 PANTHER PTHR30313 1 598 8.6E-133 T 22-04-2016 HRM2_RS14530 e621599e6d92fed4657a698eae4300eb 602 Pfam PF10410 DnaB-helicase binding domain of primase 370 423 1.6E-9 T 22-04-2016 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 HRM2_RS14530 e621599e6d92fed4657a698eae4300eb 602 TIGRFAM TIGR01391 dnaG: DNA primase 3 419 4.7E-131 T 22-04-2016 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 HRM2_RS24400 c9881e7798dce801727bde7d56c8efcd 302 PIRSF PIRSF000371 1 302 1.3E-99 T 22-04-2016 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 HRM2_RS24400 c9881e7798dce801727bde7d56c8efcd 302 ProSitePatterns PS01087 Radical activating enzymes signature. 19 40 - T 22-04-2016 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 HRM2_RS24400 c9881e7798dce801727bde7d56c8efcd 302 Pfam PF13353 4Fe-4S single cluster domain 18 180 9.8E-12 T 22-04-2016 HRM2_RS24400 c9881e7798dce801727bde7d56c8efcd 302 Gene3D G3DSA:3.30.70.20 52 106 7.6E-17 T 22-04-2016 HRM2_RS24400 c9881e7798dce801727bde7d56c8efcd 302 PANTHER PTHR30352 1 60 3.2E-86 T 22-04-2016 HRM2_RS24400 c9881e7798dce801727bde7d56c8efcd 302 PANTHER PTHR30352 104 299 3.2E-86 T 22-04-2016 HRM2_RS24400 c9881e7798dce801727bde7d56c8efcd 302 TIGRFAM TIGR02494 PFLE_PFLC: glycyl-radical enzyme activating protein 8 293 9.1E-102 T 22-04-2016 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 HRM2_RS24400 c9881e7798dce801727bde7d56c8efcd 302 Gene3D G3DSA:3.80.30.10 126 300 1.8E-54 T 22-04-2016 HRM2_RS24400 c9881e7798dce801727bde7d56c8efcd 302 SUPERFAMILY SSF102114 88 280 4.9E-18 T 22-04-2016 HRM2_RS24400 c9881e7798dce801727bde7d56c8efcd 302 PANTHER PTHR30352:SF4 1 60 3.2E-86 T 22-04-2016 HRM2_RS24400 c9881e7798dce801727bde7d56c8efcd 302 PANTHER PTHR30352:SF4 104 299 3.2E-86 T 22-04-2016 HRM2_RS24400 c9881e7798dce801727bde7d56c8efcd 302 SUPERFAMILY SSF54862 13 139 2.72E-20 T 22-04-2016 HRM2_RS24400 c9881e7798dce801727bde7d56c8efcd 302 Pfam PF04055 Radical SAM superfamily 26 233 1.1E-21 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS24400 c9881e7798dce801727bde7d56c8efcd 302 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 57 68 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS24400 c9881e7798dce801727bde7d56c8efcd 302 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 86 97 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS15145 bd93199880912cb84fabcea9899f571a 307 PANTHER PTHR21039 24 291 9.6E-71 T 22-04-2016 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15|UniPathway: UPA00031 HRM2_RS15145 bd93199880912cb84fabcea9899f571a 307 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 30 279 1.1E-56 T 22-04-2016 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15|UniPathway: UPA00031 HRM2_RS15145 bd93199880912cb84fabcea9899f571a 307 Gene3D G3DSA:3.20.20.140 34 294 6.4E-21 T 22-04-2016 HRM2_RS15145 bd93199880912cb84fabcea9899f571a 307 SUPERFAMILY SSF89550 31 293 6.41E-30 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 HRM2_RS15145 bd93199880912cb84fabcea9899f571a 307 Pfam PF02811 PHP domain 31 229 1.4E-7 T 22-04-2016 IPR004013 PHP domain GO:0003824 HRM2_RS07325 2d5d5991148521bb518244977a4d8e79 1127 Pfam PF04851 Type III restriction enzyme, res subunit 353 499 2.7E-33 T 22-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HRM2_RS07325 2d5d5991148521bb518244977a4d8e79 1127 SUPERFAMILY SSF52540 308 561 6.01E-32 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07325 2d5d5991148521bb518244977a4d8e79 1127 Gene3D G3DSA:3.40.50.300 350 511 5.6E-25 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07325 2d5d5991148521bb518244977a4d8e79 1127 Pfam PF00271 Helicase conserved C-terminal domain 608 712 2.1E-6 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS07325 2d5d5991148521bb518244977a4d8e79 1127 Pfam PF08463 EcoEI R protein C-terminal 961 1110 1.9E-17 T 22-04-2016 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 HRM2_RS07325 2d5d5991148521bb518244977a4d8e79 1127 SUPERFAMILY SSF52540 373 427 1.16E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07325 2d5d5991148521bb518244977a4d8e79 1127 SUPERFAMILY SSF52540 627 737 1.16E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07325 2d5d5991148521bb518244977a4d8e79 1127 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 233 313 1.8E-6 T 22-04-2016 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 HRM2_RS07325 2d5d5991148521bb518244977a4d8e79 1127 Pfam PF13643 Domain of unknown function (DUF4145) 28 110 2.0E-8 T 22-04-2016 IPR025285 Domain of unknown function DUF4145 HRM2_RS07325 2d5d5991148521bb518244977a4d8e79 1127 PANTHER PTHR30195 79 1120 2.3E-184 T 22-04-2016 HRM2_RS07325 2d5d5991148521bb518244977a4d8e79 1127 PANTHER PTHR30195:SF3 79 1120 2.3E-184 T 22-04-2016 HRM2_RS07325 2d5d5991148521bb518244977a4d8e79 1127 SMART SM00487 348 539 4.1E-13 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS07325 2d5d5991148521bb518244977a4d8e79 1127 Gene3D G3DSA:3.40.50.300 586 712 6.0E-12 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09310 c86444086f0e13c8e3d29c746e2e374c 228 PANTHER PTHR26402 1 221 1.2E-93 T 22-04-2016 HRM2_RS09310 c86444086f0e13c8e3d29c746e2e374c 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 221 1.3E-25 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HRM2_RS09310 c86444086f0e13c8e3d29c746e2e374c 228 PANTHER PTHR26402:SF578 1 221 1.2E-93 T 22-04-2016 HRM2_RS09310 c86444086f0e13c8e3d29c746e2e374c 228 SMART SM00862 146 221 5.2E-25 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HRM2_RS09310 c86444086f0e13c8e3d29c746e2e374c 228 Gene3D G3DSA:1.10.10.10 125 222 1.3E-32 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS09310 c86444086f0e13c8e3d29c746e2e374c 228 SMART SM00448 1 112 5.2E-37 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS09310 c86444086f0e13c8e3d29c746e2e374c 228 SUPERFAMILY SSF52172 1 118 2.28E-38 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS09310 c86444086f0e13c8e3d29c746e2e374c 228 Pfam PF00072 Response regulator receiver domain 4 113 7.0E-25 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS09310 c86444086f0e13c8e3d29c746e2e374c 228 SUPERFAMILY SSF46894 123 222 1.53E-30 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HRM2_RS09310 c86444086f0e13c8e3d29c746e2e374c 228 Gene3D G3DSA:3.40.50.2300 1 119 1.6E-36 T 22-04-2016 HRM2_RS12955 2ecbaf0c64c5f7d38def1eac7b6c80db 587 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 279 302 - T 22-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 HRM2_RS12955 2ecbaf0c64c5f7d38def1eac7b6c80db 587 Pfam PF00027 Cyclic nucleotide-binding domain 158 241 2.9E-18 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain HRM2_RS12955 2ecbaf0c64c5f7d38def1eac7b6c80db 587 PANTHER PTHR24362 267 526 3.9E-81 T 22-04-2016 HRM2_RS12955 2ecbaf0c64c5f7d38def1eac7b6c80db 587 Gene3D G3DSA:1.10.510.10 382 523 1.8E-41 T 22-04-2016 HRM2_RS12955 2ecbaf0c64c5f7d38def1eac7b6c80db 587 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 206 223 - T 22-04-2016 IPR018488 Cyclic nucleotide-binding, conserved site HRM2_RS12955 2ecbaf0c64c5f7d38def1eac7b6c80db 587 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 392 404 - T 22-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 HRM2_RS12955 2ecbaf0c64c5f7d38def1eac7b6c80db 587 SUPERFAMILY SSF56112 270 526 5.53E-75 T 22-04-2016 IPR011009 Protein kinase-like domain HRM2_RS12955 2ecbaf0c64c5f7d38def1eac7b6c80db 587 Pfam PF00069 Protein kinase domain 274 522 4.4E-57 T 22-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 HRM2_RS12955 2ecbaf0c64c5f7d38def1eac7b6c80db 587 PANTHER PTHR24362:SF160 267 526 3.9E-81 T 22-04-2016 HRM2_RS12955 2ecbaf0c64c5f7d38def1eac7b6c80db 587 SMART SM00100 139 259 1.5E-16 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain HRM2_RS12955 2ecbaf0c64c5f7d38def1eac7b6c80db 587 SMART SM00220 273 529 5.9E-66 T 22-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 HRM2_RS12955 2ecbaf0c64c5f7d38def1eac7b6c80db 587 PRINTS PR00103 cAMP-dependent protein kinase signature 160 174 3.5E-6 T 22-04-2016 HRM2_RS12955 2ecbaf0c64c5f7d38def1eac7b6c80db 587 PRINTS PR00103 cAMP-dependent protein kinase signature 175 189 3.5E-6 T 22-04-2016 HRM2_RS12955 2ecbaf0c64c5f7d38def1eac7b6c80db 587 PRINTS PR00103 cAMP-dependent protein kinase signature 204 213 3.5E-6 T 22-04-2016 HRM2_RS12955 2ecbaf0c64c5f7d38def1eac7b6c80db 587 PRINTS PR00103 cAMP-dependent protein kinase signature 216 227 3.5E-6 T 22-04-2016 HRM2_RS12955 2ecbaf0c64c5f7d38def1eac7b6c80db 587 SUPERFAMILY SSF51206 131 259 5.37E-28 T 22-04-2016 IPR018490 Cyclic nucleotide-binding-like HRM2_RS12955 2ecbaf0c64c5f7d38def1eac7b6c80db 587 Gene3D G3DSA:2.60.120.10 132 251 2.9E-31 T 22-04-2016 IPR014710 RmlC-like jelly roll fold HRM2_RS12955 2ecbaf0c64c5f7d38def1eac7b6c80db 587 Gene3D G3DSA:3.30.200.20 258 381 6.6E-33 T 22-04-2016 HRM2_RS14690 90b531467600806075587d621d453243 443 SUPERFAMILY SSF48179 204 298 2.11E-33 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HRM2_RS14690 90b531467600806075587d621d453243 443 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 205 296 7.6E-39 T 22-04-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 HRM2_RS14690 90b531467600806075587d621d453243 443 PANTHER PTHR11374:SF18 1 443 5.2E-243 T 22-04-2016 HRM2_RS14690 90b531467600806075587d621d453243 443 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 320 428 1.1E-29 T 22-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 HRM2_RS14690 90b531467600806075587d621d453243 443 SUPERFAMILY SSF52413 305 439 3.53E-36 T 22-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 HRM2_RS14690 90b531467600806075587d621d453243 443 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 187 6.4E-66 T 22-04-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 HRM2_RS14690 90b531467600806075587d621d453243 443 SMART SM00984 320 428 2.9E-47 T 22-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 HRM2_RS14690 90b531467600806075587d621d453243 443 PANTHER PTHR11374 1 443 5.2E-243 T 22-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 HRM2_RS14690 90b531467600806075587d621d453243 443 SUPERFAMILY SSF51735 1 194 1.0E-54 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS14690 90b531467600806075587d621d453243 443 PIRSF PIRSF500134 1 443 2.0E-188 T 22-04-2016 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|UniPathway: UPA00038 HRM2_RS14690 90b531467600806075587d621d453243 443 Gene3D G3DSA:3.40.50.720 1 206 4.2E-77 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS14690 90b531467600806075587d621d453243 443 Gene3D G3DSA:3.40.50.720 235 443 1.8E-70 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS14690 90b531467600806075587d621d453243 443 PIRSF PIRSF000124 1 443 2.1E-148 T 22-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 HRM2_RS14690 90b531467600806075587d621d453243 443 Gene3D G3DSA:1.20.5.100 207 233 3.5E-19 T 22-04-2016 HRM2_RS14690 90b531467600806075587d621d453243 443 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 424 1.5E-135 T 22-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 HRM2_RS21955 077a42b7cea351eedc00865d1f46e6ba 608 Gene3D G3DSA:3.30.870.10 297 338 1.6E-4 T 22-04-2016 HRM2_RS21955 077a42b7cea351eedc00865d1f46e6ba 608 SUPERFAMILY SSF56024 297 338 7.46E-6 T 22-04-2016 HRM2_RS13225 841903ed79c2766117251c9ca5693e67 324 SUPERFAMILY SSF53850 30 323 6.53E-52 T 22-04-2016 HRM2_RS13225 841903ed79c2766117251c9ca5693e67 324 Gene3D G3DSA:3.40.190.10 122 250 3.8E-31 T 22-04-2016 HRM2_RS13225 841903ed79c2766117251c9ca5693e67 324 Gene3D G3DSA:3.40.190.10 251 322 1.3E-32 T 22-04-2016 HRM2_RS13225 841903ed79c2766117251c9ca5693e67 324 Gene3D G3DSA:3.40.190.10 29 111 1.3E-32 T 22-04-2016 HRM2_RS13225 841903ed79c2766117251c9ca5693e67 324 Pfam PF16868 NMT1-like family 35 321 1.9E-57 T 22-04-2016 IPR011852 TRAP transporter solute receptor, TAXI family HRM2_RS13225 841903ed79c2766117251c9ca5693e67 324 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 6 321 1.7E-62 T 22-04-2016 IPR011852 TRAP transporter solute receptor, TAXI family HRM2_RS13225 841903ed79c2766117251c9ca5693e67 324 PANTHER PTHR30024:SF13 26 324 8.3E-46 T 22-04-2016 HRM2_RS13225 841903ed79c2766117251c9ca5693e67 324 PANTHER PTHR30024 26 324 8.3E-46 T 22-04-2016 HRM2_RS16930 04120e8173f9fef733e6f89f2d2f8b18 284 Gene3D G3DSA:3.30.450.20 4 124 2.1E-6 T 22-04-2016 HRM2_RS16930 04120e8173f9fef733e6f89f2d2f8b18 284 Gene3D G3DSA:1.10.10.10 224 273 4.5E-16 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS16930 04120e8173f9fef733e6f89f2d2f8b18 284 SUPERFAMILY SSF46894 212 273 1.67E-15 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HRM2_RS16930 04120e8173f9fef733e6f89f2d2f8b18 284 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 239 255 5.9E-10 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS16930 04120e8173f9fef733e6f89f2d2f8b18 284 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 225 239 5.9E-10 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS16930 04120e8173f9fef733e6f89f2d2f8b18 284 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 255 267 5.9E-10 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS16930 04120e8173f9fef733e6f89f2d2f8b18 284 ProSitePatterns PS00622 LuxR-type HTH domain signature. 239 266 - T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS16930 04120e8173f9fef733e6f89f2d2f8b18 284 SMART SM00421 222 279 3.7E-13 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS16930 04120e8173f9fef733e6f89f2d2f8b18 284 Pfam PF00196 Bacterial regulatory proteins, luxR family 224 273 4.0E-15 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS24015 3ad1f5133866108e08409c03924e2da9 197 Gene3D G3DSA:3.20.20.70 5 196 8.1E-34 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS24015 3ad1f5133866108e08409c03924e2da9 197 SUPERFAMILY SSF54631 55 196 3.63E-34 T 22-04-2016 HRM2_RS24015 3ad1f5133866108e08409c03924e2da9 197 SMART SM00116 149 197 1.1E-6 T 22-04-2016 IPR000644 CBS domain HRM2_RS24015 3ad1f5133866108e08409c03924e2da9 197 SMART SM00116 64 112 7.5E-6 T 22-04-2016 IPR000644 CBS domain HRM2_RS24015 3ad1f5133866108e08409c03924e2da9 197 Pfam PF00571 CBS domain 59 109 4.2E-13 T 22-04-2016 IPR000644 CBS domain HRM2_RS24015 3ad1f5133866108e08409c03924e2da9 197 Pfam PF00571 CBS domain 143 196 1.9E-14 T 22-04-2016 IPR000644 CBS domain HRM2_RS24015 3ad1f5133866108e08409c03924e2da9 197 PANTHER PTHR11911 31 114 3.7E-30 T 22-04-2016 HRM2_RS24015 3ad1f5133866108e08409c03924e2da9 197 PANTHER PTHR11911 141 196 3.7E-30 T 22-04-2016 HRM2_RS06620 bfa90b58989ec8bd5f75d2215e92e052 517 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 150 365 2.3E-71 T 22-04-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS06620 bfa90b58989ec8bd5f75d2215e92e052 517 PANTHER PTHR15184:SF3 1 487 3.4E-222 T 22-04-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS06620 bfa90b58989ec8bd5f75d2215e92e052 517 Gene3D G3DSA:3.40.50.300 95 372 6.2E-109 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06620 bfa90b58989ec8bd5f75d2215e92e052 517 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 372 495 3.4E-32 T 22-04-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS06620 bfa90b58989ec8bd5f75d2215e92e052 517 Gene3D G3DSA:2.40.30.20 11 92 4.7E-14 T 22-04-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS06620 bfa90b58989ec8bd5f75d2215e92e052 517 Gene3D G3DSA:1.20.150.20 376 497 2.0E-29 T 22-04-2016 HRM2_RS06620 bfa90b58989ec8bd5f75d2215e92e052 517 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 356 365 - T 22-04-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS06620 bfa90b58989ec8bd5f75d2215e92e052 517 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 12 490 3.6E-187 T 22-04-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS06620 bfa90b58989ec8bd5f75d2215e92e052 517 SUPERFAMILY SSF50615 15 92 1.46E-12 T 22-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS06620 bfa90b58989ec8bd5f75d2215e92e052 517 PANTHER PTHR15184 1 487 3.4E-222 T 22-04-2016 HRM2_RS06620 bfa90b58989ec8bd5f75d2215e92e052 517 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 2 506 40.28 T 22-04-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS06620 bfa90b58989ec8bd5f75d2215e92e052 517 SUPERFAMILY SSF52540 97 371 3.72E-98 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06620 bfa90b58989ec8bd5f75d2215e92e052 517 SUPERFAMILY SSF47917 377 497 3.34E-29 T 22-04-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS07360 7f8e9dbb81c18677d6e31291adbe3284 230 Pfam PF13672 Protein phosphatase 2C 11 210 3.8E-37 T 22-04-2016 HRM2_RS07360 7f8e9dbb81c18677d6e31291adbe3284 230 SUPERFAMILY SSF81606 19 229 1.83E-12 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 HRM2_RS07360 7f8e9dbb81c18677d6e31291adbe3284 230 Gene3D G3DSA:3.60.40.10 22 137 5.5E-5 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 HRM2_RS04055 d8213ec5ea069ea61bffd7b58af82ce7 224 Pfam PF13441 YMGG-like Gly-zipper 37 78 4.7E-9 T 22-04-2016 IPR027367 YMGG-like Gly-zipper HRM2_RS04440 8b47dcfbff2e8b6222a49f849ebd7782 406 Pfam PF00155 Aminotransferase class I and II 52 400 1.6E-40 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HRM2_RS04440 8b47dcfbff2e8b6222a49f849ebd7782 406 PANTHER PTHR13693 58 405 1.4E-113 T 22-04-2016 HRM2_RS04440 8b47dcfbff2e8b6222a49f849ebd7782 406 Gene3D G3DSA:3.90.1150.10 293 406 6.6E-26 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS04440 8b47dcfbff2e8b6222a49f849ebd7782 406 Gene3D G3DSA:3.40.640.10 70 292 1.3E-69 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS04440 8b47dcfbff2e8b6222a49f849ebd7782 406 SUPERFAMILY SSF53383 27 405 1.39E-83 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS00155 905fee2005ba34cc86c7431d2288b423 401 PIRSF PIRSF029172 1 401 5.9E-142 T 22-04-2016 IPR027020 Protein ynjB HRM2_RS00155 905fee2005ba34cc86c7431d2288b423 401 Pfam PF13416 Bacterial extracellular solute-binding protein 60 346 1.7E-22 T 22-04-2016 HRM2_RS00155 905fee2005ba34cc86c7431d2288b423 401 Gene3D G3DSA:3.40.190.10 185 317 2.6E-5 T 22-04-2016 HRM2_RS00155 905fee2005ba34cc86c7431d2288b423 401 SUPERFAMILY SSF53850 38 358 6.64E-30 T 22-04-2016 HRM2_RS00155 905fee2005ba34cc86c7431d2288b423 401 PANTHER PTHR30006:SF12 35 211 9.4E-108 T 22-04-2016 HRM2_RS00155 905fee2005ba34cc86c7431d2288b423 401 PANTHER PTHR30006:SF12 228 396 9.4E-108 T 22-04-2016 HRM2_RS00155 905fee2005ba34cc86c7431d2288b423 401 PANTHER PTHR30006 35 211 9.4E-108 T 22-04-2016 HRM2_RS00155 905fee2005ba34cc86c7431d2288b423 401 PANTHER PTHR30006 228 396 9.4E-108 T 22-04-2016 HRM2_RS00155 905fee2005ba34cc86c7431d2288b423 401 Gene3D G3DSA:3.40.190.10 37 153 6.5E-19 T 22-04-2016 HRM2_RS00155 905fee2005ba34cc86c7431d2288b423 401 Gene3D G3DSA:3.40.190.10 318 359 6.5E-19 T 22-04-2016 HRM2_RS11870 ca144ce42513cacbec00e5d1c69c11f7 369 Gene3D G3DSA:3.40.810.20 114 354 1.9E-42 T 22-04-2016 HRM2_RS11870 ca144ce42513cacbec00e5d1c69c11f7 369 Gene3D G3DSA:3.40.1080.10 4 102 5.4E-27 T 22-04-2016 HRM2_RS11870 ca144ce42513cacbec00e5d1c69c11f7 369 SUPERFAMILY SSF100950 112 356 5.3E-59 T 22-04-2016 HRM2_RS11870 ca144ce42513cacbec00e5d1c69c11f7 369 SUPERFAMILY SSF100950 12 143 3.81E-16 T 22-04-2016 HRM2_RS11870 ca144ce42513cacbec00e5d1c69c11f7 369 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 194 350 7.3E-60 T 22-04-2016 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain HRM2_RS11870 ca144ce42513cacbec00e5d1c69c11f7 369 PANTHER PTHR21432 15 353 7.4E-103 T 22-04-2016 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 HRM2_RS11870 ca144ce42513cacbec00e5d1c69c11f7 369 PANTHER PTHR21432:SF18 15 353 7.4E-103 T 22-04-2016 HRM2_RS11870 ca144ce42513cacbec00e5d1c69c11f7 369 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 4 103 6.0E-14 T 22-04-2016 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 HRM2_RS13270 2aa23819e6171bd8044699a543a9a80c 273 PANTHER PTHR21600:SF3 25 259 2.9E-55 T 22-04-2016 HRM2_RS13270 2aa23819e6171bd8044699a543a9a80c 273 Pfam PF04468 PSP1 C-terminal conserved region 61 146 6.5E-27 T 22-04-2016 IPR007557 PSP1, C-terminal HRM2_RS13270 2aa23819e6171bd8044699a543a9a80c 273 PANTHER PTHR21600 25 259 2.9E-55 T 22-04-2016 HRM2_RS11225 3f6791e007c2082e07714a441f65bc28 521 PANTHER PTHR11985 3 513 3.8E-220 T 22-04-2016 HRM2_RS11225 3f6791e007c2082e07714a441f65bc28 521 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 91 103 8.3E-26 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS11225 3f6791e007c2082e07714a441f65bc28 521 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 364 376 8.3E-26 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS11225 3f6791e007c2082e07714a441f65bc28 521 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 332 338 8.3E-26 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS11225 3f6791e007c2082e07714a441f65bc28 521 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 46 58 8.3E-26 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS11225 3f6791e007c2082e07714a441f65bc28 521 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 30 40 8.3E-26 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS11225 3f6791e007c2082e07714a441f65bc28 521 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 17 29 8.3E-26 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS11225 3f6791e007c2082e07714a441f65bc28 521 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 369 379 - T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS11225 3f6791e007c2082e07714a441f65bc28 521 Pfam PF01266 FAD dependent oxidoreductase 18 375 9.2E-46 T 22-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 HRM2_RS11225 3f6791e007c2082e07714a441f65bc28 521 Gene3D G3DSA:3.50.50.60 16 282 6.6E-41 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS11225 3f6791e007c2082e07714a441f65bc28 521 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 389 501 1.2E-21 T 22-04-2016 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS11225 3f6791e007c2082e07714a441f65bc28 521 SUPERFAMILY SSF51905 17 342 2.33E-36 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS18435 e2f76af18bdbc179a89ce6fc71004952 124 SUPERFAMILY SSF52172 4 124 2.13E-36 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS18435 e2f76af18bdbc179a89ce6fc71004952 124 Pfam PF00072 Response regulator receiver domain 7 119 2.0E-31 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18435 e2f76af18bdbc179a89ce6fc71004952 124 Gene3D G3DSA:3.40.50.2300 3 123 9.2E-38 T 22-04-2016 HRM2_RS18435 e2f76af18bdbc179a89ce6fc71004952 124 SMART SM00448 5 119 2.8E-35 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18435 e2f76af18bdbc179a89ce6fc71004952 124 PANTHER PTHR26402 5 124 3.3E-41 T 22-04-2016 HRM2_RS15660 051237e313e29cb80a9aa765b7c87217 345 Pfam PF01926 50S ribosome-binding GTPase 161 284 2.7E-23 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS15660 051237e313e29cb80a9aa765b7c87217 345 Hamap MF_01454 GTPase Obg [obg]. 2 329 47.492 T 22-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 HRM2_RS15660 051237e313e29cb80a9aa765b7c87217 345 SUPERFAMILY SSF82051 3 158 1.19E-53 T 22-04-2016 IPR006169 GTP1/OBG domain GO:0005525 HRM2_RS15660 051237e313e29cb80a9aa765b7c87217 345 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 161 324 2.1E-12 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HRM2_RS15660 051237e313e29cb80a9aa765b7c87217 345 PIRSF PIRSF002401 1 345 5.5E-134 T 22-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 HRM2_RS15660 051237e313e29cb80a9aa765b7c87217 345 Pfam PF01018 GTP1/OBG 3 158 2.5E-59 T 22-04-2016 IPR006169 GTP1/OBG domain GO:0005525 HRM2_RS15660 051237e313e29cb80a9aa765b7c87217 345 Gene3D G3DSA:3.40.50.300 160 336 5.2E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS15660 051237e313e29cb80a9aa765b7c87217 345 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 22-04-2016 IPR006074 GTP1/OBG, conserved site GO:0005525 HRM2_RS15660 051237e313e29cb80a9aa765b7c87217 345 SUPERFAMILY SSF52540 161 334 1.11E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS15660 051237e313e29cb80a9aa765b7c87217 345 Gene3D G3DSA:2.70.210.12 3 156 8.2E-57 T 22-04-2016 IPR006169 GTP1/OBG domain GO:0005525 HRM2_RS15660 051237e313e29cb80a9aa765b7c87217 345 PANTHER PTHR11702 2 341 2.2E-145 T 22-04-2016 HRM2_RS15660 051237e313e29cb80a9aa765b7c87217 345 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 1.3E-34 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS15660 051237e313e29cb80a9aa765b7c87217 345 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 1.3E-34 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS15660 051237e313e29cb80a9aa765b7c87217 345 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 1.3E-34 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS15660 051237e313e29cb80a9aa765b7c87217 345 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 1.3E-34 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS15660 051237e313e29cb80a9aa765b7c87217 345 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 327 2.2E-133 T 22-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 HRM2_RS15660 051237e313e29cb80a9aa765b7c87217 345 PANTHER PTHR11702:SF3 2 341 2.2E-145 T 22-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 HRM2_RS01200 26c17ff27c05d79139a8a548e7daa062 296 PANTHER PTHR30425 3 295 4.1E-114 T 22-04-2016 HRM2_RS01200 26c17ff27c05d79139a8a548e7daa062 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 289 2.2E-22 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS01200 26c17ff27c05d79139a8a548e7daa062 296 PANTHER PTHR30425:SF3 3 295 4.1E-114 T 22-04-2016 HRM2_RS01200 26c17ff27c05d79139a8a548e7daa062 296 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 8 288 4.0E-85 T 22-04-2016 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 HRM2_RS01200 26c17ff27c05d79139a8a548e7daa062 296 SUPERFAMILY SSF161098 11 284 2.94E-39 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS01200 26c17ff27c05d79139a8a548e7daa062 296 Gene3D G3DSA:1.10.3720.10 63 289 5.1E-43 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS03625 1f1cee963d11bfa5e4e23640af770a8e 114 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 84 108 - T 22-04-2016 IPR020458 Zinc finger, DksA/TraR C4-type conserved site HRM2_RS03625 1f1cee963d11bfa5e4e23640af770a8e 114 PANTHER PTHR33823 1 109 2.7E-12 T 22-04-2016 HRM2_RS03625 1f1cee963d11bfa5e4e23640af770a8e 114 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 79 110 1.5E-11 T 22-04-2016 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 HRM2_RS03625 1f1cee963d11bfa5e4e23640af770a8e 114 SUPERFAMILY SSF57716 81 110 8.55E-7 T 22-04-2016 HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 Pfam PF00672 HAMP domain 168 236 2.8E-11 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 PANTHER PTHR24423 665 826 1.8E-164 T 22-04-2016 HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 PANTHER PTHR24423 1 24 1.8E-164 T 22-04-2016 HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 PANTHER PTHR24423 245 528 1.8E-164 T 22-04-2016 HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 SMART SM00387 385 501 8.4E-39 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 SUPERFAMILY SSF158472 188 237 4.97E-7 T 22-04-2016 HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 SMART SM00304 187 240 2.6E-10 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 Gene3D G3DSA:3.40.50.2300 666 789 4.6E-42 T 22-04-2016 HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 SUPERFAMILY SSF47384 263 339 3.53E-21 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 SMART SM00448 666 783 2.9E-35 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 SMART SM00448 519 637 3.5E-24 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 440 1.0E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 479 1.0E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 PRINTS PR00344 Bacterial sensor protein C-terminal signature 485 498 1.0E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 454 1.0E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 Pfam PF01627 Hpt domain 842 919 3.4E-9 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 SUPERFAMILY SSF47226 805 927 9.81E-26 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 PANTHER PTHR24423:SF382 665 826 1.8E-164 T 22-04-2016 HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 PANTHER PTHR24423:SF382 1 24 1.8E-164 T 22-04-2016 HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 PANTHER PTHR24423:SF382 245 528 1.8E-164 T 22-04-2016 HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 Gene3D G3DSA:3.30.565.10 339 501 4.2E-47 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 Pfam PF17152 Periplasmic sensor domain 42 149 4.2E-16 T 22-04-2016 IPR033417 Periplasmic sensor domain CHASE8 UniPathway: UPA00599 HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 Pfam PF00072 Response regulator receiver domain 522 635 1.9E-20 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 Pfam PF00072 Response regulator receiver domain 668 783 2.7E-25 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 SUPERFAMILY SSF55874 327 497 1.44E-46 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 Gene3D G3DSA:1.10.287.130 265 334 5.2E-17 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 SMART SM00388 273 338 4.9E-26 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 SUPERFAMILY SSF52172 515 641 1.42E-30 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 Gene3D G3DSA:1.20.120.160 810 927 1.6E-26 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 Pfam PF00512 His Kinase A (phospho-acceptor) domain 273 338 1.1E-20 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 SUPERFAMILY SSF52172 666 789 4.98E-36 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 386 500 4.4E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS22290 3014ab26bc75d968b28990f4413b7361 941 Gene3D G3DSA:3.40.50.2300 517 647 9.1E-33 T 22-04-2016 HRM2_RS10445 af8774cf6eb9961e22739f77e6203fd3 213 Pfam PF03358 NADPH-dependent FMN reductase 2 148 4.4E-21 T 22-04-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 HRM2_RS10445 af8774cf6eb9961e22739f77e6203fd3 213 SUPERFAMILY SSF52218 2 149 1.06E-25 T 22-04-2016 IPR029039 Flavoprotein-like domain HRM2_RS10445 af8774cf6eb9961e22739f77e6203fd3 213 Gene3D G3DSA:3.40.50.360 2 161 4.9E-33 T 22-04-2016 IPR029039 Flavoprotein-like domain HRM2_RS10445 af8774cf6eb9961e22739f77e6203fd3 213 PANTHER PTHR10204 1 102 1.5E-19 T 22-04-2016 HRM2_RS10445 af8774cf6eb9961e22739f77e6203fd3 213 PANTHER PTHR10204:SF5 1 102 1.5E-19 T 22-04-2016 HRM2_RS09440 1d37d1c6e205dcd9e5afe26aa0db35cf 715 SMART SM00926 50 104 1.0E-9 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS09440 1d37d1c6e205dcd9e5afe26aa0db35cf 715 Pfam PF00384 Molybdopterin oxidoreductase 107 513 1.3E-38 T 22-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 HRM2_RS09440 1d37d1c6e205dcd9e5afe26aa0db35cf 715 SUPERFAMILY SSF53706 49 555 2.49E-105 T 22-04-2016 HRM2_RS09440 1d37d1c6e205dcd9e5afe26aa0db35cf 715 PANTHER PTHR11615:SF139 2 715 3.9E-66 T 22-04-2016 HRM2_RS09440 1d37d1c6e205dcd9e5afe26aa0db35cf 715 Gene3D G3DSA:3.40.50.740 109 181 9.4E-39 T 22-04-2016 HRM2_RS09440 1d37d1c6e205dcd9e5afe26aa0db35cf 715 Gene3D G3DSA:3.40.50.740 372 546 9.4E-39 T 22-04-2016 HRM2_RS09440 1d37d1c6e205dcd9e5afe26aa0db35cf 715 Gene3D G3DSA:2.20.25.90 49 108 2.7E-16 T 22-04-2016 HRM2_RS09440 1d37d1c6e205dcd9e5afe26aa0db35cf 715 Gene3D G3DSA:3.40.228.10 199 371 1.9E-39 T 22-04-2016 HRM2_RS09440 1d37d1c6e205dcd9e5afe26aa0db35cf 715 Gene3D G3DSA:2.40.40.20 576 715 2.3E-18 T 22-04-2016 HRM2_RS09440 1d37d1c6e205dcd9e5afe26aa0db35cf 715 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 54 103 1.1E-10 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS09440 1d37d1c6e205dcd9e5afe26aa0db35cf 715 SUPERFAMILY SSF50692 583 715 1.16E-18 T 22-04-2016 IPR009010 Aspartate decarboxylase-like domain HRM2_RS09440 1d37d1c6e205dcd9e5afe26aa0db35cf 715 PANTHER PTHR11615 2 715 3.9E-66 T 22-04-2016 HRM2_RS09440 1d37d1c6e205dcd9e5afe26aa0db35cf 715 Pfam PF01568 Molydopterin dinucleotide binding domain 621 701 9.9E-17 T 22-04-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 HRM2_RS25465 0fb208e4e61c02ee14b40c9c304fbbf0 143 ProSitePatterns PS00018 EF-hand calcium-binding domain. 88 100 - T 22-04-2016 IPR018247 EF-Hand 1, calcium-binding site HRM2_RS25465 0fb208e4e61c02ee14b40c9c304fbbf0 143 ProSitePatterns PS00018 EF-hand calcium-binding domain. 11 23 - T 22-04-2016 IPR018247 EF-Hand 1, calcium-binding site HRM2_RS25465 0fb208e4e61c02ee14b40c9c304fbbf0 143 ProSitePatterns PS00018 EF-hand calcium-binding domain. 39 51 - T 22-04-2016 IPR018247 EF-Hand 1, calcium-binding site HRM2_RS25465 0fb208e4e61c02ee14b40c9c304fbbf0 143 ProSitePatterns PS00018 EF-hand calcium-binding domain. 118 130 - T 22-04-2016 IPR018247 EF-Hand 1, calcium-binding site HRM2_RS25465 0fb208e4e61c02ee14b40c9c304fbbf0 143 Pfam PF13202 EF hand 112 133 9.8E-4 T 22-04-2016 IPR002048 EF-hand domain GO:0005509 HRM2_RS25465 0fb208e4e61c02ee14b40c9c304fbbf0 143 SUPERFAMILY SSF47473 3 134 7.12E-13 T 22-04-2016 IPR011992 EF-hand domain pair HRM2_RS25465 0fb208e4e61c02ee14b40c9c304fbbf0 143 Gene3D G3DSA:1.10.238.10 5 42 6.9E-6 T 22-04-2016 IPR011992 EF-hand domain pair HRM2_RS25465 0fb208e4e61c02ee14b40c9c304fbbf0 143 SMART SM00054 32 58 13.0 T 22-04-2016 IPR002048 EF-hand domain GO:0005509 HRM2_RS25465 0fb208e4e61c02ee14b40c9c304fbbf0 143 SMART SM00054 2 30 2.8 T 22-04-2016 IPR002048 EF-hand domain GO:0005509 HRM2_RS25465 0fb208e4e61c02ee14b40c9c304fbbf0 143 SMART SM00054 79 107 12.0 T 22-04-2016 IPR002048 EF-hand domain GO:0005509 HRM2_RS25465 0fb208e4e61c02ee14b40c9c304fbbf0 143 SMART SM00054 109 137 11.0 T 22-04-2016 IPR002048 EF-hand domain GO:0005509 HRM2_RS25465 0fb208e4e61c02ee14b40c9c304fbbf0 143 Pfam PF13499 EF-hand domain pair 33 102 4.4E-7 T 22-04-2016 IPR002048 EF-hand domain GO:0005509 HRM2_RS25465 0fb208e4e61c02ee14b40c9c304fbbf0 143 Gene3D G3DSA:1.10.238.10 43 140 2.3E-11 T 22-04-2016 IPR011992 EF-hand domain pair HRM2_RS15225 11b5db8f1be8ae5af78d53683773f609 117 Pfam PF00460 Flagella basal body rod protein 5 29 6.5E-5 T 22-04-2016 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 HRM2_RS15225 11b5db8f1be8ae5af78d53683773f609 117 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 71 114 4.3E-11 T 22-04-2016 IPR010930 Flagellar basal-body/hook protein, C-terminal domain HRM2_RS05790 48e69b4cf722ab4ec9f6a61550b630c6 59 Pfam PF13450 NAD(P)-binding Rossmann-like domain 13 47 1.3E-4 T 22-04-2016 HRM2_RS05790 48e69b4cf722ab4ec9f6a61550b630c6 59 Gene3D G3DSA:3.50.50.60 10 57 7.6E-14 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS05790 48e69b4cf722ab4ec9f6a61550b630c6 59 SUPERFAMILY SSF51971 9 56 5.18E-8 T 22-04-2016 HRM2_RS05790 48e69b4cf722ab4ec9f6a61550b630c6 59 PANTHER PTHR10742 8 59 2.2E-21 T 22-04-2016 HRM2_RS05790 48e69b4cf722ab4ec9f6a61550b630c6 59 PANTHER PTHR10742:SF263 8 59 2.2E-21 T 22-04-2016 HRM2_RS12595 c46b978a347ebd49eb918f7f6b06f07e 145 PANTHER PTHR23416:SF55 4 135 8.7E-38 T 22-04-2016 HRM2_RS12595 c46b978a347ebd49eb918f7f6b06f07e 145 SUPERFAMILY SSF51161 3 134 8.32E-33 T 22-04-2016 IPR011004 Trimeric LpxA-like HRM2_RS12595 c46b978a347ebd49eb918f7f6b06f07e 145 Gene3D G3DSA:2.160.10.10 40 137 3.6E-26 T 22-04-2016 HRM2_RS12595 c46b978a347ebd49eb918f7f6b06f07e 145 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 94 122 - T 22-04-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 HRM2_RS12595 c46b978a347ebd49eb918f7f6b06f07e 145 PIRSF PIRSF000441 1 142 1.8E-41 T 22-04-2016 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|UniPathway: UPA00136 HRM2_RS12595 c46b978a347ebd49eb918f7f6b06f07e 145 PANTHER PTHR23416 4 135 8.7E-38 T 22-04-2016 HRM2_RS12595 c46b978a347ebd49eb918f7f6b06f07e 145 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 41 78 4.6E-6 T 22-04-2016 IPR001451 Hexapeptide repeat HRM2_RS12595 c46b978a347ebd49eb918f7f6b06f07e 145 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 86 119 4.5E-7 T 22-04-2016 IPR001451 Hexapeptide repeat HRM2_RS14305 8d0f5e015c7b3348992e518578b4ec03 243 PANTHER PTHR10953:SF145 186 236 1.7E-58 T 22-04-2016 HRM2_RS14305 8d0f5e015c7b3348992e518578b4ec03 243 PANTHER PTHR10953:SF145 5 160 1.7E-58 T 22-04-2016 HRM2_RS14305 8d0f5e015c7b3348992e518578b4ec03 243 PANTHER PTHR10953 186 236 1.7E-58 T 22-04-2016 HRM2_RS14305 8d0f5e015c7b3348992e518578b4ec03 243 PANTHER PTHR10953 5 160 1.7E-58 T 22-04-2016 HRM2_RS14305 8d0f5e015c7b3348992e518578b4ec03 243 Gene3D G3DSA:3.40.50.720 222 242 2.4E-42 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS14305 8d0f5e015c7b3348992e518578b4ec03 243 Gene3D G3DSA:3.40.50.720 5 185 2.4E-42 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS14305 8d0f5e015c7b3348992e518578b4ec03 243 Pfam PF00899 ThiF family 13 241 1.7E-33 T 22-04-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 HRM2_RS14305 8d0f5e015c7b3348992e518578b4ec03 243 SUPERFAMILY SSF69572 4 242 1.31E-57 T 22-04-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 HRM2_RS15180 7d162deaf8d46c4a7c4459a53c2d805a 415 Pfam PF09861 Domain of unknown function (DUF2088) 7 199 1.4E-54 T 22-04-2016 IPR018657 Domain of unknown function DUF2088 HRM2_RS15180 7d162deaf8d46c4a7c4459a53c2d805a 415 PANTHER PTHR33171:SF3 1 396 1.4E-74 T 22-04-2016 HRM2_RS15180 7d162deaf8d46c4a7c4459a53c2d805a 415 PANTHER PTHR33171 1 396 1.4E-74 T 22-04-2016 HRM2_RS14375 53afc4db647057025e61b6babe308460 479 PANTHER PTHR22912 1 325 1.6E-38 T 22-04-2016 HRM2_RS14375 53afc4db647057025e61b6babe308460 479 Pfam PF04324 BFD-like [2Fe-2S] binding domain 398 448 1.6E-10 T 22-04-2016 IPR007419 BFD-like [2Fe-2S]-binding domain HRM2_RS14375 53afc4db647057025e61b6babe308460 479 PIRSF PIRSF037495 1 478 8.7E-117 T 22-04-2016 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 HRM2_RS14375 53afc4db647057025e61b6babe308460 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 119 137 3.2E-16 T 22-04-2016 HRM2_RS14375 53afc4db647057025e61b6babe308460 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 285 3.2E-16 T 22-04-2016 HRM2_RS14375 53afc4db647057025e61b6babe308460 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 301 323 3.2E-16 T 22-04-2016 HRM2_RS14375 53afc4db647057025e61b6babe308460 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 3.2E-16 T 22-04-2016 HRM2_RS14375 53afc4db647057025e61b6babe308460 479 PANTHER PTHR22912:SF141 1 325 1.6E-38 T 22-04-2016 HRM2_RS14375 53afc4db647057025e61b6babe308460 479 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 323 2.4E-25 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS14375 53afc4db647057025e61b6babe308460 479 Gene3D G3DSA:3.50.50.60 129 343 3.3E-20 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS14375 53afc4db647057025e61b6babe308460 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 270 284 1.1E-9 T 22-04-2016 HRM2_RS14375 53afc4db647057025e61b6babe308460 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 316 323 1.1E-9 T 22-04-2016 HRM2_RS14375 53afc4db647057025e61b6babe308460 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.1E-9 T 22-04-2016 HRM2_RS14375 53afc4db647057025e61b6babe308460 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 122 131 1.1E-9 T 22-04-2016 HRM2_RS14375 53afc4db647057025e61b6babe308460 479 SUPERFAMILY SSF51905 5 349 2.95E-33 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS14375 53afc4db647057025e61b6babe308460 479 Gene3D G3DSA:3.50.50.60 2 128 6.3E-18 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS02550 a38ecfa0be5c5f3d964ab2e7d0f078ef 556 SUPERFAMILY SSF109755 354 552 8.27E-33 T 22-04-2016 HRM2_RS02550 a38ecfa0be5c5f3d964ab2e7d0f078ef 556 Pfam PF02690 Na+/Pi-cotransporter 180 266 1.4E-12 T 22-04-2016 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: REACT_15518 HRM2_RS02550 a38ecfa0be5c5f3d964ab2e7d0f078ef 556 Pfam PF02690 Na+/Pi-cotransporter 16 151 2.4E-50 T 22-04-2016 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: REACT_15518 HRM2_RS02550 a38ecfa0be5c5f3d964ab2e7d0f078ef 556 Gene3D G3DSA:1.20.58.220 464 552 1.9E-9 T 22-04-2016 HRM2_RS02550 a38ecfa0be5c5f3d964ab2e7d0f078ef 556 Pfam PF01895 PhoU domain 363 448 1.2E-10 T 22-04-2016 IPR026022 PhoU domain HRM2_RS02550 a38ecfa0be5c5f3d964ab2e7d0f078ef 556 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 6 274 3.5E-67 T 22-04-2016 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 HRM2_RS02550 a38ecfa0be5c5f3d964ab2e7d0f078ef 556 PANTHER PTHR10010:SF26 1 458 9.6E-90 T 22-04-2016 HRM2_RS02550 a38ecfa0be5c5f3d964ab2e7d0f078ef 556 Gene3D G3DSA:1.20.58.220 354 455 1.2E-13 T 22-04-2016 HRM2_RS02550 a38ecfa0be5c5f3d964ab2e7d0f078ef 556 PANTHER PTHR10010 1 458 9.6E-90 T 22-04-2016 HRM2_RS14995 be1c3b53f893a1564082dc0e3e78d2c4 223 PANTHER PTHR35809 6 223 4.3E-69 T 22-04-2016 HRM2_RS14995 be1c3b53f893a1564082dc0e3e78d2c4 223 Pfam PF02666 Phosphatidylserine decarboxylase 52 219 7.8E-35 T 22-04-2016 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|UniPathway: UPA00558 HRM2_RS14995 be1c3b53f893a1564082dc0e3e78d2c4 223 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 34 219 2.6E-63 T 22-04-2016 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|UniPathway: UPA00558 HRM2_RS14995 be1c3b53f893a1564082dc0e3e78d2c4 223 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 16 223 34.78 T 22-04-2016 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|UniPathway: UPA00558 HRM2_RS18550 80a1e99c46a615d137f5061b8033934d 282 PANTHER PTHR22916 8 188 6.6E-55 T 22-04-2016 HRM2_RS18550 80a1e99c46a615d137f5061b8033934d 282 Gene3D G3DSA:3.90.550.10 8 229 4.4E-58 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS18550 80a1e99c46a615d137f5061b8033934d 282 SUPERFAMILY SSF53448 8 217 2.2E-57 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS18550 80a1e99c46a615d137f5061b8033934d 282 Pfam PF00535 Glycosyl transferase family 2 11 161 1.2E-35 T 22-04-2016 IPR001173 Glycosyltransferase 2-like HRM2_RS10180 aedcd936b5a921ddc6f4b869f09ee8fc 452 Pfam PF00072 Response regulator receiver domain 4 113 1.1E-22 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS10180 aedcd936b5a921ddc6f4b869f09ee8fc 452 Pfam PF02954 Bacterial regulatory protein, Fis family 403 426 3.1E-5 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS10180 aedcd936b5a921ddc6f4b869f09ee8fc 452 PANTHER PTHR32071 1 452 1.0E-180 T 22-04-2016 HRM2_RS10180 aedcd936b5a921ddc6f4b869f09ee8fc 452 SMART SM00448 2 113 5.0E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS10180 aedcd936b5a921ddc6f4b869f09ee8fc 452 Pfam PF00158 Sigma-54 interaction domain 142 308 2.2E-68 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS10180 aedcd936b5a921ddc6f4b869f09ee8fc 452 SUPERFAMILY SSF52540 142 383 3.34E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10180 aedcd936b5a921ddc6f4b869f09ee8fc 452 SUPERFAMILY SSF52172 2 185 7.4E-38 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS10180 aedcd936b5a921ddc6f4b869f09ee8fc 452 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 228 243 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS10180 aedcd936b5a921ddc6f4b869f09ee8fc 452 SUPERFAMILY SSF46689 355 443 1.03E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS10180 aedcd936b5a921ddc6f4b869f09ee8fc 452 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 355 364 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS10180 aedcd936b5a921ddc6f4b869f09ee8fc 452 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 166 179 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS10180 aedcd936b5a921ddc6f4b869f09ee8fc 452 Gene3D G3DSA:1.10.10.60 370 443 2.4E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS10180 aedcd936b5a921ddc6f4b869f09ee8fc 452 Gene3D G3DSA:3.40.50.300 139 314 4.6E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10180 aedcd936b5a921ddc6f4b869f09ee8fc 452 SMART SM00382 162 304 7.2E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS10180 aedcd936b5a921ddc6f4b869f09ee8fc 452 Gene3D G3DSA:1.10.8.60 315 369 1.9E-19 T 22-04-2016 HRM2_RS10180 aedcd936b5a921ddc6f4b869f09ee8fc 452 Gene3D G3DSA:3.40.50.2300 3 131 8.9E-32 T 22-04-2016 HRM2_RS06275 8661308b63c5c853badfc47e0a61cd22 581 SUPERFAMILY SSF56601 170 568 8.21E-99 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HRM2_RS06275 8661308b63c5c853badfc47e0a61cd22 581 PANTHER PTHR30627:SF1 1 580 2.7E-182 T 22-04-2016 HRM2_RS06275 8661308b63c5c853badfc47e0a61cd22 581 Gene3D G3DSA:3.90.1310.10 125 224 1.2E-24 T 22-04-2016 HRM2_RS06275 8661308b63c5c853badfc47e0a61cd22 581 Pfam PF03717 Penicillin-binding Protein dimerisation domain 56 201 4.3E-14 T 22-04-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 HRM2_RS06275 8661308b63c5c853badfc47e0a61cd22 581 Pfam PF00905 Penicillin binding protein transpeptidase domain 244 551 6.5E-79 T 22-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 HRM2_RS06275 8661308b63c5c853badfc47e0a61cd22 581 SUPERFAMILY SSF56519 52 216 6.8E-35 T 22-04-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 HRM2_RS06275 8661308b63c5c853badfc47e0a61cd22 581 Gene3D G3DSA:3.40.710.10 225 561 2.4E-97 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HRM2_RS06275 8661308b63c5c853badfc47e0a61cd22 581 PANTHER PTHR30627 1 580 2.7E-182 T 22-04-2016 HRM2_RS03010 df55e98ea4597e6834d4e67618ba2b5e 191 PANTHER PTHR33746:SF1 1 189 4.0E-74 T 22-04-2016 HRM2_RS03010 df55e98ea4597e6834d4e67618ba2b5e 191 PANTHER PTHR33746 1 189 4.0E-74 T 22-04-2016 HRM2_RS03010 df55e98ea4597e6834d4e67618ba2b5e 191 Gene3D G3DSA:1.20.1260.10 4 143 2.8E-43 T 22-04-2016 IPR012347 Ferritin-related HRM2_RS03010 df55e98ea4597e6834d4e67618ba2b5e 191 Gene3D G3DSA:2.20.28.10 148 190 8.2E-17 T 22-04-2016 IPR004039 Rubredoxin-type fold HRM2_RS03010 df55e98ea4597e6834d4e67618ba2b5e 191 SUPERFAMILY SSF47240 4 143 8.12E-32 T 22-04-2016 IPR009078 Ferritin-like superfamily HRM2_RS03010 df55e98ea4597e6834d4e67618ba2b5e 191 SUPERFAMILY SSF57802 148 190 2.17E-10 T 22-04-2016 HRM2_RS03010 df55e98ea4597e6834d4e67618ba2b5e 191 Pfam PF02915 Rubrerythrin 11 138 2.8E-25 T 22-04-2016 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 HRM2_RS00745 f1a92e2b913e80d3e9dd07df80fe6f32 448 Pfam PF00989 PAS fold 17 107 4.3E-6 T 22-04-2016 IPR013767 PAS fold GO:0006355 HRM2_RS00745 f1a92e2b913e80d3e9dd07df80fe6f32 448 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 167 180 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS00745 f1a92e2b913e80d3e9dd07df80fe6f32 448 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 430 448 1.42E-6 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS00745 f1a92e2b913e80d3e9dd07df80fe6f32 448 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 413 430 1.42E-6 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS00745 f1a92e2b913e80d3e9dd07df80fe6f32 448 Gene3D G3DSA:3.30.450.20 15 109 6.1E-9 T 22-04-2016 HRM2_RS00745 f1a92e2b913e80d3e9dd07df80fe6f32 448 Gene3D G3DSA:1.10.10.60 415 446 2.1E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS00745 f1a92e2b913e80d3e9dd07df80fe6f32 448 Gene3D G3DSA:1.10.8.60 317 390 7.5E-21 T 22-04-2016 HRM2_RS00745 f1a92e2b913e80d3e9dd07df80fe6f32 448 SMART SM00382 163 329 0.0034 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS00745 f1a92e2b913e80d3e9dd07df80fe6f32 448 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 357 366 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS00745 f1a92e2b913e80d3e9dd07df80fe6f32 448 SUPERFAMILY SSF52540 152 386 2.1E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00745 f1a92e2b913e80d3e9dd07df80fe6f32 448 Pfam PF02954 Bacterial regulatory protein, Fis family 415 446 1.1E-10 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS00745 f1a92e2b913e80d3e9dd07df80fe6f32 448 Gene3D G3DSA:3.40.50.300 146 316 3.9E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00745 f1a92e2b913e80d3e9dd07df80fe6f32 448 SUPERFAMILY SSF55785 11 112 5.32E-10 T 22-04-2016 IPR000014 PAS domain HRM2_RS00745 f1a92e2b913e80d3e9dd07df80fe6f32 448 PANTHER PTHR32071 146 446 1.0E-115 T 22-04-2016 HRM2_RS00745 f1a92e2b913e80d3e9dd07df80fe6f32 448 Pfam PF00158 Sigma-54 interaction domain 146 310 3.8E-56 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS00745 f1a92e2b913e80d3e9dd07df80fe6f32 448 SUPERFAMILY SSF46689 357 446 2.46E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS12075 7fa02cd0a7f0953e6f350577524544c7 281 Gene3D G3DSA:3.40.50.1000 5 86 6.2E-29 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS12075 7fa02cd0a7f0953e6f350577524544c7 281 Gene3D G3DSA:3.40.50.1000 175 247 6.2E-29 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS12075 7fa02cd0a7f0953e6f350577524544c7 281 Gene3D G3DSA:3.90.1070.10 105 174 5.7E-13 T 22-04-2016 HRM2_RS12075 7fa02cd0a7f0953e6f350577524544c7 281 Pfam PF05116 Sucrose-6F-phosphate phosphohydrolase 4 271 6.2E-51 T 22-04-2016 IPR006380 Sucrose-phosphatase, N-terminal HRM2_RS12075 7fa02cd0a7f0953e6f350577524544c7 281 SUPERFAMILY SSF56784 2 247 3.8E-29 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS12075 7fa02cd0a7f0953e6f350577524544c7 281 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 216 4.8E-18 T 22-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 HRM2_RS19310 5cb7af8fca3cc78da845649441e7fdfb 446 Pfam PF05199 GMC oxidoreductase 385 435 9.2E-12 T 22-04-2016 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 HRM2_RS19310 5cb7af8fca3cc78da845649441e7fdfb 446 Gene3D G3DSA:3.50.50.60 10 126 8.8E-55 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS19310 5cb7af8fca3cc78da845649441e7fdfb 446 Gene3D G3DSA:3.50.50.60 164 260 8.8E-55 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS19310 5cb7af8fca3cc78da845649441e7fdfb 446 Gene3D G3DSA:3.50.50.60 355 442 8.8E-55 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS19310 5cb7af8fca3cc78da845649441e7fdfb 446 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 10 32 2.2E-6 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HRM2_RS19310 5cb7af8fca3cc78da845649441e7fdfb 446 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 189 205 2.2E-6 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HRM2_RS19310 5cb7af8fca3cc78da845649441e7fdfb 446 PANTHER PTHR11552 11 435 8.3E-31 T 22-04-2016 HRM2_RS19310 5cb7af8fca3cc78da845649441e7fdfb 446 SUPERFAMILY SSF51905 389 443 1.8E-38 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS19310 5cb7af8fca3cc78da845649441e7fdfb 446 SUPERFAMILY SSF51905 10 268 1.8E-38 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS19310 5cb7af8fca3cc78da845649441e7fdfb 446 Pfam PF00732 GMC oxidoreductase 133 249 5.9E-15 T 22-04-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 HRM2_RS19310 5cb7af8fca3cc78da845649441e7fdfb 446 Pfam PF01494 FAD binding domain 10 38 4.7E-5 T 22-04-2016 IPR002938 FAD-binding domain GO:0071949 HRM2_RS02265 cc0687b5d8ff1788468efff925cf684b 65 PANTHER PTHR33343 1 64 2.6E-24 T 22-04-2016 HRM2_RS02265 cc0687b5d8ff1788468efff925cf684b 65 Pfam PF01632 Ribosomal protein L35 2 62 1.0E-23 T 22-04-2016 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS02265 cc0687b5d8ff1788468efff925cf684b 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 4.1E-19 T 22-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 HRM2_RS02265 cc0687b5d8ff1788468efff925cf684b 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 4.1E-19 T 22-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 HRM2_RS02265 cc0687b5d8ff1788468efff925cf684b 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 4.1E-19 T 22-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 HRM2_RS02265 cc0687b5d8ff1788468efff925cf684b 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 22-04-2016 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS02265 cc0687b5d8ff1788468efff925cf684b 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.587 T 22-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 HRM2_RS02265 cc0687b5d8ff1788468efff925cf684b 65 SUPERFAMILY SSF143034 2 63 4.58E-22 T 22-04-2016 HRM2_RS02265 cc0687b5d8ff1788468efff925cf684b 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 1.2E-24 T 22-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 HRM2_RS25075 db16c394259f828fbb4767a2afdc8063 701 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 361 698 33.488 T 22-04-2016 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 HRM2_RS25075 db16c394259f828fbb4767a2afdc8063 701 PANTHER PTHR21712:SF4 358 698 3.4E-105 T 22-04-2016 HRM2_RS25075 db16c394259f828fbb4767a2afdc8063 701 Gene3D G3DSA:3.40.50.720 163 258 7.8E-7 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS25075 db16c394259f828fbb4767a2afdc8063 701 Pfam PF02277 Phosphoribosyltransferase 364 696 7.7E-123 T 22-04-2016 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 HRM2_RS25075 db16c394259f828fbb4767a2afdc8063 701 SUPERFAMILY SSF51735 128 286 3.94E-14 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS25075 db16c394259f828fbb4767a2afdc8063 701 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 365 696 2.5E-125 T 22-04-2016 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 HRM2_RS25075 db16c394259f828fbb4767a2afdc8063 701 PANTHER PTHR21712 358 698 3.4E-105 T 22-04-2016 HRM2_RS25075 db16c394259f828fbb4767a2afdc8063 701 SUPERFAMILY SSF52733 361 697 2.88E-106 T 22-04-2016 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 HRM2_RS25075 db16c394259f828fbb4767a2afdc8063 701 Gene3D G3DSA:1.10.1610.10 357 420 6.0E-28 T 22-04-2016 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 HRM2_RS25075 db16c394259f828fbb4767a2afdc8063 701 Gene3D G3DSA:3.40.50.10210 421 677 8.7E-101 T 22-04-2016 HRM2_RS25075 db16c394259f828fbb4767a2afdc8063 701 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 121 4.6E-18 T 22-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 HRM2_RS25075 db16c394259f828fbb4767a2afdc8063 701 Gene3D G3DSA:3.90.180.10 3 162 1.2E-40 T 22-04-2016 IPR011032 GroES-like HRM2_RS25075 db16c394259f828fbb4767a2afdc8063 701 SUPERFAMILY SSF50129 4 160 4.09E-35 T 22-04-2016 IPR011032 GroES-like HRM2_RS17260 3c082aab730e8feebaf63549fbe0ffe8 286 SUPERFAMILY SSF161098 4 276 4.32E-53 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS17260 3c082aab730e8feebaf63549fbe0ffe8 286 PANTHER PTHR30193:SF10 1 286 1.4E-82 T 22-04-2016 HRM2_RS17260 3c082aab730e8feebaf63549fbe0ffe8 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 276 1.7E-13 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS17260 3c082aab730e8feebaf63549fbe0ffe8 286 PANTHER PTHR30193 1 286 1.4E-82 T 22-04-2016 HRM2_RS17260 3c082aab730e8feebaf63549fbe0ffe8 286 Gene3D G3DSA:1.10.3720.10 3 274 3.3E-50 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS01320 c0df706baac87e339c39b7dc53f62dfc 644 SUPERFAMILY SSF63882 11 173 1.7E-37 T 22-04-2016 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 HRM2_RS01320 c0df706baac87e339c39b7dc53f62dfc 644 Pfam PF12727 PBP superfamily domain 428 617 3.0E-66 T 22-04-2016 IPR024370 PBP domain HRM2_RS01320 c0df706baac87e339c39b7dc53f62dfc 644 Gene3D G3DSA:3.40.980.10 162 332 3.4E-47 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS01320 c0df706baac87e339c39b7dc53f62dfc 644 Pfam PF00994 Probable molybdopterin binding domain 179 318 1.7E-21 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS01320 c0df706baac87e339c39b7dc53f62dfc 644 SUPERFAMILY SSF63867 333 403 1.83E-13 T 22-04-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 HRM2_RS01320 c0df706baac87e339c39b7dc53f62dfc 644 PANTHER PTHR10192:SF16 5 418 1.5E-125 T 22-04-2016 HRM2_RS01320 c0df706baac87e339c39b7dc53f62dfc 644 Gene3D G3DSA:2.170.190.11 57 128 4.0E-12 T 22-04-2016 HRM2_RS01320 c0df706baac87e339c39b7dc53f62dfc 644 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 175 315 2.2E-25 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS01320 c0df706baac87e339c39b7dc53f62dfc 644 Gene3D G3DSA:3.90.105.10 129 161 3.7E-11 T 22-04-2016 HRM2_RS01320 c0df706baac87e339c39b7dc53f62dfc 644 Gene3D G3DSA:3.40.190.10 497 623 8.3E-12 T 22-04-2016 HRM2_RS01320 c0df706baac87e339c39b7dc53f62dfc 644 SUPERFAMILY SSF53218 175 326 7.46E-35 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS01320 c0df706baac87e339c39b7dc53f62dfc 644 SMART SM00852 178 320 3.9E-30 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS01320 c0df706baac87e339c39b7dc53f62dfc 644 PANTHER PTHR10192 5 418 1.5E-125 T 22-04-2016 HRM2_RS01320 c0df706baac87e339c39b7dc53f62dfc 644 Pfam PF03454 MoeA C-terminal region (domain IV) 338 402 8.5E-13 T 22-04-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 HRM2_RS01320 c0df706baac87e339c39b7dc53f62dfc 644 Pfam PF03453 MoeA N-terminal region (domain I and II) 13 164 2.9E-26 T 22-04-2016 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 HRM2_RS01320 c0df706baac87e339c39b7dc53f62dfc 644 SUPERFAMILY SSF53850 414 632 2.61E-16 T 22-04-2016 HRM2_RS01320 c0df706baac87e339c39b7dc53f62dfc 644 Gene3D G3DSA:2.40.340.10 335 405 3.7E-20 T 22-04-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 HRM2_RS03300 22cbb7ea4d06c5c2c0951c6de5b01445 380 Gene3D G3DSA:1.20.1250.20 2 186 1.0E-15 T 22-04-2016 HRM2_RS03300 22cbb7ea4d06c5c2c0951c6de5b01445 380 Gene3D G3DSA:1.20.1250.20 220 377 1.1E-10 T 22-04-2016 HRM2_RS03300 22cbb7ea4d06c5c2c0951c6de5b01445 380 SUPERFAMILY SSF103473 4 378 1.96E-39 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS03300 22cbb7ea4d06c5c2c0951c6de5b01445 380 Pfam PF07690 Major Facilitator Superfamily 15 343 6.0E-25 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS03300 22cbb7ea4d06c5c2c0951c6de5b01445 380 PANTHER PTHR23505:SF8 12 365 3.3E-28 T 22-04-2016 HRM2_RS03300 22cbb7ea4d06c5c2c0951c6de5b01445 380 PANTHER PTHR23505 12 365 3.3E-28 T 22-04-2016 HRM2_RS17255 35194ac6a8ac8593b1c2db5acbe1371d 263 Gene3D G3DSA:1.10.3720.10 9 261 3.9E-55 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS17255 35194ac6a8ac8593b1c2db5acbe1371d 263 PANTHER PTHR30193 6 257 3.0E-56 T 22-04-2016 HRM2_RS17255 35194ac6a8ac8593b1c2db5acbe1371d 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 259 3.5E-18 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS17255 35194ac6a8ac8593b1c2db5acbe1371d 263 SUPERFAMILY SSF161098 6 257 2.9E-54 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS17255 35194ac6a8ac8593b1c2db5acbe1371d 263 PANTHER PTHR30193:SF20 6 257 3.0E-56 T 22-04-2016 HRM2_RS22265 66eae19c59f432073afd5be8dfc65f19 681 PANTHER PTHR32552:SF25 469 574 1.2E-32 T 22-04-2016 HRM2_RS22265 66eae19c59f432073afd5be8dfc65f19 681 PANTHER PTHR32552:SF25 49 442 1.2E-32 T 22-04-2016 HRM2_RS22265 66eae19c59f432073afd5be8dfc65f19 681 Pfam PF07715 TonB-dependent Receptor Plug Domain 61 169 3.3E-21 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 HRM2_RS22265 66eae19c59f432073afd5be8dfc65f19 681 Pfam PF00593 TonB dependent receptor 409 655 1.5E-15 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 HRM2_RS22265 66eae19c59f432073afd5be8dfc65f19 681 PANTHER PTHR32552 469 574 1.2E-32 T 22-04-2016 HRM2_RS22265 66eae19c59f432073afd5be8dfc65f19 681 PANTHER PTHR32552 49 442 1.2E-32 T 22-04-2016 HRM2_RS22265 66eae19c59f432073afd5be8dfc65f19 681 SUPERFAMILY SSF56935 52 439 1.57E-88 T 22-04-2016 HRM2_RS22265 66eae19c59f432073afd5be8dfc65f19 681 SUPERFAMILY SSF56935 470 651 1.57E-88 T 22-04-2016 HRM2_RS22265 66eae19c59f432073afd5be8dfc65f19 681 Gene3D G3DSA:2.170.130.10 49 170 4.5E-32 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 HRM2_RS22265 66eae19c59f432073afd5be8dfc65f19 681 Gene3D G3DSA:2.40.170.20 171 680 2.5E-48 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 HRM2_RS12515 34d7dedb039f41a7058e7b1244c8370b 100 Gene3D G3DSA:1.10.260.40 17 67 7.8E-7 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS12515 34d7dedb039f41a7058e7b1244c8370b 100 SUPERFAMILY SSF47413 15 68 3.75E-6 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS12515 34d7dedb039f41a7058e7b1244c8370b 100 SMART SM00530 19 72 0.0072 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS12515 34d7dedb039f41a7058e7b1244c8370b 100 Pfam PF01381 Helix-turn-helix 21 67 2.5E-5 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS06195 47d8a9918d1966c268dd9061ee339031 334 Gene3D G3DSA:3.40.50.720 144 296 1.2E-63 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS06195 47d8a9918d1966c268dd9061ee339031 334 SUPERFAMILY SSF51735 121 296 1.69E-33 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS06195 47d8a9918d1966c268dd9061ee339031 334 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 7 330 1.3E-127 T 22-04-2016 IPR014188 Acrylyl-CoA reductase AcuI HRM2_RS06195 47d8a9918d1966c268dd9061ee339031 334 Gene3D G3DSA:3.90.180.10 16 143 7.0E-10 T 22-04-2016 IPR011032 GroES-like HRM2_RS06195 47d8a9918d1966c268dd9061ee339031 334 Pfam PF00107 Zinc-binding dehydrogenase 163 276 1.1E-13 T 22-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 HRM2_RS06195 47d8a9918d1966c268dd9061ee339031 334 SMART SM00829 14 328 4.3E-4 T 22-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 HRM2_RS06195 47d8a9918d1966c268dd9061ee339031 334 PANTHER PTHR11695:SF13 21 334 6.3E-138 T 22-04-2016 IPR014188 Acrylyl-CoA reductase AcuI HRM2_RS06195 47d8a9918d1966c268dd9061ee339031 334 PANTHER PTHR11695 21 334 6.3E-138 T 22-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 HRM2_RS06195 47d8a9918d1966c268dd9061ee339031 334 SUPERFAMILY SSF50129 7 144 3.04E-35 T 22-04-2016 IPR011032 GroES-like HRM2_RS20170 c5d3e6ee18b9a7fb9576ed086319f106 422 Gene3D G3DSA:3.30.70.270 71 157 6.8E-24 T 22-04-2016 HRM2_RS20170 c5d3e6ee18b9a7fb9576ed086319f106 422 SUPERFAMILY SSF56672 3 238 5.43E-68 T 22-04-2016 HRM2_RS20170 c5d3e6ee18b9a7fb9576ed086319f106 422 Pfam PF13438 Domain of unknown function (DUF4113) 370 420 9.0E-18 T 22-04-2016 IPR025188 Domain of unknown function DUF4113 HRM2_RS20170 c5d3e6ee18b9a7fb9576ed086319f106 422 Gene3D G3DSA:1.10.150.20 176 238 4.8E-9 T 22-04-2016 HRM2_RS20170 c5d3e6ee18b9a7fb9576ed086319f106 422 SUPERFAMILY SSF100879 243 344 2.88E-5 T 22-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS20170 c5d3e6ee18b9a7fb9576ed086319f106 422 Pfam PF00817 impB/mucB/samB family 7 151 9.8E-36 T 22-04-2016 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS20170 c5d3e6ee18b9a7fb9576ed086319f106 422 Pfam PF11799 impB/mucB/samB family C-terminal domain 243 354 6.6E-12 T 22-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS20170 c5d3e6ee18b9a7fb9576ed086319f106 422 PANTHER PTHR11076 1 400 1.3E-152 T 22-04-2016 HRM2_RS20170 c5d3e6ee18b9a7fb9576ed086319f106 422 Gene3D G3DSA:3.30.1490.100 245 356 2.9E-6 T 22-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS20170 c5d3e6ee18b9a7fb9576ed086319f106 422 PANTHER PTHR11076:SF40 1 400 1.3E-152 T 22-04-2016 HRM2_RS22455 b7a9695e9ab9a57fee64451ba43d36a2 872 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 577 587 - T 22-04-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site HRM2_RS22455 b7a9695e9ab9a57fee64451ba43d36a2 872 SUPERFAMILY SSF89260 72 188 2.48E-6 T 22-04-2016 HRM2_RS22455 b7a9695e9ab9a57fee64451ba43d36a2 872 SUPERFAMILY SSF52743 316 640 1.44E-76 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HRM2_RS22455 b7a9695e9ab9a57fee64451ba43d36a2 872 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 396 406 - T 22-04-2016 IPR022398 Peptidase S8, subtilisin, His-active site HRM2_RS22455 b7a9695e9ab9a57fee64451ba43d36a2 872 PANTHER PTHR10795:SF419 766 776 5.1E-57 T 22-04-2016 HRM2_RS22455 b7a9695e9ab9a57fee64451ba43d36a2 872 PANTHER PTHR10795:SF419 133 375 5.1E-57 T 22-04-2016 HRM2_RS22455 b7a9695e9ab9a57fee64451ba43d36a2 872 PANTHER PTHR10795:SF419 395 662 5.1E-57 T 22-04-2016 HRM2_RS22455 b7a9695e9ab9a57fee64451ba43d36a2 872 PRINTS PR00723 Subtilisin serine protease family (S8) signature 576 592 1.6E-16 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related HRM2_RS22455 b7a9695e9ab9a57fee64451ba43d36a2 872 PRINTS PR00723 Subtilisin serine protease family (S8) signature 392 405 1.6E-16 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related HRM2_RS22455 b7a9695e9ab9a57fee64451ba43d36a2 872 PRINTS PR00723 Subtilisin serine protease family (S8) signature 335 354 1.6E-16 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related HRM2_RS22455 b7a9695e9ab9a57fee64451ba43d36a2 872 Gene3D G3DSA:2.60.120.380 72 188 4.1E-10 T 22-04-2016 HRM2_RS22455 b7a9695e9ab9a57fee64451ba43d36a2 872 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 340 351 - T 22-04-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site HRM2_RS22455 b7a9695e9ab9a57fee64451ba43d36a2 872 PIRSF PIRSF037893 6 872 5.0E-210 T 22-04-2016 IPR017309 Peptidase S8A, subtilisin-related, proteobacteria HRM2_RS22455 b7a9695e9ab9a57fee64451ba43d36a2 872 Pfam PF00082 Subtilase family 336 609 1.6E-45 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HRM2_RS22455 b7a9695e9ab9a57fee64451ba43d36a2 872 Gene3D G3DSA:3.40.50.200 282 640 8.2E-85 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HRM2_RS22455 b7a9695e9ab9a57fee64451ba43d36a2 872 PANTHER PTHR10795 766 776 5.1E-57 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related HRM2_RS22455 b7a9695e9ab9a57fee64451ba43d36a2 872 PANTHER PTHR10795 133 375 5.1E-57 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related HRM2_RS22455 b7a9695e9ab9a57fee64451ba43d36a2 872 PANTHER PTHR10795 395 662 5.1E-57 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related HRM2_RS17525 d39808b3999b6b677ce77d1bbc067526 560 Gene3D G3DSA:3.40.50.300 14 109 1.1E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17525 d39808b3999b6b677ce77d1bbc067526 560 Gene3D G3DSA:3.40.50.300 146 291 1.1E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17525 d39808b3999b6b677ce77d1bbc067526 560 PANTHER PTHR19211 3 560 0.0 T 22-04-2016 HRM2_RS17525 d39808b3999b6b677ce77d1bbc067526 560 PANTHER PTHR19211:SF7 3 560 0.0 T 22-04-2016 HRM2_RS17525 d39808b3999b6b677ce77d1bbc067526 560 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 7 558 3.6E-280 T 22-04-2016 IPR022374 ABC transporter, ATP-binding protein, ChvD HRM2_RS17525 d39808b3999b6b677ce77d1bbc067526 560 Pfam PF00005 ABC transporter 25 196 2.3E-23 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS17525 d39808b3999b6b677ce77d1bbc067526 560 Pfam PF00005 ABC transporter 345 478 3.2E-22 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS17525 d39808b3999b6b677ce77d1bbc067526 560 Gene3D G3DSA:3.40.50.300 327 549 8.1E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17525 d39808b3999b6b677ce77d1bbc067526 560 SMART SM00382 34 241 3.3E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS17525 d39808b3999b6b677ce77d1bbc067526 560 SMART SM00382 353 524 1.5E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS17525 d39808b3999b6b677ce77d1bbc067526 560 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS17525 d39808b3999b6b677ce77d1bbc067526 560 SUPERFAMILY SSF52540 330 533 1.58E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17525 d39808b3999b6b677ce77d1bbc067526 560 Pfam PF12848 ABC transporter 235 306 6.1E-12 T 22-04-2016 IPR032781 ABC-transporter extension domain HRM2_RS17525 d39808b3999b6b677ce77d1bbc067526 560 SUPERFAMILY SSF52540 14 241 5.33E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10405 2e5a200a38d8404619d47ffdb79fb6f6 380 SUPERFAMILY SSF53067 178 329 2.41E-16 T 22-04-2016 HRM2_RS10405 2e5a200a38d8404619d47ffdb79fb6f6 380 Gene3D G3DSA:3.30.420.40 4 187 4.3E-11 T 22-04-2016 HRM2_RS10405 2e5a200a38d8404619d47ffdb79fb6f6 380 SUPERFAMILY SSF53067 1 167 7.12E-29 T 22-04-2016 HRM2_RS10405 2e5a200a38d8404619d47ffdb79fb6f6 380 Gene3D G3DSA:3.30.420.40 188 306 2.4E-5 T 22-04-2016 HRM2_RS00615 df4b6d747073d039277f0f68e3ddb76b 843 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 52 262 7.6E-32 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS00615 df4b6d747073d039277f0f68e3ddb76b 843 Gene3D G3DSA:3.30.450.40 318 486 2.3E-5 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS00615 df4b6d747073d039277f0f68e3ddb76b 843 SMART SM00062 45 265 2.9E-24 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS00615 df4b6d747073d039277f0f68e3ddb76b 843 SUPERFAMILY SSF53850 52 263 6.85E-44 T 22-04-2016 HRM2_RS00615 df4b6d747073d039277f0f68e3ddb76b 843 SMART SM00388 620 689 5.5E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS00615 df4b6d747073d039277f0f68e3ddb76b 843 PANTHER PTHR24423 85 103 2.0E-65 T 22-04-2016 HRM2_RS00615 df4b6d747073d039277f0f68e3ddb76b 843 PANTHER PTHR24423 476 842 2.0E-65 T 22-04-2016 HRM2_RS00615 df4b6d747073d039277f0f68e3ddb76b 843 Gene3D G3DSA:3.30.565.10 690 837 5.0E-32 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS00615 df4b6d747073d039277f0f68e3ddb76b 843 Pfam PF00512 His Kinase A (phospho-acceptor) domain 620 686 2.0E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS00615 df4b6d747073d039277f0f68e3ddb76b 843 Pfam PF13185 GAF domain 337 478 2.4E-20 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS00615 df4b6d747073d039277f0f68e3ddb76b 843 SMART SM00387 731 839 1.8E-20 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS00615 df4b6d747073d039277f0f68e3ddb76b 843 SUPERFAMILY SSF55874 683 837 3.01E-30 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS00615 df4b6d747073d039277f0f68e3ddb76b 843 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 736 835 5.3E-12 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS00615 df4b6d747073d039277f0f68e3ddb76b 843 SUPERFAMILY SSF47384 614 689 3.92E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS00615 df4b6d747073d039277f0f68e3ddb76b 843 Gene3D G3DSA:1.10.287.130 615 685 2.0E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS00615 df4b6d747073d039277f0f68e3ddb76b 843 Gene3D G3DSA:3.40.190.10 45 131 1.1E-23 T 22-04-2016 HRM2_RS00615 df4b6d747073d039277f0f68e3ddb76b 843 Gene3D G3DSA:3.40.190.10 225 262 1.1E-23 T 22-04-2016 HRM2_RS00615 df4b6d747073d039277f0f68e3ddb76b 843 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 488 611 5.4E-11 T 22-04-2016 IPR000014 PAS domain HRM2_RS00615 df4b6d747073d039277f0f68e3ddb76b 843 SUPERFAMILY SSF55781 338 488 4.84E-7 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS00615 df4b6d747073d039277f0f68e3ddb76b 843 SUPERFAMILY SSF55785 479 603 1.12E-12 T 22-04-2016 IPR000014 PAS domain HRM2_RS00615 df4b6d747073d039277f0f68e3ddb76b 843 PRINTS PR00344 Bacterial sensor protein C-terminal signature 788 798 7.4E-9 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS00615 df4b6d747073d039277f0f68e3ddb76b 843 PRINTS PR00344 Bacterial sensor protein C-terminal signature 770 784 7.4E-9 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS00615 df4b6d747073d039277f0f68e3ddb76b 843 PRINTS PR00344 Bacterial sensor protein C-terminal signature 799 817 7.4E-9 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS00615 df4b6d747073d039277f0f68e3ddb76b 843 Gene3D G3DSA:3.30.450.20 487 603 2.5E-14 T 22-04-2016 HRM2_RS00615 df4b6d747073d039277f0f68e3ddb76b 843 PANTHER PTHR24423:SF497 85 103 2.0E-65 T 22-04-2016 HRM2_RS00615 df4b6d747073d039277f0f68e3ddb76b 843 PANTHER PTHR24423:SF497 476 842 2.0E-65 T 22-04-2016 HRM2_RS00615 df4b6d747073d039277f0f68e3ddb76b 843 Gene3D G3DSA:3.40.190.10 133 220 2.1E-8 T 22-04-2016 HRM2_RS20685 47fd837a9aa2b3801999c8109f5cd2dd 1041 SMART SM00839 661 913 4.0E-5 T 22-04-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 HRM2_RS20685 47fd837a9aa2b3801999c8109f5cd2dd 1041 SUPERFAMILY SSF53223 433 601 2.45E-6 T 22-04-2016 HRM2_RS20685 47fd837a9aa2b3801999c8109f5cd2dd 1041 SUPERFAMILY SSF51735 801 892 6.13E-16 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS20685 47fd837a9aa2b3801999c8109f5cd2dd 1041 SUPERFAMILY SSF51735 667 763 6.13E-16 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS20685 47fd837a9aa2b3801999c8109f5cd2dd 1041 PANTHER PTHR11606:SF9 661 1024 3.0E-85 T 22-04-2016 HRM2_RS20685 47fd837a9aa2b3801999c8109f5cd2dd 1041 PANTHER PTHR11606:SF9 276 616 3.0E-85 T 22-04-2016 HRM2_RS20685 47fd837a9aa2b3801999c8109f5cd2dd 1041 Gene3D G3DSA:3.40.50.720 665 883 3.1E-25 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS20685 47fd837a9aa2b3801999c8109f5cd2dd 1041 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 353 533 3.3E-15 T 22-04-2016 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 HRM2_RS20685 47fd837a9aa2b3801999c8109f5cd2dd 1041 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 665 877 2.1E-21 T 22-04-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 HRM2_RS20685 47fd837a9aa2b3801999c8109f5cd2dd 1041 PANTHER PTHR11606 661 1024 3.0E-85 T 22-04-2016 HRM2_RS20685 47fd837a9aa2b3801999c8109f5cd2dd 1041 PANTHER PTHR11606 276 616 3.0E-85 T 22-04-2016 HRM2_RS10440 0713902b3a2ab97966ea41b56fa92dea 357 PANTHER PTHR30217:SF9 158 294 6.8E-16 T 22-04-2016 HRM2_RS10440 0713902b3a2ab97966ea41b56fa92dea 357 PANTHER PTHR30217 158 294 6.8E-16 T 22-04-2016 HRM2_RS16175 8fd8074b74c0b9e5a9b65d56ea45e641 436 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 37 292 2.5E-36 T 22-04-2016 IPR017039 Virulence factor BrkB HRM2_RS16175 8fd8074b74c0b9e5a9b65d56ea45e641 436 Pfam PF03631 Virulence factor BrkB 42 296 6.4E-54 T 22-04-2016 IPR017039 Virulence factor BrkB HRM2_RS16175 8fd8074b74c0b9e5a9b65d56ea45e641 436 PANTHER PTHR30213:SF0 7 436 5.2E-84 T 22-04-2016 HRM2_RS16175 8fd8074b74c0b9e5a9b65d56ea45e641 436 PANTHER PTHR30213 7 436 5.2E-84 T 22-04-2016 HRM2_RS19770 67a7c38f2a35f81f894f657ab61731b4 368 Gene3D G3DSA:2.40.50.100 74 102 2.5E-13 T 22-04-2016 HRM2_RS19770 67a7c38f2a35f81f894f657ab61731b4 368 Gene3D G3DSA:2.40.50.100 178 208 2.5E-13 T 22-04-2016 HRM2_RS19770 67a7c38f2a35f81f894f657ab61731b4 368 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 74 283 2.8E-18 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain HRM2_RS19770 67a7c38f2a35f81f894f657ab61731b4 368 Gene3D G3DSA:1.20.1600.10 111 177 1.7E-5 T 22-04-2016 HRM2_RS19770 67a7c38f2a35f81f894f657ab61731b4 368 PANTHER PTHR30469 1 366 1.7E-64 T 22-04-2016 HRM2_RS19770 67a7c38f2a35f81f894f657ab61731b4 368 SUPERFAMILY SSF111369 62 284 1.57E-20 T 22-04-2016 HRM2_RS19770 67a7c38f2a35f81f894f657ab61731b4 368 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 45 363 4.0E-68 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 HRM2_RS19715 bee03193b94ed7ae28a96402f32420a6 228 Gene3D G3DSA:3.40.50.980 187 226 7.0E-8 T 22-04-2016 HRM2_RS19715 bee03193b94ed7ae28a96402f32420a6 228 PANTHER PTHR24096 18 226 1.8E-35 T 22-04-2016 HRM2_RS19715 bee03193b94ed7ae28a96402f32420a6 228 SUPERFAMILY SSF56801 14 226 3.66E-39 T 22-04-2016 HRM2_RS19715 bee03193b94ed7ae28a96402f32420a6 228 ProSitePatterns PS00455 Putative AMP-binding domain signature. 179 190 - T 22-04-2016 IPR020845 AMP-binding, conserved site HRM2_RS19715 bee03193b94ed7ae28a96402f32420a6 228 Gene3D G3DSA:3.40.50.980 15 186 6.4E-33 T 22-04-2016 HRM2_RS19715 bee03193b94ed7ae28a96402f32420a6 228 Pfam PF00501 AMP-binding enzyme 16 226 2.7E-30 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS21005 811aa27d7cec3e834e08d1b8058a9c82 109 SUPERFAMILY SSF54913 6 104 5.56E-30 T 22-04-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta HRM2_RS21005 811aa27d7cec3e834e08d1b8058a9c82 109 PANTHER PTHR35983 2 103 6.3E-34 T 22-04-2016 HRM2_RS21005 811aa27d7cec3e834e08d1b8058a9c82 109 Pfam PF02641 Uncharacterized ACR, COG1993 9 103 3.8E-34 T 22-04-2016 IPR003793 Domain of unknown function DUF190 HRM2_RS21005 811aa27d7cec3e834e08d1b8058a9c82 109 Gene3D G3DSA:3.30.70.120 1 106 1.4E-36 T 22-04-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal HRM2_RS08065 c71f740b4d81c4c04ab2bb98649cdf58 340 PANTHER PTHR23339 18 115 9.5E-16 T 22-04-2016 HRM2_RS08065 c71f740b4d81c4c04ab2bb98649cdf58 340 SUPERFAMILY SSF52799 4 144 2.58E-31 T 22-04-2016 IPR029021 Protein-tyrosine phosphatase-like HRM2_RS08065 c71f740b4d81c4c04ab2bb98649cdf58 340 Pfam PF00782 Dual specificity phosphatase, catalytic domain 25 144 3.3E-13 T 22-04-2016 IPR000340 Dual specificity phosphatase, catalytic domain GO:0006470|GO:0008138 HRM2_RS08065 c71f740b4d81c4c04ab2bb98649cdf58 340 SMART SM00195 5 145 6.2E-7 T 22-04-2016 IPR020422 Dual specificity protein phosphatase domain GO:0006470|GO:0008138 HRM2_RS08065 c71f740b4d81c4c04ab2bb98649cdf58 340 Gene3D G3DSA:3.90.190.10 6 146 6.1E-30 T 22-04-2016 IPR029021 Protein-tyrosine phosphatase-like HRM2_RS08065 c71f740b4d81c4c04ab2bb98649cdf58 340 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 92 102 - T 22-04-2016 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311|GO:0016791 HRM2_RS08065 c71f740b4d81c4c04ab2bb98649cdf58 340 SMART SM00404 56 145 5.3E-4 T 22-04-2016 IPR003595 Protein-tyrosine phosphatase, catalytic HRM2_RS15850 c52dd076ec237bf1a363a203ee0fa920 191 Pfam PF02508 Rnf-Nqr subunit, membrane protein 5 190 2.2E-55 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 HRM2_RS15850 c52dd076ec237bf1a363a203ee0fa920 191 PANTHER PTHR30335 2 191 4.8E-97 T 22-04-2016 HRM2_RS15850 c52dd076ec237bf1a363a203ee0fa920 191 Hamap MF_00459 Electron transport complex subunit RsxA [rsxA]. 2 191 24.111 T 22-04-2016 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 HRM2_RS15850 c52dd076ec237bf1a363a203ee0fa920 191 TIGRFAM TIGR01943 rnfA: electron transport complex, RnfABCDGE type, A subunit 3 191 1.5E-74 T 22-04-2016 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 HRM2_RS15850 c52dd076ec237bf1a363a203ee0fa920 191 PANTHER PTHR30335:SF0 2 191 4.8E-97 T 22-04-2016 HRM2_RS15850 c52dd076ec237bf1a363a203ee0fa920 191 PIRSF PIRSF006102 1 191 4.3E-53 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 HRM2_RS17815 e84d5ef24fe1b740152c6bfc8b581136 60 Pfam PF00327 Ribosomal protein L30p/L7e 5 55 1.4E-18 T 22-04-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain HRM2_RS17815 e84d5ef24fe1b740152c6bfc8b581136 60 Gene3D G3DSA:3.30.1390.20 3 60 8.8E-26 T 22-04-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain HRM2_RS17815 e84d5ef24fe1b740152c6bfc8b581136 60 PANTHER PTHR15892:SF2 1 60 5.8E-21 T 22-04-2016 HRM2_RS17815 e84d5ef24fe1b740152c6bfc8b581136 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 5 59 2.3E-25 T 22-04-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 HRM2_RS17815 e84d5ef24fe1b740152c6bfc8b581136 60 PANTHER PTHR15892 1 60 5.8E-21 T 22-04-2016 HRM2_RS17815 e84d5ef24fe1b740152c6bfc8b581136 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 2 59 18.84 T 22-04-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 HRM2_RS17815 e84d5ef24fe1b740152c6bfc8b581136 60 PIRSF PIRSF002211 1 60 2.1E-27 T 22-04-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 HRM2_RS17815 e84d5ef24fe1b740152c6bfc8b581136 60 SUPERFAMILY SSF55129 4 60 2.75E-20 T 22-04-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain HRM2_RS14545 afcc7d5d62c61944d5f392366e6ccce5 418 Pfam PF02080 TrkA-C domain 309 371 4.2E-10 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS14545 afcc7d5d62c61944d5f392366e6ccce5 418 Gene3D G3DSA:3.30.1490.20 112 171 2.0E-7 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HRM2_RS14545 afcc7d5d62c61944d5f392366e6ccce5 418 SUPERFAMILY SSF116726 300 374 9.16E-15 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS14545 afcc7d5d62c61944d5f392366e6ccce5 418 Gene3D G3DSA:3.30.470.20 172 276 2.2E-32 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS14545 afcc7d5d62c61944d5f392366e6ccce5 418 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 2 286 6.2E-77 T 22-04-2016 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 HRM2_RS14545 afcc7d5d62c61944d5f392366e6ccce5 418 SUPERFAMILY SSF56059 89 288 1.2E-45 T 22-04-2016 HRM2_RS14545 afcc7d5d62c61944d5f392366e6ccce5 418 Gene3D G3DSA:3.40.50.20 8 111 7.2E-18 T 22-04-2016 IPR016185 Pre-ATP-grasp domain HRM2_RS14545 afcc7d5d62c61944d5f392366e6ccce5 418 Pfam PF08443 RimK-like ATP-grasp domain 98 286 4.2E-58 T 22-04-2016 IPR013651 ATP-grasp fold, RimK-type HRM2_RS14545 afcc7d5d62c61944d5f392366e6ccce5 418 Gene3D G3DSA:3.30.70.1450 306 372 6.5E-14 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS14545 afcc7d5d62c61944d5f392366e6ccce5 418 PANTHER PTHR21621:SF0 1 301 1.3E-113 T 22-04-2016 HRM2_RS14545 afcc7d5d62c61944d5f392366e6ccce5 418 PANTHER PTHR21621 1 301 1.3E-113 T 22-04-2016 HRM2_RS11045 41fc952aeab53ecc92be225bfa9ad924 450 SMART SM00448 5 116 1.2E-35 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS11045 41fc952aeab53ecc92be225bfa9ad924 450 Pfam PF00072 Response regulator receiver domain 7 116 5.6E-29 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS11045 41fc952aeab53ecc92be225bfa9ad924 450 Gene3D G3DSA:1.10.10.60 397 444 3.6E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS11045 41fc952aeab53ecc92be225bfa9ad924 450 Gene3D G3DSA:3.40.50.2300 5 128 1.4E-36 T 22-04-2016 HRM2_RS11045 41fc952aeab53ecc92be225bfa9ad924 450 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 164 177 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS11045 41fc952aeab53ecc92be225bfa9ad924 450 Pfam PF00158 Sigma-54 interaction domain 142 306 3.5E-62 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS11045 41fc952aeab53ecc92be225bfa9ad924 450 SUPERFAMILY SSF46689 353 444 4.17E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS11045 41fc952aeab53ecc92be225bfa9ad924 450 SUPERFAMILY SSF52540 141 381 2.93E-65 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11045 41fc952aeab53ecc92be225bfa9ad924 450 SMART SM00382 160 303 2.2E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS11045 41fc952aeab53ecc92be225bfa9ad924 450 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 408 425 1.5E-8 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS11045 41fc952aeab53ecc92be225bfa9ad924 450 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 425 445 1.5E-8 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS11045 41fc952aeab53ecc92be225bfa9ad924 450 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 353 362 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS11045 41fc952aeab53ecc92be225bfa9ad924 450 Pfam PF02954 Bacterial regulatory protein, Fis family 402 442 1.1E-10 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS11045 41fc952aeab53ecc92be225bfa9ad924 450 PANTHER PTHR32071 6 450 1.5E-166 T 22-04-2016 HRM2_RS11045 41fc952aeab53ecc92be225bfa9ad924 450 SUPERFAMILY SSF52172 5 185 9.25E-42 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS11045 41fc952aeab53ecc92be225bfa9ad924 450 Gene3D G3DSA:1.10.8.60 313 387 1.4E-20 T 22-04-2016 HRM2_RS11045 41fc952aeab53ecc92be225bfa9ad924 450 Gene3D G3DSA:3.40.50.300 140 312 6.7E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS15655 4ded0572a34ca294fd546cdabc4c9fdf 84 PANTHER PTHR15893 1 82 1.1E-44 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS15655 4ded0572a34ca294fd546cdabc4c9fdf 84 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 84 27.895 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS15655 4ded0572a34ca294fd546cdabc4c9fdf 84 SUPERFAMILY SSF110324 2 82 2.65E-33 T 22-04-2016 HRM2_RS15655 4ded0572a34ca294fd546cdabc4c9fdf 84 Gene3D G3DSA:2.40.50.100 20 83 3.0E-31 T 22-04-2016 HRM2_RS15655 4ded0572a34ca294fd546cdabc4c9fdf 84 PRINTS PR00063 Ribosomal protein L27 signature 4 28 5.6E-38 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS15655 4ded0572a34ca294fd546cdabc4c9fdf 84 PRINTS PR00063 Ribosomal protein L27 signature 54 78 5.6E-38 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS15655 4ded0572a34ca294fd546cdabc4c9fdf 84 PRINTS PR00063 Ribosomal protein L27 signature 29 53 5.6E-38 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS15655 4ded0572a34ca294fd546cdabc4c9fdf 84 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 81 2.1E-36 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS15655 4ded0572a34ca294fd546cdabc4c9fdf 84 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 74 6.0E-15 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS15655 4ded0572a34ca294fd546cdabc4c9fdf 84 Pfam PF01016 Ribosomal L27 protein 3 81 8.1E-36 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS08440 47a55c8aba541e6f6b6bd46d7cd35798 117 Pfam PF01022 Bacterial regulatory protein, arsR family 42 87 1.2E-17 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HRM2_RS08440 47a55c8aba541e6f6b6bd46d7cd35798 117 SMART SM00418 35 113 4.0E-34 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HRM2_RS08440 47a55c8aba541e6f6b6bd46d7cd35798 117 SUPERFAMILY SSF46785 26 113 9.62E-29 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS08440 47a55c8aba541e6f6b6bd46d7cd35798 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 7.4E-21 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HRM2_RS08440 47a55c8aba541e6f6b6bd46d7cd35798 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 84 99 7.4E-21 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HRM2_RS08440 47a55c8aba541e6f6b6bd46d7cd35798 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 67 7.4E-21 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HRM2_RS08440 47a55c8aba541e6f6b6bd46d7cd35798 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 7.4E-21 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HRM2_RS08440 47a55c8aba541e6f6b6bd46d7cd35798 117 Gene3D G3DSA:1.10.10.10 10 116 3.2E-36 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS08440 47a55c8aba541e6f6b6bd46d7cd35798 117 PANTHER PTHR33154 16 116 1.3E-30 T 22-04-2016 HRM2_RS03640 16a63cf73481c840bf6347aae02b3b43 266 Pfam PF00809 Pterin binding enzyme 6 228 3.2E-26 T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 HRM2_RS03640 16a63cf73481c840bf6347aae02b3b43 266 Gene3D G3DSA:3.20.20.20 4 259 5.0E-81 T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 HRM2_RS03640 16a63cf73481c840bf6347aae02b3b43 266 SUPERFAMILY SSF51717 3 259 1.31E-71 T 22-04-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 HRM2_RS12825 2fde95202df0754a7704df03164f34f9 421 Gene3D G3DSA:2.120.10.30 23 150 3.1E-7 T 22-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like HRM2_RS12825 2fde95202df0754a7704df03164f34f9 421 SUPERFAMILY SSF82171 351 364 2.16E-12 T 22-04-2016 HRM2_RS12825 2fde95202df0754a7704df03164f34f9 421 SUPERFAMILY SSF82171 32 313 2.16E-12 T 22-04-2016 HRM2_RS12825 2fde95202df0754a7704df03164f34f9 421 Gene3D G3DSA:2.120.10.30 151 315 1.7E-9 T 22-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like HRM2_RS12825 2fde95202df0754a7704df03164f34f9 421 Gene3D G3DSA:2.120.10.30 351 404 1.7E-9 T 22-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like HRM2_RS18990 41f1b8be2587ae5d2fcb441e339a66cc 430 Gene3D G3DSA:1.10.230.10 282 374 6.6E-36 T 22-04-2016 IPR016143 Citrate synthase-like, small alpha subdomain HRM2_RS18990 41f1b8be2587ae5d2fcb441e339a66cc 430 ProSitePatterns PS00480 Citrate synthase signature. 304 316 - T 22-04-2016 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 UniPathway: UPA00223 HRM2_RS18990 41f1b8be2587ae5d2fcb441e339a66cc 430 PANTHER PTHR11739 23 430 2.3E-176 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 HRM2_RS18990 41f1b8be2587ae5d2fcb441e339a66cc 430 Gene3D G3DSA:1.10.580.10 54 281 2.1E-86 T 22-04-2016 IPR016142 Citrate synthase-like, large alpha subdomain UniPathway: UPA00223 HRM2_RS18990 41f1b8be2587ae5d2fcb441e339a66cc 430 PRINTS PR00143 Citrate synthase signature 360 376 1.28E-47 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 HRM2_RS18990 41f1b8be2587ae5d2fcb441e339a66cc 430 PRINTS PR00143 Citrate synthase signature 380 394 1.28E-47 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 HRM2_RS18990 41f1b8be2587ae5d2fcb441e339a66cc 430 PRINTS PR00143 Citrate synthase signature 297 317 1.28E-47 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 HRM2_RS18990 41f1b8be2587ae5d2fcb441e339a66cc 430 PRINTS PR00143 Citrate synthase signature 165 178 1.28E-47 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 HRM2_RS18990 41f1b8be2587ae5d2fcb441e339a66cc 430 PRINTS PR00143 Citrate synthase signature 241 269 1.28E-47 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 HRM2_RS18990 41f1b8be2587ae5d2fcb441e339a66cc 430 PRINTS PR00143 Citrate synthase signature 219 234 1.28E-47 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 HRM2_RS18990 41f1b8be2587ae5d2fcb441e339a66cc 430 Pfam PF00285 Citrate synthase, C-terminal domain 48 412 2.7E-127 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 HRM2_RS18990 41f1b8be2587ae5d2fcb441e339a66cc 430 PIRSF PIRSF001369 40 430 3.2E-140 T 22-04-2016 IPR024176 Citrate synthase, bacterial-type UniPathway: UPA00223 HRM2_RS18990 41f1b8be2587ae5d2fcb441e339a66cc 430 SUPERFAMILY SSF48256 7 429 8.77E-146 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 HRM2_RS18990 41f1b8be2587ae5d2fcb441e339a66cc 430 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 17 420 2.2E-154 T 22-04-2016 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 UniPathway: UPA00223 HRM2_RS19280 d3f3631b8b66ce3a71712287a782894d 219 Gene3D G3DSA:3.30.1020.10 161 218 9.0E-15 T 22-04-2016 HRM2_RS19280 d3f3631b8b66ce3a71712287a782894d 219 PANTHER PTHR10681 7 217 5.5E-55 T 22-04-2016 HRM2_RS19280 d3f3631b8b66ce3a71712287a782894d 219 Hamap MF_00401 Peroxiredoxin. 9 217 46.173 T 22-04-2016 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 HRM2_RS19280 d3f3631b8b66ce3a71712287a782894d 219 Gene3D G3DSA:3.40.30.10 11 160 7.8E-52 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS19280 d3f3631b8b66ce3a71712287a782894d 219 Pfam PF00578 AhpC/TSA family 12 139 4.3E-26 T 22-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 HRM2_RS19280 d3f3631b8b66ce3a71712287a782894d 219 PIRSF PIRSF000239 4 219 1.1E-71 T 22-04-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15 HRM2_RS19280 d3f3631b8b66ce3a71712287a782894d 219 SUPERFAMILY SSF52833 7 217 9.08E-58 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS15770 65e6d627c8a3f37dd1a40538f298bbc4 264 Gene3D G3DSA:3.90.470.20 72 167 2.4E-16 T 22-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 HRM2_RS15770 65e6d627c8a3f37dd1a40538f298bbc4 264 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 160 224 4.2E-10 T 22-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 HRM2_RS15770 65e6d627c8a3f37dd1a40538f298bbc4 264 SUPERFAMILY SSF56214 159 257 3.53E-14 T 22-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 HRM2_RS15770 65e6d627c8a3f37dd1a40538f298bbc4 264 SUPERFAMILY SSF56214 58 149 2.62E-14 T 22-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 HRM2_RS15770 65e6d627c8a3f37dd1a40538f298bbc4 264 Gene3D G3DSA:3.90.470.20 168 252 3.7E-12 T 22-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 HRM2_RS15770 65e6d627c8a3f37dd1a40538f298bbc4 264 PANTHER PTHR12215 70 222 4.7E-20 T 22-04-2016 HRM2_RS15770 65e6d627c8a3f37dd1a40538f298bbc4 264 PANTHER PTHR12215:SF10 70 222 4.7E-20 T 22-04-2016 HRM2_RS21785 8859eae37e3e6f335062a4e7b6e6ef3c 228 SUPERFAMILY SSF48008 77 206 2.62E-20 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS21785 8859eae37e3e6f335062a4e7b6e6ef3c 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 71 2.3E-17 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS21785 8859eae37e3e6f335062a4e7b6e6ef3c 228 Gene3D G3DSA:1.10.10.10 9 72 4.3E-18 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS21785 8859eae37e3e6f335062a4e7b6e6ef3c 228 SMART SM00345 13 71 2.7E-14 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS21785 8859eae37e3e6f335062a4e7b6e6ef3c 228 SUPERFAMILY SSF46785 11 94 1.85E-16 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS21785 8859eae37e3e6f335062a4e7b6e6ef3c 228 Pfam PF07729 FCD domain 81 195 4.3E-19 T 22-04-2016 IPR011711 GntR, C-terminal HRM2_RS21785 8859eae37e3e6f335062a4e7b6e6ef3c 228 Gene3D G3DSA:1.20.120.530 75 209 4.0E-24 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS21785 8859eae37e3e6f335062a4e7b6e6ef3c 228 PANTHER PTHR11751 13 97 3.5E-20 T 22-04-2016 HRM2_RS21785 8859eae37e3e6f335062a4e7b6e6ef3c 228 SMART SM00895 81 200 1.0E-15 T 22-04-2016 IPR011711 GntR, C-terminal HRM2_RS07870 69a7dad3dc92db8c03168774ea80e2b6 385 PANTHER PTHR30158 32 378 1.3E-129 T 22-04-2016 HRM2_RS07870 69a7dad3dc92db8c03168774ea80e2b6 385 Gene3D G3DSA:2.40.50.100 179 213 2.6E-25 T 22-04-2016 HRM2_RS07870 69a7dad3dc92db8c03168774ea80e2b6 385 Gene3D G3DSA:2.40.50.100 71 104 2.6E-25 T 22-04-2016 HRM2_RS07870 69a7dad3dc92db8c03168774ea80e2b6 385 PANTHER PTHR30158:SF3 32 378 1.3E-129 T 22-04-2016 HRM2_RS07870 69a7dad3dc92db8c03168774ea80e2b6 385 SUPERFAMILY SSF111369 59 300 6.93E-76 T 22-04-2016 HRM2_RS07870 69a7dad3dc92db8c03168774ea80e2b6 385 Pfam PF00529 HlyD membrane-fusion protein of T1SS 162 363 3.6E-6 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 HRM2_RS07870 69a7dad3dc92db8c03168774ea80e2b6 385 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 46 377 2.2E-87 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 HRM2_RS07870 69a7dad3dc92db8c03168774ea80e2b6 385 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 70 295 8.9E-14 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain HRM2_RS25235 f63839b15731f540699664d1e2cfdce1 378 Pfam PF01590 GAF domain 27 154 1.1E-11 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS25235 f63839b15731f540699664d1e2cfdce1 378 SMART SM00065 25 167 5.6E-13 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS25235 f63839b15731f540699664d1e2cfdce1 378 SUPERFAMILY SSF55073 189 372 1.16E-42 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS25235 f63839b15731f540699664d1e2cfdce1 378 SUPERFAMILY SSF55781 27 167 2.4E-28 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS25235 f63839b15731f540699664d1e2cfdce1 378 PANTHER PTHR11920 145 377 1.1E-50 T 22-04-2016 HRM2_RS25235 f63839b15731f540699664d1e2cfdce1 378 SMART SM00044 168 357 4.5E-32 T 22-04-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 HRM2_RS25235 f63839b15731f540699664d1e2cfdce1 378 Gene3D G3DSA:3.30.450.40 25 169 9.1E-14 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS25235 f63839b15731f540699664d1e2cfdce1 378 Gene3D G3DSA:3.30.70.1230 189 378 4.0E-49 T 22-04-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 HRM2_RS25235 f63839b15731f540699664d1e2cfdce1 378 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 198 375 6.1E-38 T 22-04-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 HRM2_RS02160 289e3e5bacaa5bcc6ff6e2872f444f05 205 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 90 101 - T 22-04-2016 IPR018215 ClpP, Ser active site HRM2_RS02160 289e3e5bacaa5bcc6ff6e2872f444f05 205 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 44.893 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HRM2_RS02160 289e3e5bacaa5bcc6ff6e2872f444f05 205 SUPERFAMILY SSF52096 11 197 1.8E-74 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS02160 289e3e5bacaa5bcc6ff6e2872f444f05 205 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 22-04-2016 IPR033135 ClpP, histidine active site HRM2_RS02160 289e3e5bacaa5bcc6ff6e2872f444f05 205 Pfam PF00574 Clp protease 13 192 2.4E-88 T 22-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA HRM2_RS02160 289e3e5bacaa5bcc6ff6e2872f444f05 205 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 4.5E-54 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HRM2_RS02160 289e3e5bacaa5bcc6ff6e2872f444f05 205 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 4.5E-54 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HRM2_RS02160 289e3e5bacaa5bcc6ff6e2872f444f05 205 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 4.5E-54 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HRM2_RS02160 289e3e5bacaa5bcc6ff6e2872f444f05 205 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 4.5E-54 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HRM2_RS02160 289e3e5bacaa5bcc6ff6e2872f444f05 205 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 4.5E-54 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HRM2_RS02160 289e3e5bacaa5bcc6ff6e2872f444f05 205 Gene3D G3DSA:3.90.226.10 4 191 2.1E-89 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS02160 289e3e5bacaa5bcc6ff6e2872f444f05 205 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 3 191 1.3E-104 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HRM2_RS02160 289e3e5bacaa5bcc6ff6e2872f444f05 205 PANTHER PTHR10381 2 195 2.2E-136 T 22-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA HRM2_RS10365 8231d32806014407cc6418aeb9358070 698 PANTHER PTHR33362 6 688 2.2E-214 T 22-04-2016 HRM2_RS10365 8231d32806014407cc6418aeb9358070 698 Pfam PF11874 Domain of unknown function (DUF3394) 602 650 7.5E-14 T 22-04-2016 IPR021814 Protein of unknown function DUF3394 HRM2_RS10365 8231d32806014407cc6418aeb9358070 698 PANTHER PTHR33362:SF1 6 688 2.2E-214 T 22-04-2016 HRM2_RS10365 8231d32806014407cc6418aeb9358070 698 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 143 595 3.5E-75 T 22-04-2016 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit HRM2_RS10365 8231d32806014407cc6418aeb9358070 698 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 41 655 2.3E-191 T 22-04-2016 IPR011853 TRAP transporter, 4TM/12TM fusion protein HRM2_RS11085 b40687cacae9a7ae743c648ac4935be3 169 Gene3D G3DSA:3.40.50.1450 4 159 5.9E-45 T 22-04-2016 IPR023430 Peptidase HybD-like domain HRM2_RS11085 b40687cacae9a7ae743c648ac4935be3 169 PANTHER PTHR30302:SF1 1 165 1.3E-45 T 22-04-2016 HRM2_RS11085 b40687cacae9a7ae743c648ac4935be3 169 PRINTS PR00446 Hydrogen uptake protein signature 17 28 3.2E-20 T 22-04-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 HRM2_RS11085 b40687cacae9a7ae743c648ac4935be3 169 PRINTS PR00446 Hydrogen uptake protein signature 37 54 3.2E-20 T 22-04-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 HRM2_RS11085 b40687cacae9a7ae743c648ac4935be3 169 PRINTS PR00446 Hydrogen uptake protein signature 69 85 3.2E-20 T 22-04-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 HRM2_RS11085 b40687cacae9a7ae743c648ac4935be3 169 PRINTS PR00446 Hydrogen uptake protein signature 58 68 3.2E-20 T 22-04-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 HRM2_RS11085 b40687cacae9a7ae743c648ac4935be3 169 PRINTS PR00446 Hydrogen uptake protein signature 5 17 3.2E-20 T 22-04-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 HRM2_RS11085 b40687cacae9a7ae743c648ac4935be3 169 TIGRFAM TIGR00140 hupD: hydrogenase expression/formation protein 5 153 1.0E-46 T 22-04-2016 IPR004419 Peptidase A31, hydrogenase expression/formation protein GO:0016485|GO:0046872 HRM2_RS11085 b40687cacae9a7ae743c648ac4935be3 169 SUPERFAMILY SSF53163 4 158 4.97E-40 T 22-04-2016 IPR023430 Peptidase HybD-like domain HRM2_RS11085 b40687cacae9a7ae743c648ac4935be3 169 PANTHER PTHR30302 1 165 1.3E-45 T 22-04-2016 HRM2_RS11085 b40687cacae9a7ae743c648ac4935be3 169 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 6 150 9.7E-40 T 22-04-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 HRM2_RS11085 b40687cacae9a7ae743c648ac4935be3 169 Pfam PF01750 Hydrogenase maturation protease 22 149 3.7E-30 T 22-04-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 HRM2_RS17950 cfd1c68c4e9955ca1e25102ebb5c30fa 140 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 140 30.38 T 22-04-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17950 cfd1c68c4e9955ca1e25102ebb5c30fa 140 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 140 7.4E-65 T 22-04-2016 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 HRM2_RS17950 cfd1c68c4e9955ca1e25102ebb5c30fa 140 PANTHER PTHR11661 1 140 1.0E-69 T 22-04-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17950 cfd1c68c4e9955ca1e25102ebb5c30fa 140 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 66 4.7E-30 T 22-04-2016 IPR020784 Ribosomal protein L11, N-terminal HRM2_RS17950 cfd1c68c4e9955ca1e25102ebb5c30fa 140 SMART SM00649 9 140 2.2E-84 T 22-04-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17950 cfd1c68c4e9955ca1e25102ebb5c30fa 140 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 139 9.2E-25 T 22-04-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 HRM2_RS17950 cfd1c68c4e9955ca1e25102ebb5c30fa 140 Gene3D G3DSA:3.30.1550.10 2 71 1.3E-38 T 22-04-2016 IPR020784 Ribosomal protein L11, N-terminal HRM2_RS17950 cfd1c68c4e9955ca1e25102ebb5c30fa 140 SUPERFAMILY SSF46906 67 140 6.28E-27 T 22-04-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 HRM2_RS17950 cfd1c68c4e9955ca1e25102ebb5c30fa 140 Gene3D G3DSA:1.10.10.250 72 140 1.3E-31 T 22-04-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 HRM2_RS17950 cfd1c68c4e9955ca1e25102ebb5c30fa 140 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 73 3.0E-12 T 22-04-2016 HRM2_RS17950 cfd1c68c4e9955ca1e25102ebb5c30fa 140 SUPERFAMILY SSF54747 3 72 5.1E-30 T 22-04-2016 IPR020784 Ribosomal protein L11, N-terminal HRM2_RS07645 52cc1b2c20da879efce000d8b3edcdbb 219 Gene3D G3DSA:3.20.20.70 4 209 2.2E-64 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS07645 52cc1b2c20da879efce000d8b3edcdbb 219 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 7 209 25.402 T 22-04-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 HRM2_RS07645 52cc1b2c20da879efce000d8b3edcdbb 219 SUPERFAMILY SSF51391 6 208 1.83E-59 T 22-04-2016 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 HRM2_RS07645 52cc1b2c20da879efce000d8b3edcdbb 219 PANTHER PTHR20857:SF15 1 218 5.3E-59 T 22-04-2016 HRM2_RS07645 52cc1b2c20da879efce000d8b3edcdbb 219 PANTHER PTHR20857 1 218 5.3E-59 T 22-04-2016 HRM2_RS07645 52cc1b2c20da879efce000d8b3edcdbb 219 Pfam PF02581 Thiamine monophosphate synthase/TENI 10 191 2.8E-55 T 22-04-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 HRM2_RS07645 52cc1b2c20da879efce000d8b3edcdbb 219 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 9 203 8.3E-59 T 22-04-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 HRM2_RS13330 c63a431f60ef8870919c99dca90cb987 304 Pfam PF08279 HTH domain 7 48 5.2E-10 T 22-04-2016 IPR013196 Helix-turn-helix, type 11 HRM2_RS13330 c63a431f60ef8870919c99dca90cb987 304 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 1 300 29.218 T 22-04-2016 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 HRM2_RS13330 c63a431f60ef8870919c99dca90cb987 304 Gene3D G3DSA:2.30.30.100 253 296 1.2E-7 T 22-04-2016 HRM2_RS13330 c63a431f60ef8870919c99dca90cb987 304 Pfam PF02237 Biotin protein ligase C terminal domain 253 298 4.5E-6 T 22-04-2016 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15 HRM2_RS13330 c63a431f60ef8870919c99dca90cb987 304 SUPERFAMILY SSF46785 4 48 1.45E-7 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS13330 c63a431f60ef8870919c99dca90cb987 304 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 68 298 1.2E-56 T 22-04-2016 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 HRM2_RS13330 c63a431f60ef8870919c99dca90cb987 304 PANTHER PTHR12835 1 296 3.9E-75 T 22-04-2016 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 HRM2_RS13330 c63a431f60ef8870919c99dca90cb987 304 Gene3D G3DSA:1.10.10.10 6 52 4.0E-16 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS13330 c63a431f60ef8870919c99dca90cb987 304 SUPERFAMILY SSF50037 255 300 1.19E-6 T 22-04-2016 IPR008988 Transcriptional repressor, C-terminal HRM2_RS13330 c63a431f60ef8870919c99dca90cb987 304 Gene3D G3DSA:3.30.930.10 64 249 1.2E-54 T 22-04-2016 HRM2_RS13330 c63a431f60ef8870919c99dca90cb987 304 Pfam PF03099 Biotin/lipoate A/B protein ligase family 73 195 1.3E-14 T 22-04-2016 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 HRM2_RS13330 c63a431f60ef8870919c99dca90cb987 304 SUPERFAMILY SSF55681 67 245 2.65E-50 T 22-04-2016 HRM2_RS18980 f343ab8e8c95874f5fb1883026dcb2a5 389 Gene3D G3DSA:3.50.50.60 320 378 2.1E-55 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS18980 f343ab8e8c95874f5fb1883026dcb2a5 389 Gene3D G3DSA:3.50.50.60 147 225 2.1E-55 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS18980 f343ab8e8c95874f5fb1883026dcb2a5 389 Gene3D G3DSA:3.50.50.60 2 84 2.1E-55 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS18980 f343ab8e8c95874f5fb1883026dcb2a5 389 Pfam PF01266 FAD dependent oxidoreductase 6 359 1.1E-55 T 22-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 HRM2_RS18980 f343ab8e8c95874f5fb1883026dcb2a5 389 PANTHER PTHR13847 4 385 2.4E-89 T 22-04-2016 HRM2_RS18980 f343ab8e8c95874f5fb1883026dcb2a5 389 Gene3D G3DSA:3.30.9.10 226 317 1.1E-14 T 22-04-2016 HRM2_RS18980 f343ab8e8c95874f5fb1883026dcb2a5 389 Gene3D G3DSA:3.30.9.10 106 146 1.1E-14 T 22-04-2016 HRM2_RS18980 f343ab8e8c95874f5fb1883026dcb2a5 389 PANTHER PTHR13847:SF44 4 385 2.4E-89 T 22-04-2016 HRM2_RS18980 f343ab8e8c95874f5fb1883026dcb2a5 389 SUPERFAMILY SSF51905 4 226 5.7E-49 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS18980 f343ab8e8c95874f5fb1883026dcb2a5 389 SUPERFAMILY SSF51905 320 378 5.7E-49 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS23315 62b9644f3fff273d42228d56e61b3fa8 807 Gene3D G3DSA:2.40.40.20 604 801 4.5E-50 T 22-04-2016 HRM2_RS23315 62b9644f3fff273d42228d56e61b3fa8 807 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 714 741 - T 22-04-2016 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 HRM2_RS23315 62b9644f3fff273d42228d56e61b3fa8 807 Pfam PF00384 Molybdopterin oxidoreductase 2 374 2.8E-24 T 22-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 HRM2_RS23315 62b9644f3fff273d42228d56e61b3fa8 807 Gene3D G3DSA:3.40.50.740 320 463 1.7E-49 T 22-04-2016 HRM2_RS23315 62b9644f3fff273d42228d56e61b3fa8 807 TIGRFAM TIGR01553 formate-DH-alph: formate dehydrogenase-N alpha subunit 1 801 0.0 T 22-04-2016 IPR006443 Formate dehydrogenase-N, alpha subunit GO:0008863|GO:0009055|GO:0043546|GO:0045333|GO:0047111 HRM2_RS23315 62b9644f3fff273d42228d56e61b3fa8 807 Gene3D G3DSA:3.40.228.10 1 107 9.5E-73 T 22-04-2016 HRM2_RS23315 62b9644f3fff273d42228d56e61b3fa8 807 Gene3D G3DSA:3.40.228.10 151 258 9.5E-73 T 22-04-2016 HRM2_RS23315 62b9644f3fff273d42228d56e61b3fa8 807 PANTHER PTHR11615:SF126 664 801 1.5E-198 T 22-04-2016 HRM2_RS23315 62b9644f3fff273d42228d56e61b3fa8 807 PANTHER PTHR11615:SF126 209 278 1.5E-198 T 22-04-2016 HRM2_RS23315 62b9644f3fff273d42228d56e61b3fa8 807 PANTHER PTHR11615:SF126 1 181 1.5E-198 T 22-04-2016 HRM2_RS23315 62b9644f3fff273d42228d56e61b3fa8 807 PANTHER PTHR11615:SF126 320 478 1.5E-198 T 22-04-2016 HRM2_RS23315 62b9644f3fff273d42228d56e61b3fa8 807 PANTHER PTHR11615:SF126 576 645 1.5E-198 T 22-04-2016 HRM2_RS23315 62b9644f3fff273d42228d56e61b3fa8 807 SUPERFAMILY SSF50692 631 801 2.94E-46 T 22-04-2016 IPR009010 Aspartate decarboxylase-like domain HRM2_RS23315 62b9644f3fff273d42228d56e61b3fa8 807 Pfam PF01568 Molydopterin dinucleotide binding domain 678 795 7.3E-19 T 22-04-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 HRM2_RS23315 62b9644f3fff273d42228d56e61b3fa8 807 SUPERFAMILY SSF53706 1 637 1.15E-223 T 22-04-2016 HRM2_RS23315 62b9644f3fff273d42228d56e61b3fa8 807 PANTHER PTHR11615 664 801 1.5E-198 T 22-04-2016 HRM2_RS23315 62b9644f3fff273d42228d56e61b3fa8 807 PANTHER PTHR11615 209 278 1.5E-198 T 22-04-2016 HRM2_RS23315 62b9644f3fff273d42228d56e61b3fa8 807 PANTHER PTHR11615 1 181 1.5E-198 T 22-04-2016 HRM2_RS23315 62b9644f3fff273d42228d56e61b3fa8 807 PANTHER PTHR11615 320 478 1.5E-198 T 22-04-2016 HRM2_RS23315 62b9644f3fff273d42228d56e61b3fa8 807 PANTHER PTHR11615 576 645 1.5E-198 T 22-04-2016 HRM2_RS13935 cc3a2b7dadf97b2816b67a4b4a07e14f 258 SUPERFAMILY SSF57863 85 243 1.23E-30 T 22-04-2016 HRM2_RS13935 cc3a2b7dadf97b2816b67a4b4a07e14f 258 TIGRFAM TIGR00613 reco: DNA repair protein RecO 6 253 1.1E-44 T 22-04-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 HRM2_RS13935 cc3a2b7dadf97b2816b67a4b4a07e14f 258 PANTHER PTHR33991 2 257 8.4E-43 T 22-04-2016 HRM2_RS13935 cc3a2b7dadf97b2816b67a4b4a07e14f 258 Hamap MF_00201 DNA repair protein RecO [recO]. 2 254 24.271 T 22-04-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 HRM2_RS13935 cc3a2b7dadf97b2816b67a4b4a07e14f 258 SUPERFAMILY SSF50249 4 69 1.88E-14 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS13935 cc3a2b7dadf97b2816b67a4b4a07e14f 258 Gene3D G3DSA:2.40.50.140 4 85 6.2E-16 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS13935 cc3a2b7dadf97b2816b67a4b4a07e14f 258 Pfam PF11967 Recombination protein O N terminal 1 80 8.1E-20 T 22-04-2016 IPR022572 DNA replication/recombination mediator RecO, N-terminal HRM2_RS13935 cc3a2b7dadf97b2816b67a4b4a07e14f 258 Pfam PF02565 Recombination protein O C terminal 90 248 5.2E-28 T 22-04-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 HRM2_RS19095 af9861c84c282e8f507d0cfe8bc5a42f 591 SMART SM00790 4 211 1.3E-77 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS19095 af9861c84c282e8f507d0cfe8bc5a42f 591 PANTHER PTHR30038 1 588 1.6E-173 T 22-04-2016 HRM2_RS19095 af9861c84c282e8f507d0cfe8bc5a42f 591 SUPERFAMILY SSF56228 1 212 2.88E-59 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS19095 af9861c84c282e8f507d0cfe8bc5a42f 591 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 225 588 2.3E-108 T 22-04-2016 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS19095 af9861c84c282e8f507d0cfe8bc5a42f 591 SUPERFAMILY SSF48310 218 588 1.28E-95 T 22-04-2016 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS19095 af9861c84c282e8f507d0cfe8bc5a42f 591 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 7 209 1.3E-63 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS19095 af9861c84c282e8f507d0cfe8bc5a42f 591 Gene3D G3DSA:3.60.9.10 1 212 9.8E-69 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS19095 af9861c84c282e8f507d0cfe8bc5a42f 591 Gene3D G3DSA:1.10.569.10 245 427 2.3E-56 T 22-04-2016 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 HRM2_RS19095 af9861c84c282e8f507d0cfe8bc5a42f 591 PANTHER PTHR30038:SF0 1 588 1.6E-173 T 22-04-2016 HRM2_RS25510 209f3375dc74564c6ce4f5a25a4aa16f 672 SUPERFAMILY SSF55785 297 404 2.04E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS25510 209f3375dc74564c6ce4f5a25a4aa16f 672 Pfam PF00512 His Kinase A (phospho-acceptor) domain 443 509 5.0E-13 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25510 209f3375dc74564c6ce4f5a25a4aa16f 672 Gene3D G3DSA:1.10.287.130 436 507 8.6E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25510 209f3375dc74564c6ce4f5a25a4aa16f 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 613 623 1.2E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25510 209f3375dc74564c6ce4f5a25a4aa16f 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 595 609 1.2E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25510 209f3375dc74564c6ce4f5a25a4aa16f 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 623 641 1.2E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25510 209f3375dc74564c6ce4f5a25a4aa16f 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 647 660 1.2E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25510 209f3375dc74564c6ce4f5a25a4aa16f 672 PANTHER PTHR24423 141 147 7.3E-65 T 22-04-2016 HRM2_RS25510 209f3375dc74564c6ce4f5a25a4aa16f 672 PANTHER PTHR24423 296 665 7.3E-65 T 22-04-2016 HRM2_RS25510 209f3375dc74564c6ce4f5a25a4aa16f 672 SUPERFAMILY SSF47384 434 508 3.34E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25510 209f3375dc74564c6ce4f5a25a4aa16f 672 Gene3D G3DSA:3.30.450.20 306 388 2.3E-6 T 22-04-2016 HRM2_RS25510 209f3375dc74564c6ce4f5a25a4aa16f 672 PANTHER PTHR24423:SF497 296 665 7.3E-65 T 22-04-2016 HRM2_RS25510 209f3375dc74564c6ce4f5a25a4aa16f 672 Gene3D G3DSA:3.30.565.10 511 663 1.9E-35 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25510 209f3375dc74564c6ce4f5a25a4aa16f 672 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 554 662 1.4E-15 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25510 209f3375dc74564c6ce4f5a25a4aa16f 672 PANTHER PTHR24423:SF497 141 147 7.3E-65 T 22-04-2016 HRM2_RS25510 209f3375dc74564c6ce4f5a25a4aa16f 672 SMART SM00387 553 663 6.8E-26 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25510 209f3375dc74564c6ce4f5a25a4aa16f 672 Gene3D G3DSA:3.30.450.40 15 163 8.4E-5 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS25510 209f3375dc74564c6ce4f5a25a4aa16f 672 SUPERFAMILY SSF55874 503 664 6.29E-33 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25510 209f3375dc74564c6ce4f5a25a4aa16f 672 SMART SM00388 443 511 4.8E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25510 209f3375dc74564c6ce4f5a25a4aa16f 672 SUPERFAMILY SSF55781 14 165 7.63E-6 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS25510 209f3375dc74564c6ce4f5a25a4aa16f 672 Pfam PF01590 GAF domain 29 163 4.5E-5 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS11255 33ebaef3c2e85e7130491f27815d0a47 131 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 2 128 8.2E-48 T 22-04-2016 IPR001602 Uncharacterised protein family UPF0047 HRM2_RS11255 33ebaef3c2e85e7130491f27815d0a47 131 Gene3D G3DSA:2.60.120.460 2 127 2.5E-48 T 22-04-2016 IPR001602 Uncharacterised protein family UPF0047 HRM2_RS11255 33ebaef3c2e85e7130491f27815d0a47 131 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 92 110 - T 22-04-2016 IPR001602 Uncharacterised protein family UPF0047 HRM2_RS11255 33ebaef3c2e85e7130491f27815d0a47 131 PIRSF PIRSF004681 1 130 2.7E-42 T 22-04-2016 IPR001602 Uncharacterised protein family UPF0047 HRM2_RS11255 33ebaef3c2e85e7130491f27815d0a47 131 PANTHER PTHR30615 3 131 1.5E-53 T 22-04-2016 HRM2_RS11255 33ebaef3c2e85e7130491f27815d0a47 131 Pfam PF01894 Uncharacterised protein family UPF0047 15 127 7.5E-42 T 22-04-2016 IPR001602 Uncharacterised protein family UPF0047 HRM2_RS11255 33ebaef3c2e85e7130491f27815d0a47 131 SUPERFAMILY SSF111038 3 128 1.07E-46 T 22-04-2016 IPR001602 Uncharacterised protein family UPF0047 HRM2_RS20970 01e5315f59bed485f9e54b0e981cf2d4 194 Pfam PF01464 Transglycosylase SLT domain 74 175 6.0E-30 T 22-04-2016 IPR008258 Transglycosylase SLT domain 1 HRM2_RS20970 01e5315f59bed485f9e54b0e981cf2d4 194 Gene3D G3DSA:1.10.530.10 27 194 2.0E-52 T 22-04-2016 HRM2_RS20970 01e5315f59bed485f9e54b0e981cf2d4 194 PANTHER PTHR21666 53 192 4.7E-41 T 22-04-2016 HRM2_RS20970 01e5315f59bed485f9e54b0e981cf2d4 194 SUPERFAMILY SSF53955 66 193 2.7E-46 T 22-04-2016 IPR023346 Lysozyme-like domain HRM2_RS20970 01e5315f59bed485f9e54b0e981cf2d4 194 Pfam PF13511 Domain of unknown function (DUF4124) 14 46 2.3E-6 T 22-04-2016 IPR025392 Domain of unknown function DUF4124 HRM2_RS22385 96be2535906bf3db301ae3f911e95554 850 SUPERFAMILY SSF51126 738 842 1.55E-5 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor HRM2_RS22385 96be2535906bf3db301ae3f911e95554 850 Gene3D G3DSA:2.160.20.10 38 161 4.5E-36 T 22-04-2016 IPR012334 Pectin lyase fold HRM2_RS22385 96be2535906bf3db301ae3f911e95554 850 Gene3D G3DSA:2.160.20.10 209 443 4.5E-36 T 22-04-2016 IPR012334 Pectin lyase fold HRM2_RS22385 96be2535906bf3db301ae3f911e95554 850 Gene3D G3DSA:2.160.20.10 485 832 1.2E-29 T 22-04-2016 IPR012334 Pectin lyase fold HRM2_RS22385 96be2535906bf3db301ae3f911e95554 850 SMART SM00710 141 167 6900.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat HRM2_RS22385 96be2535906bf3db301ae3f911e95554 850 SMART SM00710 774 800 1400.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat HRM2_RS22385 96be2535906bf3db301ae3f911e95554 850 SMART SM00710 801 829 10000.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat HRM2_RS22385 96be2535906bf3db301ae3f911e95554 850 SMART SM00710 695 720 5100.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat HRM2_RS22385 96be2535906bf3db301ae3f911e95554 850 SMART SM00710 326 350 3700.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat HRM2_RS22385 96be2535906bf3db301ae3f911e95554 850 SMART SM00710 216 241 620.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat HRM2_RS22385 96be2535906bf3db301ae3f911e95554 850 SMART SM00710 246 281 3100.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat HRM2_RS22385 96be2535906bf3db301ae3f911e95554 850 SMART SM00710 643 668 4800.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat HRM2_RS22385 96be2535906bf3db301ae3f911e95554 850 SMART SM00710 669 693 1500.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat HRM2_RS22385 96be2535906bf3db301ae3f911e95554 850 SMART SM00710 595 636 8400.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat HRM2_RS22385 96be2535906bf3db301ae3f911e95554 850 SMART SM00710 722 748 2500.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat HRM2_RS22385 96be2535906bf3db301ae3f911e95554 850 SUPERFAMILY SSF51126 485 749 1.44E-19 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor HRM2_RS22385 96be2535906bf3db301ae3f911e95554 850 SUPERFAMILY SSF51126 209 428 1.39E-33 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor HRM2_RS22385 96be2535906bf3db301ae3f911e95554 850 SUPERFAMILY SSF51126 15 161 1.39E-33 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor HRM2_RS07050 9bd8cd22c5ee9a36936d977281179da9 461 PANTHER PTHR11986 1 461 4.6E-150 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HRM2_RS07050 9bd8cd22c5ee9a36936d977281179da9 461 SUPERFAMILY SSF53383 75 459 8.44E-111 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS07050 9bd8cd22c5ee9a36936d977281179da9 461 PANTHER PTHR11986:SF75 1 461 4.6E-150 T 22-04-2016 HRM2_RS07050 9bd8cd22c5ee9a36936d977281179da9 461 Gene3D G3DSA:3.90.1150.10 347 459 3.0E-26 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS07050 9bd8cd22c5ee9a36936d977281179da9 461 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 276 313 - T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HRM2_RS07050 9bd8cd22c5ee9a36936d977281179da9 461 Gene3D G3DSA:3.40.640.10 111 346 1.3E-83 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS07050 9bd8cd22c5ee9a36936d977281179da9 461 Pfam PF00202 Aminotransferase class-III 81 456 1.3E-95 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HRM2_RS08755 1e196a1a5625d68552de592a02ce70d0 151 Pfam PF01592 NifU-like N terminal domain 42 131 3.2E-13 T 22-04-2016 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 HRM2_RS08755 1e196a1a5625d68552de592a02ce70d0 151 Gene3D G3DSA:3.90.1010.10 26 131 1.8E-16 T 22-04-2016 HRM2_RS08755 1e196a1a5625d68552de592a02ce70d0 151 SUPERFAMILY SSF82649 18 134 4.71E-21 T 22-04-2016 HRM2_RS22230 80ca0bf3631089e184a29132dadd9ced 263 SUPERFAMILY SSF56014 198 261 4.06E-23 T 22-04-2016 HRM2_RS22230 80ca0bf3631089e184a29132dadd9ced 263 SUPERFAMILY SSF56014 63 140 4.06E-23 T 22-04-2016 HRM2_RS22230 80ca0bf3631089e184a29132dadd9ced 263 Gene3D G3DSA:3.30.70.20 154 197 1.2E-15 T 22-04-2016 HRM2_RS22230 80ca0bf3631089e184a29132dadd9ced 263 Pfam PF12838 4Fe-4S dicluster domain 146 191 4.4E-11 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS22230 80ca0bf3631089e184a29132dadd9ced 263 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 63 262 2.7E-15 T 22-04-2016 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 HRM2_RS22230 80ca0bf3631089e184a29132dadd9ced 263 Pfam PF08369 Proto-chlorophyllide reductase 57 kD subunit 3 45 2.0E-14 T 22-04-2016 IPR013580 Proto-chlorophyllide/chlorophyllide reductase, C-terminal GO:0015979|GO:0015995|GO:0016491|GO:0055114 KEGG: 00860+1.3.7.7|MetaCyc: PWY-5531|MetaCyc: PWY-7159 HRM2_RS22230 80ca0bf3631089e184a29132dadd9ced 263 Gene3D G3DSA:3.30.413.10 199 261 6.8E-27 T 22-04-2016 HRM2_RS22230 80ca0bf3631089e184a29132dadd9ced 263 Gene3D G3DSA:3.30.413.10 63 128 6.8E-27 T 22-04-2016 HRM2_RS22230 80ca0bf3631089e184a29132dadd9ced 263 SUPERFAMILY SSF54862 116 193 6.42E-19 T 22-04-2016 HRM2_RS22230 80ca0bf3631089e184a29132dadd9ced 263 Gene3D G3DSA:3.30.70.20 129 153 7.3E-4 T 22-04-2016 HRM2_RS22230 80ca0bf3631089e184a29132dadd9ced 263 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 178 189 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 SUPERFAMILY SSF51905 989 1315 6.09E-23 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 SUPERFAMILY SSF54862 1147 1167 7.45E-18 T 22-04-2016 HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 SUPERFAMILY SSF54862 1303 1388 7.45E-18 T 22-04-2016 HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 993 1308 1.2E-8 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 572 820 1.9E-18 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 172 470 1.4E-35 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 Gene3D G3DSA:3.50.50.60 1270 1321 1.5E-30 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 Gene3D G3DSA:3.50.50.60 993 1128 1.5E-30 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 Gene3D G3DSA:3.40.50.720 173 401 1.7E-50 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 1338 1349 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 Gene3D G3DSA:1.10.1060.10 87 172 9.7E-23 T 22-04-2016 HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 Gene3D G3DSA:1.10.1060.10 653 673 3.1E-15 T 22-04-2016 HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 Gene3D G3DSA:1.10.1060.10 499 615 3.1E-15 T 22-04-2016 HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 Pfam PF00037 4Fe-4S binding domain 1362 1383 6.6E-5 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 Pfam PF00037 4Fe-4S binding domain 27 47 2.6E-6 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 SUPERFAMILY SSF46548 27 181 1.36E-20 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 PRINTS PR00419 Adrenodoxin reductase family signature 305 319 1.7E-16 T 22-04-2016 HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 PRINTS PR00419 Adrenodoxin reductase family signature 172 194 1.7E-16 T 22-04-2016 HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 PRINTS PR00419 Adrenodoxin reductase family signature 195 208 1.7E-16 T 22-04-2016 HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 552 563 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 Gene3D G3DSA:3.30.70.20 41 86 1.3E-6 T 22-04-2016 HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 Gene3D G3DSA:3.30.70.20 21 40 1.4E-18 T 22-04-2016 HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 Gene3D G3DSA:3.30.70.20 1335 1392 1.4E-18 T 22-04-2016 HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 33 44 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 PANTHER PTHR11938:SF99 66 696 2.7E-89 T 22-04-2016 HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 PANTHER PTHR11938 66 696 2.7E-89 T 22-04-2016 HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 SUPERFAMILY SSF46548 480 569 5.75E-9 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 SUPERFAMILY SSF51971 171 415 7.65E-55 T 22-04-2016 HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 Gene3D G3DSA:3.50.50.60 694 829 2.7E-11 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 1368 1379 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 SUPERFAMILY SSF51905 578 829 4.86E-11 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 80 157 2.1E-15 T 22-04-2016 IPR028261 Dihydroprymidine dehydrogenase domain II HRM2_RS15245 a268787ea3fe2c5b5bd79a9fd55ed369 1405 Gene3D G3DSA:3.50.50.60 402 469 3.4E-4 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS13045 4358e827e1db66dcfa9f014d53a2e587 328 Gene3D G3DSA:1.10.443.10 110 300 1.9E-28 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS13045 4358e827e1db66dcfa9f014d53a2e587 328 SUPERFAMILY SSF56349 90 300 1.53E-29 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HRM2_RS13045 4358e827e1db66dcfa9f014d53a2e587 328 PANTHER PTHR30349 136 327 8.4E-16 T 22-04-2016 HRM2_RS13045 4358e827e1db66dcfa9f014d53a2e587 328 Pfam PF00589 Phage integrase family 142 298 9.9E-20 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS00255 37a793f36d38bdedabed277eb95cf58a 243 Pfam PF01925 Sulfite exporter TauE/SafE 6 233 8.8E-19 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 HRM2_RS14775 3860cd780ea17519c64ce63cea0e19af 310 Pfam PF00535 Glycosyl transferase family 2 9 171 1.1E-27 T 22-04-2016 IPR001173 Glycosyltransferase 2-like HRM2_RS14775 3860cd780ea17519c64ce63cea0e19af 310 PANTHER PTHR10859 8 309 6.6E-143 T 22-04-2016 HRM2_RS14775 3860cd780ea17519c64ce63cea0e19af 310 Gene3D G3DSA:3.90.550.10 8 163 9.0E-23 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS14775 3860cd780ea17519c64ce63cea0e19af 310 SUPERFAMILY SSF53448 4 242 1.88E-34 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS14775 3860cd780ea17519c64ce63cea0e19af 310 PANTHER PTHR10859:SF81 8 309 6.6E-143 T 22-04-2016 HRM2_RS09290 62c8a32ae613b733d9cd7a323a0fb0ca 83 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 27 80 3.0E-16 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS09290 62c8a32ae613b733d9cd7a323a0fb0ca 83 SUPERFAMILY SSF46911 6 81 3.92E-29 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS09290 62c8a32ae613b733d9cd7a323a0fb0ca 83 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 10 81 21.675 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS09290 62c8a32ae613b733d9cd7a323a0fb0ca 83 PANTHER PTHR13479 9 81 2.4E-27 T 22-04-2016 HRM2_RS09290 62c8a32ae613b733d9cd7a323a0fb0ca 83 Pfam PF01084 Ribosomal protein S18 27 76 4.7E-25 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS09290 62c8a32ae613b733d9cd7a323a0fb0ca 83 PRINTS PR00974 Ribosomal protein S18 family signature 36 46 6.1E-19 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS09290 62c8a32ae613b733d9cd7a323a0fb0ca 83 PRINTS PR00974 Ribosomal protein S18 family signature 68 78 6.1E-19 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS09290 62c8a32ae613b733d9cd7a323a0fb0ca 83 PRINTS PR00974 Ribosomal protein S18 family signature 46 53 6.1E-19 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS09290 62c8a32ae613b733d9cd7a323a0fb0ca 83 PRINTS PR00974 Ribosomal protein S18 family signature 54 68 6.1E-19 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS09290 62c8a32ae613b733d9cd7a323a0fb0ca 83 TIGRFAM TIGR00165 S18: ribosomal protein bS18 12 80 1.2E-31 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS09290 62c8a32ae613b733d9cd7a323a0fb0ca 83 Gene3D G3DSA:4.10.640.10 16 81 1.2E-31 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS16255 db9c861391eb271e3f3ad0e010fc5c5d 66 PIRSF PIRSF002599 1 66 9.2E-24 T 22-04-2016 IPR012156 Cold shock, CspA GO:0003676 HRM2_RS16255 db9c861391eb271e3f3ad0e010fc5c5d 66 SMART SM00357 3 66 2.9E-29 T 22-04-2016 IPR011129 Cold shock protein GO:0003676 HRM2_RS16255 db9c861391eb271e3f3ad0e010fc5c5d 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 5.0E-29 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HRM2_RS16255 db9c861391eb271e3f3ad0e010fc5c5d 66 PRINTS PR00050 Cold shock protein signature 4 19 3.7E-18 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HRM2_RS16255 db9c861391eb271e3f3ad0e010fc5c5d 66 PRINTS PR00050 Cold shock protein signature 24 33 3.7E-18 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HRM2_RS16255 db9c861391eb271e3f3ad0e010fc5c5d 66 PRINTS PR00050 Cold shock protein signature 39 57 3.7E-18 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HRM2_RS16255 db9c861391eb271e3f3ad0e010fc5c5d 66 PANTHER PTHR11544 1 66 1.2E-34 T 22-04-2016 HRM2_RS16255 db9c861391eb271e3f3ad0e010fc5c5d 66 Gene3D G3DSA:2.40.50.140 1 66 2.8E-30 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS16255 db9c861391eb271e3f3ad0e010fc5c5d 66 SUPERFAMILY SSF50249 1 65 9.64E-24 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS16255 db9c861391eb271e3f3ad0e010fc5c5d 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 22-04-2016 IPR019844 Cold-shock conserved site HRM2_RS23860 ae95364cb35e11568c79123752dbf775 114 Pfam PF01022 Bacterial regulatory protein, arsR family 13 59 1.7E-16 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HRM2_RS23860 ae95364cb35e11568c79123752dbf775 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 8 23 6.5E-16 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HRM2_RS23860 ae95364cb35e11568c79123752dbf775 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 6.5E-16 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HRM2_RS23860 ae95364cb35e11568c79123752dbf775 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 27 38 6.5E-16 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HRM2_RS23860 ae95364cb35e11568c79123752dbf775 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 6.5E-16 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HRM2_RS23860 ae95364cb35e11568c79123752dbf775 114 PANTHER PTHR33154 6 96 4.9E-19 T 22-04-2016 HRM2_RS23860 ae95364cb35e11568c79123752dbf775 114 Gene3D G3DSA:1.10.10.10 3 92 7.7E-26 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS23860 ae95364cb35e11568c79123752dbf775 114 SMART SM00418 6 92 2.6E-21 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HRM2_RS23860 ae95364cb35e11568c79123752dbf775 114 SUPERFAMILY SSF46785 4 92 7.37E-24 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS13975 72b2cf00c8cd9b27afee20d2a8aece18 97 SUPERFAMILY SSF54909 1 96 6.71E-29 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel HRM2_RS13975 72b2cf00c8cd9b27afee20d2a8aece18 97 PANTHER PTHR33336 1 96 1.4E-25 T 22-04-2016 HRM2_RS13975 72b2cf00c8cd9b27afee20d2a8aece18 97 Gene3D G3DSA:3.30.70.900 4 95 7.6E-32 T 22-04-2016 HRM2_RS13975 72b2cf00c8cd9b27afee20d2a8aece18 97 Pfam PF03992 Antibiotic biosynthesis monooxygenase 4 78 6.2E-21 T 22-04-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain HRM2_RS05285 45056469fd504980e3222148a4ab4242 158 SUPERFAMILY SSF55021 6 39 1.9E-6 T 22-04-2016 HRM2_RS05285 45056469fd504980e3222148a4ab4242 158 SUPERFAMILY SSF55021 100 146 4.81E-7 T 22-04-2016 HRM2_RS05285 45056469fd504980e3222148a4ab4242 158 Gene3D G3DSA:3.30.70.260 7 41 2.0E-5 T 22-04-2016 HRM2_RS05285 45056469fd504980e3222148a4ab4242 158 Gene3D G3DSA:3.30.70.260 80 132 2.5E-5 T 22-04-2016 HRM2_RS05285 45056469fd504980e3222148a4ab4242 158 PANTHER PTHR40099:SF1 70 158 6.2E-15 T 22-04-2016 HRM2_RS05285 45056469fd504980e3222148a4ab4242 158 PANTHER PTHR40099:SF1 1 38 6.2E-15 T 22-04-2016 HRM2_RS05285 45056469fd504980e3222148a4ab4242 158 PANTHER PTHR40099 70 158 6.2E-15 T 22-04-2016 HRM2_RS05285 45056469fd504980e3222148a4ab4242 158 PANTHER PTHR40099 1 38 6.2E-15 T 22-04-2016 HRM2_RS08120 484ad21cbbc1fe66ab47077bdb826e91 333 SUPERFAMILY SSF54106 30 78 2.62E-7 T 22-04-2016 IPR018392 LysM domain HRM2_RS08120 484ad21cbbc1fe66ab47077bdb826e91 333 Pfam PF01476 LysM domain 32 78 9.0E-12 T 22-04-2016 IPR018392 LysM domain HRM2_RS08120 484ad21cbbc1fe66ab47077bdb826e91 333 PANTHER PTHR34700 17 320 1.7E-22 T 22-04-2016 HRM2_RS08120 484ad21cbbc1fe66ab47077bdb826e91 333 SMART SM00257 31 79 4.4E-5 T 22-04-2016 IPR018392 LysM domain HRM2_RS08120 484ad21cbbc1fe66ab47077bdb826e91 333 Gene3D G3DSA:3.10.350.10 31 78 2.1E-6 T 22-04-2016 IPR018392 LysM domain HRM2_RS02695 d2a1e1f52e9ad2ee4c0902af537492e5 338 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 2 327 6.9E-82 T 22-04-2016 IPR002729 CRISPR-associated protein Cas1 HRM2_RS02695 d2a1e1f52e9ad2ee4c0902af537492e5 338 PANTHER PTHR34353 1 335 6.5E-66 T 22-04-2016 HRM2_RS02695 d2a1e1f52e9ad2ee4c0902af537492e5 338 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 2 338 21.62 T 22-04-2016 IPR002729 CRISPR-associated protein Cas1 HRM2_RS02695 d2a1e1f52e9ad2ee4c0902af537492e5 338 Pfam PF01867 CRISPR associated protein Cas1 3 290 1.2E-75 T 22-04-2016 IPR002729 CRISPR-associated protein Cas1 HRM2_RS19665 b526c3443554468d87dee6eecdc4b956 338 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 65 76 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS19665 b526c3443554468d87dee6eecdc4b956 338 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 29 40 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS19665 b526c3443554468d87dee6eecdc4b956 338 PANTHER PTHR23026 101 333 4.6E-44 T 22-04-2016 HRM2_RS19665 b526c3443554468d87dee6eecdc4b956 338 SUPERFAMILY SSF55469 126 187 3.53E-49 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 HRM2_RS19665 b526c3443554468d87dee6eecdc4b956 338 SUPERFAMILY SSF55469 235 334 3.53E-49 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 HRM2_RS19665 b526c3443554468d87dee6eecdc4b956 338 Pfam PF12838 4Fe-4S dicluster domain 28 77 1.5E-6 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS19665 b526c3443554468d87dee6eecdc4b956 338 Gene3D G3DSA:3.40.109.10 126 333 1.2E-51 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 HRM2_RS19665 b526c3443554468d87dee6eecdc4b956 338 SUPERFAMILY SSF54862 21 92 1.19E-15 T 22-04-2016 HRM2_RS19665 b526c3443554468d87dee6eecdc4b956 338 Gene3D G3DSA:3.30.70.20 8 87 9.7E-14 T 22-04-2016 HRM2_RS19665 b526c3443554468d87dee6eecdc4b956 338 Pfam PF00881 Nitroreductase family 131 317 2.8E-37 T 22-04-2016 IPR029479 Nitroreductase HRM2_RS14760 64fda211024dcbe89673ffab20f82542 476 PANTHER PTHR13285 1 431 2.9E-90 T 22-04-2016 HRM2_RS14760 64fda211024dcbe89673ffab20f82542 476 PIRSF PIRSF016636 1 476 2.3E-140 T 22-04-2016 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB HRM2_RS14760 64fda211024dcbe89673ffab20f82542 476 PIRSF PIRSF500217 1 476 1.8E-145 T 22-04-2016 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 KEGG: 00061+2.3.1.-|KEGG: 00253+2.3.1.-|KEGG: 00261+2.3.1.-|KEGG: 00310+2.3.1.-|KEGG: 00330+2.3.1.-|KEGG: 00332+2.3.1.-|KEGG: 00340+2.3.1.-|KEGG: 00350+2.3.1.-|KEGG: 00564+2.3.1.-|KEGG: 00565+2.3.1.-|KEGG: 00604+2.3.1.-|KEGG: 00623+2.3.1.-|KEGG: 00626+2.3.1.-|KEGG: 00627+2.3.1.-|KEGG: 00642+2.3.1.-|KEGG: 00650+2.3.1.-|KEGG: 00680+2.3.1.-|KEGG: 00903+2.3.1.-|KEGG: 00904+2.3.1.-|KEGG: 00906+2.3.1.-|KEGG: 00940+2.3.1.-|KEGG: 00942+2.3.1.-|KEGG: 00950+2.3.1.-|KEGG: 00960+2.3.1.-|KEGG: 00965+2.3.1.-|UniPathway: UPA00286 HRM2_RS14760 64fda211024dcbe89673ffab20f82542 476 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 147 371 3.7E-24 T 22-04-2016 IPR004299 Membrane bound O-acyl transferase, MBOAT HRM2_RS14760 64fda211024dcbe89673ffab20f82542 476 PANTHER PTHR13285:SF23 1 431 2.9E-90 T 22-04-2016 HRM2_RS14695 70419b587de5b89961b7cb1939b4af17 333 PANTHER PTHR10366:SF77 3 333 2.8E-182 T 22-04-2016 HRM2_RS14695 70419b587de5b89961b7cb1939b4af17 333 Gene3D G3DSA:3.90.25.10 185 329 4.8E-31 T 22-04-2016 HRM2_RS14695 70419b587de5b89961b7cb1939b4af17 333 PRINTS PR01713 Nucleotide sugar epimerase signature 252 267 3.0E-28 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 HRM2_RS14695 70419b587de5b89961b7cb1939b4af17 333 PRINTS PR01713 Nucleotide sugar epimerase signature 291 308 3.0E-28 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 HRM2_RS14695 70419b587de5b89961b7cb1939b4af17 333 PRINTS PR01713 Nucleotide sugar epimerase signature 217 232 3.0E-28 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 HRM2_RS14695 70419b587de5b89961b7cb1939b4af17 333 PRINTS PR01713 Nucleotide sugar epimerase signature 30 46 3.0E-28 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 HRM2_RS14695 70419b587de5b89961b7cb1939b4af17 333 PANTHER PTHR10366 3 333 2.8E-182 T 22-04-2016 HRM2_RS14695 70419b587de5b89961b7cb1939b4af17 333 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 237 2.8E-56 T 22-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 HRM2_RS14695 70419b587de5b89961b7cb1939b4af17 333 Gene3D G3DSA:3.40.50.720 2 184 3.0E-50 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS14695 70419b587de5b89961b7cb1939b4af17 333 SUPERFAMILY SSF51735 2 330 3.1E-91 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS13665 ef7d995476e626ce9e34de3ddb30405c 297 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 1 297 31.737 T 22-04-2016 IPR023009 Tyrosine recombinase XerC/XerD HRM2_RS13665 ef7d995476e626ce9e34de3ddb30405c 297 Gene3D G3DSA:1.10.443.10 118 290 1.9E-54 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS13665 ef7d995476e626ce9e34de3ddb30405c 297 Pfam PF00589 Phage integrase family 118 283 3.4E-44 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS13665 ef7d995476e626ce9e34de3ddb30405c 297 Gene3D G3DSA:1.10.150.130 3 106 2.0E-22 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal HRM2_RS13665 ef7d995476e626ce9e34de3ddb30405c 297 SUPERFAMILY SSF56349 4 290 3.24E-60 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HRM2_RS13665 ef7d995476e626ce9e34de3ddb30405c 297 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 4 93 1.4E-16 T 22-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 HRM2_RS13665 ef7d995476e626ce9e34de3ddb30405c 297 PANTHER PTHR30349:SF17 1 296 8.6E-90 T 22-04-2016 HRM2_RS13665 ef7d995476e626ce9e34de3ddb30405c 297 PANTHER PTHR30349 1 296 8.6E-90 T 22-04-2016 HRM2_RS03430 719669ccf732529e36941f25a42e2bdf 807 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 392 403 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS03430 719669ccf732529e36941f25a42e2bdf 807 Pfam PF13534 4Fe-4S dicluster domain 342 406 3.2E-11 T 22-04-2016 HRM2_RS03430 719669ccf732529e36941f25a42e2bdf 807 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 33 124 6.2E-17 T 22-04-2016 IPR028261 Dihydroprymidine dehydrogenase domain II HRM2_RS03430 719669ccf732529e36941f25a42e2bdf 807 SUPERFAMILY SSF51971 95 209 1.12E-6 T 22-04-2016 HRM2_RS03430 719669ccf732529e36941f25a42e2bdf 807 Gene3D G3DSA:3.40.50.720 142 210 1.7E-6 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS03430 719669ccf732529e36941f25a42e2bdf 807 PANTHER PTHR32479 341 663 2.6E-23 T 22-04-2016 HRM2_RS03430 719669ccf732529e36941f25a42e2bdf 807 SUPERFAMILY SSF54862 335 429 7.11E-12 T 22-04-2016 HRM2_RS03430 719669ccf732529e36941f25a42e2bdf 807 Pfam PF02754 Cysteine-rich domain 582 664 5.4E-6 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS03430 719669ccf732529e36941f25a42e2bdf 807 Pfam PF02754 Cysteine-rich domain 460 540 0.0034 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS03430 719669ccf732529e36941f25a42e2bdf 807 SUPERFAMILY SSF46548 13 124 9.42E-15 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS03430 719669ccf732529e36941f25a42e2bdf 807 Gene3D G3DSA:1.10.1060.10 328 428 4.1E-15 T 22-04-2016 HRM2_RS03430 719669ccf732529e36941f25a42e2bdf 807 Gene3D G3DSA:1.10.1060.10 32 141 4.2E-21 T 22-04-2016 HRM2_RS03430 719669ccf732529e36941f25a42e2bdf 807 PANTHER PTHR32479:SF12 341 663 2.6E-23 T 22-04-2016 HRM2_RS12440 490485dedbb306ee7b2af344dfc65126 147 PANTHER PTHR30154 1 141 2.2E-21 T 22-04-2016 HRM2_RS12440 490485dedbb306ee7b2af344dfc65126 147 Gene3D G3DSA:3.30.70.920 64 139 1.7E-13 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain HRM2_RS12440 490485dedbb306ee7b2af344dfc65126 147 SMART SM00344 3 107 3.9E-18 T 22-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 HRM2_RS12440 490485dedbb306ee7b2af344dfc65126 147 SUPERFAMILY SSF46785 3 50 2.95E-7 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS12440 490485dedbb306ee7b2af344dfc65126 147 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 48 1.9E-8 T 22-04-2016 HRM2_RS12440 490485dedbb306ee7b2af344dfc65126 147 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 2.6E-5 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 HRM2_RS12440 490485dedbb306ee7b2af344dfc65126 147 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 2.6E-5 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 HRM2_RS12440 490485dedbb306ee7b2af344dfc65126 147 Pfam PF01037 Lrp/AsnC ligand binding domain 68 137 1.3E-9 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain HRM2_RS12440 490485dedbb306ee7b2af344dfc65126 147 Gene3D G3DSA:1.10.10.10 1 48 5.6E-10 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS12440 490485dedbb306ee7b2af344dfc65126 147 ProSitePatterns PS00519 AsnC-type HTH domain signature. 20 46 - T 22-04-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site HRM2_RS12440 490485dedbb306ee7b2af344dfc65126 147 SUPERFAMILY SSF54909 64 139 6.44E-11 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel HRM2_RS21430 d8ecd843da001812b7d198e2495a499c 256 SUPERFAMILY SSF53067 4 247 7.57E-43 T 22-04-2016 HRM2_RS21430 d8ecd843da001812b7d198e2495a499c 256 Gene3D G3DSA:3.30.420.40 92 230 2.8E-47 T 22-04-2016 HRM2_RS21430 d8ecd843da001812b7d198e2495a499c 256 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 5 247 4.0E-61 T 22-04-2016 IPR008275 CoA enzyme activase HRM2_RS21430 d8ecd843da001812b7d198e2495a499c 256 Gene3D G3DSA:3.30.420.40 1 43 3.7E-4 T 22-04-2016 HRM2_RS21430 d8ecd843da001812b7d198e2495a499c 256 PANTHER PTHR32329 3 256 3.3E-94 T 22-04-2016 HRM2_RS21430 d8ecd843da001812b7d198e2495a499c 256 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 6 247 5.1E-49 T 22-04-2016 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type HRM2_RS10745 92c5bd6193fbd9a43b83f56afcb3c567 460 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 14 459 64.336 T 22-04-2016 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 HRM2_RS10745 92c5bd6193fbd9a43b83f56afcb3c567 460 Pfam PF00919 Uncharacterized protein family UPF0004 17 114 1.2E-24 T 22-04-2016 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 HRM2_RS10745 92c5bd6193fbd9a43b83f56afcb3c567 460 Pfam PF04055 Radical SAM superfamily 163 334 2.4E-31 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS10745 92c5bd6193fbd9a43b83f56afcb3c567 460 Gene3D G3DSA:3.80.30.20 158 388 3.0E-80 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe HRM2_RS10745 92c5bd6193fbd9a43b83f56afcb3c567 460 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 163 183 - T 22-04-2016 IPR020612 Methylthiotransferase, conserved site GO:0051539 HRM2_RS10745 92c5bd6193fbd9a43b83f56afcb3c567 460 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 17 455 3.2E-146 T 22-04-2016 HRM2_RS10745 92c5bd6193fbd9a43b83f56afcb3c567 460 PANTHER PTHR11918:SF43 17 454 2.7E-163 T 22-04-2016 HRM2_RS10745 92c5bd6193fbd9a43b83f56afcb3c567 460 SMART SM00729 159 376 5.9E-58 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS10745 92c5bd6193fbd9a43b83f56afcb3c567 460 SUPERFAMILY SSF102114 154 381 1.12E-60 T 22-04-2016 HRM2_RS10745 92c5bd6193fbd9a43b83f56afcb3c567 460 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 17 456 7.1E-141 T 22-04-2016 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 HRM2_RS10745 92c5bd6193fbd9a43b83f56afcb3c567 460 PANTHER PTHR11918 17 454 2.7E-163 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein HRM2_RS10840 09bb0499f030b5cb94ffb2b445414134 487 SMART SM00881 14 109 4.9E-19 T 22-04-2016 IPR003781 CoA-binding GO:0048037 HRM2_RS10840 09bb0499f030b5cb94ffb2b445414134 487 SUPERFAMILY SSF51735 13 148 3.78E-31 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS10840 09bb0499f030b5cb94ffb2b445414134 487 Gene3D G3DSA:3.40.50.720 11 140 6.8E-33 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS10840 09bb0499f030b5cb94ffb2b445414134 487 SUPERFAMILY SSF52210 138 298 6.93E-40 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS10840 09bb0499f030b5cb94ffb2b445414134 487 PANTHER PTHR11117 44 486 7.5E-111 T 22-04-2016 HRM2_RS10840 09bb0499f030b5cb94ffb2b445414134 487 SUPERFAMILY SSF52210 305 481 1.7E-26 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS10840 09bb0499f030b5cb94ffb2b445414134 487 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 161 296 1.7E-45 T 22-04-2016 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain HRM2_RS10840 09bb0499f030b5cb94ffb2b445414134 487 Pfam PF13380 CoA binding domain 19 144 2.9E-18 T 22-04-2016 IPR003781 CoA-binding GO:0048037 HRM2_RS10840 09bb0499f030b5cb94ffb2b445414134 487 PANTHER PTHR11117:SF8 44 486 7.5E-111 T 22-04-2016 HRM2_RS10840 09bb0499f030b5cb94ffb2b445414134 487 Gene3D G3DSA:3.40.50.261 141 293 9.3E-30 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS05685 cc7332a3b602298c5514751350654b2d 303 PANTHER PTHR18895:SF3 93 299 4.2E-67 T 22-04-2016 HRM2_RS05685 cc7332a3b602298c5514751350654b2d 303 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 88 296 9.9E-63 T 22-04-2016 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 HRM2_RS05685 cc7332a3b602298c5514751350654b2d 303 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 17 300 7.5E-77 T 22-04-2016 HRM2_RS05685 cc7332a3b602298c5514751350654b2d 303 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 302 31.333 T 22-04-2016 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 HRM2_RS05685 cc7332a3b602298c5514751350654b2d 303 SUPERFAMILY SSF53335 89 299 4.78E-46 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS05685 cc7332a3b602298c5514751350654b2d 303 PANTHER PTHR18895 93 299 4.2E-67 T 22-04-2016 HRM2_RS05685 cc7332a3b602298c5514751350654b2d 303 Gene3D G3DSA:3.40.50.150 119 297 4.2E-43 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS05685 cc7332a3b602298c5514751350654b2d 303 PIRSF PIRSF000401 1 303 3.9E-80 T 22-04-2016 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 HRM2_RS00465 18a9c0a68e2b34be92f3eed8074a0b63 313 SMART SM01400 5 121 1.1E-61 T 22-04-2016 HRM2_RS00465 18a9c0a68e2b34be92f3eed8074a0b63 313 SUPERFAMILY SSF53271 12 103 2.89E-7 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like HRM2_RS00465 18a9c0a68e2b34be92f3eed8074a0b63 313 PANTHER PTHR10210 1 313 4.4E-141 T 22-04-2016 HRM2_RS00465 18a9c0a68e2b34be92f3eed8074a0b63 313 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 5 121 6.6E-41 T 22-04-2016 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 HRM2_RS00465 18a9c0a68e2b34be92f3eed8074a0b63 313 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 6 313 7.8E-106 T 22-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 HRM2_RS00465 18a9c0a68e2b34be92f3eed8074a0b63 313 Gene3D G3DSA:3.40.50.2020 161 283 4.2E-42 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like HRM2_RS00465 18a9c0a68e2b34be92f3eed8074a0b63 313 SUPERFAMILY SSF53271 71 304 1.13E-49 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like HRM2_RS00465 18a9c0a68e2b34be92f3eed8074a0b63 313 Gene3D G3DSA:3.40.50.2020 1 160 1.3E-62 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like HRM2_RS00465 18a9c0a68e2b34be92f3eed8074a0b63 313 PANTHER PTHR10210:SF41 1 313 4.4E-141 T 22-04-2016 HRM2_RS00465 18a9c0a68e2b34be92f3eed8074a0b63 313 Pfam PF14572 Phosphoribosyl synthetase-associated domain 207 312 1.1E-21 T 22-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 HRM2_RS00465 18a9c0a68e2b34be92f3eed8074a0b63 313 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 129 144 - T 22-04-2016 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: REACT_474|UniPathway: UPA00087 HRM2_RS18180 97e2c966bbce3c769ecbfc4589639210 231 TIGRFAM TIGR03584 PseF: pseudaminic acid cytidylyltransferase 3 224 5.6E-101 T 22-04-2016 IPR020039 Pseudaminic acid cytidylyltransferase KEGG: 00520+2.7.7.81|MetaCyc: PWY-6143 HRM2_RS18180 97e2c966bbce3c769ecbfc4589639210 231 Pfam PF02348 Cytidylyltransferase 3 182 5.1E-36 T 22-04-2016 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|UniPathway: UPA00030|UniPathway: UPA00358 HRM2_RS18180 97e2c966bbce3c769ecbfc4589639210 231 PANTHER PTHR21485 3 220 4.8E-47 T 22-04-2016 HRM2_RS18180 97e2c966bbce3c769ecbfc4589639210 231 Gene3D G3DSA:3.90.550.10 3 225 8.7E-73 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS18180 97e2c966bbce3c769ecbfc4589639210 231 PANTHER PTHR21485:SF20 3 220 4.8E-47 T 22-04-2016 HRM2_RS18180 97e2c966bbce3c769ecbfc4589639210 231 SUPERFAMILY SSF53448 3 227 1.92E-59 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS17125 76f7a8b4e684e3de5a49c503616aec48 212 Gene3D G3DSA:3.40.50.360 4 154 2.0E-34 T 22-04-2016 IPR029039 Flavoprotein-like domain HRM2_RS17125 76f7a8b4e684e3de5a49c503616aec48 212 PANTHER PTHR10204:SF5 3 207 2.2E-18 T 22-04-2016 HRM2_RS17125 76f7a8b4e684e3de5a49c503616aec48 212 PANTHER PTHR10204 3 207 2.2E-18 T 22-04-2016 HRM2_RS17125 76f7a8b4e684e3de5a49c503616aec48 212 Pfam PF03358 NADPH-dependent FMN reductase 4 138 9.1E-18 T 22-04-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 HRM2_RS17125 76f7a8b4e684e3de5a49c503616aec48 212 SUPERFAMILY SSF52218 4 156 1.26E-24 T 22-04-2016 IPR029039 Flavoprotein-like domain HRM2_RS02630 fb0dec80585383f89d80a5a037870e13 155 PANTHER PTHR37805:SF1 1 155 2.7E-64 T 22-04-2016 HRM2_RS02630 fb0dec80585383f89d80a5a037870e13 155 PANTHER PTHR37805 1 155 2.7E-64 T 22-04-2016 HRM2_RS02630 fb0dec80585383f89d80a5a037870e13 155 Pfam PF07308 Protein of unknown function (DUF1456) 88 155 6.9E-28 T 22-04-2016 IPR009921 Domain of unknown function DUF1456 HRM2_RS02630 fb0dec80585383f89d80a5a037870e13 155 Pfam PF07308 Protein of unknown function (DUF1456) 3 70 3.4E-24 T 22-04-2016 IPR009921 Domain of unknown function DUF1456 HRM2_RS17000 9ea89cc4050e6ae40aabe8f238411137 159 SUPERFAMILY SSF64438 3 155 1.01E-40 T 22-04-2016 IPR011324 Cytotoxic necrotizing factor-like, catalytic HRM2_RS17000 9ea89cc4050e6ae40aabe8f238411137 159 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 4 155 23.123 T 22-04-2016 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 HRM2_RS17000 9ea89cc4050e6ae40aabe8f238411137 159 PANTHER PTHR35147:SF1 5 159 3.2E-33 T 22-04-2016 HRM2_RS17000 9ea89cc4050e6ae40aabe8f238411137 159 PANTHER PTHR35147 5 159 3.2E-33 T 22-04-2016 HRM2_RS17000 9ea89cc4050e6ae40aabe8f238411137 159 Pfam PF03975 CheD chemotactic sensory transduction 47 151 1.6E-26 T 22-04-2016 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 HRM2_RS12355 3d36dc837b69e5ee7bd838b985b1c13a 737 Gene3D G3DSA:3.40.50.1820 479 717 2.0E-43 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS12355 3d36dc837b69e5ee7bd838b985b1c13a 737 PANTHER PTHR11614:SF89 472 724 3.7E-34 T 22-04-2016 HRM2_RS12355 3d36dc837b69e5ee7bd838b985b1c13a 737 Pfam PF12146 Serine aminopeptidase, S33 484 698 2.4E-18 T 22-04-2016 IPR022742 Serine aminopeptidase, S33 HRM2_RS12355 3d36dc837b69e5ee7bd838b985b1c13a 737 SUPERFAMILY SSF69593 6 123 2.48E-7 T 22-04-2016 HRM2_RS12355 3d36dc837b69e5ee7bd838b985b1c13a 737 Pfam PF01553 Acyltransferase 23 149 4.3E-6 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 HRM2_RS12355 3d36dc837b69e5ee7bd838b985b1c13a 737 SUPERFAMILY SSF53474 472 718 4.02E-31 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS12355 3d36dc837b69e5ee7bd838b985b1c13a 737 PANTHER PTHR11614 472 724 3.7E-34 T 22-04-2016 HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 SMART SM00086 323 364 5.8 T 22-04-2016 IPR001610 PAC motif HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 SMART SM00086 447 489 1.6E-4 T 22-04-2016 IPR001610 PAC motif HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 PANTHER PTHR24423:SF486 35 741 1.9E-193 T 22-04-2016 HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 SUPERFAMILY SSF55874 563 733 4.85E-42 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 PRINTS PR00344 Bacterial sensor protein C-terminal signature 698 716 6.4E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 PRINTS PR00344 Bacterial sensor protein C-terminal signature 663 677 6.4E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 PRINTS PR00344 Bacterial sensor protein C-terminal signature 681 691 6.4E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 PRINTS PR00344 Bacterial sensor protein C-terminal signature 722 735 6.4E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 Pfam PF00989 PAS fold 249 361 1.3E-14 T 22-04-2016 IPR013767 PAS fold GO:0006355 HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 SUPERFAMILY SSF47384 493 576 3.14E-22 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 SMART SM00448 756 874 2.3E-25 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 SMART SM00448 907 1020 3.8E-31 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 Gene3D G3DSA:3.30.450.20 240 361 1.7E-23 T 22-04-2016 HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 Gene3D G3DSA:3.30.450.20 362 487 1.6E-22 T 22-04-2016 HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 Gene3D G3DSA:1.20.120.160 1058 1159 9.3E-15 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 Gene3D G3DSA:3.30.565.10 560 733 2.4E-41 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 SUPERFAMILY SSF55785 361 487 1.68E-21 T 22-04-2016 IPR000014 PAS domain HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 SMART SM00091 245 311 7.5E-9 T 22-04-2016 IPR000014 PAS domain HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 SMART SM00091 376 442 0.0037 T 22-04-2016 IPR000014 PAS domain HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 622 737 1.5E-27 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 Pfam PF10114 Sensory domain found in PocR 35 195 2.6E-43 T 22-04-2016 IPR018771 PocR domain UniPathway: UPA00148|UniPathway: UPA00621 HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 SUPERFAMILY SSF55785 237 362 1.4E-21 T 22-04-2016 IPR000014 PAS domain HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 Pfam PF01627 Hpt domain 1090 1173 1.1E-7 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 PANTHER PTHR24423:SF486 801 1025 1.9E-193 T 22-04-2016 HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 SMART SM00388 509 574 1.2E-25 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 Gene3D G3DSA:3.40.50.2300 751 896 6.8E-30 T 22-04-2016 HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 Gene3D G3DSA:3.40.50.2300 905 1032 2.7E-40 T 22-04-2016 HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 SUPERFAMILY SSF52172 904 1024 5.69E-37 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 Pfam PF13426 PAS domain 387 487 2.1E-11 T 22-04-2016 IPR000014 PAS domain HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 Gene3D G3DSA:1.10.287.130 501 559 3.9E-16 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 PANTHER PTHR24423 801 1025 1.9E-193 T 22-04-2016 HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 SUPERFAMILY SSF52172 754 879 2.56E-30 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 PANTHER PTHR24423 35 741 1.9E-193 T 22-04-2016 HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 Pfam PF00512 His Kinase A (phospho-acceptor) domain 509 574 8.7E-20 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 Pfam PF00072 Response regulator receiver domain 909 1019 6.2E-24 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 Pfam PF00072 Response regulator receiver domain 759 872 3.0E-19 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 SUPERFAMILY SSF47226 1066 1151 1.31E-17 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 SUPERFAMILY SSF47226 1003 1016 1.31E-17 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 SMART SM00387 622 738 5.2E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 241 371 9.0E-19 T 22-04-2016 IPR000014 PAS domain HRM2_RS21475 a3113907bd04fca41f91f7227b1085d1 1272 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 372 496 1.1E-19 T 22-04-2016 IPR000014 PAS domain HRM2_RS14565 d8965b119779a6a993881edfc20642fd 302 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 238 258 - T 22-04-2016 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 HRM2_RS14565 d8965b119779a6a993881edfc20642fd 302 Gene3D G3DSA:3.20.20.70 3 299 3.3E-89 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS14565 d8965b119779a6a993881edfc20642fd 302 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 5 298 5.5E-105 T 22-04-2016 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 HRM2_RS14565 d8965b119779a6a993881edfc20642fd 302 PIRSF PIRSF000164 1 301 1.2E-78 T 22-04-2016 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 Reactome: REACT_1698 HRM2_RS14565 d8965b119779a6a993881edfc20642fd 302 PANTHER PTHR11938 5 298 4.8E-61 T 22-04-2016 HRM2_RS14565 d8965b119779a6a993881edfc20642fd 302 Pfam PF01180 Dihydroorotate dehydrogenase 5 285 9.2E-71 T 22-04-2016 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 HRM2_RS14565 d8965b119779a6a993881edfc20642fd 302 PANTHER PTHR11938:SF5 5 298 4.8E-61 T 22-04-2016 HRM2_RS14565 d8965b119779a6a993881edfc20642fd 302 SUPERFAMILY SSF51395 2 299 1.25E-82 T 22-04-2016 HRM2_RS14565 d8965b119779a6a993881edfc20642fd 302 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 3 300 40.107 T 22-04-2016 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 HRM2_RS23455 bc4b2b0e559252ea259e718960e53004 1083 SUPERFAMILY SSF82693 48 141 1.74E-21 T 22-04-2016 HRM2_RS23455 bc4b2b0e559252ea259e718960e53004 1083 Gene3D G3DSA:1.20.1640.10 308 521 3.8E-43 T 22-04-2016 HRM2_RS23455 bc4b2b0e559252ea259e718960e53004 1083 PANTHER PTHR32063:SF16 302 886 0.0 T 22-04-2016 HRM2_RS23455 bc4b2b0e559252ea259e718960e53004 1083 PANTHER PTHR32063:SF16 9 284 0.0 T 22-04-2016 HRM2_RS23455 bc4b2b0e559252ea259e718960e53004 1083 PANTHER PTHR32063:SF16 903 1071 0.0 T 22-04-2016 HRM2_RS23455 bc4b2b0e559252ea259e718960e53004 1083 Gene3D G3DSA:3.30.2090.10 188 270 1.1E-15 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS23455 bc4b2b0e559252ea259e718960e53004 1083 Gene3D G3DSA:3.30.2090.10 750 834 4.4E-8 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS23455 bc4b2b0e559252ea259e718960e53004 1083 Gene3D G3DSA:3.30.70.1430 591 699 1.3E-9 T 22-04-2016 HRM2_RS23455 bc4b2b0e559252ea259e718960e53004 1083 SUPERFAMILY SSF82693 291 344 1.36E-8 T 22-04-2016 HRM2_RS23455 bc4b2b0e559252ea259e718960e53004 1083 SUPERFAMILY SSF82693 141 187 1.36E-8 T 22-04-2016 HRM2_RS23455 bc4b2b0e559252ea259e718960e53004 1083 Pfam PF00873 AcrB/AcrD/AcrF family 12 1066 1.5E-153 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS23455 bc4b2b0e559252ea259e718960e53004 1083 SUPERFAMILY SSF82866 313 516 3.4E-37 T 22-04-2016 HRM2_RS23455 bc4b2b0e559252ea259e718960e53004 1083 PANTHER PTHR32063 302 886 0.0 T 22-04-2016 HRM2_RS23455 bc4b2b0e559252ea259e718960e53004 1083 PANTHER PTHR32063 9 284 0.0 T 22-04-2016 HRM2_RS23455 bc4b2b0e559252ea259e718960e53004 1083 PANTHER PTHR32063 903 1071 0.0 T 22-04-2016 HRM2_RS23455 bc4b2b0e559252ea259e718960e53004 1083 SUPERFAMILY SSF82714 750 834 8.5E-8 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS23455 bc4b2b0e559252ea259e718960e53004 1083 SUPERFAMILY SSF82866 836 1070 2.22E-38 T 22-04-2016 HRM2_RS23455 bc4b2b0e559252ea259e718960e53004 1083 Gene3D G3DSA:3.30.70.1430 49 147 1.4E-20 T 22-04-2016 HRM2_RS23455 bc4b2b0e559252ea259e718960e53004 1083 SUPERFAMILY SSF82693 586 700 9.42E-11 T 22-04-2016 HRM2_RS23455 bc4b2b0e559252ea259e718960e53004 1083 PRINTS PR00702 Acriflavin resistance protein family signature 408 432 2.4E-21 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS23455 bc4b2b0e559252ea259e718960e53004 1083 PRINTS PR00702 Acriflavin resistance protein family signature 490 513 2.4E-21 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS23455 bc4b2b0e559252ea259e718960e53004 1083 PRINTS PR00702 Acriflavin resistance protein family signature 17 41 2.4E-21 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS23455 bc4b2b0e559252ea259e718960e53004 1083 PRINTS PR00702 Acriflavin resistance protein family signature 45 63 2.4E-21 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS23455 bc4b2b0e559252ea259e718960e53004 1083 PRINTS PR00702 Acriflavin resistance protein family signature 380 401 2.4E-21 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS23455 bc4b2b0e559252ea259e718960e53004 1083 Gene3D G3DSA:1.10.3850.10 841 1066 3.0E-66 T 22-04-2016 HRM2_RS23455 bc4b2b0e559252ea259e718960e53004 1083 SUPERFAMILY SSF82714 188 271 6.8E-16 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS14790 df44e61303d5e5615767b713c563bd06 665 SUPERFAMILY SSF51445 295 369 2.2E-9 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily HRM2_RS14790 df44e61303d5e5615767b713c563bd06 665 SUPERFAMILY SSF51445 21 161 2.2E-9 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily HRM2_RS14790 df44e61303d5e5615767b713c563bd06 665 SUPERFAMILY SSF51445 191 223 2.2E-9 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily HRM2_RS14790 df44e61303d5e5615767b713c563bd06 665 Gene3D G3DSA:3.20.20.80 31 370 3.7E-7 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HRM2_RS15475 74fcb99efa06d455255a7eecc31260c5 463 Gene3D G3DSA:1.10.1160.10 232 312 1.4E-31 T 22-04-2016 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: REACT_71 HRM2_RS15475 74fcb99efa06d455255a7eecc31260c5 463 PANTHER PTHR11451:SF41 1 312 3.1E-96 T 22-04-2016 HRM2_RS15475 74fcb99efa06d455255a7eecc31260c5 463 Gene3D G3DSA:3.40.50.620 3 68 3.8E-50 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS15475 74fcb99efa06d455255a7eecc31260c5 463 Gene3D G3DSA:3.40.50.620 180 229 3.8E-50 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS15475 74fcb99efa06d455255a7eecc31260c5 463 SUPERFAMILY SSF48163 298 462 3.27E-41 T 22-04-2016 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 HRM2_RS15475 74fcb99efa06d455255a7eecc31260c5 463 PRINTS PR00987 Glutamyl-tRNA synthetase signature 178 188 8.7E-25 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 HRM2_RS15475 74fcb99efa06d455255a7eecc31260c5 463 PRINTS PR00987 Glutamyl-tRNA synthetase signature 36 49 8.7E-25 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 HRM2_RS15475 74fcb99efa06d455255a7eecc31260c5 463 PRINTS PR00987 Glutamyl-tRNA synthetase signature 7 19 8.7E-25 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 HRM2_RS15475 74fcb99efa06d455255a7eecc31260c5 463 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 202 8.7E-25 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 HRM2_RS15475 74fcb99efa06d455255a7eecc31260c5 463 PRINTS PR00987 Glutamyl-tRNA synthetase signature 21 32 8.7E-25 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 HRM2_RS15475 74fcb99efa06d455255a7eecc31260c5 463 SUPERFAMILY SSF52374 4 297 4.02E-107 T 22-04-2016 HRM2_RS15475 74fcb99efa06d455255a7eecc31260c5 463 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 4 302 1.0E-98 T 22-04-2016 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 Reactome: REACT_71 HRM2_RS15475 74fcb99efa06d455255a7eecc31260c5 463 Hamap MF_00022_B Glutamate--tRNA ligase [gltX]. 4 462 33.253 T 22-04-2016 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 HRM2_RS15475 74fcb99efa06d455255a7eecc31260c5 463 Gene3D G3DSA:3.90.800.10 69 179 1.6E-37 T 22-04-2016 HRM2_RS15475 74fcb99efa06d455255a7eecc31260c5 463 Gene3D G3DSA:1.10.10.350 362 462 2.5E-28 T 22-04-2016 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 HRM2_RS15475 74fcb99efa06d455255a7eecc31260c5 463 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 21 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS15475 74fcb99efa06d455255a7eecc31260c5 463 PANTHER PTHR11451 1 312 3.1E-96 T 22-04-2016 HRM2_RS15475 74fcb99efa06d455255a7eecc31260c5 463 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 4 459 1.3E-161 T 22-04-2016 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 HRM2_RS15475 74fcb99efa06d455255a7eecc31260c5 463 Gene3D G3DSA:1.10.8.70 316 361 2.4E-6 T 22-04-2016 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 HRM2_RS04535 5aa01b49c1c20e33ae82b0f68e55af72 163 PANTHER PTHR22960 1 158 3.5E-91 T 22-04-2016 HRM2_RS04535 5aa01b49c1c20e33ae82b0f68e55af72 163 SUPERFAMILY SSF55040 11 155 7.32E-60 T 22-04-2016 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 UniPathway: UPA00344 HRM2_RS04535 5aa01b49c1c20e33ae82b0f68e55af72 163 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 152 5.0E-61 T 22-04-2016 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 UniPathway: UPA00344 HRM2_RS04535 5aa01b49c1c20e33ae82b0f68e55af72 163 Pfam PF01967 MoaC family 15 150 7.3E-54 T 22-04-2016 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 UniPathway: UPA00344 HRM2_RS04535 5aa01b49c1c20e33ae82b0f68e55af72 163 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 2 158 35.161 T 22-04-2016 IPR023046 Molybdenum cofactor biosynthesis C, bacterial-type UniPathway: UPA00344 HRM2_RS04535 5aa01b49c1c20e33ae82b0f68e55af72 163 Gene3D G3DSA:3.30.70.640 3 157 1.0E-65 T 22-04-2016 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 UniPathway: UPA00344 HRM2_RS02885 faec3d4908163b17a37b24d32a523eb7 253 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 10 244 8.7E-15 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase HRM2_RS02885 faec3d4908163b17a37b24d32a523eb7 253 PANTHER PTHR12121:SF36 2 251 8.9E-35 T 22-04-2016 HRM2_RS02885 faec3d4908163b17a37b24d32a523eb7 253 PANTHER PTHR12121 2 251 8.9E-35 T 22-04-2016 HRM2_RS02885 faec3d4908163b17a37b24d32a523eb7 253 Gene3D G3DSA:3.60.10.10 6 251 1.0E-11 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase HRM2_RS02885 faec3d4908163b17a37b24d32a523eb7 253 SUPERFAMILY SSF56219 3 251 8.38E-34 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase HRM2_RS15300 1de7ff5aee24cacf4e887e885d422dcc 172 Gene3D G3DSA:2.30.30.240 98 172 5.5E-24 T 22-04-2016 HRM2_RS15300 1de7ff5aee24cacf4e887e885d422dcc 172 PANTHER PTHR33692 8 172 3.4E-34 T 22-04-2016 HRM2_RS15300 1de7ff5aee24cacf4e887e885d422dcc 172 Gene3D G3DSA:2.40.30.60 2 92 9.7E-17 T 22-04-2016 IPR002676 RimM protein GO:0006364 HRM2_RS15300 1de7ff5aee24cacf4e887e885d422dcc 172 Pfam PF01782 RimM N-terminal domain 8 88 5.0E-17 T 22-04-2016 IPR002676 RimM protein GO:0006364 HRM2_RS15300 1de7ff5aee24cacf4e887e885d422dcc 172 SUPERFAMILY SSF50346 98 172 3.53E-19 T 22-04-2016 IPR011033 PRC-barrel-like HRM2_RS15300 1de7ff5aee24cacf4e887e885d422dcc 172 Pfam PF05239 PRC-barrel domain 96 171 2.1E-5 T 22-04-2016 IPR027275 PRC-barrel domain HRM2_RS15300 1de7ff5aee24cacf4e887e885d422dcc 172 SUPERFAMILY SSF50447 5 92 4.94E-13 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain HRM2_RS15300 1de7ff5aee24cacf4e887e885d422dcc 172 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 5 172 21.687 T 22-04-2016 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 HRM2_RS15300 1de7ff5aee24cacf4e887e885d422dcc 172 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 6 172 5.0E-37 T 22-04-2016 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 HRM2_RS00290 5640a2a9bdf19ba3a254247bb0aca4bb 245 PANTHER PTHR36438:SF1 8 242 3.5E-86 T 22-04-2016 HRM2_RS00290 5640a2a9bdf19ba3a254247bb0aca4bb 245 Pfam PF01814 Hemerythrin HHE cation binding domain 88 239 4.1E-24 T 22-04-2016 IPR012312 Haemerythrin-like HRM2_RS00290 5640a2a9bdf19ba3a254247bb0aca4bb 245 PANTHER PTHR36438 8 242 3.5E-86 T 22-04-2016 HRM2_RS00290 5640a2a9bdf19ba3a254247bb0aca4bb 245 Pfam PF04405 Domain of Unknown function (DUF542) 14 67 3.1E-23 T 22-04-2016 IPR019903 Repair of iron centres family HRM2_RS00290 5640a2a9bdf19ba3a254247bb0aca4bb 245 TIGRFAM TIGR03652 FeS_repair_RIC: iron-sulfur cluster repair di-iron protein 17 239 6.2E-74 T 22-04-2016 IPR019903 Repair of iron centres family HRM2_RS00290 5640a2a9bdf19ba3a254247bb0aca4bb 245 Gene3D G3DSA:1.20.120.520 91 240 4.1E-22 T 22-04-2016 HRM2_RS05955 d015320c2838add792a3f1bfa0516089 354 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 5 124 5.6E-17 T 22-04-2016 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain HRM2_RS05955 d015320c2838add792a3f1bfa0516089 354 PANTHER PTHR13794:SF55 1 352 1.0E-99 T 22-04-2016 HRM2_RS05955 d015320c2838add792a3f1bfa0516089 354 SMART SM00922 141 236 3.9E-9 T 22-04-2016 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal HRM2_RS05955 d015320c2838add792a3f1bfa0516089 354 Gene3D G3DSA:3.30.390.10 1 120 7.7E-32 T 22-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HRM2_RS05955 d015320c2838add792a3f1bfa0516089 354 Pfam PF13378 Enolase C-terminal domain-like 145 352 1.8E-33 T 22-04-2016 IPR029065 Enolase C-terminal domain-like HRM2_RS05955 d015320c2838add792a3f1bfa0516089 354 PANTHER PTHR13794 1 352 1.0E-99 T 22-04-2016 IPR001354 Mandelate racemase/muconate lactonizing enzyme/methylaspartate ammonia-lyase GO:0003824|GO:0008152 HRM2_RS05955 d015320c2838add792a3f1bfa0516089 354 SUPERFAMILY SSF51604 112 352 1.97E-50 T 22-04-2016 IPR029065 Enolase C-terminal domain-like HRM2_RS05955 d015320c2838add792a3f1bfa0516089 354 Gene3D G3DSA:3.20.20.120 121 351 4.2E-56 T 22-04-2016 IPR029065 Enolase C-terminal domain-like HRM2_RS05955 d015320c2838add792a3f1bfa0516089 354 SUPERFAMILY SSF54826 1 124 9.0E-26 T 22-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HRM2_RS03735 72d9f007a430e8c93d50bf3a8fd7fc03 95 Gene3D G3DSA:3.30.70.1120 1 93 1.4E-27 T 22-04-2016 IPR007546 Protein of unknown function DUF503 HRM2_RS03735 72d9f007a430e8c93d50bf3a8fd7fc03 95 Pfam PF04456 Protein of unknown function (DUF503) 3 89 2.7E-25 T 22-04-2016 IPR007546 Protein of unknown function DUF503 HRM2_RS03735 72d9f007a430e8c93d50bf3a8fd7fc03 95 SUPERFAMILY SSF103007 1 93 1.2E-24 T 22-04-2016 IPR007546 Protein of unknown function DUF503 HRM2_RS03735 72d9f007a430e8c93d50bf3a8fd7fc03 95 PANTHER PTHR36441 2 95 7.9E-19 T 22-04-2016 HRM2_RS01425 a79fd5ccaf6818e3f69af886f8f36cd9 207 SUPERFAMILY SSF48498 93 204 1.71E-16 T 22-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal HRM2_RS01425 a79fd5ccaf6818e3f69af886f8f36cd9 207 Gene3D G3DSA:1.10.357.10 71 205 6.3E-25 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HRM2_RS01425 a79fd5ccaf6818e3f69af886f8f36cd9 207 Gene3D G3DSA:1.10.10.60 22 70 7.8E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS01425 a79fd5ccaf6818e3f69af886f8f36cd9 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 69 2.3E-10 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS01425 a79fd5ccaf6818e3f69af886f8f36cd9 207 Pfam PF08359 YsiA-like protein, C-terminal region 72 203 1.7E-13 T 22-04-2016 IPR013570 Transcription regulator YsiA, C-terminal HRM2_RS01425 a79fd5ccaf6818e3f69af886f8f36cd9 207 SUPERFAMILY SSF46689 15 84 2.77E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS01425 a79fd5ccaf6818e3f69af886f8f36cd9 207 PANTHER PTHR30055:SF66 9 204 1.7E-26 T 22-04-2016 HRM2_RS01425 a79fd5ccaf6818e3f69af886f8f36cd9 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 2.5E-6 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS01425 a79fd5ccaf6818e3f69af886f8f36cd9 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 2.5E-6 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS01425 a79fd5ccaf6818e3f69af886f8f36cd9 207 PANTHER PTHR30055 9 204 1.7E-26 T 22-04-2016 HRM2_RS13105 a914a69c57fe1adae0fe2fb9f0002aa3 94 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 2 88 8.8E-11 T 22-04-2016 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit HRM2_RS13105 a914a69c57fe1adae0fe2fb9f0002aa3 94 PANTHER PTHR33362:SF7 1 88 1.0E-18 T 22-04-2016 HRM2_RS13105 a914a69c57fe1adae0fe2fb9f0002aa3 94 PANTHER PTHR33362 1 88 1.0E-18 T 22-04-2016 HRM2_RS08300 598c655b8fc73aa28c5d9712a11d616e 286 PANTHER PTHR10025:SF36 1 284 6.0E-93 T 22-04-2016 HRM2_RS08300 598c655b8fc73aa28c5d9712a11d616e 286 Gene3D G3DSA:3.40.192.10 6 140 1.7E-29 T 22-04-2016 HRM2_RS08300 598c655b8fc73aa28c5d9712a11d616e 286 Hamap MF_01576 Bifunctional protein FolD [folD]. 2 285 30.93 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 HRM2_RS08300 598c655b8fc73aa28c5d9712a11d616e 286 SUPERFAMILY SSF53223 1 121 4.32E-27 T 22-04-2016 HRM2_RS08300 598c655b8fc73aa28c5d9712a11d616e 286 SUPERFAMILY SSF51735 136 282 1.63E-39 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS08300 598c655b8fc73aa28c5d9712a11d616e 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 4.6E-48 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 HRM2_RS08300 598c655b8fc73aa28c5d9712a11d616e 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 241 257 4.6E-48 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 HRM2_RS08300 598c655b8fc73aa28c5d9712a11d616e 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 204 233 4.6E-48 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 HRM2_RS08300 598c655b8fc73aa28c5d9712a11d616e 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 155 175 4.6E-48 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 HRM2_RS08300 598c655b8fc73aa28c5d9712a11d616e 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 4.6E-48 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 HRM2_RS08300 598c655b8fc73aa28c5d9712a11d616e 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 4.6E-48 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 HRM2_RS08300 598c655b8fc73aa28c5d9712a11d616e 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 258 276 4.6E-48 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 HRM2_RS08300 598c655b8fc73aa28c5d9712a11d616e 286 Gene3D G3DSA:3.40.50.720 141 266 1.5E-50 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS08300 598c655b8fc73aa28c5d9712a11d616e 286 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 134 284 2.3E-56 T 22-04-2016 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 HRM2_RS08300 598c655b8fc73aa28c5d9712a11d616e 286 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 7.0E-28 T 22-04-2016 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 HRM2_RS08300 598c655b8fc73aa28c5d9712a11d616e 286 PANTHER PTHR10025 1 284 6.0E-93 T 22-04-2016 HRM2_RS08570 e784ffa2ce7e3a73b0620e869d4196d7 1937 Pfam PF11974 Alpha-2-macroglobulin MG1 domain 510 613 7.2E-8 T 22-04-2016 IPR021868 Alpha-2-macroglobulin MG1 domain HRM2_RS08570 e784ffa2ce7e3a73b0620e869d4196d7 1937 PANTHER PTHR40094 624 1449 8.2E-30 T 22-04-2016 HRM2_RS08570 e784ffa2ce7e3a73b0620e869d4196d7 1937 PANTHER PTHR40094 1468 1937 8.2E-30 T 22-04-2016 HRM2_RS08570 e784ffa2ce7e3a73b0620e869d4196d7 1937 Pfam PF07703 Alpha-2-macroglobulin family N-terminal region 999 1149 1.5E-13 T 22-04-2016 IPR011625 Alpha-2-macroglobulin, N-terminal 2 HRM2_RS08570 e784ffa2ce7e3a73b0620e869d4196d7 1937 SMART SM01359 998 1149 4.2E-31 T 22-04-2016 IPR011625 Alpha-2-macroglobulin, N-terminal 2 HRM2_RS08570 e784ffa2ce7e3a73b0620e869d4196d7 1937 PANTHER PTHR40094:SF1 624 1449 8.2E-30 T 22-04-2016 HRM2_RS08570 e784ffa2ce7e3a73b0620e869d4196d7 1937 PANTHER PTHR40094:SF1 1468 1937 8.2E-30 T 22-04-2016 HRM2_RS08570 e784ffa2ce7e3a73b0620e869d4196d7 1937 Pfam PF01835 MG2 domain 638 725 6.4E-12 T 22-04-2016 IPR002890 Alpha-2-macroglobulin, N-terminal GO:0004866 HRM2_RS08570 e784ffa2ce7e3a73b0620e869d4196d7 1937 Pfam PF00207 Alpha-2-macroglobulin family 1212 1299 7.8E-15 T 22-04-2016 IPR001599 Alpha-2-macroglobulin GO:0004866 HRM2_RS08570 e784ffa2ce7e3a73b0620e869d4196d7 1937 Gene3D G3DSA:1.50.10.20 1413 1706 2.6E-13 T 22-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid HRM2_RS08570 e784ffa2ce7e3a73b0620e869d4196d7 1937 SUPERFAMILY SSF48239 1411 1704 6.28E-22 T 22-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid HRM2_RS08570 e784ffa2ce7e3a73b0620e869d4196d7 1937 SMART SM01360 1211 1300 3.8E-24 T 22-04-2016 IPR001599 Alpha-2-macroglobulin GO:0004866 HRM2_RS08390 537943935cf8d9670f76b5181c232017 541 Gene3D G3DSA:3.40.309.10 307 499 5.5E-50 T 22-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 HRM2_RS08390 537943935cf8d9670f76b5181c232017 541 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 320 331 - T 22-04-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 HRM2_RS08390 537943935cf8d9670f76b5181c232017 541 PANTHER PTHR11699:SF18 23 540 1.6E-266 T 22-04-2016 HRM2_RS08390 537943935cf8d9670f76b5181c232017 541 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 292 299 - T 22-04-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 HRM2_RS08390 537943935cf8d9670f76b5181c232017 541 SUPERFAMILY SSF53720 10 526 1.44E-128 T 22-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 HRM2_RS08390 537943935cf8d9670f76b5181c232017 541 PANTHER PTHR11699 23 540 1.6E-266 T 22-04-2016 HRM2_RS08390 537943935cf8d9670f76b5181c232017 541 Pfam PF00171 Aldehyde dehydrogenase family 63 514 1.0E-108 T 22-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 HRM2_RS08390 537943935cf8d9670f76b5181c232017 541 Gene3D G3DSA:3.40.605.10 41 306 3.2E-66 T 22-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 HRM2_RS08390 537943935cf8d9670f76b5181c232017 541 TIGRFAM TIGR01236 D1pyr5carbox1: 1-pyrroline-5-carboxylate dehydrogenase 12 540 2.5E-240 T 22-04-2016 IPR005931 Delta-1-pyrroline-5-carboxylate dehydrogenase GO:0003842|GO:0006537|GO:0006561 KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853|UniPathway: UPA00261 HRM2_RS04915 1532fa0e17975310990ab746f8b94b90 377 Gene3D G3DSA:3.20.20.70 14 337 1.2E-44 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS04915 1532fa0e17975310990ab746f8b94b90 377 SUPERFAMILY SSF51569 11 342 1.0E-36 T 22-04-2016 HRM2_RS04915 1532fa0e17975310990ab746f8b94b90 377 PANTHER PTHR10277 12 268 1.2E-32 T 22-04-2016 HRM2_RS04915 1532fa0e17975310990ab746f8b94b90 377 PANTHER PTHR10277 290 339 1.2E-32 T 22-04-2016 HRM2_RS04915 1532fa0e17975310990ab746f8b94b90 377 Pfam PF00682 HMGL-like 16 318 1.0E-18 T 22-04-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 HRM2_RS04915 1532fa0e17975310990ab746f8b94b90 377 PANTHER PTHR10277:SF1 12 268 1.2E-32 T 22-04-2016 HRM2_RS04915 1532fa0e17975310990ab746f8b94b90 377 PANTHER PTHR10277:SF1 290 339 1.2E-32 T 22-04-2016 HRM2_RS23600 2be56c25a30cc4d0a0e7ef3503c011cd 315 Gene3D G3DSA:3.40.50.720 35 114 2.8E-22 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS23600 2be56c25a30cc4d0a0e7ef3503c011cd 315 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 283 5.2E-49 T 22-04-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 HRM2_RS23600 2be56c25a30cc4d0a0e7ef3503c011cd 315 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 37 311 8.1E-17 T 22-04-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 HRM2_RS23600 2be56c25a30cc4d0a0e7ef3503c011cd 315 SUPERFAMILY SSF51735 98 284 7.91E-47 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS23600 2be56c25a30cc4d0a0e7ef3503c011cd 315 SUPERFAMILY SSF52283 32 119 3.59E-19 T 22-04-2016 HRM2_RS23600 2be56c25a30cc4d0a0e7ef3503c011cd 315 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 223 239 - T 22-04-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site HRM2_RS23600 2be56c25a30cc4d0a0e7ef3503c011cd 315 PANTHER PTHR10996 36 311 3.8E-85 T 22-04-2016 HRM2_RS23600 2be56c25a30cc4d0a0e7ef3503c011cd 315 Gene3D G3DSA:3.40.50.720 115 286 3.7E-51 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS20565 99ce01002676eed6d4c5cad36cf967f4 420 SUPERFAMILY SSF53756 24 415 1.03E-64 T 22-04-2016 HRM2_RS20565 99ce01002676eed6d4c5cad36cf967f4 420 PANTHER PTHR12526 69 108 2.5E-51 T 22-04-2016 HRM2_RS20565 99ce01002676eed6d4c5cad36cf967f4 420 PANTHER PTHR12526 21 47 2.5E-51 T 22-04-2016 HRM2_RS20565 99ce01002676eed6d4c5cad36cf967f4 420 PANTHER PTHR12526 131 416 2.5E-51 T 22-04-2016 HRM2_RS20565 99ce01002676eed6d4c5cad36cf967f4 420 PANTHER PTHR12526:SF375 69 108 2.5E-51 T 22-04-2016 HRM2_RS20565 99ce01002676eed6d4c5cad36cf967f4 420 PANTHER PTHR12526:SF375 21 47 2.5E-51 T 22-04-2016 HRM2_RS20565 99ce01002676eed6d4c5cad36cf967f4 420 PANTHER PTHR12526:SF375 131 416 2.5E-51 T 22-04-2016 HRM2_RS20565 99ce01002676eed6d4c5cad36cf967f4 420 Pfam PF00534 Glycosyl transferases group 1 232 393 1.3E-33 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 HRM2_RS20565 99ce01002676eed6d4c5cad36cf967f4 420 Gene3D G3DSA:3.40.50.2000 233 393 5.0E-22 T 22-04-2016 HRM2_RS19195 eac1dfb814c19b7b0c38ee485fbbcfd5 240 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 235 4.3E-55 T 22-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 HRM2_RS19195 eac1dfb814c19b7b0c38ee485fbbcfd5 240 PANTHER PTHR11941 2 226 3.0E-71 T 22-04-2016 HRM2_RS19195 eac1dfb814c19b7b0c38ee485fbbcfd5 240 PANTHER PTHR11941:SF72 2 226 3.0E-71 T 22-04-2016 HRM2_RS19195 eac1dfb814c19b7b0c38ee485fbbcfd5 240 SUPERFAMILY SSF52096 3 233 4.02E-67 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS19195 eac1dfb814c19b7b0c38ee485fbbcfd5 240 Gene3D G3DSA:3.90.226.10 5 232 2.6E-70 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS08355 1f11dce80839322e4df4b144213ead7a 216 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 4 99 5.0E-12 T 22-04-2016 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 HRM2_RS08355 1f11dce80839322e4df4b144213ead7a 216 Gene3D G3DSA:2.170.120.20 103 194 3.1E-26 T 22-04-2016 IPR020057 Ribosomal protein L25, beta domain HRM2_RS08355 1f11dce80839322e4df4b144213ead7a 216 SUPERFAMILY SSF50715 3 193 5.41E-50 T 22-04-2016 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: REACT_71 HRM2_RS08355 1f11dce80839322e4df4b144213ead7a 216 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 187 25.494 T 22-04-2016 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 HRM2_RS08355 1f11dce80839322e4df4b144213ead7a 216 Pfam PF01386 Ribosomal L25p family 6 96 1.3E-20 T 22-04-2016 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 HRM2_RS08355 1f11dce80839322e4df4b144213ead7a 216 Gene3D G3DSA:2.40.240.10 4 99 6.7E-23 T 22-04-2016 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: REACT_71 HRM2_RS08355 1f11dce80839322e4df4b144213ead7a 216 PANTHER PTHR33284 6 212 2.1E-49 T 22-04-2016 HRM2_RS08355 1f11dce80839322e4df4b144213ead7a 216 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 6 184 3.5E-36 T 22-04-2016 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 HRM2_RS08355 1f11dce80839322e4df4b144213ead7a 216 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 104 186 8.2E-24 T 22-04-2016 IPR020057 Ribosomal protein L25, beta domain HRM2_RS19225 f572012d44aee226d27a2a59897d8d19 296 PANTHER PTHR11432 3 295 5.7E-88 T 22-04-2016 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 HRM2_RS19225 f572012d44aee226d27a2a59897d8d19 296 PANTHER PTHR11432:SF1 3 295 5.7E-88 T 22-04-2016 HRM2_RS19225 f572012d44aee226d27a2a59897d8d19 296 Pfam PF00146 NADH dehydrogenase 7 294 8.5E-32 T 22-04-2016 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 HRM2_RS16575 6345c3c22cef4e3668308e21bc4cd678 152 SMART SM00926 15 74 1.0E-12 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS16575 6345c3c22cef4e3668308e21bc4cd678 152 SUPERFAMILY SSF53706 11 135 2.22E-41 T 22-04-2016 HRM2_RS16575 6345c3c22cef4e3668308e21bc4cd678 152 PANTHER PTHR11615:SF139 1 123 7.0E-24 T 22-04-2016 HRM2_RS16575 6345c3c22cef4e3668308e21bc4cd678 152 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 15 74 2.4E-9 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS16575 6345c3c22cef4e3668308e21bc4cd678 152 Gene3D G3DSA:3.40.50.740 79 135 1.4E-15 T 22-04-2016 HRM2_RS16575 6345c3c22cef4e3668308e21bc4cd678 152 Gene3D G3DSA:2.20.25.90 13 78 1.5E-18 T 22-04-2016 HRM2_RS16575 6345c3c22cef4e3668308e21bc4cd678 152 Pfam PF00384 Molybdopterin oxidoreductase 77 127 1.3E-10 T 22-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 HRM2_RS16575 6345c3c22cef4e3668308e21bc4cd678 152 PANTHER PTHR11615 1 123 7.0E-24 T 22-04-2016 HRM2_RS08850 d9ab308e5bfbc7705a3c5ec7b6a94386 326 Pfam PF12127 SigmaW regulon antibacterial 7 318 1.5E-160 T 22-04-2016 IPR022853 Uncharacterised protein family YdfA-immunity HRM2_RS08850 d9ab308e5bfbc7705a3c5ec7b6a94386 326 Hamap MF_01562 UPF0365 protein . 1 321 47.077 T 22-04-2016 IPR022853 Uncharacterised protein family YdfA-immunity HRM2_RS08850 d9ab308e5bfbc7705a3c5ec7b6a94386 326 Gene3D G3DSA:1.10.287.40 189 283 1.9E-5 T 22-04-2016 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|UniPathway: UPA00906 HRM2_RS19030 e28af46977334b00553cf633bba96e4b 229 SUPERFAMILY SSF48008 80 211 5.75E-18 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS19030 e28af46977334b00553cf633bba96e4b 229 SMART SM00345 16 74 1.8E-5 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS19030 e28af46977334b00553cf633bba96e4b 229 Pfam PF07729 FCD domain 84 207 1.1E-14 T 22-04-2016 IPR011711 GntR, C-terminal HRM2_RS19030 e28af46977334b00553cf633bba96e4b 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 73 8.6E-9 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS19030 e28af46977334b00553cf633bba96e4b 229 Gene3D G3DSA:1.20.120.530 77 211 7.7E-19 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS19030 e28af46977334b00553cf633bba96e4b 229 SMART SM00895 84 208 8.7E-8 T 22-04-2016 IPR011711 GntR, C-terminal HRM2_RS19030 e28af46977334b00553cf633bba96e4b 229 SUPERFAMILY SSF46785 9 78 1.87E-13 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS19030 e28af46977334b00553cf633bba96e4b 229 PANTHER PTHR11751 20 101 7.5E-14 T 22-04-2016 HRM2_RS19030 e28af46977334b00553cf633bba96e4b 229 Gene3D G3DSA:1.10.10.10 3 73 3.2E-15 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS19030 e28af46977334b00553cf633bba96e4b 229 PANTHER PTHR11751:SF384 20 101 7.5E-14 T 22-04-2016 HRM2_RS03335 317a9d1640f9a36556447a7114c44fac 264 PANTHER PTHR10060 1 260 3.6E-98 T 22-04-2016 IPR001130 TatD family GO:0016788 HRM2_RS03335 317a9d1640f9a36556447a7114c44fac 264 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 3 257 2.0E-67 T 22-04-2016 IPR015991 Uncharacterised deoxyribonuclease TatD-type GO:0004536 HRM2_RS03335 317a9d1640f9a36556447a7114c44fac 264 PIRSF PIRSF005902 1 260 1.7E-72 T 22-04-2016 IPR001130 TatD family GO:0016788 HRM2_RS03335 317a9d1640f9a36556447a7114c44fac 264 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 191 207 - T 22-04-2016 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 HRM2_RS03335 317a9d1640f9a36556447a7114c44fac 264 Gene3D G3DSA:3.20.20.140 1 259 4.0E-87 T 22-04-2016 HRM2_RS03335 317a9d1640f9a36556447a7114c44fac 264 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 3 11 - T 22-04-2016 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 HRM2_RS03335 317a9d1640f9a36556447a7114c44fac 264 Pfam PF01026 TatD related DNase 4 257 5.8E-67 T 22-04-2016 IPR001130 TatD family GO:0016788 HRM2_RS03335 317a9d1640f9a36556447a7114c44fac 264 SUPERFAMILY SSF51556 3 258 2.15E-82 T 22-04-2016 IPR032466 Metal-dependent hydrolase HRM2_RS13930 b70a4918b49ce107a6f92bcd5c73630e 345 SUPERFAMILY SSF55060 199 317 3.7E-21 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain HRM2_RS13930 b70a4918b49ce107a6f92bcd5c73630e 345 SUPERFAMILY SSF54211 11 174 5.46E-22 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS13930 b70a4918b49ce107a6f92bcd5c73630e 345 Gene3D G3DSA:3.30.70.890 202 326 5.9E-24 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain HRM2_RS13930 b70a4918b49ce107a6f92bcd5c73630e 345 Gene3D G3DSA:3.30.230.10 10 172 7.6E-19 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HRM2_RS13930 b70a4918b49ce107a6f92bcd5c73630e 345 Pfam PF00288 GHMP kinases N terminal domain 102 170 1.0E-6 T 22-04-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 HRM2_RS13930 b70a4918b49ce107a6f92bcd5c73630e 345 PRINTS PR00960 LmbP protein signature 150 169 8.2E-15 T 22-04-2016 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478|UniPathway: UPA00543|UniPathway: UPA00977 HRM2_RS13930 b70a4918b49ce107a6f92bcd5c73630e 345 PRINTS PR00960 LmbP protein signature 286 305 8.2E-15 T 22-04-2016 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478|UniPathway: UPA00543|UniPathway: UPA00977 HRM2_RS13930 b70a4918b49ce107a6f92bcd5c73630e 345 PRINTS PR00960 LmbP protein signature 108 129 8.2E-15 T 22-04-2016 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478|UniPathway: UPA00543|UniPathway: UPA00977 HRM2_RS13930 b70a4918b49ce107a6f92bcd5c73630e 345 PANTHER PTHR32463 100 302 2.8E-19 T 22-04-2016 HRM2_RS13930 b70a4918b49ce107a6f92bcd5c73630e 345 Pfam PF08544 GHMP kinases C terminal 246 316 5.9E-6 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 Pfam PF00012 Hsp70 protein 4 599 2.3E-267 T 22-04-2016 IPR013126 Heat shock protein 70 family HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 SUPERFAMILY SSF100934 502 603 2.62E-20 T 22-04-2016 IPR029048 Heat shock protein 70kD, C-terminal domain HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 191 204 - T 22-04-2016 IPR018181 Heat shock protein 70, conserved site HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 Gene3D G3DSA:3.90.640.10 225 309 1.4E-30 T 22-04-2016 HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 Gene3D G3DSA:1.20.1270.10 528 598 8.5E-28 T 22-04-2016 IPR029048 Heat shock protein 70kD, C-terminal domain HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 Gene3D G3DSA:2.60.34.10 385 527 2.4E-70 T 22-04-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 22-04-2016 IPR018181 Heat shock protein 70, conserved site HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 599 1.6E-297 T 22-04-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 332 346 - T 22-04-2016 IPR018181 Heat shock protein 70, conserved site HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 PANTHER PTHR19375 2 636 0.0 T 22-04-2016 HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 PANTHER PTHR19375:SF173 2 636 0.0 T 22-04-2016 HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 Gene3D G3DSA:3.30.420.40 314 356 4.8E-38 T 22-04-2016 HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 Gene3D G3DSA:3.30.420.40 192 224 4.8E-38 T 22-04-2016 HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 SUPERFAMILY SSF53067 4 184 7.48E-65 T 22-04-2016 HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 SUPERFAMILY SSF100920 379 535 8.37E-61 T 22-04-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 SUPERFAMILY SSF53067 186 377 9.26E-69 T 22-04-2016 HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 Gene3D G3DSA:3.30.30.30 53 108 2.8E-24 T 22-04-2016 HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 632 37.491 T 22-04-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 Gene3D G3DSA:3.30.420.40 119 191 8.3E-66 T 22-04-2016 HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 Gene3D G3DSA:3.30.420.40 4 52 8.3E-66 T 22-04-2016 HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 PRINTS PR00301 70kDa heat shock protein signature 464 480 3.3E-81 T 22-04-2016 IPR013126 Heat shock protein 70 family HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 PRINTS PR00301 70kDa heat shock protein signature 31 43 3.3E-81 T 22-04-2016 IPR013126 Heat shock protein 70 family HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 PRINTS PR00301 70kDa heat shock protein signature 383 402 3.3E-81 T 22-04-2016 IPR013126 Heat shock protein 70 family HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 PRINTS PR00301 70kDa heat shock protein signature 360 380 3.3E-81 T 22-04-2016 IPR013126 Heat shock protein 70 family HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 PRINTS PR00301 70kDa heat shock protein signature 197 207 3.3E-81 T 22-04-2016 IPR013126 Heat shock protein 70 family HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 PRINTS PR00301 70kDa heat shock protein signature 138 158 3.3E-81 T 22-04-2016 IPR013126 Heat shock protein 70 family HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 PRINTS PR00301 70kDa heat shock protein signature 54 62 3.3E-81 T 22-04-2016 IPR013126 Heat shock protein 70 family HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 PRINTS PR00301 70kDa heat shock protein signature 3 16 3.3E-81 T 22-04-2016 IPR013126 Heat shock protein 70 family HRM2_RS01985 c56cfa118a9ef23a58fe43f52f2a700d 637 PRINTS PR00301 70kDa heat shock protein signature 329 345 3.3E-81 T 22-04-2016 IPR013126 Heat shock protein 70 family HRM2_RS18880 97d12fcfe93cec1d37b8c617440f7a56 301 Pfam PF00571 CBS domain 243 296 1.3E-7 T 22-04-2016 IPR000644 CBS domain HRM2_RS18880 97d12fcfe93cec1d37b8c617440f7a56 301 Pfam PF00571 CBS domain 144 204 6.4E-6 T 22-04-2016 IPR000644 CBS domain HRM2_RS18880 97d12fcfe93cec1d37b8c617440f7a56 301 Pfam PF00072 Response regulator receiver domain 7 116 5.1E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18880 97d12fcfe93cec1d37b8c617440f7a56 301 Gene3D G3DSA:3.40.50.2300 2 130 4.6E-35 T 22-04-2016 HRM2_RS18880 97d12fcfe93cec1d37b8c617440f7a56 301 SUPERFAMILY SSF54631 130 298 4.69E-23 T 22-04-2016 HRM2_RS18880 97d12fcfe93cec1d37b8c617440f7a56 301 PANTHER PTHR32071 1 175 1.4E-29 T 22-04-2016 HRM2_RS18880 97d12fcfe93cec1d37b8c617440f7a56 301 Gene3D G3DSA:3.10.580.10 133 293 3.7E-18 T 22-04-2016 HRM2_RS18880 97d12fcfe93cec1d37b8c617440f7a56 301 SUPERFAMILY SSF52172 4 122 1.57E-35 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS18880 97d12fcfe93cec1d37b8c617440f7a56 301 SMART SM00448 5 116 2.2E-31 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18880 97d12fcfe93cec1d37b8c617440f7a56 301 SMART SM00116 250 297 1.2 T 22-04-2016 IPR000644 CBS domain HRM2_RS18880 97d12fcfe93cec1d37b8c617440f7a56 301 SMART SM00116 142 205 6.0 T 22-04-2016 IPR000644 CBS domain HRM2_RS14425 f7e489cee6c5bd47f0c978ee4017f46b 638 Gene3D G3DSA:3.40.50.300 97 230 8.8E-17 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14425 f7e489cee6c5bd47f0c978ee4017f46b 638 Gene3D G3DSA:3.40.50.300 304 398 4.4E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14425 f7e489cee6c5bd47f0c978ee4017f46b 638 Pfam PF00271 Helicase conserved C-terminal domain 308 396 1.6E-4 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS14425 f7e489cee6c5bd47f0c978ee4017f46b 638 SMART SM00487 60 259 1.1E-9 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS14425 f7e489cee6c5bd47f0c978ee4017f46b 638 Pfam PF04851 Type III restriction enzyme, res subunit 93 224 1.2E-12 T 22-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HRM2_RS14425 f7e489cee6c5bd47f0c978ee4017f46b 638 PANTHER PTHR11274 97 260 1.9E-15 T 22-04-2016 HRM2_RS14425 f7e489cee6c5bd47f0c978ee4017f46b 638 SUPERFAMILY SSF52540 120 264 4.44E-25 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14425 f7e489cee6c5bd47f0c978ee4017f46b 638 SUPERFAMILY SSF52540 293 402 4.44E-25 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05415 4be0d1e17fc2df0158a44b0441687afb 455 Gene3D G3DSA:3.40.50.2300 1 124 1.0E-36 T 22-04-2016 HRM2_RS05415 4be0d1e17fc2df0158a44b0441687afb 455 Pfam PF00158 Sigma-54 interaction domain 142 307 1.1E-69 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS05415 4be0d1e17fc2df0158a44b0441687afb 455 SUPERFAMILY SSF52540 142 386 1.63E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05415 4be0d1e17fc2df0158a44b0441687afb 455 Gene3D G3DSA:3.40.50.300 139 314 8.5E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05415 4be0d1e17fc2df0158a44b0441687afb 455 SUPERFAMILY SSF52172 2 186 6.12E-46 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS05415 4be0d1e17fc2df0158a44b0441687afb 455 Gene3D G3DSA:1.10.10.60 398 454 9.6E-16 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS05415 4be0d1e17fc2df0158a44b0441687afb 455 SUPERFAMILY SSF46689 357 454 1.7E-15 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS05415 4be0d1e17fc2df0158a44b0441687afb 455 PANTHER PTHR32071 1 454 3.9E-204 T 22-04-2016 HRM2_RS05415 4be0d1e17fc2df0158a44b0441687afb 455 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 357 366 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS05415 4be0d1e17fc2df0158a44b0441687afb 455 Pfam PF00072 Response regulator receiver domain 4 113 2.6E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS05415 4be0d1e17fc2df0158a44b0441687afb 455 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 418 435 5.0E-8 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS05415 4be0d1e17fc2df0158a44b0441687afb 455 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 435 455 5.0E-8 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS05415 4be0d1e17fc2df0158a44b0441687afb 455 SMART SM00448 2 113 3.0E-33 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS05415 4be0d1e17fc2df0158a44b0441687afb 455 Gene3D G3DSA:1.10.8.60 315 395 5.5E-26 T 22-04-2016 HRM2_RS05415 4be0d1e17fc2df0158a44b0441687afb 455 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 166 179 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS05415 4be0d1e17fc2df0158a44b0441687afb 455 SMART SM00382 162 305 2.2E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS05415 4be0d1e17fc2df0158a44b0441687afb 455 Pfam PF02954 Bacterial regulatory protein, Fis family 412 452 7.5E-11 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS25470 f35053cd4dc7e6066ade4610ae96ad90 428 SMART SM00028 279 312 21.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS25470 f35053cd4dc7e6066ade4610ae96ad90 428 SMART SM00028 245 278 2.8 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS25470 f35053cd4dc7e6066ade4610ae96ad90 428 SMART SM00028 313 346 0.58 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS25470 f35053cd4dc7e6066ade4610ae96ad90 428 SMART SM00028 347 381 490.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS25470 f35053cd4dc7e6066ade4610ae96ad90 428 SMART SM00028 211 244 1.8 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS25470 f35053cd4dc7e6066ade4610ae96ad90 428 SMART SM00028 382 415 140.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS25470 f35053cd4dc7e6066ade4610ae96ad90 428 PANTHER PTHR23083 187 406 4.9E-40 T 22-04-2016 HRM2_RS25470 f35053cd4dc7e6066ade4610ae96ad90 428 Pfam PF13181 Tetratricopeptide repeat 319 346 0.077 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS25470 f35053cd4dc7e6066ade4610ae96ad90 428 Pfam PF13181 Tetratricopeptide repeat 249 276 0.013 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS25470 f35053cd4dc7e6066ade4610ae96ad90 428 SUPERFAMILY SSF48452 151 406 3.15E-30 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS25470 f35053cd4dc7e6066ade4610ae96ad90 428 Gene3D G3DSA:1.25.40.10 183 298 3.7E-24 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS25470 f35053cd4dc7e6066ade4610ae96ad90 428 Gene3D G3DSA:1.25.40.10 299 406 6.7E-19 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS22440 e2e9876e15cf0d0fc4a367d6f22e2d0b 325 Gene3D G3DSA:3.40.50.300 6 258 2.1E-72 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22440 e2e9876e15cf0d0fc4a367d6f22e2d0b 325 PANTHER PTHR24220:SF493 8 319 8.1E-167 T 22-04-2016 HRM2_RS22440 e2e9876e15cf0d0fc4a367d6f22e2d0b 325 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 301 1.6E-16 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HRM2_RS22440 e2e9876e15cf0d0fc4a367d6f22e2d0b 325 Pfam PF00005 ABC transporter 33 184 5.1E-30 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS22440 e2e9876e15cf0d0fc4a367d6f22e2d0b 325 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 236 319 6.2E-25 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HRM2_RS22440 e2e9876e15cf0d0fc4a367d6f22e2d0b 325 SUPERFAMILY SSF52540 9 255 1.16E-65 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22440 e2e9876e15cf0d0fc4a367d6f22e2d0b 325 SMART SM00382 42 234 4.4E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS22440 e2e9876e15cf0d0fc4a367d6f22e2d0b 325 PANTHER PTHR24220 8 319 8.1E-167 T 22-04-2016 HRM2_RS22440 e2e9876e15cf0d0fc4a367d6f22e2d0b 325 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS06520 97203f85763c0132911898dd0f892c63 92 Pfam PF05488 PAAR motif 7 81 7.4E-23 T 22-04-2016 IPR008727 PAAR motif HRM2_RS06305 6a9bfd28cfebdd100da07828b1500293 369 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 2 359 1.8E-83 T 22-04-2016 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HRM2_RS06305 6a9bfd28cfebdd100da07828b1500293 369 Gene3D G3DSA:3.40.50.2000 2 204 2.1E-54 T 22-04-2016 HRM2_RS06305 6a9bfd28cfebdd100da07828b1500293 369 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 7 146 1.3E-28 T 22-04-2016 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HRM2_RS06305 6a9bfd28cfebdd100da07828b1500293 369 PANTHER PTHR21015:SF22 2 367 7.5E-101 T 22-04-2016 HRM2_RS06305 6a9bfd28cfebdd100da07828b1500293 369 PANTHER PTHR21015 2 367 7.5E-101 T 22-04-2016 HRM2_RS06305 6a9bfd28cfebdd100da07828b1500293 369 SUPERFAMILY SSF53756 6 365 6.04E-101 T 22-04-2016 HRM2_RS06305 6a9bfd28cfebdd100da07828b1500293 369 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 192 347 6.1E-38 T 22-04-2016 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HRM2_RS06305 6a9bfd28cfebdd100da07828b1500293 369 Gene3D G3DSA:3.40.50.2000 261 340 9.9E-7 T 22-04-2016 HRM2_RS06305 6a9bfd28cfebdd100da07828b1500293 369 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 7 364 31.559 T 22-04-2016 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HRM2_RS10995 468f8d36833f8b0b1bbc148194182dd0 389 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 12 389 3.0E-90 T 22-04-2016 HRM2_RS10995 468f8d36833f8b0b1bbc148194182dd0 389 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 2 389 8.5E-144 T 22-04-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 HRM2_RS10995 468f8d36833f8b0b1bbc148194182dd0 389 SUPERFAMILY SSF56266 2 386 8.37E-136 T 22-04-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 HRM2_RS10995 468f8d36833f8b0b1bbc148194182dd0 389 Pfam PF01960 ArgJ family 6 389 3.4E-147 T 22-04-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 HRM2_RS10995 468f8d36833f8b0b1bbc148194182dd0 389 PANTHER PTHR23100 2 389 1.1E-184 T 22-04-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 HRM2_RS10995 468f8d36833f8b0b1bbc148194182dd0 389 PANTHER PTHR23100:SF0 2 389 1.1E-184 T 22-04-2016 HRM2_RS10995 468f8d36833f8b0b1bbc148194182dd0 389 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 389 140.592 T 22-04-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 HRM2_RS10995 468f8d36833f8b0b1bbc148194182dd0 389 Gene3D G3DSA:3.60.70.12 2 261 3.6E-99 T 22-04-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 HRM2_RS24415 efdba65a997977fef5feff8ec6817428 720 SUPERFAMILY SSF52540 536 695 9.74E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24415 efdba65a997977fef5feff8ec6817428 720 SUPERFAMILY SSF52540 426 493 9.74E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24415 efdba65a997977fef5feff8ec6817428 720 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 1 713 26.506 T 22-04-2016 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 HRM2_RS24415 efdba65a997977fef5feff8ec6817428 720 Gene3D G3DSA:3.40.50.300 279 498 1.9E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24415 efdba65a997977fef5feff8ec6817428 720 Gene3D G3DSA:3.40.50.300 627 686 5.8E-12 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24415 efdba65a997977fef5feff8ec6817428 720 Gene3D G3DSA:3.40.50.300 503 569 5.8E-12 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24415 efdba65a997977fef5feff8ec6817428 720 Pfam PF14490 Helix-hairpin-helix containing domain 141 230 4.2E-24 T 22-04-2016 IPR029493 RecD helicase-like helix-hairpin-helix domain HRM2_RS24415 efdba65a997977fef5feff8ec6817428 720 PANTHER PTHR10887:SF284 266 571 7.8E-92 T 22-04-2016 HRM2_RS24415 efdba65a997977fef5feff8ec6817428 720 PANTHER PTHR10887:SF284 635 696 7.8E-92 T 22-04-2016 HRM2_RS24415 efdba65a997977fef5feff8ec6817428 720 Pfam PF13604 AAA domain 317 495 4.1E-42 T 22-04-2016 HRM2_RS24415 efdba65a997977fef5feff8ec6817428 720 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 4 708 2.6E-209 T 22-04-2016 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 HRM2_RS24415 efdba65a997977fef5feff8ec6817428 720 SUPERFAMILY SSF52540 180 475 3.66E-40 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24415 efdba65a997977fef5feff8ec6817428 720 PANTHER PTHR10887 266 571 7.8E-92 T 22-04-2016 HRM2_RS24415 efdba65a997977fef5feff8ec6817428 720 PANTHER PTHR10887 635 696 7.8E-92 T 22-04-2016 HRM2_RS24415 efdba65a997977fef5feff8ec6817428 720 Pfam PF14520 Helix-hairpin-helix domain 90 138 2.5E-7 T 22-04-2016 HRM2_RS24415 efdba65a997977fef5feff8ec6817428 720 SMART SM00382 330 478 5.7E-5 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS24415 efdba65a997977fef5feff8ec6817428 720 Gene3D G3DSA:1.10.150.20 90 156 7.0E-5 T 22-04-2016 HRM2_RS24415 efdba65a997977fef5feff8ec6817428 720 Hamap MF_01487 RecBCD enzyme subunit RecD [recD]. 186 708 28.184 T 22-04-2016 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 HRM2_RS24415 efdba65a997977fef5feff8ec6817428 720 SUPERFAMILY SSF47781 90 157 2.06E-8 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 HRM2_RS24415 efdba65a997977fef5feff8ec6817428 720 Pfam PF13538 UvrD-like helicase C-terminal domain 635 682 3.6E-16 T 22-04-2016 IPR027785 UvrD-like helicase C-terminal domain HRM2_RS25160 d24727f0d123f2bb1bb4d2c2c13b32ae 571 Gene3D G3DSA:3.30.450.20 212 327 9.7E-17 T 22-04-2016 HRM2_RS25160 d24727f0d123f2bb1bb4d2c2c13b32ae 571 SUPERFAMILY SSF109604 340 540 7.85E-38 T 22-04-2016 HRM2_RS25160 d24727f0d123f2bb1bb4d2c2c13b32ae 571 Gene3D G3DSA:1.10.3210.10 361 544 1.1E-20 T 22-04-2016 IPR006674 HD domain HRM2_RS25160 d24727f0d123f2bb1bb4d2c2c13b32ae 571 SUPERFAMILY SSF55785 202 327 9.99E-16 T 22-04-2016 IPR000014 PAS domain HRM2_RS25160 d24727f0d123f2bb1bb4d2c2c13b32ae 571 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 211 336 1.3E-15 T 22-04-2016 IPR000014 PAS domain HRM2_RS25160 d24727f0d123f2bb1bb4d2c2c13b32ae 571 Pfam PF00989 PAS fold 216 326 1.5E-7 T 22-04-2016 IPR013767 PAS fold GO:0006355 HRM2_RS25160 d24727f0d123f2bb1bb4d2c2c13b32ae 571 SMART SM00471 361 511 6.9E-8 T 22-04-2016 IPR003607 HD/PDEase domain HRM2_RS25160 d24727f0d123f2bb1bb4d2c2c13b32ae 571 Pfam PF13487 HD domain 424 493 6.3E-16 T 22-04-2016 HRM2_RS25160 d24727f0d123f2bb1bb4d2c2c13b32ae 571 SMART SM00091 215 281 3.5E-5 T 22-04-2016 IPR000014 PAS domain HRM2_RS11290 f2e1448db0d7137ad9b6f3fa7d11d702 175 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 58 69 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS11290 f2e1448db0d7137ad9b6f3fa7d11d702 175 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 14 25 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS11290 f2e1448db0d7137ad9b6f3fa7d11d702 175 SUPERFAMILY SSF46548 9 88 1.71E-14 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS11290 f2e1448db0d7137ad9b6f3fa7d11d702 175 Gene3D G3DSA:1.10.1060.10 8 91 1.5E-11 T 22-04-2016 HRM2_RS11290 f2e1448db0d7137ad9b6f3fa7d11d702 175 Pfam PF13534 4Fe-4S dicluster domain 14 73 6.5E-11 T 22-04-2016 HRM2_RS15250 f604aa144299210f446b28bab6bdff6e 65 Gene3D G3DSA:3.50.50.60 15 64 1.7E-15 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS15250 f604aa144299210f446b28bab6bdff6e 65 PANTHER PTHR10742:SF263 15 65 5.1E-20 T 22-04-2016 HRM2_RS15250 f604aa144299210f446b28bab6bdff6e 65 Pfam PF12831 FAD dependent oxidoreductase 15 52 1.0E-7 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS15250 f604aa144299210f446b28bab6bdff6e 65 PANTHER PTHR10742 15 65 5.1E-20 T 22-04-2016 HRM2_RS15250 f604aa144299210f446b28bab6bdff6e 65 SUPERFAMILY SSF51971 15 62 2.59E-9 T 22-04-2016 HRM2_RS15845 13dd5c0a3f1655d124a3ac97f6931b9a 197 Hamap MF_00478 Electron transport complex subunit RsxE [rsxE]. 1 197 24.714 T 22-04-2016 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 HRM2_RS15845 13dd5c0a3f1655d124a3ac97f6931b9a 197 PIRSF PIRSF006102 1 197 2.4E-69 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 HRM2_RS15845 13dd5c0a3f1655d124a3ac97f6931b9a 197 TIGRFAM TIGR01948 rnfE: electron transport complex, RnfABCDGE type, E subunit 7 196 9.4E-72 T 22-04-2016 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 HRM2_RS15845 13dd5c0a3f1655d124a3ac97f6931b9a 197 PANTHER PTHR30586:SF0 1 197 1.1E-92 T 22-04-2016 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 HRM2_RS15845 13dd5c0a3f1655d124a3ac97f6931b9a 197 Pfam PF02508 Rnf-Nqr subunit, membrane protein 6 187 7.5E-64 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 HRM2_RS15845 13dd5c0a3f1655d124a3ac97f6931b9a 197 PANTHER PTHR30586 1 197 1.1E-92 T 22-04-2016 HRM2_RS11130 bc703a2be7cfedea80fa174a19328cdc 396 PANTHER PTHR30372:SF0 7 392 3.9E-104 T 22-04-2016 HRM2_RS11130 bc703a2be7cfedea80fa174a19328cdc 396 Pfam PF02684 Lipid-A-disaccharide synthetase 15 353 1.5E-87 T 22-04-2016 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00359 HRM2_RS11130 bc703a2be7cfedea80fa174a19328cdc 396 Gene3D G3DSA:3.40.50.2000 168 361 2.8E-6 T 22-04-2016 HRM2_RS11130 bc703a2be7cfedea80fa174a19328cdc 396 SUPERFAMILY SSF53756 14 385 5.76E-31 T 22-04-2016 HRM2_RS11130 bc703a2be7cfedea80fa174a19328cdc 396 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 11 384 1.9E-81 T 22-04-2016 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00359 HRM2_RS11130 bc703a2be7cfedea80fa174a19328cdc 396 PANTHER PTHR30372 7 392 3.9E-104 T 22-04-2016 HRM2_RS14125 092f3ffacc29e1de1b3a8b5b72d7e4c1 324 Gene3D G3DSA:2.60.260.20 249 321 9.2E-8 T 22-04-2016 HRM2_RS14125 092f3ffacc29e1de1b3a8b5b72d7e4c1 324 SUPERFAMILY SSF49493 250 321 1.02E-8 T 22-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 HRM2_RS14125 092f3ffacc29e1de1b3a8b5b72d7e4c1 324 Pfam PF01556 DnaJ C terminal domain 257 320 4.0E-6 T 22-04-2016 IPR002939 Chaperone DnaJ, C-terminal HRM2_RS14125 092f3ffacc29e1de1b3a8b5b72d7e4c1 324 SUPERFAMILY SSF144091 11 214 1.05E-39 T 22-04-2016 HRM2_RS14125 092f3ffacc29e1de1b3a8b5b72d7e4c1 324 Pfam PF01694 Rhomboid family 69 213 7.5E-36 T 22-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 HRM2_RS14125 092f3ffacc29e1de1b3a8b5b72d7e4c1 324 PANTHER PTHR22936 1 212 3.4E-36 T 22-04-2016 IPR002610 Peptidase S54, rhomboid GO:0004252|GO:0006508|GO:0016021 HRM2_RS14125 092f3ffacc29e1de1b3a8b5b72d7e4c1 324 Gene3D G3DSA:1.20.1540.10 13 212 2.0E-41 T 22-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 HRM2_RS18605 83c343cf6b978d02d928fb82821facb8 268 Gene3D G3DSA:3.90.850.10 46 267 7.2E-91 T 22-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 HRM2_RS18605 83c343cf6b978d02d928fb82821facb8 268 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 56 265 1.0E-71 T 22-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 HRM2_RS18605 83c343cf6b978d02d928fb82821facb8 268 PANTHER PTHR11820:SF6 46 268 9.4E-111 T 22-04-2016 HRM2_RS18605 83c343cf6b978d02d928fb82821facb8 268 SUPERFAMILY SSF56529 48 267 5.49E-80 T 22-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 HRM2_RS18605 83c343cf6b978d02d928fb82821facb8 268 PANTHER PTHR11820 46 268 9.4E-111 T 22-04-2016 HRM2_RS02995 943379a05df9398f134c6bd646f7b063 401 PANTHER PTHR11808 8 401 3.6E-178 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 HRM2_RS02995 943379a05df9398f134c6bd646f7b063 401 Gene3D G3DSA:3.40.640.10 10 262 3.5E-93 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS02995 943379a05df9398f134c6bd646f7b063 401 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 11 396 2.3E-138 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 HRM2_RS02995 943379a05df9398f134c6bd646f7b063 401 SUPERFAMILY SSF53383 29 396 6.05E-120 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS02995 943379a05df9398f134c6bd646f7b063 401 PIRSF PIRSF001434 1 400 5.3E-143 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 HRM2_RS02995 943379a05df9398f134c6bd646f7b063 401 Gene3D G3DSA:3.90.1150.10 264 397 1.6E-52 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS25325 5d2dc0a88faa6ec097922223514810c8 192 SUPERFAMILY SSF54523 14 106 1.02E-16 T 22-04-2016 HRM2_RS25325 5d2dc0a88faa6ec097922223514810c8 192 Pfam PF12019 Type II transport protein GspH 49 178 4.7E-8 T 22-04-2016 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 HRM2_RS25325 5d2dc0a88faa6ec097922223514810c8 192 Pfam PF13633 Prokaryotic N-terminal methylation site 13 36 2.4E-9 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site HRM2_RS25325 5d2dc0a88faa6ec097922223514810c8 192 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 13 34 1.2E-8 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site HRM2_RS25325 5d2dc0a88faa6ec097922223514810c8 192 Gene3D G3DSA:3.30.700.10 14 63 3.3E-8 T 22-04-2016 HRM2_RS08145 92b833daff9b18ca9b064fe1e2fb8548 576 Gene3D G3DSA:3.10.580.10 442 564 9.1E-22 T 22-04-2016 HRM2_RS08145 92b833daff9b18ca9b064fe1e2fb8548 576 SUPERFAMILY SSF54631 437 563 8.59E-25 T 22-04-2016 HRM2_RS08145 92b833daff9b18ca9b064fe1e2fb8548 576 PANTHER PTHR11689:SF14 12 569 5.3E-98 T 22-04-2016 HRM2_RS08145 92b833daff9b18ca9b064fe1e2fb8548 576 Gene3D G3DSA:1.10.3080.10 20 429 1.5E-72 T 22-04-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 HRM2_RS08145 92b833daff9b18ca9b064fe1e2fb8548 576 Pfam PF00571 CBS domain 446 499 0.0076 T 22-04-2016 IPR000644 CBS domain HRM2_RS08145 92b833daff9b18ca9b064fe1e2fb8548 576 Pfam PF00571 CBS domain 511 563 1.5E-8 T 22-04-2016 IPR000644 CBS domain HRM2_RS08145 92b833daff9b18ca9b064fe1e2fb8548 576 Pfam PF00654 Voltage gated chloride channel 69 411 1.1E-72 T 22-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HRM2_RS08145 92b833daff9b18ca9b064fe1e2fb8548 576 SMART SM00116 452 501 0.079 T 22-04-2016 IPR000644 CBS domain HRM2_RS08145 92b833daff9b18ca9b064fe1e2fb8548 576 SMART SM00116 518 565 1.4 T 22-04-2016 IPR000644 CBS domain HRM2_RS08145 92b833daff9b18ca9b064fe1e2fb8548 576 SUPERFAMILY SSF81340 7 428 6.93E-88 T 22-04-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 HRM2_RS08145 92b833daff9b18ca9b064fe1e2fb8548 576 PANTHER PTHR11689 12 569 5.3E-98 T 22-04-2016 HRM2_RS08145 92b833daff9b18ca9b064fe1e2fb8548 576 PRINTS PR00762 Chloride channel signature 326 346 3.5E-17 T 22-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HRM2_RS08145 92b833daff9b18ca9b064fe1e2fb8548 576 PRINTS PR00762 Chloride channel signature 362 378 3.5E-17 T 22-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HRM2_RS08145 92b833daff9b18ca9b064fe1e2fb8548 576 PRINTS PR00762 Chloride channel signature 162 181 3.5E-17 T 22-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HRM2_RS08145 92b833daff9b18ca9b064fe1e2fb8548 576 PRINTS PR00762 Chloride channel signature 82 99 3.5E-17 T 22-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HRM2_RS08145 92b833daff9b18ca9b064fe1e2fb8548 576 PRINTS PR00762 Chloride channel signature 380 399 3.5E-17 T 22-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HRM2_RS16295 99171b2123d6727e0660c2d62e47339c 367 PANTHER PTHR30518:SF2 23 363 3.7E-95 T 22-04-2016 HRM2_RS16295 99171b2123d6727e0660c2d62e47339c 367 Gene3D G3DSA:3.30.160.60 335 365 2.1E-14 T 22-04-2016 IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain GO:0003676 HRM2_RS16295 99171b2123d6727e0660c2d62e47339c 367 Pfam PF02618 YceG-like family 77 361 1.3E-86 T 22-04-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like HRM2_RS16295 99171b2123d6727e0660c2d62e47339c 367 PANTHER PTHR30518 23 363 3.7E-95 T 22-04-2016 HRM2_RS16295 99171b2123d6727e0660c2d62e47339c 367 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 35 363 7.4E-87 T 22-04-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like HRM2_RS06390 1aa6c4e54304f2b0e125468edf5676ae 320 PANTHER PTHR18640:SF9 44 314 8.2E-31 T 22-04-2016 HRM2_RS06390 1aa6c4e54304f2b0e125468edf5676ae 320 PANTHER PTHR18640 44 314 8.2E-31 T 22-04-2016 IPR016833 Putative sodium bile acid cotransporter HRM2_RS06390 1aa6c4e54304f2b0e125468edf5676ae 320 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 8 316 5.4E-58 T 22-04-2016 IPR016833 Putative sodium bile acid cotransporter HRM2_RS09130 b25705372e05f23e183b9b2892a186e2 242 PANTHER PTHR12677 87 194 3.8E-20 T 22-04-2016 IPR015414 Transmembrane protein TMEM64/TMEM41 GO:0016021 HRM2_RS09130 b25705372e05f23e183b9b2892a186e2 242 Pfam PF09335 SNARE associated Golgi protein 79 195 7.5E-20 T 22-04-2016 IPR032816 SNARE associated Golgi protein HRM2_RS11600 f8d67bcb665d89b46a3aa365c5f56d37 753 Gene3D G3DSA:3.90.199.10 35 241 2.3E-100 T 22-04-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 HRM2_RS11600 f8d67bcb665d89b46a3aa365c5f56d37 753 Gene3D G3DSA:3.90.199.10 336 401 2.3E-100 T 22-04-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 HRM2_RS11600 f8d67bcb665d89b46a3aa365c5f56d37 753 Gene3D G3DSA:3.30.1360.40 242 334 9.7E-22 T 22-04-2016 IPR024946 Arginine repressor C-terminal-like domain HRM2_RS11600 f8d67bcb665d89b46a3aa365c5f56d37 753 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 36 470 8.3E-131 T 22-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS11600 f8d67bcb665d89b46a3aa365c5f56d37 753 SUPERFAMILY SSF101904 504 747 8.24E-42 T 22-04-2016 HRM2_RS11600 f8d67bcb665d89b46a3aa365c5f56d37 753 PANTHER PTHR10169 8 527 0.0 T 22-04-2016 HRM2_RS11600 f8d67bcb665d89b46a3aa365c5f56d37 753 PANTHER PTHR10169:SF30 8 527 0.0 T 22-04-2016 HRM2_RS11600 f8d67bcb665d89b46a3aa365c5f56d37 753 Gene3D G3DSA:2.120.10.90 497 738 7.3E-22 T 22-04-2016 HRM2_RS11600 f8d67bcb665d89b46a3aa365c5f56d37 753 SUPERFAMILY SSF56719 35 486 2.09E-149 T 22-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 HRM2_RS11600 f8d67bcb665d89b46a3aa365c5f56d37 753 SMART SM00434 15 464 9.6E-211 T 22-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS11600 f8d67bcb665d89b46a3aa365c5f56d37 753 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 8 747 31.682 T 22-04-2016 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HRM2_RS11600 f8d67bcb665d89b46a3aa365c5f56d37 753 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 13 746 0.0 T 22-04-2016 HRM2_RS22695 353512c150fb8cbfbab6a9a689152105 514 PANTHER PTHR30047:SF2 12 513 1.3E-170 T 22-04-2016 HRM2_RS22695 353512c150fb8cbfbab6a9a689152105 514 PANTHER PTHR30047 12 513 1.3E-170 T 22-04-2016 HRM2_RS22695 353512c150fb8cbfbab6a9a689152105 514 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 62 510 1.0E-131 T 22-04-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 HRM2_RS22695 353512c150fb8cbfbab6a9a689152105 514 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 24 510 4.6E-165 T 22-04-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 HRM2_RS07155 2b818ae2fc22c9ee6307ff250aef292b 282 Pfam PF00037 4Fe-4S binding domain 208 224 1.6E-5 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS07155 2b818ae2fc22c9ee6307ff250aef292b 282 Gene3D G3DSA:1.10.1060.10 151 239 1.8E-12 T 22-04-2016 HRM2_RS07155 2b818ae2fc22c9ee6307ff250aef292b 282 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 210 221 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS07155 2b818ae2fc22c9ee6307ff250aef292b 282 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 160 171 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS07155 2b818ae2fc22c9ee6307ff250aef292b 282 SUPERFAMILY SSF46548 152 242 1.26E-15 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS20765 5084dbe8001e12f0dd2fe65603bece69 273 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 113 133 - T 22-04-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 HRM2_RS20765 5084dbe8001e12f0dd2fe65603bece69 273 Gene3D G3DSA:3.90.226.10 2 213 8.2E-63 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS20765 5084dbe8001e12f0dd2fe65603bece69 273 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 272 4.6E-51 T 22-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 HRM2_RS20765 5084dbe8001e12f0dd2fe65603bece69 273 PANTHER PTHR11941:SF43 2 270 2.2E-112 T 22-04-2016 HRM2_RS20765 5084dbe8001e12f0dd2fe65603bece69 273 Gene3D G3DSA:1.10.12.10 215 272 1.2E-20 T 22-04-2016 IPR014748 Crontonase, C-terminal HRM2_RS20765 5084dbe8001e12f0dd2fe65603bece69 273 PANTHER PTHR11941 2 270 2.2E-112 T 22-04-2016 HRM2_RS20765 5084dbe8001e12f0dd2fe65603bece69 273 SUPERFAMILY SSF52096 3 272 1.23E-75 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS02370 37ffb95665b53707d3f3dcbbdf4a366d 168 Gene3D G3DSA:3.40.50.300 3 161 1.2E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02370 37ffb95665b53707d3f3dcbbdf4a366d 168 PANTHER PTHR40072 5 114 2.3E-26 T 22-04-2016 HRM2_RS02370 37ffb95665b53707d3f3dcbbdf4a366d 168 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 6 135 8.3E-51 T 22-04-2016 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 HRM2_RS02370 37ffb95665b53707d3f3dcbbdf4a366d 168 PANTHER PTHR40072:SF2 5 114 2.3E-26 T 22-04-2016 HRM2_RS02370 37ffb95665b53707d3f3dcbbdf4a366d 168 SUPERFAMILY SSF52540 3 157 1.65E-23 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02370 37ffb95665b53707d3f3dcbbdf4a366d 168 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 6 159 3.9E-43 T 22-04-2016 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 HRM2_RS19970 b615585a950d4313708337dbd4156565 905 Gene3D G3DSA:3.40.50.300 427 543 2.7E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19970 b615585a950d4313708337dbd4156565 905 Gene3D G3DSA:3.40.50.300 166 310 2.5E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19970 b615585a950d4313708337dbd4156565 905 SMART SM00487 144 341 2.3E-21 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS19970 b615585a950d4313708337dbd4156565 905 SMART SM00490 430 538 4.4E-8 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS19970 b615585a950d4313708337dbd4156565 905 Pfam PF00176 SNF2 family N-terminal domain 168 337 1.3E-16 T 22-04-2016 IPR000330 SNF2-related, N-terminal domain GO:0005524 HRM2_RS19970 b615585a950d4313708337dbd4156565 905 Pfam PF12137 RNA polymerase recycling family C-terminal 543 902 1.1E-107 T 22-04-2016 IPR022737 RNA polymerase recycling, bacterial, C-terminal GO:0016817 HRM2_RS19970 b615585a950d4313708337dbd4156565 905 SUPERFAMILY SSF52540 418 580 5.79E-35 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19970 b615585a950d4313708337dbd4156565 905 SUPERFAMILY SSF52540 269 329 5.79E-35 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19970 b615585a950d4313708337dbd4156565 905 PANTHER PTHR10799 752 856 3.5E-130 T 22-04-2016 HRM2_RS19970 b615585a950d4313708337dbd4156565 905 PANTHER PTHR10799 714 727 3.5E-130 T 22-04-2016 HRM2_RS19970 b615585a950d4313708337dbd4156565 905 PANTHER PTHR10799 106 636 3.5E-130 T 22-04-2016 HRM2_RS19970 b615585a950d4313708337dbd4156565 905 SUPERFAMILY SSF52540 120 340 1.1E-32 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19970 b615585a950d4313708337dbd4156565 905 PANTHER PTHR10799:SF610 752 856 3.5E-130 T 22-04-2016 HRM2_RS19970 b615585a950d4313708337dbd4156565 905 PANTHER PTHR10799:SF610 714 727 3.5E-130 T 22-04-2016 HRM2_RS19970 b615585a950d4313708337dbd4156565 905 PANTHER PTHR10799:SF610 106 636 3.5E-130 T 22-04-2016 HRM2_RS19970 b615585a950d4313708337dbd4156565 905 Pfam PF00271 Helicase conserved C-terminal domain 428 538 2.1E-12 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS22965 ebcd3051f87e51e0b1685cbecaeb1e13 662 Pfam PF13487 HD domain 529 598 1.2E-16 T 22-04-2016 HRM2_RS22965 ebcd3051f87e51e0b1685cbecaeb1e13 662 Gene3D G3DSA:1.10.3210.10 466 648 1.8E-18 T 22-04-2016 IPR006674 HD domain HRM2_RS22965 ebcd3051f87e51e0b1685cbecaeb1e13 662 SUPERFAMILY SSF109604 457 645 5.97E-33 T 22-04-2016 HRM2_RS22965 ebcd3051f87e51e0b1685cbecaeb1e13 662 SMART SM00471 466 616 4.2E-9 T 22-04-2016 IPR003607 HD/PDEase domain HRM2_RS22965 ebcd3051f87e51e0b1685cbecaeb1e13 662 Pfam PF05226 CHASE2 domain 28 372 2.4E-52 T 22-04-2016 IPR007890 CHASE2 HRM2_RS22965 ebcd3051f87e51e0b1685cbecaeb1e13 662 SMART SM01080 40 374 1.2E-50 T 22-04-2016 IPR007890 CHASE2 HRM2_RS02520 d07c729753c477e7a3ae56716af1c076 365 Gene3D G3DSA:2.40.50.140 299 346 1.4E-11 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS02520 d07c729753c477e7a3ae56716af1c076 365 PANTHER PTHR24220:SF151 303 346 1.3E-158 T 22-04-2016 HRM2_RS02520 d07c729753c477e7a3ae56716af1c076 365 PANTHER PTHR24220:SF151 5 273 1.3E-158 T 22-04-2016 HRM2_RS02520 d07c729753c477e7a3ae56716af1c076 365 SMART SM00382 28 211 5.0E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS02520 d07c729753c477e7a3ae56716af1c076 365 Pfam PF00005 ABC transporter 20 161 2.0E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS02520 d07c729753c477e7a3ae56716af1c076 365 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS02520 d07c729753c477e7a3ae56716af1c076 365 Gene3D G3DSA:2.40.50.100 350 364 4.8E-8 T 22-04-2016 HRM2_RS02520 d07c729753c477e7a3ae56716af1c076 365 Gene3D G3DSA:2.40.50.100 239 287 4.8E-8 T 22-04-2016 HRM2_RS02520 d07c729753c477e7a3ae56716af1c076 365 SUPERFAMILY SSF50331 236 364 1.24E-26 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal HRM2_RS02520 d07c729753c477e7a3ae56716af1c076 365 PANTHER PTHR24220 303 346 1.3E-158 T 22-04-2016 HRM2_RS02520 d07c729753c477e7a3ae56716af1c076 365 PANTHER PTHR24220 5 273 1.3E-158 T 22-04-2016 HRM2_RS02520 d07c729753c477e7a3ae56716af1c076 365 Gene3D G3DSA:3.40.50.300 3 234 2.4E-77 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02520 d07c729753c477e7a3ae56716af1c076 365 SUPERFAMILY SSF52540 4 243 7.91E-86 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02025 0c4dce40a35aaec926b5428e3aa68c33 411 PANTHER PTHR11228 1 266 6.0E-89 T 22-04-2016 HRM2_RS02025 0c4dce40a35aaec926b5428e3aa68c33 411 SUPERFAMILY SSF53146 300 400 4.71E-22 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS02025 0c4dce40a35aaec926b5428e3aa68c33 411 PANTHER PTHR11228:SF18 1 266 6.0E-89 T 22-04-2016 HRM2_RS02025 0c4dce40a35aaec926b5428e3aa68c33 411 Pfam PF04055 Radical SAM superfamily 25 206 4.5E-25 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS02025 0c4dce40a35aaec926b5428e3aa68c33 411 SMART SM00729 20 246 7.0E-4 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS02025 0c4dce40a35aaec926b5428e3aa68c33 411 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 26 37 - T 22-04-2016 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 HRM2_RS02025 0c4dce40a35aaec926b5428e3aa68c33 411 Gene3D G3DSA:3.30.420.130 299 399 9.7E-23 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS02025 0c4dce40a35aaec926b5428e3aa68c33 411 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 309 397 4.9E-13 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS02025 0c4dce40a35aaec926b5428e3aa68c33 411 SUPERFAMILY SSF102114 16 254 2.22E-38 T 22-04-2016 HRM2_RS02025 0c4dce40a35aaec926b5428e3aa68c33 411 Gene3D G3DSA:3.20.20.70 14 276 1.3E-41 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS17780 05b8d91801daa0a0ecbf92fca73ba202 340 Gene3D G3DSA:3.30.1360.10 182 234 2.9E-6 T 22-04-2016 HRM2_RS17780 05b8d91801daa0a0ecbf92fca73ba202 340 Gene3D G3DSA:1.10.150.20 254 331 2.6E-31 T 22-04-2016 HRM2_RS17780 05b8d91801daa0a0ecbf92fca73ba202 340 PANTHER PTHR32108 5 337 1.1E-125 T 22-04-2016 HRM2_RS17780 05b8d91801daa0a0ecbf92fca73ba202 340 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 264 328 4.0E-21 T 22-04-2016 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HRM2_RS17780 05b8d91801daa0a0ecbf92fca73ba202 340 SMART SM00662 28 236 2.7E-75 T 22-04-2016 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS17780 05b8d91801daa0a0ecbf92fca73ba202 340 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 34 230 2.4E-24 T 22-04-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HRM2_RS17780 05b8d91801daa0a0ecbf92fca73ba202 340 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 28 324 1.9E-109 T 22-04-2016 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HRM2_RS17780 05b8d91801daa0a0ecbf92fca73ba202 340 SUPERFAMILY SSF47789 257 330 1.83E-24 T 22-04-2016 HRM2_RS17780 05b8d91801daa0a0ecbf92fca73ba202 340 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 257 315 4.9E-24 T 22-04-2016 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HRM2_RS17780 05b8d91801daa0a0ecbf92fca73ba202 340 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 70 160 4.2E-18 T 22-04-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS17780 05b8d91801daa0a0ecbf92fca73ba202 340 SUPERFAMILY SSF55257 181 235 1.28E-28 T 22-04-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HRM2_RS17780 05b8d91801daa0a0ecbf92fca73ba202 340 SUPERFAMILY SSF55257 17 58 1.28E-28 T 22-04-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HRM2_RS17780 05b8d91801daa0a0ecbf92fca73ba202 340 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 11 324 34.474 T 22-04-2016 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HRM2_RS17780 05b8d91801daa0a0ecbf92fca73ba202 340 Gene3D G3DSA:3.30.1360.10 14 71 1.4E-11 T 22-04-2016 HRM2_RS17780 05b8d91801daa0a0ecbf92fca73ba202 340 PANTHER PTHR32108:SF0 5 337 1.1E-125 T 22-04-2016 HRM2_RS17780 05b8d91801daa0a0ecbf92fca73ba202 340 SUPERFAMILY SSF56553 58 180 5.23E-36 T 22-04-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS17780 05b8d91801daa0a0ecbf92fca73ba202 340 Gene3D G3DSA:2.170.120.12 72 179 1.1E-36 T 22-04-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS18650 27e3c41a2f1587f73cb3476faaec3981 601 SUPERFAMILY SSF52540 5 212 1.07E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18650 27e3c41a2f1587f73cb3476faaec3981 601 Gene3D G3DSA:3.30.70.240 407 484 8.0E-25 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain HRM2_RS18650 27e3c41a2f1587f73cb3476faaec3981 601 SUPERFAMILY SSF54980 307 392 1.15E-11 T 22-04-2016 IPR009022 Elongation factor G, III-V domain HRM2_RS18650 27e3c41a2f1587f73cb3476faaec3981 601 SUPERFAMILY SSF54980 404 516 1.44E-23 T 22-04-2016 IPR009022 Elongation factor G, III-V domain HRM2_RS18650 27e3c41a2f1587f73cb3476faaec3981 601 Gene3D G3DSA:3.30.70.870 309 406 5.7E-28 T 22-04-2016 HRM2_RS18650 27e3c41a2f1587f73cb3476faaec3981 601 Pfam PF00009 Elongation factor Tu GTP binding domain 8 200 4.9E-56 T 22-04-2016 HRM2_RS18650 27e3c41a2f1587f73cb3476faaec3981 601 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 145 3.3E-23 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HRM2_RS18650 27e3c41a2f1587f73cb3476faaec3981 601 Gene3D G3DSA:3.40.50.300 2 210 2.2E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18650 27e3c41a2f1587f73cb3476faaec3981 601 SUPERFAMILY SSF50447 156 305 2.05E-26 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain HRM2_RS18650 27e3c41a2f1587f73cb3476faaec3981 601 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 49 64 - T 22-04-2016 IPR031157 Tr-type G domain, conserved site HRM2_RS18650 27e3c41a2f1587f73cb3476faaec3981 601 PANTHER PTHR23115:SF14 1 597 1.2E-242 T 22-04-2016 IPR006298 GTP-binding protein TypA GO:0005525 HRM2_RS18650 27e3c41a2f1587f73cb3476faaec3981 601 Gene3D G3DSA:2.40.30.10 211 308 1.1E-22 T 22-04-2016 HRM2_RS18650 27e3c41a2f1587f73cb3476faaec3981 601 Gene3D G3DSA:2.40.50.250 487 581 1.2E-38 T 22-04-2016 HRM2_RS18650 27e3c41a2f1587f73cb3476faaec3981 601 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 10 601 1.1E-261 T 22-04-2016 IPR006298 GTP-binding protein TypA GO:0005525 HRM2_RS18650 27e3c41a2f1587f73cb3476faaec3981 601 PANTHER PTHR23115 1 597 1.2E-242 T 22-04-2016 HRM2_RS18650 27e3c41a2f1587f73cb3476faaec3981 601 Pfam PF00679 Elongation factor G C-terminus 402 484 3.5E-18 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain HRM2_RS18650 27e3c41a2f1587f73cb3476faaec3981 601 PRINTS PR00315 GTP-binding elongation factor signature 92 103 5.6E-17 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS18650 27e3c41a2f1587f73cb3476faaec3981 601 PRINTS PR00315 GTP-binding elongation factor signature 12 25 5.6E-17 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS18650 27e3c41a2f1587f73cb3476faaec3981 601 PRINTS PR00315 GTP-binding elongation factor signature 56 64 5.6E-17 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS18650 27e3c41a2f1587f73cb3476faaec3981 601 PRINTS PR00315 GTP-binding elongation factor signature 76 86 5.6E-17 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS18650 27e3c41a2f1587f73cb3476faaec3981 601 PRINTS PR00315 GTP-binding elongation factor signature 128 137 5.6E-17 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS22005 03213d80b0ae3e6e6c4dbac1edb4690c 95 PANTHER PTHR36455:SF1 2 95 7.0E-32 T 22-04-2016 HRM2_RS22005 03213d80b0ae3e6e6c4dbac1edb4690c 95 Pfam PF05717 IS66 Orf2 like protein 9 95 3.3E-37 T 22-04-2016 IPR008878 Transposase IS66, Orf2 HRM2_RS22005 03213d80b0ae3e6e6c4dbac1edb4690c 95 PANTHER PTHR36455 2 95 7.0E-32 T 22-04-2016 HRM2_RS23275 705eb84acec97ed3ad525677e4afabc0 464 SUPERFAMILY SSF55920 168 457 1.83E-53 T 22-04-2016 IPR000994 Peptidase M24, structural domain HRM2_RS23275 705eb84acec97ed3ad525677e4afabc0 464 Pfam PF00557 Metallopeptidase family M24 174 438 4.3E-41 T 22-04-2016 IPR000994 Peptidase M24, structural domain HRM2_RS23275 705eb84acec97ed3ad525677e4afabc0 464 PANTHER PTHR10804 372 460 9.8E-105 T 22-04-2016 HRM2_RS23275 705eb84acec97ed3ad525677e4afabc0 464 PANTHER PTHR10804 7 356 9.8E-105 T 22-04-2016 HRM2_RS23275 705eb84acec97ed3ad525677e4afabc0 464 SUPERFAMILY SSF53092 2 167 1.46E-28 T 22-04-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal HRM2_RS23275 705eb84acec97ed3ad525677e4afabc0 464 Pfam PF05195 Aminopeptidase P, N-terminal domain 7 117 8.0E-20 T 22-04-2016 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 HRM2_RS23275 705eb84acec97ed3ad525677e4afabc0 464 Gene3D G3DSA:3.90.230.10 171 454 3.0E-57 T 22-04-2016 IPR000994 Peptidase M24, structural domain HRM2_RS23275 705eb84acec97ed3ad525677e4afabc0 464 Gene3D G3DSA:3.40.350.10 2 170 2.8E-26 T 22-04-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal HRM2_RS23275 705eb84acec97ed3ad525677e4afabc0 464 SMART SM01011 2 134 2.2E-22 T 22-04-2016 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 HRM2_RS23275 705eb84acec97ed3ad525677e4afabc0 464 PANTHER PTHR10804:SF17 372 460 9.8E-105 T 22-04-2016 HRM2_RS23275 705eb84acec97ed3ad525677e4afabc0 464 PANTHER PTHR10804:SF17 7 356 9.8E-105 T 22-04-2016 HRM2_RS16820 fda8750ea8941b71213daff4611b8374 228 PANTHER PTHR30055:SF73 10 70 1.6E-14 T 22-04-2016 HRM2_RS16820 fda8750ea8941b71213daff4611b8374 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 2.1E-5 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS16820 fda8750ea8941b71213daff4611b8374 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 2.1E-5 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS16820 fda8750ea8941b71213daff4611b8374 228 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 56 - T 22-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site HRM2_RS16820 fda8750ea8941b71213daff4611b8374 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 8.0E-12 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS16820 fda8750ea8941b71213daff4611b8374 228 SUPERFAMILY SSF46689 6 70 6.67E-15 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS16820 fda8750ea8941b71213daff4611b8374 228 Gene3D G3DSA:1.10.357.10 7 203 7.1E-32 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HRM2_RS16820 fda8750ea8941b71213daff4611b8374 228 PANTHER PTHR30055 10 70 1.6E-14 T 22-04-2016 HRM2_RS16820 fda8750ea8941b71213daff4611b8374 228 Pfam PF09209 Domain of unknown function (DUF1956) 93 210 4.1E-5 T 22-04-2016 IPR015292 Transcription regulator YbiH, C-terminal HRM2_RS04245 efaad07606a734ec76ae65432e7670cb 308 Gene3D G3DSA:2.20.150.10 9 35 6.5E-6 T 22-04-2016 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain KEGG: 00052+2.7.1.144|KEGG: 00710+2.7.1.14|MetaCyc: PWY-7077|MetaCyc: PWY-7395|UniPathway: UPA00704 HRM2_RS04245 efaad07606a734ec76ae65432e7670cb 308 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 246 259 - T 22-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 HRM2_RS04245 efaad07606a734ec76ae65432e7670cb 308 PANTHER PTHR10584 1 308 9.9E-83 T 22-04-2016 HRM2_RS04245 efaad07606a734ec76ae65432e7670cb 308 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 305 3.6E-101 T 22-04-2016 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 HRM2_RS04245 efaad07606a734ec76ae65432e7670cb 308 SUPERFAMILY SSF53613 1 291 1.87E-69 T 22-04-2016 IPR029056 Ribokinase-like HRM2_RS04245 efaad07606a734ec76ae65432e7670cb 308 Gene3D G3DSA:3.40.1190.20 36 306 6.0E-82 T 22-04-2016 IPR029056 Ribokinase-like HRM2_RS04245 efaad07606a734ec76ae65432e7670cb 308 PIRSF PIRSF000535 1 308 2.4E-86 T 22-04-2016 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 HRM2_RS04245 efaad07606a734ec76ae65432e7670cb 308 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 305 2.0E-98 T 22-04-2016 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 HRM2_RS04245 efaad07606a734ec76ae65432e7670cb 308 Pfam PF00294 pfkB family carbohydrate kinase 11 290 6.9E-50 T 22-04-2016 IPR011611 Carbohydrate kinase PfkB HRM2_RS04245 efaad07606a734ec76ae65432e7670cb 308 PANTHER PTHR10584:SF170 1 308 9.9E-83 T 22-04-2016 HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 307 430 3.8E-15 T 22-04-2016 IPR000014 PAS domain HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 Pfam PF13426 PAS domain 328 421 1.3E-9 T 22-04-2016 IPR000014 PAS domain HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 SUPERFAMILY SSF52172 806 923 1.34E-28 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 SMART SM00091 310 374 8.7E-4 T 22-04-2016 IPR000014 PAS domain HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 SMART SM00091 435 505 10.0 T 22-04-2016 IPR000014 PAS domain HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 Gene3D G3DSA:3.30.565.10 608 785 8.3E-37 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 Pfam PF00512 His Kinase A (phospho-acceptor) domain 560 620 4.9E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 SMART SM00062 26 245 7.5E-38 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 662 782 4.9E-19 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 SMART SM00387 662 785 7.9E-30 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 Gene3D G3DSA:3.40.190.10 103 203 3.6E-14 T 22-04-2016 HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 SUPERFAMILY SSF55874 612 783 3.41E-35 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 Pfam PF13188 PAS domain 436 489 0.0011 T 22-04-2016 IPR000014 PAS domain HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 SUPERFAMILY SSF55785 297 421 3.14E-18 T 22-04-2016 IPR000014 PAS domain HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 SMART SM00448 806 919 2.5E-24 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 PRINTS PR00344 Bacterial sensor protein C-terminal signature 769 782 1.5E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 PRINTS PR00344 Bacterial sensor protein C-terminal signature 714 728 1.5E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 PRINTS PR00344 Bacterial sensor protein C-terminal signature 745 763 1.5E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 PRINTS PR00344 Bacterial sensor protein C-terminal signature 732 742 1.5E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 SUPERFAMILY SSF47384 545 622 7.46E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 27 243 7.7E-49 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 PANTHER PTHR24423 286 923 1.7E-121 T 22-04-2016 HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 SUPERFAMILY SSF53850 27 244 3.63E-53 T 22-04-2016 HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 Gene3D G3DSA:3.30.450.20 297 420 3.8E-18 T 22-04-2016 HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 Pfam PF00072 Response regulator receiver domain 808 918 2.6E-21 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 Gene3D G3DSA:3.40.50.2300 805 924 8.1E-29 T 22-04-2016 HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 Gene3D G3DSA:3.30.450.20 421 538 5.0E-12 T 22-04-2016 HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 Gene3D G3DSA:1.10.287.130 550 607 4.8E-5 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 SUPERFAMILY SSF55785 419 530 4.36E-13 T 22-04-2016 IPR000014 PAS domain HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 SMART SM00388 556 622 2.1E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 Gene3D G3DSA:3.40.190.10 204 243 1.1E-28 T 22-04-2016 HRM2_RS25405 878581643a3afaebaf5d9cb95c72c3d5 926 Gene3D G3DSA:3.40.190.10 27 102 1.1E-28 T 22-04-2016 HRM2_RS01205 1c1c414ba48812b0d0a34cf2479683c6 271 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 19 268 5.2E-80 T 22-04-2016 IPR011862 Phosphate binding protein GO:0006810 HRM2_RS01205 1c1c414ba48812b0d0a34cf2479683c6 271 SUPERFAMILY SSF53850 27 270 4.21E-75 T 22-04-2016 HRM2_RS01205 1c1c414ba48812b0d0a34cf2479683c6 271 Pfam PF12849 PBP superfamily domain 25 256 1.3E-39 T 22-04-2016 IPR024370 PBP domain HRM2_RS01205 1c1c414ba48812b0d0a34cf2479683c6 271 Gene3D G3DSA:3.40.190.10 113 229 9.7E-42 T 22-04-2016 HRM2_RS01205 1c1c414ba48812b0d0a34cf2479683c6 271 PANTHER PTHR30570:SF1 25 271 7.6E-70 T 22-04-2016 HRM2_RS01205 1c1c414ba48812b0d0a34cf2479683c6 271 PANTHER PTHR30570 25 271 7.6E-70 T 22-04-2016 HRM2_RS01205 1c1c414ba48812b0d0a34cf2479683c6 271 Gene3D G3DSA:3.40.190.10 230 267 1.0E-4 T 22-04-2016 HRM2_RS01205 1c1c414ba48812b0d0a34cf2479683c6 271 Gene3D G3DSA:3.40.190.10 40 112 1.0E-4 T 22-04-2016 HRM2_RS07260 94455d404d42bec42f3218a6ca4c4fc4 468 PANTHER PTHR30365 1 456 9.0E-236 T 22-04-2016 HRM2_RS07260 94455d404d42bec42f3218a6ca4c4fc4 468 PANTHER PTHR30365:SF8 1 456 9.0E-236 T 22-04-2016 HRM2_RS07260 94455d404d42bec42f3218a6ca4c4fc4 468 PIRSF PIRSF006446 3 457 4.6E-190 T 22-04-2016 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 HRM2_RS07260 94455d404d42bec42f3218a6ca4c4fc4 468 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 10 437 1.7E-159 T 22-04-2016 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 HRM2_RS10580 89e098fcafeb0b8acf39612aeca565f3 368 Gene3D G3DSA:3.30.70.20 274 338 6.5E-15 T 22-04-2016 HRM2_RS10580 89e098fcafeb0b8acf39612aeca565f3 368 Pfam PF14697 4Fe-4S dicluster domain 274 334 4.0E-9 T 22-04-2016 HRM2_RS10580 89e098fcafeb0b8acf39612aeca565f3 368 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 317 328 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS10580 89e098fcafeb0b8acf39612aeca565f3 368 SUPERFAMILY SSF54862 269 339 9.26E-16 T 22-04-2016 HRM2_RS10370 13fb09b8b137a8c016af0f206478728e 164 PANTHER PTHR31964 1 145 1.6E-20 T 22-04-2016 HRM2_RS10370 13fb09b8b137a8c016af0f206478728e 164 SUPERFAMILY SSF52402 4 150 1.93E-27 T 22-04-2016 HRM2_RS10370 13fb09b8b137a8c016af0f206478728e 164 PRINTS PR01438 Universal stress protein signature 127 149 5.2E-8 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS10370 13fb09b8b137a8c016af0f206478728e 164 PRINTS PR01438 Universal stress protein signature 109 121 5.2E-8 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS10370 13fb09b8b137a8c016af0f206478728e 164 PRINTS PR01438 Universal stress protein signature 4 22 5.2E-8 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS10370 13fb09b8b137a8c016af0f206478728e 164 PANTHER PTHR31964:SF45 1 145 1.6E-20 T 22-04-2016 HRM2_RS10370 13fb09b8b137a8c016af0f206478728e 164 Pfam PF00582 Universal stress protein family 5 145 8.0E-19 T 22-04-2016 IPR006016 UspA GO:0006950 HRM2_RS10370 13fb09b8b137a8c016af0f206478728e 164 Gene3D G3DSA:3.40.50.620 3 149 7.5E-27 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS18955 6654652f44613b7886b0974c3d1f3105 110 Pfam PF01230 HIT domain 13 107 5.5E-26 T 22-04-2016 IPR001310 Histidine triad (HIT) protein HRM2_RS18955 6654652f44613b7886b0974c3d1f3105 110 PANTHER PTHR23089:SF2 3 109 1.1E-39 T 22-04-2016 HRM2_RS18955 6654652f44613b7886b0974c3d1f3105 110 Gene3D G3DSA:3.30.428.10 2 109 6.3E-36 T 22-04-2016 IPR011146 HIT-like domain GO:0003824 HRM2_RS18955 6654652f44613b7886b0974c3d1f3105 110 PANTHER PTHR23089 3 109 1.1E-39 T 22-04-2016 IPR001310 Histidine triad (HIT) protein HRM2_RS18955 6654652f44613b7886b0974c3d1f3105 110 PRINTS PR00332 Histidine triad family signature 6 22 7.8E-18 T 22-04-2016 IPR001310 Histidine triad (HIT) protein HRM2_RS18955 6654652f44613b7886b0974c3d1f3105 110 PRINTS PR00332 Histidine triad family signature 95 105 7.8E-18 T 22-04-2016 IPR001310 Histidine triad (HIT) protein HRM2_RS18955 6654652f44613b7886b0974c3d1f3105 110 PRINTS PR00332 Histidine triad family signature 27 45 7.8E-18 T 22-04-2016 IPR001310 Histidine triad (HIT) protein HRM2_RS18955 6654652f44613b7886b0974c3d1f3105 110 ProSitePatterns PS00892 HIT domain signature. 88 106 - T 22-04-2016 IPR019808 Histidine triad, conserved site HRM2_RS18955 6654652f44613b7886b0974c3d1f3105 110 SUPERFAMILY SSF54197 1 109 8.51E-37 T 22-04-2016 IPR011146 HIT-like domain GO:0003824 HRM2_RS08895 37be7a6e8a8164157326c9a73e34f63c 306 PANTHER PTHR10256 1 294 2.9E-93 T 22-04-2016 HRM2_RS08895 37be7a6e8a8164157326c9a73e34f63c 306 Pfam PF00586 AIR synthase related protein, N-terminal domain 7 114 2.7E-17 T 22-04-2016 IPR016188 PurM-like, N-terminal domain HRM2_RS08895 37be7a6e8a8164157326c9a73e34f63c 306 Pfam PF02769 AIR synthase related protein, C-terminal domain 128 298 9.3E-26 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain HRM2_RS08895 37be7a6e8a8164157326c9a73e34f63c 306 SUPERFAMILY SSF56042 120 298 1.38E-49 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain HRM2_RS08895 37be7a6e8a8164157326c9a73e34f63c 306 TIGRFAM TIGR00476 selD: selenide, water dikinase 1 271 1.1E-102 T 22-04-2016 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 HRM2_RS08895 37be7a6e8a8164157326c9a73e34f63c 306 Gene3D G3DSA:3.30.1330.10 4 119 8.6E-25 T 22-04-2016 IPR016188 PurM-like, N-terminal domain HRM2_RS08895 37be7a6e8a8164157326c9a73e34f63c 306 Gene3D G3DSA:3.90.650.10 132 298 3.2E-15 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain HRM2_RS08895 37be7a6e8a8164157326c9a73e34f63c 306 PIRSF PIRSF036407 1 306 1.7E-103 T 22-04-2016 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 HRM2_RS08895 37be7a6e8a8164157326c9a73e34f63c 306 SUPERFAMILY SSF55326 3 118 6.8E-34 T 22-04-2016 HRM2_RS10310 37a106ffe1d67554a67931488e363290 530 PANTHER PTHR13370:SF4 225 510 5.2E-41 T 22-04-2016 HRM2_RS10310 37a106ffe1d67554a67931488e363290 530 Gene3D G3DSA:3.40.50.150 225 480 1.3E-48 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS10310 37a106ffe1d67554a67931488e363290 530 Pfam PF01555 DNA methylase 242 469 5.8E-41 T 22-04-2016 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 HRM2_RS10310 37a106ffe1d67554a67931488e363290 530 SMART SM00470 10 99 1.1E-9 T 22-04-2016 IPR003115 ParB/Sulfiredoxin HRM2_RS10310 37a106ffe1d67554a67931488e363290 530 SUPERFAMILY SSF53335 228 474 3.73E-44 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS10310 37a106ffe1d67554a67931488e363290 530 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 412 429 4.1E-23 T 22-04-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HRM2_RS10310 37a106ffe1d67554a67931488e363290 530 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 431 449 4.1E-23 T 22-04-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HRM2_RS10310 37a106ffe1d67554a67931488e363290 530 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 272 292 4.1E-23 T 22-04-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HRM2_RS10310 37a106ffe1d67554a67931488e363290 530 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 454 474 4.1E-23 T 22-04-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HRM2_RS10310 37a106ffe1d67554a67931488e363290 530 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 240 254 4.1E-23 T 22-04-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HRM2_RS10310 37a106ffe1d67554a67931488e363290 530 SUPERFAMILY SSF109709 94 201 3.01E-15 T 22-04-2016 HRM2_RS10310 37a106ffe1d67554a67931488e363290 530 Gene3D G3DSA:3.90.1530.10 7 105 1.9E-18 T 22-04-2016 HRM2_RS10310 37a106ffe1d67554a67931488e363290 530 SUPERFAMILY SSF110849 9 123 9.94E-18 T 22-04-2016 IPR003115 ParB/Sulfiredoxin HRM2_RS10310 37a106ffe1d67554a67931488e363290 530 PANTHER PTHR13370 225 510 5.2E-41 T 22-04-2016 HRM2_RS10310 37a106ffe1d67554a67931488e363290 530 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 9 176 2.4E-21 T 22-04-2016 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 HRM2_RS10310 37a106ffe1d67554a67931488e363290 530 Pfam PF02195 ParB-like nuclease domain 11 89 1.2E-11 T 22-04-2016 IPR003115 ParB/Sulfiredoxin HRM2_RS10310 37a106ffe1d67554a67931488e363290 530 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 245 250 - T 22-04-2016 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 KEGG: 00860+2.1.1.11|MetaCyc: PWY-5531|MetaCyc: PWY-7159 HRM2_RS05665 1a15e27a23e60a2a97301781b0097085 293 Pfam PF02687 FtsX-like permease family 174 289 1.9E-12 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 HRM2_RS05665 1a15e27a23e60a2a97301781b0097085 293 PIRSF PIRSF003097 1 293 6.3E-81 T 22-04-2016 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 HRM2_RS05665 1a15e27a23e60a2a97301781b0097085 293 PANTHER PTHR30489 17 292 1.3E-22 T 22-04-2016 HRM2_RS15210 a99d7b202871337d7eacb2143b142138 132 SUPERFAMILY SSF52172 4 130 1.32E-33 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS15210 a99d7b202871337d7eacb2143b142138 132 Pfam PF00072 Response regulator receiver domain 7 127 7.8E-22 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS15210 a99d7b202871337d7eacb2143b142138 132 Gene3D G3DSA:3.40.50.2300 3 130 1.3E-36 T 22-04-2016 HRM2_RS15210 a99d7b202871337d7eacb2143b142138 132 SMART SM00448 5 127 3.1E-30 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS15210 a99d7b202871337d7eacb2143b142138 132 PANTHER PTHR26402 5 130 1.1E-33 T 22-04-2016 HRM2_RS01480 9a24e1a2b79aaa306a5d68e9a08a327c 402 PANTHER PTHR10909 1 402 6.1E-140 T 22-04-2016 HRM2_RS01480 9a24e1a2b79aaa306a5d68e9a08a327c 402 Gene3D G3DSA:1.10.540.10 1 126 4.5E-25 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS01480 9a24e1a2b79aaa306a5d68e9a08a327c 402 SUPERFAMILY SSF56645 1 253 1.7E-65 T 22-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 HRM2_RS01480 9a24e1a2b79aaa306a5d68e9a08a327c 402 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 216 1.0E-16 T 22-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 HRM2_RS01480 9a24e1a2b79aaa306a5d68e9a08a327c 402 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 240 393 1.5E-34 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS01480 9a24e1a2b79aaa306a5d68e9a08a327c 402 Gene3D G3DSA:2.40.110.10 127 229 8.5E-34 T 22-04-2016 HRM2_RS01480 9a24e1a2b79aaa306a5d68e9a08a327c 402 Gene3D G3DSA:1.20.140.10 230 397 3.1E-45 T 22-04-2016 HRM2_RS01480 9a24e1a2b79aaa306a5d68e9a08a327c 402 PANTHER PTHR10909:SF195 1 402 6.1E-140 T 22-04-2016 HRM2_RS01480 9a24e1a2b79aaa306a5d68e9a08a327c 402 SUPERFAMILY SSF47203 239 397 3.38E-43 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS01480 9a24e1a2b79aaa306a5d68e9a08a327c 402 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 124 2.4E-16 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS19885 0c33b6919d3ba3f64c9d7539ba440f7a 120 SMART SM00448 1 111 1.3E-17 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS19885 0c33b6919d3ba3f64c9d7539ba440f7a 120 SUPERFAMILY SSF52172 2 116 4.7E-29 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS19885 0c33b6919d3ba3f64c9d7539ba440f7a 120 Pfam PF00072 Response regulator receiver domain 3 109 1.2E-20 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS19885 0c33b6919d3ba3f64c9d7539ba440f7a 120 Gene3D G3DSA:3.40.50.2300 2 118 1.3E-29 T 22-04-2016 HRM2_RS19885 0c33b6919d3ba3f64c9d7539ba440f7a 120 PANTHER PTHR26402 1 108 4.9E-26 T 22-04-2016 HRM2_RS25525 60e75d97fa4c9e5c21e2e96be3774855 989 SUPERFAMILY SSF55874 668 843 1.28E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25525 60e75d97fa4c9e5c21e2e96be3774855 989 SMART SM00448 861 974 1.6E-18 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS25525 60e75d97fa4c9e5c21e2e96be3774855 989 Gene3D G3DSA:3.30.450.20 478 588 6.3E-12 T 22-04-2016 HRM2_RS25525 60e75d97fa4c9e5c21e2e96be3774855 989 SUPERFAMILY SSF55785 476 595 4.19E-12 T 22-04-2016 IPR000014 PAS domain HRM2_RS25525 60e75d97fa4c9e5c21e2e96be3774855 989 SMART SM00387 719 842 3.7E-28 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25525 60e75d97fa4c9e5c21e2e96be3774855 989 PANTHER PTHR24423 475 982 1.0E-131 T 22-04-2016 HRM2_RS25525 60e75d97fa4c9e5c21e2e96be3774855 989 SMART SM00388 612 678 1.2E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25525 60e75d97fa4c9e5c21e2e96be3774855 989 PANTHER PTHR24423:SF544 475 982 1.0E-131 T 22-04-2016 HRM2_RS25525 60e75d97fa4c9e5c21e2e96be3774855 989 Gene3D G3DSA:1.10.287.130 608 663 1.8E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25525 60e75d97fa4c9e5c21e2e96be3774855 989 Pfam PF00072 Response regulator receiver domain 863 974 4.6E-18 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS25525 60e75d97fa4c9e5c21e2e96be3774855 989 SUPERFAMILY SSF47384 606 679 6.28E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25525 60e75d97fa4c9e5c21e2e96be3774855 989 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 720 840 1.3E-19 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25525 60e75d97fa4c9e5c21e2e96be3774855 989 SUPERFAMILY SSF52172 862 985 2.7E-27 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS25525 60e75d97fa4c9e5c21e2e96be3774855 989 SUPERFAMILY SSF55785 334 400 3.05E-8 T 22-04-2016 IPR000014 PAS domain HRM2_RS25525 60e75d97fa4c9e5c21e2e96be3774855 989 Pfam PF00512 His Kinase A (phospho-acceptor) domain 614 677 5.6E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25525 60e75d97fa4c9e5c21e2e96be3774855 989 Pfam PF13188 PAS domain 352 402 0.013 T 22-04-2016 IPR000014 PAS domain HRM2_RS25525 60e75d97fa4c9e5c21e2e96be3774855 989 Pfam PF13188 PAS domain 491 543 0.033 T 22-04-2016 IPR000014 PAS domain HRM2_RS25525 60e75d97fa4c9e5c21e2e96be3774855 989 Pfam PF04392 ABC transporter substrate binding protein 63 287 1.0E-10 T 22-04-2016 IPR007487 ABC transporter, substrate-binding protein HRM2_RS25525 60e75d97fa4c9e5c21e2e96be3774855 989 Gene3D G3DSA:3.40.50.2300 860 985 2.1E-27 T 22-04-2016 HRM2_RS25525 60e75d97fa4c9e5c21e2e96be3774855 989 Gene3D G3DSA:3.30.565.10 664 841 2.5E-39 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25525 60e75d97fa4c9e5c21e2e96be3774855 989 Gene3D G3DSA:3.30.450.20 341 477 4.2E-9 T 22-04-2016 HRM2_RS25525 60e75d97fa4c9e5c21e2e96be3774855 989 PRINTS PR00344 Bacterial sensor protein C-terminal signature 789 799 4.4E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25525 60e75d97fa4c9e5c21e2e96be3774855 989 PRINTS PR00344 Bacterial sensor protein C-terminal signature 771 785 4.4E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25525 60e75d97fa4c9e5c21e2e96be3774855 989 PRINTS PR00344 Bacterial sensor protein C-terminal signature 826 839 4.4E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25525 60e75d97fa4c9e5c21e2e96be3774855 989 PRINTS PR00344 Bacterial sensor protein C-terminal signature 802 820 4.4E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS03080 f2e3068a005ea1ed9689b82642540a4a 358 PANTHER PTHR32196:SF30 2 347 5.4E-65 T 22-04-2016 HRM2_RS03080 f2e3068a005ea1ed9689b82642540a4a 358 PANTHER PTHR32196 2 347 5.4E-65 T 22-04-2016 HRM2_RS03080 f2e3068a005ea1ed9689b82642540a4a 358 Pfam PF02653 Branched-chain amino acid transport system / permease component 63 341 2.7E-43 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 HRM2_RS03240 78f6c2d699985d118eb9802985d96dd4 117 Gene3D G3DSA:3.30.230.10 4 112 2.1E-32 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HRM2_RS03240 78f6c2d699985d118eb9802985d96dd4 117 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 13 105 3.0E-12 T 22-04-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 HRM2_RS03240 78f6c2d699985d118eb9802985d96dd4 117 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 55 69 - T 22-04-2016 IPR020539 Ribonuclease P, conserved site GO:0004526 HRM2_RS03240 78f6c2d699985d118eb9802985d96dd4 117 PANTHER PTHR33992 2 114 3.4E-32 T 22-04-2016 HRM2_RS03240 78f6c2d699985d118eb9802985d96dd4 117 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 9 114 5.4E-20 T 22-04-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 HRM2_RS03240 78f6c2d699985d118eb9802985d96dd4 117 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 6 115 17.499 T 22-04-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 HRM2_RS03240 78f6c2d699985d118eb9802985d96dd4 117 Pfam PF00825 Ribonuclease P 6 112 9.8E-29 T 22-04-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 HRM2_RS03240 78f6c2d699985d118eb9802985d96dd4 117 SUPERFAMILY SSF54211 4 114 8.09E-28 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS12995 db8eed80a5eb9208baa91d0f310acae4 1115 SUPERFAMILY SSF48452 769 938 1.03E-17 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS12995 db8eed80a5eb9208baa91d0f310acae4 1115 Gene3D G3DSA:3.30.70.1230 1 182 7.8E-41 T 22-04-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 HRM2_RS12995 db8eed80a5eb9208baa91d0f310acae4 1115 SUPERFAMILY SSF55073 1 178 2.04E-44 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS12995 db8eed80a5eb9208baa91d0f310acae4 1115 PANTHER PTHR16305 1 673 5.3E-107 T 22-04-2016 HRM2_RS12995 db8eed80a5eb9208baa91d0f310acae4 1115 PANTHER PTHR16305:SF28 1 673 5.3E-107 T 22-04-2016 HRM2_RS12995 db8eed80a5eb9208baa91d0f310acae4 1115 SMART SM00028 666 699 0.35 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS12995 db8eed80a5eb9208baa91d0f310acae4 1115 SMART SM00028 943 976 210.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS12995 db8eed80a5eb9208baa91d0f310acae4 1115 SMART SM00028 1032 1065 37.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS12995 db8eed80a5eb9208baa91d0f310acae4 1115 SMART SM00028 823 856 2.5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS12995 db8eed80a5eb9208baa91d0f310acae4 1115 Pfam PF13191 AAA ATPase domain 195 385 1.0E-25 T 22-04-2016 HRM2_RS12995 db8eed80a5eb9208baa91d0f310acae4 1115 Gene3D G3DSA:1.25.40.10 609 693 4.4E-23 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS12995 db8eed80a5eb9208baa91d0f310acae4 1115 Gene3D G3DSA:1.25.40.10 811 972 4.4E-23 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS12995 db8eed80a5eb9208baa91d0f310acae4 1115 Gene3D G3DSA:3.40.50.300 189 291 2.0E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12995 db8eed80a5eb9208baa91d0f310acae4 1115 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 1 172 2.8E-31 T 22-04-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 HRM2_RS12995 db8eed80a5eb9208baa91d0f310acae4 1115 SMART SM00044 1 169 1.7E-5 T 22-04-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 HRM2_RS12995 db8eed80a5eb9208baa91d0f310acae4 1115 PANTHER PTHR16305:SF28 819 885 5.3E-107 T 22-04-2016 HRM2_RS12995 db8eed80a5eb9208baa91d0f310acae4 1115 SUPERFAMILY SSF48452 614 695 2.93E-5 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS12995 db8eed80a5eb9208baa91d0f310acae4 1115 PANTHER PTHR16305 819 885 5.3E-107 T 22-04-2016 HRM2_RS12995 db8eed80a5eb9208baa91d0f310acae4 1115 SUPERFAMILY SSF52540 184 304 2.32E-14 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12995 db8eed80a5eb9208baa91d0f310acae4 1115 SUPERFAMILY SSF52540 369 513 2.32E-14 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23630 6fe5c943f5f5655e2353458763c2c966 777 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 314 386 4.7E-9 T 22-04-2016 IPR028261 Dihydroprymidine dehydrogenase domain II HRM2_RS23630 6fe5c943f5f5655e2353458763c2c966 777 SUPERFAMILY SSF54862 719 773 2.65E-10 T 22-04-2016 HRM2_RS23630 6fe5c943f5f5655e2353458763c2c966 777 Gene3D G3DSA:1.10.1060.10 314 402 2.7E-17 T 22-04-2016 HRM2_RS23630 6fe5c943f5f5655e2353458763c2c966 777 Gene3D G3DSA:2.160.20.60 37 244 6.2E-34 T 22-04-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 HRM2_RS23630 6fe5c943f5f5655e2353458763c2c966 777 Gene3D G3DSA:3.30.70.20 717 771 1.3E-13 T 22-04-2016 HRM2_RS23630 6fe5c943f5f5655e2353458763c2c966 777 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 754 765 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS23630 6fe5c943f5f5655e2353458763c2c966 777 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 720 731 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS23630 6fe5c943f5f5655e2353458763c2c966 777 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 402 662 4.0E-31 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS23630 6fe5c943f5f5655e2353458763c2c966 777 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 638 656 9.1E-5 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HRM2_RS23630 6fe5c943f5f5655e2353458763c2c966 777 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 403 425 9.1E-5 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HRM2_RS23630 6fe5c943f5f5655e2353458763c2c966 777 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 525 549 9.1E-5 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HRM2_RS23630 6fe5c943f5f5655e2353458763c2c966 777 Pfam PF12838 4Fe-4S dicluster domain 719 768 4.6E-7 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS23630 6fe5c943f5f5655e2353458763c2c966 777 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 486 504 3.6E-21 T 22-04-2016 HRM2_RS23630 6fe5c943f5f5655e2353458763c2c966 777 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 603 619 3.6E-21 T 22-04-2016 HRM2_RS23630 6fe5c943f5f5655e2353458763c2c966 777 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 628 650 3.6E-21 T 22-04-2016 HRM2_RS23630 6fe5c943f5f5655e2353458763c2c966 777 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 404 423 3.6E-21 T 22-04-2016 HRM2_RS23630 6fe5c943f5f5655e2353458763c2c966 777 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 529 547 3.6E-21 T 22-04-2016 HRM2_RS23630 6fe5c943f5f5655e2353458763c2c966 777 Pfam PF01493 GXGXG motif 56 199 4.5E-11 T 22-04-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 HRM2_RS23630 6fe5c943f5f5655e2353458763c2c966 777 PANTHER PTHR11938:SF108 314 678 8.9E-31 T 22-04-2016 HRM2_RS23630 6fe5c943f5f5655e2353458763c2c966 777 Gene3D G3DSA:3.40.50.720 403 541 1.3E-33 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS23630 6fe5c943f5f5655e2353458763c2c966 777 Gene3D G3DSA:3.50.50.60 542 670 5.0E-24 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS23630 6fe5c943f5f5655e2353458763c2c966 777 SUPERFAMILY SSF69336 16 244 3.4E-38 T 22-04-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 HRM2_RS23630 6fe5c943f5f5655e2353458763c2c966 777 PANTHER PTHR11938 314 678 8.9E-31 T 22-04-2016 HRM2_RS23630 6fe5c943f5f5655e2353458763c2c966 777 SUPERFAMILY SSF51905 361 670 1.55E-41 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS03895 228860565babe1f412894586e2bbb535 378 SUPERFAMILY SSF53850 91 304 7.45E-19 T 22-04-2016 HRM2_RS03895 228860565babe1f412894586e2bbb535 378 PANTHER PTHR30024:SF1 91 322 2.1E-13 T 22-04-2016 HRM2_RS03895 228860565babe1f412894586e2bbb535 378 Pfam PF13379 NMT1-like family 34 311 2.1E-61 T 22-04-2016 HRM2_RS03895 228860565babe1f412894586e2bbb535 378 PANTHER PTHR30024 91 322 2.1E-13 T 22-04-2016 HRM2_RS03895 228860565babe1f412894586e2bbb535 378 Gene3D G3DSA:3.40.190.10 170 286 2.3E-7 T 22-04-2016 HRM2_RS07395 fbb0b75a2ea3f28aae5d1e9ae24d8106 249 Gene3D G3DSA:3.40.50.1820 1 247 1.3E-25 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS07395 fbb0b75a2ea3f28aae5d1e9ae24d8106 249 SUPERFAMILY SSF53474 3 245 8.97E-22 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS07395 fbb0b75a2ea3f28aae5d1e9ae24d8106 249 Pfam PF00756 Putative esterase 71 240 6.7E-12 T 22-04-2016 IPR000801 Putative esterase HRM2_RS00635 4eb71da9b21fa3c65e498af04a345a72 527 PANTHER PTHR10366:SF401 15 255 2.1E-85 T 22-04-2016 HRM2_RS00635 4eb71da9b21fa3c65e498af04a345a72 527 Pfam PF11066 Protein of unknown function (DUF2867) 346 488 5.3E-21 T 22-04-2016 IPR021295 Protein of unknown function DUF2867 HRM2_RS00635 4eb71da9b21fa3c65e498af04a345a72 527 Gene3D G3DSA:3.40.50.720 13 238 3.8E-36 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS00635 4eb71da9b21fa3c65e498af04a345a72 527 Pfam PF13460 NAD(P)H-binding 20 164 1.7E-15 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS00635 4eb71da9b21fa3c65e498af04a345a72 527 PANTHER PTHR10366 15 255 2.1E-85 T 22-04-2016 HRM2_RS00635 4eb71da9b21fa3c65e498af04a345a72 527 PANTHER PTHR10366 276 318 2.1E-85 T 22-04-2016 HRM2_RS00635 4eb71da9b21fa3c65e498af04a345a72 527 PANTHER PTHR10366:SF401 276 318 2.1E-85 T 22-04-2016 HRM2_RS00635 4eb71da9b21fa3c65e498af04a345a72 527 SUPERFAMILY SSF51735 14 311 2.2E-44 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS09270 7814eb758609c04d6b88b95f240f95b7 552 PANTHER PTHR10229:SF0 28 552 3.4E-176 T 22-04-2016 HRM2_RS09270 7814eb758609c04d6b88b95f240f95b7 552 PANTHER PTHR10229 28 552 3.4E-176 T 22-04-2016 IPR016496 GTPase HflX GO:0005525 HRM2_RS09270 7814eb758609c04d6b88b95f240f95b7 552 Pfam PF13167 GTP-binding GTPase N-terminal 214 301 2.8E-27 T 22-04-2016 IPR025121 GTPase HflX, N-terminal HRM2_RS09270 7814eb758609c04d6b88b95f240f95b7 552 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 387 515 1.2E-11 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HRM2_RS09270 7814eb758609c04d6b88b95f240f95b7 552 Hamap MF_00900 GTPase HflX [hflX]. 216 552 41.455 T 22-04-2016 IPR016496 GTPase HflX GO:0005525 HRM2_RS09270 7814eb758609c04d6b88b95f240f95b7 552 SUPERFAMILY SSF52540 386 546 9.5E-36 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09270 7814eb758609c04d6b88b95f240f95b7 552 Gene3D G3DSA:3.40.50.300 381 548 3.4E-30 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09270 7814eb758609c04d6b88b95f240f95b7 552 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 389 409 2.8E-8 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS09270 7814eb758609c04d6b88b95f240f95b7 552 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 456 474 2.8E-8 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS09270 7814eb758609c04d6b88b95f240f95b7 552 Pfam PF01926 50S ribosome-binding GTPase 389 507 1.0E-21 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS09270 7814eb758609c04d6b88b95f240f95b7 552 Pfam PF16360 GTP-binding GTPase Middle Region 303 381 3.9E-30 T 22-04-2016 IPR032305 GTP-binding protein, middle domain HRM2_RS09270 7814eb758609c04d6b88b95f240f95b7 552 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 198 546 5.9E-135 T 22-04-2016 IPR016496 GTPase HflX GO:0005525 HRM2_RS14325 67be78919a4c3da2721064bd801d8c89 243 PANTHER PTHR26402 7 121 2.3E-14 T 22-04-2016 HRM2_RS14325 67be78919a4c3da2721064bd801d8c89 243 Pfam PF00072 Response regulator receiver domain 9 121 7.9E-11 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS14325 67be78919a4c3da2721064bd801d8c89 243 Gene3D G3DSA:3.40.50.2300 7 130 4.9E-20 T 22-04-2016 HRM2_RS14325 67be78919a4c3da2721064bd801d8c89 243 SUPERFAMILY SSF52172 7 181 4.98E-22 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS14325 67be78919a4c3da2721064bd801d8c89 243 SMART SM00448 7 121 7.9E-11 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 SMART SM01231 329 389 2.1E-13 T 22-04-2016 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 SMART SM00448 943 1057 1.4E-22 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 Gene3D G3DSA:1.10.287.560 331 390 3.0E-14 T 22-04-2016 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 SUPERFAMILY SSF50341 796 918 2.09E-15 T 22-04-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 SMART SM00073 3 103 4.9E-22 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 PANTHER PTHR22617 1 650 3.8E-174 T 22-04-2016 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 PANTHER PTHR22617 701 776 3.8E-174 T 22-04-2016 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 Pfam PF01584 CheW-like domain 700 764 3.5E-10 T 22-04-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 Pfam PF01584 CheW-like domain 585 644 4.9E-6 T 22-04-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 Pfam PF01584 CheW-like domain 795 921 2.4E-10 T 22-04-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 437 576 9.9E-14 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 SUPERFAMILY SSF50341 697 760 9.02E-14 T 22-04-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 Pfam PF01627 Hpt domain 6 101 1.5E-18 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 Gene3D G3DSA:2.40.50.180 696 716 2.5E-11 T 22-04-2016 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 Gene3D G3DSA:2.40.50.180 611 644 2.5E-11 T 22-04-2016 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 Gene3D G3DSA:2.40.50.180 814 876 5.0E-15 T 22-04-2016 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 PANTHER PTHR22617:SF6 1 650 3.8E-174 T 22-04-2016 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 PANTHER PTHR22617:SF6 701 776 3.8E-174 T 22-04-2016 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 SMART SM00260 790 919 2.4E-4 T 22-04-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 SMART SM00260 569 761 2.1E-26 T 22-04-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 331 388 7.2E-11 T 22-04-2016 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 Pfam PF00072 Response regulator receiver domain 945 1057 1.7E-20 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 SUPERFAMILY SSF47226 4 116 3.93E-26 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 SUPERFAMILY SSF52172 944 1061 3.56E-26 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 Gene3D G3DSA:3.40.50.2300 942 1061 3.1E-27 T 22-04-2016 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 PRINTS PR00344 Bacterial sensor protein C-terminal signature 537 555 1.8E-9 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 PRINTS PR00344 Bacterial sensor protein C-terminal signature 561 574 1.8E-9 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 PRINTS PR00344 Bacterial sensor protein C-terminal signature 479 493 1.8E-9 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 SUPERFAMILY SSF55874 392 575 5.24E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 Gene3D G3DSA:2.30.30.40 577 598 7.7E-23 T 22-04-2016 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 Gene3D G3DSA:2.30.30.40 717 760 7.7E-23 T 22-04-2016 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 SUPERFAMILY SSF50341 571 645 1.01E-9 T 22-04-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 SMART SM00387 434 577 4.6E-19 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 Gene3D G3DSA:3.30.565.10 391 576 4.9E-33 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 SUPERFAMILY SSF47384 331 390 1.49E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS18010 f6f61680296c58cfa700522eb285567a 1063 Gene3D G3DSA:1.20.120.160 3 137 1.9E-35 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HRM2_RS02330 f311c17ea4be96dbb5c5db02b54aa2a2 738 SUPERFAMILY SSF158682 618 732 1.7E-9 T 22-04-2016 IPR029024 TerB-like HRM2_RS02330 f311c17ea4be96dbb5c5db02b54aa2a2 738 Gene3D G3DSA:3.40.50.1820 161 410 5.3E-12 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS02330 f311c17ea4be96dbb5c5db02b54aa2a2 738 SUPERFAMILY SSF53474 113 397 2.13E-24 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS02330 f311c17ea4be96dbb5c5db02b54aa2a2 738 Pfam PF05099 Tellurite resistance protein TerB 609 731 1.0E-6 T 22-04-2016 IPR007791 Co-chaperone DjlA, N-terminal HRM2_RS02330 f311c17ea4be96dbb5c5db02b54aa2a2 738 Pfam PF11339 Protein of unknown function (DUF3141) 24 613 1.9E-231 T 22-04-2016 IPR024501 Protein of unknown function DUF3141 HRM2_RS02330 f311c17ea4be96dbb5c5db02b54aa2a2 738 Gene3D G3DSA:1.10.3680.10 615 731 3.1E-5 T 22-04-2016 IPR029024 TerB-like HRM2_RS11785 4f6fe1544cfe5f6c6e704eb0cc4c31ca 299 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 26 291 1.3E-33 T 22-04-2016 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal HRM2_RS11785 4f6fe1544cfe5f6c6e704eb0cc4c31ca 299 PANTHER PTHR41373 4 296 6.5E-52 T 22-04-2016 HRM2_RS11785 4f6fe1544cfe5f6c6e704eb0cc4c31ca 299 Gene3D G3DSA:3.40.630.30 13 133 3.0E-16 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS11785 4f6fe1544cfe5f6c6e704eb0cc4c31ca 299 SUPERFAMILY SSF55729 14 137 1.38E-15 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS11785 4f6fe1544cfe5f6c6e704eb0cc4c31ca 299 SUPERFAMILY SSF55729 139 293 2.75E-46 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS11785 4f6fe1544cfe5f6c6e704eb0cc4c31ca 299 PIRSF PIRSF018688 4 296 2.5E-66 T 22-04-2016 IPR016732 Uncharacterised conserved protein UCP018688 HRM2_RS11785 4f6fe1544cfe5f6c6e704eb0cc4c31ca 299 Gene3D G3DSA:3.40.630.30 134 287 2.3E-51 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS01325 c94f79550fca7539351f6606312b2718 431 PIRSF PIRSF001369 37 431 2.2E-139 T 22-04-2016 IPR024176 Citrate synthase, bacterial-type UniPathway: UPA00223 HRM2_RS01325 c94f79550fca7539351f6606312b2718 431 SUPERFAMILY SSF48256 3 431 9.94E-146 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 HRM2_RS01325 c94f79550fca7539351f6606312b2718 431 PRINTS PR00143 Citrate synthase signature 362 378 6.1E-50 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 HRM2_RS01325 c94f79550fca7539351f6606312b2718 431 PRINTS PR00143 Citrate synthase signature 294 314 6.1E-50 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 HRM2_RS01325 c94f79550fca7539351f6606312b2718 431 PRINTS PR00143 Citrate synthase signature 216 231 6.1E-50 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 HRM2_RS01325 c94f79550fca7539351f6606312b2718 431 PRINTS PR00143 Citrate synthase signature 238 266 6.1E-50 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 HRM2_RS01325 c94f79550fca7539351f6606312b2718 431 PRINTS PR00143 Citrate synthase signature 162 175 6.1E-50 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 HRM2_RS01325 c94f79550fca7539351f6606312b2718 431 PRINTS PR00143 Citrate synthase signature 382 396 6.1E-50 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 HRM2_RS01325 c94f79550fca7539351f6606312b2718 431 PANTHER PTHR11739 10 431 1.8E-165 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 HRM2_RS01325 c94f79550fca7539351f6606312b2718 431 Pfam PF00285 Citrate synthase, C-terminal domain 45 414 5.6E-128 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 HRM2_RS01325 c94f79550fca7539351f6606312b2718 431 Gene3D G3DSA:1.10.580.10 51 277 9.9E-84 T 22-04-2016 IPR016142 Citrate synthase-like, large alpha subdomain UniPathway: UPA00223 HRM2_RS01325 c94f79550fca7539351f6606312b2718 431 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 12 424 3.9E-156 T 22-04-2016 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 UniPathway: UPA00223 HRM2_RS01325 c94f79550fca7539351f6606312b2718 431 ProSitePatterns PS00480 Citrate synthase signature. 301 313 - T 22-04-2016 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 UniPathway: UPA00223 HRM2_RS01325 c94f79550fca7539351f6606312b2718 431 Gene3D G3DSA:1.10.230.10 278 376 5.9E-36 T 22-04-2016 IPR016143 Citrate synthase-like, small alpha subdomain HRM2_RS14215 97e0e703f00af55e7e8a760299a9e1da 694 Pfam PF00072 Response regulator receiver domain 575 684 4.5E-16 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS14215 97e0e703f00af55e7e8a760299a9e1da 694 PRINTS PR00344 Bacterial sensor protein C-terminal signature 539 552 1.4E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS14215 97e0e703f00af55e7e8a760299a9e1da 694 PRINTS PR00344 Bacterial sensor protein C-terminal signature 484 498 1.4E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS14215 97e0e703f00af55e7e8a760299a9e1da 694 PRINTS PR00344 Bacterial sensor protein C-terminal signature 502 512 1.4E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS14215 97e0e703f00af55e7e8a760299a9e1da 694 PRINTS PR00344 Bacterial sensor protein C-terminal signature 515 533 1.4E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS14215 97e0e703f00af55e7e8a760299a9e1da 694 Gene3D G3DSA:3.30.565.10 393 552 3.2E-37 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS14215 97e0e703f00af55e7e8a760299a9e1da 694 Gene3D G3DSA:3.40.50.2300 573 693 1.3E-26 T 22-04-2016 HRM2_RS14215 97e0e703f00af55e7e8a760299a9e1da 694 SUPERFAMILY SSF55874 383 557 6.68E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS14215 97e0e703f00af55e7e8a760299a9e1da 694 PANTHER PTHR24423:SF544 185 694 3.5E-120 T 22-04-2016 HRM2_RS14215 97e0e703f00af55e7e8a760299a9e1da 694 SMART SM00388 327 393 0.0019 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS14215 97e0e703f00af55e7e8a760299a9e1da 694 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 433 552 5.6E-19 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS14215 97e0e703f00af55e7e8a760299a9e1da 694 SMART SM00387 433 555 5.3E-31 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS14215 97e0e703f00af55e7e8a760299a9e1da 694 Pfam PF00989 PAS fold 190 301 3.0E-9 T 22-04-2016 IPR013767 PAS fold GO:0006355 HRM2_RS14215 97e0e703f00af55e7e8a760299a9e1da 694 SUPERFAMILY SSF47384 323 390 1.55E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS14215 97e0e703f00af55e7e8a760299a9e1da 694 Gene3D G3DSA:3.30.450.20 184 301 1.3E-23 T 22-04-2016 HRM2_RS14215 97e0e703f00af55e7e8a760299a9e1da 694 PANTHER PTHR24423 185 694 3.5E-120 T 22-04-2016 HRM2_RS14215 97e0e703f00af55e7e8a760299a9e1da 694 Gene3D G3DSA:3.30.450.40 35 176 1.7E-6 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS14215 97e0e703f00af55e7e8a760299a9e1da 694 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 188 311 7.2E-21 T 22-04-2016 IPR000014 PAS domain HRM2_RS14215 97e0e703f00af55e7e8a760299a9e1da 694 SMART SM00091 190 256 1.8E-7 T 22-04-2016 IPR000014 PAS domain HRM2_RS14215 97e0e703f00af55e7e8a760299a9e1da 694 SMART SM00448 573 686 5.3E-18 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS14215 97e0e703f00af55e7e8a760299a9e1da 694 Pfam PF01590 GAF domain 36 173 3.0E-4 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS14215 97e0e703f00af55e7e8a760299a9e1da 694 SUPERFAMILY SSF52172 573 693 6.12E-25 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS14215 97e0e703f00af55e7e8a760299a9e1da 694 SUPERFAMILY SSF55781 38 177 2.04E-7 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS14215 97e0e703f00af55e7e8a760299a9e1da 694 SUPERFAMILY SSF55785 183 303 4.71E-23 T 22-04-2016 IPR000014 PAS domain HRM2_RS17850 41091512060983ce6e0c848a06108717 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 4.1E-59 T 22-04-2016 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 HRM2_RS17850 41091512060983ce6e0c848a06108717 122 SMART SM01374 1 122 5.6E-90 T 22-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 HRM2_RS17850 41091512060983ce6e0c848a06108717 122 PANTHER PTHR11761 1 122 1.9E-76 T 22-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 HRM2_RS17850 41091512060983ce6e0c848a06108717 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 1.6E-57 T 22-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 HRM2_RS17850 41091512060983ce6e0c848a06108717 122 SUPERFAMILY SSF50193 1 122 2.49E-53 T 22-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 HRM2_RS17850 41091512060983ce6e0c848a06108717 122 Gene3D G3DSA:2.40.150.20 1 122 2.8E-57 T 22-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 HRM2_RS17850 41091512060983ce6e0c848a06108717 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.973 T 22-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 HRM2_RS17850 41091512060983ce6e0c848a06108717 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 22-04-2016 IPR019972 Ribosomal protein L14P, conserved site HRM2_RS13745 b94bf544aca70ecfcd00052f1b1ec13c 426 SUPERFAMILY SSF51556 57 368 7.99E-108 T 22-04-2016 IPR032466 Metal-dependent hydrolase HRM2_RS13745 b94bf544aca70ecfcd00052f1b1ec13c 426 Gene3D G3DSA:2.30.40.10 5 71 3.3E-15 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS13745 b94bf544aca70ecfcd00052f1b1ec13c 426 ProSitePatterns PS00483 Dihydroorotase signature 2. 305 316 - T 22-04-2016 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 HRM2_RS13745 b94bf544aca70ecfcd00052f1b1ec13c 426 Hamap MF_00220_B Dihydroorotase [pyrC]. 2 425 41.931 T 22-04-2016 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 HRM2_RS13745 b94bf544aca70ecfcd00052f1b1ec13c 426 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 18 423 8.0E-127 T 22-04-2016 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 HRM2_RS13745 b94bf544aca70ecfcd00052f1b1ec13c 426 SUPERFAMILY SSF51338 367 423 1.43E-23 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS13745 b94bf544aca70ecfcd00052f1b1ec13c 426 SUPERFAMILY SSF51338 4 56 1.43E-23 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS13745 b94bf544aca70ecfcd00052f1b1ec13c 426 ProSitePatterns PS00482 Dihydroorotase signature 1. 60 68 - T 22-04-2016 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 HRM2_RS13745 b94bf544aca70ecfcd00052f1b1ec13c 426 PANTHER PTHR11647 1 425 5.1E-172 T 22-04-2016 HRM2_RS13745 b94bf544aca70ecfcd00052f1b1ec13c 426 Pfam PF01979 Amidohydrolase family 54 420 6.9E-38 T 22-04-2016 IPR006680 Amidohydrolase-related GO:0016787 HRM2_RS13745 b94bf544aca70ecfcd00052f1b1ec13c 426 Gene3D G3DSA:3.20.20.140 72 406 5.7E-111 T 22-04-2016 HRM2_RS13745 b94bf544aca70ecfcd00052f1b1ec13c 426 PANTHER PTHR11647:SF70 1 425 5.1E-172 T 22-04-2016 HRM2_RS00945 d8ac9172356f6417d870b78a9ea4a2f3 225 SUPERFAMILY SSF48498 89 201 1.36E-19 T 22-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal HRM2_RS00945 d8ac9172356f6417d870b78a9ea4a2f3 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 64 1.2E-9 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS00945 d8ac9172356f6417d870b78a9ea4a2f3 225 PANTHER PTHR30328:SF7 14 203 1.3E-29 T 22-04-2016 HRM2_RS00945 d8ac9172356f6417d870b78a9ea4a2f3 225 SUPERFAMILY SSF46689 12 94 3.84E-15 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS00945 d8ac9172356f6417d870b78a9ea4a2f3 225 Gene3D G3DSA:1.10.357.10 9 203 3.2E-41 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HRM2_RS00945 d8ac9172356f6417d870b78a9ea4a2f3 225 PANTHER PTHR30328 14 203 1.3E-29 T 22-04-2016 HRM2_RS00945 d8ac9172356f6417d870b78a9ea4a2f3 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 1.2E-5 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS00945 d8ac9172356f6417d870b78a9ea4a2f3 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 1.2E-5 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS05240 ba94dc9cc3e132080b644b5c57ed284d 416 PRINTS PR01182 Ornithine decarboxylase signature 346 356 7.7E-7 T 22-04-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 HRM2_RS05240 ba94dc9cc3e132080b644b5c57ed284d 416 PRINTS PR01182 Ornithine decarboxylase signature 366 379 7.7E-7 T 22-04-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 HRM2_RS05240 ba94dc9cc3e132080b644b5c57ed284d 416 PRINTS PR01182 Ornithine decarboxylase signature 17 41 7.7E-7 T 22-04-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 HRM2_RS05240 ba94dc9cc3e132080b644b5c57ed284d 416 PRINTS PR01182 Ornithine decarboxylase signature 43 70 7.7E-7 T 22-04-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 HRM2_RS05240 ba94dc9cc3e132080b644b5c57ed284d 416 PRINTS PR01182 Ornithine decarboxylase signature 87 111 7.7E-7 T 22-04-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 HRM2_RS05240 ba94dc9cc3e132080b644b5c57ed284d 416 SUPERFAMILY SSF50621 240 406 3.35E-27 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 HRM2_RS05240 ba94dc9cc3e132080b644b5c57ed284d 416 PANTHER PTHR11482 8 322 4.6E-61 T 22-04-2016 HRM2_RS05240 ba94dc9cc3e132080b644b5c57ed284d 416 PANTHER PTHR11482 342 386 4.6E-61 T 22-04-2016 HRM2_RS05240 ba94dc9cc3e132080b644b5c57ed284d 416 Gene3D G3DSA:2.40.37.10 257 406 9.8E-28 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 HRM2_RS05240 ba94dc9cc3e132080b644b5c57ed284d 416 Gene3D G3DSA:3.20.20.10 25 256 5.3E-51 T 22-04-2016 IPR029066 PLP-binding barrel HRM2_RS05240 ba94dc9cc3e132080b644b5c57ed284d 416 SUPERFAMILY SSF51419 19 270 9.42E-53 T 22-04-2016 IPR029066 PLP-binding barrel HRM2_RS05240 ba94dc9cc3e132080b644b5c57ed284d 416 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 27 267 1.6E-30 T 22-04-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Reactome: REACT_13 HRM2_RS05240 ba94dc9cc3e132080b644b5c57ed284d 416 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 210 223 - T 22-04-2016 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site Reactome: REACT_13 HRM2_RS05240 ba94dc9cc3e132080b644b5c57ed284d 416 PANTHER PTHR11482:SF5 8 322 4.6E-61 T 22-04-2016 HRM2_RS05240 ba94dc9cc3e132080b644b5c57ed284d 416 PANTHER PTHR11482:SF5 342 386 4.6E-61 T 22-04-2016 HRM2_RS05240 ba94dc9cc3e132080b644b5c57ed284d 416 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 65 77 1.1E-9 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 HRM2_RS05240 ba94dc9cc3e132080b644b5c57ed284d 416 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 171 184 1.1E-9 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 HRM2_RS05240 ba94dc9cc3e132080b644b5c57ed284d 416 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 45 63 1.1E-9 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 HRM2_RS05240 ba94dc9cc3e132080b644b5c57ed284d 416 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 258 277 1.1E-9 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 HRM2_RS05240 ba94dc9cc3e132080b644b5c57ed284d 416 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 322 394 1.8E-8 T 22-04-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 HRM2_RS21735 67936395c01794f53cad4b8b89ae5e08 677 SUPERFAMILY SSF111326 92 648 2.09E-217 T 22-04-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 HRM2_RS21735 67936395c01794f53cad4b8b89ae5e08 677 PANTHER PTHR12216:SF3 8 675 0.0 T 22-04-2016 HRM2_RS21735 67936395c01794f53cad4b8b89ae5e08 677 Gene3D G3DSA:3.40.50.10730 221 443 2.2E-77 T 22-04-2016 HRM2_RS21735 67936395c01794f53cad4b8b89ae5e08 677 Pfam PF01175 Urocanase 92 644 8.1E-233 T 22-04-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 HRM2_RS21735 67936395c01794f53cad4b8b89ae5e08 677 Hamap MF_00577 Urocanate hydratase [hutU]. 62 663 41.866 T 22-04-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 HRM2_RS21735 67936395c01794f53cad4b8b89ae5e08 677 TIGRFAM TIGR01228 hutU: urocanate hydratase 102 644 9.1E-130 T 22-04-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 HRM2_RS21735 67936395c01794f53cad4b8b89ae5e08 677 PANTHER PTHR12216 8 675 0.0 T 22-04-2016 HRM2_RS21735 67936395c01794f53cad4b8b89ae5e08 677 ProSitePatterns PS01233 Urocanase signature. 541 556 - T 22-04-2016 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 HRM2_RS21735 67936395c01794f53cad4b8b89ae5e08 677 Gene3D G3DSA:3.40.1770.10 455 648 6.9E-147 T 22-04-2016 HRM2_RS21735 67936395c01794f53cad4b8b89ae5e08 677 Gene3D G3DSA:3.40.1770.10 86 220 6.9E-147 T 22-04-2016 HRM2_RS21735 67936395c01794f53cad4b8b89ae5e08 677 PIRSF PIRSF001423 83 666 5.4E-175 T 22-04-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 HRM2_RS05270 66f560fe191b06801a3f1b5a83132226 357 PANTHER PTHR32154 1 354 1.4E-136 T 22-04-2016 HRM2_RS05270 66f560fe191b06801a3f1b5a83132226 357 SUPERFAMILY SSF52518 1 233 8.03E-59 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS05270 66f560fe191b06801a3f1b5a83132226 357 Gene3D G3DSA:3.40.50.970 2 184 3.6E-67 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS05270 66f560fe191b06801a3f1b5a83132226 357 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 14 196 8.9E-50 T 22-04-2016 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 HRM2_RS05270 66f560fe191b06801a3f1b5a83132226 357 Gene3D G3DSA:3.40.50.920 245 355 7.8E-23 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HRM2_RS05270 66f560fe191b06801a3f1b5a83132226 357 SUPERFAMILY SSF52922 248 357 2.22E-19 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HRM2_RS05270 66f560fe191b06801a3f1b5a83132226 357 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 253 347 6.1E-23 T 22-04-2016 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II HRM2_RS05270 66f560fe191b06801a3f1b5a83132226 357 PANTHER PTHR32154:SF19 1 354 1.4E-136 T 22-04-2016 HRM2_RS18645 a1eaf77b0c0bf2e3e9a2c8be6138e55f 264 SMART SM00382 31 225 1.0E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS18645 a1eaf77b0c0bf2e3e9a2c8be6138e55f 264 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS18645 a1eaf77b0c0bf2e3e9a2c8be6138e55f 264 Pfam PF00005 ABC transporter 23 176 8.2E-29 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS18645 a1eaf77b0c0bf2e3e9a2c8be6138e55f 264 PANTHER PTHR24220:SF534 3 250 2.7E-106 T 22-04-2016 HRM2_RS18645 a1eaf77b0c0bf2e3e9a2c8be6138e55f 264 Gene3D G3DSA:3.40.50.300 1 233 1.7E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18645 a1eaf77b0c0bf2e3e9a2c8be6138e55f 264 PANTHER PTHR24220 3 250 2.7E-106 T 22-04-2016 HRM2_RS18645 a1eaf77b0c0bf2e3e9a2c8be6138e55f 264 SUPERFAMILY SSF52540 1 233 1.6E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10670 102546af7a1627d098feb8996fa82c1f 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 305 1.8E-35 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS10670 102546af7a1627d098feb8996fa82c1f 307 PANTHER PTHR30465:SF59 1 306 3.5E-131 T 22-04-2016 HRM2_RS10670 102546af7a1627d098feb8996fa82c1f 307 SUPERFAMILY SSF161098 95 288 1.28E-20 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS10670 102546af7a1627d098feb8996fa82c1f 307 Gene3D G3DSA:1.10.3720.10 96 299 5.8E-20 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS10670 102546af7a1627d098feb8996fa82c1f 307 PANTHER PTHR30465 1 306 3.5E-131 T 22-04-2016 HRM2_RS18750 6951d22c8bd0c619db2bf5882f87c090 156 Gene3D G3DSA:1.10.150.120 75 153 4.8E-35 T 22-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 HRM2_RS18750 6951d22c8bd0c619db2bf5882f87c090 156 SUPERFAMILY SSF54292 2 78 1.14E-22 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 HRM2_RS18750 6951d22c8bd0c619db2bf5882f87c090 156 PANTHER PTHR11908 1 145 2.6E-37 T 22-04-2016 HRM2_RS18750 6951d22c8bd0c619db2bf5882f87c090 156 Gene3D G3DSA:3.10.20.30 2 74 7.1E-26 T 22-04-2016 IPR012675 Beta-grasp domain HRM2_RS18750 6951d22c8bd0c619db2bf5882f87c090 156 PANTHER PTHR11908:SF66 1 145 2.6E-37 T 22-04-2016 HRM2_RS18750 6951d22c8bd0c619db2bf5882f87c090 156 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 39 47 - T 22-04-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 HRM2_RS18750 6951d22c8bd0c619db2bf5882f87c090 156 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 52 4.5E-4 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 HRM2_RS18750 6951d22c8bd0c619db2bf5882f87c090 156 SUPERFAMILY SSF47741 73 152 1.83E-31 T 22-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 HRM2_RS18750 6951d22c8bd0c619db2bf5882f87c090 156 Pfam PF01799 [2Fe-2S] binding domain 73 144 3.6E-31 T 22-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 HRM2_RS15065 fb6c72e5bf4fc19ce0d2ca717aa94624 214 Pfam PF14520 Helix-hairpin-helix domain 76 131 1.2E-7 T 22-04-2016 HRM2_RS15065 fb6c72e5bf4fc19ce0d2ca717aa94624 214 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 212 18.435 T 22-04-2016 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 HRM2_RS15065 fb6c72e5bf4fc19ce0d2ca717aa94624 214 SUPERFAMILY SSF50249 1 67 2.97E-5 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS15065 fb6c72e5bf4fc19ce0d2ca717aa94624 214 Gene3D G3DSA:1.10.150.20 71 138 1.7E-16 T 22-04-2016 HRM2_RS15065 fb6c72e5bf4fc19ce0d2ca717aa94624 214 Gene3D G3DSA:2.40.50.140 1 69 1.6E-11 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS15065 fb6c72e5bf4fc19ce0d2ca717aa94624 214 SUPERFAMILY SSF47781 70 138 1.45E-12 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 HRM2_RS15065 fb6c72e5bf4fc19ce0d2ca717aa94624 214 PANTHER PTHR33796 2 214 5.7E-32 T 22-04-2016 HRM2_RS15065 fb6c72e5bf4fc19ce0d2ca717aa94624 214 Pfam PF01330 RuvA N terminal domain 1 57 5.6E-10 T 22-04-2016 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 HRM2_RS01015 fef3fb8ab6827ac310a557a3d84f686f 160 Pfam PF13581 Histidine kinase-like ATPase domain 31 155 2.1E-25 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS01015 fef3fb8ab6827ac310a557a3d84f686f 160 SUPERFAMILY SSF55874 56 151 4.71E-11 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS01015 fef3fb8ab6827ac310a557a3d84f686f 160 PANTHER PTHR35526 10 160 2.0E-15 T 22-04-2016 HRM2_RS01015 fef3fb8ab6827ac310a557a3d84f686f 160 Gene3D G3DSA:3.30.565.10 45 149 2.4E-9 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS01015 fef3fb8ab6827ac310a557a3d84f686f 160 PANTHER PTHR35526:SF1 10 160 2.0E-15 T 22-04-2016 HRM2_RS23665 b6315a2413328826d4f5f066281f1e81 186 SUPERFAMILY SSF109604 22 140 6.81E-11 T 22-04-2016 HRM2_RS23665 b6315a2413328826d4f5f066281f1e81 186 Gene3D G3DSA:1.10.3210.10 21 160 3.4E-9 T 22-04-2016 IPR006674 HD domain HRM2_RS05555 beba20c94da92677ce560fbb7f956304 411 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 172 200 - T 22-04-2016 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 HRM2_RS05555 beba20c94da92677ce560fbb7f956304 411 PANTHER PTHR30012:SF0 2 411 1.7E-134 T 22-04-2016 HRM2_RS05555 beba20c94da92677ce560fbb7f956304 411 Pfam PF00482 Type II secretion system (T2SS), protein F 280 402 8.6E-27 T 22-04-2016 IPR018076 Type II secretion system F domain HRM2_RS05555 beba20c94da92677ce560fbb7f956304 411 Pfam PF00482 Type II secretion system (T2SS), protein F 78 200 2.7E-33 T 22-04-2016 IPR018076 Type II secretion system F domain HRM2_RS05555 beba20c94da92677ce560fbb7f956304 411 PRINTS PR00812 Bacterial general secretion pathway protein F signature 375 389 6.8E-27 T 22-04-2016 IPR003004 GspF/PilC family HRM2_RS05555 beba20c94da92677ce560fbb7f956304 411 PRINTS PR00812 Bacterial general secretion pathway protein F signature 73 85 6.8E-27 T 22-04-2016 IPR003004 GspF/PilC family HRM2_RS05555 beba20c94da92677ce560fbb7f956304 411 PRINTS PR00812 Bacterial general secretion pathway protein F signature 172 200 6.8E-27 T 22-04-2016 IPR003004 GspF/PilC family HRM2_RS05555 beba20c94da92677ce560fbb7f956304 411 PRINTS PR00812 Bacterial general secretion pathway protein F signature 391 410 6.8E-27 T 22-04-2016 IPR003004 GspF/PilC family HRM2_RS05555 beba20c94da92677ce560fbb7f956304 411 PANTHER PTHR30012 2 411 1.7E-134 T 22-04-2016 HRM2_RS05555 beba20c94da92677ce560fbb7f956304 411 TIGRFAM TIGR02120 GspF: type II secretion system protein F 4 410 3.0E-130 T 22-04-2016 IPR011850 General secretion pathway protein F GO:0008565|GO:0015627|GO:0015628 HRM2_RS01275 350d2125bde6cce321880b4eb7c52eea 220 Gene3D G3DSA:3.40.50.2300 2 120 9.1E-34 T 22-04-2016 HRM2_RS01275 350d2125bde6cce321880b4eb7c52eea 220 SMART SM00421 149 206 1.6E-22 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS01275 350d2125bde6cce321880b4eb7c52eea 220 PANTHER PTHR26402 3 212 2.2E-66 T 22-04-2016 HRM2_RS01275 350d2125bde6cce321880b4eb7c52eea 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 206 1.4E-19 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS01275 350d2125bde6cce321880b4eb7c52eea 220 SMART SM00448 3 115 1.4E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS01275 350d2125bde6cce321880b4eb7c52eea 220 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS01275 350d2125bde6cce321880b4eb7c52eea 220 SUPERFAMILY SSF52172 1 132 4.27E-33 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS01275 350d2125bde6cce321880b4eb7c52eea 220 PANTHER PTHR26402:SF151 3 212 2.2E-66 T 22-04-2016 HRM2_RS01275 350d2125bde6cce321880b4eb7c52eea 220 Gene3D G3DSA:1.10.10.10 121 213 3.5E-28 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS01275 350d2125bde6cce321880b4eb7c52eea 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 3.8E-14 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS01275 350d2125bde6cce321880b4eb7c52eea 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 3.8E-14 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS01275 350d2125bde6cce321880b4eb7c52eea 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 3.8E-14 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS01275 350d2125bde6cce321880b4eb7c52eea 220 SUPERFAMILY SSF46894 144 213 1.39E-20 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HRM2_RS01275 350d2125bde6cce321880b4eb7c52eea 220 Pfam PF00072 Response regulator receiver domain 5 116 2.1E-25 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS19170 3c5dd85ec2a78ecda822d020bcd06127 320 Gene3D G3DSA:3.40.50.720 1 208 4.0E-45 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS19170 3c5dd85ec2a78ecda822d020bcd06127 320 PANTHER PTHR10366:SF12 3 317 5.3E-103 T 22-04-2016 HRM2_RS19170 3c5dd85ec2a78ecda822d020bcd06127 320 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 199 1.8E-26 T 22-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 HRM2_RS19170 3c5dd85ec2a78ecda822d020bcd06127 320 PANTHER PTHR10366 3 317 5.3E-103 T 22-04-2016 HRM2_RS19170 3c5dd85ec2a78ecda822d020bcd06127 320 Gene3D G3DSA:3.90.25.10 209 309 1.3E-4 T 22-04-2016 HRM2_RS19170 3c5dd85ec2a78ecda822d020bcd06127 320 SUPERFAMILY SSF51735 1 312 1.4E-56 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS12500 6c3b5ae88a29ba53b443e89f9a8c00df 463 PANTHER PTHR22573:SF15 1 460 1.6E-137 T 22-04-2016 HRM2_RS12500 6c3b5ae88a29ba53b443e89f9a8c00df 463 Gene3D G3DSA:3.40.120.10 3 134 3.6E-42 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS12500 6c3b5ae88a29ba53b443e89f9a8c00df 463 SUPERFAMILY SSF53738 3 196 1.92E-39 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS12500 6c3b5ae88a29ba53b443e89f9a8c00df 463 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 133 2.9E-38 T 22-04-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS12500 6c3b5ae88a29ba53b443e89f9a8c00df 463 Gene3D G3DSA:3.40.120.10 191 265 2.7E-24 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS12500 6c3b5ae88a29ba53b443e89f9a8c00df 463 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 1.5E-14 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS12500 6c3b5ae88a29ba53b443e89f9a8c00df 463 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 249 264 1.5E-14 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS12500 6c3b5ae88a29ba53b443e89f9a8c00df 463 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 189 208 1.5E-14 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS12500 6c3b5ae88a29ba53b443e89f9a8c00df 463 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 95 104 - T 22-04-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS12500 6c3b5ae88a29ba53b443e89f9a8c00df 463 Gene3D G3DSA:3.40.120.10 266 382 1.2E-31 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS12500 6c3b5ae88a29ba53b443e89f9a8c00df 463 Gene3D G3DSA:3.30.310.50 385 460 6.5E-13 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS12500 6c3b5ae88a29ba53b443e89f9a8c00df 463 SUPERFAMILY SSF53738 168 270 6.67E-25 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS12500 6c3b5ae88a29ba53b443e89f9a8c00df 463 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 461 40.623 T 22-04-2016 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS12500 6c3b5ae88a29ba53b443e89f9a8c00df 463 PANTHER PTHR22573 1 460 1.6E-137 T 22-04-2016 HRM2_RS12500 6c3b5ae88a29ba53b443e89f9a8c00df 463 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 273 383 7.5E-30 T 22-04-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS12500 6c3b5ae88a29ba53b443e89f9a8c00df 463 SUPERFAMILY SSF53738 274 379 3.06E-28 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS12500 6c3b5ae88a29ba53b443e89f9a8c00df 463 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 390 458 4.7E-11 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS12500 6c3b5ae88a29ba53b443e89f9a8c00df 463 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 459 7.3E-155 T 22-04-2016 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS12500 6c3b5ae88a29ba53b443e89f9a8c00df 463 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 177 269 1.8E-17 T 22-04-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS12500 6c3b5ae88a29ba53b443e89f9a8c00df 463 SUPERFAMILY SSF55957 373 461 6.1E-20 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS24860 73269082e67bc9390626650997902633 138 SUPERFAMILY SSF52172 7 130 8.54E-27 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS24860 73269082e67bc9390626650997902633 138 SMART SM00448 8 117 2.6E-18 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS24860 73269082e67bc9390626650997902633 138 PANTHER PTHR26402 8 117 1.8E-24 T 22-04-2016 HRM2_RS24860 73269082e67bc9390626650997902633 138 Pfam PF00072 Response regulator receiver domain 10 90 2.6E-16 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS24860 73269082e67bc9390626650997902633 138 Gene3D G3DSA:3.40.50.2300 5 125 4.0E-24 T 22-04-2016 HRM2_RS18025 531711103fac7865be87bf4acc83b9d6 278 Gene3D G3DSA:1.10.155.10 2 71 4.2E-11 T 22-04-2016 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal HRM2_RS18025 531711103fac7865be87bf4acc83b9d6 278 Pfam PF03705 CheR methyltransferase, all-alpha domain 8 58 2.1E-10 T 22-04-2016 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal HRM2_RS18025 531711103fac7865be87bf4acc83b9d6 278 SUPERFAMILY SSF53335 74 267 1.06E-46 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS18025 531711103fac7865be87bf4acc83b9d6 278 SMART SM00138 6 276 2.2E-78 T 22-04-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HRM2_RS18025 531711103fac7865be87bf4acc83b9d6 278 Pfam PF01739 CheR methyltransferase, SAM binding domain 74 265 1.2E-53 T 22-04-2016 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal HRM2_RS18025 531711103fac7865be87bf4acc83b9d6 278 PANTHER PTHR24422 4 259 1.3E-68 T 22-04-2016 HRM2_RS18025 531711103fac7865be87bf4acc83b9d6 278 Gene3D G3DSA:3.40.50.150 73 267 4.4E-57 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS18025 531711103fac7865be87bf4acc83b9d6 278 PRINTS PR00996 Glutamate methyltransferase family signature 147 163 3.8E-31 T 22-04-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HRM2_RS18025 531711103fac7865be87bf4acc83b9d6 278 PRINTS PR00996 Glutamate methyltransferase family signature 28 41 3.8E-31 T 22-04-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HRM2_RS18025 531711103fac7865be87bf4acc83b9d6 278 PRINTS PR00996 Glutamate methyltransferase family signature 112 132 3.8E-31 T 22-04-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HRM2_RS18025 531711103fac7865be87bf4acc83b9d6 278 PRINTS PR00996 Glutamate methyltransferase family signature 234 257 3.8E-31 T 22-04-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HRM2_RS18025 531711103fac7865be87bf4acc83b9d6 278 PRINTS PR00996 Glutamate methyltransferase family signature 215 229 3.8E-31 T 22-04-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HRM2_RS18025 531711103fac7865be87bf4acc83b9d6 278 SUPERFAMILY SSF47757 2 73 4.05E-13 T 22-04-2016 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal HRM2_RS20500 bbf03ba9ba82465e192aba29470b60d0 849 Pfam PF00005 ABC transporter 352 459 1.4E-16 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS20500 bbf03ba9ba82465e192aba29470b60d0 849 Pfam PF00005 ABC transporter 661 778 1.5E-10 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS20500 bbf03ba9ba82465e192aba29470b60d0 849 SMART SM00382 361 825 2.6E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS20500 bbf03ba9ba82465e192aba29470b60d0 849 Gene3D G3DSA:1.20.1560.10 9 324 4.9E-52 T 22-04-2016 HRM2_RS20500 bbf03ba9ba82465e192aba29470b60d0 849 Gene3D G3DSA:3.40.50.300 336 460 3.4E-26 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20500 bbf03ba9ba82465e192aba29470b60d0 849 SUPERFAMILY SSF52540 738 834 2.19E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20500 bbf03ba9ba82465e192aba29470b60d0 849 SUPERFAMILY SSF52540 338 455 2.19E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20500 bbf03ba9ba82465e192aba29470b60d0 849 Pfam PF00664 ABC transporter transmembrane region 24 281 2.0E-23 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HRM2_RS20500 bbf03ba9ba82465e192aba29470b60d0 849 Gene3D G3DSA:3.40.50.300 727 846 7.7E-33 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20500 bbf03ba9ba82465e192aba29470b60d0 849 PANTHER PTHR24221:SF138 9 445 6.5E-104 T 22-04-2016 HRM2_RS20500 bbf03ba9ba82465e192aba29470b60d0 849 PANTHER PTHR24221:SF138 730 847 6.5E-104 T 22-04-2016 HRM2_RS20500 bbf03ba9ba82465e192aba29470b60d0 849 SUPERFAMILY SSF90123 4 324 5.23E-54 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HRM2_RS20500 bbf03ba9ba82465e192aba29470b60d0 849 ProSitePatterns PS00211 ABC transporters family signature. 750 764 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS20500 bbf03ba9ba82465e192aba29470b60d0 849 PANTHER PTHR24221 9 445 6.5E-104 T 22-04-2016 HRM2_RS20500 bbf03ba9ba82465e192aba29470b60d0 849 PANTHER PTHR24221 730 847 6.5E-104 T 22-04-2016 HRM2_RS06460 0481250e91d357013f50896f474b435d 200 PANTHER PTHR33508 2 200 1.5E-57 T 22-04-2016 HRM2_RS06460 0481250e91d357013f50896f474b435d 200 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 3 193 4.2E-35 T 22-04-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 HRM2_RS06460 0481250e91d357013f50896f474b435d 200 PANTHER PTHR33508:SF1 2 200 1.5E-57 T 22-04-2016 HRM2_RS06460 0481250e91d357013f50896f474b435d 200 Pfam PF01914 MarC family integral membrane protein 4 196 1.1E-39 T 22-04-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 Pfam PF14559 Tetratricopeptide repeat 189 233 1.5E-5 T 22-04-2016 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 Pfam PF14559 Tetratricopeptide repeat 285 345 2.7E-8 T 22-04-2016 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 Pfam PF14559 Tetratricopeptide repeat 380 436 1.9E-8 T 22-04-2016 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 Pfam PF13432 Tetratricopeptide repeat 36 94 5.0E-4 T 22-04-2016 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 Pfam PF13432 Tetratricopeptide repeat 687 744 0.0067 T 22-04-2016 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 Pfam PF13432 Tetratricopeptide repeat 444 504 0.0025 T 22-04-2016 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 SUPERFAMILY SSF48452 153 406 6.07E-59 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 SUPERFAMILY SSF48452 441 535 6.07E-59 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 Gene3D G3DSA:1.25.40.10 547 755 1.2E-39 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 Pfam PF13181 Tetratricopeptide repeat 237 267 0.065 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 Pfam PF13181 Tetratricopeptide repeat 548 576 0.0089 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 Pfam PF13176 Tetratricopeptide repeat 616 644 0.0077 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 SMART SM00028 715 748 0.32 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 SMART SM00028 132 165 440.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 SMART SM00028 681 714 2.9 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 SMART SM00028 472 505 0.076 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 SMART SM00028 200 233 390.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 SMART SM00028 268 301 0.055 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 SMART SM00028 612 645 0.0075 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 SMART SM00028 97 130 14.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 SMART SM00028 544 577 0.0013 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 SMART SM00028 29 62 64.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 SMART SM00028 234 267 0.33 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 SMART SM00028 578 611 230.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 SMART SM00028 438 471 27.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 SMART SM00028 63 96 5.4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 SMART SM00028 370 403 0.091 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 SMART SM00028 336 369 67.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 SMART SM00028 404 437 26.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 SMART SM00028 646 680 280.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 SMART SM00028 166 199 15.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 SUPERFAMILY SSF48452 31 203 1.31E-26 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 Gene3D G3DSA:1.25.40.10 21 302 4.9E-50 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 Gene3D G3DSA:1.25.40.10 309 546 2.4E-43 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 PANTHER PTHR23083 349 511 4.5E-82 T 22-04-2016 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 PANTHER PTHR23083 234 280 4.5E-82 T 22-04-2016 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 PANTHER PTHR23083 4 101 4.5E-82 T 22-04-2016 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 PANTHER PTHR23083 550 758 4.5E-82 T 22-04-2016 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 PANTHER PTHR23083 171 199 4.5E-82 T 22-04-2016 HRM2_RS11230 026d50f2d9a0339efb5e9ee1cda77830 762 SUPERFAMILY SSF48452 544 749 3.8E-32 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS16215 d53dfed2ce2e1322479c68f97a4db070 69 Gene3D G3DSA:3.30.1660.10 3 69 2.0E-22 T 22-04-2016 IPR025543 Dodecin-like HRM2_RS16215 d53dfed2ce2e1322479c68f97a4db070 69 PANTHER PTHR39324:SF1 1 69 3.6E-16 T 22-04-2016 HRM2_RS16215 d53dfed2ce2e1322479c68f97a4db070 69 SUPERFAMILY SSF89807 4 68 1.57E-19 T 22-04-2016 IPR009923 Dodecin HRM2_RS16215 d53dfed2ce2e1322479c68f97a4db070 69 Pfam PF07311 Dodecin 5 68 4.1E-23 T 22-04-2016 IPR009923 Dodecin HRM2_RS16215 d53dfed2ce2e1322479c68f97a4db070 69 PANTHER PTHR39324 1 69 3.6E-16 T 22-04-2016 HRM2_RS01295 761792035c57db6ba8dc739cceec935e 284 Pfam PF00398 Ribosomal RNA adenine dimethylase 15 268 5.1E-54 T 22-04-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm HRM2_RS01295 761792035c57db6ba8dc739cceec935e 284 SMART SM00650 29 202 2.4E-59 T 22-04-2016 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 HRM2_RS01295 761792035c57db6ba8dc739cceec935e 284 PANTHER PTHR11727 7 275 2.2E-77 T 22-04-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm HRM2_RS01295 761792035c57db6ba8dc739cceec935e 284 PANTHER PTHR11727:SF7 7 275 2.2E-77 T 22-04-2016 HRM2_RS01295 761792035c57db6ba8dc739cceec935e 284 Gene3D G3DSA:1.10.8.100 209 276 1.3E-21 T 22-04-2016 IPR023165 rRNA adenine dimethylase-like HRM2_RS01295 761792035c57db6ba8dc739cceec935e 284 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 13 276 51.959 T 22-04-2016 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 HRM2_RS01295 761792035c57db6ba8dc739cceec935e 284 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 15 274 4.0E-77 T 22-04-2016 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 HRM2_RS01295 761792035c57db6ba8dc739cceec935e 284 SUPERFAMILY SSF53335 21 276 5.78E-68 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS01295 761792035c57db6ba8dc739cceec935e 284 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 45 72 - T 22-04-2016 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 HRM2_RS01295 761792035c57db6ba8dc739cceec935e 284 Gene3D G3DSA:3.40.50.150 8 200 8.2E-62 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS09975 36a804f26e1fe987f766386b69f3bf26 668 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 213 665 1.6E-109 T 22-04-2016 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16|Reactome: REACT_71 HRM2_RS09975 36a804f26e1fe987f766386b69f3bf26 668 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 1 193 3.3E-35 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HRM2_RS09975 36a804f26e1fe987f766386b69f3bf26 668 SUPERFAMILY SSF53686 1 205 4.71E-54 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HRM2_RS09975 36a804f26e1fe987f766386b69f3bf26 668 Gene3D G3DSA:1.20.120.640 522 616 5.2E-13 T 22-04-2016 HRM2_RS09975 36a804f26e1fe987f766386b69f3bf26 668 Pfam PF09190 DALR domain 563 620 3.3E-7 T 22-04-2016 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 HRM2_RS09975 36a804f26e1fe987f766386b69f3bf26 668 Gene3D G3DSA:3.40.50.1100 47 204 3.2E-60 T 22-04-2016 HRM2_RS09975 36a804f26e1fe987f766386b69f3bf26 668 Gene3D G3DSA:3.40.50.620 230 520 1.2E-69 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS09975 36a804f26e1fe987f766386b69f3bf26 668 SUPERFAMILY SSF52374 213 528 2.68E-62 T 22-04-2016 HRM2_RS09975 36a804f26e1fe987f766386b69f3bf26 668 SUPERFAMILY SSF47323 549 667 4.19E-22 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS09975 36a804f26e1fe987f766386b69f3bf26 668 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 226 525 2.0E-79 T 22-04-2016 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 HRM2_RS09975 36a804f26e1fe987f766386b69f3bf26 668 SMART SM00840 563 626 3.1E-9 T 22-04-2016 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 HRM2_RS09975 36a804f26e1fe987f766386b69f3bf26 668 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 437 458 8.3E-16 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HRM2_RS09975 36a804f26e1fe987f766386b69f3bf26 668 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 272 281 8.3E-16 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HRM2_RS09975 36a804f26e1fe987f766386b69f3bf26 668 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 406 424 8.3E-16 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HRM2_RS09975 36a804f26e1fe987f766386b69f3bf26 668 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 236 247 8.3E-16 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HRM2_RS09975 36a804f26e1fe987f766386b69f3bf26 668 PANTHER PTHR10890 191 665 4.5E-110 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HRM2_RS09975 36a804f26e1fe987f766386b69f3bf26 668 Gene3D G3DSA:3.40.50.1100 1 46 1.9E-7 T 22-04-2016 HRM2_RS09975 36a804f26e1fe987f766386b69f3bf26 668 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 213 668 27.983 T 22-04-2016 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16|Reactome: REACT_71 HRM2_RS17700 335cffb006737281b18becbd3ae4c90b 460 SMART SM00849 12 183 2.1E-26 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS17700 335cffb006737281b18becbd3ae4c90b 460 PANTHER PTHR11935 1 293 1.7E-75 T 22-04-2016 HRM2_RS17700 335cffb006737281b18becbd3ae4c90b 460 PANTHER PTHR11935:SF9 1 293 1.7E-75 T 22-04-2016 HRM2_RS17700 335cffb006737281b18becbd3ae4c90b 460 Pfam PF00581 Rhodanese-like domain 258 350 1.4E-9 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS17700 335cffb006737281b18becbd3ae4c90b 460 Pfam PF00581 Rhodanese-like domain 361 452 1.3E-11 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS17700 335cffb006737281b18becbd3ae4c90b 460 SUPERFAMILY SSF56281 1 228 1.76E-45 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS17700 335cffb006737281b18becbd3ae4c90b 460 Pfam PF00753 Metallo-beta-lactamase superfamily 40 149 5.0E-8 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS17700 335cffb006737281b18becbd3ae4c90b 460 SMART SM00450 361 456 8.4E-17 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS17700 335cffb006737281b18becbd3ae4c90b 460 SMART SM00450 256 353 6.1E-5 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS17700 335cffb006737281b18becbd3ae4c90b 460 SUPERFAMILY SSF52821 253 355 3.14E-19 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS17700 335cffb006737281b18becbd3ae4c90b 460 Gene3D G3DSA:3.40.250.10 358 459 1.0E-25 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS17700 335cffb006737281b18becbd3ae4c90b 460 Gene3D G3DSA:3.40.250.10 246 354 4.4E-15 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS17700 335cffb006737281b18becbd3ae4c90b 460 SUPERFAMILY SSF52821 358 459 1.83E-26 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS17700 335cffb006737281b18becbd3ae4c90b 460 Gene3D G3DSA:3.60.15.10 4 240 1.4E-54 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS01960 1f9252c377e8610ee1fed9e73181e08a 453 TIGRFAM TIGR00416 sms: DNA repair protein RadA 4 447 2.8E-181 T 22-04-2016 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 HRM2_RS01960 1f9252c377e8610ee1fed9e73181e08a 453 SUPERFAMILY SSF52540 64 291 2.1E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01960 1f9252c377e8610ee1fed9e73181e08a 453 PANTHER PTHR32472 4 453 1.6E-206 T 22-04-2016 HRM2_RS01960 1f9252c377e8610ee1fed9e73181e08a 453 Gene3D G3DSA:3.30.230.10 281 453 3.2E-35 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HRM2_RS01960 1f9252c377e8610ee1fed9e73181e08a 453 Pfam PF06745 KaiC 70 257 5.6E-12 T 22-04-2016 IPR014774 KaiC-like domain HRM2_RS01960 1f9252c377e8610ee1fed9e73181e08a 453 SMART SM00382 87 241 4.6E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS01960 1f9252c377e8610ee1fed9e73181e08a 453 Pfam PF13541 Subunit ChlI of Mg-chelatase 343 426 6.2E-9 T 22-04-2016 HRM2_RS01960 1f9252c377e8610ee1fed9e73181e08a 453 SUPERFAMILY SSF54211 252 266 1.97E-41 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS01960 1f9252c377e8610ee1fed9e73181e08a 453 SUPERFAMILY SSF54211 300 452 1.97E-41 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS01960 1f9252c377e8610ee1fed9e73181e08a 453 PRINTS PR01874 DNA repair protein radA signature 210 238 1.7E-89 T 22-04-2016 HRM2_RS01960 1f9252c377e8610ee1fed9e73181e08a 453 PRINTS PR01874 DNA repair protein radA signature 319 342 1.7E-89 T 22-04-2016 HRM2_RS01960 1f9252c377e8610ee1fed9e73181e08a 453 PRINTS PR01874 DNA repair protein radA signature 79 107 1.7E-89 T 22-04-2016 HRM2_RS01960 1f9252c377e8610ee1fed9e73181e08a 453 PRINTS PR01874 DNA repair protein radA signature 11 35 1.7E-89 T 22-04-2016 HRM2_RS01960 1f9252c377e8610ee1fed9e73181e08a 453 PRINTS PR01874 DNA repair protein radA signature 171 195 1.7E-89 T 22-04-2016 HRM2_RS01960 1f9252c377e8610ee1fed9e73181e08a 453 PRINTS PR01874 DNA repair protein radA signature 245 271 1.7E-89 T 22-04-2016 HRM2_RS01960 1f9252c377e8610ee1fed9e73181e08a 453 PRINTS PR01874 DNA repair protein radA signature 121 138 1.7E-89 T 22-04-2016 HRM2_RS01960 1f9252c377e8610ee1fed9e73181e08a 453 Gene3D G3DSA:3.40.50.300 55 275 6.5E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17810 e1b48ac2a2cb7839d17bb0e567eaf7d2 145 SUPERFAMILY SSF52080 4 144 1.1E-46 T 22-04-2016 IPR021131 Ribosomal protein L18e/L15P HRM2_RS17810 e1b48ac2a2cb7839d17bb0e567eaf7d2 145 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 1.1E-34 T 22-04-2016 IPR021131 Ribosomal protein L18e/L15P HRM2_RS17810 e1b48ac2a2cb7839d17bb0e567eaf7d2 145 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 144 3.5E-50 T 22-04-2016 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 HRM2_RS17810 e1b48ac2a2cb7839d17bb0e567eaf7d2 145 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 22-04-2016 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17810 e1b48ac2a2cb7839d17bb0e567eaf7d2 145 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 145 20.292 T 22-04-2016 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 HRM2_RS17810 e1b48ac2a2cb7839d17bb0e567eaf7d2 145 PANTHER PTHR12934 1 145 1.1E-65 T 22-04-2016 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 HRM2_RS17810 e1b48ac2a2cb7839d17bb0e567eaf7d2 145 Gene3D G3DSA:3.100.10.10 32 145 1.1E-32 T 22-04-2016 HRM2_RS05975 e6534283964d2e782c28c437c8ad1a31 155 SUPERFAMILY SSF141371 55 144 1.41E-8 T 22-04-2016 HRM2_RS05975 e6534283964d2e782c28c437c8ad1a31 155 Gene3D G3DSA:2.40.10.220 55 141 5.2E-7 T 22-04-2016 HRM2_RS05975 e6534283964d2e782c28c437c8ad1a31 155 Pfam PF07238 PilZ domain 55 140 1.1E-8 T 22-04-2016 IPR009875 PilZ domain GO:0035438 HRM2_RS21395 445543a5d4379c181c9f5af05beba3d3 330 PRINTS PR00111 Alpha/beta hydrolase fold signature 136 149 5.1E-16 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HRM2_RS21395 445543a5d4379c181c9f5af05beba3d3 330 PRINTS PR00111 Alpha/beta hydrolase fold signature 150 163 5.1E-16 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HRM2_RS21395 445543a5d4379c181c9f5af05beba3d3 330 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 106 5.1E-16 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HRM2_RS21395 445543a5d4379c181c9f5af05beba3d3 330 PRINTS PR00111 Alpha/beta hydrolase fold signature 258 272 5.1E-16 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HRM2_RS21395 445543a5d4379c181c9f5af05beba3d3 330 PANTHER PTHR10992:SF771 293 330 2.4E-56 T 22-04-2016 HRM2_RS21395 445543a5d4379c181c9f5af05beba3d3 330 PANTHER PTHR10992:SF771 4 276 2.4E-56 T 22-04-2016 HRM2_RS21395 445543a5d4379c181c9f5af05beba3d3 330 PANTHER PTHR10992 293 330 2.4E-56 T 22-04-2016 HRM2_RS21395 445543a5d4379c181c9f5af05beba3d3 330 PANTHER PTHR10992 4 276 2.4E-56 T 22-04-2016 HRM2_RS21395 445543a5d4379c181c9f5af05beba3d3 330 Pfam PF00561 alpha/beta hydrolase fold 65 165 1.9E-24 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HRM2_RS21395 445543a5d4379c181c9f5af05beba3d3 330 SUPERFAMILY SSF53474 50 323 9.19E-52 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS21395 445543a5d4379c181c9f5af05beba3d3 330 Gene3D G3DSA:3.40.50.1820 30 325 1.2E-59 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS18330 962cb30f54954df1608f3b58f872ee9e 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 3.2E-19 T 22-04-2016 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 HRM2_RS18330 962cb30f54954df1608f3b58f872ee9e 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 3.2E-19 T 22-04-2016 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 HRM2_RS18330 962cb30f54954df1608f3b58f872ee9e 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 3.2E-19 T 22-04-2016 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 HRM2_RS18330 962cb30f54954df1608f3b58f872ee9e 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 87 1.7E-32 T 22-04-2016 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 HRM2_RS18330 962cb30f54954df1608f3b58f872ee9e 89 Pfam PF01313 Bacterial export proteins, family 3 6 78 8.7E-31 T 22-04-2016 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 HRM2_RS18330 962cb30f54954df1608f3b58f872ee9e 89 PIRSF PIRSF004669 1 89 5.7E-34 T 22-04-2016 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 HRM2_RS18330 962cb30f54954df1608f3b58f872ee9e 89 PANTHER PTHR34040:SF2 1 89 1.0E-36 T 22-04-2016 HRM2_RS18330 962cb30f54954df1608f3b58f872ee9e 89 PANTHER PTHR34040 1 89 1.0E-36 T 22-04-2016 HRM2_RS04995 7a02db1904cebd386598464b57deabf6 202 SUPERFAMILY SSF48498 82 193 1.08E-17 T 22-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal HRM2_RS04995 7a02db1904cebd386598464b57deabf6 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 6.0E-6 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS04995 7a02db1904cebd386598464b57deabf6 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 6.0E-6 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS04995 7a02db1904cebd386598464b57deabf6 202 Gene3D G3DSA:1.10.357.10 2 197 1.5E-39 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HRM2_RS04995 7a02db1904cebd386598464b57deabf6 202 SUPERFAMILY SSF46689 4 74 1.15E-16 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS04995 7a02db1904cebd386598464b57deabf6 202 Pfam PF16925 Bacterial transcriptional repressor C-terminal 100 193 9.9E-22 T 22-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal HRM2_RS04995 7a02db1904cebd386598464b57deabf6 202 PANTHER PTHR30055:SF20 1 197 3.8E-43 T 22-04-2016 HRM2_RS04995 7a02db1904cebd386598464b57deabf6 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 56 2.0E-13 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS04995 7a02db1904cebd386598464b57deabf6 202 PANTHER PTHR30055 1 197 3.8E-43 T 22-04-2016 HRM2_RS11240 2d2efc486760029f711dc1535c0837a4 390 SMART SM00388 167 240 8.9E-13 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS11240 2d2efc486760029f711dc1535c0837a4 390 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 389 4.2E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS11240 2d2efc486760029f711dc1535c0837a4 390 PRINTS PR00344 Bacterial sensor protein C-terminal signature 321 335 4.2E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS11240 2d2efc486760029f711dc1535c0837a4 390 PRINTS PR00344 Bacterial sensor protein C-terminal signature 339 349 4.2E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS11240 2d2efc486760029f711dc1535c0837a4 390 PRINTS PR00344 Bacterial sensor protein C-terminal signature 352 370 4.2E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS11240 2d2efc486760029f711dc1535c0837a4 390 Gene3D G3DSA:3.40.50.2300 15 151 4.0E-35 T 22-04-2016 HRM2_RS11240 2d2efc486760029f711dc1535c0837a4 390 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 283 389 3.5E-20 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS11240 2d2efc486760029f711dc1535c0837a4 390 Gene3D G3DSA:3.30.565.10 240 390 8.2E-39 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS11240 2d2efc486760029f711dc1535c0837a4 390 Pfam PF00072 Response regulator receiver domain 20 129 1.2E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS11240 2d2efc486760029f711dc1535c0837a4 390 PANTHER PTHR24423 2 14 2.2E-60 T 22-04-2016 HRM2_RS11240 2d2efc486760029f711dc1535c0837a4 390 PANTHER PTHR24423 134 390 2.2E-60 T 22-04-2016 HRM2_RS11240 2d2efc486760029f711dc1535c0837a4 390 SUPERFAMILY SSF52172 15 157 4.98E-39 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS11240 2d2efc486760029f711dc1535c0837a4 390 SMART SM00387 282 390 9.1E-27 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS11240 2d2efc486760029f711dc1535c0837a4 390 SUPERFAMILY SSF55874 230 390 1.83E-40 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS11240 2d2efc486760029f711dc1535c0837a4 390 SUPERFAMILY SSF47384 155 237 4.9E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS11240 2d2efc486760029f711dc1535c0837a4 390 SMART SM00448 18 129 4.1E-32 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS11240 2d2efc486760029f711dc1535c0837a4 390 Gene3D G3DSA:1.10.287.130 168 236 4.0E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS11240 2d2efc486760029f711dc1535c0837a4 390 Pfam PF00512 His Kinase A (phospho-acceptor) domain 167 238 1.9E-13 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS23495 46792bf76161e69aafff9f4ebb3f7e33 337 PANTHER PTHR33442:SF2 1 334 2.9E-134 T 22-04-2016 HRM2_RS23495 46792bf76161e69aafff9f4ebb3f7e33 337 SUPERFAMILY SSF54506 1 331 3.48E-105 T 22-04-2016 HRM2_RS23495 46792bf76161e69aafff9f4ebb3f7e33 337 PANTHER PTHR33442 1 334 2.9E-134 T 22-04-2016 HRM2_RS23495 46792bf76161e69aafff9f4ebb3f7e33 337 Gene3D G3DSA:3.10.310.10 1 157 1.1E-62 T 22-04-2016 HRM2_RS23495 46792bf76161e69aafff9f4ebb3f7e33 337 PIRSF PIRSF029792 1 334 2.1E-126 T 22-04-2016 IPR008794 Proline racemase family HRM2_RS23495 46792bf76161e69aafff9f4ebb3f7e33 337 Gene3D G3DSA:3.10.310.10 158 321 6.2E-58 T 22-04-2016 HRM2_RS23495 46792bf76161e69aafff9f4ebb3f7e33 337 Pfam PF05544 Proline racemase 10 331 7.6E-117 T 22-04-2016 IPR008794 Proline racemase family HRM2_RS21285 dfe0105bdf94540b0640fe9f9ed7a95b 547 Pfam PF04961 Formiminotransferase-cyclodeaminase 338 517 9.4E-63 T 22-04-2016 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00379 HRM2_RS21285 dfe0105bdf94540b0640fe9f9ed7a95b 547 SUPERFAMILY SSF101262 334 537 1.57E-53 T 22-04-2016 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00379 HRM2_RS21285 dfe0105bdf94540b0640fe9f9ed7a95b 547 Pfam PF07837 Formiminotransferase domain, N-terminal subdomain 4 179 8.6E-69 T 22-04-2016 IPR012886 Formiminotransferase, N-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|UniPathway: UPA00193|UniPathway: UPA00379 HRM2_RS21285 dfe0105bdf94540b0640fe9f9ed7a95b 547 SMART SM01222 3 180 6.0E-112 T 22-04-2016 IPR012886 Formiminotransferase, N-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|UniPathway: UPA00193|UniPathway: UPA00379 HRM2_RS21285 dfe0105bdf94540b0640fe9f9ed7a95b 547 PANTHER PTHR12234:SF0 1 498 2.0E-277 T 22-04-2016 HRM2_RS21285 dfe0105bdf94540b0640fe9f9ed7a95b 547 TIGRFAM TIGR02024 FtcD: glutamate formiminotransferase 1 309 2.6E-117 T 22-04-2016 IPR004227 Formiminotransferase catalytic domain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|UniPathway: UPA00193|UniPathway: UPA00379 HRM2_RS21285 dfe0105bdf94540b0640fe9f9ed7a95b 547 Pfam PF02971 Formiminotransferase domain 181 324 2.0E-61 T 22-04-2016 IPR013802 Formiminotransferase, C-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|UniPathway: UPA00193|UniPathway: UPA00379 HRM2_RS21285 dfe0105bdf94540b0640fe9f9ed7a95b 547 SUPERFAMILY SSF55116 3 179 5.89E-67 T 22-04-2016 IPR022384 Formiminotransferase subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|UniPathway: UPA00193|UniPathway: UPA00379 HRM2_RS21285 dfe0105bdf94540b0640fe9f9ed7a95b 547 Gene3D G3DSA:3.30.990.10 2 181 1.7E-72 T 22-04-2016 IPR012886 Formiminotransferase, N-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|UniPathway: UPA00193|UniPathway: UPA00379 HRM2_RS21285 dfe0105bdf94540b0640fe9f9ed7a95b 547 PANTHER PTHR12234 1 498 2.0E-277 T 22-04-2016 HRM2_RS21285 dfe0105bdf94540b0640fe9f9ed7a95b 547 SUPERFAMILY SSF55116 181 326 1.83E-50 T 22-04-2016 IPR022384 Formiminotransferase subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|UniPathway: UPA00193|UniPathway: UPA00379 HRM2_RS21285 dfe0105bdf94540b0640fe9f9ed7a95b 547 Gene3D G3DSA:3.30.70.670 182 325 1.6E-53 T 22-04-2016 IPR013802 Formiminotransferase, C-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|UniPathway: UPA00193|UniPathway: UPA00379 HRM2_RS21285 dfe0105bdf94540b0640fe9f9ed7a95b 547 SMART SM01221 181 325 2.3E-85 T 22-04-2016 IPR013802 Formiminotransferase, C-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|UniPathway: UPA00193|UniPathway: UPA00379 HRM2_RS22115 c5ef48c1112f2fdb4cfc18520b3dbe08 159 PANTHER PTHR23091:SF237 1 122 6.8E-15 T 22-04-2016 HRM2_RS22115 c5ef48c1112f2fdb4cfc18520b3dbe08 159 Pfam PF13508 Acetyltransferase (GNAT) domain 45 121 5.0E-12 T 22-04-2016 IPR000182 GNAT domain GO:0008080 HRM2_RS22115 c5ef48c1112f2fdb4cfc18520b3dbe08 159 PANTHER PTHR23091 1 122 6.8E-15 T 22-04-2016 HRM2_RS22115 c5ef48c1112f2fdb4cfc18520b3dbe08 159 SUPERFAMILY SSF55729 1 125 5.98E-21 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS22115 c5ef48c1112f2fdb4cfc18520b3dbe08 159 Gene3D G3DSA:3.40.630.30 1 137 1.8E-20 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS16435 336968f882ef9557a80c538d71865333 162 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 25 154 9.7E-24 T 22-04-2016 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component HRM2_RS16435 336968f882ef9557a80c538d71865333 162 PANTHER PTHR35011 3 154 4.5E-15 T 22-04-2016 HRM2_RS05780 6b534f561b6861c453f4bc2abcdafec6 312 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 58 213 3.6E-35 T 22-04-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 HRM2_RS05780 6b534f561b6861c453f4bc2abcdafec6 312 Gene3D G3DSA:3.40.50.700 48 229 2.0E-58 T 22-04-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 HRM2_RS05780 6b534f561b6861c453f4bc2abcdafec6 312 SUPERFAMILY SSF56770 48 310 9.08E-86 T 22-04-2016 HRM2_RS05780 6b534f561b6861c453f4bc2abcdafec6 312 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 231 309 5.5E-29 T 22-04-2016 IPR027394 Cytochrome-c3 hydrogenase, C-terminal HRM2_RS05780 6b534f561b6861c453f4bc2abcdafec6 312 PIRSF PIRSF000310 2 312 4.7E-122 T 22-04-2016 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 HRM2_RS05780 6b534f561b6861c453f4bc2abcdafec6 312 PANTHER PTHR30013 10 312 2.8E-108 T 22-04-2016 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 HRM2_RS05780 6b534f561b6861c453f4bc2abcdafec6 312 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 218 235 1.3E-40 T 22-04-2016 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 HRM2_RS05780 6b534f561b6861c453f4bc2abcdafec6 312 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 160 184 1.3E-40 T 22-04-2016 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 HRM2_RS05780 6b534f561b6861c453f4bc2abcdafec6 312 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 193 216 1.3E-40 T 22-04-2016 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 HRM2_RS05780 6b534f561b6861c453f4bc2abcdafec6 312 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 236 254 1.3E-40 T 22-04-2016 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 HRM2_RS05780 6b534f561b6861c453f4bc2abcdafec6 312 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 43 65 1.3E-40 T 22-04-2016 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 HRM2_RS05780 6b534f561b6861c453f4bc2abcdafec6 312 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 66 90 1.3E-40 T 22-04-2016 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 HRM2_RS05780 6b534f561b6861c453f4bc2abcdafec6 312 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 297 309 1.3E-40 T 22-04-2016 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 HRM2_RS05780 6b534f561b6861c453f4bc2abcdafec6 312 TIGRFAM TIGR00391 hydA: hydrogenase (NiFe) small subunit (hydA) 5 310 1.8E-80 T 22-04-2016 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 HRM2_RS05780 6b534f561b6861c453f4bc2abcdafec6 312 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 11 36 1.6E-4 T 22-04-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal HRM2_RS05780 6b534f561b6861c453f4bc2abcdafec6 312 Gene3D G3DSA:4.10.480.10 231 310 1.9E-26 T 22-04-2016 IPR027394 Cytochrome-c3 hydrogenase, C-terminal HRM2_RS10590 b7b4aee102234de499955eb8bee66e15 577 ProSitePatterns PS00455 Putative AMP-binding domain signature. 210 221 - T 22-04-2016 IPR020845 AMP-binding, conserved site HRM2_RS10590 b7b4aee102234de499955eb8bee66e15 577 PANTHER PTHR24096 25 573 1.6E-166 T 22-04-2016 HRM2_RS10590 b7b4aee102234de499955eb8bee66e15 577 Gene3D G3DSA:3.30.300.30 477 575 8.2E-32 T 22-04-2016 HRM2_RS10590 b7b4aee102234de499955eb8bee66e15 577 Gene3D G3DSA:3.40.50.980 27 214 3.2E-37 T 22-04-2016 HRM2_RS10590 b7b4aee102234de499955eb8bee66e15 577 Gene3D G3DSA:3.40.50.980 215 392 1.3E-42 T 22-04-2016 HRM2_RS10590 b7b4aee102234de499955eb8bee66e15 577 Gene3D G3DSA:2.30.38.10 393 470 5.4E-21 T 22-04-2016 HRM2_RS10590 b7b4aee102234de499955eb8bee66e15 577 Pfam PF13193 AMP-binding enzyme C-terminal domain 490 564 2.7E-17 T 22-04-2016 IPR025110 AMP-binding enzyme C-terminal domain HRM2_RS10590 b7b4aee102234de499955eb8bee66e15 577 Pfam PF00501 AMP-binding enzyme 31 480 5.1E-102 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS10590 b7b4aee102234de499955eb8bee66e15 577 SUPERFAMILY SSF56801 10 576 7.46E-148 T 22-04-2016 HRM2_RS12405 c7c763aa9b5de9581b6315b235b88a2c 288 SMART SM00729 54 262 2.0E-10 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS12405 c7c763aa9b5de9581b6315b235b88a2c 288 TIGRFAM TIGR00510 lipA: lipoyl synthase 5 287 1.1E-115 T 22-04-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 HRM2_RS12405 c7c763aa9b5de9581b6315b235b88a2c 288 Gene3D G3DSA:3.20.20.70 21 284 2.2E-66 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS12405 c7c763aa9b5de9581b6315b235b88a2c 288 Pfam PF04055 Radical SAM superfamily 62 222 9.7E-9 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS12405 c7c763aa9b5de9581b6315b235b88a2c 288 PANTHER PTHR10949 8 288 4.7E-141 T 22-04-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 HRM2_RS12405 c7c763aa9b5de9581b6315b235b88a2c 288 PIRSF PIRSF005963 1 288 3.5E-126 T 22-04-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 HRM2_RS12405 c7c763aa9b5de9581b6315b235b88a2c 288 SUPERFAMILY SSF102114 19 279 1.24E-60 T 22-04-2016 HRM2_RS12405 c7c763aa9b5de9581b6315b235b88a2c 288 Hamap MF_00206 Lipoyl synthase [lipA]. 1 288 137.877 T 22-04-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 HRM2_RS12405 c7c763aa9b5de9581b6315b235b88a2c 288 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 9 43 5.3E-7 T 22-04-2016 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 HRM2_RS13180 5834420e0c4657c1ee5509ce504d16ca 423 Pfam PF00994 Probable molybdopterin binding domain 5 168 1.3E-29 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS13180 5834420e0c4657c1ee5509ce504d16ca 423 Gene3D G3DSA:3.40.980.10 1 212 2.7E-30 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS13180 5834420e0c4657c1ee5509ce504d16ca 423 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 269 411 9.6E-41 T 22-04-2016 IPR008136 CinA, C-terminal HRM2_RS13180 5834420e0c4657c1ee5509ce504d16ca 423 PANTHER PTHR13939 1 423 2.4E-148 T 22-04-2016 HRM2_RS13180 5834420e0c4657c1ee5509ce504d16ca 423 PIRSF PIRSF006728 1 421 6.2E-121 T 22-04-2016 IPR008135 Competence-induced protein CinA HRM2_RS13180 5834420e0c4657c1ee5509ce504d16ca 423 SUPERFAMILY SSF142433 257 416 4.71E-54 T 22-04-2016 IPR008136 CinA, C-terminal HRM2_RS13180 5834420e0c4657c1ee5509ce504d16ca 423 Gene3D G3DSA:3.90.950.20 257 416 9.3E-56 T 22-04-2016 IPR008136 CinA, C-terminal HRM2_RS13180 5834420e0c4657c1ee5509ce504d16ca 423 Pfam PF02464 Competence-damaged protein 263 415 5.4E-55 T 22-04-2016 IPR008136 CinA, C-terminal HRM2_RS13180 5834420e0c4657c1ee5509ce504d16ca 423 SUPERFAMILY SSF53218 1 211 1.83E-38 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS13180 5834420e0c4657c1ee5509ce504d16ca 423 SMART SM00852 4 170 8.1E-37 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS13180 5834420e0c4657c1ee5509ce504d16ca 423 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 423 139.413 T 22-04-2016 IPR008135 Competence-induced protein CinA HRM2_RS13180 5834420e0c4657c1ee5509ce504d16ca 423 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 1 166 2.3E-25 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS13180 5834420e0c4657c1ee5509ce504d16ca 423 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 416 5.7E-92 T 22-04-2016 IPR008135 Competence-induced protein CinA HRM2_RS11580 80e1b17db55eebfff4865f4a85e81de4 663 SUPERFAMILY SSF52540 3 414 5.73E-132 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11580 80e1b17db55eebfff4865f4a85e81de4 663 Gene3D G3DSA:3.40.50.300 277 337 3.1E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11580 80e1b17db55eebfff4865f4a85e81de4 663 Gene3D G3DSA:3.40.50.300 6 88 3.1E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11580 80e1b17db55eebfff4865f4a85e81de4 663 Gene3D G3DSA:3.40.50.300 387 406 3.1E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11580 80e1b17db55eebfff4865f4a85e81de4 663 Pfam PF00271 Helicase conserved C-terminal domain 431 544 1.3E-19 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS11580 80e1b17db55eebfff4865f4a85e81de4 663 PANTHER PTHR24029 1 663 0.0 T 22-04-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 HRM2_RS11580 80e1b17db55eebfff4865f4a85e81de4 663 Gene3D G3DSA:3.30.2060.10 158 230 5.3E-11 T 22-04-2016 HRM2_RS11580 80e1b17db55eebfff4865f4a85e81de4 663 Pfam PF02151 UvrB/uvrC motif 626 659 1.7E-7 T 22-04-2016 IPR001943 UVR domain GO:0005515 HRM2_RS11580 80e1b17db55eebfff4865f4a85e81de4 663 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 3 657 0.0 T 22-04-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 HRM2_RS11580 80e1b17db55eebfff4865f4a85e81de4 663 SMART SM00490 459 545 4.0E-19 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS11580 80e1b17db55eebfff4865f4a85e81de4 663 Hamap MF_00204 UvrABC system protein B [uvrB]. 2 660 42.303 T 22-04-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 HRM2_RS11580 80e1b17db55eebfff4865f4a85e81de4 663 SUPERFAMILY SSF52540 469 592 6.49E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11580 80e1b17db55eebfff4865f4a85e81de4 663 SUPERFAMILY SSF52540 31 79 6.49E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11580 80e1b17db55eebfff4865f4a85e81de4 663 SUPERFAMILY SSF46600 619 661 4.05E-10 T 22-04-2016 IPR001943 UVR domain GO:0005515 HRM2_RS11580 80e1b17db55eebfff4865f4a85e81de4 663 Gene3D G3DSA:4.10.860.10 621 662 1.5E-12 T 22-04-2016 IPR001943 UVR domain GO:0005515 HRM2_RS11580 80e1b17db55eebfff4865f4a85e81de4 663 Pfam PF12344 Ultra-violet resistance protein B 551 593 4.2E-21 T 22-04-2016 IPR024759 UvrB, YAD/RRR-motif-containing domain HRM2_RS11580 80e1b17db55eebfff4865f4a85e81de4 663 SMART SM00487 8 425 1.2E-26 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS11580 80e1b17db55eebfff4865f4a85e81de4 663 Gene3D G3DSA:3.40.50.300 420 581 2.2E-39 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11580 80e1b17db55eebfff4865f4a85e81de4 663 Pfam PF04851 Type III restriction enzyme, res subunit 13 130 2.0E-10 T 22-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HRM2_RS08905 4b14954254759417e0144fed182cbf02 163 Gene3D G3DSA:3.40.50.620 27 147 1.8E-33 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS08905 4b14954254759417e0144fed182cbf02 163 Pfam PF01467 Cytidylyltransferase-like 32 156 2.5E-15 T 22-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HRM2_RS08905 4b14954254759417e0144fed182cbf02 163 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 29 94 1.3E-16 T 22-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HRM2_RS08905 4b14954254759417e0144fed182cbf02 163 PANTHER PTHR10739:SF26 16 162 1.2E-43 T 22-04-2016 HRM2_RS08905 4b14954254759417e0144fed182cbf02 163 PANTHER PTHR10739 16 162 1.2E-43 T 22-04-2016 HRM2_RS08905 4b14954254759417e0144fed182cbf02 163 SUPERFAMILY SSF52374 27 158 1.93E-25 T 22-04-2016 HRM2_RS08905 4b14954254759417e0144fed182cbf02 163 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 18 159 5.1E-57 T 22-04-2016 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167|UniPathway: UPA00356|UniPathway: UPA00356 HRM2_RS23190 5d570c1ff9a69f0432c87f500fba1521 273 SUPERFAMILY SSF58104 9 271 5.58E-57 T 22-04-2016 HRM2_RS23190 5d570c1ff9a69f0432c87f500fba1521 273 Gene3D G3DSA:1.10.287.950 18 228 1.7E-49 T 22-04-2016 HRM2_RS23190 5d570c1ff9a69f0432c87f500fba1521 273 SMART SM00283 10 271 2.9E-47 T 22-04-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HRM2_RS23190 5d570c1ff9a69f0432c87f500fba1521 273 PANTHER PTHR32089 1 273 8.5E-63 T 22-04-2016 HRM2_RS23190 5d570c1ff9a69f0432c87f500fba1521 273 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 24 53 3.9E-22 T 22-04-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HRM2_RS23190 5d570c1ff9a69f0432c87f500fba1521 273 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 130 159 3.9E-22 T 22-04-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HRM2_RS23190 5d570c1ff9a69f0432c87f500fba1521 273 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 178 207 3.9E-22 T 22-04-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HRM2_RS23190 5d570c1ff9a69f0432c87f500fba1521 273 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 101 128 3.9E-22 T 22-04-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HRM2_RS23190 5d570c1ff9a69f0432c87f500fba1521 273 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 73 270 3.1E-37 T 22-04-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HRM2_RS16585 9b3e7805273753b75f70446d4233d5a3 402 Pfam PF13565 Homeodomain-like domain 56 132 2.2E-10 T 22-04-2016 HRM2_RS16585 9b3e7805273753b75f70446d4233d5a3 402 PANTHER PTHR24559 160 272 4.1E-12 T 22-04-2016 HRM2_RS16585 9b3e7805273753b75f70446d4233d5a3 402 Gene3D G3DSA:3.30.420.10 150 311 1.3E-37 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS16585 9b3e7805273753b75f70446d4233d5a3 402 SUPERFAMILY SSF46689 52 132 3.4E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS16585 9b3e7805273753b75f70446d4233d5a3 402 Pfam PF00665 Integrase core domain 159 273 4.0E-23 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 HRM2_RS16585 9b3e7805273753b75f70446d4233d5a3 402 SUPERFAMILY SSF53098 153 316 7.84E-30 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS18165 9b3e7805273753b75f70446d4233d5a3 402 Pfam PF13565 Homeodomain-like domain 56 132 2.2E-10 T 22-04-2016 HRM2_RS18165 9b3e7805273753b75f70446d4233d5a3 402 PANTHER PTHR24559 160 272 4.1E-12 T 22-04-2016 HRM2_RS18165 9b3e7805273753b75f70446d4233d5a3 402 Gene3D G3DSA:3.30.420.10 150 311 1.3E-37 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS18165 9b3e7805273753b75f70446d4233d5a3 402 SUPERFAMILY SSF46689 52 132 3.4E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS18165 9b3e7805273753b75f70446d4233d5a3 402 Pfam PF00665 Integrase core domain 159 273 4.0E-23 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 HRM2_RS18165 9b3e7805273753b75f70446d4233d5a3 402 SUPERFAMILY SSF53098 153 316 7.84E-30 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS16480 7f2190882b414c615d407b8d6ce471f4 368 SMART SM00471 177 314 2.9E-6 T 22-04-2016 IPR003607 HD/PDEase domain HRM2_RS16480 7f2190882b414c615d407b8d6ce471f4 368 SUPERFAMILY SSF109604 163 343 7.54E-38 T 22-04-2016 HRM2_RS16480 7f2190882b414c615d407b8d6ce471f4 368 Gene3D G3DSA:1.10.3210.10 160 342 1.7E-20 T 22-04-2016 IPR006674 HD domain HRM2_RS16480 7f2190882b414c615d407b8d6ce471f4 368 PANTHER PTHR26402 270 309 1.4E-47 T 22-04-2016 HRM2_RS16480 7f2190882b414c615d407b8d6ce471f4 368 PANTHER PTHR26402 8 139 1.4E-47 T 22-04-2016 HRM2_RS16480 7f2190882b414c615d407b8d6ce471f4 368 SMART SM00448 8 121 5.8E-45 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS16480 7f2190882b414c615d407b8d6ce471f4 368 Pfam PF00072 Response regulator receiver domain 10 122 1.0E-32 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS16480 7f2190882b414c615d407b8d6ce471f4 368 PANTHER PTHR26402:SF495 270 309 1.4E-47 T 22-04-2016 HRM2_RS16480 7f2190882b414c615d407b8d6ce471f4 368 PANTHER PTHR26402:SF495 8 139 1.4E-47 T 22-04-2016 HRM2_RS16480 7f2190882b414c615d407b8d6ce471f4 368 SUPERFAMILY SSF52172 6 170 1.85E-45 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS16480 7f2190882b414c615d407b8d6ce471f4 368 Gene3D G3DSA:3.40.50.2300 7 133 4.8E-47 T 22-04-2016 HRM2_RS16480 7f2190882b414c615d407b8d6ce471f4 368 Pfam PF13487 HD domain 232 295 2.1E-16 T 22-04-2016 HRM2_RS20920 b6fe5d909adecf13e7625906be6012fb 293 Gene3D G3DSA:3.30.70.20 58 102 2.6E-14 T 22-04-2016 HRM2_RS20920 b6fe5d909adecf13e7625906be6012fb 293 SUPERFAMILY SSF52540 140 281 5.77E-33 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20920 b6fe5d909adecf13e7625906be6012fb 293 SUPERFAMILY SSF52540 1 46 5.77E-33 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20920 b6fe5d909adecf13e7625906be6012fb 293 PANTHER PTHR13696 1 293 8.8E-79 T 22-04-2016 HRM2_RS20920 b6fe5d909adecf13e7625906be6012fb 293 SUPERFAMILY SSF54862 61 191 6.4E-19 T 22-04-2016 HRM2_RS20920 b6fe5d909adecf13e7625906be6012fb 293 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 252 8.5E-30 T 22-04-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain HRM2_RS20920 b6fe5d909adecf13e7625906be6012fb 293 PANTHER PTHR13696:SF37 1 293 8.8E-79 T 22-04-2016 HRM2_RS20920 b6fe5d909adecf13e7625906be6012fb 293 Gene3D G3DSA:3.40.50.300 1 53 4.6E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20920 b6fe5d909adecf13e7625906be6012fb 293 Gene3D G3DSA:3.40.50.300 103 281 4.6E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20920 b6fe5d909adecf13e7625906be6012fb 293 Pfam PF00037 4Fe-4S binding domain 62 84 1.6E-4 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS20920 b6fe5d909adecf13e7625906be6012fb 293 Pfam PF00037 4Fe-4S binding domain 88 110 4.6E-6 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS20920 b6fe5d909adecf13e7625906be6012fb 293 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 94 105 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS02450 56778fec58840f34247988d6194ecc5c 378 Gene3D G3DSA:3.40.50.2300 26 223 1.1E-53 T 22-04-2016 HRM2_RS02450 56778fec58840f34247988d6194ecc5c 378 PANTHER PTHR30483:SF6 7 375 6.5E-67 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HRM2_RS02450 56778fec58840f34247988d6194ecc5c 378 SUPERFAMILY SSF53822 26 373 5.72E-80 T 22-04-2016 IPR028082 Periplasmic binding protein-like I HRM2_RS02450 56778fec58840f34247988d6194ecc5c 378 PANTHER PTHR30483 7 375 6.5E-67 T 22-04-2016 HRM2_RS02450 56778fec58840f34247988d6194ecc5c 378 Pfam PF13458 Periplasmic binding protein 27 368 1.0E-61 T 22-04-2016 IPR028081 Leucine-binding protein domain HRM2_RS02450 56778fec58840f34247988d6194ecc5c 378 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 90 100 3.4E-6 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HRM2_RS02450 56778fec58840f34247988d6194ecc5c 378 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 28 44 3.4E-6 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HRM2_RS02450 56778fec58840f34247988d6194ecc5c 378 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 50 66 3.4E-6 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HRM2_RS02450 56778fec58840f34247988d6194ecc5c 378 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 255 273 3.4E-6 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HRM2_RS09215 124eb6ca64ef98239a1e970a9ee47e2c 410 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 21 399 2.3E-102 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 HRM2_RS09215 124eb6ca64ef98239a1e970a9ee47e2c 410 Gene3D G3DSA:3.40.718.10 8 404 3.0E-144 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 HRM2_RS09215 124eb6ca64ef98239a1e970a9ee47e2c 410 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 291 310 - T 22-04-2016 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 HRM2_RS09215 124eb6ca64ef98239a1e970a9ee47e2c 410 SMART SM01329 20 400 1.6E-166 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 HRM2_RS09215 124eb6ca64ef98239a1e970a9ee47e2c 410 PANTHER PTHR11835 263 410 4.1E-189 T 22-04-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 HRM2_RS09215 124eb6ca64ef98239a1e970a9ee47e2c 410 PANTHER PTHR11835 175 241 4.1E-189 T 22-04-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 HRM2_RS09215 124eb6ca64ef98239a1e970a9ee47e2c 410 PANTHER PTHR11835 3 154 4.1E-189 T 22-04-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 HRM2_RS09215 124eb6ca64ef98239a1e970a9ee47e2c 410 PANTHER PTHR11835:SF52 263 410 4.1E-189 T 22-04-2016 HRM2_RS09215 124eb6ca64ef98239a1e970a9ee47e2c 410 PANTHER PTHR11835:SF52 175 241 4.1E-189 T 22-04-2016 HRM2_RS09215 124eb6ca64ef98239a1e970a9ee47e2c 410 PANTHER PTHR11835:SF52 3 154 4.1E-189 T 22-04-2016 HRM2_RS09215 124eb6ca64ef98239a1e970a9ee47e2c 410 SUPERFAMILY SSF53659 11 404 7.68E-128 T 22-04-2016 HRM2_RS13775 0f48c887cc9b885f80f6edcf2ef58508 179 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 16 167 3.0E-53 T 22-04-2016 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 HRM2_RS13775 0f48c887cc9b885f80f6edcf2ef58508 179 PANTHER PTHR21485:SF3 7 179 1.1E-44 T 22-04-2016 HRM2_RS13775 0f48c887cc9b885f80f6edcf2ef58508 179 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 17 133 1.8E-12 T 22-04-2016 IPR006549 HAD-superfamily hydrolase,subfamily IIIA HRM2_RS13775 0f48c887cc9b885f80f6edcf2ef58508 179 Pfam PF08282 haloacid dehalogenase-like hydrolase 91 154 2.8E-12 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS13775 0f48c887cc9b885f80f6edcf2ef58508 179 PANTHER PTHR21485 7 179 1.1E-44 T 22-04-2016 HRM2_RS13775 0f48c887cc9b885f80f6edcf2ef58508 179 PIRSF PIRSF006118 3 178 9.5E-66 T 22-04-2016 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 HRM2_RS13775 0f48c887cc9b885f80f6edcf2ef58508 179 SUPERFAMILY SSF56784 13 174 1.84E-43 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS13775 0f48c887cc9b885f80f6edcf2ef58508 179 Gene3D G3DSA:3.40.50.1000 11 173 7.9E-44 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS15875 067cf0de94e2075754910ad1f331bd20 627 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 22-04-2016 IPR020595 MnmG-related, conserved site HRM2_RS15875 067cf0de94e2075754910ad1f331bd20 627 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 8 618 5.1E-243 T 22-04-2016 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 HRM2_RS15875 067cf0de94e2075754910ad1f331bd20 627 PANTHER PTHR11806 4 624 0.0 T 22-04-2016 HRM2_RS15875 067cf0de94e2075754910ad1f331bd20 627 PANTHER PTHR11806:SF0 4 624 0.0 T 22-04-2016 HRM2_RS15875 067cf0de94e2075754910ad1f331bd20 627 SMART SM01228 545 616 1.8E-40 T 22-04-2016 HRM2_RS15875 067cf0de94e2075754910ad1f331bd20 627 Pfam PF01134 Glucose inhibited division protein A 9 398 1.1E-149 T 22-04-2016 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 HRM2_RS15875 067cf0de94e2075754910ad1f331bd20 627 Gene3D G3DSA:3.50.50.60 8 231 6.3E-31 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS15875 067cf0de94e2075754910ad1f331bd20 627 SUPERFAMILY SSF51905 6 69 3.4E-34 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS15875 067cf0de94e2075754910ad1f331bd20 627 SUPERFAMILY SSF51905 100 260 3.4E-34 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS15875 067cf0de94e2075754910ad1f331bd20 627 Pfam PF13932 GidA associated domain 401 614 6.3E-66 T 22-04-2016 IPR026904 GidA associated domain 3 HRM2_RS15875 067cf0de94e2075754910ad1f331bd20 627 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 6 623 38.822 T 22-04-2016 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 HRM2_RS15875 067cf0de94e2075754910ad1f331bd20 627 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 1.1E-6 T 22-04-2016 HRM2_RS15875 067cf0de94e2075754910ad1f331bd20 627 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 161 1.1E-6 T 22-04-2016 HRM2_RS13565 64f2face293957d18d820811b4c453fe 360 PANTHER PTHR33376:SF5 1 338 1.6E-72 T 22-04-2016 HRM2_RS13565 64f2face293957d18d820811b4c453fe 360 PIRSF PIRSF039026 1 349 1.6E-90 T 22-04-2016 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like HRM2_RS13565 64f2face293957d18d820811b4c453fe 360 Gene3D G3DSA:3.40.190.10 154 210 2.2E-4 T 22-04-2016 HRM2_RS13565 64f2face293957d18d820811b4c453fe 360 SUPERFAMILY SSF53850 145 262 1.36E-6 T 22-04-2016 HRM2_RS13565 64f2face293957d18d820811b4c453fe 360 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 35 318 3.8E-38 T 22-04-2016 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 HRM2_RS13565 64f2face293957d18d820811b4c453fe 360 PANTHER PTHR33376 1 338 1.6E-72 T 22-04-2016 HRM2_RS01250 6e832d2bbb66b940147eadec555c0a84 273 Gene3D G3DSA:1.10.3210.10 58 195 1.1E-11 T 22-04-2016 IPR006674 HD domain HRM2_RS01250 6e832d2bbb66b940147eadec555c0a84 273 SUPERFAMILY SSF109604 44 247 1.5E-15 T 22-04-2016 HRM2_RS25475 c10b007150d2d0aa8079de21ba780508 71 Gene3D G3DSA:1.20.5.1030 14 70 2.0E-22 T 22-04-2016 HRM2_RS25475 c10b007150d2d0aa8079de21ba780508 71 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 16 70 2.8E-20 T 22-04-2016 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 HRM2_RS25475 c10b007150d2d0aa8079de21ba780508 71 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 18 46 - T 22-04-2016 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 HRM2_RS25475 c10b007150d2d0aa8079de21ba780508 71 PANTHER PTHR33910:SF1 14 71 5.2E-15 T 22-04-2016 HRM2_RS25475 c10b007150d2d0aa8079de21ba780508 71 PANTHER PTHR33910 14 71 5.2E-15 T 22-04-2016 HRM2_RS25475 c10b007150d2d0aa8079de21ba780508 71 Hamap MF_00422 Protein translocase subunit SecE [secE]. 13 68 12.55 T 22-04-2016 IPR022943 Preprotein translocase subunit SecE HRM2_RS25475 c10b007150d2d0aa8079de21ba780508 71 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 17 68 3.6E-22 T 22-04-2016 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 HRM2_RS00970 cfa36056dbe6aa39fa8ee1e4c8513e4c 143 PANTHER PTHR24960:SF48 4 103 5.3E-12 T 22-04-2016 HRM2_RS00970 cfa36056dbe6aa39fa8ee1e4c8513e4c 143 SUPERFAMILY SSF54862 4 55 9.42E-17 T 22-04-2016 HRM2_RS00970 cfa36056dbe6aa39fa8ee1e4c8513e4c 143 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 39 50 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS00970 cfa36056dbe6aa39fa8ee1e4c8513e4c 143 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS00970 cfa36056dbe6aa39fa8ee1e4c8513e4c 143 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 80 91 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS00970 cfa36056dbe6aa39fa8ee1e4c8513e4c 143 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 117 128 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS00970 cfa36056dbe6aa39fa8ee1e4c8513e4c 143 Gene3D G3DSA:3.30.70.20 91 136 3.3E-15 T 22-04-2016 HRM2_RS00970 cfa36056dbe6aa39fa8ee1e4c8513e4c 143 PANTHER PTHR24960 4 103 5.3E-12 T 22-04-2016 HRM2_RS00970 cfa36056dbe6aa39fa8ee1e4c8513e4c 143 Gene3D G3DSA:3.30.70.20 3 44 3.4E-15 T 22-04-2016 HRM2_RS00970 cfa36056dbe6aa39fa8ee1e4c8513e4c 143 SUPERFAMILY SSF54862 72 140 3.07E-17 T 22-04-2016 HRM2_RS00970 cfa36056dbe6aa39fa8ee1e4c8513e4c 143 Gene3D G3DSA:3.30.70.20 45 90 2.1E-12 T 22-04-2016 HRM2_RS00970 cfa36056dbe6aa39fa8ee1e4c8513e4c 143 Pfam PF12838 4Fe-4S dicluster domain 79 131 3.3E-9 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS00970 cfa36056dbe6aa39fa8ee1e4c8513e4c 143 Pfam PF12838 4Fe-4S dicluster domain 8 52 7.3E-11 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS06850 c339712cc61ac07b4c2674505ea79b68 604 SUPERFAMILY SSF160246 62 181 2.75E-20 T 22-04-2016 HRM2_RS06850 c339712cc61ac07b4c2674505ea79b68 604 Gene3D G3DSA:3.40.50.300 333 602 3.6E-92 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06850 c339712cc61ac07b4c2674505ea79b68 604 Pfam PF00437 Type II/IV secretion system protein 233 494 2.8E-72 T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 HRM2_RS06850 c339712cc61ac07b4c2674505ea79b68 604 PANTHER PTHR30258:SF13 14 602 1.2E-182 T 22-04-2016 HRM2_RS06850 c339712cc61ac07b4c2674505ea79b68 604 Gene3D G3DSA:3.30.450.90 203 327 9.9E-46 T 22-04-2016 HRM2_RS06850 c339712cc61ac07b4c2674505ea79b68 604 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 84 184 1.2E-20 T 22-04-2016 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 HRM2_RS06850 c339712cc61ac07b4c2674505ea79b68 604 PANTHER PTHR30258 14 602 1.2E-182 T 22-04-2016 HRM2_RS06850 c339712cc61ac07b4c2674505ea79b68 604 SUPERFAMILY SSF52540 219 602 2.0E-97 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06850 c339712cc61ac07b4c2674505ea79b68 604 SMART SM00382 355 476 2.6E-4 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS06850 c339712cc61ac07b4c2674505ea79b68 604 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 422 436 - T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 HRM2_RS17865 44fe32ff486b9c5bc4096206a70122f2 135 Gene3D G3DSA:3.90.1170.10 23 134 7.5E-51 T 22-04-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17865 44fe32ff486b9c5bc4096206a70122f2 135 SUPERFAMILY SSF54686 1 134 6.54E-54 T 22-04-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17865 44fe32ff486b9c5bc4096206a70122f2 135 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 126 9.6E-56 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 HRM2_RS17865 44fe32ff486b9c5bc4096206a70122f2 135 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 7.7E-48 T 22-04-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17865 44fe32ff486b9c5bc4096206a70122f2 135 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.4E-36 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 HRM2_RS17865 44fe32ff486b9c5bc4096206a70122f2 135 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.4E-36 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 HRM2_RS17865 44fe32ff486b9c5bc4096206a70122f2 135 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.4E-36 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 HRM2_RS17865 44fe32ff486b9c5bc4096206a70122f2 135 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.4E-36 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 HRM2_RS17865 44fe32ff486b9c5bc4096206a70122f2 135 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 22-04-2016 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17865 44fe32ff486b9c5bc4096206a70122f2 135 PANTHER PTHR12220 1 135 3.0E-65 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 HRM2_RS17865 44fe32ff486b9c5bc4096206a70122f2 135 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 38.134 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 HRM2_RS04010 dce62bcc58ac8aa764f15eb756156cca 117 SUPERFAMILY SSF48008 5 87 1.67E-7 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS04010 dce62bcc58ac8aa764f15eb756156cca 117 Pfam PF07729 FCD domain 4 84 1.4E-6 T 22-04-2016 IPR011711 GntR, C-terminal HRM2_RS04010 dce62bcc58ac8aa764f15eb756156cca 117 Gene3D G3DSA:1.20.120.530 8 85 2.3E-7 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS05890 8b271db30be4be3b919ced342bd9a4ef 609 SUPERFAMILY SSF109604 325 561 5.23E-59 T 22-04-2016 HRM2_RS05890 8b271db30be4be3b919ced342bd9a4ef 609 Gene3D G3DSA:1.10.3150.10 325 595 8.7E-74 T 22-04-2016 IPR013976 Metal-dependent hydrolase HDOD HRM2_RS05890 8b271db30be4be3b919ced342bd9a4ef 609 PANTHER PTHR33525 330 551 6.1E-56 T 22-04-2016 HRM2_RS05890 8b271db30be4be3b919ced342bd9a4ef 609 Pfam PF08668 HDOD domain 336 532 1.6E-54 T 22-04-2016 IPR013976 Metal-dependent hydrolase HDOD HRM2_RS05890 8b271db30be4be3b919ced342bd9a4ef 609 PANTHER PTHR33525:SF3 330 551 6.1E-56 T 22-04-2016 HRM2_RS16645 a803e3386abaeec34ec0e2556b7299cc 121 Pfam PF04343 Protein of unknown function, DUF488 9 117 3.3E-29 T 22-04-2016 IPR007438 Protein of unknown function DUF488 HRM2_RS16645 a803e3386abaeec34ec0e2556b7299cc 121 PANTHER PTHR36849 5 121 5.9E-45 T 22-04-2016 HRM2_RS16645 a803e3386abaeec34ec0e2556b7299cc 121 PANTHER PTHR36849:SF1 5 121 5.9E-45 T 22-04-2016 HRM2_RS14580 ea134e9cfceb556c2da5e6445fe10677 332 Gene3D G3DSA:3.40.50.410 83 286 5.6E-31 T 22-04-2016 IPR002035 von Willebrand factor, type A HRM2_RS14580 ea134e9cfceb556c2da5e6445fe10677 332 SMART SM00327 86 266 3.8E-19 T 22-04-2016 IPR002035 von Willebrand factor, type A HRM2_RS14580 ea134e9cfceb556c2da5e6445fe10677 332 PANTHER PTHR22550:SF12 64 330 7.1E-66 T 22-04-2016 HRM2_RS14580 ea134e9cfceb556c2da5e6445fe10677 332 SUPERFAMILY SSF53300 83 268 5.79E-38 T 22-04-2016 IPR002035 von Willebrand factor, type A HRM2_RS14580 ea134e9cfceb556c2da5e6445fe10677 332 Pfam PF00092 von Willebrand factor type A domain 88 284 3.2E-29 T 22-04-2016 IPR002035 von Willebrand factor, type A HRM2_RS14580 ea134e9cfceb556c2da5e6445fe10677 332 Pfam PF07584 Aerotolerance regulator N-terminal 1 73 4.4E-7 T 22-04-2016 IPR024163 Aerotolerance regulator, N-terminal HRM2_RS14580 ea134e9cfceb556c2da5e6445fe10677 332 PANTHER PTHR22550 64 330 7.1E-66 T 22-04-2016 HRM2_RS19080 f1051b30b4ac638d33c9e6ddf253cd42 253 Pfam PF01144 Coenzyme A transferase 7 217 8.6E-26 T 22-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 HRM2_RS19080 f1051b30b4ac638d33c9e6ddf253cd42 253 SUPERFAMILY SSF100950 1 251 1.6E-58 T 22-04-2016 HRM2_RS19080 f1051b30b4ac638d33c9e6ddf253cd42 253 SMART SM00882 7 218 4.2E-10 T 22-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 HRM2_RS19080 f1051b30b4ac638d33c9e6ddf253cd42 253 Gene3D G3DSA:3.40.810.20 1 252 2.4E-79 T 22-04-2016 HRM2_RS19080 f1051b30b4ac638d33c9e6ddf253cd42 253 PANTHER PTHR13707:SF35 1 237 2.0E-48 T 22-04-2016 HRM2_RS19080 f1051b30b4ac638d33c9e6ddf253cd42 253 PANTHER PTHR13707 1 237 2.0E-48 T 22-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 Pfam PF07977 FabA-like domain 1708 1842 1.6E-30 T 22-04-2016 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 SMART SM00825 Beta-ketoacyl synthase 8 435 1.4E-64 T 22-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 SUPERFAMILY SSF54637 1467 1641 2.09E-20 T 22-04-2016 IPR029069 HotDog domain HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 Gene3D G3DSA:3.40.47.10 762 903 3.4E-21 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 Gene3D G3DSA:3.40.47.10 283 436 5.2E-44 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 PANTHER PTHR11712:SF279 918 1127 7.4E-146 T 22-04-2016 HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 PANTHER PTHR11712:SF279 1143 1360 7.4E-146 T 22-04-2016 HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 PANTHER PTHR11712:SF279 6 455 7.4E-146 T 22-04-2016 HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 SUPERFAMILY SSF53901 453 716 2.02E-37 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 173 189 - T 22-04-2016 IPR018201 Beta-ketoacyl synthase, active site HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 SUPERFAMILY SSF53901 156 377 1.44E-61 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 SUPERFAMILY SSF53901 410 429 1.44E-61 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 Gene3D G3DSA:3.40.366.10 1017 1120 1.1E-17 T 22-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 Gene3D G3DSA:3.40.366.10 1203 1308 1.1E-17 T 22-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6 260 7.4E-51 T 22-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 453 712 2.6E-32 T 22-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 SUPERFAMILY SSF53901 682 904 9.6E-31 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 392 460 3.6E-8 T 22-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 Pfam PF00698 Acyl transferase domain 1077 1292 1.0E-6 T 22-04-2016 IPR014043 Acyl transferase HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 SUPERFAMILY SSF54637 1675 1846 1.11E-29 T 22-04-2016 IPR029069 HotDog domain HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 SUPERFAMILY SSF52151 1204 1307 9.42E-31 T 22-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 SUPERFAMILY SSF52151 1020 1126 9.42E-31 T 22-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 Gene3D G3DSA:3.10.129.10 1465 1642 1.9E-23 T 22-04-2016 IPR029069 HotDog domain HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 Gene3D G3DSA:3.10.129.10 1670 1851 1.2E-45 T 22-04-2016 IPR029069 HotDog domain HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 269 384 3.6E-31 T 22-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 763 850 9.9E-13 T 22-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1024 1313 4.0E-10 T 22-04-2016 IPR020801 Polyketide synthase, acyl transferase domain HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 PANTHER PTHR11712 918 1127 7.4E-146 T 22-04-2016 HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 PANTHER PTHR11712 1143 1360 7.4E-146 T 22-04-2016 HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 PANTHER PTHR11712 6 455 7.4E-146 T 22-04-2016 HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 SUPERFAMILY SSF53901 5 128 1.44E-61 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 Gene3D G3DSA:3.40.47.10 4 273 3.3E-63 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS11675 2def25be7521da6bbe8ee66f15515dbb 1864 Gene3D G3DSA:3.40.47.10 448 725 7.2E-44 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS14295 e8bf7c386ead04759689d5e90d346885 325 TIGRFAM TIGR00452 TIGR00452: tRNA (mo5U34)-methyltransferase 33 323 2.8E-125 T 22-04-2016 IPR010017 tRNA (mo5U34)-methyltransferase GO:0002098|GO:0016300 HRM2_RS14295 e8bf7c386ead04759689d5e90d346885 325 Hamap MF_01590 tRNA (mo5U34)-methyltransferase [cmoB]. 2 324 45.525 T 22-04-2016 IPR010017 tRNA (mo5U34)-methyltransferase GO:0002098|GO:0016300 HRM2_RS14295 e8bf7c386ead04759689d5e90d346885 325 PANTHER PTHR10108:SF847 1 324 1.6E-68 T 22-04-2016 HRM2_RS14295 e8bf7c386ead04759689d5e90d346885 325 Gene3D G3DSA:3.40.50.150 106 314 1.3E-17 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS14295 e8bf7c386ead04759689d5e90d346885 325 SUPERFAMILY SSF53335 90 318 8.52E-24 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS14295 e8bf7c386ead04759689d5e90d346885 325 Pfam PF08003 Protein of unknown function (DUF1698) 27 323 7.5E-108 T 22-04-2016 IPR027555 tRNA (mo5U34)-methyltransferase-like HRM2_RS14295 e8bf7c386ead04759689d5e90d346885 325 PANTHER PTHR10108 1 324 1.6E-68 T 22-04-2016 HRM2_RS11895 c8e4997bdef3eff7e94df783a1758647 895 Pfam PF05188 MutS domain II 127 261 1.7E-18 T 22-04-2016 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 HRM2_RS11895 c8e4997bdef3eff7e94df783a1758647 895 Gene3D G3DSA:3.40.50.300 583 818 6.3E-83 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11895 c8e4997bdef3eff7e94df783a1758647 895 Gene3D G3DSA:3.30.420.110 125 265 2.1E-33 T 22-04-2016 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 HRM2_RS11895 c8e4997bdef3eff7e94df783a1758647 895 PANTHER PTHR11361:SF86 1 895 0.0 T 22-04-2016 HRM2_RS11895 c8e4997bdef3eff7e94df783a1758647 895 SMART SM00533 294 607 4.6E-101 T 22-04-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 HRM2_RS11895 c8e4997bdef3eff7e94df783a1758647 895 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 7 887 1.2E-295 T 22-04-2016 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 HRM2_RS11895 c8e4997bdef3eff7e94df783a1758647 895 Pfam PF05190 MutS family domain IV 444 535 2.4E-28 T 22-04-2016 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 HRM2_RS11895 c8e4997bdef3eff7e94df783a1758647 895 SUPERFAMILY SSF52540 583 818 5.42E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11895 c8e4997bdef3eff7e94df783a1758647 895 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 6 881 24.504 T 22-04-2016 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 HRM2_RS11895 c8e4997bdef3eff7e94df783a1758647 895 SUPERFAMILY SSF53150 113 276 2.88E-33 T 22-04-2016 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 HRM2_RS11895 c8e4997bdef3eff7e94df783a1758647 895 SUPERFAMILY SSF55271 4 112 1.57E-41 T 22-04-2016 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 HRM2_RS11895 c8e4997bdef3eff7e94df783a1758647 895 Gene3D G3DSA:1.10.1420.10 273 484 2.0E-49 T 22-04-2016 HRM2_RS11895 c8e4997bdef3eff7e94df783a1758647 895 Pfam PF05192 MutS domain III 280 575 6.2E-39 T 22-04-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 HRM2_RS11895 c8e4997bdef3eff7e94df783a1758647 895 PANTHER PTHR11361 1 895 0.0 T 22-04-2016 HRM2_RS11895 c8e4997bdef3eff7e94df783a1758647 895 SMART SM00534 625 814 4.1E-108 T 22-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 HRM2_RS11895 c8e4997bdef3eff7e94df783a1758647 895 Pfam PF01624 MutS domain I 7 118 3.5E-42 T 22-04-2016 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 HRM2_RS11895 c8e4997bdef3eff7e94df783a1758647 895 PIRSF PIRSF037677 1 891 1.1E-168 T 22-04-2016 HRM2_RS11895 c8e4997bdef3eff7e94df783a1758647 895 SUPERFAMILY SSF48334 277 582 1.31E-81 T 22-04-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 HRM2_RS11895 c8e4997bdef3eff7e94df783a1758647 895 Pfam PF00488 MutS domain V 628 816 3.8E-81 T 22-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 HRM2_RS11895 c8e4997bdef3eff7e94df783a1758647 895 Gene3D G3DSA:3.40.1170.10 3 119 8.4E-49 T 22-04-2016 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 HRM2_RS11895 c8e4997bdef3eff7e94df783a1758647 895 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 706 722 - T 22-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 HRM2_RS11565 f7cc6134afabeae1cdde3e8df97c24c7 163 SUPERFAMILY SSF69765 1 156 1.44E-63 T 22-04-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 HRM2_RS11565 f7cc6134afabeae1cdde3e8df97c24c7 163 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2 155 1.2E-62 T 22-04-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 HRM2_RS11565 f7cc6134afabeae1cdde3e8df97c24c7 163 PANTHER PTHR32125 2 159 1.9E-49 T 22-04-2016 HRM2_RS11565 f7cc6134afabeae1cdde3e8df97c24c7 163 Gene3D G3DSA:3.30.1330.50 1 157 1.8E-67 T 22-04-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 HRM2_RS11565 f7cc6134afabeae1cdde3e8df97c24c7 163 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 1 156 36.007 T 22-04-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 HRM2_RS11565 f7cc6134afabeae1cdde3e8df97c24c7 163 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 35 50 - T 22-04-2016 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 HRM2_RS11565 f7cc6134afabeae1cdde3e8df97c24c7 163 Pfam PF02542 YgbB family 2 154 2.4E-63 T 22-04-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 HRM2_RS12850 7cbdbbeb582724263b4d6e8965c97379 772 Pfam PF13426 PAS domain 295 391 0.037 T 22-04-2016 IPR000014 PAS domain HRM2_RS12850 7cbdbbeb582724263b4d6e8965c97379 772 Pfam PF13426 PAS domain 416 513 1.4E-11 T 22-04-2016 IPR000014 PAS domain HRM2_RS12850 7cbdbbeb582724263b4d6e8965c97379 772 PRINTS PR00344 Bacterial sensor protein C-terminal signature 708 718 3.0E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS12850 7cbdbbeb582724263b4d6e8965c97379 772 PRINTS PR00344 Bacterial sensor protein C-terminal signature 690 704 3.0E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS12850 7cbdbbeb582724263b4d6e8965c97379 772 PRINTS PR00344 Bacterial sensor protein C-terminal signature 721 739 3.0E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS12850 7cbdbbeb582724263b4d6e8965c97379 772 PRINTS PR00344 Bacterial sensor protein C-terminal signature 745 758 3.0E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS12850 7cbdbbeb582724263b4d6e8965c97379 772 SUPERFAMILY SSF55785 274 391 5.06E-8 T 22-04-2016 IPR000014 PAS domain HRM2_RS12850 7cbdbbeb582724263b4d6e8965c97379 772 SUPERFAMILY SSF47384 525 597 5.3E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS12850 7cbdbbeb582724263b4d6e8965c97379 772 Gene3D G3DSA:3.30.565.10 601 759 6.9E-41 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS12850 7cbdbbeb582724263b4d6e8965c97379 772 SMART SM00388 529 600 5.2E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS12850 7cbdbbeb582724263b4d6e8965c97379 772 SMART SM00091 405 473 6.3E-8 T 22-04-2016 IPR000014 PAS domain HRM2_RS12850 7cbdbbeb582724263b4d6e8965c97379 772 Gene3D G3DSA:3.30.450.20 371 402 2.0E-6 T 22-04-2016 HRM2_RS12850 7cbdbbeb582724263b4d6e8965c97379 772 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 642 759 5.1E-17 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS12850 7cbdbbeb582724263b4d6e8965c97379 772 Gene3D G3DSA:1.10.287.130 526 596 4.7E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS12850 7cbdbbeb582724263b4d6e8965c97379 772 SUPERFAMILY SSF55785 390 512 3.77E-18 T 22-04-2016 IPR000014 PAS domain HRM2_RS12850 7cbdbbeb582724263b4d6e8965c97379 772 SMART SM00304 224 276 7.6E-7 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS12850 7cbdbbeb582724263b4d6e8965c97379 772 SMART SM00387 642 761 7.9E-25 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS12850 7cbdbbeb582724263b4d6e8965c97379 772 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 403 519 3.5E-9 T 22-04-2016 IPR000014 PAS domain HRM2_RS12850 7cbdbbeb582724263b4d6e8965c97379 772 Gene3D G3DSA:3.30.450.20 274 370 9.0E-6 T 22-04-2016 HRM2_RS12850 7cbdbbeb582724263b4d6e8965c97379 772 SUPERFAMILY SSF158472 226 273 1.02E-5 T 22-04-2016 HRM2_RS12850 7cbdbbeb582724263b4d6e8965c97379 772 Pfam PF00512 His Kinase A (phospho-acceptor) domain 530 597 7.2E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS12850 7cbdbbeb582724263b4d6e8965c97379 772 PANTHER PTHR24423 340 772 5.8E-91 T 22-04-2016 HRM2_RS12850 7cbdbbeb582724263b4d6e8965c97379 772 SUPERFAMILY SSF55874 589 763 4.58E-39 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS12850 7cbdbbeb582724263b4d6e8965c97379 772 Gene3D G3DSA:3.30.450.20 403 512 1.5E-18 T 22-04-2016 HRM2_RS12850 7cbdbbeb582724263b4d6e8965c97379 772 Pfam PF00672 HAMP domain 205 273 5.4E-10 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS06800 950fd06bf3bc29262270bbe2f107bd39 557 Pfam PF00501 AMP-binding enzyme 35 465 1.7E-107 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS06800 950fd06bf3bc29262270bbe2f107bd39 557 SUPERFAMILY SSF56801 20 557 6.28E-154 T 22-04-2016 HRM2_RS06800 950fd06bf3bc29262270bbe2f107bd39 557 PANTHER PTHR24096 31 165 6.4E-179 T 22-04-2016 HRM2_RS06800 950fd06bf3bc29262270bbe2f107bd39 557 PANTHER PTHR24096 183 557 6.4E-179 T 22-04-2016 HRM2_RS06800 950fd06bf3bc29262270bbe2f107bd39 557 ProSitePatterns PS00455 Putative AMP-binding domain signature. 215 226 - T 22-04-2016 IPR020845 AMP-binding, conserved site HRM2_RS06800 950fd06bf3bc29262270bbe2f107bd39 557 Gene3D G3DSA:3.30.300.30 460 557 2.1E-30 T 22-04-2016 HRM2_RS06800 950fd06bf3bc29262270bbe2f107bd39 557 Pfam PF13193 AMP-binding enzyme C-terminal domain 475 549 8.3E-19 T 22-04-2016 IPR025110 AMP-binding enzyme C-terminal domain HRM2_RS06800 950fd06bf3bc29262270bbe2f107bd39 557 Gene3D G3DSA:3.40.50.980 221 380 1.9E-44 T 22-04-2016 HRM2_RS06800 950fd06bf3bc29262270bbe2f107bd39 557 Gene3D G3DSA:3.40.50.980 189 220 3.1E-38 T 22-04-2016 HRM2_RS06800 950fd06bf3bc29262270bbe2f107bd39 557 Gene3D G3DSA:3.40.50.980 31 157 3.1E-38 T 22-04-2016 HRM2_RS06800 950fd06bf3bc29262270bbe2f107bd39 557 Gene3D G3DSA:2.30.38.10 381 456 4.9E-31 T 22-04-2016 HRM2_RS07110 ff862006d3b33c7dbef35cff222d8b0c 557 SMART SM00387 454 552 5.2E-12 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS07110 ff862006d3b33c7dbef35cff222d8b0c 557 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 458 550 2.8E-11 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS07110 ff862006d3b33c7dbef35cff222d8b0c 557 SMART SM00065 180 329 0.0037 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS07110 ff862006d3b33c7dbef35cff222d8b0c 557 PANTHER PTHR24421 315 549 7.2E-40 T 22-04-2016 HRM2_RS07110 ff862006d3b33c7dbef35cff222d8b0c 557 Pfam PF07730 Histidine kinase 349 415 3.5E-12 T 22-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 HRM2_RS07110 ff862006d3b33c7dbef35cff222d8b0c 557 SUPERFAMILY SSF55781 184 321 3.05E-14 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS07110 ff862006d3b33c7dbef35cff222d8b0c 557 Pfam PF01590 GAF domain 185 319 4.1E-7 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS07110 ff862006d3b33c7dbef35cff222d8b0c 557 Gene3D G3DSA:3.30.450.40 161 335 1.2E-29 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS07110 ff862006d3b33c7dbef35cff222d8b0c 557 Gene3D G3DSA:3.30.565.10 438 549 2.3E-12 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS07110 ff862006d3b33c7dbef35cff222d8b0c 557 SUPERFAMILY SSF55874 424 549 6.81E-20 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS07110 ff862006d3b33c7dbef35cff222d8b0c 557 Gene3D G3DSA:3.30.450.20 42 160 6.9E-5 T 22-04-2016 HRM2_RS07110 ff862006d3b33c7dbef35cff222d8b0c 557 SUPERFAMILY SSF55785 42 154 5.23E-5 T 22-04-2016 IPR000014 PAS domain HRM2_RS07110 ff862006d3b33c7dbef35cff222d8b0c 557 PANTHER PTHR24421:SF18 315 549 7.2E-40 T 22-04-2016 HRM2_RS22015 fee1a8b2a4ddfd493adaee128516201f 482 SUPERFAMILY SSF53098 175 307 1.39E-23 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS22015 fee1a8b2a4ddfd493adaee128516201f 482 Gene3D G3DSA:3.30.420.10 176 338 1.1E-27 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS22015 fee1a8b2a4ddfd493adaee128516201f 482 Pfam PF00665 Integrase core domain 183 296 3.9E-17 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 HRM2_RS09575 fee1a8b2a4ddfd493adaee128516201f 482 SUPERFAMILY SSF53098 175 307 1.39E-23 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS09575 fee1a8b2a4ddfd493adaee128516201f 482 Gene3D G3DSA:3.30.420.10 176 338 1.1E-27 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS09575 fee1a8b2a4ddfd493adaee128516201f 482 Pfam PF00665 Integrase core domain 183 296 3.9E-17 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 HRM2_RS14025 c963fd3d467d12e77945c685cc68b9fc 175 Pfam PF14803 Nudix N-terminal 3 34 6.6E-13 T 22-04-2016 IPR029401 Nudix hydrolase, N-terminal KEGG: 00230+3.6.1.-+3.6.1.13|KEGG: 00332+3.6.1.-|KEGG: 00740+3.6.1.18|KEGG: 00790+3.6.1.- HRM2_RS14025 c963fd3d467d12e77945c685cc68b9fc 175 Pfam PF00293 NUDIX domain 41 143 1.5E-14 T 22-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 HRM2_RS14025 c963fd3d467d12e77945c685cc68b9fc 175 Gene3D G3DSA:2.20.70.10 1 34 1.2E-13 T 22-04-2016 HRM2_RS14025 c963fd3d467d12e77945c685cc68b9fc 175 PANTHER PTHR22769 1 167 2.3E-60 T 22-04-2016 HRM2_RS14025 c963fd3d467d12e77945c685cc68b9fc 175 SUPERFAMILY SSF55811 2 163 2.57E-37 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HRM2_RS14025 c963fd3d467d12e77945c685cc68b9fc 175 PANTHER PTHR22769:SF17 1 167 2.3E-60 T 22-04-2016 HRM2_RS14025 c963fd3d467d12e77945c685cc68b9fc 175 Gene3D G3DSA:3.90.79.10 36 171 5.1E-33 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HRM2_RS20340 7bc8ac5867f3bfebb6c562f3dad0d9d5 113 PANTHER PTHR33495 1 113 3.5E-26 T 22-04-2016 HRM2_RS20340 7bc8ac5867f3bfebb6c562f3dad0d9d5 113 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 104 2.2E-24 T 22-04-2016 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 HRM2_RS20340 7bc8ac5867f3bfebb6c562f3dad0d9d5 113 SUPERFAMILY SSF52091 1 108 2.75E-25 T 22-04-2016 IPR002645 STAS domain HRM2_RS20340 7bc8ac5867f3bfebb6c562f3dad0d9d5 113 Pfam PF01740 STAS domain 6 106 2.5E-17 T 22-04-2016 IPR002645 STAS domain HRM2_RS20340 7bc8ac5867f3bfebb6c562f3dad0d9d5 113 Gene3D G3DSA:3.30.750.24 2 110 2.1E-29 T 22-04-2016 IPR002645 STAS domain HRM2_RS06820 773ca6421b9f307a4e8f57577dc4f5c1 212 Gene3D G3DSA:3.40.50.2300 1 121 1.1E-35 T 22-04-2016 HRM2_RS06820 773ca6421b9f307a4e8f57577dc4f5c1 212 SUPERFAMILY SSF46894 132 210 8.84E-20 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HRM2_RS06820 773ca6421b9f307a4e8f57577dc4f5c1 212 PANTHER PTHR26402 2 208 9.1E-67 T 22-04-2016 HRM2_RS06820 773ca6421b9f307a4e8f57577dc4f5c1 212 Gene3D G3DSA:1.10.10.10 122 211 5.8E-24 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS06820 773ca6421b9f307a4e8f57577dc4f5c1 212 SUPERFAMILY SSF52172 1 128 2.13E-35 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS06820 773ca6421b9f307a4e8f57577dc4f5c1 212 SMART SM00421 147 204 4.2E-18 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS06820 773ca6421b9f307a4e8f57577dc4f5c1 212 SMART SM00448 2 115 6.9E-32 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS06820 773ca6421b9f307a4e8f57577dc4f5c1 212 Pfam PF00072 Response regulator receiver domain 4 116 5.3E-32 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS06820 773ca6421b9f307a4e8f57577dc4f5c1 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 204 6.5E-18 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS06820 773ca6421b9f307a4e8f57577dc4f5c1 212 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS06820 773ca6421b9f307a4e8f57577dc4f5c1 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 1.2E-10 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS06820 773ca6421b9f307a4e8f57577dc4f5c1 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 1.2E-10 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS06820 773ca6421b9f307a4e8f57577dc4f5c1 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 1.2E-10 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS06820 773ca6421b9f307a4e8f57577dc4f5c1 212 PANTHER PTHR26402:SF151 2 208 9.1E-67 T 22-04-2016 HRM2_RS09485 0f1f8ceebf79d5c23bb21d8fd3e0d5f3 386 Pfam PF00589 Phage integrase family 184 358 2.9E-15 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS09485 0f1f8ceebf79d5c23bb21d8fd3e0d5f3 386 PANTHER PTHR30349 79 359 6.5E-28 T 22-04-2016 HRM2_RS09485 0f1f8ceebf79d5c23bb21d8fd3e0d5f3 386 PANTHER PTHR30349:SF20 79 359 6.5E-28 T 22-04-2016 HRM2_RS09485 0f1f8ceebf79d5c23bb21d8fd3e0d5f3 386 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 77 132 2.1E-9 T 22-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 HRM2_RS09485 0f1f8ceebf79d5c23bb21d8fd3e0d5f3 386 SUPERFAMILY SSF56349 77 359 2.83E-54 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HRM2_RS09485 0f1f8ceebf79d5c23bb21d8fd3e0d5f3 386 Gene3D G3DSA:1.10.150.130 77 172 3.8E-13 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal HRM2_RS09485 0f1f8ceebf79d5c23bb21d8fd3e0d5f3 386 Gene3D G3DSA:1.10.443.10 178 358 1.3E-30 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS05365 d3e35a481e4b4136fcadcf30633538cd 278 PANTHER PTHR30071 13 273 9.4E-58 T 22-04-2016 HRM2_RS05365 d3e35a481e4b4136fcadcf30633538cd 278 Pfam PF01578 Cytochrome C assembly protein 75 271 1.5E-39 T 22-04-2016 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 HRM2_RS05365 d3e35a481e4b4136fcadcf30633538cd 278 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 46 273 2.5E-56 T 22-04-2016 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 HRM2_RS05365 d3e35a481e4b4136fcadcf30633538cd 278 PANTHER PTHR30071:SF5 13 273 9.4E-58 T 22-04-2016 HRM2_RS04460 991f66b2486fbd7bba570712bcfb151b 257 Gene3D G3DSA:3.60.110.10 4 253 1.4E-61 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 HRM2_RS04460 991f66b2486fbd7bba570712bcfb151b 257 PANTHER PTHR23088 5 254 6.3E-97 T 22-04-2016 HRM2_RS04460 991f66b2486fbd7bba570712bcfb151b 257 Pfam PF00795 Carbon-nitrogen hydrolase 7 222 5.5E-28 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 HRM2_RS04460 991f66b2486fbd7bba570712bcfb151b 257 SUPERFAMILY SSF56317 4 251 1.01E-62 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 HRM2_RS04460 991f66b2486fbd7bba570712bcfb151b 257 PANTHER PTHR23088:SF28 5 254 6.3E-97 T 22-04-2016 HRM2_RS02225 12135650bc92e920c75d3fa1f2538cd7 653 TIGRFAM TIGR02061 aprA: adenylylsulfate reductase, alpha subunit 25 651 3.1E-281 T 22-04-2016 IPR011803 Adenylylsulphate reductase, alpha subunit KEGG: 00920+1.8.99.2|MetaCyc: PWY-5278|MetaCyc: PWY-5279 HRM2_RS02225 12135650bc92e920c75d3fa1f2538cd7 653 SUPERFAMILY SSF51905 432 501 1.17E-61 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS02225 12135650bc92e920c75d3fa1f2538cd7 653 SUPERFAMILY SSF51905 17 287 1.17E-61 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS02225 12135650bc92e920c75d3fa1f2538cd7 653 Pfam PF00890 FAD binding domain 25 271 1.8E-11 T 22-04-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain HRM2_RS02225 12135650bc92e920c75d3fa1f2538cd7 653 Gene3D G3DSA:3.50.50.60 180 270 1.4E-31 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS02225 12135650bc92e920c75d3fa1f2538cd7 653 Gene3D G3DSA:3.50.50.60 20 134 1.4E-31 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS02225 12135650bc92e920c75d3fa1f2538cd7 653 Gene3D G3DSA:3.50.50.60 431 478 1.4E-31 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS02225 12135650bc92e920c75d3fa1f2538cd7 653 PIRSF PIRSF000171 14 653 3.4E-243 T 22-04-2016 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit HRM2_RS02225 12135650bc92e920c75d3fa1f2538cd7 653 SUPERFAMILY SSF56425 269 416 7.43E-63 T 22-04-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain HRM2_RS02225 12135650bc92e920c75d3fa1f2538cd7 653 SUPERFAMILY SSF46977 519 650 1.44E-33 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 HRM2_RS02225 12135650bc92e920c75d3fa1f2538cd7 653 Gene3D G3DSA:3.90.700.10 274 408 6.7E-64 T 22-04-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain HRM2_RS02225 12135650bc92e920c75d3fa1f2538cd7 653 PANTHER PTHR11632:SF57 17 653 9.4E-219 T 22-04-2016 HRM2_RS02225 12135650bc92e920c75d3fa1f2538cd7 653 PANTHER PTHR11632 17 653 9.4E-219 T 22-04-2016 HRM2_RS02225 12135650bc92e920c75d3fa1f2538cd7 653 Gene3D G3DSA:1.20.58.100 501 617 1.1E-36 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 HRM2_RS01240 a4e7d5dbce5407abfd3e6076b4444646 596 Gene3D G3DSA:3.30.1360.30 288 421 2.9E-47 T 22-04-2016 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 HRM2_RS01240 a4e7d5dbce5407abfd3e6076b4444646 596 Pfam PF00152 tRNA synthetases class II (D, K and N) 129 566 3.4E-110 T 22-04-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS01240 a4e7d5dbce5407abfd3e6076b4444646 596 PANTHER PTHR22594 8 308 1.5E-250 T 22-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS01240 a4e7d5dbce5407abfd3e6076b4444646 596 PANTHER PTHR22594 377 579 1.5E-250 T 22-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS01240 a4e7d5dbce5407abfd3e6076b4444646 596 PANTHER PTHR22594:SF5 8 308 1.5E-250 T 22-04-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 HRM2_RS01240 a4e7d5dbce5407abfd3e6076b4444646 596 PANTHER PTHR22594:SF5 377 579 1.5E-250 T 22-04-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 HRM2_RS01240 a4e7d5dbce5407abfd3e6076b4444646 596 PRINTS PR01042 Aspartyl-tRNA synthetase signature 201 213 8.5E-24 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS01240 a4e7d5dbce5407abfd3e6076b4444646 596 PRINTS PR01042 Aspartyl-tRNA synthetase signature 218 231 8.5E-24 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS01240 a4e7d5dbce5407abfd3e6076b4444646 596 PRINTS PR01042 Aspartyl-tRNA synthetase signature 526 540 8.5E-24 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS01240 a4e7d5dbce5407abfd3e6076b4444646 596 PRINTS PR01042 Aspartyl-tRNA synthetase signature 482 498 8.5E-24 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS01240 a4e7d5dbce5407abfd3e6076b4444646 596 Gene3D G3DSA:3.30.930.10 142 287 7.7E-114 T 22-04-2016 HRM2_RS01240 a4e7d5dbce5407abfd3e6076b4444646 596 Gene3D G3DSA:3.30.930.10 422 592 7.7E-114 T 22-04-2016 HRM2_RS01240 a4e7d5dbce5407abfd3e6076b4444646 596 Hamap MF_00044 Aspartate--tRNA(Asp) ligase [aspS]. 9 571 35.793 T 22-04-2016 HRM2_RS01240 a4e7d5dbce5407abfd3e6076b4444646 596 SUPERFAMILY SSF55681 432 592 1.47E-105 T 22-04-2016 HRM2_RS01240 a4e7d5dbce5407abfd3e6076b4444646 596 SUPERFAMILY SSF55681 125 303 1.47E-105 T 22-04-2016 HRM2_RS01240 a4e7d5dbce5407abfd3e6076b4444646 596 Gene3D G3DSA:2.40.50.140 9 117 3.5E-38 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS01240 a4e7d5dbce5407abfd3e6076b4444646 596 SUPERFAMILY SSF50249 10 114 1.2E-31 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS01240 a4e7d5dbce5407abfd3e6076b4444646 596 Pfam PF02938 GAD domain 319 413 1.2E-26 T 22-04-2016 IPR029351 GAD domain HRM2_RS01240 a4e7d5dbce5407abfd3e6076b4444646 596 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 8 592 1.2E-241 T 22-04-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 HRM2_RS01240 a4e7d5dbce5407abfd3e6076b4444646 596 Pfam PF01336 OB-fold nucleic acid binding domain 26 111 3.3E-15 T 22-04-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 HRM2_RS01240 a4e7d5dbce5407abfd3e6076b4444646 596 SUPERFAMILY SSF55261 300 427 1.5E-44 T 22-04-2016 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 HRM2_RS11795 8e04abb80eecbb80e2a28a44af732e6f 166 SUPERFAMILY SSF52833 1 163 2.78E-39 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS11795 8e04abb80eecbb80e2a28a44af732e6f 166 ProSitePatterns PS01265 Tpx family signature. 83 94 - T 22-04-2016 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 HRM2_RS11795 8e04abb80eecbb80e2a28a44af732e6f 166 PANTHER PTHR10681:SF81 5 166 8.6E-46 T 22-04-2016 HRM2_RS11795 8e04abb80eecbb80e2a28a44af732e6f 166 PANTHER PTHR10681 5 166 8.6E-46 T 22-04-2016 HRM2_RS11795 8e04abb80eecbb80e2a28a44af732e6f 166 Hamap MF_00269 Probable thiol peroxidase [tpx]. 3 166 35.809 T 22-04-2016 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 HRM2_RS11795 8e04abb80eecbb80e2a28a44af732e6f 166 Pfam PF08534 Redoxin 22 162 7.0E-25 T 22-04-2016 IPR013740 Redoxin GO:0016491 HRM2_RS11795 8e04abb80eecbb80e2a28a44af732e6f 166 Gene3D G3DSA:3.40.30.10 3 166 2.2E-43 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS05815 14f24c456e3617c9dace65fedb23516f 440 PANTHER PTHR10799 310 439 3.8E-27 T 22-04-2016 HRM2_RS05815 14f24c456e3617c9dace65fedb23516f 440 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 274 438 3.5E-52 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS05815 14f24c456e3617c9dace65fedb23516f 440 SUPERFAMILY SSF55785 164 276 6.46E-8 T 22-04-2016 IPR000014 PAS domain HRM2_RS05815 14f24c456e3617c9dace65fedb23516f 440 Pfam PF00990 Diguanylate cyclase, GGDEF domain 278 436 1.5E-46 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS05815 14f24c456e3617c9dace65fedb23516f 440 Gene3D G3DSA:3.30.70.270 280 439 3.1E-52 T 22-04-2016 HRM2_RS05815 14f24c456e3617c9dace65fedb23516f 440 Gene3D G3DSA:3.30.450.20 151 277 4.4E-13 T 22-04-2016 HRM2_RS05815 14f24c456e3617c9dace65fedb23516f 440 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 150 274 2.7E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS05815 14f24c456e3617c9dace65fedb23516f 440 SUPERFAMILY SSF55073 283 439 5.57E-47 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS05815 14f24c456e3617c9dace65fedb23516f 440 SMART SM00267 267 440 8.1E-56 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS06480 889303abd228ecbb8843435092568aab 248 Gene3D G3DSA:3.40.50.1110 39 229 2.1E-19 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain HRM2_RS06480 889303abd228ecbb8843435092568aab 248 SUPERFAMILY SSF52266 43 231 6.26E-27 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain HRM2_RS06480 889303abd228ecbb8843435092568aab 248 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 51 219 1.5E-13 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain HRM2_RS00030 387ae356f4eb50b2fd0b45ff5f1bc15c 192 PANTHER PTHR30625 1 177 1.4E-29 T 22-04-2016 HRM2_RS00030 387ae356f4eb50b2fd0b45ff5f1bc15c 192 Pfam PF01618 MotA/TolQ/ExbB proton channel family 86 177 2.0E-24 T 22-04-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 HRM2_RS23265 a94123cb5960aa6a1fbe1ca33f186e88 335 Pfam PF00891 O-methyltransferase 98 314 1.8E-29 T 22-04-2016 IPR001077 O-methyltransferase, family 2 GO:0008171 HRM2_RS23265 a94123cb5960aa6a1fbe1ca33f186e88 335 PIRSF PIRSF005739 7 327 3.1E-22 T 22-04-2016 IPR016461 O-methyltransferase COMT-type GO:0008168 HRM2_RS23265 a94123cb5960aa6a1fbe1ca33f186e88 335 SUPERFAMILY SSF46785 10 88 1.46E-11 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS23265 a94123cb5960aa6a1fbe1ca33f186e88 335 PANTHER PTHR11746 11 317 8.8E-58 T 22-04-2016 HRM2_RS23265 a94123cb5960aa6a1fbe1ca33f186e88 335 PANTHER PTHR11746:SF63 11 317 8.8E-58 T 22-04-2016 HRM2_RS23265 a94123cb5960aa6a1fbe1ca33f186e88 335 Pfam PF16864 Dimerisation domain 10 92 1.3E-15 T 22-04-2016 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain HRM2_RS23265 a94123cb5960aa6a1fbe1ca33f186e88 335 SUPERFAMILY SSF53335 94 322 5.52E-43 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS23265 a94123cb5960aa6a1fbe1ca33f186e88 335 Gene3D G3DSA:3.40.50.150 91 324 7.6E-47 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS23265 a94123cb5960aa6a1fbe1ca33f186e88 335 Gene3D G3DSA:1.10.10.10 5 84 7.0E-27 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS12720 06ad23c2caa61bc4a80aa0f936ee1149 727 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 536 707 2.2E-13 T 22-04-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain HRM2_RS12720 06ad23c2caa61bc4a80aa0f936ee1149 727 PANTHER PTHR32309 128 727 5.2E-142 T 22-04-2016 HRM2_RS12720 06ad23c2caa61bc4a80aa0f936ee1149 727 PANTHER PTHR32309 1 110 5.2E-142 T 22-04-2016 HRM2_RS12720 06ad23c2caa61bc4a80aa0f936ee1149 727 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 514 715 5.4E-55 T 22-04-2016 IPR005702 Exopolysaccharide synthesis protein GO:0045226 HRM2_RS12720 06ad23c2caa61bc4a80aa0f936ee1149 727 SUPERFAMILY SSF52540 532 716 1.21E-36 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12720 06ad23c2caa61bc4a80aa0f936ee1149 727 Gene3D G3DSA:3.40.50.300 533 711 5.1E-36 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12720 06ad23c2caa61bc4a80aa0f936ee1149 727 PANTHER PTHR32309:SF13 128 727 5.2E-142 T 22-04-2016 HRM2_RS12720 06ad23c2caa61bc4a80aa0f936ee1149 727 PANTHER PTHR32309:SF13 1 110 5.2E-142 T 22-04-2016 HRM2_RS12720 06ad23c2caa61bc4a80aa0f936ee1149 727 Pfam PF13807 G-rich domain on putative tyrosine kinase 394 464 6.2E-13 T 22-04-2016 IPR032807 Tyrosine kinase, G-rich domain HRM2_RS12720 06ad23c2caa61bc4a80aa0f936ee1149 727 Pfam PF02706 Chain length determinant protein 5 197 1.4E-15 T 22-04-2016 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 HRM2_RS05580 e27ce63bd8858593acc63708f535b28c 564 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 46 145 9.0E-9 T 22-04-2016 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 HRM2_RS05580 e27ce63bd8858593acc63708f535b28c 564 Pfam PF00437 Type II/IV secretion system protein 190 454 3.4E-80 T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 HRM2_RS05580 e27ce63bd8858593acc63708f535b28c 564 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 382 396 - T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 HRM2_RS05580 e27ce63bd8858593acc63708f535b28c 564 PANTHER PTHR30258:SF2 1 564 2.3E-199 T 22-04-2016 HRM2_RS05580 e27ce63bd8858593acc63708f535b28c 564 SUPERFAMILY SSF160246 3 142 1.65E-16 T 22-04-2016 HRM2_RS05580 e27ce63bd8858593acc63708f535b28c 564 Gene3D G3DSA:3.30.450.90 163 287 3.6E-50 T 22-04-2016 HRM2_RS05580 e27ce63bd8858593acc63708f535b28c 564 TIGRFAM TIGR02533 type_II_gspE: type II secretion system protein E 78 562 5.2E-199 T 22-04-2016 IPR013369 Type II secretion system GspE GO:0005524|GO:0008565|GO:0015627|GO:0015628 HRM2_RS05580 e27ce63bd8858593acc63708f535b28c 564 SUPERFAMILY SSF52540 170 562 6.29E-98 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05580 e27ce63bd8858593acc63708f535b28c 564 PANTHER PTHR30258 1 564 2.3E-199 T 22-04-2016 HRM2_RS05580 e27ce63bd8858593acc63708f535b28c 564 Gene3D G3DSA:3.40.50.300 292 562 6.6E-98 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05580 e27ce63bd8858593acc63708f535b28c 564 SMART SM00382 315 438 6.0E-4 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS09390 1180b4b16c20c0c61cab9bf07ca6ed4b 370 PANTHER PTHR21666:SF219 66 353 5.3E-61 T 22-04-2016 HRM2_RS09390 1180b4b16c20c0c61cab9bf07ca6ed4b 370 Pfam PF01464 Transglycosylase SLT domain 102 200 7.1E-20 T 22-04-2016 IPR008258 Transglycosylase SLT domain 1 HRM2_RS09390 1180b4b16c20c0c61cab9bf07ca6ed4b 370 Gene3D G3DSA:1.10.530.10 87 241 6.5E-38 T 22-04-2016 HRM2_RS09390 1180b4b16c20c0c61cab9bf07ca6ed4b 370 Gene3D G3DSA:3.10.350.10 322 366 9.9E-13 T 22-04-2016 IPR018392 LysM domain HRM2_RS09390 1180b4b16c20c0c61cab9bf07ca6ed4b 370 SUPERFAMILY SSF53955 91 240 1.91E-33 T 22-04-2016 IPR023346 Lysozyme-like domain HRM2_RS09390 1180b4b16c20c0c61cab9bf07ca6ed4b 370 SUPERFAMILY SSF54106 322 366 3.14E-8 T 22-04-2016 IPR018392 LysM domain HRM2_RS09390 1180b4b16c20c0c61cab9bf07ca6ed4b 370 PANTHER PTHR21666 66 353 5.3E-61 T 22-04-2016 HRM2_RS09390 1180b4b16c20c0c61cab9bf07ca6ed4b 370 SMART SM00257 323 367 6.1E-10 T 22-04-2016 IPR018392 LysM domain HRM2_RS09390 1180b4b16c20c0c61cab9bf07ca6ed4b 370 Pfam PF01476 LysM domain 324 366 5.4E-9 T 22-04-2016 IPR018392 LysM domain HRM2_RS04320 6434a1c2bfb8bc0d615f7361dc5c3720 470 SUPERFAMILY SSF51971 145 399 3.0E-66 T 22-04-2016 HRM2_RS04320 6434a1c2bfb8bc0d615f7361dc5c3720 470 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 147 455 5.0E-32 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS04320 6434a1c2bfb8bc0d615f7361dc5c3720 470 Gene3D G3DSA:3.50.50.60 392 468 4.6E-11 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS04320 6434a1c2bfb8bc0d615f7361dc5c3720 470 SUPERFAMILY SSF46548 9 156 2.2E-38 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS04320 6434a1c2bfb8bc0d615f7361dc5c3720 470 PANTHER PTHR11938 11 468 1.2E-147 T 22-04-2016 HRM2_RS04320 6434a1c2bfb8bc0d615f7361dc5c3720 470 PRINTS PR00419 Adrenodoxin reductase family signature 148 170 1.9E-16 T 22-04-2016 HRM2_RS04320 6434a1c2bfb8bc0d615f7361dc5c3720 470 PRINTS PR00419 Adrenodoxin reductase family signature 171 184 1.9E-16 T 22-04-2016 HRM2_RS04320 6434a1c2bfb8bc0d615f7361dc5c3720 470 PRINTS PR00419 Adrenodoxin reductase family signature 289 303 1.9E-16 T 22-04-2016 HRM2_RS04320 6434a1c2bfb8bc0d615f7361dc5c3720 470 PRINTS PR00419 Adrenodoxin reductase family signature 323 336 1.9E-16 T 22-04-2016 HRM2_RS04320 6434a1c2bfb8bc0d615f7361dc5c3720 470 Gene3D G3DSA:1.10.1060.10 6 148 1.7E-50 T 22-04-2016 HRM2_RS04320 6434a1c2bfb8bc0d615f7361dc5c3720 470 PANTHER PTHR11938:SF108 11 468 1.2E-147 T 22-04-2016 HRM2_RS04320 6434a1c2bfb8bc0d615f7361dc5c3720 470 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 24 134 9.6E-44 T 22-04-2016 IPR028261 Dihydroprymidine dehydrogenase domain II HRM2_RS04320 6434a1c2bfb8bc0d615f7361dc5c3720 470 Gene3D G3DSA:3.50.50.60 149 246 2.2E-18 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS04320 6434a1c2bfb8bc0d615f7361dc5c3720 470 Gene3D G3DSA:3.50.50.60 247 391 3.0E-49 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS04320 6434a1c2bfb8bc0d615f7361dc5c3720 470 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 21 466 1.6E-180 T 22-04-2016 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101|MetaCyc: PWY-7230 HRM2_RS01680 15eb7a9ed3069aa250ee300723ddb14d 188 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 4 28 4.3E-4 T 22-04-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal HRM2_RS01680 15eb7a9ed3069aa250ee300723ddb14d 188 Gene3D G3DSA:3.40.50.740 177 188 6.2E-12 T 22-04-2016 HRM2_RS01680 15eb7a9ed3069aa250ee300723ddb14d 188 Gene3D G3DSA:3.40.50.740 102 145 6.2E-12 T 22-04-2016 HRM2_RS01680 15eb7a9ed3069aa250ee300723ddb14d 188 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 44 96 1.0E-16 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS01680 15eb7a9ed3069aa250ee300723ddb14d 188 SMART SM00926 43 97 4.7E-19 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS01680 15eb7a9ed3069aa250ee300723ddb14d 188 Gene3D G3DSA:2.20.25.90 39 101 2.8E-22 T 22-04-2016 HRM2_RS01680 15eb7a9ed3069aa250ee300723ddb14d 188 PANTHER PTHR11615:SF126 1 188 1.0E-49 T 22-04-2016 HRM2_RS01680 15eb7a9ed3069aa250ee300723ddb14d 188 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 48 65 - T 22-04-2016 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 HRM2_RS01680 15eb7a9ed3069aa250ee300723ddb14d 188 PANTHER PTHR11615 1 188 1.0E-49 T 22-04-2016 HRM2_RS01680 15eb7a9ed3069aa250ee300723ddb14d 188 SUPERFAMILY SSF53706 38 188 1.27E-49 T 22-04-2016 HRM2_RS04545 56574803d2e21c5f5a7d18085c5b52d5 390 Pfam PF06725 3D domain 305 386 5.9E-18 T 22-04-2016 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 HRM2_RS04545 56574803d2e21c5f5a7d18085c5b52d5 390 Gene3D G3DSA:2.40.40.10 199 389 4.6E-45 T 22-04-2016 IPR009009 RlpA-like protein, double-psi beta-barrel domain HRM2_RS04545 56574803d2e21c5f5a7d18085c5b52d5 390 Gene3D G3DSA:2.40.40.10 80 187 2.3E-15 T 22-04-2016 IPR009009 RlpA-like protein, double-psi beta-barrel domain HRM2_RS04545 56574803d2e21c5f5a7d18085c5b52d5 390 PIRSF PIRSF019422 1 390 9.2E-115 T 22-04-2016 IPR026044 Membrane-bound lytic murein transglycosylase A HRM2_RS04545 56574803d2e21c5f5a7d18085c5b52d5 390 SUPERFAMILY SSF50685 3 389 3.1E-106 T 22-04-2016 IPR009009 RlpA-like protein, double-psi beta-barrel domain HRM2_RS04545 56574803d2e21c5f5a7d18085c5b52d5 390 SMART SM00925 128 287 1.1E-65 T 22-04-2016 IPR005300 Lytic transglycosylase MltA GO:0004553 HRM2_RS04545 56574803d2e21c5f5a7d18085c5b52d5 390 Pfam PF03562 MltA specific insert domain 82 287 1.2E-66 T 22-04-2016 IPR005300 Lytic transglycosylase MltA GO:0004553 HRM2_RS04545 56574803d2e21c5f5a7d18085c5b52d5 390 PANTHER PTHR30124:SF0 93 389 5.5E-92 T 22-04-2016 HRM2_RS04545 56574803d2e21c5f5a7d18085c5b52d5 390 PANTHER PTHR30124 93 389 5.5E-92 T 22-04-2016 HRM2_RS11790 48111b690f40ab704ecaff0a41246af9 122 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 118 1.4E-11 T 22-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain HRM2_RS11790 48111b690f40ab704ecaff0a41246af9 122 PANTHER PTHR10374 1 119 3.2E-25 T 22-04-2016 HRM2_RS11790 48111b690f40ab704ecaff0a41246af9 122 PANTHER PTHR10374:SF8 1 119 3.2E-25 T 22-04-2016 HRM2_RS11790 48111b690f40ab704ecaff0a41246af9 122 Gene3D G3DSA:3.10.180.10 2 120 9.9E-28 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HRM2_RS11790 48111b690f40ab704ecaff0a41246af9 122 SUPERFAMILY SSF54593 4 119 3.85E-24 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HRM2_RS10115 c7293d43881ed71887ab95ff65d85be7 275 Pfam PF10043 Predicted periplasmic lipoprotein (DUF2279) 71 160 1.5E-37 T 22-04-2016 IPR018736 Protein of unknown function DUF2279, periplasmic lipoprotein HRM2_RS21180 a52a79448293a64389aa9e9687d3f411 846 PANTHER PTHR30489 1 192 8.7E-178 T 22-04-2016 HRM2_RS21180 a52a79448293a64389aa9e9687d3f411 846 PANTHER PTHR30489 233 846 8.7E-178 T 22-04-2016 HRM2_RS21180 a52a79448293a64389aa9e9687d3f411 846 PANTHER PTHR30489:SF6 1 192 8.7E-178 T 22-04-2016 HRM2_RS21180 a52a79448293a64389aa9e9687d3f411 846 PANTHER PTHR30489:SF6 233 846 8.7E-178 T 22-04-2016 HRM2_RS21180 a52a79448293a64389aa9e9687d3f411 846 Pfam PF12704 MacB-like periplasmic core domain 21 229 3.1E-6 T 22-04-2016 IPR025857 MacB-like periplasmic core domain HRM2_RS21180 a52a79448293a64389aa9e9687d3f411 846 Pfam PF02687 FtsX-like permease family 722 836 6.4E-16 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 HRM2_RS21180 a52a79448293a64389aa9e9687d3f411 846 Pfam PF02687 FtsX-like permease family 262 381 8.0E-13 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 HRM2_RS17450 7f04c813b50fb8518c70420f3f0a6c6e 590 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 147 171 1.4E-7 T 22-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 HRM2_RS17450 7f04c813b50fb8518c70420f3f0a6c6e 590 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 288 307 1.4E-7 T 22-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 HRM2_RS17450 7f04c813b50fb8518c70420f3f0a6c6e 590 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 209 233 1.4E-7 T 22-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 HRM2_RS17450 7f04c813b50fb8518c70420f3f0a6c6e 590 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 117 136 1.4E-7 T 22-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 HRM2_RS17450 7f04c813b50fb8518c70420f3f0a6c6e 590 Pfam PF00361 Proton-conducting membrane transporter 111 380 9.9E-43 T 22-04-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: REACT_6305 HRM2_RS17450 7f04c813b50fb8518c70420f3f0a6c6e 590 PANTHER PTHR22773 1 491 9.2E-188 T 22-04-2016 HRM2_RS17450 7f04c813b50fb8518c70420f3f0a6c6e 590 PANTHER PTHR22773:SF80 1 491 9.2E-188 T 22-04-2016 HRM2_RS06870 a68404b16473b0d52634e318a8b767be 1124 PANTHER PTHR33490 1 509 4.3E-236 T 22-04-2016 HRM2_RS06870 a68404b16473b0d52634e318a8b767be 1124 SMART SM00460 172 248 4.0E-20 T 22-04-2016 IPR002931 Transglutaminase-like HRM2_RS06870 a68404b16473b0d52634e318a8b767be 1124 PANTHER PTHR33490:SF1 1 509 4.3E-236 T 22-04-2016 HRM2_RS06870 a68404b16473b0d52634e318a8b767be 1124 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 6 84 1.4E-23 T 22-04-2016 IPR013589 Bacterial transglutaminase-like, N-terminal HRM2_RS06870 a68404b16473b0d52634e318a8b767be 1124 Pfam PF01841 Transglutaminase-like superfamily 129 246 1.0E-16 T 22-04-2016 IPR002931 Transglutaminase-like HRM2_RS06870 a68404b16473b0d52634e318a8b767be 1124 Gene3D G3DSA:3.90.260.10 177 249 1.2E-9 T 22-04-2016 IPR002931 Transglutaminase-like HRM2_RS06870 a68404b16473b0d52634e318a8b767be 1124 SUPERFAMILY SSF54001 8 337 7.57E-64 T 22-04-2016 HRM2_RS06870 a68404b16473b0d52634e318a8b767be 1124 Pfam PF09899 Putative amidoligase enzyme (DUF2126) 276 1119 0.0 T 22-04-2016 IPR018667 Domain of unknown function DUF2126 HRM2_RS14980 1ccb61f338c8de91abd89d8408f4ebfa 244 Gene3D G3DSA:3.40.50.620 9 193 2.4E-20 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS14980 1ccb61f338c8de91abd89d8408f4ebfa 244 PIRSF PIRSF004976 3 244 2.1E-54 T 22-04-2016 IPR012089 2-thiocytidine tRNA biosynthesis protein, TtcA GO:0008033 HRM2_RS14980 1ccb61f338c8de91abd89d8408f4ebfa 244 SUPERFAMILY SSF52402 7 220 3.1E-48 T 22-04-2016 HRM2_RS14980 1ccb61f338c8de91abd89d8408f4ebfa 244 PANTHER PTHR11807:SF16 5 244 4.0E-65 T 22-04-2016 HRM2_RS14980 1ccb61f338c8de91abd89d8408f4ebfa 244 PANTHER PTHR11807 5 244 4.0E-65 T 22-04-2016 HRM2_RS14980 1ccb61f338c8de91abd89d8408f4ebfa 244 Pfam PF01171 PP-loop family 29 211 4.2E-16 T 22-04-2016 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal HRM2_RS10585 658820ad12efdcf0e4f06613be3e71aa 355 PANTHER PTHR24960 272 348 9.6E-12 T 22-04-2016 HRM2_RS10585 658820ad12efdcf0e4f06613be3e71aa 355 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 309 320 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS10585 658820ad12efdcf0e4f06613be3e71aa 355 Pfam PF14697 4Fe-4S dicluster domain 272 325 2.9E-11 T 22-04-2016 HRM2_RS10585 658820ad12efdcf0e4f06613be3e71aa 355 Gene3D G3DSA:3.30.70.20 266 331 2.2E-19 T 22-04-2016 HRM2_RS10585 658820ad12efdcf0e4f06613be3e71aa 355 PANTHER PTHR24960:SF17 272 348 9.6E-12 T 22-04-2016 HRM2_RS10585 658820ad12efdcf0e4f06613be3e71aa 355 SUPERFAMILY SSF54862 240 331 3.71E-20 T 22-04-2016 HRM2_RS06755 7318551ca39f70dc75cf57a93b8937e5 337 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 9 300 2.6E-58 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 HRM2_RS06755 7318551ca39f70dc75cf57a93b8937e5 337 PANTHER PTHR30480 5 329 2.6E-75 T 22-04-2016 HRM2_RS06755 7318551ca39f70dc75cf57a93b8937e5 337 Gene3D G3DSA:3.20.20.300 13 330 8.2E-74 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 HRM2_RS06755 7318551ca39f70dc75cf57a93b8937e5 337 SUPERFAMILY SSF51445 13 329 1.58E-64 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily HRM2_RS06755 7318551ca39f70dc75cf57a93b8937e5 337 PANTHER PTHR30480:SF5 5 329 2.6E-75 T 22-04-2016 HRM2_RS19675 7cb1920396ad95b00f1267465ae9f394 412 Gene3D G3DSA:3.40.47.10 18 117 6.0E-24 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS19675 7cb1920396ad95b00f1267465ae9f394 412 Gene3D G3DSA:3.40.47.10 224 249 6.0E-24 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS19675 7cb1920396ad95b00f1267465ae9f394 412 SUPERFAMILY SSF53901 3 255 4.4E-39 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS19675 7cb1920396ad95b00f1267465ae9f394 412 PIRSF PIRSF000429 1 406 9.6E-54 T 22-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 HRM2_RS19675 7cb1920396ad95b00f1267465ae9f394 412 Gene3D G3DSA:3.40.47.10 172 209 2.0E-14 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS19675 7cb1920396ad95b00f1267465ae9f394 412 Gene3D G3DSA:3.40.47.10 265 387 2.0E-14 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS19675 7cb1920396ad95b00f1267465ae9f394 412 Pfam PF02803 Thiolase, C-terminal domain 286 383 3.1E-7 T 22-04-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 HRM2_RS19675 7cb1920396ad95b00f1267465ae9f394 412 PANTHER PTHR18919 1 409 1.1E-89 T 22-04-2016 HRM2_RS19675 7cb1920396ad95b00f1267465ae9f394 412 Pfam PF00108 Thiolase, N-terminal domain 4 213 1.5E-14 T 22-04-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 HRM2_RS19675 7cb1920396ad95b00f1267465ae9f394 412 PANTHER PTHR18919:SF8 1 409 1.1E-89 T 22-04-2016 HRM2_RS19675 7cb1920396ad95b00f1267465ae9f394 412 SUPERFAMILY SSF53901 286 397 1.0E-25 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS16515 b80bc9cbf9106423e1f4ba079a21ef9e 335 PRINTS PR01438 Universal stress protein signature 159 177 2.7E-15 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS16515 b80bc9cbf9106423e1f4ba079a21ef9e 335 PRINTS PR01438 Universal stress protein signature 284 296 2.7E-15 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS16515 b80bc9cbf9106423e1f4ba079a21ef9e 335 PRINTS PR01438 Universal stress protein signature 302 324 2.7E-15 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS16515 b80bc9cbf9106423e1f4ba079a21ef9e 335 SUPERFAMILY SSF52402 5 142 1.42E-28 T 22-04-2016 HRM2_RS16515 b80bc9cbf9106423e1f4ba079a21ef9e 335 Pfam PF00582 Universal stress protein family 6 142 2.2E-24 T 22-04-2016 IPR006016 UspA GO:0006950 HRM2_RS16515 b80bc9cbf9106423e1f4ba079a21ef9e 335 Pfam PF00582 Universal stress protein family 160 324 2.2E-27 T 22-04-2016 IPR006016 UspA GO:0006950 HRM2_RS16515 b80bc9cbf9106423e1f4ba079a21ef9e 335 PANTHER PTHR31964 143 332 3.0E-28 T 22-04-2016 HRM2_RS16515 b80bc9cbf9106423e1f4ba079a21ef9e 335 SUPERFAMILY SSF52402 159 325 1.33E-29 T 22-04-2016 HRM2_RS16515 b80bc9cbf9106423e1f4ba079a21ef9e 335 PANTHER PTHR31964:SF45 143 332 3.0E-28 T 22-04-2016 HRM2_RS16515 b80bc9cbf9106423e1f4ba079a21ef9e 335 Gene3D G3DSA:3.40.50.620 158 325 5.8E-32 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS16515 b80bc9cbf9106423e1f4ba079a21ef9e 335 Gene3D G3DSA:3.40.50.620 5 143 1.1E-30 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS06880 5b0c3c2196a58ac5ebac81cc6dab5c03 291 PANTHER PTHR33490:SF6 1 289 3.7E-73 T 22-04-2016 HRM2_RS06880 5b0c3c2196a58ac5ebac81cc6dab5c03 291 Gene3D G3DSA:3.90.260.10 174 252 6.2E-13 T 22-04-2016 IPR002931 Transglutaminase-like HRM2_RS06880 5b0c3c2196a58ac5ebac81cc6dab5c03 291 SUPERFAMILY SSF54001 88 271 2.24E-42 T 22-04-2016 HRM2_RS06880 5b0c3c2196a58ac5ebac81cc6dab5c03 291 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 3 81 3.2E-21 T 22-04-2016 IPR013589 Bacterial transglutaminase-like, N-terminal HRM2_RS06880 5b0c3c2196a58ac5ebac81cc6dab5c03 291 Pfam PF01841 Transglutaminase-like superfamily 133 244 9.6E-23 T 22-04-2016 IPR002931 Transglutaminase-like HRM2_RS06880 5b0c3c2196a58ac5ebac81cc6dab5c03 291 SMART SM00460 176 246 8.3E-19 T 22-04-2016 IPR002931 Transglutaminase-like HRM2_RS06880 5b0c3c2196a58ac5ebac81cc6dab5c03 291 PANTHER PTHR33490 1 289 3.7E-73 T 22-04-2016 HRM2_RS00655 3db20f4fc2b7830e9432c77c86b4220b 289 SUPERFAMILY SSF52768 20 284 1.73E-62 T 22-04-2016 HRM2_RS00655 3db20f4fc2b7830e9432c77c86b4220b 289 PIRSF PIRSF036979 11 288 7.9E-53 T 22-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 HRM2_RS00655 3db20f4fc2b7830e9432c77c86b4220b 289 PANTHER PTHR11358 26 281 1.5E-77 T 22-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 HRM2_RS00655 3db20f4fc2b7830e9432c77c86b4220b 289 Gene3D G3DSA:3.40.800.10 22 284 6.3E-63 T 22-04-2016 IPR023696 Ureohydrolase domain HRM2_RS00655 3db20f4fc2b7830e9432c77c86b4220b 289 PANTHER PTHR11358:SF34 26 281 1.5E-77 T 22-04-2016 HRM2_RS00655 3db20f4fc2b7830e9432c77c86b4220b 289 TIGRFAM TIGR01230 agmatinase: agmatinase 26 283 1.4E-58 T 22-04-2016 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|UniPathway: UPA00534 HRM2_RS00655 3db20f4fc2b7830e9432c77c86b4220b 289 Pfam PF00491 Arginase family 25 281 5.4E-62 T 22-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 HRM2_RS00235 f521daa012c159eb45dc9da38b28a39a 210 SMART SM01018 1 84 6.9E-26 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain HRM2_RS00235 f521daa012c159eb45dc9da38b28a39a 210 Gene3D G3DSA:3.40.50.280 75 208 4.6E-47 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS00235 f521daa012c159eb45dc9da38b28a39a 210 SUPERFAMILY SSF47644 3 81 3.92E-21 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain HRM2_RS00235 f521daa012c159eb45dc9da38b28a39a 210 Pfam PF02607 B12 binding domain 6 77 3.4E-18 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain HRM2_RS00235 f521daa012c159eb45dc9da38b28a39a 210 Pfam PF02310 B12 binding domain 90 192 1.8E-25 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS00235 f521daa012c159eb45dc9da38b28a39a 210 SUPERFAMILY SSF52242 69 207 2.75E-41 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS00235 f521daa012c159eb45dc9da38b28a39a 210 Gene3D G3DSA:1.10.1240.10 5 74 8.8E-21 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain HRM2_RS22730 2fcf9697acd77d1d926c1ba03ae010fd 809 Gene3D G3DSA:3.30.470.20 291 398 2.7E-22 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS22730 2fcf9697acd77d1d926c1ba03ae010fd 809 Gene3D G3DSA:3.50.30.10 439 528 1.3E-14 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS22730 2fcf9697acd77d1d926c1ba03ae010fd 809 SUPERFAMILY SSF52009 425 523 9.29E-15 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS22730 2fcf9697acd77d1d926c1ba03ae010fd 809 PANTHER PTHR22931 113 523 2.8E-57 T 22-04-2016 HRM2_RS22730 2fcf9697acd77d1d926c1ba03ae010fd 809 PANTHER PTHR22931:SF7 113 523 2.8E-57 T 22-04-2016 HRM2_RS22730 2fcf9697acd77d1d926c1ba03ae010fd 809 Pfam PF00391 PEP-utilising enzyme, mobile domain 446 514 3.6E-11 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS22730 2fcf9697acd77d1d926c1ba03ae010fd 809 Gene3D G3DSA:3.30.1490.20 113 290 4.9E-45 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HRM2_RS22730 2fcf9697acd77d1d926c1ba03ae010fd 809 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 126 404 8.2E-57 T 22-04-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 HRM2_RS22730 2fcf9697acd77d1d926c1ba03ae010fd 809 SUPERFAMILY SSF56059 113 403 1.53E-61 T 22-04-2016 HRM2_RS06210 10ff8e2fed4f8ee4f1b90c435eea219c 156 SMART SM00769 32 153 5.7E-10 T 22-04-2016 IPR013990 Water stress and hypersensitive response domain GO:0009269 HRM2_RS06210 10ff8e2fed4f8ee4f1b90c435eea219c 156 Pfam PF03168 Late embryogenesis abundant protein 53 137 2.5E-12 T 22-04-2016 IPR004864 Late embryogenesis abundant protein, LEA-14 HRM2_RS06210 10ff8e2fed4f8ee4f1b90c435eea219c 156 SUPERFAMILY SSF117070 9 137 1.7E-19 T 22-04-2016 HRM2_RS06210 10ff8e2fed4f8ee4f1b90c435eea219c 156 Gene3D G3DSA:2.60.40.10 50 135 2.2E-7 T 22-04-2016 IPR013783 Immunoglobulin-like fold HRM2_RS17465 42fe539dc754fc2c5f6510d865fe71eb 500 PANTHER PTHR22773:SF49 1 491 2.5E-102 T 22-04-2016 HRM2_RS17465 42fe539dc754fc2c5f6510d865fe71eb 500 PANTHER PTHR22773 1 491 2.5E-102 T 22-04-2016 HRM2_RS17465 42fe539dc754fc2c5f6510d865fe71eb 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 382 408 8.1E-7 T 22-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 HRM2_RS17465 42fe539dc754fc2c5f6510d865fe71eb 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 238 262 8.1E-7 T 22-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 HRM2_RS17465 42fe539dc754fc2c5f6510d865fe71eb 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 330 349 8.1E-7 T 22-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 HRM2_RS17465 42fe539dc754fc2c5f6510d865fe71eb 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 166 190 8.1E-7 T 22-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 HRM2_RS17465 42fe539dc754fc2c5f6510d865fe71eb 500 Pfam PF00361 Proton-conducting membrane transporter 133 423 2.6E-51 T 22-04-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: REACT_6305 HRM2_RS22365 6f402a21624713be8942a757baf284fc 228 Pfam PF01564 Spermine/spermidine synthase 53 186 3.5E-6 T 22-04-2016 HRM2_RS22365 6f402a21624713be8942a757baf284fc 228 SUPERFAMILY SSF53335 53 212 1.15E-24 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS22365 6f402a21624713be8942a757baf284fc 228 PANTHER PTHR11558:SF4 7 212 9.5E-26 T 22-04-2016 HRM2_RS22365 6f402a21624713be8942a757baf284fc 228 Gene3D G3DSA:3.40.50.150 56 206 3.9E-25 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS22365 6f402a21624713be8942a757baf284fc 228 PANTHER PTHR11558 7 212 9.5E-26 T 22-04-2016 HRM2_RS15605 f59957dd7a5d84a0f9c8192d6cb0334b 555 PANTHER PTHR11469 1 553 0.0 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 HRM2_RS15605 f59957dd7a5d84a0f9c8192d6cb0334b 555 SUPERFAMILY SSF53697 6 550 2.53E-216 T 22-04-2016 HRM2_RS15605 f59957dd7a5d84a0f9c8192d6cb0334b 555 PRINTS PR00662 Glucose-6-phosphate isomerase signature 466 484 3.2E-54 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 HRM2_RS15605 f59957dd7a5d84a0f9c8192d6cb0334b 555 PRINTS PR00662 Glucose-6-phosphate isomerase signature 498 511 3.2E-54 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 HRM2_RS15605 f59957dd7a5d84a0f9c8192d6cb0334b 555 PRINTS PR00662 Glucose-6-phosphate isomerase signature 150 169 3.2E-54 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 HRM2_RS15605 f59957dd7a5d84a0f9c8192d6cb0334b 555 PRINTS PR00662 Glucose-6-phosphate isomerase signature 484 498 3.2E-54 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 HRM2_RS15605 f59957dd7a5d84a0f9c8192d6cb0334b 555 PRINTS PR00662 Glucose-6-phosphate isomerase signature 339 360 3.2E-54 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 HRM2_RS15605 f59957dd7a5d84a0f9c8192d6cb0334b 555 PRINTS PR00662 Glucose-6-phosphate isomerase signature 262 280 3.2E-54 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 HRM2_RS15605 f59957dd7a5d84a0f9c8192d6cb0334b 555 Gene3D G3DSA:3.40.50.10490 264 502 2.3E-163 T 22-04-2016 HRM2_RS15605 f59957dd7a5d84a0f9c8192d6cb0334b 555 Gene3D G3DSA:3.40.50.10490 5 102 2.3E-163 T 22-04-2016 HRM2_RS15605 f59957dd7a5d84a0f9c8192d6cb0334b 555 Gene3D G3DSA:3.40.50.10490 147 185 2.3E-163 T 22-04-2016 HRM2_RS15605 f59957dd7a5d84a0f9c8192d6cb0334b 555 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 498 515 - T 22-04-2016 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 HRM2_RS15605 f59957dd7a5d84a0f9c8192d6cb0334b 555 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 46 525 40.588 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 HRM2_RS15605 f59957dd7a5d84a0f9c8192d6cb0334b 555 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 266 279 - T 22-04-2016 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 HRM2_RS15605 f59957dd7a5d84a0f9c8192d6cb0334b 555 PANTHER PTHR11469:SF4 1 553 0.0 T 22-04-2016 HRM2_RS15605 f59957dd7a5d84a0f9c8192d6cb0334b 555 Gene3D G3DSA:1.10.1390.10 503 549 1.5E-20 T 22-04-2016 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 HRM2_RS15605 f59957dd7a5d84a0f9c8192d6cb0334b 555 Pfam PF00342 Phosphoglucose isomerase 52 542 1.3E-225 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 HRM2_RS22900 744b5c581d0e49f880f94ad962fd03bf 123 Pfam PF01807 CHC2 zinc finger 10 93 3.9E-6 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS22900 744b5c581d0e49f880f94ad962fd03bf 123 Gene3D G3DSA:3.90.580.10 5 95 3.9E-13 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS22900 744b5c581d0e49f880f94ad962fd03bf 123 SUPERFAMILY SSF57783 13 98 4.08E-11 T 22-04-2016 HRM2_RS19705 744b5c581d0e49f880f94ad962fd03bf 123 Pfam PF01807 CHC2 zinc finger 10 93 3.9E-6 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS19705 744b5c581d0e49f880f94ad962fd03bf 123 Gene3D G3DSA:3.90.580.10 5 95 3.9E-13 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS19705 744b5c581d0e49f880f94ad962fd03bf 123 SUPERFAMILY SSF57783 13 98 4.08E-11 T 22-04-2016 HRM2_RS12980 744b5c581d0e49f880f94ad962fd03bf 123 Pfam PF01807 CHC2 zinc finger 10 93 3.9E-6 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS12980 744b5c581d0e49f880f94ad962fd03bf 123 Gene3D G3DSA:3.90.580.10 5 95 3.9E-13 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS12980 744b5c581d0e49f880f94ad962fd03bf 123 SUPERFAMILY SSF57783 13 98 4.08E-11 T 22-04-2016 HRM2_RS22775 bf9a806347ac445f2f5fb16b07379a37 240 PANTHER PTHR24220:SF414 4 220 6.0E-84 T 22-04-2016 HRM2_RS22775 bf9a806347ac445f2f5fb16b07379a37 240 ProSitePatterns PS00211 ABC transporters family signature. 126 140 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS22775 bf9a806347ac445f2f5fb16b07379a37 240 Gene3D G3DSA:3.40.50.300 2 216 5.5E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22775 bf9a806347ac445f2f5fb16b07379a37 240 SMART SM00382 27 202 1.2E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS22775 bf9a806347ac445f2f5fb16b07379a37 240 PANTHER PTHR24220 4 220 6.0E-84 T 22-04-2016 HRM2_RS22775 bf9a806347ac445f2f5fb16b07379a37 240 SUPERFAMILY SSF52540 2 215 4.42E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22775 bf9a806347ac445f2f5fb16b07379a37 240 Pfam PF00005 ABC transporter 19 153 8.6E-24 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS20000 e66ad88183e2de81e957850471c1dc68 1268 SUPERFAMILY SSF53850 837 1060 1.39E-31 T 22-04-2016 HRM2_RS20000 e66ad88183e2de81e957850471c1dc68 1268 SUPERFAMILY SSF53850 593 815 1.8E-45 T 22-04-2016 HRM2_RS20000 e66ad88183e2de81e957850471c1dc68 1268 Gene3D G3DSA:3.30.70.270 1112 1265 1.3E-47 T 22-04-2016 HRM2_RS20000 e66ad88183e2de81e957850471c1dc68 1268 PANTHER PTHR31528 1 317 3.6E-40 T 22-04-2016 IPR027939 NMT1/THI5 family GO:0009228 UniPathway: UPA00060 HRM2_RS20000 e66ad88183e2de81e957850471c1dc68 1268 Gene3D G3DSA:3.40.190.10 776 815 3.9E-28 T 22-04-2016 HRM2_RS20000 e66ad88183e2de81e957850471c1dc68 1268 Gene3D G3DSA:3.40.190.10 1021 1058 1.7E-12 T 22-04-2016 HRM2_RS20000 e66ad88183e2de81e957850471c1dc68 1268 Gene3D G3DSA:3.40.190.10 529 566 5.7E-20 T 22-04-2016 HRM2_RS20000 e66ad88183e2de81e957850471c1dc68 1268 Gene3D G3DSA:3.40.190.10 346 424 5.7E-20 T 22-04-2016 HRM2_RS20000 e66ad88183e2de81e957850471c1dc68 1268 Gene3D G3DSA:3.40.190.10 841 922 1.7E-12 T 22-04-2016 HRM2_RS20000 e66ad88183e2de81e957850471c1dc68 1268 Gene3D G3DSA:3.40.190.10 590 668 3.9E-28 T 22-04-2016 HRM2_RS20000 e66ad88183e2de81e957850471c1dc68 1268 SUPERFAMILY SSF53850 40 317 4.42E-21 T 22-04-2016 HRM2_RS20000 e66ad88183e2de81e957850471c1dc68 1268 Gene3D G3DSA:3.40.190.10 669 760 9.9E-13 T 22-04-2016 HRM2_RS20000 e66ad88183e2de81e957850471c1dc68 1268 Gene3D G3DSA:3.40.190.10 923 1016 3.0E-11 T 22-04-2016 HRM2_RS20000 e66ad88183e2de81e957850471c1dc68 1268 Gene3D G3DSA:3.40.190.10 425 519 8.3E-5 T 22-04-2016 HRM2_RS20000 e66ad88183e2de81e957850471c1dc68 1268 Pfam PF09084 NMT1/THI5 like 47 250 9.7E-34 T 22-04-2016 IPR015168 SsuA/THI5-like HRM2_RS20000 e66ad88183e2de81e957850471c1dc68 1268 Gene3D G3DSA:3.40.190.10 122 188 5.1E-4 T 22-04-2016 HRM2_RS20000 e66ad88183e2de81e957850471c1dc68 1268 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 1106 1265 3.3E-47 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS20000 e66ad88183e2de81e957850471c1dc68 1268 SMART SM00267 1099 1267 1.3E-57 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS20000 e66ad88183e2de81e957850471c1dc68 1268 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 593 815 1.1E-35 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS20000 e66ad88183e2de81e957850471c1dc68 1268 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 349 566 7.9E-29 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS20000 e66ad88183e2de81e957850471c1dc68 1268 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 844 1058 1.6E-21 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS20000 e66ad88183e2de81e957850471c1dc68 1268 SMART SM00062 592 816 1.4E-25 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS20000 e66ad88183e2de81e957850471c1dc68 1268 SMART SM00062 348 569 7.7E-7 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS20000 e66ad88183e2de81e957850471c1dc68 1268 SMART SM00062 842 1061 6.3E-20 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS20000 e66ad88183e2de81e957850471c1dc68 1268 SUPERFAMILY SSF55073 1115 1265 1.73E-46 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS20000 e66ad88183e2de81e957850471c1dc68 1268 Pfam PF00990 Diguanylate cyclase, GGDEF domain 1111 1263 1.7E-41 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS20000 e66ad88183e2de81e957850471c1dc68 1268 SUPERFAMILY SSF53850 349 566 1.12E-33 T 22-04-2016 HRM2_RS02795 1b0ac242e33398c9b1e3734c355311e2 451 SMART SM00448 4 115 2.5E-36 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS02795 1b0ac242e33398c9b1e3734c355311e2 451 Gene3D G3DSA:3.40.50.300 140 316 3.2E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02795 1b0ac242e33398c9b1e3734c355311e2 451 SUPERFAMILY SSF52540 143 388 7.46E-70 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02795 1b0ac242e33398c9b1e3734c355311e2 451 Gene3D G3DSA:1.10.8.60 317 391 9.2E-26 T 22-04-2016 HRM2_RS02795 1b0ac242e33398c9b1e3734c355311e2 451 Pfam PF02954 Bacterial regulatory protein, Fis family 407 447 1.0E-9 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS02795 1b0ac242e33398c9b1e3734c355311e2 451 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 357 366 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS02795 1b0ac242e33398c9b1e3734c355311e2 451 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 168 181 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS02795 1b0ac242e33398c9b1e3734c355311e2 451 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 230 245 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS02795 1b0ac242e33398c9b1e3734c355311e2 451 PANTHER PTHR32071 1 451 1.6E-194 T 22-04-2016 HRM2_RS02795 1b0ac242e33398c9b1e3734c355311e2 451 Gene3D G3DSA:3.40.50.2300 3 124 8.9E-39 T 22-04-2016 HRM2_RS02795 1b0ac242e33398c9b1e3734c355311e2 451 SUPERFAMILY SSF52172 1 188 1.35E-47 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS02795 1b0ac242e33398c9b1e3734c355311e2 451 PANTHER PTHR32071:SF18 1 451 1.6E-194 T 22-04-2016 HRM2_RS02795 1b0ac242e33398c9b1e3734c355311e2 451 Pfam PF00158 Sigma-54 interaction domain 144 310 3.2E-65 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS02795 1b0ac242e33398c9b1e3734c355311e2 451 Pfam PF00072 Response regulator receiver domain 6 115 1.1E-29 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS02795 1b0ac242e33398c9b1e3734c355311e2 451 SUPERFAMILY SSF46689 357 450 4.03E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS02795 1b0ac242e33398c9b1e3734c355311e2 451 SMART SM00382 164 307 5.2E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS02795 1b0ac242e33398c9b1e3734c355311e2 451 Gene3D G3DSA:1.10.10.60 405 446 3.0E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS15700 ff8e763502caed99b83b2e8b90c9d989 683 PANTHER PTHR18866 26 562 1.7E-176 T 22-04-2016 HRM2_RS15700 ff8e763502caed99b83b2e8b90c9d989 683 PANTHER PTHR18866 592 683 1.7E-176 T 22-04-2016 HRM2_RS15700 ff8e763502caed99b83b2e8b90c9d989 683 PANTHER PTHR18866:SF109 26 562 1.7E-176 T 22-04-2016 HRM2_RS15700 ff8e763502caed99b83b2e8b90c9d989 683 PANTHER PTHR18866:SF109 592 683 1.7E-176 T 22-04-2016 HRM2_RS15700 ff8e763502caed99b83b2e8b90c9d989 683 Gene3D G3DSA:2.40.50.100 615 683 2.1E-23 T 22-04-2016 HRM2_RS15700 ff8e763502caed99b83b2e8b90c9d989 683 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 639 656 - T 22-04-2016 IPR001882 Biotin-binding site HRM2_RS15700 ff8e763502caed99b83b2e8b90c9d989 683 SUPERFAMILY SSF51230 609 683 3.93E-21 T 22-04-2016 IPR011053 Single hybrid motif HRM2_RS15700 ff8e763502caed99b83b2e8b90c9d989 683 Pfam PF00364 Biotin-requiring enzyme 617 682 1.5E-17 T 22-04-2016 IPR000089 Biotin/lipoyl attachment HRM2_RS15700 ff8e763502caed99b83b2e8b90c9d989 683 Pfam PF02436 Conserved carboxylase domain 321 498 9.7E-52 T 22-04-2016 IPR003379 Carboxylase, conserved domain HRM2_RS15700 ff8e763502caed99b83b2e8b90c9d989 683 SUPERFAMILY SSF89000 327 479 4.32E-45 T 22-04-2016 HRM2_RS15700 ff8e763502caed99b83b2e8b90c9d989 683 SUPERFAMILY SSF51569 22 301 6.59E-82 T 22-04-2016 HRM2_RS15700 ff8e763502caed99b83b2e8b90c9d989 683 Gene3D G3DSA:3.20.20.70 21 299 5.4E-106 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS15700 ff8e763502caed99b83b2e8b90c9d989 683 Pfam PF00682 HMGL-like 25 295 1.9E-41 T 22-04-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 HRM2_RS04820 56678f6f60e120e4aef708cf92c57fb3 298 SUPERFAMILY SSF53850 92 286 8.32E-18 T 22-04-2016 HRM2_RS04820 56678f6f60e120e4aef708cf92c57fb3 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 5.9E-15 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HRM2_RS04820 56678f6f60e120e4aef708cf92c57fb3 298 SUPERFAMILY SSF46785 1 110 8.95E-17 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS04820 56678f6f60e120e4aef708cf92c57fb3 298 Pfam PF03466 LysR substrate binding domain 94 269 1.1E-11 T 22-04-2016 IPR005119 LysR, substrate-binding HRM2_RS04820 56678f6f60e120e4aef708cf92c57fb3 298 PANTHER PTHR30579:SF2 1 294 5.7E-113 T 22-04-2016 HRM2_RS04820 56678f6f60e120e4aef708cf92c57fb3 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.7E-7 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HRM2_RS04820 56678f6f60e120e4aef708cf92c57fb3 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.7E-7 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HRM2_RS04820 56678f6f60e120e4aef708cf92c57fb3 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.7E-7 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HRM2_RS04820 56678f6f60e120e4aef708cf92c57fb3 298 PANTHER PTHR30579 1 294 5.7E-113 T 22-04-2016 HRM2_RS04820 56678f6f60e120e4aef708cf92c57fb3 298 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 2 291 6.1E-111 T 22-04-2016 IPR017685 HTH-type transcriptional regulator ArgP HRM2_RS04820 56678f6f60e120e4aef708cf92c57fb3 298 Gene3D G3DSA:3.40.190.10 92 197 7.9E-44 T 22-04-2016 HRM2_RS04820 56678f6f60e120e4aef708cf92c57fb3 298 Gene3D G3DSA:1.10.10.10 1 80 4.2E-17 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS12195 91617bf3f8b717d086e27aff5ff62ac9 207 PANTHER PTHR26402:SF151 1 207 3.5E-38 T 22-04-2016 HRM2_RS12195 91617bf3f8b717d086e27aff5ff62ac9 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 189 9.1E-7 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS12195 91617bf3f8b717d086e27aff5ff62ac9 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 177 9.1E-7 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS12195 91617bf3f8b717d086e27aff5ff62ac9 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 147 161 9.1E-7 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS12195 91617bf3f8b717d086e27aff5ff62ac9 207 Pfam PF00072 Response regulator receiver domain 3 114 9.6E-13 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS12195 91617bf3f8b717d086e27aff5ff62ac9 207 Gene3D G3DSA:1.10.10.10 152 207 1.4E-16 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS12195 91617bf3f8b717d086e27aff5ff62ac9 207 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 199 7.3E-13 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS12195 91617bf3f8b717d086e27aff5ff62ac9 207 SMART SM00421 144 201 3.0E-13 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS12195 91617bf3f8b717d086e27aff5ff62ac9 207 Gene3D G3DSA:3.40.50.2300 1 151 5.4E-22 T 22-04-2016 HRM2_RS12195 91617bf3f8b717d086e27aff5ff62ac9 207 SMART SM00448 1 114 3.5E-6 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS12195 91617bf3f8b717d086e27aff5ff62ac9 207 SUPERFAMILY SSF46894 137 207 1.19E-15 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HRM2_RS12195 91617bf3f8b717d086e27aff5ff62ac9 207 SUPERFAMILY SSF52172 1 132 3.7E-18 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS12195 91617bf3f8b717d086e27aff5ff62ac9 207 PANTHER PTHR26402 1 207 3.5E-38 T 22-04-2016 HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 PRINTS PR00344 Bacterial sensor protein C-terminal signature 492 502 2.7E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 PRINTS PR00344 Bacterial sensor protein C-terminal signature 530 543 2.7E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 PRINTS PR00344 Bacterial sensor protein C-terminal signature 505 523 2.7E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 PRINTS PR00344 Bacterial sensor protein C-terminal signature 474 488 2.7E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 SUPERFAMILY SSF55785 146 255 3.14E-15 T 22-04-2016 IPR000014 PAS domain HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 432 543 3.3E-18 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 Gene3D G3DSA:3.30.450.20 23 147 5.8E-15 T 22-04-2016 HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 Pfam PF13426 PAS domain 62 149 0.0017 T 22-04-2016 IPR000014 PAS domain HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 SMART SM00091 162 230 0.022 T 22-04-2016 IPR000014 PAS domain HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 SMART SM00091 36 107 20.0 T 22-04-2016 IPR000014 PAS domain HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 163 277 2.2E-11 T 22-04-2016 IPR000014 PAS domain HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 32 157 1.3E-13 T 22-04-2016 IPR000014 PAS domain HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 Gene3D G3DSA:1.10.287.130 288 313 1.3E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 Gene3D G3DSA:1.10.287.130 346 375 1.3E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 PANTHER PTHR24423:SF450 342 543 1.5E-81 T 22-04-2016 HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 PANTHER PTHR24423:SF450 90 130 1.5E-81 T 22-04-2016 HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 PANTHER PTHR24423:SF450 146 315 1.5E-81 T 22-04-2016 HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 SMART SM00388 287 379 4.2E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 Gene3D G3DSA:3.30.450.20 148 258 4.7E-15 T 22-04-2016 HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 Pfam PF00512 His Kinase A (phospho-acceptor) domain 287 376 1.6E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 SUPERFAMILY SSF55874 368 544 8.64E-33 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 SMART SM00387 427 544 2.7E-18 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 SUPERFAMILY SSF47384 283 376 1.79E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 SUPERFAMILY SSF55785 23 148 5.23E-16 T 22-04-2016 IPR000014 PAS domain HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 PANTHER PTHR24423 342 543 1.5E-81 T 22-04-2016 HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 PANTHER PTHR24423 90 130 1.5E-81 T 22-04-2016 HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 PANTHER PTHR24423 146 315 1.5E-81 T 22-04-2016 HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 Gene3D G3DSA:3.30.565.10 404 543 2.6E-34 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS08580 c242666dcae523a3f966c10b27a5112d 544 Pfam PF00989 PAS fold 164 243 9.0E-9 T 22-04-2016 IPR013767 PAS fold GO:0006355 HRM2_RS05510 dcfc4d85e4efa9682878605b9d894079 450 Gene3D G3DSA:1.10.8.60 313 387 4.1E-25 T 22-04-2016 HRM2_RS05510 dcfc4d85e4efa9682878605b9d894079 450 Pfam PF00158 Sigma-54 interaction domain 141 306 1.1E-65 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS05510 dcfc4d85e4efa9682878605b9d894079 450 SUPERFAMILY SSF52172 5 185 2.13E-48 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS05510 dcfc4d85e4efa9682878605b9d894079 450 SUPERFAMILY SSF52540 140 382 4.05E-70 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05510 dcfc4d85e4efa9682878605b9d894079 450 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 226 241 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS05510 dcfc4d85e4efa9682878605b9d894079 450 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 353 362 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS05510 dcfc4d85e4efa9682878605b9d894079 450 SMART SM00448 3 114 1.0E-38 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS05510 dcfc4d85e4efa9682878605b9d894079 450 PANTHER PTHR32071 1 438 3.5E-173 T 22-04-2016 HRM2_RS05510 dcfc4d85e4efa9682878605b9d894079 450 SMART SM00382 160 303 2.8E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS05510 dcfc4d85e4efa9682878605b9d894079 450 Gene3D G3DSA:3.40.50.2300 4 133 6.1E-40 T 22-04-2016 HRM2_RS05510 dcfc4d85e4efa9682878605b9d894079 450 Pfam PF00072 Response regulator receiver domain 5 114 3.6E-32 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS05510 dcfc4d85e4efa9682878605b9d894079 450 Gene3D G3DSA:3.40.50.300 137 312 6.6E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17620 a976df6cb70a4d0e745272a8481a3c33 688 SUPERFAMILY SSF46548 287 397 1.15E-19 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS17620 a976df6cb70a4d0e745272a8481a3c33 688 Pfam PF02754 Cysteine-rich domain 574 661 3.4E-18 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS17620 a976df6cb70a4d0e745272a8481a3c33 688 Pfam PF02754 Cysteine-rich domain 462 536 0.0014 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS17620 a976df6cb70a4d0e745272a8481a3c33 688 PANTHER PTHR11921:SF22 105 686 2.3E-133 T 22-04-2016 HRM2_RS17620 a976df6cb70a4d0e745272a8481a3c33 688 Pfam PF13187 4Fe-4S dicluster domain 306 380 2.3E-11 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS17620 a976df6cb70a4d0e745272a8481a3c33 688 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 367 378 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS17620 a976df6cb70a4d0e745272a8481a3c33 688 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 306 317 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS17620 a976df6cb70a4d0e745272a8481a3c33 688 PANTHER PTHR11921 105 686 2.3E-133 T 22-04-2016 HRM2_RS17620 a976df6cb70a4d0e745272a8481a3c33 688 Gene3D G3DSA:1.10.1060.10 284 399 6.3E-28 T 22-04-2016 HRM2_RS17620 a976df6cb70a4d0e745272a8481a3c33 688 SUPERFAMILY SSF103501 68 263 8.63E-10 T 22-04-2016 IPR023234 NarG-like domain HRM2_RS18640 2c7efceba747f7b412e5ed27e1f77c9b 296 Pfam PF02653 Branched-chain amino acid transport system / permease component 2 281 5.6E-27 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 HRM2_RS18640 2c7efceba747f7b412e5ed27e1f77c9b 296 PANTHER PTHR32196:SF27 2 293 3.0E-113 T 22-04-2016 HRM2_RS18640 2c7efceba747f7b412e5ed27e1f77c9b 296 PANTHER PTHR32196 2 293 3.0E-113 T 22-04-2016 HRM2_RS17410 52897729ed38aaaa1fae27fcfc979747 285 PANTHER PTHR34138 1 279 2.0E-56 T 22-04-2016 HRM2_RS17410 52897729ed38aaaa1fae27fcfc979747 285 Pfam PF04085 rod shape-determining protein MreC 121 265 4.2E-44 T 22-04-2016 IPR007221 Rod shape-determining protein MreC GO:0008360 HRM2_RS17410 52897729ed38aaaa1fae27fcfc979747 285 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 2 268 4.3E-42 T 22-04-2016 IPR007221 Rod shape-determining protein MreC GO:0008360 HRM2_RS17410 52897729ed38aaaa1fae27fcfc979747 285 PIRSF PIRSF038471 1 280 1.1E-65 T 22-04-2016 IPR007221 Rod shape-determining protein MreC GO:0008360 HRM2_RS17410 52897729ed38aaaa1fae27fcfc979747 285 PANTHER PTHR34138:SF1 1 279 2.0E-56 T 22-04-2016 HRM2_RS16665 92498c1bff3e729d2d6ca9ba83275035 173 SUPERFAMILY SSF54862 2 127 6.7E-27 T 22-04-2016 HRM2_RS16665 92498c1bff3e729d2d6ca9ba83275035 173 Gene3D G3DSA:3.30.70.20 56 87 6.0E-10 T 22-04-2016 HRM2_RS16665 92498c1bff3e729d2d6ca9ba83275035 173 Gene3D G3DSA:3.30.70.20 120 147 7.0E-10 T 22-04-2016 HRM2_RS16665 92498c1bff3e729d2d6ca9ba83275035 173 Gene3D G3DSA:3.30.70.20 2 55 7.0E-10 T 22-04-2016 HRM2_RS16665 92498c1bff3e729d2d6ca9ba83275035 173 Gene3D G3DSA:3.30.70.20 88 119 3.4E-11 T 22-04-2016 HRM2_RS16665 92498c1bff3e729d2d6ca9ba83275035 173 PANTHER PTHR11938:SF82 1 125 2.8E-17 T 22-04-2016 HRM2_RS16665 92498c1bff3e729d2d6ca9ba83275035 173 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 81 92 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS16665 92498c1bff3e729d2d6ca9ba83275035 173 Pfam PF00037 4Fe-4S binding domain 75 97 1.4E-6 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS16665 92498c1bff3e729d2d6ca9ba83275035 173 PANTHER PTHR11938 1 125 2.8E-17 T 22-04-2016 HRM2_RS17945 af431733ede2e9a7ed3b2a288233de27 230 PANTHER PTHR23105 21 226 5.5E-77 T 22-04-2016 HRM2_RS17945 af431733ede2e9a7ed3b2a288233de27 230 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 42.285 T 22-04-2016 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 HRM2_RS17945 af431733ede2e9a7ed3b2a288233de27 230 Pfam PF00687 Ribosomal protein L1p/L10e family 34 220 3.9E-54 T 22-04-2016 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein HRM2_RS17945 af431733ede2e9a7ed3b2a288233de27 230 SUPERFAMILY SSF56808 6 225 3.01E-83 T 22-04-2016 IPR023674 Ribosomal protein L1-like HRM2_RS17945 af431733ede2e9a7ed3b2a288233de27 230 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 22-04-2016 IPR023673 Ribosomal protein L1, conserved site HRM2_RS17945 af431733ede2e9a7ed3b2a288233de27 230 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 225 2.5E-99 T 22-04-2016 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 HRM2_RS17945 af431733ede2e9a7ed3b2a288233de27 230 Gene3D G3DSA:3.30.190.20 17 68 2.5E-46 T 22-04-2016 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 HRM2_RS17945 af431733ede2e9a7ed3b2a288233de27 230 Gene3D G3DSA:3.30.190.20 161 226 2.5E-46 T 22-04-2016 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 HRM2_RS17945 af431733ede2e9a7ed3b2a288233de27 230 PANTHER PTHR23105:SF5 21 226 5.5E-77 T 22-04-2016 HRM2_RS17945 af431733ede2e9a7ed3b2a288233de27 230 PIRSF PIRSF002155 1 227 1.0E-80 T 22-04-2016 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 HRM2_RS17945 af431733ede2e9a7ed3b2a288233de27 230 Gene3D G3DSA:3.40.50.790 69 159 4.1E-40 T 22-04-2016 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich HRM2_RS23690 8e6726c69fc1705373b168ef3bb410f5 403 Gene3D G3DSA:3.30.450.20 36 150 1.7E-14 T 22-04-2016 HRM2_RS23690 8e6726c69fc1705373b168ef3bb410f5 403 Gene3D G3DSA:3.30.565.10 243 399 1.5E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS23690 8e6726c69fc1705373b168ef3bb410f5 403 PRINTS PR00344 Bacterial sensor protein C-terminal signature 329 343 5.21E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS23690 8e6726c69fc1705373b168ef3bb410f5 403 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 399 5.21E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS23690 8e6726c69fc1705373b168ef3bb410f5 403 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 380 5.21E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS23690 8e6726c69fc1705373b168ef3bb410f5 403 PRINTS PR00344 Bacterial sensor protein C-terminal signature 347 357 5.21E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS23690 8e6726c69fc1705373b168ef3bb410f5 403 Pfam PF13426 PAS domain 62 156 1.4E-10 T 22-04-2016 IPR000014 PAS domain HRM2_RS23690 8e6726c69fc1705373b168ef3bb410f5 403 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 279 399 2.5E-18 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS23690 8e6726c69fc1705373b168ef3bb410f5 403 SUPERFAMILY SSF47384 161 237 2.55E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS23690 8e6726c69fc1705373b168ef3bb410f5 403 SMART SM00091 44 112 0.0035 T 22-04-2016 IPR000014 PAS domain HRM2_RS23690 8e6726c69fc1705373b168ef3bb410f5 403 SUPERFAMILY SSF55874 229 400 1.02E-35 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS23690 8e6726c69fc1705373b168ef3bb410f5 403 SMART SM00387 278 402 1.0E-28 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS23690 8e6726c69fc1705373b168ef3bb410f5 403 SUPERFAMILY SSF55785 36 153 1.74E-13 T 22-04-2016 IPR000014 PAS domain HRM2_RS23690 8e6726c69fc1705373b168ef3bb410f5 403 PANTHER PTHR24423:SF458 24 402 7.6E-85 T 22-04-2016 HRM2_RS23690 8e6726c69fc1705373b168ef3bb410f5 403 PANTHER PTHR24423 24 402 7.6E-85 T 22-04-2016 HRM2_RS23690 8e6726c69fc1705373b168ef3bb410f5 403 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 41 164 2.2E-12 T 22-04-2016 IPR000014 PAS domain HRM2_RS19300 24b6428e90a0d92e9554929c0988c250 438 Pfam PF13416 Bacterial extracellular solute-binding protein 99 392 9.7E-26 T 22-04-2016 HRM2_RS19300 24b6428e90a0d92e9554929c0988c250 438 PANTHER PTHR30006 272 438 4.5E-101 T 22-04-2016 HRM2_RS19300 24b6428e90a0d92e9554929c0988c250 438 PANTHER PTHR30006 64 250 4.5E-101 T 22-04-2016 HRM2_RS19300 24b6428e90a0d92e9554929c0988c250 438 Gene3D G3DSA:3.40.190.10 197 356 1.5E-5 T 22-04-2016 HRM2_RS19300 24b6428e90a0d92e9554929c0988c250 438 PIRSF PIRSF029172 6 438 1.2E-129 T 22-04-2016 IPR027020 Protein ynjB HRM2_RS19300 24b6428e90a0d92e9554929c0988c250 438 SUPERFAMILY SSF53850 75 431 5.72E-28 T 22-04-2016 HRM2_RS19300 24b6428e90a0d92e9554929c0988c250 438 Gene3D G3DSA:3.40.190.10 74 192 6.5E-14 T 22-04-2016 HRM2_RS19300 24b6428e90a0d92e9554929c0988c250 438 Gene3D G3DSA:3.40.190.10 357 385 6.5E-14 T 22-04-2016 HRM2_RS19300 24b6428e90a0d92e9554929c0988c250 438 PANTHER PTHR30006:SF12 272 438 4.5E-101 T 22-04-2016 HRM2_RS19300 24b6428e90a0d92e9554929c0988c250 438 PANTHER PTHR30006:SF12 64 250 4.5E-101 T 22-04-2016 HRM2_RS17655 223dd7d53105ad2d7d41479f66d80053 209 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 206 32.054 T 22-04-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UniPathway: UPA00031 HRM2_RS17655 223dd7d53105ad2d7d41479f66d80053 209 PANTHER PTHR21235 2 203 1.3E-69 T 22-04-2016 HRM2_RS17655 223dd7d53105ad2d7d41479f66d80053 209 SUPERFAMILY SSF52317 2 206 1.09E-47 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS17655 223dd7d53105ad2d7d41479f66d80053 209 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 204 1.6E-61 T 22-04-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UniPathway: UPA00031 HRM2_RS17655 223dd7d53105ad2d7d41479f66d80053 209 PANTHER PTHR21235:SF1 2 203 1.3E-69 T 22-04-2016 HRM2_RS17655 223dd7d53105ad2d7d41479f66d80053 209 Pfam PF00117 Glutamine amidotransferase class-I 5 204 4.9E-15 T 22-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 HRM2_RS17655 223dd7d53105ad2d7d41479f66d80053 209 PIRSF PIRSF000495 1 209 6.2E-64 T 22-04-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UniPathway: UPA00031 HRM2_RS17655 223dd7d53105ad2d7d41479f66d80053 209 Gene3D G3DSA:3.40.50.880 1 206 3.6E-71 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS25120 73cd20b494da1036eeaf59bf901659fd 328 Gene3D G3DSA:3.40.50.2000 1 144 5.3E-31 T 22-04-2016 HRM2_RS25120 73cd20b494da1036eeaf59bf901659fd 328 SUPERFAMILY SSF53756 1 317 6.99E-80 T 22-04-2016 HRM2_RS25120 73cd20b494da1036eeaf59bf901659fd 328 PANTHER PTHR30160 1 328 4.0E-56 T 22-04-2016 HRM2_RS25120 73cd20b494da1036eeaf59bf901659fd 328 PANTHER PTHR30160:SF1 1 328 4.0E-56 T 22-04-2016 HRM2_RS25120 73cd20b494da1036eeaf59bf901659fd 328 Gene3D G3DSA:3.40.50.2000 162 317 8.5E-49 T 22-04-2016 HRM2_RS25120 73cd20b494da1036eeaf59bf901659fd 328 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 66 301 1.3E-39 T 22-04-2016 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 HRM2_RS14620 992d60ddeaa2baf2ff621c14a3b1d4c3 111 SUPERFAMILY SSF161098 13 109 2.88E-13 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS14620 992d60ddeaa2baf2ff621c14a3b1d4c3 111 PANTHER PTHR30177:SF4 1 110 3.4E-32 T 22-04-2016 HRM2_RS14620 992d60ddeaa2baf2ff621c14a3b1d4c3 111 Gene3D G3DSA:1.10.3720.10 9 110 1.5E-10 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS14620 992d60ddeaa2baf2ff621c14a3b1d4c3 111 PANTHER PTHR30177 1 110 3.4E-32 T 22-04-2016 HRM2_RS22800 495635060e2f0b9c4d2dd593d47c0b5a 724 Gene3D G3DSA:3.40.50.261 372 527 1.9E-26 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS22800 495635060e2f0b9c4d2dd593d47c0b5a 724 SUPERFAMILY SSF56059 18 226 3.91E-42 T 22-04-2016 HRM2_RS22800 495635060e2f0b9c4d2dd593d47c0b5a 724 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 392 529 5.6E-45 T 22-04-2016 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain HRM2_RS22800 495635060e2f0b9c4d2dd593d47c0b5a 724 Gene3D G3DSA:3.40.50.261 528 617 9.1E-5 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS22800 495635060e2f0b9c4d2dd593d47c0b5a 724 Pfam PF13549 ATP-grasp domain 13 223 3.0E-60 T 22-04-2016 HRM2_RS22800 495635060e2f0b9c4d2dd593d47c0b5a 724 Gene3D G3DSA:3.30.470.20 94 223 1.3E-8 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS22800 495635060e2f0b9c4d2dd593d47c0b5a 724 PANTHER PTHR33303 13 125 1.6E-96 T 22-04-2016 HRM2_RS22800 495635060e2f0b9c4d2dd593d47c0b5a 724 PANTHER PTHR33303 232 617 1.6E-96 T 22-04-2016 HRM2_RS22800 495635060e2f0b9c4d2dd593d47c0b5a 724 SUPERFAMILY SSF52210 681 720 8.11E-21 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS22800 495635060e2f0b9c4d2dd593d47c0b5a 724 SUPERFAMILY SSF52210 535 639 8.11E-21 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS22800 495635060e2f0b9c4d2dd593d47c0b5a 724 SUPERFAMILY SSF52210 372 532 7.2E-35 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS22800 495635060e2f0b9c4d2dd593d47c0b5a 724 Gene3D G3DSA:3.30.470.20 23 61 8.4E-6 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS22800 495635060e2f0b9c4d2dd593d47c0b5a 724 SMART SM00881 246 341 3.1E-16 T 22-04-2016 IPR003781 CoA-binding GO:0048037 HRM2_RS22800 495635060e2f0b9c4d2dd593d47c0b5a 724 PANTHER PTHR33303:SF3 13 125 1.6E-96 T 22-04-2016 HRM2_RS22800 495635060e2f0b9c4d2dd593d47c0b5a 724 PANTHER PTHR33303:SF3 232 617 1.6E-96 T 22-04-2016 HRM2_RS22800 495635060e2f0b9c4d2dd593d47c0b5a 724 SUPERFAMILY SSF51735 236 380 2.84E-29 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS22800 495635060e2f0b9c4d2dd593d47c0b5a 724 Pfam PF13380 CoA binding domain 251 375 2.9E-16 T 22-04-2016 IPR003781 CoA-binding GO:0048037 HRM2_RS22800 495635060e2f0b9c4d2dd593d47c0b5a 724 Gene3D G3DSA:3.40.50.720 237 371 7.5E-31 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS02325 a83fa71d8938d182400b5992aecb8891 260 Pfam PF12706 Beta-lactamase superfamily domain 29 212 6.9E-18 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS02325 a83fa71d8938d182400b5992aecb8891 260 SUPERFAMILY SSF56281 10 230 6.68E-39 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS02325 a83fa71d8938d182400b5992aecb8891 260 SMART SM00849 17 195 8.8E-10 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS02325 a83fa71d8938d182400b5992aecb8891 260 PANTHER PTHR13754:SF15 7 240 5.0E-75 T 22-04-2016 HRM2_RS02325 a83fa71d8938d182400b5992aecb8891 260 Gene3D G3DSA:3.60.15.10 15 233 3.9E-30 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS02325 a83fa71d8938d182400b5992aecb8891 260 PANTHER PTHR13754 7 240 5.0E-75 T 22-04-2016 HRM2_RS17095 afa7902947ca2ef71e4aa62b8cc51099 320 PANTHER PTHR32196 25 314 5.9E-17 T 22-04-2016 HRM2_RS17095 afa7902947ca2ef71e4aa62b8cc51099 320 Pfam PF13407 Periplasmic binding protein domain 31 288 1.0E-27 T 22-04-2016 IPR025997 Periplasmic binding protein HRM2_RS17095 afa7902947ca2ef71e4aa62b8cc51099 320 Gene3D G3DSA:3.40.50.2300 139 313 8.5E-23 T 22-04-2016 HRM2_RS17095 afa7902947ca2ef71e4aa62b8cc51099 320 SUPERFAMILY SSF53822 26 314 1.57E-42 T 22-04-2016 IPR028082 Periplasmic binding protein-like I HRM2_RS17095 afa7902947ca2ef71e4aa62b8cc51099 320 Gene3D G3DSA:3.40.50.2300 28 138 2.0E-22 T 22-04-2016 HRM2_RS17095 afa7902947ca2ef71e4aa62b8cc51099 320 PANTHER PTHR32196:SF9 25 314 5.9E-17 T 22-04-2016 HRM2_RS07090 2ebb0f08ba1b68eed070360716c815eb 211 Gene3D G3DSA:1.10.357.10 2 187 1.4E-24 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HRM2_RS07090 2ebb0f08ba1b68eed070360716c815eb 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 60 8.8E-6 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS07090 2ebb0f08ba1b68eed070360716c815eb 211 PANTHER PTHR30055 2 192 2.3E-12 T 22-04-2016 HRM2_RS07090 2ebb0f08ba1b68eed070360716c815eb 211 SUPERFAMILY SSF48498 81 172 9.53E-6 T 22-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal HRM2_RS07090 2ebb0f08ba1b68eed070360716c815eb 211 SUPERFAMILY SSF46689 2 86 2.89E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS13845 1f39e20faa7aae611b22f205bb908ed3 395 PANTHER PTHR11228:SF7 41 263 1.5E-76 T 22-04-2016 HRM2_RS13845 1f39e20faa7aae611b22f205bb908ed3 395 PANTHER PTHR11228:SF7 285 394 1.5E-76 T 22-04-2016 HRM2_RS13845 1f39e20faa7aae611b22f205bb908ed3 395 SUPERFAMILY SSF102114 45 364 9.81E-64 T 22-04-2016 HRM2_RS13845 1f39e20faa7aae611b22f205bb908ed3 395 Pfam PF13186 Iron-sulfur cluster-binding domain 301 356 3.0E-7 T 22-04-2016 IPR023885 4Fe4S-binding SPASM domain HRM2_RS13845 1f39e20faa7aae611b22f205bb908ed3 395 Gene3D G3DSA:3.20.20.70 42 374 3.2E-68 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS13845 1f39e20faa7aae611b22f205bb908ed3 395 PIRSF PIRSF037420 23 395 1.9E-128 T 22-04-2016 IPR017200 Coenzyme PQQ synthesis protein E UniPathway: UPA00539 HRM2_RS13845 1f39e20faa7aae611b22f205bb908ed3 395 Pfam PF13353 4Fe-4S single cluster domain 51 151 1.1E-4 T 22-04-2016 HRM2_RS13845 1f39e20faa7aae611b22f205bb908ed3 395 PANTHER PTHR11228 41 263 1.5E-76 T 22-04-2016 HRM2_RS13845 1f39e20faa7aae611b22f205bb908ed3 395 PANTHER PTHR11228 285 394 1.5E-76 T 22-04-2016 HRM2_RS13845 1f39e20faa7aae611b22f205bb908ed3 395 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 301 384 5.9E-10 T 22-04-2016 IPR023885 4Fe4S-binding SPASM domain HRM2_RS13845 1f39e20faa7aae611b22f205bb908ed3 395 TIGRFAM TIGR04546 rSAM_ahbC_deAc: 12,18-didecarboxysiroheme deacetylase 2 391 3.3E-199 T 22-04-2016 IPR030894 12,18-didecarboxysiroheme deacetylase HRM2_RS13845 1f39e20faa7aae611b22f205bb908ed3 395 Pfam PF04055 Radical SAM superfamily 46 183 3.9E-17 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS00020 4ad008f497a7f95292256397e33438bd 228 SUPERFAMILY SSF74653 142 224 3.53E-26 T 22-04-2016 HRM2_RS00020 4ad008f497a7f95292256397e33438bd 228 PANTHER PTHR33446 53 228 1.1E-21 T 22-04-2016 HRM2_RS00020 4ad008f497a7f95292256397e33438bd 228 Gene3D G3DSA:3.30.1150.10 142 227 1.6E-14 T 22-04-2016 HRM2_RS00020 4ad008f497a7f95292256397e33438bd 228 PANTHER PTHR33446:SF1 53 228 1.1E-21 T 22-04-2016 HRM2_RS00020 4ad008f497a7f95292256397e33438bd 228 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 149 226 3.4E-23 T 22-04-2016 IPR006260 TonB, C-terminal GO:0006810 HRM2_RS00020 4ad008f497a7f95292256397e33438bd 228 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 150 226 3.0E-21 T 22-04-2016 IPR006260 TonB, C-terminal GO:0006810 HRM2_RS00020 4ad008f497a7f95292256397e33438bd 228 PRINTS PR01374 Gram-negative bacterial tonB protein signature 165 183 8.3E-13 T 22-04-2016 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 HRM2_RS00020 4ad008f497a7f95292256397e33438bd 228 PRINTS PR01374 Gram-negative bacterial tonB protein signature 144 165 8.3E-13 T 22-04-2016 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 HRM2_RS00020 4ad008f497a7f95292256397e33438bd 228 PRINTS PR01374 Gram-negative bacterial tonB protein signature 65 75 8.3E-13 T 22-04-2016 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 HRM2_RS00020 4ad008f497a7f95292256397e33438bd 228 PRINTS PR01374 Gram-negative bacterial tonB protein signature 184 201 8.3E-13 T 22-04-2016 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 HRM2_RS04645 3b9a3255e33ae56a440d5ee6f6e26ff8 87 Gene3D G3DSA:3.30.2020.10 3 79 4.9E-18 T 22-04-2016 IPR018841 Protein of unknown function DUF2442 HRM2_RS04645 3b9a3255e33ae56a440d5ee6f6e26ff8 87 Pfam PF10387 Protein of unknown function (DUF2442) 7 79 6.5E-20 T 22-04-2016 IPR018841 Protein of unknown function DUF2442 HRM2_RS04645 3b9a3255e33ae56a440d5ee6f6e26ff8 87 SUPERFAMILY SSF143880 4 80 5.36E-21 T 22-04-2016 IPR018841 Protein of unknown function DUF2442 HRM2_RS16205 2f2a431720156990526b48193b29ab6c 402 PANTHER PTHR24031 1 362 1.4E-184 T 22-04-2016 HRM2_RS16205 2f2a431720156990526b48193b29ab6c 402 PANTHER PTHR24031:SF0 1 362 1.4E-184 T 22-04-2016 HRM2_RS16205 2f2a431720156990526b48193b29ab6c 402 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 151 159 - T 22-04-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site HRM2_RS16205 2f2a431720156990526b48193b29ab6c 402 SMART SM00487 20 220 1.3E-64 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS16205 2f2a431720156990526b48193b29ab6c 402 SMART SM00490 256 337 2.8E-31 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS16205 2f2a431720156990526b48193b29ab6c 402 Pfam PF00271 Helicase conserved C-terminal domain 230 337 4.5E-27 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS16205 2f2a431720156990526b48193b29ab6c 402 Gene3D G3DSA:3.40.50.300 210 368 1.1E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16205 2f2a431720156990526b48193b29ab6c 402 Gene3D G3DSA:3.40.50.300 1 209 3.0E-79 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16205 2f2a431720156990526b48193b29ab6c 402 SUPERFAMILY SSF52540 73 356 1.19E-72 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16205 2f2a431720156990526b48193b29ab6c 402 Pfam PF00270 DEAD/DEAH box helicase 25 193 4.2E-51 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HRM2_RS05745 af6ea8d62a4b406dbfc6274777d8c4e0 336 SUPERFAMILY SSF55326 7 153 9.94E-32 T 22-04-2016 HRM2_RS05745 af6ea8d62a4b406dbfc6274777d8c4e0 336 Pfam PF02769 AIR synthase related protein, C-terminal domain 162 311 1.0E-27 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain HRM2_RS05745 af6ea8d62a4b406dbfc6274777d8c4e0 336 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 6 336 5.4E-140 T 22-04-2016 IPR011854 Hydrogenase expression/formation protein HypE HRM2_RS05745 af6ea8d62a4b406dbfc6274777d8c4e0 336 SUPERFAMILY SSF56042 158 332 2.24E-43 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain HRM2_RS05745 af6ea8d62a4b406dbfc6274777d8c4e0 336 Pfam PF00586 AIR synthase related protein, N-terminal domain 38 150 2.6E-17 T 22-04-2016 IPR016188 PurM-like, N-terminal domain HRM2_RS05745 af6ea8d62a4b406dbfc6274777d8c4e0 336 PANTHER PTHR30303 1 336 9.0E-162 T 22-04-2016 HRM2_RS05745 af6ea8d62a4b406dbfc6274777d8c4e0 336 Gene3D G3DSA:3.30.1330.10 20 152 7.1E-23 T 22-04-2016 IPR016188 PurM-like, N-terminal domain HRM2_RS05745 af6ea8d62a4b406dbfc6274777d8c4e0 336 PANTHER PTHR30303:SF0 1 336 9.0E-162 T 22-04-2016 HRM2_RS05745 af6ea8d62a4b406dbfc6274777d8c4e0 336 PIRSF PIRSF005644 1 336 1.2E-127 T 22-04-2016 IPR011854 Hydrogenase expression/formation protein HypE HRM2_RS05745 af6ea8d62a4b406dbfc6274777d8c4e0 336 Gene3D G3DSA:3.90.650.10 161 313 1.0E-25 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 SUPERFAMILY SSF50621 456 576 4.6E-5 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 PANTHER PTHR11482:SF36 441 599 5.6E-214 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 PANTHER PTHR11482:SF36 2 372 5.6E-214 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 425 563 1.2E-24 T 22-04-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 100 349 1.3E-36 T 22-04-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Reactome: REACT_13 HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 339 358 7.9E-16 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 245 258 7.9E-16 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 544 557 7.9E-16 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 104 122 7.9E-16 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 128 140 7.9E-16 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 PRINTS PR01180 Arginine decarboxylase signature 72 87 7.1E-64 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 PRINTS PR01180 Arginine decarboxylase signature 152 167 7.1E-64 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 PRINTS PR01180 Arginine decarboxylase signature 96 110 7.1E-64 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 PRINTS PR01180 Arginine decarboxylase signature 202 224 7.1E-64 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 PRINTS PR01180 Arginine decarboxylase signature 491 516 7.1E-64 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 PRINTS PR01180 Arginine decarboxylase signature 466 487 7.1E-64 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 PRINTS PR01180 Arginine decarboxylase signature 329 346 7.1E-64 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 PRINTS PR01180 Arginine decarboxylase signature 178 199 7.1E-64 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 PRINTS PR01180 Arginine decarboxylase signature 544 565 7.1E-64 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 Gene3D G3DSA:3.20.20.10 74 334 7.3E-51 T 22-04-2016 IPR029066 PLP-binding barrel HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 Gene3D G3DSA:2.40.37.10 335 362 9.5E-12 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 Gene3D G3DSA:2.40.37.10 453 578 9.5E-12 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 SUPERFAMILY SSF51419 74 351 7.85E-58 T 22-04-2016 IPR029066 PLP-binding barrel HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 PIRSF PIRSF001336 1 639 3.8E-250 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 PANTHER PTHR11482 441 599 5.6E-214 T 22-04-2016 HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 PANTHER PTHR11482 2 372 5.6E-214 T 22-04-2016 HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 TIGRFAM TIGR01273 speA: arginine decarboxylase 10 637 3.9E-223 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 HRM2_RS00670 f8b6b2583b55a5166a42a9edfc82f659 639 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 104 122 - T 22-04-2016 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site Reactome: REACT_13 HRM2_RS13055 b377a88021d786ecb776fa905443234e 251 SUPERFAMILY SSF56672 66 251 3.74E-39 T 22-04-2016 HRM2_RS13055 b377a88021d786ecb776fa905443234e 251 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 125 251 5.9E-25 T 22-04-2016 IPR000477 Reverse transcriptase domain HRM2_RS13055 b377a88021d786ecb776fa905443234e 251 PANTHER PTHR19446:SF107 66 251 2.0E-51 T 22-04-2016 HRM2_RS13055 b377a88021d786ecb776fa905443234e 251 PANTHER PTHR19446 66 251 2.0E-51 T 22-04-2016 HRM2_RS14490 35be78fe661563b872dac249468a72df 245 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 115 122 - T 22-04-2016 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560|UniPathway: UPA00056 HRM2_RS14490 35be78fe661563b872dac249468a72df 245 PANTHER PTHR32125:SF4 1 237 1.9E-81 T 22-04-2016 HRM2_RS14490 35be78fe661563b872dac249468a72df 245 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 13 238 1.0E-65 T 22-04-2016 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560|UniPathway: UPA00056 HRM2_RS14490 35be78fe661563b872dac249468a72df 245 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 13 237 1.9E-71 T 22-04-2016 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560|UniPathway: UPA00056 HRM2_RS14490 35be78fe661563b872dac249468a72df 245 PANTHER PTHR32125 1 237 1.9E-81 T 22-04-2016 HRM2_RS14490 35be78fe661563b872dac249468a72df 245 SUPERFAMILY SSF53448 12 237 1.51E-56 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS14490 35be78fe661563b872dac249468a72df 245 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 10 241 28.78 T 22-04-2016 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560|UniPathway: UPA00056 HRM2_RS14490 35be78fe661563b872dac249468a72df 245 Gene3D G3DSA:3.90.550.10 11 238 3.3E-72 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS02390 149c66bfdbee752cd4d86811742d3417 235 TIGRFAM TIGR02495 NrdG2: anaerobic ribonucleoside-triphosphate reductase activating protein 3 192 9.9E-62 T 22-04-2016 IPR012840 Anaerobic ribonucleoside-triphosphate reductase activating protein HRM2_RS02390 149c66bfdbee752cd4d86811742d3417 235 PANTHER PTHR11228:SF27 10 188 1.4E-39 T 22-04-2016 HRM2_RS02390 149c66bfdbee752cd4d86811742d3417 235 Pfam PF13353 4Fe-4S single cluster domain 15 122 1.8E-14 T 22-04-2016 HRM2_RS02390 149c66bfdbee752cd4d86811742d3417 235 Gene3D G3DSA:3.20.20.70 15 229 2.2E-28 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS02390 149c66bfdbee752cd4d86811742d3417 235 Pfam PF04055 Radical SAM superfamily 21 150 1.3E-18 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS02390 149c66bfdbee752cd4d86811742d3417 235 SUPERFAMILY SSF102114 14 205 6.02E-25 T 22-04-2016 HRM2_RS02390 149c66bfdbee752cd4d86811742d3417 235 PANTHER PTHR11228 10 188 1.4E-39 T 22-04-2016 HRM2_RS08500 bc54a056d9a2b52d865e7dc4a08c3f44 295 Pfam PF13847 Methyltransferase domain 124 268 1.1E-8 T 22-04-2016 IPR025714 Methyltransferase domain HRM2_RS08500 bc54a056d9a2b52d865e7dc4a08c3f44 295 Gene3D G3DSA:1.10.8.10 8 93 5.8E-28 T 22-04-2016 HRM2_RS08500 bc54a056d9a2b52d865e7dc4a08c3f44 295 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 9 287 5.6E-66 T 22-04-2016 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 HRM2_RS08500 bc54a056d9a2b52d865e7dc4a08c3f44 295 PANTHER PTHR18895:SF64 8 289 1.5E-92 T 22-04-2016 HRM2_RS08500 bc54a056d9a2b52d865e7dc4a08c3f44 295 Gene3D G3DSA:3.40.50.150 94 289 1.1E-60 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS08500 bc54a056d9a2b52d865e7dc4a08c3f44 295 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 10 291 41.339 T 22-04-2016 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 HRM2_RS08500 bc54a056d9a2b52d865e7dc4a08c3f44 295 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 33 287 5.8E-82 T 22-04-2016 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 HRM2_RS08500 bc54a056d9a2b52d865e7dc4a08c3f44 295 PANTHER PTHR18895 8 289 1.5E-92 T 22-04-2016 HRM2_RS08500 bc54a056d9a2b52d865e7dc4a08c3f44 295 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 194 200 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HRM2_RS08500 bc54a056d9a2b52d865e7dc4a08c3f44 295 SUPERFAMILY SSF53335 10 288 2.02E-54 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS18770 96a9f157ed57e5597132e153b6d657ad 365 PANTHER PTHR13697 7 349 2.6E-103 T 22-04-2016 HRM2_RS18770 96a9f157ed57e5597132e153b6d657ad 365 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 110 126 1.0E-69 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS18770 96a9f157ed57e5597132e153b6d657ad 365 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 137 154 1.0E-69 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS18770 96a9f157ed57e5597132e153b6d657ad 365 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 11 30 1.0E-69 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS18770 96a9f157ed57e5597132e153b6d657ad 365 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 193 210 1.0E-69 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS18770 96a9f157ed57e5597132e153b6d657ad 365 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 229 241 1.0E-69 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS18770 96a9f157ed57e5597132e153b6d657ad 365 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 36 49 1.0E-69 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS18770 96a9f157ed57e5597132e153b6d657ad 365 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 175 191 1.0E-69 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS18770 96a9f157ed57e5597132e153b6d657ad 365 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 278 300 1.0E-69 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS18770 96a9f157ed57e5597132e153b6d657ad 365 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 155 173 1.0E-69 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS18770 96a9f157ed57e5597132e153b6d657ad 365 SUPERFAMILY SSF53784 4 352 1.96E-109 T 22-04-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS18770 96a9f157ed57e5597132e153b6d657ad 365 Gene3D G3DSA:3.40.50.450 3 230 1.7E-64 T 22-04-2016 HRM2_RS18770 96a9f157ed57e5597132e153b6d657ad 365 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 7 364 38.793 T 22-04-2016 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 HRM2_RS18770 96a9f157ed57e5597132e153b6d657ad 365 Pfam PF00365 Phosphofructokinase 8 314 9.4E-96 T 22-04-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS18770 96a9f157ed57e5597132e153b6d657ad 365 PIRSF PIRSF000532 5 365 6.5E-114 T 22-04-2016 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 HRM2_RS18770 96a9f157ed57e5597132e153b6d657ad 365 ProSitePatterns PS00433 Phosphofructokinase signature. 282 300 - T 22-04-2016 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS07780 9a3894def28206610f0f3f07ebf2e36e 339 Gene3D G3DSA:3.40.50.1100 110 326 2.4E-62 T 22-04-2016 HRM2_RS07780 9a3894def28206610f0f3f07ebf2e36e 339 PANTHER PTHR10314 2 339 2.8E-109 T 22-04-2016 HRM2_RS07780 9a3894def28206610f0f3f07ebf2e36e 339 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 11 318 1.5E-52 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HRM2_RS07780 9a3894def28206610f0f3f07ebf2e36e 339 PIRSF PIRSF006278 1 334 6.1E-94 T 22-04-2016 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase HRM2_RS07780 9a3894def28206610f0f3f07ebf2e36e 339 SUPERFAMILY SSF53686 4 329 2.06E-86 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HRM2_RS07780 9a3894def28206610f0f3f07ebf2e36e 339 TIGRFAM TIGR01275 ACC_deam_rel: pyridoxal phosphate-dependent enzymes, D-cysteine desulfhydrase family 14 327 7.4E-93 T 22-04-2016 IPR005966 D-cysteine desulfhydrase GO:0003824 KEGG: 00270+4.4.1.15 HRM2_RS07780 9a3894def28206610f0f3f07ebf2e36e 339 PANTHER PTHR10314:SF105 2 339 2.8E-109 T 22-04-2016 HRM2_RS19560 88a606ea957fa2822debd38b5155f7a4 1040 Gene3D G3DSA:3.40.50.300 309 469 7.7E-20 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19560 88a606ea957fa2822debd38b5155f7a4 1040 Pfam PF00271 Helicase conserved C-terminal domain 542 644 4.7E-10 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS19560 88a606ea957fa2822debd38b5155f7a4 1040 Pfam PF11907 Domain of unknown function (DUF3427) 842 1030 2.8E-25 T 22-04-2016 IPR021835 Protein of unknown function DUF3427 HRM2_RS19560 88a606ea957fa2822debd38b5155f7a4 1040 SUPERFAMILY SSF56024 155 271 8.16E-6 T 22-04-2016 HRM2_RS19560 88a606ea957fa2822debd38b5155f7a4 1040 PANTHER PTHR24031:SF311 260 267 4.5E-25 T 22-04-2016 HRM2_RS19560 88a606ea957fa2822debd38b5155f7a4 1040 PANTHER PTHR24031:SF311 483 645 4.5E-25 T 22-04-2016 HRM2_RS19560 88a606ea957fa2822debd38b5155f7a4 1040 PANTHER PTHR24031:SF311 332 463 4.5E-25 T 22-04-2016 HRM2_RS19560 88a606ea957fa2822debd38b5155f7a4 1040 Pfam PF13091 PLD-like domain 156 267 2.5E-9 T 22-04-2016 IPR025202 Phospholipase D-like domain HRM2_RS19560 88a606ea957fa2822debd38b5155f7a4 1040 Pfam PF04851 Type III restriction enzyme, res subunit 312 465 5.3E-29 T 22-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HRM2_RS19560 88a606ea957fa2822debd38b5155f7a4 1040 PANTHER PTHR24031 260 267 4.5E-25 T 22-04-2016 HRM2_RS19560 88a606ea957fa2822debd38b5155f7a4 1040 PANTHER PTHR24031 483 645 4.5E-25 T 22-04-2016 HRM2_RS19560 88a606ea957fa2822debd38b5155f7a4 1040 PANTHER PTHR24031 332 463 4.5E-25 T 22-04-2016 HRM2_RS19560 88a606ea957fa2822debd38b5155f7a4 1040 SUPERFAMILY SSF52540 362 505 9.25E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19560 88a606ea957fa2822debd38b5155f7a4 1040 SUPERFAMILY SSF52540 538 659 9.25E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19560 88a606ea957fa2822debd38b5155f7a4 1040 Gene3D G3DSA:3.40.50.300 549 661 2.9E-18 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19560 88a606ea957fa2822debd38b5155f7a4 1040 SMART SM00487 308 492 6.9E-9 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS19560 88a606ea957fa2822debd38b5155f7a4 1040 SMART SM00490 565 646 8.1E-10 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS19560 88a606ea957fa2822debd38b5155f7a4 1040 Gene3D G3DSA:3.30.870.10 161 272 8.1E-6 T 22-04-2016 HRM2_RS01120 6d8c4d96ef414caa19b22eff292c967d 235 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 5 233 1.5E-67 T 22-04-2016 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 HRM2_RS01120 6d8c4d96ef414caa19b22eff292c967d 235 Gene3D G3DSA:3.40.1010.10 4 132 1.0E-35 T 22-04-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 HRM2_RS01120 6d8c4d96ef414caa19b22eff292c967d 235 SUPERFAMILY SSF53790 4 235 1.2E-43 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 HRM2_RS01120 6d8c4d96ef414caa19b22eff292c967d 235 PANTHER PTHR10882:SF1 6 164 2.4E-37 T 22-04-2016 HRM2_RS01120 6d8c4d96ef414caa19b22eff292c967d 235 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 6 215 3.5E-49 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 HRM2_RS01120 6d8c4d96ef414caa19b22eff292c967d 235 PIRSF PIRSF036427 3 235 2.3E-68 T 22-04-2016 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 HRM2_RS01120 6d8c4d96ef414caa19b22eff292c967d 235 PANTHER PTHR10882 6 164 2.4E-37 T 22-04-2016 HRM2_RS03635 5544ab6181e7d0197240b06d59bf2c4a 620 PANTHER PTHR21432 9 437 4.9E-158 T 22-04-2016 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 HRM2_RS03635 5544ab6181e7d0197240b06d59bf2c4a 620 PANTHER PTHR21432:SF18 9 437 4.9E-158 T 22-04-2016 HRM2_RS03635 5544ab6181e7d0197240b06d59bf2c4a 620 SUPERFAMILY SSF55729 462 599 1.55E-11 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS03635 5544ab6181e7d0197240b06d59bf2c4a 620 Gene3D G3DSA:3.40.1080.10 9 183 6.8E-57 T 22-04-2016 HRM2_RS03635 5544ab6181e7d0197240b06d59bf2c4a 620 Pfam PF00583 Acetyltransferase (GNAT) family 530 598 3.4E-5 T 22-04-2016 IPR000182 GNAT domain GO:0008080 HRM2_RS03635 5544ab6181e7d0197240b06d59bf2c4a 620 SUPERFAMILY SSF100950 190 434 1.09E-59 T 22-04-2016 HRM2_RS03635 5544ab6181e7d0197240b06d59bf2c4a 620 Gene3D G3DSA:3.40.810.20 192 429 9.2E-38 T 22-04-2016 HRM2_RS03635 5544ab6181e7d0197240b06d59bf2c4a 620 Gene3D G3DSA:3.40.630.30 464 599 3.9E-11 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS03635 5544ab6181e7d0197240b06d59bf2c4a 620 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 274 427 2.3E-60 T 22-04-2016 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain HRM2_RS03635 5544ab6181e7d0197240b06d59bf2c4a 620 SUPERFAMILY SSF100950 8 224 3.07E-36 T 22-04-2016 HRM2_RS03635 5544ab6181e7d0197240b06d59bf2c4a 620 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 17 186 7.9E-26 T 22-04-2016 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 HRM2_RS08840 be47b81684c245c98dd0c20acff1ecc7 499 SUPERFAMILY SSF52096 24 182 7.81E-16 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS08840 be47b81684c245c98dd0c20acff1ecc7 499 SUPERFAMILY SSF141322 438 494 3.4E-5 T 22-04-2016 HRM2_RS08840 be47b81684c245c98dd0c20acff1ecc7 499 PANTHER PTHR33507 44 498 5.1E-76 T 22-04-2016 HRM2_RS08840 be47b81684c245c98dd0c20acff1ecc7 499 Pfam PF01957 NfeD-like C-terminal, partner-binding 331 495 2.4E-13 T 22-04-2016 IPR002810 NfeD-like, C-terminal domain HRM2_RS08840 be47b81684c245c98dd0c20acff1ecc7 499 Gene3D G3DSA:3.90.226.10 41 142 4.5E-10 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS08840 be47b81684c245c98dd0c20acff1ecc7 499 Gene3D G3DSA:3.90.226.10 177 206 4.5E-10 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS08840 be47b81684c245c98dd0c20acff1ecc7 499 Gene3D G3DSA:2.40.50.140 441 495 5.3E-5 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS08840 be47b81684c245c98dd0c20acff1ecc7 499 PANTHER PTHR33507:SF1 44 498 5.1E-76 T 22-04-2016 HRM2_RS00050 fe5cdbab684d7edd630a8ea00317da13 404 PANTHER PTHR11751:SF302 18 401 8.3E-185 T 22-04-2016 HRM2_RS00050 fe5cdbab684d7edd630a8ea00317da13 404 Pfam PF00155 Aminotransferase class I and II 37 389 1.5E-55 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HRM2_RS00050 fe5cdbab684d7edd630a8ea00317da13 404 Gene3D G3DSA:3.90.1150.10 264 396 2.3E-39 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS00050 fe5cdbab684d7edd630a8ea00317da13 404 SUPERFAMILY SSF53383 8 397 7.84E-101 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS00050 fe5cdbab684d7edd630a8ea00317da13 404 Gene3D G3DSA:3.40.640.10 50 263 3.5E-53 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS00050 fe5cdbab684d7edd630a8ea00317da13 404 PANTHER PTHR11751 18 401 8.3E-185 T 22-04-2016 HRM2_RS00050 fe5cdbab684d7edd630a8ea00317da13 404 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 242 255 - T 22-04-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Reactome: REACT_13 HRM2_RS05255 1fd8ed2a29a142e501f41d4723de5d3b 114 Gene3D G3DSA:3.30.780.10 41 112 1.7E-25 T 22-04-2016 IPR001950 Translation initiation factor SUI1 GO:0003743|GO:0006413 HRM2_RS05255 1fd8ed2a29a142e501f41d4723de5d3b 114 PANTHER PTHR12789 42 112 3.1E-17 T 22-04-2016 HRM2_RS05255 1fd8ed2a29a142e501f41d4723de5d3b 114 PIRSF PIRSF037511 3 113 3.2E-30 T 22-04-2016 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 HRM2_RS05255 1fd8ed2a29a142e501f41d4723de5d3b 114 Pfam PF01253 Translation initiation factor SUI1 43 108 1.2E-14 T 22-04-2016 IPR001950 Translation initiation factor SUI1 GO:0003743|GO:0006413 HRM2_RS05255 1fd8ed2a29a142e501f41d4723de5d3b 114 SUPERFAMILY SSF55159 6 112 4.45E-25 T 22-04-2016 IPR001950 Translation initiation factor SUI1 GO:0003743|GO:0006413 HRM2_RS04920 86d947a3135ffffb2da6238f1a16a4cf 529 Pfam PF01039 Carboxyl transferase domain 36 519 2.5E-105 T 22-04-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 HRM2_RS04920 86d947a3135ffffb2da6238f1a16a4cf 529 Gene3D G3DSA:3.90.226.10 17 255 2.2E-56 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS04920 86d947a3135ffffb2da6238f1a16a4cf 529 Gene3D G3DSA:3.90.226.10 265 524 3.2E-54 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS04920 86d947a3135ffffb2da6238f1a16a4cf 529 SUPERFAMILY SSF52096 227 511 1.1E-55 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS04920 86d947a3135ffffb2da6238f1a16a4cf 529 PANTHER PTHR22855:SF13 3 529 8.6E-201 T 22-04-2016 HRM2_RS04920 86d947a3135ffffb2da6238f1a16a4cf 529 SUPERFAMILY SSF52096 14 256 5.33E-51 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS04920 86d947a3135ffffb2da6238f1a16a4cf 529 PANTHER PTHR22855 3 529 8.6E-201 T 22-04-2016 HRM2_RS22435 adb61d4eb9366262ada031301c1a019c 324 Gene3D G3DSA:3.40.50.300 3 252 2.0E-70 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22435 adb61d4eb9366262ada031301c1a019c 324 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 228 313 4.5E-25 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HRM2_RS22435 adb61d4eb9366262ada031301c1a019c 324 PANTHER PTHR24220:SF576 6 317 2.2E-168 T 22-04-2016 HRM2_RS22435 adb61d4eb9366262ada031301c1a019c 324 PANTHER PTHR24220 6 317 2.2E-168 T 22-04-2016 HRM2_RS22435 adb61d4eb9366262ada031301c1a019c 324 SUPERFAMILY SSF52540 30 303 9.58E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22435 adb61d4eb9366262ada031301c1a019c 324 SMART SM00382 29 228 1.4E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS22435 adb61d4eb9366262ada031301c1a019c 324 Pfam PF00005 ABC transporter 21 178 2.9E-26 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS22435 adb61d4eb9366262ada031301c1a019c 324 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS22435 adb61d4eb9366262ada031301c1a019c 324 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 294 5.9E-20 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HRM2_RS08505 57feaa527a6a00b2a8b024973b91962e 280 Gene3D G3DSA:1.10.287.610 100 151 1.2E-19 T 22-04-2016 HRM2_RS08505 57feaa527a6a00b2a8b024973b91962e 280 SUPERFAMILY SSF52313 6 232 1.83E-91 T 22-04-2016 IPR023591 Ribosomal protein S2, flavodoxin-like domain HRM2_RS08505 57feaa527a6a00b2a8b024973b91962e 280 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 22-04-2016 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 HRM2_RS08505 57feaa527a6a00b2a8b024973b91962e 280 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 22-04-2016 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 HRM2_RS08505 57feaa527a6a00b2a8b024973b91962e 280 PRINTS PR00395 Ribosomal protein S2 signature 87 104 2.0E-38 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS08505 57feaa527a6a00b2a8b024973b91962e 280 PRINTS PR00395 Ribosomal protein S2 signature 37 46 2.0E-38 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS08505 57feaa527a6a00b2a8b024973b91962e 280 PRINTS PR00395 Ribosomal protein S2 signature 175 186 2.0E-38 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS08505 57feaa527a6a00b2a8b024973b91962e 280 PRINTS PR00395 Ribosomal protein S2 signature 158 175 2.0E-38 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS08505 57feaa527a6a00b2a8b024973b91962e 280 PRINTS PR00395 Ribosomal protein S2 signature 196 210 2.0E-38 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS08505 57feaa527a6a00b2a8b024973b91962e 280 PRINTS PR00395 Ribosomal protein S2 signature 6 24 2.0E-38 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS08505 57feaa527a6a00b2a8b024973b91962e 280 PANTHER PTHR12534 1 268 2.4E-112 T 22-04-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 HRM2_RS08505 57feaa527a6a00b2a8b024973b91962e 280 Gene3D G3DSA:3.40.50.10490 23 99 3.9E-65 T 22-04-2016 HRM2_RS08505 57feaa527a6a00b2a8b024973b91962e 280 Gene3D G3DSA:3.40.50.10490 158 239 3.9E-65 T 22-04-2016 HRM2_RS08505 57feaa527a6a00b2a8b024973b91962e 280 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 4 226 1.1E-102 T 22-04-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 HRM2_RS08505 57feaa527a6a00b2a8b024973b91962e 280 Pfam PF00318 Ribosomal protein S2 9 224 3.1E-95 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS08505 57feaa527a6a00b2a8b024973b91962e 280 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 225 41.01 T 22-04-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 HRM2_RS17375 474a98f8e74b2c7c8869900c313622dc 504 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 501 49.898 T 22-04-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS17375 474a98f8e74b2c7c8869900c313622dc 504 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 371 495 9.0E-45 T 22-04-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS17375 474a98f8e74b2c7c8869900c313622dc 504 PANTHER PTHR15184 1 485 1.6E-292 T 22-04-2016 HRM2_RS17375 474a98f8e74b2c7c8869900c313622dc 504 Gene3D G3DSA:3.40.50.300 95 371 9.7E-114 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17375 474a98f8e74b2c7c8869900c313622dc 504 SUPERFAMILY SSF50615 10 94 1.15E-29 T 22-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS17375 474a98f8e74b2c7c8869900c313622dc 504 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 355 364 - T 22-04-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS17375 474a98f8e74b2c7c8869900c313622dc 504 PIRSF PIRSF039088 1 503 6.0E-251 T 22-04-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS17375 474a98f8e74b2c7c8869900c313622dc 504 SUPERFAMILY SSF47917 373 500 1.52E-42 T 22-04-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS17375 474a98f8e74b2c7c8869900c313622dc 504 Gene3D G3DSA:2.40.30.20 1 93 2.6E-38 T 22-04-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS17375 474a98f8e74b2c7c8869900c313622dc 504 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 500 2.9E-245 T 22-04-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS17375 474a98f8e74b2c7c8869900c313622dc 504 PANTHER PTHR15184:SF3 1 485 1.6E-292 T 22-04-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS17375 474a98f8e74b2c7c8869900c313622dc 504 Gene3D G3DSA:1.20.150.20 373 500 4.5E-48 T 22-04-2016 HRM2_RS17375 474a98f8e74b2c7c8869900c313622dc 504 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 364 6.2E-76 T 22-04-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS17375 474a98f8e74b2c7c8869900c313622dc 504 SUPERFAMILY SSF52540 96 370 6.88E-96 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17375 474a98f8e74b2c7c8869900c313622dc 504 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 26 91 1.9E-16 T 22-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS20810 21762241e9930d08633b3eb3cb84335b 168 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 15 30 6.2E-10 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 HRM2_RS20810 21762241e9930d08633b3eb3cb84335b 168 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 41 53 6.2E-10 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 HRM2_RS20810 21762241e9930d08633b3eb3cb84335b 168 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 97 109 6.2E-10 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 HRM2_RS20810 21762241e9930d08633b3eb3cb84335b 168 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 2 162 1.8E-44 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 HRM2_RS20810 21762241e9930d08633b3eb3cb84335b 168 PIRSF PIRSF001467 1 167 5.4E-26 T 22-04-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 HRM2_RS20810 21762241e9930d08633b3eb3cb84335b 168 PANTHER PTHR11071:SF192 1 164 2.5E-57 T 22-04-2016 HRM2_RS20810 21762241e9930d08633b3eb3cb84335b 168 Gene3D G3DSA:2.40.100.10 2 163 1.6E-50 T 22-04-2016 IPR029000 Cyclophilin-like domain HRM2_RS20810 21762241e9930d08633b3eb3cb84335b 168 SUPERFAMILY SSF50891 2 162 5.41E-55 T 22-04-2016 IPR029000 Cyclophilin-like domain HRM2_RS20810 21762241e9930d08633b3eb3cb84335b 168 PANTHER PTHR11071 1 164 2.5E-57 T 22-04-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 HRM2_RS20810 21762241e9930d08633b3eb3cb84335b 168 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 36 53 - T 22-04-2016 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 HRM2_RS17235 230d528fd18563d6e5b26b1a00f7a17a 412 SUPERFAMILY SSF53474 99 301 6.89E-23 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS17235 230d528fd18563d6e5b26b1a00f7a17a 412 PANTHER PTHR11614:SF89 80 258 3.3E-26 T 22-04-2016 HRM2_RS17235 230d528fd18563d6e5b26b1a00f7a17a 412 PANTHER PTHR11614 80 258 3.3E-26 T 22-04-2016 HRM2_RS17235 230d528fd18563d6e5b26b1a00f7a17a 412 Gene3D G3DSA:3.40.50.1820 93 303 2.5E-31 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS17235 230d528fd18563d6e5b26b1a00f7a17a 412 Pfam PF12146 Serine aminopeptidase, S33 101 223 1.0E-12 T 22-04-2016 IPR022742 Serine aminopeptidase, S33 HRM2_RS22500 974d182bc01d2827307be3d54c93b66a 437 SUPERFAMILY SSF111352 40 413 4.05E-118 T 22-04-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 HRM2_RS22500 974d182bc01d2827307be3d54c93b66a 437 PANTHER PTHR11730:SF6 14 434 6.8E-181 T 22-04-2016 HRM2_RS22500 974d182bc01d2827307be3d54c93b66a 437 Pfam PF00909 Ammonium Transporter Family 45 432 8.6E-125 T 22-04-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 HRM2_RS22500 974d182bc01d2827307be3d54c93b66a 437 ProSitePatterns PS01219 Ammonium transporters signature. 194 219 - T 22-04-2016 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 HRM2_RS22500 974d182bc01d2827307be3d54c93b66a 437 PANTHER PTHR11730 14 434 6.8E-181 T 22-04-2016 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 HRM2_RS22500 974d182bc01d2827307be3d54c93b66a 437 TIGRFAM TIGR00836 amt: ammonium transporter 43 432 3.0E-133 T 22-04-2016 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 HRM2_RS22500 974d182bc01d2827307be3d54c93b66a 437 Gene3D G3DSA:1.10.3430.10 38 413 1.1E-125 T 22-04-2016 IPR029020 Ammonium/urea transporter HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 Pfam PF02321 Outer membrane efflux protein 1309 1481 1.3E-19 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 Pfam PF02321 Outer membrane efflux protein 1085 1278 6.7E-14 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 PANTHER PTHR32063:SF0 1 1037 1.0E-265 T 22-04-2016 HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 SUPERFAMILY SSF82866 812 1030 2.75E-42 T 22-04-2016 HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 Pfam PF00873 AcrB/AcrD/AcrF family 5 1028 3.6E-201 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 Gene3D G3DSA:3.30.2090.10 727 807 1.4E-8 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 Gene3D G3DSA:3.30.2090.10 185 267 4.3E-15 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 SUPERFAMILY SSF82693 42 131 4.19E-22 T 22-04-2016 HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 SUPERFAMILY SSF82693 270 315 1.94E-7 T 22-04-2016 HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 SUPERFAMILY SSF82693 153 184 1.94E-7 T 22-04-2016 HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 Gene3D G3DSA:3.30.70.1320 272 304 7.8E-6 T 22-04-2016 HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 Gene3D G3DSA:3.30.70.1320 140 181 7.8E-6 T 22-04-2016 HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 Gene3D G3DSA:1.10.3850.10 815 1029 3.4E-53 T 22-04-2016 HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 SUPERFAMILY SSF82714 727 807 1.18E-8 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 SUPERFAMILY SSF56954 1079 1492 4.84E-59 T 22-04-2016 HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 PRINTS PR00702 Acriflavin resistance protein family signature 441 464 1.2E-38 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 PRINTS PR00702 Acriflavin resistance protein family signature 466 489 1.2E-38 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.2E-38 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 PRINTS PR00702 Acriflavin resistance protein family signature 331 354 1.2E-38 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 PRINTS PR00702 Acriflavin resistance protein family signature 386 410 1.2E-38 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.2E-38 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 PRINTS PR00702 Acriflavin resistance protein family signature 358 379 1.2E-38 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 Gene3D G3DSA:1.20.1600.10 1161 1336 1.4E-62 T 22-04-2016 HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 Gene3D G3DSA:1.20.1600.10 1380 1491 1.4E-62 T 22-04-2016 HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 Gene3D G3DSA:1.20.1600.10 1083 1111 1.4E-62 T 22-04-2016 HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 Gene3D G3DSA:3.30.70.1430 42 139 2.1E-26 T 22-04-2016 HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 SUPERFAMILY SSF82693 568 667 7.5E-7 T 22-04-2016 HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 SUPERFAMILY SSF82866 302 492 8.24E-33 T 22-04-2016 HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 SUPERFAMILY SSF82714 186 266 2.09E-14 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 PANTHER PTHR32063 1 1037 1.0E-265 T 22-04-2016 HRM2_RS21250 ab2f7a50e37283942f61128f0c8f6682 1494 Gene3D G3DSA:1.20.1640.10 305 497 1.0E-41 T 22-04-2016 HRM2_RS10205 92246468b1a5d17d30b0960eb7434379 645 SMART SM00487 19 214 0.009 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS10205 92246468b1a5d17d30b0960eb7434379 645 Pfam PF00271 Helicase conserved C-terminal domain 313 375 1.1E-4 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS10205 92246468b1a5d17d30b0960eb7434379 645 Gene3D G3DSA:3.40.50.300 22 195 4.0E-11 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10205 92246468b1a5d17d30b0960eb7434379 645 SUPERFAMILY SSF52540 302 379 4.9E-20 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10205 92246468b1a5d17d30b0960eb7434379 645 SUPERFAMILY SSF52540 35 272 4.9E-20 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10205 92246468b1a5d17d30b0960eb7434379 645 Gene3D G3DSA:3.40.50.300 292 388 6.1E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21445 1edb8249c53d5a465cb9979a50101832 214 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 210 36.775 T 22-04-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS21445 1edb8249c53d5a465cb9979a50101832 214 SUPERFAMILY SSF52016 1 208 1.31E-46 T 22-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel HRM2_RS21445 1edb8249c53d5a465cb9979a50101832 214 Pfam PF00694 Aconitase C-terminal domain 1 133 1.9E-25 T 22-04-2016 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS21445 1edb8249c53d5a465cb9979a50101832 214 PANTHER PTHR11670 1 211 3.3E-80 T 22-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS21445 1edb8249c53d5a465cb9979a50101832 214 Gene3D G3DSA:3.20.19.10 1 206 8.1E-34 T 22-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel HRM2_RS21445 1edb8249c53d5a465cb9979a50101832 214 PANTHER PTHR11670:SF27 1 211 3.3E-80 T 22-04-2016 HRM2_RS21445 1edb8249c53d5a465cb9979a50101832 214 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 199 1.8E-63 T 22-04-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HRM2_RS06615 a50d532708c0fb38d3290f478a30fb15 296 PRINTS PR00126 ATP synthase gamma subunit signature 234 253 1.3E-13 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 HRM2_RS06615 a50d532708c0fb38d3290f478a30fb15 296 PRINTS PR00126 ATP synthase gamma subunit signature 265 286 1.3E-13 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 HRM2_RS06615 a50d532708c0fb38d3290f478a30fb15 296 PRINTS PR00126 ATP synthase gamma subunit signature 71 90 1.3E-13 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 HRM2_RS06615 a50d532708c0fb38d3290f478a30fb15 296 PANTHER PTHR11693 1 289 3.0E-22 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 HRM2_RS06615 a50d532708c0fb38d3290f478a30fb15 296 SUPERFAMILY SSF52943 3 285 1.23E-45 T 22-04-2016 IPR023633 ATPase, F1 complex, gamma subunit domain HRM2_RS06615 a50d532708c0fb38d3290f478a30fb15 296 Gene3D G3DSA:1.10.287.80 3 36 8.7E-27 T 22-04-2016 HRM2_RS06615 a50d532708c0fb38d3290f478a30fb15 296 Gene3D G3DSA:1.10.287.80 221 285 8.7E-27 T 22-04-2016 HRM2_RS06615 a50d532708c0fb38d3290f478a30fb15 296 Gene3D G3DSA:3.40.1380.10 64 188 5.4E-8 T 22-04-2016 HRM2_RS06615 a50d532708c0fb38d3290f478a30fb15 296 Pfam PF00231 ATP synthase 3 285 4.1E-46 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 HRM2_RS07095 89395657b60bd63b1eb6ec89a895ec87 373 PANTHER PTHR30002:SF4 4 364 2.0E-38 T 22-04-2016 HRM2_RS07095 89395657b60bd63b1eb6ec89a895ec87 373 Gene3D G3DSA:3.30.70.20 184 254 8.5E-7 T 22-04-2016 HRM2_RS07095 89395657b60bd63b1eb6ec89a895ec87 373 PANTHER PTHR30002 4 364 2.0E-38 T 22-04-2016 HRM2_RS07095 89395657b60bd63b1eb6ec89a895ec87 373 SUPERFAMILY SSF54862 186 255 1.03E-10 T 22-04-2016 HRM2_RS07095 89395657b60bd63b1eb6ec89a895ec87 373 SUPERFAMILY SSF48371 241 372 9.05E-12 T 22-04-2016 IPR016024 Armadillo-type fold GO:0005488 HRM2_RS07095 89395657b60bd63b1eb6ec89a895ec87 373 Pfam PF13484 4Fe-4S double cluster binding domain 184 245 2.9E-12 T 22-04-2016 HRM2_RS07095 89395657b60bd63b1eb6ec89a895ec87 373 Gene3D G3DSA:1.25.10.10 281 372 1.1E-9 T 22-04-2016 IPR011989 Armadillo-like helical HRM2_RS07095 89395657b60bd63b1eb6ec89a895ec87 373 Pfam PF13646 HEAT repeats 292 365 2.2E-6 T 22-04-2016 HRM2_RS16040 d89f6bb23cfde88bd3b7c557f43223e0 411 Gene3D G3DSA:3.40.50.300 221 378 1.0E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16040 d89f6bb23cfde88bd3b7c557f43223e0 411 Pfam PF00271 Helicase conserved C-terminal domain 236 339 8.2E-28 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS16040 d89f6bb23cfde88bd3b7c557f43223e0 411 SMART SM00487 20 223 8.3E-54 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS16040 d89f6bb23cfde88bd3b7c557f43223e0 411 SMART SM00490 259 340 4.8E-29 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS16040 d89f6bb23cfde88bd3b7c557f43223e0 411 PANTHER PTHR24031 1 371 3.6E-152 T 22-04-2016 HRM2_RS16040 d89f6bb23cfde88bd3b7c557f43223e0 411 SUPERFAMILY SSF52540 73 357 1.21E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16040 d89f6bb23cfde88bd3b7c557f43223e0 411 Pfam PF00270 DEAD/DEAH box helicase 25 196 3.7E-50 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HRM2_RS16040 d89f6bb23cfde88bd3b7c557f43223e0 411 Gene3D G3DSA:3.40.50.300 1 220 5.2E-74 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12095 935f37b4f302ab52605b85734fb5f082 105 SUPERFAMILY SSF46785 11 99 1.56E-24 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS12095 935f37b4f302ab52605b85734fb5f082 105 PANTHER PTHR33154:SF10 8 99 1.7E-29 T 22-04-2016 HRM2_RS12095 935f37b4f302ab52605b85734fb5f082 105 PANTHER PTHR33154 8 99 1.7E-29 T 22-04-2016 HRM2_RS12095 935f37b4f302ab52605b85734fb5f082 105 SMART SM00418 18 95 1.8E-21 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HRM2_RS12095 935f37b4f302ab52605b85734fb5f082 105 Pfam PF12840 Helix-turn-helix domain 19 76 1.4E-12 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS12095 935f37b4f302ab52605b85734fb5f082 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 20 35 1.3E-11 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HRM2_RS12095 935f37b4f302ab52605b85734fb5f082 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 1.3E-11 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HRM2_RS12095 935f37b4f302ab52605b85734fb5f082 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 67 82 1.3E-11 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HRM2_RS12095 935f37b4f302ab52605b85734fb5f082 105 Gene3D G3DSA:1.10.10.10 5 100 2.1E-34 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS10970 876546ae3f28f66831d2f94019da40c4 325 Gene3D G3DSA:3.40.50.10490 2 191 1.1E-50 T 22-04-2016 HRM2_RS10970 876546ae3f28f66831d2f94019da40c4 325 Pfam PF00571 CBS domain 196 252 8.5E-7 T 22-04-2016 IPR000644 CBS domain HRM2_RS10970 876546ae3f28f66831d2f94019da40c4 325 Pfam PF00571 CBS domain 264 316 7.8E-13 T 22-04-2016 IPR000644 CBS domain HRM2_RS10970 876546ae3f28f66831d2f94019da40c4 325 Gene3D G3DSA:3.10.580.10 192 315 2.6E-35 T 22-04-2016 HRM2_RS10970 876546ae3f28f66831d2f94019da40c4 325 PIRSF PIRSF004692 1 320 1.8E-122 T 22-04-2016 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 HRM2_RS10970 876546ae3f28f66831d2f94019da40c4 325 PANTHER PTHR38418 28 192 2.1E-38 T 22-04-2016 HRM2_RS10970 876546ae3f28f66831d2f94019da40c4 325 Pfam PF01380 SIS domain 36 166 8.6E-28 T 22-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 HRM2_RS10970 876546ae3f28f66831d2f94019da40c4 325 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 40 310 6.1E-96 T 22-04-2016 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 HRM2_RS10970 876546ae3f28f66831d2f94019da40c4 325 SUPERFAMILY SSF53697 3 315 2.89E-59 T 22-04-2016 HRM2_RS10970 876546ae3f28f66831d2f94019da40c4 325 SMART SM00116 271 319 3.3E-6 T 22-04-2016 IPR000644 CBS domain HRM2_RS10970 876546ae3f28f66831d2f94019da40c4 325 SMART SM00116 205 253 2.4E-6 T 22-04-2016 IPR000644 CBS domain HRM2_RS20530 b5a9b120f1399ce043c2c05568185bbd 937 SUPERFAMILY SSF50692 772 936 1.88E-26 T 22-04-2016 IPR009010 Aspartate decarboxylase-like domain HRM2_RS20530 b5a9b120f1399ce043c2c05568185bbd 937 SUPERFAMILY SSF89155 10 202 2.62E-33 T 22-04-2016 IPR020945 DMSO/Nitrate reductase chaperone HRM2_RS20530 b5a9b120f1399ce043c2c05568185bbd 937 PANTHER PTHR11615 194 937 4.8E-85 T 22-04-2016 HRM2_RS20530 b5a9b120f1399ce043c2c05568185bbd 937 Pfam PF01568 Molydopterin dinucleotide binding domain 811 927 2.7E-13 T 22-04-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 HRM2_RS20530 b5a9b120f1399ce043c2c05568185bbd 937 Pfam PF02613 Nitrate reductase delta subunit 51 171 3.4E-21 T 22-04-2016 IPR020945 DMSO/Nitrate reductase chaperone HRM2_RS20530 b5a9b120f1399ce043c2c05568185bbd 937 PANTHER PTHR11615:SF139 194 937 4.8E-85 T 22-04-2016 HRM2_RS20530 b5a9b120f1399ce043c2c05568185bbd 937 SUPERFAMILY SSF53706 248 811 8.51E-128 T 22-04-2016 HRM2_RS20530 b5a9b120f1399ce043c2c05568185bbd 937 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 246 299 2.4E-11 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS20530 b5a9b120f1399ce043c2c05568185bbd 937 Gene3D G3DSA:2.20.25.90 245 303 1.7E-16 T 22-04-2016 HRM2_RS20530 b5a9b120f1399ce043c2c05568185bbd 937 Gene3D G3DSA:3.40.50.740 558 777 4.6E-43 T 22-04-2016 HRM2_RS20530 b5a9b120f1399ce043c2c05568185bbd 937 Gene3D G3DSA:3.40.50.740 304 369 4.6E-43 T 22-04-2016 HRM2_RS20530 b5a9b120f1399ce043c2c05568185bbd 937 Gene3D G3DSA:3.40.228.10 388 557 2.0E-55 T 22-04-2016 HRM2_RS20530 b5a9b120f1399ce043c2c05568185bbd 937 Gene3D G3DSA:2.40.40.20 791 937 1.2E-27 T 22-04-2016 HRM2_RS20530 b5a9b120f1399ce043c2c05568185bbd 937 Pfam PF00384 Molybdopterin oxidoreductase 302 707 6.2E-51 T 22-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 HRM2_RS20530 b5a9b120f1399ce043c2c05568185bbd 937 Gene3D G3DSA:1.10.3480.10 2 203 2.8E-40 T 22-04-2016 IPR020945 DMSO/Nitrate reductase chaperone HRM2_RS20530 b5a9b120f1399ce043c2c05568185bbd 937 SMART SM00926 245 299 1.2E-12 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS02555 bfaa39b4fc6781a9c294798478c3cec9 449 SUPERFAMILY SSF102114 192 411 6.67E-29 T 22-04-2016 HRM2_RS02555 bfaa39b4fc6781a9c294798478c3cec9 449 SMART SM00729 213 424 1.1E-12 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS02555 bfaa39b4fc6781a9c294798478c3cec9 449 Gene3D G3DSA:3.80.30.20 214 411 2.8E-28 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe HRM2_RS02555 bfaa39b4fc6781a9c294798478c3cec9 449 PANTHER PTHR11918 92 411 2.0E-77 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein HRM2_RS02555 bfaa39b4fc6781a9c294798478c3cec9 449 Pfam PF04055 Radical SAM superfamily 218 378 3.9E-12 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS02555 bfaa39b4fc6781a9c294798478c3cec9 449 SUPERFAMILY SSF52242 112 160 1.91E-5 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS02555 bfaa39b4fc6781a9c294798478c3cec9 449 Pfam PF02310 B12 binding domain 113 180 4.2E-8 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS02555 bfaa39b4fc6781a9c294798478c3cec9 449 PANTHER PTHR11918:SF44 92 411 2.0E-77 T 22-04-2016 HRM2_RS05630 d594487dc6ee801f66727c89e914dc2a 147 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 9 145 6.6E-56 T 22-04-2016 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 HRM2_RS05630 d594487dc6ee801f66727c89e914dc2a 147 PANTHER PTHR30093 5 145 4.0E-59 T 22-04-2016 HRM2_RS05630 d594487dc6ee801f66727c89e914dc2a 147 PANTHER PTHR30093:SF9 5 145 4.0E-59 T 22-04-2016 HRM2_RS05630 d594487dc6ee801f66727c89e914dc2a 147 Gene3D G3DSA:3.30.700.10 11 75 2.2E-10 T 22-04-2016 HRM2_RS05630 d594487dc6ee801f66727c89e914dc2a 147 Pfam PF13633 Prokaryotic N-terminal methylation site 9 32 2.0E-10 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site HRM2_RS05630 d594487dc6ee801f66727c89e914dc2a 147 Pfam PF08334 Type II secretion system (T2SS), protein G 33 144 1.0E-42 T 22-04-2016 IPR013545 Type II secretion system protein G HRM2_RS05630 d594487dc6ee801f66727c89e914dc2a 147 SUPERFAMILY SSF54523 36 145 6.28E-38 T 22-04-2016 HRM2_RS05630 d594487dc6ee801f66727c89e914dc2a 147 PRINTS PR00813 Bacterial general secretion pathway protein G signature 10 35 4.3E-18 T 22-04-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 HRM2_RS05630 d594487dc6ee801f66727c89e914dc2a 147 PRINTS PR00813 Bacterial general secretion pathway protein G signature 46 64 4.3E-18 T 22-04-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 HRM2_RS05630 d594487dc6ee801f66727c89e914dc2a 147 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 30 6.5E-9 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site HRM2_RS05630 d594487dc6ee801f66727c89e914dc2a 147 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 9 29 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site HRM2_RS25445 99e8bd0a969c23318fd1391862963ab9 404 PANTHER PTHR10799:SF750 94 364 1.9E-31 T 22-04-2016 HRM2_RS25445 99e8bd0a969c23318fd1391862963ab9 404 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 201 366 2.9E-52 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS25445 99e8bd0a969c23318fd1391862963ab9 404 SMART SM00267 193 367 3.5E-64 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS25445 99e8bd0a969c23318fd1391862963ab9 404 PANTHER PTHR10799 94 364 1.9E-31 T 22-04-2016 HRM2_RS25445 99e8bd0a969c23318fd1391862963ab9 404 SUPERFAMILY SSF55073 209 366 1.33E-49 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS25445 99e8bd0a969c23318fd1391862963ab9 404 Pfam PF00990 Diguanylate cyclase, GGDEF domain 206 363 1.9E-47 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS25445 99e8bd0a969c23318fd1391862963ab9 404 Gene3D G3DSA:3.30.70.270 206 366 7.4E-54 T 22-04-2016 HRM2_RS04235 aba5194df863751f77b3ef407c057160 339 SMART SM00846 2 151 8.7E-85 T 22-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS04235 aba5194df863751f77b3ef407c057160 339 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 156 317 2.3E-47 T 22-04-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS04235 aba5194df863751f77b3ef407c057160 339 SUPERFAMILY SSF51735 2 165 9.01E-59 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS04235 aba5194df863751f77b3ef407c057160 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 145 163 4.4E-30 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS04235 aba5194df863751f77b3ef407c057160 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 4.4E-30 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS04235 aba5194df863751f77b3ef407c057160 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 4.4E-30 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS04235 aba5194df863751f77b3ef407c057160 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 172 188 4.4E-30 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS04235 aba5194df863751f77b3ef407c057160 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 4.4E-30 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS04235 aba5194df863751f77b3ef407c057160 339 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 149 156 - T 22-04-2016 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS04235 aba5194df863751f77b3ef407c057160 339 Gene3D G3DSA:3.40.50.720 1 158 6.7E-70 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS04235 aba5194df863751f77b3ef407c057160 339 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 151 4.5E-56 T 22-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS04235 aba5194df863751f77b3ef407c057160 339 PIRSF PIRSF000149 1 339 8.4E-109 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS04235 aba5194df863751f77b3ef407c057160 339 PANTHER PTHR10836 1 334 1.0E-176 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS04235 aba5194df863751f77b3ef407c057160 339 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 3 329 7.0E-122 T 22-04-2016 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS04235 aba5194df863751f77b3ef407c057160 339 PANTHER PTHR10836:SF57 1 334 1.0E-176 T 22-04-2016 HRM2_RS04235 aba5194df863751f77b3ef407c057160 339 SUPERFAMILY SSF55347 151 318 1.03E-53 T 22-04-2016 HRM2_RS04235 aba5194df863751f77b3ef407c057160 339 Gene3D G3DSA:3.30.360.10 159 319 1.7E-54 T 22-04-2016 HRM2_RS15275 5484bec6ea24b7bbef5066dfffe0372b 121 Pfam PF02021 Uncharacterised protein family UPF0102 12 102 1.4E-26 T 22-04-2016 IPR003509 Uncharacterised protein family UPF0102 HRM2_RS15275 5484bec6ea24b7bbef5066dfffe0372b 121 Hamap MF_00048 UPF0102 protein YraN [yraN]. 5 115 21.86 T 22-04-2016 IPR003509 Uncharacterised protein family UPF0102 HRM2_RS15275 5484bec6ea24b7bbef5066dfffe0372b 121 PANTHER PTHR34039 1 121 3.5E-36 T 22-04-2016 HRM2_RS15275 5484bec6ea24b7bbef5066dfffe0372b 121 Gene3D G3DSA:3.40.1350.10 12 120 1.2E-33 T 22-04-2016 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 HRM2_RS15275 5484bec6ea24b7bbef5066dfffe0372b 121 SUPERFAMILY SSF52980 11 109 5.15E-22 T 22-04-2016 IPR011335 Restriction endonuclease type II-like HRM2_RS15275 5484bec6ea24b7bbef5066dfffe0372b 121 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 6 120 7.5E-24 T 22-04-2016 IPR003509 Uncharacterised protein family UPF0102 HRM2_RS15275 5484bec6ea24b7bbef5066dfffe0372b 121 PANTHER PTHR34039:SF1 1 121 3.5E-36 T 22-04-2016 HRM2_RS09145 d4b80f7a405c8f198cce3e4306b5188b 363 SUPERFAMILY SSF50331 236 354 1.7E-15 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal HRM2_RS09145 d4b80f7a405c8f198cce3e4306b5188b 363 PANTHER PTHR24220 4 239 5.0E-108 T 22-04-2016 HRM2_RS09145 d4b80f7a405c8f198cce3e4306b5188b 363 PANTHER PTHR24220:SF282 4 239 5.0E-108 T 22-04-2016 HRM2_RS09145 d4b80f7a405c8f198cce3e4306b5188b 363 Gene3D G3DSA:2.40.50.140 287 337 1.4E-6 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS09145 d4b80f7a405c8f198cce3e4306b5188b 363 Gene3D G3DSA:3.40.50.300 3 232 1.7E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09145 d4b80f7a405c8f198cce3e4306b5188b 363 SMART SM00382 27 212 8.6E-5 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS09145 d4b80f7a405c8f198cce3e4306b5188b 363 SUPERFAMILY SSF52540 3 240 3.8E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09145 d4b80f7a405c8f198cce3e4306b5188b 363 Pfam PF00005 ABC transporter 18 160 1.9E-29 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS21480 28cfa5e879d4a7f2909905321067ecfe 396 Gene3D G3DSA:3.40.50.2300 24 152 1.1E-44 T 22-04-2016 HRM2_RS21480 28cfa5e879d4a7f2909905321067ecfe 396 PANTHER PTHR21021:SF19 144 393 5.7E-60 T 22-04-2016 HRM2_RS21480 28cfa5e879d4a7f2909905321067ecfe 396 SMART SM00448 23 136 1.0E-44 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS21480 28cfa5e879d4a7f2909905321067ecfe 396 Pfam PF00072 Response regulator receiver domain 25 137 3.5E-30 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS21480 28cfa5e879d4a7f2909905321067ecfe 396 SUPERFAMILY SSF81606 185 394 5.36E-12 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 HRM2_RS21480 28cfa5e879d4a7f2909905321067ecfe 396 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 205 395 5.5E-43 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 HRM2_RS21480 28cfa5e879d4a7f2909905321067ecfe 396 PANTHER PTHR21021 144 393 5.7E-60 T 22-04-2016 HRM2_RS21480 28cfa5e879d4a7f2909905321067ecfe 396 Gene3D G3DSA:3.60.40.10 308 393 3.1E-4 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 HRM2_RS21480 28cfa5e879d4a7f2909905321067ecfe 396 SMART SM00331 178 395 1.7E-41 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 HRM2_RS21480 28cfa5e879d4a7f2909905321067ecfe 396 SUPERFAMILY SSF52172 24 174 2.85E-45 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS13050 5515d45c70c3a0a05ae9d902aa7f43cc 337 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 17 99 1.5E-12 T 22-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 HRM2_RS13050 5515d45c70c3a0a05ae9d902aa7f43cc 337 PANTHER PTHR30349:SF5 12 313 3.9E-57 T 22-04-2016 HRM2_RS13050 5515d45c70c3a0a05ae9d902aa7f43cc 337 Pfam PF00589 Phage integrase family 126 299 1.2E-30 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS13050 5515d45c70c3a0a05ae9d902aa7f43cc 337 Gene3D G3DSA:1.10.150.130 12 99 1.1E-10 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal HRM2_RS13050 5515d45c70c3a0a05ae9d902aa7f43cc 337 SUPERFAMILY SSF56349 10 308 2.33E-40 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HRM2_RS13050 5515d45c70c3a0a05ae9d902aa7f43cc 337 Gene3D G3DSA:1.10.443.10 126 308 9.7E-40 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS13050 5515d45c70c3a0a05ae9d902aa7f43cc 337 PANTHER PTHR30349 12 313 3.9E-57 T 22-04-2016 HRM2_RS04250 6fe0d7c6a4db8a382966168a47aec2af 578 Gene3D G3DSA:3.90.180.10 39 200 1.4E-18 T 22-04-2016 IPR011032 GroES-like HRM2_RS04250 6fe0d7c6a4db8a382966168a47aec2af 578 SUPERFAMILY SSF51735 330 500 5.67E-16 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS04250 6fe0d7c6a4db8a382966168a47aec2af 578 SUPERFAMILY SSF50129 41 200 1.56E-19 T 22-04-2016 IPR011032 GroES-like HRM2_RS04250 6fe0d7c6a4db8a382966168a47aec2af 578 PANTHER PTHR11695 37 181 2.4E-16 T 22-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 HRM2_RS04250 6fe0d7c6a4db8a382966168a47aec2af 578 PANTHER PTHR11695 332 542 2.4E-16 T 22-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 HRM2_RS04250 6fe0d7c6a4db8a382966168a47aec2af 578 Gene3D G3DSA:3.40.50.720 333 478 7.5E-15 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS04250 6fe0d7c6a4db8a382966168a47aec2af 578 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 49 120 3.6E-8 T 22-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 HRM2_RS04250 6fe0d7c6a4db8a382966168a47aec2af 578 Gene3D G3DSA:3.40.50.720 214 318 8.4E-4 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS19415 bbcf425cba6e9d0b799e9b74e13e9aa3 318 SMART SM00989 157 212 0.0011 T 22-04-2016 IPR004096 4-vinyl reductase, 4VR HRM2_RS19415 bbcf425cba6e9d0b799e9b74e13e9aa3 318 Gene3D G3DSA:3.30.1380.20 101 216 2.8E-17 T 22-04-2016 HRM2_RS19415 bbcf425cba6e9d0b799e9b74e13e9aa3 318 Pfam PF02830 V4R domain 167 210 1.6E-9 T 22-04-2016 IPR004096 4-vinyl reductase, 4VR HRM2_RS19415 bbcf425cba6e9d0b799e9b74e13e9aa3 318 SUPERFAMILY SSF111126 99 211 1.94E-16 T 22-04-2016 IPR024096 NO signalling/Golgi transport ligand-binding domain HRM2_RS16870 7a5a6f7abc10819d64322b6014f729ee 419 Pfam PF00950 ABC 3 transport family 13 277 5.2E-63 T 22-04-2016 IPR001626 ABC-3 GO:0005524|GO:0006810|GO:0016020|GO:0042626 HRM2_RS16870 7a5a6f7abc10819d64322b6014f729ee 419 PANTHER PTHR30477 2 310 3.5E-88 T 22-04-2016 HRM2_RS16870 7a5a6f7abc10819d64322b6014f729ee 419 SUPERFAMILY SSF46785 302 375 6.93E-5 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS16870 7a5a6f7abc10819d64322b6014f729ee 419 SUPERFAMILY SSF81345 7 275 1.44E-35 T 22-04-2016 IPR029022 ABC transporter, BtuC-like HRM2_RS16870 7a5a6f7abc10819d64322b6014f729ee 419 Gene3D G3DSA:1.10.60.10 361 419 1.7E-18 T 22-04-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 HRM2_RS16870 7a5a6f7abc10819d64322b6014f729ee 419 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 351 418 1.5E-21 T 22-04-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 HRM2_RS16870 7a5a6f7abc10819d64322b6014f729ee 419 SMART SM00529 320 410 1.7E-6 T 22-04-2016 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 HRM2_RS16870 7a5a6f7abc10819d64322b6014f729ee 419 PANTHER PTHR30477:SF13 2 310 3.5E-88 T 22-04-2016 HRM2_RS16870 7a5a6f7abc10819d64322b6014f729ee 419 SUPERFAMILY SSF47979 351 418 3.01E-18 T 22-04-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 HRM2_RS16870 7a5a6f7abc10819d64322b6014f729ee 419 Gene3D G3DSA:1.10.3470.10 53 252 3.0E-12 T 22-04-2016 IPR029022 ABC transporter, BtuC-like HRM2_RS07270 78a0ddcfac54a9bdcf21c9a0dbaf86cc 368 Pfam PF01761 3-dehydroquinate synthase 77 321 1.8E-72 T 22-04-2016 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 HRM2_RS07270 78a0ddcfac54a9bdcf21c9a0dbaf86cc 368 PANTHER PTHR21090 77 357 9.0E-67 T 22-04-2016 HRM2_RS07270 78a0ddcfac54a9bdcf21c9a0dbaf86cc 368 SUPERFAMILY SSF56796 7 365 3.14E-73 T 22-04-2016 HRM2_RS07270 78a0ddcfac54a9bdcf21c9a0dbaf86cc 368 Gene3D G3DSA:1.20.1090.10 184 365 2.8E-35 T 22-04-2016 HRM2_RS07270 78a0ddcfac54a9bdcf21c9a0dbaf86cc 368 Gene3D G3DSA:3.40.50.1970 7 183 1.6E-43 T 22-04-2016 HRM2_RS02730 0ff1f84f2309d6817f777294f61988f0 753 SMART SM00487 212 442 1.8E-8 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS02730 0ff1f84f2309d6817f777294f61988f0 753 Pfam PF00271 Helicase conserved C-terminal domain 461 559 1.5E-4 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS02730 0ff1f84f2309d6817f777294f61988f0 753 SUPERFAMILY SSF52540 319 564 3.85E-29 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02730 0ff1f84f2309d6817f777294f61988f0 753 SUPERFAMILY SSF52540 233 288 3.85E-29 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02730 0ff1f84f2309d6817f777294f61988f0 753 Gene3D G3DSA:3.40.50.300 207 410 3.3E-17 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02730 0ff1f84f2309d6817f777294f61988f0 753 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 240 569 1.4E-46 T 22-04-2016 IPR006474 Helicase Cas3, CRISPR-associated, core HRM2_RS02730 0ff1f84f2309d6817f777294f61988f0 753 Pfam PF04851 Type III restriction enzyme, res subunit 220 375 2.5E-11 T 22-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HRM2_RS02730 0ff1f84f2309d6817f777294f61988f0 753 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 34 182 2.3E-15 T 22-04-2016 IPR006483 CRISPR-associated Cas3-HD domain HRM2_RS02730 0ff1f84f2309d6817f777294f61988f0 753 Gene3D G3DSA:3.40.50.300 449 572 4.7E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08835 4ae8df3e3c81bb7279fb4665ffa7e200 215 PANTHER PTHR20855 1 212 3.3E-64 T 22-04-2016 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 HRM2_RS08835 4ae8df3e3c81bb7279fb4665ffa7e200 215 Pfam PF03006 Haemolysin-III related 4 205 9.3E-44 T 22-04-2016 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 HRM2_RS08835 4ae8df3e3c81bb7279fb4665ffa7e200 215 PANTHER PTHR20855:SF43 1 212 3.3E-64 T 22-04-2016 HRM2_RS08835 4ae8df3e3c81bb7279fb4665ffa7e200 215 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 6 211 5.8E-65 T 22-04-2016 IPR005744 Hly-III GO:0016021|GO:0019835 HRM2_RS00645 a79ca2780013171c0ff44e7b044f073a 720 ProSitePatterns PS00436 Peroxidases active site signature. 86 97 - T 22-04-2016 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 HRM2_RS00645 a79ca2780013171c0ff44e7b044f073a 720 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 48 61 3.9E-53 T 22-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 HRM2_RS00645 a79ca2780013171c0ff44e7b044f073a 720 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 22 44 3.9E-53 T 22-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 HRM2_RS00645 a79ca2780013171c0ff44e7b044f073a 720 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 63 88 3.9E-53 T 22-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 HRM2_RS00645 a79ca2780013171c0ff44e7b044f073a 720 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 263 286 3.9E-53 T 22-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 HRM2_RS00645 a79ca2780013171c0ff44e7b044f073a 720 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 474 500 3.9E-53 T 22-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 HRM2_RS00645 a79ca2780013171c0ff44e7b044f073a 720 PRINTS PR00458 Haem peroxidase superfamily signature 314 329 2.7E-18 T 22-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 HRM2_RS00645 a79ca2780013171c0ff44e7b044f073a 720 PRINTS PR00458 Haem peroxidase superfamily signature 255 270 2.7E-18 T 22-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 HRM2_RS00645 a79ca2780013171c0ff44e7b044f073a 720 PRINTS PR00458 Haem peroxidase superfamily signature 86 100 2.7E-18 T 22-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 HRM2_RS00645 a79ca2780013171c0ff44e7b044f073a 720 PRINTS PR00458 Haem peroxidase superfamily signature 146 163 2.7E-18 T 22-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 HRM2_RS00645 a79ca2780013171c0ff44e7b044f073a 720 PRINTS PR00458 Haem peroxidase superfamily signature 164 176 2.7E-18 T 22-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 HRM2_RS00645 a79ca2780013171c0ff44e7b044f073a 720 Gene3D G3DSA:1.10.420.10 306 405 4.4E-47 T 22-04-2016 HRM2_RS00645 a79ca2780013171c0ff44e7b044f073a 720 Gene3D G3DSA:1.10.420.10 248 270 4.4E-47 T 22-04-2016 HRM2_RS00645 a79ca2780013171c0ff44e7b044f073a 720 Hamap MF_01961 Catalase-peroxidase [katG]. 3 720 39.835 T 22-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 HRM2_RS00645 a79ca2780013171c0ff44e7b044f073a 720 SUPERFAMILY SSF48113 428 719 4.57E-111 T 22-04-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 HRM2_RS00645 a79ca2780013171c0ff44e7b044f073a 720 Gene3D G3DSA:1.10.520.10 235 247 5.4E-76 T 22-04-2016 HRM2_RS00645 a79ca2780013171c0ff44e7b044f073a 720 Gene3D G3DSA:1.10.520.10 430 574 2.2E-53 T 22-04-2016 HRM2_RS00645 a79ca2780013171c0ff44e7b044f073a 720 Gene3D G3DSA:1.10.520.10 43 197 5.4E-76 T 22-04-2016 HRM2_RS00645 a79ca2780013171c0ff44e7b044f073a 720 Gene3D G3DSA:1.10.520.10 698 720 2.2E-53 T 22-04-2016 HRM2_RS00645 a79ca2780013171c0ff44e7b044f073a 720 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 6 719 0.0 T 22-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 HRM2_RS00645 a79ca2780013171c0ff44e7b044f073a 720 PANTHER PTHR30555 6 719 0.0 T 22-04-2016 HRM2_RS00645 a79ca2780013171c0ff44e7b044f073a 720 PANTHER PTHR30555:SF0 6 719 0.0 T 22-04-2016 HRM2_RS00645 a79ca2780013171c0ff44e7b044f073a 720 SUPERFAMILY SSF48113 15 427 3.24E-151 T 22-04-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 HRM2_RS00645 a79ca2780013171c0ff44e7b044f073a 720 Pfam PF00141 Peroxidase 67 394 6.6E-49 T 22-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 HRM2_RS00645 a79ca2780013171c0ff44e7b044f073a 720 Pfam PF00141 Peroxidase 402 694 4.2E-38 T 22-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 HRM2_RS00645 a79ca2780013171c0ff44e7b044f073a 720 Gene3D G3DSA:1.10.420.10 575 695 1.2E-44 T 22-04-2016 HRM2_RS18065 195e3089416b95fae28ea868e65fcd76 425 SUPERFAMILY SSF53901 305 425 9.31E-39 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS18065 195e3089416b95fae28ea868e65fcd76 425 PIRSF PIRSF000429 68 425 1.4E-116 T 22-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 HRM2_RS18065 195e3089416b95fae28ea868e65fcd76 425 PANTHER PTHR18919 74 425 7.0E-189 T 22-04-2016 HRM2_RS18065 195e3089416b95fae28ea868e65fcd76 425 PANTHER PTHR18919 1 42 7.0E-189 T 22-04-2016 HRM2_RS18065 195e3089416b95fae28ea868e65fcd76 425 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 116 134 - T 22-04-2016 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 Reactome: REACT_22258 HRM2_RS18065 195e3089416b95fae28ea868e65fcd76 425 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 75 424 1.4E-125 T 22-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 HRM2_RS18065 195e3089416b95fae28ea868e65fcd76 425 PANTHER PTHR18919:SF95 74 425 7.0E-189 T 22-04-2016 HRM2_RS18065 195e3089416b95fae28ea868e65fcd76 425 PANTHER PTHR18919:SF95 1 42 7.0E-189 T 22-04-2016 HRM2_RS18065 195e3089416b95fae28ea868e65fcd76 425 Pfam PF00108 Thiolase, N-terminal domain 75 295 3.2E-85 T 22-04-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 HRM2_RS18065 195e3089416b95fae28ea868e65fcd76 425 Pfam PF00108 Thiolase, N-terminal domain 4 45 2.7E-8 T 22-04-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 HRM2_RS18065 195e3089416b95fae28ea868e65fcd76 425 Pfam PF02803 Thiolase, C-terminal domain 304 425 1.0E-41 T 22-04-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 HRM2_RS18065 195e3089416b95fae28ea868e65fcd76 425 Gene3D G3DSA:3.40.47.10 3 46 3.8E-77 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS18065 195e3089416b95fae28ea868e65fcd76 425 Gene3D G3DSA:3.40.47.10 229 308 3.8E-77 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS18065 195e3089416b95fae28ea868e65fcd76 425 Gene3D G3DSA:3.40.47.10 79 155 3.8E-77 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS18065 195e3089416b95fae28ea868e65fcd76 425 SUPERFAMILY SSF53901 82 303 2.99E-78 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS18065 195e3089416b95fae28ea868e65fcd76 425 SUPERFAMILY SSF53901 3 44 2.99E-78 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS18065 195e3089416b95fae28ea868e65fcd76 425 ProSitePatterns PS00099 Thiolases active site. 407 420 - T 22-04-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 HRM2_RS18065 195e3089416b95fae28ea868e65fcd76 425 Gene3D G3DSA:3.40.47.10 178 228 9.8E-60 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS18065 195e3089416b95fae28ea868e65fcd76 425 Gene3D G3DSA:3.40.47.10 310 424 9.8E-60 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS23965 80f476315bbf1bbe6d25c58272ffc5d7 263 Pfam PF01226 Formate/nitrite transporter 8 255 1.6E-84 T 22-04-2016 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 HRM2_RS23965 80f476315bbf1bbe6d25c58272ffc5d7 263 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 80 89 - T 22-04-2016 IPR024002 Formate/nitrite transporter, conserved site HRM2_RS23965 80f476315bbf1bbe6d25c58272ffc5d7 263 Gene3D G3DSA:1.20.1080.10 25 259 2.1E-90 T 22-04-2016 IPR023271 Aquaporin-like HRM2_RS23965 80f476315bbf1bbe6d25c58272ffc5d7 263 PANTHER PTHR30520 1 257 3.8E-110 T 22-04-2016 HRM2_RS23965 80f476315bbf1bbe6d25c58272ffc5d7 263 PANTHER PTHR30520:SF0 1 257 3.8E-110 T 22-04-2016 HRM2_RS23965 80f476315bbf1bbe6d25c58272ffc5d7 263 TIGRFAM TIGR00790 fnt: formate/nitrite transporter 25 257 4.2E-83 T 22-04-2016 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 HRM2_RS03960 1aace4386e03e6828dd757bc2d87a836 271 Pfam PF00440 Bacterial regulatory proteins, tetR family 83 125 5.3E-12 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS03960 1aace4386e03e6828dd757bc2d87a836 271 Pfam PF16925 Bacterial transcriptional repressor C-terminal 151 262 1.1E-18 T 22-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal HRM2_RS03960 1aace4386e03e6828dd757bc2d87a836 271 SUPERFAMILY SSF46689 77 148 2.46E-15 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS03960 1aace4386e03e6828dd757bc2d87a836 271 PANTHER PTHR30055:SF20 66 268 1.4E-42 T 22-04-2016 HRM2_RS03960 1aace4386e03e6828dd757bc2d87a836 271 PANTHER PTHR30055 66 268 1.4E-42 T 22-04-2016 HRM2_RS03960 1aace4386e03e6828dd757bc2d87a836 271 Gene3D G3DSA:1.10.357.10 78 266 3.9E-44 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HRM2_RS03960 1aace4386e03e6828dd757bc2d87a836 271 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 104 127 6.8E-5 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS03960 1aace4386e03e6828dd757bc2d87a836 271 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 83 96 6.8E-5 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS03960 1aace4386e03e6828dd757bc2d87a836 271 SUPERFAMILY SSF48498 150 264 7.86E-23 T 22-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal HRM2_RS14810 f5b56043d72123baddeb6626f29c18ee 425 Pfam PF00005 ABC transporter 44 176 7.0E-21 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS14810 f5b56043d72123baddeb6626f29c18ee 425 PANTHER PTHR24220 30 261 6.6E-101 T 22-04-2016 HRM2_RS14810 f5b56043d72123baddeb6626f29c18ee 425 Gene3D G3DSA:2.70.50.60 277 412 1.3E-21 T 22-04-2016 HRM2_RS14810 f5b56043d72123baddeb6626f29c18ee 425 SUPERFAMILY SSF52540 34 237 5.33E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14810 f5b56043d72123baddeb6626f29c18ee 425 Pfam PF14524 Wzt C-terminal domain 278 412 2.2E-24 T 22-04-2016 IPR029439 Wzt, C-terminal HRM2_RS14810 f5b56043d72123baddeb6626f29c18ee 425 SMART SM00382 53 223 6.5E-15 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS14810 f5b56043d72123baddeb6626f29c18ee 425 PANTHER PTHR24220:SF117 30 261 6.6E-101 T 22-04-2016 HRM2_RS14810 f5b56043d72123baddeb6626f29c18ee 425 Gene3D G3DSA:3.40.50.300 6 239 9.5E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14685 f9f7f7104568b8542257b4d145838f39 96 SUPERFAMILY SSF47781 27 92 1.02E-23 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 HRM2_RS14685 f9f7f7104568b8542257b4d145838f39 96 Gene3D G3DSA:1.10.150.280 11 92 3.8E-18 T 22-04-2016 HRM2_RS14685 f9f7f7104568b8542257b4d145838f39 96 Pfam PF12836 Helix-hairpin-helix motif 29 88 8.0E-22 T 22-04-2016 HRM2_RS14685 f9f7f7104568b8542257b4d145838f39 96 PANTHER PTHR21180 28 92 2.8E-15 T 22-04-2016 HRM2_RS14685 f9f7f7104568b8542257b4d145838f39 96 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 30 92 2.1E-17 T 22-04-2016 IPR004509 Competence protein ComEA, helix-hairpin-helix domain HRM2_RS22245 9f02cd33d197bb8264bee7de221d4690 111 PIRSF PIRSF029883 7 111 7.9E-27 T 22-04-2016 IPR025499 Pectin degradation protein KdgF UniPathway: UPA00545 HRM2_RS22245 9f02cd33d197bb8264bee7de221d4690 111 PANTHER PTHR40112 1 106 1.1E-20 T 22-04-2016 HRM2_RS22245 9f02cd33d197bb8264bee7de221d4690 111 Pfam PF07883 Cupin domain 34 92 2.2E-12 T 22-04-2016 IPR013096 Cupin 2, conserved barrel HRM2_RS22245 9f02cd33d197bb8264bee7de221d4690 111 SUPERFAMILY SSF51182 22 106 2.33E-20 T 22-04-2016 IPR011051 RmlC-like cupin domain HRM2_RS22245 9f02cd33d197bb8264bee7de221d4690 111 PANTHER PTHR40112:SF1 1 106 1.1E-20 T 22-04-2016 HRM2_RS22245 9f02cd33d197bb8264bee7de221d4690 111 Gene3D G3DSA:2.60.120.10 11 107 1.6E-24 T 22-04-2016 IPR014710 RmlC-like jelly roll fold HRM2_RS08480 9b80ec11ba3c4acbdd1149bfc3f6d8c9 224 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 HRM2_RS08480 9b80ec11ba3c4acbdd1149bfc3f6d8c9 224 Hamap MF_00235 Adenylate kinase [adk]. 1 222 31.786 T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 HRM2_RS08480 9b80ec11ba3c4acbdd1149bfc3f6d8c9 224 Gene3D G3DSA:3.40.50.300 1 223 6.8E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08480 9b80ec11ba3c4acbdd1149bfc3f6d8c9 224 TIGRFAM TIGR01351 adk: adenylate kinase 2 190 9.0E-51 T 22-04-2016 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 HRM2_RS08480 9b80ec11ba3c4acbdd1149bfc3f6d8c9 224 Pfam PF00406 Adenylate kinase 6 183 2.0E-41 T 22-04-2016 HRM2_RS08480 9b80ec11ba3c4acbdd1149bfc3f6d8c9 224 PANTHER PTHR23359 1 180 1.7E-46 T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 HRM2_RS08480 9b80ec11ba3c4acbdd1149bfc3f6d8c9 224 PRINTS PR00094 Adenylate kinase signature 81 97 7.3E-17 T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 HRM2_RS08480 9b80ec11ba3c4acbdd1149bfc3f6d8c9 224 PRINTS PR00094 Adenylate kinase signature 32 46 7.3E-17 T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 HRM2_RS08480 9b80ec11ba3c4acbdd1149bfc3f6d8c9 224 PRINTS PR00094 Adenylate kinase signature 4 17 7.3E-17 T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 HRM2_RS08480 9b80ec11ba3c4acbdd1149bfc3f6d8c9 224 PRINTS PR00094 Adenylate kinase signature 162 177 7.3E-17 T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 HRM2_RS08480 9b80ec11ba3c4acbdd1149bfc3f6d8c9 224 SUPERFAMILY SSF52540 1 172 2.27E-30 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14365 10c31712bf392f06526280e87bad009f 390 SUPERFAMILY SSF54373 220 324 2.35E-13 T 22-04-2016 HRM2_RS14365 10c31712bf392f06526280e87bad009f 390 Gene3D G3DSA:3.50.50.60 3 83 1.0E-60 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS14365 10c31712bf392f06526280e87bad009f 390 Gene3D G3DSA:3.50.50.60 141 219 1.0E-60 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS14365 10c31712bf392f06526280e87bad009f 390 Gene3D G3DSA:3.50.50.60 324 383 1.0E-60 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS14365 10c31712bf392f06526280e87bad009f 390 SUPERFAMILY SSF51905 6 220 1.81E-59 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS14365 10c31712bf392f06526280e87bad009f 390 SUPERFAMILY SSF51905 324 382 1.81E-59 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS14365 10c31712bf392f06526280e87bad009f 390 PANTHER PTHR13847 3 384 1.8E-85 T 22-04-2016 HRM2_RS14365 10c31712bf392f06526280e87bad009f 390 Gene3D G3DSA:3.30.9.10 88 140 1.4E-13 T 22-04-2016 HRM2_RS14365 10c31712bf392f06526280e87bad009f 390 Gene3D G3DSA:3.30.9.10 220 323 1.4E-13 T 22-04-2016 HRM2_RS14365 10c31712bf392f06526280e87bad009f 390 PANTHER PTHR13847:SF180 3 384 1.8E-85 T 22-04-2016 HRM2_RS14365 10c31712bf392f06526280e87bad009f 390 Pfam PF01266 FAD dependent oxidoreductase 8 363 3.5E-69 T 22-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 HRM2_RS02525 92aa350f0807596fc014a3be87303216 442 Gene3D G3DSA:3.40.190.10 146 361 3.0E-32 T 22-04-2016 HRM2_RS02525 92aa350f0807596fc014a3be87303216 442 Pfam PF13416 Bacterial extracellular solute-binding protein 46 371 1.6E-37 T 22-04-2016 HRM2_RS02525 92aa350f0807596fc014a3be87303216 442 SUPERFAMILY SSF53850 27 429 1.43E-67 T 22-04-2016 HRM2_RS02525 92aa350f0807596fc014a3be87303216 442 PANTHER PTHR30061 25 442 1.3E-117 T 22-04-2016 HRM2_RS02525 92aa350f0807596fc014a3be87303216 442 PANTHER PTHR30061:SF7 25 442 1.3E-117 T 22-04-2016 HRM2_RS08680 c3881cfed326056748c586ae59f5174e 150 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 7 149 45.187 T 22-04-2016 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 HRM2_RS08680 c3881cfed326056748c586ae59f5174e 150 SUPERFAMILY SSF53927 2 149 7.86E-52 T 22-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 HRM2_RS08680 c3881cfed326056748c586ae59f5174e 150 PANTHER PTHR11079:SF72 3 149 7.5E-42 T 22-04-2016 HRM2_RS08680 c3881cfed326056748c586ae59f5174e 150 Gene3D G3DSA:3.40.140.10 2 147 6.9E-54 T 22-04-2016 HRM2_RS08680 c3881cfed326056748c586ae59f5174e 150 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 90 - T 22-04-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 HRM2_RS08680 c3881cfed326056748c586ae59f5174e 150 PANTHER PTHR11079 3 149 7.5E-42 T 22-04-2016 HRM2_RS08680 c3881cfed326056748c586ae59f5174e 150 Pfam PF14437 MafB19-like deaminase 2 148 2.4E-27 T 22-04-2016 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 HRM2_RS18485 d045144b92a35cd4af9afff37d8605f6 431 SUPERFAMILY SSF103473 28 421 9.55E-34 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS18485 d045144b92a35cd4af9afff37d8605f6 431 PANTHER PTHR12778 30 416 3.4E-96 T 22-04-2016 HRM2_RS18485 d045144b92a35cd4af9afff37d8605f6 431 Gene3D G3DSA:1.20.1250.20 236 424 6.9E-14 T 22-04-2016 HRM2_RS18485 d045144b92a35cd4af9afff37d8605f6 431 Pfam PF07690 Major Facilitator Superfamily 49 384 7.0E-17 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS18485 d045144b92a35cd4af9afff37d8605f6 431 Gene3D G3DSA:1.20.1250.20 31 216 1.9E-10 T 22-04-2016 HRM2_RS21890 0c203f84ce699f626bf9c21726954d18 282 Gene3D G3DSA:1.10.443.10 179 276 3.0E-14 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS21890 0c203f84ce699f626bf9c21726954d18 282 SUPERFAMILY SSF56349 69 277 1.8E-23 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HRM2_RS21890 0c203f84ce699f626bf9c21726954d18 282 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 78 152 1.6E-7 T 22-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 HRM2_RS21890 0c203f84ce699f626bf9c21726954d18 282 Gene3D G3DSA:1.10.150.130 76 157 5.2E-8 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal HRM2_RS21890 0c203f84ce699f626bf9c21726954d18 282 PANTHER PTHR30349 61 277 2.1E-18 T 22-04-2016 HRM2_RS21890 0c203f84ce699f626bf9c21726954d18 282 Pfam PF00589 Phage integrase family 180 275 2.3E-8 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS21890 0c203f84ce699f626bf9c21726954d18 282 PANTHER PTHR30349:SF5 61 277 2.1E-18 T 22-04-2016 HRM2_RS09155 923ef6c180c3137aa1cad07f77929916 290 PANTHER PTHR30193 1 279 1.4E-71 T 22-04-2016 HRM2_RS09155 923ef6c180c3137aa1cad07f77929916 290 Gene3D G3DSA:1.10.3720.10 56 282 2.4E-45 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS09155 923ef6c180c3137aa1cad07f77929916 290 SUPERFAMILY SSF161098 51 277 9.68E-47 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS09155 923ef6c180c3137aa1cad07f77929916 290 PANTHER PTHR30193:SF6 1 279 1.4E-71 T 22-04-2016 HRM2_RS09155 923ef6c180c3137aa1cad07f77929916 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 278 1.2E-14 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS20835 88c45ffee92e744c00f254f8facc6f3b 249 Gene3D G3DSA:1.10.10.10 2 53 2.0E-10 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS20835 88c45ffee92e744c00f254f8facc6f3b 249 PANTHER PTHR30363 1 247 1.6E-98 T 22-04-2016 HRM2_RS20835 88c45ffee92e744c00f254f8facc6f3b 249 Pfam PF08220 DeoR-like helix-turn-helix domain 4 59 2.3E-18 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 HRM2_RS20835 88c45ffee92e744c00f254f8facc6f3b 249 SUPERFAMILY SSF46785 2 70 2.43E-14 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS20835 88c45ffee92e744c00f254f8facc6f3b 249 SMART SM00420 4 56 2.1E-19 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 HRM2_RS20835 88c45ffee92e744c00f254f8facc6f3b 249 ProSitePatterns PS00894 DeoR-type HTH domain signature. 4 38 - T 22-04-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 HRM2_RS20835 88c45ffee92e744c00f254f8facc6f3b 249 SMART SM01134 70 231 1.0E-67 T 22-04-2016 HRM2_RS20835 88c45ffee92e744c00f254f8facc6f3b 249 SUPERFAMILY SSF100950 73 232 9.21E-28 T 22-04-2016 HRM2_RS20835 88c45ffee92e744c00f254f8facc6f3b 249 Pfam PF00455 DeoR C terminal sensor domain 74 229 4.9E-51 T 22-04-2016 IPR014036 DeoR C-terminal sensor domain HRM2_RS20835 88c45ffee92e744c00f254f8facc6f3b 249 Gene3D G3DSA:3.40.50.1360 73 212 2.9E-10 T 22-04-2016 HRM2_RS20835 88c45ffee92e744c00f254f8facc6f3b 249 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 36 54 7.4E-10 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 HRM2_RS20835 88c45ffee92e744c00f254f8facc6f3b 249 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 22 36 7.4E-10 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 HRM2_RS20835 88c45ffee92e744c00f254f8facc6f3b 249 PANTHER PTHR30363:SF1 1 247 1.6E-98 T 22-04-2016 HRM2_RS11080 42721d50f50af7e765d57772523a0d33 545 SUPERFAMILY SSF56762 1 530 1.44E-174 T 22-04-2016 IPR029014 NiFe hydrogenase-like HRM2_RS11080 42721d50f50af7e765d57772523a0d33 545 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 521 530 - T 22-04-2016 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 HRM2_RS11080 42721d50f50af7e765d57772523a0d33 545 PANTHER PTHR11993 185 248 6.2E-168 T 22-04-2016 HRM2_RS11080 42721d50f50af7e765d57772523a0d33 545 PANTHER PTHR11993 3 116 6.2E-168 T 22-04-2016 HRM2_RS11080 42721d50f50af7e765d57772523a0d33 545 PANTHER PTHR11993 337 537 6.2E-168 T 22-04-2016 HRM2_RS11080 42721d50f50af7e765d57772523a0d33 545 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 39 64 - T 22-04-2016 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 HRM2_RS11080 42721d50f50af7e765d57772523a0d33 545 Pfam PF00374 Nickel-dependent hydrogenase 39 530 1.6E-214 T 22-04-2016 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 HRM2_RS11080 42721d50f50af7e765d57772523a0d33 545 PANTHER PTHR11993:SF11 185 248 6.2E-168 T 22-04-2016 HRM2_RS11080 42721d50f50af7e765d57772523a0d33 545 PANTHER PTHR11993:SF11 3 116 6.2E-168 T 22-04-2016 HRM2_RS11080 42721d50f50af7e765d57772523a0d33 545 PANTHER PTHR11993:SF11 337 537 6.2E-168 T 22-04-2016 HRM2_RS11080 42721d50f50af7e765d57772523a0d33 545 Gene3D G3DSA:1.10.645.10 1 530 2.3E-214 T 22-04-2016 IPR029014 NiFe hydrogenase-like HRM2_RS00325 df552ebc6ada08f2acdc205dc0e64aed 383 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 39 374 7.0E-45 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 HRM2_RS00325 df552ebc6ada08f2acdc205dc0e64aed 383 PANTHER PTHR30469 1 360 3.0E-44 T 22-04-2016 HRM2_RS00325 df552ebc6ada08f2acdc205dc0e64aed 383 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 59 280 4.1E-17 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain HRM2_RS00325 df552ebc6ada08f2acdc205dc0e64aed 383 Gene3D G3DSA:2.40.50.100 65 97 6.3E-14 T 22-04-2016 HRM2_RS00325 df552ebc6ada08f2acdc205dc0e64aed 383 Gene3D G3DSA:2.40.50.100 186 218 6.3E-14 T 22-04-2016 HRM2_RS00325 df552ebc6ada08f2acdc205dc0e64aed 383 SUPERFAMILY SSF111369 56 288 3.53E-12 T 22-04-2016 HRM2_RS21055 77b518ac5ec0290d89cc876f174aaa4e 721 PANTHER PTHR11649 272 550 1.1E-223 T 22-04-2016 HRM2_RS21055 77b518ac5ec0290d89cc876f174aaa4e 721 PANTHER PTHR11649 589 719 1.1E-223 T 22-04-2016 HRM2_RS21055 77b518ac5ec0290d89cc876f174aaa4e 721 PANTHER PTHR11649 5 145 1.1E-223 T 22-04-2016 HRM2_RS21055 77b518ac5ec0290d89cc876f174aaa4e 721 Pfam PF07670 Nucleoside recognition 356 452 1.6E-13 T 22-04-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 HRM2_RS21055 77b518ac5ec0290d89cc876f174aaa4e 721 Pfam PF07670 Nucleoside recognition 521 691 1.5E-23 T 22-04-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 HRM2_RS21055 77b518ac5ec0290d89cc876f174aaa4e 721 Pfam PF07664 Ferrous iron transport protein B C terminus 464 516 9.0E-19 T 22-04-2016 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 HRM2_RS21055 77b518ac5ec0290d89cc876f174aaa4e 721 PANTHER PTHR11649:SF37 272 550 1.1E-223 T 22-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 HRM2_RS21055 77b518ac5ec0290d89cc876f174aaa4e 721 PANTHER PTHR11649:SF37 589 719 1.1E-223 T 22-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 HRM2_RS21055 77b518ac5ec0290d89cc876f174aaa4e 721 PANTHER PTHR11649:SF37 5 145 1.1E-223 T 22-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 HRM2_RS21055 77b518ac5ec0290d89cc876f174aaa4e 721 Pfam PF02421 Ferrous iron transport protein B 4 157 1.7E-68 T 22-04-2016 IPR011619 Ferrous iron transport protein B, N-terminal GO:0005525|GO:0015093|GO:0015684|GO:0016021 HRM2_RS21055 77b518ac5ec0290d89cc876f174aaa4e 721 Gene3D G3DSA:3.40.50.300 5 159 1.3E-32 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21055 77b518ac5ec0290d89cc876f174aaa4e 721 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 3.7E-6 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS21055 77b518ac5ec0290d89cc876f174aaa4e 721 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 3.7E-6 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS21055 77b518ac5ec0290d89cc876f174aaa4e 721 SUPERFAMILY SSF52540 5 162 3.86E-39 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21055 77b518ac5ec0290d89cc876f174aaa4e 721 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 9 687 4.8E-173 T 22-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 HRM2_RS15455 3f062f391d216c652024958b293f22fd 416 Gene3D G3DSA:3.90.1150.10 281 410 1.1E-52 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS15455 3f062f391d216c652024958b293f22fd 416 PANTHER PTHR11680 6 415 9.1E-239 T 22-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 HRM2_RS15455 3f062f391d216c652024958b293f22fd 416 PIRSF PIRSF000412 1 414 5.4E-165 T 22-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 HRM2_RS15455 3f062f391d216c652024958b293f22fd 416 Pfam PF00464 Serine hydroxymethyltransferase 7 382 1.5E-167 T 22-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 HRM2_RS15455 3f062f391d216c652024958b293f22fd 416 Gene3D G3DSA:3.40.640.10 35 280 5.4E-103 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS15455 3f062f391d216c652024958b293f22fd 416 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 5 410 52.508 T 22-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 HRM2_RS15455 3f062f391d216c652024958b293f22fd 416 SUPERFAMILY SSF53383 6 410 5.84E-177 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS15455 3f062f391d216c652024958b293f22fd 416 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 220 236 - T 22-04-2016 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 HRM2_RS01580 b8df4798b70f0aa94ccaa46c71cce714 530 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 8 25 - T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS01580 b8df4798b70f0aa94ccaa46c71cce714 530 SUPERFAMILY SSF51905 3 311 2.05E-37 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS01580 b8df4798b70f0aa94ccaa46c71cce714 530 Gene3D G3DSA:3.50.50.60 444 475 3.2E-36 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS01580 b8df4798b70f0aa94ccaa46c71cce714 530 Gene3D G3DSA:3.50.50.60 1 284 3.2E-36 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS01580 b8df4798b70f0aa94ccaa46c71cce714 530 PANTHER PTHR11985 1 514 7.1E-159 T 22-04-2016 HRM2_RS01580 b8df4798b70f0aa94ccaa46c71cce714 530 PANTHER PTHR11985:SF14 1 514 7.1E-159 T 22-04-2016 HRM2_RS01580 b8df4798b70f0aa94ccaa46c71cce714 530 Pfam PF01266 FAD dependent oxidoreductase 5 340 4.1E-42 T 22-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 HRM2_RS01580 b8df4798b70f0aa94ccaa46c71cce714 530 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 16 26 2.4E-19 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS01580 b8df4798b70f0aa94ccaa46c71cce714 530 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 76 88 2.4E-19 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS01580 b8df4798b70f0aa94ccaa46c71cce714 530 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 3 15 2.4E-19 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS01580 b8df4798b70f0aa94ccaa46c71cce714 530 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 337 349 2.4E-19 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS01580 b8df4798b70f0aa94ccaa46c71cce714 530 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 303 309 2.4E-19 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS01580 b8df4798b70f0aa94ccaa46c71cce714 530 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 32 44 2.4E-19 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS20065 84241ec96bf35547c2bbdac61fc8a399 65 Gene3D G3DSA:3.30.70.20 3 63 3.1E-9 T 22-04-2016 HRM2_RS20065 84241ec96bf35547c2bbdac61fc8a399 65 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 12 23 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS20065 84241ec96bf35547c2bbdac61fc8a399 65 SUPERFAMILY SSF54862 5 61 1.31E-6 T 22-04-2016 HRM2_RS20065 84241ec96bf35547c2bbdac61fc8a399 65 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 60 1.3E-7 T 22-04-2016 HRM2_RS21295 c74f419de22f60f59494998992957759 215 Gene3D G3DSA:3.30.70.240 149 202 1.8E-4 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain HRM2_RS21295 c74f419de22f60f59494998992957759 215 Gene3D G3DSA:3.30.230.30 27 144 4.8E-42 T 22-04-2016 IPR001498 Impact, N-terminal HRM2_RS21295 c74f419de22f60f59494998992957759 215 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 93 122 - T 22-04-2016 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site HRM2_RS21295 c74f419de22f60f59494998992957759 215 PANTHER PTHR16301 16 202 2.8E-49 T 22-04-2016 IPR023582 Impact family HRM2_RS21295 c74f419de22f60f59494998992957759 215 SUPERFAMILY SSF54980 150 205 1.22E-5 T 22-04-2016 IPR009022 Elongation factor G, III-V domain HRM2_RS21295 c74f419de22f60f59494998992957759 215 Pfam PF01205 Uncharacterized protein family UPF0029 33 137 4.0E-29 T 22-04-2016 IPR001498 Impact, N-terminal HRM2_RS21295 c74f419de22f60f59494998992957759 215 SUPERFAMILY SSF54211 27 144 6.83E-38 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS21295 c74f419de22f60f59494998992957759 215 PANTHER PTHR16301:SF0 16 202 2.8E-49 T 22-04-2016 HRM2_RS21295 c74f419de22f60f59494998992957759 215 Pfam PF09186 Domain of unknown function (DUF1949) 154 202 2.8E-7 T 22-04-2016 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal HRM2_RS08430 e5aba1d20cb98340a01203cad09895e7 764 SUPERFAMILY SSF52540 368 669 1.3E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08430 e5aba1d20cb98340a01203cad09895e7 764 Pfam PF01580 FtsK/SpoIIIE family 395 599 2.9E-61 T 22-04-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 HRM2_RS08430 e5aba1d20cb98340a01203cad09895e7 764 PANTHER PTHR22683:SF41 289 760 1.7E-222 T 22-04-2016 HRM2_RS08430 e5aba1d20cb98340a01203cad09895e7 764 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 2 172 2.5E-28 T 22-04-2016 IPR025199 DNA translocase FtsK, 4TM region HRM2_RS08430 e5aba1d20cb98340a01203cad09895e7 764 PANTHER PTHR22683 289 760 1.7E-222 T 22-04-2016 HRM2_RS08430 e5aba1d20cb98340a01203cad09895e7 764 SMART SM00382 430 620 3.7E-5 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS08430 e5aba1d20cb98340a01203cad09895e7 764 Gene3D G3DSA:3.40.50.300 368 665 4.1E-92 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08430 e5aba1d20cb98340a01203cad09895e7 764 SMART SM00843 697 762 1.4E-37 T 22-04-2016 IPR018541 FtsK gamma domain HRM2_RS08430 e5aba1d20cb98340a01203cad09895e7 764 SUPERFAMILY SSF46785 698 761 1.63E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS08430 e5aba1d20cb98340a01203cad09895e7 764 Pfam PF09397 Ftsk gamma domain 699 759 2.5E-28 T 22-04-2016 IPR018541 FtsK gamma domain HRM2_RS10845 7672057a0549d7c88aa9944418a9d00b 225 SUPERFAMILY SSF56059 14 224 4.24E-42 T 22-04-2016 HRM2_RS10845 7672057a0549d7c88aa9944418a9d00b 225 Pfam PF13549 ATP-grasp domain 7 222 1.1E-65 T 22-04-2016 HRM2_RS10845 7672057a0549d7c88aa9944418a9d00b 225 Gene3D G3DSA:3.30.1490.20 26 101 1.1E-5 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HRM2_RS10845 7672057a0549d7c88aa9944418a9d00b 225 PANTHER PTHR11117 2 225 4.9E-60 T 22-04-2016 HRM2_RS10845 7672057a0549d7c88aa9944418a9d00b 225 PANTHER PTHR11117:SF8 2 225 4.9E-60 T 22-04-2016 HRM2_RS10845 7672057a0549d7c88aa9944418a9d00b 225 Gene3D G3DSA:3.30.470.20 102 222 6.0E-9 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS14005 bca59b1e8203172fb16ba1cd38fef972 208 Pfam PF02589 Uncharacterised ACR, YkgG family COG1556 11 205 1.1E-27 T 22-04-2016 IPR003741 LUD domain HRM2_RS14005 bca59b1e8203172fb16ba1cd38fef972 208 PANTHER PTHR32479 102 207 5.1E-19 T 22-04-2016 HRM2_RS14005 bca59b1e8203172fb16ba1cd38fef972 208 Gene3D G3DSA:3.40.50.10420 4 205 6.5E-37 T 22-04-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain HRM2_RS14005 bca59b1e8203172fb16ba1cd38fef972 208 PANTHER PTHR32479:SF11 102 207 5.1E-19 T 22-04-2016 HRM2_RS14005 bca59b1e8203172fb16ba1cd38fef972 208 SUPERFAMILY SSF100950 89 206 6.7E-30 T 22-04-2016 HRM2_RS14005 bca59b1e8203172fb16ba1cd38fef972 208 SUPERFAMILY SSF100950 4 53 6.7E-30 T 22-04-2016 HRM2_RS02665 bbea1782a7027ae63f041af83a631a07 697 Pfam PF13380 CoA binding domain 9 131 1.4E-24 T 22-04-2016 IPR003781 CoA-binding GO:0048037 HRM2_RS02665 bbea1782a7027ae63f041af83a631a07 697 SUPERFAMILY SSF51735 2 128 4.47E-38 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS02665 bbea1782a7027ae63f041af83a631a07 697 SUPERFAMILY SSF52210 300 458 2.88E-28 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS02665 bbea1782a7027ae63f041af83a631a07 697 SUPERFAMILY SSF56059 490 696 1.36E-35 T 22-04-2016 HRM2_RS02665 bbea1782a7027ae63f041af83a631a07 697 Gene3D G3DSA:3.40.50.261 300 449 3.0E-9 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS02665 bbea1782a7027ae63f041af83a631a07 697 PANTHER PTHR33303 1 439 3.5E-156 T 22-04-2016 HRM2_RS02665 bbea1782a7027ae63f041af83a631a07 697 PANTHER PTHR33303 465 696 3.5E-156 T 22-04-2016 HRM2_RS02665 bbea1782a7027ae63f041af83a631a07 697 PANTHER PTHR33303:SF3 1 439 3.5E-156 T 22-04-2016 HRM2_RS02665 bbea1782a7027ae63f041af83a631a07 697 PANTHER PTHR33303:SF3 465 696 3.5E-156 T 22-04-2016 HRM2_RS02665 bbea1782a7027ae63f041af83a631a07 697 Gene3D G3DSA:3.40.50.261 127 288 3.9E-23 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS02665 bbea1782a7027ae63f041af83a631a07 697 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 154 290 1.9E-43 T 22-04-2016 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain HRM2_RS02665 bbea1782a7027ae63f041af83a631a07 697 SUPERFAMILY SSF52210 152 289 9.16E-31 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS02665 bbea1782a7027ae63f041af83a631a07 697 Gene3D G3DSA:3.40.50.720 1 126 1.5E-36 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS02665 bbea1782a7027ae63f041af83a631a07 697 Gene3D G3DSA:3.30.470.20 494 604 4.0E-7 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS02665 bbea1782a7027ae63f041af83a631a07 697 SMART SM00881 4 98 4.3E-31 T 22-04-2016 IPR003781 CoA-binding GO:0048037 HRM2_RS02665 bbea1782a7027ae63f041af83a631a07 697 Pfam PF13549 ATP-grasp domain 484 695 2.9E-54 T 22-04-2016 HRM2_RS21730 b11f4103637ee2ec6b75bf9adb4279f3 538 SMART SM01222 3 180 5.9E-114 T 22-04-2016 IPR012886 Formiminotransferase, N-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|UniPathway: UPA00193|UniPathway: UPA00379 HRM2_RS21730 b11f4103637ee2ec6b75bf9adb4279f3 538 Gene3D G3DSA:3.30.990.10 2 181 7.0E-72 T 22-04-2016 IPR012886 Formiminotransferase, N-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|UniPathway: UPA00193|UniPathway: UPA00379 HRM2_RS21730 b11f4103637ee2ec6b75bf9adb4279f3 538 SUPERFAMILY SSF55116 181 326 4.18E-51 T 22-04-2016 IPR022384 Formiminotransferase subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|UniPathway: UPA00193|UniPathway: UPA00379 HRM2_RS21730 b11f4103637ee2ec6b75bf9adb4279f3 538 Pfam PF02971 Formiminotransferase domain 181 324 5.9E-63 T 22-04-2016 IPR013802 Formiminotransferase, C-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|UniPathway: UPA00193|UniPathway: UPA00379 HRM2_RS21730 b11f4103637ee2ec6b75bf9adb4279f3 538 SMART SM01221 181 325 1.6E-82 T 22-04-2016 IPR013802 Formiminotransferase, C-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|UniPathway: UPA00193|UniPathway: UPA00379 HRM2_RS21730 b11f4103637ee2ec6b75bf9adb4279f3 538 TIGRFAM TIGR02024 FtcD: glutamate formiminotransferase 1 291 4.4E-119 T 22-04-2016 IPR004227 Formiminotransferase catalytic domain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|UniPathway: UPA00193|UniPathway: UPA00379 HRM2_RS21730 b11f4103637ee2ec6b75bf9adb4279f3 538 PANTHER PTHR12234:SF0 1 498 5.4E-284 T 22-04-2016 HRM2_RS21730 b11f4103637ee2ec6b75bf9adb4279f3 538 Pfam PF07837 Formiminotransferase domain, N-terminal subdomain 4 179 8.4E-69 T 22-04-2016 IPR012886 Formiminotransferase, N-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|UniPathway: UPA00193|UniPathway: UPA00379 HRM2_RS21730 b11f4103637ee2ec6b75bf9adb4279f3 538 Pfam PF04961 Formiminotransferase-cyclodeaminase 339 517 2.5E-66 T 22-04-2016 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00379 HRM2_RS21730 b11f4103637ee2ec6b75bf9adb4279f3 538 PANTHER PTHR12234 1 498 5.4E-284 T 22-04-2016 HRM2_RS21730 b11f4103637ee2ec6b75bf9adb4279f3 538 SUPERFAMILY SSF101262 334 537 3.27E-57 T 22-04-2016 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00379 HRM2_RS21730 b11f4103637ee2ec6b75bf9adb4279f3 538 SUPERFAMILY SSF55116 3 180 8.63E-67 T 22-04-2016 IPR022384 Formiminotransferase subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|UniPathway: UPA00193|UniPathway: UPA00379 HRM2_RS21730 b11f4103637ee2ec6b75bf9adb4279f3 538 Gene3D G3DSA:3.30.70.670 182 325 1.7E-55 T 22-04-2016 IPR013802 Formiminotransferase, C-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|UniPathway: UPA00193|UniPathway: UPA00379 HRM2_RS20745 e53cb1b063fe6fbbe4468c37e1a9cb4e 357 Pfam PF00561 alpha/beta hydrolase fold 83 335 1.4E-20 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HRM2_RS20745 e53cb1b063fe6fbbe4468c37e1a9cb4e 357 TIGRFAM TIGR01836 PHA_synth_III_C: poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit 11 356 2.5E-120 T 22-04-2016 IPR010125 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit GO:0016746|GO:0042619 KEGG: 00061+2.3.1.-|KEGG: 00253+2.3.1.-|KEGG: 00261+2.3.1.-|KEGG: 00310+2.3.1.-|KEGG: 00330+2.3.1.-|KEGG: 00332+2.3.1.-|KEGG: 00340+2.3.1.-|KEGG: 00350+2.3.1.-|KEGG: 00564+2.3.1.-|KEGG: 00565+2.3.1.-|KEGG: 00604+2.3.1.-|KEGG: 00623+2.3.1.-|KEGG: 00626+2.3.1.-|KEGG: 00627+2.3.1.-|KEGG: 00642+2.3.1.-|KEGG: 00650+2.3.1.-|KEGG: 00680+2.3.1.-|KEGG: 00903+2.3.1.-|KEGG: 00904+2.3.1.-|KEGG: 00906+2.3.1.-|KEGG: 00940+2.3.1.-|KEGG: 00942+2.3.1.-|KEGG: 00950+2.3.1.-|KEGG: 00960+2.3.1.-|KEGG: 00965+2.3.1.-|UniPathway: UPA00917 HRM2_RS20745 e53cb1b063fe6fbbe4468c37e1a9cb4e 357 Gene3D G3DSA:3.40.50.1820 52 356 2.0E-45 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS20745 e53cb1b063fe6fbbe4468c37e1a9cb4e 357 SUPERFAMILY SSF53474 54 354 1.72E-32 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS20745 e53cb1b063fe6fbbe4468c37e1a9cb4e 357 PANTHER PTHR36837 6 357 7.4E-105 T 22-04-2016 HRM2_RS03285 38c27cc5968896a98591c699b3661612 716 Pfam PF13549 ATP-grasp domain 492 712 1.1E-76 T 22-04-2016 HRM2_RS03285 38c27cc5968896a98591c699b3661612 716 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 155 295 2.4E-52 T 22-04-2016 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain HRM2_RS03285 38c27cc5968896a98591c699b3661612 716 Pfam PF13380 CoA binding domain 12 137 6.6E-22 T 22-04-2016 IPR003781 CoA-binding GO:0048037 HRM2_RS03285 38c27cc5968896a98591c699b3661612 716 PANTHER PTHR11117 28 716 4.9E-258 T 22-04-2016 HRM2_RS03285 38c27cc5968896a98591c699b3661612 716 Gene3D G3DSA:3.40.50.261 310 460 1.4E-18 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS03285 38c27cc5968896a98591c699b3661612 716 PANTHER PTHR11117:SF8 28 716 4.9E-258 T 22-04-2016 HRM2_RS03285 38c27cc5968896a98591c699b3661612 716 SUPERFAMILY SSF52210 311 468 2.09E-41 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS03285 38c27cc5968896a98591c699b3661612 716 Gene3D G3DSA:3.40.50.720 2 132 3.6E-36 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS03285 38c27cc5968896a98591c699b3661612 716 SMART SM00881 7 102 2.0E-28 T 22-04-2016 IPR003781 CoA-binding GO:0048037 HRM2_RS03285 38c27cc5968896a98591c699b3661612 716 SUPERFAMILY SSF51735 2 140 5.78E-33 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS03285 38c27cc5968896a98591c699b3661612 716 Gene3D G3DSA:3.30.470.20 506 587 1.5E-5 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS03285 38c27cc5968896a98591c699b3661612 716 SUPERFAMILY SSF56059 501 714 1.62E-36 T 22-04-2016 HRM2_RS03285 38c27cc5968896a98591c699b3661612 716 SUPERFAMILY SSF52210 133 295 4.58E-44 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS03285 38c27cc5968896a98591c699b3661612 716 Gene3D G3DSA:3.40.50.261 133 293 6.5E-34 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS17765 8f12c5d16b65dddb49a4345b4c5b0166 324 Hamap MF_01225_B Cyclic pyranopterin monophosphate synthase [moaA]. 1 324 35.674 T 22-04-2016 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 HRM2_RS17765 8f12c5d16b65dddb49a4345b4c5b0166 324 Pfam PF06463 Molybdenum Cofactor Synthesis C 180 306 6.7E-33 T 22-04-2016 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 HRM2_RS17765 8f12c5d16b65dddb49a4345b4c5b0166 324 PANTHER PTHR22960 8 272 5.1E-113 T 22-04-2016 HRM2_RS17765 8f12c5d16b65dddb49a4345b4c5b0166 324 PANTHER PTHR22960 288 297 5.1E-113 T 22-04-2016 HRM2_RS17765 8f12c5d16b65dddb49a4345b4c5b0166 324 Pfam PF04055 Radical SAM superfamily 12 171 6.7E-26 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS17765 8f12c5d16b65dddb49a4345b4c5b0166 324 Pfam PF13353 4Fe-4S single cluster domain 15 118 1.4E-6 T 22-04-2016 HRM2_RS17765 8f12c5d16b65dddb49a4345b4c5b0166 324 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 3 324 1.0E-109 T 22-04-2016 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 HRM2_RS17765 8f12c5d16b65dddb49a4345b4c5b0166 324 SMART SM00729 8 211 4.0E-6 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS17765 8f12c5d16b65dddb49a4345b4c5b0166 324 SUPERFAMILY SSF102114 3 275 2.49E-70 T 22-04-2016 HRM2_RS17765 8f12c5d16b65dddb49a4345b4c5b0166 324 Gene3D G3DSA:3.20.20.70 3 301 1.6E-73 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS16355 1e42b834534ac4b1b1fb33c65484a16b 401 Gene3D G3DSA:3.20.20.140 87 386 1.1E-55 T 22-04-2016 HRM2_RS16355 1e42b834534ac4b1b1fb33c65484a16b 401 SUPERFAMILY SSF51556 72 366 1.01E-62 T 22-04-2016 IPR032466 Metal-dependent hydrolase HRM2_RS16355 1e42b834534ac4b1b1fb33c65484a16b 401 Pfam PF01979 Amidohydrolase family 69 383 1.2E-34 T 22-04-2016 IPR006680 Amidohydrolase-related GO:0016787 HRM2_RS16355 1e42b834534ac4b1b1fb33c65484a16b 401 Gene3D G3DSA:2.30.40.10 31 86 3.2E-10 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS16355 1e42b834534ac4b1b1fb33c65484a16b 401 PANTHER PTHR11271 35 225 5.9E-55 T 22-04-2016 HRM2_RS16355 1e42b834534ac4b1b1fb33c65484a16b 401 PANTHER PTHR11271 243 383 5.9E-55 T 22-04-2016 HRM2_RS16355 1e42b834534ac4b1b1fb33c65484a16b 401 SUPERFAMILY SSF51338 32 85 3.12E-12 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS16355 1e42b834534ac4b1b1fb33c65484a16b 401 PANTHER PTHR11271:SF7 35 225 5.9E-55 T 22-04-2016 HRM2_RS16355 1e42b834534ac4b1b1fb33c65484a16b 401 PANTHER PTHR11271:SF7 243 383 5.9E-55 T 22-04-2016 HRM2_RS13740 5da7c55a91b46875e923431b3c115d6d 451 SUPERFAMILY SSF52172 1 175 3.42E-37 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS13740 5da7c55a91b46875e923431b3c115d6d 451 Pfam PF02954 Bacterial regulatory protein, Fis family 408 444 4.6E-9 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS13740 5da7c55a91b46875e923431b3c115d6d 451 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 411 428 4.3E-6 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS13740 5da7c55a91b46875e923431b3c115d6d 451 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 428 448 4.3E-6 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS13740 5da7c55a91b46875e923431b3c115d6d 451 Gene3D G3DSA:3.40.50.300 127 302 9.4E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13740 5da7c55a91b46875e923431b3c115d6d 451 SUPERFAMILY SSF46689 344 444 5.82E-8 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS13740 5da7c55a91b46875e923431b3c115d6d 451 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 216 231 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS13740 5da7c55a91b46875e923431b3c115d6d 451 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 154 167 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS13740 5da7c55a91b46875e923431b3c115d6d 451 PANTHER PTHR32071 1 444 4.1E-177 T 22-04-2016 HRM2_RS13740 5da7c55a91b46875e923431b3c115d6d 451 Pfam PF00158 Sigma-54 interaction domain 130 296 2.4E-68 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS13740 5da7c55a91b46875e923431b3c115d6d 451 SMART SM00382 150 298 5.1E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS13740 5da7c55a91b46875e923431b3c115d6d 451 SMART SM00448 1 101 2.1E-20 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS13740 5da7c55a91b46875e923431b3c115d6d 451 Pfam PF00072 Response regulator receiver domain 1 100 8.2E-23 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS13740 5da7c55a91b46875e923431b3c115d6d 451 Gene3D G3DSA:3.40.50.2300 1 113 9.9E-29 T 22-04-2016 HRM2_RS13740 5da7c55a91b46875e923431b3c115d6d 451 SUPERFAMILY SSF52540 130 371 1.44E-70 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13740 5da7c55a91b46875e923431b3c115d6d 451 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 343 352 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS13740 5da7c55a91b46875e923431b3c115d6d 451 Gene3D G3DSA:1.10.8.60 303 377 5.0E-20 T 22-04-2016 HRM2_RS13740 5da7c55a91b46875e923431b3c115d6d 451 Gene3D G3DSA:1.10.10.60 392 444 7.6E-8 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS23075 ad75c3a2d5a03f8545c2599d4b75b68e 336 Pfam PF13414 TPR repeat 263 300 2.9E-10 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS23075 ad75c3a2d5a03f8545c2599d4b75b68e 336 Pfam PF13414 TPR repeat 173 214 8.1E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS23075 ad75c3a2d5a03f8545c2599d4b75b68e 336 SUPERFAMILY SSF52172 1 123 1.85E-14 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS23075 ad75c3a2d5a03f8545c2599d4b75b68e 336 SMART SM00448 4 118 0.0041 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS23075 ad75c3a2d5a03f8545c2599d4b75b68e 336 PANTHER PTHR23083 250 325 1.7E-31 T 22-04-2016 HRM2_RS23075 ad75c3a2d5a03f8545c2599d4b75b68e 336 PANTHER PTHR23083 137 229 1.7E-31 T 22-04-2016 HRM2_RS23075 ad75c3a2d5a03f8545c2599d4b75b68e 336 SMART SM00028 166 199 2.8E-4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS23075 ad75c3a2d5a03f8545c2599d4b75b68e 336 SMART SM00028 200 233 6.5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS23075 ad75c3a2d5a03f8545c2599d4b75b68e 336 SMART SM00028 288 321 7.6E-4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS23075 ad75c3a2d5a03f8545c2599d4b75b68e 336 SMART SM00028 254 287 6.7E-5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS23075 ad75c3a2d5a03f8545c2599d4b75b68e 336 SUPERFAMILY SSF48452 134 324 7.78E-32 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS23075 ad75c3a2d5a03f8545c2599d4b75b68e 336 Gene3D G3DSA:3.40.50.2300 2 119 4.0E-13 T 22-04-2016 HRM2_RS23075 ad75c3a2d5a03f8545c2599d4b75b68e 336 Gene3D G3DSA:1.25.40.10 136 214 1.3E-18 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS23075 ad75c3a2d5a03f8545c2599d4b75b68e 336 Gene3D G3DSA:1.25.40.10 215 327 1.3E-20 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS23075 ad75c3a2d5a03f8545c2599d4b75b68e 336 Pfam PF00072 Response regulator receiver domain 6 112 7.7E-10 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS24005 a5b0fdf4dfae22e012e611d090275c6a 316 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 33 264 1.3E-16 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain HRM2_RS24005 a5b0fdf4dfae22e012e611d090275c6a 316 PANTHER PTHR30438:SF1 1 316 1.7E-76 T 22-04-2016 HRM2_RS24005 a5b0fdf4dfae22e012e611d090275c6a 316 Gene3D G3DSA:2.40.50.100 172 204 9.3E-10 T 22-04-2016 HRM2_RS24005 a5b0fdf4dfae22e012e611d090275c6a 316 Gene3D G3DSA:2.40.50.100 34 67 9.3E-10 T 22-04-2016 HRM2_RS24005 a5b0fdf4dfae22e012e611d090275c6a 316 PANTHER PTHR30438 1 316 1.7E-76 T 22-04-2016 HRM2_RS24005 a5b0fdf4dfae22e012e611d090275c6a 316 SUPERFAMILY SSF111369 28 250 3.27E-10 T 22-04-2016 HRM2_RS01845 9a17cf7925f19dd4d3747e7800043cf4 226 SMART SM00382 27 205 2.2E-16 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS01845 9a17cf7925f19dd4d3747e7800043cf4 226 Pfam PF00005 ABC transporter 21 157 1.4E-30 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS01845 9a17cf7925f19dd4d3747e7800043cf4 226 SUPERFAMILY SSF52540 2 218 1.71E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01845 9a17cf7925f19dd4d3747e7800043cf4 226 PANTHER PTHR24220 4 226 2.3E-78 T 22-04-2016 HRM2_RS01845 9a17cf7925f19dd4d3747e7800043cf4 226 Gene3D G3DSA:3.40.50.300 2 223 3.1E-63 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12960 f981fe793de164a0f6a8f66dd4e2c122 92 SUPERFAMILY SSF51161 3 77 1.8E-15 T 22-04-2016 IPR011004 Trimeric LpxA-like HRM2_RS12960 f981fe793de164a0f6a8f66dd4e2c122 92 Gene3D G3DSA:2.160.10.10 3 78 2.5E-15 T 22-04-2016 HRM2_RS12960 f981fe793de164a0f6a8f66dd4e2c122 92 PANTHER PTHR13061 3 76 2.5E-14 T 22-04-2016 HRM2_RS14255 1009b107d8d9bb06d34083e05fa2049b 429 SUPERFAMILY SSF53067 180 248 2.07E-32 T 22-04-2016 HRM2_RS14255 1009b107d8d9bb06d34083e05fa2049b 429 SUPERFAMILY SSF53067 304 425 2.07E-32 T 22-04-2016 HRM2_RS14255 1009b107d8d9bb06d34083e05fa2049b 429 PANTHER PTHR19375 3 241 9.7E-69 T 22-04-2016 HRM2_RS14255 1009b107d8d9bb06d34083e05fa2049b 429 PANTHER PTHR19375 298 422 9.7E-69 T 22-04-2016 HRM2_RS14255 1009b107d8d9bb06d34083e05fa2049b 429 Gene3D G3DSA:3.30.420.40 364 406 2.1E-15 T 22-04-2016 HRM2_RS14255 1009b107d8d9bb06d34083e05fa2049b 429 Gene3D G3DSA:3.30.420.40 187 220 2.1E-15 T 22-04-2016 HRM2_RS14255 1009b107d8d9bb06d34083e05fa2049b 429 PANTHER PTHR19375:SF182 3 241 9.7E-69 T 22-04-2016 HRM2_RS14255 1009b107d8d9bb06d34083e05fa2049b 429 PANTHER PTHR19375:SF182 298 422 9.7E-69 T 22-04-2016 HRM2_RS14255 1009b107d8d9bb06d34083e05fa2049b 429 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 382 396 - T 22-04-2016 IPR018181 Heat shock protein 70, conserved site HRM2_RS14255 1009b107d8d9bb06d34083e05fa2049b 429 SUPERFAMILY SSF53067 4 175 8.85E-25 T 22-04-2016 HRM2_RS14255 1009b107d8d9bb06d34083e05fa2049b 429 Gene3D G3DSA:3.30.420.40 105 186 1.7E-23 T 22-04-2016 HRM2_RS14255 1009b107d8d9bb06d34083e05fa2049b 429 Gene3D G3DSA:3.30.420.40 4 72 1.7E-23 T 22-04-2016 HRM2_RS14255 1009b107d8d9bb06d34083e05fa2049b 429 Pfam PF00012 Hsp70 protein 312 409 7.0E-12 T 22-04-2016 IPR013126 Heat shock protein 70 family HRM2_RS14255 1009b107d8d9bb06d34083e05fa2049b 429 Pfam PF00012 Hsp70 protein 91 231 2.2E-11 T 22-04-2016 IPR013126 Heat shock protein 70 family HRM2_RS13825 ee412cca63dcd2ffc15963922cdcb32b 251 PANTHER PTHR21139 1 251 4.9E-112 T 22-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 HRM2_RS13825 ee412cca63dcd2ffc15963922cdcb32b 251 SUPERFAMILY SSF51351 3 250 5.24E-91 T 22-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 HRM2_RS13825 ee412cca63dcd2ffc15963922cdcb32b 251 Pfam PF00121 Triosephosphate isomerase 6 248 3.5E-91 T 22-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 HRM2_RS13825 ee412cca63dcd2ffc15963922cdcb32b 251 ProSitePatterns PS00171 Triosephosphate isomerase active site. 166 176 - T 22-04-2016 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 HRM2_RS13825 ee412cca63dcd2ffc15963922cdcb32b 251 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 6 242 1.2E-59 T 22-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 HRM2_RS13825 ee412cca63dcd2ffc15963922cdcb32b 251 Gene3D G3DSA:3.20.20.70 3 249 3.3E-101 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS13825 ee412cca63dcd2ffc15963922cdcb32b 251 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 3 251 39.342 T 22-04-2016 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 HRM2_RS11470 55819ac1ee7366a2e8055f299ef8ad48 430 Gene3D G3DSA:3.40.50.720 3 222 2.6E-55 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS11470 55819ac1ee7366a2e8055f299ef8ad48 430 SUPERFAMILY SSF48179 201 292 1.62E-23 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HRM2_RS11470 55819ac1ee7366a2e8055f299ef8ad48 430 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 202 290 7.1E-23 T 22-04-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 HRM2_RS11470 55819ac1ee7366a2e8055f299ef8ad48 430 SMART SM00984 317 417 1.8E-23 T 22-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 HRM2_RS11470 55819ac1ee7366a2e8055f299ef8ad48 430 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 7 181 5.4E-31 T 22-04-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 HRM2_RS11470 55819ac1ee7366a2e8055f299ef8ad48 430 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 317 416 7.4E-19 T 22-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 HRM2_RS11470 55819ac1ee7366a2e8055f299ef8ad48 430 SUPERFAMILY SSF51735 7 192 5.0E-44 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS11470 55819ac1ee7366a2e8055f299ef8ad48 430 PANTHER PTHR11374 3 430 1.3E-214 T 22-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 HRM2_RS11470 55819ac1ee7366a2e8055f299ef8ad48 430 PIRSF PIRSF500136 1 430 2.2E-143 T 22-04-2016 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 HRM2_RS11470 55819ac1ee7366a2e8055f299ef8ad48 430 SUPERFAMILY SSF52413 302 427 1.83E-24 T 22-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 HRM2_RS11470 55819ac1ee7366a2e8055f299ef8ad48 430 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 7 400 7.4E-116 T 22-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 HRM2_RS11470 55819ac1ee7366a2e8055f299ef8ad48 430 Gene3D G3DSA:3.40.50.720 233 429 1.1E-39 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS11470 55819ac1ee7366a2e8055f299ef8ad48 430 PIRSF PIRSF000124 6 429 7.0E-59 T 22-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 HRM2_RS11470 55819ac1ee7366a2e8055f299ef8ad48 430 PANTHER PTHR11374:SF25 3 430 1.3E-214 T 22-04-2016 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 Gene3D G3DSA:1.25.40.10 30 289 2.7E-52 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 PANTHER PTHR23083 347 479 3.8E-76 T 22-04-2016 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 PANTHER PTHR23083 552 761 3.8E-76 T 22-04-2016 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 PANTHER PTHR23083 35 176 3.8E-76 T 22-04-2016 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 Gene3D G3DSA:1.25.40.10 290 342 2.7E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 Gene3D G3DSA:1.25.40.10 546 747 3.6E-39 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 Gene3D G3DSA:1.25.40.10 343 541 1.3E-31 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 Pfam PF13181 Tetratricopeptide repeat 545 575 0.0061 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 Pfam PF13181 Tetratricopeptide repeat 614 642 1.6E-5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 Pfam PF13181 Tetratricopeptide repeat 715 745 1.8E-5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 Pfam PF13181 Tetratricopeptide repeat 472 500 0.051 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 Pfam PF13432 Tetratricopeptide repeat 209 264 2.1E-5 T 22-04-2016 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 Pfam PF13432 Tetratricopeptide repeat 38 95 0.0053 T 22-04-2016 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 Pfam PF13432 Tetratricopeptide repeat 406 470 1.4E-4 T 22-04-2016 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 Pfam PF13432 Tetratricopeptide repeat 344 400 0.0031 T 22-04-2016 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 SUPERFAMILY SSF48452 331 466 2.15E-19 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 SUPERFAMILY SSF48452 422 744 4.68E-33 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 SMART SM00028 28 61 110.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 SMART SM00028 130 163 14.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 SMART SM00028 713 746 7.1E-5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 SMART SM00028 610 643 1.6E-4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 SMART SM00028 96 129 33.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 SMART SM00028 232 265 0.44 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 SMART SM00028 542 575 0.035 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 SMART SM00028 368 401 0.89 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 SMART SM00028 470 503 13.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 SMART SM00028 436 469 53.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 SMART SM00028 402 435 11.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 SMART SM00028 62 95 1.6E-4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 SMART SM00028 576 609 43.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 SMART SM00028 266 299 10.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 SMART SM00028 164 197 110.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 SMART SM00028 679 712 330.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 Pfam PF14559 Tetratricopeptide repeat 283 342 8.4E-8 T 22-04-2016 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 Pfam PF14559 Tetratricopeptide repeat 111 172 6.1E-7 T 22-04-2016 HRM2_RS10050 cf18da122c9ff470604d9828da4ea17b 761 SUPERFAMILY SSF48452 35 311 2.28E-36 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS15085 24ed63008d4ee473f89e8883e2103143 447 Gene3D G3DSA:2.130.10.10 171 442 8.4E-72 T 22-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 HRM2_RS15085 24ed63008d4ee473f89e8883e2103143 447 SUPERFAMILY SSF69304 175 441 1.96E-49 T 22-04-2016 HRM2_RS15085 24ed63008d4ee473f89e8883e2103143 447 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 28 441 8.4E-112 T 22-04-2016 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 HRM2_RS15085 24ed63008d4ee473f89e8883e2103143 447 SUPERFAMILY SSF52964 42 178 1.96E-23 T 22-04-2016 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 HRM2_RS15085 24ed63008d4ee473f89e8883e2103143 447 PANTHER PTHR36842 8 441 3.1E-31 T 22-04-2016 HRM2_RS15085 24ed63008d4ee473f89e8883e2103143 447 Hamap MF_00671 Protein TolB [tolB]. 14 440 29.603 T 22-04-2016 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 HRM2_RS15085 24ed63008d4ee473f89e8883e2103143 447 Pfam PF07676 WD40-like Beta Propeller Repeat 294 329 1.1E-10 T 22-04-2016 IPR011659 WD40-like Beta Propeller HRM2_RS15085 24ed63008d4ee473f89e8883e2103143 447 Pfam PF07676 WD40-like Beta Propeller Repeat 338 373 6.4E-9 T 22-04-2016 IPR011659 WD40-like Beta Propeller HRM2_RS15085 24ed63008d4ee473f89e8883e2103143 447 Pfam PF07676 WD40-like Beta Propeller Repeat 208 242 7.4E-10 T 22-04-2016 IPR011659 WD40-like Beta Propeller HRM2_RS15085 24ed63008d4ee473f89e8883e2103143 447 Pfam PF07676 WD40-like Beta Propeller Repeat 382 417 1.1E-7 T 22-04-2016 IPR011659 WD40-like Beta Propeller HRM2_RS15085 24ed63008d4ee473f89e8883e2103143 447 Gene3D G3DSA:3.40.50.10070 34 170 1.2E-22 T 22-04-2016 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 HRM2_RS15085 24ed63008d4ee473f89e8883e2103143 447 Pfam PF04052 TolB amino-terminal domain 36 144 1.8E-11 T 22-04-2016 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 HRM2_RS02735 3c6566115f24dc4942e9c1ce953759fa 202 PANTHER PTHR36531:SF1 12 201 2.2E-18 T 22-04-2016 HRM2_RS02735 3c6566115f24dc4942e9c1ce953759fa 202 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 14 202 6.0E-38 T 22-04-2016 IPR013343 CRISPR-associated protein Cas4 HRM2_RS02735 3c6566115f24dc4942e9c1ce953759fa 202 PANTHER PTHR36531 12 201 2.2E-18 T 22-04-2016 HRM2_RS02735 3c6566115f24dc4942e9c1ce953759fa 202 Pfam PF01930 Domain of unknown function DUF83 21 202 8.2E-16 T 22-04-2016 IPR022765 Dna2/Cas4, domain of unknown function DUF83 HRM2_RS07810 76290e31adb5caf54253914a868c46ac 629 Pfam PF00072 Response regulator receiver domain 58 153 1.6E-6 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS07810 76290e31adb5caf54253914a868c46ac 629 Pfam PF00563 EAL domain 362 597 5.0E-69 T 22-04-2016 IPR001633 EAL domain HRM2_RS07810 76290e31adb5caf54253914a868c46ac 629 Pfam PF00990 Diguanylate cyclase, GGDEF domain 176 341 9.4E-47 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS07810 76290e31adb5caf54253914a868c46ac 629 Gene3D G3DSA:3.30.70.270 178 353 5.7E-57 T 22-04-2016 HRM2_RS07810 76290e31adb5caf54253914a868c46ac 629 SUPERFAMILY SSF52172 11 183 2.94E-12 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS07810 76290e31adb5caf54253914a868c46ac 629 PANTHER PTHR10799:SF774 557 576 3.1E-84 T 22-04-2016 HRM2_RS07810 76290e31adb5caf54253914a868c46ac 629 PANTHER PTHR10799:SF774 209 436 3.1E-84 T 22-04-2016 HRM2_RS07810 76290e31adb5caf54253914a868c46ac 629 PANTHER PTHR10799:SF774 97 164 3.1E-84 T 22-04-2016 HRM2_RS07810 76290e31adb5caf54253914a868c46ac 629 SUPERFAMILY SSF141868 361 609 1.1E-87 T 22-04-2016 IPR001633 EAL domain HRM2_RS07810 76290e31adb5caf54253914a868c46ac 629 SMART SM00267 165 346 1.4E-61 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS07810 76290e31adb5caf54253914a868c46ac 629 SMART SM00052 356 602 8.8E-116 T 22-04-2016 IPR001633 EAL domain HRM2_RS07810 76290e31adb5caf54253914a868c46ac 629 Gene3D G3DSA:3.20.20.450 360 609 1.1E-96 T 22-04-2016 IPR001633 EAL domain HRM2_RS07810 76290e31adb5caf54253914a868c46ac 629 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 172 343 1.2E-40 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS07810 76290e31adb5caf54253914a868c46ac 629 PANTHER PTHR10799 557 576 3.1E-84 T 22-04-2016 HRM2_RS07810 76290e31adb5caf54253914a868c46ac 629 PANTHER PTHR10799 209 436 3.1E-84 T 22-04-2016 HRM2_RS07810 76290e31adb5caf54253914a868c46ac 629 PANTHER PTHR10799 97 164 3.1E-84 T 22-04-2016 HRM2_RS07810 76290e31adb5caf54253914a868c46ac 629 Gene3D G3DSA:3.40.50.2300 9 167 1.1E-28 T 22-04-2016 HRM2_RS07810 76290e31adb5caf54253914a868c46ac 629 SUPERFAMILY SSF55073 181 348 2.2E-47 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS13110 c6a26e397a15ab8aa61a21620864abcb 665 PANTHER PTHR10887 72 98 3.5E-76 T 22-04-2016 HRM2_RS13110 c6a26e397a15ab8aa61a21620864abcb 665 PANTHER PTHR10887 189 357 3.5E-76 T 22-04-2016 HRM2_RS13110 c6a26e397a15ab8aa61a21620864abcb 665 Hamap MF_01487 RecBCD enzyme subunit RecD [recD]. 34 664 50.461 T 22-04-2016 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 HRM2_RS13110 c6a26e397a15ab8aa61a21620864abcb 665 PANTHER PTHR10887:SF351 72 98 3.5E-76 T 22-04-2016 HRM2_RS13110 c6a26e397a15ab8aa61a21620864abcb 665 PANTHER PTHR10887:SF351 189 357 3.5E-76 T 22-04-2016 HRM2_RS13110 c6a26e397a15ab8aa61a21620864abcb 665 Gene3D G3DSA:3.40.50.300 584 643 4.9E-10 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13110 c6a26e397a15ab8aa61a21620864abcb 665 Pfam PF13604 AAA domain 198 359 1.4E-30 T 22-04-2016 HRM2_RS13110 c6a26e397a15ab8aa61a21620864abcb 665 Pfam PF13538 UvrD-like helicase C-terminal domain 592 639 4.2E-15 T 22-04-2016 IPR027785 UvrD-like helicase C-terminal domain HRM2_RS13110 c6a26e397a15ab8aa61a21620864abcb 665 SUPERFAMILY SSF52540 323 420 3.1E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13110 c6a26e397a15ab8aa61a21620864abcb 665 Gene3D G3DSA:3.40.50.300 146 360 7.1E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13110 c6a26e397a15ab8aa61a21620864abcb 665 Gene3D G3DSA:3.40.50.300 392 420 7.1E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13110 c6a26e397a15ab8aa61a21620864abcb 665 TIGRFAM TIGR01447 recD: exodeoxyribonuclease V, alpha subunit 27 662 1.9E-171 T 22-04-2016 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 HRM2_RS13110 c6a26e397a15ab8aa61a21620864abcb 665 SUPERFAMILY SSF52540 24 402 5.02E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13110 c6a26e397a15ab8aa61a21620864abcb 665 SUPERFAMILY SSF52540 495 663 3.1E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24095 0d071a92a20d3f9a4d5a94996afd88b2 382 SUPERFAMILY SSF56645 8 241 2.62E-72 T 22-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 HRM2_RS24095 0d071a92a20d3f9a4d5a94996afd88b2 382 SUPERFAMILY SSF47203 228 381 7.25E-60 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS24095 0d071a92a20d3f9a4d5a94996afd88b2 382 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 22-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 HRM2_RS24095 0d071a92a20d3f9a4d5a94996afd88b2 382 PANTHER PTHR10909 2 380 7.0E-161 T 22-04-2016 HRM2_RS24095 0d071a92a20d3f9a4d5a94996afd88b2 382 PIRSF PIRSF016578 4 382 1.3E-25 T 22-04-2016 HRM2_RS24095 0d071a92a20d3f9a4d5a94996afd88b2 382 PANTHER PTHR10909:SF305 2 380 7.0E-161 T 22-04-2016 HRM2_RS24095 0d071a92a20d3f9a4d5a94996afd88b2 382 Gene3D G3DSA:2.40.110.10 121 218 3.7E-30 T 22-04-2016 HRM2_RS24095 0d071a92a20d3f9a4d5a94996afd88b2 382 Gene3D G3DSA:1.10.540.10 6 119 1.1E-39 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS24095 0d071a92a20d3f9a4d5a94996afd88b2 382 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 22-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 HRM2_RS24095 0d071a92a20d3f9a4d5a94996afd88b2 382 Gene3D G3DSA:1.20.140.10 219 381 6.2E-71 T 22-04-2016 HRM2_RS24095 0d071a92a20d3f9a4d5a94996afd88b2 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 378 3.5E-53 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS24095 0d071a92a20d3f9a4d5a94996afd88b2 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 118 3.8E-35 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS24095 0d071a92a20d3f9a4d5a94996afd88b2 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 1.5E-21 T 22-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 HRM2_RS01305 67019c78c60292f7b77fb9cac9510ace 409 Pfam PF00155 Aminotransferase class I and II 35 402 3.0E-31 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HRM2_RS01305 67019c78c60292f7b77fb9cac9510ace 409 Gene3D G3DSA:3.90.1150.10 251 407 8.8E-33 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS01305 67019c78c60292f7b77fb9cac9510ace 409 PANTHER PTHR11751:SF22 16 407 3.0E-148 T 22-04-2016 IPR019942 LL-diaminopimelate aminotransferase GO:0009089|GO:0010285 KEGG: 00300+2.6.1.83|MetaCyc: PWY-5097|UniPathway: UPA00034 HRM2_RS01305 67019c78c60292f7b77fb9cac9510ace 409 Hamap MF_01642 LL-diaminopimelate aminotransferase [dapL]. 3 406 51.559 T 22-04-2016 IPR019942 LL-diaminopimelate aminotransferase GO:0009089|GO:0010285 KEGG: 00300+2.6.1.83|MetaCyc: PWY-5097|UniPathway: UPA00034 HRM2_RS01305 67019c78c60292f7b77fb9cac9510ace 409 PANTHER PTHR11751 16 407 3.0E-148 T 22-04-2016 HRM2_RS01305 67019c78c60292f7b77fb9cac9510ace 409 Gene3D G3DSA:3.40.640.10 49 250 9.1E-38 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS01305 67019c78c60292f7b77fb9cac9510ace 409 SUPERFAMILY SSF53383 14 408 7.26E-74 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS01305 67019c78c60292f7b77fb9cac9510ace 409 TIGRFAM TIGR03542 DAPAT_plant: LL-diaminopimelate aminotransferase 3 406 5.9E-172 T 22-04-2016 IPR019942 LL-diaminopimelate aminotransferase GO:0009089|GO:0010285 KEGG: 00300+2.6.1.83|MetaCyc: PWY-5097|UniPathway: UPA00034 HRM2_RS13910 08b666e3610187426160df06484e491a 227 Gene3D G3DSA:3.40.50.1580 36 214 3.8E-39 T 22-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HRM2_RS13910 08b666e3610187426160df06484e491a 227 SUPERFAMILY SSF53167 34 214 3.93E-42 T 22-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HRM2_RS13910 08b666e3610187426160df06484e491a 227 PANTHER PTHR21234 48 188 3.2E-20 T 22-04-2016 IPR018017 Nucleoside phosphorylase HRM2_RS13910 08b666e3610187426160df06484e491a 227 PANTHER PTHR21234:SF23 48 188 3.2E-20 T 22-04-2016 HRM2_RS13910 08b666e3610187426160df06484e491a 227 Pfam PF01048 Phosphorylase superfamily 39 213 8.2E-35 T 22-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HRM2_RS08350 75520d2c17145e209efd4e77ace13b7a 312 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 5 311 1.1E-122 T 22-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 HRM2_RS08350 75520d2c17145e209efd4e77ace13b7a 312 SMART SM01400 4 120 9.1E-77 T 22-04-2016 HRM2_RS08350 75520d2c17145e209efd4e77ace13b7a 312 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 5 120 1.4E-49 T 22-04-2016 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 HRM2_RS08350 75520d2c17145e209efd4e77ace13b7a 312 PANTHER PTHR10210 1 311 2.2E-177 T 22-04-2016 HRM2_RS08350 75520d2c17145e209efd4e77ace13b7a 312 Pfam PF14572 Phosphoribosyl synthetase-associated domain 197 311 4.4E-29 T 22-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 HRM2_RS08350 75520d2c17145e209efd4e77ace13b7a 312 SUPERFAMILY SSF53271 69 303 1.55E-63 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like HRM2_RS08350 75520d2c17145e209efd4e77ace13b7a 312 Gene3D G3DSA:3.40.50.2020 159 285 8.6E-55 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like HRM2_RS08350 75520d2c17145e209efd4e77ace13b7a 312 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 4 312 47.862 T 22-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 HRM2_RS08350 75520d2c17145e209efd4e77ace13b7a 312 Gene3D G3DSA:3.40.50.2020 1 158 2.1E-75 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like HRM2_RS08350 75520d2c17145e209efd4e77ace13b7a 312 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 128 143 - T 22-04-2016 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: REACT_474|UniPathway: UPA00087 HRM2_RS07820 2252b9f665a1a2c1864c611d970e959d 310 Gene3D G3DSA:3.30.565.10 156 304 2.8E-28 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS07820 2252b9f665a1a2c1864c611d970e959d 310 SUPERFAMILY SSF55874 150 304 3.26E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS07820 2252b9f665a1a2c1864c611d970e959d 310 SMART SM00387 194 306 1.5E-21 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS07820 2252b9f665a1a2c1864c611d970e959d 310 PRINTS PR00344 Bacterial sensor protein C-terminal signature 254 264 2.0E-10 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS07820 2252b9f665a1a2c1864c611d970e959d 310 PRINTS PR00344 Bacterial sensor protein C-terminal signature 236 250 2.0E-10 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS07820 2252b9f665a1a2c1864c611d970e959d 310 PRINTS PR00344 Bacterial sensor protein C-terminal signature 265 283 2.0E-10 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS07820 2252b9f665a1a2c1864c611d970e959d 310 PRINTS PR00344 Bacterial sensor protein C-terminal signature 290 303 2.0E-10 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS07820 2252b9f665a1a2c1864c611d970e959d 310 PANTHER PTHR24423 1 69 3.5E-30 T 22-04-2016 HRM2_RS07820 2252b9f665a1a2c1864c611d970e959d 310 PANTHER PTHR24423 115 303 3.5E-30 T 22-04-2016 HRM2_RS07820 2252b9f665a1a2c1864c611d970e959d 310 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 196 303 4.7E-12 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS07820 2252b9f665a1a2c1864c611d970e959d 310 PANTHER PTHR24423:SF562 1 69 3.5E-30 T 22-04-2016 HRM2_RS07820 2252b9f665a1a2c1864c611d970e959d 310 PANTHER PTHR24423:SF562 115 303 3.5E-30 T 22-04-2016 HRM2_RS18855 3f06a187fd1acf839cd2773b9ff47a7a 557 Gene3D G3DSA:1.10.287.130 323 386 6.4E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS18855 3f06a187fd1acf839cd2773b9ff47a7a 557 SMART SM00388 327 401 1.2E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS18855 3f06a187fd1acf839cd2773b9ff47a7a 557 PANTHER PTHR24423:SF360 38 60 3.7E-70 T 22-04-2016 HRM2_RS18855 3f06a187fd1acf839cd2773b9ff47a7a 557 PANTHER PTHR24423:SF360 311 555 3.7E-70 T 22-04-2016 HRM2_RS18855 3f06a187fd1acf839cd2773b9ff47a7a 557 SUPERFAMILY SSF47384 322 397 5.69E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS18855 3f06a187fd1acf839cd2773b9ff47a7a 557 Pfam PF00512 His Kinase A (phospho-acceptor) domain 327 398 2.6E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS18855 3f06a187fd1acf839cd2773b9ff47a7a 557 PRINTS PR00344 Bacterial sensor protein C-terminal signature 498 508 3.0E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS18855 3f06a187fd1acf839cd2773b9ff47a7a 557 PRINTS PR00344 Bacterial sensor protein C-terminal signature 480 494 3.0E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS18855 3f06a187fd1acf839cd2773b9ff47a7a 557 PRINTS PR00344 Bacterial sensor protein C-terminal signature 535 548 3.0E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS18855 3f06a187fd1acf839cd2773b9ff47a7a 557 PRINTS PR00344 Bacterial sensor protein C-terminal signature 511 529 3.0E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS18855 3f06a187fd1acf839cd2773b9ff47a7a 557 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 444 550 4.5E-26 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS18855 3f06a187fd1acf839cd2773b9ff47a7a 557 SMART SM00387 443 551 2.0E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS18855 3f06a187fd1acf839cd2773b9ff47a7a 557 Pfam PF02743 Cache domain 42 214 9.8E-15 T 22-04-2016 IPR033479 Double Cache domain 1 HRM2_RS18855 3f06a187fd1acf839cd2773b9ff47a7a 557 Gene3D G3DSA:3.30.565.10 387 551 5.9E-46 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS18855 3f06a187fd1acf839cd2773b9ff47a7a 557 PANTHER PTHR24423 38 60 3.7E-70 T 22-04-2016 HRM2_RS18855 3f06a187fd1acf839cd2773b9ff47a7a 557 PANTHER PTHR24423 311 555 3.7E-70 T 22-04-2016 HRM2_RS18855 3f06a187fd1acf839cd2773b9ff47a7a 557 SUPERFAMILY SSF55874 391 550 1.57E-45 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS13240 02ef6cf57af72aa2e8ae0225720338ca 759 PANTHER PTHR10314 1 338 3.7E-122 T 22-04-2016 HRM2_RS13240 02ef6cf57af72aa2e8ae0225720338ca 759 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 31 49 - T 22-04-2016 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 HRM2_RS13240 02ef6cf57af72aa2e8ae0225720338ca 759 SUPERFAMILY SSF52374 304 617 1.38E-46 T 22-04-2016 HRM2_RS13240 02ef6cf57af72aa2e8ae0225720338ca 759 TIGRFAM TIGR01136 cysKM: cysteine synthase 6 295 8.1E-106 T 22-04-2016 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936|UniPathway: UPA00136 HRM2_RS13240 02ef6cf57af72aa2e8ae0225720338ca 759 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 496 514 7.4E-14 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HRM2_RS13240 02ef6cf57af72aa2e8ae0225720338ca 759 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 362 371 7.4E-14 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HRM2_RS13240 02ef6cf57af72aa2e8ae0225720338ca 759 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 326 337 7.4E-14 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HRM2_RS13240 02ef6cf57af72aa2e8ae0225720338ca 759 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 527 548 7.4E-14 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HRM2_RS13240 02ef6cf57af72aa2e8ae0225720338ca 759 Gene3D G3DSA:3.40.50.1100 41 140 1.7E-34 T 22-04-2016 HRM2_RS13240 02ef6cf57af72aa2e8ae0225720338ca 759 SUPERFAMILY SSF53686 4 297 5.76E-89 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HRM2_RS13240 02ef6cf57af72aa2e8ae0225720338ca 759 Gene3D G3DSA:3.40.50.1100 149 296 7.7E-70 T 22-04-2016 HRM2_RS13240 02ef6cf57af72aa2e8ae0225720338ca 759 Gene3D G3DSA:3.40.50.1100 4 40 7.7E-70 T 22-04-2016 HRM2_RS13240 02ef6cf57af72aa2e8ae0225720338ca 759 Gene3D G3DSA:1.20.120.640 613 706 2.4E-12 T 22-04-2016 HRM2_RS13240 02ef6cf57af72aa2e8ae0225720338ca 759 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 303 759 25.71 T 22-04-2016 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16|Reactome: REACT_71 HRM2_RS13240 02ef6cf57af72aa2e8ae0225720338ca 759 SMART SM00840 653 717 3.9E-9 T 22-04-2016 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 HRM2_RS13240 02ef6cf57af72aa2e8ae0225720338ca 759 Pfam PF09190 DALR domain 654 713 3.5E-6 T 22-04-2016 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 HRM2_RS13240 02ef6cf57af72aa2e8ae0225720338ca 759 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 316 614 6.9E-64 T 22-04-2016 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 HRM2_RS13240 02ef6cf57af72aa2e8ae0225720338ca 759 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 33 46 - T 22-04-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 HRM2_RS13240 02ef6cf57af72aa2e8ae0225720338ca 759 SUPERFAMILY SSF47323 643 758 1.96E-19 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS13240 02ef6cf57af72aa2e8ae0225720338ca 759 Gene3D G3DSA:3.40.50.620 320 610 8.6E-53 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS13240 02ef6cf57af72aa2e8ae0225720338ca 759 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 6 284 1.9E-67 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HRM2_RS13240 02ef6cf57af72aa2e8ae0225720338ca 759 PANTHER PTHR10314:SF56 1 338 3.7E-122 T 22-04-2016 HRM2_RS19730 a4ad73d2b7c51dde1764cc3968f32fc7 112 Gene3D G3DSA:1.10.260.40 20 90 6.9E-13 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS19730 a4ad73d2b7c51dde1764cc3968f32fc7 112 SMART SM00530 23 78 1.0E-6 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS19730 a4ad73d2b7c51dde1764cc3968f32fc7 112 SUPERFAMILY SSF47413 7 77 2.55E-12 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS19730 a4ad73d2b7c51dde1764cc3968f32fc7 112 Pfam PF13560 Helix-turn-helix domain 20 73 4.7E-10 T 22-04-2016 HRM2_RS12385 0cb0aadefcac5e8370bd51da90dfa809 262 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 3 251 2.6E-66 T 22-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 HRM2_RS12385 0cb0aadefcac5e8370bd51da90dfa809 262 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 2 254 1.1E-45 T 22-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 HRM2_RS12385 0cb0aadefcac5e8370bd51da90dfa809 262 PANTHER PTHR30589:SF0 1 256 6.9E-76 T 22-04-2016 HRM2_RS12385 0cb0aadefcac5e8370bd51da90dfa809 262 PANTHER PTHR30589 1 256 6.9E-76 T 22-04-2016 HRM2_RS12385 0cb0aadefcac5e8370bd51da90dfa809 262 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 1 257 15.26 T 22-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 HRM2_RS04145 fe7f112692e6a207aaa2b40514153e52 290 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 37 266 7.6E-47 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS04145 fe7f112692e6a207aaa2b40514153e52 290 PANTHER PTHR30085:SF2 3 284 9.6E-60 T 22-04-2016 HRM2_RS04145 fe7f112692e6a207aaa2b40514153e52 290 Gene3D G3DSA:3.40.190.10 33 119 9.5E-26 T 22-04-2016 HRM2_RS04145 fe7f112692e6a207aaa2b40514153e52 290 Gene3D G3DSA:3.40.190.10 229 267 9.5E-26 T 22-04-2016 HRM2_RS04145 fe7f112692e6a207aaa2b40514153e52 290 SUPERFAMILY SSF53850 7 267 2.9E-57 T 22-04-2016 HRM2_RS04145 fe7f112692e6a207aaa2b40514153e52 290 Gene3D G3DSA:3.40.190.10 120 228 7.0E-19 T 22-04-2016 HRM2_RS04145 fe7f112692e6a207aaa2b40514153e52 290 SMART SM00062 35 268 2.0E-45 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS04145 fe7f112692e6a207aaa2b40514153e52 290 PANTHER PTHR30085 3 284 9.6E-60 T 22-04-2016 HRM2_RS15020 ca47f2325a1580141227de633642af81 89 Gene3D G3DSA:4.10.520.10 1 89 2.8E-33 T 22-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 HRM2_RS15020 ca47f2325a1580141227de633642af81 89 PANTHER PTHR33175 1 89 1.7E-36 T 22-04-2016 HRM2_RS15020 ca47f2325a1580141227de633642af81 89 SMART SM00411 1 89 1.3E-40 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 HRM2_RS15020 ca47f2325a1580141227de633642af81 89 SUPERFAMILY SSF47729 1 89 4.42E-29 T 22-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 HRM2_RS15020 ca47f2325a1580141227de633642af81 89 Pfam PF00216 Bacterial DNA-binding protein 1 89 1.2E-30 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 HRM2_RS15020 ca47f2325a1580141227de633642af81 89 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 45 64 - T 22-04-2016 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 HRM2_RS15020 ca47f2325a1580141227de633642af81 89 PRINTS PR01727 Prokaryotic integration host factor signature 73 87 1.4E-17 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 HRM2_RS15020 ca47f2325a1580141227de633642af81 89 PRINTS PR01727 Prokaryotic integration host factor signature 57 70 1.4E-17 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 HRM2_RS15020 ca47f2325a1580141227de633642af81 89 PRINTS PR01727 Prokaryotic integration host factor signature 39 54 1.4E-17 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 HRM2_RS01635 cc651b7fd23be128185a1693d95d92da 254 Pfam PF00005 ABC transporter 23 172 1.5E-32 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS01635 cc651b7fd23be128185a1693d95d92da 254 PANTHER PTHR24220:SF327 9 242 7.9E-113 T 22-04-2016 HRM2_RS01635 cc651b7fd23be128185a1693d95d92da 254 SMART SM00382 32 220 1.1E-15 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS01635 cc651b7fd23be128185a1693d95d92da 254 Gene3D G3DSA:3.40.50.300 6 238 4.7E-80 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01635 cc651b7fd23be128185a1693d95d92da 254 PIRSF PIRSF039085 4 248 2.1E-94 T 22-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 HRM2_RS01635 cc651b7fd23be128185a1693d95d92da 254 PANTHER PTHR24220 9 242 7.9E-113 T 22-04-2016 HRM2_RS01635 cc651b7fd23be128185a1693d95d92da 254 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS01635 cc651b7fd23be128185a1693d95d92da 254 SUPERFAMILY SSF52540 7 239 3.43E-74 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS15745 a433b5019e8554d81c65a4a19f21b607 567 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 276 2.1E-80 T 22-04-2016 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 UniPathway: UPA00056|UniPathway: UPA00059 HRM2_RS15745 a433b5019e8554d81c65a4a19f21b607 567 PANTHER PTHR30426 1 276 5.6E-93 T 22-04-2016 HRM2_RS15745 a433b5019e8554d81c65a4a19f21b607 567 Pfam PF02401 LytB protein 3 274 2.1E-85 T 22-04-2016 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 UniPathway: UPA00056|UniPathway: UPA00059 HRM2_RS15745 a433b5019e8554d81c65a4a19f21b607 567 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 278 30.615 T 22-04-2016 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 UniPathway: UPA00056|UniPathway: UPA00059 HRM2_RS15745 a433b5019e8554d81c65a4a19f21b607 567 Pfam PF01040 UbiA prenyltransferase family 323 536 5.6E-15 T 22-04-2016 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 HRM2_RS17915 905a09546e2c9f8ef33759a0669d65fc 155 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 13 155 4.2E-59 T 22-04-2016 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 HRM2_RS17915 905a09546e2c9f8ef33759a0669d65fc 155 PANTHER PTHR11205 24 155 4.1E-71 T 22-04-2016 IPR000235 Ribosomal protein S5/S7 GO:0006412 HRM2_RS17915 905a09546e2c9f8ef33759a0669d65fc 155 Pfam PF00177 Ribosomal protein S7p/S5e 2 148 2.3E-55 T 22-04-2016 IPR023798 Ribosomal protein S7 domain HRM2_RS17915 905a09546e2c9f8ef33759a0669d65fc 155 Gene3D G3DSA:1.10.455.10 18 155 7.8E-60 T 22-04-2016 IPR023798 Ribosomal protein S7 domain HRM2_RS17915 905a09546e2c9f8ef33759a0669d65fc 155 SUPERFAMILY SSF47973 23 155 2.62E-52 T 22-04-2016 IPR023798 Ribosomal protein S7 domain HRM2_RS17915 905a09546e2c9f8ef33759a0669d65fc 155 ProSitePatterns PS00052 Ribosomal protein S7 signature. 19 45 - T 22-04-2016 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 HRM2_RS17915 905a09546e2c9f8ef33759a0669d65fc 155 PIRSF PIRSF002122 7 155 1.1E-56 T 22-04-2016 IPR000235 Ribosomal protein S5/S7 GO:0006412 HRM2_RS17915 905a09546e2c9f8ef33759a0669d65fc 155 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 155 31.702 T 22-04-2016 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 HRM2_RS18305 6b0a7d97982c3b78b02ca2b51b87c2b0 270 PIRSF PIRSF003092 1 267 5.2E-81 T 22-04-2016 IPR025501 ATP binding protein MinD HRM2_RS18305 6b0a7d97982c3b78b02ca2b51b87c2b0 270 PANTHER PTHR13696 2 255 3.1E-83 T 22-04-2016 HRM2_RS18305 6b0a7d97982c3b78b02ca2b51b87c2b0 270 Gene3D G3DSA:3.40.50.300 1 245 1.7E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18305 6b0a7d97982c3b78b02ca2b51b87c2b0 270 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 212 4.1E-23 T 22-04-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain HRM2_RS18305 6b0a7d97982c3b78b02ca2b51b87c2b0 270 PANTHER PTHR13696:SF3 2 255 3.1E-83 T 22-04-2016 HRM2_RS18305 6b0a7d97982c3b78b02ca2b51b87c2b0 270 SUPERFAMILY SSF52540 1 245 7.41E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05190 b780b03780d33a3df5464995a6f124c7 179 PANTHER PTHR10516 132 141 2.4E-31 T 22-04-2016 IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type HRM2_RS05190 b780b03780d33a3df5464995a6f124c7 179 PANTHER PTHR10516 3 76 2.4E-31 T 22-04-2016 IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type HRM2_RS05190 b780b03780d33a3df5464995a6f124c7 179 SUPERFAMILY SSF54534 5 141 5.5E-43 T 22-04-2016 HRM2_RS05190 b780b03780d33a3df5464995a6f124c7 179 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 139 3.1E-29 T 22-04-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 HRM2_RS05190 b780b03780d33a3df5464995a6f124c7 179 Gene3D G3DSA:3.10.50.40 129 142 1.4E-34 T 22-04-2016 HRM2_RS05190 b780b03780d33a3df5464995a6f124c7 179 Gene3D G3DSA:3.10.50.40 3 80 1.4E-34 T 22-04-2016 HRM2_RS24320 e6b4c2df2d241c75c2d28cece7201aa0 391 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 318 324 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HRM2_RS24320 e6b4c2df2d241c75c2d28cece7201aa0 391 Pfam PF01170 Putative RNA methylase family UPF0020 178 357 9.5E-38 T 22-04-2016 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HRM2_RS24320 e6b4c2df2d241c75c2d28cece7201aa0 391 SUPERFAMILY SSF53335 270 365 4.25E-26 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS24320 e6b4c2df2d241c75c2d28cece7201aa0 391 SUPERFAMILY SSF53335 158 233 4.25E-26 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS24320 e6b4c2df2d241c75c2d28cece7201aa0 391 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 209 223 6.0E-5 T 22-04-2016 HRM2_RS24320 e6b4c2df2d241c75c2d28cece7201aa0 391 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 315 327 6.0E-5 T 22-04-2016 HRM2_RS24320 e6b4c2df2d241c75c2d28cece7201aa0 391 PANTHER PTHR14911 267 367 4.4E-36 T 22-04-2016 HRM2_RS24320 e6b4c2df2d241c75c2d28cece7201aa0 391 PANTHER PTHR14911 20 228 4.4E-36 T 22-04-2016 HRM2_RS24320 e6b4c2df2d241c75c2d28cece7201aa0 391 PANTHER PTHR14911:SF13 267 367 4.4E-36 T 22-04-2016 HRM2_RS24320 e6b4c2df2d241c75c2d28cece7201aa0 391 PANTHER PTHR14911:SF13 20 228 4.4E-36 T 22-04-2016 HRM2_RS24320 e6b4c2df2d241c75c2d28cece7201aa0 391 Gene3D G3DSA:3.40.50.150 166 230 1.3E-20 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS24320 e6b4c2df2d241c75c2d28cece7201aa0 391 Gene3D G3DSA:3.40.50.150 267 383 1.3E-20 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS18005 8c892386adcf5071c39553dcc1fece55 415 ProSitePatterns PS01276 Peptidase family U32 signature. 165 183 - T 22-04-2016 IPR001539 Peptidase U32 GO:0006508|GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- HRM2_RS18005 8c892386adcf5071c39553dcc1fece55 415 PANTHER PTHR30217:SF6 1 381 3.7E-178 T 22-04-2016 HRM2_RS18005 8c892386adcf5071c39553dcc1fece55 415 Pfam PF16325 Peptidase family U32 C-terminal domain 327 404 1.3E-11 T 22-04-2016 IPR032525 Peptidase family U32, C-terminal KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- HRM2_RS18005 8c892386adcf5071c39553dcc1fece55 415 Pfam PF01136 Peptidase family U32 84 311 2.5E-98 T 22-04-2016 IPR001539 Peptidase U32 GO:0006508|GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- HRM2_RS18005 8c892386adcf5071c39553dcc1fece55 415 PANTHER PTHR30217 1 381 3.7E-178 T 22-04-2016 HRM2_RS17545 ea492cfdca0706ce0f458529bd5f310d 526 Gene3D G3DSA:3.30.1330.90 317 446 3.9E-43 T 22-04-2016 IPR029009 Allosteric substrate binding domain HRM2_RS17545 ea492cfdca0706ce0f458529bd5f310d 526 SUPERFAMILY SSF52283 1 126 1.8E-37 T 22-04-2016 HRM2_RS17545 ea492cfdca0706ce0f458529bd5f310d 526 Gene3D G3DSA:3.30.70.260 447 516 1.8E-14 T 22-04-2016 HRM2_RS17545 ea492cfdca0706ce0f458529bd5f310d 526 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 106 280 1.5E-59 T 22-04-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 HRM2_RS17545 ea492cfdca0706ce0f458529bd5f310d 526 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 143 170 - T 22-04-2016 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 HRM2_RS17545 ea492cfdca0706ce0f458529bd5f310d 526 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 220 236 - T 22-04-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site HRM2_RS17545 ea492cfdca0706ce0f458529bd5f310d 526 PANTHER PTHR10996:SF20 1 356 3.7E-163 T 22-04-2016 HRM2_RS17545 ea492cfdca0706ce0f458529bd5f310d 526 Gene3D G3DSA:3.40.50.720 1 105 1.4E-39 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS17545 ea492cfdca0706ce0f458529bd5f310d 526 PANTHER PTHR10996 1 356 3.7E-163 T 22-04-2016 HRM2_RS17545 ea492cfdca0706ce0f458529bd5f310d 526 Gene3D G3DSA:3.40.50.720 106 282 9.2E-66 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS17545 ea492cfdca0706ce0f458529bd5f310d 526 SUPERFAMILY SSF55021 443 519 8.74E-14 T 22-04-2016 HRM2_RS17545 ea492cfdca0706ce0f458529bd5f310d 526 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 2 524 2.8E-189 T 22-04-2016 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|UniPathway: UPA00135 HRM2_RS17545 ea492cfdca0706ce0f458529bd5f310d 526 SUPERFAMILY SSF51735 100 281 2.01E-57 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS17545 ea492cfdca0706ce0f458529bd5f310d 526 SUPERFAMILY SSF143548 319 448 6.8E-37 T 22-04-2016 IPR029009 Allosteric substrate binding domain HRM2_RS17545 ea492cfdca0706ce0f458529bd5f310d 526 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3 312 1.0E-38 T 22-04-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 HRM2_RS25350 a4dd2ece3a9894dc30df18abc0f42adf 204 PANTHER PTHR30055 5 198 6.7E-23 T 22-04-2016 HRM2_RS25350 a4dd2ece3a9894dc30df18abc0f42adf 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 2.7E-8 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS25350 a4dd2ece3a9894dc30df18abc0f42adf 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 2.7E-8 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS25350 a4dd2ece3a9894dc30df18abc0f42adf 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 5.0E-16 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS25350 a4dd2ece3a9894dc30df18abc0f42adf 204 SUPERFAMILY SSF46689 11 82 7.28E-18 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS25350 a4dd2ece3a9894dc30df18abc0f42adf 204 Gene3D G3DSA:1.10.357.10 11 191 2.1E-30 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HRM2_RS13485 d53d028eb6dae170f88ef1c2c58eea1f 525 PANTHER PTHR30081 241 523 5.3E-144 T 22-04-2016 HRM2_RS13485 d53d028eb6dae170f88ef1c2c58eea1f 525 PANTHER PTHR30081 143 201 5.3E-144 T 22-04-2016 HRM2_RS13485 d53d028eb6dae170f88ef1c2c58eea1f 525 PANTHER PTHR30081 36 88 5.3E-144 T 22-04-2016 HRM2_RS13485 d53d028eb6dae170f88ef1c2c58eea1f 525 PANTHER PTHR30081:SF1 143 201 5.3E-144 T 22-04-2016 HRM2_RS13485 d53d028eb6dae170f88ef1c2c58eea1f 525 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 38 508 6.1E-145 T 22-04-2016 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 HRM2_RS13485 d53d028eb6dae170f88ef1c2c58eea1f 525 Pfam PF07549 SecD/SecF GG Motif 31 53 5.8E-6 T 22-04-2016 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site HRM2_RS13485 d53d028eb6dae170f88ef1c2c58eea1f 525 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 1 524 43.38 T 22-04-2016 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 HRM2_RS13485 d53d028eb6dae170f88ef1c2c58eea1f 525 PANTHER PTHR30081:SF1 241 523 5.3E-144 T 22-04-2016 HRM2_RS13485 d53d028eb6dae170f88ef1c2c58eea1f 525 PANTHER PTHR30081:SF1 36 88 5.3E-144 T 22-04-2016 HRM2_RS13485 d53d028eb6dae170f88ef1c2c58eea1f 525 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 274 504 1.1E-80 T 22-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial HRM2_RS13485 d53d028eb6dae170f88ef1c2c58eea1f 525 SUPERFAMILY SSF82866 321 514 1.1E-42 T 22-04-2016 HRM2_RS13485 d53d028eb6dae170f88ef1c2c58eea1f 525 Pfam PF02355 Protein export membrane protein 345 510 2.4E-18 T 22-04-2016 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial HRM2_RS13485 d53d028eb6dae170f88ef1c2c58eea1f 525 PRINTS PR00702 Acriflavin resistance protein family signature 413 437 3.6E-8 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS13485 d53d028eb6dae170f88ef1c2c58eea1f 525 PRINTS PR00702 Acriflavin resistance protein family signature 488 511 3.6E-8 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS13485 d53d028eb6dae170f88ef1c2c58eea1f 525 PRINTS PR00702 Acriflavin resistance protein family signature 360 383 3.6E-8 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS13485 d53d028eb6dae170f88ef1c2c58eea1f 525 Gene3D G3DSA:1.20.1640.10 320 517 9.6E-26 T 22-04-2016 HRM2_RS21060 dd26439375cca129053ca398ac83bbcb 77 SMART SM00899 4 76 2.3E-19 T 22-04-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 HRM2_RS21060 dd26439375cca129053ca398ac83bbcb 77 PANTHER PTHR33238:SF1 2 77 3.3E-12 T 22-04-2016 HRM2_RS21060 dd26439375cca129053ca398ac83bbcb 77 Gene3D G3DSA:1.10.599.10 5 73 9.1E-4 T 22-04-2016 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 HRM2_RS21060 dd26439375cca129053ca398ac83bbcb 77 Pfam PF04023 FeoA domain 4 75 1.2E-16 T 22-04-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 HRM2_RS21060 dd26439375cca129053ca398ac83bbcb 77 PANTHER PTHR33238 2 77 3.3E-12 T 22-04-2016 HRM2_RS21060 dd26439375cca129053ca398ac83bbcb 77 SUPERFAMILY SSF50037 8 76 1.03E-17 T 22-04-2016 IPR008988 Transcriptional repressor, C-terminal HRM2_RS12775 3a4cee7364852f456a24c7e1f4d2543a 622 Pfam PF02780 Transketolase, C-terminal domain 492 614 3.2E-34 T 22-04-2016 IPR033248 Transketolase, C-terminal domain HRM2_RS12775 3a4cee7364852f456a24c7e1f4d2543a 622 Gene3D G3DSA:3.40.50.970 3 188 1.1E-52 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS12775 3a4cee7364852f456a24c7e1f4d2543a 622 Gene3D G3DSA:3.40.50.970 236 294 1.1E-52 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS12775 3a4cee7364852f456a24c7e1f4d2543a 622 Gene3D G3DSA:3.40.50.920 493 621 1.2E-42 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HRM2_RS12775 3a4cee7364852f456a24c7e1f4d2543a 622 ProSitePatterns PS00801 Transketolase signature 1. 29 48 - T 22-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 HRM2_RS12775 3a4cee7364852f456a24c7e1f4d2543a 622 SMART SM00861 316 480 8.6E-72 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain HRM2_RS12775 3a4cee7364852f456a24c7e1f4d2543a 622 Pfam PF02779 Transketolase, pyrimidine binding domain 317 476 6.5E-43 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain HRM2_RS12775 3a4cee7364852f456a24c7e1f4d2543a 622 PANTHER PTHR11624 17 211 5.0E-289 T 22-04-2016 IPR033247 Transketolase family HRM2_RS12775 3a4cee7364852f456a24c7e1f4d2543a 622 PANTHER PTHR11624 238 621 5.0E-289 T 22-04-2016 IPR033247 Transketolase family HRM2_RS12775 3a4cee7364852f456a24c7e1f4d2543a 622 PANTHER PTHR11624:SF20 17 211 5.0E-289 T 22-04-2016 HRM2_RS12775 3a4cee7364852f456a24c7e1f4d2543a 622 PANTHER PTHR11624:SF20 238 621 5.0E-289 T 22-04-2016 HRM2_RS12775 3a4cee7364852f456a24c7e1f4d2543a 622 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 3 622 44.444 T 22-04-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 HRM2_RS12775 3a4cee7364852f456a24c7e1f4d2543a 622 SUPERFAMILY SSF52922 489 621 7.98E-35 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HRM2_RS12775 3a4cee7364852f456a24c7e1f4d2543a 622 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 6 614 4.6E-257 T 22-04-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 HRM2_RS12775 3a4cee7364852f456a24c7e1f4d2543a 622 ProSitePatterns PS00802 Transketolase signature 2. 422 438 - T 22-04-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 HRM2_RS12775 3a4cee7364852f456a24c7e1f4d2543a 622 SUPERFAMILY SSF52518 314 502 2.58E-60 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS12775 3a4cee7364852f456a24c7e1f4d2543a 622 SUPERFAMILY SSF52518 2 192 1.25E-74 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS12775 3a4cee7364852f456a24c7e1f4d2543a 622 SUPERFAMILY SSF52518 240 378 1.25E-74 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS12775 3a4cee7364852f456a24c7e1f4d2543a 622 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 4 279 2.8E-115 T 22-04-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 HRM2_RS12775 3a4cee7364852f456a24c7e1f4d2543a 622 Gene3D G3DSA:3.40.50.970 295 492 2.2E-74 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS20180 7f53228f7ecb80caea131277a087c0d9 266 PANTHER PTHR11918 13 188 1.2E-25 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein HRM2_RS20180 7f53228f7ecb80caea131277a087c0d9 266 PANTHER PTHR11918:SF47 13 188 1.2E-25 T 22-04-2016 HRM2_RS20180 7f53228f7ecb80caea131277a087c0d9 266 Gene3D G3DSA:3.80.30.20 8 212 1.2E-18 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe HRM2_RS20180 7f53228f7ecb80caea131277a087c0d9 266 Pfam PF04055 Radical SAM superfamily 12 146 4.9E-8 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS20180 7f53228f7ecb80caea131277a087c0d9 266 SMART SM00729 5 208 2.6E-4 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS20180 7f53228f7ecb80caea131277a087c0d9 266 SUPERFAMILY SSF102114 8 166 1.11E-19 T 22-04-2016 HRM2_RS23625 34835dcb54308e4823dc34619618c12b 379 SUPERFAMILY SSF52021 1 145 7.45E-55 T 22-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HRM2_RS23625 34835dcb54308e4823dc34619618c12b 379 SMART SM01097 1 131 5.0E-88 T 22-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HRM2_RS23625 34835dcb54308e4823dc34619618c12b 379 SUPERFAMILY SSF52317 183 377 8.07E-55 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS23625 34835dcb54308e4823dc34619618c12b 379 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 2 130 8.9E-52 T 22-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HRM2_RS23625 34835dcb54308e4823dc34619618c12b 379 Gene3D G3DSA:3.50.30.20 1 139 3.0E-58 T 22-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HRM2_RS23625 34835dcb54308e4823dc34619618c12b 379 PRINTS PR00097 Anthranilate synthase component II signature 237 246 9.0E-6 T 22-04-2016 HRM2_RS23625 34835dcb54308e4823dc34619618c12b 379 PRINTS PR00097 Anthranilate synthase component II signature 264 275 9.0E-6 T 22-04-2016 HRM2_RS23625 34835dcb54308e4823dc34619618c12b 379 PRINTS PR00097 Anthranilate synthase component II signature 350 363 9.0E-6 T 22-04-2016 HRM2_RS23625 34835dcb54308e4823dc34619618c12b 379 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 3 376 6.3E-146 T 22-04-2016 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HRM2_RS23625 34835dcb54308e4823dc34619618c12b 379 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 379 47.188 T 22-04-2016 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HRM2_RS23625 34835dcb54308e4823dc34619618c12b 379 PRINTS PR00096 Glutamine amidotransferase superfamily signature 237 246 2.1E-11 T 22-04-2016 HRM2_RS23625 34835dcb54308e4823dc34619618c12b 379 PRINTS PR00096 Glutamine amidotransferase superfamily signature 350 363 2.1E-11 T 22-04-2016 HRM2_RS23625 34835dcb54308e4823dc34619618c12b 379 PRINTS PR00096 Glutamine amidotransferase superfamily signature 264 275 2.1E-11 T 22-04-2016 HRM2_RS23625 34835dcb54308e4823dc34619618c12b 379 PANTHER PTHR11405 1 167 1.1E-204 T 22-04-2016 HRM2_RS23625 34835dcb54308e4823dc34619618c12b 379 PANTHER PTHR11405 189 377 1.1E-204 T 22-04-2016 HRM2_RS23625 34835dcb54308e4823dc34619618c12b 379 Gene3D G3DSA:3.40.50.880 150 377 1.7E-68 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS23625 34835dcb54308e4823dc34619618c12b 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 195 209 1.6E-38 T 22-04-2016 HRM2_RS23625 34835dcb54308e4823dc34619618c12b 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 234 248 1.6E-38 T 22-04-2016 HRM2_RS23625 34835dcb54308e4823dc34619618c12b 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 264 280 1.6E-38 T 22-04-2016 HRM2_RS23625 34835dcb54308e4823dc34619618c12b 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 281 298 1.6E-38 T 22-04-2016 HRM2_RS23625 34835dcb54308e4823dc34619618c12b 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 306 317 1.6E-38 T 22-04-2016 HRM2_RS23625 34835dcb54308e4823dc34619618c12b 379 Pfam PF00117 Glutamine amidotransferase class-I 197 372 3.4E-43 T 22-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 HRM2_RS16990 8e3a52c3558837ba5017dc35e8ba61d7 736 Gene3D G3DSA:1.10.287.560 357 412 1.7E-13 T 22-04-2016 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 HRM2_RS16990 8e3a52c3558837ba5017dc35e8ba61d7 736 SUPERFAMILY SSF50341 597 730 3.14E-24 T 22-04-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HRM2_RS16990 8e3a52c3558837ba5017dc35e8ba61d7 736 SUPERFAMILY SSF47226 154 260 4.32E-27 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HRM2_RS16990 8e3a52c3558837ba5017dc35e8ba61d7 736 Gene3D G3DSA:3.30.565.10 413 597 2.3E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS16990 8e3a52c3558837ba5017dc35e8ba61d7 736 Gene3D G3DSA:2.30.30.40 598 619 7.7E-19 T 22-04-2016 HRM2_RS16990 8e3a52c3558837ba5017dc35e8ba61d7 736 Gene3D G3DSA:2.30.30.40 685 729 7.7E-19 T 22-04-2016 HRM2_RS16990 8e3a52c3558837ba5017dc35e8ba61d7 736 SUPERFAMILY SSF55874 414 596 4.32E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS16990 8e3a52c3558837ba5017dc35e8ba61d7 736 Pfam PF01627 Hpt domain 157 249 2.2E-12 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HRM2_RS16990 8e3a52c3558837ba5017dc35e8ba61d7 736 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 357 412 2.8E-8 T 22-04-2016 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 HRM2_RS16990 8e3a52c3558837ba5017dc35e8ba61d7 736 SMART SM00260 590 730 4.8E-23 T 22-04-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HRM2_RS16990 8e3a52c3558837ba5017dc35e8ba61d7 736 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 462 597 1.7E-15 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS16990 8e3a52c3558837ba5017dc35e8ba61d7 736 SUPERFAMILY SSF47384 356 413 3.92E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS16990 8e3a52c3558837ba5017dc35e8ba61d7 736 SMART SM01231 354 412 1.1E-12 T 22-04-2016 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 HRM2_RS16990 8e3a52c3558837ba5017dc35e8ba61d7 736 PANTHER PTHR22617 135 729 3.6E-150 T 22-04-2016 HRM2_RS16990 8e3a52c3558837ba5017dc35e8ba61d7 736 Pfam PF01584 CheW-like domain 603 731 5.2E-16 T 22-04-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HRM2_RS16990 8e3a52c3558837ba5017dc35e8ba61d7 736 Gene3D G3DSA:1.20.120.160 153 283 8.4E-35 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HRM2_RS16990 8e3a52c3558837ba5017dc35e8ba61d7 736 SUPERFAMILY SSF160246 291 347 3.66E-6 T 22-04-2016 HRM2_RS16990 8e3a52c3558837ba5017dc35e8ba61d7 736 SMART SM00073 155 252 3.2E-23 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HRM2_RS16990 8e3a52c3558837ba5017dc35e8ba61d7 736 PANTHER PTHR22617:SF6 135 729 3.6E-150 T 22-04-2016 HRM2_RS16990 8e3a52c3558837ba5017dc35e8ba61d7 736 PRINTS PR00344 Bacterial sensor protein C-terminal signature 558 576 4.2E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS16990 8e3a52c3558837ba5017dc35e8ba61d7 736 PRINTS PR00344 Bacterial sensor protein C-terminal signature 502 516 4.2E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS16990 8e3a52c3558837ba5017dc35e8ba61d7 736 PRINTS PR00344 Bacterial sensor protein C-terminal signature 582 595 4.2E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS16990 8e3a52c3558837ba5017dc35e8ba61d7 736 SMART SM00387 457 598 5.2E-23 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS16990 8e3a52c3558837ba5017dc35e8ba61d7 736 Gene3D G3DSA:2.40.50.180 625 683 3.5E-6 T 22-04-2016 HRM2_RS11055 ad85b5dfdd53c7334595a3d304ca19ed 890 Pfam PF00571 CBS domain 319 366 0.0018 T 22-04-2016 IPR000644 CBS domain HRM2_RS11055 ad85b5dfdd53c7334595a3d304ca19ed 890 Pfam PF00571 CBS domain 383 437 8.2E-9 T 22-04-2016 IPR000644 CBS domain HRM2_RS11055 ad85b5dfdd53c7334595a3d304ca19ed 890 PANTHER PTHR13734:SF8 408 880 1.2E-121 T 22-04-2016 HRM2_RS11055 ad85b5dfdd53c7334595a3d304ca19ed 890 SUPERFAMILY SSF54631 317 439 6.44E-23 T 22-04-2016 HRM2_RS11055 ad85b5dfdd53c7334595a3d304ca19ed 890 Pfam PF01368 DHH family 10 154 4.5E-11 T 22-04-2016 IPR001667 DDH domain HRM2_RS11055 ad85b5dfdd53c7334595a3d304ca19ed 890 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 644 706 2.4E-5 T 22-04-2016 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain HRM2_RS11055 ad85b5dfdd53c7334595a3d304ca19ed 890 Gene3D G3DSA:3.90.1640.10 9 193 1.7E-28 T 22-04-2016 HRM2_RS11055 ad85b5dfdd53c7334595a3d304ca19ed 890 SMART SM00116 326 375 1.6 T 22-04-2016 IPR000644 CBS domain HRM2_RS11055 ad85b5dfdd53c7334595a3d304ca19ed 890 SMART SM00116 390 437 0.005 T 22-04-2016 IPR000644 CBS domain HRM2_RS11055 ad85b5dfdd53c7334595a3d304ca19ed 890 Gene3D G3DSA:3.10.580.10 319 438 8.5E-22 T 22-04-2016 HRM2_RS11055 ad85b5dfdd53c7334595a3d304ca19ed 890 SUPERFAMILY SSF81301 470 616 3.71E-31 T 22-04-2016 HRM2_RS11055 ad85b5dfdd53c7334595a3d304ca19ed 890 PANTHER PTHR13734 408 880 1.2E-121 T 22-04-2016 HRM2_RS11055 ad85b5dfdd53c7334595a3d304ca19ed 890 Pfam PF01743 Poly A polymerase head domain 492 619 1.6E-26 T 22-04-2016 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 HRM2_RS11055 ad85b5dfdd53c7334595a3d304ca19ed 890 Gene3D G3DSA:3.30.460.10 465 616 6.8E-37 T 22-04-2016 HRM2_RS11055 ad85b5dfdd53c7334595a3d304ca19ed 890 Pfam PF02272 DHHA1 domain 249 301 1.3E-6 T 22-04-2016 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7 HRM2_RS11055 ad85b5dfdd53c7334595a3d304ca19ed 890 SUPERFAMILY SSF81891 617 884 9.42E-35 T 22-04-2016 HRM2_RS11055 ad85b5dfdd53c7334595a3d304ca19ed 890 Gene3D G3DSA:1.10.3090.10 617 832 5.2E-34 T 22-04-2016 HRM2_RS11055 ad85b5dfdd53c7334595a3d304ca19ed 890 SUPERFAMILY SSF64182 10 306 2.62E-52 T 22-04-2016 HRM2_RS03195 6d1815f1061ceb54522e4b3880a307d6 1012 Pfam PF12770 CHAT domain 757 1010 3.0E-44 T 22-04-2016 IPR024983 CHAT domain HRM2_RS23125 7f3454b472261a0fd25613a012587c3c 372 PANTHER PTHR10632 5 318 3.6E-18 T 22-04-2016 HRM2_RS23125 7f3454b472261a0fd25613a012587c3c 372 SUPERFAMILY SSF51905 146 242 2.59E-9 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS23125 7f3454b472261a0fd25613a012587c3c 372 SUPERFAMILY SSF51905 237 313 2.71E-20 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS23125 7f3454b472261a0fd25613a012587c3c 372 SUPERFAMILY SSF51905 2 157 2.71E-20 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS23125 7f3454b472261a0fd25613a012587c3c 372 Gene3D G3DSA:3.50.50.60 108 309 1.5E-25 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS23125 7f3454b472261a0fd25613a012587c3c 372 Gene3D G3DSA:3.50.50.60 3 107 1.6E-15 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS23125 7f3454b472261a0fd25613a012587c3c 372 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 284 1.3E-26 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS05120 dac5e06d812c1de04b16589738b90b3a 274 Pfam PF07885 Ion channel 14 86 2.4E-17 T 22-04-2016 IPR013099 Potassium channel domain HRM2_RS05120 dac5e06d812c1de04b16589738b90b3a 274 SUPERFAMILY SSF81324 4 98 7.72E-25 T 22-04-2016 HRM2_RS05120 dac5e06d812c1de04b16589738b90b3a 274 Gene3D G3DSA:1.10.287.70 7 99 2.2E-21 T 22-04-2016 HRM2_RS22260 47d4736ab914d2df659da9377ba7d6f4 324 Pfam PF01738 Dienelactone hydrolase family 90 198 2.9E-8 T 22-04-2016 IPR002925 Dienelactone hydrolase GO:0016787 HRM2_RS22260 47d4736ab914d2df659da9377ba7d6f4 324 SUPERFAMILY SSF53474 61 316 7.96E-30 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS22260 47d4736ab914d2df659da9377ba7d6f4 324 Gene3D G3DSA:3.40.50.1820 57 314 1.1E-31 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS12535 3c7125f8743e7e52fbb413e2e7424990 103 Gene3D G3DSA:1.20.5.780 15 99 1.8E-25 T 22-04-2016 HRM2_RS12535 3c7125f8743e7e52fbb413e2e7424990 103 PANTHER PTHR35401 1 103 3.4E-25 T 22-04-2016 HRM2_RS12535 3c7125f8743e7e52fbb413e2e7424990 103 SUPERFAMILY SSF47598 16 93 1.63E-19 T 22-04-2016 IPR010985 Ribbon-helix-helix GO:0006355 HRM2_RS12535 3c7125f8743e7e52fbb413e2e7424990 103 Pfam PF08681 Protein of unknown function (DUF1778) 19 97 9.5E-23 T 22-04-2016 IPR014795 Vibrio phage ICP1, Orf50 HRM2_RS22565 542d125bf4db3c40ae99a8270bcfc368 442 PANTHER PTHR20852:SF7 1 442 4.1E-169 T 22-04-2016 HRM2_RS22565 542d125bf4db3c40ae99a8270bcfc368 442 SUPERFAMILY SSF55931 105 440 9.12E-126 T 22-04-2016 HRM2_RS22565 542d125bf4db3c40ae99a8270bcfc368 442 SUPERFAMILY SSF54368 2 102 9.68E-32 T 22-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HRM2_RS22565 542d125bf4db3c40ae99a8270bcfc368 442 Pfam PF00120 Glutamine synthetase, catalytic domain 104 438 2.6E-135 T 22-04-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HRM2_RS22565 542d125bf4db3c40ae99a8270bcfc368 442 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 14 96 3.8E-30 T 22-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HRM2_RS22565 542d125bf4db3c40ae99a8270bcfc368 442 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 231 246 - T 22-04-2016 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HRM2_RS22565 542d125bf4db3c40ae99a8270bcfc368 442 Gene3D G3DSA:3.10.20.70 2 106 1.1E-37 T 22-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HRM2_RS22565 542d125bf4db3c40ae99a8270bcfc368 442 SMART SM01230 103 352 6.3E-136 T 22-04-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HRM2_RS22565 542d125bf4db3c40ae99a8270bcfc368 442 Gene3D G3DSA:3.30.590.10 107 427 4.6E-125 T 22-04-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 HRM2_RS22565 542d125bf4db3c40ae99a8270bcfc368 442 PANTHER PTHR20852 1 442 4.1E-169 T 22-04-2016 HRM2_RS22565 542d125bf4db3c40ae99a8270bcfc368 442 ProSitePatterns PS00180 Glutamine synthetase signature 1. 49 67 - T 22-04-2016 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HRM2_RS22565 542d125bf4db3c40ae99a8270bcfc368 442 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 4 439 1.1E-166 T 22-04-2016 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HRM2_RS01665 61577ca51ec5d40eaa50c6966f9418c9 223 SUPERFAMILY SSF46894 121 219 3.97E-20 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HRM2_RS01665 61577ca51ec5d40eaa50c6966f9418c9 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 219 3.4E-17 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HRM2_RS01665 61577ca51ec5d40eaa50c6966f9418c9 223 PANTHER PTHR26402:SF552 1 221 2.8E-83 T 22-04-2016 HRM2_RS01665 61577ca51ec5d40eaa50c6966f9418c9 223 SMART SM00862 145 219 8.4E-16 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HRM2_RS01665 61577ca51ec5d40eaa50c6966f9418c9 223 SUPERFAMILY SSF52172 1 127 1.37E-38 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS01665 61577ca51ec5d40eaa50c6966f9418c9 223 SMART SM00448 1 113 5.0E-41 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS01665 61577ca51ec5d40eaa50c6966f9418c9 223 PANTHER PTHR26402 1 221 2.8E-83 T 22-04-2016 HRM2_RS01665 61577ca51ec5d40eaa50c6966f9418c9 223 Gene3D G3DSA:1.10.10.10 124 220 3.4E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS01665 61577ca51ec5d40eaa50c6966f9418c9 223 Gene3D G3DSA:3.40.50.2300 1 122 1.3E-38 T 22-04-2016 HRM2_RS01665 61577ca51ec5d40eaa50c6966f9418c9 223 Pfam PF00072 Response regulator receiver domain 3 114 7.9E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS15150 2f2ec4dfecec8c61b52bb97314f2b3e0 247 PANTHER PTHR12029 3 184 2.7E-34 T 22-04-2016 HRM2_RS15150 2f2ec4dfecec8c61b52bb97314f2b3e0 247 Gene3D G3DSA:3.40.1280.10 4 163 4.4E-31 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HRM2_RS15150 2f2ec4dfecec8c61b52bb97314f2b3e0 247 PIRSF PIRSF004808 2 243 1.5E-67 T 22-04-2016 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 HRM2_RS15150 2f2ec4dfecec8c61b52bb97314f2b3e0 247 SUPERFAMILY SSF75217 2 163 4.38E-36 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases HRM2_RS15150 2f2ec4dfecec8c61b52bb97314f2b3e0 247 Pfam PF00588 SpoU rRNA Methylase family 6 156 3.0E-35 T 22-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 HRM2_RS15150 2f2ec4dfecec8c61b52bb97314f2b3e0 247 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 4 237 8.0E-59 T 22-04-2016 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 HRM2_RS17790 23afa208e572b425250f3ef0fabb97ed 131 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 12 128 1.1E-56 T 22-04-2016 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17790 23afa208e572b425250f3ef0fabb97ed 131 Pfam PF00411 Ribosomal protein S11 21 130 2.4E-47 T 22-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17790 23afa208e572b425250f3ef0fabb97ed 131 Gene3D G3DSA:3.30.420.80 8 131 4.9E-55 T 22-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17790 23afa208e572b425250f3ef0fabb97ed 131 SUPERFAMILY SSF53137 16 131 8.29E-49 T 22-04-2016 HRM2_RS17790 23afa208e572b425250f3ef0fabb97ed 131 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 131 32.931 T 22-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17790 23afa208e572b425250f3ef0fabb97ed 131 ProSitePatterns PS00054 Ribosomal protein S11 signature. 99 121 - T 22-04-2016 IPR018102 Ribosomal S11, conserved site HRM2_RS17790 23afa208e572b425250f3ef0fabb97ed 131 PANTHER PTHR11759 13 131 4.2E-65 T 22-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17790 23afa208e572b425250f3ef0fabb97ed 131 PIRSF PIRSF002131 1 131 1.0E-52 T 22-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 HRM2_RS25330 0ac002f6d25676189a16259d9c5a3086 810 Gene3D G3DSA:3.30.450.20 396 551 6.3E-21 T 22-04-2016 HRM2_RS25330 0ac002f6d25676189a16259d9c5a3086 810 SMART SM00086 494 536 4.1E-6 T 22-04-2016 IPR001610 PAC motif HRM2_RS25330 0ac002f6d25676189a16259d9c5a3086 810 SMART SM00387 665 789 3.0E-27 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25330 0ac002f6d25676189a16259d9c5a3086 810 Pfam PF00512 His Kinase A (phospho-acceptor) domain 560 623 3.4E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25330 0ac002f6d25676189a16259d9c5a3086 810 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 410 542 6.8E-14 T 22-04-2016 IPR000014 PAS domain HRM2_RS25330 0ac002f6d25676189a16259d9c5a3086 810 SUPERFAMILY SSF55874 614 787 5.24E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25330 0ac002f6d25676189a16259d9c5a3086 810 SUPERFAMILY SSF47384 552 623 7.65E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25330 0ac002f6d25676189a16259d9c5a3086 810 Pfam PF07696 7TMR-DISM extracellular 2 46 177 3.2E-26 T 22-04-2016 IPR011622 7TM-DISM receptor, extracellular domain, type 2 HRM2_RS25330 0ac002f6d25676189a16259d9c5a3086 810 PANTHER PTHR24423 397 789 1.2E-103 T 22-04-2016 HRM2_RS25330 0ac002f6d25676189a16259d9c5a3086 810 Pfam PF07695 7TM diverse intracellular signalling 192 392 2.3E-36 T 22-04-2016 IPR011623 7TM-DISM receptor, extracellular domain, type 1 HRM2_RS25330 0ac002f6d25676189a16259d9c5a3086 810 Gene3D G3DSA:3.30.565.10 610 786 1.5E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25330 0ac002f6d25676189a16259d9c5a3086 810 SUPERFAMILY SSF55785 418 539 2.26E-18 T 22-04-2016 IPR000014 PAS domain HRM2_RS25330 0ac002f6d25676189a16259d9c5a3086 810 SMART SM00388 558 624 1.1E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25330 0ac002f6d25676189a16259d9c5a3086 810 PRINTS PR00344 Bacterial sensor protein C-terminal signature 749 767 2.4E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25330 0ac002f6d25676189a16259d9c5a3086 810 PRINTS PR00344 Bacterial sensor protein C-terminal signature 773 786 2.4E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25330 0ac002f6d25676189a16259d9c5a3086 810 PRINTS PR00344 Bacterial sensor protein C-terminal signature 736 746 2.4E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25330 0ac002f6d25676189a16259d9c5a3086 810 PRINTS PR00344 Bacterial sensor protein C-terminal signature 718 732 2.4E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25330 0ac002f6d25676189a16259d9c5a3086 810 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 666 788 4.4E-20 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25330 0ac002f6d25676189a16259d9c5a3086 810 PANTHER PTHR24423:SF544 397 789 1.2E-103 T 22-04-2016 HRM2_RS25330 0ac002f6d25676189a16259d9c5a3086 810 Gene3D G3DSA:1.10.287.130 553 609 1.2E-4 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25330 0ac002f6d25676189a16259d9c5a3086 810 Pfam PF13426 PAS domain 433 535 1.1E-10 T 22-04-2016 IPR000014 PAS domain HRM2_RS25330 0ac002f6d25676189a16259d9c5a3086 810 SMART SM00091 413 480 9.5E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS08750 41604c15cfc8c78e41aa62bdfd0818ef 342 SUPERFAMILY SSF81324 4 136 8.9E-29 T 22-04-2016 HRM2_RS08750 41604c15cfc8c78e41aa62bdfd0818ef 342 SUPERFAMILY SSF51735 115 263 1.57E-14 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS08750 41604c15cfc8c78e41aa62bdfd0818ef 342 Pfam PF02254 TrkA-N domain 119 241 8.5E-9 T 22-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 HRM2_RS08750 41604c15cfc8c78e41aa62bdfd0818ef 342 PANTHER PTHR16254 17 285 2.7E-29 T 22-04-2016 HRM2_RS08750 41604c15cfc8c78e41aa62bdfd0818ef 342 Gene3D G3DSA:1.10.287.70 18 63 5.6E-11 T 22-04-2016 HRM2_RS08750 41604c15cfc8c78e41aa62bdfd0818ef 342 Pfam PF06241 Castor and Pollux, part of voltage-gated ion channel 245 338 2.2E-9 T 22-04-2016 IPR010420 CASTOR/POLLUX/SYM8 ion channels HRM2_RS08750 41604c15cfc8c78e41aa62bdfd0818ef 342 Pfam PF07885 Ion channel 26 99 1.5E-17 T 22-04-2016 IPR013099 Potassium channel domain HRM2_RS08750 41604c15cfc8c78e41aa62bdfd0818ef 342 PRINTS PR00169 Potassium channel signature 44 66 1.8E-8 T 22-04-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 HRM2_RS08750 41604c15cfc8c78e41aa62bdfd0818ef 342 PRINTS PR00169 Potassium channel signature 73 99 1.8E-8 T 22-04-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 HRM2_RS08750 41604c15cfc8c78e41aa62bdfd0818ef 342 Gene3D G3DSA:3.40.50.720 110 240 5.6E-21 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS08750 41604c15cfc8c78e41aa62bdfd0818ef 342 Gene3D G3DSA:1.20.5.110 65 103 6.8E-16 T 22-04-2016 HRM2_RS08750 41604c15cfc8c78e41aa62bdfd0818ef 342 PANTHER PTHR16254:SF21 17 285 2.7E-29 T 22-04-2016 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 Pfam PF00639 PPIC-type PPIASE domain 587 667 1.4E-4 T 22-04-2016 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 SMART SM00663 236 515 6.5E-173 T 22-04-2016 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 PANTHER PTHR19376 1386 1445 0.0 T 22-04-2016 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 PANTHER PTHR19376 671 1029 0.0 T 22-04-2016 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 PANTHER PTHR19376 1260 1345 0.0 T 22-04-2016 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 Pfam PF05000 RNA polymerase Rpb1, domain 4 760 841 1.3E-17 T 22-04-2016 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 Gene3D G3DSA:2.40.50.100 1239 1293 2.5E-11 T 22-04-2016 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 Gene3D G3DSA:2.40.40.20 350 377 5.5E-35 T 22-04-2016 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 Gene3D G3DSA:2.40.40.20 418 490 5.5E-35 T 22-04-2016 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 SUPERFAMILY SSF64484 664 1030 0.0 T 22-04-2016 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 SUPERFAMILY SSF64484 1216 1449 0.0 T 22-04-2016 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 SUPERFAMILY SSF64484 15 609 0.0 T 22-04-2016 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 PANTHER PTHR19376:SF32 4 589 0.0 T 22-04-2016 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 PANTHER PTHR19376:SF32 1046 1240 0.0 T 22-04-2016 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 Pfam PF04998 RNA polymerase Rpb1, domain 5 852 1398 6.8E-68 T 22-04-2016 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 PANTHER PTHR19376:SF32 1260 1345 0.0 T 22-04-2016 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 PANTHER PTHR19376 4 589 0.0 T 22-04-2016 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 PANTHER PTHR19376 1046 1240 0.0 T 22-04-2016 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 Gene3D G3DSA:3.10.50.40 579 672 2.6E-9 T 22-04-2016 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 15 1459 10.241 T 22-04-2016 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 20 1450 0.0 T 22-04-2016 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 Gene3D G3DSA:2.40.50.100 1091 1137 4.6E-4 T 22-04-2016 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 PANTHER PTHR19376:SF32 1386 1445 0.0 T 22-04-2016 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 PANTHER PTHR19376:SF32 671 1029 0.0 T 22-04-2016 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 Pfam PF00623 RNA polymerase Rpb1, domain 2 345 486 4.0E-32 T 22-04-2016 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 Pfam PF04997 RNA polymerase Rpb1, domain 1 18 343 8.2E-84 T 22-04-2016 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 Pfam PF04983 RNA polymerase Rpb1, domain 3 490 574 4.3E-15 T 22-04-2016 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS17925 b26d8c24a025ef80f569e56a5375add2 1462 Pfam PF04983 RNA polymerase Rpb1, domain 3 682 731 3.5E-5 T 22-04-2016 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HRM2_RS05985 9e15f2d4a3830f887db0a3e367e9128e 464 Gene3D G3DSA:3.40.50.300 138 314 1.2E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05985 9e15f2d4a3830f887db0a3e367e9128e 464 Gene3D G3DSA:3.40.50.2300 4 134 2.2E-36 T 22-04-2016 HRM2_RS05985 9e15f2d4a3830f887db0a3e367e9128e 464 SUPERFAMILY SSF52540 142 383 4.48E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05985 9e15f2d4a3830f887db0a3e367e9128e 464 Gene3D G3DSA:1.10.8.60 315 386 2.6E-20 T 22-04-2016 HRM2_RS05985 9e15f2d4a3830f887db0a3e367e9128e 464 SUPERFAMILY SSF52172 4 186 1.29E-44 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS05985 9e15f2d4a3830f887db0a3e367e9128e 464 PANTHER PTHR32071 1 464 6.9E-180 T 22-04-2016 HRM2_RS05985 9e15f2d4a3830f887db0a3e367e9128e 464 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 355 364 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS05985 9e15f2d4a3830f887db0a3e367e9128e 464 Gene3D G3DSA:1.10.10.60 408 457 5.4E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS05985 9e15f2d4a3830f887db0a3e367e9128e 464 SMART SM00382 162 309 2.2E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS05985 9e15f2d4a3830f887db0a3e367e9128e 464 SMART SM00448 3 115 2.8E-31 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS05985 9e15f2d4a3830f887db0a3e367e9128e 464 Pfam PF00158 Sigma-54 interaction domain 142 309 1.7E-67 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS05985 9e15f2d4a3830f887db0a3e367e9128e 464 SUPERFAMILY SSF46689 355 458 1.16E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS05985 9e15f2d4a3830f887db0a3e367e9128e 464 Pfam PF00072 Response regulator receiver domain 5 115 1.3E-27 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS01055 dd2afd56b018d7f01261da60a1d6a088 187 SUPERFAMILY SSF81296 104 184 4.9E-17 T 22-04-2016 IPR014756 Immunoglobulin E-set HRM2_RS01055 dd2afd56b018d7f01261da60a1d6a088 187 Pfam PF16561 Glycogen recognition site of AMP-activated protein kinase 111 184 1.0E-8 T 22-04-2016 IPR032640 AMP-activated protein kinase, glycogen-binding domain HRM2_RS01055 dd2afd56b018d7f01261da60a1d6a088 187 Gene3D G3DSA:2.60.40.10 104 164 1.7E-8 T 22-04-2016 IPR013783 Immunoglobulin-like fold HRM2_RS03225 eb9b5e19d6883040342710df72cb0e6c 465 SUPERFAMILY SSF52540 81 178 1.01E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03225 eb9b5e19d6883040342710df72cb0e6c 465 SUPERFAMILY SSF52540 212 383 1.01E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03225 eb9b5e19d6883040342710df72cb0e6c 465 Pfam PF12631 MnmE helical domain 131 462 1.5E-51 T 22-04-2016 IPR025867 MnmE, helical domain HRM2_RS03225 eb9b5e19d6883040342710df72cb0e6c 465 Gene3D G3DSA:3.40.50.300 224 255 2.6E-5 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03225 eb9b5e19d6883040342710df72cb0e6c 465 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 4 465 32.291 T 22-04-2016 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 HRM2_RS03225 eb9b5e19d6883040342710df72cb0e6c 465 Pfam PF01926 50S ribosome-binding GTPase 227 338 9.0E-21 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS03225 eb9b5e19d6883040342710df72cb0e6c 465 Gene3D G3DSA:3.40.50.300 294 389 1.4E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03225 eb9b5e19d6883040342710df72cb0e6c 465 Pfam PF10396 GTP-binding protein TrmE N-terminus 5 128 2.1E-37 T 22-04-2016 IPR018948 GTP-binding protein TrmE, N-terminal HRM2_RS03225 eb9b5e19d6883040342710df72cb0e6c 465 PANTHER PTHR11649 7 465 1.4E-138 T 22-04-2016 HRM2_RS03225 eb9b5e19d6883040342710df72cb0e6c 465 Gene3D G3DSA:3.30.1360.120 2 129 5.0E-39 T 22-04-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 HRM2_RS03225 eb9b5e19d6883040342710df72cb0e6c 465 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 224 383 7.7E-27 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HRM2_RS03225 eb9b5e19d6883040342710df72cb0e6c 465 Gene3D G3DSA:1.20.120.430 395 465 3.2E-49 T 22-04-2016 IPR027368 tRNA modification GTPase MnmE domain 2 HRM2_RS03225 eb9b5e19d6883040342710df72cb0e6c 465 Gene3D G3DSA:1.20.120.430 256 279 3.2E-49 T 22-04-2016 IPR027368 tRNA modification GTPase MnmE domain 2 HRM2_RS03225 eb9b5e19d6883040342710df72cb0e6c 465 Gene3D G3DSA:1.20.120.430 130 190 3.2E-49 T 22-04-2016 IPR027368 tRNA modification GTPase MnmE domain 2 HRM2_RS03225 eb9b5e19d6883040342710df72cb0e6c 465 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 10 465 1.2E-110 T 22-04-2016 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 HRM2_RS03225 eb9b5e19d6883040342710df72cb0e6c 465 PANTHER PTHR11649:SF56 7 465 1.4E-138 T 22-04-2016 HRM2_RS11545 168e360e23ac8f5f1420093101171514 388 PANTHER PTHR11964 8 381 5.2E-252 T 22-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 HRM2_RS11545 168e360e23ac8f5f1420093101171514 388 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 119 129 - T 22-04-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 HRM2_RS11545 168e360e23ac8f5f1420093101171514 388 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 8 384 4.5E-182 T 22-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 HRM2_RS11545 168e360e23ac8f5f1420093101171514 388 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 7 104 1.0E-42 T 22-04-2016 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 HRM2_RS11545 168e360e23ac8f5f1420093101171514 388 SUPERFAMILY SSF55973 7 113 2.79E-46 T 22-04-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 HRM2_RS11545 168e360e23ac8f5f1420093101171514 388 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 5 386 56.231 T 22-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 HRM2_RS11545 168e360e23ac8f5f1420093101171514 388 SUPERFAMILY SSF55973 115 235 1.33E-50 T 22-04-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 HRM2_RS11545 168e360e23ac8f5f1420093101171514 388 PIRSF PIRSF000497 1 387 2.9E-172 T 22-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 HRM2_RS11545 168e360e23ac8f5f1420093101171514 388 Gene3D G3DSA:3.30.300.10 139 236 5.1E-45 T 22-04-2016 HRM2_RS11545 168e360e23ac8f5f1420093101171514 388 SUPERFAMILY SSF55973 236 386 1.29E-66 T 22-04-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 HRM2_RS11545 168e360e23ac8f5f1420093101171514 388 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 236 375 5.7E-66 T 22-04-2016 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 HRM2_RS11545 168e360e23ac8f5f1420093101171514 388 Gene3D G3DSA:3.30.300.10 247 386 3.9E-66 T 22-04-2016 HRM2_RS11545 168e360e23ac8f5f1420093101171514 388 Gene3D G3DSA:3.30.300.10 14 138 1.2E-47 T 22-04-2016 HRM2_RS11545 168e360e23ac8f5f1420093101171514 388 Pfam PF02772 S-adenosylmethionine synthetase, central domain 117 234 3.6E-47 T 22-04-2016 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 HRM2_RS11545 168e360e23ac8f5f1420093101171514 388 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 262 270 - T 22-04-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 HRM2_RS00590 8b841287328c1df963c5c6a894ea6a29 527 PANTHER PTHR30047:SF2 6 527 1.5E-166 T 22-04-2016 HRM2_RS00590 8b841287328c1df963c5c6a894ea6a29 527 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 77 524 1.1E-130 T 22-04-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 HRM2_RS00590 8b841287328c1df963c5c6a894ea6a29 527 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 40 524 1.1E-163 T 22-04-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 HRM2_RS00590 8b841287328c1df963c5c6a894ea6a29 527 PANTHER PTHR30047 6 527 1.5E-166 T 22-04-2016 HRM2_RS12625 2ea78778a966b164f63acdf04ae1ee7b 472 PANTHER PTHR33678 45 366 7.9E-80 T 22-04-2016 HRM2_RS12625 2ea78778a966b164f63acdf04ae1ee7b 472 PANTHER PTHR33678 382 458 7.9E-80 T 22-04-2016 HRM2_RS12625 2ea78778a966b164f63acdf04ae1ee7b 472 Pfam PF03050 Transposase IS66 family 157 434 1.4E-53 T 22-04-2016 IPR004291 Transposase, IS66 HRM2_RS12625 2ea78778a966b164f63acdf04ae1ee7b 472 PANTHER PTHR33678:SF2 45 366 7.9E-80 T 22-04-2016 HRM2_RS12625 2ea78778a966b164f63acdf04ae1ee7b 472 PANTHER PTHR33678:SF2 382 458 7.9E-80 T 22-04-2016 HRM2_RS18275 6f20ebd48e06a46df71c805db1cab288 88 Pfam PF01312 FlhB HrpN YscU SpaS Family 6 78 6.4E-20 T 22-04-2016 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HRM2_RS18275 6f20ebd48e06a46df71c805db1cab288 88 Gene3D G3DSA:3.40.1690.10 4 82 1.0E-25 T 22-04-2016 IPR029025 Type III secretion system substrate exporter, C-terminal HRM2_RS18275 6f20ebd48e06a46df71c805db1cab288 88 SUPERFAMILY SSF160544 4 82 9.29E-25 T 22-04-2016 IPR029025 Type III secretion system substrate exporter, C-terminal HRM2_RS18275 6f20ebd48e06a46df71c805db1cab288 88 PANTHER PTHR30531 4 86 5.4E-29 T 22-04-2016 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HRM2_RS13085 1811619e56ab6e5aafab645c7b91755b 230 Pfam PF01797 Transposase IS200 like 10 122 4.4E-17 T 22-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 HRM2_RS13085 1811619e56ab6e5aafab645c7b91755b 230 SUPERFAMILY SSF143422 2 127 1.11E-32 T 22-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 HRM2_RS13085 1811619e56ab6e5aafab645c7b91755b 230 SMART SM01321 9 124 7.3E-44 T 22-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 HRM2_RS13085 1811619e56ab6e5aafab645c7b91755b 230 PANTHER PTHR34322:SF1 2 143 1.0E-37 T 22-04-2016 HRM2_RS13085 1811619e56ab6e5aafab645c7b91755b 230 PANTHER PTHR34322 2 143 1.0E-37 T 22-04-2016 HRM2_RS13085 1811619e56ab6e5aafab645c7b91755b 230 Gene3D G3DSA:3.30.70.1290 6 127 3.7E-14 T 22-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 HRM2_RS07855 043a760c96efc23beb8bc8ee4659a0c5 491 Gene3D G3DSA:1.20.1600.10 139 478 4.4E-52 T 22-04-2016 HRM2_RS07855 043a760c96efc23beb8bc8ee4659a0c5 491 Gene3D G3DSA:1.20.1600.10 42 105 4.4E-52 T 22-04-2016 HRM2_RS07855 043a760c96efc23beb8bc8ee4659a0c5 491 SUPERFAMILY SSF56954 3 103 5.89E-66 T 22-04-2016 HRM2_RS07855 043a760c96efc23beb8bc8ee4659a0c5 491 SUPERFAMILY SSF56954 134 482 5.89E-66 T 22-04-2016 HRM2_RS07855 043a760c96efc23beb8bc8ee4659a0c5 491 PANTHER PTHR30026 41 485 1.6E-36 T 22-04-2016 HRM2_RS07855 043a760c96efc23beb8bc8ee4659a0c5 491 Pfam PF02321 Outer membrane efflux protein 294 481 1.5E-16 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS07855 043a760c96efc23beb8bc8ee4659a0c5 491 Pfam PF02321 Outer membrane efflux protein 46 270 1.2E-20 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS01385 d9cfc30d44f9a5940d3683e745ce3071 397 PANTHER PTHR24423 161 389 2.6E-18 T 22-04-2016 HRM2_RS01385 d9cfc30d44f9a5940d3683e745ce3071 397 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 184 303 1.0E-9 T 22-04-2016 IPR000014 PAS domain HRM2_RS01385 d9cfc30d44f9a5940d3683e745ce3071 397 Gene3D G3DSA:3.30.450.40 15 172 9.7E-23 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS01385 d9cfc30d44f9a5940d3683e745ce3071 397 Pfam PF13185 GAF domain 29 170 3.0E-14 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS01385 d9cfc30d44f9a5940d3683e745ce3071 397 Pfam PF00512 His Kinase A (phospho-acceptor) domain 315 374 1.5E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS01385 d9cfc30d44f9a5940d3683e745ce3071 397 Pfam PF13426 PAS domain 193 295 4.4E-7 T 22-04-2016 IPR000014 PAS domain HRM2_RS01385 d9cfc30d44f9a5940d3683e745ce3071 397 SUPERFAMILY SSF55785 170 295 1.48E-12 T 22-04-2016 IPR000014 PAS domain HRM2_RS01385 d9cfc30d44f9a5940d3683e745ce3071 397 SMART SM00065 29 179 0.0015 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS01385 d9cfc30d44f9a5940d3683e745ce3071 397 SUPERFAMILY SSF47384 306 375 1.12E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS01385 d9cfc30d44f9a5940d3683e745ce3071 397 Gene3D G3DSA:1.10.287.130 307 373 8.6E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS01385 d9cfc30d44f9a5940d3683e745ce3071 397 SUPERFAMILY SSF55781 14 186 1.13E-20 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS01385 d9cfc30d44f9a5940d3683e745ce3071 397 PANTHER PTHR24423:SF458 161 389 2.6E-18 T 22-04-2016 HRM2_RS01385 d9cfc30d44f9a5940d3683e745ce3071 397 Gene3D G3DSA:3.30.450.20 173 294 1.6E-13 T 22-04-2016 HRM2_RS01385 d9cfc30d44f9a5940d3683e745ce3071 397 SMART SM00388 312 378 8.8E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS01595 0638d959cd7c5581c21d22ab099ae07c 316 SUPERFAMILY SSF46894 247 305 5.44E-14 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HRM2_RS01595 0638d959cd7c5581c21d22ab099ae07c 316 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 288 300 3.8E-7 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS01595 0638d959cd7c5581c21d22ab099ae07c 316 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 258 272 3.8E-7 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS01595 0638d959cd7c5581c21d22ab099ae07c 316 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 272 288 3.8E-7 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS01595 0638d959cd7c5581c21d22ab099ae07c 316 Pfam PF00196 Bacterial regulatory proteins, luxR family 257 305 7.6E-12 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS01595 0638d959cd7c5581c21d22ab099ae07c 316 SMART SM00421 255 313 1.3E-10 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS01595 0638d959cd7c5581c21d22ab099ae07c 316 Gene3D G3DSA:1.10.10.10 257 305 2.8E-14 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS11070 439f5fcc84186fcc7014bd284fe03dd1 437 SUPERFAMILY SSF47384 210 283 5.69E-16 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS11070 439f5fcc84186fcc7014bd284fe03dd1 437 SMART SM00388 217 283 4.2E-17 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS11070 439f5fcc84186fcc7014bd284fe03dd1 437 SUPERFAMILY SSF103473 23 202 5.75E-5 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS11070 439f5fcc84186fcc7014bd284fe03dd1 437 Gene3D G3DSA:3.30.565.10 269 428 8.9E-39 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS11070 439f5fcc84186fcc7014bd284fe03dd1 437 PANTHER PTHR24423:SF445 201 428 4.9E-66 T 22-04-2016 HRM2_RS11070 439f5fcc84186fcc7014bd284fe03dd1 437 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 429 4.8E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS11070 439f5fcc84186fcc7014bd284fe03dd1 437 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 391 4.8E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS11070 439f5fcc84186fcc7014bd284fe03dd1 437 PRINTS PR00344 Bacterial sensor protein C-terminal signature 363 377 4.8E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS11070 439f5fcc84186fcc7014bd284fe03dd1 437 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 410 4.8E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS11070 439f5fcc84186fcc7014bd284fe03dd1 437 PANTHER PTHR24423 201 428 4.9E-66 T 22-04-2016 HRM2_RS11070 439f5fcc84186fcc7014bd284fe03dd1 437 SMART SM00387 325 432 4.8E-32 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS11070 439f5fcc84186fcc7014bd284fe03dd1 437 Pfam PF00512 His Kinase A (phospho-acceptor) domain 218 283 2.8E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS11070 439f5fcc84186fcc7014bd284fe03dd1 437 SUPERFAMILY SSF55874 274 428 3.54E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS11070 439f5fcc84186fcc7014bd284fe03dd1 437 Gene3D G3DSA:1.10.287.130 213 268 1.7E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS11070 439f5fcc84186fcc7014bd284fe03dd1 437 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 326 428 2.5E-22 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS17730 d747eccf2af9634c29da79b834312351 458 SUPERFAMILY SSF109604 175 439 3.38E-61 T 22-04-2016 HRM2_RS17730 d747eccf2af9634c29da79b834312351 458 PANTHER PTHR33525 173 439 2.8E-50 T 22-04-2016 HRM2_RS17730 d747eccf2af9634c29da79b834312351 458 Pfam PF08668 HDOD domain 185 381 4.5E-47 T 22-04-2016 IPR013976 Metal-dependent hydrolase HDOD HRM2_RS17730 d747eccf2af9634c29da79b834312351 458 Pfam PF03975 CheD chemotactic sensory transduction 50 154 1.8E-19 T 22-04-2016 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 HRM2_RS17730 d747eccf2af9634c29da79b834312351 458 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 1 159 20.667 T 22-04-2016 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 HRM2_RS17730 d747eccf2af9634c29da79b834312351 458 Gene3D G3DSA:1.10.3150.10 175 438 5.7E-64 T 22-04-2016 IPR013976 Metal-dependent hydrolase HDOD HRM2_RS17730 d747eccf2af9634c29da79b834312351 458 SUPERFAMILY SSF64438 8 158 8.06E-34 T 22-04-2016 IPR011324 Cytotoxic necrotizing factor-like, catalytic HRM2_RS17730 d747eccf2af9634c29da79b834312351 458 SMART SM00471 276 412 2.2E-4 T 22-04-2016 IPR003607 HD/PDEase domain HRM2_RS17730 d747eccf2af9634c29da79b834312351 458 PANTHER PTHR33525:SF3 173 439 2.8E-50 T 22-04-2016 HRM2_RS17730 d747eccf2af9634c29da79b834312351 458 TIGRFAM TIGR00277 HDIG: HDIG domain 278 379 1.9E-9 T 22-04-2016 IPR006675 HDIG domain HRM2_RS17725 064c0a8f09b6b828afa8bc0cdbc1d44f 244 PANTHER PTHR32119:SF2 5 243 1.5E-69 T 22-04-2016 HRM2_RS17725 064c0a8f09b6b828afa8bc0cdbc1d44f 244 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 7 230 5.2E-37 T 22-04-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 HRM2_RS17725 064c0a8f09b6b828afa8bc0cdbc1d44f 244 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 5 236 31.475 T 22-04-2016 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 HRM2_RS17725 064c0a8f09b6b828afa8bc0cdbc1d44f 244 Gene3D G3DSA:3.20.20.70 5 234 1.6E-69 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS17725 064c0a8f09b6b828afa8bc0cdbc1d44f 244 SUPERFAMILY SSF51366 4 239 3.46E-53 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 HRM2_RS17725 064c0a8f09b6b828afa8bc0cdbc1d44f 244 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 9 231 9.5E-52 T 22-04-2016 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 HRM2_RS17725 064c0a8f09b6b828afa8bc0cdbc1d44f 244 SMART SM00934 7 231 1.2E-61 T 22-04-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 HRM2_RS17725 064c0a8f09b6b828afa8bc0cdbc1d44f 244 PANTHER PTHR32119 5 243 1.5E-69 T 22-04-2016 HRM2_RS13990 04195fbb73c1a981434218fda4b8570e 437 PANTHER PTHR32479:SF13 10 421 3.2E-83 T 22-04-2016 HRM2_RS13990 04195fbb73c1a981434218fda4b8570e 437 Pfam PF02754 Cysteine-rich domain 323 406 5.5E-12 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS13990 04195fbb73c1a981434218fda4b8570e 437 Pfam PF02754 Cysteine-rich domain 188 271 6.1E-16 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS13990 04195fbb73c1a981434218fda4b8570e 437 PIRSF PIRSF000139 4 435 6.4E-86 T 22-04-2016 IPR012257 Glycolate oxidase, iron-sulphur subunit HRM2_RS13990 04195fbb73c1a981434218fda4b8570e 437 Pfam PF13183 4Fe-4S dicluster domain 21 86 4.8E-12 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS13990 04195fbb73c1a981434218fda4b8570e 437 Gene3D G3DSA:1.10.1060.10 16 101 1.8E-13 T 22-04-2016 HRM2_RS13990 04195fbb73c1a981434218fda4b8570e 437 SUPERFAMILY SSF46548 16 101 6.8E-15 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS13990 04195fbb73c1a981434218fda4b8570e 437 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 72 83 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS13990 04195fbb73c1a981434218fda4b8570e 437 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 21 32 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS13990 04195fbb73c1a981434218fda4b8570e 437 PANTHER PTHR32479 10 421 3.2E-83 T 22-04-2016 HRM2_RS17280 a721e14f27ccca0cd835bc2b7f2982dd 434 PANTHER PTHR33362:SF5 6 434 4.6E-143 T 22-04-2016 HRM2_RS17280 a721e14f27ccca0cd835bc2b7f2982dd 434 PANTHER PTHR33362 6 434 4.6E-143 T 22-04-2016 HRM2_RS17280 a721e14f27ccca0cd835bc2b7f2982dd 434 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 25 430 4.2E-88 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS17280 a721e14f27ccca0cd835bc2b7f2982dd 434 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 12 425 7.4E-93 T 22-04-2016 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit HRM2_RS17280 a721e14f27ccca0cd835bc2b7f2982dd 434 PIRSF PIRSF006066 6 434 4.1E-90 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS11555 07b0d28fd853874817aa9ea23edea75e 324 PANTHER PTHR10108 68 162 1.9E-14 T 22-04-2016 HRM2_RS11555 07b0d28fd853874817aa9ea23edea75e 324 Pfam PF13649 Methyltransferase domain 107 197 4.3E-14 T 22-04-2016 HRM2_RS11555 07b0d28fd853874817aa9ea23edea75e 324 SUPERFAMILY SSF53335 66 219 9.11E-22 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS11555 07b0d28fd853874817aa9ea23edea75e 324 Gene3D G3DSA:3.40.50.150 68 181 3.8E-19 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS25665 faa07448f23fe104e18f16bb736a6578 410 Gene3D G3DSA:3.90.1720.10 41 166 6.4E-41 T 22-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- HRM2_RS25665 faa07448f23fe104e18f16bb736a6578 410 SUPERFAMILY SSF56935 171 377 8.06E-6 T 22-04-2016 HRM2_RS25665 faa07448f23fe104e18f16bb736a6578 410 PANTHER PTHR21666 51 164 1.0E-32 T 22-04-2016 HRM2_RS25665 faa07448f23fe104e18f16bb736a6578 410 Gene3D G3DSA:2.40.170.20 273 377 3.4E-5 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 HRM2_RS25665 faa07448f23fe104e18f16bb736a6578 410 Pfam PF00877 NlpC/P60 family 56 163 1.1E-28 T 22-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- HRM2_RS25665 faa07448f23fe104e18f16bb736a6578 410 SUPERFAMILY SSF54001 37 166 6.28E-39 T 22-04-2016 HRM2_RS25485 d3cc8018b726746100ef59c2933af077 133 Gene3D G3DSA:3.30.160.170 45 129 9.4E-24 T 22-04-2016 IPR005186 FlaG protein HRM2_RS25485 d3cc8018b726746100ef59c2933af077 133 PANTHER PTHR37166:SF1 4 133 4.4E-19 T 22-04-2016 HRM2_RS25485 d3cc8018b726746100ef59c2933af077 133 PANTHER PTHR37166 4 133 4.4E-19 T 22-04-2016 HRM2_RS25485 d3cc8018b726746100ef59c2933af077 133 SUPERFAMILY SSF160214 42 131 2.09E-24 T 22-04-2016 IPR005186 FlaG protein HRM2_RS25485 d3cc8018b726746100ef59c2933af077 133 Pfam PF03646 FlaG protein 52 131 1.7E-22 T 22-04-2016 IPR005186 FlaG protein HRM2_RS01690 477908ed3b8939ebeca9ea10144edd3b 249 PANTHER PTHR11938:SF88 45 225 8.4E-26 T 22-04-2016 HRM2_RS01690 477908ed3b8939ebeca9ea10144edd3b 249 PANTHER PTHR11938:SF88 3 27 8.4E-26 T 22-04-2016 HRM2_RS01690 477908ed3b8939ebeca9ea10144edd3b 249 Gene3D G3DSA:3.30.70.20 84 142 2.2E-18 T 22-04-2016 HRM2_RS01690 477908ed3b8939ebeca9ea10144edd3b 249 PANTHER PTHR11938 45 225 8.4E-26 T 22-04-2016 HRM2_RS01690 477908ed3b8939ebeca9ea10144edd3b 249 PANTHER PTHR11938 3 27 8.4E-26 T 22-04-2016 HRM2_RS01690 477908ed3b8939ebeca9ea10144edd3b 249 SUPERFAMILY SSF54862 4 214 3.21E-39 T 22-04-2016 HRM2_RS01690 477908ed3b8939ebeca9ea10144edd3b 249 Pfam PF13247 4Fe-4S dicluster domain 68 172 3.7E-38 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS01690 477908ed3b8939ebeca9ea10144edd3b 249 PIRSF PIRSF036298 2 240 2.2E-49 T 22-04-2016 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 HRM2_RS01690 477908ed3b8939ebeca9ea10144edd3b 249 Gene3D G3DSA:3.30.70.20 4 83 9.8E-30 T 22-04-2016 HRM2_RS01690 477908ed3b8939ebeca9ea10144edd3b 249 Gene3D G3DSA:3.30.70.20 143 189 9.8E-30 T 22-04-2016 HRM2_RS07320 414b3137988c86c9202d8c996ad683ca 501 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 268 283 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS07320 414b3137988c86c9202d8c996ad683ca 501 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 206 219 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS07320 414b3137988c86c9202d8c996ad683ca 501 SUPERFAMILY SSF52540 182 431 5.17E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07320 414b3137988c86c9202d8c996ad683ca 501 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 399 408 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS07320 414b3137988c86c9202d8c996ad683ca 501 Pfam PF02954 Bacterial regulatory protein, Fis family 462 498 6.4E-6 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS07320 414b3137988c86c9202d8c996ad683ca 501 Gene3D G3DSA:3.40.50.300 178 354 1.2E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07320 414b3137988c86c9202d8c996ad683ca 501 SMART SM00382 202 345 3.0E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS07320 414b3137988c86c9202d8c996ad683ca 501 Pfam PF00158 Sigma-54 interaction domain 182 346 2.1E-68 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS07320 414b3137988c86c9202d8c996ad683ca 501 SUPERFAMILY SSF46689 450 501 8.06E-5 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS07320 414b3137988c86c9202d8c996ad683ca 501 Gene3D G3DSA:1.10.8.60 355 431 8.8E-19 T 22-04-2016 HRM2_RS07320 414b3137988c86c9202d8c996ad683ca 501 Gene3D G3DSA:1.10.10.60 454 501 1.1E-8 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS07320 414b3137988c86c9202d8c996ad683ca 501 PANTHER PTHR32071 157 501 1.3E-139 T 22-04-2016 HRM2_RS02425 b2eec7e793e2ce6a7abb53c18d020ff5 694 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 120 142 4.0263E-12 T 22-04-2016 HRM2_RS02425 b2eec7e793e2ce6a7abb53c18d020ff5 694 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 384 391 4.0263E-12 T 22-04-2016 HRM2_RS02425 b2eec7e793e2ce6a7abb53c18d020ff5 694 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 293 4.0263E-12 T 22-04-2016 HRM2_RS02425 b2eec7e793e2ce6a7abb53c18d020ff5 694 PANTHER PTHR22912:SF141 105 367 1.8E-53 T 22-04-2016 HRM2_RS02425 b2eec7e793e2ce6a7abb53c18d020ff5 694 SUPERFAMILY SSF54862 426 510 1.18E-9 T 22-04-2016 HRM2_RS02425 b2eec7e793e2ce6a7abb53c18d020ff5 694 SUPERFAMILY SSF51905 117 411 2.04E-32 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS02425 b2eec7e793e2ce6a7abb53c18d020ff5 694 Pfam PF00037 4Fe-4S binding domain 490 506 1.2E-4 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS02425 b2eec7e793e2ce6a7abb53c18d020ff5 694 Gene3D G3DSA:3.10.20.30 20 89 2.6E-7 T 22-04-2016 IPR012675 Beta-grasp domain HRM2_RS02425 b2eec7e793e2ce6a7abb53c18d020ff5 694 PANTHER PTHR22912 105 367 1.8E-53 T 22-04-2016 HRM2_RS02425 b2eec7e793e2ce6a7abb53c18d020ff5 694 Pfam PF04324 BFD-like [2Fe-2S] binding domain 608 657 1.5E-13 T 22-04-2016 IPR007419 BFD-like [2Fe-2S]-binding domain HRM2_RS02425 b2eec7e793e2ce6a7abb53c18d020ff5 694 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 63 71 - T 22-04-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 HRM2_RS02425 b2eec7e793e2ce6a7abb53c18d020ff5 694 Gene3D G3DSA:3.50.50.60 231 405 2.6E-19 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS02425 b2eec7e793e2ce6a7abb53c18d020ff5 694 Gene3D G3DSA:3.30.70.20 457 517 8.6E-10 T 22-04-2016 HRM2_RS02425 b2eec7e793e2ce6a7abb53c18d020ff5 694 SUPERFAMILY SSF54292 20 98 9.7E-14 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 HRM2_RS02425 b2eec7e793e2ce6a7abb53c18d020ff5 694 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 120 374 6.5E-25 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS02425 b2eec7e793e2ce6a7abb53c18d020ff5 694 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 121 140 9.791221E-18 T 22-04-2016 HRM2_RS02425 b2eec7e793e2ce6a7abb53c18d020ff5 694 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 268 286 9.791221E-18 T 22-04-2016 HRM2_RS02425 b2eec7e793e2ce6a7abb53c18d020ff5 694 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 358 374 9.791221E-18 T 22-04-2016 HRM2_RS02425 b2eec7e793e2ce6a7abb53c18d020ff5 694 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 224 242 9.791221E-18 T 22-04-2016 HRM2_RS02425 b2eec7e793e2ce6a7abb53c18d020ff5 694 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 18 96 4.7E-22 T 22-04-2016 HRM2_RS02425 b2eec7e793e2ce6a7abb53c18d020ff5 694 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 494 505 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS02425 b2eec7e793e2ce6a7abb53c18d020ff5 694 Gene3D G3DSA:3.50.50.60 119 230 2.0E-19 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS07035 00e7a98f9563fdd2127832be755aa2e0 345 Gene3D G3DSA:3.40.50.300 7 238 4.8E-83 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07035 00e7a98f9563fdd2127832be755aa2e0 345 SMART SM00382 32 215 8.2E-21 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS07035 00e7a98f9563fdd2127832be755aa2e0 345 Pfam PF00005 ABC transporter 24 165 8.7E-36 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS07035 00e7a98f9563fdd2127832be755aa2e0 345 SUPERFAMILY SSF50331 242 344 1.19E-12 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal HRM2_RS07035 00e7a98f9563fdd2127832be755aa2e0 345 PANTHER PTHR24220:SF150 9 303 2.4E-135 T 22-04-2016 HRM2_RS07035 00e7a98f9563fdd2127832be755aa2e0 345 PANTHER PTHR24220 9 303 2.4E-135 T 22-04-2016 HRM2_RS07035 00e7a98f9563fdd2127832be755aa2e0 345 Pfam PF08402 TOBE domain 273 343 1.3E-8 T 22-04-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 HRM2_RS07035 00e7a98f9563fdd2127832be755aa2e0 345 SUPERFAMILY SSF52540 8 247 6.01E-88 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13635 844f7d56a701a2d7504d7cfe4b0cbc7b 403 SUPERFAMILY SSF69864 174 398 2.49E-95 T 22-04-2016 HRM2_RS13635 844f7d56a701a2d7504d7cfe4b0cbc7b 403 PANTHER PTHR11587 1 402 2.4E-248 T 22-04-2016 HRM2_RS13635 844f7d56a701a2d7504d7cfe4b0cbc7b 403 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 118 129 - T 22-04-2016 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HRM2_RS13635 844f7d56a701a2d7504d7cfe4b0cbc7b 403 PANTHER PTHR11587:SF2 1 402 2.4E-248 T 22-04-2016 HRM2_RS13635 844f7d56a701a2d7504d7cfe4b0cbc7b 403 Gene3D G3DSA:3.90.1260.10 176 399 3.5E-102 T 22-04-2016 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HRM2_RS13635 844f7d56a701a2d7504d7cfe4b0cbc7b 403 Gene3D G3DSA:3.40.50.620 5 175 9.5E-69 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS13635 844f7d56a701a2d7504d7cfe4b0cbc7b 403 Pfam PF00764 Arginosuccinate synthase 8 393 3.2E-163 T 22-04-2016 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HRM2_RS13635 844f7d56a701a2d7504d7cfe4b0cbc7b 403 Hamap MF_00005 Argininosuccinate synthase [argG]. 4 399 52.314 T 22-04-2016 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HRM2_RS13635 844f7d56a701a2d7504d7cfe4b0cbc7b 403 TIGRFAM TIGR00032 argG: argininosuccinate synthase 6 393 1.2E-149 T 22-04-2016 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HRM2_RS13635 844f7d56a701a2d7504d7cfe4b0cbc7b 403 SUPERFAMILY SSF52402 5 206 1.26E-48 T 22-04-2016 HRM2_RS13635 844f7d56a701a2d7504d7cfe4b0cbc7b 403 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 10 18 - T 22-04-2016 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HRM2_RS03270 f1a3faef617bc1a05560898a13e75b1a 353 Gene3D G3DSA:3.40.50.10210 73 330 2.2E-106 T 22-04-2016 HRM2_RS03270 f1a3faef617bc1a05560898a13e75b1a 353 Gene3D G3DSA:1.10.1610.10 1 72 2.3E-26 T 22-04-2016 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 HRM2_RS03270 f1a3faef617bc1a05560898a13e75b1a 353 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 13 350 33.934 T 22-04-2016 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 HRM2_RS03270 f1a3faef617bc1a05560898a13e75b1a 353 PANTHER PTHR21712 8 352 1.5E-108 T 22-04-2016 HRM2_RS03270 f1a3faef617bc1a05560898a13e75b1a 353 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 15 347 1.0E-127 T 22-04-2016 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 HRM2_RS03270 f1a3faef617bc1a05560898a13e75b1a 353 PANTHER PTHR21712:SF4 8 352 1.5E-108 T 22-04-2016 HRM2_RS03270 f1a3faef617bc1a05560898a13e75b1a 353 Pfam PF02277 Phosphoribosyltransferase 11 346 1.4E-127 T 22-04-2016 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 HRM2_RS03270 f1a3faef617bc1a05560898a13e75b1a 353 SUPERFAMILY SSF52733 6 348 1.44E-109 T 22-04-2016 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 HRM2_RS07380 d2593c240e96c6f05609836e109731a5 856 Gene3D G3DSA:3.40.50.300 544 703 1.1E-10 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07380 d2593c240e96c6f05609836e109731a5 856 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 548 689 7.6E-5 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HRM2_RS07380 d2593c240e96c6f05609836e109731a5 856 SUPERFAMILY SSF52540 541 706 6.05E-14 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS15400 621bee1f54c20a4eb151fe2d1b8802e9 210 Gene3D G3DSA:3.40.50.1000 90 206 1.5E-32 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS15400 621bee1f54c20a4eb151fe2d1b8802e9 210 Gene3D G3DSA:3.40.50.1000 4 20 1.5E-32 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS15400 621bee1f54c20a4eb151fe2d1b8802e9 210 PANTHER PTHR18901 2 207 7.9E-36 T 22-04-2016 HRM2_RS15400 621bee1f54c20a4eb151fe2d1b8802e9 210 SUPERFAMILY SSF56784 6 206 1.01E-43 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS15400 621bee1f54c20a4eb151fe2d1b8802e9 210 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 6 17 1.1E-8 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HRM2_RS15400 621bee1f54c20a4eb151fe2d1b8802e9 210 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 99 112 1.1E-8 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HRM2_RS15400 621bee1f54c20a4eb151fe2d1b8802e9 210 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 147 167 1.1E-8 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HRM2_RS15400 621bee1f54c20a4eb151fe2d1b8802e9 210 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 129 145 1.1E-8 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HRM2_RS15400 621bee1f54c20a4eb151fe2d1b8802e9 210 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 184 1.8E-29 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS08510 6c1536c579b28b9e2dc34e11d9b55e25 198 Gene3D G3DSA:1.10.8.10 2 55 5.9E-26 T 22-04-2016 HRM2_RS08510 6c1536c579b28b9e2dc34e11d9b55e25 198 Gene3D G3DSA:3.30.479.20 57 111 1.4E-32 T 22-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 HRM2_RS08510 6c1536c579b28b9e2dc34e11d9b55e25 198 Gene3D G3DSA:3.30.479.20 157 198 1.4E-32 T 22-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 HRM2_RS08510 6c1536c579b28b9e2dc34e11d9b55e25 198 PANTHER PTHR11741 1 198 4.4E-92 T 22-04-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 HRM2_RS08510 6c1536c579b28b9e2dc34e11d9b55e25 198 SUPERFAMILY SSF54713 57 198 1.44E-52 T 22-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 HRM2_RS08510 6c1536c579b28b9e2dc34e11d9b55e25 198 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 22-04-2016 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 HRM2_RS08510 6c1536c579b28b9e2dc34e11d9b55e25 198 SUPERFAMILY SSF46934 4 55 3.06E-18 T 22-04-2016 IPR009060 UBA-like GO:0005515 HRM2_RS08510 6c1536c579b28b9e2dc34e11d9b55e25 198 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 96 8.9E-37 T 22-04-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 HRM2_RS08510 6c1536c579b28b9e2dc34e11d9b55e25 198 Hamap MF_00050 Elongation factor Ts [tsf]. 1 198 47.501 T 22-04-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 HRM2_RS08510 6c1536c579b28b9e2dc34e11d9b55e25 198 Gene3D G3DSA:1.10.286.20 112 155 2.2E-20 T 22-04-2016 HRM2_RS08510 6c1536c579b28b9e2dc34e11d9b55e25 198 Pfam PF00889 Elongation factor TS 55 198 4.7E-43 T 22-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 HRM2_RS09065 f31181b020d5e6cc5bff5d4f768fc905 149 PANTHER PTHR10739 1 130 2.2E-26 T 22-04-2016 HRM2_RS09065 f31181b020d5e6cc5bff5d4f768fc905 149 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 9 73 5.2E-16 T 22-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HRM2_RS09065 f31181b020d5e6cc5bff5d4f768fc905 149 SUPERFAMILY SSF52374 8 133 2.82E-22 T 22-04-2016 HRM2_RS09065 f31181b020d5e6cc5bff5d4f768fc905 149 Pfam PF01467 Cytidylyltransferase-like 11 100 1.0E-15 T 22-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HRM2_RS09065 f31181b020d5e6cc5bff5d4f768fc905 149 Gene3D G3DSA:3.40.50.620 7 124 4.2E-31 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS14610 1220ce46d379afd907eca6a4bcfa7012 328 Gene3D G3DSA:1.10.135.10 1 62 9.0E-23 T 22-04-2016 IPR022413 ATP:guanido phosphotransferase, N-terminal GO:0016301|GO:0016772 Reactome: REACT_13 HRM2_RS14610 1220ce46d379afd907eca6a4bcfa7012 328 Pfam PF02807 ATP:guanido phosphotransferase, N-terminal domain 1 61 1.8E-23 T 22-04-2016 IPR022413 ATP:guanido phosphotransferase, N-terminal GO:0016301|GO:0016772 Reactome: REACT_13 HRM2_RS14610 1220ce46d379afd907eca6a4bcfa7012 328 SUPERFAMILY SSF55931 84 326 1.04E-72 T 22-04-2016 HRM2_RS14610 1220ce46d379afd907eca6a4bcfa7012 328 Pfam PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain 84 326 1.9E-75 T 22-04-2016 IPR022414 ATP:guanido phosphotransferase, catalytic domain GO:0016301|GO:0016772 Reactome: REACT_13 HRM2_RS14610 1220ce46d379afd907eca6a4bcfa7012 328 Gene3D G3DSA:3.30.590.10 84 326 4.2E-83 T 22-04-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 HRM2_RS14610 1220ce46d379afd907eca6a4bcfa7012 328 ProSitePatterns PS00112 Phosphagen kinase active site signature. 243 249 - T 22-04-2016 IPR022415 ATP:guanido phosphotransferase active site GO:0016301|GO:0016772 Reactome: REACT_13 HRM2_RS14610 1220ce46d379afd907eca6a4bcfa7012 328 PANTHER PTHR11547 1 321 5.9E-117 T 22-04-2016 IPR000749 ATP:guanido phosphotransferase GO:0016772 Reactome: REACT_13 HRM2_RS14610 1220ce46d379afd907eca6a4bcfa7012 328 SUPERFAMILY SSF48034 1 62 6.8E-21 T 22-04-2016 IPR022413 ATP:guanido phosphotransferase, N-terminal GO:0016301|GO:0016772 Reactome: REACT_13 HRM2_RS11220 58a7ea29addea5707e7da53e384599df 362 Gene3D G3DSA:3.40.50.300 6 234 1.9E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11220 58a7ea29addea5707e7da53e384599df 362 SMART SM00382 28 211 4.2E-16 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS11220 58a7ea29addea5707e7da53e384599df 362 PANTHER PTHR24220:SF282 5 240 3.8E-105 T 22-04-2016 HRM2_RS11220 58a7ea29addea5707e7da53e384599df 362 Pfam PF08402 TOBE domain 291 345 4.1E-6 T 22-04-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 HRM2_RS11220 58a7ea29addea5707e7da53e384599df 362 PANTHER PTHR24220 5 240 3.8E-105 T 22-04-2016 HRM2_RS11220 58a7ea29addea5707e7da53e384599df 362 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS11220 58a7ea29addea5707e7da53e384599df 362 Pfam PF00005 ABC transporter 19 161 2.4E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS11220 58a7ea29addea5707e7da53e384599df 362 SUPERFAMILY SSF52540 6 241 6.69E-77 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11220 58a7ea29addea5707e7da53e384599df 362 SUPERFAMILY SSF50331 238 350 1.25E-5 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal HRM2_RS03865 dc32bc707dcc8018999d7242dffd9ddc 393 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 5 278 9.5E-48 T 22-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 HRM2_RS03865 dc32bc707dcc8018999d7242dffd9ddc 393 SUPERFAMILY SSF161111 3 198 9.42E-37 T 22-04-2016 HRM2_RS03865 dc32bc707dcc8018999d7242dffd9ddc 393 Gene3D G3DSA:3.30.420.130 277 387 5.9E-17 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS03865 dc32bc707dcc8018999d7242dffd9ddc 393 PANTHER PTHR11562:SF55 2 287 3.2E-50 T 22-04-2016 HRM2_RS03865 dc32bc707dcc8018999d7242dffd9ddc 393 Gene3D G3DSA:3.30.70.1350 199 276 7.6E-9 T 22-04-2016 IPR027470 Cation efflux protein, cytoplasmic domain HRM2_RS03865 dc32bc707dcc8018999d7242dffd9ddc 393 Pfam PF01545 Cation efflux family 9 197 1.5E-32 T 22-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 HRM2_RS03865 dc32bc707dcc8018999d7242dffd9ddc 393 PANTHER PTHR11562 2 287 3.2E-50 T 22-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 HRM2_RS03865 dc32bc707dcc8018999d7242dffd9ddc 393 SUPERFAMILY SSF160240 202 278 9.02E-9 T 22-04-2016 HRM2_RS03865 dc32bc707dcc8018999d7242dffd9ddc 393 Gene3D G3DSA:1.20.1510.10 5 197 2.3E-28 T 22-04-2016 IPR027469 Cation efflux protein transmembrane domain HRM2_RS03865 dc32bc707dcc8018999d7242dffd9ddc 393 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 294 388 3.2E-10 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS03865 dc32bc707dcc8018999d7242dffd9ddc 393 Pfam PF16916 Dimerisation domain of Zinc Transporter 209 277 1.5E-8 T 22-04-2016 IPR027470 Cation efflux protein, cytoplasmic domain HRM2_RS03865 dc32bc707dcc8018999d7242dffd9ddc 393 SUPERFAMILY SSF53146 286 387 3.53E-11 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS03015 d17a288491f838bfe66a3f4f946784ee 64 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 60 1.4E-10 T 22-04-2016 HRM2_RS03015 d17a288491f838bfe66a3f4f946784ee 64 SUPERFAMILY SSF54862 7 63 2.09E-6 T 22-04-2016 HRM2_RS03015 d17a288491f838bfe66a3f4f946784ee 64 Gene3D G3DSA:3.30.70.20 3 63 5.7E-11 T 22-04-2016 HRM2_RS08460 faf29cbdece34258bec99692cf1d8c4b 417 PANTHER PTHR12526 119 153 4.1E-66 T 22-04-2016 HRM2_RS08460 faf29cbdece34258bec99692cf1d8c4b 417 PANTHER PTHR12526 169 411 4.1E-66 T 22-04-2016 HRM2_RS08460 faf29cbdece34258bec99692cf1d8c4b 417 PANTHER PTHR12526 1 86 4.1E-66 T 22-04-2016 HRM2_RS08460 faf29cbdece34258bec99692cf1d8c4b 417 Pfam PF13439 Glycosyltransferase Family 4 19 222 9.3E-25 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain HRM2_RS08460 faf29cbdece34258bec99692cf1d8c4b 417 Pfam PF00534 Glycosyl transferases group 1 243 389 9.4E-31 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 HRM2_RS08460 faf29cbdece34258bec99692cf1d8c4b 417 Gene3D G3DSA:3.40.50.2000 205 388 6.9E-24 T 22-04-2016 HRM2_RS08460 faf29cbdece34258bec99692cf1d8c4b 417 SUPERFAMILY SSF53756 7 411 1.88E-77 T 22-04-2016 HRM2_RS07040 8d774f01cbd876b448a067ce17136e92 181 PANTHER PTHR11938 9 137 1.4E-21 T 22-04-2016 HRM2_RS07040 8d774f01cbd876b448a067ce17136e92 181 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 85 96 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS07040 8d774f01cbd876b448a067ce17136e92 181 Pfam PF12800 4Fe-4S binding domain 9 23 0.02 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS07040 8d774f01cbd876b448a067ce17136e92 181 Pfam PF13247 4Fe-4S dicluster domain 50 132 1.9E-11 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS07040 8d774f01cbd876b448a067ce17136e92 181 PANTHER PTHR11938:SF82 9 137 1.4E-21 T 22-04-2016 HRM2_RS07040 8d774f01cbd876b448a067ce17136e92 181 SUPERFAMILY SSF54862 9 144 1.51E-35 T 22-04-2016 HRM2_RS07040 8d774f01cbd876b448a067ce17136e92 181 Gene3D G3DSA:3.30.70.20 8 62 2.7E-8 T 22-04-2016 HRM2_RS07040 8d774f01cbd876b448a067ce17136e92 181 Gene3D G3DSA:3.30.70.20 91 148 5.5E-14 T 22-04-2016 HRM2_RS07040 8d774f01cbd876b448a067ce17136e92 181 Gene3D G3DSA:3.30.70.20 63 90 1.3E-13 T 22-04-2016 HRM2_RS24395 708197bdda23f242f1b35fc53d4b0ed9 786 Gene3D G3DSA:3.20.70.20 1 784 5.3E-241 T 22-04-2016 HRM2_RS24395 708197bdda23f242f1b35fc53d4b0ed9 786 PANTHER PTHR30191 1 786 0.0 T 22-04-2016 HRM2_RS24395 708197bdda23f242f1b35fc53d4b0ed9 786 PANTHER PTHR30191:SF6 1 786 0.0 T 22-04-2016 HRM2_RS24395 708197bdda23f242f1b35fc53d4b0ed9 786 SUPERFAMILY SSF51998 1 783 1.6E-221 T 22-04-2016 HRM2_RS24395 708197bdda23f242f1b35fc53d4b0ed9 786 Pfam PF01228 Glycine radical 665 767 3.8E-32 T 22-04-2016 IPR001150 Glycine radical domain GO:0003824|GO:0008152 HRM2_RS24395 708197bdda23f242f1b35fc53d4b0ed9 786 Pfam PF02901 Pyruvate formate lyase-like 2 648 4.5E-216 T 22-04-2016 IPR004184 Pyruvate formate lyase domain GO:0003824 HRM2_RS07030 54089e8fa72efc1ef47d07fbd4f8bbbc 301 PANTHER PTHR30193 20 296 1.2E-83 T 22-04-2016 HRM2_RS07030 54089e8fa72efc1ef47d07fbd4f8bbbc 301 PANTHER PTHR30193:SF10 20 296 1.2E-83 T 22-04-2016 HRM2_RS07030 54089e8fa72efc1ef47d07fbd4f8bbbc 301 Gene3D G3DSA:1.10.3720.10 24 295 1.0E-37 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS07030 54089e8fa72efc1ef47d07fbd4f8bbbc 301 SUPERFAMILY SSF161098 20 294 8.78E-42 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS14140 d1f8c4bb97e79c68c680624d8889741f 327 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS14140 d1f8c4bb97e79c68c680624d8889741f 327 SMART SM00382 35 238 8.6E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS14140 d1f8c4bb97e79c68c680624d8889741f 327 PANTHER PTHR24220:SF535 8 321 1.1E-141 T 22-04-2016 HRM2_RS14140 d1f8c4bb97e79c68c680624d8889741f 327 SUPERFAMILY SSF52540 6 257 4.33E-63 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14140 d1f8c4bb97e79c68c680624d8889741f 327 Gene3D G3DSA:3.40.50.300 5 260 1.7E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14140 d1f8c4bb97e79c68c680624d8889741f 327 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 236 322 5.1E-23 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HRM2_RS14140 d1f8c4bb97e79c68c680624d8889741f 327 PANTHER PTHR24220 8 321 1.1E-141 T 22-04-2016 HRM2_RS14140 d1f8c4bb97e79c68c680624d8889741f 327 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 303 6.9E-17 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HRM2_RS14140 d1f8c4bb97e79c68c680624d8889741f 327 Pfam PF00005 ABC transporter 27 186 5.7E-28 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS11735 091ac1b6971959a3b3ff99809e92f63b 677 PANTHER PTHR10357 17 673 3.5E-227 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 HRM2_RS11735 091ac1b6971959a3b3ff99809e92f63b 677 PANTHER PTHR10357:SF110 17 673 3.5E-227 T 22-04-2016 HRM2_RS11735 091ac1b6971959a3b3ff99809e92f63b 677 Gene3D G3DSA:2.60.40.10 50 148 8.7E-16 T 22-04-2016 IPR013783 Immunoglobulin-like fold HRM2_RS11735 091ac1b6971959a3b3ff99809e92f63b 677 Pfam PF00128 Alpha amylase, catalytic domain 203 274 2.1E-13 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HRM2_RS11735 091ac1b6971959a3b3ff99809e92f63b 677 SMART SM00642 189 550 2.5E-7 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HRM2_RS11735 091ac1b6971959a3b3ff99809e92f63b 677 Gene3D G3DSA:2.60.40.1180 584 673 9.7E-13 T 22-04-2016 IPR013780 Glycosyl hydrolase, all-beta HRM2_RS11735 091ac1b6971959a3b3ff99809e92f63b 677 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 584 673 4.7E-17 T 22-04-2016 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: REACT_474 HRM2_RS11735 091ac1b6971959a3b3ff99809e92f63b 677 Gene3D G3DSA:3.20.20.80 169 564 3.3E-71 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HRM2_RS11735 091ac1b6971959a3b3ff99809e92f63b 677 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 60 147 1.4E-8 T 22-04-2016 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 HRM2_RS11735 091ac1b6971959a3b3ff99809e92f63b 677 SUPERFAMILY SSF51445 156 573 6.79E-88 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily HRM2_RS11735 091ac1b6971959a3b3ff99809e92f63b 677 PIRSF PIRSF000463 13 677 7.2E-179 T 22-04-2016 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00164 HRM2_RS11735 091ac1b6971959a3b3ff99809e92f63b 677 SUPERFAMILY SSF81296 55 158 1.47E-13 T 22-04-2016 IPR014756 Immunoglobulin E-set HRM2_RS11735 091ac1b6971959a3b3ff99809e92f63b 677 SUPERFAMILY SSF51011 580 673 2.23E-14 T 22-04-2016 HRM2_RS22145 4b04329ae64f41831735dcc2cfb2e545 364 Pfam PF01966 HD domain 167 303 3.5E-18 T 22-04-2016 IPR006674 HD domain HRM2_RS22145 4b04329ae64f41831735dcc2cfb2e545 364 PANTHER PTHR26402 7 137 5.0E-55 T 22-04-2016 HRM2_RS22145 4b04329ae64f41831735dcc2cfb2e545 364 PANTHER PTHR26402 269 310 5.0E-55 T 22-04-2016 HRM2_RS22145 4b04329ae64f41831735dcc2cfb2e545 364 SMART SM00471 161 313 2.1E-9 T 22-04-2016 IPR003607 HD/PDEase domain HRM2_RS22145 4b04329ae64f41831735dcc2cfb2e545 364 PANTHER PTHR26402:SF495 7 137 5.0E-55 T 22-04-2016 HRM2_RS22145 4b04329ae64f41831735dcc2cfb2e545 364 PANTHER PTHR26402:SF495 269 310 5.0E-55 T 22-04-2016 HRM2_RS22145 4b04329ae64f41831735dcc2cfb2e545 364 Gene3D G3DSA:1.10.3210.10 162 346 5.2E-19 T 22-04-2016 IPR006674 HD domain HRM2_RS22145 4b04329ae64f41831735dcc2cfb2e545 364 SMART SM00448 7 119 2.1E-30 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS22145 4b04329ae64f41831735dcc2cfb2e545 364 SUPERFAMILY SSF109604 156 342 4.71E-31 T 22-04-2016 HRM2_RS22145 4b04329ae64f41831735dcc2cfb2e545 364 Pfam PF00072 Response regulator receiver domain 9 119 2.8E-24 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS22145 4b04329ae64f41831735dcc2cfb2e545 364 SUPERFAMILY SSF52172 4 136 7.83E-36 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS22145 4b04329ae64f41831735dcc2cfb2e545 364 Gene3D G3DSA:3.40.50.2300 6 132 3.2E-37 T 22-04-2016 HRM2_RS12260 ce8faadc7730721745fd86ac153decf9 147 PRINTS PR01438 Universal stress protein signature 122 144 1.5E-14 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS12260 ce8faadc7730721745fd86ac153decf9 147 PRINTS PR01438 Universal stress protein signature 104 116 1.5E-14 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS12260 ce8faadc7730721745fd86ac153decf9 147 PRINTS PR01438 Universal stress protein signature 3 21 1.5E-14 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS12260 ce8faadc7730721745fd86ac153decf9 147 Gene3D G3DSA:3.40.50.620 1 146 3.7E-35 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS12260 ce8faadc7730721745fd86ac153decf9 147 Pfam PF00582 Universal stress protein family 3 144 2.1E-28 T 22-04-2016 IPR006016 UspA GO:0006950 HRM2_RS12260 ce8faadc7730721745fd86ac153decf9 147 SUPERFAMILY SSF52402 1 145 1.88E-34 T 22-04-2016 HRM2_RS12260 ce8faadc7730721745fd86ac153decf9 147 PANTHER PTHR31964 1 147 1.1E-26 T 22-04-2016 HRM2_RS12260 ce8faadc7730721745fd86ac153decf9 147 PIRSF PIRSF006276 1 147 2.0E-18 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS00665 8a26e96591dde06972cb5f92d564860d 392 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 137 385 8.1E-37 T 22-04-2016 IPR032095 Saccharopine dehydrogenase, C-terminal HRM2_RS00665 8a26e96591dde06972cb5f92d564860d 392 SUPERFAMILY SSF51735 2 183 7.04E-18 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS00665 8a26e96591dde06972cb5f92d564860d 392 PANTHER PTHR12286:SF6 1 389 1.2E-166 T 22-04-2016 HRM2_RS00665 8a26e96591dde06972cb5f92d564860d 392 PANTHER PTHR12286 1 389 1.2E-166 T 22-04-2016 HRM2_RS00665 8a26e96591dde06972cb5f92d564860d 392 Gene3D G3DSA:3.40.50.720 2 186 7.3E-33 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS00665 8a26e96591dde06972cb5f92d564860d 392 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 4 133 1.2E-34 T 22-04-2016 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 HRM2_RS06060 b674510cb7bc9dcf00e29f3af22d0ba9 434 PIRSF PIRSF006066 6 434 1.3E-97 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS06060 b674510cb7bc9dcf00e29f3af22d0ba9 434 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 11 423 5.2E-93 T 22-04-2016 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit HRM2_RS06060 b674510cb7bc9dcf00e29f3af22d0ba9 434 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 21 429 8.9E-94 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS06060 b674510cb7bc9dcf00e29f3af22d0ba9 434 PANTHER PTHR33362 8 433 7.8E-144 T 22-04-2016 HRM2_RS06060 b674510cb7bc9dcf00e29f3af22d0ba9 434 PANTHER PTHR33362:SF5 8 433 7.8E-144 T 22-04-2016 HRM2_RS17190 aa78093ac89931836e275e08ef06cb05 316 Pfam PF00586 AIR synthase related protein, N-terminal domain 18 124 1.2E-16 T 22-04-2016 IPR016188 PurM-like, N-terminal domain HRM2_RS17190 aa78093ac89931836e275e08ef06cb05 316 Gene3D G3DSA:3.90.650.10 142 314 7.8E-20 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain HRM2_RS17190 aa78093ac89931836e275e08ef06cb05 316 PANTHER PTHR10256 6 316 2.8E-104 T 22-04-2016 HRM2_RS17190 aa78093ac89931836e275e08ef06cb05 316 SUPERFAMILY SSF55326 5 128 1.48E-36 T 22-04-2016 HRM2_RS17190 aa78093ac89931836e275e08ef06cb05 316 TIGRFAM TIGR00476 selD: selenide, water dikinase 5 283 8.2E-106 T 22-04-2016 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 HRM2_RS17190 aa78093ac89931836e275e08ef06cb05 316 Pfam PF02769 AIR synthase related protein, C-terminal domain 137 313 5.3E-29 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain HRM2_RS17190 aa78093ac89931836e275e08ef06cb05 316 SUPERFAMILY SSF56042 131 308 3.44E-49 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain HRM2_RS17190 aa78093ac89931836e275e08ef06cb05 316 Gene3D G3DSA:3.30.1330.10 6 129 2.1E-26 T 22-04-2016 IPR016188 PurM-like, N-terminal domain HRM2_RS17190 aa78093ac89931836e275e08ef06cb05 316 PIRSF PIRSF036407 1 316 3.4E-113 T 22-04-2016 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 HRM2_RS17190 aa78093ac89931836e275e08ef06cb05 316 Hamap MF_00625 Selenide, water dikinase [selD]. 1 316 35.006 T 22-04-2016 IPR023061 Selenophosphate synthetase, class I GO:0004756|GO:0005524|GO:0016260 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 HRM2_RS23375 aa8266fa0c5d25a5d2ad9eda8021687f 261 Pfam PF02361 Cobalt transport protein 15 230 8.1E-27 T 22-04-2016 IPR003339 ABC/ECF transporter, transmembrane component HRM2_RS23375 aa8266fa0c5d25a5d2ad9eda8021687f 261 PANTHER PTHR33514 9 260 2.6E-32 T 22-04-2016 HRM2_RS23375 aa8266fa0c5d25a5d2ad9eda8021687f 261 PANTHER PTHR33514:SF4 9 260 2.6E-32 T 22-04-2016 HRM2_RS22300 49939c1b83a049bedc8f006aa2bc676f 392 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 13 382 3.4E-112 T 22-04-2016 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 HRM2_RS22300 49939c1b83a049bedc8f006aa2bc676f 392 PANTHER PTHR10361 13 113 4.7E-123 T 22-04-2016 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 HRM2_RS22300 49939c1b83a049bedc8f006aa2bc676f 392 PANTHER PTHR10361 161 392 4.7E-123 T 22-04-2016 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 HRM2_RS22300 49939c1b83a049bedc8f006aa2bc676f 392 PANTHER PTHR10361:SF31 13 113 4.7E-123 T 22-04-2016 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 HRM2_RS22300 49939c1b83a049bedc8f006aa2bc676f 392 PANTHER PTHR10361:SF31 161 392 4.7E-123 T 22-04-2016 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 HRM2_RS22300 49939c1b83a049bedc8f006aa2bc676f 392 Pfam PF01758 Sodium Bile acid symporter family 62 295 5.1E-48 T 22-04-2016 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 HRM2_RS22300 49939c1b83a049bedc8f006aa2bc676f 392 PIRSF PIRSF005508 3 392 8.8E-117 T 22-04-2016 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 HRM2_RS15730 53ed0ee30f62bf02a2cdc16f14440cb9 489 Gene3D G3DSA:1.25.40.10 277 449 1.3E-19 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS15730 53ed0ee30f62bf02a2cdc16f14440cb9 489 SUPERFAMILY SSF48452 277 444 1.48E-16 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS15730 53ed0ee30f62bf02a2cdc16f14440cb9 489 Gene3D G3DSA:3.30.2010.10 64 134 2.0E-15 T 22-04-2016 HRM2_RS15730 53ed0ee30f62bf02a2cdc16f14440cb9 489 SMART SM00028 417 450 96.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS15730 53ed0ee30f62bf02a2cdc16f14440cb9 489 SMART SM00028 365 398 17.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS15730 53ed0ee30f62bf02a2cdc16f14440cb9 489 SMART SM00028 297 330 24.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS15730 53ed0ee30f62bf02a2cdc16f14440cb9 489 Pfam PF01435 Peptidase family M48 73 246 2.4E-27 T 22-04-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 HRM2_RS15730 53ed0ee30f62bf02a2cdc16f14440cb9 489 PANTHER PTHR22726 29 339 7.5E-47 T 22-04-2016 HRM2_RS15730 53ed0ee30f62bf02a2cdc16f14440cb9 489 PANTHER PTHR22726:SF10 29 339 7.5E-47 T 22-04-2016 HRM2_RS25230 7eadcc081d1ae2031acb4c7d7604a1e0 82 SUPERFAMILY SSF51735 3 78 8.63E-18 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS25230 7eadcc081d1ae2031acb4c7d7604a1e0 82 PANTHER PTHR24320:SF45 1 78 3.9E-15 T 22-04-2016 HRM2_RS25230 7eadcc081d1ae2031acb4c7d7604a1e0 82 Gene3D G3DSA:3.40.50.720 2 78 9.6E-19 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS25230 7eadcc081d1ae2031acb4c7d7604a1e0 82 PANTHER PTHR24320 1 78 3.9E-15 T 22-04-2016 HRM2_RS25230 7eadcc081d1ae2031acb4c7d7604a1e0 82 Pfam PF00106 short chain dehydrogenase 3 78 1.2E-11 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS07825 13cc5051849c2e15152563a5c67ca09b 282 SUPERFAMILY SSF53850 37 281 1.09E-41 T 22-04-2016 HRM2_RS07825 13cc5051849c2e15152563a5c67ca09b 282 Gene3D G3DSA:3.40.190.10 37 159 1.7E-19 T 22-04-2016 HRM2_RS07825 13cc5051849c2e15152563a5c67ca09b 282 Pfam PF12849 PBP superfamily domain 29 267 6.7E-31 T 22-04-2016 IPR024370 PBP domain HRM2_RS07825 13cc5051849c2e15152563a5c67ca09b 282 PANTHER PTHR30570 4 281 1.6E-23 T 22-04-2016 HRM2_RS02215 36d175cebf3889a49e9a552693329434 778 Gene3D G3DSA:3.50.50.60 140 239 1.7E-35 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS02215 36d175cebf3889a49e9a552693329434 778 Gene3D G3DSA:3.50.50.60 399 564 1.7E-35 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS02215 36d175cebf3889a49e9a552693329434 778 Gene3D G3DSA:3.50.50.60 317 345 1.7E-35 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS02215 36d175cebf3889a49e9a552693329434 778 SUPERFAMILY SSF54862 562 625 1.07E-15 T 22-04-2016 HRM2_RS02215 36d175cebf3889a49e9a552693329434 778 Pfam PF13187 4Fe-4S dicluster domain 568 613 6.5E-7 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS02215 36d175cebf3889a49e9a552693329434 778 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 172 1.2E-6 T 22-04-2016 HRM2_RS02215 36d175cebf3889a49e9a552693329434 778 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 513 520 1.2E-6 T 22-04-2016 HRM2_RS02215 36d175cebf3889a49e9a552693329434 778 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 459 473 1.2E-6 T 22-04-2016 HRM2_RS02215 36d175cebf3889a49e9a552693329434 778 Pfam PF13450 NAD(P)-binding Rossmann-like domain 153 191 8.1E-8 T 22-04-2016 HRM2_RS02215 36d175cebf3889a49e9a552693329434 778 SUPERFAMILY SSF51905 414 575 1.29E-27 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS02215 36d175cebf3889a49e9a552693329434 778 SUPERFAMILY SSF51905 135 225 1.29E-27 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS02215 36d175cebf3889a49e9a552693329434 778 SUPERFAMILY SSF51905 304 358 1.29E-27 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS02215 36d175cebf3889a49e9a552693329434 778 PANTHER PTHR10742:SF297 522 530 3.2E-23 T 22-04-2016 HRM2_RS02215 36d175cebf3889a49e9a552693329434 778 PANTHER PTHR10742:SF297 56 249 3.2E-23 T 22-04-2016 HRM2_RS02215 36d175cebf3889a49e9a552693329434 778 PANTHER PTHR10742:SF297 296 365 3.2E-23 T 22-04-2016 HRM2_RS02215 36d175cebf3889a49e9a552693329434 778 Pfam PF02662 Methyl-viologen-reducing hydrogenase, delta subunit 646 771 1.3E-41 T 22-04-2016 IPR003813 Methyl-viologen-reducing hydrogenase, delta subunit GO:0015948|GO:0055114 HRM2_RS02215 36d175cebf3889a49e9a552693329434 778 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 569 580 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS02215 36d175cebf3889a49e9a552693329434 778 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 599 610 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS02215 36d175cebf3889a49e9a552693329434 778 Gene3D G3DSA:3.30.70.20 565 619 5.3E-16 T 22-04-2016 HRM2_RS02215 36d175cebf3889a49e9a552693329434 778 PANTHER PTHR10742 522 530 3.2E-23 T 22-04-2016 HRM2_RS02215 36d175cebf3889a49e9a552693329434 778 PANTHER PTHR10742 56 249 3.2E-23 T 22-04-2016 HRM2_RS02215 36d175cebf3889a49e9a552693329434 778 PANTHER PTHR10742 296 365 3.2E-23 T 22-04-2016 HRM2_RS06080 d5c0c72df80fa69a1b282d6bbfccf547 259 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 50 63 - T 22-04-2016 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 HRM2_RS06080 d5c0c72df80fa69a1b282d6bbfccf547 259 PANTHER PTHR18966:SF152 8 252 2.4E-70 T 22-04-2016 HRM2_RS06080 d5c0c72df80fa69a1b282d6bbfccf547 259 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 28 253 1.0E-69 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS06080 d5c0c72df80fa69a1b282d6bbfccf547 259 Gene3D G3DSA:3.40.190.10 214 256 1.1E-48 T 22-04-2016 HRM2_RS06080 d5c0c72df80fa69a1b282d6bbfccf547 259 Gene3D G3DSA:3.40.190.10 27 113 1.1E-48 T 22-04-2016 HRM2_RS06080 d5c0c72df80fa69a1b282d6bbfccf547 259 PANTHER PTHR18966 8 252 2.4E-70 T 22-04-2016 HRM2_RS06080 d5c0c72df80fa69a1b282d6bbfccf547 259 SUPERFAMILY SSF53850 1 256 1.34E-71 T 22-04-2016 HRM2_RS06080 d5c0c72df80fa69a1b282d6bbfccf547 259 SMART SM00062 27 255 9.5E-77 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS06080 d5c0c72df80fa69a1b282d6bbfccf547 259 Gene3D G3DSA:3.40.190.10 117 212 8.5E-29 T 22-04-2016 HRM2_RS06080 d5c0c72df80fa69a1b282d6bbfccf547 259 TIGRFAM TIGR01096 3A0103s03R: lysine-arginine-ornithine-binding periplasmic protein 4 252 2.5E-86 T 22-04-2016 IPR005768 Lysine-arginine-ornithine-binding periplasmic protein GO:0005215|GO:0006810|GO:0030288 HRM2_RS05535 c12c506b554b55c5160a11551a85b927 310 Gene3D G3DSA:3.55.30.10 20 251 1.3E-61 T 22-04-2016 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 HRM2_RS05535 c12c506b554b55c5160a11551a85b927 310 SUPERFAMILY SSF64397 20 258 3.53E-56 T 22-04-2016 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 HRM2_RS05535 c12c506b554b55c5160a11551a85b927 310 PANTHER PTHR30111 21 305 2.4E-61 T 22-04-2016 HRM2_RS05535 c12c506b554b55c5160a11551a85b927 310 PANTHER PTHR30111:SF1 21 305 2.4E-61 T 22-04-2016 HRM2_RS05535 c12c506b554b55c5160a11551a85b927 310 SUPERFAMILY SSF118352 250 305 5.1E-12 T 22-04-2016 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 HRM2_RS05535 c12c506b554b55c5160a11551a85b927 310 Gene3D G3DSA:3.90.1280.10 252 305 1.3E-15 T 22-04-2016 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 HRM2_RS05535 c12c506b554b55c5160a11551a85b927 310 PIRSF PIRSF005261 10 308 5.6E-70 T 22-04-2016 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 HRM2_RS05535 c12c506b554b55c5160a11551a85b927 310 Pfam PF01430 Hsp33 protein 21 298 3.6E-75 T 22-04-2016 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 HRM2_RS08715 fb95e3f74fd066b4a674c45b122ca93f 298 SUPERFAMILY SSF82861 30 112 2.48E-12 T 22-04-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 HRM2_RS08715 fb95e3f74fd066b4a674c45b122ca93f 298 Gene3D G3DSA:3.30.70.100 182 267 1.8E-15 T 22-04-2016 HRM2_RS08715 fb95e3f74fd066b4a674c45b122ca93f 298 SUPERFAMILY SSF50182 113 179 4.25E-16 T 22-04-2016 IPR010920 LSM domain HRM2_RS08715 fb95e3f74fd066b4a674c45b122ca93f 298 Gene3D G3DSA:2.30.30.60 129 176 1.2E-14 T 22-04-2016 HRM2_RS08715 fb95e3f74fd066b4a674c45b122ca93f 298 SUPERFAMILY SSF82689 181 276 2.35E-18 T 22-04-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 HRM2_RS08715 fb95e3f74fd066b4a674c45b122ca93f 298 Pfam PF00924 Mechanosensitive ion channel 71 269 2.2E-43 T 22-04-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 HRM2_RS08715 fb95e3f74fd066b4a674c45b122ca93f 298 PANTHER PTHR30221 21 290 8.7E-53 T 22-04-2016 HRM2_RS09205 04e1f91e7530bd3010b3d653c366b11c 253 Gene3D G3DSA:3.40.1280.10 101 250 2.5E-45 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HRM2_RS09205 04e1f91e7530bd3010b3d653c366b11c 253 PANTHER PTHR12029 3 249 5.9E-67 T 22-04-2016 HRM2_RS09205 04e1f91e7530bd3010b3d653c366b11c 253 Pfam PF00588 SpoU rRNA Methylase family 103 243 5.9E-32 T 22-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 HRM2_RS09205 04e1f91e7530bd3010b3d653c366b11c 253 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 10 83 1.0E-18 T 22-04-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 HRM2_RS09205 04e1f91e7530bd3010b3d653c366b11c 253 Gene3D G3DSA:3.30.1330.30 3 82 2.8E-22 T 22-04-2016 IPR029064 50S ribosomal protein L30e-like HRM2_RS09205 04e1f91e7530bd3010b3d653c366b11c 253 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 9 249 3.8E-63 T 22-04-2016 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 HRM2_RS09205 04e1f91e7530bd3010b3d653c366b11c 253 SUPERFAMILY SSF75217 99 250 2.16E-40 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases HRM2_RS09205 04e1f91e7530bd3010b3d653c366b11c 253 SMART SM00967 10 86 9.8E-20 T 22-04-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 HRM2_RS09205 04e1f91e7530bd3010b3d653c366b11c 253 SUPERFAMILY SSF55315 5 83 4.12E-19 T 22-04-2016 IPR029064 50S ribosomal protein L30e-like HRM2_RS11235 2cdc993acf14d8db17dd602a11b40f54 657 Pfam PF00027 Cyclic nucleotide-binding domain 44 130 1.5E-21 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain HRM2_RS11235 2cdc993acf14d8db17dd602a11b40f54 657 Gene3D G3DSA:3.40.1090.10 395 554 8.0E-7 T 22-04-2016 HRM2_RS11235 2cdc993acf14d8db17dd602a11b40f54 657 SMART SM00100 25 142 1.1E-23 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain HRM2_RS11235 2cdc993acf14d8db17dd602a11b40f54 657 PANTHER PTHR14226 356 649 8.4E-66 T 22-04-2016 HRM2_RS11235 2cdc993acf14d8db17dd602a11b40f54 657 PANTHER PTHR14226:SF24 356 649 8.4E-66 T 22-04-2016 HRM2_RS11235 2cdc993acf14d8db17dd602a11b40f54 657 Pfam PF01734 Patatin-like phospholipase 395 557 3.3E-20 T 22-04-2016 IPR002641 Patatin/Phospholipase A2-related GO:0006629 HRM2_RS11235 2cdc993acf14d8db17dd602a11b40f54 657 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 92 109 - T 22-04-2016 IPR018488 Cyclic nucleotide-binding, conserved site HRM2_RS11235 2cdc993acf14d8db17dd602a11b40f54 657 SUPERFAMILY SSF52151 391 605 3.92E-47 T 22-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 HRM2_RS11235 2cdc993acf14d8db17dd602a11b40f54 657 Gene3D G3DSA:2.60.120.10 13 146 2.0E-33 T 22-04-2016 IPR014710 RmlC-like jelly roll fold HRM2_RS11235 2cdc993acf14d8db17dd602a11b40f54 657 PRINTS PR00103 cAMP-dependent protein kinase signature 316 328 3.5E-5 T 22-04-2016 HRM2_RS11235 2cdc993acf14d8db17dd602a11b40f54 657 PRINTS PR00103 cAMP-dependent protein kinase signature 61 75 3.5E-5 T 22-04-2016 HRM2_RS11235 2cdc993acf14d8db17dd602a11b40f54 657 PRINTS PR00103 cAMP-dependent protein kinase signature 90 99 3.5E-5 T 22-04-2016 HRM2_RS11235 2cdc993acf14d8db17dd602a11b40f54 657 PRINTS PR00103 cAMP-dependent protein kinase signature 46 60 3.5E-5 T 22-04-2016 HRM2_RS11235 2cdc993acf14d8db17dd602a11b40f54 657 SUPERFAMILY SSF51206 18 148 7.2E-32 T 22-04-2016 IPR018490 Cyclic nucleotide-binding-like HRM2_RS11235 2cdc993acf14d8db17dd602a11b40f54 657 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 52 68 - T 22-04-2016 IPR018488 Cyclic nucleotide-binding, conserved site HRM2_RS00440 80168ab0b8294212e69e02d3992e647b 483 Pfam PF02321 Outer membrane efflux protein 284 465 4.2E-21 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS00440 80168ab0b8294212e69e02d3992e647b 483 Pfam PF02321 Outer membrane efflux protein 74 259 4.5E-21 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS00440 80168ab0b8294212e69e02d3992e647b 483 PANTHER PTHR30203:SF3 5 469 3.9E-78 T 22-04-2016 HRM2_RS00440 80168ab0b8294212e69e02d3992e647b 483 PANTHER PTHR30203 5 469 3.9E-78 T 22-04-2016 HRM2_RS00440 80168ab0b8294212e69e02d3992e647b 483 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 28 467 5.1E-90 T 22-04-2016 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 HRM2_RS00440 80168ab0b8294212e69e02d3992e647b 483 SUPERFAMILY SSF56954 18 468 1.57E-91 T 22-04-2016 HRM2_RS00440 80168ab0b8294212e69e02d3992e647b 483 Gene3D G3DSA:1.20.1600.10 64 468 3.3E-93 T 22-04-2016 HRM2_RS17005 eeaf24eb663b9cc325ce40c7c26f3cff 282 Pfam PF08668 HDOD domain 15 208 2.9E-53 T 22-04-2016 IPR013976 Metal-dependent hydrolase HDOD HRM2_RS17005 eeaf24eb663b9cc325ce40c7c26f3cff 282 PANTHER PTHR33525 3 281 7.9E-58 T 22-04-2016 HRM2_RS17005 eeaf24eb663b9cc325ce40c7c26f3cff 282 TIGRFAM TIGR00277 HDIG: HDIG domain 113 208 2.9E-7 T 22-04-2016 IPR006675 HDIG domain HRM2_RS17005 eeaf24eb663b9cc325ce40c7c26f3cff 282 SUPERFAMILY SSF109604 4 268 1.37E-64 T 22-04-2016 HRM2_RS17005 eeaf24eb663b9cc325ce40c7c26f3cff 282 Gene3D G3DSA:1.10.3150.10 4 269 3.9E-72 T 22-04-2016 IPR013976 Metal-dependent hydrolase HDOD HRM2_RS17005 eeaf24eb663b9cc325ce40c7c26f3cff 282 PANTHER PTHR33525:SF3 3 281 7.9E-58 T 22-04-2016 HRM2_RS15080 f8923498b43c7fcec3a58400c9d6efe7 197 Gene3D G3DSA:3.30.1330.60 90 196 2.9E-32 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS15080 f8923498b43c7fcec3a58400c9d6efe7 197 SUPERFAMILY SSF103088 89 196 4.71E-33 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS15080 f8923498b43c7fcec3a58400c9d6efe7 197 Pfam PF00691 OmpA family 96 190 2.3E-18 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS15080 f8923498b43c7fcec3a58400c9d6efe7 197 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 94 195 1.2E-37 T 22-04-2016 IPR014169 Peptidoglycan-associated lipoprotein GO:0009279 HRM2_RS15080 f8923498b43c7fcec3a58400c9d6efe7 197 PANTHER PTHR30128:SF18 91 197 1.1E-44 T 22-04-2016 HRM2_RS15080 f8923498b43c7fcec3a58400c9d6efe7 197 PRINTS PR01021 OMPA domain signature 96 118 2.0E-11 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 HRM2_RS15080 f8923498b43c7fcec3a58400c9d6efe7 197 PRINTS PR01021 OMPA domain signature 126 141 2.0E-11 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 HRM2_RS15080 f8923498b43c7fcec3a58400c9d6efe7 197 PRINTS PR01021 OMPA domain signature 141 157 2.0E-11 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 HRM2_RS15080 f8923498b43c7fcec3a58400c9d6efe7 197 PANTHER PTHR30128 91 197 1.1E-44 T 22-04-2016 HRM2_RS05320 69477a7b691895e5361f1ea717c83478 194 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 7 188 1.3E-69 T 22-04-2016 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0000917|GO:0005525 HRM2_RS05320 69477a7b691895e5361f1ea717c83478 194 Pfam PF01926 50S ribosome-binding GTPase 25 143 4.1E-21 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS05320 69477a7b691895e5361f1ea717c83478 194 PANTHER PTHR11649 3 194 9.1E-54 T 22-04-2016 HRM2_RS05320 69477a7b691895e5361f1ea717c83478 194 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 11 192 27.617 T 22-04-2016 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0000917|GO:0005525 HRM2_RS05320 69477a7b691895e5361f1ea717c83478 194 SUPERFAMILY SSF52540 24 192 3.57E-36 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05320 69477a7b691895e5361f1ea717c83478 194 Gene3D G3DSA:3.40.50.300 8 192 6.1E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05320 69477a7b691895e5361f1ea717c83478 194 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 26 159 6.8E-13 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HRM2_RS23825 0077f83bcafde6be95881a3704998ee5 324 PANTHER PTHR33376 1 322 1.1E-79 T 22-04-2016 HRM2_RS23825 0077f83bcafde6be95881a3704998ee5 324 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 29 273 2.0E-70 T 22-04-2016 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 HRM2_RS23825 0077f83bcafde6be95881a3704998ee5 324 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 28 301 3.8E-82 T 22-04-2016 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 HRM2_RS23825 0077f83bcafde6be95881a3704998ee5 324 PANTHER PTHR33376:SF2 1 322 1.1E-79 T 22-04-2016 HRM2_RS23825 0077f83bcafde6be95881a3704998ee5 324 PIRSF PIRSF006470 1 324 7.2E-93 T 22-04-2016 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 HRM2_RS14350 571c87b43caa862e2f29b2dca9368f3e 571 SUPERFAMILY SSF52518 1 163 1.52E-49 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS14350 571c87b43caa862e2f29b2dca9368f3e 571 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 168 6.6E-54 T 22-04-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 HRM2_RS14350 571c87b43caa862e2f29b2dca9368f3e 571 Gene3D G3DSA:3.40.50.1220 188 345 2.1E-36 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HRM2_RS14350 571c87b43caa862e2f29b2dca9368f3e 571 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 398 546 7.6E-30 T 22-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HRM2_RS14350 571c87b43caa862e2f29b2dca9368f3e 571 Gene3D G3DSA:3.40.50.970 348 552 2.2E-52 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS14350 571c87b43caa862e2f29b2dca9368f3e 571 PANTHER PTHR18968 3 563 6.5E-141 T 22-04-2016 HRM2_RS14350 571c87b43caa862e2f29b2dca9368f3e 571 SUPERFAMILY SSF52518 375 556 2.95E-47 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS14350 571c87b43caa862e2f29b2dca9368f3e 571 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 436 455 - T 22-04-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 HRM2_RS14350 571c87b43caa862e2f29b2dca9368f3e 571 Gene3D G3DSA:3.40.50.970 2 171 4.8E-56 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS14350 571c87b43caa862e2f29b2dca9368f3e 571 SUPERFAMILY SSF52467 371 391 1.49E-35 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HRM2_RS14350 571c87b43caa862e2f29b2dca9368f3e 571 SUPERFAMILY SSF52467 191 341 1.49E-35 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HRM2_RS14350 571c87b43caa862e2f29b2dca9368f3e 571 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 197 334 3.2E-28 T 22-04-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 HRM2_RS01105 83b0b542826a84560869eccf8be11ee2 260 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 8 212 3.0E-38 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 HRM2_RS01105 83b0b542826a84560869eccf8be11ee2 260 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 8 257 5.8E-94 T 22-04-2016 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 HRM2_RS01105 83b0b542826a84560869eccf8be11ee2 260 SUPERFAMILY SSF53790 3 238 1.44E-61 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 HRM2_RS01105 83b0b542826a84560869eccf8be11ee2 260 PANTHER PTHR21091 1 212 9.1E-54 T 22-04-2016 HRM2_RS01105 83b0b542826a84560869eccf8be11ee2 260 Gene3D G3DSA:3.40.1010.10 6 115 3.1E-30 T 22-04-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 HRM2_RS01105 83b0b542826a84560869eccf8be11ee2 260 Gene3D G3DSA:3.30.950.10 116 235 2.9E-31 T 22-04-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 HRM2_RS01105 83b0b542826a84560869eccf8be11ee2 260 PANTHER PTHR21091:SF17 1 212 9.1E-54 T 22-04-2016 HRM2_RS19085 122dc3c72b614da2ee25691101c8c5f0 325 PANTHER PTHR13707 1 289 7.3E-74 T 22-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 HRM2_RS19085 122dc3c72b614da2ee25691101c8c5f0 325 Gene3D G3DSA:3.30.30.40 123 173 5.7E-26 T 22-04-2016 HRM2_RS19085 122dc3c72b614da2ee25691101c8c5f0 325 Gene3D G3DSA:3.40.1080.10 180 324 2.0E-95 T 22-04-2016 HRM2_RS19085 122dc3c72b614da2ee25691101c8c5f0 325 Gene3D G3DSA:3.40.1080.10 6 122 2.0E-95 T 22-04-2016 HRM2_RS19085 122dc3c72b614da2ee25691101c8c5f0 325 SMART SM00882 8 248 6.8E-27 T 22-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 HRM2_RS19085 122dc3c72b614da2ee25691101c8c5f0 325 SUPERFAMILY SSF100950 6 316 2.44E-77 T 22-04-2016 HRM2_RS19085 122dc3c72b614da2ee25691101c8c5f0 325 PANTHER PTHR13707:SF33 1 289 7.3E-74 T 22-04-2016 HRM2_RS19085 122dc3c72b614da2ee25691101c8c5f0 325 Pfam PF01144 Coenzyme A transferase 8 247 8.9E-33 T 22-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 HRM2_RS05675 45a5616b3cef89d23e9049dd71c7cce6 456 Gene3D G3DSA:3.30.750.44 59 107 2.0E-11 T 22-04-2016 HRM2_RS05675 45a5616b3cef89d23e9049dd71c7cce6 456 Pfam PF13180 PDZ domain 102 179 2.9E-13 T 22-04-2016 IPR001478 PDZ domain GO:0005515 HRM2_RS05675 45a5616b3cef89d23e9049dd71c7cce6 456 SMART SM00245 175 366 3.3E-82 T 22-04-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 HRM2_RS05675 45a5616b3cef89d23e9049dd71c7cce6 456 SUPERFAMILY SSF52096 194 372 1.66E-85 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS05675 45a5616b3cef89d23e9049dd71c7cce6 456 SUPERFAMILY SSF52096 36 120 1.66E-85 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS05675 45a5616b3cef89d23e9049dd71c7cce6 456 Gene3D G3DSA:2.30.42.10 108 183 9.2E-27 T 22-04-2016 IPR001478 PDZ domain GO:0005515 HRM2_RS05675 45a5616b3cef89d23e9049dd71c7cce6 456 Pfam PF03572 Peptidase family S41 201 365 3.0E-56 T 22-04-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 HRM2_RS05675 45a5616b3cef89d23e9049dd71c7cce6 456 SUPERFAMILY SSF50156 96 185 1.44E-21 T 22-04-2016 IPR001478 PDZ domain GO:0005515 HRM2_RS05675 45a5616b3cef89d23e9049dd71c7cce6 456 PANTHER PTHR32060 57 442 5.6E-125 T 22-04-2016 HRM2_RS05675 45a5616b3cef89d23e9049dd71c7cce6 456 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 55 379 1.2E-105 T 22-04-2016 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 HRM2_RS05675 45a5616b3cef89d23e9049dd71c7cce6 456 Gene3D G3DSA:3.90.226.10 184 368 2.4E-68 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS05675 45a5616b3cef89d23e9049dd71c7cce6 456 Gene3D G3DSA:3.90.226.10 421 439 2.4E-68 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS05675 45a5616b3cef89d23e9049dd71c7cce6 456 SMART SM00228 102 173 2.6E-16 T 22-04-2016 IPR001478 PDZ domain GO:0005515 HRM2_RS22860 e47a2ebb965ad64b3efc230b59734eba 499 SUPERFAMILY SSF52540 4 227 7.87E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22860 e47a2ebb965ad64b3efc230b59734eba 499 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS22860 e47a2ebb965ad64b3efc230b59734eba 499 Gene3D G3DSA:3.40.50.300 2 228 1.6E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22860 e47a2ebb965ad64b3efc230b59734eba 499 Gene3D G3DSA:3.40.50.300 255 490 9.8E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22860 e47a2ebb965ad64b3efc230b59734eba 499 ProSitePatterns PS00211 ABC transporters family signature. 402 416 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS22860 e47a2ebb965ad64b3efc230b59734eba 499 Pfam PF00005 ABC transporter 22 170 2.2E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS22860 e47a2ebb965ad64b3efc230b59734eba 499 Pfam PF00005 ABC transporter 274 429 4.8E-14 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS22860 e47a2ebb965ad64b3efc230b59734eba 499 SMART SM00382 282 480 2.2 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS22860 e47a2ebb965ad64b3efc230b59734eba 499 SMART SM00382 30 218 4.2E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS22860 e47a2ebb965ad64b3efc230b59734eba 499 PANTHER PTHR24220:SF239 7 382 7.8E-150 T 22-04-2016 HRM2_RS22860 e47a2ebb965ad64b3efc230b59734eba 499 PANTHER PTHR24220 7 382 7.8E-150 T 22-04-2016 HRM2_RS22860 e47a2ebb965ad64b3efc230b59734eba 499 SUPERFAMILY SSF52540 258 488 1.09E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22780 153b6f863d65f0749b07e92121fb2180 307 SUPERFAMILY SSF89550 5 89 1.04E-37 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 HRM2_RS22780 153b6f863d65f0749b07e92121fb2180 307 SUPERFAMILY SSF89550 181 281 1.04E-37 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 HRM2_RS22780 153b6f863d65f0749b07e92121fb2180 307 Pfam PF02811 PHP domain 8 149 9.0E-11 T 22-04-2016 IPR004013 PHP domain GO:0003824 HRM2_RS22780 153b6f863d65f0749b07e92121fb2180 307 PANTHER PTHR30007:SF4 6 277 6.4E-30 T 22-04-2016 HRM2_RS22780 153b6f863d65f0749b07e92121fb2180 307 SMART SM00481 7 72 1.7E-16 T 22-04-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 HRM2_RS22780 153b6f863d65f0749b07e92121fb2180 307 PANTHER PTHR30007 6 277 6.4E-30 T 22-04-2016 HRM2_RS22780 153b6f863d65f0749b07e92121fb2180 307 Gene3D G3DSA:3.20.20.140 7 94 3.6E-35 T 22-04-2016 HRM2_RS22780 153b6f863d65f0749b07e92121fb2180 307 Gene3D G3DSA:3.20.20.140 174 279 3.6E-35 T 22-04-2016 HRM2_RS20335 f1e85fc16c6a78b642364f9911959a3a 151 Gene3D G3DSA:3.30.565.10 30 89 7.3E-7 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS20335 f1e85fc16c6a78b642364f9911959a3a 151 PANTHER PTHR24567 41 124 2.2E-12 T 22-04-2016 HRM2_RS20335 f1e85fc16c6a78b642364f9911959a3a 151 PANTHER PTHR24567:SF30 41 124 2.2E-12 T 22-04-2016 HRM2_RS20335 f1e85fc16c6a78b642364f9911959a3a 151 SUPERFAMILY SSF55874 31 126 1.02E-7 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS20335 f1e85fc16c6a78b642364f9911959a3a 151 Pfam PF13581 Histidine kinase-like ATPase domain 12 134 1.3E-20 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS01650 7a486a1cefd855bcae7bab43450dc539 544 Gene3D G3DSA:3.40.50.980 23 211 8.7E-36 T 22-04-2016 HRM2_RS01650 7a486a1cefd855bcae7bab43450dc539 544 Pfam PF13193 AMP-binding enzyme C-terminal domain 463 538 2.2E-17 T 22-04-2016 IPR025110 AMP-binding enzyme C-terminal domain HRM2_RS01650 7a486a1cefd855bcae7bab43450dc539 544 PANTHER PTHR24096 177 544 5.5E-147 T 22-04-2016 HRM2_RS01650 7a486a1cefd855bcae7bab43450dc539 544 PANTHER PTHR24096 16 151 5.5E-147 T 22-04-2016 HRM2_RS01650 7a486a1cefd855bcae7bab43450dc539 544 Gene3D G3DSA:3.40.50.980 212 370 8.3E-40 T 22-04-2016 HRM2_RS01650 7a486a1cefd855bcae7bab43450dc539 544 Gene3D G3DSA:3.30.300.30 451 544 2.5E-27 T 22-04-2016 HRM2_RS01650 7a486a1cefd855bcae7bab43450dc539 544 Gene3D G3DSA:2.30.38.10 371 448 1.0E-22 T 22-04-2016 HRM2_RS01650 7a486a1cefd855bcae7bab43450dc539 544 Pfam PF00501 AMP-binding enzyme 29 454 9.9E-96 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS01650 7a486a1cefd855bcae7bab43450dc539 544 SUPERFAMILY SSF56801 18 544 4.97E-142 T 22-04-2016 HRM2_RS01175 2e3a0b3c00414c60ff75806610eded6d 233 PANTHER PTHR26402 4 230 1.3E-86 T 22-04-2016 HRM2_RS01175 2e3a0b3c00414c60ff75806610eded6d 233 Gene3D G3DSA:3.40.50.2300 3 129 2.8E-44 T 22-04-2016 HRM2_RS01175 2e3a0b3c00414c60ff75806610eded6d 233 SMART SM00862 154 227 5.1E-20 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HRM2_RS01175 2e3a0b3c00414c60ff75806610eded6d 233 Pfam PF00072 Response regulator receiver domain 6 118 4.9E-31 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS01175 2e3a0b3c00414c60ff75806610eded6d 233 SUPERFAMILY SSF46894 132 228 8.79E-26 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HRM2_RS01175 2e3a0b3c00414c60ff75806610eded6d 233 SUPERFAMILY SSF52172 2 132 2.56E-45 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS01175 2e3a0b3c00414c60ff75806610eded6d 233 PANTHER PTHR26402:SF614 4 230 1.3E-86 T 22-04-2016 HRM2_RS01175 2e3a0b3c00414c60ff75806610eded6d 233 SMART SM00448 4 117 1.1E-47 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS01175 2e3a0b3c00414c60ff75806610eded6d 233 Gene3D G3DSA:1.10.10.10 133 230 3.7E-29 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS01175 2e3a0b3c00414c60ff75806610eded6d 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 227 5.0E-22 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HRM2_RS23440 02606da5fabb7f81afac348dbc33fddd 519 SUPERFAMILY SSF56317 226 497 2.75E-54 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 HRM2_RS23440 02606da5fabb7f81afac348dbc33fddd 519 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 375 395 - T 22-04-2016 IPR001110 Uncharacterised protein family UPF0012, conserved site HRM2_RS23440 02606da5fabb7f81afac348dbc33fddd 519 PANTHER PTHR23088 212 513 1.3E-133 T 22-04-2016 HRM2_RS23440 02606da5fabb7f81afac348dbc33fddd 519 Gene3D G3DSA:3.40.630.30 14 147 2.4E-16 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS23440 02606da5fabb7f81afac348dbc33fddd 519 Gene3D G3DSA:3.60.110.10 225 511 1.4E-54 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 HRM2_RS23440 02606da5fabb7f81afac348dbc33fddd 519 PANTHER PTHR23088:SF12 212 513 1.3E-133 T 22-04-2016 HRM2_RS23440 02606da5fabb7f81afac348dbc33fddd 519 Pfam PF00583 Acetyltransferase (GNAT) family 90 143 5.8E-5 T 22-04-2016 IPR000182 GNAT domain GO:0008080 HRM2_RS23440 02606da5fabb7f81afac348dbc33fddd 519 SUPERFAMILY SSF55729 10 149 5.49E-16 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS23440 02606da5fabb7f81afac348dbc33fddd 519 Pfam PF00795 Carbon-nitrogen hydrolase 229 491 4.2E-29 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 HRM2_RS21455 a95843be2a11ab58d61b621c08c3e2b8 362 PANTHER PTHR21085 1 358 3.4E-212 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS21455 a95843be2a11ab58d61b621c08c3e2b8 362 Pfam PF01264 Chorismate synthase 9 353 6.2E-141 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS21455 a95843be2a11ab58d61b621c08c3e2b8 362 Hamap MF_00300 Chorismate synthase [aroC]. 9 360 35.586 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS21455 a95843be2a11ab58d61b621c08c3e2b8 362 ProSitePatterns PS00787 Chorismate synthase signature 1. 15 30 - T 22-04-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS21455 a95843be2a11ab58d61b621c08c3e2b8 362 Gene3D G3DSA:3.60.150.10 8 359 3.7E-158 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS21455 a95843be2a11ab58d61b621c08c3e2b8 362 TIGRFAM TIGR00033 aroC: chorismate synthase 9 357 1.2E-141 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS21455 a95843be2a11ab58d61b621c08c3e2b8 362 ProSitePatterns PS00789 Chorismate synthase signature 3. 327 343 - T 22-04-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS21455 a95843be2a11ab58d61b621c08c3e2b8 362 SUPERFAMILY SSF103263 3 358 4.45E-137 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS21455 a95843be2a11ab58d61b621c08c3e2b8 362 PIRSF PIRSF001456 2 362 1.9E-142 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS19450 ac7cead583dabcfac20f43087bc9ace9 430 PANTHER PTHR10799:SF750 238 426 5.4E-30 T 22-04-2016 HRM2_RS19450 ac7cead583dabcfac20f43087bc9ace9 430 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 135 257 5.0E-10 T 22-04-2016 IPR000014 PAS domain HRM2_RS19450 ac7cead583dabcfac20f43087bc9ace9 430 Pfam PF00990 Diguanylate cyclase, GGDEF domain 272 425 1.2E-43 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS19450 ac7cead583dabcfac20f43087bc9ace9 430 SMART SM00267 261 429 2.1E-58 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS19450 ac7cead583dabcfac20f43087bc9ace9 430 SUPERFAMILY SSF55073 277 427 1.1E-46 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS19450 ac7cead583dabcfac20f43087bc9ace9 430 PANTHER PTHR10799 238 426 5.4E-30 T 22-04-2016 HRM2_RS19450 ac7cead583dabcfac20f43087bc9ace9 430 SMART SM00091 135 202 5.3E-8 T 22-04-2016 IPR000014 PAS domain HRM2_RS19450 ac7cead583dabcfac20f43087bc9ace9 430 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 268 428 2.0E-51 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS19450 ac7cead583dabcfac20f43087bc9ace9 430 SUPERFAMILY SSF55785 134 252 1.56E-15 T 22-04-2016 IPR000014 PAS domain HRM2_RS19450 ac7cead583dabcfac20f43087bc9ace9 430 Pfam PF13426 PAS domain 146 252 1.2E-9 T 22-04-2016 IPR000014 PAS domain HRM2_RS19450 ac7cead583dabcfac20f43087bc9ace9 430 Gene3D G3DSA:3.30.70.270 274 427 3.8E-50 T 22-04-2016 HRM2_RS19450 ac7cead583dabcfac20f43087bc9ace9 430 Gene3D G3DSA:3.30.450.20 134 252 1.7E-18 T 22-04-2016 HRM2_RS02590 1af255811bbbac7b5742bca1eb4c56eb 341 PIRSF PIRSF000149 1 338 7.0E-131 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS02590 1af255811bbbac7b5742bca1eb4c56eb 341 PANTHER PTHR10836 1 341 1.8E-199 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS02590 1af255811bbbac7b5742bca1eb4c56eb 341 PANTHER PTHR10836:SF47 1 341 1.8E-199 T 22-04-2016 HRM2_RS02590 1af255811bbbac7b5742bca1eb4c56eb 341 SUPERFAMILY SSF55347 155 318 4.17E-58 T 22-04-2016 HRM2_RS02590 1af255811bbbac7b5742bca1eb4c56eb 341 Gene3D G3DSA:3.30.360.10 164 319 5.1E-61 T 22-04-2016 HRM2_RS02590 1af255811bbbac7b5742bca1eb4c56eb 341 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 112 125 8.9E-31 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS02590 1af255811bbbac7b5742bca1eb4c56eb 341 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 273 288 8.9E-31 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS02590 1af255811bbbac7b5742bca1eb4c56eb 341 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 149 167 8.9E-31 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS02590 1af255811bbbac7b5742bca1eb4c56eb 341 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 233 250 8.9E-31 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS02590 1af255811bbbac7b5742bca1eb4c56eb 341 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 176 192 8.9E-31 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS02590 1af255811bbbac7b5742bca1eb4c56eb 341 SMART SM00846 3 155 1.4E-78 T 22-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS02590 1af255811bbbac7b5742bca1eb4c56eb 341 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 4 155 3.5E-54 T 22-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS02590 1af255811bbbac7b5742bca1eb4c56eb 341 Gene3D G3DSA:3.40.50.720 3 163 7.8E-64 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS02590 1af255811bbbac7b5742bca1eb4c56eb 341 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 329 8.3E-112 T 22-04-2016 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS02590 1af255811bbbac7b5742bca1eb4c56eb 341 SUPERFAMILY SSF51735 1 174 3.49E-56 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS02590 1af255811bbbac7b5742bca1eb4c56eb 341 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 161 316 1.5E-53 T 22-04-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS06570 2c6bad31765c7bcd8690d54d6d71e8e1 332 Pfam PF07478 D-ala D-ala ligase C-terminus 139 319 1.7E-24 T 22-04-2016 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS06570 2c6bad31765c7bcd8690d54d6d71e8e1 332 SUPERFAMILY SSF52440 27 106 4.89E-6 T 22-04-2016 IPR016185 Pre-ATP-grasp domain HRM2_RS06570 2c6bad31765c7bcd8690d54d6d71e8e1 332 PANTHER PTHR23132 51 330 2.1E-50 T 22-04-2016 HRM2_RS06570 2c6bad31765c7bcd8690d54d6d71e8e1 332 SUPERFAMILY SSF56059 109 326 4.28E-36 T 22-04-2016 HRM2_RS06570 2c6bad31765c7bcd8690d54d6d71e8e1 332 Gene3D G3DSA:3.30.470.20 190 328 2.3E-33 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS06570 2c6bad31765c7bcd8690d54d6d71e8e1 332 Gene3D G3DSA:3.30.1490.20 119 189 6.5E-8 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HRM2_RS22025 e914fa6c8b65197eec94e3f4aa1cb72d 531 Pfam PF03050 Transposase IS66 family 181 472 2.6E-94 T 22-04-2016 IPR004291 Transposase, IS66 HRM2_RS22025 e914fa6c8b65197eec94e3f4aa1cb72d 531 Pfam PF13007 Transposase C of IS166 homeodomain 36 108 8.7E-19 T 22-04-2016 IPR024463 Transposase TnpC, homeodomain HRM2_RS22025 e914fa6c8b65197eec94e3f4aa1cb72d 531 Pfam PF13817 IS66 C-terminal element 479 516 1.6E-14 T 22-04-2016 HRM2_RS22025 e914fa6c8b65197eec94e3f4aa1cb72d 531 PANTHER PTHR33678 8 516 9.3E-100 T 22-04-2016 HRM2_RS22025 e914fa6c8b65197eec94e3f4aa1cb72d 531 PANTHER PTHR33678:SF1 8 516 9.3E-100 T 22-04-2016 HRM2_RS22025 e914fa6c8b65197eec94e3f4aa1cb72d 531 Pfam PF13005 zinc-finger binding domain of transposase IS66 117 159 4.8E-13 T 22-04-2016 IPR024474 Zinc-finger binding domain of transposase IS66 HRM2_RS21550 e914fa6c8b65197eec94e3f4aa1cb72d 531 Pfam PF03050 Transposase IS66 family 181 472 2.6E-94 T 22-04-2016 IPR004291 Transposase, IS66 HRM2_RS21550 e914fa6c8b65197eec94e3f4aa1cb72d 531 Pfam PF13007 Transposase C of IS166 homeodomain 36 108 8.7E-19 T 22-04-2016 IPR024463 Transposase TnpC, homeodomain HRM2_RS21550 e914fa6c8b65197eec94e3f4aa1cb72d 531 Pfam PF13817 IS66 C-terminal element 479 516 1.6E-14 T 22-04-2016 HRM2_RS21550 e914fa6c8b65197eec94e3f4aa1cb72d 531 PANTHER PTHR33678 8 516 9.3E-100 T 22-04-2016 HRM2_RS21550 e914fa6c8b65197eec94e3f4aa1cb72d 531 PANTHER PTHR33678:SF1 8 516 9.3E-100 T 22-04-2016 HRM2_RS21550 e914fa6c8b65197eec94e3f4aa1cb72d 531 Pfam PF13005 zinc-finger binding domain of transposase IS66 117 159 4.8E-13 T 22-04-2016 IPR024474 Zinc-finger binding domain of transposase IS66 HRM2_RS01850 e914fa6c8b65197eec94e3f4aa1cb72d 531 Pfam PF03050 Transposase IS66 family 181 472 2.6E-94 T 22-04-2016 IPR004291 Transposase, IS66 HRM2_RS01850 e914fa6c8b65197eec94e3f4aa1cb72d 531 Pfam PF13007 Transposase C of IS166 homeodomain 36 108 8.7E-19 T 22-04-2016 IPR024463 Transposase TnpC, homeodomain HRM2_RS01850 e914fa6c8b65197eec94e3f4aa1cb72d 531 Pfam PF13817 IS66 C-terminal element 479 516 1.6E-14 T 22-04-2016 HRM2_RS01850 e914fa6c8b65197eec94e3f4aa1cb72d 531 PANTHER PTHR33678 8 516 9.3E-100 T 22-04-2016 HRM2_RS01850 e914fa6c8b65197eec94e3f4aa1cb72d 531 PANTHER PTHR33678:SF1 8 516 9.3E-100 T 22-04-2016 HRM2_RS01850 e914fa6c8b65197eec94e3f4aa1cb72d 531 Pfam PF13005 zinc-finger binding domain of transposase IS66 117 159 4.8E-13 T 22-04-2016 IPR024474 Zinc-finger binding domain of transposase IS66 HRM2_RS23475 7db8602d11145f579beef9b87f06df25 568 PANTHER PTHR10909:SF207 1 406 1.7E-176 T 22-04-2016 HRM2_RS23475 7db8602d11145f579beef9b87f06df25 568 Gene3D G3DSA:1.20.140.10 217 387 1.1E-14 T 22-04-2016 HRM2_RS23475 7db8602d11145f579beef9b87f06df25 568 Gene3D G3DSA:2.40.110.10 133 207 1.3E-11 T 22-04-2016 HRM2_RS23475 7db8602d11145f579beef9b87f06df25 568 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 133 204 1.8E-8 T 22-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 HRM2_RS23475 7db8602d11145f579beef9b87f06df25 568 SUPERFAMILY SSF56645 17 207 3.27E-20 T 22-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 HRM2_RS23475 7db8602d11145f579beef9b87f06df25 568 PANTHER PTHR10909 1 406 1.7E-176 T 22-04-2016 HRM2_RS23475 7db8602d11145f579beef9b87f06df25 568 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 238 385 1.3E-10 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS23475 7db8602d11145f579beef9b87f06df25 568 SUPERFAMILY SSF47203 237 393 1.77E-19 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS08805 032eab9ee5c088626edb266279574c11 262 Pfam PF00218 Indole-3-glycerol phosphate synthase 8 261 7.0E-80 T 22-04-2016 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48|UniPathway: UPA00035 HRM2_RS08805 032eab9ee5c088626edb266279574c11 262 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 57 75 - T 22-04-2016 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48|UniPathway: UPA00035 HRM2_RS08805 032eab9ee5c088626edb266279574c11 262 SUPERFAMILY SSF51366 15 261 8.36E-75 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 HRM2_RS08805 032eab9ee5c088626edb266279574c11 262 PANTHER PTHR22854:SF2 1 262 4.0E-85 T 22-04-2016 HRM2_RS08805 032eab9ee5c088626edb266279574c11 262 PANTHER PTHR22854 1 262 4.0E-85 T 22-04-2016 HRM2_RS08805 032eab9ee5c088626edb266279574c11 262 Gene3D G3DSA:3.20.20.70 6 262 9.0E-85 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS00330 51c6e6536cca237a27388621cbf701c2 396 PANTHER PTHR30489 213 396 1.5E-34 T 22-04-2016 HRM2_RS00330 51c6e6536cca237a27388621cbf701c2 396 PANTHER PTHR30489 1 183 1.5E-34 T 22-04-2016 HRM2_RS00330 51c6e6536cca237a27388621cbf701c2 396 Pfam PF02687 FtsX-like permease family 280 390 7.8E-10 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 HRM2_RS00330 51c6e6536cca237a27388621cbf701c2 396 Pfam PF12704 MacB-like periplasmic core domain 18 249 1.9E-12 T 22-04-2016 IPR025857 MacB-like periplasmic core domain HRM2_RS10105 026d64ba0c36b58572f0ecd1dffd0912 476 Gene3D G3DSA:1.10.45.10 424 463 3.0E-9 T 22-04-2016 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 HRM2_RS10105 026d64ba0c36b58572f0ecd1dffd0912 476 Gene3D G3DSA:3.30.43.10 8 98 6.7E-29 T 22-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 HRM2_RS10105 026d64ba0c36b58572f0ecd1dffd0912 476 PANTHER PTHR11748 27 466 6.1E-150 T 22-04-2016 HRM2_RS10105 026d64ba0c36b58572f0ecd1dffd0912 476 PANTHER PTHR11748:SF85 27 466 6.1E-150 T 22-04-2016 HRM2_RS10105 026d64ba0c36b58572f0ecd1dffd0912 476 Pfam PF02913 FAD linked oxidases, C-terminal domain 219 463 4.0E-50 T 22-04-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 HRM2_RS10105 026d64ba0c36b58572f0ecd1dffd0912 476 Gene3D G3DSA:3.30.465.10 99 219 9.5E-41 T 22-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 HRM2_RS10105 026d64ba0c36b58572f0ecd1dffd0912 476 SUPERFAMILY SSF55103 222 466 9.32E-53 T 22-04-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 HRM2_RS10105 026d64ba0c36b58572f0ecd1dffd0912 476 Pfam PF01565 FAD binding domain 43 181 8.6E-42 T 22-04-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 HRM2_RS10105 026d64ba0c36b58572f0ecd1dffd0912 476 SUPERFAMILY SSF56176 8 219 2.85E-72 T 22-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 HRM2_RS00805 849f725101ac74175ed9cb813fc444bc 357 SUPERFAMILY SSF50331 232 350 6.29E-19 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal HRM2_RS00805 849f725101ac74175ed9cb813fc444bc 357 PANTHER PTHR24220:SF421 4 236 4.7E-116 T 22-04-2016 IPR030283 Molybdate/tungstate import ATP-binding protein WtpC GO:0005524|GO:0006810|GO:0015412 KEGG: 00920+3.6.3.- HRM2_RS00805 849f725101ac74175ed9cb813fc444bc 357 PANTHER PTHR24220:SF421 260 288 4.7E-116 T 22-04-2016 IPR030283 Molybdate/tungstate import ATP-binding protein WtpC GO:0005524|GO:0006810|GO:0015412 KEGG: 00920+3.6.3.- HRM2_RS00805 849f725101ac74175ed9cb813fc444bc 357 PANTHER PTHR24220:SF421 347 357 4.7E-116 T 22-04-2016 IPR030283 Molybdate/tungstate import ATP-binding protein WtpC GO:0005524|GO:0006810|GO:0015412 KEGG: 00920+3.6.3.- HRM2_RS00805 849f725101ac74175ed9cb813fc444bc 357 Gene3D G3DSA:3.40.50.300 3 229 5.4E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00805 849f725101ac74175ed9cb813fc444bc 357 SMART SM00382 26 223 6.6E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS00805 849f725101ac74175ed9cb813fc444bc 357 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS00805 849f725101ac74175ed9cb813fc444bc 357 SUPERFAMILY SSF52540 3 232 2.18E-74 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00805 849f725101ac74175ed9cb813fc444bc 357 PANTHER PTHR24220 4 236 4.7E-116 T 22-04-2016 HRM2_RS00805 849f725101ac74175ed9cb813fc444bc 357 PANTHER PTHR24220 260 288 4.7E-116 T 22-04-2016 HRM2_RS00805 849f725101ac74175ed9cb813fc444bc 357 PANTHER PTHR24220 347 357 4.7E-116 T 22-04-2016 HRM2_RS00805 849f725101ac74175ed9cb813fc444bc 357 Pfam PF00005 ABC transporter 17 157 3.4E-32 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS10695 769d3e71200664dbef3ba05b8533cce0 124 SUPERFAMILY SSF82649 6 120 8.37E-29 T 22-04-2016 HRM2_RS10695 769d3e71200664dbef3ba05b8533cce0 124 Pfam PF01592 NifU-like N terminal domain 7 118 1.2E-23 T 22-04-2016 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 HRM2_RS10695 769d3e71200664dbef3ba05b8533cce0 124 PANTHER PTHR10093 7 117 2.8E-21 T 22-04-2016 HRM2_RS10695 769d3e71200664dbef3ba05b8533cce0 124 Gene3D G3DSA:3.90.1010.10 7 120 9.8E-27 T 22-04-2016 HRM2_RS24890 16d4f4033b057405208cb1a740ab52dd 569 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 427 456 1.6E-6 T 22-04-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HRM2_RS24890 16d4f4033b057405208cb1a740ab52dd 569 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 475 504 1.6E-6 T 22-04-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HRM2_RS24890 16d4f4033b057405208cb1a740ab52dd 569 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 328 357 1.6E-6 T 22-04-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HRM2_RS24890 16d4f4033b057405208cb1a740ab52dd 569 SMART SM00283 307 568 4.7E-36 T 22-04-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HRM2_RS24890 16d4f4033b057405208cb1a740ab52dd 569 PANTHER PTHR32089 128 569 5.6E-79 T 22-04-2016 HRM2_RS24890 16d4f4033b057405208cb1a740ab52dd 569 SMART SM00304 226 278 6.9E-8 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS24890 16d4f4033b057405208cb1a740ab52dd 569 SUPERFAMILY SSF58104 246 540 2.62E-53 T 22-04-2016 HRM2_RS24890 16d4f4033b057405208cb1a740ab52dd 569 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 368 567 2.0E-33 T 22-04-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HRM2_RS24890 16d4f4033b057405208cb1a740ab52dd 569 Gene3D G3DSA:1.10.287.950 322 523 2.4E-41 T 22-04-2016 HRM2_RS24890 16d4f4033b057405208cb1a740ab52dd 569 Pfam PF00672 HAMP domain 207 273 3.2E-12 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS19040 1b4a6a52a57988db27392ccc245b3ec0 510 Gene3D G3DSA:3.40.605.10 21 276 7.5E-70 T 22-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 HRM2_RS19040 1b4a6a52a57988db27392ccc245b3ec0 510 SUPERFAMILY SSF53720 21 498 1.03E-127 T 22-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 HRM2_RS19040 1b4a6a52a57988db27392ccc245b3ec0 510 PANTHER PTHR11699 1 509 2.0E-265 T 22-04-2016 HRM2_RS19040 1b4a6a52a57988db27392ccc245b3ec0 510 PANTHER PTHR11699:SF144 1 509 2.0E-265 T 22-04-2016 HRM2_RS19040 1b4a6a52a57988db27392ccc245b3ec0 510 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 261 268 - T 22-04-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 HRM2_RS19040 1b4a6a52a57988db27392ccc245b3ec0 510 Pfam PF00171 Aldehyde dehydrogenase family 25 491 5.4E-130 T 22-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 HRM2_RS19040 1b4a6a52a57988db27392ccc245b3ec0 510 Gene3D G3DSA:3.40.309.10 277 457 2.6E-49 T 22-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 HRM2_RS15200 25fb71d0c5f52785e62be28316026e10 224 PANTHER PTHR38755 1 215 2.1E-19 T 22-04-2016 HRM2_RS15200 25fb71d0c5f52785e62be28316026e10 224 PANTHER PTHR38755:SF1 1 215 2.1E-19 T 22-04-2016 HRM2_RS15200 25fb71d0c5f52785e62be28316026e10 224 Pfam PF12225 Methylene-tetrahydrofolate reductase C terminal 109 203 3.0E-36 T 22-04-2016 IPR022026 Methylene-tetrahydrofolate reductase C-terminal HRM2_RS14670 0db18abd855eacdd2856117d10a7f417 923 Pfam PF00012 Hsp70 protein 132 340 5.5E-16 T 22-04-2016 IPR013126 Heat shock protein 70 family HRM2_RS14670 0db18abd855eacdd2856117d10a7f417 923 SUPERFAMILY SSF53067 8 209 1.2E-27 T 22-04-2016 HRM2_RS14670 0db18abd855eacdd2856117d10a7f417 923 PANTHER PTHR19375 49 326 9.3E-44 T 22-04-2016 HRM2_RS14670 0db18abd855eacdd2856117d10a7f417 923 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 12 19 - T 22-04-2016 IPR018181 Heat shock protein 70, conserved site HRM2_RS14670 0db18abd855eacdd2856117d10a7f417 923 Gene3D G3DSA:3.30.420.40 229 303 3.1E-10 T 22-04-2016 HRM2_RS14670 0db18abd855eacdd2856117d10a7f417 923 Gene3D G3DSA:3.30.420.40 373 423 3.1E-10 T 22-04-2016 HRM2_RS14670 0db18abd855eacdd2856117d10a7f417 923 PANTHER PTHR19375:SF226 8 25 9.3E-44 T 22-04-2016 HRM2_RS14670 0db18abd855eacdd2856117d10a7f417 923 PANTHER PTHR19375:SF226 49 326 9.3E-44 T 22-04-2016 HRM2_RS14670 0db18abd855eacdd2856117d10a7f417 923 Pfam PF12531 DNA-K related protein 680 922 3.1E-84 T 22-04-2016 IPR021030 Protein of unknown function DUF3731 HRM2_RS14670 0db18abd855eacdd2856117d10a7f417 923 PRINTS PR00301 70kDa heat shock protein signature 165 185 1.3E-7 T 22-04-2016 IPR013126 Heat shock protein 70 family HRM2_RS14670 0db18abd855eacdd2856117d10a7f417 923 PRINTS PR00301 70kDa heat shock protein signature 233 243 1.3E-7 T 22-04-2016 IPR013126 Heat shock protein 70 family HRM2_RS14670 0db18abd855eacdd2856117d10a7f417 923 PRINTS PR00301 70kDa heat shock protein signature 8 21 1.3E-7 T 22-04-2016 IPR013126 Heat shock protein 70 family HRM2_RS14670 0db18abd855eacdd2856117d10a7f417 923 PANTHER PTHR19375 8 25 9.3E-44 T 22-04-2016 HRM2_RS14670 0db18abd855eacdd2856117d10a7f417 923 SUPERFAMILY SSF53067 399 457 1.18E-25 T 22-04-2016 HRM2_RS14670 0db18abd855eacdd2856117d10a7f417 923 SUPERFAMILY SSF53067 222 370 1.18E-25 T 22-04-2016 HRM2_RS14670 0db18abd855eacdd2856117d10a7f417 923 Gene3D G3DSA:3.30.420.40 8 228 1.5E-32 T 22-04-2016 HRM2_RS15325 38a282e6b81810d080f707ca92d86913 333 Gene3D G3DSA:3.40.50.620 4 189 1.4E-22 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS15325 38a282e6b81810d080f707ca92d86913 333 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 11 147 1.2E-4 T 22-04-2016 IPR020536 Thil, AANH domain GO:0004810 UniPathway: UPA00060 HRM2_RS15325 38a282e6b81810d080f707ca92d86913 333 PANTHER PTHR11933:SF6 7 292 3.3E-93 T 22-04-2016 HRM2_RS15325 38a282e6b81810d080f707ca92d86913 333 PANTHER PTHR11933 7 292 3.3E-93 T 22-04-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 HRM2_RS15325 38a282e6b81810d080f707ca92d86913 333 Pfam PF05670 Domain of unknown function (DUF814) 236 312 8.0E-7 T 22-04-2016 IPR008532 Domain of unknown function DUF814 HRM2_RS15325 38a282e6b81810d080f707ca92d86913 333 SUPERFAMILY SSF52402 11 234 8.38E-28 T 22-04-2016 HRM2_RS14700 92b52430099621b94089dbc0ba94cc78 643 SUPERFAMILY SSF51735 304 569 3.12E-57 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS14700 92b52430099621b94089dbc0ba94cc78 643 Pfam PF13727 CoA-binding domain 65 261 9.5E-15 T 22-04-2016 HRM2_RS14700 92b52430099621b94089dbc0ba94cc78 643 PANTHER PTHR10366:SF256 305 575 9.8E-115 T 22-04-2016 HRM2_RS14700 92b52430099621b94089dbc0ba94cc78 643 PANTHER PTHR10366 305 575 9.8E-115 T 22-04-2016 HRM2_RS14700 92b52430099621b94089dbc0ba94cc78 643 Pfam PF02719 Polysaccharide biosynthesis protein 306 590 5.3E-120 T 22-04-2016 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain HRM2_RS14700 92b52430099621b94089dbc0ba94cc78 643 Gene3D G3DSA:3.40.50.720 305 487 1.7E-45 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS14700 92b52430099621b94089dbc0ba94cc78 643 Gene3D G3DSA:3.90.25.10 488 567 1.8E-6 T 22-04-2016 HRM2_RS14700 92b52430099621b94089dbc0ba94cc78 643 Gene3D G3DSA:3.40.50.720 158 271 1.1E-15 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS14700 92b52430099621b94089dbc0ba94cc78 643 SUPERFAMILY SSF51735 164 293 3.78E-19 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS05775 e149f75cba020b26545a34d237214477 481 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 54 79 - T 22-04-2016 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 HRM2_RS05775 e149f75cba020b26545a34d237214477 481 PANTHER PTHR11993 305 481 2.2E-107 T 22-04-2016 HRM2_RS05775 e149f75cba020b26545a34d237214477 481 PANTHER PTHR11993 158 219 2.2E-107 T 22-04-2016 HRM2_RS05775 e149f75cba020b26545a34d237214477 481 PANTHER PTHR11993 18 131 2.2E-107 T 22-04-2016 HRM2_RS05775 e149f75cba020b26545a34d237214477 481 Gene3D G3DSA:1.10.645.10 16 481 3.8E-161 T 22-04-2016 IPR029014 NiFe hydrogenase-like HRM2_RS05775 e149f75cba020b26545a34d237214477 481 SUPERFAMILY SSF56762 18 481 6.54E-140 T 22-04-2016 IPR029014 NiFe hydrogenase-like HRM2_RS05775 e149f75cba020b26545a34d237214477 481 PANTHER PTHR11993:SF11 305 481 2.2E-107 T 22-04-2016 HRM2_RS05775 e149f75cba020b26545a34d237214477 481 PANTHER PTHR11993:SF11 158 219 2.2E-107 T 22-04-2016 HRM2_RS05775 e149f75cba020b26545a34d237214477 481 PANTHER PTHR11993:SF11 18 131 2.2E-107 T 22-04-2016 HRM2_RS05775 e149f75cba020b26545a34d237214477 481 Pfam PF00374 Nickel-dependent hydrogenase 136 481 2.6E-86 T 22-04-2016 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 HRM2_RS05775 e149f75cba020b26545a34d237214477 481 Pfam PF00374 Nickel-dependent hydrogenase 54 133 7.7E-35 T 22-04-2016 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 HRM2_RS06995 12411fc37c9d928f793366c381e829ea 273 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 33 251 1.2E-42 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS06995 12411fc37c9d928f793366c381e829ea 273 Gene3D G3DSA:3.40.190.10 120 202 1.8E-15 T 22-04-2016 HRM2_RS06995 12411fc37c9d928f793366c381e829ea 273 SMART SM00062 31 254 1.0E-35 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS06995 12411fc37c9d928f793366c381e829ea 273 PANTHER PTHR18966 35 252 1.6E-18 T 22-04-2016 HRM2_RS06995 12411fc37c9d928f793366c381e829ea 273 Gene3D G3DSA:3.40.190.10 31 116 6.9E-28 T 22-04-2016 HRM2_RS06995 12411fc37c9d928f793366c381e829ea 273 Gene3D G3DSA:3.40.190.10 212 252 6.9E-28 T 22-04-2016 HRM2_RS06995 12411fc37c9d928f793366c381e829ea 273 SUPERFAMILY SSF53850 11 252 8.15E-51 T 22-04-2016 HRM2_RS22590 6a307486ceb93eb45eb0c3598ad5d954 255 SUPERFAMILY SSF53800 4 250 3.14E-58 T 22-04-2016 HRM2_RS22590 6a307486ceb93eb45eb0c3598ad5d954 255 Pfam PF06180 Cobalt chelatase (CbiK) 6 250 1.1E-52 T 22-04-2016 IPR010388 Anaerobic cobalt chelatase GO:0016852|GO:0019251 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 HRM2_RS22590 6a307486ceb93eb45eb0c3598ad5d954 255 PIRSF PIRSF033579 1 253 1.5E-57 T 22-04-2016 IPR010388 Anaerobic cobalt chelatase GO:0016852|GO:0019251 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 HRM2_RS22590 6a307486ceb93eb45eb0c3598ad5d954 255 Gene3D G3DSA:3.40.50.1400 5 146 3.4E-26 T 22-04-2016 HRM2_RS22590 6a307486ceb93eb45eb0c3598ad5d954 255 Gene3D G3DSA:3.40.50.1400 170 234 4.6E-14 T 22-04-2016 HRM2_RS06825 5fec0000ccc83486e23d8fb7a73b63ba 576 PANTHER PTHR23406:SF2 19 576 3.1E-210 T 22-04-2016 HRM2_RS06825 5fec0000ccc83486e23d8fb7a73b63ba 576 SUPERFAMILY SSF51735 279 574 1.67E-78 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS06825 5fec0000ccc83486e23d8fb7a73b63ba 576 SMART SM00919 279 537 1.2E-95 T 22-04-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 HRM2_RS06825 5fec0000ccc83486e23d8fb7a73b63ba 576 SUPERFAMILY SSF53223 7 278 1.01E-84 T 22-04-2016 HRM2_RS06825 5fec0000ccc83486e23d8fb7a73b63ba 576 Gene3D G3DSA:3.40.50.10380 24 276 7.1E-84 T 22-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 HRM2_RS06825 5fec0000ccc83486e23d8fb7a73b63ba 576 PIRSF PIRSF000106 3 576 5.1E-198 T 22-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 HRM2_RS06825 5fec0000ccc83486e23d8fb7a73b63ba 576 PANTHER PTHR23406 19 576 3.1E-210 T 22-04-2016 HRM2_RS06825 5fec0000ccc83486e23d8fb7a73b63ba 576 ProSitePatterns PS00331 Malic enzymes signature. 275 291 - T 22-04-2016 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 HRM2_RS06825 5fec0000ccc83486e23d8fb7a73b63ba 576 Pfam PF00390 Malic enzyme, N-terminal domain 90 268 8.3E-60 T 22-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 HRM2_RS06825 5fec0000ccc83486e23d8fb7a73b63ba 576 Gene3D G3DSA:3.40.50.720 277 574 3.8E-92 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS06825 5fec0000ccc83486e23d8fb7a73b63ba 576 SMART SM01274 89 269 1.1E-75 T 22-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 HRM2_RS06825 5fec0000ccc83486e23d8fb7a73b63ba 576 PRINTS PR00072 Malic enzyme signature 250 268 5.5E-63 T 22-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 HRM2_RS06825 5fec0000ccc83486e23d8fb7a73b63ba 576 PRINTS PR00072 Malic enzyme signature 414 430 5.5E-63 T 22-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 HRM2_RS06825 5fec0000ccc83486e23d8fb7a73b63ba 576 PRINTS PR00072 Malic enzyme signature 95 119 5.5E-63 T 22-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 HRM2_RS06825 5fec0000ccc83486e23d8fb7a73b63ba 576 PRINTS PR00072 Malic enzyme signature 191 213 5.5E-63 T 22-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 HRM2_RS06825 5fec0000ccc83486e23d8fb7a73b63ba 576 PRINTS PR00072 Malic enzyme signature 275 291 5.5E-63 T 22-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 HRM2_RS06825 5fec0000ccc83486e23d8fb7a73b63ba 576 PRINTS PR00072 Malic enzyme signature 306 322 5.5E-63 T 22-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 HRM2_RS06825 5fec0000ccc83486e23d8fb7a73b63ba 576 PRINTS PR00072 Malic enzyme signature 155 184 5.5E-63 T 22-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 HRM2_RS06825 5fec0000ccc83486e23d8fb7a73b63ba 576 Pfam PF03949 Malic enzyme, NAD binding domain 279 533 6.0E-88 T 22-04-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 HRM2_RS02405 9ec5e98fcd46f9d33f65360e8aa20dbe 189 SUPERFAMILY SSF55811 13 174 2.41E-25 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HRM2_RS02405 9ec5e98fcd46f9d33f65360e8aa20dbe 189 Gene3D G3DSA:3.90.79.10 15 172 6.5E-30 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HRM2_RS02405 9ec5e98fcd46f9d33f65360e8aa20dbe 189 Pfam PF00293 NUDIX domain 26 129 4.1E-11 T 22-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 HRM2_RS02405 9ec5e98fcd46f9d33f65360e8aa20dbe 189 PANTHER PTHR12992 17 172 1.5E-26 T 22-04-2016 HRM2_RS05350 c7fe7fde677faf80e982f5933c19aac8 520 Gene3D G3DSA:3.20.20.140 159 280 1.1E-33 T 22-04-2016 HRM2_RS05350 c7fe7fde677faf80e982f5933c19aac8 520 Gene3D G3DSA:3.20.20.140 2 90 1.1E-33 T 22-04-2016 HRM2_RS05350 c7fe7fde677faf80e982f5933c19aac8 520 Pfam PF02811 PHP domain 3 175 2.6E-9 T 22-04-2016 IPR004013 PHP domain GO:0003824 HRM2_RS05350 c7fe7fde677faf80e982f5933c19aac8 520 Hamap MF_00104 Ribonuclease 3 [rnc]. 296 512 28.82 T 22-04-2016 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 HRM2_RS05350 c7fe7fde677faf80e982f5933c19aac8 520 SMART SM00358 450 516 4.3E-19 T 22-04-2016 IPR014720 Double-stranded RNA-binding domain HRM2_RS05350 c7fe7fde677faf80e982f5933c19aac8 520 Pfam PF14622 Ribonuclease-III-like 306 437 3.2E-34 T 22-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 HRM2_RS05350 c7fe7fde677faf80e982f5933c19aac8 520 PANTHER PTHR11207 288 518 1.2E-68 T 22-04-2016 HRM2_RS05350 c7fe7fde677faf80e982f5933c19aac8 520 SUPERFAMILY SSF54768 403 517 2.04E-26 T 22-04-2016 HRM2_RS05350 c7fe7fde677faf80e982f5933c19aac8 520 Pfam PF00035 Double-stranded RNA binding motif 451 515 7.2E-14 T 22-04-2016 IPR014720 Double-stranded RNA-binding domain HRM2_RS05350 c7fe7fde677faf80e982f5933c19aac8 520 SMART SM00481 2 67 2.9E-12 T 22-04-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 HRM2_RS05350 c7fe7fde677faf80e982f5933c19aac8 520 SMART SM00535 308 443 9.9E-47 T 22-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 HRM2_RS05350 c7fe7fde677faf80e982f5933c19aac8 520 Gene3D G3DSA:1.10.1520.10 293 438 8.8E-43 T 22-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 HRM2_RS05350 c7fe7fde677faf80e982f5933c19aac8 520 SUPERFAMILY SSF69065 290 438 5.58E-44 T 22-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 HRM2_RS05350 c7fe7fde677faf80e982f5933c19aac8 520 SUPERFAMILY SSF89550 2 85 1.57E-39 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 HRM2_RS05350 c7fe7fde677faf80e982f5933c19aac8 520 SUPERFAMILY SSF89550 167 265 1.57E-39 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 HRM2_RS05350 c7fe7fde677faf80e982f5933c19aac8 520 Gene3D G3DSA:3.30.160.20 448 516 9.7E-22 T 22-04-2016 IPR014720 Double-stranded RNA-binding domain HRM2_RS05350 c7fe7fde677faf80e982f5933c19aac8 520 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 296 515 2.8E-71 T 22-04-2016 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 HRM2_RS15540 cec6a4c83ebe1fefa8eaa1ff37474447 537 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 226 285 3.3E-7 T 22-04-2016 HRM2_RS15540 cec6a4c83ebe1fefa8eaa1ff37474447 537 Gene3D G3DSA:2.130.10.130 208 513 3.5E-6 T 22-04-2016 HRM2_RS15540 cec6a4c83ebe1fefa8eaa1ff37474447 537 SUPERFAMILY SSF69318 209 514 5.14E-15 T 22-04-2016 HRM2_RS20055 d9c33ec4d278d296339a12afb24a9197 284 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 5 269 28.089 T 22-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 HRM2_RS20055 d9c33ec4d278d296339a12afb24a9197 284 SUPERFAMILY SSF51735 6 161 3.47E-31 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS20055 d9c33ec4d278d296339a12afb24a9197 284 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 6 101 1.0E-19 T 22-04-2016 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal HRM2_RS20055 d9c33ec4d278d296339a12afb24a9197 284 Gene3D G3DSA:3.40.50.720 3 161 4.0E-46 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS20055 d9c33ec4d278d296339a12afb24a9197 284 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 7 269 4.5E-85 T 22-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 HRM2_RS20055 d9c33ec4d278d296339a12afb24a9197 284 PIRSF PIRSF000193 4 271 1.0E-82 T 22-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 HRM2_RS20055 d9c33ec4d278d296339a12afb24a9197 284 PANTHER PTHR11645:SF28 2 282 6.8E-118 T 22-04-2016 HRM2_RS20055 d9c33ec4d278d296339a12afb24a9197 284 PANTHER PTHR11645 2 282 6.8E-118 T 22-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 HRM2_RS20055 d9c33ec4d278d296339a12afb24a9197 284 Gene3D G3DSA:1.10.3730.10 167 269 9.6E-44 T 22-04-2016 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 HRM2_RS20055 d9c33ec4d278d296339a12afb24a9197 284 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 167 269 5.6E-40 T 22-04-2016 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 HRM2_RS20055 d9c33ec4d278d296339a12afb24a9197 284 SUPERFAMILY SSF48179 167 271 5.78E-37 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HRM2_RS05935 38302faeae277c6ab6fe19c2da587d2c 344 PANTHER PTHR11728 10 339 3.1E-130 T 22-04-2016 HRM2_RS05935 38302faeae277c6ab6fe19c2da587d2c 344 Gene3D G3DSA:3.40.50.720 4 195 3.4E-55 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS05935 38302faeae277c6ab6fe19c2da587d2c 344 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 11 167 3.7E-45 T 22-04-2016 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 HRM2_RS05935 38302faeae277c6ab6fe19c2da587d2c 344 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 196 217 - T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 HRM2_RS05935 38302faeae277c6ab6fe19c2da587d2c 344 SUPERFAMILY SSF51735 10 186 5.05E-49 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS05935 38302faeae277c6ab6fe19c2da587d2c 344 Gene3D G3DSA:1.10.1040.10 197 340 9.0E-56 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HRM2_RS05935 38302faeae277c6ab6fe19c2da587d2c 344 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 9 330 35.726 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 HRM2_RS05935 38302faeae277c6ab6fe19c2da587d2c 344 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 188 328 2.8E-51 T 22-04-2016 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 HRM2_RS05935 38302faeae277c6ab6fe19c2da587d2c 344 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 13 30 2.1E-46 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 HRM2_RS05935 38302faeae277c6ab6fe19c2da587d2c 344 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 181 205 2.1E-46 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 HRM2_RS05935 38302faeae277c6ab6fe19c2da587d2c 344 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 246 263 2.1E-46 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 HRM2_RS05935 38302faeae277c6ab6fe19c2da587d2c 344 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 141 161 2.1E-46 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 HRM2_RS05935 38302faeae277c6ab6fe19c2da587d2c 344 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 206 230 2.1E-46 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 HRM2_RS05935 38302faeae277c6ab6fe19c2da587d2c 344 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 63 90 2.1E-46 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 HRM2_RS05935 38302faeae277c6ab6fe19c2da587d2c 344 PIRSF PIRSF000114 3 340 3.2E-105 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 HRM2_RS05935 38302faeae277c6ab6fe19c2da587d2c 344 SUPERFAMILY SSF48179 187 339 2.72E-55 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HRM2_RS15230 ba5a3f5caa1d6294315e005d3892f925 309 SUPERFAMILY SSF51730 8 305 4.71E-70 T 22-04-2016 IPR029041 FAD-linked oxidoreductase-like HRM2_RS15230 ba5a3f5caa1d6294315e005d3892f925 309 Gene3D G3DSA:3.20.20.220 7 306 5.4E-58 T 22-04-2016 IPR029041 FAD-linked oxidoreductase-like HRM2_RS15230 ba5a3f5caa1d6294315e005d3892f925 309 Pfam PF02219 Methylenetetrahydrofolate reductase 9 302 8.1E-37 T 22-04-2016 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 HRM2_RS04635 05b5f65ea439844246cac13b659256a3 184 Gene3D G3DSA:1.10.3290.10 9 97 1.1E-11 T 22-04-2016 IPR003812 Fido domain HRM2_RS04635 05b5f65ea439844246cac13b659256a3 184 SUPERFAMILY SSF140931 10 98 9.02E-11 T 22-04-2016 IPR003812 Fido domain HRM2_RS02210 8ea2fc7c0f4c55db31c04f56e679aea7 391 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 28 39 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS02210 8ea2fc7c0f4c55db31c04f56e679aea7 391 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 72 83 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS02210 8ea2fc7c0f4c55db31c04f56e679aea7 391 Gene3D G3DSA:1.20.950.20 179 204 9.0E-14 T 22-04-2016 HRM2_RS02210 8ea2fc7c0f4c55db31c04f56e679aea7 391 Gene3D G3DSA:1.20.950.20 236 376 9.0E-14 T 22-04-2016 HRM2_RS02210 8ea2fc7c0f4c55db31c04f56e679aea7 391 Pfam PF13534 4Fe-4S dicluster domain 27 85 4.5E-8 T 22-04-2016 HRM2_RS02210 8ea2fc7c0f4c55db31c04f56e679aea7 391 SUPERFAMILY SSF103501 235 387 8.89E-24 T 22-04-2016 IPR023234 NarG-like domain HRM2_RS02210 8ea2fc7c0f4c55db31c04f56e679aea7 391 SUPERFAMILY SSF103501 177 204 8.89E-24 T 22-04-2016 IPR023234 NarG-like domain HRM2_RS02210 8ea2fc7c0f4c55db31c04f56e679aea7 391 Gene3D G3DSA:1.10.1060.10 12 106 1.0E-13 T 22-04-2016 HRM2_RS02210 8ea2fc7c0f4c55db31c04f56e679aea7 391 SUPERFAMILY SSF46548 9 100 1.48E-15 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS00365 5f653eec62527ae76a3bfa13baeaf415 713 TIGRFAM TIGR04344 ovoA_Nterm: 5-histidylcysteine sulfoxide synthase 10 448 1.3E-210 T 22-04-2016 IPR027577 5-histidylcysteine sulfoxide synthase HRM2_RS00365 5f653eec62527ae76a3bfa13baeaf415 713 TIGRFAM TIGR04345 ovoA_Cterm: putative 4-mercaptohistidine N1-methyltranferase 461 702 2.0E-105 T 22-04-2016 IPR027625 Putative 4-mercaptohistidine N1-methyltranferase, OvoA C-terminal domain HRM2_RS00365 5f653eec62527ae76a3bfa13baeaf415 713 SUPERFAMILY SSF53335 464 669 1.82E-21 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS00365 5f653eec62527ae76a3bfa13baeaf415 713 PANTHER PTHR23150 2 485 2.9E-192 T 22-04-2016 HRM2_RS00365 5f653eec62527ae76a3bfa13baeaf415 713 Pfam PF13847 Methyltransferase domain 502 638 4.7E-13 T 22-04-2016 IPR025714 Methyltransferase domain HRM2_RS00365 5f653eec62527ae76a3bfa13baeaf415 713 SUPERFAMILY SSF56436 193 450 1.32E-56 T 22-04-2016 IPR016187 C-type lectin fold HRM2_RS00365 5f653eec62527ae76a3bfa13baeaf415 713 Pfam PF03781 Sulfatase-modifying factor enzyme 1 195 448 2.0E-30 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme HRM2_RS00365 5f653eec62527ae76a3bfa13baeaf415 713 Pfam PF12867 DinB superfamily 34 164 2.6E-6 T 22-04-2016 IPR024775 DinB-like domain HRM2_RS00365 5f653eec62527ae76a3bfa13baeaf415 713 Gene3D G3DSA:3.40.50.150 473 663 1.7E-23 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS00365 5f653eec62527ae76a3bfa13baeaf415 713 Gene3D G3DSA:3.90.1580.10 186 454 1.4E-52 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme HRM2_RS00365 5f653eec62527ae76a3bfa13baeaf415 713 PANTHER PTHR23150:SF24 2 485 2.9E-192 T 22-04-2016 HRM2_RS17820 26aade8c4aec5b6551c517eee917eb36 164 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 11 159 1.2E-63 T 22-04-2016 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 HRM2_RS17820 26aade8c4aec5b6551c517eee917eb36 164 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 157 8.7E-30 T 22-04-2016 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 HRM2_RS17820 26aade8c4aec5b6551c517eee917eb36 164 PANTHER PTHR13718 11 159 6.8E-64 T 22-04-2016 IPR000851 Ribosomal protein S5 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17820 26aade8c4aec5b6551c517eee917eb36 164 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 163 33.928 T 22-04-2016 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 HRM2_RS17820 26aade8c4aec5b6551c517eee917eb36 164 Pfam PF00333 Ribosomal protein S5, N-terminal domain 11 74 6.2E-29 T 22-04-2016 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 HRM2_RS17820 26aade8c4aec5b6551c517eee917eb36 164 Gene3D G3DSA:3.30.160.20 11 72 6.5E-30 T 22-04-2016 IPR014720 Double-stranded RNA-binding domain HRM2_RS17820 26aade8c4aec5b6551c517eee917eb36 164 Gene3D G3DSA:3.30.230.10 78 158 3.8E-31 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HRM2_RS17820 26aade8c4aec5b6551c517eee917eb36 164 ProSitePatterns PS00585 Ribosomal protein S5 signature. 28 60 - T 22-04-2016 IPR018192 Ribosomal protein S5, N-terminal, conserved site HRM2_RS17820 26aade8c4aec5b6551c517eee917eb36 164 SUPERFAMILY SSF54768 11 76 5.34E-22 T 22-04-2016 HRM2_RS17820 26aade8c4aec5b6551c517eee917eb36 164 SUPERFAMILY SSF54211 79 158 4.8E-25 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS05650 574e44c7a3bb580997c3c71b4cfe94fb 127 Gene3D G3DSA:3.30.479.10 1 122 2.4E-41 T 22-04-2016 HRM2_RS05650 574e44c7a3bb580997c3c71b4cfe94fb 127 PANTHER PTHR12589 1 122 1.6E-41 T 22-04-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein HRM2_RS05650 574e44c7a3bb580997c3c71b4cfe94fb 127 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 3 95 1.6E-28 T 22-04-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein HRM2_RS05650 574e44c7a3bb580997c3c71b4cfe94fb 127 SUPERFAMILY SSF55620 1 122 7.78E-38 T 22-04-2016 HRM2_RS05650 574e44c7a3bb580997c3c71b4cfe94fb 127 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 4 122 1.3E-35 T 22-04-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein HRM2_RS05650 574e44c7a3bb580997c3c71b4cfe94fb 127 PIRSF PIRSF006113 1 125 6.2E-27 T 22-04-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein HRM2_RS20450 afeec6a075a9c7b25a0f3b863b461dc2 121 Pfam PF11964 SpoIIAA-like 12 119 8.7E-14 T 22-04-2016 IPR021866 SpoIIAA-like HRM2_RS20450 afeec6a075a9c7b25a0f3b863b461dc2 121 Gene3D G3DSA:3.40.50.10600 6 119 5.1E-15 T 22-04-2016 IPR021866 SpoIIAA-like HRM2_RS20450 afeec6a075a9c7b25a0f3b863b461dc2 121 SUPERFAMILY SSF52091 6 120 3.34E-21 T 22-04-2016 IPR002645 STAS domain HRM2_RS20960 54770dd1be9ad3a25b2105f285943cb6 402 SUPERFAMILY SSF55424 275 382 4.64E-15 T 22-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 HRM2_RS20960 54770dd1be9ad3a25b2105f285943cb6 402 Gene3D G3DSA:3.30.390.30 287 397 3.4E-17 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HRM2_RS20960 54770dd1be9ad3a25b2105f285943cb6 402 Gene3D G3DSA:3.50.50.60 17 51 1.7E-17 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS20960 54770dd1be9ad3a25b2105f285943cb6 402 Gene3D G3DSA:3.50.50.60 195 267 1.7E-17 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS20960 54770dd1be9ad3a25b2105f285943cb6 402 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 20 236 1.1E-42 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS20960 54770dd1be9ad3a25b2105f285943cb6 402 SUPERFAMILY SSF51905 18 267 4.91E-34 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS20960 54770dd1be9ad3a25b2105f285943cb6 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 186 202 1.6E-15 T 22-04-2016 HRM2_RS20960 54770dd1be9ad3a25b2105f285943cb6 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 97 115 1.6E-15 T 22-04-2016 HRM2_RS20960 54770dd1be9ad3a25b2105f285943cb6 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 212 234 1.6E-15 T 22-04-2016 HRM2_RS20960 54770dd1be9ad3a25b2105f285943cb6 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 50 68 1.6E-15 T 22-04-2016 HRM2_RS20960 54770dd1be9ad3a25b2105f285943cb6 402 Gene3D G3DSA:3.50.50.60 52 194 1.5E-40 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS20960 54770dd1be9ad3a25b2105f285943cb6 402 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 287 383 6.8E-8 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HRM2_RS20960 54770dd1be9ad3a25b2105f285943cb6 402 PANTHER PTHR22912 9 392 2.5E-91 T 22-04-2016 HRM2_RS20960 54770dd1be9ad3a25b2105f285943cb6 402 PANTHER PTHR22912:SF140 9 392 2.5E-91 T 22-04-2016 HRM2_RS15380 f0b41763f97deeee12876ed6eb39396a 436 PANTHER PTHR10625 1 340 2.3E-68 T 22-04-2016 IPR000286 Histone deacetylase superfamily HRM2_RS15380 f0b41763f97deeee12876ed6eb39396a 436 PRINTS PR01270 Histone deacetylase superfamily signature 230 240 1.5E-6 T 22-04-2016 IPR000286 Histone deacetylase superfamily HRM2_RS15380 f0b41763f97deeee12876ed6eb39396a 436 PRINTS PR01270 Histone deacetylase superfamily signature 144 159 1.5E-6 T 22-04-2016 IPR000286 Histone deacetylase superfamily HRM2_RS15380 f0b41763f97deeee12876ed6eb39396a 436 PRINTS PR01270 Histone deacetylase superfamily signature 110 133 1.5E-6 T 22-04-2016 IPR000286 Histone deacetylase superfamily HRM2_RS15380 f0b41763f97deeee12876ed6eb39396a 436 Pfam PF00850 Histone deacetylase domain 77 277 1.1E-58 T 22-04-2016 IPR023801 Histone deacetylase domain HRM2_RS15380 f0b41763f97deeee12876ed6eb39396a 436 SUPERFAMILY SSF52768 5 332 6.71E-87 T 22-04-2016 HRM2_RS15380 f0b41763f97deeee12876ed6eb39396a 436 Gene3D G3DSA:3.40.800.20 78 333 8.3E-74 T 22-04-2016 IPR023801 Histone deacetylase domain HRM2_RS15380 f0b41763f97deeee12876ed6eb39396a 436 PANTHER PTHR10625:SF104 1 340 2.3E-68 T 22-04-2016 HRM2_RS15380 f0b41763f97deeee12876ed6eb39396a 436 Gene3D G3DSA:3.40.800.20 3 66 3.4E-5 T 22-04-2016 IPR023801 Histone deacetylase domain HRM2_RS05335 fec478f0a4ae61e1b3f1665fc18582fe 125 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 1 105 32.222 T 22-04-2016 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19|UniPathway: UPA00031 HRM2_RS05335 fec478f0a4ae61e1b3f1665fc18582fe 125 PANTHER PTHR21256 1 104 1.4E-64 T 22-04-2016 HRM2_RS05335 fec478f0a4ae61e1b3f1665fc18582fe 125 SUPERFAMILY SSF141734 3 115 1.19E-48 T 22-04-2016 HRM2_RS05335 fec478f0a4ae61e1b3f1665fc18582fe 125 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 50 104 4.0E-18 T 22-04-2016 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19|UniPathway: UPA00031 HRM2_RS05335 fec478f0a4ae61e1b3f1665fc18582fe 125 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 27 101 1.2E-35 T 22-04-2016 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19|UniPathway: UPA00031 HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 Pfam PF02142 MGS-like domain 957 1041 3.6E-20 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1069 13.782 T 22-04-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 SUPERFAMILY SSF56059 128 400 6.54E-106 T 22-04-2016 HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 838 845 - T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 673 875 7.4E-39 T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 3.0E-70 T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 SUPERFAMILY SSF48108 395 553 9.55E-50 T 22-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 SMART SM01096 425 547 2.0E-64 T 22-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 PANTHER PTHR11405:SF5 1 1070 0.0 T 22-04-2016 HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 Gene3D G3DSA:1.10.1030.10 400 538 1.3E-51 T 22-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1062 13.052 T 22-04-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1053 0.0 T 22-04-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 PANTHER PTHR11405 1 1070 0.0 T 22-04-2016 HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 1.8E-61 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.8E-61 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 1.8E-61 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.8E-61 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 379 397 1.8E-61 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 1.8E-61 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 1.8E-61 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 Gene3D G3DSA:3.30.470.20 201 399 1.1E-73 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 Gene3D G3DSA:3.30.470.20 745 934 1.4E-76 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 SUPERFAMILY SSF56059 673 933 4.07E-103 T 22-04-2016 HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 SUPERFAMILY SSF52440 557 675 5.47E-51 T 22-04-2016 IPR016185 Pre-ATP-grasp domain HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 Gene3D G3DSA:3.40.50.1380 937 1073 2.9E-42 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 SUPERFAMILY SSF52440 1 127 6.47E-48 T 22-04-2016 IPR016185 Pre-ATP-grasp domain HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 Gene3D G3DSA:3.40.50.20 3 108 2.3E-41 T 22-04-2016 IPR016185 Pre-ATP-grasp domain HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 709 723 - T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 SUPERFAMILY SSF52335 935 1073 5.36E-39 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 Gene3D G3DSA:3.30.1490.20 141 200 1.3E-20 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 Gene3D G3DSA:3.30.1490.20 687 744 8.3E-27 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 SMART SM00851 955 1041 1.2E-28 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 Gene3D G3DSA:3.40.50.20 539 662 1.2E-61 T 22-04-2016 IPR016185 Pre-ATP-grasp domain HRM2_RS23620 02bd67ee55e07173e01aefb303a67199 1074 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 428 547 3.2E-43 T 22-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HRM2_RS24170 22b393df116df83e196462976d1c3a18 118 Gene3D G3DSA:3.90.580.10 3 91 5.9E-12 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS24170 22b393df116df83e196462976d1c3a18 118 Pfam PF01807 CHC2 zinc finger 10 90 3.1E-6 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS24170 22b393df116df83e196462976d1c3a18 118 SUPERFAMILY SSF57783 13 92 6.12E-11 T 22-04-2016 HRM2_RS08055 f7779b1a4e534e00dbc737a473f97788 662 Gene3D G3DSA:1.10.287.130 435 491 1.0E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS08055 f7779b1a4e534e00dbc737a473f97788 662 SUPERFAMILY SSF47384 433 502 4.32E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS08055 f7779b1a4e534e00dbc737a473f97788 662 Pfam PF00512 His Kinase A (phospho-acceptor) domain 440 503 4.2E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS08055 f7779b1a4e534e00dbc737a473f97788 662 SUPERFAMILY SSF55874 495 660 1.31E-35 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS08055 f7779b1a4e534e00dbc737a473f97788 662 Gene3D G3DSA:3.30.450.20 298 422 2.6E-18 T 22-04-2016 HRM2_RS08055 f7779b1a4e534e00dbc737a473f97788 662 Gene3D G3DSA:3.30.565.10 492 661 7.1E-37 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS08055 f7779b1a4e534e00dbc737a473f97788 662 SMART SM00387 547 662 6.3E-27 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS08055 f7779b1a4e534e00dbc737a473f97788 662 Pfam PF17203 Single cache domain 3 32 162 1.0E-7 T 22-04-2016 IPR033463 Single cache domain 3 HRM2_RS08055 f7779b1a4e534e00dbc737a473f97788 662 SMART SM00091 311 378 1.8E-5 T 22-04-2016 IPR000014 PAS domain HRM2_RS08055 f7779b1a4e534e00dbc737a473f97788 662 PRINTS PR00344 Bacterial sensor protein C-terminal signature 647 660 2.6E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS08055 f7779b1a4e534e00dbc737a473f97788 662 PRINTS PR00344 Bacterial sensor protein C-terminal signature 617 635 2.6E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS08055 f7779b1a4e534e00dbc737a473f97788 662 PRINTS PR00344 Bacterial sensor protein C-terminal signature 586 600 2.6E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS08055 f7779b1a4e534e00dbc737a473f97788 662 PRINTS PR00344 Bacterial sensor protein C-terminal signature 604 614 2.6E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS08055 f7779b1a4e534e00dbc737a473f97788 662 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 547 661 1.1E-19 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS08055 f7779b1a4e534e00dbc737a473f97788 662 SUPERFAMILY SSF55785 297 422 5.58E-18 T 22-04-2016 IPR000014 PAS domain HRM2_RS08055 f7779b1a4e534e00dbc737a473f97788 662 SMART SM00388 439 505 3.4E-15 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS08055 f7779b1a4e534e00dbc737a473f97788 662 Pfam PF08448 PAS fold 317 425 2.0E-10 T 22-04-2016 IPR013656 PAS fold-4 HRM2_RS08055 f7779b1a4e534e00dbc737a473f97788 662 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 308 431 7.2E-13 T 22-04-2016 IPR000014 PAS domain HRM2_RS08055 f7779b1a4e534e00dbc737a473f97788 662 PANTHER PTHR24423 19 27 1.0E-80 T 22-04-2016 HRM2_RS08055 f7779b1a4e534e00dbc737a473f97788 662 PANTHER PTHR24423 295 660 1.0E-80 T 22-04-2016 HRM2_RS04465 410c3f23b14053f083884e622da7abe2 349 Pfam PF00672 HAMP domain 273 339 4.1E-13 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS04465 410c3f23b14053f083884e622da7abe2 349 SMART SM00304 292 344 4.3E-9 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS04465 410c3f23b14053f083884e622da7abe2 349 SUPERFAMILY SSF158472 292 342 3.14E-9 T 22-04-2016 HRM2_RS04860 65b6bd4ee8ede903e082cabf5c225be4 362 PANTHER PTHR24220:SF284 1 227 1.7E-92 T 22-04-2016 HRM2_RS04860 65b6bd4ee8ede903e082cabf5c225be4 362 SUPERFAMILY SSF50331 242 356 2.98E-21 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal HRM2_RS04860 65b6bd4ee8ede903e082cabf5c225be4 362 Pfam PF03459 TOBE domain 294 356 1.7E-11 T 22-04-2016 IPR005116 Transport-associated OB, type 1 HRM2_RS04860 65b6bd4ee8ede903e082cabf5c225be4 362 Pfam PF00005 ABC transporter 26 160 6.9E-27 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS04860 65b6bd4ee8ede903e082cabf5c225be4 362 SUPERFAMILY SSF52540 6 225 4.14E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04860 65b6bd4ee8ede903e082cabf5c225be4 362 Gene3D G3DSA:3.40.50.300 25 229 1.2E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04860 65b6bd4ee8ede903e082cabf5c225be4 362 TIGRFAM TIGR02142 modC_ABC: molybdate ABC transporter, ATP-binding protein 3 355 2.5E-124 T 22-04-2016 IPR011868 Molybdate ABC transporter, ATP-binding protein GO:0005524|GO:0015098|GO:0015689|GO:0016020 HRM2_RS04860 65b6bd4ee8ede903e082cabf5c225be4 362 Gene3D G3DSA:2.40.50.100 283 353 2.7E-15 T 22-04-2016 HRM2_RS04860 65b6bd4ee8ede903e082cabf5c225be4 362 SMART SM00382 23 210 5.3E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS04860 65b6bd4ee8ede903e082cabf5c225be4 362 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS04860 65b6bd4ee8ede903e082cabf5c225be4 362 PANTHER PTHR24220 1 227 1.7E-92 T 22-04-2016 HRM2_RS03500 4cd2d8a783f3d3f50c7e941cece062eb 103 Pfam PF00011 Hsp20/alpha crystallin family 22 102 2.2E-4 T 22-04-2016 IPR002068 Alpha crystallin/Hsp20 domain HRM2_RS03500 4cd2d8a783f3d3f50c7e941cece062eb 103 SUPERFAMILY SSF49764 21 96 1.64E-12 T 22-04-2016 IPR008978 HSP20-like chaperone HRM2_RS03500 4cd2d8a783f3d3f50c7e941cece062eb 103 Gene3D G3DSA:2.60.40.790 21 56 2.4E-4 T 22-04-2016 IPR008978 HSP20-like chaperone HRM2_RS16080 a93f4f35bb120511c235984a479c505a 246 PANTHER PTHR10434 1 239 9.0E-53 T 22-04-2016 HRM2_RS16080 a93f4f35bb120511c235984a479c505a 246 Pfam PF01553 Acyltransferase 63 194 4.2E-30 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 HRM2_RS16080 a93f4f35bb120511c235984a479c505a 246 SMART SM00563 77 197 4.4E-40 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 HRM2_RS16080 a93f4f35bb120511c235984a479c505a 246 SUPERFAMILY SSF69593 15 224 6.28E-43 T 22-04-2016 HRM2_RS16080 a93f4f35bb120511c235984a479c505a 246 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 61 194 1.7E-32 T 22-04-2016 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|Reactome: REACT_22258|UniPathway: UPA00557 HRM2_RS16080 a93f4f35bb120511c235984a479c505a 246 Gene3D G3DSA:3.40.1130.10 69 226 8.4E-25 T 22-04-2016 HRM2_RS17625 8871258487338c6a7c47db582d694ac4 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.5E-8 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS17625 8871258487338c6a7c47db582d694ac4 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.5E-8 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS17625 8871258487338c6a7c47db582d694ac4 197 SUPERFAMILY SSF48498 86 196 1.99E-21 T 22-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal HRM2_RS17625 8871258487338c6a7c47db582d694ac4 197 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 58 - T 22-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site HRM2_RS17625 8871258487338c6a7c47db582d694ac4 197 SUPERFAMILY SSF46689 7 78 2.67E-15 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS17625 8871258487338c6a7c47db582d694ac4 197 PANTHER PTHR30055 1 189 1.5E-37 T 22-04-2016 HRM2_RS17625 8871258487338c6a7c47db582d694ac4 197 Pfam PF08359 YsiA-like protein, C-terminal region 67 193 2.0E-26 T 22-04-2016 IPR013570 Transcription regulator YsiA, C-terminal HRM2_RS17625 8871258487338c6a7c47db582d694ac4 197 Gene3D G3DSA:1.10.357.10 56 196 3.3E-33 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HRM2_RS17625 8871258487338c6a7c47db582d694ac4 197 Gene3D G3DSA:1.10.10.60 5 55 8.2E-16 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS17625 8871258487338c6a7c47db582d694ac4 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 58 1.0E-12 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS17625 8871258487338c6a7c47db582d694ac4 197 PANTHER PTHR30055:SF84 1 189 1.5E-37 T 22-04-2016 HRM2_RS12220 1fd9eac53e1ca32025648b9fcf3a178f 500 PANTHER PTHR23501 9 495 6.5E-115 T 22-04-2016 HRM2_RS12220 1fd9eac53e1ca32025648b9fcf3a178f 500 Pfam PF07690 Major Facilitator Superfamily 17 408 2.1E-47 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS12220 1fd9eac53e1ca32025648b9fcf3a178f 500 SUPERFAMILY SSF103473 469 493 1.83E-59 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS12220 1fd9eac53e1ca32025648b9fcf3a178f 500 SUPERFAMILY SSF103473 9 199 1.83E-59 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS12220 1fd9eac53e1ca32025648b9fcf3a178f 500 SUPERFAMILY SSF103473 248 418 1.83E-59 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS12220 1fd9eac53e1ca32025648b9fcf3a178f 500 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 14 483 2.2E-70 T 22-04-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 HRM2_RS12220 1fd9eac53e1ca32025648b9fcf3a178f 500 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 159 9.8E-9 T 22-04-2016 HRM2_RS12220 1fd9eac53e1ca32025648b9fcf3a178f 500 PRINTS PR01036 Tetracycline resistance protein TetB signature 105 125 9.8E-9 T 22-04-2016 HRM2_RS12220 1fd9eac53e1ca32025648b9fcf3a178f 500 PRINTS PR01036 Tetracycline resistance protein TetB signature 15 39 9.8E-9 T 22-04-2016 HRM2_RS12220 1fd9eac53e1ca32025648b9fcf3a178f 500 PRINTS PR01036 Tetracycline resistance protein TetB signature 399 418 9.8E-9 T 22-04-2016 HRM2_RS12220 1fd9eac53e1ca32025648b9fcf3a178f 500 Gene3D G3DSA:1.20.1250.20 470 493 5.1E-21 T 22-04-2016 HRM2_RS12220 1fd9eac53e1ca32025648b9fcf3a178f 500 Gene3D G3DSA:1.20.1250.20 11 191 1.2E-28 T 22-04-2016 HRM2_RS12220 1fd9eac53e1ca32025648b9fcf3a178f 500 Gene3D G3DSA:1.20.1250.20 265 418 5.1E-21 T 22-04-2016 HRM2_RS23830 b0c26cf3fcd4d1d5bd3fbe3b47d4a85c 169 PANTHER PTHR35011 2 154 3.2E-26 T 22-04-2016 HRM2_RS23830 b0c26cf3fcd4d1d5bd3fbe3b47d4a85c 169 PANTHER PTHR35011:SF2 2 154 3.2E-26 T 22-04-2016 HRM2_RS23830 b0c26cf3fcd4d1d5bd3fbe3b47d4a85c 169 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 26 153 2.0E-32 T 22-04-2016 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component HRM2_RS23105 ac28f3c3a84fb18594ad1256f19b463e 380 PANTHER PTHR30483:SF18 1 380 5.9E-141 T 22-04-2016 HRM2_RS23105 ac28f3c3a84fb18594ad1256f19b463e 380 SUPERFAMILY SSF53822 27 377 1.49E-83 T 22-04-2016 IPR028082 Periplasmic binding protein-like I HRM2_RS23105 ac28f3c3a84fb18594ad1256f19b463e 380 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 68 86 9.4E-7 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HRM2_RS23105 ac28f3c3a84fb18594ad1256f19b463e 380 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 254 272 9.4E-7 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HRM2_RS23105 ac28f3c3a84fb18594ad1256f19b463e 380 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 49 65 9.4E-7 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HRM2_RS23105 ac28f3c3a84fb18594ad1256f19b463e 380 Gene3D G3DSA:3.40.50.2300 27 224 5.6E-55 T 22-04-2016 HRM2_RS23105 ac28f3c3a84fb18594ad1256f19b463e 380 PANTHER PTHR30483 1 380 5.9E-141 T 22-04-2016 HRM2_RS23105 ac28f3c3a84fb18594ad1256f19b463e 380 Pfam PF13458 Periplasmic binding protein 27 369 2.2E-65 T 22-04-2016 IPR028081 Leucine-binding protein domain HRM2_RS08775 d5795e05a1de17b89cdca84e2b927420 278 PANTHER PTHR37945 11 278 1.6E-84 T 22-04-2016 HRM2_RS08775 d5795e05a1de17b89cdca84e2b927420 278 Gene3D G3DSA:3.40.190.10 23 156 4.1E-37 T 22-04-2016 HRM2_RS08775 d5795e05a1de17b89cdca84e2b927420 278 Pfam PF12849 PBP superfamily domain 25 255 1.8E-24 T 22-04-2016 IPR024370 PBP domain HRM2_RS08775 d5795e05a1de17b89cdca84e2b927420 278 Gene3D G3DSA:3.40.190.10 193 277 4.1E-15 T 22-04-2016 HRM2_RS08775 d5795e05a1de17b89cdca84e2b927420 278 SUPERFAMILY SSF53850 32 266 6.29E-23 T 22-04-2016 HRM2_RS24120 beaaed7e726dfaaa905aef49e9d333b6 291 PANTHER PTHR11795 4 285 1.6E-80 T 22-04-2016 HRM2_RS24120 beaaed7e726dfaaa905aef49e9d333b6 291 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 276 2.8E-39 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 HRM2_RS24120 beaaed7e726dfaaa905aef49e9d333b6 291 PANTHER PTHR11795:SF371 4 285 1.6E-80 T 22-04-2016 HRM2_RS01395 f53fa99d0af1ff03339d45e62cedd750 507 SUPERFAMILY SSF52540 195 439 1.18E-74 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01395 f53fa99d0af1ff03339d45e62cedd750 507 PANTHER PTHR32071 150 507 1.4E-157 T 22-04-2016 HRM2_RS01395 f53fa99d0af1ff03339d45e62cedd750 507 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 465 482 5.0E-6 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS01395 f53fa99d0af1ff03339d45e62cedd750 507 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 482 502 5.0E-6 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS01395 f53fa99d0af1ff03339d45e62cedd750 507 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 220 233 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS01395 f53fa99d0af1ff03339d45e62cedd750 507 Pfam PF02954 Bacterial regulatory protein, Fis family 462 495 1.6E-6 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS01395 f53fa99d0af1ff03339d45e62cedd750 507 Pfam PF01590 GAF domain 54 162 1.2E-8 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS01395 f53fa99d0af1ff03339d45e62cedd750 507 SUPERFAMILY SSF46689 409 502 9.41E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS01395 f53fa99d0af1ff03339d45e62cedd750 507 Gene3D G3DSA:1.10.8.60 370 442 7.1E-26 T 22-04-2016 HRM2_RS01395 f53fa99d0af1ff03339d45e62cedd750 507 Pfam PF00158 Sigma-54 interaction domain 196 362 6.6E-73 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS01395 f53fa99d0af1ff03339d45e62cedd750 507 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 409 418 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS01395 f53fa99d0af1ff03339d45e62cedd750 507 Gene3D G3DSA:3.40.50.300 193 368 4.4E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01395 f53fa99d0af1ff03339d45e62cedd750 507 Gene3D G3DSA:1.10.10.60 445 502 3.5E-8 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS01395 f53fa99d0af1ff03339d45e62cedd750 507 SMART SM00065 22 173 1.3E-19 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS01395 f53fa99d0af1ff03339d45e62cedd750 507 SUPERFAMILY SSF55781 4 173 7.57E-23 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS01395 f53fa99d0af1ff03339d45e62cedd750 507 Gene3D G3DSA:3.30.450.40 3 164 4.7E-31 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS01395 f53fa99d0af1ff03339d45e62cedd750 507 SMART SM00382 216 360 2.9E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS25055 5d2b67b3cbd6c8cf418dbd14d3e8dba1 508 Gene3D G3DSA:3.40.50.150 136 333 8.4E-37 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS25055 5d2b67b3cbd6c8cf418dbd14d3e8dba1 508 Pfam PF16864 Dimerisation domain 18 97 2.4E-11 T 22-04-2016 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain HRM2_RS25055 5d2b67b3cbd6c8cf418dbd14d3e8dba1 508 PANTHER PTHR11746:SF63 15 356 9.6E-37 T 22-04-2016 HRM2_RS25055 5d2b67b3cbd6c8cf418dbd14d3e8dba1 508 Gene3D G3DSA:1.10.10.10 19 106 2.2E-14 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS25055 5d2b67b3cbd6c8cf418dbd14d3e8dba1 508 Pfam PF00891 O-methyltransferase 165 312 5.6E-22 T 22-04-2016 IPR001077 O-methyltransferase, family 2 GO:0008171 HRM2_RS25055 5d2b67b3cbd6c8cf418dbd14d3e8dba1 508 SUPERFAMILY SSF53335 136 328 5.93E-33 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS25055 5d2b67b3cbd6c8cf418dbd14d3e8dba1 508 Pfam PF10050 Predicted metal-binding protein (DUF2284) 362 506 6.7E-37 T 22-04-2016 IPR019271 Protein of unknown function DUF2284, metal-binding HRM2_RS25055 5d2b67b3cbd6c8cf418dbd14d3e8dba1 508 PANTHER PTHR11746 15 356 9.6E-37 T 22-04-2016 HRM2_RS25055 5d2b67b3cbd6c8cf418dbd14d3e8dba1 508 SUPERFAMILY SSF46785 15 97 1.61E-11 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS07400 e9420f1228c9a03aa8551f69a3ad060c 73 Pfam PF09720 Putative addiction module component 10 64 2.7E-11 T 22-04-2016 IPR013406 Conserved hypothetical protein CHP02574, addiction module HRM2_RS15310 6bf684d1f1e748ef3d06cae8f9523b5d 84 SUPERFAMILY SSF54565 3 79 3.53E-31 T 22-04-2016 IPR023803 Ribosomal protein S16 domain HRM2_RS15310 6bf684d1f1e748ef3d06cae8f9523b5d 84 PANTHER PTHR12919 2 79 6.7E-43 T 22-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS15310 6bf684d1f1e748ef3d06cae8f9523b5d 84 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 23.773 T 22-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS15310 6bf684d1f1e748ef3d06cae8f9523b5d 84 Gene3D G3DSA:3.30.1320.10 3 81 8.3E-33 T 22-04-2016 IPR023803 Ribosomal protein S16 domain HRM2_RS15310 6bf684d1f1e748ef3d06cae8f9523b5d 84 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 1.2E-31 T 22-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS15310 6bf684d1f1e748ef3d06cae8f9523b5d 84 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 22-04-2016 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS15310 6bf684d1f1e748ef3d06cae8f9523b5d 84 Pfam PF00886 Ribosomal protein S16 9 67 2.2E-24 T 22-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS16340 9d66770a579bb03ccf65e299d4dc9ddf 232 SUPERFAMILY SSF48008 98 229 4.45E-24 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS16340 9d66770a579bb03ccf65e299d4dc9ddf 232 Gene3D G3DSA:1.10.10.10 1 77 2.2E-25 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS16340 9d66770a579bb03ccf65e299d4dc9ddf 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 2.1E-7 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS16340 9d66770a579bb03ccf65e299d4dc9ddf 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 2.1E-7 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS16340 9d66770a579bb03ccf65e299d4dc9ddf 232 SUPERFAMILY SSF46785 6 80 2.23E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS16340 9d66770a579bb03ccf65e299d4dc9ddf 232 SMART SM00895 100 226 5.7E-20 T 22-04-2016 IPR011711 GntR, C-terminal HRM2_RS16340 9d66770a579bb03ccf65e299d4dc9ddf 232 Pfam PF07729 FCD domain 100 225 2.1E-20 T 22-04-2016 IPR011711 GntR, C-terminal HRM2_RS16340 9d66770a579bb03ccf65e299d4dc9ddf 232 SMART SM00345 17 76 3.0E-20 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS16340 9d66770a579bb03ccf65e299d4dc9ddf 232 PANTHER PTHR11751 14 116 9.8E-28 T 22-04-2016 HRM2_RS16340 9d66770a579bb03ccf65e299d4dc9ddf 232 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 2.8E-19 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS16340 9d66770a579bb03ccf65e299d4dc9ddf 232 Gene3D G3DSA:1.20.120.530 96 229 5.7E-23 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS17680 3906e9fa030a5f7678dd3ea1b9949b61 123 SUPERFAMILY SSF55486 3 114 1.15E-35 T 22-04-2016 HRM2_RS17680 3906e9fa030a5f7678dd3ea1b9949b61 123 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 1 119 18.625 T 22-04-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 HRM2_RS17680 3906e9fa030a5f7678dd3ea1b9949b61 123 Gene3D G3DSA:3.40.390.30 1 112 2.3E-38 T 22-04-2016 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 HRM2_RS17680 3906e9fa030a5f7678dd3ea1b9949b61 123 PANTHER PTHR22881 1 111 1.9E-38 T 22-04-2016 HRM2_RS17680 3906e9fa030a5f7678dd3ea1b9949b61 123 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 83 93 - T 22-04-2016 IPR020549 Endoribonuclease YbeY, conserved site HRM2_RS17680 3906e9fa030a5f7678dd3ea1b9949b61 123 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 7 112 1.9E-31 T 22-04-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 HRM2_RS17680 3906e9fa030a5f7678dd3ea1b9949b61 123 Pfam PF02130 Uncharacterized protein family UPF0054 6 111 1.3E-33 T 22-04-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 HRM2_RS16755 a846654a3e6ee463743caf4c0daeea8c 312 SUPERFAMILY SSF103642 268 287 1.01E-7 T 22-04-2016 HRM2_RS16755 a846654a3e6ee463743caf4c0daeea8c 312 Pfam PF02810 SEC-C motif 269 287 2.6E-10 T 22-04-2016 IPR004027 SEC-C motif HRM2_RS16755 a846654a3e6ee463743caf4c0daeea8c 312 PANTHER PTHR33747 257 287 4.1E-12 T 22-04-2016 HRM2_RS16755 a846654a3e6ee463743caf4c0daeea8c 312 Gene3D G3DSA:3.10.450.50 223 287 4.9E-13 T 22-04-2016 IPR032710 NTF2-like domain HRM2_RS16755 a846654a3e6ee463743caf4c0daeea8c 312 PANTHER PTHR33747:SF1 257 287 4.1E-12 T 22-04-2016 HRM2_RS13450 42ea8f50849d4350cbae583a738d7e18 523 PANTHER PTHR11206:SF90 83 88 6.7E-40 T 22-04-2016 HRM2_RS13450 42ea8f50849d4350cbae583a738d7e18 523 PANTHER PTHR11206:SF90 226 451 6.7E-40 T 22-04-2016 HRM2_RS13450 42ea8f50849d4350cbae583a738d7e18 523 PANTHER PTHR11206:SF90 57 66 6.7E-40 T 22-04-2016 HRM2_RS13450 42ea8f50849d4350cbae583a738d7e18 523 Pfam PF03023 MviN-like protein 37 473 1.8E-100 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ HRM2_RS13450 42ea8f50849d4350cbae583a738d7e18 523 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 12 500 1.2E-115 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ HRM2_RS13450 42ea8f50849d4350cbae583a738d7e18 523 PRINTS PR01806 Virulence factor MviN signature 418 435 3.3E-51 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ HRM2_RS13450 42ea8f50849d4350cbae583a738d7e18 523 PRINTS PR01806 Virulence factor MviN signature 142 166 3.3E-51 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ HRM2_RS13450 42ea8f50849d4350cbae583a738d7e18 523 PRINTS PR01806 Virulence factor MviN signature 366 385 3.3E-51 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ HRM2_RS13450 42ea8f50849d4350cbae583a738d7e18 523 PRINTS PR01806 Virulence factor MviN signature 166 187 3.3E-51 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ HRM2_RS13450 42ea8f50849d4350cbae583a738d7e18 523 PRINTS PR01806 Virulence factor MviN signature 61 77 3.3E-51 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ HRM2_RS13450 42ea8f50849d4350cbae583a738d7e18 523 PRINTS PR01806 Virulence factor MviN signature 42 61 3.3E-51 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ HRM2_RS13450 42ea8f50849d4350cbae583a738d7e18 523 PRINTS PR01806 Virulence factor MviN signature 268 294 3.3E-51 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ HRM2_RS13450 42ea8f50849d4350cbae583a738d7e18 523 PIRSF PIRSF002869 7 518 1.1E-135 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ HRM2_RS13450 42ea8f50849d4350cbae583a738d7e18 523 PANTHER PTHR11206 83 88 6.7E-40 T 22-04-2016 HRM2_RS13450 42ea8f50849d4350cbae583a738d7e18 523 PANTHER PTHR11206 226 451 6.7E-40 T 22-04-2016 HRM2_RS13450 42ea8f50849d4350cbae583a738d7e18 523 PANTHER PTHR11206 57 66 6.7E-40 T 22-04-2016 HRM2_RS03455 6595c7a7050fdee9436114c0213e7539 610 SUPERFAMILY SSF116726 257 314 8.89E-5 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS03455 6595c7a7050fdee9436114c0213e7539 610 PANTHER PTHR10283:SF100 372 607 1.0E-90 T 22-04-2016 HRM2_RS03455 6595c7a7050fdee9436114c0213e7539 610 PANTHER PTHR10283:SF100 7 238 1.0E-90 T 22-04-2016 HRM2_RS03455 6595c7a7050fdee9436114c0213e7539 610 Gene3D G3DSA:3.30.70.1450 332 404 8.4E-16 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS03455 6595c7a7050fdee9436114c0213e7539 610 Gene3D G3DSA:3.30.70.1450 258 315 7.5E-7 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS03455 6595c7a7050fdee9436114c0213e7539 610 SUPERFAMILY SSF116726 331 403 8.76E-15 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS03455 6595c7a7050fdee9436114c0213e7539 610 Pfam PF03600 Citrate transporter 20 556 5.7E-46 T 22-04-2016 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 HRM2_RS03455 6595c7a7050fdee9436114c0213e7539 610 Pfam PF02080 TrkA-C domain 332 399 3.6E-8 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS03455 6595c7a7050fdee9436114c0213e7539 610 PANTHER PTHR10283 372 607 1.0E-90 T 22-04-2016 HRM2_RS03455 6595c7a7050fdee9436114c0213e7539 610 PANTHER PTHR10283 7 238 1.0E-90 T 22-04-2016 HRM2_RS21830 fa21691f0d0834bf14f5222ff3066ef7 89 Pfam PF08681 Protein of unknown function (DUF1778) 5 79 1.9E-17 T 22-04-2016 IPR014795 Vibrio phage ICP1, Orf50 HRM2_RS21830 fa21691f0d0834bf14f5222ff3066ef7 89 SUPERFAMILY SSF47598 2 79 1.6E-15 T 22-04-2016 IPR010985 Ribbon-helix-helix GO:0006355 HRM2_RS21830 fa21691f0d0834bf14f5222ff3066ef7 89 Gene3D G3DSA:1.20.5.780 2 81 3.3E-17 T 22-04-2016 HRM2_RS05795 accbcdc49a20128107c6c371932480a7 939 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 32 43 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS05795 accbcdc49a20128107c6c371932480a7 939 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 522 837 1.1E-12 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS05795 accbcdc49a20128107c6c371932480a7 939 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 68 348 3.3E-8 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS05795 accbcdc49a20128107c6c371932480a7 939 Gene3D G3DSA:3.50.50.60 308 358 3.3E-8 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS05795 accbcdc49a20128107c6c371932480a7 939 Gene3D G3DSA:3.50.50.60 105 150 3.3E-8 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS05795 accbcdc49a20128107c6c371932480a7 939 Gene3D G3DSA:3.50.50.60 3 22 3.3E-8 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS05795 accbcdc49a20128107c6c371932480a7 939 Gene3D G3DSA:3.50.50.60 725 849 7.3E-7 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS05795 accbcdc49a20128107c6c371932480a7 939 Gene3D G3DSA:3.40.50.720 519 689 2.7E-29 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS05795 accbcdc49a20128107c6c371932480a7 939 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 903 914 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS05795 accbcdc49a20128107c6c371932480a7 939 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 866 877 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS05795 accbcdc49a20128107c6c371932480a7 939 PANTHER PTHR10742:SF263 443 556 1.4E-43 T 22-04-2016 HRM2_RS05795 accbcdc49a20128107c6c371932480a7 939 SUPERFAMILY SSF51971 103 356 3.18E-7 T 22-04-2016 HRM2_RS05795 accbcdc49a20128107c6c371932480a7 939 Pfam PF12838 4Fe-4S dicluster domain 31 98 6.3E-7 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS05795 accbcdc49a20128107c6c371932480a7 939 Pfam PF12838 4Fe-4S dicluster domain 866 915 3.2E-9 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS05795 accbcdc49a20128107c6c371932480a7 939 Gene3D G3DSA:3.30.70.20 863 925 1.3E-15 T 22-04-2016 HRM2_RS05795 accbcdc49a20128107c6c371932480a7 939 Gene3D G3DSA:3.30.70.20 182 206 1.3E-15 T 22-04-2016 HRM2_RS05795 accbcdc49a20128107c6c371932480a7 939 SUPERFAMILY SSF51905 517 843 2.85E-30 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS05795 accbcdc49a20128107c6c371932480a7 939 SUPERFAMILY SSF54862 862 925 7.39E-14 T 22-04-2016 HRM2_RS05795 accbcdc49a20128107c6c371932480a7 939 PANTHER PTHR10742 443 556 1.4E-43 T 22-04-2016 HRM2_RS05795 accbcdc49a20128107c6c371932480a7 939 SUPERFAMILY SSF54862 14 167 1.47E-24 T 22-04-2016 HRM2_RS05795 accbcdc49a20128107c6c371932480a7 939 Gene3D G3DSA:3.30.70.20 26 102 3.9E-15 T 22-04-2016 HRM2_RS01130 a3118f944b445ec43d370236731d72f1 261 SMART SM00382 27 243 2.8E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS01130 a3118f944b445ec43d370236731d72f1 261 Pfam PF00005 ABC transporter 18 166 1.7E-28 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS01130 a3118f944b445ec43d370236731d72f1 261 Gene3D G3DSA:3.40.50.300 5 237 2.9E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01130 a3118f944b445ec43d370236731d72f1 261 PANTHER PTHR24220:SF266 4 250 9.9E-76 T 22-04-2016 HRM2_RS01130 a3118f944b445ec43d370236731d72f1 261 PANTHER PTHR24220 4 250 9.9E-76 T 22-04-2016 HRM2_RS01130 a3118f944b445ec43d370236731d72f1 261 SUPERFAMILY SSF52540 5 230 1.5E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14300 915dfff3564b150d3088f4802f5a5a1f 247 PIRSF PIRSF006325 1 242 3.3E-77 T 22-04-2016 IPR005271 tRNA (cmo5U34)-methyltransferase GO:0002098|GO:0016300 HRM2_RS14300 915dfff3564b150d3088f4802f5a5a1f 247 Pfam PF13649 Methyltransferase domain 59 157 6.7E-11 T 22-04-2016 HRM2_RS14300 915dfff3564b150d3088f4802f5a5a1f 247 PANTHER PTHR10108:SF809 3 240 7.9E-47 T 22-04-2016 HRM2_RS14300 915dfff3564b150d3088f4802f5a5a1f 247 TIGRFAM TIGR00740 TIGR00740: tRNA (cmo5U34)-methyltransferase 3 241 1.9E-71 T 22-04-2016 IPR005271 tRNA (cmo5U34)-methyltransferase GO:0002098|GO:0016300 HRM2_RS14300 915dfff3564b150d3088f4802f5a5a1f 247 SUPERFAMILY SSF53335 18 241 5.2E-34 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS14300 915dfff3564b150d3088f4802f5a5a1f 247 PANTHER PTHR10108 3 240 7.9E-47 T 22-04-2016 HRM2_RS14300 915dfff3564b150d3088f4802f5a5a1f 247 Gene3D G3DSA:3.40.50.150 19 241 2.2E-49 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS14300 915dfff3564b150d3088f4802f5a5a1f 247 Hamap MF_01589 tRNA (cmo5U34)-methyltransferase [cmoA]. 2 241 36.372 T 22-04-2016 IPR005271 tRNA (cmo5U34)-methyltransferase GO:0002098|GO:0016300 HRM2_RS04420 6692dd96b5106cf84bb2ab1ee8c570ea 221 PANTHER PTHR18901 1 207 2.0E-79 T 22-04-2016 HRM2_RS04420 6692dd96b5106cf84bb2ab1ee8c570ea 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 185 6.0E-26 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS04420 6692dd96b5106cf84bb2ab1ee8c570ea 221 Gene3D G3DSA:3.40.50.1000 79 212 4.4E-37 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS04420 6692dd96b5106cf84bb2ab1ee8c570ea 221 SUPERFAMILY SSF56784 6 212 5.91E-48 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS04420 6692dd96b5106cf84bb2ab1ee8c570ea 221 PANTHER PTHR18901:SF23 1 207 2.0E-79 T 22-04-2016 HRM2_RS04420 6692dd96b5106cf84bb2ab1ee8c570ea 221 Gene3D G3DSA:1.10.150.240 18 78 6.7E-19 T 22-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 HRM2_RS16360 a3fde45c27bfcc05728f9724b4c09d1c 361 Gene3D G3DSA:3.20.20.70 24 354 3.5E-56 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS16360 a3fde45c27bfcc05728f9724b4c09d1c 361 Pfam PF04055 Radical SAM superfamily 68 239 3.2E-13 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS16360 a3fde45c27bfcc05728f9724b4c09d1c 361 PANTHER PTHR22976:SF29 11 361 7.7E-175 T 22-04-2016 HRM2_RS16360 a3fde45c27bfcc05728f9724b4c09d1c 361 TIGRFAM TIGR03699 menaquin_MqnC: dehypoxanthine futalosine cyclase 24 360 1.5E-148 T 22-04-2016 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374|UniPathway: UPA00079 HRM2_RS16360 a3fde45c27bfcc05728f9724b4c09d1c 361 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 60 361 1.4E-119 T 22-04-2016 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198|UniPathway: UPA00072 HRM2_RS16360 a3fde45c27bfcc05728f9724b4c09d1c 361 PIRSF PIRSF004762 2 360 4.7E-107 T 22-04-2016 IPR005244 FO synthase, subunit 2-like GO:0016765|GO:0051188|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198|UniPathway: UPA00072 HRM2_RS16360 a3fde45c27bfcc05728f9724b4c09d1c 361 Hamap MF_00992 Cyclic dehypoxanthine futalosine synthase [mqnC]. 23 361 51.198 T 22-04-2016 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374|UniPathway: UPA00079 HRM2_RS16360 a3fde45c27bfcc05728f9724b4c09d1c 361 SUPERFAMILY SSF102114 24 354 6.02E-46 T 22-04-2016 HRM2_RS16360 a3fde45c27bfcc05728f9724b4c09d1c 361 PANTHER PTHR22976 11 361 7.7E-175 T 22-04-2016 HRM2_RS10780 07e51f39a74e5b0aa475c0126e402f14 388 PANTHER PTHR23505:SF8 11 387 3.6E-44 T 22-04-2016 HRM2_RS10780 07e51f39a74e5b0aa475c0126e402f14 388 Pfam PF07690 Major Facilitator Superfamily 17 349 6.9E-30 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS10780 07e51f39a74e5b0aa475c0126e402f14 388 PANTHER PTHR23505 11 387 3.6E-44 T 22-04-2016 HRM2_RS10780 07e51f39a74e5b0aa475c0126e402f14 388 Gene3D G3DSA:1.20.1250.20 210 384 1.8E-17 T 22-04-2016 HRM2_RS10780 07e51f39a74e5b0aa475c0126e402f14 388 Gene3D G3DSA:1.20.1250.20 10 182 8.6E-23 T 22-04-2016 HRM2_RS10780 07e51f39a74e5b0aa475c0126e402f14 388 SUPERFAMILY SSF103473 5 381 1.05E-48 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS09235 a04b3e7744a548d11d3cf232aae2a26e 373 PANTHER PTHR13504 41 372 6.7E-40 T 22-04-2016 HRM2_RS09235 a04b3e7744a548d11d3cf232aae2a26e 373 SUPERFAMILY SSF140931 98 293 4.32E-37 T 22-04-2016 IPR003812 Fido domain HRM2_RS09235 a04b3e7744a548d11d3cf232aae2a26e 373 Pfam PF02661 Fic/DOC family 122 224 1.4E-18 T 22-04-2016 IPR003812 Fido domain HRM2_RS09235 a04b3e7744a548d11d3cf232aae2a26e 373 PIRSF PIRSF038925 1 373 6.5E-98 T 22-04-2016 IPR026287 Adenosine monophosphate-protein transferase HRM2_RS09235 a04b3e7744a548d11d3cf232aae2a26e 373 Gene3D G3DSA:1.10.3290.10 32 294 4.4E-51 T 22-04-2016 IPR003812 Fido domain HRM2_RS09235 a04b3e7744a548d11d3cf232aae2a26e 373 PANTHER PTHR13504:SF32 41 372 6.7E-40 T 22-04-2016 HRM2_RS09235 a04b3e7744a548d11d3cf232aae2a26e 373 Pfam PF13784 Fic/DOC family N-terminal 28 113 1.2E-20 T 22-04-2016 IPR025758 Fic/DOC N-terminal HRM2_RS12420 3f039cfcbcbdb7c82f82817e1f34f034 443 Gene3D G3DSA:3.40.640.10 98 335 2.3E-15 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS12420 3f039cfcbcbdb7c82f82817e1f34f034 443 Pfam PF02347 Glycine cleavage system P-protein 1 438 7.6E-115 T 22-04-2016 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 HRM2_RS12420 3f039cfcbcbdb7c82f82817e1f34f034 443 SUPERFAMILY SSF53383 1 440 4.1E-94 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS12420 3f039cfcbcbdb7c82f82817e1f34f034 443 PIRSF PIRSF006815 1 443 2.3E-161 T 22-04-2016 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 HRM2_RS12420 3f039cfcbcbdb7c82f82817e1f34f034 443 PANTHER PTHR11773:SF2 1 441 1.6E-171 T 22-04-2016 HRM2_RS12420 3f039cfcbcbdb7c82f82817e1f34f034 443 PANTHER PTHR11773 1 441 1.6E-171 T 22-04-2016 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 HRM2_RS02670 937d3f4ce0dad73850f260947e8e3c22 256 SMART SM00382 41 236 7.1E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS02670 937d3f4ce0dad73850f260947e8e3c22 256 PIRSF PIRSF039085 13 256 1.1E-109 T 22-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 HRM2_RS02670 937d3f4ce0dad73850f260947e8e3c22 256 PANTHER PTHR24220 18 255 2.7E-163 T 22-04-2016 HRM2_RS02670 937d3f4ce0dad73850f260947e8e3c22 256 Gene3D G3DSA:3.40.50.300 15 252 2.0E-82 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02670 937d3f4ce0dad73850f260947e8e3c22 256 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS02670 937d3f4ce0dad73850f260947e8e3c22 256 PANTHER PTHR24220:SF490 18 255 2.7E-163 T 22-04-2016 HRM2_RS02670 937d3f4ce0dad73850f260947e8e3c22 256 SUPERFAMILY SSF52540 16 250 1.27E-78 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02670 937d3f4ce0dad73850f260947e8e3c22 256 Pfam PF00005 ABC transporter 32 180 3.9E-38 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS18405 9c454f992f84298d7c477ec4f1fd5977 96 Pfam PF02049 Flagellar hook-basal body complex protein FliE 23 96 4.1E-20 T 22-04-2016 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 HRM2_RS18405 9c454f992f84298d7c477ec4f1fd5977 96 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 5 96 14.113 T 22-04-2016 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 HRM2_RS18405 9c454f992f84298d7c477ec4f1fd5977 96 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 23 96 1.2E-16 T 22-04-2016 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 HRM2_RS18405 9c454f992f84298d7c477ec4f1fd5977 96 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 60 76 9.9E-9 T 22-04-2016 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 HRM2_RS18405 9c454f992f84298d7c477ec4f1fd5977 96 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 27 43 9.9E-9 T 22-04-2016 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 HRM2_RS18405 9c454f992f84298d7c477ec4f1fd5977 96 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 81 94 9.9E-9 T 22-04-2016 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 HRM2_RS18405 9c454f992f84298d7c477ec4f1fd5977 96 PANTHER PTHR34653 24 96 4.0E-15 T 22-04-2016 HRM2_RS20700 4213b89d25042713c36e877376f06db5 124 TIGRFAM TIGR00320 dfx_rbo: desulfoferrodoxin 1 123 4.1E-55 T 22-04-2016 IPR004793 Desulfoferrodoxin GO:0005506|GO:0019430 HRM2_RS20700 4213b89d25042713c36e877376f06db5 124 SUPERFAMILY SSF49367 40 123 3.01E-33 T 22-04-2016 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 HRM2_RS20700 4213b89d25042713c36e877376f06db5 124 Gene3D G3DSA:2.60.40.730 4 123 3.7E-47 T 22-04-2016 HRM2_RS20700 4213b89d25042713c36e877376f06db5 124 Pfam PF06397 Desulfoferrodoxin, N-terminal domain 3 37 3.9E-12 T 22-04-2016 IPR004462 Desulfoferrodoxin Dfx GO:0005506 HRM2_RS20700 4213b89d25042713c36e877376f06db5 124 TIGRFAM TIGR00319 desulf_FeS4: desulfoferrodoxin FeS4 iron-binding domain 1 34 1.8E-11 T 22-04-2016 IPR004462 Desulfoferrodoxin Dfx GO:0005506 HRM2_RS20700 4213b89d25042713c36e877376f06db5 124 PANTHER PTHR36541 7 122 4.5E-22 T 22-04-2016 HRM2_RS20700 4213b89d25042713c36e877376f06db5 124 PANTHER PTHR36541:SF1 7 122 4.5E-22 T 22-04-2016 HRM2_RS20700 4213b89d25042713c36e877376f06db5 124 Pfam PF01880 Desulfoferrodoxin 43 123 3.9E-20 T 22-04-2016 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 HRM2_RS20700 4213b89d25042713c36e877376f06db5 124 SUPERFAMILY SSF57802 4 37 1.26E-8 T 22-04-2016 HRM2_RS20700 4213b89d25042713c36e877376f06db5 124 TIGRFAM TIGR00332 neela_ferrous: desulfoferrodoxin ferrous iron-binding domain 42 123 9.8E-24 T 22-04-2016 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 TIGRFAM TIGR00484 EF-G: translation elongation factor G 4 687 1.2E-300 T 22-04-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 Gene3D G3DSA:3.30.70.240 593 687 7.2E-29 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 Gene3D G3DSA:3.30.230.10 481 592 1.4E-41 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 Pfam PF00009 Elongation factor Tu GTP binding domain 6 281 9.3E-62 T 22-04-2016 HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 SUPERFAMILY SSF50447 249 274 5.89E-27 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 SUPERFAMILY SSF50447 304 395 5.89E-27 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 Pfam PF03144 Elongation factor Tu domain 2 322 387 8.1E-15 T 22-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 180 2.3E-25 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 PRINTS PR00315 GTP-binding elongation factor signature 79 89 2.2E-15 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 PRINTS PR00315 GTP-binding elongation factor signature 131 140 2.2E-15 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 PRINTS PR00315 GTP-binding elongation factor signature 59 67 2.2E-15 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 PRINTS PR00315 GTP-binding elongation factor signature 10 23 2.2E-15 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 PRINTS PR00315 GTP-binding elongation factor signature 95 106 2.2E-15 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 SUPERFAMILY SSF54980 598 686 2.73E-26 T 22-04-2016 IPR009022 Elongation factor G, III-V domain HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 Pfam PF03764 Elongation factor G, domain IV 476 593 1.4E-40 T 22-04-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 Gene3D G3DSA:3.30.70.870 403 477 1.6E-27 T 22-04-2016 HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 SUPERFAMILY SSF54980 399 477 4.32E-22 T 22-04-2016 IPR009022 Elongation factor G, III-V domain HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 Gene3D G3DSA:3.40.50.300 3 286 1.6E-92 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 22-04-2016 IPR031157 Tr-type G domain, conserved site HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 Hamap MF_00054_B Elongation factor G [fusA]. 4 686 103.776 T 22-04-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 SMART SM00838 595 682 2.4E-43 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 PANTHER PTHR23115:SF162 1 178 0.0 T 22-04-2016 HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 PANTHER PTHR23115:SF162 254 282 0.0 T 22-04-2016 HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 PANTHER PTHR23115:SF162 302 686 0.0 T 22-04-2016 HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 Gene3D G3DSA:2.40.30.10 306 399 1.2E-25 T 22-04-2016 HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 SUPERFAMILY SSF54211 479 594 5.56E-39 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 SUPERFAMILY SSF52540 4 281 4.13E-97 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 Pfam PF14492 Elongation Factor G, domain II 403 475 6.2E-29 T 22-04-2016 IPR009022 Elongation factor G, III-V domain HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 Pfam PF00679 Elongation factor G C-terminus 596 681 5.1E-28 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 SMART SM00889 477 593 2.1E-59 T 22-04-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 PANTHER PTHR23115 1 178 0.0 T 22-04-2016 HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 PANTHER PTHR23115 254 282 0.0 T 22-04-2016 HRM2_RS12365 5b6a837746f6b7913b453160a93dc101 694 PANTHER PTHR23115 302 686 0.0 T 22-04-2016 HRM2_RS19825 d26798ee06120f29f2c8e79444fac8eb 153 PANTHER PTHR31964 1 153 4.5E-21 T 22-04-2016 HRM2_RS19825 d26798ee06120f29f2c8e79444fac8eb 153 SUPERFAMILY SSF52402 3 151 8.29E-28 T 22-04-2016 HRM2_RS19825 d26798ee06120f29f2c8e79444fac8eb 153 Gene3D G3DSA:3.40.50.620 1 152 6.1E-32 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS19825 d26798ee06120f29f2c8e79444fac8eb 153 Pfam PF00582 Universal stress protein family 4 148 3.3E-23 T 22-04-2016 IPR006016 UspA GO:0006950 HRM2_RS19825 d26798ee06120f29f2c8e79444fac8eb 153 PRINTS PR01438 Universal stress protein signature 111 123 9.8E-12 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS19825 d26798ee06120f29f2c8e79444fac8eb 153 PRINTS PR01438 Universal stress protein signature 129 151 9.8E-12 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS19825 d26798ee06120f29f2c8e79444fac8eb 153 PRINTS PR01438 Universal stress protein signature 4 22 9.8E-12 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS09885 0a307f523dc824623552ccf9c60ade0b 426 Gene3D G3DSA:3.40.50.2000 203 392 8.4E-15 T 22-04-2016 HRM2_RS09885 0a307f523dc824623552ccf9c60ade0b 426 SUPERFAMILY SSF53756 11 411 3.08E-50 T 22-04-2016 HRM2_RS09885 0a307f523dc824623552ccf9c60ade0b 426 PANTHER PTHR12526 124 170 2.0E-28 T 22-04-2016 HRM2_RS09885 0a307f523dc824623552ccf9c60ade0b 426 PANTHER PTHR12526 68 101 2.0E-28 T 22-04-2016 HRM2_RS09885 0a307f523dc824623552ccf9c60ade0b 426 PANTHER PTHR12526 187 408 2.0E-28 T 22-04-2016 HRM2_RS09885 0a307f523dc824623552ccf9c60ade0b 426 PANTHER PTHR12526 1 45 2.0E-28 T 22-04-2016 HRM2_RS09885 0a307f523dc824623552ccf9c60ade0b 426 Pfam PF00534 Glycosyl transferases group 1 234 397 2.2E-25 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 HRM2_RS09335 8704009055666423f7eb96a48fac2a17 943 Pfam PF05193 Peptidase M16 inactive domain 694 869 6.6E-23 T 22-04-2016 IPR007863 Peptidase M16, C-terminal HRM2_RS09335 8704009055666423f7eb96a48fac2a17 943 Pfam PF05193 Peptidase M16 inactive domain 218 393 9.5E-16 T 22-04-2016 IPR007863 Peptidase M16, C-terminal HRM2_RS09335 8704009055666423f7eb96a48fac2a17 943 SUPERFAMILY SSF63411 518 740 2.44E-27 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HRM2_RS09335 8704009055666423f7eb96a48fac2a17 943 PANTHER PTHR11851:SF144 43 888 2.3E-102 T 22-04-2016 HRM2_RS09335 8704009055666423f7eb96a48fac2a17 943 SUPERFAMILY SSF63411 38 252 7.13E-39 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HRM2_RS09335 8704009055666423f7eb96a48fac2a17 943 SUPERFAMILY SSF63411 752 930 1.57E-15 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HRM2_RS09335 8704009055666423f7eb96a48fac2a17 943 Pfam PF00675 Insulinase (Peptidase family M16) 54 177 2.4E-24 T 22-04-2016 IPR011765 Peptidase M16, N-terminal HRM2_RS09335 8704009055666423f7eb96a48fac2a17 943 PANTHER PTHR11851 43 888 2.3E-102 T 22-04-2016 HRM2_RS09335 8704009055666423f7eb96a48fac2a17 943 Gene3D G3DSA:3.30.830.10 27 260 5.9E-43 T 22-04-2016 IPR011237 Peptidase M16 domain GO:0046872 HRM2_RS09335 8704009055666423f7eb96a48fac2a17 943 Gene3D G3DSA:3.30.830.10 524 742 2.5E-25 T 22-04-2016 IPR011237 Peptidase M16 domain GO:0046872 HRM2_RS09335 8704009055666423f7eb96a48fac2a17 943 SUPERFAMILY SSF63411 309 478 7.68E-8 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HRM2_RS09335 8704009055666423f7eb96a48fac2a17 943 Gene3D G3DSA:3.30.830.10 339 470 2.8E-4 T 22-04-2016 IPR011237 Peptidase M16 domain GO:0046872 HRM2_RS09335 8704009055666423f7eb96a48fac2a17 943 Gene3D G3DSA:3.30.830.10 798 895 3.9E-8 T 22-04-2016 IPR011237 Peptidase M16 domain GO:0046872 HRM2_RS09335 8704009055666423f7eb96a48fac2a17 943 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 73 96 - T 22-04-2016 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 HRM2_RS12000 c3fb5e0f3f56b004cd767cc3ba3ddcaf 189 Gene3D G3DSA:1.10.357.10 3 177 7.8E-27 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HRM2_RS12000 c3fb5e0f3f56b004cd767cc3ba3ddcaf 189 SUPERFAMILY SSF46689 3 78 1.44E-15 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS12000 c3fb5e0f3f56b004cd767cc3ba3ddcaf 189 SUPERFAMILY SSF48498 78 184 4.36E-7 T 22-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal HRM2_RS12000 c3fb5e0f3f56b004cd767cc3ba3ddcaf 189 PANTHER PTHR30055:SF34 6 139 2.4E-26 T 22-04-2016 HRM2_RS12000 c3fb5e0f3f56b004cd767cc3ba3ddcaf 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 4.5E-12 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS12000 c3fb5e0f3f56b004cd767cc3ba3ddcaf 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 2.2E-5 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS12000 c3fb5e0f3f56b004cd767cc3ba3ddcaf 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 2.2E-5 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS12000 c3fb5e0f3f56b004cd767cc3ba3ddcaf 189 PANTHER PTHR30055 6 139 2.4E-26 T 22-04-2016 HRM2_RS15920 c3b6d0eb9c19c138809c8ad8417e1c79 213 SUPERFAMILY SSF141371 7 107 5.89E-13 T 22-04-2016 HRM2_RS15920 c3b6d0eb9c19c138809c8ad8417e1c79 213 Pfam PF07238 PilZ domain 107 207 4.6E-7 T 22-04-2016 IPR009875 PilZ domain GO:0035438 HRM2_RS15920 c3b6d0eb9c19c138809c8ad8417e1c79 213 Gene3D G3DSA:2.30.110.10 18 107 1.3E-8 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 HRM2_RS15920 c3b6d0eb9c19c138809c8ad8417e1c79 213 Pfam PF12945 Flagellar protein YcgR 17 98 2.0E-13 T 22-04-2016 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal HRM2_RS03965 1541bab7a9053498e50f646bda35f845 731 Pfam PF00425 chorismate binding enzyme 211 465 6.1E-90 T 22-04-2016 IPR015890 Chorismate-utilising enzyme, C-terminal HRM2_RS03965 1541bab7a9053498e50f646bda35f845 731 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 205 468 4.6E-99 T 22-04-2016 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543|UniPathway: UPA00077 HRM2_RS03965 1541bab7a9053498e50f646bda35f845 731 PANTHER PTHR11236 64 483 2.3E-133 T 22-04-2016 HRM2_RS03965 1541bab7a9053498e50f646bda35f845 731 SUPERFAMILY SSF56752 485 730 1.02E-51 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 HRM2_RS03965 1541bab7a9053498e50f646bda35f845 731 Pfam PF04715 Anthranilate synthase component I, N terminal region 26 161 1.2E-21 T 22-04-2016 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 HRM2_RS03965 1541bab7a9053498e50f646bda35f845 731 Pfam PF01063 Amino-transferase class IV 512 730 1.0E-42 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 HRM2_RS03965 1541bab7a9053498e50f646bda35f845 731 Gene3D G3DSA:3.30.470.10 485 581 1.2E-20 T 22-04-2016 HRM2_RS03965 1541bab7a9053498e50f646bda35f845 731 Gene3D G3DSA:3.20.10.10 602 730 3.0E-29 T 22-04-2016 HRM2_RS03965 1541bab7a9053498e50f646bda35f845 731 SUPERFAMILY SSF56322 26 474 3.01E-123 T 22-04-2016 IPR005801 ADC synthase GO:0009058 HRM2_RS03965 1541bab7a9053498e50f646bda35f845 731 Gene3D G3DSA:3.60.120.10 20 475 1.3E-130 T 22-04-2016 IPR005801 ADC synthase GO:0009058 HRM2_RS03965 1541bab7a9053498e50f646bda35f845 731 PRINTS PR00095 Anthranilate synthase component I signature 407 421 1.4E-11 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 HRM2_RS03965 1541bab7a9053498e50f646bda35f845 731 PRINTS PR00095 Anthranilate synthase component I signature 327 340 1.4E-11 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 HRM2_RS03965 1541bab7a9053498e50f646bda35f845 731 PRINTS PR00095 Anthranilate synthase component I signature 422 436 1.4E-11 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 HRM2_RS11005 6e9c854b4aa6b0cb049f2c14b45b8baa 987 SUPERFAMILY SSF103190 177 318 5.89E-8 T 22-04-2016 IPR029151 Periplasmic sensor domain-like HRM2_RS11005 6e9c854b4aa6b0cb049f2c14b45b8baa 987 SUPERFAMILY SSF158472 555 604 1.7E-8 T 22-04-2016 HRM2_RS11005 6e9c854b4aa6b0cb049f2c14b45b8baa 987 PRINTS PR00344 Bacterial sensor protein C-terminal signature 932 942 1.1E-20 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS11005 6e9c854b4aa6b0cb049f2c14b45b8baa 987 PRINTS PR00344 Bacterial sensor protein C-terminal signature 945 963 1.1E-20 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS11005 6e9c854b4aa6b0cb049f2c14b45b8baa 987 PRINTS PR00344 Bacterial sensor protein C-terminal signature 969 982 1.1E-20 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS11005 6e9c854b4aa6b0cb049f2c14b45b8baa 987 PRINTS PR00344 Bacterial sensor protein C-terminal signature 914 928 1.1E-20 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS11005 6e9c854b4aa6b0cb049f2c14b45b8baa 987 Gene3D G3DSA:3.30.565.10 840 982 4.1E-41 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS11005 6e9c854b4aa6b0cb049f2c14b45b8baa 987 SUPERFAMILY SSF58104 573 668 4.18E-5 T 22-04-2016 HRM2_RS11005 6e9c854b4aa6b0cb049f2c14b45b8baa 987 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 878 983 2.0E-24 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS11005 6e9c854b4aa6b0cb049f2c14b45b8baa 987 Gene3D G3DSA:3.30.450.20 177 319 4.5E-18 T 22-04-2016 HRM2_RS11005 6e9c854b4aa6b0cb049f2c14b45b8baa 987 SUPERFAMILY SSF55874 838 983 1.05E-40 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS11005 6e9c854b4aa6b0cb049f2c14b45b8baa 987 SMART SM00387 877 985 3.0E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS11005 6e9c854b4aa6b0cb049f2c14b45b8baa 987 SMART SM00304 553 605 1.1E-9 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS11005 6e9c854b4aa6b0cb049f2c14b45b8baa 987 PANTHER PTHR24423 622 703 9.9E-68 T 22-04-2016 HRM2_RS11005 6e9c854b4aa6b0cb049f2c14b45b8baa 987 PANTHER PTHR24423 811 982 9.9E-68 T 22-04-2016 HRM2_RS11005 6e9c854b4aa6b0cb049f2c14b45b8baa 987 PANTHER PTHR24423 729 739 9.9E-68 T 22-04-2016 HRM2_RS11005 6e9c854b4aa6b0cb049f2c14b45b8baa 987 PANTHER PTHR24423 487 500 9.9E-68 T 22-04-2016 HRM2_RS11005 6e9c854b4aa6b0cb049f2c14b45b8baa 987 PANTHER PTHR24423:SF445 622 703 9.9E-68 T 22-04-2016 HRM2_RS11005 6e9c854b4aa6b0cb049f2c14b45b8baa 987 PANTHER PTHR24423:SF445 811 982 9.9E-68 T 22-04-2016 HRM2_RS11005 6e9c854b4aa6b0cb049f2c14b45b8baa 987 PANTHER PTHR24423:SF445 729 739 9.9E-68 T 22-04-2016 HRM2_RS11005 6e9c854b4aa6b0cb049f2c14b45b8baa 987 PANTHER PTHR24423:SF445 487 500 9.9E-68 T 22-04-2016 HRM2_RS11005 6e9c854b4aa6b0cb049f2c14b45b8baa 987 Pfam PF00672 HAMP domain 535 602 8.9E-12 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS11730 5a9cbb2384dc2370db06f944b10cf209 502 Pfam PF08323 Starch synthase catalytic domain 9 234 8.9E-40 T 22-04-2016 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622|UniPathway: UPA00164 HRM2_RS11730 5a9cbb2384dc2370db06f944b10cf209 502 PANTHER PTHR12526:SF17 32 499 3.6E-66 T 22-04-2016 HRM2_RS11730 5a9cbb2384dc2370db06f944b10cf209 502 Gene3D G3DSA:3.40.50.2000 265 471 3.8E-50 T 22-04-2016 HRM2_RS11730 5a9cbb2384dc2370db06f944b10cf209 502 SUPERFAMILY SSF53756 28 497 4.08E-69 T 22-04-2016 HRM2_RS11730 5a9cbb2384dc2370db06f944b10cf209 502 PANTHER PTHR12526 32 499 3.6E-66 T 22-04-2016 HRM2_RS11730 5a9cbb2384dc2370db06f944b10cf209 502 Pfam PF00534 Glycosyl transferases group 1 303 454 1.2E-11 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 43 158 1.7E-16 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 570 642 2.1E-22 T 22-04-2016 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 Pfam PF01751 Toprim domain 425 519 2.8E-12 T 22-04-2016 IPR006171 Toprim domain HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 ProSitePatterns PS00018 EF-hand calcium-binding domain. 461 473 - T 22-04-2016 IPR018247 EF-Hand 1, calcium-binding site HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 Pfam PF00204 DNA gyrase B 230 396 5.8E-41 T 22-04-2016 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 PANTHER PTHR10169:SF45 17 651 0.0 T 22-04-2016 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 SMART SM00387 39 185 5.1E-14 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 PRINTS PR00418 DNA topoisomerase II family signature 574 590 1.3E-57 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 PRINTS PR00418 DNA topoisomerase II family signature 278 291 1.3E-57 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 PRINTS PR00418 DNA topoisomerase II family signature 509 526 1.3E-57 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 PRINTS PR00418 DNA topoisomerase II family signature 426 440 1.3E-57 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 PRINTS PR00418 DNA topoisomerase II family signature 491 507 1.3E-57 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 PRINTS PR00418 DNA topoisomerase II family signature 121 135 1.3E-57 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 PRINTS PR00418 DNA topoisomerase II family signature 78 91 1.3E-57 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 PRINTS PR00418 DNA topoisomerase II family signature 529 541 1.3E-57 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 PRINTS PR00418 DNA topoisomerase II family signature 43 58 1.3E-57 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 SUPERFAMILY SSF54211 230 394 3.22E-43 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 14 650 45.374 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 PANTHER PTHR10169 17 651 0.0 T 22-04-2016 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 TIGRFAM TIGR01055 parE_Gneg: DNA topoisomerase IV, B subunit 15 647 2.3E-279 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 Gene3D G3DSA:3.30.230.10 230 402 2.7E-47 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 Gene3D G3DSA:3.30.565.10 17 227 4.6E-70 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 Gene3D G3DSA:3.40.50.670 410 608 1.4E-74 T 22-04-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 PRINTS PR01098 Topoisomerase IV subunit B signature 250 273 4.1E-79 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 PRINTS PR01098 Topoisomerase IV subunit B signature 374 399 4.1E-79 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 PRINTS PR01098 Topoisomerase IV subunit B signature 38 51 4.1E-79 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 PRINTS PR01098 Topoisomerase IV subunit B signature 481 493 4.1E-79 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 PRINTS PR01098 Topoisomerase IV subunit B signature 161 176 4.1E-79 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 PRINTS PR01098 Topoisomerase IV subunit B signature 460 481 4.1E-79 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 PRINTS PR01098 Topoisomerase IV subunit B signature 306 322 4.1E-79 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 PRINTS PR01098 Topoisomerase IV subunit B signature 204 225 4.1E-79 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 PRINTS PR01098 Topoisomerase IV subunit B signature 549 571 4.1E-79 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 PRINTS PR01098 Topoisomerase IV subunit B signature 350 373 4.1E-79 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 PRINTS PR01098 Topoisomerase IV subunit B signature 323 338 4.1E-79 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 PRINTS PR01098 Topoisomerase IV subunit B signature 186 203 4.1E-79 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 PRINTS PR01098 Topoisomerase IV subunit B signature 515 531 4.1E-79 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 PRINTS PR01098 Topoisomerase IV subunit B signature 147 161 4.1E-79 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 SUPERFAMILY SSF56719 400 643 7.59E-75 T 22-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 ProSitePatterns PS00177 DNA topoisomerase II signature. 428 436 - T 22-04-2016 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 SMART SM00433 46 646 6.0E-197 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS11605 a11f2aeb61f4388b307bdcb3a1dc4b68 651 SUPERFAMILY SSF55874 17 227 1.2E-58 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS02060 e2ae045624a4e8007a31b33f1c8bd14a 304 SUPERFAMILY SSF48403 52 268 3.2E-37 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain HRM2_RS02060 e2ae045624a4e8007a31b33f1c8bd14a 304 PANTHER PTHR24198 49 283 3.7E-35 T 22-04-2016 HRM2_RS02060 e2ae045624a4e8007a31b33f1c8bd14a 304 SMART SM00248 145 174 420.0 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 HRM2_RS02060 e2ae045624a4e8007a31b33f1c8bd14a 304 SMART SM00248 220 249 0.0063 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 HRM2_RS02060 e2ae045624a4e8007a31b33f1c8bd14a 304 SMART SM00248 80 109 0.0035 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 HRM2_RS02060 e2ae045624a4e8007a31b33f1c8bd14a 304 SMART SM00248 187 216 1600.0 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 HRM2_RS02060 e2ae045624a4e8007a31b33f1c8bd14a 304 SMART SM00248 113 142 300.0 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 HRM2_RS02060 e2ae045624a4e8007a31b33f1c8bd14a 304 SMART SM00248 253 282 1100.0 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 HRM2_RS02060 e2ae045624a4e8007a31b33f1c8bd14a 304 Pfam PF12796 Ankyrin repeats (3 copies) 202 268 5.7E-8 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain HRM2_RS02060 e2ae045624a4e8007a31b33f1c8bd14a 304 Pfam PF12796 Ankyrin repeats (3 copies) 53 108 3.7E-6 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain HRM2_RS02060 e2ae045624a4e8007a31b33f1c8bd14a 304 Gene3D G3DSA:1.25.40.20 52 269 3.4E-40 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain HRM2_RS18420 33c0423db3b3f6363cf337a89922b73c 455 Pfam PF02954 Bacterial regulatory protein, Fis family 409 449 1.5E-13 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS18420 33c0423db3b3f6363cf337a89922b73c 455 SUPERFAMILY SSF52540 141 382 2.03E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18420 33c0423db3b3f6363cf337a89922b73c 455 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 415 432 3.0E-8 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS18420 33c0423db3b3f6363cf337a89922b73c 455 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 432 452 3.0E-8 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS18420 33c0423db3b3f6363cf337a89922b73c 455 Gene3D G3DSA:1.10.8.60 314 367 6.8E-15 T 22-04-2016 HRM2_RS18420 33c0423db3b3f6363cf337a89922b73c 455 Pfam PF00072 Response regulator receiver domain 7 111 7.8E-16 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18420 33c0423db3b3f6363cf337a89922b73c 455 Gene3D G3DSA:1.10.10.60 368 450 1.4E-17 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS18420 33c0423db3b3f6363cf337a89922b73c 455 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 165 178 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS18420 33c0423db3b3f6363cf337a89922b73c 455 SMART SM00448 4 114 1.2E-12 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18420 33c0423db3b3f6363cf337a89922b73c 455 Gene3D G3DSA:3.40.50.300 140 313 9.9E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18420 33c0423db3b3f6363cf337a89922b73c 455 PANTHER PTHR32071 1 449 1.8E-169 T 22-04-2016 HRM2_RS18420 33c0423db3b3f6363cf337a89922b73c 455 SUPERFAMILY SSF52172 5 185 1.29E-29 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS18420 33c0423db3b3f6363cf337a89922b73c 455 Pfam PF00158 Sigma-54 interaction domain 141 307 1.5E-70 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS18420 33c0423db3b3f6363cf337a89922b73c 455 SUPERFAMILY SSF46689 355 449 2.51E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS18420 33c0423db3b3f6363cf337a89922b73c 455 Gene3D G3DSA:3.40.50.2300 3 126 1.4E-21 T 22-04-2016 HRM2_RS18420 33c0423db3b3f6363cf337a89922b73c 455 SMART SM00382 161 304 9.0E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS12415 1a94581b6836fa78f79036e682b3e267 495 SUPERFAMILY SSF53383 54 493 2.25E-100 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS12415 1a94581b6836fa78f79036e682b3e267 495 Pfam PF02347 Glycine cleavage system P-protein 115 317 3.3E-10 T 22-04-2016 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 HRM2_RS12415 1a94581b6836fa78f79036e682b3e267 495 PANTHER PTHR11773 24 493 4.6E-234 T 22-04-2016 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 HRM2_RS12415 1a94581b6836fa78f79036e682b3e267 495 Gene3D G3DSA:3.40.640.10 86 316 3.5E-29 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS17835 201f5445e1581b6cfcb46035ff545b84 131 SUPERFAMILY SSF56047 3 131 2.35E-47 T 22-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17835 201f5445e1581b6cfcb46035ff545b84 131 Gene3D G3DSA:3.30.1490.10 75 131 1.2E-27 T 22-04-2016 HRM2_RS17835 201f5445e1581b6cfcb46035ff545b84 131 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 131 31.623 T 22-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17835 201f5445e1581b6cfcb46035ff545b84 131 PANTHER PTHR11758 1 131 2.8E-55 T 22-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17835 201f5445e1581b6cfcb46035ff545b84 131 ProSitePatterns PS00053 Ribosomal protein S8 signature. 101 118 - T 22-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17835 201f5445e1581b6cfcb46035ff545b84 131 Gene3D G3DSA:3.30.1370.30 3 72 4.9E-26 T 22-04-2016 HRM2_RS17835 201f5445e1581b6cfcb46035ff545b84 131 Pfam PF00410 Ribosomal protein S8 5 131 1.4E-49 T 22-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 HRM2_RS04975 76c1277502123767350df990063a8fba 363 PANTHER PTHR22893:SF14 2 363 4.0E-155 T 22-04-2016 HRM2_RS04975 76c1277502123767350df990063a8fba 363 Gene3D G3DSA:3.20.20.70 6 362 4.0E-121 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS04975 76c1277502123767350df990063a8fba 363 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 16 336 1.9E-81 T 22-04-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 HRM2_RS04975 76c1277502123767350df990063a8fba 363 PANTHER PTHR22893 2 363 4.0E-155 T 22-04-2016 HRM2_RS04975 76c1277502123767350df990063a8fba 363 SUPERFAMILY SSF51395 6 362 1.47E-110 T 22-04-2016 HRM2_RS13370 466320f345f28aaa925672b6ec9b6eae 305 Pfam PF02911 Formyl transferase, C-terminal domain 199 295 5.7E-28 T 22-04-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HRM2_RS13370 466320f345f28aaa925672b6ec9b6eae 305 Gene3D G3DSA:3.40.50.170 1 199 1.2E-63 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HRM2_RS13370 466320f345f28aaa925672b6ec9b6eae 305 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 295 5.6E-85 T 22-04-2016 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HRM2_RS13370 466320f345f28aaa925672b6ec9b6eae 305 SUPERFAMILY SSF50486 199 303 1.4E-31 T 22-04-2016 IPR011034 Formyl transferase, C-terminal-like GO:0003824 HRM2_RS13370 466320f345f28aaa925672b6ec9b6eae 305 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 127 150 - T 22-04-2016 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HRM2_RS13370 466320f345f28aaa925672b6ec9b6eae 305 Gene3D G3DSA:3.10.25.10 201 303 1.7E-33 T 22-04-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HRM2_RS13370 466320f345f28aaa925672b6ec9b6eae 305 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 298 32.751 T 22-04-2016 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HRM2_RS13370 466320f345f28aaa925672b6ec9b6eae 305 SUPERFAMILY SSF53328 1 201 1.57E-60 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HRM2_RS13370 466320f345f28aaa925672b6ec9b6eae 305 PANTHER PTHR11138 1 294 1.1E-100 T 22-04-2016 HRM2_RS13370 466320f345f28aaa925672b6ec9b6eae 305 Pfam PF00551 Formyl transferase 13 174 6.3E-35 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HRM2_RS08275 f156f6e5caf55edcb660465780b10869 737 Gene3D G3DSA:1.10.8.190 1 111 7.8E-30 T 22-04-2016 HRM2_RS08275 f156f6e5caf55edcb660465780b10869 737 SUPERFAMILY SSF56821 6 734 4.58E-243 T 22-04-2016 IPR011254 Prismane-like GO:0003824|GO:0016491|GO:0055114 HRM2_RS08275 f156f6e5caf55edcb660465780b10869 737 Pfam PF03598 CO dehydrogenase/acetyl-CoA synthase complex beta subunit 328 482 3.6E-67 T 22-04-2016 IPR004461 CO dehydrogenase/acetyl-CoA synthase complex beta subunit GO:0006084|GO:0018492 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|KEGG: 00720+2.3.1.169|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726 HRM2_RS08275 f156f6e5caf55edcb660465780b10869 737 TIGRFAM TIGR00316 cdhC: CO dehydrogenase/CO-methylating acetyl-CoA synthase complex, beta subunit 326 730 4.7E-131 T 22-04-2016 IPR004461 CO dehydrogenase/acetyl-CoA synthase complex beta subunit GO:0006084|GO:0018492 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|KEGG: 00720+2.3.1.169|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726 HRM2_RS08275 f156f6e5caf55edcb660465780b10869 737 PANTHER PTHR42281 17 108 2.8E-184 T 22-04-2016 HRM2_RS08275 f156f6e5caf55edcb660465780b10869 737 PANTHER PTHR42281 126 736 2.8E-184 T 22-04-2016 HRM2_RS08275 f156f6e5caf55edcb660465780b10869 737 Gene3D G3DSA:3.30.1650.10 326 500 1.7E-69 T 22-04-2016 HRM2_RS08275 f156f6e5caf55edcb660465780b10869 737 Gene3D G3DSA:3.40.1470.10 607 734 1.6E-49 T 22-04-2016 HRM2_RS08275 f156f6e5caf55edcb660465780b10869 737 Gene3D G3DSA:3.40.50.2030 125 319 8.7E-76 T 22-04-2016 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS08275 f156f6e5caf55edcb660465780b10869 737 Gene3D G3DSA:3.40.970.20 502 592 5.5E-43 T 22-04-2016 HRM2_RS09255 92fc7a05ee4e9f95deb7d80b89c2e378 469 PANTHER PTHR30050 129 466 2.8E-121 T 22-04-2016 HRM2_RS09255 92fc7a05ee4e9f95deb7d80b89c2e378 469 PANTHER PTHR30050 1 102 2.8E-121 T 22-04-2016 HRM2_RS09255 92fc7a05ee4e9f95deb7d80b89c2e378 469 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 5 463 1.1E-115 T 22-04-2016 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 HRM2_RS09255 92fc7a05ee4e9f95deb7d80b89c2e378 469 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 196 210 4.0E-21 T 22-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like HRM2_RS09255 92fc7a05ee4e9f95deb7d80b89c2e378 469 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 164 184 4.0E-21 T 22-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like HRM2_RS09255 92fc7a05ee4e9f95deb7d80b89c2e378 469 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 229 243 4.0E-21 T 22-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like HRM2_RS09255 92fc7a05ee4e9f95deb7d80b89c2e378 469 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 423 442 4.0E-21 T 22-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like HRM2_RS09255 92fc7a05ee4e9f95deb7d80b89c2e378 469 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 263 290 4.0E-21 T 22-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like HRM2_RS09255 92fc7a05ee4e9f95deb7d80b89c2e378 469 SMART SM00760 374 442 1.1E-22 T 22-04-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 HRM2_RS09255 92fc7a05ee4e9f95deb7d80b89c2e378 469 Pfam PF11638 DnaA N-terminal domain 3 63 6.7E-13 T 22-04-2016 IPR024633 DnaA N-terminal domain HRM2_RS09255 92fc7a05ee4e9f95deb7d80b89c2e378 469 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 376 442 7.6E-21 T 22-04-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 HRM2_RS09255 92fc7a05ee4e9f95deb7d80b89c2e378 469 SUPERFAMILY SSF48295 367 465 3.14E-25 T 22-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 HRM2_RS09255 92fc7a05ee4e9f95deb7d80b89c2e378 469 Gene3D G3DSA:3.40.50.300 131 296 2.1E-34 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09255 92fc7a05ee4e9f95deb7d80b89c2e378 469 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 2 464 24.0 T 22-04-2016 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 HRM2_RS09255 92fc7a05ee4e9f95deb7d80b89c2e378 469 Gene3D G3DSA:1.10.8.60 299 366 2.8E-17 T 22-04-2016 HRM2_RS09255 92fc7a05ee4e9f95deb7d80b89c2e378 469 Gene3D G3DSA:1.10.1750.10 367 465 1.2E-26 T 22-04-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 HRM2_RS09255 92fc7a05ee4e9f95deb7d80b89c2e378 469 PANTHER PTHR30050:SF2 129 466 2.8E-121 T 22-04-2016 HRM2_RS09255 92fc7a05ee4e9f95deb7d80b89c2e378 469 PANTHER PTHR30050:SF2 1 102 2.8E-121 T 22-04-2016 HRM2_RS09255 92fc7a05ee4e9f95deb7d80b89c2e378 469 SUPERFAMILY SSF52540 133 338 4.93E-27 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09255 92fc7a05ee4e9f95deb7d80b89c2e378 469 Pfam PF00308 Bacterial dnaA protein 131 343 1.4E-60 T 22-04-2016 IPR013317 Chromosomal replication initiator protein DnaA HRM2_RS06115 19975cdb0f49e1f273d6972a664637a0 309 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 2.4E-37 T 22-04-2016 HRM2_RS06115 19975cdb0f49e1f273d6972a664637a0 309 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 2.4E-37 T 22-04-2016 HRM2_RS06115 19975cdb0f49e1f273d6972a664637a0 309 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 2.4E-37 T 22-04-2016 HRM2_RS06115 19975cdb0f49e1f273d6972a664637a0 309 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 2.4E-37 T 22-04-2016 HRM2_RS06115 19975cdb0f49e1f273d6972a664637a0 309 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 2.4E-37 T 22-04-2016 HRM2_RS06115 19975cdb0f49e1f273d6972a664637a0 309 SUPERFAMILY SSF51905 1 300 4.88E-53 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS06115 19975cdb0f49e1f273d6972a664637a0 309 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 291 4.5E-52 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS06115 19975cdb0f49e1f273d6972a664637a0 309 PANTHER PTHR22912:SF48 1 308 9.9E-131 T 22-04-2016 HRM2_RS06115 19975cdb0f49e1f273d6972a664637a0 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 268 286 3.3E-64 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HRM2_RS06115 19975cdb0f49e1f273d6972a664637a0 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 196 212 3.3E-64 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HRM2_RS06115 19975cdb0f49e1f273d6972a664637a0 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 234 255 3.3E-64 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HRM2_RS06115 19975cdb0f49e1f273d6972a664637a0 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 42 57 3.3E-64 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HRM2_RS06115 19975cdb0f49e1f273d6972a664637a0 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 108 116 3.3E-64 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HRM2_RS06115 19975cdb0f49e1f273d6972a664637a0 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 63 73 3.3E-64 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HRM2_RS06115 19975cdb0f49e1f273d6972a664637a0 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 3.3E-64 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HRM2_RS06115 19975cdb0f49e1f273d6972a664637a0 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 3.3E-64 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HRM2_RS06115 19975cdb0f49e1f273d6972a664637a0 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 3.3E-64 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HRM2_RS06115 19975cdb0f49e1f273d6972a664637a0 309 PANTHER PTHR22912 1 308 9.9E-131 T 22-04-2016 HRM2_RS06115 19975cdb0f49e1f273d6972a664637a0 309 Gene3D G3DSA:3.50.50.60 124 240 7.9E-30 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS06115 19975cdb0f49e1f273d6972a664637a0 309 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 8 305 3.7E-114 T 22-04-2016 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 HRM2_RS06115 19975cdb0f49e1f273d6972a664637a0 309 Gene3D G3DSA:3.50.50.60 6 122 7.2E-43 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS06115 19975cdb0f49e1f273d6972a664637a0 309 Gene3D G3DSA:3.50.50.60 241 305 7.2E-43 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS20905 7bbde33755c27e6d32258aa78d4709d0 347 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 307 42.065 T 22-04-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 HRM2_RS20905 7bbde33755c27e6d32258aa78d4709d0 347 PIRSF PIRSF001365 1 313 1.7E-71 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 HRM2_RS20905 7bbde33755c27e6d32258aa78d4709d0 347 PANTHER PTHR12128:SF34 1 323 4.4E-78 T 22-04-2016 HRM2_RS20905 7bbde33755c27e6d32258aa78d4709d0 347 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 5 295 2.8E-65 T 22-04-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 HRM2_RS20905 7bbde33755c27e6d32258aa78d4709d0 347 Pfam PF00701 Dihydrodipicolinate synthetase family 3 297 2.1E-68 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 HRM2_RS20905 7bbde33755c27e6d32258aa78d4709d0 347 Gene3D G3DSA:3.20.20.70 3 308 9.7E-85 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS20905 7bbde33755c27e6d32258aa78d4709d0 347 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 38 55 - T 22-04-2016 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 HRM2_RS20905 7bbde33755c27e6d32258aa78d4709d0 347 PANTHER PTHR12128 1 323 4.4E-78 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 HRM2_RS20905 7bbde33755c27e6d32258aa78d4709d0 347 SMART SM01130 1 309 5.0E-78 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 HRM2_RS20905 7bbde33755c27e6d32258aa78d4709d0 347 SUPERFAMILY SSF51569 2 307 1.57E-73 T 22-04-2016 HRM2_RS20905 7bbde33755c27e6d32258aa78d4709d0 347 PRINTS PR00146 Dihydrodipicolinate synthase signature 71 89 6.4E-18 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 HRM2_RS20905 7bbde33755c27e6d32258aa78d4709d0 347 PRINTS PR00146 Dihydrodipicolinate synthase signature 35 56 6.4E-18 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 HRM2_RS20905 7bbde33755c27e6d32258aa78d4709d0 347 PRINTS PR00146 Dihydrodipicolinate synthase signature 130 147 6.4E-18 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 HRM2_RS02345 b8cbb1ef12043c6e5065346169e4e01b 354 SUPERFAMILY SSF55073 184 337 4.63E-46 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS02345 b8cbb1ef12043c6e5065346169e4e01b 354 Pfam PF00990 Diguanylate cyclase, GGDEF domain 179 335 5.6E-47 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS02345 b8cbb1ef12043c6e5065346169e4e01b 354 SMART SM00267 168 339 5.4E-58 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS02345 b8cbb1ef12043c6e5065346169e4e01b 354 PANTHER PTHR10799 212 337 2.0E-26 T 22-04-2016 HRM2_RS02345 b8cbb1ef12043c6e5065346169e4e01b 354 PANTHER PTHR10799 25 93 2.0E-26 T 22-04-2016 HRM2_RS02345 b8cbb1ef12043c6e5065346169e4e01b 354 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 178 336 3.5E-53 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS02345 b8cbb1ef12043c6e5065346169e4e01b 354 Gene3D G3DSA:3.30.70.270 181 337 9.1E-53 T 22-04-2016 HRM2_RS02345 b8cbb1ef12043c6e5065346169e4e01b 354 PANTHER PTHR10799:SF750 212 337 2.0E-26 T 22-04-2016 HRM2_RS02345 b8cbb1ef12043c6e5065346169e4e01b 354 PANTHER PTHR10799:SF750 25 93 2.0E-26 T 22-04-2016 HRM2_RS03400 f31873b00dcb21d4fda22a739ee2a2aa 347 Pfam PF13478 XdhC Rossmann domain 197 339 5.7E-42 T 22-04-2016 IPR027051 XdhC Rossmann domain HRM2_RS03400 f31873b00dcb21d4fda22a739ee2a2aa 347 Pfam PF02625 XdhC and CoxI family 12 71 4.2E-17 T 22-04-2016 IPR003777 XdhC- CoxI HRM2_RS03400 f31873b00dcb21d4fda22a739ee2a2aa 347 SUPERFAMILY SSF51984 196 283 5.49E-5 T 22-04-2016 HRM2_RS03400 f31873b00dcb21d4fda22a739ee2a2aa 347 PANTHER PTHR30388 162 347 1.0E-69 T 22-04-2016 HRM2_RS03400 f31873b00dcb21d4fda22a739ee2a2aa 347 PANTHER PTHR30388 1 125 1.0E-69 T 22-04-2016 HRM2_RS03400 f31873b00dcb21d4fda22a739ee2a2aa 347 Gene3D G3DSA:3.40.50.720 198 276 7.4E-4 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS18445 bbde027d0e2d3f00ddb4e4bb9212bfee 112 SUPERFAMILY SSF141371 8 112 8.04E-20 T 22-04-2016 HRM2_RS18445 bbde027d0e2d3f00ddb4e4bb9212bfee 112 Pfam PF07238 PilZ domain 8 106 3.2E-12 T 22-04-2016 IPR009875 PilZ domain GO:0035438 HRM2_RS18445 bbde027d0e2d3f00ddb4e4bb9212bfee 112 Gene3D G3DSA:2.40.10.220 8 112 5.0E-16 T 22-04-2016 HRM2_RS07150 41436210439e4a25fec94c7e93184c55 171 Pfam PF02662 Methyl-viologen-reducing hydrogenase, delta subunit 22 143 1.1E-31 T 22-04-2016 IPR003813 Methyl-viologen-reducing hydrogenase, delta subunit GO:0015948|GO:0055114 HRM2_RS10655 65be9a8c744f5879bf5f693130586e09 395 SUPERFAMILY SSF51556 56 350 2.48E-61 T 22-04-2016 IPR032466 Metal-dependent hydrolase HRM2_RS10655 65be9a8c744f5879bf5f693130586e09 395 PANTHER PTHR11647:SF72 2 125 9.7E-31 T 22-04-2016 HRM2_RS10655 65be9a8c744f5879bf5f693130586e09 395 SUPERFAMILY SSF51338 360 388 2.59E-14 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS10655 65be9a8c744f5879bf5f693130586e09 395 SUPERFAMILY SSF51338 2 57 2.59E-14 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS10655 65be9a8c744f5879bf5f693130586e09 395 Gene3D G3DSA:2.30.40.10 335 387 6.3E-6 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS10655 65be9a8c744f5879bf5f693130586e09 395 Gene3D G3DSA:2.30.40.10 1 63 3.5E-15 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS10655 65be9a8c744f5879bf5f693130586e09 395 Pfam PF01979 Amidohydrolase family 52 380 5.6E-12 T 22-04-2016 IPR006680 Amidohydrolase-related GO:0016787 HRM2_RS10655 65be9a8c744f5879bf5f693130586e09 395 PANTHER PTHR11647 2 125 9.7E-31 T 22-04-2016 HRM2_RS10655 65be9a8c744f5879bf5f693130586e09 395 Gene3D G3DSA:3.20.20.140 64 334 1.1E-97 T 22-04-2016 HRM2_RS10655 65be9a8c744f5879bf5f693130586e09 395 PIRSF PIRSF001238 1 395 2.0E-124 T 22-04-2016 IPR010229 Peptidase M38, beta-aspartyl dipeptidase GO:0008798 HRM2_RS10655 65be9a8c744f5879bf5f693130586e09 395 TIGRFAM TIGR01975 isoAsp_dipep: beta-aspartyl peptidase 2 395 2.8E-110 T 22-04-2016 IPR010229 Peptidase M38, beta-aspartyl dipeptidase GO:0008798 HRM2_RS20820 5b23b207f26a9518f89714edbf35d29c 407 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 178 394 5.6E-78 T 22-04-2016 HRM2_RS20820 5b23b207f26a9518f89714edbf35d29c 407 Gene3D G3DSA:3.30.70.260 2 83 1.4E-15 T 22-04-2016 HRM2_RS20820 5b23b207f26a9518f89714edbf35d29c 407 Gene3D G3DSA:3.30.70.260 112 191 9.0E-6 T 22-04-2016 HRM2_RS20820 5b23b207f26a9518f89714edbf35d29c 407 PANTHER PTHR10000:SF7 188 401 4.7E-83 T 22-04-2016 HRM2_RS20820 5b23b207f26a9518f89714edbf35d29c 407 Gene3D G3DSA:3.40.50.1000 254 382 1.4E-36 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS20820 5b23b207f26a9518f89714edbf35d29c 407 PANTHER PTHR10000 188 401 4.7E-83 T 22-04-2016 HRM2_RS20820 5b23b207f26a9518f89714edbf35d29c 407 Pfam PF13740 ACT domain 4 79 6.8E-22 T 22-04-2016 HRM2_RS20820 5b23b207f26a9518f89714edbf35d29c 407 SUPERFAMILY SSF56784 187 395 1.71E-50 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS20820 5b23b207f26a9518f89714edbf35d29c 407 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 192 362 5.2E-30 T 22-04-2016 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 HRM2_RS20820 5b23b207f26a9518f89714edbf35d29c 407 Gene3D G3DSA:1.10.150.210 202 253 1.7E-25 T 22-04-2016 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|UniPathway: UPA00135 HRM2_RS20820 5b23b207f26a9518f89714edbf35d29c 407 SUPERFAMILY SSF55021 4 81 2.08E-11 T 22-04-2016 HRM2_RS20820 5b23b207f26a9518f89714edbf35d29c 407 Pfam PF12710 haloacid dehalogenase-like hydrolase 193 359 2.5E-18 T 22-04-2016 HRM2_RS17070 66eeedbe926b3281e68de5ec272287b2 397 PANTHER PTHR23501 9 365 5.2E-19 T 22-04-2016 HRM2_RS17070 66eeedbe926b3281e68de5ec272287b2 397 Pfam PF07690 Major Facilitator Superfamily 26 275 2.2E-23 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS17070 66eeedbe926b3281e68de5ec272287b2 397 Gene3D G3DSA:1.20.1250.20 19 191 2.2E-21 T 22-04-2016 HRM2_RS17070 66eeedbe926b3281e68de5ec272287b2 397 Gene3D G3DSA:1.20.1250.20 217 393 7.0E-18 T 22-04-2016 HRM2_RS17070 66eeedbe926b3281e68de5ec272287b2 397 SUPERFAMILY SSF103473 7 393 1.15E-54 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS10665 2aef9c85e6a9296eb3d55de3b9ac7452 506 SUPERFAMILY SSF53850 25 502 3.26E-130 T 22-04-2016 HRM2_RS10665 2aef9c85e6a9296eb3d55de3b9ac7452 506 Gene3D G3DSA:3.10.105.10 273 474 7.8E-52 T 22-04-2016 HRM2_RS10665 2aef9c85e6a9296eb3d55de3b9ac7452 506 PANTHER PTHR30290 8 504 2.7E-125 T 22-04-2016 HRM2_RS10665 2aef9c85e6a9296eb3d55de3b9ac7452 506 Gene3D G3DSA:3.40.190.10 124 272 6.1E-49 T 22-04-2016 HRM2_RS10665 2aef9c85e6a9296eb3d55de3b9ac7452 506 PIRSF PIRSF002741 15 506 4.1E-103 T 22-04-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 HRM2_RS10665 2aef9c85e6a9296eb3d55de3b9ac7452 506 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 66 418 3.9E-89 T 22-04-2016 IPR000914 Solute-binding protein family 5 domain HRM2_RS10665 2aef9c85e6a9296eb3d55de3b9ac7452 506 PANTHER PTHR30290:SF32 8 504 2.7E-125 T 22-04-2016 HRM2_RS10390 ae184acda425cfd42d9b341e234fe81b 563 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 392 538 3.0E-50 T 22-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HRM2_RS10390 ae184acda425cfd42d9b341e234fe81b 563 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 194 327 1.9E-44 T 22-04-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 HRM2_RS10390 ae184acda425cfd42d9b341e234fe81b 563 SUPERFAMILY SSF52518 369 561 1.02E-67 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS10390 ae184acda425cfd42d9b341e234fe81b 563 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 428 447 - T 22-04-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 HRM2_RS10390 ae184acda425cfd42d9b341e234fe81b 563 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 3 561 5.2E-252 T 22-04-2016 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HRM2_RS10390 ae184acda425cfd42d9b341e234fe81b 563 Gene3D G3DSA:3.40.50.970 1 179 6.4E-74 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS10390 ae184acda425cfd42d9b341e234fe81b 563 Gene3D G3DSA:3.40.50.1220 188 351 5.0E-64 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HRM2_RS10390 ae184acda425cfd42d9b341e234fe81b 563 Gene3D G3DSA:3.40.50.970 352 555 1.4E-76 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS10390 ae184acda425cfd42d9b341e234fe81b 563 PANTHER PTHR18968 1 562 0.0 T 22-04-2016 HRM2_RS10390 ae184acda425cfd42d9b341e234fe81b 563 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 170 3.6E-57 T 22-04-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 HRM2_RS10390 ae184acda425cfd42d9b341e234fe81b 563 PANTHER PTHR18968:SF116 1 562 0.0 T 22-04-2016 HRM2_RS10390 ae184acda425cfd42d9b341e234fe81b 563 SUPERFAMILY SSF52467 185 359 8.91E-63 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HRM2_RS10390 ae184acda425cfd42d9b341e234fe81b 563 SUPERFAMILY SSF52518 1 184 2.42E-64 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS10210 c1e941e9be16ac2ea17e26381ff871c4 878 Pfam PF02384 N-6 DNA Methylase 331 411 1.8E-4 T 22-04-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 HRM2_RS10210 c1e941e9be16ac2ea17e26381ff871c4 878 PANTHER PTHR33841 3 874 1.1E-171 T 22-04-2016 HRM2_RS10210 c1e941e9be16ac2ea17e26381ff871c4 878 Gene3D G3DSA:3.40.50.150 331 537 8.4E-20 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS10210 c1e941e9be16ac2ea17e26381ff871c4 878 PANTHER PTHR33841:SF3 3 874 1.1E-171 T 22-04-2016 HRM2_RS10210 c1e941e9be16ac2ea17e26381ff871c4 878 SUPERFAMILY SSF53335 165 574 3.51E-52 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS07405 f34cce0df63cb77c830464b89b494a4f 148 Gene3D G3DSA:1.10.10.10 6 140 7.7E-32 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS07405 f34cce0df63cb77c830464b89b494a4f 148 SUPERFAMILY SSF46785 7 142 1.46E-29 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS07405 f34cce0df63cb77c830464b89b494a4f 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 1.3E-5 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS07405 f34cce0df63cb77c830464b89b494a4f 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 1.3E-5 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS07405 f34cce0df63cb77c830464b89b494a4f 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 1.3E-5 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS07405 f34cce0df63cb77c830464b89b494a4f 148 PANTHER PTHR33164 10 141 2.9E-22 T 22-04-2016 HRM2_RS07405 f34cce0df63cb77c830464b89b494a4f 148 SMART SM00347 27 127 2.4E-16 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS07405 f34cce0df63cb77c830464b89b494a4f 148 Pfam PF01047 MarR family 38 91 3.3E-13 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS02295 bacadf15dc35a8fe2f741b143c780f9b 482 Pfam PF13184 NusA-like KH domain 230 298 4.6E-28 T 22-04-2016 IPR025249 KH domain, NusA-like GO:0003723 HRM2_RS02295 bacadf15dc35a8fe2f741b143c780f9b 482 Gene3D G3DSA:3.30.300.20 199 277 1.3E-34 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta HRM2_RS02295 bacadf15dc35a8fe2f741b143c780f9b 482 Pfam PF14520 Helix-hairpin-helix domain 353 408 3.9E-6 T 22-04-2016 HRM2_RS02295 bacadf15dc35a8fe2f741b143c780f9b 482 Gene3D G3DSA:3.30.1480.10 5 125 1.5E-38 T 22-04-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 HRM2_RS02295 bacadf15dc35a8fe2f741b143c780f9b 482 SMART SM00316 134 200 1.8E-9 T 22-04-2016 IPR022967 RNA-binding domain, S1 HRM2_RS02295 bacadf15dc35a8fe2f741b143c780f9b 482 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 3 437 29.261 T 22-04-2016 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 HRM2_RS02295 bacadf15dc35a8fe2f741b143c780f9b 482 Gene3D G3DSA:2.40.50.140 130 198 8.3E-28 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS02295 bacadf15dc35a8fe2f741b143c780f9b 482 PANTHER PTHR22648 2 444 8.8E-153 T 22-04-2016 HRM2_RS02295 bacadf15dc35a8fe2f741b143c780f9b 482 SUPERFAMILY SSF50249 133 199 5.83E-18 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS02295 bacadf15dc35a8fe2f741b143c780f9b 482 SUPERFAMILY SSF54814 279 343 1.05E-16 T 22-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 HRM2_RS02295 bacadf15dc35a8fe2f741b143c780f9b 482 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 8 342 5.8E-126 T 22-04-2016 IPR010213 Transcription termination factor NusA GO:0003723 HRM2_RS02295 bacadf15dc35a8fe2f741b143c780f9b 482 Pfam PF08529 NusA N-terminal domain 6 125 4.9E-33 T 22-04-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 HRM2_RS02295 bacadf15dc35a8fe2f741b143c780f9b 482 Pfam PF00575 S1 RNA binding domain 133 193 1.0E-7 T 22-04-2016 IPR003029 S1 domain GO:0003676 HRM2_RS02295 bacadf15dc35a8fe2f741b143c780f9b 482 Gene3D G3DSA:3.30.300.20 279 345 2.5E-29 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta HRM2_RS02295 bacadf15dc35a8fe2f741b143c780f9b 482 Gene3D G3DSA:1.10.150.20 346 410 9.3E-14 T 22-04-2016 HRM2_RS02295 bacadf15dc35a8fe2f741b143c780f9b 482 SUPERFAMILY SSF69705 4 126 1.7E-36 T 22-04-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 HRM2_RS02295 bacadf15dc35a8fe2f741b143c780f9b 482 SMART SM00322 304 411 1.0 T 22-04-2016 IPR004087 K Homology domain GO:0003676 HRM2_RS02295 bacadf15dc35a8fe2f741b143c780f9b 482 SMART SM00322 230 303 0.018 T 22-04-2016 IPR004087 K Homology domain GO:0003676 HRM2_RS02295 bacadf15dc35a8fe2f741b143c780f9b 482 SUPERFAMILY SSF47794 351 411 6.59E-10 T 22-04-2016 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 HRM2_RS02295 bacadf15dc35a8fe2f741b143c780f9b 482 SUPERFAMILY SSF54814 200 277 1.7E-29 T 22-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 HRM2_RS02295 bacadf15dc35a8fe2f741b143c780f9b 482 PANTHER PTHR22648:SF0 2 444 8.8E-153 T 22-04-2016 HRM2_RS08935 42b18c047fe87ec0fc6ef873697a2c54 365 SUPERFAMILY SSF56349 84 358 2.94E-61 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HRM2_RS08935 42b18c047fe87ec0fc6ef873697a2c54 365 Gene3D G3DSA:1.10.150.130 89 181 6.8E-10 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal HRM2_RS08935 42b18c047fe87ec0fc6ef873697a2c54 365 Gene3D G3DSA:1.10.443.10 188 361 5.4E-42 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS08935 42b18c047fe87ec0fc6ef873697a2c54 365 PANTHER PTHR30349:SF20 108 365 2.1E-43 T 22-04-2016 HRM2_RS08935 42b18c047fe87ec0fc6ef873697a2c54 365 PANTHER PTHR30349 108 365 2.1E-43 T 22-04-2016 HRM2_RS08935 42b18c047fe87ec0fc6ef873697a2c54 365 Pfam PF00589 Phage integrase family 191 349 1.5E-30 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS08935 42b18c047fe87ec0fc6ef873697a2c54 365 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 87 133 1.4E-5 T 22-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 HRM2_RS13650 c06c1e5bb63d8342f88c849b49a73448 296 TIGRFAM TIGR00761 argB: acetylglutamate kinase 23 266 3.0E-75 T 22-04-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HRM2_RS13650 c06c1e5bb63d8342f88c849b49a73448 296 Hamap MF_00082_B Acetylglutamate kinase [argB]. 20 291 35.736 T 22-04-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HRM2_RS13650 c06c1e5bb63d8342f88c849b49a73448 296 Gene3D G3DSA:3.40.1160.10 21 289 5.7E-103 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HRM2_RS13650 c06c1e5bb63d8342f88c849b49a73448 296 Pfam PF00696 Amino acid kinase family 22 268 5.2E-46 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HRM2_RS13650 c06c1e5bb63d8342f88c849b49a73448 296 PIRSF PIRSF000728 7 290 1.9E-107 T 22-04-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HRM2_RS13650 c06c1e5bb63d8342f88c849b49a73448 296 PANTHER PTHR23342 2 289 2.2E-112 T 22-04-2016 HRM2_RS13650 c06c1e5bb63d8342f88c849b49a73448 296 Hamap MF_00082_A Acetylglutamate kinase [argB]. 23 276 29.806 T 22-04-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HRM2_RS13650 c06c1e5bb63d8342f88c849b49a73448 296 PRINTS PR00474 Glutamate 5-kinase family signature 191 218 5.0E-10 T 22-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 HRM2_RS13650 c06c1e5bb63d8342f88c849b49a73448 296 PRINTS PR00474 Glutamate 5-kinase family signature 53 67 5.0E-10 T 22-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 HRM2_RS13650 c06c1e5bb63d8342f88c849b49a73448 296 PRINTS PR00474 Glutamate 5-kinase family signature 241 261 5.0E-10 T 22-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 HRM2_RS13650 c06c1e5bb63d8342f88c849b49a73448 296 SUPERFAMILY SSF53633 3 289 1.31E-92 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HRM2_RS00880 3f45c173aaaad60161de42daf078448f 283 Gene3D G3DSA:3.50.30.10 159 270 3.9E-33 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS00880 3f45c173aaaad60161de42daf078448f 283 Pfam PF00391 PEP-utilising enzyme, mobile domain 178 251 2.6E-21 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS00880 3f45c173aaaad60161de42daf078448f 283 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 210 221 - T 22-04-2016 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 HRM2_RS00880 3f45c173aaaad60161de42daf078448f 283 PANTHER PTHR22931 95 266 1.8E-38 T 22-04-2016 HRM2_RS00880 3f45c173aaaad60161de42daf078448f 283 SUPERFAMILY SSF47831 60 169 7.19E-27 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 HRM2_RS00880 3f45c173aaaad60161de42daf078448f 283 PANTHER PTHR22931:SF28 95 266 1.8E-38 T 22-04-2016 HRM2_RS00880 3f45c173aaaad60161de42daf078448f 283 Gene3D G3DSA:1.10.274.10 57 158 1.3E-28 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 HRM2_RS00880 3f45c173aaaad60161de42daf078448f 283 Pfam PF05524 PEP-utilising enzyme, N-terminal 31 152 3.4E-23 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 HRM2_RS00880 3f45c173aaaad60161de42daf078448f 283 SUPERFAMILY SSF52009 151 269 1.83E-28 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS13760 71ec9779db2ed95c1b04d889a450159f 388 Pfam PF01837 Homocysteine biosynthesis enzyme, sulfur-incorporation 22 379 1.6E-147 T 22-04-2016 IPR002708 Homocysteine biosynthesis enzyme, sulfur-incorporation HRM2_RS13760 71ec9779db2ed95c1b04d889a450159f 388 ProDom PD011569 METAL-BINDING IRON IRON-SULFUR 4FE-4S FERREDOXIN OXIDOREDUCTASE DOMAIN ELECTRON METHANOGENESIS A 24 300 3.0E-112 T 22-04-2016 IPR002708 Homocysteine biosynthesis enzyme, sulfur-incorporation HRM2_RS15005 e0a451f6f47e0ff4499807ce101a3407 807 SUPERFAMILY SSF54211 612 788 9.48E-56 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS15005 e0a451f6f47e0ff4499807ce101a3407 807 SMART SM00464 25 219 7.2E-55 T 22-04-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 HRM2_RS15005 e0a451f6f47e0ff4499807ce101a3407 807 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 587 788 2.8E-87 T 22-04-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 HRM2_RS15005 e0a451f6f47e0ff4499807ce101a3407 807 Hamap MF_01973 Lon protease [lon]. 26 789 67.307 T 22-04-2016 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 HRM2_RS15005 e0a451f6f47e0ff4499807ce101a3407 807 SUPERFAMILY SSF88697 25 217 2.06E-40 T 22-04-2016 IPR015947 PUA-like domain HRM2_RS15005 e0a451f6f47e0ff4499807ce101a3407 807 PANTHER PTHR10046 1 794 0.0 T 22-04-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 HRM2_RS15005 e0a451f6f47e0ff4499807ce101a3407 807 PIRSF PIRSF001174 13 792 0.0 T 22-04-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 HRM2_RS15005 e0a451f6f47e0ff4499807ce101a3407 807 Gene3D G3DSA:3.40.50.300 329 516 3.5E-35 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS15005 e0a451f6f47e0ff4499807ce101a3407 807 SMART SM00382 365 510 1.1E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS15005 e0a451f6f47e0ff4499807ce101a3407 807 SUPERFAMILY SSF52540 326 598 5.01E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS15005 e0a451f6f47e0ff4499807ce101a3407 807 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 25 218 2.6E-37 T 22-04-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 HRM2_RS15005 e0a451f6f47e0ff4499807ce101a3407 807 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 690 709 5.1E-53 T 22-04-2016 HRM2_RS15005 e0a451f6f47e0ff4499807ce101a3407 807 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 720 739 5.1E-53 T 22-04-2016 HRM2_RS15005 e0a451f6f47e0ff4499807ce101a3407 807 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 743 761 5.1E-53 T 22-04-2016 HRM2_RS15005 e0a451f6f47e0ff4499807ce101a3407 807 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 612 628 5.1E-53 T 22-04-2016 HRM2_RS15005 e0a451f6f47e0ff4499807ce101a3407 807 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 373 392 5.1E-53 T 22-04-2016 HRM2_RS15005 e0a451f6f47e0ff4499807ce101a3407 807 Gene3D G3DSA:3.30.230.10 607 789 2.6E-72 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HRM2_RS15005 e0a451f6f47e0ff4499807ce101a3407 807 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 693 701 - T 22-04-2016 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 HRM2_RS15005 e0a451f6f47e0ff4499807ce101a3407 807 TIGRFAM TIGR00763 lon: endopeptidase La 27 788 8.7E-288 T 22-04-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 HRM2_RS15005 e0a451f6f47e0ff4499807ce101a3407 807 PANTHER PTHR10046:SF24 1 794 0.0 T 22-04-2016 HRM2_RS15005 e0a451f6f47e0ff4499807ce101a3407 807 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 369 506 9.5E-23 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HRM2_RS15005 e0a451f6f47e0ff4499807ce101a3407 807 Gene3D G3DSA:1.10.8.60 517 601 2.4E-28 T 22-04-2016 HRM2_RS03825 e9caec18164d716577954b08f401dc39 359 Gene3D G3DSA:3.50.50.60 3 57 2.4E-10 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS03825 e9caec18164d716577954b08f401dc39 359 Pfam PF13450 NAD(P)-binding Rossmann-like domain 10 76 8.4E-17 T 22-04-2016 HRM2_RS03825 e9caec18164d716577954b08f401dc39 359 PANTHER PTHR10742 4 356 1.8E-42 T 22-04-2016 HRM2_RS03825 e9caec18164d716577954b08f401dc39 359 Gene3D G3DSA:3.90.660.10 131 302 3.5E-31 T 22-04-2016 HRM2_RS03825 e9caec18164d716577954b08f401dc39 359 SUPERFAMILY SSF51905 315 356 6.48E-41 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS03825 e9caec18164d716577954b08f401dc39 359 SUPERFAMILY SSF51905 1 221 6.48E-41 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS03825 e9caec18164d716577954b08f401dc39 359 SUPERFAMILY SSF54373 202 301 9.16E-19 T 22-04-2016 HRM2_RS03825 e9caec18164d716577954b08f401dc39 359 Pfam PF01593 Flavin containing amine oxidoreductase 111 356 1.4E-27 T 22-04-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 HRM2_RS20595 4d4dfe4379d9b2e0253fae28ca3199fa 289 SUPERFAMILY SSF53807 17 286 9.42E-67 T 22-04-2016 HRM2_RS20595 4d4dfe4379d9b2e0253fae28ca3199fa 289 Gene3D G3DSA:3.40.50.1980 156 287 7.6E-33 T 22-04-2016 HRM2_RS20595 4d4dfe4379d9b2e0253fae28ca3199fa 289 PANTHER PTHR30535 19 289 6.6E-66 T 22-04-2016 HRM2_RS20595 4d4dfe4379d9b2e0253fae28ca3199fa 289 Gene3D G3DSA:3.40.50.1980 34 154 2.2E-31 T 22-04-2016 HRM2_RS20595 4d4dfe4379d9b2e0253fae28ca3199fa 289 Pfam PF01497 Periplasmic binding protein 38 264 2.6E-35 T 22-04-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 HRM2_RS09465 0429e602c858f2e7727f3ab0855f64db 96 Gene3D G3DSA:3.30.1340.10 7 92 2.6E-22 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like HRM2_RS09465 0429e602c858f2e7727f3ab0855f64db 96 Pfam PF00381 PTS HPr component phosphorylation site 8 86 8.4E-20 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like HRM2_RS09465 0429e602c858f2e7727f3ab0855f64db 96 PANTHER PTHR33705:SF2 6 94 1.5E-19 T 22-04-2016 HRM2_RS09465 0429e602c858f2e7727f3ab0855f64db 96 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 7 86 2.0E-20 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like HRM2_RS09465 0429e602c858f2e7727f3ab0855f64db 96 PRINTS PR00107 Phosphocarrier protein signature 58 75 2.5E-8 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like HRM2_RS09465 0429e602c858f2e7727f3ab0855f64db 96 PRINTS PR00107 Phosphocarrier protein signature 43 58 2.5E-8 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like HRM2_RS09465 0429e602c858f2e7727f3ab0855f64db 96 PRINTS PR00107 Phosphocarrier protein signature 18 34 2.5E-8 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like HRM2_RS09465 0429e602c858f2e7727f3ab0855f64db 96 SUPERFAMILY SSF55594 8 92 3.27E-19 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like HRM2_RS09465 0429e602c858f2e7727f3ab0855f64db 96 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 18 25 - T 22-04-2016 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site HRM2_RS09465 0429e602c858f2e7727f3ab0855f64db 96 PANTHER PTHR33705 6 94 1.5E-19 T 22-04-2016 HRM2_RS15835 850b230ae2dee8c2da47353d238cf04f 322 Pfam PF03116 NQR2, RnfD, RnfE family 9 315 4.5E-86 T 22-04-2016 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 HRM2_RS15835 850b230ae2dee8c2da47353d238cf04f 322 PANTHER PTHR30578:SF0 4 322 4.5E-63 T 22-04-2016 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 HRM2_RS15835 850b230ae2dee8c2da47353d238cf04f 322 TIGRFAM TIGR01946 rnfD: electron transport complex, RnfABCDGE type, D subunit 12 316 2.3E-69 T 22-04-2016 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 HRM2_RS15835 850b230ae2dee8c2da47353d238cf04f 322 PANTHER PTHR30578 4 322 4.5E-63 T 22-04-2016 HRM2_RS15030 a0fbd56915621a5607eeb3466a899e14 471 Gene3D G3DSA:3.30.420.10 2 189 6.3E-54 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS15030 a0fbd56915621a5607eeb3466a899e14 471 Pfam PF00929 Exonuclease 6 184 2.1E-13 T 22-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III HRM2_RS15030 a0fbd56915621a5607eeb3466a899e14 471 PANTHER PTHR11046:SF2 3 197 5.4E-44 T 22-04-2016 IPR023607 Exodeoxyribonuclease I GO:0004529 HRM2_RS15030 a0fbd56915621a5607eeb3466a899e14 471 SUPERFAMILY SSF53098 1 416 3.08E-63 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS15030 a0fbd56915621a5607eeb3466a899e14 471 SMART SM00479 3 194 7.4E-5 T 22-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III HRM2_RS15030 a0fbd56915621a5607eeb3466a899e14 471 Pfam PF08411 Exonuclease C-terminal 308 468 4.3E-8 T 22-04-2016 IPR013620 Exonuclease C-terminal GO:0006281|GO:0008852 HRM2_RS15030 a0fbd56915621a5607eeb3466a899e14 471 PANTHER PTHR11046 3 197 5.4E-44 T 22-04-2016 HRM2_RS22515 071bc833209b75e2c9fc7da13b4b38b2 270 Pfam PF01261 Xylose isomerase-like TIM barrel 33 210 8.3E-11 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain HRM2_RS22515 071bc833209b75e2c9fc7da13b4b38b2 270 SUPERFAMILY SSF51658 20 261 2.76E-26 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain HRM2_RS22515 071bc833209b75e2c9fc7da13b4b38b2 270 Gene3D G3DSA:3.20.20.150 33 264 2.4E-14 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain HRM2_RS20875 0b6b7cf975cb18c2126c7994fa8052c5 481 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 267 456 8.8E-37 T 22-04-2016 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 UniPathway: UPA00148 HRM2_RS20875 0b6b7cf975cb18c2126c7994fa8052c5 481 SUPERFAMILY SSF52540 10 203 1.88E-40 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20875 0b6b7cf975cb18c2126c7994fa8052c5 481 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 8 460 38.451 T 22-04-2016 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 HRM2_RS20875 0b6b7cf975cb18c2126c7994fa8052c5 481 Gene3D G3DSA:3.40.50.300 9 199 2.5E-27 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20875 0b6b7cf975cb18c2126c7994fa8052c5 481 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 11 184 1.9E-19 T 22-04-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain HRM2_RS20875 0b6b7cf975cb18c2126c7994fa8052c5 481 SUPERFAMILY SSF52317 264 470 1.52E-34 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS20875 0b6b7cf975cb18c2126c7994fa8052c5 481 PANTHER PTHR21343 3 242 4.3E-138 T 22-04-2016 HRM2_RS20875 0b6b7cf975cb18c2126c7994fa8052c5 481 PANTHER PTHR21343 270 478 4.3E-138 T 22-04-2016 HRM2_RS20875 0b6b7cf975cb18c2126c7994fa8052c5 481 Gene3D G3DSA:3.40.50.880 265 473 1.8E-27 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS20875 0b6b7cf975cb18c2126c7994fa8052c5 481 PANTHER PTHR21343:SF6 3 242 4.3E-138 T 22-04-2016 HRM2_RS20875 0b6b7cf975cb18c2126c7994fa8052c5 481 PANTHER PTHR21343:SF6 270 478 4.3E-138 T 22-04-2016 HRM2_RS20875 0b6b7cf975cb18c2126c7994fa8052c5 481 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 11 470 2.3E-123 T 22-04-2016 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 HRM2_RS18780 febce93cc4c3dcab2c121504b4e3c4c5 169 Gene3D G3DSA:1.10.10.10 5 141 3.6E-28 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS18780 febce93cc4c3dcab2c121504b4e3c4c5 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 5.0E-11 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS18780 febce93cc4c3dcab2c121504b4e3c4c5 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 5.0E-11 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS18780 febce93cc4c3dcab2c121504b4e3c4c5 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 5.0E-11 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS18780 febce93cc4c3dcab2c121504b4e3c4c5 169 PANTHER PTHR33164 9 153 1.1E-22 T 22-04-2016 HRM2_RS18780 febce93cc4c3dcab2c121504b4e3c4c5 169 Pfam PF01047 MarR family 39 94 2.0E-13 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS18780 febce93cc4c3dcab2c121504b4e3c4c5 169 SMART SM00347 29 131 1.5E-17 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS18780 febce93cc4c3dcab2c121504b4e3c4c5 169 SUPERFAMILY SSF46785 10 145 3.31E-26 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS01825 2505b6428f0219086c5070a97a99cad6 73 PANTHER PTHR37469:SF2 1 42 4.8E-12 T 22-04-2016 HRM2_RS01825 2505b6428f0219086c5070a97a99cad6 73 PANTHER PTHR37469 1 42 4.8E-12 T 22-04-2016 HRM2_RS03520 0101c29803c1cb802557e5946cf7e4f1 134 Pfam PF03061 Thioesterase superfamily 48 123 2.2E-5 T 22-04-2016 IPR006683 Thioesterase domain HRM2_RS03520 0101c29803c1cb802557e5946cf7e4f1 134 SUPERFAMILY SSF54637 20 133 4.23E-17 T 22-04-2016 IPR029069 HotDog domain HRM2_RS03520 0101c29803c1cb802557e5946cf7e4f1 134 Gene3D G3DSA:3.10.129.10 19 133 3.9E-17 T 22-04-2016 IPR029069 HotDog domain HRM2_RS20640 f4a03116373bba1375ca2073cefbbfdf 195 Pfam PF00072 Response regulator receiver domain 8 114 1.3E-23 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS20640 f4a03116373bba1375ca2073cefbbfdf 195 SMART SM00448 6 119 5.5E-29 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS20640 f4a03116373bba1375ca2073cefbbfdf 195 PANTHER PTHR26402 6 128 5.0E-34 T 22-04-2016 HRM2_RS20640 f4a03116373bba1375ca2073cefbbfdf 195 SUPERFAMILY SSF52172 5 139 2.28E-33 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS20640 f4a03116373bba1375ca2073cefbbfdf 195 Gene3D G3DSA:3.40.50.2300 6 136 2.7E-32 T 22-04-2016 HRM2_RS07550 8fbee962a9d0b78345f7def6af315435 270 Pfam PF01209 ubiE/COQ5 methyltransferase family 46 270 5.5E-66 T 22-04-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 HRM2_RS07550 8fbee962a9d0b78345f7def6af315435 270 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 50 270 2.4E-72 T 22-04-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 HRM2_RS07550 8fbee962a9d0b78345f7def6af315435 270 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 61 76 - T 22-04-2016 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 HRM2_RS07550 8fbee962a9d0b78345f7def6af315435 270 SUPERFAMILY SSF53335 43 264 1.1E-39 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS07550 8fbee962a9d0b78345f7def6af315435 270 PANTHER PTHR10108 29 270 1.0E-80 T 22-04-2016 HRM2_RS07550 8fbee962a9d0b78345f7def6af315435 270 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 178 192 - T 22-04-2016 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 HRM2_RS07550 8fbee962a9d0b78345f7def6af315435 270 Gene3D G3DSA:3.40.50.150 49 266 1.1E-46 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS07550 8fbee962a9d0b78345f7def6af315435 270 PANTHER PTHR10108:SF24 29 270 1.0E-80 T 22-04-2016 HRM2_RS07550 8fbee962a9d0b78345f7def6af315435 270 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 41 270 34.525 T 22-04-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 HRM2_RS05135 c3c0ff7dec9ac976ceaa8644b2b0617d 800 PANTHER PTHR34218:SF2 1 800 1.9E-175 T 22-04-2016 HRM2_RS05135 c3c0ff7dec9ac976ceaa8644b2b0617d 800 Pfam PF01804 Penicillin amidase 46 789 1.2E-185 T 22-04-2016 IPR002692 Penicillin/cephalosporin acylase GO:0016787|GO:0017000 HRM2_RS05135 c3c0ff7dec9ac976ceaa8644b2b0617d 800 PIRSF PIRSF001227 3 800 2.3E-161 T 22-04-2016 IPR014395 Penicillin acylase GO:0016811 HRM2_RS05135 c3c0ff7dec9ac976ceaa8644b2b0617d 800 PANTHER PTHR34218 1 800 1.9E-175 T 22-04-2016 HRM2_RS05135 c3c0ff7dec9ac976ceaa8644b2b0617d 800 Gene3D G3DSA:1.10.439.10 34 198 4.9E-43 T 22-04-2016 IPR023343 Penicillin amidase type, domain1 GO:0016811 HRM2_RS05135 c3c0ff7dec9ac976ceaa8644b2b0617d 800 Gene3D G3DSA:3.60.20.10 413 643 1.5E-84 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal HRM2_RS05135 c3c0ff7dec9ac976ceaa8644b2b0617d 800 Gene3D G3DSA:3.60.20.10 252 328 1.5E-84 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal HRM2_RS05135 c3c0ff7dec9ac976ceaa8644b2b0617d 800 SUPERFAMILY SSF56235 41 800 1.75E-181 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal HRM2_RS05135 c3c0ff7dec9ac976ceaa8644b2b0617d 800 Gene3D G3DSA:2.30.120.10 329 396 3.0E-14 T 22-04-2016 HRM2_RS04265 3b78edfef3b00bc51cc370f89f5a8c88 551 SUPERFAMILY SSF55957 436 546 4.58E-20 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS04265 3b78edfef3b00bc51cc370f89f5a8c88 551 TIGRFAM TIGR01132 pgm: phosphoglucomutase, alpha-D-glucose phosphate-specific 1 545 6.7E-271 T 22-04-2016 IPR005852 Phosphoglucomutase, alpha-D-glucose specific GO:0004614|GO:0005975 KEGG: 00010+5.4.2.2|KEGG: 00030+5.4.2.2|KEGG: 00052+5.4.2.2|KEGG: 00230+5.4.2.2|KEGG: 00500+5.4.2.2|KEGG: 00520+5.4.2.2|KEGG: 00521+5.4.2.2|MetaCyc: PWY-2723|MetaCyc: PWY-3801|MetaCyc: PWY-5384|MetaCyc: PWY-5661|MetaCyc: PWY-5940|MetaCyc: PWY-5941|MetaCyc: PWY-622|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|MetaCyc: PWY-7343 HRM2_RS04265 3b78edfef3b00bc51cc370f89f5a8c88 551 SUPERFAMILY SSF53738 210 317 2.47E-9 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS04265 3b78edfef3b00bc51cc370f89f5a8c88 551 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 229 248 7.2E-5 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS04265 3b78edfef3b00bc51cc370f89f5a8c88 551 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 140 154 7.2E-5 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS04265 3b78edfef3b00bc51cc370f89f5a8c88 551 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 298 313 7.2E-5 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS04265 3b78edfef3b00bc51cc370f89f5a8c88 551 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 211 316 5.2E-14 T 22-04-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS04265 3b78edfef3b00bc51cc370f89f5a8c88 551 Gene3D G3DSA:3.40.120.10 226 310 1.6E-41 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS04265 3b78edfef3b00bc51cc370f89f5a8c88 551 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 480 537 3.9E-8 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS04265 3b78edfef3b00bc51cc370f89f5a8c88 551 SUPERFAMILY SSF53738 26 236 1.58E-49 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS04265 3b78edfef3b00bc51cc370f89f5a8c88 551 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 322 440 1.7E-28 T 22-04-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS04265 3b78edfef3b00bc51cc370f89f5a8c88 551 Gene3D G3DSA:3.30.310.50 468 545 4.4E-28 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS04265 3b78edfef3b00bc51cc370f89f5a8c88 551 SUPERFAMILY SSF53738 307 449 1.33E-31 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS04265 3b78edfef3b00bc51cc370f89f5a8c88 551 Gene3D G3DSA:3.40.120.10 311 447 5.0E-34 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS04265 3b78edfef3b00bc51cc370f89f5a8c88 551 Gene3D G3DSA:3.40.120.10 30 225 1.9E-56 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS04265 3b78edfef3b00bc51cc370f89f5a8c88 551 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 141 150 - T 22-04-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS04265 3b78edfef3b00bc51cc370f89f5a8c88 551 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 40 181 7.8E-37 T 22-04-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HRM2_RS04265 3b78edfef3b00bc51cc370f89f5a8c88 551 PANTHER PTHR22573 18 551 1.6E-262 T 22-04-2016 HRM2_RS04265 3b78edfef3b00bc51cc370f89f5a8c88 551 PANTHER PTHR22573:SF52 18 551 1.6E-262 T 22-04-2016 HRM2_RS15170 fb8fce5486dde0cd4d1f2c07dc710fad 476 Gene3D G3DSA:3.30.43.10 8 94 6.5E-29 T 22-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 HRM2_RS15170 fb8fce5486dde0cd4d1f2c07dc710fad 476 Pfam PF02913 FAD linked oxidases, C-terminal domain 215 458 5.0E-54 T 22-04-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 HRM2_RS15170 fb8fce5486dde0cd4d1f2c07dc710fad 476 PANTHER PTHR11748 6 464 2.6E-140 T 22-04-2016 HRM2_RS15170 fb8fce5486dde0cd4d1f2c07dc710fad 476 Gene3D G3DSA:3.30.465.10 95 215 1.0E-40 T 22-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 HRM2_RS15170 fb8fce5486dde0cd4d1f2c07dc710fad 476 Gene3D G3DSA:1.10.45.10 420 458 2.2E-12 T 22-04-2016 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 HRM2_RS15170 fb8fce5486dde0cd4d1f2c07dc710fad 476 SUPERFAMILY SSF55103 218 463 1.8E-53 T 22-04-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 HRM2_RS15170 fb8fce5486dde0cd4d1f2c07dc710fad 476 SUPERFAMILY SSF56176 6 215 6.07E-68 T 22-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 HRM2_RS15170 fb8fce5486dde0cd4d1f2c07dc710fad 476 PANTHER PTHR11748:SF35 6 464 2.6E-140 T 22-04-2016 HRM2_RS15170 fb8fce5486dde0cd4d1f2c07dc710fad 476 Pfam PF01565 FAD binding domain 41 178 9.6E-43 T 22-04-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 HRM2_RS01525 f87270b26ac8b16148087b20b69b9c82 217 SUPERFAMILY SSF46785 9 75 2.96E-13 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS01525 f87270b26ac8b16148087b20b69b9c82 217 SUPERFAMILY SSF48008 78 206 1.02E-17 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS01525 f87270b26ac8b16148087b20b69b9c82 217 SMART SM00895 82 201 3.1E-8 T 22-04-2016 IPR011711 GntR, C-terminal HRM2_RS01525 f87270b26ac8b16148087b20b69b9c82 217 SMART SM00345 13 71 7.1E-9 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS01525 f87270b26ac8b16148087b20b69b9c82 217 Pfam PF07729 FCD domain 83 196 3.5E-16 T 22-04-2016 IPR011711 GntR, C-terminal HRM2_RS01525 f87270b26ac8b16148087b20b69b9c82 217 Gene3D G3DSA:1.10.10.10 9 72 8.6E-16 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS01525 f87270b26ac8b16148087b20b69b9c82 217 Gene3D G3DSA:1.20.120.530 76 209 9.6E-21 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS01525 f87270b26ac8b16148087b20b69b9c82 217 PANTHER PTHR11751 9 98 1.1E-15 T 22-04-2016 HRM2_RS01525 f87270b26ac8b16148087b20b69b9c82 217 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 71 1.2E-11 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS24105 1e45e09303503c35f292a10e3167bdfe 237 Pfam PF00005 ABC transporter 20 165 1.7E-29 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS24105 1e45e09303503c35f292a10e3167bdfe 237 PANTHER PTHR24220 6 236 9.2E-90 T 22-04-2016 HRM2_RS24105 1e45e09303503c35f292a10e3167bdfe 237 SUPERFAMILY SSF52540 3 235 1.27E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24105 1e45e09303503c35f292a10e3167bdfe 237 SMART SM00382 29 216 1.4E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS24105 1e45e09303503c35f292a10e3167bdfe 237 Gene3D G3DSA:3.40.50.300 2 232 1.9E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24105 1e45e09303503c35f292a10e3167bdfe 237 PANTHER PTHR24220:SF568 6 236 9.2E-90 T 22-04-2016 HRM2_RS12575 a39ecb6444a20e75f591f50468c885fb 443 Pfam PF01943 Polysaccharide biosynthesis protein 23 297 1.5E-19 T 22-04-2016 IPR002797 Polysaccharide biosynthesis protein GO:0016020 HRM2_RS12575 a39ecb6444a20e75f591f50468c885fb 443 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 354 438 6.4E-7 T 22-04-2016 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain HRM2_RS02165 4195b1c00f845f503e7c49e4e15cd9b6 418 PANTHER PTHR11262 2 417 9.7E-233 T 22-04-2016 HRM2_RS02165 4195b1c00f845f503e7c49e4e15cd9b6 418 PANTHER PTHR11262:SF4 2 417 9.7E-233 T 22-04-2016 HRM2_RS02165 4195b1c00f845f503e7c49e4e15cd9b6 418 SUPERFAMILY SSF52540 60 395 4.73E-74 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02165 4195b1c00f845f503e7c49e4e15cd9b6 418 SUPERFAMILY SSF57716 11 46 2.42E-11 T 22-04-2016 HRM2_RS02165 4195b1c00f845f503e7c49e4e15cd9b6 418 Gene3D G3DSA:3.40.50.300 292 309 5.4E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02165 4195b1c00f845f503e7c49e4e15cd9b6 418 Gene3D G3DSA:3.40.50.300 63 253 5.4E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02165 4195b1c00f845f503e7c49e4e15cd9b6 418 Pfam PF07724 AAA domain (Cdc48 subfamily) 111 308 7.0E-47 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HRM2_RS02165 4195b1c00f845f503e7c49e4e15cd9b6 418 SMART SM01086 315 409 7.1E-30 T 22-04-2016 IPR019489 Clp ATPase, C-terminal HRM2_RS02165 4195b1c00f845f503e7c49e4e15cd9b6 418 SMART SM00382 111 273 2.3E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS02165 4195b1c00f845f503e7c49e4e15cd9b6 418 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 315 393 2.0E-16 T 22-04-2016 IPR019489 Clp ATPase, C-terminal HRM2_RS02165 4195b1c00f845f503e7c49e4e15cd9b6 418 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 4 409 3.0E-196 T 22-04-2016 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 HRM2_RS02165 4195b1c00f845f503e7c49e4e15cd9b6 418 SMART SM00994 10 49 4.3E-20 T 22-04-2016 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 HRM2_RS02165 4195b1c00f845f503e7c49e4e15cd9b6 418 Gene3D G3DSA:1.10.8.60 314 413 2.2E-34 T 22-04-2016 HRM2_RS02165 4195b1c00f845f503e7c49e4e15cd9b6 418 Pfam PF06689 ClpX C4-type zinc finger 13 48 2.1E-18 T 22-04-2016 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 HRM2_RS02165 4195b1c00f845f503e7c49e4e15cd9b6 418 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 413 52.053 T 22-04-2016 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 HRM2_RS00760 e88ef6a24ae085277d8ce1d3f7b29b83 205 PANTHER PTHR11938:SF111 152 176 2.7E-33 T 22-04-2016 HRM2_RS00760 e88ef6a24ae085277d8ce1d3f7b29b83 205 PANTHER PTHR11938:SF111 11 134 2.7E-33 T 22-04-2016 HRM2_RS00760 e88ef6a24ae085277d8ce1d3f7b29b83 205 Pfam PF13247 4Fe-4S dicluster domain 74 123 8.5E-10 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS00760 e88ef6a24ae085277d8ce1d3f7b29b83 205 PANTHER PTHR11938 152 176 2.7E-33 T 22-04-2016 HRM2_RS00760 e88ef6a24ae085277d8ce1d3f7b29b83 205 PANTHER PTHR11938 11 134 2.7E-33 T 22-04-2016 HRM2_RS00760 e88ef6a24ae085277d8ce1d3f7b29b83 205 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 109 120 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS00760 e88ef6a24ae085277d8ce1d3f7b29b83 205 Gene3D G3DSA:3.30.70.20 116 188 1.4E-13 T 22-04-2016 HRM2_RS00760 e88ef6a24ae085277d8ce1d3f7b29b83 205 Gene3D G3DSA:3.30.70.20 23 82 1.5E-10 T 22-04-2016 HRM2_RS00760 e88ef6a24ae085277d8ce1d3f7b29b83 205 SUPERFAMILY SSF54862 19 178 6.28E-37 T 22-04-2016 HRM2_RS00760 e88ef6a24ae085277d8ce1d3f7b29b83 205 Gene3D G3DSA:3.30.70.20 83 115 3.3E-15 T 22-04-2016 HRM2_RS17100 161632c9ff6dd09a16d5cbcca9695de5 255 SUPERFAMILY SSF52540 4 229 3.89E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17100 161632c9ff6dd09a16d5cbcca9695de5 255 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS17100 161632c9ff6dd09a16d5cbcca9695de5 255 Pfam PF00005 ABC transporter 20 176 2.9E-34 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS17100 161632c9ff6dd09a16d5cbcca9695de5 255 SMART SM00382 29 223 3.1E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS17100 161632c9ff6dd09a16d5cbcca9695de5 255 PANTHER PTHR24220 6 243 8.3E-78 T 22-04-2016 HRM2_RS17100 161632c9ff6dd09a16d5cbcca9695de5 255 Gene3D G3DSA:3.40.50.300 2 226 2.8E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17100 161632c9ff6dd09a16d5cbcca9695de5 255 PANTHER PTHR24220:SF308 6 243 8.3E-78 T 22-04-2016 HRM2_RS11670 f2d5815780b8d556d0467120d7d40264 350 PANTHER PTHR34069:SF2 2 350 2.2E-62 T 22-04-2016 HRM2_RS11670 f2d5815780b8d556d0467120d7d40264 350 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 117 195 1.2E-6 T 22-04-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 HRM2_RS11670 f2d5815780b8d556d0467120d7d40264 350 Gene3D G3DSA:3.40.47.10 187 350 6.9E-20 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS11670 f2d5815780b8d556d0467120d7d40264 350 Gene3D G3DSA:3.40.47.10 2 186 2.1E-30 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS11670 f2d5815780b8d556d0467120d7d40264 350 SUPERFAMILY SSF53901 15 350 1.92E-31 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS11670 f2d5815780b8d556d0467120d7d40264 350 PANTHER PTHR34069 2 350 2.2E-62 T 22-04-2016 HRM2_RS11670 f2d5815780b8d556d0467120d7d40264 350 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 265 350 2.0E-9 T 22-04-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 HRM2_RS02455 546123accdedbd5ab928bc7509db08f4 257 SMART SM00345 21 82 3.7E-16 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS02455 546123accdedbd5ab928bc7509db08f4 257 SUPERFAMILY SSF46785 13 86 1.18E-18 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS02455 546123accdedbd5ab928bc7509db08f4 257 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 75 1.1E-17 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS02455 546123accdedbd5ab928bc7509db08f4 257 SUPERFAMILY SSF48008 105 234 4.45E-13 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS02455 546123accdedbd5ab928bc7509db08f4 257 Pfam PF07729 FCD domain 109 233 2.1E-14 T 22-04-2016 IPR011711 GntR, C-terminal HRM2_RS02455 546123accdedbd5ab928bc7509db08f4 257 PANTHER PTHR11751 105 123 7.1E-22 T 22-04-2016 HRM2_RS02455 546123accdedbd5ab928bc7509db08f4 257 PANTHER PTHR11751 19 89 7.1E-22 T 22-04-2016 HRM2_RS02455 546123accdedbd5ab928bc7509db08f4 257 Gene3D G3DSA:1.20.120.530 89 240 1.2E-18 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS02455 546123accdedbd5ab928bc7509db08f4 257 Gene3D G3DSA:1.10.10.10 8 76 2.9E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS02455 546123accdedbd5ab928bc7509db08f4 257 SMART SM00895 107 234 2.8E-13 T 22-04-2016 IPR011711 GntR, C-terminal HRM2_RS02455 546123accdedbd5ab928bc7509db08f4 257 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 4.9E-10 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS02455 546123accdedbd5ab928bc7509db08f4 257 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 4.9E-10 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS01765 4df947e19e40b5a3ff1e51444ad9e666 216 Pfam PF10294 Lysine methyltransferase 50 171 1.1E-9 T 22-04-2016 IPR019410 Lysine methyltransferase HRM2_RS01765 4df947e19e40b5a3ff1e51444ad9e666 216 Gene3D G3DSA:3.40.50.150 43 192 5.8E-28 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS01765 4df947e19e40b5a3ff1e51444ad9e666 216 SUPERFAMILY SSF53335 44 196 4.68E-15 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS01765 4df947e19e40b5a3ff1e51444ad9e666 216 PANTHER PTHR14614 51 189 4.1E-19 T 22-04-2016 HRM2_RS19475 5532d1d323be449a46b419d62b51cd23 322 Pfam PF13817 IS66 C-terminal element 270 307 8.5E-15 T 22-04-2016 HRM2_RS19475 5532d1d323be449a46b419d62b51cd23 322 PANTHER PTHR33678:SF1 11 307 7.4E-68 T 22-04-2016 HRM2_RS19475 5532d1d323be449a46b419d62b51cd23 322 PANTHER PTHR33678 11 307 7.4E-68 T 22-04-2016 HRM2_RS19475 5532d1d323be449a46b419d62b51cd23 322 Pfam PF03050 Transposase IS66 family 10 263 3.1E-80 T 22-04-2016 IPR004291 Transposase, IS66 HRM2_RS08545 3da867c2b7a374e1219315b67f17390b 1001 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 229 1001 173.99 T 22-04-2016 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 HRM2_RS08545 3da867c2b7a374e1219315b67f17390b 1001 SUPERFAMILY SSF82697 77 152 5.23E-5 T 22-04-2016 HRM2_RS08545 3da867c2b7a374e1219315b67f17390b 1001 Gene3D G3DSA:3.30.1280.10 82 152 4.6E-5 T 22-04-2016 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 HRM2_RS08545 3da867c2b7a374e1219315b67f17390b 1001 Gene3D G3DSA:3.30.1330.10 241 255 7.9E-23 T 22-04-2016 IPR016188 PurM-like, N-terminal domain HRM2_RS08545 3da867c2b7a374e1219315b67f17390b 1001 Gene3D G3DSA:3.30.1330.10 287 420 7.9E-23 T 22-04-2016 IPR016188 PurM-like, N-terminal domain HRM2_RS08545 3da867c2b7a374e1219315b67f17390b 1001 SUPERFAMILY SSF56042 827 998 1.5E-31 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain HRM2_RS08545 3da867c2b7a374e1219315b67f17390b 1001 SUPERFAMILY SSF55326 286 421 4.19E-31 T 22-04-2016 HRM2_RS08545 3da867c2b7a374e1219315b67f17390b 1001 SUPERFAMILY SSF55326 224 251 4.19E-31 T 22-04-2016 HRM2_RS08545 3da867c2b7a374e1219315b67f17390b 1001 SUPERFAMILY SSF56042 435 654 4.78E-44 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain HRM2_RS08545 3da867c2b7a374e1219315b67f17390b 1001 Pfam PF02769 AIR synthase related protein, C-terminal domain 435 585 5.4E-22 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain HRM2_RS08545 3da867c2b7a374e1219315b67f17390b 1001 Pfam PF02769 AIR synthase related protein, C-terminal domain 829 970 6.5E-16 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain HRM2_RS08545 3da867c2b7a374e1219315b67f17390b 1001 SUPERFAMILY SSF55326 627 822 2.36E-44 T 22-04-2016 HRM2_RS08545 3da867c2b7a374e1219315b67f17390b 1001 Gene3D G3DSA:3.30.1330.10 642 817 2.1E-33 T 22-04-2016 IPR016188 PurM-like, N-terminal domain HRM2_RS08545 3da867c2b7a374e1219315b67f17390b 1001 PANTHER PTHR10099:SF2 3 1001 4.5E-262 T 22-04-2016 HRM2_RS08545 3da867c2b7a374e1219315b67f17390b 1001 Pfam PF00586 AIR synthase related protein, N-terminal domain 296 419 7.0E-8 T 22-04-2016 IPR016188 PurM-like, N-terminal domain HRM2_RS08545 3da867c2b7a374e1219315b67f17390b 1001 Pfam PF00586 AIR synthase related protein, N-terminal domain 692 812 0.018 T 22-04-2016 IPR016188 PurM-like, N-terminal domain HRM2_RS08545 3da867c2b7a374e1219315b67f17390b 1001 PANTHER PTHR10099 3 1001 4.5E-262 T 22-04-2016 HRM2_RS25400 62d4e11075a3c6d90efe638d733647cd 201 SUPERFAMILY SSF53098 72 198 1.52E-38 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS25400 62d4e11075a3c6d90efe638d733647cd 201 PANTHER PTHR10642 72 199 1.0E-38 T 22-04-2016 HRM2_RS25400 62d4e11075a3c6d90efe638d733647cd 201 Pfam PF00075 RNase H 73 199 6.2E-27 T 22-04-2016 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 HRM2_RS25400 62d4e11075a3c6d90efe638d733647cd 201 Gene3D G3DSA:3.30.420.10 72 199 1.2E-35 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS06070 f51d97efd3188c707327c7b6ac70f5d3 233 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 28 223 2.4E-10 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS06070 f51d97efd3188c707327c7b6ac70f5d3 233 PANTHER PTHR30450 1 231 2.3E-84 T 22-04-2016 HRM2_RS06070 f51d97efd3188c707327c7b6ac70f5d3 233 SUPERFAMILY SSF161098 11 214 1.15E-37 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS06070 f51d97efd3188c707327c7b6ac70f5d3 233 Gene3D G3DSA:1.10.3720.10 10 222 4.1E-40 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS06070 f51d97efd3188c707327c7b6ac70f5d3 233 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 117 1.5E-21 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HRM2_RS06070 f51d97efd3188c707327c7b6ac70f5d3 233 PANTHER PTHR30450:SF4 1 231 2.3E-84 T 22-04-2016 HRM2_RS20040 dc8730b7ad36c8513b26247c3b83ffee 440 Gene3D G3DSA:3.40.50.10180 8 260 2.6E-89 T 22-04-2016 HRM2_RS20040 dc8730b7ad36c8513b26247c3b83ffee 440 SUPERFAMILY SSF82544 4 439 1.96E-139 T 22-04-2016 HRM2_RS20040 dc8730b7ad36c8513b26247c3b83ffee 440 PANTHER PTHR12227 6 439 3.7E-167 T 22-04-2016 HRM2_RS20040 dc8730b7ad36c8513b26247c3b83ffee 440 Gene3D G3DSA:3.40.1480.10 261 439 3.6E-73 T 22-04-2016 IPR007835 MOFRL domain HRM2_RS20040 dc8730b7ad36c8513b26247c3b83ffee 440 Pfam PF05161 MOFRL family 328 433 1.1E-39 T 22-04-2016 IPR007835 MOFRL domain HRM2_RS20040 dc8730b7ad36c8513b26247c3b83ffee 440 Pfam PF13660 Domain of unknown function (DUF4147) 8 245 8.7E-79 T 22-04-2016 IPR025286 MOFRL-associated domain HRM2_RS20040 dc8730b7ad36c8513b26247c3b83ffee 440 PANTHER PTHR12227:SF0 6 439 3.7E-167 T 22-04-2016 HRM2_RS23635 1562e33ba2b94d0be839df34d8e06989 544 Gene3D G3DSA:3.20.20.70 123 529 4.6E-79 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS23635 1562e33ba2b94d0be839df34d8e06989 544 Gene3D G3DSA:3.30.70.20 16 103 3.3E-16 T 22-04-2016 HRM2_RS23635 1562e33ba2b94d0be839df34d8e06989 544 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 83 94 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS23635 1562e33ba2b94d0be839df34d8e06989 544 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 28 39 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS23635 1562e33ba2b94d0be839df34d8e06989 544 SUPERFAMILY SSF54862 19 105 7.53E-16 T 22-04-2016 HRM2_RS23635 1562e33ba2b94d0be839df34d8e06989 544 Pfam PF13484 4Fe-4S double cluster binding domain 27 95 8.7E-11 T 22-04-2016 HRM2_RS23635 1562e33ba2b94d0be839df34d8e06989 544 PIRSF PIRSF006429 7 544 4.8E-108 T 22-04-2016 IPR024188 Glutamate synthase large subunit-like protein HRM2_RS23635 1562e33ba2b94d0be839df34d8e06989 544 SUPERFAMILY SSF51395 150 541 1.65E-67 T 22-04-2016 HRM2_RS23635 1562e33ba2b94d0be839df34d8e06989 544 Pfam PF01645 Conserved region in glutamate synthase 177 514 4.8E-58 T 22-04-2016 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 HRM2_RS23635 1562e33ba2b94d0be839df34d8e06989 544 PANTHER PTHR11938 225 509 4.3E-31 T 22-04-2016 HRM2_RS23635 1562e33ba2b94d0be839df34d8e06989 544 PANTHER PTHR11938:SF65 225 509 4.3E-31 T 22-04-2016 HRM2_RS25450 0d3a96fdf8384c647aad0142930c1ead 49 PANTHER PTHR30437:SF5 1 47 3.6E-23 T 22-04-2016 HRM2_RS25450 0d3a96fdf8384c647aad0142930c1ead 49 PANTHER PTHR30437 1 47 3.6E-23 T 22-04-2016 HRM2_RS25450 0d3a96fdf8384c647aad0142930c1ead 49 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 1 39 3.3E-10 T 22-04-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 HRM2_RS25450 0d3a96fdf8384c647aad0142930c1ead 49 SUPERFAMILY SSF54534 1 40 2.22E-8 T 22-04-2016 HRM2_RS25450 0d3a96fdf8384c647aad0142930c1ead 49 Gene3D G3DSA:3.10.50.30 1 48 4.0E-15 T 22-04-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 HRM2_RS21325 9771eb77059b62e1da1631fcf41b1f24 708 SUPERFAMILY SSF52172 11 145 3.56E-36 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS21325 9771eb77059b62e1da1631fcf41b1f24 708 SUPERFAMILY SSF55073 274 442 2.35E-49 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS21325 9771eb77059b62e1da1631fcf41b1f24 708 Pfam PF00563 EAL domain 458 693 2.1E-72 T 22-04-2016 IPR001633 EAL domain HRM2_RS21325 9771eb77059b62e1da1631fcf41b1f24 708 Gene3D G3DSA:3.40.50.2300 7 137 2.8E-35 T 22-04-2016 HRM2_RS21325 9771eb77059b62e1da1631fcf41b1f24 708 SUPERFAMILY SSF55785 153 261 1.55E-8 T 22-04-2016 IPR000014 PAS domain HRM2_RS21325 9771eb77059b62e1da1631fcf41b1f24 708 SMART SM00052 452 698 4.9E-107 T 22-04-2016 IPR001633 EAL domain HRM2_RS21325 9771eb77059b62e1da1631fcf41b1f24 708 SMART SM00267 258 442 5.9E-67 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS21325 9771eb77059b62e1da1631fcf41b1f24 708 Pfam PF00072 Response regulator receiver domain 14 116 1.8E-25 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS21325 9771eb77059b62e1da1631fcf41b1f24 708 PANTHER PTHR33121 431 703 4.1E-86 T 22-04-2016 HRM2_RS21325 9771eb77059b62e1da1631fcf41b1f24 708 Gene3D G3DSA:3.30.70.270 271 449 1.3E-58 T 22-04-2016 HRM2_RS21325 9771eb77059b62e1da1631fcf41b1f24 708 PANTHER PTHR33121:SF13 431 703 4.1E-86 T 22-04-2016 HRM2_RS21325 9771eb77059b62e1da1631fcf41b1f24 708 Pfam PF00990 Diguanylate cyclase, GGDEF domain 269 438 1.2E-47 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS21325 9771eb77059b62e1da1631fcf41b1f24 708 Gene3D G3DSA:3.20.20.450 456 705 3.0E-93 T 22-04-2016 IPR001633 EAL domain HRM2_RS21325 9771eb77059b62e1da1631fcf41b1f24 708 Gene3D G3DSA:3.30.450.20 138 266 3.0E-10 T 22-04-2016 HRM2_RS21325 9771eb77059b62e1da1631fcf41b1f24 708 Pfam PF08447 PAS fold 166 252 2.6E-6 T 22-04-2016 IPR013655 PAS fold-3 GO:0005515 HRM2_RS21325 9771eb77059b62e1da1631fcf41b1f24 708 SMART SM00448 11 124 3.0E-34 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS21325 9771eb77059b62e1da1631fcf41b1f24 708 SUPERFAMILY SSF141868 457 705 5.23E-86 T 22-04-2016 IPR001633 EAL domain HRM2_RS21325 9771eb77059b62e1da1631fcf41b1f24 708 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 267 440 4.1E-43 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS02435 5bfc13daf71ecc8b6528bfcd9ebd4573 257 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 230 250 4.0E-10 T 22-04-2016 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal HRM2_RS02435 5bfc13daf71ecc8b6528bfcd9ebd4573 257 Gene3D G3DSA:3.40.50.300 3 249 7.3E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02435 5bfc13daf71ecc8b6528bfcd9ebd4573 257 SMART SM00382 28 228 2.0E-5 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS02435 5bfc13daf71ecc8b6528bfcd9ebd4573 257 PANTHER PTHR24220:SF358 5 110 1.6E-111 T 22-04-2016 HRM2_RS02435 5bfc13daf71ecc8b6528bfcd9ebd4573 257 PANTHER PTHR24220:SF358 126 254 1.6E-111 T 22-04-2016 HRM2_RS02435 5bfc13daf71ecc8b6528bfcd9ebd4573 257 Pfam PF00005 ABC transporter 19 179 6.6E-29 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS02435 5bfc13daf71ecc8b6528bfcd9ebd4573 257 SUPERFAMILY SSF52540 3 251 7.94E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02435 5bfc13daf71ecc8b6528bfcd9ebd4573 257 PANTHER PTHR24220 5 110 1.6E-111 T 22-04-2016 HRM2_RS02435 5bfc13daf71ecc8b6528bfcd9ebd4573 257 PANTHER PTHR24220 126 254 1.6E-111 T 22-04-2016 HRM2_RS14340 22db6b08bd0534b4ae595a5281420735 410 PANTHER PTHR22572 5 408 7.3E-153 T 22-04-2016 HRM2_RS14340 22db6b08bd0534b4ae595a5281420735 410 SUPERFAMILY SSF51161 297 407 1.26E-17 T 22-04-2016 IPR011004 Trimeric LpxA-like HRM2_RS14340 22db6b08bd0534b4ae595a5281420735 410 PANTHER PTHR22572:SF10 5 408 7.3E-153 T 22-04-2016 HRM2_RS14340 22db6b08bd0534b4ae595a5281420735 410 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 194 204 - T 22-04-2016 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 HRM2_RS14340 22db6b08bd0534b4ae595a5281420735 410 Gene3D G3DSA:3.90.550.10 7 285 3.0E-72 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS14340 22db6b08bd0534b4ae595a5281420735 410 Gene3D G3DSA:3.90.550.10 328 371 3.0E-72 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS14340 22db6b08bd0534b4ae595a5281420735 410 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 5 381 1.4E-145 T 22-04-2016 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 HRM2_RS14340 22db6b08bd0534b4ae595a5281420735 410 Pfam PF00483 Nucleotidyl transferase 6 274 4.1E-63 T 22-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 HRM2_RS14340 22db6b08bd0534b4ae595a5281420735 410 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 95 103 - T 22-04-2016 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 HRM2_RS14340 22db6b08bd0534b4ae595a5281420735 410 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 1 407 47.606 T 22-04-2016 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 HRM2_RS14340 22db6b08bd0534b4ae595a5281420735 410 SUPERFAMILY SSF53448 5 278 8.68E-72 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS14340 22db6b08bd0534b4ae595a5281420735 410 SUPERFAMILY SSF53448 345 361 8.68E-72 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS20310 1e9d28282069fa3c045e3e001524ab59 528 SUPERFAMILY SSF109604 204 317 1.06E-9 T 22-04-2016 HRM2_RS20310 1e9d28282069fa3c045e3e001524ab59 528 Gene3D G3DSA:1.10.3210.10 215 297 5.3E-7 T 22-04-2016 IPR006674 HD domain HRM2_RS20310 1e9d28282069fa3c045e3e001524ab59 528 Gene3D G3DSA:1.10.3210.10 409 505 3.1E-4 T 22-04-2016 IPR006674 HD domain HRM2_RS20310 1e9d28282069fa3c045e3e001524ab59 528 Pfam PF01966 HD domain 231 317 2.5E-5 T 22-04-2016 IPR006674 HD domain HRM2_RS20310 1e9d28282069fa3c045e3e001524ab59 528 SMART SM00065 34 209 1.7E-20 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS20310 1e9d28282069fa3c045e3e001524ab59 528 Gene3D G3DSA:3.30.450.40 19 212 2.2E-35 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS20310 1e9d28282069fa3c045e3e001524ab59 528 SUPERFAMILY SSF55781 18 211 1.05E-27 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS20310 1e9d28282069fa3c045e3e001524ab59 528 Pfam PF01590 GAF domain 34 199 1.4E-15 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS20310 1e9d28282069fa3c045e3e001524ab59 528 PANTHER PTHR11347:SF82 19 248 5.9E-13 T 22-04-2016 HRM2_RS20310 1e9d28282069fa3c045e3e001524ab59 528 PANTHER PTHR11347 19 248 5.9E-13 T 22-04-2016 HRM2_RS20310 1e9d28282069fa3c045e3e001524ab59 528 SUPERFAMILY SSF109604 404 518 2.92E-13 T 22-04-2016 HRM2_RS20310 1e9d28282069fa3c045e3e001524ab59 528 SMART SM00471 226 489 7.4E-8 T 22-04-2016 IPR003607 HD/PDEase domain HRM2_RS20310 1e9d28282069fa3c045e3e001524ab59 528 Pfam PF13487 HD domain 406 471 9.6E-20 T 22-04-2016 HRM2_RS11905 90197936f0ff4573ac55fa5824b6e6b1 186 Pfam PF01551 Peptidase family M23 52 156 2.1E-10 T 22-04-2016 IPR016047 Peptidase M23 HRM2_RS11905 90197936f0ff4573ac55fa5824b6e6b1 186 SUPERFAMILY SSF51261 30 153 1.62E-8 T 22-04-2016 IPR011055 Duplicated hybrid motif HRM2_RS11905 90197936f0ff4573ac55fa5824b6e6b1 186 Gene3D G3DSA:2.70.70.10 43 164 5.7E-12 T 22-04-2016 HRM2_RS23590 34b4d3fee82ef975ffec3636ddd57712 523 Gene3D G3DSA:3.30.420.40 3 253 3.0E-58 T 22-04-2016 HRM2_RS23590 34b4d3fee82ef975ffec3636ddd57712 523 SUPERFAMILY SSF53067 254 506 2.59E-54 T 22-04-2016 HRM2_RS23590 34b4d3fee82ef975ffec3636ddd57712 523 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 252 2.6E-53 T 22-04-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 HRM2_RS23590 34b4d3fee82ef975ffec3636ddd57712 523 Gene3D G3DSA:3.30.420.40 257 509 6.1E-48 T 22-04-2016 HRM2_RS23590 34b4d3fee82ef975ffec3636ddd57712 523 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 285 462 6.0E-28 T 22-04-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 HRM2_RS23590 34b4d3fee82ef975ffec3636ddd57712 523 PIRSF PIRSF000538 3 516 1.1E-113 T 22-04-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 HRM2_RS23590 34b4d3fee82ef975ffec3636ddd57712 523 PANTHER PTHR10196 1 519 4.7E-110 T 22-04-2016 HRM2_RS23590 34b4d3fee82ef975ffec3636ddd57712 523 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 372 392 - T 22-04-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 HRM2_RS23590 34b4d3fee82ef975ffec3636ddd57712 523 SUPERFAMILY SSF53067 5 254 5.83E-55 T 22-04-2016 HRM2_RS08385 5d0dae266f2ecb99536cdf4a41928a0b 528 Gene3D G3DSA:2.40.40.20 369 526 2.8E-47 T 22-04-2016 HRM2_RS08385 5d0dae266f2ecb99536cdf4a41928a0b 528 Pfam PF01568 Molydopterin dinucleotide binding domain 415 521 2.8E-24 T 22-04-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 HRM2_RS08385 5d0dae266f2ecb99536cdf4a41928a0b 528 Gene3D G3DSA:3.40.228.10 1 202 2.3E-71 T 22-04-2016 HRM2_RS08385 5d0dae266f2ecb99536cdf4a41928a0b 528 PANTHER PTHR11615 1 527 2.1E-128 T 22-04-2016 HRM2_RS08385 5d0dae266f2ecb99536cdf4a41928a0b 528 Gene3D G3DSA:3.40.50.740 222 347 8.2E-50 T 22-04-2016 HRM2_RS08385 5d0dae266f2ecb99536cdf4a41928a0b 528 SUPERFAMILY SSF50692 371 526 1.06E-42 T 22-04-2016 IPR009010 Aspartate decarboxylase-like domain HRM2_RS08385 5d0dae266f2ecb99536cdf4a41928a0b 528 Pfam PF00384 Molybdopterin oxidoreductase 2 332 1.4E-66 T 22-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 HRM2_RS08385 5d0dae266f2ecb99536cdf4a41928a0b 528 SUPERFAMILY SSF53706 1 417 2.22E-136 T 22-04-2016 HRM2_RS08385 5d0dae266f2ecb99536cdf4a41928a0b 528 PANTHER PTHR11615:SF162 1 527 2.1E-128 T 22-04-2016 HRM2_RS03790 73e87479df03ea763e74ba7e7c223f71 429 PIRSF PIRSF000141 7 425 3.8E-87 T 22-04-2016 IPR009158 Glycerol-3-phosphate dehydrogenase, GlpB subunit GO:0004368|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|UniPathway: UPA00618 HRM2_RS03790 73e87479df03ea763e74ba7e7c223f71 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 3.1E-6 T 22-04-2016 HRM2_RS03790 73e87479df03ea763e74ba7e7c223f71 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 372 394 3.1E-6 T 22-04-2016 HRM2_RS03790 73e87479df03ea763e74ba7e7c223f71 429 Pfam PF00890 FAD binding domain 10 405 1.1E-19 T 22-04-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain HRM2_RS03790 73e87479df03ea763e74ba7e7c223f71 429 SUPERFAMILY SSF51905 5 74 4.66E-21 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS03790 73e87479df03ea763e74ba7e7c223f71 429 SUPERFAMILY SSF51905 193 419 4.66E-21 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS03790 73e87479df03ea763e74ba7e7c223f71 429 Gene3D G3DSA:3.50.50.60 6 88 8.0E-18 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS03790 73e87479df03ea763e74ba7e7c223f71 429 Gene3D G3DSA:3.50.50.60 211 402 8.0E-18 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS03790 73e87479df03ea763e74ba7e7c223f71 429 SUPERFAMILY SSF51905 7 159 1.42E-6 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS03790 73e87479df03ea763e74ba7e7c223f71 429 TIGRFAM TIGR03378 glycerol3P_GlpB: glycerol-3-phosphate dehydrogenase, anaerobic, B subunit 10 418 2.9E-60 T 22-04-2016 IPR009158 Glycerol-3-phosphate dehydrogenase, GlpB subunit GO:0004368|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|UniPathway: UPA00618 HRM2_RS24160 bbdbbd8693561db9e0a354c15e726b00 180 SUPERFAMILY SSF103473 1 169 7.46E-14 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS24160 bbdbbd8693561db9e0a354c15e726b00 180 Gene3D G3DSA:1.20.1250.20 1 170 4.9E-12 T 22-04-2016 HRM2_RS05735 2065a849d7b2dc147a59d4fe64eb059e 769 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 10 759 3.8E-240 T 22-04-2016 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 UniPathway: UPA00335 HRM2_RS05735 2065a849d7b2dc147a59d4fe64eb059e 769 SUPERFAMILY SSF55821 177 397 7.32E-46 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain HRM2_RS05735 2065a849d7b2dc147a59d4fe64eb059e 769 PIRSF PIRSF006256 2 768 1.9E-282 T 22-04-2016 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 UniPathway: UPA00335 HRM2_RS05735 2065a849d7b2dc147a59d4fe64eb059e 769 PANTHER PTHR10029:SF4 1 768 0.0 T 22-04-2016 HRM2_RS05735 2065a849d7b2dc147a59d4fe64eb059e 769 Pfam PF07503 HypF finger 110 143 7.8E-17 T 22-04-2016 IPR011125 Zinc finger, HypF-type GO:0008270 UniPathway: UPA00335 HRM2_RS05735 2065a849d7b2dc147a59d4fe64eb059e 769 Pfam PF07503 HypF finger 160 192 9.0E-18 T 22-04-2016 IPR011125 Zinc finger, HypF-type GO:0008270 UniPathway: UPA00335 HRM2_RS05735 2065a849d7b2dc147a59d4fe64eb059e 769 ProSitePatterns PS00150 Acylphosphatase signature 1. 11 21 - T 22-04-2016 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 HRM2_RS05735 2065a849d7b2dc147a59d4fe64eb059e 769 Gene3D G3DSA:3.30.70.100 6 90 5.2E-22 T 22-04-2016 HRM2_RS05735 2065a849d7b2dc147a59d4fe64eb059e 769 PANTHER PTHR10029 1 768 0.0 T 22-04-2016 HRM2_RS05735 2065a849d7b2dc147a59d4fe64eb059e 769 SUPERFAMILY SSF54975 5 91 1.55E-20 T 22-04-2016 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 HRM2_RS05735 2065a849d7b2dc147a59d4fe64eb059e 769 Pfam PF01300 Telomere recombination 212 389 1.2E-48 T 22-04-2016 IPR006070 YrdC-like domain GO:0003725 HRM2_RS05735 2065a849d7b2dc147a59d4fe64eb059e 769 Pfam PF00708 Acylphosphatase 6 90 8.5E-19 T 22-04-2016 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 HRM2_RS05735 2065a849d7b2dc147a59d4fe64eb059e 769 Gene3D G3DSA:3.90.870.10 203 384 3.7E-42 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain HRM2_RS00350 95638359285a3d6b55bdcd244c631f52 188 Gene3D G3DSA:1.20.120.520 5 157 5.6E-19 T 22-04-2016 HRM2_RS00350 95638359285a3d6b55bdcd244c631f52 188 Pfam PF01814 Hemerythrin HHE cation binding domain 4 139 3.1E-14 T 22-04-2016 IPR012312 Haemerythrin-like HRM2_RS00350 95638359285a3d6b55bdcd244c631f52 188 PANTHER PTHR39966 1 187 1.0E-21 T 22-04-2016 HRM2_RS09685 77e32c1269ec3eb3dce1335a320cbc3a 1005 SUPERFAMILY SSF52540 221 492 2.46E-27 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09685 77e32c1269ec3eb3dce1335a320cbc3a 1005 PANTHER PTHR30195:SF15 30 944 5.7E-172 T 22-04-2016 HRM2_RS09685 77e32c1269ec3eb3dce1335a320cbc3a 1005 Pfam PF11867 Domain of unknown function (DUF3387) 730 984 5.5E-13 T 22-04-2016 IPR021810 Protein of unknown function DUF3387 HRM2_RS09685 77e32c1269ec3eb3dce1335a320cbc3a 1005 SMART SM00487 261 472 2.9E-14 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS09685 77e32c1269ec3eb3dce1335a320cbc3a 1005 Gene3D G3DSA:3.40.50.300 515 677 7.8E-5 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09685 77e32c1269ec3eb3dce1335a320cbc3a 1005 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 15 695 1.8E-161 T 22-04-2016 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 HRM2_RS09685 77e32c1269ec3eb3dce1335a320cbc3a 1005 Pfam PF04851 Type III restriction enzyme, res subunit 264 435 1.0E-19 T 22-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HRM2_RS09685 77e32c1269ec3eb3dce1335a320cbc3a 1005 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 11 201 1.1E-34 T 22-04-2016 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 HRM2_RS09685 77e32c1269ec3eb3dce1335a320cbc3a 1005 SUPERFAMILY SSF52540 393 432 6.38E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09685 77e32c1269ec3eb3dce1335a320cbc3a 1005 SUPERFAMILY SSF52540 482 700 6.38E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09685 77e32c1269ec3eb3dce1335a320cbc3a 1005 Gene3D G3DSA:3.40.50.300 259 440 1.6E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09685 77e32c1269ec3eb3dce1335a320cbc3a 1005 PANTHER PTHR30195 30 944 5.7E-172 T 22-04-2016 HRM2_RS25310 08b4d84643e228b19ccc8c995878bed5 209 PANTHER PTHR33693 70 209 7.6E-23 T 22-04-2016 HRM2_RS25310 08b4d84643e228b19ccc8c995878bed5 209 Pfam PF03167 Uracil DNA glycosylase superfamily 70 201 2.2E-16 T 22-04-2016 IPR005122 Uracil-DNA glycosylase-like HRM2_RS25310 08b4d84643e228b19ccc8c995878bed5 209 SUPERFAMILY SSF52141 66 207 4.58E-28 T 22-04-2016 IPR005122 Uracil-DNA glycosylase-like HRM2_RS25310 08b4d84643e228b19ccc8c995878bed5 209 PANTHER PTHR33693:SF1 70 209 7.6E-23 T 22-04-2016 HRM2_RS25310 08b4d84643e228b19ccc8c995878bed5 209 Gene3D G3DSA:3.40.470.10 69 208 2.7E-26 T 22-04-2016 IPR005122 Uracil-DNA glycosylase-like HRM2_RS23060 5e45db77185e8d9dc754bb60d4d83808 364 PRINTS PR00502 NUDIX hydrolase family signature 270 285 1.3E-6 T 22-04-2016 IPR020476 NUDIX hydrolase HRM2_RS23060 5e45db77185e8d9dc754bb60d4d83808 364 PRINTS PR00502 NUDIX hydrolase family signature 256 270 1.3E-6 T 22-04-2016 IPR020476 NUDIX hydrolase HRM2_RS23060 5e45db77185e8d9dc754bb60d4d83808 364 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 32 151 2.7E-19 T 22-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 HRM2_RS23060 5e45db77185e8d9dc754bb60d4d83808 364 SUPERFAMILY SSF55811 217 349 2.3E-35 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HRM2_RS23060 5e45db77185e8d9dc754bb60d4d83808 364 Gene3D G3DSA:1.10.340.30 19 119 5.1E-41 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 HRM2_RS23060 5e45db77185e8d9dc754bb60d4d83808 364 SUPERFAMILY SSF48150 2 218 5.97E-72 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 HRM2_RS23060 5e45db77185e8d9dc754bb60d4d83808 364 PANTHER PTHR10359:SF1 1 311 6.5E-90 T 22-04-2016 HRM2_RS23060 5e45db77185e8d9dc754bb60d4d83808 364 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 4 263 2.5E-96 T 22-04-2016 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 HRM2_RS23060 5e45db77185e8d9dc754bb60d4d83808 364 Pfam PF14815 NUDIX domain 234 346 6.3E-20 T 22-04-2016 IPR029119 MutY, C-terminal HRM2_RS23060 5e45db77185e8d9dc754bb60d4d83808 364 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 189 205 - T 22-04-2016 IPR004035 Endonuclease III, iron-sulphur binding site HRM2_RS23060 5e45db77185e8d9dc754bb60d4d83808 364 SMART SM00478 36 187 3.3E-38 T 22-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 HRM2_RS23060 5e45db77185e8d9dc754bb60d4d83808 364 Gene3D G3DSA:3.90.79.10 228 351 1.3E-32 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HRM2_RS23060 5e45db77185e8d9dc754bb60d4d83808 364 PANTHER PTHR10359 1 311 6.5E-90 T 22-04-2016 HRM2_RS23060 5e45db77185e8d9dc754bb60d4d83808 364 Gene3D G3DSA:1.10.1670.10 120 221 5.8E-37 T 22-04-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal HRM2_RS23060 5e45db77185e8d9dc754bb60d4d83808 364 ProSitePatterns PS00893 Nudix box signature. 261 282 - T 22-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 HRM2_RS23670 86985581d89fe89c606200a51896dfdf 329 SMART SM00937 46 156 3.5E-45 T 22-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 HRM2_RS23670 86985581d89fe89c606200a51896dfdf 329 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 206 222 - T 22-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 HRM2_RS23670 86985581d89fe89c606200a51896dfdf 329 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 3 324 2.7E-145 T 22-04-2016 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 HRM2_RS23670 86985581d89fe89c606200a51896dfdf 329 PANTHER PTHR11075 1 325 2.4E-149 T 22-04-2016 HRM2_RS23670 86985581d89fe89c606200a51896dfdf 329 Pfam PF03462 PCRF domain 2 181 3.8E-52 T 22-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 HRM2_RS23670 86985581d89fe89c606200a51896dfdf 329 PANTHER PTHR11075:SF6 1 325 2.4E-149 T 22-04-2016 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 HRM2_RS23670 86985581d89fe89c606200a51896dfdf 329 SUPERFAMILY SSF75620 2 324 3.79E-125 T 22-04-2016 HRM2_RS23670 86985581d89fe89c606200a51896dfdf 329 Gene3D G3DSA:3.30.160.20 189 268 7.4E-38 T 22-04-2016 IPR014720 Double-stranded RNA-binding domain HRM2_RS23670 86985581d89fe89c606200a51896dfdf 329 Gene3D G3DSA:1.20.58.410 2 74 2.3E-15 T 22-04-2016 HRM2_RS23670 86985581d89fe89c606200a51896dfdf 329 Pfam PF00472 RF-1 domain 190 299 8.4E-41 T 22-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 HRM2_RS00660 108561096d6c46bd0832dddac45083d0 385 Gene3D G3DSA:2.40.37.10 246 362 2.8E-25 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 HRM2_RS00660 108561096d6c46bd0832dddac45083d0 385 SUPERFAMILY SSF50621 222 366 2.93E-31 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 HRM2_RS00660 108561096d6c46bd0832dddac45083d0 385 TIGRFAM TIGR01047 nspC: carboxynorspermidine decarboxylase 15 384 3.8E-147 T 22-04-2016 IPR005730 Carboxynorspermidine decarboxylase KEGG: 00330+4.1.1.96|MetaCyc: PWY-6562 HRM2_RS00660 108561096d6c46bd0832dddac45083d0 385 Gene3D G3DSA:3.20.20.10 37 245 3.7E-18 T 22-04-2016 IPR029066 PLP-binding barrel HRM2_RS00660 108561096d6c46bd0832dddac45083d0 385 PANTHER PTHR11482:SF38 12 385 4.5E-183 T 22-04-2016 HRM2_RS00660 108561096d6c46bd0832dddac45083d0 385 PANTHER PTHR11482 12 385 4.5E-183 T 22-04-2016 HRM2_RS00660 108561096d6c46bd0832dddac45083d0 385 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 245 358 4.0E-10 T 22-04-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 HRM2_RS00660 108561096d6c46bd0832dddac45083d0 385 SUPERFAMILY SSF51419 22 255 5.52E-44 T 22-04-2016 IPR029066 PLP-binding barrel HRM2_RS00660 108561096d6c46bd0832dddac45083d0 385 PIRSF PIRSF038941 4 385 3.4E-173 T 22-04-2016 IPR005730 Carboxynorspermidine decarboxylase KEGG: 00330+4.1.1.96|MetaCyc: PWY-6562 HRM2_RS13140 fe4d19eb3a66d17919b24f8a66ab2b66 844 Pfam PF08482 ATP-dependent helicase C-terminal 694 831 2.9E-48 T 22-04-2016 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal HRM2_RS13140 fe4d19eb3a66d17919b24f8a66ab2b66 844 Gene3D G3DSA:3.40.50.300 212 349 6.4E-17 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13140 fe4d19eb3a66d17919b24f8a66ab2b66 844 Pfam PF00270 DEAD/DEAH box helicase 18 163 8.3E-7 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HRM2_RS13140 fe4d19eb3a66d17919b24f8a66ab2b66 844 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 6 842 1.1E-287 T 22-04-2016 IPR010225 RNA helicase, ATP-dependent DEAH box, HrpB-type HRM2_RS13140 fe4d19eb3a66d17919b24f8a66ab2b66 844 PIRSF PIRSF005496 1 844 2.1E-297 T 22-04-2016 IPR010225 RNA helicase, ATP-dependent DEAH box, HrpB-type HRM2_RS13140 fe4d19eb3a66d17919b24f8a66ab2b66 844 Gene3D G3DSA:3.40.50.300 6 164 4.4E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13140 fe4d19eb3a66d17919b24f8a66ab2b66 844 SUPERFAMILY SSF52540 16 346 2.4E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13140 fe4d19eb3a66d17919b24f8a66ab2b66 844 Pfam PF00271 Helicase conserved C-terminal domain 213 336 8.3E-16 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS13140 fe4d19eb3a66d17919b24f8a66ab2b66 844 SMART SM00487 7 192 2.4E-15 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS13140 fe4d19eb3a66d17919b24f8a66ab2b66 844 SMART SM00847 396 484 5.4E-12 T 22-04-2016 IPR007502 Helicase-associated domain GO:0004386 HRM2_RS13140 fe4d19eb3a66d17919b24f8a66ab2b66 844 PANTHER PTHR18934 6 479 2.8E-147 T 22-04-2016 HRM2_RS13140 fe4d19eb3a66d17919b24f8a66ab2b66 844 Pfam PF04408 Helicase associated domain (HA2) 397 457 1.8E-11 T 22-04-2016 IPR007502 Helicase-associated domain GO:0004386 HRM2_RS13140 fe4d19eb3a66d17919b24f8a66ab2b66 844 SMART SM00490 238 336 4.8E-19 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS02720 3f1257881c553fb5b5c2e144e50b2519 310 TIGRFAM TIGR02590 cas_Csh2: CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI 8 283 9.7E-64 T 22-04-2016 IPR013419 CRISPR-associated protein Csh2 HRM2_RS02720 3f1257881c553fb5b5c2e144e50b2519 310 Pfam PF05107 CRISPR-associated protein Cas7 8 257 8.2E-47 T 22-04-2016 IPR006482 CRISPR-associated protein Cas7, subtype I-B/I-C HRM2_RS02720 3f1257881c553fb5b5c2e144e50b2519 310 TIGRFAM TIGR01595 cas_CT1132: CRISPR-associated protein, CT1132 family 5 268 1.4E-48 T 22-04-2016 IPR006482 CRISPR-associated protein Cas7, subtype I-B/I-C HRM2_RS20925 b603660534836cd4edba0ddcf8e96592 120 SUPERFAMILY SSF53146 1 119 2.09E-31 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS20925 b603660534836cd4edba0ddcf8e96592 120 PANTHER PTHR33937:SF2 1 118 7.3E-28 T 22-04-2016 HRM2_RS20925 b603660534836cd4edba0ddcf8e96592 120 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 103 7.1E-22 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS20925 b603660534836cd4edba0ddcf8e96592 120 Gene3D G3DSA:3.30.420.130 1 114 7.2E-34 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS20925 b603660534836cd4edba0ddcf8e96592 120 PANTHER PTHR33937 1 118 7.3E-28 T 22-04-2016 HRM2_RS10935 abf4e221520ef9e9b54b22478b44ef49 46 Pfam PF02662 Methyl-viologen-reducing hydrogenase, delta subunit 1 36 3.5E-6 T 22-04-2016 IPR003813 Methyl-viologen-reducing hydrogenase, delta subunit GO:0015948|GO:0055114 HRM2_RS12080 1217e0a94592504b30f25621fa364095 723 TIGRFAM TIGR02471 sucr_syn_bact_C: sucrose-phosphate synthase, sucrose phosphatase-like domain 472 706 1.3E-84 T 22-04-2016 IPR012821 Sucrose phosphate synthase, sucrose phosphatase-like domain HRM2_RS12080 1217e0a94592504b30f25621fa364095 723 SUPERFAMILY SSF56784 470 679 5.81E-21 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS12080 1217e0a94592504b30f25621fa364095 723 TIGRFAM TIGR02472 sucr_P_syn_N: sucrose-phosphate synthase, putative, glycosyltransferase domain 8 445 1.5E-199 T 22-04-2016 IPR012822 Sucrose-phosphate synthase, glycosyltransferase domain HRM2_RS12080 1217e0a94592504b30f25621fa364095 723 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 472 666 1.5E-11 T 22-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 HRM2_RS12080 1217e0a94592504b30f25621fa364095 723 PANTHER PTHR12526:SF386 9 488 9.7E-142 T 22-04-2016 HRM2_RS12080 1217e0a94592504b30f25621fa364095 723 Pfam PF05116 Sucrose-6F-phosphate phosphohydrolase 470 706 3.1E-73 T 22-04-2016 IPR006380 Sucrose-phosphatase, N-terminal HRM2_RS12080 1217e0a94592504b30f25621fa364095 723 Gene3D G3DSA:3.40.50.2000 214 425 3.3E-27 T 22-04-2016 HRM2_RS12080 1217e0a94592504b30f25621fa364095 723 Pfam PF00862 Sucrose synthase 10 217 3.2E-15 T 22-04-2016 IPR000368 Sucrose synthase GO:0005985|GO:0016157 HRM2_RS12080 1217e0a94592504b30f25621fa364095 723 Gene3D G3DSA:3.90.1070.10 557 621 2.5E-17 T 22-04-2016 HRM2_RS12080 1217e0a94592504b30f25621fa364095 723 Pfam PF00534 Glycosyl transferases group 1 248 424 3.5E-29 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 HRM2_RS12080 1217e0a94592504b30f25621fa364095 723 PANTHER PTHR12526 9 488 9.7E-142 T 22-04-2016 HRM2_RS12080 1217e0a94592504b30f25621fa364095 723 Gene3D G3DSA:3.40.50.1000 622 704 7.3E-26 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS12080 1217e0a94592504b30f25621fa364095 723 Gene3D G3DSA:3.40.50.1000 470 547 7.3E-26 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS12080 1217e0a94592504b30f25621fa364095 723 SUPERFAMILY SSF53756 25 445 4.32E-72 T 22-04-2016 HRM2_RS25015 5518c9959c8cd452e96f0c5043fa42db 233 Gene3D G3DSA:3.30.70.20 130 180 2.5E-11 T 22-04-2016 HRM2_RS25015 5518c9959c8cd452e96f0c5043fa42db 233 Gene3D G3DSA:3.30.70.20 94 129 9.8E-10 T 22-04-2016 HRM2_RS25015 5518c9959c8cd452e96f0c5043fa42db 233 SUPERFAMILY SSF54862 46 173 5.33E-21 T 22-04-2016 HRM2_RS25015 5518c9959c8cd452e96f0c5043fa42db 233 Pfam PF14697 4Fe-4S dicluster domain 114 169 9.2E-9 T 22-04-2016 HRM2_RS25015 5518c9959c8cd452e96f0c5043fa42db 233 PANTHER PTHR30176:SF3 35 176 1.4E-12 T 22-04-2016 HRM2_RS25015 5518c9959c8cd452e96f0c5043fa42db 233 Gene3D G3DSA:1.10.1060.10 20 57 5.6E-6 T 22-04-2016 HRM2_RS25015 5518c9959c8cd452e96f0c5043fa42db 233 PANTHER PTHR30176 35 176 1.4E-12 T 22-04-2016 HRM2_RS25015 5518c9959c8cd452e96f0c5043fa42db 233 Gene3D G3DSA:3.30.70.20 58 93 3.4E-11 T 22-04-2016 HRM2_RS25015 5518c9959c8cd452e96f0c5043fa42db 233 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 49 60 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS25015 5518c9959c8cd452e96f0c5043fa42db 233 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 157 168 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS25015 5518c9959c8cd452e96f0c5043fa42db 233 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 86 97 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS25015 5518c9959c8cd452e96f0c5043fa42db 233 Pfam PF13187 4Fe-4S dicluster domain 49 101 3.6E-7 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS25015 5518c9959c8cd452e96f0c5043fa42db 233 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 4 32 7.9E-5 T 22-04-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal HRM2_RS17135 a3f0d48157eae19a3bd43b5905fdfb54 228 PANTHER PTHR12725 1 227 1.5E-31 T 22-04-2016 HRM2_RS17135 a3f0d48157eae19a3bd43b5905fdfb54 228 Pfam PF13419 Haloacid dehalogenase-like hydrolase 97 199 2.4E-16 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS17135 a3f0d48157eae19a3bd43b5905fdfb54 228 Gene3D G3DSA:3.40.50.1000 93 226 1.8E-36 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS17135 a3f0d48157eae19a3bd43b5905fdfb54 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 112 125 9.5E-38 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HRM2_RS17135 a3f0d48157eae19a3bd43b5905fdfb54 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 143 159 9.5E-38 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HRM2_RS17135 a3f0d48157eae19a3bd43b5905fdfb54 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 161 181 9.5E-38 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HRM2_RS17135 a3f0d48157eae19a3bd43b5905fdfb54 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 188 201 9.5E-38 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HRM2_RS17135 a3f0d48157eae19a3bd43b5905fdfb54 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 50 63 9.5E-38 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HRM2_RS17135 a3f0d48157eae19a3bd43b5905fdfb54 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 10 21 9.5E-38 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HRM2_RS17135 a3f0d48157eae19a3bd43b5905fdfb54 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 36 49 9.5E-38 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HRM2_RS17135 a3f0d48157eae19a3bd43b5905fdfb54 228 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 10 204 3.6E-68 T 22-04-2016 IPR006328 Haloacid dehalogenase, type II GO:0008152|GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 HRM2_RS17135 a3f0d48157eae19a3bd43b5905fdfb54 228 SUPERFAMILY SSF56784 9 223 1.33E-49 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS17135 a3f0d48157eae19a3bd43b5905fdfb54 228 Gene3D G3DSA:1.10.150.240 24 92 6.1E-28 T 22-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 HRM2_RS17135 a3f0d48157eae19a3bd43b5905fdfb54 228 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 13 192 2.3E-34 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HRM2_RS01035 2bad114b97226667aafb3c6e249dd45f 839 SUPERFAMILY SSF52540 134 426 3.1E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01035 2bad114b97226667aafb3c6e249dd45f 839 SMART SM00341 625 705 5.2E-15 T 22-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 HRM2_RS01035 2bad114b97226667aafb3c6e249dd45f 839 Pfam PF00570 HRDC domain 630 695 2.5E-19 T 22-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 HRM2_RS01035 2bad114b97226667aafb3c6e249dd45f 839 SUPERFAMILY SSF47819 628 706 1.48E-18 T 22-04-2016 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 HRM2_RS01035 2bad114b97226667aafb3c6e249dd45f 839 Pfam PF02689 Helicase 366 412 2.3E-4 T 22-04-2016 IPR003840 DNA helicase GO:0004386|GO:0005524 HRM2_RS01035 2bad114b97226667aafb3c6e249dd45f 839 Pfam PF05970 PIF1-like helicase 19 295 9.3E-30 T 22-04-2016 IPR010285 DNA helicase Pif1-like GO:0000723|GO:0003678|GO:0006281 HRM2_RS01035 2bad114b97226667aafb3c6e249dd45f 839 Gene3D G3DSA:3.40.50.300 144 258 5.3E-28 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01035 2bad114b97226667aafb3c6e249dd45f 839 Gene3D G3DSA:3.40.50.300 355 410 5.3E-28 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01035 2bad114b97226667aafb3c6e249dd45f 839 PANTHER PTHR23274 21 533 1.9E-107 T 22-04-2016 IPR003840 DNA helicase GO:0004386|GO:0005524 HRM2_RS01035 2bad114b97226667aafb3c6e249dd45f 839 Gene3D G3DSA:3.40.50.300 19 143 1.6E-9 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01035 2bad114b97226667aafb3c6e249dd45f 839 SMART SM00382 18 296 5.1E-4 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS01035 2bad114b97226667aafb3c6e249dd45f 839 Gene3D G3DSA:1.10.150.80 629 703 2.4E-15 T 22-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 HRM2_RS01035 2bad114b97226667aafb3c6e249dd45f 839 Pfam PF14493 Helix-turn-helix domain 739 825 1.8E-25 T 22-04-2016 IPR029491 Helicase Helix-turn-helix domain HRM2_RS01035 2bad114b97226667aafb3c6e249dd45f 839 SUPERFAMILY SSF52540 18 213 5.89E-21 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14515 517f3813f489acd2e85b39cd6ee8e789 270 Gene3D G3DSA:3.40.1390.30 4 111 8.7E-40 T 22-04-2016 HRM2_RS14515 517f3813f489acd2e85b39cd6ee8e789 270 PANTHER PTHR13799 5 270 1.0E-74 T 22-04-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 HRM2_RS14515 517f3813f489acd2e85b39cd6ee8e789 270 SUPERFAMILY SSF102705 5 268 1.24E-80 T 22-04-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 HRM2_RS14515 517f3813f489acd2e85b39cd6ee8e789 270 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 6 261 4.4E-60 T 22-04-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 HRM2_RS14515 517f3813f489acd2e85b39cd6ee8e789 270 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 7 249 5.8E-74 T 22-04-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 HRM2_RS14515 517f3813f489acd2e85b39cd6ee8e789 270 Gene3D G3DSA:3.40.1390.30 112 228 5.9E-32 T 22-04-2016 HRM2_RS24430 ac30b1ea9f33b1c7bf32e5b5aa29b33e 786 SMART SM00382 358 503 5.7E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS24430 ac30b1ea9f33b1c7bf32e5b5aa29b33e 786 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 19 211 3.8E-34 T 22-04-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 HRM2_RS24430 ac30b1ea9f33b1c7bf32e5b5aa29b33e 786 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 690 698 - T 22-04-2016 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 HRM2_RS24430 ac30b1ea9f33b1c7bf32e5b5aa29b33e 786 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 584 785 2.0E-87 T 22-04-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 HRM2_RS24430 ac30b1ea9f33b1c7bf32e5b5aa29b33e 786 SUPERFAMILY SSF52540 317 587 3.24E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24430 ac30b1ea9f33b1c7bf32e5b5aa29b33e 786 SMART SM00464 18 212 8.7E-45 T 22-04-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 HRM2_RS24430 ac30b1ea9f33b1c7bf32e5b5aa29b33e 786 SUPERFAMILY SSF54211 609 784 3.11E-55 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS24430 ac30b1ea9f33b1c7bf32e5b5aa29b33e 786 Hamap MF_01973 Lon protease [lon]. 19 786 68.402 T 22-04-2016 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 HRM2_RS24430 ac30b1ea9f33b1c7bf32e5b5aa29b33e 786 Gene3D G3DSA:3.40.50.300 317 510 1.4E-35 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24430 ac30b1ea9f33b1c7bf32e5b5aa29b33e 786 TIGRFAM TIGR00763 lon: endopeptidase La 20 785 3.4E-297 T 22-04-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 HRM2_RS24430 ac30b1ea9f33b1c7bf32e5b5aa29b33e 786 Gene3D G3DSA:1.10.8.60 511 598 3.3E-29 T 22-04-2016 HRM2_RS24430 ac30b1ea9f33b1c7bf32e5b5aa29b33e 786 PANTHER PTHR10046 15 786 0.0 T 22-04-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 HRM2_RS24430 ac30b1ea9f33b1c7bf32e5b5aa29b33e 786 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 366 385 1.8E-53 T 22-04-2016 HRM2_RS24430 ac30b1ea9f33b1c7bf32e5b5aa29b33e 786 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 609 625 1.8E-53 T 22-04-2016 HRM2_RS24430 ac30b1ea9f33b1c7bf32e5b5aa29b33e 786 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 717 736 1.8E-53 T 22-04-2016 HRM2_RS24430 ac30b1ea9f33b1c7bf32e5b5aa29b33e 786 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 740 758 1.8E-53 T 22-04-2016 HRM2_RS24430 ac30b1ea9f33b1c7bf32e5b5aa29b33e 786 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 687 706 1.8E-53 T 22-04-2016 HRM2_RS24430 ac30b1ea9f33b1c7bf32e5b5aa29b33e 786 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 362 498 6.4E-20 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HRM2_RS24430 ac30b1ea9f33b1c7bf32e5b5aa29b33e 786 SUPERFAMILY SSF88697 19 211 5.72E-37 T 22-04-2016 IPR015947 PUA-like domain HRM2_RS24430 ac30b1ea9f33b1c7bf32e5b5aa29b33e 786 PANTHER PTHR10046:SF24 15 786 0.0 T 22-04-2016 HRM2_RS24430 ac30b1ea9f33b1c7bf32e5b5aa29b33e 786 Gene3D G3DSA:3.30.230.10 607 784 7.1E-73 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HRM2_RS24430 ac30b1ea9f33b1c7bf32e5b5aa29b33e 786 PIRSF PIRSF001174 7 786 0.0 T 22-04-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 HRM2_RS11915 2a79037bb213430432090293ff1abd4d 214 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 187 1.2E-15 T 22-04-2016 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type HRM2_RS11915 2a79037bb213430432090293ff1abd4d 214 Gene3D G3DSA:3.60.21.10 1 202 1.0E-29 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS11915 2a79037bb213430432090293ff1abd4d 214 PANTHER PTHR12905 1 189 1.6E-16 T 22-04-2016 HRM2_RS11915 2a79037bb213430432090293ff1abd4d 214 SUPERFAMILY SSF56300 1 205 1.74E-49 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS11915 2a79037bb213430432090293ff1abd4d 214 PANTHER PTHR12905:SF0 1 189 1.6E-16 T 22-04-2016 HRM2_RS20300 edf3cec649f7e37cfe06644a10855be3 383 Gene3D G3DSA:3.40.640.10 14 244 5.2E-87 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS20300 edf3cec649f7e37cfe06644a10855be3 383 SUPERFAMILY SSF53383 1 373 1.29E-106 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS20300 edf3cec649f7e37cfe06644a10855be3 383 PANTHER PTHR11601 2 383 1.5E-177 T 22-04-2016 HRM2_RS20300 edf3cec649f7e37cfe06644a10855be3 383 PIRSF PIRSF005572 1 378 1.5E-132 T 22-04-2016 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 HRM2_RS20300 edf3cec649f7e37cfe06644a10855be3 383 PANTHER PTHR11601:SF20 2 383 1.5E-177 T 22-04-2016 HRM2_RS20300 edf3cec649f7e37cfe06644a10855be3 383 Gene3D G3DSA:3.90.1150.10 245 368 9.5E-46 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS20300 edf3cec649f7e37cfe06644a10855be3 383 TIGRFAM TIGR03402 FeS_nifS: cysteine desulfurase NifS 2 380 5.8E-187 T 22-04-2016 IPR017772 Cysteine desulfurase NifS, bacterial/archaeal GO:0006520|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 HRM2_RS20300 edf3cec649f7e37cfe06644a10855be3 383 Pfam PF00266 Aminotransferase class-V 2 361 5.2E-93 T 22-04-2016 IPR000192 Aminotransferase class V domain HRM2_RS20300 edf3cec649f7e37cfe06644a10855be3 383 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 190 209 - T 22-04-2016 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site HRM2_RS20020 dcbb321087da41ae924a22f9dd3b9231 547 Gene3D G3DSA:3.40.50.2030 223 374 1.7E-66 T 22-04-2016 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS20020 dcbb321087da41ae924a22f9dd3b9231 547 Gene3D G3DSA:1.20.1270.20 148 220 2.1E-26 T 22-04-2016 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS20020 dcbb321087da41ae924a22f9dd3b9231 547 Gene3D G3DSA:1.20.1270.20 1 147 3.5E-43 T 22-04-2016 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS20020 dcbb321087da41ae924a22f9dd3b9231 547 Gene3D G3DSA:3.40.50.2030 375 543 4.5E-72 T 22-04-2016 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS20020 dcbb321087da41ae924a22f9dd3b9231 547 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 1 543 2.1E-223 T 22-04-2016 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS20020 dcbb321087da41ae924a22f9dd3b9231 547 SUPERFAMILY SSF56821 1 544 8.77E-203 T 22-04-2016 IPR011254 Prismane-like GO:0003824|GO:0016491|GO:0055114 HRM2_RS20020 dcbb321087da41ae924a22f9dd3b9231 547 Pfam PF03063 Prismane/CO dehydrogenase family 1 540 1.2E-171 T 22-04-2016 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS20020 dcbb321087da41ae924a22f9dd3b9231 547 PANTHER PTHR30109:SF0 1 545 2.1E-273 T 22-04-2016 HRM2_RS20020 dcbb321087da41ae924a22f9dd3b9231 547 Hamap MF_00069 Hydroxylamine reductase [hcp]. 1 545 23.042 T 22-04-2016 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS20020 dcbb321087da41ae924a22f9dd3b9231 547 PIRSF PIRSF000076 1 546 2.1E-252 T 22-04-2016 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS20020 dcbb321087da41ae924a22f9dd3b9231 547 PANTHER PTHR30109 1 545 2.1E-273 T 22-04-2016 HRM2_RS06585 3b7f2f2d14014808a639e921e027763f 475 Gene3D G3DSA:1.10.8.60 319 391 7.5E-21 T 22-04-2016 HRM2_RS06585 3b7f2f2d14014808a639e921e027763f 475 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 359 368 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS06585 3b7f2f2d14014808a639e921e027763f 475 Gene3D G3DSA:3.40.50.2300 1 120 6.3E-9 T 22-04-2016 HRM2_RS06585 3b7f2f2d14014808a639e921e027763f 475 SUPERFAMILY SSF52172 2 191 4.69E-12 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS06585 3b7f2f2d14014808a639e921e027763f 475 SUPERFAMILY SSF52540 149 388 3.62E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06585 3b7f2f2d14014808a639e921e027763f 475 Pfam PF02954 Bacterial regulatory protein, Fis family 420 458 1.8E-5 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS06585 3b7f2f2d14014808a639e921e027763f 475 SMART SM00382 166 310 2.1E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS06585 3b7f2f2d14014808a639e921e027763f 475 Pfam PF00158 Sigma-54 interaction domain 148 312 3.4E-64 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS06585 3b7f2f2d14014808a639e921e027763f 475 Gene3D G3DSA:1.10.10.60 414 461 7.8E-8 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS06585 3b7f2f2d14014808a639e921e027763f 475 SUPERFAMILY SSF46689 359 461 8.06E-8 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS06585 3b7f2f2d14014808a639e921e027763f 475 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 232 247 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS06585 3b7f2f2d14014808a639e921e027763f 475 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 170 183 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS06585 3b7f2f2d14014808a639e921e027763f 475 Gene3D G3DSA:3.40.50.300 149 318 7.7E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06585 3b7f2f2d14014808a639e921e027763f 475 PANTHER PTHR32071 1 471 5.4E-149 T 22-04-2016 HRM2_RS07730 a1ffac99d1b2282bb1cc38a33d2a2b7e 766 PANTHER PTHR12145:SF11 63 757 1.1E-283 T 22-04-2016 HRM2_RS07730 a1ffac99d1b2282bb1cc38a33d2a2b7e 766 Gene3D G3DSA:1.50.10.10 432 605 3.0E-20 T 22-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 HRM2_RS07730 a1ffac99d1b2282bb1cc38a33d2a2b7e 766 Gene3D G3DSA:1.50.10.10 287 391 3.0E-20 T 22-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 HRM2_RS07730 a1ffac99d1b2282bb1cc38a33d2a2b7e 766 PANTHER PTHR12145 63 757 1.1E-283 T 22-04-2016 HRM2_RS07730 a1ffac99d1b2282bb1cc38a33d2a2b7e 766 SUPERFAMILY SSF48208 242 611 3.32E-65 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 HRM2_RS07730 a1ffac99d1b2282bb1cc38a33d2a2b7e 766 PIRSF PIRSF006402 45 758 5.8E-242 T 22-04-2016 IPR024705 Spermatogenesis-associated protein 20 HRM2_RS07730 a1ffac99d1b2282bb1cc38a33d2a2b7e 766 Gene3D G3DSA:3.40.30.10 81 208 1.4E-33 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS07730 a1ffac99d1b2282bb1cc38a33d2a2b7e 766 Pfam PF03190 Protein of unknown function, DUF255 63 226 3.5E-70 T 22-04-2016 IPR004879 Domain of unknown function DUF255 HRM2_RS07730 a1ffac99d1b2282bb1cc38a33d2a2b7e 766 SUPERFAMILY SSF52833 62 188 2.6E-31 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS19895 84c9753597e567cfb03fd2d13a4bc515 404 PANTHER PTHR26402:SF471 281 398 3.6E-37 T 22-04-2016 HRM2_RS19895 84c9753597e567cfb03fd2d13a4bc515 404 Gene3D G3DSA:3.40.50.300 1 183 4.8E-23 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19895 84c9753597e567cfb03fd2d13a4bc515 404 SMART SM00448 281 392 2.0E-31 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS19895 84c9753597e567cfb03fd2d13a4bc515 404 Pfam PF13189 Cytidylate kinase-like family 5 167 7.1E-13 T 22-04-2016 IPR026865 Cytidylate kinase-like family MetaCyc: PWY-7205 HRM2_RS19895 84c9753597e567cfb03fd2d13a4bc515 404 Pfam PF00072 Response regulator receiver domain 283 392 6.5E-27 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS19895 84c9753597e567cfb03fd2d13a4bc515 404 PANTHER PTHR26402 281 398 3.6E-37 T 22-04-2016 HRM2_RS19895 84c9753597e567cfb03fd2d13a4bc515 404 Gene3D G3DSA:3.40.50.2300 282 397 3.8E-33 T 22-04-2016 HRM2_RS19895 84c9753597e567cfb03fd2d13a4bc515 404 SUPERFAMILY SSF52172 280 398 3.27E-33 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS03765 a2bf08646a5eae0ce5be9d0cde1c9598 234 SUPERFAMILY SSF53681 118 229 2.45E-32 T 22-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS03765 a2bf08646a5eae0ce5be9d0cde1c9598 234 PANTHER PTHR21198:SF7 1 228 1.2E-82 T 22-04-2016 HRM2_RS03765 a2bf08646a5eae0ce5be9d0cde1c9598 234 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 224 1.5E-59 T 22-04-2016 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS03765 a2bf08646a5eae0ce5be9d0cde1c9598 234 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 230 6.5E-70 T 22-04-2016 IPR004380 Aspartate racemase GO:0006520|GO:0016855 HRM2_RS03765 a2bf08646a5eae0ce5be9d0cde1c9598 234 SUPERFAMILY SSF53681 1 112 4.14E-36 T 22-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS03765 a2bf08646a5eae0ce5be9d0cde1c9598 234 PANTHER PTHR21198 1 228 1.2E-82 T 22-04-2016 HRM2_RS03765 a2bf08646a5eae0ce5be9d0cde1c9598 234 Gene3D G3DSA:3.40.50.1860 113 216 3.9E-33 T 22-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS03765 a2bf08646a5eae0ce5be9d0cde1c9598 234 Gene3D G3DSA:3.40.50.1860 1 112 8.2E-43 T 22-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS06915 7d25cfd57b04c744bd5377fc4688aa42 658 Gene3D G3DSA:3.30.70.1450 579 650 6.1E-19 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS06915 7d25cfd57b04c744bd5377fc4688aa42 658 Gene3D G3DSA:3.40.50.720 400 533 1.5E-32 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS06915 7d25cfd57b04c744bd5377fc4688aa42 658 SUPERFAMILY SSF51735 401 543 2.12E-30 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS06915 7d25cfd57b04c744bd5377fc4688aa42 658 PANTHER PTHR16254:SF17 6 559 4.5E-170 T 22-04-2016 HRM2_RS06915 7d25cfd57b04c744bd5377fc4688aa42 658 Pfam PF02254 TrkA-N domain 406 520 1.2E-22 T 22-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 HRM2_RS06915 7d25cfd57b04c744bd5377fc4688aa42 658 PANTHER PTHR16254 6 559 4.5E-170 T 22-04-2016 HRM2_RS06915 7d25cfd57b04c744bd5377fc4688aa42 658 Pfam PF00999 Sodium/hydrogen exchanger family 7 371 6.5E-65 T 22-04-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 HRM2_RS06915 7d25cfd57b04c744bd5377fc4688aa42 658 Pfam PF02080 TrkA-C domain 581 649 1.9E-13 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS06915 7d25cfd57b04c744bd5377fc4688aa42 658 SUPERFAMILY SSF116726 578 649 1.1E-16 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS16000 2732cc742f54752b5047d0a63a8288a1 656 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 41 50 - T 22-04-2016 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 HRM2_RS16000 2732cc742f54752b5047d0a63a8288a1 656 Gene3D G3DSA:4.10.80.40 549 572 1.0E-10 T 22-04-2016 HRM2_RS16000 2732cc742f54752b5047d0a63a8288a1 656 SUPERFAMILY SSF46977 460 652 6.41E-52 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 HRM2_RS16000 2732cc742f54752b5047d0a63a8288a1 656 SUPERFAMILY SSF51905 164 274 1.14E-54 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS16000 2732cc742f54752b5047d0a63a8288a1 656 SUPERFAMILY SSF51905 374 441 1.14E-54 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS16000 2732cc742f54752b5047d0a63a8288a1 656 SUPERFAMILY SSF51905 3 116 1.14E-54 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS16000 2732cc742f54752b5047d0a63a8288a1 656 Pfam PF00890 FAD binding domain 7 411 4.1E-119 T 22-04-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain HRM2_RS16000 2732cc742f54752b5047d0a63a8288a1 656 Gene3D G3DSA:3.50.50.60 366 431 4.0E-84 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS16000 2732cc742f54752b5047d0a63a8288a1 656 Gene3D G3DSA:3.50.50.60 4 257 4.0E-84 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS16000 2732cc742f54752b5047d0a63a8288a1 656 Pfam PF02910 Fumarate reductase flavoprotein C-term 468 598 1.9E-37 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 HRM2_RS16000 2732cc742f54752b5047d0a63a8288a1 656 SUPERFAMILY SSF56425 251 370 8.52E-39 T 22-04-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain HRM2_RS16000 2732cc742f54752b5047d0a63a8288a1 656 Gene3D G3DSA:1.20.58.100 440 548 6.4E-36 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 HRM2_RS16000 2732cc742f54752b5047d0a63a8288a1 656 PANTHER PTHR11632:SF5 136 591 4.0E-252 T 22-04-2016 HRM2_RS16000 2732cc742f54752b5047d0a63a8288a1 656 PANTHER PTHR11632:SF5 1 114 4.0E-252 T 22-04-2016 HRM2_RS16000 2732cc742f54752b5047d0a63a8288a1 656 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 598 8.3E-220 T 22-04-2016 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 HRM2_RS16000 2732cc742f54752b5047d0a63a8288a1 656 Gene3D G3DSA:3.90.700.10 258 365 1.2E-37 T 22-04-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain HRM2_RS16000 2732cc742f54752b5047d0a63a8288a1 656 PANTHER PTHR11632 136 591 4.0E-252 T 22-04-2016 HRM2_RS16000 2732cc742f54752b5047d0a63a8288a1 656 PANTHER PTHR11632 1 114 4.0E-252 T 22-04-2016 HRM2_RS07630 e2dab84bb56c75b32bfed735fe1936b8 336 SUPERFAMILY SSF53686 4 324 1.51E-76 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HRM2_RS07630 e2dab84bb56c75b32bfed735fe1936b8 336 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 12 315 1.9E-48 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HRM2_RS07630 e2dab84bb56c75b32bfed735fe1936b8 336 TIGRFAM TIGR01275 ACC_deam_rel: pyridoxal phosphate-dependent enzymes, D-cysteine desulfhydrase family 11 327 6.3E-91 T 22-04-2016 IPR005966 D-cysteine desulfhydrase GO:0003824 KEGG: 00270+4.4.1.15 HRM2_RS07630 e2dab84bb56c75b32bfed735fe1936b8 336 PIRSF PIRSF006278 1 333 1.1E-90 T 22-04-2016 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase HRM2_RS07630 e2dab84bb56c75b32bfed735fe1936b8 336 Gene3D G3DSA:3.40.50.1100 115 328 1.3E-61 T 22-04-2016 HRM2_RS07630 e2dab84bb56c75b32bfed735fe1936b8 336 PANTHER PTHR10314:SF105 2 316 1.0E-90 T 22-04-2016 HRM2_RS07630 e2dab84bb56c75b32bfed735fe1936b8 336 PANTHER PTHR10314 2 316 1.0E-90 T 22-04-2016 HRM2_RS07630 e2dab84bb56c75b32bfed735fe1936b8 336 Gene3D G3DSA:3.40.50.1100 20 114 5.2E-4 T 22-04-2016 HRM2_RS11150 b4d412ff2acdc18df1751541c1428836 439 PANTHER PTHR21090:SF5 13 372 1.5E-149 T 22-04-2016 HRM2_RS11150 b4d412ff2acdc18df1751541c1428836 439 PANTHER PTHR21090:SF5 393 438 1.5E-149 T 22-04-2016 HRM2_RS11150 b4d412ff2acdc18df1751541c1428836 439 Gene3D G3DSA:3.65.10.10 235 437 4.3E-68 T 22-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 HRM2_RS11150 b4d412ff2acdc18df1751541c1428836 439 SUPERFAMILY SSF55205 11 438 4.06E-116 T 22-04-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 HRM2_RS11150 b4d412ff2acdc18df1751541c1428836 439 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 13 434 6.9E-120 T 22-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 HRM2_RS11150 b4d412ff2acdc18df1751541c1428836 439 ProSitePatterns PS00885 EPSP synthase signature 2. 334 352 - T 22-04-2016 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS11150 b4d412ff2acdc18df1751541c1428836 439 ProSitePatterns PS00104 EPSP synthase signature 1. 86 100 - T 22-04-2016 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS11150 b4d412ff2acdc18df1751541c1428836 439 PIRSF PIRSF000505 1 439 6.2E-137 T 22-04-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS11150 b4d412ff2acdc18df1751541c1428836 439 PANTHER PTHR21090 13 372 1.5E-149 T 22-04-2016 HRM2_RS11150 b4d412ff2acdc18df1751541c1428836 439 PANTHER PTHR21090 393 438 1.5E-149 T 22-04-2016 HRM2_RS11150 b4d412ff2acdc18df1751541c1428836 439 Gene3D G3DSA:3.65.10.10 20 234 1.0E-54 T 22-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 HRM2_RS11150 b4d412ff2acdc18df1751541c1428836 439 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 14 438 2.9E-131 T 22-04-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS11150 b4d412ff2acdc18df1751541c1428836 439 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 8 439 31.076 T 22-04-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS13520 38a56e5ce14c6f0160a5f28ad4fa763c 531 SMART SM00382 26 238 4.4E-14 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS13520 38a56e5ce14c6f0160a5f28ad4fa763c 531 PANTHER PTHR19211 1 528 0.0 T 22-04-2016 HRM2_RS13520 38a56e5ce14c6f0160a5f28ad4fa763c 531 SUPERFAMILY SSF52540 295 514 3.39E-33 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13520 38a56e5ce14c6f0160a5f28ad4fa763c 531 PANTHER PTHR19211:SF38 1 528 0.0 T 22-04-2016 HRM2_RS13520 38a56e5ce14c6f0160a5f28ad4fa763c 531 SUPERFAMILY SSF52540 2 235 8.75E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13520 38a56e5ce14c6f0160a5f28ad4fa763c 531 Pfam PF00005 ABC transporter 335 465 1.9E-10 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS13520 38a56e5ce14c6f0160a5f28ad4fa763c 531 Pfam PF00005 ABC transporter 18 184 6.0E-21 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS13520 38a56e5ce14c6f0160a5f28ad4fa763c 531 Gene3D G3DSA:3.40.50.300 418 523 1.2E-28 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13520 38a56e5ce14c6f0160a5f28ad4fa763c 531 Gene3D G3DSA:3.40.50.300 310 382 1.2E-28 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13520 38a56e5ce14c6f0160a5f28ad4fa763c 531 Pfam PF12848 ABC transporter 224 304 4.1E-17 T 22-04-2016 IPR032781 ABC-transporter extension domain HRM2_RS13520 38a56e5ce14c6f0160a5f28ad4fa763c 531 Gene3D G3DSA:3.40.50.300 1 270 1.4E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13820 c9f54dc91202b39c4376557447445821 334 PIRSF PIRSF000149 1 333 6.3E-133 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS13820 c9f54dc91202b39c4376557447445821 334 Gene3D G3DSA:3.30.360.10 161 315 5.4E-73 T 22-04-2016 HRM2_RS13820 c9f54dc91202b39c4376557447445821 334 SUPERFAMILY SSF51735 3 168 2.58E-66 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS13820 c9f54dc91202b39c4376557447445821 334 PANTHER PTHR10836 3 330 2.2E-201 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS13820 c9f54dc91202b39c4376557447445821 334 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 152 2.2E-62 T 22-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS13820 c9f54dc91202b39c4376557447445821 334 SUPERFAMILY SSF55347 152 314 2.62E-70 T 22-04-2016 HRM2_RS13820 c9f54dc91202b39c4376557447445821 334 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 3.3E-135 T 22-04-2016 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS13820 c9f54dc91202b39c4376557447445821 334 Gene3D G3DSA:3.40.50.720 3 160 1.7E-76 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS13820 c9f54dc91202b39c4376557447445821 334 PANTHER PTHR10836:SF50 3 330 2.2E-201 T 22-04-2016 HRM2_RS13820 c9f54dc91202b39c4376557447445821 334 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 313 2.4E-65 T 22-04-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS13820 c9f54dc91202b39c4376557447445821 334 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 22-04-2016 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS13820 c9f54dc91202b39c4376557447445821 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 270 285 4.8E-40 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS13820 c9f54dc91202b39c4376557447445821 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 4.8E-40 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS13820 c9f54dc91202b39c4376557447445821 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 4.8E-40 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS13820 c9f54dc91202b39c4376557447445821 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 4.8E-40 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS13820 c9f54dc91202b39c4376557447445821 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 4.8E-40 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS13820 c9f54dc91202b39c4376557447445821 334 SMART SM00846 3 152 2.6E-96 T 22-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS19335 7a1fb83bf4d5a8b9223b1cc07a389f70 133 PANTHER PTHR33937:SF2 30 131 2.1E-14 T 22-04-2016 HRM2_RS19335 7a1fb83bf4d5a8b9223b1cc07a389f70 133 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 42 130 7.6E-12 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS19335 7a1fb83bf4d5a8b9223b1cc07a389f70 133 PANTHER PTHR33937 30 131 2.1E-14 T 22-04-2016 HRM2_RS19335 7a1fb83bf4d5a8b9223b1cc07a389f70 133 Gene3D G3DSA:3.30.420.130 22 132 4.8E-20 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS19335 7a1fb83bf4d5a8b9223b1cc07a389f70 133 SUPERFAMILY SSF53146 30 129 7.46E-18 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS08435 0b66dce10b2f30f74a37c069acae6906 204 Pfam PF13578 Methyltransferase domain 37 165 6.8E-19 T 22-04-2016 HRM2_RS08435 0b66dce10b2f30f74a37c069acae6906 204 Gene3D G3DSA:3.40.50.150 16 168 5.1E-8 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS08435 0b66dce10b2f30f74a37c069acae6906 204 SUPERFAMILY SSF53335 6 192 6.98E-7 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS04755 743932e778a37e7cbfed99a24e494815 352 Pfam PF00892 EamA-like transporter family 156 284 3.6E-10 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS04755 743932e778a37e7cbfed99a24e494815 352 Pfam PF00892 EamA-like transporter family 11 144 6.0E-14 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS04755 743932e778a37e7cbfed99a24e494815 352 SUPERFAMILY SSF103481 204 287 4.84E-8 T 22-04-2016 HRM2_RS04755 743932e778a37e7cbfed99a24e494815 352 PANTHER PTHR22911 11 312 1.8E-24 T 22-04-2016 HRM2_RS04755 743932e778a37e7cbfed99a24e494815 352 SUPERFAMILY SSF103481 62 147 4.32E-8 T 22-04-2016 HRM2_RS16690 1cc99301aa13563dd025b3010a0c3951 385 Gene3D G3DSA:3.40.50.2300 28 153 1.1E-36 T 22-04-2016 HRM2_RS16690 1cc99301aa13563dd025b3010a0c3951 385 Gene3D G3DSA:3.40.50.2300 307 361 1.1E-36 T 22-04-2016 HRM2_RS16690 1cc99301aa13563dd025b3010a0c3951 385 Gene3D G3DSA:3.40.50.2300 157 306 1.2E-28 T 22-04-2016 HRM2_RS16690 1cc99301aa13563dd025b3010a0c3951 385 PANTHER PTHR30483 30 379 4.3E-53 T 22-04-2016 HRM2_RS16690 1cc99301aa13563dd025b3010a0c3951 385 Pfam PF13458 Periplasmic binding protein 30 373 9.9E-47 T 22-04-2016 IPR028081 Leucine-binding protein domain HRM2_RS16690 1cc99301aa13563dd025b3010a0c3951 385 SUPERFAMILY SSF53822 30 380 5.05E-64 T 22-04-2016 IPR028082 Periplasmic binding protein-like I HRM2_RS16690 1cc99301aa13563dd025b3010a0c3951 385 PANTHER PTHR30483:SF20 30 379 4.3E-53 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HRM2_RS10860 53c7831c5d0c3d2b95522652a9ac7e9a 827 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 153 795 5.1E-90 T 22-04-2016 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 HRM2_RS10860 53c7831c5d0c3d2b95522652a9ac7e9a 827 Pfam PF00753 Metallo-beta-lactamase superfamily 563 646 2.2E-9 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS10860 53c7831c5d0c3d2b95522652a9ac7e9a 827 PANTHER PTHR30619 9 801 7.7E-145 T 22-04-2016 HRM2_RS10860 53c7831c5d0c3d2b95522652a9ac7e9a 827 Pfam PF03772 Competence protein 239 522 1.3E-59 T 22-04-2016 IPR004477 ComEC/Rec2-related protein HRM2_RS10860 53c7831c5d0c3d2b95522652a9ac7e9a 827 Pfam PF13567 Domain of unknown function (DUF4131) 18 192 2.0E-24 T 22-04-2016 IPR025405 Domain of unknown function DUF4131 HRM2_RS10860 53c7831c5d0c3d2b95522652a9ac7e9a 827 Gene3D G3DSA:3.60.15.10 549 790 2.0E-28 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS10860 53c7831c5d0c3d2b95522652a9ac7e9a 827 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 262 453 4.9E-28 T 22-04-2016 IPR004477 ComEC/Rec2-related protein HRM2_RS10860 53c7831c5d0c3d2b95522652a9ac7e9a 827 SUPERFAMILY SSF56281 554 810 1.3E-44 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS10860 53c7831c5d0c3d2b95522652a9ac7e9a 827 PANTHER PTHR30619:SF2 9 801 7.7E-145 T 22-04-2016 HRM2_RS10860 53c7831c5d0c3d2b95522652a9ac7e9a 827 SMART SM00849 566 768 5.2E-7 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS22580 f49bc5d4247bc08a778c97b07bc27031 265 PANTHER PTHR22939 36 259 6.1E-18 T 22-04-2016 HRM2_RS22580 f49bc5d4247bc08a778c97b07bc27031 265 Gene3D G3DSA:2.40.10.10 35 129 8.0E-18 T 22-04-2016 HRM2_RS22580 f49bc5d4247bc08a778c97b07bc27031 265 Pfam PF13365 Trypsin-like peptidase domain 63 225 1.2E-24 T 22-04-2016 HRM2_RS22580 f49bc5d4247bc08a778c97b07bc27031 265 SUPERFAMILY SSF50494 10 259 1.27E-35 T 22-04-2016 IPR009003 Peptidase S1, PA clan HRM2_RS22580 f49bc5d4247bc08a778c97b07bc27031 265 PANTHER PTHR22939:SF79 36 259 6.1E-18 T 22-04-2016 HRM2_RS22580 f49bc5d4247bc08a778c97b07bc27031 265 Gene3D G3DSA:2.40.10.10 130 260 4.9E-16 T 22-04-2016 HRM2_RS13160 a3595b56f605e3e601ec077d2901f22e 599 PANTHER PTHR11615 4 381 1.0E-117 T 22-04-2016 HRM2_RS13160 a3595b56f605e3e601ec077d2901f22e 599 PANTHER PTHR11615 402 580 1.0E-117 T 22-04-2016 HRM2_RS13160 a3595b56f605e3e601ec077d2901f22e 599 Pfam PF13187 4Fe-4S dicluster domain 151 209 7.6E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS13160 a3595b56f605e3e601ec077d2901f22e 599 Gene3D G3DSA:4.10.260.20 528 594 4.0E-25 T 22-04-2016 IPR003149 Iron hydrogenase, small subunit HRM2_RS13160 a3595b56f605e3e601ec077d2901f22e 599 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 88 126 2.1E-14 T 22-04-2016 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 HRM2_RS13160 a3595b56f605e3e601ec077d2901f22e 599 Gene3D G3DSA:3.40.50.1780 203 253 1.4E-73 T 22-04-2016 HRM2_RS13160 a3595b56f605e3e601ec077d2901f22e 599 Gene3D G3DSA:3.40.50.1780 305 436 1.4E-73 T 22-04-2016 HRM2_RS13160 a3595b56f605e3e601ec077d2901f22e 599 SUPERFAMILY SSF54292 4 78 1.15E-13 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 HRM2_RS13160 a3595b56f605e3e601ec077d2901f22e 599 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 230 515 3.3E-89 T 22-04-2016 IPR004108 Iron hydrogenase, large subunit, C-terminal HRM2_RS13160 a3595b56f605e3e601ec077d2901f22e 599 Pfam PF02256 Iron hydrogenase small subunit 529 580 4.3E-24 T 22-04-2016 IPR003149 Iron hydrogenase, small subunit HRM2_RS13160 a3595b56f605e3e601ec077d2901f22e 599 SUPERFAMILY SSF53920 194 578 4.32E-124 T 22-04-2016 IPR009016 Iron hydrogenase HRM2_RS13160 a3595b56f605e3e601ec077d2901f22e 599 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 4 80 5.8E-12 T 22-04-2016 HRM2_RS13160 a3595b56f605e3e601ec077d2901f22e 599 SUPERFAMILY SSF54862 80 214 1.26E-34 T 22-04-2016 HRM2_RS13160 a3595b56f605e3e601ec077d2901f22e 599 Gene3D G3DSA:3.10.20.30 6 56 8.8E-7 T 22-04-2016 IPR012675 Beta-grasp domain HRM2_RS13160 a3595b56f605e3e601ec077d2901f22e 599 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 195 206 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS13160 a3595b56f605e3e601ec077d2901f22e 599 Gene3D G3DSA:3.30.70.20 104 202 4.3E-14 T 22-04-2016 HRM2_RS13160 a3595b56f605e3e601ec077d2901f22e 599 SMART SM00902 522 581 8.5E-23 T 22-04-2016 IPR003149 Iron hydrogenase, small subunit HRM2_RS13160 a3595b56f605e3e601ec077d2901f22e 599 TIGRFAM TIGR02512 FeFe_hydrog_A: [FeFe] hydrogenase, group A 144 519 1.9E-156 T 22-04-2016 IPR013352 Iron hydrogenase, subset GO:0005506|GO:0008901|GO:0051536|GO:0055114 HRM2_RS13160 a3595b56f605e3e601ec077d2901f22e 599 SMART SM00929 87 127 3.0E-16 T 22-04-2016 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 HRM2_RS13160 a3595b56f605e3e601ec077d2901f22e 599 PANTHER PTHR11615:SF112 4 381 1.0E-117 T 22-04-2016 HRM2_RS13160 a3595b56f605e3e601ec077d2901f22e 599 PANTHER PTHR11615:SF112 402 580 1.0E-117 T 22-04-2016 HRM2_RS18590 7de3d4a9021ba4433f97aef034bda9d3 377 SMART SM00341 303 375 0.52 T 22-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 HRM2_RS18590 7de3d4a9021ba4433f97aef034bda9d3 377 SMART SM00341 210 290 3.3E-7 T 22-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 HRM2_RS18590 7de3d4a9021ba4433f97aef034bda9d3 377 PANTHER PTHR12124 1 365 3.5E-72 T 22-04-2016 HRM2_RS18590 7de3d4a9021ba4433f97aef034bda9d3 377 Pfam PF01612 3'-5' exonuclease 4 171 4.4E-41 T 22-04-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 HRM2_RS18590 7de3d4a9021ba4433f97aef034bda9d3 377 Gene3D G3DSA:3.30.420.10 3 185 5.2E-21 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS18590 7de3d4a9021ba4433f97aef034bda9d3 377 SMART SM00474 4 171 1.1E-40 T 22-04-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 HRM2_RS18590 7de3d4a9021ba4433f97aef034bda9d3 377 Gene3D G3DSA:1.10.150.80 312 374 1.0E-4 T 22-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 HRM2_RS18590 7de3d4a9021ba4433f97aef034bda9d3 377 Gene3D G3DSA:1.10.150.80 217 281 2.1E-6 T 22-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 HRM2_RS18590 7de3d4a9021ba4433f97aef034bda9d3 377 SUPERFAMILY SSF47819 307 374 2.13E-10 T 22-04-2016 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 HRM2_RS18590 7de3d4a9021ba4433f97aef034bda9d3 377 Pfam PF00570 HRDC domain 309 372 1.2E-9 T 22-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 HRM2_RS18590 7de3d4a9021ba4433f97aef034bda9d3 377 Pfam PF00570 HRDC domain 214 279 1.0E-10 T 22-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 HRM2_RS18590 7de3d4a9021ba4433f97aef034bda9d3 377 SUPERFAMILY SSF53098 3 209 7.42E-67 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS18590 7de3d4a9021ba4433f97aef034bda9d3 377 SUPERFAMILY SSF47819 196 298 3.05E-17 T 22-04-2016 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 HRM2_RS00390 56e1680aad7082ba7972dca1b09f0f73 553 PIRSF PIRSF000076 1 552 4.4E-258 T 22-04-2016 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS00390 56e1680aad7082ba7972dca1b09f0f73 553 Gene3D G3DSA:3.40.50.2030 229 380 1.3E-65 T 22-04-2016 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS00390 56e1680aad7082ba7972dca1b09f0f73 553 SUPERFAMILY SSF56821 1 550 2.14E-211 T 22-04-2016 IPR011254 Prismane-like GO:0003824|GO:0016491|GO:0055114 HRM2_RS00390 56e1680aad7082ba7972dca1b09f0f73 553 Gene3D G3DSA:1.20.1270.20 154 227 4.6E-26 T 22-04-2016 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS00390 56e1680aad7082ba7972dca1b09f0f73 553 PANTHER PTHR30109:SF0 1 551 2.1E-273 T 22-04-2016 HRM2_RS00390 56e1680aad7082ba7972dca1b09f0f73 553 Hamap MF_00069 Hydroxylamine reductase [hcp]. 1 551 23.735 T 22-04-2016 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS00390 56e1680aad7082ba7972dca1b09f0f73 553 Pfam PF03063 Prismane/CO dehydrogenase family 1 546 3.9E-174 T 22-04-2016 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS00390 56e1680aad7082ba7972dca1b09f0f73 553 Gene3D G3DSA:3.40.50.2030 381 549 2.4E-76 T 22-04-2016 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS00390 56e1680aad7082ba7972dca1b09f0f73 553 PANTHER PTHR30109 1 551 2.1E-273 T 22-04-2016 HRM2_RS00390 56e1680aad7082ba7972dca1b09f0f73 553 Gene3D G3DSA:1.20.1270.20 1 153 2.6E-43 T 22-04-2016 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS00390 56e1680aad7082ba7972dca1b09f0f73 553 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 1 549 6.0E-226 T 22-04-2016 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS02240 b6b5c892e2c606e3df10c6db07d90d9e 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.3E-20 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS02240 b6b5c892e2c606e3df10c6db07d90d9e 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.3E-20 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS02240 b6b5c892e2c606e3df10c6db07d90d9e 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 1.3E-20 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS02240 b6b5c892e2c606e3df10c6db07d90d9e 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.3E-20 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS02240 b6b5c892e2c606e3df10c6db07d90d9e 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 1.3E-20 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS02240 b6b5c892e2c606e3df10c6db07d90d9e 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.3E-20 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS02240 b6b5c892e2c606e3df10c6db07d90d9e 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 1.3E-5 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS02240 b6b5c892e2c606e3df10c6db07d90d9e 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.3E-5 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS02240 b6b5c892e2c606e3df10c6db07d90d9e 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.3E-5 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS02240 b6b5c892e2c606e3df10c6db07d90d9e 272 Gene3D G3DSA:3.40.50.720 2 258 1.7E-49 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS02240 b6b5c892e2c606e3df10c6db07d90d9e 272 PANTHER PTHR24322:SF639 10 140 3.0E-19 T 22-04-2016 HRM2_RS02240 b6b5c892e2c606e3df10c6db07d90d9e 272 SUPERFAMILY SSF51735 5 259 4.52E-48 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS02240 b6b5c892e2c606e3df10c6db07d90d9e 272 PANTHER PTHR24322 162 194 3.0E-19 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS02240 b6b5c892e2c606e3df10c6db07d90d9e 272 PANTHER PTHR24322 10 140 3.0E-19 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS02240 b6b5c892e2c606e3df10c6db07d90d9e 272 PANTHER PTHR24322:SF639 162 194 3.0E-19 T 22-04-2016 HRM2_RS02240 b6b5c892e2c606e3df10c6db07d90d9e 272 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 257 4.6E-32 T 22-04-2016 HRM2_RS22150 5ed03b5ba7e2e28bb1c0c9f25e04ba19 291 PANTHER PTHR22981 1 291 1.2E-140 T 22-04-2016 HRM2_RS22150 5ed03b5ba7e2e28bb1c0c9f25e04ba19 291 SUPERFAMILY SSF51735 3 162 1.48E-48 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS22150 5ed03b5ba7e2e28bb1c0c9f25e04ba19 291 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 162 3.8E-50 T 22-04-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 HRM2_RS22150 5ed03b5ba7e2e28bb1c0c9f25e04ba19 291 PANTHER PTHR22981:SF65 1 291 1.2E-140 T 22-04-2016 HRM2_RS22150 5ed03b5ba7e2e28bb1c0c9f25e04ba19 291 SUPERFAMILY SSF48179 163 288 5.21E-39 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HRM2_RS22150 5ed03b5ba7e2e28bb1c0c9f25e04ba19 291 Gene3D G3DSA:1.10.1040.10 164 289 1.4E-42 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HRM2_RS22150 5ed03b5ba7e2e28bb1c0c9f25e04ba19 291 PIRSF PIRSF000103 1 291 4.2E-70 T 22-04-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 HRM2_RS22150 5ed03b5ba7e2e28bb1c0c9f25e04ba19 291 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 284 1.0E-33 T 22-04-2016 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 HRM2_RS22150 5ed03b5ba7e2e28bb1c0c9f25e04ba19 291 Gene3D G3DSA:3.40.50.720 1 163 8.5E-54 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS11440 1b20c825419b2b8fd6fb59f98e56ab47 350 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 320 2.3E-96 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS11440 1b20c825419b2b8fd6fb59f98e56ab47 350 PANTHER PTHR10366 3 348 8.8E-162 T 22-04-2016 HRM2_RS11440 1b20c825419b2b8fd6fb59f98e56ab47 350 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 4 335 1.6E-144 T 22-04-2016 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 HRM2_RS11440 1b20c825419b2b8fd6fb59f98e56ab47 350 Gene3D G3DSA:3.40.50.720 1 187 1.8E-62 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS11440 1b20c825419b2b8fd6fb59f98e56ab47 350 PANTHER PTHR10366:SF41 3 348 8.8E-162 T 22-04-2016 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 HRM2_RS11440 1b20c825419b2b8fd6fb59f98e56ab47 350 Gene3D G3DSA:3.90.25.10 188 345 8.9E-55 T 22-04-2016 HRM2_RS11440 1b20c825419b2b8fd6fb59f98e56ab47 350 SUPERFAMILY SSF51735 1 332 3.94E-93 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS16985 d930d8b5c7dc7f7f3f0e73047de7df96 774 Gene3D G3DSA:1.10.287.950 485 689 3.2E-54 T 22-04-2016 HRM2_RS16985 d930d8b5c7dc7f7f3f0e73047de7df96 774 SMART SM00283 470 717 3.9E-72 T 22-04-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HRM2_RS16985 d930d8b5c7dc7f7f3f0e73047de7df96 774 PANTHER PTHR32089:SF63 452 720 3.4E-74 T 22-04-2016 HRM2_RS16985 d930d8b5c7dc7f7f3f0e73047de7df96 774 PANTHER PTHR32089 452 720 3.4E-74 T 22-04-2016 HRM2_RS16985 d930d8b5c7dc7f7f3f0e73047de7df96 774 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 535 714 1.1E-51 T 22-04-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HRM2_RS16985 d930d8b5c7dc7f7f3f0e73047de7df96 774 SUPERFAMILY SSF58104 462 718 1.57E-61 T 22-04-2016 HRM2_RS16985 d930d8b5c7dc7f7f3f0e73047de7df96 774 Pfam PF12729 Four helix bundle sensory module for signal transduction 3 130 2.0E-6 T 22-04-2016 IPR024478 4HB MCP domain HRM2_RS05925 ecddb70a7ec20e40ae25856320cc5160 186 Gene3D G3DSA:1.10.260.40 11 109 2.0E-13 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS05925 ecddb70a7ec20e40ae25856320cc5160 186 SUPERFAMILY SSF51182 77 184 2.41E-27 T 22-04-2016 IPR011051 RmlC-like cupin domain HRM2_RS05925 ecddb70a7ec20e40ae25856320cc5160 186 Gene3D G3DSA:2.60.120.10 110 185 7.2E-25 T 22-04-2016 IPR014710 RmlC-like jelly roll fold HRM2_RS05925 ecddb70a7ec20e40ae25856320cc5160 186 PANTHER PTHR10245:SF28 10 185 9.9E-28 T 22-04-2016 HRM2_RS05925 ecddb70a7ec20e40ae25856320cc5160 186 SUPERFAMILY SSF47413 10 74 5.36E-11 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS05925 ecddb70a7ec20e40ae25856320cc5160 186 PANTHER PTHR10245 10 185 9.9E-28 T 22-04-2016 HRM2_RS05925 ecddb70a7ec20e40ae25856320cc5160 186 Pfam PF07883 Cupin domain 116 184 2.9E-15 T 22-04-2016 IPR013096 Cupin 2, conserved barrel HRM2_RS05925 ecddb70a7ec20e40ae25856320cc5160 186 SMART SM00530 14 69 1.6E-6 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS23910 d3b3676c1203c07a93f1ce0828667301 189 PIRSF PIRSF036893 1 180 5.3E-39 T 22-04-2016 IPR022271 Lipocalin, ApoD type HRM2_RS23910 d3b3676c1203c07a93f1ce0828667301 189 Gene3D G3DSA:2.40.128.20 7 171 8.7E-51 T 22-04-2016 IPR012674 Calycin HRM2_RS23910 d3b3676c1203c07a93f1ce0828667301 189 PRINTS PR01171 Bacterial lipocalin signature 131 142 3.2E-35 T 22-04-2016 IPR002446 Lipocalin, bacterial GO:0005215 HRM2_RS23910 d3b3676c1203c07a93f1ce0828667301 189 PRINTS PR01171 Bacterial lipocalin signature 115 123 3.2E-35 T 22-04-2016 IPR002446 Lipocalin, bacterial GO:0005215 HRM2_RS23910 d3b3676c1203c07a93f1ce0828667301 189 PRINTS PR01171 Bacterial lipocalin signature 158 168 3.2E-35 T 22-04-2016 IPR002446 Lipocalin, bacterial GO:0005215 HRM2_RS23910 d3b3676c1203c07a93f1ce0828667301 189 PRINTS PR01171 Bacterial lipocalin signature 64 73 3.2E-35 T 22-04-2016 IPR002446 Lipocalin, bacterial GO:0005215 HRM2_RS23910 d3b3676c1203c07a93f1ce0828667301 189 PRINTS PR01171 Bacterial lipocalin signature 45 61 3.2E-35 T 22-04-2016 IPR002446 Lipocalin, bacterial GO:0005215 HRM2_RS23910 d3b3676c1203c07a93f1ce0828667301 189 PRINTS PR01171 Bacterial lipocalin signature 98 112 3.2E-35 T 22-04-2016 IPR002446 Lipocalin, bacterial GO:0005215 HRM2_RS23910 d3b3676c1203c07a93f1ce0828667301 189 PRINTS PR01171 Bacterial lipocalin signature 28 42 3.2E-35 T 22-04-2016 IPR002446 Lipocalin, bacterial GO:0005215 HRM2_RS23910 d3b3676c1203c07a93f1ce0828667301 189 ProSitePatterns PS00213 Lipocalin signature. 27 40 - T 22-04-2016 IPR022272 Lipocalin family conserved site HRM2_RS23910 d3b3676c1203c07a93f1ce0828667301 189 PANTHER PTHR10612 15 170 7.5E-48 T 22-04-2016 HRM2_RS23910 d3b3676c1203c07a93f1ce0828667301 189 Pfam PF08212 Lipocalin-like domain 29 168 2.5E-42 T 22-04-2016 IPR000566 Lipocalin/cytosolic fatty-acid binding domain HRM2_RS23910 d3b3676c1203c07a93f1ce0828667301 189 SUPERFAMILY SSF50814 5 172 6.23E-48 T 22-04-2016 IPR011038 Calycin-like HRM2_RS20005 70251183c21ecc66cd8b8b4f364a83e0 619 Pfam PF13361 UvrD-like helicase C-terminal domain 269 598 3.2E-58 T 22-04-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 HRM2_RS20005 70251183c21ecc66cd8b8b4f364a83e0 619 PANTHER PTHR11070:SF7 1 616 7.9E-155 T 22-04-2016 HRM2_RS20005 70251183c21ecc66cd8b8b4f364a83e0 619 Gene3D G3DSA:3.40.50.300 2 266 1.0E-72 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20005 70251183c21ecc66cd8b8b4f364a83e0 619 Gene3D G3DSA:1.10.486.10 380 520 2.0E-27 T 22-04-2016 HRM2_RS20005 70251183c21ecc66cd8b8b4f364a83e0 619 Pfam PF00580 UvrD/REP helicase N-terminal domain 3 263 1.1E-58 T 22-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 HRM2_RS20005 70251183c21ecc66cd8b8b4f364a83e0 619 SUPERFAMILY SSF52540 2 616 3.36E-136 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20005 70251183c21ecc66cd8b8b4f364a83e0 619 Gene3D G3DSA:3.40.50.300 533 616 1.4E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20005 70251183c21ecc66cd8b8b4f364a83e0 619 Gene3D G3DSA:3.40.50.300 272 379 1.4E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20005 70251183c21ecc66cd8b8b4f364a83e0 619 PANTHER PTHR11070 1 616 7.9E-155 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 HRM2_RS01990 8beb1568d6c30b96f3fb3c4d9929db7b 200 SUPERFAMILY SSF58014 38 131 2.09E-25 T 22-04-2016 HRM2_RS01990 8beb1568d6c30b96f3fb3c4d9929db7b 200 SUPERFAMILY SSF51064 136 190 2.75E-17 T 22-04-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 HRM2_RS01990 8beb1568d6c30b96f3fb3c4d9929db7b 200 Hamap MF_01151 Protein GrpE [grpE]. 4 190 20.219 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 HRM2_RS01990 8beb1568d6c30b96f3fb3c4d9929db7b 200 Gene3D G3DSA:2.30.22.10 135 190 1.0E-23 T 22-04-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 HRM2_RS01990 8beb1568d6c30b96f3fb3c4d9929db7b 200 PANTHER PTHR21237 38 193 7.8E-54 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 HRM2_RS01990 8beb1568d6c30b96f3fb3c4d9929db7b 200 ProSitePatterns PS01071 grpE protein signature. 145 188 - T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 HRM2_RS01990 8beb1568d6c30b96f3fb3c4d9929db7b 200 Pfam PF01025 GrpE 29 190 1.2E-49 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 HRM2_RS01990 8beb1568d6c30b96f3fb3c4d9929db7b 200 Gene3D G3DSA:3.90.20.20 36 131 2.6E-28 T 22-04-2016 IPR013805 GrpE nucleotide exchange factor, coiled-coil HRM2_RS01990 8beb1568d6c30b96f3fb3c4d9929db7b 200 PRINTS PR00773 GrpE protein signature 87 102 1.8E-26 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 HRM2_RS01990 8beb1568d6c30b96f3fb3c4d9929db7b 200 PRINTS PR00773 GrpE protein signature 169 188 1.8E-26 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 HRM2_RS01990 8beb1568d6c30b96f3fb3c4d9929db7b 200 PRINTS PR00773 GrpE protein signature 142 157 1.8E-26 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 HRM2_RS01990 8beb1568d6c30b96f3fb3c4d9929db7b 200 PRINTS PR00773 GrpE protein signature 59 75 1.8E-26 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 HRM2_RS25080 9f9cf9c5ed93a6d45e652edd842f6207 742 SMART SM00091 168 235 1.3E-9 T 22-04-2016 IPR000014 PAS domain HRM2_RS25080 9f9cf9c5ed93a6d45e652edd842f6207 742 SUPERFAMILY SSF55785 160 279 8.72E-15 T 22-04-2016 IPR000014 PAS domain HRM2_RS25080 9f9cf9c5ed93a6d45e652edd842f6207 742 Pfam PF00158 Sigma-54 interaction domain 434 601 2.0E-61 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS25080 9f9cf9c5ed93a6d45e652edd842f6207 742 SUPERFAMILY SSF46689 684 740 3.63E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS25080 9f9cf9c5ed93a6d45e652edd842f6207 742 PANTHER PTHR32071 403 740 2.3E-129 T 22-04-2016 HRM2_RS25080 9f9cf9c5ed93a6d45e652edd842f6207 742 Gene3D G3DSA:1.10.10.60 657 740 8.5E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS25080 9f9cf9c5ed93a6d45e652edd842f6207 742 Pfam PF02954 Bacterial regulatory protein, Fis family 701 738 6.4E-11 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS25080 9f9cf9c5ed93a6d45e652edd842f6207 742 Gene3D G3DSA:1.10.8.60 606 656 2.4E-17 T 22-04-2016 HRM2_RS25080 9f9cf9c5ed93a6d45e652edd842f6207 742 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 704 721 1.1E-7 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS25080 9f9cf9c5ed93a6d45e652edd842f6207 742 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 721 741 1.1E-7 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS25080 9f9cf9c5ed93a6d45e652edd842f6207 742 Gene3D G3DSA:3.30.450.20 160 279 5.1E-17 T 22-04-2016 HRM2_RS25080 9f9cf9c5ed93a6d45e652edd842f6207 742 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 458 471 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS25080 9f9cf9c5ed93a6d45e652edd842f6207 742 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 520 535 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS25080 9f9cf9c5ed93a6d45e652edd842f6207 742 Pfam PF13426 PAS domain 304 399 0.013 T 22-04-2016 IPR000014 PAS domain HRM2_RS25080 9f9cf9c5ed93a6d45e652edd842f6207 742 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 645 654 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS25080 9f9cf9c5ed93a6d45e652edd842f6207 742 Gene3D G3DSA:3.40.50.300 429 605 3.5E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS25080 9f9cf9c5ed93a6d45e652edd842f6207 742 SMART SM00382 454 601 7.9E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS25080 9f9cf9c5ed93a6d45e652edd842f6207 742 SUPERFAMILY SSF55785 278 398 1.92E-10 T 22-04-2016 IPR000014 PAS domain HRM2_RS25080 9f9cf9c5ed93a6d45e652edd842f6207 742 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 166 288 2.1E-18 T 22-04-2016 IPR000014 PAS domain HRM2_RS25080 9f9cf9c5ed93a6d45e652edd842f6207 742 SUPERFAMILY SSF52540 433 664 4.03E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS25080 9f9cf9c5ed93a6d45e652edd842f6207 742 Gene3D G3DSA:3.30.450.20 284 400 4.8E-12 T 22-04-2016 HRM2_RS25080 9f9cf9c5ed93a6d45e652edd842f6207 742 Pfam PF08447 PAS fold 191 259 1.5E-6 T 22-04-2016 IPR013655 PAS fold-3 GO:0005515 HRM2_RS20205 e231e3a473ed4348577b101d52d004d3 237 Gene3D G3DSA:3.30.70.20 3 80 1.6E-31 T 22-04-2016 HRM2_RS20205 e231e3a473ed4348577b101d52d004d3 237 Gene3D G3DSA:3.30.70.20 134 181 1.6E-31 T 22-04-2016 HRM2_RS20205 e231e3a473ed4348577b101d52d004d3 237 PANTHER PTHR11938 1 228 2.9E-33 T 22-04-2016 HRM2_RS20205 e231e3a473ed4348577b101d52d004d3 237 SUPERFAMILY SSF54862 3 207 7.74E-43 T 22-04-2016 HRM2_RS20205 e231e3a473ed4348577b101d52d004d3 237 Gene3D G3DSA:3.30.70.20 81 133 2.8E-14 T 22-04-2016 HRM2_RS20205 e231e3a473ed4348577b101d52d004d3 237 Pfam PF13247 4Fe-4S dicluster domain 65 163 1.6E-37 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS20205 e231e3a473ed4348577b101d52d004d3 237 PANTHER PTHR11938:SF88 1 228 2.9E-33 T 22-04-2016 HRM2_RS02640 984257927c84d5e58015859631659ea6 208 SUPERFAMILY SSF53271 3 206 1.08E-63 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like HRM2_RS02640 984257927c84d5e58015859631659ea6 208 PANTHER PTHR10285 1 197 1.1E-84 T 22-04-2016 HRM2_RS02640 984257927c84d5e58015859631659ea6 208 Pfam PF14681 Uracil phosphoribosyltransferase 5 207 4.6E-62 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like HRM2_RS02640 984257927c84d5e58015859631659ea6 208 Gene3D G3DSA:3.40.50.2020 2 208 1.7E-72 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like HRM2_RS02640 984257927c84d5e58015859631659ea6 208 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 208 1.5E-85 T 22-04-2016 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183|UniPathway: UPA00574 HRM2_RS02640 984257927c84d5e58015859631659ea6 208 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 208 43.07 T 22-04-2016 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183|UniPathway: UPA00574 HRM2_RS00145 9dd6ee25af3feb13fe3c42ce2c77b25d 260 Gene3D G3DSA:1.10.3720.10 9 248 3.3E-38 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS00145 9dd6ee25af3feb13fe3c42ce2c77b25d 260 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 258 2.2E-12 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS00145 9dd6ee25af3feb13fe3c42ce2c77b25d 260 PANTHER PTHR30193:SF20 8 259 1.3E-33 T 22-04-2016 HRM2_RS00145 9dd6ee25af3feb13fe3c42ce2c77b25d 260 SUPERFAMILY SSF161098 9 251 9.35E-40 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS00145 9dd6ee25af3feb13fe3c42ce2c77b25d 260 PANTHER PTHR30193 8 259 1.3E-33 T 22-04-2016 HRM2_RS14120 9ecc5aec0e5ef19a5bf13251e66df01b 838 Pfam PF11739 Dicarboxylate transport 621 783 1.4E-12 T 22-04-2016 IPR021730 Dicarboxylate transport HRM2_RS02310 7ca78e1c0c3ba5170b3d5bf6454dd982 302 PANTHER PTHR13767:SF2 3 258 2.0E-93 T 22-04-2016 HRM2_RS02310 7ca78e1c0c3ba5170b3d5bf6454dd982 302 SUPERFAMILY SSF55120 3 227 4.32E-70 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS02310 7ca78e1c0c3ba5170b3d5bf6454dd982 302 PANTHER PTHR13767 3 258 2.0E-93 T 22-04-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS02310 7ca78e1c0c3ba5170b3d5bf6454dd982 302 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 2 300 16.193 T 22-04-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS02310 7ca78e1c0c3ba5170b3d5bf6454dd982 302 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 176 231 1.8E-14 T 22-04-2016 IPR032819 tRNA pseudouridylate synthase B, C-terminal HRM2_RS02310 7ca78e1c0c3ba5170b3d5bf6454dd982 302 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 3 214 3.6E-61 T 22-04-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS02310 7ca78e1c0c3ba5170b3d5bf6454dd982 302 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 24 175 2.1E-46 T 22-04-2016 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 HRM2_RS05500 20b6cbd5197e69d3a7b6c5f7ceb49a59 167 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 7 65 9.3E-19 T 22-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HRM2_RS05500 20b6cbd5197e69d3a7b6c5f7ceb49a59 167 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 7 161 7.1E-59 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 HRM2_RS05500 20b6cbd5197e69d3a7b6c5f7ceb49a59 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 53 77 3.3E-47 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 HRM2_RS05500 20b6cbd5197e69d3a7b6c5f7ceb49a59 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 89 105 3.3E-47 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 HRM2_RS05500 20b6cbd5197e69d3a7b6c5f7ceb49a59 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 116 138 3.3E-47 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 HRM2_RS05500 20b6cbd5197e69d3a7b6c5f7ceb49a59 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 6 24 3.3E-47 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 HRM2_RS05500 20b6cbd5197e69d3a7b6c5f7ceb49a59 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 24 45 3.3E-47 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 HRM2_RS05500 20b6cbd5197e69d3a7b6c5f7ceb49a59 167 Gene3D G3DSA:3.40.50.620 5 161 3.8E-52 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS05500 20b6cbd5197e69d3a7b6c5f7ceb49a59 167 PANTHER PTHR21342:SF1 1 161 3.3E-75 T 22-04-2016 HRM2_RS05500 20b6cbd5197e69d3a7b6c5f7ceb49a59 167 SUPERFAMILY SSF52374 6 154 6.91E-43 T 22-04-2016 HRM2_RS05500 20b6cbd5197e69d3a7b6c5f7ceb49a59 167 Pfam PF01467 Cytidylyltransferase-like 9 137 7.0E-22 T 22-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HRM2_RS05500 20b6cbd5197e69d3a7b6c5f7ceb49a59 167 PANTHER PTHR21342 1 161 3.3E-75 T 22-04-2016 HRM2_RS05500 20b6cbd5197e69d3a7b6c5f7ceb49a59 167 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 6 162 34.579 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 HRM2_RS17365 da23cf4e018fdc6be4921c2da6c9c683 472 SUPERFAMILY SSF52540 85 356 3.73E-89 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17365 da23cf4e018fdc6be4921c2da6c9c683 472 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 341 350 - T 22-04-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS17365 da23cf4e018fdc6be4921c2da6c9c683 472 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 8 80 7.0E-20 T 22-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS17365 da23cf4e018fdc6be4921c2da6c9c683 472 SUPERFAMILY SSF47917 353 468 1.44E-52 T 22-04-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS17365 da23cf4e018fdc6be4921c2da6c9c683 472 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 137 350 1.1E-63 T 22-04-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS17365 da23cf4e018fdc6be4921c2da6c9c683 472 Gene3D G3DSA:2.40.10.170 3 82 3.1E-31 T 22-04-2016 HRM2_RS17365 da23cf4e018fdc6be4921c2da6c9c683 472 PANTHER PTHR15184:SF8 1 470 0.0 T 22-04-2016 HRM2_RS17365 da23cf4e018fdc6be4921c2da6c9c683 472 Gene3D G3DSA:1.10.1140.10 354 469 2.1E-53 T 22-04-2016 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS17365 da23cf4e018fdc6be4921c2da6c9c683 472 PANTHER PTHR15184 1 470 0.0 T 22-04-2016 HRM2_RS17365 da23cf4e018fdc6be4921c2da6c9c683 472 SUPERFAMILY SSF50615 4 82 2.88E-26 T 22-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS17365 da23cf4e018fdc6be4921c2da6c9c683 472 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 5 468 4.6E-245 T 22-04-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS17365 da23cf4e018fdc6be4921c2da6c9c683 472 SMART SM00382 149 335 6.8E-4 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS17365 da23cf4e018fdc6be4921c2da6c9c683 472 Hamap MF_01347 ATP synthase subunit beta [atpB]. 3 468 55.88 T 22-04-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS17365 da23cf4e018fdc6be4921c2da6c9c683 472 Gene3D G3DSA:3.40.50.300 84 352 3.8E-104 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01515 b428603f0656b24d088dc3784176d49f 155 Pfam PF01575 MaoC like domain 12 133 8.3E-28 T 22-04-2016 IPR002539 MaoC-like domain HRM2_RS01515 b428603f0656b24d088dc3784176d49f 155 SUPERFAMILY SSF54637 8 149 5.97E-35 T 22-04-2016 IPR029069 HotDog domain HRM2_RS01515 b428603f0656b24d088dc3784176d49f 155 PANTHER PTHR13078 5 146 1.5E-31 T 22-04-2016 HRM2_RS01515 b428603f0656b24d088dc3784176d49f 155 Gene3D G3DSA:3.10.129.10 9 151 7.1E-34 T 22-04-2016 IPR029069 HotDog domain HRM2_RS11260 bcb483bceaae6e6dd4c296e6e2858e40 434 PANTHER PTHR32071 101 433 6.5E-143 T 22-04-2016 HRM2_RS11260 bcb483bceaae6e6dd4c296e6e2858e40 434 SUPERFAMILY SSF52540 120 364 7.22E-70 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11260 bcb483bceaae6e6dd4c296e6e2858e40 434 Gene3D G3DSA:3.30.450.20 2 102 2.0E-12 T 22-04-2016 HRM2_RS11260 bcb483bceaae6e6dd4c296e6e2858e40 434 Pfam PF08448 PAS fold 2 103 1.2E-8 T 22-04-2016 IPR013656 PAS fold-4 HRM2_RS11260 bcb483bceaae6e6dd4c296e6e2858e40 434 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 333 342 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS11260 bcb483bceaae6e6dd4c296e6e2858e40 434 Gene3D G3DSA:1.10.10.60 393 429 2.4E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS11260 bcb483bceaae6e6dd4c296e6e2858e40 434 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 2 110 5.6E-9 T 22-04-2016 IPR000014 PAS domain HRM2_RS11260 bcb483bceaae6e6dd4c296e6e2858e40 434 Gene3D G3DSA:3.40.50.300 116 291 1.1E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11260 bcb483bceaae6e6dd4c296e6e2858e40 434 SUPERFAMILY SSF55785 2 95 2.62E-12 T 22-04-2016 IPR000014 PAS domain HRM2_RS11260 bcb483bceaae6e6dd4c296e6e2858e40 434 Gene3D G3DSA:1.10.8.60 294 365 9.0E-21 T 22-04-2016 HRM2_RS11260 bcb483bceaae6e6dd4c296e6e2858e40 434 Pfam PF00158 Sigma-54 interaction domain 120 286 7.5E-68 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS11260 bcb483bceaae6e6dd4c296e6e2858e40 434 SMART SM00382 140 287 2.2E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS11260 bcb483bceaae6e6dd4c296e6e2858e40 434 SUPERFAMILY SSF46689 334 432 2.15E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS11260 bcb483bceaae6e6dd4c296e6e2858e40 434 Pfam PF02954 Bacterial regulatory protein, Fis family 393 430 4.5E-12 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS11260 bcb483bceaae6e6dd4c296e6e2858e40 434 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 413 433 8.0E-6 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS11260 bcb483bceaae6e6dd4c296e6e2858e40 434 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 396 413 8.0E-6 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS01575 ff16f98c01d5c93a585bf287037f1f3e 429 TIGRFAM TIGR03378 glycerol3P_GlpB: glycerol-3-phosphate dehydrogenase, anaerobic, B subunit 10 418 4.8E-62 T 22-04-2016 IPR009158 Glycerol-3-phosphate dehydrogenase, GlpB subunit GO:0004368|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|UniPathway: UPA00618 HRM2_RS01575 ff16f98c01d5c93a585bf287037f1f3e 429 Gene3D G3DSA:3.50.50.60 254 414 2.7E-19 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS01575 ff16f98c01d5c93a585bf287037f1f3e 429 Gene3D G3DSA:3.50.50.60 7 68 2.7E-19 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS01575 ff16f98c01d5c93a585bf287037f1f3e 429 Gene3D G3DSA:3.50.50.60 145 184 2.7E-19 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS01575 ff16f98c01d5c93a585bf287037f1f3e 429 SUPERFAMILY SSF51905 4 52 6.66E-22 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS01575 ff16f98c01d5c93a585bf287037f1f3e 429 SUPERFAMILY SSF51905 157 214 6.66E-22 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS01575 ff16f98c01d5c93a585bf287037f1f3e 429 SUPERFAMILY SSF51905 254 421 6.66E-22 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS01575 ff16f98c01d5c93a585bf287037f1f3e 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 372 394 3.6E-7 T 22-04-2016 HRM2_RS01575 ff16f98c01d5c93a585bf287037f1f3e 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 3.6E-7 T 22-04-2016 HRM2_RS01575 ff16f98c01d5c93a585bf287037f1f3e 429 Pfam PF00890 FAD binding domain 10 405 3.2E-18 T 22-04-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain HRM2_RS01575 ff16f98c01d5c93a585bf287037f1f3e 429 PIRSF PIRSF000141 7 427 1.4E-88 T 22-04-2016 IPR009158 Glycerol-3-phosphate dehydrogenase, GlpB subunit GO:0004368|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|UniPathway: UPA00618 HRM2_RS16285 5ec220c79460b14e13e6bb33f14dd95d 382 Gene3D G3DSA:3.80.30.20 5 204 4.3E-37 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe HRM2_RS16285 5ec220c79460b14e13e6bb33f14dd95d 382 SUPERFAMILY SSF102114 6 376 4.84E-106 T 22-04-2016 HRM2_RS16285 5ec220c79460b14e13e6bb33f14dd95d 382 Pfam PF04055 Radical SAM superfamily 9 173 3.3E-20 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS16285 5ec220c79460b14e13e6bb33f14dd95d 382 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 6 348 4.1E-79 T 22-04-2016 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00071+1.3.99.-|KEGG: 00280+1.3.99.-|KEGG: 00281+1.3.99.-|KEGG: 00362+1.3.99.-|KEGG: 00626+1.3.99.-|KEGG: 00930+1.3.99.- HRM2_RS16285 5ec220c79460b14e13e6bb33f14dd95d 382 PANTHER PTHR13932 6 379 6.1E-122 T 22-04-2016 HRM2_RS16285 5ec220c79460b14e13e6bb33f14dd95d 382 SMART SM00729 4 221 5.2E-53 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS10835 9d3fdd0b95e0c3889670d1e6f0a0961c 328 PIRSF PIRSF004532 4 323 9.0E-128 T 22-04-2016 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 HRM2_RS10835 9d3fdd0b95e0c3889670d1e6f0a0961c 328 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 6 313 9.7E-134 T 22-04-2016 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 HRM2_RS10835 9d3fdd0b95e0c3889670d1e6f0a0961c 328 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 5 317 2.1E-108 T 22-04-2016 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 HRM2_RS10835 9d3fdd0b95e0c3889670d1e6f0a0961c 328 SUPERFAMILY SSF56655 4 316 1.28E-100 T 22-04-2016 HRM2_RS10835 9d3fdd0b95e0c3889670d1e6f0a0961c 328 Gene3D G3DSA:3.30.540.10 4 176 2.0E-56 T 22-04-2016 HRM2_RS10835 9d3fdd0b95e0c3889670d1e6f0a0961c 328 Gene3D G3DSA:3.30.540.10 177 317 9.3E-34 T 22-04-2016 HRM2_RS10835 9d3fdd0b95e0c3889670d1e6f0a0961c 328 PANTHER PTHR30447 1 327 1.5E-161 T 22-04-2016 HRM2_RS10835 9d3fdd0b95e0c3889670d1e6f0a0961c 328 PANTHER PTHR30447:SF0 1 327 1.5E-161 T 22-04-2016 HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 Pfam PF00689 Cation transporting ATPase, C-terminus 837 1008 7.4E-33 T 22-04-2016 IPR006068 Cation-transporting P-type ATPase, C-terminal HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 SUPERFAMILY SSF56784 448 468 4.7E-53 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 SUPERFAMILY SSF56784 608 856 4.7E-53 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 Pfam PF00702 haloacid dehalogenase-like hydrolase 446 766 5.1E-21 T 22-04-2016 HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 721 837 5.1E-31 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 342 471 4.1E-21 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 Pfam PF00690 Cation transporter/ATPase, N-terminus 129 197 2.2E-12 T 22-04-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 SUPERFAMILY SSF81665 351 444 1.07E-101 T 22-04-2016 HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 SUPERFAMILY SSF81665 802 1014 1.07E-101 T 22-04-2016 HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 SUPERFAMILY SSF81665 127 240 1.07E-101 T 22-04-2016 HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 SUPERFAMILY SSF81653 240 346 8.11E-32 T 22-04-2016 HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 Gene3D G3DSA:2.70.150.10 139 181 2.9E-40 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 Gene3D G3DSA:2.70.150.10 235 346 2.9E-40 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 PANTHER PTHR24093 36 1019 1.6E-259 T 22-04-2016 HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 Pfam PF00122 E1-E2 ATPase 207 441 6.3E-63 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 SMART SM00831 128 202 7.9E-15 T 22-04-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 784 809 2.7E-15 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 752 768 2.7E-15 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 611 629 2.7E-15 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 724 740 2.7E-15 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 SUPERFAMILY SSF81660 456 660 1.5E-36 T 22-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 776 788 3.1E-38 T 22-04-2016 HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 287 301 3.1E-38 T 22-04-2016 HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 752 771 3.1E-38 T 22-04-2016 HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 649 660 3.1E-38 T 22-04-2016 HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 450 464 3.1E-38 T 22-04-2016 HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 671 681 3.1E-38 T 22-04-2016 HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 Gene3D G3DSA:1.20.1110.10 182 234 2.9E-91 T 22-04-2016 IPR023298 P-type ATPase, transmembrane domain HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 Gene3D G3DSA:1.20.1110.10 721 1012 2.9E-91 T 22-04-2016 IPR023298 P-type ATPase, transmembrane domain HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 452 458 - T 22-04-2016 IPR018303 P-type ATPase, phosphorylation site HRM2_RS20390 a26debd70cbd3ba42cc863831ed57b4d 1055 Gene3D G3DSA:3.40.1110.10 441 656 6.0E-45 T 22-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 HRM2_RS18400 b9dcce2fe7c758fb1fe4061b1b7e52c3 571 PANTHER PTHR30046 1 569 5.8E-129 T 22-04-2016 HRM2_RS18400 b9dcce2fe7c758fb1fe4061b1b7e52c3 571 PANTHER PTHR30046:SF0 1 569 5.8E-129 T 22-04-2016 HRM2_RS18400 b9dcce2fe7c758fb1fe4061b1b7e52c3 571 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 8 468 2.4E-105 T 22-04-2016 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 HRM2_RS18400 b9dcce2fe7c758fb1fe4061b1b7e52c3 571 Pfam PF01514 Secretory protein of YscJ/FliF family 27 214 5.0E-68 T 22-04-2016 IPR006182 Secretory protein YscJ/FliF HRM2_RS18400 b9dcce2fe7c758fb1fe4061b1b7e52c3 571 PIRSF PIRSF004862 1 569 7.1E-129 T 22-04-2016 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 HRM2_RS18400 b9dcce2fe7c758fb1fe4061b1b7e52c3 571 Pfam PF08345 Flagellar M-ring protein C-terminal 253 421 1.3E-35 T 22-04-2016 IPR013556 Flagellar M-ring C-terminal HRM2_RS18400 b9dcce2fe7c758fb1fe4061b1b7e52c3 571 PRINTS PR01009 Flagellar M-ring protein signature 190 208 1.1E-32 T 22-04-2016 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 HRM2_RS18400 b9dcce2fe7c758fb1fe4061b1b7e52c3 571 PRINTS PR01009 Flagellar M-ring protein signature 149 163 1.1E-32 T 22-04-2016 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 HRM2_RS18400 b9dcce2fe7c758fb1fe4061b1b7e52c3 571 PRINTS PR01009 Flagellar M-ring protein signature 341 365 1.1E-32 T 22-04-2016 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 HRM2_RS18400 b9dcce2fe7c758fb1fe4061b1b7e52c3 571 PRINTS PR01009 Flagellar M-ring protein signature 117 135 1.1E-32 T 22-04-2016 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 HRM2_RS18400 b9dcce2fe7c758fb1fe4061b1b7e52c3 571 PRINTS PR01009 Flagellar M-ring protein signature 266 284 1.1E-32 T 22-04-2016 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 HRM2_RS22610 5a6a176f0c9e2787d92ce1f86e942f08 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 504 518 6.0E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS22610 5a6a176f0c9e2787d92ce1f86e942f08 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 533 551 6.0E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS22610 5a6a176f0c9e2787d92ce1f86e942f08 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 522 532 6.0E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS22610 5a6a176f0c9e2787d92ce1f86e942f08 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 557 570 6.0E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS22610 5a6a176f0c9e2787d92ce1f86e942f08 580 SUPERFAMILY SSF55874 415 571 4.58E-33 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS22610 5a6a176f0c9e2787d92ce1f86e942f08 580 Pfam PF00672 HAMP domain 265 331 3.5E-12 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS22610 5a6a176f0c9e2787d92ce1f86e942f08 580 Gene3D G3DSA:3.30.565.10 427 569 2.3E-33 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS22610 5a6a176f0c9e2787d92ce1f86e942f08 580 SMART SM00387 465 573 2.8E-27 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS22610 5a6a176f0c9e2787d92ce1f86e942f08 580 Gene3D G3DSA:1.10.287.130 343 421 1.5E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS22610 5a6a176f0c9e2787d92ce1f86e942f08 580 SMART SM00304 283 335 2.1E-9 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS22610 5a6a176f0c9e2787d92ce1f86e942f08 580 Pfam PF00512 His Kinase A (phospho-acceptor) domain 346 421 6.7E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS22610 5a6a176f0c9e2787d92ce1f86e942f08 580 SMART SM00388 345 425 4.0E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS22610 5a6a176f0c9e2787d92ce1f86e942f08 580 PANTHER PTHR24423 277 579 3.1E-59 T 22-04-2016 HRM2_RS22610 5a6a176f0c9e2787d92ce1f86e942f08 580 PANTHER PTHR24423 4 28 3.1E-59 T 22-04-2016 HRM2_RS22610 5a6a176f0c9e2787d92ce1f86e942f08 580 PANTHER PTHR24423 85 158 3.1E-59 T 22-04-2016 HRM2_RS22610 5a6a176f0c9e2787d92ce1f86e942f08 580 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 466 571 7.4E-18 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS22610 5a6a176f0c9e2787d92ce1f86e942f08 580 SUPERFAMILY SSF47384 341 423 2.55E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS22610 5a6a176f0c9e2787d92ce1f86e942f08 580 SUPERFAMILY SSF158472 284 332 1.28E-7 T 22-04-2016 HRM2_RS20865 387e722336f7b77d2e1e6a7ba08f545d 270 PANTHER PTHR30371 4 260 1.1E-96 T 22-04-2016 HRM2_RS20865 387e722336f7b77d2e1e6a7ba08f545d 270 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 4 241 19.578 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HRM2_RS20865 387e722336f7b77d2e1e6a7ba08f545d 270 PANTHER PTHR30371:SF0 4 260 1.1E-96 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HRM2_RS20865 387e722336f7b77d2e1e6a7ba08f545d 270 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 86 104 1.8E-38 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HRM2_RS20865 387e722336f7b77d2e1e6a7ba08f545d 270 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 9 36 1.8E-38 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HRM2_RS20865 387e722336f7b77d2e1e6a7ba08f545d 270 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 155 183 1.8E-38 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HRM2_RS20865 387e722336f7b77d2e1e6a7ba08f545d 270 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 104 130 1.8E-38 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HRM2_RS20865 387e722336f7b77d2e1e6a7ba08f545d 270 Pfam PF00902 Sec-independent protein translocase protein (TatC) 12 222 3.8E-73 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HRM2_RS20865 387e722336f7b77d2e1e6a7ba08f545d 270 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 11 227 2.8E-68 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HRM2_RS16180 8b88552a064247e6a578c18a6d3c0cd2 334 PANTHER PTHR10366:SF460 8 262 1.3E-106 T 22-04-2016 HRM2_RS16180 8b88552a064247e6a578c18a6d3c0cd2 334 PANTHER PTHR10366 285 330 1.3E-106 T 22-04-2016 HRM2_RS16180 8b88552a064247e6a578c18a6d3c0cd2 334 PANTHER PTHR10366 8 262 1.3E-106 T 22-04-2016 HRM2_RS16180 8b88552a064247e6a578c18a6d3c0cd2 334 Pfam PF01073 3-beta hydroxysteroid dehydrogenase/isomerase family 10 253 8.9E-58 T 22-04-2016 IPR002225 3-beta hydroxysteroid dehydrogenase/isomerase GO:0003854|GO:0006694|GO:0016616|GO:0055114 HRM2_RS16180 8b88552a064247e6a578c18a6d3c0cd2 334 Gene3D G3DSA:3.40.50.720 8 323 6.3E-61 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS16180 8b88552a064247e6a578c18a6d3c0cd2 334 SUPERFAMILY SSF51735 7 329 2.99E-69 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS16180 8b88552a064247e6a578c18a6d3c0cd2 334 PANTHER PTHR10366:SF460 285 330 1.3E-106 T 22-04-2016 HRM2_RS05040 971b62118f471857736e8ebeb04f65eb 663 SUPERFAMILY SSF58104 340 640 4.84E-60 T 22-04-2016 HRM2_RS05040 971b62118f471857736e8ebeb04f65eb 663 Gene3D G3DSA:3.30.450.20 201 272 5.6E-11 T 22-04-2016 HRM2_RS05040 971b62118f471857736e8ebeb04f65eb 663 SMART SM00283 387 662 5.1E-47 T 22-04-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HRM2_RS05040 971b62118f471857736e8ebeb04f65eb 663 Pfam PF00672 HAMP domain 299 366 4.0E-9 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS05040 971b62118f471857736e8ebeb04f65eb 663 PANTHER PTHR32089 7 663 7.9E-95 T 22-04-2016 HRM2_RS05040 971b62118f471857736e8ebeb04f65eb 663 Gene3D G3DSA:1.10.287.950 410 619 1.1E-45 T 22-04-2016 HRM2_RS05040 971b62118f471857736e8ebeb04f65eb 663 SMART SM00304 318 372 9.4E-6 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS05040 971b62118f471857736e8ebeb04f65eb 663 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 473 661 2.4E-33 T 22-04-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HRM2_RS20445 e102ea0f3cc046522f68c3cbb1be5b7e 171 PANTHER PTHR11106 2 163 3.7E-70 T 22-04-2016 HRM2_RS20445 e102ea0f3cc046522f68c3cbb1be5b7e 171 Gene3D G3DSA:3.40.220.10 2 168 3.2E-59 T 22-04-2016 HRM2_RS20445 e102ea0f3cc046522f68c3cbb1be5b7e 171 SUPERFAMILY SSF52949 3 168 1.19E-56 T 22-04-2016 HRM2_RS20445 e102ea0f3cc046522f68c3cbb1be5b7e 171 SMART SM00506 3 136 6.2E-52 T 22-04-2016 IPR002589 Macro domain HRM2_RS20445 e102ea0f3cc046522f68c3cbb1be5b7e 171 Pfam PF01661 Macro domain 20 135 1.8E-41 T 22-04-2016 IPR002589 Macro domain HRM2_RS03320 c21ed4fd81127ab206ded3e24fca403e 66 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 4 48 3.2E-21 T 22-04-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 HRM2_RS03320 c21ed4fd81127ab206ded3e24fca403e 66 PANTHER PTHR33162 1 63 5.6E-18 T 22-04-2016 HRM2_RS03320 c21ed4fd81127ab206ded3e24fca403e 66 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 2 63 20.21 T 22-04-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 HRM2_RS03320 c21ed4fd81127ab206ded3e24fca403e 66 Pfam PF02416 mttA/Hcf106 family 5 55 3.1E-20 T 22-04-2016 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 HRM2_RS01280 758c25233b2fee2b444c7b103d9ed350 995 Pfam PF05193 Peptidase M16 inactive domain 213 398 2.5E-17 T 22-04-2016 IPR007863 Peptidase M16, C-terminal HRM2_RS01280 758c25233b2fee2b444c7b103d9ed350 995 Pfam PF08367 Peptidase M16C associated 473 719 1.3E-65 T 22-04-2016 IPR013578 Peptidase M16C associated GO:0006508 HRM2_RS01280 758c25233b2fee2b444c7b103d9ed350 995 SUPERFAMILY SSF63411 12 250 1.72E-49 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HRM2_RS01280 758c25233b2fee2b444c7b103d9ed350 995 SUPERFAMILY SSF63411 795 962 2.2E-34 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HRM2_RS01280 758c25233b2fee2b444c7b103d9ed350 995 PANTHER PTHR11851 6 397 2.6E-290 T 22-04-2016 HRM2_RS01280 758c25233b2fee2b444c7b103d9ed350 995 PANTHER PTHR11851 413 975 2.6E-290 T 22-04-2016 HRM2_RS01280 758c25233b2fee2b444c7b103d9ed350 995 SUPERFAMILY SSF63411 268 530 4.22E-52 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HRM2_RS01280 758c25233b2fee2b444c7b103d9ed350 995 Gene3D G3DSA:3.30.830.10 25 250 7.8E-44 T 22-04-2016 IPR011237 Peptidase M16 domain GO:0046872 HRM2_RS01280 758c25233b2fee2b444c7b103d9ed350 995 PANTHER PTHR11851:SF150 6 397 2.6E-290 T 22-04-2016 HRM2_RS01280 758c25233b2fee2b444c7b103d9ed350 995 PANTHER PTHR11851:SF150 413 975 2.6E-290 T 22-04-2016 HRM2_RS01280 758c25233b2fee2b444c7b103d9ed350 995 Pfam PF00675 Insulinase (Peptidase family M16) 61 146 2.4E-8 T 22-04-2016 IPR011765 Peptidase M16, N-terminal HRM2_RS01280 758c25233b2fee2b444c7b103d9ed350 995 SMART SM01264 473 719 5.5E-89 T 22-04-2016 IPR013578 Peptidase M16C associated GO:0006508 HRM2_RS01280 758c25233b2fee2b444c7b103d9ed350 995 SUPERFAMILY SSF63411 529 782 2.64E-54 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HRM2_RS12510 2004291bd54f5660a2147164b7ea1960 563 Gene3D G3DSA:3.10.400.10 7 177 1.0E-57 T 22-04-2016 HRM2_RS12510 2004291bd54f5660a2147164b7ea1960 563 SUPERFAMILY SSF52374 164 383 1.25E-64 T 22-04-2016 HRM2_RS12510 2004291bd54f5660a2147164b7ea1960 563 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 7 378 8.1E-111 T 22-04-2016 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: REACT_13433|UniPathway: UPA00140 HRM2_RS12510 2004291bd54f5660a2147164b7ea1960 563 SUPERFAMILY SSF88697 7 163 2.49E-44 T 22-04-2016 IPR015947 PUA-like domain HRM2_RS12510 2004291bd54f5660a2147164b7ea1960 563 PANTHER PTHR11055 8 389 3.0E-149 T 22-04-2016 HRM2_RS12510 2004291bd54f5660a2147164b7ea1960 563 SUPERFAMILY SSF52540 387 559 5.14E-32 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12510 2004291bd54f5660a2147164b7ea1960 563 PANTHER PTHR11055:SF2 8 389 3.0E-149 T 22-04-2016 HRM2_RS12510 2004291bd54f5660a2147164b7ea1960 563 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 387 554 2.8E-50 T 22-04-2016 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: REACT_13433|UniPathway: UPA00140 HRM2_RS12510 2004291bd54f5660a2147164b7ea1960 563 Gene3D G3DSA:3.40.50.300 387 563 1.7E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12510 2004291bd54f5660a2147164b7ea1960 563 Pfam PF14306 PUA-like domain 7 157 3.5E-46 T 22-04-2016 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|UniPathway: UPA00140 HRM2_RS12510 2004291bd54f5660a2147164b7ea1960 563 Gene3D G3DSA:3.40.50.620 178 386 5.2E-72 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS12510 2004291bd54f5660a2147164b7ea1960 563 Pfam PF01747 ATP-sulfurylase 166 380 2.8E-74 T 22-04-2016 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|UniPathway: UPA00140 HRM2_RS12510 2004291bd54f5660a2147164b7ea1960 563 Pfam PF01583 Adenylylsulphate kinase 388 543 5.5E-56 T 22-04-2016 HRM2_RS01805 b55138c3c2c077701f1c0de6bb20e245 189 SUPERFAMILY SSF52821 46 154 2.23E-24 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS01805 b55138c3c2c077701f1c0de6bb20e245 189 Pfam PF00581 Rhodanese-like domain 60 147 7.4E-10 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS01805 b55138c3c2c077701f1c0de6bb20e245 189 SMART SM00450 55 151 4.7E-12 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS01805 b55138c3c2c077701f1c0de6bb20e245 189 Gene3D G3DSA:3.40.250.10 45 153 1.7E-22 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS09675 8ebe69c1e2faec881eb3cb9f26f4a9ec 515 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 116 499 1.2E-74 T 22-04-2016 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 HRM2_RS09675 8ebe69c1e2faec881eb3cb9f26f4a9ec 515 Pfam PF12161 HsdM N-terminal domain 8 135 4.8E-27 T 22-04-2016 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain HRM2_RS09675 8ebe69c1e2faec881eb3cb9f26f4a9ec 515 SUPERFAMILY SSF53335 319 514 7.79E-140 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS09675 8ebe69c1e2faec881eb3cb9f26f4a9ec 515 SUPERFAMILY SSF53335 8 290 7.79E-140 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS09675 8ebe69c1e2faec881eb3cb9f26f4a9ec 515 PANTHER PTHR30408 74 501 1.7E-117 T 22-04-2016 HRM2_RS09675 8ebe69c1e2faec881eb3cb9f26f4a9ec 515 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 331 355 1.1E-23 T 22-04-2016 HRM2_RS09675 8ebe69c1e2faec881eb3cb9f26f4a9ec 515 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 195 209 1.1E-23 T 22-04-2016 HRM2_RS09675 8ebe69c1e2faec881eb3cb9f26f4a9ec 515 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 276 288 1.1E-23 T 22-04-2016 HRM2_RS09675 8ebe69c1e2faec881eb3cb9f26f4a9ec 515 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 171 187 1.1E-23 T 22-04-2016 HRM2_RS09675 8ebe69c1e2faec881eb3cb9f26f4a9ec 515 PANTHER PTHR30408:SF4 74 501 1.7E-117 T 22-04-2016 HRM2_RS09675 8ebe69c1e2faec881eb3cb9f26f4a9ec 515 Pfam PF02384 N-6 DNA Methylase 148 480 7.7E-106 T 22-04-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 HRM2_RS09675 8ebe69c1e2faec881eb3cb9f26f4a9ec 515 Gene3D G3DSA:3.40.50.150 173 436 1.0E-42 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS06095 7165459d31e4d4c6a435df9d61e81706 504 Pfam PF03129 Anticodon binding domain 303 402 2.4E-9 T 22-04-2016 IPR004154 Anticodon-binding HRM2_RS06095 7165459d31e4d4c6a435df9d61e81706 504 Gene3D G3DSA:3.40.50.800 297 420 1.6E-29 T 22-04-2016 IPR004154 Anticodon-binding HRM2_RS06095 7165459d31e4d4c6a435df9d61e81706 504 Gene3D G3DSA:3.30.110.30 425 503 1.3E-28 T 22-04-2016 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 HRM2_RS06095 7165459d31e4d4c6a435df9d61e81706 504 Gene3D G3DSA:3.30.930.10 13 296 3.0E-100 T 22-04-2016 HRM2_RS06095 7165459d31e4d4c6a435df9d61e81706 504 SUPERFAMILY SSF55681 15 290 8.53E-68 T 22-04-2016 HRM2_RS06095 7165459d31e4d4c6a435df9d61e81706 504 PANTHER PTHR11451 14 478 2.0E-210 T 22-04-2016 HRM2_RS06095 7165459d31e4d4c6a435df9d61e81706 504 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 13 504 1.6E-149 T 22-04-2016 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 HRM2_RS06095 7165459d31e4d4c6a435df9d61e81706 504 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 118 281 5.9E-12 T 22-04-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS06095 7165459d31e4d4c6a435df9d61e81706 504 Hamap MF_01571 Proline--tRNA ligase [proS]. 10 504 42.398 T 22-04-2016 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 HRM2_RS06095 7165459d31e4d4c6a435df9d61e81706 504 PANTHER PTHR11451:SF6 14 478 2.0E-210 T 22-04-2016 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 HRM2_RS06095 7165459d31e4d4c6a435df9d61e81706 504 SMART SM00946 431 504 5.6E-27 T 22-04-2016 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 HRM2_RS06095 7165459d31e4d4c6a435df9d61e81706 504 SUPERFAMILY SSF64586 426 504 4.12E-21 T 22-04-2016 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 HRM2_RS06095 7165459d31e4d4c6a435df9d61e81706 504 SUPERFAMILY SSF52954 292 422 4.25E-24 T 22-04-2016 IPR004154 Anticodon-binding HRM2_RS06095 7165459d31e4d4c6a435df9d61e81706 504 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 448 504 5.1E-21 T 22-04-2016 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 HRM2_RS14820 710ba81cd79b790b0a2496b230e73640 577 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 95 242 2.8E-6 T 22-04-2016 HRM2_RS17185 03e9d9664c27e4ff9b784a0c0d30adfb 224 Pfam PF07589 PEP-CTERM motif 187 210 3.2E-8 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain HRM2_RS17185 03e9d9664c27e4ff9b784a0c0d30adfb 224 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 188 212 1.4E-5 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain HRM2_RS04850 6c4576a8ea74e29317e6f5444b9bc179 253 Gene3D G3DSA:3.40.190.10 213 250 1.0E-12 T 22-04-2016 HRM2_RS04850 6c4576a8ea74e29317e6f5444b9bc179 253 Gene3D G3DSA:3.40.190.10 25 106 1.0E-12 T 22-04-2016 HRM2_RS04850 6c4576a8ea74e29317e6f5444b9bc179 253 Pfam PF13531 Bacterial extracellular solute-binding protein 26 250 2.0E-43 T 22-04-2016 HRM2_RS04850 6c4576a8ea74e29317e6f5444b9bc179 253 SUPERFAMILY SSF53850 25 250 1.71E-65 T 22-04-2016 HRM2_RS04850 6c4576a8ea74e29317e6f5444b9bc179 253 PANTHER PTHR30632:SF0 1 250 1.3E-58 T 22-04-2016 HRM2_RS04850 6c4576a8ea74e29317e6f5444b9bc179 253 Gene3D G3DSA:3.40.190.10 107 212 2.8E-42 T 22-04-2016 HRM2_RS04850 6c4576a8ea74e29317e6f5444b9bc179 253 PANTHER PTHR30632 1 250 1.3E-58 T 22-04-2016 HRM2_RS04850 6c4576a8ea74e29317e6f5444b9bc179 253 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 31 249 7.1E-62 T 22-04-2016 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 HRM2_RS04850 6c4576a8ea74e29317e6f5444b9bc179 253 PIRSF PIRSF004846 1 253 2.2E-70 T 22-04-2016 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 HRM2_RS00420 a67aba360cff95b19b63afa72633c55f 174 PIRSF PIRSF000013 3 173 3.6E-18 T 22-04-2016 IPR024717 Denitrification system component NapC/NirT/NrfH GO:0016021|GO:0019333|GO:0020037 HRM2_RS00420 a67aba360cff95b19b63afa72633c55f 174 SUPERFAMILY SSF48695 5 171 2.62E-22 T 22-04-2016 IPR011031 Multihaem cytochrome HRM2_RS00420 a67aba360cff95b19b63afa72633c55f 174 Gene3D G3DSA:1.10.3820.10 3 169 3.7E-20 T 22-04-2016 HRM2_RS00420 a67aba360cff95b19b63afa72633c55f 174 Pfam PF03264 NapC/NirT cytochrome c family, N-terminal region 4 166 4.0E-35 T 22-04-2016 IPR005126 NapC/NirT cytochrome c, N-terminal HRM2_RS00420 a67aba360cff95b19b63afa72633c55f 174 PANTHER PTHR30333 8 169 1.7E-19 T 22-04-2016 HRM2_RS21715 a4f670f954d407830ea5dd4caa52d9c7 101 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 1 74 3.5E-30 T 22-04-2016 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 HRM2_RS21715 a4f670f954d407830ea5dd4caa52d9c7 101 SUPERFAMILY SSF47413 3 85 5.07E-26 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS21715 a4f670f954d407830ea5dd4caa52d9c7 101 Pfam PF01381 Helix-turn-helix 8 61 1.2E-11 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS21715 a4f670f954d407830ea5dd4caa52d9c7 101 Gene3D G3DSA:1.10.260.40 1 87 4.2E-31 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS21715 a4f670f954d407830ea5dd4caa52d9c7 101 PANTHER PTHR36924:SF1 1 88 1.9E-33 T 22-04-2016 HRM2_RS21715 a4f670f954d407830ea5dd4caa52d9c7 101 SMART SM00530 7 62 1.2E-9 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS21715 a4f670f954d407830ea5dd4caa52d9c7 101 PANTHER PTHR36924 1 88 1.9E-33 T 22-04-2016 HRM2_RS13295 0af1a07f4edb279b06527cd14b694903 423 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 418 5.6E-210 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS13295 0af1a07f4edb279b06527cd14b694903 423 PRINTS PR00148 Enolase signature 311 322 2.3E-46 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS13295 0af1a07f4edb279b06527cd14b694903 423 PRINTS PR00148 Enolase signature 107 123 2.3E-46 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS13295 0af1a07f4edb279b06527cd14b694903 423 PRINTS PR00148 Enolase signature 334 348 2.3E-46 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS13295 0af1a07f4edb279b06527cd14b694903 423 PRINTS PR00148 Enolase signature 37 51 2.3E-46 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS13295 0af1a07f4edb279b06527cd14b694903 423 PRINTS PR00148 Enolase signature 363 380 2.3E-46 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS13295 0af1a07f4edb279b06527cd14b694903 423 PRINTS PR00148 Enolase signature 161 174 2.3E-46 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS13295 0af1a07f4edb279b06527cd14b694903 423 SMART SM01193 4 134 2.3E-94 T 22-04-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 HRM2_RS13295 0af1a07f4edb279b06527cd14b694903 423 SUPERFAMILY SSF51604 138 415 3.54E-126 T 22-04-2016 IPR029065 Enolase C-terminal domain-like HRM2_RS13295 0af1a07f4edb279b06527cd14b694903 423 PIRSF PIRSF001400 1 421 2.8E-192 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS13295 0af1a07f4edb279b06527cd14b694903 423 Gene3D G3DSA:3.20.20.120 128 420 1.3E-134 T 22-04-2016 IPR029065 Enolase C-terminal domain-like HRM2_RS13295 0af1a07f4edb279b06527cd14b694903 423 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 417 9.2E-128 T 22-04-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 HRM2_RS13295 0af1a07f4edb279b06527cd14b694903 423 Gene3D G3DSA:3.30.390.10 4 125 7.4E-55 T 22-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HRM2_RS13295 0af1a07f4edb279b06527cd14b694903 423 PANTHER PTHR11902 1 417 5.0E-256 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS13295 0af1a07f4edb279b06527cd14b694903 423 Pfam PF03952 Enolase, N-terminal domain 4 134 1.4E-60 T 22-04-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 HRM2_RS13295 0af1a07f4edb279b06527cd14b694903 423 Hamap MF_00318 Enolase [eno]. 2 411 45.374 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS13295 0af1a07f4edb279b06527cd14b694903 423 ProSitePatterns PS00164 Enolase signature. 334 347 - T 22-04-2016 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS13295 0af1a07f4edb279b06527cd14b694903 423 SUPERFAMILY SSF54826 3 138 1.47E-57 T 22-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HRM2_RS13295 0af1a07f4edb279b06527cd14b694903 423 SMART SM01192 139 419 5.3E-212 T 22-04-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 HRM2_RS22325 73099d5a0069da404661101a2e7d259a 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 9.5E-36 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS22325 73099d5a0069da404661101a2e7d259a 381 PANTHER PTHR10909:SF305 1 380 4.9E-147 T 22-04-2016 HRM2_RS22325 73099d5a0069da404661101a2e7d259a 381 SUPERFAMILY SSF56645 3 239 3.14E-72 T 22-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 HRM2_RS22325 73099d5a0069da404661101a2e7d259a 381 SUPERFAMILY SSF47203 226 378 1.18E-52 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS22325 73099d5a0069da404661101a2e7d259a 381 Gene3D G3DSA:1.20.140.10 216 378 8.7E-62 T 22-04-2016 HRM2_RS22325 73099d5a0069da404661101a2e7d259a 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 215 7.3E-21 T 22-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 HRM2_RS22325 73099d5a0069da404661101a2e7d259a 381 PANTHER PTHR10909 1 380 4.9E-147 T 22-04-2016 HRM2_RS22325 73099d5a0069da404661101a2e7d259a 381 Gene3D G3DSA:2.40.110.10 121 215 3.6E-34 T 22-04-2016 HRM2_RS22325 73099d5a0069da404661101a2e7d259a 381 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 22-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 HRM2_RS22325 73099d5a0069da404661101a2e7d259a 381 Gene3D G3DSA:1.10.540.10 1 119 7.2E-40 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS22325 73099d5a0069da404661101a2e7d259a 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 375 2.3E-49 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS18565 ebacf993f06e676a8a3d96a3c390ee9d 1333 SMART SM00847 467 566 2.1E-28 T 22-04-2016 IPR007502 Helicase-associated domain GO:0004386 HRM2_RS18565 ebacf993f06e676a8a3d96a3c390ee9d 1333 Gene3D G3DSA:3.40.50.300 285 418 3.4E-12 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18565 ebacf993f06e676a8a3d96a3c390ee9d 1333 PANTHER PTHR18934 76 621 1.8E-280 T 22-04-2016 HRM2_RS18565 ebacf993f06e676a8a3d96a3c390ee9d 1333 PANTHER PTHR18934 766 894 1.8E-280 T 22-04-2016 HRM2_RS18565 ebacf993f06e676a8a3d96a3c390ee9d 1333 PANTHER PTHR18934 644 729 1.8E-280 T 22-04-2016 HRM2_RS18565 ebacf993f06e676a8a3d96a3c390ee9d 1333 Pfam PF11898 Domain of unknown function (DUF3418) 740 1327 1.7E-146 T 22-04-2016 IPR024590 RNA helicase HrpA, C-terminal HRM2_RS18565 ebacf993f06e676a8a3d96a3c390ee9d 1333 Pfam PF00271 Helicase conserved C-terminal domain 286 406 2.8E-11 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS18565 ebacf993f06e676a8a3d96a3c390ee9d 1333 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 609 724 1.7E-15 T 22-04-2016 IPR011709 Domain of unknown function DUF1605 HRM2_RS18565 ebacf993f06e676a8a3d96a3c390ee9d 1333 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 11 1327 0.0 T 22-04-2016 IPR010222 RNA helicase HrpA GO:0004004 HRM2_RS18565 ebacf993f06e676a8a3d96a3c390ee9d 1333 SMART SM00490 308 407 1.2E-13 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS18565 ebacf993f06e676a8a3d96a3c390ee9d 1333 Pfam PF04408 Helicase associated domain (HA2) 471 565 9.6E-14 T 22-04-2016 IPR007502 Helicase-associated domain GO:0004386 HRM2_RS18565 ebacf993f06e676a8a3d96a3c390ee9d 1333 Gene3D G3DSA:3.40.50.300 76 234 5.6E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18565 ebacf993f06e676a8a3d96a3c390ee9d 1333 SMART SM00487 75 259 5.6E-28 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS18565 ebacf993f06e676a8a3d96a3c390ee9d 1333 SUPERFAMILY SSF52540 80 586 7.8E-99 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18565 ebacf993f06e676a8a3d96a3c390ee9d 1333 PANTHER PTHR18934:SF109 76 621 1.8E-280 T 22-04-2016 HRM2_RS18565 ebacf993f06e676a8a3d96a3c390ee9d 1333 PANTHER PTHR18934:SF109 766 894 1.8E-280 T 22-04-2016 HRM2_RS18565 ebacf993f06e676a8a3d96a3c390ee9d 1333 PANTHER PTHR18934:SF109 644 729 1.8E-280 T 22-04-2016 HRM2_RS07085 a36b8580d79ca1de95fe6045350f7022 707 Gene3D G3DSA:2.40.40.20 537 697 2.5E-30 T 22-04-2016 HRM2_RS07085 a36b8580d79ca1de95fe6045350f7022 707 Gene3D G3DSA:3.40.228.10 138 322 4.2E-58 T 22-04-2016 HRM2_RS07085 a36b8580d79ca1de95fe6045350f7022 707 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 6 59 1.3E-15 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS07085 a36b8580d79ca1de95fe6045350f7022 707 Gene3D G3DSA:2.20.25.90 4 63 3.9E-21 T 22-04-2016 HRM2_RS07085 a36b8580d79ca1de95fe6045350f7022 707 SMART SM00926 5 59 1.9E-18 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS07085 a36b8580d79ca1de95fe6045350f7022 707 SUPERFAMILY SSF53706 7 579 1.44E-149 T 22-04-2016 HRM2_RS07085 a36b8580d79ca1de95fe6045350f7022 707 Pfam PF00384 Molybdopterin oxidoreductase 62 484 1.1E-48 T 22-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 HRM2_RS07085 a36b8580d79ca1de95fe6045350f7022 707 PANTHER PTHR11615:SF139 1 697 2.0E-100 T 22-04-2016 HRM2_RS07085 a36b8580d79ca1de95fe6045350f7022 707 SUPERFAMILY SSF50692 531 697 4.97E-35 T 22-04-2016 IPR009010 Aspartate decarboxylase-like domain HRM2_RS07085 a36b8580d79ca1de95fe6045350f7022 707 Gene3D G3DSA:3.40.50.740 64 137 9.0E-53 T 22-04-2016 HRM2_RS07085 a36b8580d79ca1de95fe6045350f7022 707 Gene3D G3DSA:3.40.50.740 323 536 9.0E-53 T 22-04-2016 HRM2_RS07085 a36b8580d79ca1de95fe6045350f7022 707 Pfam PF01568 Molydopterin dinucleotide binding domain 581 689 2.6E-21 T 22-04-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 HRM2_RS07085 a36b8580d79ca1de95fe6045350f7022 707 PANTHER PTHR11615 1 697 2.0E-100 T 22-04-2016 HRM2_RS06560 fc652b0a7cb5a65f6c8f22b26310d4df 746 SUPERFAMILY SSF55729 14 152 1.86E-10 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS06560 fc652b0a7cb5a65f6c8f22b26310d4df 746 PRINTS PR01270 Histone deacetylase superfamily signature 420 435 1.5E-13 T 22-04-2016 IPR000286 Histone deacetylase superfamily HRM2_RS06560 fc652b0a7cb5a65f6c8f22b26310d4df 746 PRINTS PR01270 Histone deacetylase superfamily signature 506 516 1.5E-13 T 22-04-2016 IPR000286 Histone deacetylase superfamily HRM2_RS06560 fc652b0a7cb5a65f6c8f22b26310d4df 746 PRINTS PR01270 Histone deacetylase superfamily signature 389 412 1.5E-13 T 22-04-2016 IPR000286 Histone deacetylase superfamily HRM2_RS06560 fc652b0a7cb5a65f6c8f22b26310d4df 746 SUPERFAMILY SSF52768 249 573 2.54E-84 T 22-04-2016 HRM2_RS06560 fc652b0a7cb5a65f6c8f22b26310d4df 746 Pfam PF00850 Histone deacetylase domain 265 564 2.2E-66 T 22-04-2016 IPR023801 Histone deacetylase domain HRM2_RS06560 fc652b0a7cb5a65f6c8f22b26310d4df 746 PANTHER PTHR10625 251 313 1.7E-68 T 22-04-2016 IPR000286 Histone deacetylase superfamily HRM2_RS06560 fc652b0a7cb5a65f6c8f22b26310d4df 746 PANTHER PTHR10625 333 577 1.7E-68 T 22-04-2016 IPR000286 Histone deacetylase superfamily HRM2_RS06560 fc652b0a7cb5a65f6c8f22b26310d4df 746 Pfam PF00583 Acetyltransferase (GNAT) family 647 725 2.4E-11 T 22-04-2016 IPR000182 GNAT domain GO:0008080 HRM2_RS06560 fc652b0a7cb5a65f6c8f22b26310d4df 746 SUPERFAMILY SSF55729 600 735 1.69E-18 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS06560 fc652b0a7cb5a65f6c8f22b26310d4df 746 PANTHER PTHR10625:SF121 251 313 1.7E-68 T 22-04-2016 HRM2_RS06560 fc652b0a7cb5a65f6c8f22b26310d4df 746 PANTHER PTHR10625:SF121 333 577 1.7E-68 T 22-04-2016 HRM2_RS06560 fc652b0a7cb5a65f6c8f22b26310d4df 746 Gene3D G3DSA:3.40.630.30 13 152 1.0E-10 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS06560 fc652b0a7cb5a65f6c8f22b26310d4df 746 Gene3D G3DSA:3.40.630.30 600 739 3.4E-25 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS06560 fc652b0a7cb5a65f6c8f22b26310d4df 746 Gene3D G3DSA:3.40.800.20 243 572 1.6E-75 T 22-04-2016 IPR023801 Histone deacetylase domain HRM2_RS05220 e41b90133f0d9168d99fa0f3ade1e044 125 Gene3D G3DSA:2.30.110.10 4 117 3.0E-16 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 HRM2_RS05220 e41b90133f0d9168d99fa0f3ade1e044 125 SUPERFAMILY SSF50475 5 116 5.89E-17 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 HRM2_RS05220 e41b90133f0d9168d99fa0f3ade1e044 125 PANTHER PTHR40660 1 119 2.7E-17 T 22-04-2016 HRM2_RS05220 e41b90133f0d9168d99fa0f3ade1e044 125 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 90 3.1E-8 T 22-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 HRM2_RS13550 64cad5e202596d829d0055e245b42b28 400 Gene3D G3DSA:3.30.70.1380 250 338 4.9E-31 T 22-04-2016 HRM2_RS13550 64cad5e202596d829d0055e245b42b28 400 PANTHER PTHR36566 1 391 3.8E-91 T 22-04-2016 HRM2_RS13550 64cad5e202596d829d0055e245b42b28 400 PANTHER PTHR36566:SF1 1 391 3.8E-91 T 22-04-2016 HRM2_RS13550 64cad5e202596d829d0055e245b42b28 400 TIGRFAM TIGR00299 TIGR00299: TIGR00299 family protein 2 388 1.4E-101 T 22-04-2016 IPR002822 Uncharacterised protein family UPF0272 HRM2_RS13550 64cad5e202596d829d0055e245b42b28 400 Gene3D G3DSA:3.10.20.300 340 390 5.4E-10 T 22-04-2016 HRM2_RS13550 64cad5e202596d829d0055e245b42b28 400 Hamap MF_01074 UPF0272 protein . 1 397 37.052 T 22-04-2016 IPR002822 Uncharacterised protein family UPF0272 HRM2_RS13550 64cad5e202596d829d0055e245b42b28 400 Pfam PF01969 Protein of unknown function DUF111 4 388 6.7E-132 T 22-04-2016 IPR002822 Uncharacterised protein family UPF0272 HRM2_RS16730 783f5f331fd6d49b52f00acd33b2e89b 217 PANTHER PTHR12962 104 189 2.1E-30 T 22-04-2016 HRM2_RS16730 783f5f331fd6d49b52f00acd33b2e89b 217 SMART SM00357 4 68 1.3E-4 T 22-04-2016 IPR011129 Cold shock protein GO:0003676 HRM2_RS16730 783f5f331fd6d49b52f00acd33b2e89b 217 PANTHER PTHR12962:SF1 104 189 2.1E-30 T 22-04-2016 HRM2_RS16730 783f5f331fd6d49b52f00acd33b2e89b 217 Pfam PF06961 Protein of unknown function (DUF1294) 116 170 3.2E-25 T 22-04-2016 IPR010718 Protein of unknown function DUF1294 HRM2_RS16730 783f5f331fd6d49b52f00acd33b2e89b 217 Pfam PF00313 'Cold-shock' DNA-binding domain 4 66 7.8E-10 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HRM2_RS16730 783f5f331fd6d49b52f00acd33b2e89b 217 SUPERFAMILY SSF50249 2 70 8.08E-14 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS16730 783f5f331fd6d49b52f00acd33b2e89b 217 Gene3D G3DSA:2.40.50.140 3 70 6.7E-18 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS02690 0e410533129ba5adb65e4d0d77c78431 332 Gene3D G3DSA:1.10.10.10 4 67 4.6E-5 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS02690 0e410533129ba5adb65e4d0d77c78431 332 PANTHER PTHR34580:SF1 1 330 1.4E-38 T 22-04-2016 HRM2_RS02690 0e410533129ba5adb65e4d0d77c78431 332 PANTHER PTHR34580 1 330 1.4E-38 T 22-04-2016 HRM2_RS02690 0e410533129ba5adb65e4d0d77c78431 332 Pfam PF13280 WYL domain 154 326 1.9E-32 T 22-04-2016 IPR026881 WYL domain HRM2_RS02690 0e410533129ba5adb65e4d0d77c78431 332 SUPERFAMILY SSF46785 5 73 2.26E-5 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS24735 41c17278d662946d51a7feba4a0a867e 172 Pfam PF00873 AcrB/AcrD/AcrF family 3 171 2.1E-36 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS24735 41c17278d662946d51a7feba4a0a867e 172 SUPERFAMILY SSF82866 45 171 4.45E-25 T 22-04-2016 HRM2_RS24735 41c17278d662946d51a7feba4a0a867e 172 PANTHER PTHR32063:SF19 2 171 4.6E-81 T 22-04-2016 HRM2_RS24735 41c17278d662946d51a7feba4a0a867e 172 Gene3D G3DSA:1.10.3850.10 51 171 2.3E-26 T 22-04-2016 HRM2_RS24735 41c17278d662946d51a7feba4a0a867e 172 PANTHER PTHR32063 2 171 4.6E-81 T 22-04-2016 HRM2_RS24735 41c17278d662946d51a7feba4a0a867e 172 Gene3D G3DSA:3.30.2090.10 3 48 2.8E-5 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS24735 41c17278d662946d51a7feba4a0a867e 172 SUPERFAMILY SSF82714 3 44 3.92E-5 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS02980 c1e817b022b9b2d744db0f105ff5cee1 482 PANTHER PTHR21248 14 482 2.1E-125 T 22-04-2016 HRM2_RS02980 c1e817b022b9b2d744db0f105ff5cee1 482 Gene3D G3DSA:3.30.870.10 117 311 5.0E-48 T 22-04-2016 HRM2_RS02980 c1e817b022b9b2d744db0f105ff5cee1 482 PANTHER PTHR21248:SF10 14 482 2.1E-125 T 22-04-2016 HRM2_RS02980 c1e817b022b9b2d744db0f105ff5cee1 482 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 10 482 2.0E-136 T 22-04-2016 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 HRM2_RS02980 c1e817b022b9b2d744db0f105ff5cee1 482 Gene3D G3DSA:3.30.870.10 312 457 1.1E-31 T 22-04-2016 HRM2_RS02980 c1e817b022b9b2d744db0f105ff5cee1 482 SUPERFAMILY SSF56024 106 312 4.4E-51 T 22-04-2016 HRM2_RS02980 c1e817b022b9b2d744db0f105ff5cee1 482 SUPERFAMILY SSF56024 270 462 2.24E-45 T 22-04-2016 HRM2_RS02980 c1e817b022b9b2d744db0f105ff5cee1 482 SMART SM00155 395 422 8.3E-5 T 22-04-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 HRM2_RS02980 c1e817b022b9b2d744db0f105ff5cee1 482 SMART SM00155 218 245 7.2E-6 T 22-04-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 HRM2_RS02980 c1e817b022b9b2d744db0f105ff5cee1 482 Pfam PF13091 PLD-like domain 136 275 4.8E-13 T 22-04-2016 IPR025202 Phospholipase D-like domain HRM2_RS02980 c1e817b022b9b2d744db0f105ff5cee1 482 Pfam PF13091 PLD-like domain 325 449 5.2E-23 T 22-04-2016 IPR025202 Phospholipase D-like domain HRM2_RS02980 c1e817b022b9b2d744db0f105ff5cee1 482 Hamap MF_01916 Cardiolipin synthase. 9 482 38.57 T 22-04-2016 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 HRM2_RS02980 c1e817b022b9b2d744db0f105ff5cee1 482 Pfam PF13396 Phospholipase_D-nuclease N-terminal 17 56 7.4E-10 T 22-04-2016 IPR027379 Cardiolipin synthase N-terminal HRM2_RS21770 eb5ddb8ef55b0a1986648f6c0944856b 692 SMART SM00382 37 235 8.4E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS21770 eb5ddb8ef55b0a1986648f6c0944856b 692 SMART SM00382 387 587 2.8E-15 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS21770 eb5ddb8ef55b0a1986648f6c0944856b 692 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 323 1.2E-23 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HRM2_RS21770 eb5ddb8ef55b0a1986648f6c0944856b 692 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 579 666 1.2E-23 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HRM2_RS21770 eb5ddb8ef55b0a1986648f6c0944856b 692 PANTHER PTHR24220:SF535 10 293 1.2E-123 T 22-04-2016 HRM2_RS21770 eb5ddb8ef55b0a1986648f6c0944856b 692 PANTHER PTHR24220:SF535 378 489 1.2E-123 T 22-04-2016 HRM2_RS21770 eb5ddb8ef55b0a1986648f6c0944856b 692 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 304 2.6E-18 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HRM2_RS21770 eb5ddb8ef55b0a1986648f6c0944856b 692 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 581 645 6.1E-17 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HRM2_RS21770 eb5ddb8ef55b0a1986648f6c0944856b 692 Gene3D G3DSA:3.40.50.300 342 609 8.2E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21770 eb5ddb8ef55b0a1986648f6c0944856b 692 Gene3D G3DSA:3.40.50.300 4 266 9.0E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21770 eb5ddb8ef55b0a1986648f6c0944856b 692 SUPERFAMILY SSF52540 9 257 3.01E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21770 eb5ddb8ef55b0a1986648f6c0944856b 692 PANTHER PTHR24220 10 293 1.2E-123 T 22-04-2016 HRM2_RS21770 eb5ddb8ef55b0a1986648f6c0944856b 692 PANTHER PTHR24220 378 489 1.2E-123 T 22-04-2016 HRM2_RS21770 eb5ddb8ef55b0a1986648f6c0944856b 692 SUPERFAMILY SSF52540 351 600 7.86E-65 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21770 eb5ddb8ef55b0a1986648f6c0944856b 692 ProSitePatterns PS00211 ABC transporters family signature. 502 516 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS21770 eb5ddb8ef55b0a1986648f6c0944856b 692 Pfam PF00005 ABC transporter 379 529 1.2E-30 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS21770 eb5ddb8ef55b0a1986648f6c0944856b 692 Pfam PF00005 ABC transporter 29 186 9.0E-25 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS10715 b9b4ec62f161db3793b506050bf336da 810 SUPERFAMILY SSF53756 4 809 1.02E-302 T 22-04-2016 HRM2_RS10715 b9b4ec62f161db3793b506050bf336da 810 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 9 806 0.0 T 22-04-2016 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HRM2_RS10715 b9b4ec62f161db3793b506050bf336da 810 PANTHER PTHR11468:SF3 17 810 0.0 T 22-04-2016 HRM2_RS10715 b9b4ec62f161db3793b506050bf336da 810 PIRSF PIRSF000460 1 809 7.0E-217 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HRM2_RS10715 b9b4ec62f161db3793b506050bf336da 810 Pfam PF00343 Carbohydrate phosphorylase 94 806 0.0 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HRM2_RS10715 b9b4ec62f161db3793b506050bf336da 810 PANTHER PTHR11468 17 810 0.0 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HRM2_RS10715 b9b4ec62f161db3793b506050bf336da 810 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 651 663 - T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HRM2_RS10715 b9b4ec62f161db3793b506050bf336da 810 Gene3D G3DSA:3.40.50.2000 5 476 6.8E-191 T 22-04-2016 HRM2_RS10715 b9b4ec62f161db3793b506050bf336da 810 Gene3D G3DSA:3.40.50.2000 477 791 1.4E-127 T 22-04-2016 HRM2_RS10640 6124def69e45b77c03c83fd0e85b3018 349 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 56 319 4.4E-43 T 22-04-2016 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 HRM2_RS10640 6124def69e45b77c03c83fd0e85b3018 349 PANTHER PTHR33376:SF5 45 347 2.7E-57 T 22-04-2016 HRM2_RS10640 6124def69e45b77c03c83fd0e85b3018 349 PANTHER PTHR33376 45 347 2.7E-57 T 22-04-2016 HRM2_RS02585 dc3b4964a0d1fa6d189360ccec7f9daa 283 TIGRFAM TIGR00067 glut_race: glutamate racemase 24 268 1.3E-64 T 22-04-2016 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS02585 dc3b4964a0d1fa6d189360ccec7f9daa 283 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 87 95 - T 22-04-2016 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS02585 dc3b4964a0d1fa6d189360ccec7f9daa 283 Gene3D G3DSA:3.40.50.1860 20 189 3.5E-49 T 22-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS02585 dc3b4964a0d1fa6d189360ccec7f9daa 283 PANTHER PTHR21198 16 279 2.1E-86 T 22-04-2016 HRM2_RS02585 dc3b4964a0d1fa6d189360ccec7f9daa 283 PANTHER PTHR21198:SF2 16 279 2.1E-86 T 22-04-2016 HRM2_RS02585 dc3b4964a0d1fa6d189360ccec7f9daa 283 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 196 206 - T 22-04-2016 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS02585 dc3b4964a0d1fa6d189360ccec7f9daa 283 SUPERFAMILY SSF53681 22 123 2.35E-33 T 22-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS02585 dc3b4964a0d1fa6d189360ccec7f9daa 283 Pfam PF01177 Asp/Glu/Hydantoin racemase 23 231 1.5E-29 T 22-04-2016 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS02585 dc3b4964a0d1fa6d189360ccec7f9daa 283 SUPERFAMILY SSF53681 125 268 2.62E-33 T 22-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS02585 dc3b4964a0d1fa6d189360ccec7f9daa 283 Hamap MF_00258 Glutamate racemase [murI]. 21 272 34.569 T 22-04-2016 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS09315 0635168b7d14959d54e7d2f2e510cbc8 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 427 2.46E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS09315 0635168b7d14959d54e7d2f2e510cbc8 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 469 2.46E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS09315 0635168b7d14959d54e7d2f2e510cbc8 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 413 2.46E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS09315 0635168b7d14959d54e7d2f2e510cbc8 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 432 450 2.46E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS09315 0635168b7d14959d54e7d2f2e510cbc8 476 Pfam PF00512 His Kinase A (phospho-acceptor) domain 256 316 4.5E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS09315 0635168b7d14959d54e7d2f2e510cbc8 476 SUPERFAMILY SSF158472 204 246 2.75E-7 T 22-04-2016 HRM2_RS09315 0635168b7d14959d54e7d2f2e510cbc8 476 SUPERFAMILY SSF47384 233 317 1.02E-15 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS09315 0635168b7d14959d54e7d2f2e510cbc8 476 SMART SM00387 361 472 7.3E-33 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS09315 0635168b7d14959d54e7d2f2e510cbc8 476 Gene3D G3DSA:3.30.565.10 319 471 7.2E-44 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS09315 0635168b7d14959d54e7d2f2e510cbc8 476 Pfam PF00672 HAMP domain 177 244 2.2E-12 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS09315 0635168b7d14959d54e7d2f2e510cbc8 476 SUPERFAMILY SSF55874 305 470 2.36E-46 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS09315 0635168b7d14959d54e7d2f2e510cbc8 476 SMART SM00388 250 316 1.3E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS09315 0635168b7d14959d54e7d2f2e510cbc8 476 Gene3D G3DSA:1.10.287.130 240 312 8.3E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS09315 0635168b7d14959d54e7d2f2e510cbc8 476 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 364 471 1.3E-20 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS09315 0635168b7d14959d54e7d2f2e510cbc8 476 SMART SM00304 196 249 7.6E-9 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS09315 0635168b7d14959d54e7d2f2e510cbc8 476 PANTHER PTHR24423 190 471 5.5E-78 T 22-04-2016 HRM2_RS09315 0635168b7d14959d54e7d2f2e510cbc8 476 PANTHER PTHR24423 92 102 5.5E-78 T 22-04-2016 HRM2_RS08730 14bc1000ece29217ce301359c5f3ea19 453 SUPERFAMILY SSF56645 2 239 9.69E-65 T 22-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 HRM2_RS08730 14bc1000ece29217ce301359c5f3ea19 453 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 374 1.1E-49 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS08730 14bc1000ece29217ce301359c5f3ea19 453 Gene3D G3DSA:1.10.540.10 2 113 7.6E-26 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS08730 14bc1000ece29217ce301359c5f3ea19 453 Gene3D G3DSA:2.20.28.10 409 443 4.3E-12 T 22-04-2016 IPR004039 Rubredoxin-type fold HRM2_RS08730 14bc1000ece29217ce301359c5f3ea19 453 SUPERFAMILY SSF57802 411 443 1.85E-8 T 22-04-2016 HRM2_RS08730 14bc1000ece29217ce301359c5f3ea19 453 PANTHER PTHR10909 3 403 8.1E-137 T 22-04-2016 HRM2_RS08730 14bc1000ece29217ce301359c5f3ea19 453 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 115 5.5E-18 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS08730 14bc1000ece29217ce301359c5f3ea19 453 Gene3D G3DSA:2.40.110.10 122 218 5.2E-35 T 22-04-2016 HRM2_RS08730 14bc1000ece29217ce301359c5f3ea19 453 SUPERFAMILY SSF47203 227 383 1.41E-56 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS08730 14bc1000ece29217ce301359c5f3ea19 453 PANTHER PTHR10909:SF305 3 403 8.1E-137 T 22-04-2016 HRM2_RS08730 14bc1000ece29217ce301359c5f3ea19 453 Gene3D G3DSA:1.20.140.10 219 382 2.1E-66 T 22-04-2016 HRM2_RS08730 14bc1000ece29217ce301359c5f3ea19 453 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 2.5E-23 T 22-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 HRM2_RS04665 ce0257ec97d09fd59c27acf98948e964 562 Gene3D G3DSA:3.30.420.10 154 298 4.1E-5 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS03155 ce0257ec97d09fd59c27acf98948e964 562 Gene3D G3DSA:3.30.420.10 154 298 4.1E-5 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS00725 559f10bd1ee3227dd05b5d481ba70edd 348 SMART SM00876 225 318 0.0048 T 22-04-2016 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 HRM2_RS00725 559f10bd1ee3227dd05b5d481ba70edd 348 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 229 308 7.1E-7 T 22-04-2016 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 HRM2_RS00725 559f10bd1ee3227dd05b5d481ba70edd 348 Pfam PF04055 Radical SAM superfamily 55 208 9.4E-19 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS00725 559f10bd1ee3227dd05b5d481ba70edd 348 TIGRFAM TIGR03956 rSAM_HydE: [FeFe] hydrogenase H-cluster radical SAM maturase HydE 22 339 5.0E-101 T 22-04-2016 IPR024021 [FeFe]-hydrogenase maturation HydE, radical SAM HRM2_RS00725 559f10bd1ee3227dd05b5d481ba70edd 348 PIRSF PIRSF004762 5 325 2.4E-59 T 22-04-2016 IPR005244 FO synthase, subunit 2-like GO:0016765|GO:0051188|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198|UniPathway: UPA00072 HRM2_RS00725 559f10bd1ee3227dd05b5d481ba70edd 348 Gene3D G3DSA:3.20.20.70 16 302 3.9E-72 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS00725 559f10bd1ee3227dd05b5d481ba70edd 348 PANTHER PTHR22976:SF28 30 348 1.1E-87 T 22-04-2016 HRM2_RS00725 559f10bd1ee3227dd05b5d481ba70edd 348 SUPERFAMILY SSF102114 15 290 1.83E-54 T 22-04-2016 HRM2_RS00725 559f10bd1ee3227dd05b5d481ba70edd 348 SMART SM00729 49 257 5.5E-24 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS00725 559f10bd1ee3227dd05b5d481ba70edd 348 PANTHER PTHR22976 30 348 1.1E-87 T 22-04-2016 HRM2_RS19410 0fc2b4a58749a92dc820c1ea0ade32fe 433 PANTHER PTHR35093:SF2 9 433 9.8E-82 T 22-04-2016 HRM2_RS19410 0fc2b4a58749a92dc820c1ea0ade32fe 433 PANTHER PTHR35093 9 433 9.8E-82 T 22-04-2016 HRM2_RS19410 0fc2b4a58749a92dc820c1ea0ade32fe 433 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 19 433 3.2E-72 T 22-04-2016 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) HRM2_RS19410 0fc2b4a58749a92dc820c1ea0ade32fe 433 Gene3D G3DSA:2.40.160.60 28 433 1.2E-106 T 22-04-2016 HRM2_RS19410 0fc2b4a58749a92dc820c1ea0ade32fe 433 SUPERFAMILY SSF56935 28 433 5.86E-78 T 22-04-2016 HRM2_RS23810 c93f291c38330e0eaca591f8a4bc6341 667 SUPERFAMILY SSF52518 6 328 2.27E-114 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS23810 c93f291c38330e0eaca591f8a4bc6341 667 PANTHER PTHR11624 5 315 0.0 T 22-04-2016 IPR033247 Transketolase family HRM2_RS23810 c93f291c38330e0eaca591f8a4bc6341 667 PANTHER PTHR11624 344 667 0.0 T 22-04-2016 IPR033247 Transketolase family HRM2_RS23810 c93f291c38330e0eaca591f8a4bc6341 667 Gene3D G3DSA:3.40.50.970 5 328 2.3E-123 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS23810 c93f291c38330e0eaca591f8a4bc6341 667 Gene3D G3DSA:3.40.50.970 340 533 8.3E-77 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS23810 c93f291c38330e0eaca591f8a4bc6341 667 Pfam PF02779 Transketolase, pyrimidine binding domain 357 528 1.7E-47 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain HRM2_RS23810 c93f291c38330e0eaca591f8a4bc6341 667 SUPERFAMILY SSF52922 538 666 8.51E-41 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HRM2_RS23810 c93f291c38330e0eaca591f8a4bc6341 667 PANTHER PTHR11624:SF1 5 315 0.0 T 22-04-2016 HRM2_RS23810 c93f291c38330e0eaca591f8a4bc6341 667 PANTHER PTHR11624:SF1 344 667 0.0 T 22-04-2016 HRM2_RS23810 c93f291c38330e0eaca591f8a4bc6341 667 SUPERFAMILY SSF52518 345 530 6.05E-71 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS23810 c93f291c38330e0eaca591f8a4bc6341 667 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 9 338 2.9E-147 T 22-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 HRM2_RS23810 c93f291c38330e0eaca591f8a4bc6341 667 ProSitePatterns PS00802 Transketolase signature 2. 471 487 - T 22-04-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 HRM2_RS23810 c93f291c38330e0eaca591f8a4bc6341 667 ProSitePatterns PS00801 Transketolase signature 1. 17 37 - T 22-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 HRM2_RS23810 c93f291c38330e0eaca591f8a4bc6341 667 Pfam PF02780 Transketolase, C-terminal domain 548 657 1.3E-13 T 22-04-2016 IPR033248 Transketolase, C-terminal domain HRM2_RS23810 c93f291c38330e0eaca591f8a4bc6341 667 TIGRFAM TIGR00232 tktlase_bact: transketolase 11 666 7.5E-279 T 22-04-2016 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 HRM2_RS23810 c93f291c38330e0eaca591f8a4bc6341 667 SMART SM00861 358 529 6.2E-70 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain HRM2_RS23810 c93f291c38330e0eaca591f8a4bc6341 667 Gene3D G3DSA:3.40.50.920 541 666 1.8E-50 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HRM2_RS10010 4519bc2d763c107f45b47990966df8bb 418 PANTHER PTHR30489 9 418 1.1E-50 T 22-04-2016 HRM2_RS10010 4519bc2d763c107f45b47990966df8bb 418 Pfam PF02687 FtsX-like permease family 288 408 2.4E-17 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 HRM2_RS10010 4519bc2d763c107f45b47990966df8bb 418 Pfam PF12704 MacB-like periplasmic core domain 21 249 2.1E-14 T 22-04-2016 IPR025857 MacB-like periplasmic core domain HRM2_RS00295 99bafbecc41c5dc9eddd08d367cea57f 362 Pfam PF03595 Voltage-dependent anion channel 21 342 2.0E-49 T 22-04-2016 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 HRM2_RS00295 99bafbecc41c5dc9eddd08d367cea57f 362 PANTHER PTHR31686 3 346 2.5E-15 T 22-04-2016 HRM2_RS15470 d0ddc1a7b41f7765f40a1bbe85668b74 61 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 19.307 T 22-04-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 HRM2_RS15470 d0ddc1a7b41f7765f40a1bbe85668b74 61 Pfam PF01783 Ribosomal L32p protein family 2 54 9.8E-22 T 22-04-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 HRM2_RS15470 d0ddc1a7b41f7765f40a1bbe85668b74 61 SUPERFAMILY SSF57829 1 54 1.04E-19 T 22-04-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 HRM2_RS15470 d0ddc1a7b41f7765f40a1bbe85668b74 61 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 54 3.6E-22 T 22-04-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 HRM2_RS15470 d0ddc1a7b41f7765f40a1bbe85668b74 61 PANTHER PTHR21026 1 54 2.6E-14 T 22-04-2016 HRM2_RS07025 b302ecc0df3a20907bd793082a0c4a59 266 Gene3D G3DSA:1.10.3720.10 7 265 1.7E-58 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS07025 b302ecc0df3a20907bd793082a0c4a59 266 PANTHER PTHR30222 18 261 1.8E-58 T 22-04-2016 HRM2_RS07025 b302ecc0df3a20907bd793082a0c4a59 266 SUPERFAMILY SSF161098 4 260 1.96E-51 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS07025 b302ecc0df3a20907bd793082a0c4a59 266 PANTHER PTHR30222:SF6 18 261 1.8E-58 T 22-04-2016 HRM2_RS07025 b302ecc0df3a20907bd793082a0c4a59 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 259 5.4E-15 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS06410 7c6be0ede585d9f89bbc3f0b0e7b70ea 309 PANTHER PTHR30465 25 309 1.0E-92 T 22-04-2016 HRM2_RS06410 7c6be0ede585d9f89bbc3f0b0e7b70ea 309 SUPERFAMILY SSF161098 103 290 2.49E-20 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS06410 7c6be0ede585d9f89bbc3f0b0e7b70ea 309 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 26 78 1.4E-7 T 22-04-2016 IPR025966 Oligopeptide transport permease C-like, N-terminal domain HRM2_RS06410 7c6be0ede585d9f89bbc3f0b0e7b70ea 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 304 2.5E-20 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS06410 7c6be0ede585d9f89bbc3f0b0e7b70ea 309 Gene3D G3DSA:1.10.3720.10 102 301 1.4E-18 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS06410 7c6be0ede585d9f89bbc3f0b0e7b70ea 309 PANTHER PTHR30465:SF2 25 309 1.0E-92 T 22-04-2016 HRM2_RS00905 39e6ad437778582cf62785d7c3fbb028 498 PANTHER PTHR11596 415 496 8.0E-100 T 22-04-2016 HRM2_RS00905 39e6ad437778582cf62785d7c3fbb028 498 PANTHER PTHR11596 40 369 8.0E-100 T 22-04-2016 HRM2_RS00905 39e6ad437778582cf62785d7c3fbb028 498 Gene3D G3DSA:3.40.720.10 431 494 1.5E-114 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 HRM2_RS00905 39e6ad437778582cf62785d7c3fbb028 498 Gene3D G3DSA:3.40.720.10 31 371 1.5E-114 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 HRM2_RS00905 39e6ad437778582cf62785d7c3fbb028 498 Pfam PF00245 Alkaline phosphatase 42 486 7.0E-66 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 HRM2_RS00905 39e6ad437778582cf62785d7c3fbb028 498 PANTHER PTHR11596:SF5 415 496 8.0E-100 T 22-04-2016 HRM2_RS00905 39e6ad437778582cf62785d7c3fbb028 498 PANTHER PTHR11596:SF5 40 369 8.0E-100 T 22-04-2016 HRM2_RS00905 39e6ad437778582cf62785d7c3fbb028 498 SMART SM00098 43 490 1.1E-28 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 HRM2_RS00905 39e6ad437778582cf62785d7c3fbb028 498 PRINTS PR00113 Alkaline phosphatase signature 170 180 4.6E-20 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 HRM2_RS00905 39e6ad437778582cf62785d7c3fbb028 498 PRINTS PR00113 Alkaline phosphatase signature 246 275 4.6E-20 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 HRM2_RS00905 39e6ad437778582cf62785d7c3fbb028 498 PRINTS PR00113 Alkaline phosphatase signature 42 62 4.6E-20 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 HRM2_RS00905 39e6ad437778582cf62785d7c3fbb028 498 PRINTS PR00113 Alkaline phosphatase signature 126 146 4.6E-20 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 HRM2_RS00905 39e6ad437778582cf62785d7c3fbb028 498 SUPERFAMILY SSF53649 22 371 2.36E-106 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 HRM2_RS00905 39e6ad437778582cf62785d7c3fbb028 498 SUPERFAMILY SSF53649 431 491 2.36E-106 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 HRM2_RS19315 5e99c890334cec0262d69807484b40a5 92 Gene3D G3DSA:3.40.50.720 1 39 6.9E-12 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS19315 5e99c890334cec0262d69807484b40a5 92 Gene3D G3DSA:3.40.50.720 74 79 6.9E-12 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS19315 5e99c890334cec0262d69807484b40a5 92 Pfam PF01494 FAD binding domain 8 40 2.8E-5 T 22-04-2016 IPR002938 FAD-binding domain GO:0071949 HRM2_RS19315 5e99c890334cec0262d69807484b40a5 92 SUPERFAMILY SSF51905 1 39 8.63E-10 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS19230 49014e457b84f2612a5df0af794609ec 215 PANTHER PTHR38601:SF1 1 215 6.4E-36 T 22-04-2016 HRM2_RS19230 49014e457b84f2612a5df0af794609ec 215 PANTHER PTHR38601 1 215 6.4E-36 T 22-04-2016 HRM2_RS19230 49014e457b84f2612a5df0af794609ec 215 ProDom PD037531 MEMBRANE HYDROGENASE SUBUNIT COMPONENT HYDROGENASE-4 E OXIDOREDUCTASE PRECURSOR SIGNAL 1.-.-.- 28 190 1.0E-22 T 22-04-2016 HRM2_RS13770 342ed6f99fd1be04ad57e2fa678fff61 276 Gene3D G3DSA:3.20.20.70 14 270 2.0E-109 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS13770 342ed6f99fd1be04ad57e2fa678fff61 276 Pfam PF00793 DAHP synthetase I family 13 260 9.5E-65 T 22-04-2016 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 HRM2_RS13770 342ed6f99fd1be04ad57e2fa678fff61 276 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 15 269 3.0E-114 T 22-04-2016 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 HRM2_RS13770 342ed6f99fd1be04ad57e2fa678fff61 276 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 10 272 49.702 T 22-04-2016 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 HRM2_RS13770 342ed6f99fd1be04ad57e2fa678fff61 276 PANTHER PTHR21057 16 269 1.7E-143 T 22-04-2016 HRM2_RS13770 342ed6f99fd1be04ad57e2fa678fff61 276 PANTHER PTHR21057:SF2 16 269 1.7E-143 T 22-04-2016 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 HRM2_RS13770 342ed6f99fd1be04ad57e2fa678fff61 276 SUPERFAMILY SSF51569 11 270 2.29E-97 T 22-04-2016 HRM2_RS25300 9110d3ba43de8d573fe4f37dc9ef01e0 231 Pfam PF13174 Tetratricopeptide repeat 185 215 0.11 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS25300 9110d3ba43de8d573fe4f37dc9ef01e0 231 PANTHER PTHR26312:SF74 124 228 6.1E-17 T 22-04-2016 HRM2_RS25300 9110d3ba43de8d573fe4f37dc9ef01e0 231 Gene3D G3DSA:1.25.40.10 112 212 4.0E-15 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS25300 9110d3ba43de8d573fe4f37dc9ef01e0 231 PANTHER PTHR26312 124 228 6.1E-17 T 22-04-2016 HRM2_RS25300 9110d3ba43de8d573fe4f37dc9ef01e0 231 Pfam PF13432 Tetratricopeptide repeat 114 178 2.2E-10 T 22-04-2016 HRM2_RS25300 9110d3ba43de8d573fe4f37dc9ef01e0 231 SUPERFAMILY SSF48452 109 215 4.3E-16 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS25300 9110d3ba43de8d573fe4f37dc9ef01e0 231 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 113 227 1.0E-31 T 22-04-2016 IPR014162 Tol-Pal system, YbgF HRM2_RS07510 f358ea02f752ac17d9876397dcfdc722 84 Pfam PF03597 Cytochrome oxidase maturation protein cbb3-type 15 36 2.4E-6 T 22-04-2016 IPR004714 Cytochrome oxidase maturation protein cbb3-type HRM2_RS02005 383be1c6752748c4d1bc8c465b3c3c26 200 Pfam PF13835 Domain of unknown function (DUF4194) 14 175 2.1E-44 T 22-04-2016 IPR025449 Protein of unknown function DUF4194 HRM2_RS21640 24e3aa867ee27ea2c2ce92049b4c139e 369 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 12 350 1.7E-13 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase HRM2_RS21640 24e3aa867ee27ea2c2ce92049b4c139e 369 Gene3D G3DSA:3.60.10.10 216 353 3.4E-10 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase HRM2_RS21640 24e3aa867ee27ea2c2ce92049b4c139e 369 Gene3D G3DSA:3.60.10.10 10 183 3.4E-10 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase HRM2_RS21640 24e3aa867ee27ea2c2ce92049b4c139e 369 SUPERFAMILY SSF56219 9 111 5.88E-20 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase HRM2_RS21640 24e3aa867ee27ea2c2ce92049b4c139e 369 SUPERFAMILY SSF56219 143 184 5.88E-20 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase HRM2_RS21640 24e3aa867ee27ea2c2ce92049b4c139e 369 SUPERFAMILY SSF56219 211 358 5.88E-20 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase HRM2_RS06255 8116aaa38c196801fec5fd2b66b367b6 325 Pfam PF07670 Nucleoside recognition 192 278 6.8E-6 T 22-04-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 HRM2_RS06255 8116aaa38c196801fec5fd2b66b367b6 325 PANTHER PTHR38139:SF1 3 325 2.0E-50 T 22-04-2016 HRM2_RS06255 8116aaa38c196801fec5fd2b66b367b6 325 PANTHER PTHR38139 3 325 2.0E-50 T 22-04-2016 HRM2_RS09580 8532fb2e2feb67c83b43250f4c7da6bf 281 PANTHER PTHR35894 6 266 1.2E-29 T 22-04-2016 HRM2_RS09580 8532fb2e2feb67c83b43250f4c7da6bf 281 SMART SM00382 45 200 9.5E-5 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS09580 8532fb2e2feb67c83b43250f4c7da6bf 281 Gene3D G3DSA:3.40.50.300 34 194 1.5E-11 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09580 8532fb2e2feb67c83b43250f4c7da6bf 281 Pfam PF13401 AAA domain 45 176 6.6E-16 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS09580 8532fb2e2feb67c83b43250f4c7da6bf 281 SUPERFAMILY SSF52540 46 266 5.85E-19 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22020 8532fb2e2feb67c83b43250f4c7da6bf 281 PANTHER PTHR35894 6 266 1.2E-29 T 22-04-2016 HRM2_RS22020 8532fb2e2feb67c83b43250f4c7da6bf 281 SMART SM00382 45 200 9.5E-5 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS22020 8532fb2e2feb67c83b43250f4c7da6bf 281 Gene3D G3DSA:3.40.50.300 34 194 1.5E-11 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22020 8532fb2e2feb67c83b43250f4c7da6bf 281 Pfam PF13401 AAA domain 45 176 6.6E-16 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS22020 8532fb2e2feb67c83b43250f4c7da6bf 281 SUPERFAMILY SSF52540 46 266 5.85E-19 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22685 d6a8598bfd501f0ca46ec41d5b38b565 435 SUPERFAMILY SSF81301 4 126 8.61E-25 T 22-04-2016 HRM2_RS22685 d6a8598bfd501f0ca46ec41d5b38b565 435 Pfam PF01743 Poly A polymerase head domain 23 128 3.8E-18 T 22-04-2016 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 HRM2_RS22685 d6a8598bfd501f0ca46ec41d5b38b565 435 Gene3D G3DSA:3.30.460.10 5 128 5.1E-29 T 22-04-2016 HRM2_RS22685 d6a8598bfd501f0ca46ec41d5b38b565 435 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 283 428 1.1E-7 T 22-04-2016 IPR032810 CCA-adding enzyme, C-terminal HRM2_RS22685 d6a8598bfd501f0ca46ec41d5b38b565 435 PANTHER PTHR13734 11 322 1.4E-53 T 22-04-2016 HRM2_RS22685 d6a8598bfd501f0ca46ec41d5b38b565 435 PANTHER PTHR13734 339 427 1.4E-53 T 22-04-2016 HRM2_RS22685 d6a8598bfd501f0ca46ec41d5b38b565 435 SUPERFAMILY SSF81891 127 430 6.28E-43 T 22-04-2016 HRM2_RS22685 d6a8598bfd501f0ca46ec41d5b38b565 435 Gene3D G3DSA:1.10.3090.10 129 309 9.9E-35 T 22-04-2016 HRM2_RS22685 d6a8598bfd501f0ca46ec41d5b38b565 435 Gene3D G3DSA:1.10.3090.10 379 401 9.9E-35 T 22-04-2016 HRM2_RS22685 d6a8598bfd501f0ca46ec41d5b38b565 435 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 158 217 1.7E-9 T 22-04-2016 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain HRM2_RS21570 a8c1b21a64ffe7d3c6546ae828d1dc85 155 Gene3D G3DSA:3.30.429.20 1 52 1.2E-12 T 22-04-2016 HRM2_RS21570 a8c1b21a64ffe7d3c6546ae828d1dc85 155 Pfam PF01361 Tautomerase enzyme 2 52 7.4E-11 T 22-04-2016 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 HRM2_RS21570 a8c1b21a64ffe7d3c6546ae828d1dc85 155 SUPERFAMILY SSF55331 2 74 1.83E-11 T 22-04-2016 IPR014347 Tautomerase/MIF superfamily HRM2_RS17755 bf4c9981caa602948aa0fb46fdb7ea6d 307 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 230 246 - T 22-04-2016 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 HRM2_RS17755 bf4c9981caa602948aa0fb46fdb7ea6d 307 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 5 211 2.3E-78 T 22-04-2016 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 HRM2_RS17755 bf4c9981caa602948aa0fb46fdb7ea6d 307 PANTHER PTHR11557 1 303 2.0E-147 T 22-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 HRM2_RS17755 bf4c9981caa602948aa0fb46fdb7ea6d 307 SUPERFAMILY SSF53850 3 217 8.14E-82 T 22-04-2016 HRM2_RS17755 bf4c9981caa602948aa0fb46fdb7ea6d 307 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 4 296 38.348 T 22-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 HRM2_RS17755 bf4c9981caa602948aa0fb46fdb7ea6d 307 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 5 296 3.9E-112 T 22-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 HRM2_RS17755 bf4c9981caa602948aa0fb46fdb7ea6d 307 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 227 294 5.6E-15 T 22-04-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 HRM2_RS17755 bf4c9981caa602948aa0fb46fdb7ea6d 307 Gene3D G3DSA:3.30.160.40 221 304 1.3E-24 T 22-04-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 HRM2_RS17755 bf4c9981caa602948aa0fb46fdb7ea6d 307 SUPERFAMILY SSF54782 219 305 1.96E-23 T 22-04-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 HRM2_RS17755 bf4c9981caa602948aa0fb46fdb7ea6d 307 Gene3D G3DSA:3.40.190.10 2 109 3.3E-48 T 22-04-2016 HRM2_RS17755 bf4c9981caa602948aa0fb46fdb7ea6d 307 PIRSF PIRSF001438 1 307 5.4E-120 T 22-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 HRM2_RS17755 bf4c9981caa602948aa0fb46fdb7ea6d 307 PRINTS PR00151 Porphobilinogen deaminase signature 142 159 1.8E-44 T 22-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 HRM2_RS17755 bf4c9981caa602948aa0fb46fdb7ea6d 307 PRINTS PR00151 Porphobilinogen deaminase signature 75 94 1.8E-44 T 22-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 HRM2_RS17755 bf4c9981caa602948aa0fb46fdb7ea6d 307 PRINTS PR00151 Porphobilinogen deaminase signature 44 64 1.8E-44 T 22-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 HRM2_RS17755 bf4c9981caa602948aa0fb46fdb7ea6d 307 PRINTS PR00151 Porphobilinogen deaminase signature 123 140 1.8E-44 T 22-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 HRM2_RS17755 bf4c9981caa602948aa0fb46fdb7ea6d 307 PRINTS PR00151 Porphobilinogen deaminase signature 229 246 1.8E-44 T 22-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 HRM2_RS17755 bf4c9981caa602948aa0fb46fdb7ea6d 307 Gene3D G3DSA:3.40.190.10 110 198 6.6E-38 T 22-04-2016 HRM2_RS22990 8a9172e4fe4664e09897781ee20b3d8e 388 PANTHER PTHR32268 29 381 8.6E-176 T 22-04-2016 HRM2_RS22990 8a9172e4fe4664e09897781ee20b3d8e 388 Pfam PF00561 alpha/beta hydrolase fold 58 367 1.0E-35 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HRM2_RS22990 8a9172e4fe4664e09897781ee20b3d8e 388 PIRSF PIRSF000443 2 386 1.8E-143 T 22-04-2016 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344|UniPathway: UPA00051 HRM2_RS22990 8a9172e4fe4664e09897781ee20b3d8e 388 Gene3D G3DSA:3.40.50.1820 247 367 7.4E-36 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS22990 8a9172e4fe4664e09897781ee20b3d8e 388 Gene3D G3DSA:3.40.50.1820 40 215 7.4E-36 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS22990 8a9172e4fe4664e09897781ee20b3d8e 388 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 29 381 6.3E-143 T 22-04-2016 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344|UniPathway: UPA00051 HRM2_RS22990 8a9172e4fe4664e09897781ee20b3d8e 388 PANTHER PTHR32268:SF11 29 381 8.6E-176 T 22-04-2016 HRM2_RS22990 8a9172e4fe4664e09897781ee20b3d8e 388 Hamap MF_00296 Homoserine O-acetyltransferase [metX]. 12 383 47.946 T 22-04-2016 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344|UniPathway: UPA00051 HRM2_RS22990 8a9172e4fe4664e09897781ee20b3d8e 388 SUPERFAMILY SSF53474 29 382 1.84E-103 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS06090 9fb2f7c8da61aee8409c783699d47ed1 353 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 5 351 33.728 T 22-04-2016 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3|UniPathway: UPA00056 HRM2_RS06090 9fb2f7c8da61aee8409c783699d47ed1 353 SUPERFAMILY SSF51717 15 208 8.63E-10 T 22-04-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 HRM2_RS06090 9fb2f7c8da61aee8409c783699d47ed1 353 PIRSF PIRSF004640 2 353 4.4E-144 T 22-04-2016 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3|UniPathway: UPA00056 HRM2_RS06090 9fb2f7c8da61aee8409c783699d47ed1 353 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 7 349 4.5E-130 T 22-04-2016 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3|UniPathway: UPA00056 HRM2_RS06090 9fb2f7c8da61aee8409c783699d47ed1 353 PANTHER PTHR30454 7 352 2.7E-181 T 22-04-2016 HRM2_RS06090 9fb2f7c8da61aee8409c783699d47ed1 353 SUPERFAMILY SSF56014 264 349 2.24E-11 T 22-04-2016 HRM2_RS06090 9fb2f7c8da61aee8409c783699d47ed1 353 Gene3D G3DSA:3.20.20.120 66 138 5.7E-5 T 22-04-2016 IPR029065 Enolase C-terminal domain-like HRM2_RS06090 9fb2f7c8da61aee8409c783699d47ed1 353 Pfam PF04551 GcpE protein 10 350 3.8E-137 T 22-04-2016 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3|UniPathway: UPA00056 HRM2_RS16145 004c94104316f43c0dee09a7a88b076d 457 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 172 185 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS16145 004c94104316f43c0dee09a7a88b076d 457 Gene3D G3DSA:1.10.8.60 321 397 5.5E-22 T 22-04-2016 HRM2_RS16145 004c94104316f43c0dee09a7a88b076d 457 SUPERFAMILY SSF46689 362 457 5.02E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS16145 004c94104316f43c0dee09a7a88b076d 457 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 438 457 7.7E-11 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS16145 004c94104316f43c0dee09a7a88b076d 457 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 421 438 7.7E-11 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS16145 004c94104316f43c0dee09a7a88b076d 457 SUPERFAMILY SSF52540 147 391 1.29E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16145 004c94104316f43c0dee09a7a88b076d 457 Gene3D G3DSA:3.30.450.20 10 123 1.1E-19 T 22-04-2016 HRM2_RS16145 004c94104316f43c0dee09a7a88b076d 457 SUPERFAMILY SSF55785 5 123 4.71E-19 T 22-04-2016 IPR000014 PAS domain HRM2_RS16145 004c94104316f43c0dee09a7a88b076d 457 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 8 128 1.0E-14 T 22-04-2016 IPR000014 PAS domain HRM2_RS16145 004c94104316f43c0dee09a7a88b076d 457 Pfam PF00158 Sigma-54 interaction domain 148 314 1.4E-67 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS16145 004c94104316f43c0dee09a7a88b076d 457 Gene3D G3DSA:1.10.10.60 405 457 2.4E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS16145 004c94104316f43c0dee09a7a88b076d 457 SMART SM00382 168 311 5.0E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS16145 004c94104316f43c0dee09a7a88b076d 457 Gene3D G3DSA:3.40.50.300 144 320 1.1E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16145 004c94104316f43c0dee09a7a88b076d 457 PANTHER PTHR32071 122 457 8.8E-143 T 22-04-2016 HRM2_RS16145 004c94104316f43c0dee09a7a88b076d 457 Pfam PF02954 Bacterial regulatory protein, Fis family 420 455 6.8E-10 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS16145 004c94104316f43c0dee09a7a88b076d 457 Pfam PF13426 PAS domain 19 123 4.4E-14 T 22-04-2016 IPR000014 PAS domain HRM2_RS16145 004c94104316f43c0dee09a7a88b076d 457 SMART SM00091 8 76 2.1E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS12495 8ad97e81216e38a09722132b8023798d 402 Gene3D G3DSA:2.160.10.10 22 224 1.2E-9 T 22-04-2016 HRM2_RS12495 8ad97e81216e38a09722132b8023798d 402 SUPERFAMILY SSF51161 22 121 5.04E-7 T 22-04-2016 IPR011004 Trimeric LpxA-like HRM2_RS12495 8ad97e81216e38a09722132b8023798d 402 SUPERFAMILY SSF51161 180 217 5.04E-7 T 22-04-2016 IPR011004 Trimeric LpxA-like HRM2_RS15925 634fc7b6cc030843d11fd32fb7f5fb51 440 PANTHER PTHR30576 62 440 2.1E-111 T 22-04-2016 HRM2_RS15925 634fc7b6cc030843d11fd32fb7f5fb51 440 TIGRFAM TIGR03013 EpsB_2: sugar transferase, PEP-CTERM system associated 39 440 4.1E-141 T 22-04-2016 IPR017464 Sugar transferase, PEP-CTERM system associated HRM2_RS15925 634fc7b6cc030843d11fd32fb7f5fb51 440 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 31 438 3.0E-120 T 22-04-2016 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase HRM2_RS15925 634fc7b6cc030843d11fd32fb7f5fb51 440 PANTHER PTHR30576:SF0 62 440 2.1E-111 T 22-04-2016 HRM2_RS15925 634fc7b6cc030843d11fd32fb7f5fb51 440 Pfam PF02397 Bacterial sugar transferase 251 434 2.6E-58 T 22-04-2016 IPR003362 Bacterial sugar transferase HRM2_RS22250 d678290f8b0cb8787e56cae1ef8319b6 375 PANTHER PTHR24960 272 329 2.0E-13 T 22-04-2016 HRM2_RS22250 d678290f8b0cb8787e56cae1ef8319b6 375 PANTHER PTHR24960:SF20 272 329 2.0E-13 T 22-04-2016 HRM2_RS22250 d678290f8b0cb8787e56cae1ef8319b6 375 Pfam PF12838 4Fe-4S dicluster domain 276 319 1.1E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS22250 d678290f8b0cb8787e56cae1ef8319b6 375 Gene3D G3DSA:3.30.70.20 182 191 5.9E-18 T 22-04-2016 HRM2_RS22250 d678290f8b0cb8787e56cae1ef8319b6 375 Gene3D G3DSA:3.30.70.20 240 332 5.9E-18 T 22-04-2016 HRM2_RS22250 d678290f8b0cb8787e56cae1ef8319b6 375 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 305 316 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS22250 d678290f8b0cb8787e56cae1ef8319b6 375 SUPERFAMILY SSF54862 268 337 4.04E-22 T 22-04-2016 HRM2_RS22250 d678290f8b0cb8787e56cae1ef8319b6 375 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 276 287 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS00705 8b53875c1d5d1c05a4f0e6d0fdb1ab23 283 SUPERFAMILY SSF54001 86 276 4.35E-39 T 22-04-2016 HRM2_RS00705 8b53875c1d5d1c05a4f0e6d0fdb1ab23 283 PANTHER PTHR33490:SF1 3 269 2.0E-57 T 22-04-2016 HRM2_RS00705 8b53875c1d5d1c05a4f0e6d0fdb1ab23 283 Pfam PF01841 Transglutaminase-like superfamily 145 237 7.2E-21 T 22-04-2016 IPR002931 Transglutaminase-like HRM2_RS00705 8b53875c1d5d1c05a4f0e6d0fdb1ab23 283 SMART SM00460 174 239 4.0E-22 T 22-04-2016 IPR002931 Transglutaminase-like HRM2_RS00705 8b53875c1d5d1c05a4f0e6d0fdb1ab23 283 Gene3D G3DSA:3.90.260.10 178 241 3.6E-12 T 22-04-2016 IPR002931 Transglutaminase-like HRM2_RS00705 8b53875c1d5d1c05a4f0e6d0fdb1ab23 283 PANTHER PTHR33490 3 269 2.0E-57 T 22-04-2016 HRM2_RS00705 8b53875c1d5d1c05a4f0e6d0fdb1ab23 283 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 4 81 1.0E-20 T 22-04-2016 IPR013589 Bacterial transglutaminase-like, N-terminal HRM2_RS04950 c7b4b19db0c86edcc97b4526a67e1b8a 391 PANTHER PTHR18919 1 391 2.6E-191 T 22-04-2016 HRM2_RS04950 c7b4b19db0c86edcc97b4526a67e1b8a 391 Gene3D G3DSA:3.40.47.10 4 123 4.8E-73 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS04950 c7b4b19db0c86edcc97b4526a67e1b8a 391 Gene3D G3DSA:3.40.47.10 194 275 4.8E-73 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS04950 c7b4b19db0c86edcc97b4526a67e1b8a 391 Pfam PF02803 Thiolase, C-terminal domain 270 390 4.6E-44 T 22-04-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 HRM2_RS04950 c7b4b19db0c86edcc97b4526a67e1b8a 391 Gene3D G3DSA:3.40.47.10 142 193 3.4E-58 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS04950 c7b4b19db0c86edcc97b4526a67e1b8a 391 Gene3D G3DSA:3.40.47.10 276 390 3.4E-58 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS04950 c7b4b19db0c86edcc97b4526a67e1b8a 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 389 1.3E-134 T 22-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 HRM2_RS04950 c7b4b19db0c86edcc97b4526a67e1b8a 391 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 22-04-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 HRM2_RS04950 c7b4b19db0c86edcc97b4526a67e1b8a 391 SUPERFAMILY SSF53901 4 268 5.26E-82 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS04950 c7b4b19db0c86edcc97b4526a67e1b8a 391 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 22-04-2016 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 Reactome: REACT_22258 HRM2_RS04950 c7b4b19db0c86edcc97b4526a67e1b8a 391 PIRSF PIRSF000429 1 391 2.0E-118 T 22-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 HRM2_RS04950 c7b4b19db0c86edcc97b4526a67e1b8a 391 Pfam PF00108 Thiolase, N-terminal domain 5 261 9.5E-95 T 22-04-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 HRM2_RS04950 c7b4b19db0c86edcc97b4526a67e1b8a 391 SUPERFAMILY SSF53901 271 390 2.31E-35 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS04950 c7b4b19db0c86edcc97b4526a67e1b8a 391 ProSitePatterns PS00099 Thiolases active site. 373 386 - T 22-04-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 HRM2_RS04950 c7b4b19db0c86edcc97b4526a67e1b8a 391 PANTHER PTHR18919:SF95 1 391 2.6E-191 T 22-04-2016 HRM2_RS19510 48fcdf6e1ec65a8cff68b8761651a8b4 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 1.5E-5 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS19510 48fcdf6e1ec65a8cff68b8761651a8b4 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 1.5E-5 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS19510 48fcdf6e1ec65a8cff68b8761651a8b4 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 1.5E-5 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS19510 48fcdf6e1ec65a8cff68b8761651a8b4 149 SUPERFAMILY SSF46785 6 143 4.42E-30 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS19510 48fcdf6e1ec65a8cff68b8761651a8b4 149 Gene3D G3DSA:1.10.10.10 6 141 4.6E-33 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS19510 48fcdf6e1ec65a8cff68b8761651a8b4 149 SMART SM00347 26 126 3.3E-17 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS19510 48fcdf6e1ec65a8cff68b8761651a8b4 149 ProSitePatterns PS01117 MarR-type HTH domain signature. 65 99 - T 22-04-2016 IPR023187 Transcriptional regulator MarR-type, conserved site HRM2_RS19510 48fcdf6e1ec65a8cff68b8761651a8b4 149 Pfam PF01047 MarR family 37 90 9.6E-14 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS19510 48fcdf6e1ec65a8cff68b8761651a8b4 149 PANTHER PTHR33164 6 141 3.5E-22 T 22-04-2016 HRM2_RS00770 13e38045d17be432919484f18161d34d 133 Pfam PF00384 Molybdopterin oxidoreductase 58 133 3.3E-14 T 22-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 HRM2_RS00770 13e38045d17be432919484f18161d34d 133 SUPERFAMILY SSF53706 2 133 1.44E-51 T 22-04-2016 HRM2_RS00770 13e38045d17be432919484f18161d34d 133 SMART SM00926 1 55 4.4E-21 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS00770 13e38045d17be432919484f18161d34d 133 PANTHER PTHR11615 1 133 3.6E-42 T 22-04-2016 HRM2_RS00770 13e38045d17be432919484f18161d34d 133 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 1 55 3.0E-19 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS00770 13e38045d17be432919484f18161d34d 133 Gene3D G3DSA:3.40.50.740 58 130 3.5E-26 T 22-04-2016 HRM2_RS00770 13e38045d17be432919484f18161d34d 133 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 6 24 - T 22-04-2016 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 HRM2_RS00770 13e38045d17be432919484f18161d34d 133 PANTHER PTHR11615:SF112 1 133 3.6E-42 T 22-04-2016 HRM2_RS00770 13e38045d17be432919484f18161d34d 133 Gene3D G3DSA:2.20.25.90 1 57 2.8E-23 T 22-04-2016 HRM2_RS00315 a23b8caaa97d626695502d01076219e0 1226 PANTHER PTHR11615:SF35 692 827 0.0 T 22-04-2016 HRM2_RS00315 a23b8caaa97d626695502d01076219e0 1226 PANTHER PTHR11615 843 867 0.0 T 22-04-2016 HRM2_RS00315 a23b8caaa97d626695502d01076219e0 1226 Gene3D G3DSA:2.20.25.90 55 100 7.0E-27 T 22-04-2016 HRM2_RS00315 a23b8caaa97d626695502d01076219e0 1226 Gene3D G3DSA:2.40.40.20 1045 1224 4.8E-37 T 22-04-2016 HRM2_RS00315 a23b8caaa97d626695502d01076219e0 1226 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 1 1225 0.0 T 22-04-2016 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 HRM2_RS00315 a23b8caaa97d626695502d01076219e0 1226 Pfam PF14710 Respiratory nitrate reductase alpha N-terminal 1 43 3.6E-14 T 22-04-2016 IPR028189 Nitrate reductase, alpha subunit, N-terminal KEGG: 00910+1.7.99.4 HRM2_RS00315 a23b8caaa97d626695502d01076219e0 1226 Pfam PF01568 Molydopterin dinucleotide binding domain 1078 1192 2.1E-19 T 22-04-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 HRM2_RS00315 a23b8caaa97d626695502d01076219e0 1226 PANTHER PTHR11615:SF35 843 867 0.0 T 22-04-2016 HRM2_RS00315 a23b8caaa97d626695502d01076219e0 1226 Pfam PF00384 Molybdopterin oxidoreductase 111 824 5.4E-146 T 22-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 HRM2_RS00315 a23b8caaa97d626695502d01076219e0 1226 PANTHER PTHR11615 986 1219 0.0 T 22-04-2016 HRM2_RS00315 a23b8caaa97d626695502d01076219e0 1226 PANTHER PTHR11615:SF35 37 413 0.0 T 22-04-2016 HRM2_RS00315 a23b8caaa97d626695502d01076219e0 1226 PANTHER PTHR11615:SF35 986 1219 0.0 T 22-04-2016 HRM2_RS00315 a23b8caaa97d626695502d01076219e0 1226 SMART SM00926 46 108 7.9E-7 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS00315 a23b8caaa97d626695502d01076219e0 1226 Gene3D G3DSA:3.40.50.740 111 120 6.8E-74 T 22-04-2016 HRM2_RS00315 a23b8caaa97d626695502d01076219e0 1226 Gene3D G3DSA:3.40.50.740 639 668 6.8E-74 T 22-04-2016 HRM2_RS00315 a23b8caaa97d626695502d01076219e0 1226 Gene3D G3DSA:3.40.50.740 1026 1037 6.8E-74 T 22-04-2016 HRM2_RS00315 a23b8caaa97d626695502d01076219e0 1226 Gene3D G3DSA:3.40.50.740 930 972 6.8E-74 T 22-04-2016 HRM2_RS00315 a23b8caaa97d626695502d01076219e0 1226 Gene3D G3DSA:3.40.50.740 701 826 6.8E-74 T 22-04-2016 HRM2_RS00315 a23b8caaa97d626695502d01076219e0 1226 Gene3D G3DSA:3.40.50.740 157 224 6.8E-74 T 22-04-2016 HRM2_RS00315 a23b8caaa97d626695502d01076219e0 1226 Gene3D G3DSA:3.40.50.740 561 586 6.8E-74 T 22-04-2016 HRM2_RS00315 a23b8caaa97d626695502d01076219e0 1226 Gene3D G3DSA:3.40.228.10 225 339 5.2E-59 T 22-04-2016 HRM2_RS00315 a23b8caaa97d626695502d01076219e0 1226 Gene3D G3DSA:3.40.228.10 484 560 5.2E-59 T 22-04-2016 HRM2_RS00315 a23b8caaa97d626695502d01076219e0 1226 PANTHER PTHR11615 692 827 0.0 T 22-04-2016 HRM2_RS00315 a23b8caaa97d626695502d01076219e0 1226 PANTHER PTHR11615 37 413 0.0 T 22-04-2016 HRM2_RS00315 a23b8caaa97d626695502d01076219e0 1226 SUPERFAMILY SSF50692 1069 1224 3.62E-43 T 22-04-2016 IPR009010 Aspartate decarboxylase-like domain HRM2_RS00315 a23b8caaa97d626695502d01076219e0 1226 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 51 69 - T 22-04-2016 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 HRM2_RS00315 a23b8caaa97d626695502d01076219e0 1226 SUPERFAMILY SSF53706 22 1058 0.0 T 22-04-2016 HRM2_RS18350 98686d66540a9dfac34ae0b91c8f608e 326 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 254 322 1.3E-13 T 22-04-2016 IPR001543 Surface presentation of antigen (SpoA) HRM2_RS18350 98686d66540a9dfac34ae0b91c8f608e 326 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 3 323 8.5E-97 T 22-04-2016 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HRM2_RS18350 98686d66540a9dfac34ae0b91c8f608e 326 Gene3D G3DSA:2.30.330.10 245 319 1.1E-9 T 22-04-2016 HRM2_RS18350 98686d66540a9dfac34ae0b91c8f608e 326 SUPERFAMILY SSF101801 249 321 1.14E-10 T 22-04-2016 IPR001543 Surface presentation of antigen (SpoA) HRM2_RS18350 98686d66540a9dfac34ae0b91c8f608e 326 SUPERFAMILY SSF103039 56 231 2.2E-15 T 22-04-2016 IPR028976 CheC-like domain HRM2_RS18350 98686d66540a9dfac34ae0b91c8f608e 326 Pfam PF02154 Flagellar motor switch protein FliM 39 231 2.9E-64 T 22-04-2016 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HRM2_RS18350 98686d66540a9dfac34ae0b91c8f608e 326 Gene3D G3DSA:3.40.1550.10 67 231 8.3E-5 T 22-04-2016 IPR028976 CheC-like domain HRM2_RS18350 98686d66540a9dfac34ae0b91c8f608e 326 PANTHER PTHR30034:SF0 1 323 5.7E-117 T 22-04-2016 HRM2_RS18350 98686d66540a9dfac34ae0b91c8f608e 326 PRINTS PR00955 Flagellar motor switch protein FliM signature 213 231 6.6E-25 T 22-04-2016 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HRM2_RS18350 98686d66540a9dfac34ae0b91c8f608e 326 PRINTS PR00955 Flagellar motor switch protein FliM signature 2 15 6.6E-25 T 22-04-2016 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HRM2_RS18350 98686d66540a9dfac34ae0b91c8f608e 326 PRINTS PR00955 Flagellar motor switch protein FliM signature 90 106 6.6E-25 T 22-04-2016 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HRM2_RS18350 98686d66540a9dfac34ae0b91c8f608e 326 PRINTS PR00955 Flagellar motor switch protein FliM signature 115 134 6.6E-25 T 22-04-2016 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HRM2_RS18350 98686d66540a9dfac34ae0b91c8f608e 326 PANTHER PTHR30034 1 323 5.7E-117 T 22-04-2016 HRM2_RS18350 98686d66540a9dfac34ae0b91c8f608e 326 PIRSF PIRSF002888 1 325 3.0E-99 T 22-04-2016 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HRM2_RS01800 41c243d2b6a67d947ca0d29d8815c9d3 662 Pfam PF02954 Bacterial regulatory protein, Fis family 614 649 1.4E-7 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS01800 41c243d2b6a67d947ca0d29d8815c9d3 662 Gene3D G3DSA:1.10.10.60 601 649 1.8E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS01800 41c243d2b6a67d947ca0d29d8815c9d3 662 SMART SM00382 356 500 2.8E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS01800 41c243d2b6a67d947ca0d29d8815c9d3 662 Pfam PF00158 Sigma-54 interaction domain 338 503 3.6E-60 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS01800 41c243d2b6a67d947ca0d29d8815c9d3 662 Gene3D G3DSA:1.10.8.60 510 583 1.5E-19 T 22-04-2016 HRM2_RS01800 41c243d2b6a67d947ca0d29d8815c9d3 662 Gene3D G3DSA:3.40.50.300 332 508 1.5E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01800 41c243d2b6a67d947ca0d29d8815c9d3 662 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 423 438 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS01800 41c243d2b6a67d947ca0d29d8815c9d3 662 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 360 373 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS01800 41c243d2b6a67d947ca0d29d8815c9d3 662 Gene3D G3DSA:3.30.450.20 209 263 1.1E-4 T 22-04-2016 HRM2_RS01800 41c243d2b6a67d947ca0d29d8815c9d3 662 SUPERFAMILY SSF52540 336 570 5.64E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01800 41c243d2b6a67d947ca0d29d8815c9d3 662 PANTHER PTHR32071 307 660 2.5E-128 T 22-04-2016 HRM2_RS01800 41c243d2b6a67d947ca0d29d8815c9d3 662 SUPERFAMILY SSF46689 550 650 1.51E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS10145 76e56cd655f72d9c2e86545de36e816d 428 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 236 272 - T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HRM2_RS10145 76e56cd655f72d9c2e86545de36e816d 428 PANTHER PTHR11986 1 427 2.1E-217 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HRM2_RS10145 76e56cd655f72d9c2e86545de36e816d 428 SUPERFAMILY SSF53383 2 424 8.35E-134 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS10145 76e56cd655f72d9c2e86545de36e816d 428 Pfam PF00202 Aminotransferase class-III 35 404 2.3E-79 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HRM2_RS10145 76e56cd655f72d9c2e86545de36e816d 428 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 6 425 1.7E-192 T 22-04-2016 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188|UniPathway: UPA00251 HRM2_RS10145 76e56cd655f72d9c2e86545de36e816d 428 PANTHER PTHR11986:SF5 1 427 2.1E-217 T 22-04-2016 HRM2_RS10145 76e56cd655f72d9c2e86545de36e816d 428 Gene3D G3DSA:3.40.640.10 72 318 7.3E-82 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS10145 76e56cd655f72d9c2e86545de36e816d 428 Gene3D G3DSA:3.90.1150.10 321 425 2.5E-46 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS10145 76e56cd655f72d9c2e86545de36e816d 428 Gene3D G3DSA:3.90.1150.10 2 71 2.5E-46 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS10145 76e56cd655f72d9c2e86545de36e816d 428 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 5 427 103.748 T 22-04-2016 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188|UniPathway: UPA00251 HRM2_RS16135 3a995670a2637ec5dacfa23e7155ff73 204 Pfam PF10050 Predicted metal-binding protein (DUF2284) 23 193 1.9E-35 T 22-04-2016 IPR019271 Protein of unknown function DUF2284, metal-binding HRM2_RS23445 536b4503304e496330d4468c7c28c9ab 564 PANTHER PTHR16254 359 518 5.1E-29 T 22-04-2016 HRM2_RS23445 536b4503304e496330d4468c7c28c9ab 564 SUPERFAMILY SSF116726 268 345 9.42E-10 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS23445 536b4503304e496330d4468c7c28c9ab 564 Gene3D G3DSA:1.10.287.70 15 102 8.0E-16 T 22-04-2016 HRM2_RS23445 536b4503304e496330d4468c7c28c9ab 564 Pfam PF07885 Ion channel 31 101 3.3E-8 T 22-04-2016 IPR013099 Potassium channel domain HRM2_RS23445 536b4503304e496330d4468c7c28c9ab 564 Pfam PF02080 TrkA-C domain 286 342 2.4E-7 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS23445 536b4503304e496330d4468c7c28c9ab 564 Pfam PF02080 TrkA-C domain 505 561 3.5E-7 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS23445 536b4503304e496330d4468c7c28c9ab 564 Gene3D G3DSA:3.40.50.720 359 481 5.3E-31 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS23445 536b4503304e496330d4468c7c28c9ab 564 Gene3D G3DSA:3.40.50.720 127 260 1.7E-19 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS23445 536b4503304e496330d4468c7c28c9ab 564 SUPERFAMILY SSF51735 129 261 1.18E-15 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS23445 536b4503304e496330d4468c7c28c9ab 564 Pfam PF02254 TrkA-N domain 138 245 4.3E-11 T 22-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 HRM2_RS23445 536b4503304e496330d4468c7c28c9ab 564 Pfam PF02254 TrkA-N domain 359 468 1.1E-25 T 22-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 HRM2_RS23445 536b4503304e496330d4468c7c28c9ab 564 SUPERFAMILY SSF116726 502 563 1.7E-11 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS23445 536b4503304e496330d4468c7c28c9ab 564 SUPERFAMILY SSF51735 359 486 1.84E-28 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS23445 536b4503304e496330d4468c7c28c9ab 564 Gene3D G3DSA:3.30.70.1450 286 345 5.5E-9 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS23445 536b4503304e496330d4468c7c28c9ab 564 Gene3D G3DSA:3.30.70.1450 502 562 1.5E-12 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS23445 536b4503304e496330d4468c7c28c9ab 564 SUPERFAMILY SSF81324 16 152 1.05E-19 T 22-04-2016 HRM2_RS09820 094483eeae1ae483b49bdb559604e098 288 Pfam PF01522 Polysaccharide deacetylase 6 151 3.8E-20 T 22-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 HRM2_RS09820 094483eeae1ae483b49bdb559604e098 288 Pfam PF11959 Domain of unknown function (DUF3473) 153 286 7.3E-37 T 22-04-2016 IPR022560 Domain of unknown function DUF3473 HRM2_RS09820 094483eeae1ae483b49bdb559604e098 288 Gene3D G3DSA:3.20.20.370 12 268 1.6E-40 T 22-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 HRM2_RS09820 094483eeae1ae483b49bdb559604e098 288 SUPERFAMILY SSF88713 13 253 9.64E-41 T 22-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 HRM2_RS09820 094483eeae1ae483b49bdb559604e098 288 TIGRFAM TIGR03006 pepcterm_polyde: polysaccharide deacetylase family protein, PEP-CTERM locus subfamily 14 276 1.6E-86 T 22-04-2016 IPR014344 PEP-CTERM locus, polysaccharide deactylase HRM2_RS09820 094483eeae1ae483b49bdb559604e098 288 PANTHER PTHR10587:SF85 36 154 1.2E-25 T 22-04-2016 HRM2_RS09820 094483eeae1ae483b49bdb559604e098 288 PANTHER PTHR10587 36 154 1.2E-25 T 22-04-2016 HRM2_RS04485 092414bea5422201a9202f0d6ac5e01d 595 Pfam PF00672 HAMP domain 233 299 3.6E-14 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS04485 092414bea5422201a9202f0d6ac5e01d 595 Pfam PF11845 Protein of unknown function (DUF3365) 20 215 4.7E-33 T 22-04-2016 IPR021796 Protein of unknown function DUF3365 HRM2_RS04485 092414bea5422201a9202f0d6ac5e01d 595 SMART SM00283 332 593 1.5E-53 T 22-04-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HRM2_RS04485 092414bea5422201a9202f0d6ac5e01d 595 SMART SM00304 251 303 6.3E-9 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS04485 092414bea5422201a9202f0d6ac5e01d 595 Gene3D G3DSA:1.10.287.950 341 549 8.7E-49 T 22-04-2016 HRM2_RS04485 092414bea5422201a9202f0d6ac5e01d 595 SUPERFAMILY SSF58104 271 592 1.44E-64 T 22-04-2016 HRM2_RS04485 092414bea5422201a9202f0d6ac5e01d 595 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 393 592 4.0E-34 T 22-04-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HRM2_RS04485 092414bea5422201a9202f0d6ac5e01d 595 PANTHER PTHR32089 199 595 1.7E-96 T 22-04-2016 HRM2_RS03055 8940102659caf37634b5cc17cf5a074d 375 PANTHER PTHR35806 1 375 4.5E-177 T 22-04-2016 HRM2_RS03055 8940102659caf37634b5cc17cf5a074d 375 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 21 369 3.9E-149 T 22-04-2016 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 HRM2_RS03055 8940102659caf37634b5cc17cf5a074d 375 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 21 373 3.4E-154 T 22-04-2016 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 HRM2_RS03055 8940102659caf37634b5cc17cf5a074d 375 PIRSF PIRSF015658 1 375 1.7E-161 T 22-04-2016 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 HRM2_RS25380 b15b0e686edf0223265d5bfd65cc5f04 549 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 229 408 1.1E-25 T 22-04-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain HRM2_RS25380 b15b0e686edf0223265d5bfd65cc5f04 549 Gene3D G3DSA:3.40.50.300 225 466 1.6E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS25380 b15b0e686edf0223265d5bfd65cc5f04 549 SUPERFAMILY SSF52540 226 468 6.32E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS25380 b15b0e686edf0223265d5bfd65cc5f04 549 SUPERFAMILY SSF160246 46 189 4.18E-16 T 22-04-2016 HRM2_RS25380 b15b0e686edf0223265d5bfd65cc5f04 549 PANTHER PTHR13696:SF3 221 477 1.0E-79 T 22-04-2016 HRM2_RS25380 b15b0e686edf0223265d5bfd65cc5f04 549 PANTHER PTHR13696 221 477 1.0E-79 T 22-04-2016 HRM2_RS07795 0fdb56d3509c156f554d3fcbc9d47ece 443 Gene3D G3DSA:3.80.30.20 197 393 1.6E-25 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe HRM2_RS07795 0fdb56d3509c156f554d3fcbc9d47ece 443 SMART SM00729 193 411 1.1E-13 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS07795 0fdb56d3509c156f554d3fcbc9d47ece 443 PANTHER PTHR11918:SF64 19 393 2.5E-41 T 22-04-2016 HRM2_RS07795 0fdb56d3509c156f554d3fcbc9d47ece 443 PANTHER PTHR11918 19 393 2.5E-41 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein HRM2_RS07795 0fdb56d3509c156f554d3fcbc9d47ece 443 Pfam PF02310 B12 binding domain 16 137 2.2E-11 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS07795 0fdb56d3509c156f554d3fcbc9d47ece 443 SUPERFAMILY SSF102114 197 405 1.31E-26 T 22-04-2016 HRM2_RS07795 0fdb56d3509c156f554d3fcbc9d47ece 443 Pfam PF04055 Radical SAM superfamily 201 358 9.4E-13 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS12910 be23af7425f9c9bf492dc9e20274be19 929 Pfam PF07796 Protein of unknown function (DUF1638) 34 218 9.2E-40 T 22-04-2016 IPR012437 Domain of unknown function DUF1638 HRM2_RS12910 be23af7425f9c9bf492dc9e20274be19 929 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 280 438 2.5E-27 T 22-04-2016 IPR008040 Hydantoinaseoxoprolinase, N-terminal HRM2_RS12910 be23af7425f9c9bf492dc9e20274be19 929 Pfam PF01968 Hydantoinase/oxoprolinase 458 602 6.0E-35 T 22-04-2016 IPR002821 Hydantoinase/oxoprolinase GO:0016787 HRM2_RS12910 be23af7425f9c9bf492dc9e20274be19 929 SUPERFAMILY SSF53067 516 565 2.62E-8 T 22-04-2016 HRM2_RS12910 be23af7425f9c9bf492dc9e20274be19 929 SUPERFAMILY SSF53067 391 431 2.62E-8 T 22-04-2016 HRM2_RS12910 be23af7425f9c9bf492dc9e20274be19 929 SUPERFAMILY SSF53067 279 308 2.62E-8 T 22-04-2016 HRM2_RS12910 be23af7425f9c9bf492dc9e20274be19 929 PANTHER PTHR11365 272 602 1.6E-70 T 22-04-2016 HRM2_RS20645 31c6ef382196775b6c727dc103edd1e6 857 Gene3D G3DSA:3.30.565.10 695 851 4.0E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS20645 31c6ef382196775b6c727dc103edd1e6 857 SMART SM00388 627 693 2.9E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS20645 31c6ef382196775b6c727dc103edd1e6 857 SMART SM00091 496 562 8.3E-7 T 22-04-2016 IPR000014 PAS domain HRM2_RS20645 31c6ef382196775b6c727dc103edd1e6 857 SMART SM00091 368 437 0.0011 T 22-04-2016 IPR000014 PAS domain HRM2_RS20645 31c6ef382196775b6c727dc103edd1e6 857 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 380 491 6.8E-8 T 22-04-2016 IPR000014 PAS domain HRM2_RS20645 31c6ef382196775b6c727dc103edd1e6 857 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 494 619 1.7E-13 T 22-04-2016 IPR000014 PAS domain HRM2_RS20645 31c6ef382196775b6c727dc103edd1e6 857 SMART SM00387 735 855 3.2E-19 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS20645 31c6ef382196775b6c727dc103edd1e6 857 SUPERFAMILY SSF55785 381 492 6.11E-14 T 22-04-2016 IPR000014 PAS domain HRM2_RS20645 31c6ef382196775b6c727dc103edd1e6 857 Pfam PF13426 PAS domain 385 482 1.7E-10 T 22-04-2016 IPR000014 PAS domain HRM2_RS20645 31c6ef382196775b6c727dc103edd1e6 857 PRINTS PR00344 Bacterial sensor protein C-terminal signature 804 814 2.1E-9 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS20645 31c6ef382196775b6c727dc103edd1e6 857 PRINTS PR00344 Bacterial sensor protein C-terminal signature 816 834 2.1E-9 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS20645 31c6ef382196775b6c727dc103edd1e6 857 PRINTS PR00344 Bacterial sensor protein C-terminal signature 786 800 2.1E-9 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS20645 31c6ef382196775b6c727dc103edd1e6 857 SUPERFAMILY SSF55874 693 851 8.12E-27 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS20645 31c6ef382196775b6c727dc103edd1e6 857 SUPERFAMILY SSF55785 482 609 4.54E-17 T 22-04-2016 IPR000014 PAS domain HRM2_RS20645 31c6ef382196775b6c727dc103edd1e6 857 Gene3D G3DSA:1.10.287.130 623 689 2.1E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS20645 31c6ef382196775b6c727dc103edd1e6 857 Pfam PF00512 His Kinase A (phospho-acceptor) domain 629 689 5.9E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS20645 31c6ef382196775b6c727dc103edd1e6 857 Pfam PF00989 PAS fold 496 605 3.0E-6 T 22-04-2016 IPR013767 PAS fold GO:0006355 HRM2_RS20645 31c6ef382196775b6c727dc103edd1e6 857 SUPERFAMILY SSF47384 621 690 2.16E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS20645 31c6ef382196775b6c727dc103edd1e6 857 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 737 838 1.3E-12 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS20645 31c6ef382196775b6c727dc103edd1e6 857 Gene3D G3DSA:3.30.450.20 482 609 1.1E-17 T 22-04-2016 HRM2_RS20645 31c6ef382196775b6c727dc103edd1e6 857 Gene3D G3DSA:3.30.450.20 347 480 5.0E-14 T 22-04-2016 HRM2_RS20645 31c6ef382196775b6c727dc103edd1e6 857 PANTHER PTHR24423 770 844 4.3E-71 T 22-04-2016 HRM2_RS20645 31c6ef382196775b6c727dc103edd1e6 857 PANTHER PTHR24423 381 754 4.3E-71 T 22-04-2016 HRM2_RS12210 c2334d343e9ca9f7197e32cc254ae696 279 PANTHER PTHR11825 5 271 9.2E-59 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 HRM2_RS12210 c2334d343e9ca9f7197e32cc254ae696 279 Pfam PF01063 Amino-transferase class IV 30 248 4.8E-49 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 HRM2_RS12210 c2334d343e9ca9f7197e32cc254ae696 279 SUPERFAMILY SSF56752 3 272 5.1E-63 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 HRM2_RS12210 c2334d343e9ca9f7197e32cc254ae696 279 Gene3D G3DSA:3.30.470.10 3 114 6.5E-25 T 22-04-2016 HRM2_RS12210 c2334d343e9ca9f7197e32cc254ae696 279 Gene3D G3DSA:3.20.10.10 121 271 3.2E-41 T 22-04-2016 HRM2_RS12210 c2334d343e9ca9f7197e32cc254ae696 279 PANTHER PTHR11825:SF7 5 271 9.2E-59 T 22-04-2016 HRM2_RS20705 7204d832fa80a8d02dbdd3a01e03cbc8 192 SUPERFAMILY SSF47240 4 147 3.95E-40 T 22-04-2016 IPR009078 Ferritin-like superfamily HRM2_RS20705 7204d832fa80a8d02dbdd3a01e03cbc8 192 SUPERFAMILY SSF57802 149 192 1.56E-10 T 22-04-2016 HRM2_RS20705 7204d832fa80a8d02dbdd3a01e03cbc8 192 PANTHER PTHR33746 1 187 5.1E-97 T 22-04-2016 HRM2_RS20705 7204d832fa80a8d02dbdd3a01e03cbc8 192 Gene3D G3DSA:2.20.28.10 148 192 3.3E-19 T 22-04-2016 IPR004039 Rubredoxin-type fold HRM2_RS20705 7204d832fa80a8d02dbdd3a01e03cbc8 192 Gene3D G3DSA:1.20.1260.10 2 146 1.8E-57 T 22-04-2016 IPR012347 Ferritin-related HRM2_RS20705 7204d832fa80a8d02dbdd3a01e03cbc8 192 PANTHER PTHR33746:SF1 1 187 5.1E-97 T 22-04-2016 HRM2_RS20705 7204d832fa80a8d02dbdd3a01e03cbc8 192 Pfam PF02915 Rubrerythrin 11 139 5.3E-33 T 22-04-2016 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 HRM2_RS06395 a949297812f2fc2c87e01b488f4ade2a 463 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 88 97 - T 22-04-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 HRM2_RS06395 a949297812f2fc2c87e01b488f4ade2a 463 Gene3D G3DSA:3.30.70.360 212 365 4.4E-31 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain HRM2_RS06395 a949297812f2fc2c87e01b488f4ade2a 463 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 131 170 - T 22-04-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 HRM2_RS06395 a949297812f2fc2c87e01b488f4ade2a 463 Gene3D G3DSA:3.40.630.10 374 461 3.9E-42 T 22-04-2016 HRM2_RS06395 a949297812f2fc2c87e01b488f4ade2a 463 Gene3D G3DSA:3.40.630.10 17 204 3.9E-42 T 22-04-2016 HRM2_RS06395 a949297812f2fc2c87e01b488f4ade2a 463 Pfam PF07687 Peptidase dimerisation domain 222 355 1.8E-5 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain HRM2_RS06395 a949297812f2fc2c87e01b488f4ade2a 463 SUPERFAMILY SSF53187 375 461 3.43E-46 T 22-04-2016 HRM2_RS06395 a949297812f2fc2c87e01b488f4ade2a 463 SUPERFAMILY SSF53187 16 210 3.43E-46 T 22-04-2016 HRM2_RS06395 a949297812f2fc2c87e01b488f4ade2a 463 PANTHER PTHR11014:SF72 292 463 5.3E-80 T 22-04-2016 HRM2_RS06395 a949297812f2fc2c87e01b488f4ade2a 463 PANTHER PTHR11014:SF72 37 256 5.3E-80 T 22-04-2016 HRM2_RS06395 a949297812f2fc2c87e01b488f4ade2a 463 PANTHER PTHR11014 292 463 5.3E-80 T 22-04-2016 HRM2_RS06395 a949297812f2fc2c87e01b488f4ade2a 463 PANTHER PTHR11014 37 256 5.3E-80 T 22-04-2016 HRM2_RS06395 a949297812f2fc2c87e01b488f4ade2a 463 Pfam PF01546 Peptidase family M20/M25/M40 89 450 1.6E-21 T 22-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 HRM2_RS03035 42b68da2ac35a41058127e67c13e1060 326 SUPERFAMILY SSF55729 153 313 1.69E-46 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS03035 42b68da2ac35a41058127e67c13e1060 326 Gene3D G3DSA:3.40.630.30 24 147 5.8E-39 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS03035 42b68da2ac35a41058127e67c13e1060 326 Gene3D G3DSA:3.40.630.30 148 305 7.2E-53 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS03035 42b68da2ac35a41058127e67c13e1060 326 PIRSF PIRSF018688 21 315 7.3E-73 T 22-04-2016 IPR016732 Uncharacterised conserved protein UCP018688 HRM2_RS03035 42b68da2ac35a41058127e67c13e1060 326 SUPERFAMILY SSF55729 24 152 1.06E-25 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS03035 42b68da2ac35a41058127e67c13e1060 326 PANTHER PTHR41373 19 305 1.1E-59 T 22-04-2016 HRM2_RS03035 42b68da2ac35a41058127e67c13e1060 326 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 47 303 4.7E-35 T 22-04-2016 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal HRM2_RS05770 724e8c482a058d25ddffc1ce10c70a7a 152 PANTHER PTHR30302 3 150 1.9E-33 T 22-04-2016 HRM2_RS05770 724e8c482a058d25ddffc1ce10c70a7a 152 SUPERFAMILY SSF53163 2 149 1.28E-36 T 22-04-2016 IPR023430 Peptidase HybD-like domain HRM2_RS05770 724e8c482a058d25ddffc1ce10c70a7a 152 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 5 146 2.1E-38 T 22-04-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 HRM2_RS05770 724e8c482a058d25ddffc1ce10c70a7a 152 PRINTS PR00446 Hydrogen uptake protein signature 67 83 7.9E-16 T 22-04-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 HRM2_RS05770 724e8c482a058d25ddffc1ce10c70a7a 152 PRINTS PR00446 Hydrogen uptake protein signature 16 27 7.9E-16 T 22-04-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 HRM2_RS05770 724e8c482a058d25ddffc1ce10c70a7a 152 PRINTS PR00446 Hydrogen uptake protein signature 4 16 7.9E-16 T 22-04-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 HRM2_RS05770 724e8c482a058d25ddffc1ce10c70a7a 152 PRINTS PR00446 Hydrogen uptake protein signature 35 52 7.9E-16 T 22-04-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 HRM2_RS05770 724e8c482a058d25ddffc1ce10c70a7a 152 PRINTS PR00446 Hydrogen uptake protein signature 56 66 7.9E-16 T 22-04-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 HRM2_RS05770 724e8c482a058d25ddffc1ce10c70a7a 152 Pfam PF01750 Hydrogenase maturation protease 21 143 1.0E-22 T 22-04-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 HRM2_RS05770 724e8c482a058d25ddffc1ce10c70a7a 152 PANTHER PTHR30302:SF1 3 150 1.9E-33 T 22-04-2016 HRM2_RS05770 724e8c482a058d25ddffc1ce10c70a7a 152 Gene3D G3DSA:3.40.50.1450 2 150 2.8E-42 T 22-04-2016 IPR023430 Peptidase HybD-like domain HRM2_RS00385 ad36c2a267caee95f9bb01e00671145e 439 PANTHER PTHR11921 30 414 3.3E-50 T 22-04-2016 HRM2_RS00385 ad36c2a267caee95f9bb01e00671145e 439 Pfam PF02754 Cysteine-rich domain 297 388 1.5E-10 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS00385 ad36c2a267caee95f9bb01e00671145e 439 SUPERFAMILY SSF46548 29 104 5.93E-15 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS00385 ad36c2a267caee95f9bb01e00671145e 439 Gene3D G3DSA:3.30.70.20 353 382 8.5E-4 T 22-04-2016 HRM2_RS00385 ad36c2a267caee95f9bb01e00671145e 439 Pfam PF13183 4Fe-4S dicluster domain 30 91 9.7E-9 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS00385 ad36c2a267caee95f9bb01e00671145e 439 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 33 44 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS00385 ad36c2a267caee95f9bb01e00671145e 439 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 77 88 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS00385 ad36c2a267caee95f9bb01e00671145e 439 PANTHER PTHR11921:SF24 30 414 3.3E-50 T 22-04-2016 HRM2_RS00385 ad36c2a267caee95f9bb01e00671145e 439 Gene3D G3DSA:1.10.1060.10 21 103 2.0E-12 T 22-04-2016 HRM2_RS02185 867038b90386cad17159d4e7ca72bda7 358 PANTHER PTHR11835:SF35 2 358 1.7E-190 T 22-04-2016 HRM2_RS02185 867038b90386cad17159d4e7ca72bda7 358 SMART SM01329 4 354 9.4E-205 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 HRM2_RS02185 867038b90386cad17159d4e7ca72bda7 358 PANTHER PTHR11835 2 358 1.7E-190 T 22-04-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 HRM2_RS02185 867038b90386cad17159d4e7ca72bda7 358 SUPERFAMILY SSF53659 2 358 6.91E-126 T 22-04-2016 HRM2_RS02185 867038b90386cad17159d4e7ca72bda7 358 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 245 264 - T 22-04-2016 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 HRM2_RS02185 867038b90386cad17159d4e7ca72bda7 358 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 4 353 7.1E-157 T 22-04-2016 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396|UniPathway: UPA00048 HRM2_RS02185 867038b90386cad17159d4e7ca72bda7 358 Gene3D G3DSA:3.40.718.10 2 358 4.1E-131 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 HRM2_RS02185 867038b90386cad17159d4e7ca72bda7 358 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 358 49.446 T 22-04-2016 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396|UniPathway: UPA00048 HRM2_RS02185 867038b90386cad17159d4e7ca72bda7 358 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 354 7.0E-134 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 HRM2_RS19110 ae572e3e0403680b7a32bfddc8282ce2 169 PANTHER PTHR35011 1 160 2.8E-19 T 22-04-2016 HRM2_RS19110 ae572e3e0403680b7a32bfddc8282ce2 169 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 30 160 6.2E-27 T 22-04-2016 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component HRM2_RS01370 40eb5bd5b6ac17665793861134c1a637 276 Pfam PF01513 ATP-NAD kinase 50 254 9.9E-57 T 22-04-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 HRM2_RS01370 40eb5bd5b6ac17665793861134c1a637 276 PANTHER PTHR20275 52 272 2.3E-75 T 22-04-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 HRM2_RS01370 40eb5bd5b6ac17665793861134c1a637 276 Gene3D G3DSA:2.60.200.30 126 247 4.9E-43 T 22-04-2016 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 HRM2_RS01370 40eb5bd5b6ac17665793861134c1a637 276 Gene3D G3DSA:3.40.50.10330 10 125 1.4E-26 T 22-04-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 HRM2_RS01370 40eb5bd5b6ac17665793861134c1a637 276 Hamap MF_00361 NAD kinase [nadK]. 3 271 30.195 T 22-04-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 HRM2_RS01370 40eb5bd5b6ac17665793861134c1a637 276 SUPERFAMILY SSF111331 11 272 5.1E-79 T 22-04-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain HRM2_RS23980 c240bcca79b5883abb08baecbbd63e2d 153 Gene3D G3DSA:2.60.40.790 14 151 1.7E-39 T 22-04-2016 IPR008978 HSP20-like chaperone HRM2_RS23980 c240bcca79b5883abb08baecbbd63e2d 153 Pfam PF00011 Hsp20/alpha crystallin family 50 150 1.1E-21 T 22-04-2016 IPR002068 Alpha crystallin/Hsp20 domain HRM2_RS23980 c240bcca79b5883abb08baecbbd63e2d 153 PANTHER PTHR11527 14 151 7.8E-33 T 22-04-2016 IPR031107 Small heat shock protein HSP20 HRM2_RS23980 c240bcca79b5883abb08baecbbd63e2d 153 SUPERFAMILY SSF49764 25 148 9.42E-36 T 22-04-2016 IPR008978 HSP20-like chaperone HRM2_RS23980 c240bcca79b5883abb08baecbbd63e2d 153 PANTHER PTHR11527:SF122 14 151 7.8E-33 T 22-04-2016 HRM2_RS23675 43e380dd5b3871ad974042d66ae58678 519 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 11 502 21.755 T 22-04-2016 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 UniPathway: UPA00666 HRM2_RS23675 43e380dd5b3871ad974042d66ae58678 519 SUPERFAMILY SSF56317 233 492 3.53E-53 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 HRM2_RS23675 43e380dd5b3871ad974042d66ae58678 519 Gene3D G3DSA:3.60.110.10 228 482 2.5E-42 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 HRM2_RS23675 43e380dd5b3871ad974042d66ae58678 519 Pfam PF00795 Carbon-nitrogen hydrolase 235 483 8.8E-35 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 HRM2_RS23675 43e380dd5b3871ad974042d66ae58678 519 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 65 465 5.0E-109 T 22-04-2016 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 UniPathway: UPA00666 HRM2_RS23675 43e380dd5b3871ad974042d66ae58678 519 PANTHER PTHR38686 3 519 4.5E-80 T 22-04-2016 HRM2_RS12565 9a271bb092ae216338de73f3b2da4097 182 Gene3D G3DSA:2.60.120.10 1 179 1.5E-80 T 22-04-2016 IPR014710 RmlC-like jelly roll fold HRM2_RS12565 9a271bb092ae216338de73f3b2da4097 182 SUPERFAMILY SSF51182 1 179 5.71E-77 T 22-04-2016 IPR011051 RmlC-like cupin domain HRM2_RS12565 9a271bb092ae216338de73f3b2da4097 182 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 175 4.7E-74 T 22-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 HRM2_RS12565 9a271bb092ae216338de73f3b2da4097 182 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 4 178 3.6E-82 T 22-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 HRM2_RS12565 9a271bb092ae216338de73f3b2da4097 182 PANTHER PTHR21047 1 181 7.6E-74 T 22-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 HRM2_RS12565 9a271bb092ae216338de73f3b2da4097 182 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 181 9.0E-66 T 22-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 HRM2_RS07470 141888713a1f1619e5937c780861eb22 382 Pfam PF03235 Protein of unknown function DUF262 62 197 1.0E-14 T 22-04-2016 IPR004919 Domain of unknown function DUF262 HRM2_RS07470 141888713a1f1619e5937c780861eb22 382 PANTHER PTHR39639 43 216 3.2E-20 T 22-04-2016 HRM2_RS07690 7ae52ec16866a4bf34b9b655aa2b551c 434 SUPERFAMILY SSF81340 10 422 1.44E-103 T 22-04-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 HRM2_RS07690 7ae52ec16866a4bf34b9b655aa2b551c 434 PRINTS PR00762 Chloride channel signature 324 344 1.8E-24 T 22-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HRM2_RS07690 7ae52ec16866a4bf34b9b655aa2b551c 434 PRINTS PR00762 Chloride channel signature 377 396 1.8E-24 T 22-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HRM2_RS07690 7ae52ec16866a4bf34b9b655aa2b551c 434 PRINTS PR00762 Chloride channel signature 158 177 1.8E-24 T 22-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HRM2_RS07690 7ae52ec16866a4bf34b9b655aa2b551c 434 PRINTS PR00762 Chloride channel signature 80 97 1.8E-24 T 22-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HRM2_RS07690 7ae52ec16866a4bf34b9b655aa2b551c 434 PRINTS PR00762 Chloride channel signature 359 375 1.8E-24 T 22-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HRM2_RS07690 7ae52ec16866a4bf34b9b655aa2b551c 434 PANTHER PTHR11689:SF96 1 420 1.4E-111 T 22-04-2016 HRM2_RS07690 7ae52ec16866a4bf34b9b655aa2b551c 434 PANTHER PTHR11689 1 420 1.4E-111 T 22-04-2016 HRM2_RS07690 7ae52ec16866a4bf34b9b655aa2b551c 434 Gene3D G3DSA:1.10.3080.10 17 423 1.1E-99 T 22-04-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 HRM2_RS07690 7ae52ec16866a4bf34b9b655aa2b551c 434 Pfam PF00654 Voltage gated chloride channel 68 409 2.4E-93 T 22-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HRM2_RS22430 b4515673bfdd7ce27b554deb49059ad1 299 SUPERFAMILY SSF161098 92 282 3.79E-29 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS22430 b4515673bfdd7ce27b554deb49059ad1 299 Gene3D G3DSA:1.10.3720.10 91 295 2.0E-28 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS22430 b4515673bfdd7ce27b554deb49059ad1 299 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 17 68 6.6E-13 T 22-04-2016 IPR025966 Oligopeptide transport permease C-like, N-terminal domain HRM2_RS22430 b4515673bfdd7ce27b554deb49059ad1 299 PANTHER PTHR30465 9 299 2.8E-128 T 22-04-2016 HRM2_RS22430 b4515673bfdd7ce27b554deb49059ad1 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 298 2.8E-30 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS22430 b4515673bfdd7ce27b554deb49059ad1 299 PANTHER PTHR30465:SF10 9 299 2.8E-128 T 22-04-2016 HRM2_RS11650 98301a8680b687ea7ff80ec889c83aea 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 2.7E-29 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HRM2_RS11650 98301a8680b687ea7ff80ec889c83aea 66 PANTHER PTHR11544 1 66 3.0E-36 T 22-04-2016 HRM2_RS11650 98301a8680b687ea7ff80ec889c83aea 66 SUPERFAMILY SSF50249 1 65 5.9E-24 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS11650 98301a8680b687ea7ff80ec889c83aea 66 PIRSF PIRSF002599 1 66 1.5E-23 T 22-04-2016 IPR012156 Cold shock, CspA GO:0003676 HRM2_RS11650 98301a8680b687ea7ff80ec889c83aea 66 SMART SM00357 3 66 6.3E-31 T 22-04-2016 IPR011129 Cold shock protein GO:0003676 HRM2_RS11650 98301a8680b687ea7ff80ec889c83aea 66 Gene3D G3DSA:2.40.50.140 1 65 5.4E-31 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS11650 98301a8680b687ea7ff80ec889c83aea 66 PRINTS PR00050 Cold shock protein signature 24 33 1.7E-17 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HRM2_RS11650 98301a8680b687ea7ff80ec889c83aea 66 PRINTS PR00050 Cold shock protein signature 39 57 1.7E-17 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HRM2_RS11650 98301a8680b687ea7ff80ec889c83aea 66 PRINTS PR00050 Cold shock protein signature 4 19 1.7E-17 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HRM2_RS11650 98301a8680b687ea7ff80ec889c83aea 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 22-04-2016 IPR019844 Cold-shock conserved site HRM2_RS00460 2d4f7e5c164fd101b8851184f73673c0 194 Gene3D G3DSA:3.40.50.150 23 179 2.2E-25 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS00460 2d4f7e5c164fd101b8851184f73673c0 194 PANTHER PTHR10108 21 181 9.9E-19 T 22-04-2016 HRM2_RS00460 2d4f7e5c164fd101b8851184f73673c0 194 SUPERFAMILY SSF53335 21 180 1.24E-28 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS00460 2d4f7e5c164fd101b8851184f73673c0 194 Pfam PF01209 ubiE/COQ5 methyltransferase family 24 148 1.2E-14 T 22-04-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 HRM2_RS10170 7bb991cd19a1fbe812c9618332e136ce 497 PANTHER PTHR33525 221 488 2.7E-16 T 22-04-2016 HRM2_RS10170 7bb991cd19a1fbe812c9618332e136ce 497 Pfam PF08668 HDOD domain 222 407 3.9E-22 T 22-04-2016 IPR013976 Metal-dependent hydrolase HDOD HRM2_RS10170 7bb991cd19a1fbe812c9618332e136ce 497 SUPERFAMILY SSF109604 211 471 4.24E-29 T 22-04-2016 HRM2_RS10170 7bb991cd19a1fbe812c9618332e136ce 497 Gene3D G3DSA:1.10.3150.10 212 470 4.8E-31 T 22-04-2016 IPR013976 Metal-dependent hydrolase HDOD HRM2_RS10170 7bb991cd19a1fbe812c9618332e136ce 497 Gene3D G3DSA:1.10.460.10 39 153 3.1E-4 T 22-04-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 HRM2_RS10170 7bb991cd19a1fbe812c9618332e136ce 497 PANTHER PTHR33525:SF3 221 488 2.7E-16 T 22-04-2016 HRM2_RS15095 e6dcfaefcc9dfb05269b07acd44f6e1c 140 Pfam PF02472 Biopolymer transport protein ExbD/TolR 12 134 9.2E-32 T 22-04-2016 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 HRM2_RS15095 e6dcfaefcc9dfb05269b07acd44f6e1c 140 TIGRFAM TIGR02801 tolR: protein TolR 14 133 6.0E-38 T 22-04-2016 IPR014168 Biopolymer transport, TolR GO:0015031|GO:0016021 HRM2_RS15095 e6dcfaefcc9dfb05269b07acd44f6e1c 140 PANTHER PTHR30558:SF7 12 140 3.0E-35 T 22-04-2016 HRM2_RS15095 e6dcfaefcc9dfb05269b07acd44f6e1c 140 PANTHER PTHR30558 12 140 3.0E-35 T 22-04-2016 HRM2_RS05395 49d5ef70b3b0ae1c4f254bd284588106 723 Pfam PF07664 Ferrous iron transport protein B C terminus 462 514 3.5E-22 T 22-04-2016 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 HRM2_RS05395 49d5ef70b3b0ae1c4f254bd284588106 723 Gene3D G3DSA:3.40.50.300 2 167 8.0E-35 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05395 49d5ef70b3b0ae1c4f254bd284588106 723 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 27 45 8.4E-7 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS05395 49d5ef70b3b0ae1c4f254bd284588106 723 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 6 26 8.4E-7 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS05395 49d5ef70b3b0ae1c4f254bd284588106 723 Pfam PF07670 Nucleoside recognition 519 691 8.3E-32 T 22-04-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 HRM2_RS05395 49d5ef70b3b0ae1c4f254bd284588106 723 Pfam PF07670 Nucleoside recognition 358 452 1.4E-13 T 22-04-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 HRM2_RS05395 49d5ef70b3b0ae1c4f254bd284588106 723 PANTHER PTHR11649 1 146 2.9E-261 T 22-04-2016 HRM2_RS05395 49d5ef70b3b0ae1c4f254bd284588106 723 PANTHER PTHR11649 274 546 2.9E-261 T 22-04-2016 HRM2_RS05395 49d5ef70b3b0ae1c4f254bd284588106 723 PANTHER PTHR11649 595 720 2.9E-261 T 22-04-2016 HRM2_RS05395 49d5ef70b3b0ae1c4f254bd284588106 723 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 10 689 2.1E-196 T 22-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 HRM2_RS05395 49d5ef70b3b0ae1c4f254bd284588106 723 PANTHER PTHR11649:SF37 1 146 2.9E-261 T 22-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 HRM2_RS05395 49d5ef70b3b0ae1c4f254bd284588106 723 PANTHER PTHR11649:SF37 274 546 2.9E-261 T 22-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 HRM2_RS05395 49d5ef70b3b0ae1c4f254bd284588106 723 PANTHER PTHR11649:SF37 595 720 2.9E-261 T 22-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 HRM2_RS05395 49d5ef70b3b0ae1c4f254bd284588106 723 Pfam PF02421 Ferrous iron transport protein B 5 157 1.5E-64 T 22-04-2016 IPR011619 Ferrous iron transport protein B, N-terminal GO:0005525|GO:0015093|GO:0015684|GO:0016021 HRM2_RS05395 49d5ef70b3b0ae1c4f254bd284588106 723 SUPERFAMILY SSF52540 4 164 2.75E-39 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS15435 0ba22d01b1f0933ed393165d410d19aa 222 SUPERFAMILY SSF63380 2 92 1.19E-24 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 HRM2_RS15435 0ba22d01b1f0933ed393165d410d19aa 222 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 2 197 9.8E-62 T 22-04-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 HRM2_RS15435 0ba22d01b1f0933ed393165d410d19aa 222 PIRSF PIRSF000498 1 208 1.1E-68 T 22-04-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 HRM2_RS15435 0ba22d01b1f0933ed393165d410d19aa 222 PANTHER PTHR21098:SF0 2 221 2.2E-83 T 22-04-2016 HRM2_RS15435 0ba22d01b1f0933ed393165d410d19aa 222 Pfam PF00677 Lumazine binding domain 99 183 1.8E-19 T 22-04-2016 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 HRM2_RS15435 0ba22d01b1f0933ed393165d410d19aa 222 Pfam PF00677 Lumazine binding domain 3 86 2.2E-21 T 22-04-2016 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 HRM2_RS15435 0ba22d01b1f0933ed393165d410d19aa 222 SUPERFAMILY SSF63380 92 197 1.62E-29 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 HRM2_RS15435 0ba22d01b1f0933ed393165d410d19aa 222 PANTHER PTHR21098 2 221 2.2E-83 T 22-04-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 HRM2_RS15435 0ba22d01b1f0933ed393165d410d19aa 222 Gene3D G3DSA:2.40.30.20 5 103 5.4E-31 T 22-04-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS15435 0ba22d01b1f0933ed393165d410d19aa 222 Gene3D G3DSA:2.40.30.20 104 201 8.9E-29 T 22-04-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS02420 5bcbe32136fdb57f8ad19b1bff622669 385 SUPERFAMILY SSF54373 243 317 7.32E-6 T 22-04-2016 HRM2_RS02420 5bcbe32136fdb57f8ad19b1bff622669 385 Gene3D G3DSA:3.30.9.10 221 316 1.7E-10 T 22-04-2016 HRM2_RS02420 5bcbe32136fdb57f8ad19b1bff622669 385 Gene3D G3DSA:3.30.9.10 88 140 1.7E-10 T 22-04-2016 HRM2_RS02420 5bcbe32136fdb57f8ad19b1bff622669 385 Gene3D G3DSA:3.50.50.60 1 82 5.5E-43 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS02420 5bcbe32136fdb57f8ad19b1bff622669 385 Gene3D G3DSA:3.50.50.60 317 364 5.5E-43 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS02420 5bcbe32136fdb57f8ad19b1bff622669 385 Gene3D G3DSA:3.50.50.60 141 220 5.5E-43 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS02420 5bcbe32136fdb57f8ad19b1bff622669 385 PANTHER PTHR13847 5 376 1.0E-50 T 22-04-2016 HRM2_RS02420 5bcbe32136fdb57f8ad19b1bff622669 385 SUPERFAMILY SSF51905 5 221 3.56E-48 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS02420 5bcbe32136fdb57f8ad19b1bff622669 385 SUPERFAMILY SSF51905 317 377 3.56E-48 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS02420 5bcbe32136fdb57f8ad19b1bff622669 385 Pfam PF01266 FAD dependent oxidoreductase 6 356 1.8E-48 T 22-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 HRM2_RS19900 ecb96991d4b996ac57988e3dd7f492b5 708 PANTHER PTHR11814:SF71 367 703 5.4E-179 T 22-04-2016 HRM2_RS19900 ecb96991d4b996ac57988e3dd7f492b5 708 PANTHER PTHR11814:SF71 1 234 5.4E-179 T 22-04-2016 HRM2_RS19900 ecb96991d4b996ac57988e3dd7f492b5 708 Pfam PF01740 STAS domain 584 682 5.0E-16 T 22-04-2016 IPR002645 STAS domain HRM2_RS19900 ecb96991d4b996ac57988e3dd7f492b5 708 PANTHER PTHR11814 367 703 5.4E-179 T 22-04-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Reactome: REACT_15518 HRM2_RS19900 ecb96991d4b996ac57988e3dd7f492b5 708 PANTHER PTHR11814 1 234 5.4E-179 T 22-04-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Reactome: REACT_15518 HRM2_RS19900 ecb96991d4b996ac57988e3dd7f492b5 708 Pfam PF00916 Sulfate permease family 20 251 1.3E-53 T 22-04-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 HRM2_RS19900 ecb96991d4b996ac57988e3dd7f492b5 708 Pfam PF00916 Sulfate permease family 361 522 1.4E-46 T 22-04-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 HRM2_RS19900 ecb96991d4b996ac57988e3dd7f492b5 708 Gene3D G3DSA:3.30.750.24 576 686 1.4E-18 T 22-04-2016 IPR002645 STAS domain HRM2_RS19900 ecb96991d4b996ac57988e3dd7f492b5 708 SUPERFAMILY SSF52091 574 683 3.34E-17 T 22-04-2016 IPR002645 STAS domain HRM2_RS14265 fc69417a75c7aead81e78c4aaf753f95 287 PANTHER PTHR22981 1 282 1.2E-136 T 22-04-2016 HRM2_RS14265 fc69417a75c7aead81e78c4aaf753f95 287 SUPERFAMILY SSF51735 3 163 2.73E-40 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS14265 fc69417a75c7aead81e78c4aaf753f95 287 Gene3D G3DSA:3.40.50.720 3 161 2.4E-46 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS14265 fc69417a75c7aead81e78c4aaf753f95 287 Gene3D G3DSA:1.10.1040.10 165 287 1.1E-33 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HRM2_RS14265 fc69417a75c7aead81e78c4aaf753f95 287 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 283 7.2E-25 T 22-04-2016 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 HRM2_RS14265 fc69417a75c7aead81e78c4aaf753f95 287 SUPERFAMILY SSF48179 164 287 4.53E-32 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HRM2_RS14265 fc69417a75c7aead81e78c4aaf753f95 287 PIRSF PIRSF000103 1 287 2.4E-85 T 22-04-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 HRM2_RS14265 fc69417a75c7aead81e78c4aaf753f95 287 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 159 6.9E-39 T 22-04-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 HRM2_RS14265 fc69417a75c7aead81e78c4aaf753f95 287 PANTHER PTHR22981:SF53 1 282 1.2E-136 T 22-04-2016 HRM2_RS13895 deb3275354ef8cfc4f289b45756f0e95 218 Pfam PF00072 Response regulator receiver domain 8 119 1.1E-26 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS13895 deb3275354ef8cfc4f289b45756f0e95 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 5.8E-19 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS13895 deb3275354ef8cfc4f289b45756f0e95 218 SUPERFAMILY SSF52172 4 184 2.34E-31 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS13895 deb3275354ef8cfc4f289b45756f0e95 218 PANTHER PTHR26402:SF151 6 218 4.7E-63 T 22-04-2016 HRM2_RS13895 deb3275354ef8cfc4f289b45756f0e95 218 SMART SM00448 6 119 5.9E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS13895 deb3275354ef8cfc4f289b45756f0e95 218 Gene3D G3DSA:1.10.10.10 125 216 1.7E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS13895 deb3275354ef8cfc4f289b45756f0e95 218 SMART SM00421 153 210 2.9E-19 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS13895 deb3275354ef8cfc4f289b45756f0e95 218 Gene3D G3DSA:3.40.50.2300 5 124 1.3E-32 T 22-04-2016 HRM2_RS13895 deb3275354ef8cfc4f289b45756f0e95 218 PANTHER PTHR26402 6 218 4.7E-63 T 22-04-2016 HRM2_RS13895 deb3275354ef8cfc4f289b45756f0e95 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS13895 deb3275354ef8cfc4f289b45756f0e95 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 1.3E-12 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS13895 deb3275354ef8cfc4f289b45756f0e95 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 1.3E-12 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS13895 deb3275354ef8cfc4f289b45756f0e95 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 1.3E-12 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS06030 fb1b05a12b9cc254dfb84e204dc169a2 368 Pfam PF01546 Peptidase family M20/M25/M40 69 356 7.5E-21 T 22-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 HRM2_RS06030 fb1b05a12b9cc254dfb84e204dc169a2 368 Gene3D G3DSA:3.30.70.360 185 269 1.4E-25 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain HRM2_RS06030 fb1b05a12b9cc254dfb84e204dc169a2 368 Pfam PF07687 Peptidase dimerisation domain 173 267 2.4E-15 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain HRM2_RS06030 fb1b05a12b9cc254dfb84e204dc169a2 368 SUPERFAMILY SSF55031 176 271 4.04E-18 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain HRM2_RS06030 fb1b05a12b9cc254dfb84e204dc169a2 368 SUPERFAMILY SSF53187 2 175 1.75E-39 T 22-04-2016 HRM2_RS06030 fb1b05a12b9cc254dfb84e204dc169a2 368 SUPERFAMILY SSF53187 282 355 1.75E-39 T 22-04-2016 HRM2_RS06030 fb1b05a12b9cc254dfb84e204dc169a2 368 Gene3D G3DSA:3.40.630.10 301 357 3.2E-55 T 22-04-2016 HRM2_RS06030 fb1b05a12b9cc254dfb84e204dc169a2 368 Gene3D G3DSA:3.40.630.10 3 184 3.2E-55 T 22-04-2016 HRM2_RS06030 fb1b05a12b9cc254dfb84e204dc169a2 368 PANTHER PTHR11014 3 364 4.3E-56 T 22-04-2016 HRM2_RS23595 862dc1679b8e6317dada8669eb6adc78 267 PANTHER PTHR22769 97 251 9.5E-63 T 22-04-2016 HRM2_RS23595 862dc1679b8e6317dada8669eb6adc78 267 PANTHER PTHR22769:SF7 97 251 9.5E-63 T 22-04-2016 HRM2_RS23595 862dc1679b8e6317dada8669eb6adc78 267 SUPERFAMILY SSF55811 93 247 9.07E-44 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HRM2_RS23595 862dc1679b8e6317dada8669eb6adc78 267 Gene3D G3DSA:3.90.79.10 102 263 8.3E-45 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HRM2_RS23595 862dc1679b8e6317dada8669eb6adc78 267 SUPERFAMILY SSF55811 9 108 1.37E-11 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HRM2_RS23595 862dc1679b8e6317dada8669eb6adc78 267 Pfam PF00293 NUDIX domain 140 258 1.6E-21 T 22-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 HRM2_RS23595 862dc1679b8e6317dada8669eb6adc78 267 Hamap MF_00297 NADH pyrophosphatase [nudC]. 5 267 38.232 T 22-04-2016 IPR022925 NADH pyrophosphatase NudC GO:0000210 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 HRM2_RS23595 862dc1679b8e6317dada8669eb6adc78 267 ProSitePatterns PS00893 Nudix box signature. 171 192 - T 22-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 HRM2_RS23595 862dc1679b8e6317dada8669eb6adc78 267 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 107 136 7.5E-8 T 22-04-2016 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 HRM2_RS23595 862dc1679b8e6317dada8669eb6adc78 267 PRINTS PR00502 NUDIX hydrolase family signature 180 195 8.4E-5 T 22-04-2016 IPR020476 NUDIX hydrolase HRM2_RS23595 862dc1679b8e6317dada8669eb6adc78 267 PRINTS PR00502 NUDIX hydrolase family signature 166 180 8.4E-5 T 22-04-2016 IPR020476 NUDIX hydrolase HRM2_RS01975 1f5adb2064acf662fd2c8cec492bb26e 239 Gene3D G3DSA:2.50.20.10 62 231 2.5E-41 T 22-04-2016 HRM2_RS01975 1f5adb2064acf662fd2c8cec492bb26e 239 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 63 224 1.7E-25 T 22-04-2016 IPR004564 Outer membrane lipoprotein carrier protein LolA-like HRM2_RS01975 1f5adb2064acf662fd2c8cec492bb26e 239 PANTHER PTHR35869 21 238 2.3E-32 T 22-04-2016 HRM2_RS01975 1f5adb2064acf662fd2c8cec492bb26e 239 SUPERFAMILY SSF89392 61 231 7.06E-33 T 22-04-2016 IPR029046 Lipoprotein localisation LolA/LolB/LppX HRM2_RS13580 c0a38b2decc725753c93fa71935223e3 282 PANTHER PTHR24322:SF513 29 158 5.8E-26 T 22-04-2016 HRM2_RS13580 c0a38b2decc725753c93fa71935223e3 282 PANTHER PTHR24322:SF513 174 205 5.8E-26 T 22-04-2016 HRM2_RS13580 c0a38b2decc725753c93fa71935223e3 282 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 31 274 2.5E-29 T 22-04-2016 HRM2_RS13580 c0a38b2decc725753c93fa71935223e3 282 Gene3D G3DSA:3.40.50.720 25 275 9.3E-47 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS13580 c0a38b2decc725753c93fa71935223e3 282 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 161 189 - T 22-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 HRM2_RS13580 c0a38b2decc725753c93fa71935223e3 282 SUPERFAMILY SSF51735 26 276 4.67E-44 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS13580 c0a38b2decc725753c93fa71935223e3 282 PANTHER PTHR24322 29 158 5.8E-26 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS13580 c0a38b2decc725753c93fa71935223e3 282 PANTHER PTHR24322 174 205 5.8E-26 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS13580 c0a38b2decc725753c93fa71935223e3 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 211 4.1E-13 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS13580 c0a38b2decc725753c93fa71935223e3 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 164 4.1E-13 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS13580 c0a38b2decc725753c93fa71935223e3 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 193 4.1E-13 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS13580 c0a38b2decc725753c93fa71935223e3 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 99 110 4.1E-13 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS13580 c0a38b2decc725753c93fa71935223e3 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 26 43 4.1E-13 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS09755 f7dda83ff29b67823f56af87fc30606c 548 PANTHER PTHR32309 351 510 1.2E-40 T 22-04-2016 HRM2_RS09755 f7dda83ff29b67823f56af87fc30606c 548 PANTHER PTHR32309 15 326 1.2E-40 T 22-04-2016 HRM2_RS09755 f7dda83ff29b67823f56af87fc30606c 548 PANTHER PTHR32309:SF13 351 510 1.2E-40 T 22-04-2016 HRM2_RS09755 f7dda83ff29b67823f56af87fc30606c 548 PANTHER PTHR32309:SF13 15 326 1.2E-40 T 22-04-2016 HRM2_RS09755 f7dda83ff29b67823f56af87fc30606c 548 Pfam PF13807 G-rich domain on putative tyrosine kinase 388 469 1.5E-9 T 22-04-2016 IPR032807 Tyrosine kinase, G-rich domain HRM2_RS09755 f7dda83ff29b67823f56af87fc30606c 548 Pfam PF02706 Chain length determinant protein 15 157 1.7E-11 T 22-04-2016 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 HRM2_RS11415 d6feffbe0339646e7d69c1cb0e8f24ca 248 SMART SM00079 25 245 7.9E-9 T 22-04-2016 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 HRM2_RS11415 d6feffbe0339646e7d69c1cb0e8f24ca 248 SMART SM00062 25 246 1.0E-71 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS11415 d6feffbe0339646e7d69c1cb0e8f24ca 248 PANTHER PTHR18966 26 243 3.2E-57 T 22-04-2016 HRM2_RS11415 d6feffbe0339646e7d69c1cb0e8f24ca 248 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 49 62 - T 22-04-2016 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 HRM2_RS11415 d6feffbe0339646e7d69c1cb0e8f24ca 248 Gene3D G3DSA:3.40.190.10 104 207 8.8E-31 T 22-04-2016 HRM2_RS11415 d6feffbe0339646e7d69c1cb0e8f24ca 248 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 26 244 2.6E-69 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS11415 d6feffbe0339646e7d69c1cb0e8f24ca 248 Gene3D G3DSA:3.40.190.10 208 246 1.6E-45 T 22-04-2016 HRM2_RS11415 d6feffbe0339646e7d69c1cb0e8f24ca 248 Gene3D G3DSA:3.40.190.10 24 103 1.6E-45 T 22-04-2016 HRM2_RS11415 d6feffbe0339646e7d69c1cb0e8f24ca 248 SUPERFAMILY SSF53850 1 245 1.26E-75 T 22-04-2016 HRM2_RS24800 54014c39410074193d2c2495aaae95a0 282 Gene3D G3DSA:1.20.141.10 37 203 9.9E-53 T 22-04-2016 HRM2_RS24800 54014c39410074193d2c2495aaae95a0 282 Pfam PF01471 Putative peptidoglycan binding domain 240 278 1.8E-9 T 22-04-2016 IPR002477 Peptidoglycan binding-like HRM2_RS24800 54014c39410074193d2c2495aaae95a0 282 Pfam PF05838 Glycosyl hydrolase 108 45 128 2.2E-27 T 22-04-2016 IPR008565 Protein of unknown function DUF847 HRM2_RS24800 54014c39410074193d2c2495aaae95a0 282 SUPERFAMILY SSF53955 37 198 3.37E-49 T 22-04-2016 IPR023346 Lysozyme-like domain HRM2_RS24800 54014c39410074193d2c2495aaae95a0 282 Pfam PF09374 Predicted Peptidoglycan domain 132 193 7.8E-8 T 22-04-2016 IPR018537 Peptidoglycan binding domain HRM2_RS24800 54014c39410074193d2c2495aaae95a0 282 SUPERFAMILY SSF47090 218 279 1.65E-13 T 22-04-2016 IPR002477 Peptidoglycan binding-like HRM2_RS24800 54014c39410074193d2c2495aaae95a0 282 Gene3D G3DSA:1.10.101.10 219 278 8.6E-14 T 22-04-2016 IPR002477 Peptidoglycan binding-like HRM2_RS11990 ab6a2a524cf0fa690e1e7e8a3a16bab0 217 Gene3D G3DSA:3.40.50.360 4 209 1.7E-36 T 22-04-2016 IPR029039 Flavoprotein-like domain HRM2_RS11990 ab6a2a524cf0fa690e1e7e8a3a16bab0 217 PANTHER PTHR10204 3 154 7.9E-21 T 22-04-2016 HRM2_RS11990 ab6a2a524cf0fa690e1e7e8a3a16bab0 217 SUPERFAMILY SSF52218 4 156 1.12E-27 T 22-04-2016 IPR029039 Flavoprotein-like domain HRM2_RS11990 ab6a2a524cf0fa690e1e7e8a3a16bab0 217 Pfam PF03358 NADPH-dependent FMN reductase 4 135 7.7E-16 T 22-04-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 HRM2_RS11990 ab6a2a524cf0fa690e1e7e8a3a16bab0 217 PANTHER PTHR10204:SF5 3 154 7.9E-21 T 22-04-2016 HRM2_RS10990 a102abc03a5a48843e5162c3d4ad8bc4 246 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 5 241 4.6E-57 T 22-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS10990 a102abc03a5a48843e5162c3d4ad8bc4 246 Pfam PF01416 tRNA pseudouridine synthase 149 246 3.3E-24 T 22-04-2016 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS10990 a102abc03a5a48843e5162c3d4ad8bc4 246 Pfam PF01416 tRNA pseudouridine synthase 10 104 2.7E-8 T 22-04-2016 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS10990 a102abc03a5a48843e5162c3d4ad8bc4 246 PANTHER PTHR11142:SF0 2 246 3.4E-79 T 22-04-2016 HRM2_RS10990 a102abc03a5a48843e5162c3d4ad8bc4 246 Gene3D G3DSA:3.30.70.660 108 244 2.3E-40 T 22-04-2016 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS10990 a102abc03a5a48843e5162c3d4ad8bc4 246 Gene3D G3DSA:3.30.70.580 2 106 4.4E-37 T 22-04-2016 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS10990 a102abc03a5a48843e5162c3d4ad8bc4 246 PANTHER PTHR11142 2 246 3.4E-79 T 22-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS10990 a102abc03a5a48843e5162c3d4ad8bc4 246 PIRSF PIRSF001430 2 246 1.4E-76 T 22-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS10990 a102abc03a5a48843e5162c3d4ad8bc4 246 SUPERFAMILY SSF55120 3 246 2.16E-77 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS10990 a102abc03a5a48843e5162c3d4ad8bc4 246 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 3 246 33.584 T 22-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS03345 809045dca296c64f969f5e3bf6763667 325 SUPERFAMILY SSF51161 121 305 9.29E-42 T 22-04-2016 IPR011004 Trimeric LpxA-like HRM2_RS03345 809045dca296c64f969f5e3bf6763667 325 Gene3D G3DSA:1.10.3130.10 56 195 2.3E-38 T 22-04-2016 HRM2_RS03345 809045dca296c64f969f5e3bf6763667 325 PANTHER PTHR23416 70 325 4.5E-85 T 22-04-2016 HRM2_RS03345 809045dca296c64f969f5e3bf6763667 325 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 261 296 0.0016 T 22-04-2016 IPR001451 Hexapeptide repeat HRM2_RS03345 809045dca296c64f969f5e3bf6763667 325 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 222 244 0.0018 T 22-04-2016 IPR001451 Hexapeptide repeat HRM2_RS03345 809045dca296c64f969f5e3bf6763667 325 Gene3D G3DSA:2.160.10.10 196 318 1.5E-26 T 22-04-2016 HRM2_RS03345 809045dca296c64f969f5e3bf6763667 325 PANTHER PTHR23416:SF65 70 325 4.5E-85 T 22-04-2016 HRM2_RS15870 1d3cdb7b7b0da34aab5f7383627fcbc4 308 PANTHER PTHR11135 1 307 3.4E-133 T 22-04-2016 HRM2_RS15870 1d3cdb7b7b0da34aab5f7383627fcbc4 308 Pfam PF04055 Radical SAM superfamily 32 205 5.8E-13 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS15870 1d3cdb7b7b0da34aab5f7383627fcbc4 308 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 6 305 4.7E-115 T 22-04-2016 IPR005911 Protein YhcC-like GO:0051536 HRM2_RS15870 1d3cdb7b7b0da34aab5f7383627fcbc4 308 PANTHER PTHR11135:SF1 1 307 3.4E-133 T 22-04-2016 IPR005911 Protein YhcC-like GO:0051536 HRM2_RS15870 1d3cdb7b7b0da34aab5f7383627fcbc4 308 SMART SM00729 23 250 3.8E-38 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS15870 1d3cdb7b7b0da34aab5f7383627fcbc4 308 Pfam PF16199 Radical_SAM C-terminal domain 211 285 9.2E-24 T 22-04-2016 IPR032432 Radical SAM, C-terminal extension HRM2_RS15870 1d3cdb7b7b0da34aab5f7383627fcbc4 308 Gene3D G3DSA:3.80.30.20 24 251 1.6E-31 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe HRM2_RS15870 1d3cdb7b7b0da34aab5f7383627fcbc4 308 SUPERFAMILY SSF102114 9 298 1.57E-46 T 22-04-2016 HRM2_RS12325 88fd7b9d2b14c731a303256fa77591e7 202 PANTHER PTHR17490:SF7 1 199 1.2E-80 T 22-04-2016 HRM2_RS12325 88fd7b9d2b14c731a303256fa77591e7 202 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 6 196 9.7E-62 T 22-04-2016 IPR006070 YrdC-like domain GO:0003725 HRM2_RS12325 88fd7b9d2b14c731a303256fa77591e7 202 Gene3D G3DSA:3.90.870.10 2 199 2.7E-62 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain HRM2_RS12325 88fd7b9d2b14c731a303256fa77591e7 202 PANTHER PTHR17490 1 199 1.2E-80 T 22-04-2016 HRM2_RS12325 88fd7b9d2b14c731a303256fa77591e7 202 SUPERFAMILY SSF55821 2 200 3.66E-60 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain HRM2_RS12325 88fd7b9d2b14c731a303256fa77591e7 202 Pfam PF01300 Telomere recombination 21 194 2.5E-49 T 22-04-2016 IPR006070 YrdC-like domain GO:0003725 HRM2_RS01220 79a68379775a58b10d8642ad0d075153 106 Gene3D G3DSA:1.20.120.160 3 97 1.2E-13 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HRM2_RS01220 79a68379775a58b10d8642ad0d075153 106 Pfam PF01627 Hpt domain 19 99 1.4E-11 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HRM2_RS01220 79a68379775a58b10d8642ad0d075153 106 SUPERFAMILY SSF47226 2 102 1.06E-15 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HRM2_RS01220 79a68379775a58b10d8642ad0d075153 106 SMART SM00073 9 104 9.1E-7 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HRM2_RS23970 ad9b6b61208fc26b2e869cc8952e75c7 305 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 22 153 1.9E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS23970 ad9b6b61208fc26b2e869cc8952e75c7 305 SUPERFAMILY SSF55785 18 144 7.33E-8 T 22-04-2016 IPR000014 PAS domain HRM2_RS23970 ad9b6b61208fc26b2e869cc8952e75c7 305 SMART SM00421 242 299 1.6E-17 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS23970 ad9b6b61208fc26b2e869cc8952e75c7 305 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 245 259 7.2E-10 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS23970 ad9b6b61208fc26b2e869cc8952e75c7 305 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 275 287 7.2E-10 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS23970 ad9b6b61208fc26b2e869cc8952e75c7 305 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 259 275 7.2E-10 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS23970 ad9b6b61208fc26b2e869cc8952e75c7 305 PANTHER PTHR24423 22 155 3.5E-14 T 22-04-2016 HRM2_RS23970 ad9b6b61208fc26b2e869cc8952e75c7 305 Pfam PF08448 PAS fold 30 147 1.8E-5 T 22-04-2016 IPR013656 PAS fold-4 HRM2_RS23970 ad9b6b61208fc26b2e869cc8952e75c7 305 Gene3D G3DSA:1.10.10.10 244 294 1.8E-17 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS23970 ad9b6b61208fc26b2e869cc8952e75c7 305 PANTHER PTHR24423:SF552 22 155 3.5E-14 T 22-04-2016 HRM2_RS23970 ad9b6b61208fc26b2e869cc8952e75c7 305 ProSitePatterns PS00622 LuxR-type HTH domain signature. 259 286 - T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS23970 ad9b6b61208fc26b2e869cc8952e75c7 305 SUPERFAMILY SSF46894 233 294 1.05E-15 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HRM2_RS23970 ad9b6b61208fc26b2e869cc8952e75c7 305 Gene3D G3DSA:3.30.450.20 21 144 2.3E-11 T 22-04-2016 HRM2_RS23970 ad9b6b61208fc26b2e869cc8952e75c7 305 Pfam PF00196 Bacterial regulatory proteins, luxR family 244 294 1.2E-16 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS05020 a61dd4c8fe52a4511bfa9a4e2a0ddcab 300 PANTHER PTHR32120 1 286 8.2E-69 T 22-04-2016 HRM2_RS05020 a61dd4c8fe52a4511bfa9a4e2a0ddcab 300 Gene3D G3DSA:1.10.40.50 228 290 2.3E-20 T 22-04-2016 HRM2_RS05020 a61dd4c8fe52a4511bfa9a4e2a0ddcab 300 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 50 286 4.3E-47 T 22-04-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 HRM2_RS05020 a61dd4c8fe52a4511bfa9a4e2a0ddcab 300 SUPERFAMILY SSF52540 68 287 2.53E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05020 a61dd4c8fe52a4511bfa9a4e2a0ddcab 300 Pfam PF03193 Protein of unknown function, DUF258 53 226 6.1E-33 T 22-04-2016 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 HRM2_RS05020 a61dd4c8fe52a4511bfa9a4e2a0ddcab 300 Gene3D G3DSA:3.40.50.300 68 226 2.5E-32 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05020 a61dd4c8fe52a4511bfa9a4e2a0ddcab 300 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 5 293 26.782 T 22-04-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 HRM2_RS04960 0025478858efa89ff542db6f4cce3d34 399 SUPERFAMILY SSF53092 20 141 1.15E-18 T 22-04-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal HRM2_RS04960 0025478858efa89ff542db6f4cce3d34 399 SUPERFAMILY SSF55920 140 398 4.06E-49 T 22-04-2016 IPR000994 Peptidase M24, structural domain HRM2_RS04960 0025478858efa89ff542db6f4cce3d34 399 Pfam PF01321 Creatinase/Prolidase N-terminal domain 16 141 3.3E-16 T 22-04-2016 IPR000587 Creatinase, N-terminal GO:0016787 HRM2_RS04960 0025478858efa89ff542db6f4cce3d34 399 PANTHER PTHR10804 27 397 5.1E-67 T 22-04-2016 HRM2_RS04960 0025478858efa89ff542db6f4cce3d34 399 Gene3D G3DSA:3.90.230.10 140 397 4.0E-47 T 22-04-2016 IPR000994 Peptidase M24, structural domain HRM2_RS04960 0025478858efa89ff542db6f4cce3d34 399 PANTHER PTHR10804:SF48 27 397 5.1E-67 T 22-04-2016 HRM2_RS04960 0025478858efa89ff542db6f4cce3d34 399 Gene3D G3DSA:3.40.350.10 12 139 9.6E-17 T 22-04-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal HRM2_RS04960 0025478858efa89ff542db6f4cce3d34 399 Pfam PF00557 Metallopeptidase family M24 149 383 2.5E-33 T 22-04-2016 IPR000994 Peptidase M24, structural domain HRM2_RS07625 5a885f3894ea31ec2e846a64c276ab91 242 PANTHER PTHR24220 3 242 2.3E-146 T 22-04-2016 HRM2_RS07625 5a885f3894ea31ec2e846a64c276ab91 242 PIRSF PIRSF039085 1 241 6.9E-109 T 22-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 HRM2_RS07625 5a885f3894ea31ec2e846a64c276ab91 242 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS07625 5a885f3894ea31ec2e846a64c276ab91 242 SUPERFAMILY SSF52540 1 234 1.01E-80 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07625 5a885f3894ea31ec2e846a64c276ab91 242 PANTHER PTHR24220:SF474 3 242 2.3E-146 T 22-04-2016 HRM2_RS07625 5a885f3894ea31ec2e846a64c276ab91 242 Gene3D G3DSA:3.40.50.300 1 237 1.4E-79 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07625 5a885f3894ea31ec2e846a64c276ab91 242 SMART SM00382 26 213 1.9E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS07625 5a885f3894ea31ec2e846a64c276ab91 242 Pfam PF00005 ABC transporter 17 165 4.0E-35 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS00555 28003676bb43cbbdc0d0d187f05bc6e5 213 Pfam PF01794 Ferric reductase like transmembrane component 45 167 1.7E-12 T 22-04-2016 IPR013130 Ferric reductase transmembrane component-like domain HRM2_RS06500 da8acff3eaf166436f3d91db4a5e5e62 1400 Pfam PF13620 Carboxypeptidase regulatory-like domain 569 638 2.8E-9 T 22-04-2016 HRM2_RS06500 da8acff3eaf166436f3d91db4a5e5e62 1400 Gene3D G3DSA:2.60.40.10 565 629 8.0E-8 T 22-04-2016 IPR013783 Immunoglobulin-like fold HRM2_RS06500 da8acff3eaf166436f3d91db4a5e5e62 1400 SUPERFAMILY SSF49452 563 639 5.3E-8 T 22-04-2016 IPR013784 Carbohydrate-binding-like fold GO:0030246 HRM2_RS13870 795117b5ba3b613d4dda7e0eae506524 320 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 49 320 57.923 T 22-04-2016 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 HRM2_RS13870 795117b5ba3b613d4dda7e0eae506524 320 PANTHER PTHR11564 15 319 2.7E-122 T 22-04-2016 HRM2_RS13870 795117b5ba3b613d4dda7e0eae506524 320 SUPERFAMILY SSF47364 20 97 6.02E-16 T 22-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 HRM2_RS13870 795117b5ba3b613d4dda7e0eae506524 320 SUPERFAMILY SSF52540 118 319 1.72E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13870 795117b5ba3b613d4dda7e0eae506524 320 PANTHER PTHR11564:SF16 15 319 2.7E-122 T 22-04-2016 HRM2_RS13870 795117b5ba3b613d4dda7e0eae506524 320 Gene3D G3DSA:1.20.120.140 12 100 5.0E-21 T 22-04-2016 HRM2_RS13870 795117b5ba3b613d4dda7e0eae506524 320 SMART SM00382 118 298 1.4E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS13870 795117b5ba3b613d4dda7e0eae506524 320 Gene3D G3DSA:3.40.50.300 118 319 1.5E-76 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13870 795117b5ba3b613d4dda7e0eae506524 320 SMART SM00963 25 104 3.4E-14 T 22-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 HRM2_RS13870 795117b5ba3b613d4dda7e0eae506524 320 SMART SM00962 119 320 3.2E-113 T 22-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 HRM2_RS13870 795117b5ba3b613d4dda7e0eae506524 320 Pfam PF00448 SRP54-type protein, GTPase domain 119 319 9.8E-77 T 22-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 HRM2_RS13870 795117b5ba3b613d4dda7e0eae506524 320 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 293 306 - T 22-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 HRM2_RS13870 795117b5ba3b613d4dda7e0eae506524 320 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 51 319 1.5E-102 T 22-04-2016 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 HRM2_RS13870 795117b5ba3b613d4dda7e0eae506524 320 Pfam PF02881 SRP54-type protein, helical bundle domain 37 99 3.5E-10 T 22-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 HRM2_RS00220 123c94ea4b6ddd6f0b68d7b4d1abc57b 447 SUPERFAMILY SSF56954 4 435 5.89E-60 T 22-04-2016 HRM2_RS00220 123c94ea4b6ddd6f0b68d7b4d1abc57b 447 Gene3D G3DSA:1.20.1600.10 39 434 5.8E-48 T 22-04-2016 HRM2_RS00220 123c94ea4b6ddd6f0b68d7b4d1abc57b 447 PANTHER PTHR30203 30 435 2.7E-29 T 22-04-2016 HRM2_RS00220 123c94ea4b6ddd6f0b68d7b4d1abc57b 447 PANTHER PTHR30203:SF1 30 435 2.7E-29 T 22-04-2016 HRM2_RS00220 123c94ea4b6ddd6f0b68d7b4d1abc57b 447 Pfam PF02321 Outer membrane efflux protein 44 206 9.9E-16 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS00220 123c94ea4b6ddd6f0b68d7b4d1abc57b 447 Pfam PF02321 Outer membrane efflux protein 244 432 4.1E-19 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1585 1811 1.3E-34 T 22-04-2016 HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 Gene3D G3DSA:3.40.50.720 1672 1813 2.8E-40 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 Gene3D G3DSA:3.40.50.720 1585 1624 2.8E-40 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 PANTHER PTHR11712 1 125 4.8E-244 T 22-04-2016 HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 Pfam PF08659 KR domain 1587 1809 5.5E-38 T 22-04-2016 IPR013968 Polyketide synthase, ketoreductase domain HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 Gene3D G3DSA:3.10.129.10 2378 2515 2.4E-43 T 22-04-2016 IPR029069 HotDog domain HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 Gene3D G3DSA:3.10.129.10 2144 2330 1.3E-25 T 22-04-2016 IPR029069 HotDog domain HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 PANTHER PTHR11712 158 953 4.8E-244 T 22-04-2016 HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 SUPERFAMILY SSF55048 708 771 3.92E-8 T 22-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 187 203 - T 22-04-2016 IPR018201 Beta-ketoacyl synthase, active site HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 SUPERFAMILY SSF52151 773 873 7.85E-57 T 22-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 SUPERFAMILY SSF52151 565 705 7.85E-57 T 22-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 282 397 1.2E-38 T 22-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 274 1.1E-63 T 22-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 Gene3D G3DSA:3.30.70.250 708 771 1.2E-7 T 22-04-2016 HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 SUPERFAMILY SSF51735 1492 1571 7.75E-7 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 Pfam PF00550 Phosphopantetheine attachment site 1141 1207 1.1E-9 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 Pfam PF00550 Phosphopantetheine attachment site 1238 1306 1.0E-10 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 SUPERFAMILY SSF47336 1233 1320 3.27E-14 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 SUPERFAMILY SSF54637 2149 2330 5.97E-23 T 22-04-2016 IPR029069 HotDog domain HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 401 500 3.1E-9 T 22-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 SUPERFAMILY SSF54637 2360 2514 8.95E-30 T 22-04-2016 IPR029069 HotDog domain HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 Pfam PF14765 Polyketide synthase dehydratase 1869 2132 9.4E-28 T 22-04-2016 IPR020807 Polyketide synthase, dehydratase domain HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 PANTHER PTHR11712:SF234 1896 2131 4.8E-244 T 22-04-2016 HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 569 882 1.2E-45 T 22-04-2016 IPR020801 Polyketide synthase, acyl transferase domain HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 Pfam PF00698 Acyl transferase domain 568 866 9.5E-30 T 22-04-2016 IPR014043 Acyl transferase HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 PANTHER PTHR11712:SF234 158 953 4.8E-244 T 22-04-2016 HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 PANTHER PTHR11712:SF234 1 125 4.8E-244 T 22-04-2016 HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 Gene3D G3DSA:3.40.47.10 1 286 6.4E-66 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 SMART SM00825 Beta-ketoacyl synthase 1 452 7.5E-93 T 22-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 SUPERFAMILY SSF53901 170 394 2.4E-70 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 SUPERFAMILY SSF53901 427 443 2.4E-70 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 SUPERFAMILY SSF53901 1 114 2.4E-70 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 PANTHER PTHR11712 1896 2131 4.8E-244 T 22-04-2016 HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 Gene3D G3DSA:1.10.1200.10 1138 1209 4.3E-15 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 Gene3D G3DSA:1.10.1200.10 1234 1307 7.7E-15 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 SUPERFAMILY SSF47336 1136 1210 1.09E-11 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 SUPERFAMILY SSF51735 1584 1623 1.6E-34 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 SUPERFAMILY SSF51735 1671 1850 1.6E-34 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 Gene3D G3DSA:3.40.47.10 287 452 2.8E-52 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 Pfam PF07977 FabA-like domain 2379 2513 1.7E-35 T 22-04-2016 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 Gene3D G3DSA:3.40.366.10 772 875 9.5E-58 T 22-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 HRM2_RS25425 3173fc14542bfb0207f46d1af8191b02 2517 Gene3D G3DSA:3.40.366.10 560 699 9.5E-58 T 22-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 HRM2_RS02085 a725a01c1d3757cdfcb80c430991ddcf 82 Pfam PF03466 LysR substrate binding domain 2 71 4.8E-6 T 22-04-2016 IPR005119 LysR, substrate-binding HRM2_RS02085 a725a01c1d3757cdfcb80c430991ddcf 82 Gene3D G3DSA:3.40.190.10 23 75 1.2E-5 T 22-04-2016 HRM2_RS02085 a725a01c1d3757cdfcb80c430991ddcf 82 SUPERFAMILY SSF53850 2 71 4.34E-7 T 22-04-2016 HRM2_RS21150 ae76929cc44409e15188524e596551ee 505 PRINTS PR00344 Bacterial sensor protein C-terminal signature 489 502 1.4E-8 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS21150 ae76929cc44409e15188524e596551ee 505 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 444 1.4E-8 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS21150 ae76929cc44409e15188524e596551ee 505 PRINTS PR00344 Bacterial sensor protein C-terminal signature 448 458 1.4E-8 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS21150 ae76929cc44409e15188524e596551ee 505 PRINTS PR00344 Bacterial sensor protein C-terminal signature 465 483 1.4E-8 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS21150 ae76929cc44409e15188524e596551ee 505 SMART SM00304 229 281 1.8E-10 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS21150 ae76929cc44409e15188524e596551ee 505 PANTHER PTHR24423:SF531 179 503 2.7E-85 T 22-04-2016 HRM2_RS21150 ae76929cc44409e15188524e596551ee 505 SMART SM00388 282 346 2.6E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS21150 ae76929cc44409e15188524e596551ee 505 SUPERFAMILY SSF55874 335 503 1.96E-33 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS21150 ae76929cc44409e15188524e596551ee 505 Gene3D G3DSA:3.30.565.10 353 504 2.3E-33 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS21150 ae76929cc44409e15188524e596551ee 505 SMART SM00387 393 505 2.5E-25 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS21150 ae76929cc44409e15188524e596551ee 505 Gene3D G3DSA:1.10.287.130 272 340 1.7E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS21150 ae76929cc44409e15188524e596551ee 505 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 393 503 8.0E-16 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS21150 ae76929cc44409e15188524e596551ee 505 Pfam PF00512 His Kinase A (phospho-acceptor) domain 284 344 5.1E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS21150 ae76929cc44409e15188524e596551ee 505 PANTHER PTHR24423 179 503 2.7E-85 T 22-04-2016 HRM2_RS21150 ae76929cc44409e15188524e596551ee 505 Pfam PF00672 HAMP domain 210 277 9.5E-16 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS21150 ae76929cc44409e15188524e596551ee 505 SUPERFAMILY SSF47384 265 347 1.61E-13 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS21150 ae76929cc44409e15188524e596551ee 505 SUPERFAMILY SSF158472 229 278 5.62E-9 T 22-04-2016 HRM2_RS07545 853e8ae2f02ff72e1f29d8451cd326b6 1004 Gene3D G3DSA:3.30.70.20 778 845 1.3E-40 T 22-04-2016 HRM2_RS07545 853e8ae2f02ff72e1f29d8451cd326b6 1004 Gene3D G3DSA:3.30.70.20 915 997 1.3E-40 T 22-04-2016 HRM2_RS07545 853e8ae2f02ff72e1f29d8451cd326b6 1004 Gene3D G3DSA:3.40.228.10 203 361 4.6E-15 T 22-04-2016 HRM2_RS07545 853e8ae2f02ff72e1f29d8451cd326b6 1004 SUPERFAMILY SSF50692 570 680 1.88E-10 T 22-04-2016 IPR009010 Aspartate decarboxylase-like domain HRM2_RS07545 853e8ae2f02ff72e1f29d8451cd326b6 1004 Pfam PF01568 Molydopterin dinucleotide binding domain 586 655 4.3E-7 T 22-04-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 HRM2_RS07545 853e8ae2f02ff72e1f29d8451cd326b6 1004 PANTHER PTHR11938 945 975 2.1E-36 T 22-04-2016 HRM2_RS07545 853e8ae2f02ff72e1f29d8451cd326b6 1004 PANTHER PTHR11938 829 893 2.1E-36 T 22-04-2016 HRM2_RS07545 853e8ae2f02ff72e1f29d8451cd326b6 1004 PANTHER PTHR11938 911 929 2.1E-36 T 22-04-2016 HRM2_RS07545 853e8ae2f02ff72e1f29d8451cd326b6 1004 PANTHER PTHR11938 778 813 2.1E-36 T 22-04-2016 HRM2_RS07545 853e8ae2f02ff72e1f29d8451cd326b6 1004 SMART SM00926 44 98 1.1E-17 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS07545 853e8ae2f02ff72e1f29d8451cd326b6 1004 Pfam PF12838 4Fe-4S dicluster domain 787 856 3.3E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS07545 853e8ae2f02ff72e1f29d8451cd326b6 1004 Pfam PF12838 4Fe-4S dicluster domain 873 959 3.9E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS07545 853e8ae2f02ff72e1f29d8451cd326b6 1004 Gene3D G3DSA:3.30.70.20 846 895 2.8E-14 T 22-04-2016 HRM2_RS07545 853e8ae2f02ff72e1f29d8451cd326b6 1004 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 46 97 5.5E-17 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS07545 853e8ae2f02ff72e1f29d8451cd326b6 1004 SUPERFAMILY SSF54862 777 997 5.23E-48 T 22-04-2016 HRM2_RS07545 853e8ae2f02ff72e1f29d8451cd326b6 1004 Gene3D G3DSA:2.20.25.90 44 102 1.2E-22 T 22-04-2016 HRM2_RS07545 853e8ae2f02ff72e1f29d8451cd326b6 1004 SUPERFAMILY SSF53706 45 512 1.2E-64 T 22-04-2016 HRM2_RS07545 853e8ae2f02ff72e1f29d8451cd326b6 1004 Gene3D G3DSA:2.40.40.20 572 664 2.6E-10 T 22-04-2016 HRM2_RS07545 853e8ae2f02ff72e1f29d8451cd326b6 1004 PANTHER PTHR11938:SF86 945 975 2.1E-36 T 22-04-2016 HRM2_RS07545 853e8ae2f02ff72e1f29d8451cd326b6 1004 PANTHER PTHR11938:SF86 829 893 2.1E-36 T 22-04-2016 HRM2_RS07545 853e8ae2f02ff72e1f29d8451cd326b6 1004 PANTHER PTHR11938:SF86 911 929 2.1E-36 T 22-04-2016 HRM2_RS07545 853e8ae2f02ff72e1f29d8451cd326b6 1004 PANTHER PTHR11938:SF86 778 813 2.1E-36 T 22-04-2016 HRM2_RS07545 853e8ae2f02ff72e1f29d8451cd326b6 1004 Gene3D G3DSA:3.40.50.740 103 202 5.1E-17 T 22-04-2016 HRM2_RS07545 853e8ae2f02ff72e1f29d8451cd326b6 1004 Gene3D G3DSA:3.40.50.740 380 485 5.1E-17 T 22-04-2016 HRM2_RS20100 52f85154ca9bea182ebffe9897365ce1 151 Gene3D G3DSA:1.20.1260.10 5 141 2.5E-30 T 22-04-2016 IPR012347 Ferritin-related HRM2_RS20100 52f85154ca9bea182ebffe9897365ce1 151 PANTHER PTHR33531:SF3 5 142 1.8E-18 T 22-04-2016 HRM2_RS20100 52f85154ca9bea182ebffe9897365ce1 151 PANTHER PTHR33531 5 142 1.8E-18 T 22-04-2016 HRM2_RS20100 52f85154ca9bea182ebffe9897365ce1 151 Pfam PF02915 Rubrerythrin 8 140 3.2E-19 T 22-04-2016 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 HRM2_RS20100 52f85154ca9bea182ebffe9897365ce1 151 SUPERFAMILY SSF47240 6 149 2.2E-30 T 22-04-2016 IPR009078 Ferritin-like superfamily HRM2_RS05885 0f3316e248bac5f3715179541b741e34 529 Gene3D G3DSA:2.40.40.20 368 526 4.0E-47 T 22-04-2016 HRM2_RS05885 0f3316e248bac5f3715179541b741e34 529 SUPERFAMILY SSF53706 1 414 8.64E-133 T 22-04-2016 HRM2_RS05885 0f3316e248bac5f3715179541b741e34 529 Pfam PF00384 Molybdopterin oxidoreductase 2 331 1.7E-66 T 22-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 HRM2_RS05885 0f3316e248bac5f3715179541b741e34 529 PANTHER PTHR11615 1 527 2.0E-148 T 22-04-2016 HRM2_RS05885 0f3316e248bac5f3715179541b741e34 529 Gene3D G3DSA:3.40.50.740 222 350 2.2E-46 T 22-04-2016 HRM2_RS05885 0f3316e248bac5f3715179541b741e34 529 Gene3D G3DSA:3.40.228.10 1 219 3.1E-71 T 22-04-2016 HRM2_RS05885 0f3316e248bac5f3715179541b741e34 529 PANTHER PTHR11615:SF162 1 527 2.0E-148 T 22-04-2016 HRM2_RS05885 0f3316e248bac5f3715179541b741e34 529 SUPERFAMILY SSF50692 370 526 4.78E-42 T 22-04-2016 IPR009010 Aspartate decarboxylase-like domain HRM2_RS05885 0f3316e248bac5f3715179541b741e34 529 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 453 480 - T 22-04-2016 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 HRM2_RS05885 0f3316e248bac5f3715179541b741e34 529 Pfam PF01568 Molydopterin dinucleotide binding domain 415 519 5.1E-28 T 22-04-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 HRM2_RS11115 11a01723302db71bfe14e0cea406cf73 350 Gene3D G3DSA:2.160.10.10 120 212 5.9E-21 T 22-04-2016 HRM2_RS11115 11a01723302db71bfe14e0cea406cf73 350 SUPERFAMILY SSF51161 39 321 2.86E-74 T 22-04-2016 IPR011004 Trimeric LpxA-like HRM2_RS11115 11a01723302db71bfe14e0cea406cf73 350 Gene3D G3DSA:2.160.10.10 213 313 3.6E-24 T 22-04-2016 HRM2_RS11115 11a01723302db71bfe14e0cea406cf73 350 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 11 335 2.1E-101 T 22-04-2016 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 UniPathway: UPA00973 HRM2_RS11115 11a01723302db71bfe14e0cea406cf73 350 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 8 332 32.85 T 22-04-2016 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 UniPathway: UPA00973 HRM2_RS11115 11a01723302db71bfe14e0cea406cf73 350 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 232 264 5.6E-6 T 22-04-2016 IPR001451 Hexapeptide repeat HRM2_RS11115 11a01723302db71bfe14e0cea406cf73 350 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 265 298 4.8E-4 T 22-04-2016 IPR001451 Hexapeptide repeat HRM2_RS11115 11a01723302db71bfe14e0cea406cf73 350 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 152 186 4.5E-6 T 22-04-2016 IPR001451 Hexapeptide repeat HRM2_RS11115 11a01723302db71bfe14e0cea406cf73 350 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 112 141 0.003 T 22-04-2016 IPR001451 Hexapeptide repeat HRM2_RS11115 11a01723302db71bfe14e0cea406cf73 350 PANTHER PTHR22572:SF117 87 302 1.1E-50 T 22-04-2016 HRM2_RS11115 11a01723302db71bfe14e0cea406cf73 350 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 26 95 1.0E-15 T 22-04-2016 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 UniPathway: UPA00973 HRM2_RS11115 11a01723302db71bfe14e0cea406cf73 350 PANTHER PTHR22572 87 302 1.1E-50 T 22-04-2016 HRM2_RS11115 11a01723302db71bfe14e0cea406cf73 350 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 274 302 - T 22-04-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 HRM2_RS12945 9b20688b41302818220a73ec3e42d785 910 Gene3D G3DSA:3.60.20.10 525 753 5.1E-58 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal HRM2_RS12945 9b20688b41302818220a73ec3e42d785 910 Gene3D G3DSA:3.60.20.10 377 454 5.1E-58 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal HRM2_RS12945 9b20688b41302818220a73ec3e42d785 910 PANTHER PTHR34218 130 713 2.6E-67 T 22-04-2016 HRM2_RS12945 9b20688b41302818220a73ec3e42d785 910 Gene3D G3DSA:1.10.439.10 133 281 9.3E-36 T 22-04-2016 IPR023343 Penicillin amidase type, domain1 GO:0016811 HRM2_RS12945 9b20688b41302818220a73ec3e42d785 910 PANTHER PTHR34218:SF2 130 713 2.6E-67 T 22-04-2016 HRM2_RS12945 9b20688b41302818220a73ec3e42d785 910 Pfam PF01804 Penicillin amidase 134 836 6.4E-101 T 22-04-2016 IPR002692 Penicillin/cephalosporin acylase GO:0016787|GO:0017000 HRM2_RS12945 9b20688b41302818220a73ec3e42d785 910 SUPERFAMILY SSF56235 134 339 4.12E-109 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal HRM2_RS12945 9b20688b41302818220a73ec3e42d785 910 SUPERFAMILY SSF56235 369 877 4.12E-109 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal HRM2_RS12945 9b20688b41302818220a73ec3e42d785 910 Gene3D G3DSA:2.30.120.10 455 500 6.0E-7 T 22-04-2016 HRM2_RS12945 9b20688b41302818220a73ec3e42d785 910 Gene3D G3DSA:1.10.287.150 289 328 7.0E-9 T 22-04-2016 HRM2_RS20845 d17e83f63e5d07a62459b9a618c51e5c 529 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 343 355 8.0E-19 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS20845 d17e83f63e5d07a62459b9a618c51e5c 529 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 20 30 8.0E-19 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS20845 d17e83f63e5d07a62459b9a618c51e5c 529 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 80 92 8.0E-19 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS20845 d17e83f63e5d07a62459b9a618c51e5c 529 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 36 48 8.0E-19 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS20845 d17e83f63e5d07a62459b9a618c51e5c 529 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 307 313 8.0E-19 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS20845 d17e83f63e5d07a62459b9a618c51e5c 529 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 7 19 8.0E-19 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS20845 d17e83f63e5d07a62459b9a618c51e5c 529 PANTHER PTHR11985 1 518 3.9E-165 T 22-04-2016 HRM2_RS20845 d17e83f63e5d07a62459b9a618c51e5c 529 PANTHER PTHR11985:SF14 1 518 3.9E-165 T 22-04-2016 HRM2_RS20845 d17e83f63e5d07a62459b9a618c51e5c 529 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 12 29 - T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS20845 d17e83f63e5d07a62459b9a618c51e5c 529 SUPERFAMILY SSF51905 7 224 1.43E-39 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS20845 d17e83f63e5d07a62459b9a618c51e5c 529 SUPERFAMILY SSF51905 328 368 1.43E-39 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS20845 d17e83f63e5d07a62459b9a618c51e5c 529 SUPERFAMILY SSF54373 236 313 2.75E-7 T 22-04-2016 HRM2_RS20845 d17e83f63e5d07a62459b9a618c51e5c 529 Gene3D G3DSA:3.50.50.60 136 210 3.6E-31 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS20845 d17e83f63e5d07a62459b9a618c51e5c 529 Gene3D G3DSA:3.50.50.60 327 376 3.6E-31 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS20845 d17e83f63e5d07a62459b9a618c51e5c 529 Gene3D G3DSA:3.50.50.60 5 98 3.6E-31 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS20845 d17e83f63e5d07a62459b9a618c51e5c 529 Gene3D G3DSA:3.30.9.10 211 312 4.8E-8 T 22-04-2016 HRM2_RS20845 d17e83f63e5d07a62459b9a618c51e5c 529 Pfam PF01266 FAD dependent oxidoreductase 9 362 2.7E-45 T 22-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 HRM2_RS04910 fa398ecb75924ee9f451495f4de81d82 211 Pfam PF01381 Helix-turn-helix 37 86 2.2E-10 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS04910 fa398ecb75924ee9f451495f4de81d82 211 SMART SM00530 36 91 6.1E-12 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS04910 fa398ecb75924ee9f451495f4de81d82 211 Pfam PF07883 Cupin domain 150 196 1.7E-12 T 22-04-2016 IPR013096 Cupin 2, conserved barrel HRM2_RS04910 fa398ecb75924ee9f451495f4de81d82 211 Gene3D G3DSA:1.10.260.40 33 136 6.7E-19 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS04910 fa398ecb75924ee9f451495f4de81d82 211 SUPERFAMILY SSF47413 32 95 1.8E-13 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS04910 fa398ecb75924ee9f451495f4de81d82 211 Gene3D G3DSA:2.60.120.10 137 210 2.6E-18 T 22-04-2016 IPR014710 RmlC-like jelly roll fold HRM2_RS04910 fa398ecb75924ee9f451495f4de81d82 211 PANTHER PTHR10245 24 210 1.6E-25 T 22-04-2016 HRM2_RS04910 fa398ecb75924ee9f451495f4de81d82 211 SUPERFAMILY SSF51182 101 209 6.76E-23 T 22-04-2016 IPR011051 RmlC-like cupin domain HRM2_RS19745 240202f015421117324dae2bde673c59 846 PRINTS PR00344 Bacterial sensor protein C-terminal signature 798 816 2.5E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS19745 240202f015421117324dae2bde673c59 846 PRINTS PR00344 Bacterial sensor protein C-terminal signature 787 797 2.5E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS19745 240202f015421117324dae2bde673c59 846 PRINTS PR00344 Bacterial sensor protein C-terminal signature 769 783 2.5E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS19745 240202f015421117324dae2bde673c59 846 PRINTS PR00344 Bacterial sensor protein C-terminal signature 822 835 2.5E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS19745 240202f015421117324dae2bde673c59 846 SUPERFAMILY SSF55781 334 487 1.32E-9 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS19745 240202f015421117324dae2bde673c59 846 SUPERFAMILY SSF53850 48 265 7.11E-44 T 22-04-2016 HRM2_RS19745 240202f015421117324dae2bde673c59 846 Gene3D G3DSA:3.30.450.20 483 600 8.7E-9 T 22-04-2016 HRM2_RS19745 240202f015421117324dae2bde673c59 846 Gene3D G3DSA:3.40.190.10 227 266 8.7E-27 T 22-04-2016 HRM2_RS19745 240202f015421117324dae2bde673c59 846 Gene3D G3DSA:3.40.190.10 45 133 8.7E-27 T 22-04-2016 HRM2_RS19745 240202f015421117324dae2bde673c59 846 SUPERFAMILY SSF55785 475 601 1.26E-7 T 22-04-2016 IPR000014 PAS domain HRM2_RS19745 240202f015421117324dae2bde673c59 846 Gene3D G3DSA:3.40.190.10 135 222 1.0E-6 T 22-04-2016 HRM2_RS19745 240202f015421117324dae2bde673c59 846 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 48 264 8.4E-35 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS19745 240202f015421117324dae2bde673c59 846 SUPERFAMILY SSF47384 612 684 2.16E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS19745 240202f015421117324dae2bde673c59 846 SMART SM00062 47 267 4.8E-21 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS19745 240202f015421117324dae2bde673c59 846 Gene3D G3DSA:3.30.450.40 309 482 9.9E-11 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS19745 240202f015421117324dae2bde673c59 846 SMART SM00065 336 484 0.0028 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS19745 240202f015421117324dae2bde673c59 846 SUPERFAMILY SSF55874 692 836 2.62E-33 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS19745 240202f015421117324dae2bde673c59 846 Gene3D G3DSA:3.30.565.10 691 837 2.5E-34 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS19745 240202f015421117324dae2bde673c59 846 SMART SM00387 729 838 4.9E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS19745 240202f015421117324dae2bde673c59 846 Pfam PF13185 GAF domain 333 475 4.1E-22 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS19745 240202f015421117324dae2bde673c59 846 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 734 837 1.6E-16 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS19745 240202f015421117324dae2bde673c59 846 Gene3D G3DSA:1.10.287.130 613 683 1.2E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS19745 240202f015421117324dae2bde673c59 846 SMART SM00388 618 687 7.5E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS19745 240202f015421117324dae2bde673c59 846 PANTHER PTHR24423 472 836 6.6E-63 T 22-04-2016 HRM2_RS19745 240202f015421117324dae2bde673c59 846 PANTHER PTHR24423 40 73 6.6E-63 T 22-04-2016 HRM2_RS19745 240202f015421117324dae2bde673c59 846 Pfam PF00512 His Kinase A (phospho-acceptor) domain 618 683 1.5E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS07890 df38f444a930c18c8f0604531b667cb6 653 Gene3D G3DSA:1.10.10.60 603 644 1.8E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS07890 df38f444a930c18c8f0604531b667cb6 653 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 144 270 2.1E-13 T 22-04-2016 IPR000014 PAS domain HRM2_RS07890 df38f444a930c18c8f0604531b667cb6 653 PANTHER PTHR32071 540 648 5.4E-119 T 22-04-2016 HRM2_RS07890 df38f444a930c18c8f0604531b667cb6 653 PANTHER PTHR32071 200 487 5.4E-119 T 22-04-2016 HRM2_RS07890 df38f444a930c18c8f0604531b667cb6 653 Gene3D G3DSA:3.30.450.20 126 278 1.8E-26 T 22-04-2016 HRM2_RS07890 df38f444a930c18c8f0604531b667cb6 653 SMART SM00382 310 457 2.9E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS07890 df38f444a930c18c8f0604531b667cb6 653 Gene3D G3DSA:1.10.8.60 463 508 7.7E-9 T 22-04-2016 HRM2_RS07890 df38f444a930c18c8f0604531b667cb6 653 Gene3D G3DSA:1.10.8.60 533 581 3.0E-18 T 22-04-2016 HRM2_RS07890 df38f444a930c18c8f0604531b667cb6 653 SUPERFAMILY SSF55785 153 265 1.93E-19 T 22-04-2016 IPR000014 PAS domain HRM2_RS07890 df38f444a930c18c8f0604531b667cb6 653 SUPERFAMILY SSF46689 597 648 1.57E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS07890 df38f444a930c18c8f0604531b667cb6 653 Pfam PF00158 Sigma-54 interaction domain 290 457 1.1E-60 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS07890 df38f444a930c18c8f0604531b667cb6 653 SUPERFAMILY SSF52540 289 474 2.3E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07890 df38f444a930c18c8f0604531b667cb6 653 SUPERFAMILY SSF52540 527 572 2.3E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07890 df38f444a930c18c8f0604531b667cb6 653 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 555 564 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS07890 df38f444a930c18c8f0604531b667cb6 653 Pfam PF08447 PAS fold 174 250 9.9E-16 T 22-04-2016 IPR013655 PAS fold-3 GO:0005515 HRM2_RS07890 df38f444a930c18c8f0604531b667cb6 653 Pfam PF02954 Bacterial regulatory protein, Fis family 610 643 1.9E-8 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS07890 df38f444a930c18c8f0604531b667cb6 653 SMART SM00091 148 215 2.7E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS07890 df38f444a930c18c8f0604531b667cb6 653 Gene3D G3DSA:3.40.50.300 286 462 2.0E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07890 df38f444a930c18c8f0604531b667cb6 653 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 314 327 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS14065 ed70d065f37695476d3d657b6e2d78ed 457 PANTHER PTHR30330:SF3 1 451 1.6E-224 T 22-04-2016 HRM2_RS14065 ed70d065f37695476d3d657b6e2d78ed 457 PRINTS PR00175 Sodium/alanine symporter signature 412 432 3.5E-51 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HRM2_RS14065 ed70d065f37695476d3d657b6e2d78ed 457 PRINTS PR00175 Sodium/alanine symporter signature 92 114 3.5E-51 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HRM2_RS14065 ed70d065f37695476d3d657b6e2d78ed 457 PRINTS PR00175 Sodium/alanine symporter signature 353 375 3.5E-51 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HRM2_RS14065 ed70d065f37695476d3d657b6e2d78ed 457 PRINTS PR00175 Sodium/alanine symporter signature 307 325 3.5E-51 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HRM2_RS14065 ed70d065f37695476d3d657b6e2d78ed 457 PRINTS PR00175 Sodium/alanine symporter signature 212 231 3.5E-51 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HRM2_RS14065 ed70d065f37695476d3d657b6e2d78ed 457 PRINTS PR00175 Sodium/alanine symporter signature 184 202 3.5E-51 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HRM2_RS14065 ed70d065f37695476d3d657b6e2d78ed 457 Pfam PF01235 Sodium:alanine symporter family 55 450 1.2E-141 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HRM2_RS14065 ed70d065f37695476d3d657b6e2d78ed 457 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 443 1.7E-155 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HRM2_RS14065 ed70d065f37695476d3d657b6e2d78ed 457 PANTHER PTHR30330 1 451 1.6E-224 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HRM2_RS14065 ed70d065f37695476d3d657b6e2d78ed 457 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 92 107 - T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HRM2_RS13470 3a2f81d82c42e35b0c6951f0ea42ce04 487 Gene3D G3DSA:2.40.50.140 31 124 9.7E-31 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS13470 3a2f81d82c42e35b0c6951f0ea42ce04 487 SMART SM00316 38 118 4.3E-7 T 22-04-2016 IPR022967 RNA-binding domain, S1 HRM2_RS13470 3a2f81d82c42e35b0c6951f0ea42ce04 487 Pfam PF10150 Ribonuclease E/G family 120 389 5.6E-101 T 22-04-2016 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 HRM2_RS13470 3a2f81d82c42e35b0c6951f0ea42ce04 487 PANTHER PTHR30001 1 476 3.0E-198 T 22-04-2016 HRM2_RS13470 3a2f81d82c42e35b0c6951f0ea42ce04 487 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 15 422 1.8E-150 T 22-04-2016 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 HRM2_RS13470 3a2f81d82c42e35b0c6951f0ea42ce04 487 PANTHER PTHR30001:SF1 1 476 3.0E-198 T 22-04-2016 HRM2_RS13470 3a2f81d82c42e35b0c6951f0ea42ce04 487 SUPERFAMILY SSF50249 40 124 5.89E-17 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS13470 3a2f81d82c42e35b0c6951f0ea42ce04 487 Pfam PF00575 S1 RNA binding domain 37 105 2.4E-8 T 22-04-2016 IPR003029 S1 domain GO:0003676 HRM2_RS12860 cc8c929e2ef9fd2f3eb5f4f23838c489 164 Pfam PF13673 Acetyltransferase (GNAT) domain 45 148 3.7E-12 T 22-04-2016 IPR000182 GNAT domain GO:0008080 HRM2_RS12860 cc8c929e2ef9fd2f3eb5f4f23838c489 164 SUPERFAMILY SSF55729 1 154 8.47E-27 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS12860 cc8c929e2ef9fd2f3eb5f4f23838c489 164 PANTHER PTHR23091 9 147 5.0E-18 T 22-04-2016 HRM2_RS12860 cc8c929e2ef9fd2f3eb5f4f23838c489 164 PANTHER PTHR23091:SF275 9 147 5.0E-18 T 22-04-2016 HRM2_RS12860 cc8c929e2ef9fd2f3eb5f4f23838c489 164 Gene3D G3DSA:3.40.630.30 3 148 4.0E-33 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS04360 57530cd5d709b9b0d6ae26dfed64a99e 320 Pfam PF01207 Dihydrouridine synthase (Dus) 6 243 2.1E-34 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 HRM2_RS04360 57530cd5d709b9b0d6ae26dfed64a99e 320 PANTHER PTHR11082:SF32 1 313 2.0E-64 T 22-04-2016 HRM2_RS04360 57530cd5d709b9b0d6ae26dfed64a99e 320 PIRSF PIRSF006621 1 316 1.3E-47 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 HRM2_RS04360 57530cd5d709b9b0d6ae26dfed64a99e 320 SUPERFAMILY SSF51395 4 311 6.59E-42 T 22-04-2016 HRM2_RS04360 57530cd5d709b9b0d6ae26dfed64a99e 320 Gene3D G3DSA:3.20.20.70 2 237 9.5E-41 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS04360 57530cd5d709b9b0d6ae26dfed64a99e 320 PANTHER PTHR11082 1 313 2.0E-64 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 HRM2_RS25245 265bdf6a214815d4c47b4ef5b7b4d4bc 192 Pfam PF04972 BON domain 49 116 1.9E-14 T 22-04-2016 IPR007055 BON domain HRM2_RS25245 265bdf6a214815d4c47b4ef5b7b4d4bc 192 Pfam PF04972 BON domain 125 191 2.6E-16 T 22-04-2016 IPR007055 BON domain HRM2_RS25245 265bdf6a214815d4c47b4ef5b7b4d4bc 192 PANTHER PTHR34606 20 192 1.9E-23 T 22-04-2016 HRM2_RS25245 265bdf6a214815d4c47b4ef5b7b4d4bc 192 SMART SM00749 130 192 2.7 T 22-04-2016 IPR014004 Transport-associated and nodulation domain, bacteria HRM2_RS25245 265bdf6a214815d4c47b4ef5b7b4d4bc 192 SMART SM00749 54 117 2.5 T 22-04-2016 IPR014004 Transport-associated and nodulation domain, bacteria HRM2_RS23160 cd2c3e9ca31275317408f4f8e60bb0a4 461 Gene3D G3DSA:1.10.8.60 320 396 3.4E-23 T 22-04-2016 HRM2_RS23160 cd2c3e9ca31275317408f4f8e60bb0a4 461 SMART SM00382 167 314 2.6E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS23160 cd2c3e9ca31275317408f4f8e60bb0a4 461 Pfam PF00158 Sigma-54 interaction domain 148 314 3.6E-63 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS23160 cd2c3e9ca31275317408f4f8e60bb0a4 461 PANTHER PTHR32071:SF26 123 460 4.3E-141 T 22-04-2016 HRM2_RS23160 cd2c3e9ca31275317408f4f8e60bb0a4 461 SUPERFAMILY SSF46689 361 449 8.36E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS23160 cd2c3e9ca31275317408f4f8e60bb0a4 461 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 22 135 7.0E-11 T 22-04-2016 IPR000014 PAS domain HRM2_RS23160 cd2c3e9ca31275317408f4f8e60bb0a4 461 Pfam PF08448 PAS fold 23 129 2.8E-12 T 22-04-2016 IPR013656 PAS fold-4 HRM2_RS23160 cd2c3e9ca31275317408f4f8e60bb0a4 461 PANTHER PTHR32071 123 460 4.3E-141 T 22-04-2016 HRM2_RS23160 cd2c3e9ca31275317408f4f8e60bb0a4 461 Gene3D G3DSA:3.30.450.20 21 136 7.9E-20 T 22-04-2016 HRM2_RS23160 cd2c3e9ca31275317408f4f8e60bb0a4 461 Gene3D G3DSA:1.10.10.60 402 446 4.9E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS23160 cd2c3e9ca31275317408f4f8e60bb0a4 461 SUPERFAMILY SSF55785 15 126 4.54E-18 T 22-04-2016 IPR000014 PAS domain HRM2_RS23160 cd2c3e9ca31275317408f4f8e60bb0a4 461 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 360 369 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS23160 cd2c3e9ca31275317408f4f8e60bb0a4 461 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 171 184 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS23160 cd2c3e9ca31275317408f4f8e60bb0a4 461 SUPERFAMILY SSF52540 146 389 6.08E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23160 cd2c3e9ca31275317408f4f8e60bb0a4 461 Gene3D G3DSA:3.40.50.300 144 319 7.6E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23160 cd2c3e9ca31275317408f4f8e60bb0a4 461 Pfam PF02954 Bacterial regulatory protein, Fis family 407 446 9.6E-10 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS23160 cd2c3e9ca31275317408f4f8e60bb0a4 461 SMART SM00091 17 82 3.0E-8 T 22-04-2016 IPR000014 PAS domain HRM2_RS23160 cd2c3e9ca31275317408f4f8e60bb0a4 461 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 413 430 1.3E-7 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS23160 cd2c3e9ca31275317408f4f8e60bb0a4 461 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 430 450 1.3E-7 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS04285 af6ead22c8a6a0acf9a348139f4f21ef 431 Gene3D G3DSA:3.40.50.1980 163 272 3.2E-16 T 22-04-2016 HRM2_RS04285 af6ead22c8a6a0acf9a348139f4f21ef 431 PANTHER PTHR33712 6 427 2.1E-67 T 22-04-2016 HRM2_RS04285 af6ead22c8a6a0acf9a348139f4f21ef 431 SUPERFAMILY SSF53807 13 427 3.14E-66 T 22-04-2016 HRM2_RS04285 af6ead22c8a6a0acf9a348139f4f21ef 431 Gene3D G3DSA:3.40.50.1980 13 162 1.0E-21 T 22-04-2016 HRM2_RS04285 af6ead22c8a6a0acf9a348139f4f21ef 431 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 13 427 7.4E-51 T 22-04-2016 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 HRM2_RS15665 7ad77c4715989f7abd03e70a187899ab 379 SMART SM00359 284 367 5.2E-10 T 22-04-2016 IPR002478 PUA domain GO:0003723 HRM2_RS15665 7ad77c4715989f7abd03e70a187899ab 379 SUPERFAMILY SSF53633 13 264 1.44E-66 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HRM2_RS15665 7ad77c4715989f7abd03e70a187899ab 379 PRINTS PR00474 Glutamate 5-kinase family signature 123 144 2.6E-52 T 22-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 HRM2_RS15665 7ad77c4715989f7abd03e70a187899ab 379 PRINTS PR00474 Glutamate 5-kinase family signature 155 182 2.6E-52 T 22-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 HRM2_RS15665 7ad77c4715989f7abd03e70a187899ab 379 PRINTS PR00474 Glutamate 5-kinase family signature 49 63 2.6E-52 T 22-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 HRM2_RS15665 7ad77c4715989f7abd03e70a187899ab 379 PRINTS PR00474 Glutamate 5-kinase family signature 216 236 2.6E-52 T 22-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 HRM2_RS15665 7ad77c4715989f7abd03e70a187899ab 379 PRINTS PR00474 Glutamate 5-kinase family signature 83 111 2.6E-52 T 22-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 HRM2_RS15665 7ad77c4715989f7abd03e70a187899ab 379 Hamap MF_00456 Glutamate 5-kinase [proB]. 13 265 36.958 T 22-04-2016 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 HRM2_RS15665 7ad77c4715989f7abd03e70a187899ab 379 PANTHER PTHR11063 11 377 1.1E-111 T 22-04-2016 HRM2_RS15665 7ad77c4715989f7abd03e70a187899ab 379 Gene3D G3DSA:3.40.1160.10 9 268 1.6E-55 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HRM2_RS15665 7ad77c4715989f7abd03e70a187899ab 379 ProSitePatterns PS00902 Glutamate 5-kinase signature. 214 231 - T 22-04-2016 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 HRM2_RS15665 7ad77c4715989f7abd03e70a187899ab 379 PANTHER PTHR11063:SF12 11 377 1.1E-111 T 22-04-2016 HRM2_RS15665 7ad77c4715989f7abd03e70a187899ab 379 Pfam PF00696 Amino acid kinase family 13 241 1.9E-40 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HRM2_RS15665 7ad77c4715989f7abd03e70a187899ab 379 Pfam PF01472 PUA domain 284 358 2.9E-16 T 22-04-2016 IPR002478 PUA domain GO:0003723 HRM2_RS15665 7ad77c4715989f7abd03e70a187899ab 379 PIRSF PIRSF000729 8 376 2.1E-135 T 22-04-2016 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 HRM2_RS15665 7ad77c4715989f7abd03e70a187899ab 379 TIGRFAM TIGR01027 proB: glutamate 5-kinase 13 373 1.6E-130 T 22-04-2016 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 HRM2_RS15665 7ad77c4715989f7abd03e70a187899ab 379 SUPERFAMILY SSF88697 284 373 6.21E-20 T 22-04-2016 IPR015947 PUA-like domain HRM2_RS15665 7ad77c4715989f7abd03e70a187899ab 379 Gene3D G3DSA:2.30.130.10 281 372 6.8E-22 T 22-04-2016 IPR015947 PUA-like domain HRM2_RS02135 a90faaa0c356fb2dcaf02202ed4149fa 77 Pfam PF01541 GIY-YIG catalytic domain 3 69 1.6E-12 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily HRM2_RS02135 a90faaa0c356fb2dcaf02202ed4149fa 77 PANTHER PTHR34477:SF1 1 69 1.5E-27 T 22-04-2016 HRM2_RS02135 a90faaa0c356fb2dcaf02202ed4149fa 77 PANTHER PTHR34477 1 69 1.5E-27 T 22-04-2016 HRM2_RS02135 a90faaa0c356fb2dcaf02202ed4149fa 77 SUPERFAMILY SSF82771 1 70 8.89E-13 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily HRM2_RS23295 30b27fc3fb9749cbf29e69858511651d 357 SUPERFAMILY SSF52151 32 100 1.23E-17 T 22-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 HRM2_RS23295 30b27fc3fb9749cbf29e69858511651d 357 SUPERFAMILY SSF52151 155 317 1.23E-17 T 22-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 HRM2_RS23295 30b27fc3fb9749cbf29e69858511651d 357 Pfam PF01734 Patatin-like phospholipase 32 245 5.7E-6 T 22-04-2016 IPR002641 Patatin/Phospholipase A2-related GO:0006629 HRM2_RS10930 9be7c339f5212ac7acb089e8a1d65207 315 Pfam PF13534 4Fe-4S dicluster domain 205 271 7.4E-5 T 22-04-2016 HRM2_RS10930 9be7c339f5212ac7acb089e8a1d65207 315 Gene3D G3DSA:1.10.1060.10 191 280 2.0E-10 T 22-04-2016 HRM2_RS10930 9be7c339f5212ac7acb089e8a1d65207 315 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 205 216 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS10930 9be7c339f5212ac7acb089e8a1d65207 315 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 257 268 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS10930 9be7c339f5212ac7acb089e8a1d65207 315 SUPERFAMILY SSF46548 151 283 3.31E-16 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS13250 46467082e459937acaa5a559aceed7db 793 PANTHER PTHR30189 21 790 2.2E-36 T 22-04-2016 HRM2_RS13250 46467082e459937acaa5a559aceed7db 793 Gene3D G3DSA:2.60.450.10 45 150 8.8E-13 T 22-04-2016 HRM2_RS13250 46467082e459937acaa5a559aceed7db 793 Pfam PF04453 Organic solvent tolerance protein 310 712 1.6E-42 T 22-04-2016 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 HRM2_RS13250 46467082e459937acaa5a559aceed7db 793 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 25 789 16.542 T 22-04-2016 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 HRM2_RS13250 46467082e459937acaa5a559aceed7db 793 Pfam PF03968 OstA-like protein 54 183 1.4E-5 T 22-04-2016 IPR005653 Organic solvent tolerance-like, N-terminal HRM2_RS23985 32e77f05e15abc050077a653dacdde8c 425 PANTHER PTHR30548:SF1 27 425 1.8E-176 T 22-04-2016 HRM2_RS23985 32e77f05e15abc050077a653dacdde8c 425 PANTHER PTHR30548 27 425 1.8E-176 T 22-04-2016 HRM2_RS23985 32e77f05e15abc050077a653dacdde8c 425 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 77 424 3.1E-85 T 22-04-2016 IPR010327 FldB/FldC dehydratase alpha/beta subunit HRM2_RS19935 2a96a597a5a29f1c00c7510bac2c2304 249 Pfam PF14236 Domain of unknown function (DUF4338) 35 230 7.6E-58 T 22-04-2016 IPR025639 Domain of unknown function DUF4338 HRM2_RS13840 6c3abc23fdcead1700641ea6c41dd766 580 SMART SM01086 323 417 3.3E-9 T 22-04-2016 IPR019489 Clp ATPase, C-terminal HRM2_RS13840 6c3abc23fdcead1700641ea6c41dd766 580 SUPERFAMILY SSF52540 58 408 7.57E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13840 6c3abc23fdcead1700641ea6c41dd766 580 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 323 387 3.0E-8 T 22-04-2016 IPR019489 Clp ATPase, C-terminal HRM2_RS13840 6c3abc23fdcead1700641ea6c41dd766 580 PANTHER PTHR11262 62 228 4.6E-99 T 22-04-2016 HRM2_RS13840 6c3abc23fdcead1700641ea6c41dd766 580 PANTHER PTHR11262 244 429 4.6E-99 T 22-04-2016 HRM2_RS13840 6c3abc23fdcead1700641ea6c41dd766 580 Pfam PF07724 AAA domain (Cdc48 subfamily) 113 317 1.9E-36 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HRM2_RS13840 6c3abc23fdcead1700641ea6c41dd766 580 Gene3D G3DSA:3.40.50.300 62 263 4.0E-37 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13840 6c3abc23fdcead1700641ea6c41dd766 580 Gene3D G3DSA:3.40.50.300 300 316 4.0E-37 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13840 6c3abc23fdcead1700641ea6c41dd766 580 Gene3D G3DSA:1.10.8.60 323 414 2.3E-19 T 22-04-2016 HRM2_RS13840 6c3abc23fdcead1700641ea6c41dd766 580 SMART SM00382 112 283 3.5E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS04905 713bbc13b37776694c474cf3b5f19269 649 Pfam PF00501 AMP-binding enzyme 95 523 3.7E-48 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS04905 713bbc13b37776694c474cf3b5f19269 649 Gene3D G3DSA:3.30.300.30 524 627 3.8E-14 T 22-04-2016 HRM2_RS04905 713bbc13b37776694c474cf3b5f19269 649 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 36 92 6.5E-12 T 22-04-2016 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 HRM2_RS04905 713bbc13b37776694c474cf3b5f19269 649 SUPERFAMILY SSF56801 20 639 7.85E-129 T 22-04-2016 HRM2_RS04905 713bbc13b37776694c474cf3b5f19269 649 Gene3D G3DSA:3.40.50.980 273 419 4.5E-16 T 22-04-2016 HRM2_RS04905 713bbc13b37776694c474cf3b5f19269 649 Gene3D G3DSA:3.40.50.980 91 272 3.5E-31 T 22-04-2016 HRM2_RS04905 713bbc13b37776694c474cf3b5f19269 649 PANTHER PTHR24095:SF46 1 646 1.4E-304 T 22-04-2016 HRM2_RS04905 713bbc13b37776694c474cf3b5f19269 649 ProSitePatterns PS00455 Putative AMP-binding domain signature. 267 278 - T 22-04-2016 IPR020845 AMP-binding, conserved site HRM2_RS04905 713bbc13b37776694c474cf3b5f19269 649 PANTHER PTHR24095 1 646 1.4E-304 T 22-04-2016 HRM2_RS04905 713bbc13b37776694c474cf3b5f19269 649 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 4 649 7.3E-279 T 22-04-2016 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16 HRM2_RS07725 00468525b986c3dfadc254a758e3a6ff 508 Gene3D G3DSA:3.30.70.100 408 491 1.1E-31 T 22-04-2016 HRM2_RS07725 00468525b986c3dfadc254a758e3a6ff 508 SUPERFAMILY SSF82689 408 503 1.7E-33 T 22-04-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 HRM2_RS07725 00468525b986c3dfadc254a758e3a6ff 508 SUPERFAMILY SSF82861 252 337 2.09E-8 T 22-04-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 HRM2_RS07725 00468525b986c3dfadc254a758e3a6ff 508 Pfam PF00924 Mechanosensitive ion channel 301 493 1.9E-51 T 22-04-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 HRM2_RS07725 00468525b986c3dfadc254a758e3a6ff 508 PANTHER PTHR30221:SF7 252 507 4.3E-72 T 22-04-2016 HRM2_RS07725 00468525b986c3dfadc254a758e3a6ff 508 SUPERFAMILY SSF50182 339 404 3.92E-17 T 22-04-2016 IPR010920 LSM domain HRM2_RS07725 00468525b986c3dfadc254a758e3a6ff 508 Gene3D G3DSA:2.30.30.60 354 403 1.1E-16 T 22-04-2016 HRM2_RS07725 00468525b986c3dfadc254a758e3a6ff 508 PANTHER PTHR30221 252 507 4.3E-72 T 22-04-2016 HRM2_RS14740 f0fc74412c8d54a446ddf95dcdc8ac1d 311 PANTHER PTHR22916 11 225 7.0E-30 T 22-04-2016 HRM2_RS14740 f0fc74412c8d54a446ddf95dcdc8ac1d 311 Gene3D G3DSA:3.90.550.10 12 242 2.5E-37 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS14740 f0fc74412c8d54a446ddf95dcdc8ac1d 311 Pfam PF00535 Glycosyl transferase family 2 16 115 6.9E-25 T 22-04-2016 IPR001173 Glycosyltransferase 2-like HRM2_RS14740 f0fc74412c8d54a446ddf95dcdc8ac1d 311 SUPERFAMILY SSF53448 10 254 2.25E-37 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS14740 f0fc74412c8d54a446ddf95dcdc8ac1d 311 PANTHER PTHR22916:SF29 11 225 7.0E-30 T 22-04-2016 HRM2_RS03205 93d44d718aa4814a1fa8362bbc2de53d 147 PANTHER PTHR30353:SF12 1 141 1.6E-47 T 22-04-2016 HRM2_RS03205 93d44d718aa4814a1fa8362bbc2de53d 147 PANTHER PTHR30353 1 141 1.6E-47 T 22-04-2016 IPR032818 DedA family HRM2_RS03205 93d44d718aa4814a1fa8362bbc2de53d 147 ProDom PD085709 MEMBRANE RP436 UNCHARACTERIZED INTEGRAL PREDICTED TRANSMEMBRANE 12 119 6.0E-7 T 22-04-2016 IPR020143 Uncharacterised protein family, RP436 HRM2_RS03205 93d44d718aa4814a1fa8362bbc2de53d 147 Pfam PF09335 SNARE associated Golgi protein 27 141 6.4E-13 T 22-04-2016 IPR032816 SNARE associated Golgi protein HRM2_RS18850 bdc84a38ba8ca50acf48201a6d8b9439 147 SUPERFAMILY SSF52172 3 128 2.85E-35 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS18850 bdc84a38ba8ca50acf48201a6d8b9439 147 PANTHER PTHR26402 3 143 2.3E-34 T 22-04-2016 HRM2_RS18850 bdc84a38ba8ca50acf48201a6d8b9439 147 Pfam PF00072 Response regulator receiver domain 5 115 1.2E-27 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18850 bdc84a38ba8ca50acf48201a6d8b9439 147 Gene3D G3DSA:3.40.50.2300 2 128 5.8E-35 T 22-04-2016 HRM2_RS18850 bdc84a38ba8ca50acf48201a6d8b9439 147 SMART SM00448 3 115 1.0E-33 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS07365 838eeaa56a4149b4cf7250aaa56fe7b5 485 SUPERFAMILY SSF56112 31 324 3.55E-24 T 22-04-2016 IPR011009 Protein kinase-like domain HRM2_RS07365 838eeaa56a4149b4cf7250aaa56fe7b5 485 SMART SM00220 32 316 3.4E-8 T 22-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 HRM2_RS07365 838eeaa56a4149b4cf7250aaa56fe7b5 485 Pfam PF00069 Protein kinase domain 32 264 2.2E-14 T 22-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 HRM2_RS07365 838eeaa56a4149b4cf7250aaa56fe7b5 485 Gene3D G3DSA:1.10.510.10 144 253 1.2E-20 T 22-04-2016 HRM2_RS17605 bd2ee035683cb1935d9ebcca553bce5d 140 PANTHER PTHR31964 1 140 5.1E-32 T 22-04-2016 HRM2_RS17605 bd2ee035683cb1935d9ebcca553bce5d 140 PRINTS PR01438 Universal stress protein signature 3 21 3.2E-19 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS17605 bd2ee035683cb1935d9ebcca553bce5d 140 PRINTS PR01438 Universal stress protein signature 118 140 3.2E-19 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS17605 bd2ee035683cb1935d9ebcca553bce5d 140 PRINTS PR01438 Universal stress protein signature 100 112 3.2E-19 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS17605 bd2ee035683cb1935d9ebcca553bce5d 140 Gene3D G3DSA:3.40.50.620 1 140 2.3E-37 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS17605 bd2ee035683cb1935d9ebcca553bce5d 140 Pfam PF00582 Universal stress protein family 3 140 4.3E-29 T 22-04-2016 IPR006016 UspA GO:0006950 HRM2_RS17605 bd2ee035683cb1935d9ebcca553bce5d 140 PANTHER PTHR31964:SF26 1 140 5.1E-32 T 22-04-2016 HRM2_RS17605 bd2ee035683cb1935d9ebcca553bce5d 140 SUPERFAMILY SSF52402 3 140 1.17E-36 T 22-04-2016 HRM2_RS09050 6ddd1a009ac6671dc485829ed4501196 315 Pfam PF13186 Iron-sulfur cluster-binding domain 243 308 8.5E-11 T 22-04-2016 IPR023885 4Fe4S-binding SPASM domain HRM2_RS09050 6ddd1a009ac6671dc485829ed4501196 315 SUPERFAMILY SSF102114 32 309 4.32E-36 T 22-04-2016 HRM2_RS09050 6ddd1a009ac6671dc485829ed4501196 315 Gene3D G3DSA:3.20.20.70 30 309 1.2E-38 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS09050 6ddd1a009ac6671dc485829ed4501196 315 PANTHER PTHR11228 32 309 1.4E-13 T 22-04-2016 HRM2_RS09050 6ddd1a009ac6671dc485829ed4501196 315 Pfam PF04055 Radical SAM superfamily 40 189 1.5E-16 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS03535 85890e4259fa07cda139268a9cfb47b7 217 SUPERFAMILY SSF50249 2 70 1.74E-13 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS03535 85890e4259fa07cda139268a9cfb47b7 217 PANTHER PTHR12962 104 189 1.7E-30 T 22-04-2016 HRM2_RS03535 85890e4259fa07cda139268a9cfb47b7 217 Pfam PF06961 Protein of unknown function (DUF1294) 116 170 2.4E-25 T 22-04-2016 IPR010718 Protein of unknown function DUF1294 HRM2_RS03535 85890e4259fa07cda139268a9cfb47b7 217 Gene3D G3DSA:2.40.50.140 3 70 1.0E-17 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS03535 85890e4259fa07cda139268a9cfb47b7 217 SMART SM00357 4 68 0.0016 T 22-04-2016 IPR011129 Cold shock protein GO:0003676 HRM2_RS03535 85890e4259fa07cda139268a9cfb47b7 217 Pfam PF00313 'Cold-shock' DNA-binding domain 4 67 2.7E-10 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HRM2_RS03535 85890e4259fa07cda139268a9cfb47b7 217 PANTHER PTHR12962:SF1 104 189 1.7E-30 T 22-04-2016 HRM2_RS17015 a50e2ca454a53561bc39e100d3729dd0 148 SUPERFAMILY SSF103039 1 120 2.62E-14 T 22-04-2016 IPR028976 CheC-like domain HRM2_RS17015 a50e2ca454a53561bc39e100d3729dd0 148 Gene3D G3DSA:3.40.1550.10 1 128 6.4E-13 T 22-04-2016 IPR028976 CheC-like domain HRM2_RS17015 a50e2ca454a53561bc39e100d3729dd0 148 Pfam PF13690 Chemotaxis phosphatase CheX 46 125 2.2E-14 T 22-04-2016 IPR028051 Chemotaxis phosphatase CheX-like domain KEGG: 00231+3.-.-.-|KEGG: 00563+3.-.-.-|KEGG: 00983+3.-.-.- HRM2_RS05550 6c3552f05ac0da29a752842cf120675c 203 Gene3D G3DSA:3.40.920.10 4 195 2.6E-29 T 22-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HRM2_RS05550 6c3552f05ac0da29a752842cf120675c 203 PANTHER PTHR32154:SF22 1 194 6.3E-42 T 22-04-2016 HRM2_RS05550 6c3552f05ac0da29a752842cf120675c 203 SUPERFAMILY SSF53323 3 195 3.14E-33 T 22-04-2016 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 HRM2_RS05550 6c3552f05ac0da29a752842cf120675c 203 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 192 1.8E-34 T 22-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HRM2_RS05550 6c3552f05ac0da29a752842cf120675c 203 PANTHER PTHR32154 1 194 6.3E-42 T 22-04-2016 HRM2_RS20470 126f3f5ccfad93dc487320f8016e06ee 244 SUPERFAMILY SSF52540 7 234 1.58E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20470 126f3f5ccfad93dc487320f8016e06ee 244 Gene3D G3DSA:3.40.50.300 7 234 8.7E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20470 126f3f5ccfad93dc487320f8016e06ee 244 SMART SM00382 36 224 6.4E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS20470 126f3f5ccfad93dc487320f8016e06ee 244 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS20470 126f3f5ccfad93dc487320f8016e06ee 244 PANTHER PTHR24220:SF86 9 234 2.0E-101 T 22-04-2016 HRM2_RS20470 126f3f5ccfad93dc487320f8016e06ee 244 PANTHER PTHR24220 9 234 2.0E-101 T 22-04-2016 HRM2_RS20470 126f3f5ccfad93dc487320f8016e06ee 244 Pfam PF00005 ABC transporter 27 175 2.9E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS16660 c32cb2722c0feec6cd958063e69ac4bc 603 PANTHER PTHR30038 1 601 9.7E-194 T 22-04-2016 HRM2_RS16660 c32cb2722c0feec6cd958063e69ac4bc 603 PANTHER PTHR30038:SF0 1 601 9.7E-194 T 22-04-2016 HRM2_RS16660 c32cb2722c0feec6cd958063e69ac4bc 603 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 223 601 2.4E-106 T 22-04-2016 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS16660 c32cb2722c0feec6cd958063e69ac4bc 603 SUPERFAMILY SSF48310 213 602 4.45E-91 T 22-04-2016 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS16660 c32cb2722c0feec6cd958063e69ac4bc 603 Gene3D G3DSA:3.60.9.10 3 210 2.1E-73 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS16660 c32cb2722c0feec6cd958063e69ac4bc 603 SMART SM00790 5 208 7.0E-91 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS16660 c32cb2722c0feec6cd958063e69ac4bc 603 Gene3D G3DSA:1.10.569.10 242 423 1.8E-52 T 22-04-2016 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 HRM2_RS16660 c32cb2722c0feec6cd958063e69ac4bc 603 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 7 207 4.3E-68 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS16660 c32cb2722c0feec6cd958063e69ac4bc 603 SUPERFAMILY SSF56228 3 209 1.83E-64 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS18490 f7e745280451bd5710229ee915df7f88 560 SUPERFAMILY SSF102114 161 380 6.67E-45 T 22-04-2016 HRM2_RS18490 f7e745280451bd5710229ee915df7f88 560 Pfam PF04055 Radical SAM superfamily 187 349 2.6E-22 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS18490 f7e745280451bd5710229ee915df7f88 560 SMART SM00729 182 394 5.9E-31 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS18490 f7e745280451bd5710229ee915df7f88 560 Pfam PF02310 B12 binding domain 22 132 3.8E-17 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS18490 f7e745280451bd5710229ee915df7f88 560 PANTHER PTHR11918:SF64 14 513 6.9E-83 T 22-04-2016 HRM2_RS18490 f7e745280451bd5710229ee915df7f88 560 Gene3D G3DSA:3.80.30.20 186 377 7.6E-43 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe HRM2_RS18490 f7e745280451bd5710229ee915df7f88 560 Gene3D G3DSA:1.25.40.10 437 541 2.5E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS18490 f7e745280451bd5710229ee915df7f88 560 PANTHER PTHR11918 14 513 6.9E-83 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein HRM2_RS18490 f7e745280451bd5710229ee915df7f88 560 SUPERFAMILY SSF48452 463 541 1.24E-8 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS08210 01eaed723a626df3ef0bd451e71eca5f 177 Gene3D G3DSA:3.30.565.10 9 150 1.3E-20 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS08210 01eaed723a626df3ef0bd451e71eca5f 177 SUPERFAMILY SSF55874 8 135 2.88E-23 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS08210 01eaed723a626df3ef0bd451e71eca5f 177 PRINTS PR00344 Bacterial sensor protein C-terminal signature 54 64 5.4E-7 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS08210 01eaed723a626df3ef0bd451e71eca5f 177 PRINTS PR00344 Bacterial sensor protein C-terminal signature 90 103 5.4E-7 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS08210 01eaed723a626df3ef0bd451e71eca5f 177 PRINTS PR00344 Bacterial sensor protein C-terminal signature 66 84 5.4E-7 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS08210 01eaed723a626df3ef0bd451e71eca5f 177 PRINTS PR00344 Bacterial sensor protein C-terminal signature 36 50 5.4E-7 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS08210 01eaed723a626df3ef0bd451e71eca5f 177 SMART SM00387 3 106 9.4E-8 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS08210 01eaed723a626df3ef0bd451e71eca5f 177 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 7 102 4.7E-16 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS17420 b33e9a08c118b14ac80c200837441bab 355 Gene3D G3DSA:3.40.710.10 2 339 8.0E-68 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HRM2_RS17420 b33e9a08c118b14ac80c200837441bab 355 PANTHER PTHR22935:SF10 2 351 5.7E-61 T 22-04-2016 HRM2_RS17420 b33e9a08c118b14ac80c200837441bab 355 Pfam PF00144 Beta-lactamase 3 335 7.4E-54 T 22-04-2016 IPR001466 Beta-lactamase-related HRM2_RS17420 b33e9a08c118b14ac80c200837441bab 355 PANTHER PTHR22935 2 351 5.7E-61 T 22-04-2016 HRM2_RS17420 b33e9a08c118b14ac80c200837441bab 355 SUPERFAMILY SSF56601 3 351 4.16E-66 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HRM2_RS16330 431b690b04aa8914d95c4ddba3e796e8 287 SUPERFAMILY SSF53850 7 275 2.96E-74 T 22-04-2016 HRM2_RS16330 431b690b04aa8914d95c4ddba3e796e8 287 PANTHER PTHR37167 5 287 1.7E-92 T 22-04-2016 HRM2_RS16330 431b690b04aa8914d95c4ddba3e796e8 287 Gene3D G3DSA:3.40.190.10 83 185 1.2E-8 T 22-04-2016 HRM2_RS16330 431b690b04aa8914d95c4ddba3e796e8 287 Pfam PF02621 Menaquinone biosynthesis 7 270 2.0E-80 T 22-04-2016 IPR003773 Menaquinone biosynthesis enzyme UniPathway: UPA00079 HRM2_RS16330 431b690b04aa8914d95c4ddba3e796e8 287 Hamap MF_00996 1,4-dihydroxy-6-naphtoate synthase [mqnD]. 6 276 39.314 T 22-04-2016 IPR030869 1,4-dihydroxy-6-naphtoate synthase GO:0009234|GO:0016829 UniPathway: UPA00079 HRM2_RS23975 63268d47035a89d0feb4839436bd9ce5 404 SUPERFAMILY SSF53335 218 353 2.41E-16 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS23975 63268d47035a89d0feb4839436bd9ce5 404 PANTHER PTHR10108 199 399 3.5E-51 T 22-04-2016 HRM2_RS23975 63268d47035a89d0feb4839436bd9ce5 404 Pfam PF08241 Methyltransferase domain 280 328 2.1E-9 T 22-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 HRM2_RS23975 63268d47035a89d0feb4839436bd9ce5 404 Gene3D G3DSA:3.40.50.150 232 367 1.2E-16 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS23975 63268d47035a89d0feb4839436bd9ce5 404 PANTHER PTHR10108:SF788 199 399 3.5E-51 T 22-04-2016 HRM2_RS01545 d91a10465a3cfc00b2d547acc18698f8 436 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 1 417 29.977 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HRM2_RS01545 d91a10465a3cfc00b2d547acc18698f8 436 PANTHER PTHR21256 4 423 7.5E-139 T 22-04-2016 HRM2_RS01545 d91a10465a3cfc00b2d547acc18698f8 436 PIRSF PIRSF000099 1 420 6.1E-108 T 22-04-2016 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HRM2_RS01545 d91a10465a3cfc00b2d547acc18698f8 436 Pfam PF00815 Histidinol dehydrogenase 11 417 2.4E-127 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HRM2_RS01545 d91a10465a3cfc00b2d547acc18698f8 436 Gene3D G3DSA:3.40.50.1980 16 228 6.2E-56 T 22-04-2016 HRM2_RS01545 d91a10465a3cfc00b2d547acc18698f8 436 PRINTS PR00083 Histidinol dehydrogenase signature 219 240 1.5E-57 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HRM2_RS01545 d91a10465a3cfc00b2d547acc18698f8 436 PRINTS PR00083 Histidinol dehydrogenase signature 22 46 1.5E-57 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HRM2_RS01545 d91a10465a3cfc00b2d547acc18698f8 436 PRINTS PR00083 Histidinol dehydrogenase signature 310 335 1.5E-57 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HRM2_RS01545 d91a10465a3cfc00b2d547acc18698f8 436 PRINTS PR00083 Histidinol dehydrogenase signature 188 213 1.5E-57 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HRM2_RS01545 d91a10465a3cfc00b2d547acc18698f8 436 PRINTS PR00083 Histidinol dehydrogenase signature 241 260 1.5E-57 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HRM2_RS01545 d91a10465a3cfc00b2d547acc18698f8 436 PRINTS PR00083 Histidinol dehydrogenase signature 158 184 1.5E-57 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HRM2_RS01545 d91a10465a3cfc00b2d547acc18698f8 436 PRINTS PR00083 Histidinol dehydrogenase signature 96 123 1.5E-57 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HRM2_RS01545 d91a10465a3cfc00b2d547acc18698f8 436 PRINTS PR00083 Histidinol dehydrogenase signature 351 369 1.5E-57 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HRM2_RS01545 d91a10465a3cfc00b2d547acc18698f8 436 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 22 416 5.0E-122 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HRM2_RS01545 d91a10465a3cfc00b2d547acc18698f8 436 SUPERFAMILY SSF53720 13 417 5.1E-55 T 22-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 HRM2_RS02615 08e8aca87fc678ab506c984b548c12fb 399 Pfam PF01139 tRNA-splicing ligase RtcB 27 384 7.6E-80 T 22-04-2016 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 HRM2_RS02615 08e8aca87fc678ab506c984b548c12fb 399 PANTHER PTHR11118:SF3 1 387 1.5E-121 T 22-04-2016 HRM2_RS02615 08e8aca87fc678ab506c984b548c12fb 399 SUPERFAMILY SSF103365 10 386 9.55E-99 T 22-04-2016 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 HRM2_RS02615 08e8aca87fc678ab506c984b548c12fb 399 PANTHER PTHR11118 1 387 1.5E-121 T 22-04-2016 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 HRM2_RS13590 8125f7ca93ff424cff25aa3df5dd2647 255 SUPERFAMILY SSF53850 27 254 3.37E-24 T 22-04-2016 HRM2_RS13590 8125f7ca93ff424cff25aa3df5dd2647 255 SMART SM00062 28 255 0.0067 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS13590 8125f7ca93ff424cff25aa3df5dd2647 255 Gene3D G3DSA:3.40.190.10 28 112 2.5E-12 T 22-04-2016 HRM2_RS13590 8125f7ca93ff424cff25aa3df5dd2647 255 Gene3D G3DSA:3.40.190.10 217 255 2.5E-12 T 22-04-2016 HRM2_RS13590 8125f7ca93ff424cff25aa3df5dd2647 255 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 31 254 2.4E-13 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS21280 6236afe3fcdbae3b5c9299d4eab8b2c2 154 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 17 152 3.0E-18 T 22-04-2016 IPR024747 Pyridoxamine 5'-phosphate oxidase-related HRM2_RS21280 6236afe3fcdbae3b5c9299d4eab8b2c2 154 Gene3D G3DSA:2.30.110.10 1 152 3.9E-43 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 HRM2_RS21280 6236afe3fcdbae3b5c9299d4eab8b2c2 154 SUPERFAMILY SSF50475 1 153 5.08E-45 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 HRM2_RS21280 6236afe3fcdbae3b5c9299d4eab8b2c2 154 PANTHER PTHR34071:SF1 1 151 9.4E-45 T 22-04-2016 HRM2_RS21280 6236afe3fcdbae3b5c9299d4eab8b2c2 154 PANTHER PTHR34071 1 151 9.4E-45 T 22-04-2016 HRM2_RS11755 b9af3a3663181f040fd76c252e829287 219 SUPERFAMILY SSF52540 1 219 5.32E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11755 b9af3a3663181f040fd76c252e829287 219 PANTHER PTHR24220 3 219 1.6E-86 T 22-04-2016 HRM2_RS11755 b9af3a3663181f040fd76c252e829287 219 Pfam PF00005 ABC transporter 22 168 9.8E-36 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS11755 b9af3a3663181f040fd76c252e829287 219 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS11755 b9af3a3663181f040fd76c252e829287 219 Gene3D G3DSA:3.40.50.300 1 219 1.3E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11755 b9af3a3663181f040fd76c252e829287 219 SMART SM00382 31 215 1.8E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS20690 3136ceb7649d20aa68b21f75ffdd09b9 52 PRINTS PR00163 Rubredoxin signature 2 18 2.5E-7 T 22-04-2016 IPR024935 Rubredoxin domain GO:0005506 HRM2_RS20690 3136ceb7649d20aa68b21f75ffdd09b9 52 PRINTS PR00163 Rubredoxin signature 32 48 2.5E-7 T 22-04-2016 IPR024935 Rubredoxin domain GO:0005506 HRM2_RS20690 3136ceb7649d20aa68b21f75ffdd09b9 52 SUPERFAMILY SSF57802 1 52 2.69E-20 T 22-04-2016 HRM2_RS20690 3136ceb7649d20aa68b21f75ffdd09b9 52 PIRSF PIRSF000071 1 52 1.2E-25 T 22-04-2016 IPR024922 Rubredoxin GO:0005506|GO:0009055 HRM2_RS20690 3136ceb7649d20aa68b21f75ffdd09b9 52 Pfam PF00301 Rubredoxin 3 48 7.5E-22 T 22-04-2016 IPR024935 Rubredoxin domain GO:0005506 HRM2_RS20690 3136ceb7649d20aa68b21f75ffdd09b9 52 Gene3D G3DSA:2.20.28.10 1 50 4.2E-25 T 22-04-2016 IPR004039 Rubredoxin-type fold HRM2_RS18745 97aa879332f151f9a79eb745ec3484c8 275 SUPERFAMILY SSF55447 174 273 1.57E-28 T 22-04-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal HRM2_RS18745 97aa879332f151f9a79eb745ec3484c8 275 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 168 3.4E-49 T 22-04-2016 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 HRM2_RS18745 97aa879332f151f9a79eb745ec3484c8 275 SUPERFAMILY SSF56176 4 168 1.1E-50 T 22-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 HRM2_RS18745 97aa879332f151f9a79eb745ec3484c8 275 PANTHER PTHR11908 6 272 8.4E-77 T 22-04-2016 HRM2_RS18745 97aa879332f151f9a79eb745ec3484c8 275 Gene3D G3DSA:3.30.390.50 176 273 3.8E-31 T 22-04-2016 HRM2_RS18745 97aa879332f151f9a79eb745ec3484c8 275 SMART SM01092 175 275 3.1E-28 T 22-04-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal HRM2_RS18745 97aa879332f151f9a79eb745ec3484c8 275 Gene3D G3DSA:3.30.43.10 4 52 7.0E-8 T 22-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 HRM2_RS18745 97aa879332f151f9a79eb745ec3484c8 275 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 176 273 2.8E-26 T 22-04-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal HRM2_RS18745 97aa879332f151f9a79eb745ec3484c8 275 Gene3D G3DSA:3.30.465.10 53 168 4.6E-37 T 22-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 HRM2_RS10400 fe8ffc1aa76835701bcf58d7f6ecf4f1 254 PANTHER PTHR23046:SF3 2 252 1.4E-117 T 22-04-2016 HRM2_RS10400 fe8ffc1aa76835701bcf58d7f6ecf4f1 254 PANTHER PTHR23046 2 252 1.4E-117 T 22-04-2016 HRM2_RS10400 fe8ffc1aa76835701bcf58d7f6ecf4f1 254 Gene3D G3DSA:3.40.50.7700 120 251 1.8E-23 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 HRM2_RS10400 fe8ffc1aa76835701bcf58d7f6ecf4f1 254 Pfam PF00731 AIR carboxylase 122 249 3.4E-15 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 HRM2_RS10400 fe8ffc1aa76835701bcf58d7f6ecf4f1 254 SMART SM01001 120 252 5.0E-32 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 HRM2_RS10400 fe8ffc1aa76835701bcf58d7f6ecf4f1 254 SUPERFAMILY SSF52255 121 251 1.7E-28 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 HRM2_RS06740 3d67d4eeb7ee25d56e10377decc1f441 436 Gene3D G3DSA:3.40.50.720 1 148 3.2E-46 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS06740 3d67d4eeb7ee25d56e10377decc1f441 436 SUPERFAMILY SSF55021 353 422 3.82E-12 T 22-04-2016 HRM2_RS06740 3d67d4eeb7ee25d56e10377decc1f441 436 Gene3D G3DSA:3.30.70.260 353 423 2.2E-10 T 22-04-2016 HRM2_RS06740 3d67d4eeb7ee25d56e10377decc1f441 436 Pfam PF00742 Homoserine dehydrogenase 137 314 2.3E-66 T 22-04-2016 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 HRM2_RS06740 3d67d4eeb7ee25d56e10377decc1f441 436 PANTHER PTHR21499:SF2 1 369 7.6E-132 T 22-04-2016 HRM2_RS06740 3d67d4eeb7ee25d56e10377decc1f441 436 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 129 2.4E-17 T 22-04-2016 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 HRM2_RS06740 3d67d4eeb7ee25d56e10377decc1f441 436 Gene3D G3DSA:3.30.360.10 149 298 1.6E-57 T 22-04-2016 HRM2_RS06740 3d67d4eeb7ee25d56e10377decc1f441 436 PIRSF PIRSF000098 1 434 4.7E-158 T 22-04-2016 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 HRM2_RS06740 3d67d4eeb7ee25d56e10377decc1f441 436 Pfam PF01842 ACT domain 354 417 1.6E-10 T 22-04-2016 IPR002912 ACT domain GO:0008152|GO:0016597 HRM2_RS06740 3d67d4eeb7ee25d56e10377decc1f441 436 PANTHER PTHR21499 1 369 7.6E-132 T 22-04-2016 HRM2_RS06740 3d67d4eeb7ee25d56e10377decc1f441 436 SUPERFAMILY SSF51735 1 158 1.57E-34 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS06740 3d67d4eeb7ee25d56e10377decc1f441 436 SUPERFAMILY SSF55347 137 302 3.2E-54 T 22-04-2016 HRM2_RS06740 3d67d4eeb7ee25d56e10377decc1f441 436 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 183 205 - T 22-04-2016 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 HRM2_RS01110 7c4cdc1137773ec6d5175431c60ff381 417 Gene3D G3DSA:3.40.50.150 232 413 2.5E-26 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS01110 7c4cdc1137773ec6d5175431c60ff381 417 Gene3D G3DSA:3.30.950.10 106 204 2.5E-13 T 22-04-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 HRM2_RS01110 7c4cdc1137773ec6d5175431c60ff381 417 Gene3D G3DSA:3.40.1010.10 3 105 9.2E-23 T 22-04-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 HRM2_RS01110 7c4cdc1137773ec6d5175431c60ff381 417 SUPERFAMILY SSF53335 233 379 2.01E-24 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS01110 7c4cdc1137773ec6d5175431c60ff381 417 PANTHER PTHR14741:SF34 226 406 1.0E-40 T 22-04-2016 HRM2_RS01110 7c4cdc1137773ec6d5175431c60ff381 417 PIRSF PIRSF036428 1 412 5.0E-99 T 22-04-2016 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|KEGG: 00860+2.1.1.132|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00148 HRM2_RS01110 7c4cdc1137773ec6d5175431c60ff381 417 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 238 359 1.1E-34 T 22-04-2016 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 HRM2_RS01110 7c4cdc1137773ec6d5175431c60ff381 417 SUPERFAMILY SSF53790 3 204 1.96E-34 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 HRM2_RS01110 7c4cdc1137773ec6d5175431c60ff381 417 Pfam PF13847 Methyltransferase domain 257 359 3.2E-7 T 22-04-2016 IPR025714 Methyltransferase domain HRM2_RS01110 7c4cdc1137773ec6d5175431c60ff381 417 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 181 2.0E-18 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 HRM2_RS01110 7c4cdc1137773ec6d5175431c60ff381 417 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 5 201 1.2E-52 T 22-04-2016 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 HRM2_RS01110 7c4cdc1137773ec6d5175431c60ff381 417 PANTHER PTHR14741 226 406 1.0E-40 T 22-04-2016 HRM2_RS11515 52fd9732e7eba9099fb7fc95883e01c3 243 Pfam PF10670 Domain of unknown function (DUF4198) 5 211 1.0E-51 T 22-04-2016 IPR019613 Protein of unknown function DUF4198 HRM2_RS18080 6c3273071970676bf1fb1c2f4fcc7fa5 492 Gene3D G3DSA:3.30.300.20 370 447 1.7E-31 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta HRM2_RS18080 6c3273071970676bf1fb1c2f4fcc7fa5 492 PIRSF PIRSF006485 1 452 3.9E-160 T 22-04-2016 IPR016484 GTP-binding protein EngA GO:0005525 HRM2_RS18080 6c3273071970676bf1fb1c2f4fcc7fa5 492 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 3 445 2.0E-162 T 22-04-2016 IPR016484 GTP-binding protein EngA GO:0005525 HRM2_RS18080 6c3273071970676bf1fb1c2f4fcc7fa5 492 Pfam PF01926 50S ribosome-binding GTPase 190 303 7.1E-24 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS18080 6c3273071970676bf1fb1c2f4fcc7fa5 492 Pfam PF01926 50S ribosome-binding GTPase 5 120 2.4E-25 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS18080 6c3273071970676bf1fb1c2f4fcc7fa5 492 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 365 445 1.5E-30 T 22-04-2016 IPR032859 GTPase Der, C-terminal KH-domain-like HRM2_RS18080 6c3273071970676bf1fb1c2f4fcc7fa5 492 Gene3D G3DSA:3.40.50.300 3 172 2.9E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18080 6c3273071970676bf1fb1c2f4fcc7fa5 492 Gene3D G3DSA:3.40.50.300 186 369 1.5E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18080 6c3273071970676bf1fb1c2f4fcc7fa5 492 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 186 356 7.6E-31 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HRM2_RS18080 6c3273071970676bf1fb1c2f4fcc7fa5 492 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 153 7.9E-19 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HRM2_RS18080 6c3273071970676bf1fb1c2f4fcc7fa5 492 PANTHER PTHR11649:SF5 1 445 1.9E-131 T 22-04-2016 IPR016484 GTP-binding protein EngA GO:0005525 HRM2_RS18080 6c3273071970676bf1fb1c2f4fcc7fa5 492 SUPERFAMILY SSF52540 4 167 1.41E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18080 6c3273071970676bf1fb1c2f4fcc7fa5 492 PANTHER PTHR11649 1 445 1.9E-131 T 22-04-2016 HRM2_RS18080 6c3273071970676bf1fb1c2f4fcc7fa5 492 Hamap MF_00195 GTPase Der [der]. 2 448 38.859 T 22-04-2016 IPR016484 GTP-binding protein EngA GO:0005525 HRM2_RS18080 6c3273071970676bf1fb1c2f4fcc7fa5 492 SUPERFAMILY SSF52540 139 447 3.0E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21035 bc7ab77c893cd9473da940a24de60748 518 SUPERFAMILY SSF51905 462 515 9.48E-35 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS21035 bc7ab77c893cd9473da940a24de60748 518 SUPERFAMILY SSF51905 84 269 9.48E-35 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS21035 bc7ab77c893cd9473da940a24de60748 518 Gene3D G3DSA:3.50.50.60 454 515 9.3E-34 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS21035 bc7ab77c893cd9473da940a24de60748 518 Gene3D G3DSA:3.50.50.60 83 271 9.3E-34 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS21035 bc7ab77c893cd9473da940a24de60748 518 PIRSF PIRSF038984 2 517 4.6E-185 T 22-04-2016 IPR028348 FAD dependent protein HRM2_RS21035 bc7ab77c893cd9473da940a24de60748 518 PRINTS PR00419 Adrenodoxin reductase family signature 240 254 4.3E-7 T 22-04-2016 HRM2_RS21035 bc7ab77c893cd9473da940a24de60748 518 PRINTS PR00419 Adrenodoxin reductase family signature 83 105 4.3E-7 T 22-04-2016 HRM2_RS21035 bc7ab77c893cd9473da940a24de60748 518 PANTHER PTHR10617 58 371 6.3E-136 T 22-04-2016 HRM2_RS21035 bc7ab77c893cd9473da940a24de60748 518 PANTHER PTHR10617 453 510 6.3E-136 T 22-04-2016 HRM2_RS21035 bc7ab77c893cd9473da940a24de60748 518 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 83 252 5.8E-7 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS21035 bc7ab77c893cd9473da940a24de60748 518 PANTHER PTHR10617:SF52 58 371 6.3E-136 T 22-04-2016 HRM2_RS21035 bc7ab77c893cd9473da940a24de60748 518 PANTHER PTHR10617:SF52 453 510 6.3E-136 T 22-04-2016 HRM2_RS10610 834ccc172c43f36aaae98ca676e2537d 261 Pfam PF01556 DnaJ C terminal domain 146 250 4.9E-10 T 22-04-2016 IPR002939 Chaperone DnaJ, C-terminal HRM2_RS10610 834ccc172c43f36aaae98ca676e2537d 261 PRINTS PR00625 DnaJ domain signature 7 25 2.6E-19 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS10610 834ccc172c43f36aaae98ca676e2537d 261 PRINTS PR00625 DnaJ domain signature 25 40 2.6E-19 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS10610 834ccc172c43f36aaae98ca676e2537d 261 PRINTS PR00625 DnaJ domain signature 62 81 2.6E-19 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS10610 834ccc172c43f36aaae98ca676e2537d 261 PRINTS PR00625 DnaJ domain signature 42 62 2.6E-19 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS10610 834ccc172c43f36aaae98ca676e2537d 261 SMART SM00271 4 62 1.5E-24 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS10610 834ccc172c43f36aaae98ca676e2537d 261 Gene3D G3DSA:2.60.260.20 179 248 3.4E-10 T 22-04-2016 HRM2_RS10610 834ccc172c43f36aaae98ca676e2537d 261 PANTHER PTHR24078:SF231 1 83 4.4E-32 T 22-04-2016 HRM2_RS10610 834ccc172c43f36aaae98ca676e2537d 261 PANTHER PTHR24078:SF231 112 125 4.4E-32 T 22-04-2016 HRM2_RS10610 834ccc172c43f36aaae98ca676e2537d 261 PANTHER PTHR24078:SF231 150 249 4.4E-32 T 22-04-2016 HRM2_RS10610 834ccc172c43f36aaae98ca676e2537d 261 PANTHER PTHR24078 1 83 4.4E-32 T 22-04-2016 HRM2_RS10610 834ccc172c43f36aaae98ca676e2537d 261 PANTHER PTHR24078 112 125 4.4E-32 T 22-04-2016 HRM2_RS10610 834ccc172c43f36aaae98ca676e2537d 261 PANTHER PTHR24078 150 249 4.4E-32 T 22-04-2016 HRM2_RS10610 834ccc172c43f36aaae98ca676e2537d 261 SUPERFAMILY SSF49493 182 249 4.45E-9 T 22-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 HRM2_RS10610 834ccc172c43f36aaae98ca676e2537d 261 SUPERFAMILY SSF46565 3 89 2.49E-26 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS10610 834ccc172c43f36aaae98ca676e2537d 261 Pfam PF00226 DnaJ domain 5 67 6.8E-23 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS10610 834ccc172c43f36aaae98ca676e2537d 261 Gene3D G3DSA:1.10.287.110 2 103 2.3E-25 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS18395 66a803c5cbac241d718aae8eafd326fa 338 SUPERFAMILY SSF48029 122 329 8.5E-58 T 22-04-2016 IPR011002 Flagellar motor switch protein FliG, alpha-helical HRM2_RS18395 66a803c5cbac241d718aae8eafd326fa 338 Pfam PF14842 FliG N-terminal domain 9 112 3.4E-24 T 22-04-2016 IPR028263 Flagellar motor switch protein FliG, N-terminal domain HRM2_RS18395 66a803c5cbac241d718aae8eafd326fa 338 Pfam PF01706 FliG C-terminal domain 223 328 1.3E-36 T 22-04-2016 IPR023087 Flagellar motor switch protein FliG, C-terminal HRM2_RS18395 66a803c5cbac241d718aae8eafd326fa 338 PANTHER PTHR30534 1 337 4.9E-80 T 22-04-2016 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HRM2_RS18395 66a803c5cbac241d718aae8eafd326fa 338 PIRSF PIRSF003161 5 338 3.2E-103 T 22-04-2016 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HRM2_RS18395 66a803c5cbac241d718aae8eafd326fa 338 Pfam PF14841 FliG middle domain 123 191 1.8E-23 T 22-04-2016 IPR032779 Flagellar motor switch protein FliG, middle domain HRM2_RS18395 66a803c5cbac241d718aae8eafd326fa 338 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 7 338 3.6E-86 T 22-04-2016 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HRM2_RS18395 66a803c5cbac241d718aae8eafd326fa 338 PANTHER PTHR30534:SF0 1 337 4.9E-80 T 22-04-2016 HRM2_RS18395 66a803c5cbac241d718aae8eafd326fa 338 Gene3D G3DSA:1.10.220.30 118 192 4.5E-21 T 22-04-2016 IPR011002 Flagellar motor switch protein FliG, alpha-helical HRM2_RS18395 66a803c5cbac241d718aae8eafd326fa 338 Gene3D G3DSA:1.10.220.30 12 73 4.4E-11 T 22-04-2016 IPR011002 Flagellar motor switch protein FliG, alpha-helical HRM2_RS18395 66a803c5cbac241d718aae8eafd326fa 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 230 250 1.8E-59 T 22-04-2016 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HRM2_RS18395 66a803c5cbac241d718aae8eafd326fa 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 10 26 1.8E-59 T 22-04-2016 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HRM2_RS18395 66a803c5cbac241d718aae8eafd326fa 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 199 224 1.8E-59 T 22-04-2016 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HRM2_RS18395 66a803c5cbac241d718aae8eafd326fa 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 39 65 1.8E-59 T 22-04-2016 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HRM2_RS18395 66a803c5cbac241d718aae8eafd326fa 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 276 302 1.8E-59 T 22-04-2016 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HRM2_RS18395 66a803c5cbac241d718aae8eafd326fa 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 252 272 1.8E-59 T 22-04-2016 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HRM2_RS18395 66a803c5cbac241d718aae8eafd326fa 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 119 142 1.8E-59 T 22-04-2016 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HRM2_RS18395 66a803c5cbac241d718aae8eafd326fa 338 SUPERFAMILY SSF48029 8 110 1.44E-17 T 22-04-2016 IPR011002 Flagellar motor switch protein FliG, alpha-helical HRM2_RS18395 66a803c5cbac241d718aae8eafd326fa 338 Gene3D G3DSA:1.10.220.30 199 337 1.3E-36 T 22-04-2016 IPR011002 Flagellar motor switch protein FliG, alpha-helical HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 Gene3D G3DSA:3.30.70.370 781 891 1.1E-63 T 22-04-2016 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 Gene3D G3DSA:3.30.70.370 627 674 1.1E-63 T 22-04-2016 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 Gene3D G3DSA:1.20.1060.10 505 626 6.8E-42 T 22-04-2016 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 Gene3D G3DSA:1.10.150.20 675 780 1.4E-33 T 22-04-2016 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 SMART SM00482 649 855 1.4E-108 T 22-04-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 PANTHER PTHR10133:SF27 1 890 0.0 T 22-04-2016 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 Gene3D G3DSA:1.10.150.20 178 241 3.5E-28 T 22-04-2016 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 Pfam PF00476 DNA polymerase family A 512 888 7.4E-153 T 22-04-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 Gene3D G3DSA:3.30.420.10 290 504 2.0E-78 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 168 262 1.1E-29 T 22-04-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 TIGRFAM TIGR00593 pola: DNA polymerase I 5 891 3.5E-302 T 22-04-2016 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 SUPERFAMILY SSF88723 2 166 5.05E-54 T 22-04-2016 IPR029060 PIN domain-like HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 ProSitePatterns PS00447 DNA polymerase family A signature. 717 736 - T 22-04-2016 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 PANTHER PTHR10133 1 890 0.0 T 22-04-2016 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 SUPERFAMILY SSF53098 290 481 2.38E-51 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 SMART SM00279 169 204 7.6E-14 T 22-04-2016 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 5 166 1.9E-55 T 22-04-2016 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 SMART SM00474 293 480 1.6E-31 T 22-04-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 Gene3D G3DSA:3.40.50.1010 4 177 7.6E-69 T 22-04-2016 IPR029060 PIN domain-like HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 SUPERFAMILY SSF47807 167 282 4.34E-30 T 22-04-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 Pfam PF01612 3'-5' exonuclease 294 479 2.1E-34 T 22-04-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 PRINTS PR00868 DNA-polymerase family A (pol I) signature 663 686 1.4E-74 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 PRINTS PR00868 DNA-polymerase family A (pol I) signature 717 742 1.4E-74 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 PRINTS PR00868 DNA-polymerase family A (pol I) signature 776 787 1.4E-74 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 PRINTS PR00868 DNA-polymerase family A (pol I) signature 808 824 1.4E-74 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 PRINTS PR00868 DNA-polymerase family A (pol I) signature 693 706 1.4E-74 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 PRINTS PR00868 DNA-polymerase family A (pol I) signature 838 851 1.4E-74 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 PRINTS PR00868 DNA-polymerase family A (pol I) signature 754 765 1.4E-74 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 PRINTS PR00868 DNA-polymerase family A (pol I) signature 641 656 1.4E-74 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 PRINTS PR00868 DNA-polymerase family A (pol I) signature 618 640 1.4E-74 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 SUPERFAMILY SSF56672 483 891 3.34E-152 T 22-04-2016 HRM2_RS06140 e5cee63e9ab2481a119ef387dafada63 891 SMART SM00475 1 259 1.7E-125 T 22-04-2016 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 HRM2_RS07760 ab5b7f4f1e9c3476122f014fefdc6d7a 347 Gene3D G3DSA:2.40.50.100 56 79 3.0E-9 T 22-04-2016 HRM2_RS07760 ab5b7f4f1e9c3476122f014fefdc6d7a 347 Gene3D G3DSA:2.40.50.100 206 237 3.0E-9 T 22-04-2016 HRM2_RS07760 ab5b7f4f1e9c3476122f014fefdc6d7a 347 PANTHER PTHR32347 31 324 1.0E-53 T 22-04-2016 HRM2_RS07760 ab5b7f4f1e9c3476122f014fefdc6d7a 347 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 47 320 6.3E-12 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain HRM2_RS07760 ab5b7f4f1e9c3476122f014fefdc6d7a 347 PANTHER PTHR32347:SF12 31 324 1.0E-53 T 22-04-2016 HRM2_RS07760 ab5b7f4f1e9c3476122f014fefdc6d7a 347 SUPERFAMILY SSF111369 149 327 1.11E-7 T 22-04-2016 HRM2_RS17825 d5abb8c78b6c005ed472ff355a9c7a85 122 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 6 122 28.203 T 22-04-2016 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17825 d5abb8c78b6c005ed472ff355a9c7a85 122 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 7 122 6.1E-45 T 22-04-2016 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17825 d5abb8c78b6c005ed472ff355a9c7a85 122 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 10 122 9.5E-42 T 22-04-2016 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17825 d5abb8c78b6c005ed472ff355a9c7a85 122 SUPERFAMILY SSF53137 8 120 2.4E-51 T 22-04-2016 HRM2_RS17825 d5abb8c78b6c005ed472ff355a9c7a85 122 Gene3D G3DSA:3.30.420.100 25 122 5.8E-39 T 22-04-2016 HRM2_RS17825 d5abb8c78b6c005ed472ff355a9c7a85 122 PANTHER PTHR12899 6 122 3.9E-45 T 22-04-2016 HRM2_RS13960 43f4b3a73ab3846b0effbb6e31605f1a 1165 SUPERFAMILY SSF52540 540 801 1.35E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13960 43f4b3a73ab3846b0effbb6e31605f1a 1165 SMART SM00982 1020 1120 3.8E-29 T 22-04-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 HRM2_RS13960 43f4b3a73ab3846b0effbb6e31605f1a 1165 Gene3D G3DSA:3.30.2060.10 135 208 1.0E-10 T 22-04-2016 HRM2_RS13960 43f4b3a73ab3846b0effbb6e31605f1a 1165 Gene3D G3DSA:3.40.50.300 606 803 1.7E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13960 43f4b3a73ab3846b0effbb6e31605f1a 1165 SUPERFAMILY SSF52540 384 480 7.34E-11 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13960 43f4b3a73ab3846b0effbb6e31605f1a 1165 SUPERFAMILY SSF141259 491 565 4.71E-19 T 22-04-2016 IPR003711 CarD-like/TRCF domain HRM2_RS13960 43f4b3a73ab3846b0effbb6e31605f1a 1165 Pfam PF00270 DEAD/DEAH box helicase 622 781 1.5E-17 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HRM2_RS13960 43f4b3a73ab3846b0effbb6e31605f1a 1165 PANTHER PTHR14025:SF21 400 1138 0.0 T 22-04-2016 HRM2_RS13960 43f4b3a73ab3846b0effbb6e31605f1a 1165 Gene3D G3DSA:3.40.50.300 817 973 7.9E-34 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13960 43f4b3a73ab3846b0effbb6e31605f1a 1165 Pfam PF03461 TRCF domain 1023 1113 3.8E-23 T 22-04-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 HRM2_RS13960 43f4b3a73ab3846b0effbb6e31605f1a 1165 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 30 1162 28.015 T 22-04-2016 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 HRM2_RS13960 43f4b3a73ab3846b0effbb6e31605f1a 1165 Pfam PF02559 CarD-like/TRCF domain 497 592 3.6E-24 T 22-04-2016 IPR003711 CarD-like/TRCF domain HRM2_RS13960 43f4b3a73ab3846b0effbb6e31605f1a 1165 SUPERFAMILY SSF52540 799 1007 1.58E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13960 43f4b3a73ab3846b0effbb6e31605f1a 1165 SMART SM00487 617 807 5.6E-32 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS13960 43f4b3a73ab3846b0effbb6e31605f1a 1165 PANTHER PTHR14025 400 1138 0.0 T 22-04-2016 HRM2_RS13960 43f4b3a73ab3846b0effbb6e31605f1a 1165 SUPERFAMILY SSF143517 1006 1159 2.75E-29 T 22-04-2016 HRM2_RS13960 43f4b3a73ab3846b0effbb6e31605f1a 1165 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 151 1093 0.0 T 22-04-2016 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 HRM2_RS13960 43f4b3a73ab3846b0effbb6e31605f1a 1165 SMART SM01058 496 593 2.0E-38 T 22-04-2016 IPR003711 CarD-like/TRCF domain HRM2_RS13960 43f4b3a73ab3846b0effbb6e31605f1a 1165 SMART SM00490 843 927 2.3E-15 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS13960 43f4b3a73ab3846b0effbb6e31605f1a 1165 SUPERFAMILY SSF52540 2 346 9.58E-75 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13960 43f4b3a73ab3846b0effbb6e31605f1a 1165 Pfam PF00271 Helicase conserved C-terminal domain 824 926 5.3E-16 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS01365 faeaab4781d96c2427e5765ddaecb398 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 332 347 1.9E-20 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HRM2_RS01365 faeaab4781d96c2427e5765ddaecb398 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 50 66 1.9E-20 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HRM2_RS01365 faeaab4781d96c2427e5765ddaecb398 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 28 44 1.9E-20 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HRM2_RS01365 faeaab4781d96c2427e5765ddaecb398 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 69 87 1.9E-20 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HRM2_RS01365 faeaab4781d96c2427e5765ddaecb398 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 90 100 1.9E-20 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HRM2_RS01365 faeaab4781d96c2427e5765ddaecb398 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 257 275 1.9E-20 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HRM2_RS01365 faeaab4781d96c2427e5765ddaecb398 371 Gene3D G3DSA:3.40.50.2300 26 227 1.3E-62 T 22-04-2016 HRM2_RS01365 faeaab4781d96c2427e5765ddaecb398 371 SUPERFAMILY SSF53822 26 368 9.76E-93 T 22-04-2016 IPR028082 Periplasmic binding protein-like I HRM2_RS01365 faeaab4781d96c2427e5765ddaecb398 371 PANTHER PTHR30483 6 369 2.6E-79 T 22-04-2016 HRM2_RS01365 faeaab4781d96c2427e5765ddaecb398 371 Pfam PF13458 Periplasmic binding protein 27 366 6.2E-60 T 22-04-2016 IPR028081 Leucine-binding protein domain HRM2_RS16680 0e663a78e662a98cc8e5fe8cd5d52d5c 624 Pfam PF00005 ABC transporter 379 542 1.9E-30 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS16680 0e663a78e662a98cc8e5fe8cd5d52d5c 624 Gene3D G3DSA:3.40.50.300 361 612 1.9E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16680 0e663a78e662a98cc8e5fe8cd5d52d5c 624 SUPERFAMILY SSF52540 361 613 6.73E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16680 0e663a78e662a98cc8e5fe8cd5d52d5c 624 SMART SM00382 387 591 3.6E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS16680 0e663a78e662a98cc8e5fe8cd5d52d5c 624 Pfam PF02653 Branched-chain amino acid transport system / permease component 38 306 7.8E-44 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 HRM2_RS16680 0e663a78e662a98cc8e5fe8cd5d52d5c 624 PANTHER PTHR24220 478 614 3.8E-104 T 22-04-2016 HRM2_RS16680 0e663a78e662a98cc8e5fe8cd5d52d5c 624 PANTHER PTHR24220 364 462 3.8E-104 T 22-04-2016 HRM2_RS16680 0e663a78e662a98cc8e5fe8cd5d52d5c 624 PANTHER PTHR24220:SF358 478 614 3.8E-104 T 22-04-2016 HRM2_RS16680 0e663a78e662a98cc8e5fe8cd5d52d5c 624 PANTHER PTHR24220:SF358 364 462 3.8E-104 T 22-04-2016 HRM2_RS16680 0e663a78e662a98cc8e5fe8cd5d52d5c 624 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 591 613 2.4E-8 T 22-04-2016 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal HRM2_RS19980 6ac3fa9b33eda0b0bde682cd279b59fb 137 Gene3D G3DSA:3.30.980.10 2 77 2.2E-4 T 22-04-2016 HRM2_RS19980 6ac3fa9b33eda0b0bde682cd279b59fb 137 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 90 131 3.6E-10 T 22-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 HRM2_RS19980 6ac3fa9b33eda0b0bde682cd279b59fb 137 PANTHER PTHR11777:SF19 1 133 9.6E-38 T 22-04-2016 HRM2_RS19980 6ac3fa9b33eda0b0bde682cd279b59fb 137 SUPERFAMILY SSF55186 1 133 5.23E-31 T 22-04-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 HRM2_RS19980 6ac3fa9b33eda0b0bde682cd279b59fb 137 SMART SM00863 90 132 1.0E-8 T 22-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 HRM2_RS19980 6ac3fa9b33eda0b0bde682cd279b59fb 137 PANTHER PTHR11777 1 133 9.6E-38 T 22-04-2016 HRM2_RS13610 9a228792c3b2bd3b7aace5c2906dfb2d 181 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 7 177 1.4E-52 T 22-04-2016 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|UniPathway: UPA00084 HRM2_RS13610 9a228792c3b2bd3b7aace5c2906dfb2d 181 Pfam PF01066 CDP-alcohol phosphatidyltransferase 7 72 5.6E-16 T 22-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 HRM2_RS13610 9a228792c3b2bd3b7aace5c2906dfb2d 181 PANTHER PTHR14269 3 179 2.7E-45 T 22-04-2016 HRM2_RS13610 9a228792c3b2bd3b7aace5c2906dfb2d 181 PIRSF PIRSF000847 1 180 1.5E-48 T 22-04-2016 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|UniPathway: UPA00084 HRM2_RS13610 9a228792c3b2bd3b7aace5c2906dfb2d 181 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 50 72 - T 22-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 HRM2_RS14200 174fa51e3b289332da0e4c9605d3cf21 635 Gene3D G3DSA:2.30.38.10 419 495 2.6E-10 T 22-04-2016 HRM2_RS14200 174fa51e3b289332da0e4c9605d3cf21 635 Gene3D G3DSA:3.40.50.980 55 243 3.0E-36 T 22-04-2016 HRM2_RS14200 174fa51e3b289332da0e4c9605d3cf21 635 ProSitePatterns PS00455 Putative AMP-binding domain signature. 238 249 - T 22-04-2016 IPR020845 AMP-binding, conserved site HRM2_RS14200 174fa51e3b289332da0e4c9605d3cf21 635 SUPERFAMILY SSF56801 5 603 1.83E-153 T 22-04-2016 HRM2_RS14200 174fa51e3b289332da0e4c9605d3cf21 635 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 5 59 8.7E-25 T 22-04-2016 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 HRM2_RS14200 174fa51e3b289332da0e4c9605d3cf21 635 Pfam PF13193 AMP-binding enzyme C-terminal domain 512 590 6.9E-21 T 22-04-2016 IPR025110 AMP-binding enzyme C-terminal domain HRM2_RS14200 174fa51e3b289332da0e4c9605d3cf21 635 Gene3D G3DSA:3.40.50.980 244 404 1.8E-27 T 22-04-2016 HRM2_RS14200 174fa51e3b289332da0e4c9605d3cf21 635 Gene3D G3DSA:3.30.300.30 499 604 3.5E-21 T 22-04-2016 HRM2_RS14200 174fa51e3b289332da0e4c9605d3cf21 635 Pfam PF00501 AMP-binding enzyme 74 502 3.8E-79 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS14200 174fa51e3b289332da0e4c9605d3cf21 635 PANTHER PTHR24095 5 624 0.0 T 22-04-2016 HRM2_RS14200 174fa51e3b289332da0e4c9605d3cf21 635 PANTHER PTHR24095:SF172 5 624 0.0 T 22-04-2016 HRM2_RS08415 203f7fdfaf939ac550dbf2b5d5412193 306 PANTHER PTHR12112 5 306 4.3E-137 T 22-04-2016 HRM2_RS08415 203f7fdfaf939ac550dbf2b5d5412193 306 Gene3D G3DSA:3.90.1640.10 3 184 1.3E-59 T 22-04-2016 HRM2_RS08415 203f7fdfaf939ac550dbf2b5d5412193 306 PANTHER PTHR12112:SF23 5 306 4.3E-137 T 22-04-2016 HRM2_RS08415 203f7fdfaf939ac550dbf2b5d5412193 306 Pfam PF02833 DHHA2 domain 181 304 1.6E-21 T 22-04-2016 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1 HRM2_RS08415 203f7fdfaf939ac550dbf2b5d5412193 306 SUPERFAMILY SSF64182 3 305 1.96E-74 T 22-04-2016 HRM2_RS08415 203f7fdfaf939ac550dbf2b5d5412193 306 SMART SM01131 179 305 9.8E-58 T 22-04-2016 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1 HRM2_RS08415 203f7fdfaf939ac550dbf2b5d5412193 306 Pfam PF01368 DHH family 3 143 1.0E-22 T 22-04-2016 IPR001667 DDH domain HRM2_RS05545 0c4e762b66873ef60ba4a2f3c00be702 616 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 399 541 6.9E-27 T 22-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HRM2_RS05545 0c4e762b66873ef60ba4a2f3c00be702 616 Gene3D G3DSA:3.40.50.970 4 189 1.6E-53 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS05545 0c4e762b66873ef60ba4a2f3c00be702 616 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 24 187 1.3E-9 T 22-04-2016 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 HRM2_RS05545 0c4e762b66873ef60ba4a2f3c00be702 616 Pfam PF00037 4Fe-4S binding domain 589 611 2.8E-6 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS05545 0c4e762b66873ef60ba4a2f3c00be702 616 SUPERFAMILY SSF52922 236 303 2.47E-6 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HRM2_RS05545 0c4e762b66873ef60ba4a2f3c00be702 616 SUPERFAMILY SSF52518 366 547 5.26E-33 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS05545 0c4e762b66873ef60ba4a2f3c00be702 616 SUPERFAMILY SSF54862 546 612 1.94E-11 T 22-04-2016 HRM2_RS05545 0c4e762b66873ef60ba4a2f3c00be702 616 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 596 607 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS05545 0c4e762b66873ef60ba4a2f3c00be702 616 PANTHER PTHR18968 361 611 6.4E-66 T 22-04-2016 HRM2_RS05545 0c4e762b66873ef60ba4a2f3c00be702 616 PANTHER PTHR18968:SF136 361 611 6.4E-66 T 22-04-2016 HRM2_RS05545 0c4e762b66873ef60ba4a2f3c00be702 616 Gene3D G3DSA:3.40.50.970 354 605 2.5E-32 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS05545 0c4e762b66873ef60ba4a2f3c00be702 616 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 14 611 1.2E-231 T 22-04-2016 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 HRM2_RS05545 0c4e762b66873ef60ba4a2f3c00be702 616 SUPERFAMILY SSF52518 12 245 4.77E-55 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS05545 0c4e762b66873ef60ba4a2f3c00be702 616 PIRSF PIRSF006439 1 616 3.7E-225 T 22-04-2016 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 HRM2_RS09350 625bbb7a39c4187600983c8bba856a79 161 PANTHER PTHR33602:SF1 6 139 1.1E-30 T 22-04-2016 HRM2_RS09350 625bbb7a39c4187600983c8bba856a79 161 PANTHER PTHR33602 6 139 1.1E-30 T 22-04-2016 HRM2_RS09350 625bbb7a39c4187600983c8bba856a79 161 Pfam PF02631 RecX family 29 139 1.6E-27 T 22-04-2016 IPR003783 Regulatory protein RecX GO:0006282 HRM2_RS09350 625bbb7a39c4187600983c8bba856a79 161 Gene3D G3DSA:1.10.10.10 7 52 5.7E-8 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS09350 625bbb7a39c4187600983c8bba856a79 161 Hamap MF_01114 Regulatory protein RecX [recX]. 2 151 14.445 T 22-04-2016 IPR003783 Regulatory protein RecX GO:0006282 HRM2_RS09350 625bbb7a39c4187600983c8bba856a79 161 Gene3D G3DSA:1.10.10.10 53 97 2.1E-6 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS08890 52ce3008401d54d57182e7d55c7d09d7 72 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 12 63 1.3E-18 T 22-04-2016 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter HRM2_RS10905 47090a1a55e326cefc79e50bfaf26ffc 266 Pfam PF00795 Carbon-nitrogen hydrolase 5 251 2.6E-45 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 HRM2_RS10905 47090a1a55e326cefc79e50bfaf26ffc 266 PANTHER PTHR23088 1 251 4.7E-68 T 22-04-2016 HRM2_RS10905 47090a1a55e326cefc79e50bfaf26ffc 266 Gene3D G3DSA:3.60.110.10 1 265 7.3E-68 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 HRM2_RS10905 47090a1a55e326cefc79e50bfaf26ffc 266 SUPERFAMILY SSF56317 1 251 6.02E-65 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 HRM2_RS25220 fd9a72b4b917e6e169517c9ae498ac0f 788 Pfam PF13185 GAF domain 417 552 3.2E-8 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS25220 fd9a72b4b917e6e169517c9ae498ac0f 788 SUPERFAMILY SSF55781 397 557 3.05E-12 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS25220 fd9a72b4b917e6e169517c9ae498ac0f 788 PANTHER PTHR24421:SF23 276 787 2.2E-38 T 22-04-2016 HRM2_RS25220 fd9a72b4b917e6e169517c9ae498ac0f 788 PANTHER PTHR24421 276 787 2.2E-38 T 22-04-2016 HRM2_RS25220 fd9a72b4b917e6e169517c9ae498ac0f 788 SMART SM00065 414 561 0.0045 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS25220 fd9a72b4b917e6e169517c9ae498ac0f 788 Gene3D G3DSA:3.30.450.40 388 567 7.5E-14 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS25220 fd9a72b4b917e6e169517c9ae498ac0f 788 Gene3D G3DSA:3.30.565.10 660 786 9.9E-12 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25220 fd9a72b4b917e6e169517c9ae498ac0f 788 Pfam PF07730 Histidine kinase 584 647 1.8E-6 T 22-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 HRM2_RS25220 fd9a72b4b917e6e169517c9ae498ac0f 788 Gene3D G3DSA:3.40.50.2300 266 315 5.7E-4 T 22-04-2016 HRM2_RS25220 fd9a72b4b917e6e169517c9ae498ac0f 788 SMART SM00387 687 786 8.1E-5 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25220 fd9a72b4b917e6e169517c9ae498ac0f 788 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 689 783 1.4E-6 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25220 fd9a72b4b917e6e169517c9ae498ac0f 788 SUPERFAMILY SSF55874 656 783 2.49E-17 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS20050 66fb2ae7d4c6b1c4471b8569c336ecd2 271 Pfam PF09674 Protein of unknown function (DUF2400) 22 244 3.8E-70 T 22-04-2016 IPR014127 Conserved hypothetical protein CHP02757 HRM2_RS20050 66fb2ae7d4c6b1c4471b8569c336ecd2 271 TIGRFAM TIGR02757 TIGR02757: TIGR02757 family protein 20 246 1.4E-62 T 22-04-2016 IPR014127 Conserved hypothetical protein CHP02757 HRM2_RS10700 5f2fd1ede6ed17448565a5a2e9c1485e 126 PANTHER PTHR33937:SF3 1 108 2.7E-16 T 22-04-2016 HRM2_RS10700 5f2fd1ede6ed17448565a5a2e9c1485e 126 PANTHER PTHR33937 1 108 2.7E-16 T 22-04-2016 HRM2_RS10700 5f2fd1ede6ed17448565a5a2e9c1485e 126 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 15 101 1.0E-17 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS10700 5f2fd1ede6ed17448565a5a2e9c1485e 126 Gene3D G3DSA:3.30.420.130 1 115 4.8E-27 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS10700 5f2fd1ede6ed17448565a5a2e9c1485e 126 SUPERFAMILY SSF53146 1 119 3.53E-29 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS20575 83795322437ec66199b0197b61e23648 461 SUPERFAMILY SSF52540 149 392 2.36E-70 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20575 83795322437ec66199b0197b61e23648 461 Pfam PF00158 Sigma-54 interaction domain 150 316 3.5E-68 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS20575 83795322437ec66199b0197b61e23648 461 PANTHER PTHR32071 121 454 4.4E-146 T 22-04-2016 HRM2_RS20575 83795322437ec66199b0197b61e23648 461 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 11 133 5.3E-13 T 22-04-2016 IPR000014 PAS domain HRM2_RS20575 83795322437ec66199b0197b61e23648 461 Pfam PF13426 PAS domain 22 126 3.0E-9 T 22-04-2016 IPR000014 PAS domain HRM2_RS20575 83795322437ec66199b0197b61e23648 461 SUPERFAMILY SSF46689 405 454 6.81E-8 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS20575 83795322437ec66199b0197b61e23648 461 Gene3D G3DSA:3.30.450.20 11 119 1.6E-14 T 22-04-2016 HRM2_RS20575 83795322437ec66199b0197b61e23648 461 Pfam PF02954 Bacterial regulatory protein, Fis family 417 452 3.8E-5 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS20575 83795322437ec66199b0197b61e23648 461 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 174 187 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS20575 83795322437ec66199b0197b61e23648 461 Gene3D G3DSA:3.40.50.300 148 322 2.7E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20575 83795322437ec66199b0197b61e23648 461 SMART SM00382 170 313 8.9E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS20575 83795322437ec66199b0197b61e23648 461 SUPERFAMILY SSF55785 14 119 1.54E-14 T 22-04-2016 IPR000014 PAS domain HRM2_RS20575 83795322437ec66199b0197b61e23648 461 Gene3D G3DSA:1.10.8.60 323 400 4.9E-28 T 22-04-2016 HRM2_RS20575 83795322437ec66199b0197b61e23648 461 Gene3D G3DSA:1.10.10.60 401 454 1.1E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS20575 83795322437ec66199b0197b61e23648 461 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 363 372 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS15075 ba54480c9134eddf21ea0634d3d40206 286 Gene3D G3DSA:1.25.40.10 166 274 1.8E-12 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS15075 ba54480c9134eddf21ea0634d3d40206 286 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 165 282 2.3E-33 T 22-04-2016 IPR014162 Tol-Pal system, YbgF HRM2_RS15075 ba54480c9134eddf21ea0634d3d40206 286 PANTHER PTHR26312 176 283 6.5E-15 T 22-04-2016 HRM2_RS15075 ba54480c9134eddf21ea0634d3d40206 286 PANTHER PTHR26312:SF74 176 283 6.5E-15 T 22-04-2016 HRM2_RS15075 ba54480c9134eddf21ea0634d3d40206 286 Pfam PF13525 Outer membrane lipoprotein 162 273 2.2E-12 T 22-04-2016 HRM2_RS15075 ba54480c9134eddf21ea0634d3d40206 286 SUPERFAMILY SSF48452 167 275 2.85E-13 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS08095 db6d589b83cae0ab234f0f806155ab64 242 SUPERFAMILY SSF52540 13 233 5.96E-72 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08095 db6d589b83cae0ab234f0f806155ab64 242 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS08095 db6d589b83cae0ab234f0f806155ab64 242 PANTHER PTHR24220 15 238 7.2E-111 T 22-04-2016 HRM2_RS08095 db6d589b83cae0ab234f0f806155ab64 242 SMART SM00382 42 230 6.1E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS08095 db6d589b83cae0ab234f0f806155ab64 242 Gene3D G3DSA:3.40.50.300 11 232 9.8E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08095 db6d589b83cae0ab234f0f806155ab64 242 Pfam PF00005 ABC transporter 33 181 5.3E-27 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS08095 db6d589b83cae0ab234f0f806155ab64 242 PANTHER PTHR24220:SF578 15 238 7.2E-111 T 22-04-2016 HRM2_RS11405 a2f927ec59983fe5f0ce19e1d7cec626 414 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 380 4.1E-35 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS11405 a2f927ec59983fe5f0ce19e1d7cec626 414 PANTHER PTHR10909:SF305 3 398 7.6E-111 T 22-04-2016 HRM2_RS11405 a2f927ec59983fe5f0ce19e1d7cec626 414 Gene3D G3DSA:1.20.140.10 221 386 1.9E-52 T 22-04-2016 HRM2_RS11405 a2f927ec59983fe5f0ce19e1d7cec626 414 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 126 138 - T 22-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 HRM2_RS11405 a2f927ec59983fe5f0ce19e1d7cec626 414 Gene3D G3DSA:1.10.540.10 2 121 9.5E-27 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS11405 a2f927ec59983fe5f0ce19e1d7cec626 414 Gene3D G3DSA:2.40.110.10 124 220 3.8E-28 T 22-04-2016 HRM2_RS11405 a2f927ec59983fe5f0ce19e1d7cec626 414 SUPERFAMILY SSF47203 229 386 4.67E-44 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS11405 a2f927ec59983fe5f0ce19e1d7cec626 414 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 120 1.7E-26 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS11405 a2f927ec59983fe5f0ce19e1d7cec626 414 PANTHER PTHR10909 3 398 7.6E-111 T 22-04-2016 HRM2_RS11405 a2f927ec59983fe5f0ce19e1d7cec626 414 SUPERFAMILY SSF56645 2 240 3.53E-63 T 22-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 HRM2_RS11405 a2f927ec59983fe5f0ce19e1d7cec626 414 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 219 7.6E-19 T 22-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 HRM2_RS01235 d0ce08d7cb8753f7b247c05de742d973 425 PANTHER PTHR11476 1 421 1.3E-183 T 22-04-2016 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Reactome: REACT_71 HRM2_RS01235 d0ce08d7cb8753f7b247c05de742d973 425 PANTHER PTHR11476:SF9 1 421 1.3E-183 T 22-04-2016 HRM2_RS01235 d0ce08d7cb8753f7b247c05de742d973 425 Pfam PF03129 Anticodon binding domain 327 414 1.9E-8 T 22-04-2016 IPR004154 Anticodon-binding HRM2_RS01235 d0ce08d7cb8753f7b247c05de742d973 425 SUPERFAMILY SSF52954 324 417 2.45E-16 T 22-04-2016 IPR004154 Anticodon-binding HRM2_RS01235 d0ce08d7cb8753f7b247c05de742d973 425 Pfam PF13393 Histidyl-tRNA synthetase 7 309 2.3E-46 T 22-04-2016 HRM2_RS01235 d0ce08d7cb8753f7b247c05de742d973 425 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 3 404 5.3E-139 T 22-04-2016 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21|Reactome: REACT_71 HRM2_RS01235 d0ce08d7cb8753f7b247c05de742d973 425 PIRSF PIRSF001549 1 417 2.0E-108 T 22-04-2016 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Reactome: REACT_71 HRM2_RS01235 d0ce08d7cb8753f7b247c05de742d973 425 SUPERFAMILY SSF55681 1 316 1.43E-95 T 22-04-2016 HRM2_RS01235 d0ce08d7cb8753f7b247c05de742d973 425 Gene3D G3DSA:3.30.930.10 218 316 3.7E-91 T 22-04-2016 HRM2_RS01235 d0ce08d7cb8753f7b247c05de742d973 425 Gene3D G3DSA:3.30.930.10 2 182 3.7E-91 T 22-04-2016 HRM2_RS01235 d0ce08d7cb8753f7b247c05de742d973 425 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 419 29.223 T 22-04-2016 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21|Reactome: REACT_71 HRM2_RS01235 d0ce08d7cb8753f7b247c05de742d973 425 Gene3D G3DSA:3.40.50.800 322 413 2.2E-16 T 22-04-2016 IPR004154 Anticodon-binding HRM2_RS17595 e68b978d721706e197939205b9a0468c 336 SUPERFAMILY SSF103481 43 144 1.31E-10 T 22-04-2016 HRM2_RS17595 e68b978d721706e197939205b9a0468c 336 Pfam PF00892 EamA-like transporter family 9 141 8.6E-14 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS17595 e68b978d721706e197939205b9a0468c 336 Pfam PF00892 EamA-like transporter family 156 289 9.4E-14 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS17595 e68b978d721706e197939205b9a0468c 336 PANTHER PTHR12715 1 326 1.1E-29 T 22-04-2016 HRM2_RS01510 22b89cbb8535dca02b48ec0a8bd16ef3 272 Gene3D G3DSA:3.40.109.10 85 264 4.9E-33 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 HRM2_RS01510 22b89cbb8535dca02b48ec0a8bd16ef3 272 Gene3D G3DSA:3.30.70.20 4 50 9.6E-13 T 22-04-2016 HRM2_RS01510 22b89cbb8535dca02b48ec0a8bd16ef3 272 Pfam PF12837 4Fe-4S binding domain 41 58 8.5E-6 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS01510 22b89cbb8535dca02b48ec0a8bd16ef3 272 PANTHER PTHR23026 79 271 2.5E-32 T 22-04-2016 HRM2_RS01510 22b89cbb8535dca02b48ec0a8bd16ef3 272 SUPERFAMILY SSF54862 4 69 8.65E-15 T 22-04-2016 HRM2_RS01510 22b89cbb8535dca02b48ec0a8bd16ef3 272 Gene3D G3DSA:3.30.70.20 51 84 5.2E-8 T 22-04-2016 HRM2_RS01510 22b89cbb8535dca02b48ec0a8bd16ef3 272 Pfam PF00881 Nitroreductase family 87 253 6.3E-25 T 22-04-2016 IPR029479 Nitroreductase HRM2_RS01510 22b89cbb8535dca02b48ec0a8bd16ef3 272 PANTHER PTHR23026:SF113 79 271 2.5E-32 T 22-04-2016 HRM2_RS01510 22b89cbb8535dca02b48ec0a8bd16ef3 272 SUPERFAMILY SSF55469 172 267 2.09E-33 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 HRM2_RS01510 22b89cbb8535dca02b48ec0a8bd16ef3 272 SUPERFAMILY SSF55469 88 142 2.09E-33 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 HRM2_RS01510 22b89cbb8535dca02b48ec0a8bd16ef3 272 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 43 54 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS04560 a4f5ba44c409a64b321b365c723cd2e5 309 PIRSF PIRSF039102 42 309 5.6E-87 T 22-04-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS04560 a4f5ba44c409a64b321b365c723cd2e5 309 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 307 36.473 T 22-04-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS04560 a4f5ba44c409a64b321b365c723cd2e5 309 SUPERFAMILY SSF56059 98 307 7.07E-52 T 22-04-2016 HRM2_RS04560 a4f5ba44c409a64b321b365c723cd2e5 309 Gene3D G3DSA:3.30.1490.20 108 179 3.7E-22 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HRM2_RS04560 a4f5ba44c409a64b321b365c723cd2e5 309 PANTHER PTHR23132 1 309 5.3E-80 T 22-04-2016 HRM2_RS04560 a4f5ba44c409a64b321b365c723cd2e5 309 SUPERFAMILY SSF52440 3 97 1.06E-27 T 22-04-2016 IPR016185 Pre-ATP-grasp domain HRM2_RS04560 a4f5ba44c409a64b321b365c723cd2e5 309 Pfam PF01820 D-ala D-ala ligase N-terminus 5 87 4.7E-22 T 22-04-2016 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS04560 a4f5ba44c409a64b321b365c723cd2e5 309 Gene3D G3DSA:3.40.50.20 3 85 2.1E-25 T 22-04-2016 IPR016185 Pre-ATP-grasp domain HRM2_RS04560 a4f5ba44c409a64b321b365c723cd2e5 309 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 250 277 - T 22-04-2016 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS04560 a4f5ba44c409a64b321b365c723cd2e5 309 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 65 76 - T 22-04-2016 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS04560 a4f5ba44c409a64b321b365c723cd2e5 309 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 5 306 4.4E-91 T 22-04-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS04560 a4f5ba44c409a64b321b365c723cd2e5 309 SMART SM01209 97 281 0.0083 T 22-04-2016 HRM2_RS04560 a4f5ba44c409a64b321b365c723cd2e5 309 Pfam PF07478 D-ala D-ala ligase C-terminus 107 304 1.2E-55 T 22-04-2016 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS04560 a4f5ba44c409a64b321b365c723cd2e5 309 Gene3D G3DSA:3.30.470.20 180 309 5.6E-45 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS19075 43d4c4db786a792955a370cbf36d8df8 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 218 2.4E-22 T 22-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 HRM2_RS19075 43d4c4db786a792955a370cbf36d8df8 387 Gene3D G3DSA:1.20.140.10 219 383 1.2E-61 T 22-04-2016 HRM2_RS19075 43d4c4db786a792955a370cbf36d8df8 387 Gene3D G3DSA:1.10.540.10 1 119 7.5E-34 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS19075 43d4c4db786a792955a370cbf36d8df8 387 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 125 137 - T 22-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 HRM2_RS19075 43d4c4db786a792955a370cbf36d8df8 387 SUPERFAMILY SSF47203 229 381 1.77E-49 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS19075 43d4c4db786a792955a370cbf36d8df8 387 SUPERFAMILY SSF56645 1 242 1.2E-72 T 22-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 HRM2_RS19075 43d4c4db786a792955a370cbf36d8df8 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 376 2.9E-41 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS19075 43d4c4db786a792955a370cbf36d8df8 387 PANTHER PTHR10909 1 376 2.0E-130 T 22-04-2016 HRM2_RS19075 43d4c4db786a792955a370cbf36d8df8 387 Gene3D G3DSA:2.40.110.10 123 218 4.5E-35 T 22-04-2016 HRM2_RS19075 43d4c4db786a792955a370cbf36d8df8 387 PANTHER PTHR10909:SF305 1 376 2.0E-130 T 22-04-2016 HRM2_RS19075 43d4c4db786a792955a370cbf36d8df8 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 119 3.0E-29 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS06565 212709be01ccc5498e41e8ffbae32041 339 Gene3D G3DSA:3.30.470.20 192 331 3.4E-26 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS06565 212709be01ccc5498e41e8ffbae32041 339 Pfam PF07478 D-ala D-ala ligase C-terminus 182 328 1.0E-13 T 22-04-2016 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS06565 212709be01ccc5498e41e8ffbae32041 339 SUPERFAMILY SSF56059 107 323 2.75E-21 T 22-04-2016 HRM2_RS06565 212709be01ccc5498e41e8ffbae32041 339 PANTHER PTHR23132 64 338 4.1E-27 T 22-04-2016 HRM2_RS08360 0599a5d7dda7cd7ebf5dce33b9e100e7 193 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 6 183 32.118 T 22-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 HRM2_RS08360 0599a5d7dda7cd7ebf5dce33b9e100e7 193 PANTHER PTHR17224:SF1 1 193 5.0E-67 T 22-04-2016 HRM2_RS08360 0599a5d7dda7cd7ebf5dce33b9e100e7 193 Gene3D G3DSA:3.40.50.1470 4 191 7.4E-67 T 22-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 HRM2_RS08360 0599a5d7dda7cd7ebf5dce33b9e100e7 193 SUPERFAMILY SSF53178 6 190 1.2E-60 T 22-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 HRM2_RS08360 0599a5d7dda7cd7ebf5dce33b9e100e7 193 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 112 122 - T 22-04-2016 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 HRM2_RS08360 0599a5d7dda7cd7ebf5dce33b9e100e7 193 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 8 190 1.1E-53 T 22-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 HRM2_RS08360 0599a5d7dda7cd7ebf5dce33b9e100e7 193 PANTHER PTHR17224 1 193 5.0E-67 T 22-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 HRM2_RS08360 0599a5d7dda7cd7ebf5dce33b9e100e7 193 Pfam PF01195 Peptidyl-tRNA hydrolase 8 187 8.4E-51 T 22-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 HRM2_RS08920 109990712d8c12a12a9b812b2d4116c2 201 Gene3D G3DSA:3.40.50.1390 7 129 3.3E-36 T 22-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HRM2_RS08920 109990712d8c12a12a9b812b2d4116c2 201 Pfam PF02796 Helix-turn-helix domain of resolvase 148 192 1.4E-6 T 22-04-2016 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 HRM2_RS08920 109990712d8c12a12a9b812b2d4116c2 201 PANTHER PTHR30461 9 192 7.0E-38 T 22-04-2016 HRM2_RS08920 109990712d8c12a12a9b812b2d4116c2 201 ProSitePatterns PS00397 Site-specific recombinases active site. 11 19 - T 22-04-2016 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 HRM2_RS08920 109990712d8c12a12a9b812b2d4116c2 201 Pfam PF00239 Resolvase, N terminal domain 9 145 2.5E-38 T 22-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HRM2_RS08920 109990712d8c12a12a9b812b2d4116c2 201 SUPERFAMILY SSF53041 7 145 1.7E-39 T 22-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HRM2_RS08920 109990712d8c12a12a9b812b2d4116c2 201 SMART SM00857 8 146 5.4E-47 T 22-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HRM2_RS08920 109990712d8c12a12a9b812b2d4116c2 201 Gene3D G3DSA:1.10.10.60 148 191 2.5E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS07715 6079ef826022cf026b2899644f6005c3 340 Pfam PF11449 Putative, 10TM heavy-metal exporter 12 313 3.2E-33 T 22-04-2016 IPR021552 Putative, 10TM heavy-metal exporter HRM2_RS07620 5bb02cae999c1ea411ab58e408ae107c 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 216 3.6E-21 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS07620 5bb02cae999c1ea411ab58e408ae107c 217 PANTHER PTHR30614 1 217 1.3E-74 T 22-04-2016 HRM2_RS07620 5bb02cae999c1ea411ab58e408ae107c 217 Gene3D G3DSA:1.10.3720.10 14 215 2.4E-49 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS07620 5bb02cae999c1ea411ab58e408ae107c 217 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 109 8.6E-26 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HRM2_RS07620 5bb02cae999c1ea411ab58e408ae107c 217 SUPERFAMILY SSF161098 14 207 1.09E-44 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS04130 cd296c702c9c1088465d951a4f81cca9 241 SUPERFAMILY SSF52540 1 235 2.01E-79 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04130 cd296c702c9c1088465d951a4f81cca9 241 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS04130 cd296c702c9c1088465d951a4f81cca9 241 PANTHER PTHR24220:SF474 3 240 3.1E-139 T 22-04-2016 HRM2_RS04130 cd296c702c9c1088465d951a4f81cca9 241 SMART SM00382 26 213 1.7E-17 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS04130 cd296c702c9c1088465d951a4f81cca9 241 Pfam PF00005 ABC transporter 17 165 9.8E-38 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS04130 cd296c702c9c1088465d951a4f81cca9 241 PIRSF PIRSF039085 1 241 4.6E-107 T 22-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 HRM2_RS04130 cd296c702c9c1088465d951a4f81cca9 241 PANTHER PTHR24220 3 240 3.1E-139 T 22-04-2016 HRM2_RS04130 cd296c702c9c1088465d951a4f81cca9 241 Gene3D G3DSA:3.40.50.300 1 237 2.1E-84 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06120 5cde47141c9e6e62578e8e70d3ddedce 106 ProSitePatterns PS00194 Thioredoxin family active site. 24 42 - T 22-04-2016 IPR017937 Thioredoxin, conserved site GO:0045454 HRM2_RS06120 5cde47141c9e6e62578e8e70d3ddedce 106 Pfam PF00085 Thioredoxin 4 105 8.6E-34 T 22-04-2016 IPR013766 Thioredoxin domain GO:0045454 HRM2_RS06120 5cde47141c9e6e62578e8e70d3ddedce 106 Gene3D G3DSA:3.40.30.10 2 105 8.8E-41 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS06120 5cde47141c9e6e62578e8e70d3ddedce 106 PIRSF PIRSF000077 1 106 9.2E-40 T 22-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 HRM2_RS06120 5cde47141c9e6e62578e8e70d3ddedce 106 PANTHER PTHR10438 2 106 9.1E-44 T 22-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 HRM2_RS06120 5cde47141c9e6e62578e8e70d3ddedce 106 SUPERFAMILY SSF52833 2 105 1.32E-39 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS06120 5cde47141c9e6e62578e8e70d3ddedce 106 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 104 3.7E-37 T 22-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 HRM2_RS06120 5cde47141c9e6e62578e8e70d3ddedce 106 PRINTS PR00421 Thioredoxin family signature 31 40 9.5E-10 T 22-04-2016 HRM2_RS06120 5cde47141c9e6e62578e8e70d3ddedce 106 PRINTS PR00421 Thioredoxin family signature 23 31 9.5E-10 T 22-04-2016 HRM2_RS06120 5cde47141c9e6e62578e8e70d3ddedce 106 PRINTS PR00421 Thioredoxin family signature 71 82 9.5E-10 T 22-04-2016 HRM2_RS00310 8533476366ea3c59000c4e201c3292bc 473 PANTHER PTHR11938 1 31 1.3E-110 T 22-04-2016 HRM2_RS00310 8533476366ea3c59000c4e201c3292bc 473 PANTHER PTHR11938 132 141 1.3E-110 T 22-04-2016 HRM2_RS00310 8533476366ea3c59000c4e201c3292bc 473 PANTHER PTHR11938 168 331 1.3E-110 T 22-04-2016 HRM2_RS00310 8533476366ea3c59000c4e201c3292bc 473 SUPERFAMILY SSF54862 1 452 2.72E-141 T 22-04-2016 HRM2_RS00310 8533476366ea3c59000c4e201c3292bc 473 Gene3D G3DSA:3.30.70.20 194 233 2.1E-25 T 22-04-2016 HRM2_RS00310 8533476366ea3c59000c4e201c3292bc 473 Gene3D G3DSA:3.30.70.20 234 356 1.0E-60 T 22-04-2016 HRM2_RS00310 8533476366ea3c59000c4e201c3292bc 473 Gene3D G3DSA:3.30.70.20 429 453 1.0E-60 T 22-04-2016 HRM2_RS00310 8533476366ea3c59000c4e201c3292bc 473 Gene3D G3DSA:3.30.70.20 58 59 2.7E-9 T 22-04-2016 HRM2_RS00310 8533476366ea3c59000c4e201c3292bc 473 Gene3D G3DSA:3.30.70.20 10 26 2.7E-9 T 22-04-2016 HRM2_RS00310 8533476366ea3c59000c4e201c3292bc 473 Gene3D G3DSA:3.30.70.20 172 193 2.7E-9 T 22-04-2016 HRM2_RS00310 8533476366ea3c59000c4e201c3292bc 473 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 471 9.3E-224 T 22-04-2016 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 HRM2_RS00310 8533476366ea3c59000c4e201c3292bc 473 Pfam PF13247 4Fe-4S dicluster domain 173 269 3.6E-38 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS00310 8533476366ea3c59000c4e201c3292bc 473 Gene3D G3DSA:1.10.3650.10 357 427 1.4E-21 T 22-04-2016 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 HRM2_RS00310 8533476366ea3c59000c4e201c3292bc 473 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 356 429 6.0E-22 T 22-04-2016 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 HRM2_RS00310 8533476366ea3c59000c4e201c3292bc 473 PANTHER PTHR11938:SF8 1 31 1.3E-110 T 22-04-2016 HRM2_RS00310 8533476366ea3c59000c4e201c3292bc 473 PANTHER PTHR11938:SF8 132 141 1.3E-110 T 22-04-2016 HRM2_RS00310 8533476366ea3c59000c4e201c3292bc 473 PANTHER PTHR11938:SF8 168 331 1.3E-110 T 22-04-2016 HRM2_RS15740 d29ffa64300581285255817c8e2aef84 289 SMART SM00470 32 121 3.2E-31 T 22-04-2016 IPR003115 ParB/Sulfiredoxin HRM2_RS15740 d29ffa64300581285255817c8e2aef84 289 Gene3D G3DSA:3.90.1530.10 27 127 1.9E-35 T 22-04-2016 HRM2_RS15740 d29ffa64300581285255817c8e2aef84 289 Pfam PF02195 ParB-like nuclease domain 34 121 2.5E-24 T 22-04-2016 IPR003115 ParB/Sulfiredoxin HRM2_RS15740 d29ffa64300581285255817c8e2aef84 289 SUPERFAMILY SSF110849 33 123 1.02E-27 T 22-04-2016 IPR003115 ParB/Sulfiredoxin HRM2_RS15740 d29ffa64300581285255817c8e2aef84 289 PANTHER PTHR33375 9 287 8.4E-83 T 22-04-2016 HRM2_RS15740 d29ffa64300581285255817c8e2aef84 289 PANTHER PTHR33375:SF3 9 287 8.4E-83 T 22-04-2016 HRM2_RS15740 d29ffa64300581285255817c8e2aef84 289 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 31 202 1.4E-54 T 22-04-2016 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 HRM2_RS15740 d29ffa64300581285255817c8e2aef84 289 SUPERFAMILY SSF109709 113 224 5.49E-34 T 22-04-2016 HRM2_RS10350 b0b73cb54f2e5879b27159da9511258a 305 Pfam PF00072 Response regulator receiver domain 5 113 3.1E-26 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS10350 b0b73cb54f2e5879b27159da9511258a 305 SMART SM00267 126 298 2.8E-57 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS10350 b0b73cb54f2e5879b27159da9511258a 305 PANTHER PTHR26402 3 138 1.1E-35 T 22-04-2016 HRM2_RS10350 b0b73cb54f2e5879b27159da9511258a 305 SUPERFAMILY SSF55073 142 296 4.55E-45 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS10350 b0b73cb54f2e5879b27159da9511258a 305 SMART SM00448 3 113 8.4E-32 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS10350 b0b73cb54f2e5879b27159da9511258a 305 Pfam PF00990 Diguanylate cyclase, GGDEF domain 137 294 1.3E-47 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS10350 b0b73cb54f2e5879b27159da9511258a 305 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 133 296 2.7E-52 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS10350 b0b73cb54f2e5879b27159da9511258a 305 Gene3D G3DSA:3.40.50.2300 2 134 2.5E-36 T 22-04-2016 HRM2_RS10350 b0b73cb54f2e5879b27159da9511258a 305 SUPERFAMILY SSF52172 3 135 3.84E-38 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS10350 b0b73cb54f2e5879b27159da9511258a 305 Gene3D G3DSA:3.30.70.270 139 297 1.2E-49 T 22-04-2016 HRM2_RS20230 ee23474bc57472f28f920660d58e233a 654 TIGRFAM TIGR01702 CO_DH_cata: carbon-monoxide dehydrogenase, catalytic subunit 22 637 1.5E-173 T 22-04-2016 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.99.2|KEGG: 00680+1.2.99.2|KEGG: 00720+1.2.99.2|MetaCyc: PWY-5372|MetaCyc: PWY-6780 HRM2_RS20230 ee23474bc57472f28f920660d58e233a 654 SUPERFAMILY SSF56821 11 639 4.06E-175 T 22-04-2016 IPR011254 Prismane-like GO:0003824|GO:0016491|GO:0055114 HRM2_RS20230 ee23474bc57472f28f920660d58e233a 654 PANTHER PTHR30109:SF4 17 638 5.5E-176 T 22-04-2016 HRM2_RS20230 ee23474bc57472f28f920660d58e233a 654 Gene3D G3DSA:1.20.1270.30 75 247 3.3E-64 T 22-04-2016 IPR016101 CO dehydrogenase, alpha-bundle GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.99.2|KEGG: 00680+1.2.99.2|KEGG: 00720+1.2.99.2|MetaCyc: PWY-5372|MetaCyc: PWY-6780 HRM2_RS20230 ee23474bc57472f28f920660d58e233a 654 Gene3D G3DSA:3.40.50.2030 249 413 2.5E-57 T 22-04-2016 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS20230 ee23474bc57472f28f920660d58e233a 654 Pfam PF03063 Prismane/CO dehydrogenase family 57 617 7.6E-148 T 22-04-2016 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS20230 ee23474bc57472f28f920660d58e233a 654 Gene3D G3DSA:3.40.50.2030 416 638 1.3E-77 T 22-04-2016 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS20230 ee23474bc57472f28f920660d58e233a 654 PANTHER PTHR30109 17 638 5.5E-176 T 22-04-2016 HRM2_RS20230 ee23474bc57472f28f920660d58e233a 654 PIRSF PIRSF005023 3 638 1.0E-195 T 22-04-2016 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.99.2|KEGG: 00680+1.2.99.2|KEGG: 00720+1.2.99.2|MetaCyc: PWY-5372|MetaCyc: PWY-6780 HRM2_RS23215 db1d99690b826e404a17ff1b5b1266bf 398 SUPERFAMILY SSF46548 15 90 6.45E-12 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS23215 db1d99690b826e404a17ff1b5b1266bf 398 Pfam PF13183 4Fe-4S dicluster domain 22 91 4.3E-10 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS23215 db1d99690b826e404a17ff1b5b1266bf 398 Pfam PF02754 Cysteine-rich domain 284 372 2.2E-15 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS23215 db1d99690b826e404a17ff1b5b1266bf 398 Pfam PF02754 Cysteine-rich domain 160 243 1.3E-11 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS23215 db1d99690b826e404a17ff1b5b1266bf 398 PANTHER PTHR11921:SF22 6 398 2.0E-93 T 22-04-2016 HRM2_RS23215 db1d99690b826e404a17ff1b5b1266bf 398 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 25 36 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS23215 db1d99690b826e404a17ff1b5b1266bf 398 PANTHER PTHR11921 6 398 2.0E-93 T 22-04-2016 HRM2_RS23215 db1d99690b826e404a17ff1b5b1266bf 398 Gene3D G3DSA:1.10.1060.10 4 117 1.7E-14 T 22-04-2016 HRM2_RS05505 b1953959474b74a64eb1109e964fd04e 189 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 117 123 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HRM2_RS05505 b1953959474b74a64eb1109e964fd04e 189 PANTHER PTHR18895:SF60 1 188 1.1E-39 T 22-04-2016 HRM2_RS05505 b1953959474b74a64eb1109e964fd04e 189 SUPERFAMILY SSF53335 1 180 4.49E-51 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS05505 b1953959474b74a64eb1109e964fd04e 189 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 180 1.6E-52 T 22-04-2016 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HRM2_RS05505 b1953959474b74a64eb1109e964fd04e 189 PANTHER PTHR18895 1 188 1.1E-39 T 22-04-2016 HRM2_RS05505 b1953959474b74a64eb1109e964fd04e 189 PIRSF PIRSF004553 1 184 2.2E-57 T 22-04-2016 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HRM2_RS05505 b1953959474b74a64eb1109e964fd04e 189 Pfam PF03602 Conserved hypothetical protein 95 1 180 4.9E-56 T 22-04-2016 HRM2_RS05505 b1953959474b74a64eb1109e964fd04e 189 Gene3D G3DSA:3.40.50.150 1 184 1.8E-61 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS24935 60c1740eff19673b94c434b8c7076e4d 742 Pfam PF08448 PAS fold 352 456 2.3E-9 T 22-04-2016 IPR013656 PAS fold-4 HRM2_RS24935 60c1740eff19673b94c434b8c7076e4d 742 Gene3D G3DSA:3.30.450.20 331 455 6.7E-13 T 22-04-2016 HRM2_RS24935 60c1740eff19673b94c434b8c7076e4d 742 PANTHER PTHR24423 328 500 6.8E-67 T 22-04-2016 HRM2_RS24935 60c1740eff19673b94c434b8c7076e4d 742 PRINTS PR00344 Bacterial sensor protein C-terminal signature 663 677 6.5E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS24935 60c1740eff19673b94c434b8c7076e4d 742 PRINTS PR00344 Bacterial sensor protein C-terminal signature 694 712 6.5E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS24935 60c1740eff19673b94c434b8c7076e4d 742 PRINTS PR00344 Bacterial sensor protein C-terminal signature 681 691 6.5E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS24935 60c1740eff19673b94c434b8c7076e4d 742 PRINTS PR00344 Bacterial sensor protein C-terminal signature 719 732 6.5E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS24935 60c1740eff19673b94c434b8c7076e4d 742 SUPERFAMILY SSF55785 331 455 1.74E-13 T 22-04-2016 IPR000014 PAS domain HRM2_RS24935 60c1740eff19673b94c434b8c7076e4d 742 PANTHER PTHR24423:SF450 328 500 6.8E-67 T 22-04-2016 HRM2_RS24935 60c1740eff19673b94c434b8c7076e4d 742 SMART SM00387 610 735 9.6E-19 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS24935 60c1740eff19673b94c434b8c7076e4d 742 Pfam PF00512 His Kinase A (phospho-acceptor) domain 474 559 1.5E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS24935 60c1740eff19673b94c434b8c7076e4d 742 SUPERFAMILY SSF55874 553 734 1.15E-33 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS24935 60c1740eff19673b94c434b8c7076e4d 742 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 614 734 3.5E-19 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS24935 60c1740eff19673b94c434b8c7076e4d 742 Pfam PF09084 NMT1/THI5 like 11 218 5.1E-44 T 22-04-2016 IPR015168 SsuA/THI5-like HRM2_RS24935 60c1740eff19673b94c434b8c7076e4d 742 PANTHER PTHR24423:SF450 145 191 6.8E-67 T 22-04-2016 HRM2_RS24935 60c1740eff19673b94c434b8c7076e4d 742 PANTHER PTHR24423:SF450 524 734 6.8E-67 T 22-04-2016 HRM2_RS24935 60c1740eff19673b94c434b8c7076e4d 742 SUPERFAMILY SSF47384 468 561 7.65E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS24935 60c1740eff19673b94c434b8c7076e4d 742 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 340 464 7.1E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS24935 60c1740eff19673b94c434b8c7076e4d 742 SUPERFAMILY SSF53850 7 229 1.22E-26 T 22-04-2016 HRM2_RS24935 60c1740eff19673b94c434b8c7076e4d 742 PANTHER PTHR24423 145 191 6.8E-67 T 22-04-2016 HRM2_RS24935 60c1740eff19673b94c434b8c7076e4d 742 PANTHER PTHR24423 524 734 6.8E-67 T 22-04-2016 HRM2_RS24935 60c1740eff19673b94c434b8c7076e4d 742 Gene3D G3DSA:1.10.287.130 474 557 1.5E-5 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS24935 60c1740eff19673b94c434b8c7076e4d 742 Gene3D G3DSA:3.40.190.10 82 205 2.1E-9 T 22-04-2016 HRM2_RS24935 60c1740eff19673b94c434b8c7076e4d 742 SMART SM00388 472 562 9.9E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS24935 60c1740eff19673b94c434b8c7076e4d 742 Gene3D G3DSA:3.30.565.10 568 733 8.3E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS13440 49eea58be292d77810c780c5a595b3f1 87 Gene3D G3DSA:1.25.40.10 10 57 6.8E-5 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS13440 49eea58be292d77810c780c5a595b3f1 87 SUPERFAMILY SSF48452 4 51 1.77E-6 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS12790 b08f5da02cc683283ddb0f991ebe61c3 248 Gene3D G3DSA:3.40.50.720 9 247 4.9E-83 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS12790 b08f5da02cc683283ddb0f991ebe61c3 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 196 2.6E-4 T 22-04-2016 HRM2_RS12790 b08f5da02cc683283ddb0f991ebe61c3 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 2.5E-14 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS12790 b08f5da02cc683283ddb0f991ebe61c3 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 2.5E-14 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS12790 b08f5da02cc683283ddb0f991ebe61c3 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 2.5E-14 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS12790 b08f5da02cc683283ddb0f991ebe61c3 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 4.9E-45 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS12790 b08f5da02cc683283ddb0f991ebe61c3 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 4.9E-45 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS12790 b08f5da02cc683283ddb0f991ebe61c3 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 4.9E-45 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS12790 b08f5da02cc683283ddb0f991ebe61c3 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 4.9E-45 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS12790 b08f5da02cc683283ddb0f991ebe61c3 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 4.9E-45 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS12790 b08f5da02cc683283ddb0f991ebe61c3 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 4.9E-45 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS12790 b08f5da02cc683283ddb0f991ebe61c3 248 PANTHER PTHR24322:SF328 160 192 2.5E-56 T 22-04-2016 HRM2_RS12790 b08f5da02cc683283ddb0f991ebe61c3 248 PANTHER PTHR24322 15 144 2.5E-56 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS12790 b08f5da02cc683283ddb0f991ebe61c3 248 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 13 247 4.0E-90 T 22-04-2016 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 HRM2_RS12790 b08f5da02cc683283ddb0f991ebe61c3 248 PANTHER PTHR24322:SF328 15 144 2.5E-56 T 22-04-2016 HRM2_RS12790 b08f5da02cc683283ddb0f991ebe61c3 248 SUPERFAMILY SSF51735 10 247 3.77E-80 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS12790 b08f5da02cc683283ddb0f991ebe61c3 248 PANTHER PTHR24322 160 192 2.5E-56 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS12790 b08f5da02cc683283ddb0f991ebe61c3 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 247 6.0E-62 T 22-04-2016 HRM2_RS11425 f644d52c11dd88578e6dc28f43894955 242 PANTHER PTHR24220:SF327 3 239 2.0E-140 T 22-04-2016 HRM2_RS11425 f644d52c11dd88578e6dc28f43894955 242 PIRSF PIRSF039085 1 241 1.3E-117 T 22-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 HRM2_RS11425 f644d52c11dd88578e6dc28f43894955 242 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS11425 f644d52c11dd88578e6dc28f43894955 242 Gene3D G3DSA:3.40.50.300 1 236 2.7E-85 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11425 f644d52c11dd88578e6dc28f43894955 242 SUPERFAMILY SSF52540 1 235 4.58E-82 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11425 f644d52c11dd88578e6dc28f43894955 242 SMART SM00382 26 213 2.2E-20 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS11425 f644d52c11dd88578e6dc28f43894955 242 Pfam PF00005 ABC transporter 18 165 8.4E-38 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS11425 f644d52c11dd88578e6dc28f43894955 242 PANTHER PTHR24220 3 239 2.0E-140 T 22-04-2016 HRM2_RS04760 adb1e9d7da9bb4606517ece2a4b5956d 273 PIRSF PIRSF000363 1 273 1.1E-120 T 22-04-2016 IPR000392 Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL GO:0005524|GO:0016491|GO:0055114 HRM2_RS04760 adb1e9d7da9bb4606517ece2a4b5956d 273 PANTHER PTHR13696 1 257 4.0E-140 T 22-04-2016 HRM2_RS04760 adb1e9d7da9bb4606517ece2a4b5956d 273 PRINTS PR00091 Nitrogenase component II signature 7 20 1.7E-36 T 22-04-2016 IPR000392 Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL GO:0005524|GO:0016491|GO:0055114 HRM2_RS04760 adb1e9d7da9bb4606517ece2a4b5956d 273 PRINTS PR00091 Nitrogenase component II signature 122 137 1.7E-36 T 22-04-2016 IPR000392 Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL GO:0005524|GO:0016491|GO:0055114 HRM2_RS04760 adb1e9d7da9bb4606517ece2a4b5956d 273 PRINTS PR00091 Nitrogenase component II signature 29 44 1.7E-36 T 22-04-2016 IPR000392 Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL GO:0005524|GO:0016491|GO:0055114 HRM2_RS04760 adb1e9d7da9bb4606517ece2a4b5956d 273 PRINTS PR00091 Nitrogenase component II signature 82 96 1.7E-36 T 22-04-2016 IPR000392 Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL GO:0005524|GO:0016491|GO:0055114 HRM2_RS04760 adb1e9d7da9bb4606517ece2a4b5956d 273 Hamap MF_00533 Nitrogenase iron protein [nifH]. 1 273 53.831 T 22-04-2016 IPR005977 Nitrogenase iron protein NifH GO:0009399|GO:0016163|GO:0016612|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 HRM2_RS04760 adb1e9d7da9bb4606517ece2a4b5956d 273 Pfam PF00142 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family 2 271 1.4E-129 T 22-04-2016 HRM2_RS04760 adb1e9d7da9bb4606517ece2a4b5956d 273 PANTHER PTHR13696:SF5 1 257 4.0E-140 T 22-04-2016 HRM2_RS04760 adb1e9d7da9bb4606517ece2a4b5956d 273 ProSitePatterns PS00746 NifH/frxC family signature 1. 84 96 - T 22-04-2016 IPR030655 NifH/chlL conserved site HRM2_RS04760 adb1e9d7da9bb4606517ece2a4b5956d 273 SUPERFAMILY SSF52540 1 269 1.24E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04760 adb1e9d7da9bb4606517ece2a4b5956d 273 ProSitePatterns PS00692 NifH/frxC family signature 2. 123 136 - T 22-04-2016 IPR030655 NifH/chlL conserved site HRM2_RS04760 adb1e9d7da9bb4606517ece2a4b5956d 273 TIGRFAM TIGR01287 nifH: nitrogenase iron protein 2 271 2.7E-136 T 22-04-2016 IPR005977 Nitrogenase iron protein NifH GO:0009399|GO:0016163|GO:0016612|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 HRM2_RS04760 adb1e9d7da9bb4606517ece2a4b5956d 273 Gene3D G3DSA:3.40.50.300 2 268 1.2E-75 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06845 19a2cafff5b3ea8b10d51f985c44263e 343 Gene3D G3DSA:3.40.190.10 130 265 4.1E-19 T 22-04-2016 HRM2_RS06845 19a2cafff5b3ea8b10d51f985c44263e 343 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 27 43 6.9E-69 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS06845 19a2cafff5b3ea8b10d51f985c44263e 343 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 43 64 6.9E-69 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS06845 19a2cafff5b3ea8b10d51f985c44263e 343 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 199 218 6.9E-69 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS06845 19a2cafff5b3ea8b10d51f985c44263e 343 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 144 158 6.9E-69 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS06845 19a2cafff5b3ea8b10d51f985c44263e 343 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 87 100 6.9E-69 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS06845 19a2cafff5b3ea8b10d51f985c44263e 343 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 162 181 6.9E-69 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS06845 19a2cafff5b3ea8b10d51f985c44263e 343 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 288 314 6.9E-69 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS06845 19a2cafff5b3ea8b10d51f985c44263e 343 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 118 134 6.9E-69 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS06845 19a2cafff5b3ea8b10d51f985c44263e 343 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 71 85 6.9E-69 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS06845 19a2cafff5b3ea8b10d51f985c44263e 343 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 243 262 6.9E-69 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS06845 19a2cafff5b3ea8b10d51f985c44263e 343 PANTHER PTHR30222:SF10 1 340 1.2E-120 T 22-04-2016 HRM2_RS06845 19a2cafff5b3ea8b10d51f985c44263e 343 Pfam PF13416 Bacterial extracellular solute-binding protein 36 297 1.0E-35 T 22-04-2016 HRM2_RS06845 19a2cafff5b3ea8b10d51f985c44263e 343 PIRSF PIRSF019574 1 343 5.6E-116 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS06845 19a2cafff5b3ea8b10d51f985c44263e 343 SUPERFAMILY SSF53850 23 340 4.78E-91 T 22-04-2016 HRM2_RS06845 19a2cafff5b3ea8b10d51f985c44263e 343 Gene3D G3DSA:3.40.190.10 23 127 4.1E-58 T 22-04-2016 HRM2_RS06845 19a2cafff5b3ea8b10d51f985c44263e 343 Gene3D G3DSA:3.40.190.10 266 309 4.1E-58 T 22-04-2016 HRM2_RS06845 19a2cafff5b3ea8b10d51f985c44263e 343 PANTHER PTHR30222 1 340 1.2E-120 T 22-04-2016 HRM2_RS07190 4eeae2bc500772d27af95807bc09d012 168 SUPERFAMILY SSF56954 5 144 4.84E-25 T 22-04-2016 HRM2_RS07190 4eeae2bc500772d27af95807bc09d012 168 PANTHER PTHR30026 13 142 4.1E-17 T 22-04-2016 HRM2_RS07190 4eeae2bc500772d27af95807bc09d012 168 Gene3D G3DSA:1.20.1600.10 3 142 7.9E-23 T 22-04-2016 HRM2_RS07190 4eeae2bc500772d27af95807bc09d012 168 PANTHER PTHR30026:SF3 13 142 4.1E-17 T 22-04-2016 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 HRM2_RS07190 4eeae2bc500772d27af95807bc09d012 168 Pfam PF02321 Outer membrane efflux protein 10 140 3.0E-17 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS07975 735bf69c14c42513c335547374368e1f 456 PANTHER PTHR21432 7 444 2.1E-116 T 22-04-2016 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 HRM2_RS07975 735bf69c14c42513c335547374368e1f 456 Gene3D G3DSA:3.40.810.20 197 441 2.1E-47 T 22-04-2016 HRM2_RS07975 735bf69c14c42513c335547374368e1f 456 SUPERFAMILY SSF100950 197 445 1.85E-63 T 22-04-2016 HRM2_RS07975 735bf69c14c42513c335547374368e1f 456 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 281 437 1.3E-61 T 22-04-2016 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain HRM2_RS07975 735bf69c14c42513c335547374368e1f 456 Gene3D G3DSA:3.40.1080.10 10 189 1.6E-49 T 22-04-2016 HRM2_RS07975 735bf69c14c42513c335547374368e1f 456 SUPERFAMILY SSF100950 7 230 9.77E-32 T 22-04-2016 HRM2_RS07975 735bf69c14c42513c335547374368e1f 456 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 9 189 2.6E-20 T 22-04-2016 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 HRM2_RS02505 7d38a66f505ad37e591bee948f78b7af 670 Pfam PF01434 Peptidase family M41 385 592 9.5E-78 T 22-04-2016 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 HRM2_RS02505 7d38a66f505ad37e591bee948f78b7af 670 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 101 593 8.2E-235 T 22-04-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 HRM2_RS02505 7d38a66f505ad37e591bee948f78b7af 670 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 622 36.979 T 22-04-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 HRM2_RS02505 7d38a66f505ad37e591bee948f78b7af 670 Gene3D G3DSA:1.10.8.60 335 408 3.7E-26 T 22-04-2016 HRM2_RS02505 7d38a66f505ad37e591bee948f78b7af 670 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 191 323 8.1E-43 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HRM2_RS02505 7d38a66f505ad37e591bee948f78b7af 670 SUPERFAMILY SSF52540 147 394 1.59E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02505 7d38a66f505ad37e591bee948f78b7af 670 Gene3D G3DSA:3.40.50.300 148 334 2.0E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02505 7d38a66f505ad37e591bee948f78b7af 670 PANTHER PTHR23076 11 593 0.0 T 22-04-2016 HRM2_RS02505 7d38a66f505ad37e591bee948f78b7af 670 Pfam PF06480 FtsH Extracellular 10 95 2.7E-10 T 22-04-2016 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 HRM2_RS02505 7d38a66f505ad37e591bee948f78b7af 670 SUPERFAMILY SSF140990 405 598 9.55E-69 T 22-04-2016 HRM2_RS02505 7d38a66f505ad37e591bee948f78b7af 670 ProSitePatterns PS00674 AAA-protein family signature. 294 312 - T 22-04-2016 IPR003960 ATPase, AAA-type, conserved site GO:0005524 HRM2_RS02505 7d38a66f505ad37e591bee948f78b7af 670 SMART SM00382 187 326 5.3E-22 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS01640 d73c9cc7639622d9c6df78d924b86d6f 219 Gene3D G3DSA:1.10.3720.10 14 213 1.2E-38 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS01640 d73c9cc7639622d9c6df78d924b86d6f 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 209 4.7E-17 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS01640 d73c9cc7639622d9c6df78d924b86d6f 219 PANTHER PTHR30614 3 219 8.8E-72 T 22-04-2016 HRM2_RS01640 d73c9cc7639622d9c6df78d924b86d6f 219 SUPERFAMILY SSF161098 14 199 5.63E-39 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS01640 d73c9cc7639622d9c6df78d924b86d6f 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 108 2.6E-27 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HRM2_RS15040 47151ee4832c3ae645ce415398f6ba0f 144 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 7 143 2.5E-59 T 22-04-2016 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 HRM2_RS15040 47151ee4832c3ae645ce415398f6ba0f 144 PANTHER PTHR11545 4 144 4.0E-68 T 22-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 HRM2_RS15040 47151ee4832c3ae645ce415398f6ba0f 144 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 17 143 28.511 T 22-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 HRM2_RS15040 47151ee4832c3ae645ce415398f6ba0f 144 PIRSF PIRSF002181 2 144 1.5E-52 T 22-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 HRM2_RS15040 47151ee4832c3ae645ce415398f6ba0f 144 Gene3D G3DSA:3.90.1180.10 5 143 7.1E-61 T 22-04-2016 IPR023564 Ribosomal protein L13 domain GO:0003735|GO:0005840|GO:0006412 HRM2_RS15040 47151ee4832c3ae645ce415398f6ba0f 144 ProSitePatterns PS00783 Ribosomal protein L13 signature. 107 129 - T 22-04-2016 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 HRM2_RS15040 47151ee4832c3ae645ce415398f6ba0f 144 SUPERFAMILY SSF52161 6 144 7.06E-57 T 22-04-2016 IPR023564 Ribosomal protein L13 domain GO:0003735|GO:0005840|GO:0006412 HRM2_RS15040 47151ee4832c3ae645ce415398f6ba0f 144 Pfam PF00572 Ribosomal protein L13 16 140 1.4E-55 T 22-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 HRM2_RS02595 9755c4d8b8ce55cbdb03a81ffeef9822 202 SMART SM00421 140 197 3.0E-12 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS02595 9755c4d8b8ce55cbdb03a81ffeef9822 202 ProSitePatterns PS00622 LuxR-type HTH domain signature. 157 184 - T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS02595 9755c4d8b8ce55cbdb03a81ffeef9822 202 SUPERFAMILY SSF46894 126 190 1.94E-15 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HRM2_RS02595 9755c4d8b8ce55cbdb03a81ffeef9822 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 143 157 2.0E-9 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS02595 9755c4d8b8ce55cbdb03a81ffeef9822 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 185 2.0E-9 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS02595 9755c4d8b8ce55cbdb03a81ffeef9822 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 173 2.0E-9 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS02595 9755c4d8b8ce55cbdb03a81ffeef9822 202 Pfam PF00196 Bacterial regulatory proteins, luxR family 142 190 4.4E-14 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS02595 9755c4d8b8ce55cbdb03a81ffeef9822 202 Gene3D G3DSA:1.10.10.10 140 190 1.1E-16 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS13880 16c0ef2c6778bb9cb0532a2cd9ffc83c 425 PANTHER PTHR23512 15 424 5.8E-67 T 22-04-2016 HRM2_RS13880 16c0ef2c6778bb9cb0532a2cd9ffc83c 425 Gene3D G3DSA:1.20.1250.20 15 198 1.0E-28 T 22-04-2016 HRM2_RS13880 16c0ef2c6778bb9cb0532a2cd9ffc83c 425 Pfam PF07690 Major Facilitator Superfamily 26 372 1.3E-33 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS13880 16c0ef2c6778bb9cb0532a2cd9ffc83c 425 PANTHER PTHR23512:SF1 15 424 5.8E-67 T 22-04-2016 HRM2_RS13880 16c0ef2c6778bb9cb0532a2cd9ffc83c 425 Gene3D G3DSA:1.20.1250.20 226 424 2.9E-17 T 22-04-2016 HRM2_RS13880 16c0ef2c6778bb9cb0532a2cd9ffc83c 425 SUPERFAMILY SSF103473 13 417 2.09E-62 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS01310 5a74b6c0e6761b00811310255cb65967 413 SUPERFAMILY SSF53218 180 328 3.53E-38 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS01310 5a74b6c0e6761b00811310255cb65967 413 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 183 320 3.7E-28 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS01310 5a74b6c0e6761b00811310255cb65967 413 PANTHER PTHR10192 1 412 9.4E-137 T 22-04-2016 HRM2_RS01310 5a74b6c0e6761b00811310255cb65967 413 Pfam PF03454 MoeA C-terminal region (domain IV) 340 409 4.5E-15 T 22-04-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 HRM2_RS01310 5a74b6c0e6761b00811310255cb65967 413 SMART SM00852 185 324 1.0E-40 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS01310 5a74b6c0e6761b00811310255cb65967 413 Gene3D G3DSA:3.40.980.10 169 334 2.8E-53 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS01310 5a74b6c0e6761b00811310255cb65967 413 Pfam PF00994 Probable molybdopterin binding domain 185 323 3.6E-25 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS01310 5a74b6c0e6761b00811310255cb65967 413 SUPERFAMILY SSF63882 20 180 4.06E-45 T 22-04-2016 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 HRM2_RS01310 5a74b6c0e6761b00811310255cb65967 413 Pfam PF03453 MoeA N-terminal region (domain I and II) 21 172 3.1E-29 T 22-04-2016 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 HRM2_RS01310 5a74b6c0e6761b00811310255cb65967 413 Gene3D G3DSA:2.170.190.11 49 135 6.5E-26 T 22-04-2016 HRM2_RS01310 5a74b6c0e6761b00811310255cb65967 413 Gene3D G3DSA:2.40.340.10 337 410 8.4E-23 T 22-04-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 HRM2_RS01310 5a74b6c0e6761b00811310255cb65967 413 SUPERFAMILY SSF63867 337 410 3.4E-16 T 22-04-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 HRM2_RS01310 5a74b6c0e6761b00811310255cb65967 413 Gene3D G3DSA:3.90.105.10 136 168 7.0E-15 T 22-04-2016 HRM2_RS11560 456eb60d59d7c170203c5a1b6eae92bf 560 PANTHER PTHR11895 101 556 2.0E-167 T 22-04-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HRM2_RS11560 456eb60d59d7c170203c5a1b6eae92bf 560 ProSitePatterns PS00571 Amidases signature. 245 276 - T 22-04-2016 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HRM2_RS11560 456eb60d59d7c170203c5a1b6eae92bf 560 PANTHER PTHR11895:SF44 101 556 2.0E-167 T 22-04-2016 HRM2_RS11560 456eb60d59d7c170203c5a1b6eae92bf 560 Gene3D G3DSA:3.90.1300.10 94 552 5.2E-129 T 22-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HRM2_RS11560 456eb60d59d7c170203c5a1b6eae92bf 560 Pfam PF01425 Amidase 125 538 3.2E-93 T 22-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HRM2_RS11560 456eb60d59d7c170203c5a1b6eae92bf 560 SUPERFAMILY SSF75304 94 550 1.7E-117 T 22-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HRM2_RS11445 61d08d0693fb0103a77963223249e91d 903 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 476 487 - T 22-04-2016 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 HRM2_RS11445 61d08d0693fb0103a77963223249e91d 903 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 4 900 0.0 T 22-04-2016 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 HRM2_RS11445 61d08d0693fb0103a77963223249e91d 903 SUPERFAMILY SSF51621 538 901 2.32E-116 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HRM2_RS11445 61d08d0693fb0103a77963223249e91d 903 Gene3D G3DSA:3.50.30.10 427 532 1.0E-35 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS11445 61d08d0693fb0103a77963223249e91d 903 PANTHER PTHR22931 1 903 0.0 T 22-04-2016 HRM2_RS11445 61d08d0693fb0103a77963223249e91d 903 Gene3D G3DSA:1.20.80.30 115 212 3.2E-25 T 22-04-2016 HRM2_RS11445 61d08d0693fb0103a77963223249e91d 903 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 544 898 4.5E-83 T 22-04-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 HRM2_RS11445 61d08d0693fb0103a77963223249e91d 903 Gene3D G3DSA:3.30.1490.20 14 114 2.7E-54 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HRM2_RS11445 61d08d0693fb0103a77963223249e91d 903 Gene3D G3DSA:3.30.1490.20 214 257 2.7E-54 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HRM2_RS11445 61d08d0693fb0103a77963223249e91d 903 Gene3D G3DSA:3.20.20.60 558 902 1.1E-127 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HRM2_RS11445 61d08d0693fb0103a77963223249e91d 903 PANTHER PTHR22931:SF9 1 903 0.0 T 22-04-2016 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 HRM2_RS11445 61d08d0693fb0103a77963223249e91d 903 SUPERFAMILY SSF56059 4 404 4.47E-123 T 22-04-2016 HRM2_RS11445 61d08d0693fb0103a77963223249e91d 903 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 21 382 9.8E-57 T 22-04-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 HRM2_RS11445 61d08d0693fb0103a77963223249e91d 903 Gene3D G3DSA:1.10.189.10 368 426 3.3E-22 T 22-04-2016 HRM2_RS11445 61d08d0693fb0103a77963223249e91d 903 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 790 808 - T 22-04-2016 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 HRM2_RS11445 61d08d0693fb0103a77963223249e91d 903 Gene3D G3DSA:3.30.470.20 258 367 1.0E-35 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS11445 61d08d0693fb0103a77963223249e91d 903 PIRSF PIRSF000853 1 903 0.0 T 22-04-2016 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 HRM2_RS11445 61d08d0693fb0103a77963223249e91d 903 Pfam PF00391 PEP-utilising enzyme, mobile domain 448 529 7.8E-24 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS11445 61d08d0693fb0103a77963223249e91d 903 SUPERFAMILY SSF52009 414 535 1.07E-33 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS04300 ee1aa8b4f9a54338e4093d3ca2f48ddd 382 SMART SM00267 255 375 7.5E-9 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS04300 ee1aa8b4f9a54338e4093d3ca2f48ddd 382 SUPERFAMILY SSF55785 33 133 2.69E-9 T 22-04-2016 IPR000014 PAS domain HRM2_RS04300 ee1aa8b4f9a54338e4093d3ca2f48ddd 382 Gene3D G3DSA:3.30.450.20 124 253 2.9E-24 T 22-04-2016 HRM2_RS04300 ee1aa8b4f9a54338e4093d3ca2f48ddd 382 SMART SM00091 138 204 3.3E-9 T 22-04-2016 IPR000014 PAS domain HRM2_RS04300 ee1aa8b4f9a54338e4093d3ca2f48ddd 382 Gene3D G3DSA:3.30.70.270 268 346 3.3E-29 T 22-04-2016 HRM2_RS04300 ee1aa8b4f9a54338e4093d3ca2f48ddd 382 Gene3D G3DSA:3.30.450.20 9 123 1.4E-7 T 22-04-2016 HRM2_RS04300 ee1aa8b4f9a54338e4093d3ca2f48ddd 382 Pfam PF00989 PAS fold 139 252 7.5E-13 T 22-04-2016 IPR013767 PAS fold GO:0006355 HRM2_RS04300 ee1aa8b4f9a54338e4093d3ca2f48ddd 382 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 136 262 3.4E-24 T 22-04-2016 IPR000014 PAS domain HRM2_RS04300 ee1aa8b4f9a54338e4093d3ca2f48ddd 382 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 34 133 3.6E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS04300 ee1aa8b4f9a54338e4093d3ca2f48ddd 382 PANTHER PTHR24423 35 268 4.8E-20 T 22-04-2016 HRM2_RS04300 ee1aa8b4f9a54338e4093d3ca2f48ddd 382 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 266 347 1.2E-31 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS04300 ee1aa8b4f9a54338e4093d3ca2f48ddd 382 Pfam PF13426 PAS domain 30 125 9.3E-5 T 22-04-2016 IPR000014 PAS domain HRM2_RS04300 ee1aa8b4f9a54338e4093d3ca2f48ddd 382 Pfam PF00990 Diguanylate cyclase, GGDEF domain 268 347 1.5E-27 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS04300 ee1aa8b4f9a54338e4093d3ca2f48ddd 382 SUPERFAMILY SSF55785 123 253 3.44E-23 T 22-04-2016 IPR000014 PAS domain HRM2_RS04300 ee1aa8b4f9a54338e4093d3ca2f48ddd 382 SUPERFAMILY SSF55073 271 347 7.85E-27 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS04815 db5d0b392b3db4a8cf708750c404933e 93 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 10 75 2.4E-9 T 22-04-2016 IPR022789 Antitoxin ParD HRM2_RS04815 db5d0b392b3db4a8cf708750c404933e 93 PANTHER PTHR36582 4 75 4.3E-12 T 22-04-2016 HRM2_RS04815 db5d0b392b3db4a8cf708750c404933e 93 SUPERFAMILY SSF47598 6 49 5.23E-11 T 22-04-2016 IPR010985 Ribbon-helix-helix GO:0006355 HRM2_RS04815 db5d0b392b3db4a8cf708750c404933e 93 Gene3D G3DSA:1.10.1220.10 7 48 6.3E-7 T 22-04-2016 IPR013321 Arc-type ribbon-helix-helix GO:0006355 HRM2_RS23995 c0ebc4113d9467cd2cff678cce8803ca 374 PANTHER PTHR30294 1 372 4.7E-201 T 22-04-2016 HRM2_RS23995 c0ebc4113d9467cd2cff678cce8803ca 374 Pfam PF12698 ABC-2 family transporter protein 25 364 7.9E-39 T 22-04-2016 HRM2_RS23995 c0ebc4113d9467cd2cff678cce8803ca 374 PANTHER PTHR30294:SF22 1 372 4.7E-201 T 22-04-2016 HRM2_RS02315 154137a5b7a448e118839815df1645de 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 22-04-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS02315 154137a5b7a448e118839815df1645de 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 6 89 3.3E-40 T 22-04-2016 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 HRM2_RS02315 154137a5b7a448e118839815df1645de 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 23.057 T 22-04-2016 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 HRM2_RS02315 154137a5b7a448e118839815df1645de 89 PANTHER PTHR23321 3 89 9.9E-45 T 22-04-2016 HRM2_RS02315 154137a5b7a448e118839815df1645de 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 1.0E-21 T 22-04-2016 HRM2_RS02315 154137a5b7a448e118839815df1645de 89 SMART SM01387 8 88 2.5E-52 T 22-04-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS02315 154137a5b7a448e118839815df1645de 89 Pfam PF00312 Ribosomal protein S15 8 88 4.2E-38 T 22-04-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS02315 154137a5b7a448e118839815df1645de 89 Gene3D G3DSA:1.10.287.10 5 89 9.4E-40 T 22-04-2016 IPR009068 S15/NS1, RNA-binding Reactome: REACT_71 HRM2_RS02315 154137a5b7a448e118839815df1645de 89 SUPERFAMILY SSF47060 3 89 4.41E-37 T 22-04-2016 IPR009068 S15/NS1, RNA-binding Reactome: REACT_71 HRM2_RS23560 07a3340c967756c1e62d5db277f26819 452 Pfam PF00364 Biotin-requiring enzyme 4 76 8.3E-18 T 22-04-2016 IPR000089 Biotin/lipoyl attachment HRM2_RS23560 07a3340c967756c1e62d5db277f26819 452 SUPERFAMILY SSF51230 3 92 2.62E-25 T 22-04-2016 IPR011053 Single hybrid motif HRM2_RS23560 07a3340c967756c1e62d5db277f26819 452 Gene3D G3DSA:3.30.559.10 225 451 2.7E-76 T 22-04-2016 IPR023213 Chloramphenicol acetyltransferase-like domain HRM2_RS23560 07a3340c967756c1e62d5db277f26819 452 SUPERFAMILY SSF47005 167 206 5.49E-8 T 22-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 HRM2_RS23560 07a3340c967756c1e62d5db277f26819 452 Pfam PF02817 e3 binding domain 173 202 1.1E-9 T 22-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 HRM2_RS23560 07a3340c967756c1e62d5db277f26819 452 Pfam PF02817 e3 binding domain 117 152 6.4E-15 T 22-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 HRM2_RS23560 07a3340c967756c1e62d5db277f26819 452 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 22-04-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site HRM2_RS23560 07a3340c967756c1e62d5db277f26819 452 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 226 451 4.5E-79 T 22-04-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 HRM2_RS23560 07a3340c967756c1e62d5db277f26819 452 Gene3D G3DSA:2.40.50.100 2 86 5.1E-27 T 22-04-2016 HRM2_RS23560 07a3340c967756c1e62d5db277f26819 452 SUPERFAMILY SSF52777 225 451 8.15E-77 T 22-04-2016 HRM2_RS23560 07a3340c967756c1e62d5db277f26819 452 Gene3D G3DSA:4.10.320.10 117 159 1.1E-16 T 22-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 HRM2_RS23560 07a3340c967756c1e62d5db277f26819 452 Gene3D G3DSA:4.10.320.10 163 210 2.1E-12 T 22-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 HRM2_RS23560 07a3340c967756c1e62d5db277f26819 452 PANTHER PTHR23151 207 451 5.8E-136 T 22-04-2016 HRM2_RS23560 07a3340c967756c1e62d5db277f26819 452 PANTHER PTHR23151 3 158 5.8E-136 T 22-04-2016 HRM2_RS23560 07a3340c967756c1e62d5db277f26819 452 SUPERFAMILY SSF47005 114 156 4.97E-11 T 22-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 HRM2_RS05445 b6df7ff23c3316e7d76bea3c72dea910 727 Pfam PF00263 Bacterial type II and III secretion system protein 568 721 3.9E-44 T 22-04-2016 IPR004846 Type II/III secretion system GO:0009306 HRM2_RS05445 b6df7ff23c3316e7d76bea3c72dea910 727 PRINTS PR00811 Bacterial general secretion pathway protein D signature 499 509 2.4E-16 T 22-04-2016 IPR001775 GspD/PilQ family HRM2_RS05445 b6df7ff23c3316e7d76bea3c72dea910 727 PRINTS PR00811 Bacterial general secretion pathway protein D signature 562 586 2.4E-16 T 22-04-2016 IPR001775 GspD/PilQ family HRM2_RS05445 b6df7ff23c3316e7d76bea3c72dea910 727 PRINTS PR00811 Bacterial general secretion pathway protein D signature 685 703 2.4E-16 T 22-04-2016 IPR001775 GspD/PilQ family HRM2_RS05445 b6df7ff23c3316e7d76bea3c72dea910 727 PRINTS PR00811 Bacterial general secretion pathway protein D signature 708 722 2.4E-16 T 22-04-2016 IPR001775 GspD/PilQ family HRM2_RS05445 b6df7ff23c3316e7d76bea3c72dea910 727 Pfam PF07660 Secretin and TonB N terminus short domain 356 402 3.0E-7 T 22-04-2016 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 HRM2_RS05445 b6df7ff23c3316e7d76bea3c72dea910 727 PANTHER PTHR30604 328 727 5.9E-69 T 22-04-2016 HRM2_RS05445 b6df7ff23c3316e7d76bea3c72dea910 727 Pfam PF03958 Bacterial type II/III secretion system short domain 437 497 3.6E-7 T 22-04-2016 IPR005644 NolW-like HRM2_RS08020 77188d05f18af1d02b1284c10e303457 334 Gene3D G3DSA:3.40.190.10 259 327 2.8E-50 T 22-04-2016 HRM2_RS08020 77188d05f18af1d02b1284c10e303457 334 Gene3D G3DSA:3.40.190.10 27 110 2.8E-50 T 22-04-2016 HRM2_RS08020 77188d05f18af1d02b1284c10e303457 334 PANTHER PTHR30024:SF5 2 332 1.8E-66 T 22-04-2016 HRM2_RS08020 77188d05f18af1d02b1284c10e303457 334 SUPERFAMILY SSF53850 27 327 1.17E-54 T 22-04-2016 HRM2_RS08020 77188d05f18af1d02b1284c10e303457 334 PANTHER PTHR30024 2 332 1.8E-66 T 22-04-2016 HRM2_RS08020 77188d05f18af1d02b1284c10e303457 334 Pfam PF16868 NMT1-like family 31 326 2.6E-118 T 22-04-2016 IPR011852 TRAP transporter solute receptor, TAXI family HRM2_RS08020 77188d05f18af1d02b1284c10e303457 334 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 2 326 5.2E-84 T 22-04-2016 IPR011852 TRAP transporter solute receptor, TAXI family HRM2_RS08020 77188d05f18af1d02b1284c10e303457 334 Gene3D G3DSA:3.40.190.10 132 258 6.7E-22 T 22-04-2016 HRM2_RS10570 f30c7df6b75ba1848b3d5e4d32c3e33d 131 PANTHER PTHR39199 1 131 1.3E-53 T 22-04-2016 HRM2_RS10570 f30c7df6b75ba1848b3d5e4d32c3e33d 131 SUPERFAMILY SSF55021 3 66 4.3E-18 T 22-04-2016 HRM2_RS10570 f30c7df6b75ba1848b3d5e4d32c3e33d 131 Pfam PF10000 ACT domain 2 71 2.5E-25 T 22-04-2016 IPR018717 Domain of unknown function DUF2241 HRM2_RS10570 f30c7df6b75ba1848b3d5e4d32c3e33d 131 SUPERFAMILY SSF55021 70 129 1.44E-20 T 22-04-2016 HRM2_RS10570 f30c7df6b75ba1848b3d5e4d32c3e33d 131 PANTHER PTHR39199:SF1 1 131 1.3E-53 T 22-04-2016 HRM2_RS10570 f30c7df6b75ba1848b3d5e4d32c3e33d 131 Gene3D G3DSA:3.30.2130.10 1 130 1.4E-53 T 22-04-2016 HRM2_RS05200 391fded0d5e00d229b75b201a5bf727e 557 PANTHER PTHR10010 8 455 2.0E-59 T 22-04-2016 HRM2_RS05200 391fded0d5e00d229b75b201a5bf727e 557 PANTHER PTHR10010:SF26 8 455 2.0E-59 T 22-04-2016 HRM2_RS05200 391fded0d5e00d229b75b201a5bf727e 557 Pfam PF02690 Na+/Pi-cotransporter 177 265 5.2E-11 T 22-04-2016 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: REACT_15518 HRM2_RS05200 391fded0d5e00d229b75b201a5bf727e 557 Pfam PF02690 Na+/Pi-cotransporter 15 156 8.8E-44 T 22-04-2016 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: REACT_15518 HRM2_RS17435 f7c78cce7560d6599f8b7babe1219c4c 620 Gene3D G3DSA:3.30.450.20 335 474 9.5E-18 T 22-04-2016 HRM2_RS17435 f7c78cce7560d6599f8b7babe1219c4c 620 Pfam PF03600 Citrate transporter 49 565 7.7E-83 T 22-04-2016 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 HRM2_RS17435 f7c78cce7560d6599f8b7babe1219c4c 620 SMART SM00091 337 405 0.007 T 22-04-2016 IPR000014 PAS domain HRM2_RS17435 f7c78cce7560d6599f8b7babe1219c4c 620 PANTHER PTHR10283:SF91 5 308 1.9E-141 T 22-04-2016 HRM2_RS17435 f7c78cce7560d6599f8b7babe1219c4c 620 PANTHER PTHR10283:SF91 468 620 1.9E-141 T 22-04-2016 HRM2_RS17435 f7c78cce7560d6599f8b7babe1219c4c 620 PANTHER PTHR10283:SF91 357 383 1.9E-141 T 22-04-2016 HRM2_RS17435 f7c78cce7560d6599f8b7babe1219c4c 620 Pfam PF13426 PAS domain 349 468 3.7E-8 T 22-04-2016 IPR000014 PAS domain HRM2_RS17435 f7c78cce7560d6599f8b7babe1219c4c 620 SUPERFAMILY SSF55785 340 460 1.73E-10 T 22-04-2016 IPR000014 PAS domain HRM2_RS17435 f7c78cce7560d6599f8b7babe1219c4c 620 PANTHER PTHR10283 5 308 1.9E-141 T 22-04-2016 HRM2_RS17435 f7c78cce7560d6599f8b7babe1219c4c 620 PANTHER PTHR10283 468 620 1.9E-141 T 22-04-2016 HRM2_RS17435 f7c78cce7560d6599f8b7babe1219c4c 620 PANTHER PTHR10283 357 383 1.9E-141 T 22-04-2016 HRM2_RS22585 24c907009320da9028ae9bf05ebc2025 200 SUPERFAMILY SSF102405 1 179 3.82E-59 T 22-04-2016 HRM2_RS22585 24c907009320da9028ae9bf05ebc2025 200 Gene3D G3DSA:3.40.50.450 2 185 4.7E-69 T 22-04-2016 HRM2_RS22585 24c907009320da9028ae9bf05ebc2025 200 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 2 179 5.2E-59 T 22-04-2016 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG HRM2_RS22585 24c907009320da9028ae9bf05ebc2025 200 Pfam PF03641 Possible lysine decarboxylase 46 175 2.4E-39 T 22-04-2016 IPR031100 LOG family HRM2_RS22585 24c907009320da9028ae9bf05ebc2025 200 PANTHER PTHR31223 1 186 2.4E-87 T 22-04-2016 HRM2_RS22585 24c907009320da9028ae9bf05ebc2025 200 PANTHER PTHR31223:SF0 1 186 2.4E-87 T 22-04-2016 HRM2_RS19470 24ce8e1abf0f9c7de185ec23da621500 199 Pfam PF03069 Acetamidase/Formamidase family 44 197 1.6E-16 T 22-04-2016 IPR004304 Acetamidase/Formamidase GO:0016811 HRM2_RS19470 24ce8e1abf0f9c7de185ec23da621500 199 SUPERFAMILY SSF141130 6 110 1.7E-13 T 22-04-2016 HRM2_RS19470 24ce8e1abf0f9c7de185ec23da621500 199 Gene3D G3DSA:2.60.120.580 3 77 9.1E-14 T 22-04-2016 HRM2_RS02125 ea6b3414417af143dd26030686663f76 249 SUPERFAMILY SSF161098 52 232 2.75E-23 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS02125 ea6b3414417af143dd26030686663f76 249 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 232 1.3E-16 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS02125 ea6b3414417af143dd26030686663f76 249 Gene3D G3DSA:1.10.3720.10 51 245 2.9E-11 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS02125 ea6b3414417af143dd26030686663f76 249 PANTHER PTHR30151:SF21 13 248 1.5E-72 T 22-04-2016 HRM2_RS02125 ea6b3414417af143dd26030686663f76 249 PANTHER PTHR30151 13 248 1.5E-72 T 22-04-2016 HRM2_RS03380 1257958521d9cf59c849ff15de2a5bd2 403 SUPERFAMILY SSF54292 37 123 1.48E-20 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 HRM2_RS03380 1257958521d9cf59c849ff15de2a5bd2 403 Pfam PF00175 Oxidoreductase NAD-binding domain 275 384 1.9E-16 T 22-04-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 HRM2_RS03380 1257958521d9cf59c849ff15de2a5bd2 403 SUPERFAMILY SSF52343 253 401 1.31E-35 T 22-04-2016 HRM2_RS03380 1257958521d9cf59c849ff15de2a5bd2 403 TIGRFAM TIGR01941 nqrF: NADH:ubiquinone oxidoreductase, Na(+)-translocating, F subunit 4 403 1.9E-165 T 22-04-2016 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 HRM2_RS03380 1257958521d9cf59c849ff15de2a5bd2 403 PANTHER PTHR19370 61 174 3.6E-102 T 22-04-2016 HRM2_RS03380 1257958521d9cf59c849ff15de2a5bd2 403 Gene3D G3DSA:2.40.30.10 124 262 3.7E-49 T 22-04-2016 HRM2_RS03380 1257958521d9cf59c849ff15de2a5bd2 403 PANTHER PTHR19370:SF32 203 403 3.6E-102 T 22-04-2016 HRM2_RS03380 1257958521d9cf59c849ff15de2a5bd2 403 SUPERFAMILY SSF63380 106 268 8.98E-32 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 HRM2_RS03380 1257958521d9cf59c849ff15de2a5bd2 403 PANTHER PTHR19370:SF32 61 174 3.6E-102 T 22-04-2016 HRM2_RS03380 1257958521d9cf59c849ff15de2a5bd2 403 Gene3D G3DSA:3.10.20.30 37 123 1.1E-18 T 22-04-2016 IPR012675 Beta-grasp domain HRM2_RS03380 1257958521d9cf59c849ff15de2a5bd2 403 Gene3D G3DSA:3.40.50.80 267 403 3.9E-38 T 22-04-2016 HRM2_RS03380 1257958521d9cf59c849ff15de2a5bd2 403 Pfam PF00970 Oxidoreductase FAD-binding domain 205 264 6.6E-6 T 22-04-2016 IPR008333 Oxidoreductase, FAD-binding domain HRM2_RS03380 1257958521d9cf59c849ff15de2a5bd2 403 PANTHER PTHR19370 203 403 3.6E-102 T 22-04-2016 HRM2_RS03380 1257958521d9cf59c849ff15de2a5bd2 403 Hamap MF_00430 Na(+)-translocating NADH-quinone reductase subunit F [nqrF]. 1 403 57.718 T 22-04-2016 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 HRM2_RS03380 1257958521d9cf59c849ff15de2a5bd2 403 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 40 115 1.5E-11 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 HRM2_RS17460 58be77cdb4800497a9398f6e5d6dc4ec 492 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 71 118 1.0E-5 T 22-04-2016 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal HRM2_RS17460 58be77cdb4800497a9398f6e5d6dc4ec 492 PANTHER PTHR22773:SF46 1 490 1.0E-148 T 22-04-2016 HRM2_RS17460 58be77cdb4800497a9398f6e5d6dc4ec 492 Pfam PF00361 Proton-conducting membrane transporter 131 423 5.5E-58 T 22-04-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: REACT_6305 HRM2_RS17460 58be77cdb4800497a9398f6e5d6dc4ec 492 PANTHER PTHR22773 1 490 1.0E-148 T 22-04-2016 HRM2_RS17460 58be77cdb4800497a9398f6e5d6dc4ec 492 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 418 437 3.1E-19 T 22-04-2016 HRM2_RS17460 58be77cdb4800497a9398f6e5d6dc4ec 492 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 241 267 3.1E-19 T 22-04-2016 HRM2_RS17460 58be77cdb4800497a9398f6e5d6dc4ec 492 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 108 128 3.1E-19 T 22-04-2016 HRM2_RS17460 58be77cdb4800497a9398f6e5d6dc4ec 492 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 219 240 3.1E-19 T 22-04-2016 HRM2_RS17460 58be77cdb4800497a9398f6e5d6dc4ec 492 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 78 103 3.1E-19 T 22-04-2016 HRM2_RS21965 d41a9b42c04508dd94623f479e31cf1a 441 PANTHER PTHR37419:SF2 65 426 1.7E-60 T 22-04-2016 HRM2_RS21965 d41a9b42c04508dd94623f479e31cf1a 441 Pfam PF07805 HipA-like N-terminal domain 207 284 3.6E-7 T 22-04-2016 IPR012894 HipA, N-terminal subdomain 2 HRM2_RS21965 d41a9b42c04508dd94623f479e31cf1a 441 Gene3D G3DSA:1.10.10.10 9 55 2.6E-4 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS21965 d41a9b42c04508dd94623f479e31cf1a 441 PANTHER PTHR37419 65 426 1.7E-60 T 22-04-2016 HRM2_RS01245 4873438bd7ac951aea61804ad27d2558 193 PANTHER PTHR11776 1 190 1.9E-57 T 22-04-2016 HRM2_RS01245 4873438bd7ac951aea61804ad27d2558 193 PANTHER PTHR11776:SF1 1 190 1.9E-57 T 22-04-2016 HRM2_RS01245 4873438bd7ac951aea61804ad27d2558 193 Pfam PF00156 Phosphoribosyl transferase domain 55 159 2.7E-10 T 22-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 HRM2_RS01245 4873438bd7ac951aea61804ad27d2558 193 SUPERFAMILY SSF53271 1 186 6.69E-37 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like HRM2_RS01245 4873438bd7ac951aea61804ad27d2558 193 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 1 187 5.0E-61 T 22-04-2016 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22|UniPathway: UPA00602 HRM2_RS01245 4873438bd7ac951aea61804ad27d2558 193 Gene3D G3DSA:3.40.50.2020 1 187 3.3E-49 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like HRM2_RS18470 8a781a816d8f4171d06b8bdaa923e6da 240 Gene3D G3DSA:3.90.226.10 4 204 7.8E-40 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS18470 8a781a816d8f4171d06b8bdaa923e6da 240 PANTHER PTHR11941 4 225 2.5E-50 T 22-04-2016 HRM2_RS18470 8a781a816d8f4171d06b8bdaa923e6da 240 SUPERFAMILY SSF52096 4 219 1.46E-42 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS18470 8a781a816d8f4171d06b8bdaa923e6da 240 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 218 3.3E-27 T 22-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 HRM2_RS18470 8a781a816d8f4171d06b8bdaa923e6da 240 PANTHER PTHR11941:SF75 4 225 2.5E-50 T 22-04-2016 HRM2_RS16400 5952ed88a6adf419351825f6bc86a3e4 295 PANTHER PTHR30349:SF5 1 294 7.9E-99 T 22-04-2016 HRM2_RS16400 5952ed88a6adf419351825f6bc86a3e4 295 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 1 295 54.244 T 22-04-2016 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 HRM2_RS16400 5952ed88a6adf419351825f6bc86a3e4 295 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 7 294 3.1E-106 T 22-04-2016 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 HRM2_RS16400 5952ed88a6adf419351825f6bc86a3e4 295 PANTHER PTHR30349 1 294 7.9E-99 T 22-04-2016 HRM2_RS16400 5952ed88a6adf419351825f6bc86a3e4 295 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 1 295 31.86 T 22-04-2016 IPR023009 Tyrosine recombinase XerC/XerD HRM2_RS16400 5952ed88a6adf419351825f6bc86a3e4 295 Gene3D G3DSA:1.10.150.130 1 96 1.9E-26 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal HRM2_RS16400 5952ed88a6adf419351825f6bc86a3e4 295 SUPERFAMILY SSF56349 3 285 4.12E-56 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HRM2_RS16400 5952ed88a6adf419351825f6bc86a3e4 295 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 5 87 2.6E-24 T 22-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 HRM2_RS16400 5952ed88a6adf419351825f6bc86a3e4 295 Pfam PF00589 Phage integrase family 110 280 4.6E-47 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS16400 5952ed88a6adf419351825f6bc86a3e4 295 Gene3D G3DSA:1.10.443.10 109 284 8.5E-55 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS04990 237d9ffd37c07e1029f8d787e88dbf6c 385 Gene3D G3DSA:3.40.50.1970 1 182 4.0E-53 T 22-04-2016 HRM2_RS04990 237d9ffd37c07e1029f8d787e88dbf6c 385 Gene3D G3DSA:1.20.1090.10 183 383 3.6E-50 T 22-04-2016 HRM2_RS04990 237d9ffd37c07e1029f8d787e88dbf6c 385 PANTHER PTHR11496:SF65 1 382 1.7E-215 T 22-04-2016 HRM2_RS04990 237d9ffd37c07e1029f8d787e88dbf6c 385 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 358 5.1E-88 T 22-04-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 HRM2_RS04990 237d9ffd37c07e1029f8d787e88dbf6c 385 SUPERFAMILY SSF56796 3 381 1.83E-104 T 22-04-2016 HRM2_RS04990 237d9ffd37c07e1029f8d787e88dbf6c 385 PANTHER PTHR11496 1 382 1.7E-215 T 22-04-2016 HRM2_RS04990 237d9ffd37c07e1029f8d787e88dbf6c 385 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 262 282 - T 22-04-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 HRM2_RS05325 c5ae404d835fc65a6b85fd6b7215b955 385 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 229 242 - T 22-04-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Reactome: REACT_13 HRM2_RS05325 c5ae404d835fc65a6b85fd6b7215b955 385 Gene3D G3DSA:3.90.1150.10 252 383 2.4E-39 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS05325 c5ae404d835fc65a6b85fd6b7215b955 385 Gene3D G3DSA:3.40.640.10 46 251 7.3E-64 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS05325 c5ae404d835fc65a6b85fd6b7215b955 385 Pfam PF00155 Aminotransferase class I and II 31 376 4.9E-63 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HRM2_RS05325 c5ae404d835fc65a6b85fd6b7215b955 385 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 197 220 4.1E-11 T 22-04-2016 HRM2_RS05325 c5ae404d835fc65a6b85fd6b7215b955 385 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 114 135 4.1E-11 T 22-04-2016 HRM2_RS05325 c5ae404d835fc65a6b85fd6b7215b955 385 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 92 112 4.1E-11 T 22-04-2016 HRM2_RS05325 c5ae404d835fc65a6b85fd6b7215b955 385 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 161 185 4.1E-11 T 22-04-2016 HRM2_RS05325 c5ae404d835fc65a6b85fd6b7215b955 385 PANTHER PTHR11751 12 383 9.6E-129 T 22-04-2016 HRM2_RS05325 c5ae404d835fc65a6b85fd6b7215b955 385 SUPERFAMILY SSF53383 2 382 2.76E-110 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS05325 c5ae404d835fc65a6b85fd6b7215b955 385 PANTHER PTHR11751:SF28 12 383 9.6E-129 T 22-04-2016 HRM2_RS06340 92624f08764fedde183f7a01c8e3bdce 256 Pfam PF00588 SpoU rRNA Methylase family 10 158 3.1E-27 T 22-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 HRM2_RS06340 92624f08764fedde183f7a01c8e3bdce 256 PIRSF PIRSF004808 6 246 5.7E-56 T 22-04-2016 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 HRM2_RS06340 92624f08764fedde183f7a01c8e3bdce 256 SUPERFAMILY SSF75217 7 167 1.77E-29 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases HRM2_RS06340 92624f08764fedde183f7a01c8e3bdce 256 Gene3D G3DSA:3.40.1280.10 9 163 2.3E-25 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HRM2_RS06340 92624f08764fedde183f7a01c8e3bdce 256 PANTHER PTHR12029:SF54 9 89 4.1E-22 T 22-04-2016 HRM2_RS06340 92624f08764fedde183f7a01c8e3bdce 256 PANTHER PTHR12029:SF54 105 185 4.1E-22 T 22-04-2016 HRM2_RS06340 92624f08764fedde183f7a01c8e3bdce 256 PANTHER PTHR12029 9 89 4.1E-22 T 22-04-2016 HRM2_RS06340 92624f08764fedde183f7a01c8e3bdce 256 PANTHER PTHR12029 105 185 4.1E-22 T 22-04-2016 HRM2_RS03005 bee229a6080ebf91b4c79648b277105d 114 Pfam PF14522 Cytochrome c7 and related cytochrome c 43 113 1.6E-9 T 22-04-2016 HRM2_RS03005 bee229a6080ebf91b4c79648b277105d 114 Gene3D G3DSA:3.90.10.10 39 113 3.5E-13 T 22-04-2016 HRM2_RS03005 bee229a6080ebf91b4c79648b277105d 114 PRINTS PR00609 Class III cytochrome C signature 105 112 1.5E-5 T 22-04-2016 IPR002322 Cytochrome c, class III GO:0009055|GO:0020037 HRM2_RS03005 bee229a6080ebf91b4c79648b277105d 114 PRINTS PR00609 Class III cytochrome C signature 54 61 1.5E-5 T 22-04-2016 IPR002322 Cytochrome c, class III GO:0009055|GO:0020037 HRM2_RS03005 bee229a6080ebf91b4c79648b277105d 114 PRINTS PR00609 Class III cytochrome C signature 87 98 1.5E-5 T 22-04-2016 IPR002322 Cytochrome c, class III GO:0009055|GO:0020037 HRM2_RS03005 bee229a6080ebf91b4c79648b277105d 114 PRINTS PR00609 Class III cytochrome C signature 41 50 1.5E-5 T 22-04-2016 IPR002322 Cytochrome c, class III GO:0009055|GO:0020037 HRM2_RS03005 bee229a6080ebf91b4c79648b277105d 114 SUPERFAMILY SSF48695 28 113 2.64E-12 T 22-04-2016 IPR011031 Multihaem cytochrome HRM2_RS03210 c4f436122667746608673acb578eae8b 281 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 78 277 1.4E-38 T 22-04-2016 HRM2_RS03210 c4f436122667746608673acb578eae8b 281 PANTHER PTHR18895 76 278 9.2E-34 T 22-04-2016 HRM2_RS03210 c4f436122667746608673acb578eae8b 281 PANTHER PTHR18895:SF3 76 278 9.2E-34 T 22-04-2016 HRM2_RS03210 c4f436122667746608673acb578eae8b 281 SUPERFAMILY SSF53335 94 261 2.39E-19 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS03210 c4f436122667746608673acb578eae8b 281 Gene3D G3DSA:3.40.50.150 95 270 7.0E-19 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS10550 521dbc0543f563831ceeb285c1d651ca 238 Gene3D G3DSA:3.40.50.300 3 234 2.9E-63 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10550 521dbc0543f563831ceeb285c1d651ca 238 SMART SM00382 30 217 3.4E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS10550 521dbc0543f563831ceeb285c1d651ca 238 PANTHER PTHR24220:SF568 7 238 6.7E-110 T 22-04-2016 HRM2_RS10550 521dbc0543f563831ceeb285c1d651ca 238 Pfam PF00005 ABC transporter 22 164 5.2E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS10550 521dbc0543f563831ceeb285c1d651ca 238 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS10550 521dbc0543f563831ceeb285c1d651ca 238 SUPERFAMILY SSF52540 4 236 5.43E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10550 521dbc0543f563831ceeb285c1d651ca 238 PANTHER PTHR24220 7 238 6.7E-110 T 22-04-2016 HRM2_RS16320 ff6957f98ed48c49be96a70a397e2de2 227 PANTHER PTHR11692 13 213 5.8E-68 T 22-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 HRM2_RS16320 ff6957f98ed48c49be96a70a397e2de2 227 SUPERFAMILY SSF52335 15 213 2.2E-41 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain HRM2_RS16320 ff6957f98ed48c49be96a70a397e2de2 227 Pfam PF01808 AICARFT/IMPCHase bienzyme 155 214 3.8E-13 T 22-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 HRM2_RS16320 ff6957f98ed48c49be96a70a397e2de2 227 PANTHER PTHR11692:SF2 13 213 5.8E-68 T 22-04-2016 HRM2_RS16320 ff6957f98ed48c49be96a70a397e2de2 227 Gene3D G3DSA:3.40.50.1380 13 207 9.4E-61 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain HRM2_RS16320 ff6957f98ed48c49be96a70a397e2de2 227 SMART SM00851 31 149 1.1E-5 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain HRM2_RS16320 ff6957f98ed48c49be96a70a397e2de2 227 Pfam PF02142 MGS-like domain 41 149 7.5E-11 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain HRM2_RS07805 8d97c7f5351c5ca653fc356d347c8312 624 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 414 434 - T 22-04-2016 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 HRM2_RS07805 8d97c7f5351c5ca653fc356d347c8312 624 PANTHER PTHR11819:SF12 14 490 6.5E-82 T 22-04-2016 HRM2_RS07805 8d97c7f5351c5ca653fc356d347c8312 624 Pfam PF00474 Sodium:solute symporter family 35 432 4.1E-29 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 HRM2_RS07805 8d97c7f5351c5ca653fc356d347c8312 624 PANTHER PTHR11819 14 490 6.5E-82 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 HRM2_RS14675 eb480bdd59f3e639b4ed17a8eec14204 600 PANTHER PTHR19375:SF176 49 62 2.8E-44 T 22-04-2016 HRM2_RS14675 eb480bdd59f3e639b4ed17a8eec14204 600 PANTHER PTHR19375 49 62 2.8E-44 T 22-04-2016 HRM2_RS14675 eb480bdd59f3e639b4ed17a8eec14204 600 PANTHER PTHR19375:SF176 78 301 2.8E-44 T 22-04-2016 HRM2_RS14675 eb480bdd59f3e639b4ed17a8eec14204 600 Pfam PF00012 Hsp70 protein 120 307 2.9E-14 T 22-04-2016 IPR013126 Heat shock protein 70 family HRM2_RS14675 eb480bdd59f3e639b4ed17a8eec14204 600 SUPERFAMILY SSF53067 5 204 8.85E-28 T 22-04-2016 HRM2_RS14675 eb480bdd59f3e639b4ed17a8eec14204 600 Gene3D G3DSA:3.30.420.40 5 224 3.0E-33 T 22-04-2016 HRM2_RS14675 eb480bdd59f3e639b4ed17a8eec14204 600 PRINTS PR00301 70kDa heat shock protein signature 6 19 4.1E-7 T 22-04-2016 IPR013126 Heat shock protein 70 family HRM2_RS14675 eb480bdd59f3e639b4ed17a8eec14204 600 PRINTS PR00301 70kDa heat shock protein signature 162 182 4.1E-7 T 22-04-2016 IPR013126 Heat shock protein 70 family HRM2_RS14675 eb480bdd59f3e639b4ed17a8eec14204 600 PRINTS PR00301 70kDa heat shock protein signature 229 239 4.1E-7 T 22-04-2016 IPR013126 Heat shock protein 70 family HRM2_RS14675 eb480bdd59f3e639b4ed17a8eec14204 600 PANTHER PTHR19375:SF176 5 31 2.8E-44 T 22-04-2016 HRM2_RS14675 eb480bdd59f3e639b4ed17a8eec14204 600 SUPERFAMILY SSF53067 217 364 1.46E-24 T 22-04-2016 HRM2_RS14675 eb480bdd59f3e639b4ed17a8eec14204 600 SUPERFAMILY SSF53067 394 452 1.46E-24 T 22-04-2016 HRM2_RS14675 eb480bdd59f3e639b4ed17a8eec14204 600 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 10 17 - T 22-04-2016 IPR018181 Heat shock protein 70, conserved site HRM2_RS14675 eb480bdd59f3e639b4ed17a8eec14204 600 PANTHER PTHR19375 78 301 2.8E-44 T 22-04-2016 HRM2_RS14675 eb480bdd59f3e639b4ed17a8eec14204 600 PANTHER PTHR19375 5 31 2.8E-44 T 22-04-2016 HRM2_RS14675 eb480bdd59f3e639b4ed17a8eec14204 600 Gene3D G3DSA:3.30.420.40 225 303 1.5E-10 T 22-04-2016 HRM2_RS04515 562f1f4fd91853afd610a3e9ea87ef65 169 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 13 154 4.7E-29 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS04515 562f1f4fd91853afd610a3e9ea87ef65 169 Pfam PF00994 Probable molybdopterin binding domain 17 160 2.2E-27 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS04515 562f1f4fd91853afd610a3e9ea87ef65 169 PANTHER PTHR10192:SF18 7 165 1.6E-56 T 22-04-2016 HRM2_RS04515 562f1f4fd91853afd610a3e9ea87ef65 169 SMART SM00852 17 161 1.2E-17 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS04515 562f1f4fd91853afd610a3e9ea87ef65 169 PIRSF PIRSF006443 1 169 2.4E-55 T 22-04-2016 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 UniPathway: UPA00344 HRM2_RS04515 562f1f4fd91853afd610a3e9ea87ef65 169 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 75 88 - T 22-04-2016 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 UniPathway: UPA00344 HRM2_RS04515 562f1f4fd91853afd610a3e9ea87ef65 169 Gene3D G3DSA:3.40.980.10 7 167 4.0E-44 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS04515 562f1f4fd91853afd610a3e9ea87ef65 169 SUPERFAMILY SSF53218 9 166 2.49E-38 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS04515 562f1f4fd91853afd610a3e9ea87ef65 169 PANTHER PTHR10192 7 165 1.6E-56 T 22-04-2016 HRM2_RS05150 1d9c2dfe485b58523f5ab9a5154be405 118 PANTHER PTHR34299 1 118 3.9E-35 T 22-04-2016 HRM2_RS05150 1d9c2dfe485b58523f5ab9a5154be405 118 PANTHER PTHR34299:SF1 1 118 3.9E-35 T 22-04-2016 HRM2_RS05150 1d9c2dfe485b58523f5ab9a5154be405 118 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 71 82 - T 22-04-2016 IPR000829 Diacylglycerol kinase, prokaryotic GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039 HRM2_RS05150 1d9c2dfe485b58523f5ab9a5154be405 118 Pfam PF01219 Prokaryotic diacylglycerol kinase 17 118 2.8E-33 T 22-04-2016 IPR000829 Diacylglycerol kinase, prokaryotic GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039 HRM2_RS05150 1d9c2dfe485b58523f5ab9a5154be405 118 Gene3D G3DSA:1.10.3830.10 5 118 8.3E-41 T 22-04-2016 HRM2_RS08635 649673036949afbad767949900a3cc71 505 Pfam PF13148 Protein of unknown function (DUF3987) 56 422 8.7E-104 T 22-04-2016 IPR025048 Protein of unknown function DUF3987) HRM2_RS03695 69363da8f574b867bb4d9b86f3c5c57d 426 Pfam PF13447 Seven times multi-haem cytochrome CxxCH 280 339 1.8E-5 T 22-04-2016 HRM2_RS03695 69363da8f574b867bb4d9b86f3c5c57d 426 Pfam PF13447 Seven times multi-haem cytochrome CxxCH 50 217 1.1E-17 T 22-04-2016 HRM2_RS03695 69363da8f574b867bb4d9b86f3c5c57d 426 Gene3D G3DSA:1.20.850.10 279 425 2.6E-52 T 22-04-2016 HRM2_RS03695 69363da8f574b867bb4d9b86f3c5c57d 426 Gene3D G3DSA:1.20.850.10 182 245 2.6E-52 T 22-04-2016 HRM2_RS03695 69363da8f574b867bb4d9b86f3c5c57d 426 SUPERFAMILY SSF48695 279 414 6.02E-69 T 22-04-2016 IPR011031 Multihaem cytochrome HRM2_RS03695 69363da8f574b867bb4d9b86f3c5c57d 426 SUPERFAMILY SSF48695 21 245 6.02E-69 T 22-04-2016 IPR011031 Multihaem cytochrome HRM2_RS03695 69363da8f574b867bb4d9b86f3c5c57d 426 Gene3D G3DSA:1.10.780.10 21 161 1.5E-19 T 22-04-2016 HRM2_RS09950 3d92a56f5506562163a6c1b23b542219 362 PANTHER PTHR33393:SF2 6 243 3.4E-37 T 22-04-2016 HRM2_RS09950 3d92a56f5506562163a6c1b23b542219 362 SMART SM00854 10 246 1.5E-53 T 22-04-2016 IPR019079 Capsule synthesis protein, CapA HRM2_RS09950 3d92a56f5506562163a6c1b23b542219 362 SUPERFAMILY SSF56300 9 246 2.8E-38 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS09950 3d92a56f5506562163a6c1b23b542219 362 Gene3D G3DSA:3.60.21.30 10 241 1.5E-20 T 22-04-2016 HRM2_RS09950 3d92a56f5506562163a6c1b23b542219 362 PANTHER PTHR33393 6 243 3.4E-37 T 22-04-2016 HRM2_RS09950 3d92a56f5506562163a6c1b23b542219 362 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 11 244 1.7E-54 T 22-04-2016 IPR019079 Capsule synthesis protein, CapA HRM2_RS12845 55511cb30fdabcf651b7001455a97a35 117 Gene3D G3DSA:3.40.50.2300 2 115 9.1E-29 T 22-04-2016 HRM2_RS12845 55511cb30fdabcf651b7001455a97a35 117 PANTHER PTHR26402 3 113 8.7E-25 T 22-04-2016 HRM2_RS12845 55511cb30fdabcf651b7001455a97a35 117 SMART SM00448 3 112 6.1E-22 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS12845 55511cb30fdabcf651b7001455a97a35 117 Pfam PF00072 Response regulator receiver domain 5 112 3.9E-23 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS12845 55511cb30fdabcf651b7001455a97a35 117 SUPERFAMILY SSF52172 3 116 3.27E-28 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS11825 2cfb88e1a6de0c2f2ff2eafe39c216cb 205 Pfam PF02508 Rnf-Nqr subunit, membrane protein 9 189 4.0E-56 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 HRM2_RS11825 2cfb88e1a6de0c2f2ff2eafe39c216cb 205 PIRSF PIRSF006102 4 202 1.1E-57 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 HRM2_RS11825 2cfb88e1a6de0c2f2ff2eafe39c216cb 205 PANTHER PTHR30586 2 200 7.9E-71 T 22-04-2016 HRM2_RS07075 438302c54801b8fca66d80931a584fda 215 SUPERFAMILY SSF56507 21 190 1.44E-18 T 22-04-2016 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 HRM2_RS04335 56abe7933dde388e25dc230f53469769 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 412 434 2.0E-7 T 22-04-2016 HRM2_RS04335 56abe7933dde388e25dc230f53469769 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 2.0E-7 T 22-04-2016 HRM2_RS04335 56abe7933dde388e25dc230f53469769 462 PANTHER PTHR10617:SF110 95 321 9.1E-102 T 22-04-2016 HRM2_RS04335 56abe7933dde388e25dc230f53469769 462 PANTHER PTHR10617:SF110 401 455 9.1E-102 T 22-04-2016 HRM2_RS04335 56abe7933dde388e25dc230f53469769 462 PANTHER PTHR10617:SF110 1 74 9.1E-102 T 22-04-2016 HRM2_RS04335 56abe7933dde388e25dc230f53469769 462 PANTHER PTHR10617 95 321 9.1E-102 T 22-04-2016 HRM2_RS04335 56abe7933dde388e25dc230f53469769 462 PANTHER PTHR10617 401 455 9.1E-102 T 22-04-2016 HRM2_RS04335 56abe7933dde388e25dc230f53469769 462 PANTHER PTHR10617 1 74 9.1E-102 T 22-04-2016 HRM2_RS04335 56abe7933dde388e25dc230f53469769 462 Gene3D G3DSA:3.50.50.60 1 260 4.6E-29 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS04335 56abe7933dde388e25dc230f53469769 462 Gene3D G3DSA:3.50.50.60 393 455 4.8E-7 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS04335 56abe7933dde388e25dc230f53469769 462 SUPERFAMILY SSF51905 155 240 1.83E-32 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS04335 56abe7933dde388e25dc230f53469769 462 SUPERFAMILY SSF51905 1 122 1.83E-32 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS04335 56abe7933dde388e25dc230f53469769 462 SUPERFAMILY SSF51905 411 458 1.83E-32 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS04335 56abe7933dde388e25dc230f53469769 462 Pfam PF03486 HI0933-like protein 3 37 4.0E-5 T 22-04-2016 HRM2_RS07275 fc4cda534d477afdca2f8d043a093dbb 232 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 9 226 5.0E-77 T 22-04-2016 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|UniPathway: UPA00232 HRM2_RS07275 fc4cda534d477afdca2f8d043a093dbb 232 PANTHER PTHR10108 1 226 5.4E-76 T 22-04-2016 HRM2_RS07275 fc4cda534d477afdca2f8d043a093dbb 232 PANTHER PTHR10108:SF910 1 226 5.4E-76 T 22-04-2016 HRM2_RS07275 fc4cda534d477afdca2f8d043a093dbb 232 Gene3D G3DSA:3.40.50.150 20 215 1.4E-43 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS07275 fc4cda534d477afdca2f8d043a093dbb 232 Pfam PF13489 Methyltransferase domain 44 199 7.9E-24 T 22-04-2016 HRM2_RS07275 fc4cda534d477afdca2f8d043a093dbb 232 SUPERFAMILY SSF53335 11 226 4.11E-45 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS07275 fc4cda534d477afdca2f8d043a093dbb 232 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 7 232 34.608 T 22-04-2016 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|UniPathway: UPA00232 HRM2_RS18235 1fd883e6d03d0650c8d6c2615f4a47ff 1268 PANTHER PTHR30033 2 498 1.6E-58 T 22-04-2016 HRM2_RS18235 1fd883e6d03d0650c8d6c2615f4a47ff 1268 PANTHER PTHR30033 1122 1268 1.6E-58 T 22-04-2016 HRM2_RS18235 1fd883e6d03d0650c8d6c2615f4a47ff 1268 PRINTS PR01005 Flagellar hook-associated protein signature 217 235 1.9E-6 T 22-04-2016 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 HRM2_RS18235 1fd883e6d03d0650c8d6c2615f4a47ff 1268 PRINTS PR01005 Flagellar hook-associated protein signature 52 74 1.9E-6 T 22-04-2016 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 HRM2_RS18235 1fd883e6d03d0650c8d6c2615f4a47ff 1268 PRINTS PR01005 Flagellar hook-associated protein signature 160 184 1.9E-6 T 22-04-2016 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 HRM2_RS18235 1fd883e6d03d0650c8d6c2615f4a47ff 1268 PRINTS PR01005 Flagellar hook-associated protein signature 14 37 1.9E-6 T 22-04-2016 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 HRM2_RS18235 1fd883e6d03d0650c8d6c2615f4a47ff 1268 SUPERFAMILY SSF64518 911 1157 3.27E-11 T 22-04-2016 HRM2_RS18235 1fd883e6d03d0650c8d6c2615f4a47ff 1268 SUPERFAMILY SSF64518 1191 1266 3.27E-11 T 22-04-2016 HRM2_RS18235 1fd883e6d03d0650c8d6c2615f4a47ff 1268 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 1220 1267 4.8E-10 T 22-04-2016 IPR010930 Flagellar basal-body/hook protein, C-terminal domain HRM2_RS18235 1fd883e6d03d0650c8d6c2615f4a47ff 1268 PANTHER PTHR30033:SF1 2 498 1.6E-58 T 22-04-2016 HRM2_RS18235 1fd883e6d03d0650c8d6c2615f4a47ff 1268 PANTHER PTHR30033:SF1 1122 1268 1.6E-58 T 22-04-2016 HRM2_RS18235 1fd883e6d03d0650c8d6c2615f4a47ff 1268 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 6 314 9.4E-75 T 22-04-2016 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 HRM2_RS19125 9681b9c26fab9d8c3a5c3086391ea1f2 436 Gene3D G3DSA:3.40.640.10 62 315 2.5E-92 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS19125 9681b9c26fab9d8c3a5c3086391ea1f2 436 PANTHER PTHR11986 2 436 3.5E-200 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HRM2_RS19125 9681b9c26fab9d8c3a5c3086391ea1f2 436 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 246 283 - T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HRM2_RS19125 9681b9c26fab9d8c3a5c3086391ea1f2 436 PANTHER PTHR11986:SF17 2 436 3.5E-200 T 22-04-2016 HRM2_RS19125 9681b9c26fab9d8c3a5c3086391ea1f2 436 Gene3D G3DSA:3.90.1150.10 316 434 5.1E-45 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS19125 9681b9c26fab9d8c3a5c3086391ea1f2 436 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 14 432 1.1E-168 T 22-04-2016 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 HRM2_RS19125 9681b9c26fab9d8c3a5c3086391ea1f2 436 SUPERFAMILY SSF53383 23 434 1.41E-140 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS19125 9681b9c26fab9d8c3a5c3086391ea1f2 436 Pfam PF00202 Aminotransferase class-III 26 430 3.1E-129 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HRM2_RS25490 73a48fa98dd6d99081b97db1c3632d60 369 PANTHER PTHR30435 3 237 3.0E-41 T 22-04-2016 HRM2_RS25490 73a48fa98dd6d99081b97db1c3632d60 369 PANTHER PTHR30435:SF15 3 237 3.0E-41 T 22-04-2016 HRM2_RS25490 73a48fa98dd6d99081b97db1c3632d60 369 Pfam PF13860 FlgD Ig-like domain 109 180 8.7E-16 T 22-04-2016 IPR025965 FlgD Ig-like domain HRM2_RS25490 73a48fa98dd6d99081b97db1c3632d60 369 Pfam PF13860 FlgD Ig-like domain 250 326 8.4E-12 T 22-04-2016 IPR025965 FlgD Ig-like domain HRM2_RS25490 73a48fa98dd6d99081b97db1c3632d60 369 Pfam PF03963 Flagellar hook capping protein - N-terminal region 12 78 4.7E-20 T 22-04-2016 IPR005648 Flagellar hook capping protein HRM2_RS22350 f26845562a75c6738314d29530fdbd72 292 PANTHER PTHR17630:SF32 50 292 2.5E-48 T 22-04-2016 HRM2_RS22350 f26845562a75c6738314d29530fdbd72 292 SUPERFAMILY SSF53474 67 292 1.56E-42 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS22350 f26845562a75c6738314d29530fdbd72 292 Gene3D G3DSA:3.40.50.1820 68 292 2.6E-52 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS22350 f26845562a75c6738314d29530fdbd72 292 PANTHER PTHR17630 50 292 2.5E-48 T 22-04-2016 HRM2_RS22350 f26845562a75c6738314d29530fdbd72 292 Pfam PF01738 Dienelactone hydrolase family 82 292 1.9E-45 T 22-04-2016 IPR002925 Dienelactone hydrolase GO:0016787 HRM2_RS04740 37e95092944b693c06cebf466756be3b 161 PANTHER PTHR33567 5 148 4.6E-51 T 22-04-2016 HRM2_RS04740 37e95092944b693c06cebf466756be3b 161 PANTHER PTHR33567:SF1 5 148 4.6E-51 T 22-04-2016 HRM2_RS04740 37e95092944b693c06cebf466756be3b 161 Pfam PF02417 Chromate transporter 13 156 2.7E-28 T 22-04-2016 IPR003370 Chromate transporter GO:0015109|GO:0015703 HRM2_RS07860 949b973e478c0e9fe2d6d7fef117c0d5 368 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 241 252 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS07860 949b973e478c0e9fe2d6d7fef117c0d5 368 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 268 279 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS07860 949b973e478c0e9fe2d6d7fef117c0d5 368 Gene3D G3DSA:3.30.70.20 207 287 1.3E-15 T 22-04-2016 HRM2_RS07860 949b973e478c0e9fe2d6d7fef117c0d5 368 Gene3D G3DSA:3.30.70.20 105 113 1.3E-15 T 22-04-2016 HRM2_RS07860 949b973e478c0e9fe2d6d7fef117c0d5 368 PANTHER PTHR30224 36 332 1.8E-72 T 22-04-2016 HRM2_RS07860 949b973e478c0e9fe2d6d7fef117c0d5 368 Pfam PF12801 4Fe-4S binding domain 195 236 1.4E-6 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS07860 949b973e478c0e9fe2d6d7fef117c0d5 368 Pfam PF12801 4Fe-4S binding domain 86 132 9.0E-11 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS07860 949b973e478c0e9fe2d6d7fef117c0d5 368 SUPERFAMILY SSF54862 100 146 4.19E-20 T 22-04-2016 HRM2_RS07860 949b973e478c0e9fe2d6d7fef117c0d5 368 SUPERFAMILY SSF54862 207 286 4.19E-20 T 22-04-2016 HRM2_RS24130 b9576141f48bd26142afbf2366bd107e 376 Gene3D G3DSA:3.40.630.10 5 186 1.6E-62 T 22-04-2016 HRM2_RS24130 b9576141f48bd26142afbf2366bd107e 376 Gene3D G3DSA:3.40.630.10 313 375 1.6E-62 T 22-04-2016 HRM2_RS24130 b9576141f48bd26142afbf2366bd107e 376 SUPERFAMILY SSF55031 177 290 2.99E-20 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain HRM2_RS24130 b9576141f48bd26142afbf2366bd107e 376 Gene3D G3DSA:3.30.70.360 187 278 4.0E-24 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain HRM2_RS24130 b9576141f48bd26142afbf2366bd107e 376 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 8 361 7.3E-71 T 22-04-2016 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase GO:0016813 HRM2_RS24130 b9576141f48bd26142afbf2366bd107e 376 PANTHER PTHR11014 6 376 1.0E-78 T 22-04-2016 HRM2_RS24130 b9576141f48bd26142afbf2366bd107e 376 Pfam PF01546 Peptidase family M20/M25/M40 70 369 1.7E-28 T 22-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 HRM2_RS24130 b9576141f48bd26142afbf2366bd107e 376 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 104 142 - T 22-04-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 HRM2_RS24130 b9576141f48bd26142afbf2366bd107e 376 SUPERFAMILY SSF53187 289 374 7.6E-57 T 22-04-2016 HRM2_RS24130 b9576141f48bd26142afbf2366bd107e 376 SUPERFAMILY SSF53187 6 177 7.6E-57 T 22-04-2016 HRM2_RS24130 b9576141f48bd26142afbf2366bd107e 376 Pfam PF07687 Peptidase dimerisation domain 175 278 7.3E-22 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain HRM2_RS14645 5df127a46f07f64c19608e53e999781f 372 Gene3D G3DSA:3.40.50.720 206 316 1.8E-25 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS14645 5df127a46f07f64c19608e53e999781f 372 Pfam PF00107 Zinc-binding dehydrogenase 211 322 2.3E-19 T 22-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 HRM2_RS14645 5df127a46f07f64c19608e53e999781f 372 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 43 167 1.2E-5 T 22-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 HRM2_RS14645 5df127a46f07f64c19608e53e999781f 372 PANTHER PTHR11695:SF294 31 66 1.6E-74 T 22-04-2016 HRM2_RS14645 5df127a46f07f64c19608e53e999781f 372 PANTHER PTHR11695:SF294 94 367 1.6E-74 T 22-04-2016 HRM2_RS14645 5df127a46f07f64c19608e53e999781f 372 SMART SM00829 26 367 1.5E-12 T 22-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 HRM2_RS14645 5df127a46f07f64c19608e53e999781f 372 SUPERFAMILY SSF50129 100 205 9.18E-28 T 22-04-2016 IPR011032 GroES-like HRM2_RS14645 5df127a46f07f64c19608e53e999781f 372 SUPERFAMILY SSF50129 14 71 9.18E-28 T 22-04-2016 IPR011032 GroES-like HRM2_RS14645 5df127a46f07f64c19608e53e999781f 372 SUPERFAMILY SSF51735 173 344 3.37E-38 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS14645 5df127a46f07f64c19608e53e999781f 372 Gene3D G3DSA:3.90.180.10 16 205 1.4E-34 T 22-04-2016 IPR011032 GroES-like HRM2_RS14645 5df127a46f07f64c19608e53e999781f 372 PANTHER PTHR11695 31 66 1.6E-74 T 22-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 HRM2_RS14645 5df127a46f07f64c19608e53e999781f 372 PANTHER PTHR11695 94 367 1.6E-74 T 22-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 HRM2_RS14645 5df127a46f07f64c19608e53e999781f 372 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 200 221 - T 22-04-2016 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 HRM2_RS25480 55f83e81c6ef051dc3c9126019a6b304 577 Pfam PF07196 Flagellin hook IN motif 133 188 2.3E-10 T 22-04-2016 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 HRM2_RS25480 55f83e81c6ef051dc3c9126019a6b304 577 PANTHER PTHR30288 4 577 6.0E-59 T 22-04-2016 HRM2_RS25480 55f83e81c6ef051dc3c9126019a6b304 577 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 13 106 1.8E-13 T 22-04-2016 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 HRM2_RS25480 55f83e81c6ef051dc3c9126019a6b304 577 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 340 561 3.1E-37 T 22-04-2016 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 HRM2_RS25480 55f83e81c6ef051dc3c9126019a6b304 577 PANTHER PTHR30288:SF0 4 577 6.0E-59 T 22-04-2016 HRM2_RS17080 6f6aa826d82c2fb5cccc05bd877630a0 146 Gene3D G3DSA:3.10.129.10 8 131 6.0E-24 T 22-04-2016 IPR029069 HotDog domain HRM2_RS17080 6f6aa826d82c2fb5cccc05bd877630a0 146 Pfam PF03061 Thioesterase superfamily 49 123 4.8E-7 T 22-04-2016 IPR006683 Thioesterase domain HRM2_RS17080 6f6aa826d82c2fb5cccc05bd877630a0 146 SUPERFAMILY SSF54637 4 133 3.07E-23 T 22-04-2016 IPR029069 HotDog domain HRM2_RS17080 6f6aa826d82c2fb5cccc05bd877630a0 146 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 28 129 5.3E-12 T 22-04-2016 IPR003736 Phenylacetic acid degradation-related domain HRM2_RS17085 183a13cf451041b40dd7608959713ac3 494 Gene3D G3DSA:3.30.420.40 243 479 2.9E-43 T 22-04-2016 HRM2_RS17085 183a13cf451041b40dd7608959713ac3 494 Gene3D G3DSA:3.30.420.40 3 240 1.6E-40 T 22-04-2016 HRM2_RS17085 183a13cf451041b40dd7608959713ac3 494 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 238 3.3E-37 T 22-04-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 HRM2_RS17085 183a13cf451041b40dd7608959713ac3 494 PIRSF PIRSF000538 1 486 3.4E-86 T 22-04-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 HRM2_RS17085 183a13cf451041b40dd7608959713ac3 494 SUPERFAMILY SSF53067 243 474 4.86E-47 T 22-04-2016 HRM2_RS17085 183a13cf451041b40dd7608959713ac3 494 PANTHER PTHR10196 4 489 2.0E-84 T 22-04-2016 HRM2_RS17085 183a13cf451041b40dd7608959713ac3 494 SUPERFAMILY SSF53067 4 240 4.27E-43 T 22-04-2016 HRM2_RS17085 183a13cf451041b40dd7608959713ac3 494 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 248 430 2.6E-29 T 22-04-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 HRM2_RS22275 cfbc29ced2a07bbc839ae17cd8507cc2 664 PANTHER PTHR32552 8 436 1.9E-39 T 22-04-2016 HRM2_RS22275 cfbc29ced2a07bbc839ae17cd8507cc2 664 PANTHER PTHR32552 456 664 1.9E-39 T 22-04-2016 HRM2_RS22275 cfbc29ced2a07bbc839ae17cd8507cc2 664 Pfam PF00593 TonB dependent receptor 406 661 2.5E-23 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 HRM2_RS22275 cfbc29ced2a07bbc839ae17cd8507cc2 664 Pfam PF07715 TonB-dependent Receptor Plug Domain 52 161 1.0E-20 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 HRM2_RS22275 cfbc29ced2a07bbc839ae17cd8507cc2 664 SUPERFAMILY SSF56935 42 643 7.94E-105 T 22-04-2016 HRM2_RS22275 cfbc29ced2a07bbc839ae17cd8507cc2 664 Gene3D G3DSA:2.170.130.10 51 164 2.5E-32 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 HRM2_RS22275 cfbc29ced2a07bbc839ae17cd8507cc2 664 Gene3D G3DSA:2.40.170.20 165 640 3.0E-65 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 HRM2_RS11210 434a153d18db8e7273f48db8f6586289 377 SUPERFAMILY SSF53850 58 374 5.98E-50 T 22-04-2016 HRM2_RS11210 434a153d18db8e7273f48db8f6586289 377 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 58 372 1.4E-79 T 22-04-2016 IPR005948 Thiamine ABC transporter periplasmic binding protein GO:0005215|GO:0006810|GO:0015888|GO:0030288|GO:0030975 HRM2_RS11210 434a153d18db8e7273f48db8f6586289 377 Gene3D G3DSA:3.40.190.10 28 155 3.4E-23 T 22-04-2016 HRM2_RS11210 434a153d18db8e7273f48db8f6586289 377 Gene3D G3DSA:3.40.190.10 308 368 3.4E-23 T 22-04-2016 HRM2_RS11210 434a153d18db8e7273f48db8f6586289 377 PANTHER PTHR30006:SF3 14 376 1.5E-89 T 22-04-2016 HRM2_RS11210 434a153d18db8e7273f48db8f6586289 377 Pfam PF13343 Bacterial extracellular solute-binding protein 107 364 2.2E-38 T 22-04-2016 HRM2_RS11210 434a153d18db8e7273f48db8f6586289 377 PANTHER PTHR30006 14 376 1.5E-89 T 22-04-2016 HRM2_RS11210 434a153d18db8e7273f48db8f6586289 377 Gene3D G3DSA:3.40.190.10 162 307 9.2E-23 T 22-04-2016 HRM2_RS22525 de00c4810b5a9f0b49faf0f42e0e1422 371 SUPERFAMILY SSF53383 5 358 1.85E-67 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS22525 de00c4810b5a9f0b49faf0f42e0e1422 371 PANTHER PTHR11751:SF338 1 358 7.0E-63 T 22-04-2016 HRM2_RS22525 de00c4810b5a9f0b49faf0f42e0e1422 371 Gene3D G3DSA:3.40.640.10 35 253 1.5E-50 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS22525 de00c4810b5a9f0b49faf0f42e0e1422 371 Pfam PF00155 Aminotransferase class I and II 63 356 4.4E-33 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HRM2_RS22525 de00c4810b5a9f0b49faf0f42e0e1422 371 PANTHER PTHR11751 1 358 7.0E-63 T 22-04-2016 HRM2_RS22525 de00c4810b5a9f0b49faf0f42e0e1422 371 Gene3D G3DSA:3.90.1150.10 254 360 5.6E-20 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS18430 f3f7b6339dc56aaf562d545b3533de11 330 Gene3D G3DSA:3.40.50.300 4 179 1.8E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18430 f3f7b6339dc56aaf562d545b3533de11 330 Pfam PF00158 Sigma-54 interaction domain 8 173 6.2E-69 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS18430 f3f7b6339dc56aaf562d545b3533de11 330 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 221 230 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS18430 f3f7b6339dc56aaf562d545b3533de11 330 Gene3D G3DSA:1.10.10.60 276 321 2.6E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS18430 f3f7b6339dc56aaf562d545b3533de11 330 SUPERFAMILY SSF52540 7 251 8.38E-73 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18430 f3f7b6339dc56aaf562d545b3533de11 330 PANTHER PTHR32071:SF36 2 330 2.0E-157 T 22-04-2016 HRM2_RS18430 f3f7b6339dc56aaf562d545b3533de11 330 SMART SM00382 27 170 3.9E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS18430 f3f7b6339dc56aaf562d545b3533de11 330 Gene3D G3DSA:1.10.8.60 180 257 2.9E-24 T 22-04-2016 HRM2_RS18430 f3f7b6339dc56aaf562d545b3533de11 330 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 285 302 1.0E-7 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS18430 f3f7b6339dc56aaf562d545b3533de11 330 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 302 322 1.0E-7 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS18430 f3f7b6339dc56aaf562d545b3533de11 330 Pfam PF02954 Bacterial regulatory protein, Fis family 279 319 3.2E-12 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS18430 f3f7b6339dc56aaf562d545b3533de11 330 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 93 108 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS18430 f3f7b6339dc56aaf562d545b3533de11 330 PANTHER PTHR32071 2 330 2.0E-157 T 22-04-2016 HRM2_RS18430 f3f7b6339dc56aaf562d545b3533de11 330 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 31 44 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS18430 f3f7b6339dc56aaf562d545b3533de11 330 SUPERFAMILY SSF46689 221 321 2.69E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS08060 5e9b9f7d72eb415861e4203d16610390 119 SMART SM00448 2 113 5.2E-23 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS08060 5e9b9f7d72eb415861e4203d16610390 119 SUPERFAMILY SSF52172 4 118 1.15E-30 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS08060 5e9b9f7d72eb415861e4203d16610390 119 PANTHER PTHR26402 4 118 1.6E-27 T 22-04-2016 HRM2_RS08060 5e9b9f7d72eb415861e4203d16610390 119 Pfam PF00072 Response regulator receiver domain 5 113 7.4E-24 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS08060 5e9b9f7d72eb415861e4203d16610390 119 Gene3D G3DSA:3.40.50.2300 3 118 2.4E-31 T 22-04-2016 HRM2_RS16835 fbdfd300aadce74a6c4cfe580c5d4b50 112 PANTHER PTHR30469:SF10 4 107 1.0E-13 T 22-04-2016 HRM2_RS16835 fbdfd300aadce74a6c4cfe580c5d4b50 112 PANTHER PTHR30469 4 107 1.0E-13 T 22-04-2016 HRM2_RS16835 fbdfd300aadce74a6c4cfe580c5d4b50 112 Pfam PF13533 Biotin-lipoyl like 71 107 1.8E-8 T 22-04-2016 HRM2_RS16835 fbdfd300aadce74a6c4cfe580c5d4b50 112 Gene3D G3DSA:2.40.50.100 70 103 2.4E-7 T 22-04-2016 HRM2_RS16835 fbdfd300aadce74a6c4cfe580c5d4b50 112 SUPERFAMILY SSF111369 59 107 5.62E-8 T 22-04-2016 HRM2_RS22835 61143ecf2d7640ce584829711a5c97e1 212 SUPERFAMILY SSF48150 6 211 1.73E-68 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 HRM2_RS22835 61143ecf2d7640ce584829711a5c97e1 212 PANTHER PTHR10359 6 212 3.8E-76 T 22-04-2016 HRM2_RS22835 61143ecf2d7640ce584829711a5c97e1 212 ProSitePatterns PS01155 Endonuclease III family signature. 104 131 - T 22-04-2016 IPR004036 Endonuclease III-like, conserved site-2 Reactome: REACT_216 HRM2_RS22835 61143ecf2d7640ce584829711a5c97e1 212 SMART SM00478 40 187 8.7E-50 T 22-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 HRM2_RS22835 61143ecf2d7640ce584829711a5c97e1 212 PIRSF PIRSF001435 3 212 1.1E-48 T 22-04-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 HRM2_RS22835 61143ecf2d7640ce584829711a5c97e1 212 Gene3D G3DSA:1.10.340.30 26 124 3.4E-35 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 HRM2_RS22835 61143ecf2d7640ce584829711a5c97e1 212 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 36 170 1.6E-23 T 22-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 HRM2_RS22835 61143ecf2d7640ce584829711a5c97e1 212 TIGRFAM TIGR01083 nth: endonuclease III 8 196 2.6E-72 T 22-04-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 HRM2_RS22835 61143ecf2d7640ce584829711a5c97e1 212 Pfam PF00633 Helix-hairpin-helix motif 102 129 2.1E-6 T 22-04-2016 IPR000445 Helix-hairpin-helix motif GO:0003677 HRM2_RS22835 61143ecf2d7640ce584829711a5c97e1 212 SMART SM00525 188 208 2.2E-4 T 22-04-2016 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: REACT_216 HRM2_RS22835 61143ecf2d7640ce584829711a5c97e1 212 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 189 205 - T 22-04-2016 IPR004035 Endonuclease III, iron-sulphur binding site HRM2_RS22835 61143ecf2d7640ce584829711a5c97e1 212 PANTHER PTHR10359:SF18 6 212 3.8E-76 T 22-04-2016 HRM2_RS22835 61143ecf2d7640ce584829711a5c97e1 212 Hamap MF_00942 Endonuclease III [nth]. 1 211 36.445 T 22-04-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 HRM2_RS22835 61143ecf2d7640ce584829711a5c97e1 212 Gene3D G3DSA:1.10.1670.10 125 210 1.5E-33 T 22-04-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal HRM2_RS10135 6231c79519f61a7dad7e863eb0bb6f86 495 Gene3D G3DSA:2.60.120.10 13 123 5.3E-15 T 22-04-2016 IPR014710 RmlC-like jelly roll fold HRM2_RS10135 6231c79519f61a7dad7e863eb0bb6f86 495 SUPERFAMILY SSF53335 321 439 8.62E-11 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS10135 6231c79519f61a7dad7e863eb0bb6f86 495 SMART SM00100 4 124 0.0022 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain HRM2_RS10135 6231c79519f61a7dad7e863eb0bb6f86 495 Pfam PF12147 Putative methyltransferase 267 381 1.3E-7 T 22-04-2016 IPR022744 Methyltransferase domain, putative HRM2_RS10135 6231c79519f61a7dad7e863eb0bb6f86 495 Gene3D G3DSA:3.40.50.150 308 456 1.5E-10 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS10135 6231c79519f61a7dad7e863eb0bb6f86 495 Pfam PF00027 Cyclic nucleotide-binding domain 24 108 4.7E-11 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain HRM2_RS10135 6231c79519f61a7dad7e863eb0bb6f86 495 SUPERFAMILY SSF51206 13 129 9.56E-18 T 22-04-2016 IPR018490 Cyclic nucleotide-binding-like HRM2_RS15960 80601ade7997add0d579e6554aab0a69 268 PANTHER PTHR10459 36 268 7.2E-46 T 22-04-2016 HRM2_RS15960 80601ade7997add0d579e6554aab0a69 268 Gene3D G3DSA:2.40.50.140 170 268 3.6E-36 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS15960 80601ade7997add0d579e6554aab0a69 268 SUPERFAMILY SSF50249 161 265 1.09E-29 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS15960 80601ade7997add0d579e6554aab0a69 268 PANTHER PTHR10459:SF68 36 268 7.2E-46 T 22-04-2016 HRM2_RS15960 80601ade7997add0d579e6554aab0a69 268 SUPERFAMILY SSF56091 19 187 3.6E-33 T 22-04-2016 HRM2_RS15960 80601ade7997add0d579e6554aab0a69 268 Pfam PF14743 DNA ligase OB-like domain 201 265 9.1E-28 T 22-04-2016 IPR029319 DNA ligase, OB-like domain HRM2_RS15960 80601ade7997add0d579e6554aab0a69 268 Gene3D G3DSA:3.30.1490.70 140 169 4.6E-7 T 22-04-2016 HRM2_RS15960 80601ade7997add0d579e6554aab0a69 268 Gene3D G3DSA:3.30.1490.70 22 43 4.6E-7 T 22-04-2016 HRM2_RS05965 454533737c49c46fb9e64a4fead4be7f 427 Gene3D G3DSA:3.40.80.10 41 180 2.2E-23 T 22-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 HRM2_RS05965 454533737c49c46fb9e64a4fead4be7f 427 SUPERFAMILY SSF55846 45 184 3.53E-26 T 22-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 HRM2_RS05965 454533737c49c46fb9e64a4fead4be7f 427 SMART SM00644 41 179 5.6E-4 T 22-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 HRM2_RS05965 454533737c49c46fb9e64a4fead4be7f 427 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 50 170 1.0E-10 T 22-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 HRM2_RS05965 454533737c49c46fb9e64a4fead4be7f 427 PANTHER PTHR30417 88 183 1.1E-15 T 22-04-2016 HRM2_RS20085 bcb10dec0ebeb3f8170747003dd59e2e 338 PANTHER PTHR30365:SF6 1 337 9.1E-128 T 22-04-2016 HRM2_RS20085 bcb10dec0ebeb3f8170747003dd59e2e 338 PANTHER PTHR30365 1 337 9.1E-128 T 22-04-2016 HRM2_RS20085 bcb10dec0ebeb3f8170747003dd59e2e 338 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 3 221 4.1E-74 T 22-04-2016 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 HRM2_RS20085 bcb10dec0ebeb3f8170747003dd59e2e 338 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 3 327 1.4E-103 T 22-04-2016 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 HRM2_RS20085 bcb10dec0ebeb3f8170747003dd59e2e 338 PIRSF PIRSF000267 1 338 2.8E-119 T 22-04-2016 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 HRM2_RS16510 11af58d8339dc41f6762e180b4f57ad8 243 Gene3D G3DSA:1.10.10.10 2 70 1.5E-25 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS16510 11af58d8339dc41f6762e180b4f57ad8 243 PANTHER PTHR11751 125 144 9.0E-18 T 22-04-2016 HRM2_RS16510 11af58d8339dc41f6762e180b4f57ad8 243 PANTHER PTHR11751 8 76 9.0E-18 T 22-04-2016 HRM2_RS16510 11af58d8339dc41f6762e180b4f57ad8 243 Pfam PF07702 UTRA domain 122 231 8.2E-13 T 22-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 HRM2_RS16510 11af58d8339dc41f6762e180b4f57ad8 243 SMART SM00866 94 232 8.3E-4 T 22-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 HRM2_RS16510 11af58d8339dc41f6762e180b4f57ad8 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 73 1.3E-16 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS16510 11af58d8339dc41f6762e180b4f57ad8 243 PANTHER PTHR11751:SF381 125 144 9.0E-18 T 22-04-2016 HRM2_RS16510 11af58d8339dc41f6762e180b4f57ad8 243 PANTHER PTHR11751:SF381 8 76 9.0E-18 T 22-04-2016 HRM2_RS16510 11af58d8339dc41f6762e180b4f57ad8 243 Gene3D G3DSA:3.40.1410.10 71 236 4.2E-26 T 22-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain HRM2_RS16510 11af58d8339dc41f6762e180b4f57ad8 243 SUPERFAMILY SSF64288 61 237 8.17E-24 T 22-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain HRM2_RS16510 11af58d8339dc41f6762e180b4f57ad8 243 SMART SM00345 14 73 1.2E-19 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS16510 11af58d8339dc41f6762e180b4f57ad8 243 SUPERFAMILY SSF46785 1 83 1.42E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS18190 ff92ca43581cc24e4c7ab97723d7c673 954 SUPERFAMILY SSF53335 82 148 2.32E-5 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS18190 ff92ca43581cc24e4c7ab97723d7c673 954 PANTHER PTHR41786 176 520 4.5E-25 T 22-04-2016 HRM2_RS18190 ff92ca43581cc24e4c7ab97723d7c673 954 Gene3D G3DSA:3.90.1480.10 236 464 1.4E-5 T 22-04-2016 HRM2_RS18190 ff92ca43581cc24e4c7ab97723d7c673 954 Pfam PF01973 Protein of unknown function DUF115 211 384 4.1E-39 T 22-04-2016 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like HRM2_RS18190 ff92ca43581cc24e4c7ab97723d7c673 954 SUPERFAMILY SSF48452 820 950 2.78E-26 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS18190 ff92ca43581cc24e4c7ab97723d7c673 954 Gene3D G3DSA:1.25.40.10 819 948 4.4E-32 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS18190 ff92ca43581cc24e4c7ab97723d7c673 954 Gene3D G3DSA:1.25.40.10 649 710 4.4E-32 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS18190 ff92ca43581cc24e4c7ab97723d7c673 954 Pfam PF14559 Tetratricopeptide repeat 829 890 3.8E-8 T 22-04-2016 HRM2_RS18190 ff92ca43581cc24e4c7ab97723d7c673 954 PANTHER PTHR41786:SF1 176 520 4.5E-25 T 22-04-2016 HRM2_RS18190 ff92ca43581cc24e4c7ab97723d7c673 954 Pfam PF13181 Tetratricopeptide repeat 926 949 0.092 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS18190 ff92ca43581cc24e4c7ab97723d7c673 954 SMART SM00028 677 710 34.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS18190 ff92ca43581cc24e4c7ab97723d7c673 954 SMART SM00028 921 954 11.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS18190 ff92ca43581cc24e4c7ab97723d7c673 954 SMART SM00028 887 920 11.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS18190 ff92ca43581cc24e4c7ab97723d7c673 954 SMART SM00028 819 852 0.0033 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS18190 ff92ca43581cc24e4c7ab97723d7c673 954 SMART SM00028 853 886 17.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS02015 c51e80bae5daf3c9e6e3e46e8daa79b8 399 PANTHER PTHR11732:SF5 1 313 1.3E-174 T 22-04-2016 HRM2_RS02015 c51e80bae5daf3c9e6e3e46e8daa79b8 399 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 353 364 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS02015 c51e80bae5daf3c9e6e3e46e8daa79b8 399 Pfam PF00248 Aldo/keto reductase family 16 267 1.2E-38 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain HRM2_RS02015 c51e80bae5daf3c9e6e3e46e8daa79b8 399 SUPERFAMILY SSF46548 292 379 1.78E-9 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS02015 c51e80bae5daf3c9e6e3e46e8daa79b8 399 Pfam PF13534 4Fe-4S dicluster domain 296 367 3.9E-12 T 22-04-2016 HRM2_RS02015 c51e80bae5daf3c9e6e3e46e8daa79b8 399 Gene3D G3DSA:3.20.20.100 1 298 2.3E-58 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain HRM2_RS02015 c51e80bae5daf3c9e6e3e46e8daa79b8 399 PANTHER PTHR11732 1 313 1.3E-174 T 22-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta HRM2_RS02015 c51e80bae5daf3c9e6e3e46e8daa79b8 399 SUPERFAMILY SSF51430 1 326 1.57E-64 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain HRM2_RS02015 c51e80bae5daf3c9e6e3e46e8daa79b8 399 Gene3D G3DSA:1.10.1060.10 299 380 8.4E-8 T 22-04-2016 HRM2_RS15115 55c9937a23df20b61adc0e9f3097d586 90 SMART SM00834 1 41 3.4E-17 T 22-04-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain HRM2_RS15115 55c9937a23df20b61adc0e9f3097d586 90 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 51 2.5E-19 T 22-04-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain HRM2_RS15115 55c9937a23df20b61adc0e9f3097d586 90 PANTHER PTHR34404:SF2 2 62 1.8E-18 T 22-04-2016 HRM2_RS15115 55c9937a23df20b61adc0e9f3097d586 90 Pfam PF09723 Zinc ribbon domain 1 40 7.1E-16 T 22-04-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain HRM2_RS15115 55c9937a23df20b61adc0e9f3097d586 90 PANTHER PTHR34404 2 62 1.8E-18 T 22-04-2016 HRM2_RS02580 581e7d23e9121a712c3f41ed26e64066 299 Pfam PF00892 EamA-like transporter family 150 285 2.1E-24 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS02580 581e7d23e9121a712c3f41ed26e64066 299 Pfam PF00892 EamA-like transporter family 3 135 1.8E-26 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS02580 581e7d23e9121a712c3f41ed26e64066 299 PANTHER PTHR12715 3 283 6.5E-60 T 22-04-2016 HRM2_RS02580 581e7d23e9121a712c3f41ed26e64066 299 SUPERFAMILY SSF103481 36 139 3.4E-17 T 22-04-2016 HRM2_RS02580 581e7d23e9121a712c3f41ed26e64066 299 PANTHER PTHR12715:SF12 3 283 6.5E-60 T 22-04-2016 HRM2_RS02580 581e7d23e9121a712c3f41ed26e64066 299 SUPERFAMILY SSF103481 188 287 9.68E-15 T 22-04-2016 HRM2_RS03560 a7dea579a8315e6bc93506a042ddaf5e 154 Gene3D G3DSA:3.40.50.2300 4 127 1.1E-36 T 22-04-2016 HRM2_RS03560 a7dea579a8315e6bc93506a042ddaf5e 154 Pfam PF00072 Response regulator receiver domain 7 116 1.1E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS03560 a7dea579a8315e6bc93506a042ddaf5e 154 SUPERFAMILY SSF52172 3 128 5.55E-37 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS03560 a7dea579a8315e6bc93506a042ddaf5e 154 SMART SM00448 4 116 3.5E-33 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS03560 a7dea579a8315e6bc93506a042ddaf5e 154 PANTHER PTHR26402 4 147 8.7E-39 T 22-04-2016 HRM2_RS12235 5f3c3e6e11837059db08618530269aef 101 Pfam PF14451 Mut7-C ubiquitin 2 77 5.6E-6 T 22-04-2016 IPR027798 Ubiquitin Mut7-C domain HRM2_RS12235 5f3c3e6e11837059db08618530269aef 101 SUPERFAMILY SSF54285 20 77 3.18E-7 T 22-04-2016 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp HRM2_RS12235 5f3c3e6e11837059db08618530269aef 101 Gene3D G3DSA:3.10.20.30 21 76 4.8E-9 T 22-04-2016 IPR012675 Beta-grasp domain HRM2_RS10070 a5159820d3b2e53896e4d089cffdfd6a 316 SUPERFAMILY SSF103481 201 304 8.24E-11 T 22-04-2016 HRM2_RS10070 a5159820d3b2e53896e4d089cffdfd6a 316 SUPERFAMILY SSF103481 54 154 1.44E-10 T 22-04-2016 HRM2_RS10070 a5159820d3b2e53896e4d089cffdfd6a 316 Pfam PF00892 EamA-like transporter family 166 300 1.9E-19 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS10070 a5159820d3b2e53896e4d089cffdfd6a 316 Pfam PF00892 EamA-like transporter family 24 153 1.0E-14 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS10070 a5159820d3b2e53896e4d089cffdfd6a 316 PANTHER PTHR12715 22 315 1.1E-38 T 22-04-2016 HRM2_RS14275 38df78e4e951e25d4769bc715e9c4e9e 978 Pfam PF00271 Helicase conserved C-terminal domain 280 382 2.6E-12 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS14275 38df78e4e951e25d4769bc715e9c4e9e 978 Gene3D G3DSA:3.40.50.300 44 232 2.0E-25 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14275 38df78e4e951e25d4769bc715e9c4e9e 978 Pfam PF13482 RNase_H superfamily 850 953 2.2E-5 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS14275 38df78e4e951e25d4769bc715e9c4e9e 978 PANTHER PTHR24031 42 608 3.8E-110 T 22-04-2016 HRM2_RS14275 38df78e4e951e25d4769bc715e9c4e9e 978 Gene3D G3DSA:3.30.420.10 807 972 4.8E-14 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS14275 38df78e4e951e25d4769bc715e9c4e9e 978 SUPERFAMILY SSF52540 66 394 3.98E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14275 38df78e4e951e25d4769bc715e9c4e9e 978 SUPERFAMILY SSF53098 807 958 1.75E-14 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS14275 38df78e4e951e25d4769bc715e9c4e9e 978 PANTHER PTHR24031:SF122 42 608 3.8E-110 T 22-04-2016 HRM2_RS14275 38df78e4e951e25d4769bc715e9c4e9e 978 SMART SM00487 50 260 8.3E-23 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS14275 38df78e4e951e25d4769bc715e9c4e9e 978 Pfam PF09369 Domain of unknown function (DUF1998) 643 722 2.7E-17 T 22-04-2016 IPR018973 DEAD/DEAH-box helicase, putative HRM2_RS14275 38df78e4e951e25d4769bc715e9c4e9e 978 Pfam PF00270 DEAD/DEAH box helicase 56 230 6.9E-21 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HRM2_RS14275 38df78e4e951e25d4769bc715e9c4e9e 978 SMART SM00490 297 382 1.1E-16 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS14275 38df78e4e951e25d4769bc715e9c4e9e 978 Gene3D G3DSA:3.40.50.300 279 396 2.2E-23 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04280 1c5777744dcd45651edb939cde23bb49 746 Gene3D G3DSA:3.40.50.300 1 248 7.8E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04280 1c5777744dcd45651edb939cde23bb49 746 PANTHER PTHR13696:SF72 1 254 5.6E-108 T 22-04-2016 HRM2_RS04280 1c5777744dcd45651edb939cde23bb49 746 SUPERFAMILY SSF53807 323 742 1.48E-70 T 22-04-2016 HRM2_RS04280 1c5777744dcd45651edb939cde23bb49 746 SUPERFAMILY SSF52540 1 246 5.94E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04280 1c5777744dcd45651edb939cde23bb49 746 ProSitePatterns PS00692 NifH/frxC family signature 2. 122 135 - T 22-04-2016 IPR030655 NifH/chlL conserved site HRM2_RS04280 1c5777744dcd45651edb939cde23bb49 746 Gene3D G3DSA:3.40.50.1980 333 475 3.3E-30 T 22-04-2016 HRM2_RS04280 1c5777744dcd45651edb939cde23bb49 746 Gene3D G3DSA:3.40.50.1980 487 594 4.9E-14 T 22-04-2016 HRM2_RS04280 1c5777744dcd45651edb939cde23bb49 746 PRINTS PR00091 Nitrogenase component II signature 82 96 8.9E-33 T 22-04-2016 IPR000392 Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL GO:0005524|GO:0016491|GO:0055114 HRM2_RS04280 1c5777744dcd45651edb939cde23bb49 746 PRINTS PR00091 Nitrogenase component II signature 6 19 8.9E-33 T 22-04-2016 IPR000392 Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL GO:0005524|GO:0016491|GO:0055114 HRM2_RS04280 1c5777744dcd45651edb939cde23bb49 746 PRINTS PR00091 Nitrogenase component II signature 28 43 8.9E-33 T 22-04-2016 IPR000392 Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL GO:0005524|GO:0016491|GO:0055114 HRM2_RS04280 1c5777744dcd45651edb939cde23bb49 746 PRINTS PR00091 Nitrogenase component II signature 121 136 8.9E-33 T 22-04-2016 IPR000392 Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL GO:0005524|GO:0016491|GO:0055114 HRM2_RS04280 1c5777744dcd45651edb939cde23bb49 746 PANTHER PTHR13696 1 254 5.6E-108 T 22-04-2016 HRM2_RS04280 1c5777744dcd45651edb939cde23bb49 746 Gene3D G3DSA:3.40.50.1980 620 740 1.9E-4 T 22-04-2016 HRM2_RS04280 1c5777744dcd45651edb939cde23bb49 746 ProSitePatterns PS00746 NifH/frxC family signature 1. 84 96 - T 22-04-2016 IPR030655 NifH/chlL conserved site HRM2_RS04280 1c5777744dcd45651edb939cde23bb49 746 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 333 733 2.7E-66 T 22-04-2016 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 HRM2_RS04280 1c5777744dcd45651edb939cde23bb49 746 Pfam PF00142 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family 1 266 3.2E-89 T 22-04-2016 HRM2_RS10230 ddf70988b00ffc21e77627bc9a32d17d 187 Pfam PF04002 RadC-like JAB domain 56 178 8.4E-41 T 22-04-2016 IPR025657 RadC-like JAB domain HRM2_RS10230 ddf70988b00ffc21e77627bc9a32d17d 187 PANTHER PTHR30471 50 179 2.3E-45 T 22-04-2016 HRM2_RS10230 ddf70988b00ffc21e77627bc9a32d17d 187 Gene3D G3DSA:3.40.140.10 51 179 2.1E-41 T 22-04-2016 HRM2_RS10230 ddf70988b00ffc21e77627bc9a32d17d 187 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 126 131 - T 22-04-2016 IPR020891 Uncharacterised protein family UPF0758, conserved site HRM2_RS02565 f9647b0a188a3914d8253add87533047 369 Gene3D G3DSA:1.20.120.420 8 165 1.6E-41 T 22-04-2016 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|UniPathway: UPA00904 HRM2_RS02565 f9647b0a188a3914d8253add87533047 369 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 18 352 1.4E-120 T 22-04-2016 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|UniPathway: UPA00904 HRM2_RS02565 f9647b0a188a3914d8253add87533047 369 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 38 351 1.1E-92 T 22-04-2016 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|UniPathway: UPA00904 HRM2_RS02565 f9647b0a188a3914d8253add87533047 369 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 7 362 35.027 T 22-04-2016 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|UniPathway: UPA00904 HRM2_RS02565 f9647b0a188a3914d8253add87533047 369 PANTHER PTHR10233:SF6 5 369 3.7E-124 T 22-04-2016 HRM2_RS02565 f9647b0a188a3914d8253add87533047 369 SUPERFAMILY SSF100950 4 354 2.02E-106 T 22-04-2016 HRM2_RS02565 f9647b0a188a3914d8253add87533047 369 Gene3D G3DSA:3.40.50.10470 166 355 1.5E-59 T 22-04-2016 HRM2_RS02565 f9647b0a188a3914d8253add87533047 369 Pfam PF01008 Initiation factor 2 subunit family 52 351 2.6E-62 T 22-04-2016 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|UniPathway: UPA00904 HRM2_RS02565 f9647b0a188a3914d8253add87533047 369 PANTHER PTHR10233 5 369 3.7E-124 T 22-04-2016 HRM2_RS10385 436db8f3e96fd2ce9bebef3ef485d570 166 Gene3D G3DSA:3.30.70.260 4 81 4.5E-32 T 22-04-2016 HRM2_RS10385 436db8f3e96fd2ce9bebef3ef485d570 166 PANTHER PTHR30239 2 161 4.6E-77 T 22-04-2016 HRM2_RS10385 436db8f3e96fd2ce9bebef3ef485d570 166 SUPERFAMILY SSF55021 82 161 3.55E-26 T 22-04-2016 HRM2_RS10385 436db8f3e96fd2ce9bebef3ef485d570 166 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 4 160 2.9E-63 T 22-04-2016 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HRM2_RS10385 436db8f3e96fd2ce9bebef3ef485d570 166 SUPERFAMILY SSF55021 5 79 3.67E-21 T 22-04-2016 HRM2_RS10385 436db8f3e96fd2ce9bebef3ef485d570 166 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 5 78 7.0E-24 T 22-04-2016 HRM2_RS10385 436db8f3e96fd2ce9bebef3ef485d570 166 Gene3D G3DSA:3.30.70.1150 86 162 1.4E-30 T 22-04-2016 HRM2_RS10385 436db8f3e96fd2ce9bebef3ef485d570 166 Pfam PF13710 ACT domain 15 76 2.3E-14 T 22-04-2016 HRM2_RS10385 436db8f3e96fd2ce9bebef3ef485d570 166 Pfam PF10369 Small subunit of acetolactate synthase 87 159 3.9E-29 T 22-04-2016 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HRM2_RS13660 6b4a6d2e49cd07d8959d6838f43517c0 180 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 8 178 7.9E-80 T 22-04-2016 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 HRM2_RS13660 6b4a6d2e49cd07d8959d6838f43517c0 180 Gene3D G3DSA:3.60.20.10 8 179 5.9E-77 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal HRM2_RS13660 6b4a6d2e49cd07d8959d6838f43517c0 180 PIRSF PIRSF039093 1 180 1.3E-84 T 22-04-2016 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 HRM2_RS13660 6b4a6d2e49cd07d8959d6838f43517c0 180 PANTHER PTHR32194 5 179 1.1E-104 T 22-04-2016 HRM2_RS13660 6b4a6d2e49cd07d8959d6838f43517c0 180 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 7 178 38.099 T 22-04-2016 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 HRM2_RS13660 6b4a6d2e49cd07d8959d6838f43517c0 180 Pfam PF00227 Proteasome subunit 5 176 2.5E-27 T 22-04-2016 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: REACT_11045|Reactome: REACT_13|Reactome: REACT_13635|Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_383|Reactome: REACT_578|Reactome: REACT_6185|Reactome: REACT_6850 HRM2_RS13660 6b4a6d2e49cd07d8959d6838f43517c0 180 SUPERFAMILY SSF56235 4 178 5.5E-59 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal HRM2_RS10915 1bd64a78b4f8c33433ab039db7366244 105 SUPERFAMILY SSF69721 1 105 1.96E-39 T 22-04-2016 IPR025526 DsrC-like domain HRM2_RS10915 1bd64a78b4f8c33433ab039db7366244 105 PIRSF PIRSF006223 4 105 1.0E-33 T 22-04-2016 IPR007453 Sulphur transfer protein DsrC/TusE HRM2_RS10915 1bd64a78b4f8c33433ab039db7366244 105 Gene3D G3DSA:3.30.1420.10 1 41 3.4E-18 T 22-04-2016 HRM2_RS10915 1bd64a78b4f8c33433ab039db7366244 105 PANTHER PTHR37010 1 105 1.1E-28 T 22-04-2016 HRM2_RS10915 1bd64a78b4f8c33433ab039db7366244 105 PANTHER PTHR37010:SF1 1 105 1.1E-28 T 22-04-2016 HRM2_RS10915 1bd64a78b4f8c33433ab039db7366244 105 Gene3D G3DSA:1.10.10.370 42 105 8.0E-27 T 22-04-2016 HRM2_RS10915 1bd64a78b4f8c33433ab039db7366244 105 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 5 105 1.3E-34 T 22-04-2016 IPR007453 Sulphur transfer protein DsrC/TusE HRM2_RS10915 1bd64a78b4f8c33433ab039db7366244 105 Pfam PF04358 DsrC like protein 5 105 7.7E-37 T 22-04-2016 IPR007453 Sulphur transfer protein DsrC/TusE HRM2_RS01980 7f26127fe724d315c9f641cad807a6e2 529 Pfam PF13193 AMP-binding enzyme C-terminal domain 433 506 6.1E-11 T 22-04-2016 IPR025110 AMP-binding enzyme C-terminal domain HRM2_RS01980 7f26127fe724d315c9f641cad807a6e2 529 Gene3D G3DSA:3.40.50.980 3 178 2.0E-34 T 22-04-2016 HRM2_RS01980 7f26127fe724d315c9f641cad807a6e2 529 Gene3D G3DSA:3.30.300.30 419 516 2.6E-22 T 22-04-2016 HRM2_RS01980 7f26127fe724d315c9f641cad807a6e2 529 Gene3D G3DSA:2.30.38.10 344 418 9.2E-26 T 22-04-2016 HRM2_RS01980 7f26127fe724d315c9f641cad807a6e2 529 Gene3D G3DSA:3.40.50.980 179 332 1.2E-29 T 22-04-2016 HRM2_RS01980 7f26127fe724d315c9f641cad807a6e2 529 ProSitePatterns PS00455 Putative AMP-binding domain signature. 173 184 - T 22-04-2016 IPR020845 AMP-binding, conserved site HRM2_RS01980 7f26127fe724d315c9f641cad807a6e2 529 Pfam PF00501 AMP-binding enzyme 8 424 5.5E-91 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS01980 7f26127fe724d315c9f641cad807a6e2 529 SUPERFAMILY SSF56801 3 518 1.57E-129 T 22-04-2016 HRM2_RS01980 7f26127fe724d315c9f641cad807a6e2 529 PANTHER PTHR24096 3 514 5.4E-129 T 22-04-2016 HRM2_RS20115 b3609de9142603054053cf2d39685927 642 SUPERFAMILY SSF52518 17 192 5.56E-42 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS20115 b3609de9142603054053cf2d39685927 642 SUPERFAMILY SSF52518 377 555 1.3E-32 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS20115 b3609de9142603054053cf2d39685927 642 PANTHER PTHR18968:SF91 289 628 1.5E-54 T 22-04-2016 HRM2_RS20115 b3609de9142603054053cf2d39685927 642 Gene3D G3DSA:3.40.50.970 377 557 1.9E-33 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS20115 b3609de9142603054053cf2d39685927 642 PANTHER PTHR18968 289 628 1.5E-54 T 22-04-2016 HRM2_RS20115 b3609de9142603054053cf2d39685927 642 Pfam PF00037 4Fe-4S binding domain 604 624 1.0E-4 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS20115 b3609de9142603054053cf2d39685927 642 PIRSF PIRSF006439 4 630 7.4E-176 T 22-04-2016 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 HRM2_RS20115 b3609de9142603054053cf2d39685927 642 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 407 548 4.3E-27 T 22-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HRM2_RS20115 b3609de9142603054053cf2d39685927 642 SUPERFAMILY SSF54862 561 626 5.33E-9 T 22-04-2016 HRM2_RS20115 b3609de9142603054053cf2d39685927 642 Gene3D G3DSA:3.40.50.970 15 190 8.9E-41 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS20115 b3609de9142603054053cf2d39685927 642 Gene3D G3DSA:3.30.70.20 558 625 5.8E-6 T 22-04-2016 HRM2_RS20115 b3609de9142603054053cf2d39685927 642 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 27 192 8.2E-10 T 22-04-2016 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 HRM2_RS09300 a329d3f78e207214c9bc4b9fa89376e6 597 Gene3D G3DSA:3.40.50.300 8 252 9.9E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09300 a329d3f78e207214c9bc4b9fa89376e6 597 SUPERFAMILY SSF52540 4 203 1.88E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09300 a329d3f78e207214c9bc4b9fa89376e6 597 Pfam PF00005 ABC transporter 310 443 7.3E-22 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS09300 a329d3f78e207214c9bc4b9fa89376e6 597 Pfam PF00005 ABC transporter 21 153 1.3E-21 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS09300 a329d3f78e207214c9bc4b9fa89376e6 597 ProSitePatterns PS00211 ABC transporters family signature. 415 429 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS09300 a329d3f78e207214c9bc4b9fa89376e6 597 PANTHER PTHR19211 8 535 7.5E-137 T 22-04-2016 HRM2_RS09300 a329d3f78e207214c9bc4b9fa89376e6 597 Gene3D G3DSA:3.40.50.300 293 511 1.2E-37 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09300 a329d3f78e207214c9bc4b9fa89376e6 597 SMART SM00382 318 489 1.1E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS09300 a329d3f78e207214c9bc4b9fa89376e6 597 SMART SM00382 29 244 1.3E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS09300 a329d3f78e207214c9bc4b9fa89376e6 597 SUPERFAMILY SSF52540 275 487 1.56E-39 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09300 a329d3f78e207214c9bc4b9fa89376e6 597 PANTHER PTHR19211:SF45 8 535 7.5E-137 T 22-04-2016 HRM2_RS09300 a329d3f78e207214c9bc4b9fa89376e6 597 Pfam PF16326 ABC transporter C-terminal domain 525 593 1.4E-19 T 22-04-2016 IPR032524 ABC transporter Uup, C-terminal GO:0003677 HRM2_RS09300 a329d3f78e207214c9bc4b9fa89376e6 597 Pfam PF12848 ABC transporter 206 265 9.0E-5 T 22-04-2016 IPR032781 ABC-transporter extension domain HRM2_RS19850 cf8f300dc6848640b7c21884e84065bc 473 Gene3D G3DSA:2.160.10.10 248 378 5.8E-24 T 22-04-2016 HRM2_RS19850 cf8f300dc6848640b7c21884e84065bc 473 SUPERFAMILY SSF51161 251 376 3.33E-13 T 22-04-2016 IPR011004 Trimeric LpxA-like HRM2_RS19850 cf8f300dc6848640b7c21884e84065bc 473 Gene3D G3DSA:2.160.10.10 42 228 3.6E-124 T 22-04-2016 HRM2_RS19850 cf8f300dc6848640b7c21884e84065bc 473 Gene3D G3DSA:2.160.10.10 414 473 3.6E-124 T 22-04-2016 HRM2_RS19535 8b111f802359fd794444c65496e0200b 209 PANTHER PTHR11220 24 205 2.6E-34 T 22-04-2016 IPR006917 SOUL haem-binding protein HRM2_RS19535 8b111f802359fd794444c65496e0200b 209 SUPERFAMILY SSF55136 15 204 1.15E-51 T 22-04-2016 IPR011256 Regulatory factor, effector binding domain HRM2_RS19535 8b111f802359fd794444c65496e0200b 209 Pfam PF04832 SOUL heme-binding protein 24 203 9.0E-45 T 22-04-2016 IPR006917 SOUL haem-binding protein HRM2_RS19535 8b111f802359fd794444c65496e0200b 209 PANTHER PTHR11220:SF35 24 205 2.6E-34 T 22-04-2016 HRM2_RS00400 59595246fdc63c5f55aab7e59e439baf 73 Pfam PF08984 Domain of unknown function (DUF1858) 7 58 5.2E-13 T 22-04-2016 IPR015077 Domain of unknown function DUF1858 HRM2_RS00400 59595246fdc63c5f55aab7e59e439baf 73 PANTHER PTHR39341 6 70 3.8E-13 T 22-04-2016 HRM2_RS00400 59595246fdc63c5f55aab7e59e439baf 73 Gene3D G3DSA:1.10.3910.10 8 31 7.9E-4 T 22-04-2016 IPR015077 Domain of unknown function DUF1858 HRM2_RS00400 59595246fdc63c5f55aab7e59e439baf 73 SUPERFAMILY SSF140683 7 67 7.59E-14 T 22-04-2016 HRM2_RS00400 59595246fdc63c5f55aab7e59e439baf 73 TIGRFAM TIGR03980 prismane_assoc: hybrid cluster protein-associated redox disulfide domain 7 62 2.3E-20 T 22-04-2016 IPR023883 Conserved hypothetical protein CHP03980, redox-disulphide HRM2_RS22110 bfc748a7eb46ca4781fe83cc880c47ec 312 PANTHER PTHR10617:SF101 5 292 1.1E-27 T 22-04-2016 HRM2_RS22110 bfc748a7eb46ca4781fe83cc880c47ec 312 Gene3D G3DSA:3.30.9.10 159 294 6.9E-21 T 22-04-2016 HRM2_RS22110 bfc748a7eb46ca4781fe83cc880c47ec 312 PANTHER PTHR10617 5 292 1.1E-27 T 22-04-2016 HRM2_RS22110 bfc748a7eb46ca4781fe83cc880c47ec 312 Pfam PF01494 FAD binding domain 4 56 1.3E-5 T 22-04-2016 IPR002938 FAD-binding domain GO:0071949 HRM2_RS22110 bfc748a7eb46ca4781fe83cc880c47ec 312 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 2.3E-6 T 22-04-2016 HRM2_RS22110 bfc748a7eb46ca4781fe83cc880c47ec 312 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 257 272 2.3E-6 T 22-04-2016 HRM2_RS22110 bfc748a7eb46ca4781fe83cc880c47ec 312 SUPERFAMILY SSF51905 244 295 2.64E-28 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS22110 bfc748a7eb46ca4781fe83cc880c47ec 312 SUPERFAMILY SSF51905 5 150 2.64E-28 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS22110 bfc748a7eb46ca4781fe83cc880c47ec 312 Gene3D G3DSA:3.50.50.60 3 54 3.1E-11 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS22110 bfc748a7eb46ca4781fe83cc880c47ec 312 Gene3D G3DSA:3.50.50.60 91 158 3.1E-11 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS09150 e99d05f01b0f2b6d047ccb41cae02a23 364 SUPERFAMILY SSF50331 243 360 1.98E-16 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal HRM2_RS09150 e99d05f01b0f2b6d047ccb41cae02a23 364 PANTHER PTHR24220:SF151 5 304 1.8E-89 T 22-04-2016 HRM2_RS09150 e99d05f01b0f2b6d047ccb41cae02a23 364 PANTHER PTHR24220 5 304 1.8E-89 T 22-04-2016 HRM2_RS09150 e99d05f01b0f2b6d047ccb41cae02a23 364 Gene3D G3DSA:3.40.50.300 6 240 9.1E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09150 e99d05f01b0f2b6d047ccb41cae02a23 364 SUPERFAMILY SSF52540 21 251 7.23E-63 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09150 e99d05f01b0f2b6d047ccb41cae02a23 364 SMART SM00382 34 218 4.2E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS09150 e99d05f01b0f2b6d047ccb41cae02a23 364 Gene3D G3DSA:2.40.50.140 296 349 3.2E-7 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS09150 e99d05f01b0f2b6d047ccb41cae02a23 364 Pfam PF00005 ABC transporter 33 168 2.0E-20 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS09150 e99d05f01b0f2b6d047ccb41cae02a23 364 Pfam PF08402 TOBE domain 287 357 2.4E-6 T 22-04-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 HRM2_RS21195 008376edbd8394f0cb4760e9f8e24951 151 Gene3D G3DSA:2.30.110.10 14 140 3.7E-16 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 HRM2_RS21195 008376edbd8394f0cb4760e9f8e24951 151 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 99 5.0E-11 T 22-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 HRM2_RS21195 008376edbd8394f0cb4760e9f8e24951 151 SUPERFAMILY SSF50475 9 145 8.42E-22 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 HRM2_RS06680 58f4c014926a177652a9b5251b549f26 269 PANTHER PTHR24220:SF582 6 256 1.0E-85 T 22-04-2016 HRM2_RS06680 58f4c014926a177652a9b5251b549f26 269 SUPERFAMILY SSF52540 4 233 7.57E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06680 58f4c014926a177652a9b5251b549f26 269 Gene3D G3DSA:3.40.50.300 4 234 3.7E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06680 58f4c014926a177652a9b5251b549f26 269 SMART SM00382 29 218 5.4E-14 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS06680 58f4c014926a177652a9b5251b549f26 269 PANTHER PTHR24220 6 256 1.0E-85 T 22-04-2016 HRM2_RS06680 58f4c014926a177652a9b5251b549f26 269 Pfam PF00005 ABC transporter 20 169 4.9E-27 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS15990 cacf60b6edb78b6b5bb595a8caab6559 536 Pfam PF05681 Fumarate hydratase (Fumerase) 49 325 1.6E-86 T 22-04-2016 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 HRM2_RS15990 cacf60b6edb78b6b5bb595a8caab6559 536 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 370 533 3.6E-55 T 22-04-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 HRM2_RS15990 cacf60b6edb78b6b5bb595a8caab6559 536 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 74 325 7.6E-35 T 22-04-2016 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 HRM2_RS15990 cacf60b6edb78b6b5bb595a8caab6559 536 PIRSF PIRSF001394 28 536 2.2E-204 T 22-04-2016 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS15990 cacf60b6edb78b6b5bb595a8caab6559 536 SUPERFAMILY SSF117457 358 532 3.92E-60 T 22-04-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 HRM2_RS15990 cacf60b6edb78b6b5bb595a8caab6559 536 ProSitePatterns PS00163 Fumarate lyases signature. 453 462 - T 22-04-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 HRM2_RS15990 cacf60b6edb78b6b5bb595a8caab6559 536 PANTHER PTHR30389:SF0 1 536 0.0 T 22-04-2016 HRM2_RS15990 cacf60b6edb78b6b5bb595a8caab6559 536 Gene3D G3DSA:3.20.130.10 350 533 1.1E-68 T 22-04-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 HRM2_RS15990 cacf60b6edb78b6b5bb595a8caab6559 536 PANTHER PTHR30389 1 536 0.0 T 22-04-2016 HRM2_RS15990 cacf60b6edb78b6b5bb595a8caab6559 536 Pfam PF05683 Fumarase C-terminus 331 534 1.4E-87 T 22-04-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 HRM2_RS17360 e731e497929c80e589797a93880ac3be 135 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 131 20.502 T 22-04-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 HRM2_RS17360 e731e497929c80e589797a93880ac3be 135 Gene3D G3DSA:2.60.15.10 5 90 8.8E-27 T 22-04-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 HRM2_RS17360 e731e497929c80e589797a93880ac3be 135 Gene3D G3DSA:1.20.5.440 92 133 5.0E-13 T 22-04-2016 HRM2_RS17360 e731e497929c80e589797a93880ac3be 135 PANTHER PTHR13822 1 133 1.4E-30 T 22-04-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 HRM2_RS17360 e731e497929c80e589797a93880ac3be 135 SUPERFAMILY SSF46604 89 134 3.4E-7 T 22-04-2016 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain HRM2_RS17360 e731e497929c80e589797a93880ac3be 135 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 7 84 2.0E-27 T 22-04-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 HRM2_RS17360 e731e497929c80e589797a93880ac3be 135 SUPERFAMILY SSF51344 5 86 4.05E-22 T 22-04-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 HRM2_RS17360 e731e497929c80e589797a93880ac3be 135 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 18 90 4.0E-17 T 22-04-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 HRM2_RS17360 e731e497929c80e589797a93880ac3be 135 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 6 133 1.6E-32 T 22-04-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 HRM2_RS17360 e731e497929c80e589797a93880ac3be 135 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 89 133 2.8E-11 T 22-04-2016 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain HRM2_RS12225 eb32880965d54153fb586f7a2b1acc3a 228 SMART SM00116 10 57 9.0E-8 T 22-04-2016 IPR000644 CBS domain HRM2_RS12225 eb32880965d54153fb586f7a2b1acc3a 228 SMART SM00116 86 134 6.0E-7 T 22-04-2016 IPR000644 CBS domain HRM2_RS12225 eb32880965d54153fb586f7a2b1acc3a 228 Gene3D G3DSA:3.10.580.10 1 134 4.2E-30 T 22-04-2016 HRM2_RS12225 eb32880965d54153fb586f7a2b1acc3a 228 PANTHER PTHR11911 77 135 2.2E-29 T 22-04-2016 HRM2_RS12225 eb32880965d54153fb586f7a2b1acc3a 228 PANTHER PTHR11911 1 61 2.2E-29 T 22-04-2016 HRM2_RS12225 eb32880965d54153fb586f7a2b1acc3a 228 Pfam PF00571 CBS domain 80 133 2.2E-10 T 22-04-2016 IPR000644 CBS domain HRM2_RS12225 eb32880965d54153fb586f7a2b1acc3a 228 Pfam PF00571 CBS domain 3 56 1.8E-11 T 22-04-2016 IPR000644 CBS domain HRM2_RS12225 eb32880965d54153fb586f7a2b1acc3a 228 SUPERFAMILY SSF54631 1 135 5.43E-32 T 22-04-2016 HRM2_RS01940 8f7270cf73db63f1a25797e98607b562 123 SUPERFAMILY SSF50475 1 122 1.1E-33 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 HRM2_RS01940 8f7270cf73db63f1a25797e98607b562 123 Gene3D G3DSA:2.30.110.10 1 122 2.8E-46 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 HRM2_RS01940 8f7270cf73db63f1a25797e98607b562 123 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 3 95 1.5E-8 T 22-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 HRM2_RS02415 2ee1d47052af0e737d5fe267c7b2c456 713 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 26 236 8.8E-46 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS02415 2ee1d47052af0e737d5fe267c7b2c456 713 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 260 697 1.1E-107 T 22-04-2016 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS02415 2ee1d47052af0e737d5fe267c7b2c456 713 PANTHER PTHR30038:SF0 665 702 1.5E-93 T 22-04-2016 HRM2_RS02415 2ee1d47052af0e737d5fe267c7b2c456 713 PANTHER PTHR30038:SF0 19 554 1.5E-93 T 22-04-2016 HRM2_RS02415 2ee1d47052af0e737d5fe267c7b2c456 713 PANTHER PTHR30038:SF0 571 647 1.5E-93 T 22-04-2016 HRM2_RS02415 2ee1d47052af0e737d5fe267c7b2c456 713 SUPERFAMILY SSF48310 247 621 3.92E-71 T 22-04-2016 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS02415 2ee1d47052af0e737d5fe267c7b2c456 713 SUPERFAMILY SSF48310 664 699 3.92E-71 T 22-04-2016 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS02415 2ee1d47052af0e737d5fe267c7b2c456 713 Gene3D G3DSA:1.10.599.10 428 633 4.1E-55 T 22-04-2016 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 HRM2_RS02415 2ee1d47052af0e737d5fe267c7b2c456 713 Gene3D G3DSA:1.10.599.10 665 699 4.1E-55 T 22-04-2016 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 HRM2_RS02415 2ee1d47052af0e737d5fe267c7b2c456 713 SUPERFAMILY SSF56228 21 236 7.46E-36 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS02415 2ee1d47052af0e737d5fe267c7b2c456 713 PANTHER PTHR30038 665 702 1.5E-93 T 22-04-2016 HRM2_RS02415 2ee1d47052af0e737d5fe267c7b2c456 713 PANTHER PTHR30038 19 554 1.5E-93 T 22-04-2016 HRM2_RS02415 2ee1d47052af0e737d5fe267c7b2c456 713 PANTHER PTHR30038 571 647 1.5E-93 T 22-04-2016 HRM2_RS02415 2ee1d47052af0e737d5fe267c7b2c456 713 SMART SM00790 23 240 6.3E-30 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS02415 2ee1d47052af0e737d5fe267c7b2c456 713 Gene3D G3DSA:3.60.9.10 21 236 1.8E-49 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS03550 56988e1dea3ca136767768e865cac10f 472 PANTHER PTHR22912 4 450 3.7E-107 T 22-04-2016 HRM2_RS03550 56988e1dea3ca136767768e865cac10f 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.2E-35 T 22-04-2016 HRM2_RS03550 56988e1dea3ca136767768e865cac10f 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 304 1.2E-35 T 22-04-2016 HRM2_RS03550 56988e1dea3ca136767768e865cac10f 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 333 354 1.2E-35 T 22-04-2016 HRM2_RS03550 56988e1dea3ca136767768e865cac10f 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 171 196 1.2E-35 T 22-04-2016 HRM2_RS03550 56988e1dea3ca136767768e865cac10f 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 135 144 1.2E-35 T 22-04-2016 HRM2_RS03550 56988e1dea3ca136767768e865cac10f 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 399 414 1.2E-35 T 22-04-2016 HRM2_RS03550 56988e1dea3ca136767768e865cac10f 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 253 267 1.2E-35 T 22-04-2016 HRM2_RS03550 56988e1dea3ca136767768e865cac10f 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 1.2E-35 T 22-04-2016 HRM2_RS03550 56988e1dea3ca136767768e865cac10f 472 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 310 6.9E-35 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS03550 56988e1dea3ca136767768e865cac10f 472 SUPERFAMILY SSF55424 340 448 2.41E-20 T 22-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 HRM2_RS03550 56988e1dea3ca136767768e865cac10f 472 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 340 446 7.3E-16 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HRM2_RS03550 56988e1dea3ca136767768e865cac10f 472 Gene3D G3DSA:3.50.50.60 4 135 6.2E-27 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS03550 56988e1dea3ca136767768e865cac10f 472 PANTHER PTHR22912:SF176 4 450 3.7E-107 T 22-04-2016 HRM2_RS03550 56988e1dea3ca136767768e865cac10f 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 252 268 4.1E-14 T 22-04-2016 HRM2_RS03550 56988e1dea3ca136767768e865cac10f 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 189 4.1E-14 T 22-04-2016 HRM2_RS03550 56988e1dea3ca136767768e865cac10f 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.1E-14 T 22-04-2016 HRM2_RS03550 56988e1dea3ca136767768e865cac10f 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 4.1E-14 T 22-04-2016 HRM2_RS03550 56988e1dea3ca136767768e865cac10f 472 Gene3D G3DSA:3.30.390.30 339 450 5.9E-21 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HRM2_RS03550 56988e1dea3ca136767768e865cac10f 472 Gene3D G3DSA:3.50.50.60 136 323 9.7E-30 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS03550 56988e1dea3ca136767768e865cac10f 472 PIRSF PIRSF000350 1 435 3.0E-50 T 22-04-2016 HRM2_RS03550 56988e1dea3ca136767768e865cac10f 472 SUPERFAMILY SSF51905 5 326 2.05E-34 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS16855 ae23aa517453871ef7c6571e81d78467 309 PRINTS PR00691 Adhesin B signature 244 261 3.5E-22 T 22-04-2016 IPR006129 Adhesin B GO:0007155 HRM2_RS16855 ae23aa517453871ef7c6571e81d78467 309 PRINTS PR00691 Adhesin B signature 30 51 3.5E-22 T 22-04-2016 IPR006129 Adhesin B GO:0007155 HRM2_RS16855 ae23aa517453871ef7c6571e81d78467 309 PRINTS PR00691 Adhesin B signature 55 73 3.5E-22 T 22-04-2016 IPR006129 Adhesin B GO:0007155 HRM2_RS16855 ae23aa517453871ef7c6571e81d78467 309 PRINTS PR00691 Adhesin B signature 74 93 3.5E-22 T 22-04-2016 IPR006129 Adhesin B GO:0007155 HRM2_RS16855 ae23aa517453871ef7c6571e81d78467 309 PRINTS PR00691 Adhesin B signature 266 284 3.5E-22 T 22-04-2016 IPR006129 Adhesin B GO:0007155 HRM2_RS16855 ae23aa517453871ef7c6571e81d78467 309 PRINTS PR00691 Adhesin B signature 287 305 3.5E-22 T 22-04-2016 IPR006129 Adhesin B GO:0007155 HRM2_RS16855 ae23aa517453871ef7c6571e81d78467 309 SUPERFAMILY SSF53807 30 309 3.78E-70 T 22-04-2016 HRM2_RS16855 ae23aa517453871ef7c6571e81d78467 309 PRINTS PR00690 Adhesin family signature 61 74 6.1E-29 T 22-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 HRM2_RS16855 ae23aa517453871ef7c6571e81d78467 309 PRINTS PR00690 Adhesin family signature 185 206 6.1E-29 T 22-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 HRM2_RS16855 ae23aa517453871ef7c6571e81d78467 309 PRINTS PR00690 Adhesin family signature 74 91 6.1E-29 T 22-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 HRM2_RS16855 ae23aa517453871ef7c6571e81d78467 309 PRINTS PR00690 Adhesin family signature 30 48 6.1E-29 T 22-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 HRM2_RS16855 ae23aa517453871ef7c6571e81d78467 309 PRINTS PR00690 Adhesin family signature 274 293 6.1E-29 T 22-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 HRM2_RS16855 ae23aa517453871ef7c6571e81d78467 309 PANTHER PTHR30477 5 308 7.3E-69 T 22-04-2016 HRM2_RS16855 ae23aa517453871ef7c6571e81d78467 309 Gene3D G3DSA:3.40.50.1980 31 176 4.2E-40 T 22-04-2016 HRM2_RS16855 ae23aa517453871ef7c6571e81d78467 309 Gene3D G3DSA:3.40.50.1980 177 309 1.8E-45 T 22-04-2016 HRM2_RS16855 ae23aa517453871ef7c6571e81d78467 309 PANTHER PTHR30477:SF16 5 308 7.3E-69 T 22-04-2016 HRM2_RS16855 ae23aa517453871ef7c6571e81d78467 309 Pfam PF01297 Zinc-uptake complex component A periplasmic 33 306 7.1E-71 T 22-04-2016 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 HRM2_RS22095 368608dc8d70024a082a12746b69472e 72 Gene3D G3DSA:3.30.110.40 2 69 3.1E-16 T 22-04-2016 IPR001455 TusA-like domain HRM2_RS22095 368608dc8d70024a082a12746b69472e 72 Pfam PF01206 Sulfurtransferase TusA 4 69 1.5E-17 T 22-04-2016 IPR001455 TusA-like domain HRM2_RS22095 368608dc8d70024a082a12746b69472e 72 PANTHER PTHR33279 4 72 3.2E-12 T 22-04-2016 HRM2_RS22095 368608dc8d70024a082a12746b69472e 72 PANTHER PTHR33279:SF3 4 72 3.2E-12 T 22-04-2016 HRM2_RS22095 368608dc8d70024a082a12746b69472e 72 SUPERFAMILY SSF64307 3 69 1.44E-15 T 22-04-2016 IPR001455 TusA-like domain HRM2_RS00735 827112608b6d7627eb60886f3922dec4 253 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 231 2.5E-19 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS00735 827112608b6d7627eb60886f3922dec4 253 PANTHER PTHR30151 7 252 1.6E-65 T 22-04-2016 HRM2_RS00735 827112608b6d7627eb60886f3922dec4 253 Gene3D G3DSA:1.10.3720.10 46 243 2.3E-19 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS00735 827112608b6d7627eb60886f3922dec4 253 SUPERFAMILY SSF161098 48 233 3.01E-29 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS00735 827112608b6d7627eb60886f3922dec4 253 PANTHER PTHR30151:SF8 7 252 1.6E-65 T 22-04-2016 HRM2_RS11620 f40aaa8f58366974401643f48a13e05e 345 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 58 78 1.5E-20 T 22-04-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HRM2_RS11620 f40aaa8f58366974401643f48a13e05e 345 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 217 235 1.5E-20 T 22-04-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HRM2_RS11620 f40aaa8f58366974401643f48a13e05e 345 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 8 22 1.5E-20 T 22-04-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HRM2_RS11620 f40aaa8f58366974401643f48a13e05e 345 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 240 260 1.5E-20 T 22-04-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HRM2_RS11620 f40aaa8f58366974401643f48a13e05e 345 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 198 215 1.5E-20 T 22-04-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HRM2_RS11620 f40aaa8f58366974401643f48a13e05e 345 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 13 18 - T 22-04-2016 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 KEGG: 00860+2.1.1.11|MetaCyc: PWY-5531|MetaCyc: PWY-7159 HRM2_RS11620 f40aaa8f58366974401643f48a13e05e 345 Gene3D G3DSA:3.40.50.150 4 263 1.1E-45 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS11620 f40aaa8f58366974401643f48a13e05e 345 PANTHER PTHR13370 1 18 1.7E-53 T 22-04-2016 HRM2_RS11620 f40aaa8f58366974401643f48a13e05e 345 PANTHER PTHR13370 43 335 1.7E-53 T 22-04-2016 HRM2_RS11620 f40aaa8f58366974401643f48a13e05e 345 SUPERFAMILY SSF53335 3 261 9.5E-42 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS11620 f40aaa8f58366974401643f48a13e05e 345 Pfam PF01555 DNA methylase 9 253 1.4E-35 T 22-04-2016 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 HRM2_RS11620 f40aaa8f58366974401643f48a13e05e 345 PANTHER PTHR13370:SF4 1 18 1.7E-53 T 22-04-2016 HRM2_RS11620 f40aaa8f58366974401643f48a13e05e 345 PANTHER PTHR13370:SF4 43 335 1.7E-53 T 22-04-2016 HRM2_RS20890 39dc9608a0e5aa10eca115404213ab4a 441 SUPERFAMILY SSF56014 323 440 8.6E-64 T 22-04-2016 HRM2_RS20890 39dc9608a0e5aa10eca115404213ab4a 441 SUPERFAMILY SSF56014 168 242 8.6E-64 T 22-04-2016 HRM2_RS20890 39dc9608a0e5aa10eca115404213ab4a 441 Gene3D G3DSA:3.30.70.20 283 317 3.2E-5 T 22-04-2016 HRM2_RS20890 39dc9608a0e5aa10eca115404213ab4a 441 PANTHER PTHR11493:SF50 320 424 3.7E-93 T 22-04-2016 HRM2_RS20890 39dc9608a0e5aa10eca115404213ab4a 441 PANTHER PTHR11493:SF50 80 239 3.7E-93 T 22-04-2016 HRM2_RS20890 39dc9608a0e5aa10eca115404213ab4a 441 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 167 400 4.3E-39 T 22-04-2016 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 HRM2_RS20890 39dc9608a0e5aa10eca115404213ab4a 441 TIGRFAM TIGR02064 dsrA: sulfite reductase, dissimilatory-type alpha subunit 9 433 5.7E-180 T 22-04-2016 IPR011806 Sulphite reductase, dissimilatory-type alpha subunit GO:0018551|GO:0020037|GO:0051539|GO:0055114 HRM2_RS20890 39dc9608a0e5aa10eca115404213ab4a 441 SUPERFAMILY SSF55124 4 168 7.41E-74 T 22-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 HRM2_RS20890 39dc9608a0e5aa10eca115404213ab4a 441 PANTHER PTHR11493 320 424 3.7E-93 T 22-04-2016 HRM2_RS20890 39dc9608a0e5aa10eca115404213ab4a 441 PANTHER PTHR11493 80 239 3.7E-93 T 22-04-2016 HRM2_RS20890 39dc9608a0e5aa10eca115404213ab4a 441 SUPERFAMILY SSF54862 228 320 1.86E-18 T 22-04-2016 HRM2_RS20890 39dc9608a0e5aa10eca115404213ab4a 441 Gene3D G3DSA:3.30.413.10 170 242 1.3E-20 T 22-04-2016 HRM2_RS20890 39dc9608a0e5aa10eca115404213ab4a 441 Gene3D G3DSA:3.30.413.10 326 398 1.3E-20 T 22-04-2016 HRM2_RS22785 4bbaecf493d46b5955687dfd3359ddb7 154 SUPERFAMILY SSF53254 1 142 3.93E-16 T 22-04-2016 IPR029033 Histidine phosphatase superfamily HRM2_RS22785 4bbaecf493d46b5955687dfd3359ddb7 154 Gene3D G3DSA:3.40.50.1240 1 146 1.1E-19 T 22-04-2016 IPR029033 Histidine phosphatase superfamily HRM2_RS22785 4bbaecf493d46b5955687dfd3359ddb7 154 TIGRFAM TIGR00249 sixA: phosphohistidine phosphatase SixA 1 148 5.4E-28 T 22-04-2016 IPR004449 Phosphohistidine phosphatase SixA GO:0005737|GO:0006464|GO:0008969 KEGG: 00051+3.1.3.-|KEGG: 00332+3.1.3.-|KEGG: 00565+3.1.3.-|KEGG: 00600+3.1.3.-|KEGG: 00730+3.1.3.-|KEGG: 00740+3.1.3.-|KEGG: 00760+3.1.3.- HRM2_RS22785 4bbaecf493d46b5955687dfd3359ddb7 154 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 69 1.1E-5 T 22-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 HRM2_RS18555 769e73541a33e5f8a50f1e5de8bb0eea 811 SMART SM00448 7 122 1.4E-8 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18555 769e73541a33e5f8a50f1e5de8bb0eea 811 PANTHER PTHR38032 286 751 5.1E-45 T 22-04-2016 HRM2_RS18555 769e73541a33e5f8a50f1e5de8bb0eea 811 Pfam PF03961 Protein of unknown function (DUF342) 293 684 3.1E-76 T 22-04-2016 IPR005646 Protein of unknown function DUF342 HRM2_RS18555 769e73541a33e5f8a50f1e5de8bb0eea 811 Pfam PF00072 Response regulator receiver domain 9 122 1.4E-6 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18555 769e73541a33e5f8a50f1e5de8bb0eea 811 SUPERFAMILY SSF52172 7 148 1.71E-14 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS18555 769e73541a33e5f8a50f1e5de8bb0eea 811 Gene3D G3DSA:3.40.50.2300 6 131 2.4E-14 T 22-04-2016 HRM2_RS01020 dd7c1619c6bf44f9e1961ec159eec5bb 109 SUPERFAMILY SSF52091 2 105 1.9E-23 T 22-04-2016 IPR002645 STAS domain HRM2_RS01020 dd7c1619c6bf44f9e1961ec159eec5bb 109 Gene3D G3DSA:3.30.750.24 2 105 2.1E-24 T 22-04-2016 IPR002645 STAS domain HRM2_RS01020 dd7c1619c6bf44f9e1961ec159eec5bb 109 PANTHER PTHR33495 1 105 1.9E-20 T 22-04-2016 HRM2_RS01020 dd7c1619c6bf44f9e1961ec159eec5bb 109 Pfam PF01740 STAS domain 4 105 1.2E-15 T 22-04-2016 IPR002645 STAS domain HRM2_RS01020 dd7c1619c6bf44f9e1961ec159eec5bb 109 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 2 104 1.8E-22 T 22-04-2016 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 HRM2_RS06750 50b6f73ab651e6eed806f2e1044c5e4a 333 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 312 2.6E-124 T 22-04-2016 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HRM2_RS06750 50b6f73ab651e6eed806f2e1044c5e4a 333 SUPERFAMILY SSF53067 101 308 6.22E-39 T 22-04-2016 HRM2_RS06750 50b6f73ab651e6eed806f2e1044c5e4a 333 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 264 273 7.5E-46 T 22-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HRM2_RS06750 50b6f73ab651e6eed806f2e1044c5e4a 333 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 7.5E-46 T 22-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HRM2_RS06750 50b6f73ab651e6eed806f2e1044c5e4a 333 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 154 175 7.5E-46 T 22-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HRM2_RS06750 50b6f73ab651e6eed806f2e1044c5e4a 333 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 7.5E-46 T 22-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HRM2_RS06750 50b6f73ab651e6eed806f2e1044c5e4a 333 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 131 143 7.5E-46 T 22-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HRM2_RS06750 50b6f73ab651e6eed806f2e1044c5e4a 333 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 7.5E-46 T 22-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HRM2_RS06750 50b6f73ab651e6eed806f2e1044c5e4a 333 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 332 57.67 T 22-04-2016 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HRM2_RS06750 50b6f73ab651e6eed806f2e1044c5e4a 333 SUPERFAMILY SSF53067 2 122 1.1E-29 T 22-04-2016 HRM2_RS06750 50b6f73ab651e6eed806f2e1044c5e4a 333 Pfam PF00814 Glycoprotease family 23 307 5.3E-92 T 22-04-2016 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HRM2_RS06750 50b6f73ab651e6eed806f2e1044c5e4a 333 Gene3D G3DSA:3.30.420.40 1 159 8.7E-46 T 22-04-2016 HRM2_RS06750 50b6f73ab651e6eed806f2e1044c5e4a 333 PANTHER PTHR11735:SF6 1 317 1.1E-135 T 22-04-2016 HRM2_RS06750 50b6f73ab651e6eed806f2e1044c5e4a 333 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 307 1.7E-99 T 22-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HRM2_RS06750 50b6f73ab651e6eed806f2e1044c5e4a 333 PANTHER PTHR11735 1 317 1.1E-135 T 22-04-2016 HRM2_RS06525 71c11921faa1a1e5a5f627144045da0a 582 SUPERFAMILY SSF69279 17 188 1.13E-13 T 22-04-2016 HRM2_RS06525 71c11921faa1a1e5a5f627144045da0a 582 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 32 494 1.7E-73 T 22-04-2016 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein HRM2_RS06525 71c11921faa1a1e5a5f627144045da0a 582 Gene3D G3DSA:2.40.50.230 378 452 1.5E-14 T 22-04-2016 IPR006531 Gp5 N-terminal HRM2_RS06525 71c11921faa1a1e5a5f627144045da0a 582 SUPERFAMILY SSF69255 372 452 8.11E-19 T 22-04-2016 HRM2_RS02890 fcd275ace3f9e2ca4077bb9a0ed58e06 322 PANTHER PTHR23131 144 319 5.6E-46 T 22-04-2016 HRM2_RS02890 fcd275ace3f9e2ca4077bb9a0ed58e06 322 PANTHER PTHR23131 12 124 5.6E-46 T 22-04-2016 HRM2_RS02890 fcd275ace3f9e2ca4077bb9a0ed58e06 322 PANTHER PTHR23131:SF4 144 319 5.6E-46 T 22-04-2016 HRM2_RS02890 fcd275ace3f9e2ca4077bb9a0ed58e06 322 PANTHER PTHR23131:SF4 12 124 5.6E-46 T 22-04-2016 HRM2_RS02890 fcd275ace3f9e2ca4077bb9a0ed58e06 322 SMART SM00849 23 228 1.3E-25 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS02890 fcd275ace3f9e2ca4077bb9a0ed58e06 322 SUPERFAMILY SSF56281 2 309 8.12E-55 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS02890 fcd275ace3f9e2ca4077bb9a0ed58e06 322 Gene3D G3DSA:3.60.15.10 136 257 2.5E-43 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS02890 fcd275ace3f9e2ca4077bb9a0ed58e06 322 Gene3D G3DSA:3.60.15.10 2 103 2.5E-43 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS02890 fcd275ace3f9e2ca4077bb9a0ed58e06 322 Pfam PF00753 Metallo-beta-lactamase superfamily 25 228 5.8E-17 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS15220 6dc5699c6795a1163ff2b710f3a40404 505 SMART SM00387 388 500 6.3E-37 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS15220 6dc5699c6795a1163ff2b710f3a40404 505 Pfam PF00512 His Kinase A (phospho-acceptor) domain 274 341 2.8E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS15220 6dc5699c6795a1163ff2b710f3a40404 505 Pfam PF00989 PAS fold 151 264 7.6E-7 T 22-04-2016 IPR013767 PAS fold GO:0006355 HRM2_RS15220 6dc5699c6795a1163ff2b710f3a40404 505 SMART SM00448 7 118 2.9E-35 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS15220 6dc5699c6795a1163ff2b710f3a40404 505 Gene3D G3DSA:1.10.287.130 266 337 3.5E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS15220 6dc5699c6795a1163ff2b710f3a40404 505 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 453 1.8E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS15220 6dc5699c6795a1163ff2b710f3a40404 505 PRINTS PR00344 Bacterial sensor protein C-terminal signature 484 497 1.8E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS15220 6dc5699c6795a1163ff2b710f3a40404 505 PRINTS PR00344 Bacterial sensor protein C-terminal signature 460 478 1.8E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS15220 6dc5699c6795a1163ff2b710f3a40404 505 PRINTS PR00344 Bacterial sensor protein C-terminal signature 425 439 1.8E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS15220 6dc5699c6795a1163ff2b710f3a40404 505 Pfam PF00072 Response regulator receiver domain 9 118 1.8E-27 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS15220 6dc5699c6795a1163ff2b710f3a40404 505 PANTHER PTHR24423 3 10 5.3E-80 T 22-04-2016 HRM2_RS15220 6dc5699c6795a1163ff2b710f3a40404 505 PANTHER PTHR24423 148 502 5.3E-80 T 22-04-2016 HRM2_RS15220 6dc5699c6795a1163ff2b710f3a40404 505 Gene3D G3DSA:3.30.450.20 146 264 8.6E-10 T 22-04-2016 HRM2_RS15220 6dc5699c6795a1163ff2b710f3a40404 505 SUPERFAMILY SSF55785 137 258 5.9E-9 T 22-04-2016 IPR000014 PAS domain HRM2_RS15220 6dc5699c6795a1163ff2b710f3a40404 505 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 388 499 1.8E-23 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS15220 6dc5699c6795a1163ff2b710f3a40404 505 SUPERFAMILY SSF47384 264 341 8.24E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS15220 6dc5699c6795a1163ff2b710f3a40404 505 SUPERFAMILY SSF52172 5 145 3.42E-40 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS15220 6dc5699c6795a1163ff2b710f3a40404 505 Gene3D G3DSA:3.40.50.2300 7 145 1.1E-36 T 22-04-2016 HRM2_RS15220 6dc5699c6795a1163ff2b710f3a40404 505 SUPERFAMILY SSF55874 331 499 1.27E-48 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS15220 6dc5699c6795a1163ff2b710f3a40404 505 Gene3D G3DSA:3.30.565.10 347 499 3.1E-46 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS15220 6dc5699c6795a1163ff2b710f3a40404 505 SMART SM00091 150 221 7.5E-4 T 22-04-2016 IPR000014 PAS domain HRM2_RS15220 6dc5699c6795a1163ff2b710f3a40404 505 SMART SM00388 273 341 6.1E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS00370 36d5aeca19bc68f896376aa435f953b7 719 PANTHER PTHR33989 28 450 5.1E-99 T 22-04-2016 HRM2_RS00370 36d5aeca19bc68f896376aa435f953b7 719 SMART SM00052 463 709 3.4E-89 T 22-04-2016 IPR001633 EAL domain HRM2_RS00370 36d5aeca19bc68f896376aa435f953b7 719 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 21 425 7.5E-76 T 22-04-2016 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 HRM2_RS00370 36d5aeca19bc68f896376aa435f953b7 719 PANTHER PTHR33989:SF4 28 450 5.1E-99 T 22-04-2016 HRM2_RS00370 36d5aeca19bc68f896376aa435f953b7 719 Pfam PF00563 EAL domain 470 704 2.6E-66 T 22-04-2016 IPR001633 EAL domain HRM2_RS00370 36d5aeca19bc68f896376aa435f953b7 719 Gene3D G3DSA:3.20.20.450 467 715 9.7E-81 T 22-04-2016 IPR001633 EAL domain HRM2_RS00370 36d5aeca19bc68f896376aa435f953b7 719 SUPERFAMILY SSF141868 477 715 7.32E-75 T 22-04-2016 IPR001633 EAL domain HRM2_RS00370 36d5aeca19bc68f896376aa435f953b7 719 Pfam PF02378 Phosphotransferase system, EIIC 33 358 1.3E-29 T 22-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 HRM2_RS10420 767119f81343fc3e1e16d7cd957507ca 469 Gene3D G3DSA:3.40.50.300 16 214 1.3E-12 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10420 767119f81343fc3e1e16d7cd957507ca 469 Pfam PF00005 ABC transporter 267 419 1.4E-18 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS10420 767119f81343fc3e1e16d7cd957507ca 469 SUPERFAMILY SSF52540 251 464 2.44E-37 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10420 767119f81343fc3e1e16d7cd957507ca 469 SMART SM00382 275 468 6.9E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS10420 767119f81343fc3e1e16d7cd957507ca 469 PANTHER PTHR24220 20 374 1.1E-46 T 22-04-2016 HRM2_RS10420 767119f81343fc3e1e16d7cd957507ca 469 SUPERFAMILY SSF52540 16 213 1.15E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10420 767119f81343fc3e1e16d7cd957507ca 469 PANTHER PTHR24220:SF557 20 374 1.1E-46 T 22-04-2016 HRM2_RS10420 767119f81343fc3e1e16d7cd957507ca 469 Gene3D G3DSA:3.40.50.300 246 460 5.9E-37 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18455 f712fc28e050e19c2d87e5e56cf635d5 158 SMART SM00344 1 108 5.0E-30 T 22-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 HRM2_RS18455 f712fc28e050e19c2d87e5e56cf635d5 158 Gene3D G3DSA:3.30.70.920 53 148 7.9E-21 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain HRM2_RS18455 f712fc28e050e19c2d87e5e56cf635d5 158 SUPERFAMILY SSF46785 1 58 1.99E-16 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS18455 f712fc28e050e19c2d87e5e56cf635d5 158 Pfam PF01037 Lrp/AsnC ligand binding domain 71 139 2.0E-12 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain HRM2_RS18455 f712fc28e050e19c2d87e5e56cf635d5 158 SUPERFAMILY SSF54909 63 147 2.28E-13 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel HRM2_RS18455 f712fc28e050e19c2d87e5e56cf635d5 158 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 8.6E-17 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 HRM2_RS18455 f712fc28e050e19c2d87e5e56cf635d5 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 2.3E-15 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 HRM2_RS18455 f712fc28e050e19c2d87e5e56cf635d5 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 2.3E-15 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 HRM2_RS18455 f712fc28e050e19c2d87e5e56cf635d5 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 2.3E-15 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 HRM2_RS18455 f712fc28e050e19c2d87e5e56cf635d5 158 PANTHER PTHR30154 1 148 2.3E-37 T 22-04-2016 HRM2_RS18455 f712fc28e050e19c2d87e5e56cf635d5 158 Gene3D G3DSA:1.10.10.10 1 51 1.1E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS05730 61b52f7fe73cf8b08ce7430d7578a88a 78 PANTHER PTHR35177 1 78 1.2E-24 T 22-04-2016 HRM2_RS05730 61b52f7fe73cf8b08ce7430d7578a88a 78 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 74 1.9E-28 T 22-04-2016 IPR001109 Hydrogenase expression/formation protein, HupF/HypC HRM2_RS05730 61b52f7fe73cf8b08ce7430d7578a88a 78 Pfam PF01455 HupF/HypC family 1 63 1.8E-28 T 22-04-2016 IPR001109 Hydrogenase expression/formation protein, HupF/HypC HRM2_RS05730 61b52f7fe73cf8b08ce7430d7578a88a 78 PANTHER PTHR35177:SF2 1 78 1.2E-24 T 22-04-2016 HRM2_RS05730 61b52f7fe73cf8b08ce7430d7578a88a 78 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 22-04-2016 IPR019812 Hydrogenase assembly chaperone, conserved site HRM2_RS05730 61b52f7fe73cf8b08ce7430d7578a88a 78 SUPERFAMILY SSF159127 1 73 1.44E-26 T 22-04-2016 HRM2_RS05730 61b52f7fe73cf8b08ce7430d7578a88a 78 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 17 33 2.5E-16 T 22-04-2016 IPR001109 Hydrogenase expression/formation protein, HupF/HypC HRM2_RS05730 61b52f7fe73cf8b08ce7430d7578a88a 78 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 2.5E-16 T 22-04-2016 IPR001109 Hydrogenase expression/formation protein, HupF/HypC HRM2_RS05730 61b52f7fe73cf8b08ce7430d7578a88a 78 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 56 68 2.5E-16 T 22-04-2016 IPR001109 Hydrogenase expression/formation protein, HupF/HypC HRM2_RS05730 61b52f7fe73cf8b08ce7430d7578a88a 78 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 38 54 2.5E-16 T 22-04-2016 IPR001109 Hydrogenase expression/formation protein, HupF/HypC HRM2_RS00840 9628e4892b7b418ce63763c96c144f6b 462 PANTHER PTHR30425 158 462 2.5E-99 T 22-04-2016 HRM2_RS00840 9628e4892b7b418ce63763c96c144f6b 462 Gene3D G3DSA:1.10.3720.10 208 461 1.4E-37 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS00840 9628e4892b7b418ce63763c96c144f6b 462 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 249 458 1.0E-19 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS00840 9628e4892b7b418ce63763c96c144f6b 462 SUPERFAMILY SSF161098 168 453 1.31E-30 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS00840 9628e4892b7b418ce63763c96c144f6b 462 PANTHER PTHR30425:SF3 158 462 2.5E-99 T 22-04-2016 HRM2_RS00840 9628e4892b7b418ce63763c96c144f6b 462 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 164 457 1.1E-85 T 22-04-2016 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 HRM2_RS00840 9628e4892b7b418ce63763c96c144f6b 462 Pfam PF12501 Phosphate ATP-binding cassette transporter 7 180 1.0E-35 T 22-04-2016 IPR022182 ABC transporter phosphate permease PstC, N-terminal domain GO:0006817 HRM2_RS01495 308802ca94ef1ca1ce88b32a37850d3b 300 SUPERFAMILY SSF51735 5 185 2.37E-41 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS01495 308802ca94ef1ca1ce88b32a37850d3b 300 Gene3D G3DSA:3.40.50.720 4 191 6.3E-42 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS01495 308802ca94ef1ca1ce88b32a37850d3b 300 PANTHER PTHR23309 1 290 1.2E-72 T 22-04-2016 HRM2_RS01495 308802ca94ef1ca1ce88b32a37850d3b 300 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 190 287 1.9E-17 T 22-04-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 HRM2_RS01495 308802ca94ef1ca1ce88b32a37850d3b 300 PIRSF PIRSF000105 1 298 1.5E-71 T 22-04-2016 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 HRM2_RS01495 308802ca94ef1ca1ce88b32a37850d3b 300 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 9 184 2.9E-45 T 22-04-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 HRM2_RS01495 308802ca94ef1ca1ce88b32a37850d3b 300 Gene3D G3DSA:1.10.1040.10 192 288 2.7E-18 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HRM2_RS01495 308802ca94ef1ca1ce88b32a37850d3b 300 SUPERFAMILY SSF48179 190 289 4.85E-18 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HRM2_RS14040 4f2d01a2831dc50ac1a71aea4a7add6a 154 SUPERFAMILY SSF109770 29 148 1.31E-6 T 22-04-2016 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 HRM2_RS14040 4f2d01a2831dc50ac1a71aea4a7add6a 154 Gene3D G3DSA:1.20.120.400 29 153 4.0E-30 T 22-04-2016 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 HRM2_RS14040 4f2d01a2831dc50ac1a71aea4a7add6a 154 Pfam PF09055 Nickel-containing superoxide dismutase 26 153 6.9E-37 T 22-04-2016 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 HRM2_RS18860 e21f34cea61cb57a1b7e546da51c6d3e 536 PANTHER PTHR10283 94 520 4.9E-53 T 22-04-2016 HRM2_RS18860 e21f34cea61cb57a1b7e546da51c6d3e 536 PANTHER PTHR10283 13 53 4.9E-53 T 22-04-2016 HRM2_RS18860 e21f34cea61cb57a1b7e546da51c6d3e 536 Pfam PF00939 Sodium:sulfate symporter transmembrane region 93 494 7.8E-34 T 22-04-2016 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 HRM2_RS04450 1326577f4382796314b064f311c8ebeb 536 PANTHER PTHR11918:SF64 88 408 4.2E-53 T 22-04-2016 HRM2_RS04450 1326577f4382796314b064f311c8ebeb 536 SMART SM00729 215 430 3.9E-5 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS04450 1326577f4382796314b064f311c8ebeb 536 SUPERFAMILY SSF102114 194 425 2.88E-20 T 22-04-2016 HRM2_RS04450 1326577f4382796314b064f311c8ebeb 536 SUPERFAMILY SSF52242 73 151 1.28E-7 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS04450 1326577f4382796314b064f311c8ebeb 536 Pfam PF02310 B12 binding domain 10 157 4.4E-19 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS04450 1326577f4382796314b064f311c8ebeb 536 Gene3D G3DSA:3.80.30.20 216 406 6.5E-18 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe HRM2_RS04450 1326577f4382796314b064f311c8ebeb 536 PANTHER PTHR11918 88 408 4.2E-53 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein HRM2_RS04710 fd47a8f93f354e47ec6e50e95a244dad 285 Gene3D G3DSA:3.40.50.10410 90 183 4.8E-32 T 22-04-2016 IPR023215 Nitrophenylphosphatase-like domain HRM2_RS04710 fd47a8f93f354e47ec6e50e95a244dad 285 Pfam PF13344 Haloacid dehalogenase-like hydrolase 11 112 5.9E-23 T 22-04-2016 IPR006357 HAD-superfamily hydrolase, subfamily IIA HRM2_RS04710 fd47a8f93f354e47ec6e50e95a244dad 285 Gene3D G3DSA:3.40.50.1000 9 84 2.9E-39 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS04710 fd47a8f93f354e47ec6e50e95a244dad 285 Gene3D G3DSA:3.40.50.1000 184 257 2.9E-39 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS04710 fd47a8f93f354e47ec6e50e95a244dad 285 SUPERFAMILY SSF56784 9 257 2.59E-65 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS04710 fd47a8f93f354e47ec6e50e95a244dad 285 PIRSF PIRSF000915 3 261 1.3E-53 T 22-04-2016 IPR006357 HAD-superfamily hydrolase, subfamily IIA HRM2_RS04710 fd47a8f93f354e47ec6e50e95a244dad 285 PANTHER PTHR19288:SF40 1 268 1.4E-101 T 22-04-2016 HRM2_RS04710 fd47a8f93f354e47ec6e50e95a244dad 285 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 11 233 3.2E-48 T 22-04-2016 IPR006357 HAD-superfamily hydrolase, subfamily IIA HRM2_RS04710 fd47a8f93f354e47ec6e50e95a244dad 285 Pfam PF13242 HAD-hyrolase-like 184 256 2.9E-22 T 22-04-2016 HRM2_RS04710 fd47a8f93f354e47ec6e50e95a244dad 285 PANTHER PTHR19288 1 268 1.4E-101 T 22-04-2016 HRM2_RS03140 d2dc50dee0a6ebaaa50dd3947e027c8f 285 Gene3D G3DSA:3.40.50.720 4 75 9.8E-5 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS03140 d2dc50dee0a6ebaaa50dd3947e027c8f 285 PANTHER PTHR10742:SF263 1 182 1.2E-17 T 22-04-2016 HRM2_RS03140 d2dc50dee0a6ebaaa50dd3947e027c8f 285 PANTHER PTHR10742 1 182 1.2E-17 T 22-04-2016 HRM2_RS03140 d2dc50dee0a6ebaaa50dd3947e027c8f 285 SUPERFAMILY SSF51905 6 229 2.33E-7 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS04965 87912c8282eb6db601597725b1b516d4 394 SUPERFAMILY SSF103473 4 383 7.59E-57 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS04965 87912c8282eb6db601597725b1b516d4 394 Gene3D G3DSA:1.20.1250.20 203 385 3.4E-21 T 22-04-2016 HRM2_RS04965 87912c8282eb6db601597725b1b516d4 394 Gene3D G3DSA:1.20.1250.20 3 184 2.9E-29 T 22-04-2016 HRM2_RS04965 87912c8282eb6db601597725b1b516d4 394 Pfam PF07690 Major Facilitator Superfamily 211 392 4.9E-17 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS04965 87912c8282eb6db601597725b1b516d4 394 Pfam PF07690 Major Facilitator Superfamily 12 191 6.5E-28 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS04965 87912c8282eb6db601597725b1b516d4 394 PANTHER PTHR23501 7 352 2.3E-28 T 22-04-2016 HRM2_RS17935 c7dd9b1edcac6a9d33906ab5cfed591d 127 SUPERFAMILY SSF54736 56 127 1.1E-24 T 22-04-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like HRM2_RS17935 c7dd9b1edcac6a9d33906ab5cfed591d 127 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 61 127 9.4E-30 T 22-04-2016 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 HRM2_RS17935 c7dd9b1edcac6a9d33906ab5cfed591d 127 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 127 7.5E-52 T 22-04-2016 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17935 c7dd9b1edcac6a9d33906ab5cfed591d 127 Gene3D G3DSA:3.30.1390.10 55 127 1.7E-33 T 22-04-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like HRM2_RS17935 c7dd9b1edcac6a9d33906ab5cfed591d 127 SUPERFAMILY SSF48300 5 63 1.57E-17 T 22-04-2016 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17935 c7dd9b1edcac6a9d33906ab5cfed591d 127 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 53 1.0E-21 T 22-04-2016 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17935 c7dd9b1edcac6a9d33906ab5cfed591d 127 Gene3D G3DSA:1.20.5.710 4 53 2.2E-22 T 22-04-2016 HRM2_RS17935 c7dd9b1edcac6a9d33906ab5cfed591d 127 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 63 127 5.0E-19 T 22-04-2016 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 HRM2_RS17935 c7dd9b1edcac6a9d33906ab5cfed591d 127 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 3 127 25.476 T 22-04-2016 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS15335 62e2ed92c102056e53a051c871503f3a 457 Pfam PF13379 NMT1-like family 148 381 1.4E-24 T 22-04-2016 HRM2_RS15335 62e2ed92c102056e53a051c871503f3a 457 SMART SM00448 7 121 3.5E-33 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS15335 62e2ed92c102056e53a051c871503f3a 457 SUPERFAMILY SSF53850 185 380 1.18E-13 T 22-04-2016 HRM2_RS15335 62e2ed92c102056e53a051c871503f3a 457 PANTHER PTHR26402 7 125 5.6E-34 T 22-04-2016 HRM2_RS15335 62e2ed92c102056e53a051c871503f3a 457 Pfam PF00072 Response regulator receiver domain 9 121 1.4E-24 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS15335 62e2ed92c102056e53a051c871503f3a 457 SUPERFAMILY SSF52172 6 126 2.13E-34 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS15335 62e2ed92c102056e53a051c871503f3a 457 Gene3D G3DSA:3.40.50.2300 5 131 1.4E-34 T 22-04-2016 HRM2_RS21160 c8bd797c6d42006af77bd58baf5fc015 325 Gene3D G3DSA:3.40.190.10 113 236 1.4E-20 T 22-04-2016 HRM2_RS21160 c8bd797c6d42006af77bd58baf5fc015 325 PANTHER PTHR30024 34 294 1.2E-29 T 22-04-2016 HRM2_RS21160 c8bd797c6d42006af77bd58baf5fc015 325 SUPERFAMILY SSF53850 27 289 1.51E-36 T 22-04-2016 HRM2_RS21160 c8bd797c6d42006af77bd58baf5fc015 325 PANTHER PTHR30024:SF5 34 294 1.2E-29 T 22-04-2016 HRM2_RS21160 c8bd797c6d42006af77bd58baf5fc015 325 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 1 289 2.4E-37 T 22-04-2016 IPR011852 TRAP transporter solute receptor, TAXI family HRM2_RS21160 c8bd797c6d42006af77bd58baf5fc015 325 Gene3D G3DSA:3.40.190.10 27 104 1.1E-13 T 22-04-2016 HRM2_RS21160 c8bd797c6d42006af77bd58baf5fc015 325 Gene3D G3DSA:3.40.190.10 237 284 1.1E-13 T 22-04-2016 HRM2_RS21160 c8bd797c6d42006af77bd58baf5fc015 325 Pfam PF16868 NMT1-like family 29 285 1.1E-32 T 22-04-2016 IPR011852 TRAP transporter solute receptor, TAXI family HRM2_RS06125 fd2165329e4435dd2ff927c4ccf7b74d 239 SUPERFAMILY SSF53328 6 66 1.11E-42 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HRM2_RS06125 fd2165329e4435dd2ff927c4ccf7b74d 239 SUPERFAMILY SSF53328 109 235 1.11E-42 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HRM2_RS06125 fd2165329e4435dd2ff927c4ccf7b74d 239 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 6 236 26.56 T 22-04-2016 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|UniPathway: UPA00074 HRM2_RS06125 fd2165329e4435dd2ff927c4ccf7b74d 239 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 8 235 7.6E-49 T 22-04-2016 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|UniPathway: UPA00074 HRM2_RS06125 fd2165329e4435dd2ff927c4ccf7b74d 239 Pfam PF00551 Formyl transferase 10 229 6.4E-40 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HRM2_RS06125 fd2165329e4435dd2ff927c4ccf7b74d 239 PANTHER PTHR10520 110 239 4.3E-59 T 22-04-2016 HRM2_RS06125 fd2165329e4435dd2ff927c4ccf7b74d 239 PANTHER PTHR10520 10 75 4.3E-59 T 22-04-2016 HRM2_RS06125 fd2165329e4435dd2ff927c4ccf7b74d 239 Gene3D G3DSA:3.40.50.170 6 67 6.6E-56 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HRM2_RS06125 fd2165329e4435dd2ff927c4ccf7b74d 239 Gene3D G3DSA:3.40.50.170 110 236 6.6E-56 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HRM2_RS03235 a2d1e7c845bea69c06112ea0de7995d8 557 PRINTS PR01900 YidC translocation/secretion protein signature 345 361 4.0E-18 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 HRM2_RS03235 a2d1e7c845bea69c06112ea0de7995d8 557 PRINTS PR01900 YidC translocation/secretion protein signature 509 533 4.0E-18 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 HRM2_RS03235 a2d1e7c845bea69c06112ea0de7995d8 557 PRINTS PR01900 YidC translocation/secretion protein signature 490 505 4.0E-18 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 HRM2_RS03235 a2d1e7c845bea69c06112ea0de7995d8 557 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 5 556 20.962 T 22-04-2016 IPR019998 Membrane insertase YidC GO:0016021|GO:0051205 HRM2_RS03235 a2d1e7c845bea69c06112ea0de7995d8 557 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 4 357 7.6E-68 T 22-04-2016 IPR028053 Membrane insertase YidC, N-terminal HRM2_RS03235 a2d1e7c845bea69c06112ea0de7995d8 557 PRINTS PR00701 60kDa inner membrane protein signature 177 197 4.0E-23 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 HRM2_RS03235 a2d1e7c845bea69c06112ea0de7995d8 557 PRINTS PR00701 60kDa inner membrane protein signature 89 110 4.0E-23 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 HRM2_RS03235 a2d1e7c845bea69c06112ea0de7995d8 557 PRINTS PR00701 60kDa inner membrane protein signature 258 273 4.0E-23 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 HRM2_RS03235 a2d1e7c845bea69c06112ea0de7995d8 557 PRINTS PR00701 60kDa inner membrane protein signature 3 24 4.0E-23 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 HRM2_RS03235 a2d1e7c845bea69c06112ea0de7995d8 557 PRINTS PR00701 60kDa inner membrane protein signature 484 506 4.0E-23 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 HRM2_RS03235 a2d1e7c845bea69c06112ea0de7995d8 557 PRINTS PR00701 60kDa inner membrane protein signature 520 543 4.0E-23 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 HRM2_RS03235 a2d1e7c845bea69c06112ea0de7995d8 557 Pfam PF02096 60Kd inner membrane protein 360 554 2.0E-64 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 HRM2_RS03235 a2d1e7c845bea69c06112ea0de7995d8 557 PANTHER PTHR12428 337 469 2.5E-70 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 HRM2_RS03235 a2d1e7c845bea69c06112ea0de7995d8 557 PANTHER PTHR12428 486 555 2.5E-70 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 HRM2_RS03235 a2d1e7c845bea69c06112ea0de7995d8 557 PANTHER PTHR12428:SF14 337 469 2.5E-70 T 22-04-2016 HRM2_RS03235 a2d1e7c845bea69c06112ea0de7995d8 557 PANTHER PTHR12428:SF14 486 555 2.5E-70 T 22-04-2016 HRM2_RS03235 a2d1e7c845bea69c06112ea0de7995d8 557 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 359 554 2.8E-71 T 22-04-2016 IPR028055 Membrane insertase YidC/Oxa1, C-terminal HRM2_RS03235 a2d1e7c845bea69c06112ea0de7995d8 557 Pfam PF14849 YidC periplasmic domain 84 345 3.4E-48 T 22-04-2016 IPR028053 Membrane insertase YidC, N-terminal HRM2_RS17055 753add4c795b28d29f79ecb9d9d8d7ec 193 ProSitePatterns PS00398 Site-specific recombinases signature 2. 58 70 - T 22-04-2016 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 HRM2_RS17055 753add4c795b28d29f79ecb9d9d8d7ec 193 PANTHER PTHR30461:SF9 1 184 9.7E-46 T 22-04-2016 HRM2_RS17055 753add4c795b28d29f79ecb9d9d8d7ec 193 Pfam PF00239 Resolvase, N terminal domain 4 139 2.6E-36 T 22-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HRM2_RS17055 753add4c795b28d29f79ecb9d9d8d7ec 193 SUPERFAMILY SSF46689 141 183 4.1E-6 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS17055 753add4c795b28d29f79ecb9d9d8d7ec 193 SUPERFAMILY SSF53041 1 139 3.27E-36 T 22-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HRM2_RS17055 753add4c795b28d29f79ecb9d9d8d7ec 193 Gene3D G3DSA:3.40.50.1390 3 122 6.9E-31 T 22-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HRM2_RS17055 753add4c795b28d29f79ecb9d9d8d7ec 193 SMART SM00857 3 139 3.0E-42 T 22-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HRM2_RS17055 753add4c795b28d29f79ecb9d9d8d7ec 193 PANTHER PTHR30461 1 184 9.7E-46 T 22-04-2016 HRM2_RS17055 753add4c795b28d29f79ecb9d9d8d7ec 193 Gene3D G3DSA:1.10.10.60 141 182 1.9E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS23230 b8943777eb06f359db50d6b7ebe81510 225 SMART SM00345 13 71 2.3E-20 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS23230 b8943777eb06f359db50d6b7ebe81510 225 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 71 2.5E-18 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS23230 b8943777eb06f359db50d6b7ebe81510 225 PANTHER PTHR11751 16 98 4.6E-24 T 22-04-2016 HRM2_RS23230 b8943777eb06f359db50d6b7ebe81510 225 Gene3D G3DSA:1.10.10.10 7 72 1.8E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS23230 b8943777eb06f359db50d6b7ebe81510 225 SUPERFAMILY SSF48008 77 216 7.85E-16 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS23230 b8943777eb06f359db50d6b7ebe81510 225 Pfam PF07729 FCD domain 136 208 7.6E-9 T 22-04-2016 IPR011711 GntR, C-terminal HRM2_RS23230 b8943777eb06f359db50d6b7ebe81510 225 Gene3D G3DSA:1.20.120.530 74 220 1.4E-19 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS23230 b8943777eb06f359db50d6b7ebe81510 225 SUPERFAMILY SSF46785 8 75 4.57E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS17970 396d4d24a86a088d4431082864f39534 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 397 1.6E-220 T 22-04-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 HRM2_RS17970 396d4d24a86a088d4431082864f39534 397 Gene3D G3DSA:3.40.50.300 4 214 3.0E-70 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17970 396d4d24a86a088d4431082864f39534 397 SUPERFAMILY SSF52540 9 229 8.6E-63 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17970 396d4d24a86a088d4431082864f39534 397 Pfam PF03144 Elongation factor Tu domain 2 228 296 1.2E-13 T 22-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 HRM2_RS17970 396d4d24a86a088d4431082864f39534 397 PANTHER PTHR23115:SF112 1 396 2.3E-242 T 22-04-2016 HRM2_RS17970 396d4d24a86a088d4431082864f39534 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 59.81 T 22-04-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 HRM2_RS17970 396d4d24a86a088d4431082864f39534 397 Gene3D G3DSA:2.40.30.10 215 301 3.0E-34 T 22-04-2016 HRM2_RS17970 396d4d24a86a088d4431082864f39534 397 PANTHER PTHR23115 1 396 2.3E-242 T 22-04-2016 HRM2_RS17970 396d4d24a86a088d4431082864f39534 397 SUPERFAMILY SSF50465 305 397 1.76E-34 T 22-04-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal HRM2_RS17970 396d4d24a86a088d4431082864f39534 397 Pfam PF03143 Elongation factor Tu C-terminal domain 301 395 1.1E-31 T 22-04-2016 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal HRM2_RS17970 396d4d24a86a088d4431082864f39534 397 Gene3D G3DSA:2.40.30.10 303 396 2.5E-44 T 22-04-2016 HRM2_RS17970 396d4d24a86a088d4431082864f39534 397 PRINTS PR00315 GTP-binding elongation factor signature 78 88 4.2E-25 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS17970 396d4d24a86a088d4431082864f39534 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 4.2E-25 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS17970 396d4d24a86a088d4431082864f39534 397 PRINTS PR00315 GTP-binding elongation factor signature 94 105 4.2E-25 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS17970 396d4d24a86a088d4431082864f39534 397 PRINTS PR00315 GTP-binding elongation factor signature 131 140 4.2E-25 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS17970 396d4d24a86a088d4431082864f39534 397 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.2E-25 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS17970 396d4d24a86a088d4431082864f39534 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 204 1.5E-59 T 22-04-2016 HRM2_RS17970 396d4d24a86a088d4431082864f39534 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 150 2.6E-16 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HRM2_RS17970 396d4d24a86a088d4431082864f39534 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 22-04-2016 IPR031157 Tr-type G domain, conserved site HRM2_RS17970 396d4d24a86a088d4431082864f39534 397 SUPERFAMILY SSF50447 208 304 6.86E-29 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain HRM2_RS06075 dd24081d52f6103cb90e7824faabd46c 230 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 222 9.7E-18 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS06075 dd24081d52f6103cb90e7824faabd46c 230 PANTHER PTHR30133 3 230 1.3E-88 T 22-04-2016 HRM2_RS06075 dd24081d52f6103cb90e7824faabd46c 230 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 9 117 1.3E-17 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HRM2_RS06075 dd24081d52f6103cb90e7824faabd46c 230 Gene3D G3DSA:1.10.3720.10 9 224 9.3E-40 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS06075 dd24081d52f6103cb90e7824faabd46c 230 SUPERFAMILY SSF161098 9 214 8.37E-38 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS16545 25e3d2fb7641694c741dc0405a5843d7 211 PANTHER PTHR32154:SF22 9 198 9.4E-36 T 22-04-2016 HRM2_RS16545 25e3d2fb7641694c741dc0405a5843d7 211 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 17 199 1.1E-31 T 22-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HRM2_RS16545 25e3d2fb7641694c741dc0405a5843d7 211 PANTHER PTHR32154 9 198 9.4E-36 T 22-04-2016 HRM2_RS16545 25e3d2fb7641694c741dc0405a5843d7 211 Gene3D G3DSA:3.40.920.10 9 206 8.8E-31 T 22-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HRM2_RS16545 25e3d2fb7641694c741dc0405a5843d7 211 SUPERFAMILY SSF53323 8 202 1.31E-31 T 22-04-2016 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 HRM2_RS06300 9ebb2333b17d47927f63376bd2f31a4c 374 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 329 353 - T 22-04-2016 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 HRM2_RS06300 9ebb2333b17d47927f63376bd2f31a4c 374 PANTHER PTHR30474 16 367 3.8E-138 T 22-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 HRM2_RS06300 9ebb2333b17d47927f63376bd2f31a4c 374 Pfam PF01098 Cell cycle protein 17 369 5.6E-109 T 22-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 HRM2_RS06300 9ebb2333b17d47927f63376bd2f31a4c 374 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 16 368 2.0E-123 T 22-04-2016 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 HRM2_RS06300 9ebb2333b17d47927f63376bd2f31a4c 374 PANTHER PTHR30474:SF2 16 367 3.8E-138 T 22-04-2016 HRM2_RS14115 a056c5fe9439c51545bcbd4e4d0514b7 166 SUPERFAMILY SSF50891 1 131 2.34E-55 T 22-04-2016 IPR029000 Cyclophilin-like domain HRM2_RS14115 a056c5fe9439c51545bcbd4e4d0514b7 166 Gene3D G3DSA:2.40.100.10 1 130 1.1E-56 T 22-04-2016 IPR029000 Cyclophilin-like domain HRM2_RS14115 a056c5fe9439c51545bcbd4e4d0514b7 166 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 93 105 9.2E-31 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 HRM2_RS14115 a056c5fe9439c51545bcbd4e4d0514b7 166 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 78 93 9.2E-31 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 HRM2_RS14115 a056c5fe9439c51545bcbd4e4d0514b7 166 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 38 50 9.2E-31 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 HRM2_RS14115 a056c5fe9439c51545bcbd4e4d0514b7 166 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 106 121 9.2E-31 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 HRM2_RS14115 a056c5fe9439c51545bcbd4e4d0514b7 166 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 12 27 9.2E-31 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 HRM2_RS14115 a056c5fe9439c51545bcbd4e4d0514b7 166 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 33 50 - T 22-04-2016 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 HRM2_RS14115 a056c5fe9439c51545bcbd4e4d0514b7 166 PIRSF PIRSF001467 1 154 4.1E-53 T 22-04-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 HRM2_RS14115 a056c5fe9439c51545bcbd4e4d0514b7 166 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 1 130 5.7E-45 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 HRM2_RS14115 a056c5fe9439c51545bcbd4e4d0514b7 166 PANTHER PTHR11071 1 126 4.8E-64 T 22-04-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 HRM2_RS11390 b7231a1bdecb8e06ff37b96d2ea39316 808 PIRSF PIRSF000854 2 803 0.0 T 22-04-2016 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|UniPathway: UPA00138 HRM2_RS11390 b7231a1bdecb8e06ff37b96d2ea39316 808 Gene3D G3DSA:3.20.20.60 487 799 3.9E-99 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HRM2_RS11390 b7231a1bdecb8e06ff37b96d2ea39316 808 SUPERFAMILY SSF56059 5 392 4.94E-103 T 22-04-2016 HRM2_RS11390 b7231a1bdecb8e06ff37b96d2ea39316 808 PANTHER PTHR22931:SF7 3 807 0.0 T 22-04-2016 HRM2_RS11390 b7231a1bdecb8e06ff37b96d2ea39316 808 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 8 799 0.0 T 22-04-2016 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|UniPathway: UPA00138 HRM2_RS11390 b7231a1bdecb8e06ff37b96d2ea39316 808 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 422 433 - T 22-04-2016 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 HRM2_RS11390 b7231a1bdecb8e06ff37b96d2ea39316 808 PANTHER PTHR22931 3 807 0.0 T 22-04-2016 HRM2_RS11390 b7231a1bdecb8e06ff37b96d2ea39316 808 SUPERFAMILY SSF52009 354 471 2.09E-31 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS11390 b7231a1bdecb8e06ff37b96d2ea39316 808 SUPERFAMILY SSF51621 469 800 1.75E-91 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HRM2_RS11390 b7231a1bdecb8e06ff37b96d2ea39316 808 Gene3D G3DSA:3.30.1490.20 6 196 5.8E-67 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HRM2_RS11390 b7231a1bdecb8e06ff37b96d2ea39316 808 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 703 721 - T 22-04-2016 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 HRM2_RS11390 b7231a1bdecb8e06ff37b96d2ea39316 808 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 486 798 2.8E-60 T 22-04-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 HRM2_RS11390 b7231a1bdecb8e06ff37b96d2ea39316 808 Gene3D G3DSA:3.50.30.10 380 475 1.6E-32 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS11390 b7231a1bdecb8e06ff37b96d2ea39316 808 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 20 353 7.0E-119 T 22-04-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 HRM2_RS11390 b7231a1bdecb8e06ff37b96d2ea39316 808 Pfam PF00391 PEP-utilising enzyme, mobile domain 392 463 3.4E-24 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS11390 b7231a1bdecb8e06ff37b96d2ea39316 808 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 756 768 7.5E-7 T 22-04-2016 HRM2_RS11390 b7231a1bdecb8e06ff37b96d2ea39316 808 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 703 718 7.5E-7 T 22-04-2016 HRM2_RS11390 b7231a1bdecb8e06ff37b96d2ea39316 808 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 720 735 7.5E-7 T 22-04-2016 HRM2_RS11390 b7231a1bdecb8e06ff37b96d2ea39316 808 Gene3D G3DSA:3.30.470.20 198 365 2.7E-53 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS16915 6b72355dc1847a50042a39ea0a3d00ca 301 PANTHER PTHR30349:SF5 1 290 6.0E-52 T 22-04-2016 HRM2_RS16915 6b72355dc1847a50042a39ea0a3d00ca 301 Gene3D G3DSA:1.10.443.10 112 293 6.5E-38 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS16915 6b72355dc1847a50042a39ea0a3d00ca 301 PANTHER PTHR30349 1 290 6.0E-52 T 22-04-2016 HRM2_RS16915 6b72355dc1847a50042a39ea0a3d00ca 301 Gene3D G3DSA:1.10.150.130 18 98 3.0E-14 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal HRM2_RS16915 6b72355dc1847a50042a39ea0a3d00ca 301 Pfam PF00589 Phage integrase family 111 287 1.5E-26 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS16915 6b72355dc1847a50042a39ea0a3d00ca 301 SUPERFAMILY SSF56349 17 289 1.15E-45 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HRM2_RS16915 6b72355dc1847a50042a39ea0a3d00ca 301 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 12 87 9.8E-11 T 22-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 HRM2_RS20255 4f2f11208122812f4a78eee1474fd1fe 394 Gene3D G3DSA:1.10.230.10 242 332 1.4E-28 T 22-04-2016 IPR016143 Citrate synthase-like, small alpha subdomain HRM2_RS20255 4f2f11208122812f4a78eee1474fd1fe 394 PANTHER PTHR11739 13 394 3.8E-128 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 HRM2_RS20255 4f2f11208122812f4a78eee1474fd1fe 394 PIRSF PIRSF001369 5 394 1.4E-119 T 22-04-2016 IPR024176 Citrate synthase, bacterial-type UniPathway: UPA00223 HRM2_RS20255 4f2f11208122812f4a78eee1474fd1fe 394 Gene3D G3DSA:1.10.580.10 20 241 4.8E-79 T 22-04-2016 IPR016142 Citrate synthase-like, large alpha subdomain UniPathway: UPA00223 HRM2_RS20255 4f2f11208122812f4a78eee1474fd1fe 394 PRINTS PR00143 Citrate synthase signature 338 352 3.9E-34 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 HRM2_RS20255 4f2f11208122812f4a78eee1474fd1fe 394 PRINTS PR00143 Citrate synthase signature 131 144 3.9E-34 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 HRM2_RS20255 4f2f11208122812f4a78eee1474fd1fe 394 PRINTS PR00143 Citrate synthase signature 180 195 3.9E-34 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 HRM2_RS20255 4f2f11208122812f4a78eee1474fd1fe 394 PRINTS PR00143 Citrate synthase signature 255 275 3.9E-34 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 HRM2_RS20255 4f2f11208122812f4a78eee1474fd1fe 394 PRINTS PR00143 Citrate synthase signature 318 334 3.9E-34 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 HRM2_RS20255 4f2f11208122812f4a78eee1474fd1fe 394 PRINTS PR00143 Citrate synthase signature 202 230 3.9E-34 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 HRM2_RS20255 4f2f11208122812f4a78eee1474fd1fe 394 Pfam PF00285 Citrate synthase, C-terminal domain 13 372 8.7E-116 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 HRM2_RS20255 4f2f11208122812f4a78eee1474fd1fe 394 SUPERFAMILY SSF48256 9 378 1.02E-111 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 HRM2_RS20255 4f2f11208122812f4a78eee1474fd1fe 394 PANTHER PTHR11739:SF4 13 394 3.8E-128 T 22-04-2016 HRM2_RS22065 3807f68b0f9e5693986682295d77243d 262 SMART SM00507 9 62 1.6E-4 T 22-04-2016 IPR003615 HNH nuclease HRM2_RS22065 3807f68b0f9e5693986682295d77243d 262 Pfam PF13395 HNH endonuclease 22 68 1.7E-10 T 22-04-2016 IPR003615 HNH nuclease HRM2_RS17880 81199d61e136cdbf00424fd6231b9c56 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.221 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17880 81199d61e136cdbf00424fd6231b9c56 92 PANTHER PTHR11880 1 90 4.7E-46 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17880 81199d61e136cdbf00424fd6231b9c56 92 SUPERFAMILY SSF54570 3 84 7.59E-35 T 22-04-2016 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 HRM2_RS17880 81199d61e136cdbf00424fd6231b9c56 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 4.4E-24 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17880 81199d61e136cdbf00424fd6231b9c56 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 4.4E-24 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17880 81199d61e136cdbf00424fd6231b9c56 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 4.4E-24 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17880 81199d61e136cdbf00424fd6231b9c56 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 90 4.2E-43 T 22-04-2016 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 HRM2_RS17880 81199d61e136cdbf00424fd6231b9c56 92 Gene3D G3DSA:3.30.860.10 1 91 1.2E-39 T 22-04-2016 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 HRM2_RS17880 81199d61e136cdbf00424fd6231b9c56 92 Pfam PF00203 Ribosomal protein S19 3 83 2.9E-37 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17880 81199d61e136cdbf00424fd6231b9c56 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 22-04-2016 IPR020934 Ribosomal protein S19 conserved site GO:0003723 HRM2_RS17880 81199d61e136cdbf00424fd6231b9c56 92 PIRSF PIRSF002144 1 92 4.5E-33 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17715 61694c4e4737e4e6604c193e1d7dbea8 154 PANTHER PTHR33540 1 129 6.1E-36 T 22-04-2016 HRM2_RS17715 61694c4e4737e4e6604c193e1d7dbea8 154 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 10 134 2.2E-33 T 22-04-2016 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 HRM2_RS17715 61694c4e4737e4e6604c193e1d7dbea8 154 SUPERFAMILY SSF52540 24 113 9.0E-19 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17715 61694c4e4737e4e6604c193e1d7dbea8 154 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 12 140 6.7E-30 T 22-04-2016 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 HRM2_RS17715 61694c4e4737e4e6604c193e1d7dbea8 154 Gene3D G3DSA:3.40.50.300 2 151 8.1E-39 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17715 61694c4e4737e4e6604c193e1d7dbea8 154 PANTHER PTHR33540:SF2 1 129 6.1E-36 T 22-04-2016 HRM2_RS00865 314854cd6f3a222fa591476a59688dc9 298 PANTHER PTHR24220 50 296 1.7E-127 T 22-04-2016 HRM2_RS00865 314854cd6f3a222fa591476a59688dc9 298 SMART SM00382 75 286 1.1E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS00865 314854cd6f3a222fa591476a59688dc9 298 Pfam PF00005 ABC transporter 67 222 3.8E-30 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS00865 314854cd6f3a222fa591476a59688dc9 298 Gene3D G3DSA:3.40.50.300 49 292 2.2E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00865 314854cd6f3a222fa591476a59688dc9 298 SUPERFAMILY SSF52540 48 293 1.45E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00865 314854cd6f3a222fa591476a59688dc9 298 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 50 298 4.0E-118 T 22-04-2016 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 HRM2_RS00865 314854cd6f3a222fa591476a59688dc9 298 PANTHER PTHR24220:SF585 50 296 1.7E-127 T 22-04-2016 HRM2_RS00865 314854cd6f3a222fa591476a59688dc9 298 ProSitePatterns PS00211 ABC transporters family signature. 195 209 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS00165 bfa398be4951e9eb5237501ef4f38476 318 SUPERFAMILY SSF56112 20 291 2.77E-23 T 22-04-2016 IPR011009 Protein kinase-like domain HRM2_RS00165 bfa398be4951e9eb5237501ef4f38476 318 Gene3D G3DSA:3.90.1200.10 93 293 5.5E-11 T 22-04-2016 HRM2_RS00165 bfa398be4951e9eb5237501ef4f38476 318 Pfam PF01636 Phosphotransferase enzyme family 26 252 5.0E-14 T 22-04-2016 IPR002575 Aminoglycoside phosphotransferase HRM2_RS02540 cc2be118b16774f05289e3ba8017d672 232 Pfam PF02470 MlaD protein 23 84 7.1E-6 T 22-04-2016 IPR003399 Mce/MlaD HRM2_RS13120 0ee9e062c8d3b38ec47f92e60ddcd455 1206 PIRSF PIRSF000980 15 1206 1.4E-303 T 22-04-2016 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 HRM2_RS13120 0ee9e062c8d3b38ec47f92e60ddcd455 1206 SUPERFAMILY SSF52540 16 369 1.17E-91 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13120 0ee9e062c8d3b38ec47f92e60ddcd455 1206 TIGRFAM TIGR01450 recC: exodeoxyribonuclease V, gamma subunit 17 1156 1.7E-293 T 22-04-2016 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 HRM2_RS13120 0ee9e062c8d3b38ec47f92e60ddcd455 1206 Gene3D G3DSA:1.10.10.160 104 203 6.3E-28 T 22-04-2016 IPR013986 DExx box DNA helicase domain HRM2_RS13120 0ee9e062c8d3b38ec47f92e60ddcd455 1206 Pfam PF04257 Exodeoxyribonuclease V, gamma subunit 16 849 3.7E-255 T 22-04-2016 HRM2_RS13120 0ee9e062c8d3b38ec47f92e60ddcd455 1206 PANTHER PTHR30591 9 783 3.2E-208 T 22-04-2016 HRM2_RS13120 0ee9e062c8d3b38ec47f92e60ddcd455 1206 PANTHER PTHR30591 806 1147 3.2E-208 T 22-04-2016 HRM2_RS13120 0ee9e062c8d3b38ec47f92e60ddcd455 1206 SUPERFAMILY SSF52540 379 852 8.07E-83 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13120 0ee9e062c8d3b38ec47f92e60ddcd455 1206 Hamap MF_01486 RecBCD enzyme subunit RecC [recC]. 15 1204 12.677 T 22-04-2016 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 HRM2_RS13120 0ee9e062c8d3b38ec47f92e60ddcd455 1206 PANTHER PTHR30591:SF1 9 783 3.2E-208 T 22-04-2016 HRM2_RS13120 0ee9e062c8d3b38ec47f92e60ddcd455 1206 PANTHER PTHR30591:SF1 806 1147 3.2E-208 T 22-04-2016 HRM2_RS13120 0ee9e062c8d3b38ec47f92e60ddcd455 1206 SUPERFAMILY SSF52980 1056 1202 1.45E-44 T 22-04-2016 IPR011335 Restriction endonuclease type II-like HRM2_RS13120 0ee9e062c8d3b38ec47f92e60ddcd455 1206 SUPERFAMILY SSF52980 869 1028 1.45E-44 T 22-04-2016 IPR011335 Restriction endonuclease type II-like HRM2_RS21460 0f62bf241b7d5ebb112c97ccc1124bfa 147 PANTHER PTHR35526:SF1 6 142 3.8E-17 T 22-04-2016 HRM2_RS21460 0f62bf241b7d5ebb112c97ccc1124bfa 147 Pfam PF13581 Histidine kinase-like ATPase domain 12 137 4.6E-20 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS21460 0f62bf241b7d5ebb112c97ccc1124bfa 147 PANTHER PTHR35526 6 142 3.8E-17 T 22-04-2016 HRM2_RS21460 0f62bf241b7d5ebb112c97ccc1124bfa 147 Gene3D G3DSA:3.30.565.10 20 131 9.0E-11 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS21460 0f62bf241b7d5ebb112c97ccc1124bfa 147 SUPERFAMILY SSF55874 34 132 2.88E-13 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS14940 d69a596427a31a112357f2aa75df48fa 510 Pfam PF00437 Type II/IV secretion system protein 136 398 7.7E-80 T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 HRM2_RS14940 d69a596427a31a112357f2aa75df48fa 510 SUPERFAMILY SSF160246 6 87 4.45E-16 T 22-04-2016 HRM2_RS14940 d69a596427a31a112357f2aa75df48fa 510 SUPERFAMILY SSF52540 117 507 3.82E-103 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14940 d69a596427a31a112357f2aa75df48fa 510 Gene3D G3DSA:3.30.450.90 105 232 7.6E-52 T 22-04-2016 HRM2_RS14940 d69a596427a31a112357f2aa75df48fa 510 Gene3D G3DSA:3.40.50.300 239 507 4.7E-99 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14940 d69a596427a31a112357f2aa75df48fa 510 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 327 341 - T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 HRM2_RS14940 d69a596427a31a112357f2aa75df48fa 510 PANTHER PTHR30258 21 509 1.8E-207 T 22-04-2016 HRM2_RS14940 d69a596427a31a112357f2aa75df48fa 510 PANTHER PTHR30258:SF2 21 509 1.8E-207 T 22-04-2016 HRM2_RS14940 d69a596427a31a112357f2aa75df48fa 510 TIGRFAM TIGR02533 type_II_gspE: type II secretion system protein E 22 507 9.1E-197 T 22-04-2016 IPR013369 Type II secretion system GspE GO:0005524|GO:0008565|GO:0015627|GO:0015628 HRM2_RS14940 d69a596427a31a112357f2aa75df48fa 510 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 7 90 4.3E-11 T 22-04-2016 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 HRM2_RS14940 d69a596427a31a112357f2aa75df48fa 510 SMART SM00382 260 386 0.002 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS17890 a04b7eb54a7b716c3fe93a38954f536a 95 Pfam PF00276 Ribosomal protein L23 5 91 1.9E-30 T 22-04-2016 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17890 a04b7eb54a7b716c3fe93a38954f536a 95 PANTHER PTHR11620 1 92 3.7E-23 T 22-04-2016 HRM2_RS17890 a04b7eb54a7b716c3fe93a38954f536a 95 SUPERFAMILY SSF54189 4 94 1.01E-29 T 22-04-2016 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17890 a04b7eb54a7b716c3fe93a38954f536a 95 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 4 94 22.087 T 22-04-2016 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17890 a04b7eb54a7b716c3fe93a38954f536a 95 Gene3D G3DSA:3.30.70.330 1 95 9.2E-33 T 22-04-2016 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 HRM2_RS03070 86ea8e5716be7cb37b9b1adfcd2802f3 384 Pfam PF02608 Basic membrane protein 28 287 6.2E-44 T 22-04-2016 IPR003760 Basic membrane lipoprotein GO:0005886 HRM2_RS03070 86ea8e5716be7cb37b9b1adfcd2802f3 384 Gene3D G3DSA:3.40.50.2300 149 288 7.2E-35 T 22-04-2016 HRM2_RS03070 86ea8e5716be7cb37b9b1adfcd2802f3 384 PANTHER PTHR34296:SF1 21 375 8.4E-109 T 22-04-2016 HRM2_RS03070 86ea8e5716be7cb37b9b1adfcd2802f3 384 Gene3D G3DSA:3.40.50.2300 24 148 7.1E-40 T 22-04-2016 HRM2_RS03070 86ea8e5716be7cb37b9b1adfcd2802f3 384 PANTHER PTHR34296 21 375 8.4E-109 T 22-04-2016 HRM2_RS25650 c8618829c1dd63b51cac904bfc9f22e1 268 Gene3D G3DSA:3.40.50.150 138 224 3.6E-9 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS25650 c8618829c1dd63b51cac904bfc9f22e1 268 SUPERFAMILY SSF53335 133 217 1.3E-10 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS20325 f6e56108d9328d80a45c18bce90391ea 836 Gene3D G3DSA:1.20.1560.10 25 317 2.7E-46 T 22-04-2016 HRM2_RS20325 f6e56108d9328d80a45c18bce90391ea 836 SUPERFAMILY SSF90123 21 330 4.84E-48 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HRM2_RS20325 f6e56108d9328d80a45c18bce90391ea 836 SMART SM00382 367 820 3.1E-15 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS20325 f6e56108d9328d80a45c18bce90391ea 836 Pfam PF00005 ABC transporter 661 765 3.7E-10 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS20325 f6e56108d9328d80a45c18bce90391ea 836 Pfam PF00005 ABC transporter 359 460 4.2E-13 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS20325 f6e56108d9328d80a45c18bce90391ea 836 SUPERFAMILY SSF52540 718 830 2.67E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20325 f6e56108d9328d80a45c18bce90391ea 836 SUPERFAMILY SSF52540 345 452 2.67E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20325 f6e56108d9328d80a45c18bce90391ea 836 Gene3D G3DSA:3.40.50.300 660 834 7.1E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20325 f6e56108d9328d80a45c18bce90391ea 836 Pfam PF00664 ABC transporter transmembrane region 48 288 2.5E-23 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HRM2_RS20325 f6e56108d9328d80a45c18bce90391ea 836 Gene3D G3DSA:3.40.50.300 341 442 2.5E-24 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20325 f6e56108d9328d80a45c18bce90391ea 836 PANTHER PTHR24221 716 836 4.1E-97 T 22-04-2016 HRM2_RS20325 f6e56108d9328d80a45c18bce90391ea 836 PANTHER PTHR24221 27 468 4.1E-97 T 22-04-2016 HRM2_RS20325 f6e56108d9328d80a45c18bce90391ea 836 PANTHER PTHR24221:SF138 716 836 4.1E-97 T 22-04-2016 HRM2_RS20325 f6e56108d9328d80a45c18bce90391ea 836 PANTHER PTHR24221:SF138 27 468 4.1E-97 T 22-04-2016 HRM2_RS20325 f6e56108d9328d80a45c18bce90391ea 836 ProSitePatterns PS00211 ABC transporters family signature. 737 751 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS15105 f89d02913be2795c51a0f4f6923d07d3 549 SUPERFAMILY SSF48592 6 133 1.45E-75 T 22-04-2016 HRM2_RS15105 f89d02913be2795c51a0f4f6923d07d3 549 SUPERFAMILY SSF48592 405 519 1.45E-75 T 22-04-2016 HRM2_RS15105 f89d02913be2795c51a0f4f6923d07d3 549 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 525 2.9E-255 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 HRM2_RS15105 f89d02913be2795c51a0f4f6923d07d3 549 Gene3D G3DSA:1.10.560.10 3 195 2.2E-46 T 22-04-2016 IPR027413 GroEL-like equatorial domain HRM2_RS15105 f89d02913be2795c51a0f4f6923d07d3 549 Gene3D G3DSA:1.10.560.10 369 516 5.7E-42 T 22-04-2016 IPR027413 GroEL-like equatorial domain HRM2_RS15105 f89d02913be2795c51a0f4f6923d07d3 549 PANTHER PTHR11353 1 549 4.4E-248 T 22-04-2016 HRM2_RS15105 f89d02913be2795c51a0f4f6923d07d3 549 ProSitePatterns PS00296 Chaperonins cpn60 signature. 404 415 - T 22-04-2016 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 HRM2_RS15105 f89d02913be2795c51a0f4f6923d07d3 549 Gene3D G3DSA:3.50.7.10 196 368 4.4E-95 T 22-04-2016 IPR027409 GroEL-like apical domain HRM2_RS15105 f89d02913be2795c51a0f4f6923d07d3 549 SUPERFAMILY SSF54849 136 203 4.58E-24 T 22-04-2016 HRM2_RS15105 f89d02913be2795c51a0f4f6923d07d3 549 Hamap MF_00600 60 kDa chaperonin [groL]. 1 548 41.466 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 HRM2_RS15105 f89d02913be2795c51a0f4f6923d07d3 549 PRINTS PR00298 60kDa chaperonin signature 267 290 4.1E-74 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 HRM2_RS15105 f89d02913be2795c51a0f4f6923d07d3 549 PRINTS PR00298 60kDa chaperonin signature 349 374 4.1E-74 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 HRM2_RS15105 f89d02913be2795c51a0f4f6923d07d3 549 PRINTS PR00298 60kDa chaperonin signature 26 52 4.1E-74 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 HRM2_RS15105 f89d02913be2795c51a0f4f6923d07d3 549 PRINTS PR00298 60kDa chaperonin signature 397 418 4.1E-74 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 HRM2_RS15105 f89d02913be2795c51a0f4f6923d07d3 549 PRINTS PR00298 60kDa chaperonin signature 82 109 4.1E-74 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 HRM2_RS15105 f89d02913be2795c51a0f4f6923d07d3 549 SUPERFAMILY SSF52029 183 375 1.02E-84 T 22-04-2016 IPR027409 GroEL-like apical domain HRM2_RS15105 f89d02913be2795c51a0f4f6923d07d3 549 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 523 5.9E-101 T 22-04-2016 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 HRM2_RS19720 d164c790f64590b04939ffeb719786b5 130 Pfam PF02036 SCP-2 sterol transfer family 26 108 6.3E-5 T 22-04-2016 IPR003033 SCP2 sterol-binding domain HRM2_RS19720 d164c790f64590b04939ffeb719786b5 130 Gene3D G3DSA:3.30.1050.10 30 113 5.7E-7 T 22-04-2016 IPR003033 SCP2 sterol-binding domain HRM2_RS19720 d164c790f64590b04939ffeb719786b5 130 SUPERFAMILY SSF55718 7 119 8.48E-11 T 22-04-2016 IPR003033 SCP2 sterol-binding domain HRM2_RS24440 1bf1591b8125012110c106bc2db4fdb4 393 PANTHER PTHR23501 28 385 2.5E-31 T 22-04-2016 HRM2_RS24440 1bf1591b8125012110c106bc2db4fdb4 393 Pfam PF07690 Major Facilitator Superfamily 17 195 8.0E-25 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS24440 1bf1591b8125012110c106bc2db4fdb4 393 Gene3D G3DSA:1.20.1250.20 13 183 8.7E-28 T 22-04-2016 HRM2_RS24440 1bf1591b8125012110c106bc2db4fdb4 393 Gene3D G3DSA:1.20.1250.20 215 385 1.4E-16 T 22-04-2016 HRM2_RS24440 1bf1591b8125012110c106bc2db4fdb4 393 SUPERFAMILY SSF103473 12 388 2.49E-52 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS00415 21c4095363a928947e821431ac30d036 465 Gene3D G3DSA:1.10.780.10 35 216 4.7E-24 T 22-04-2016 HRM2_RS00415 21c4095363a928947e821431ac30d036 465 Gene3D G3DSA:1.20.850.10 237 444 1.2E-63 T 22-04-2016 HRM2_RS00415 21c4095363a928947e821431ac30d036 465 SUPERFAMILY SSF48695 48 427 1.59E-80 T 22-04-2016 IPR011031 Multihaem cytochrome HRM2_RS00415 21c4095363a928947e821431ac30d036 465 Pfam PF13447 Seven times multi-haem cytochrome CxxCH 203 379 1.3E-30 T 22-04-2016 HRM2_RS00415 21c4095363a928947e821431ac30d036 465 Pfam PF13435 Cytochrome c554 and c-prime 125 195 2.1E-6 T 22-04-2016 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674|UniPathway: UPA00653 HRM2_RS13375 7acaa6b111321706f3ec38cafa6f1410 455 Gene3D G3DSA:3.30.70.1170 193 251 1.7E-6 T 22-04-2016 HRM2_RS13375 7acaa6b111321706f3ec38cafa6f1410 455 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 17 454 2.0E-104 T 22-04-2016 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HRM2_RS13375 7acaa6b111321706f3ec38cafa6f1410 455 Gene3D G3DSA:1.10.940.10 14 168 2.0E-37 T 22-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 HRM2_RS13375 7acaa6b111321706f3ec38cafa6f1410 455 PANTHER PTHR22807 35 454 7.5E-121 T 22-04-2016 HRM2_RS13375 7acaa6b111321706f3ec38cafa6f1410 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 340 352 1.3E-27 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HRM2_RS13375 7acaa6b111321706f3ec38cafa6f1410 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 272 282 1.3E-27 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HRM2_RS13375 7acaa6b111321706f3ec38cafa6f1410 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 390 406 1.3E-27 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HRM2_RS13375 7acaa6b111321706f3ec38cafa6f1410 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 243 257 1.3E-27 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HRM2_RS13375 7acaa6b111321706f3ec38cafa6f1410 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 437 454 1.3E-27 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HRM2_RS13375 7acaa6b111321706f3ec38cafa6f1410 455 SUPERFAMILY SSF53335 161 454 6.23E-73 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS13375 7acaa6b111321706f3ec38cafa6f1410 455 Gene3D G3DSA:3.40.50.150 254 454 5.9E-58 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS13375 7acaa6b111321706f3ec38cafa6f1410 455 Pfam PF01189 16S rRNA methyltransferase RsmB/F 261 452 2.2E-58 T 22-04-2016 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HRM2_RS13375 7acaa6b111321706f3ec38cafa6f1410 455 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 339 350 - T 22-04-2016 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HRM2_RS13375 7acaa6b111321706f3ec38cafa6f1410 455 SUPERFAMILY SSF48013 15 168 4.71E-31 T 22-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 HRM2_RS13375 7acaa6b111321706f3ec38cafa6f1410 455 PANTHER PTHR22807:SF30 35 454 7.5E-121 T 22-04-2016 HRM2_RS13375 7acaa6b111321706f3ec38cafa6f1410 455 Pfam PF01029 NusB family 17 138 2.3E-27 T 22-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 HRM2_RS22765 887490f3d914b01ab80db23437837157 370 SUPERFAMILY SSF51735 137 303 4.44E-50 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS22765 887490f3d914b01ab80db23437837157 370 Gene3D G3DSA:3.40.50.1770 1 173 4.8E-57 T 22-04-2016 HRM2_RS22765 887490f3d914b01ab80db23437837157 370 PIRSF PIRSF000183 1 370 8.0E-157 T 22-04-2016 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|UniPathway: UPA00527 HRM2_RS22765 887490f3d914b01ab80db23437837157 370 SUPERFAMILY SSF52283 305 360 1.87E-61 T 22-04-2016 HRM2_RS22765 887490f3d914b01ab80db23437837157 370 SUPERFAMILY SSF52283 1 137 1.87E-61 T 22-04-2016 HRM2_RS22765 887490f3d914b01ab80db23437837157 370 Gene3D G3DSA:3.50.50.60 174 199 5.3E-7 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS22765 887490f3d914b01ab80db23437837157 370 Gene3D G3DSA:3.40.50.1770 200 359 3.0E-29 T 22-04-2016 HRM2_RS22765 887490f3d914b01ab80db23437837157 370 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 173 198 - T 22-04-2016 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|UniPathway: UPA00527 HRM2_RS22765 887490f3d914b01ab80db23437837157 370 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 3.9E-83 T 22-04-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain HRM2_RS22765 887490f3d914b01ab80db23437837157 370 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 368 2.8E-145 T 22-04-2016 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|UniPathway: UPA00527 HRM2_RS22765 887490f3d914b01ab80db23437837157 370 SMART SM01003 4 137 9.2E-70 T 22-04-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal HRM2_RS22765 887490f3d914b01ab80db23437837157 370 PANTHER PTHR10160 1 367 2.1E-189 T 22-04-2016 HRM2_RS22765 887490f3d914b01ab80db23437837157 370 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 2.6E-43 T 22-04-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal HRM2_RS22765 887490f3d914b01ab80db23437837157 370 SMART SM01002 149 297 5.8E-85 T 22-04-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain HRM2_RS10005 d4bb7d7940999ba584fbe0e5e7f998bb 254 SMART SM00382 33 228 8.1E-18 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS10005 d4bb7d7940999ba584fbe0e5e7f998bb 254 Gene3D G3DSA:3.40.50.300 2 224 8.1E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10005 d4bb7d7940999ba584fbe0e5e7f998bb 254 Pfam PF00005 ABC transporter 24 173 1.0E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS10005 d4bb7d7940999ba584fbe0e5e7f998bb 254 SUPERFAMILY SSF52540 5 235 1.2E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10005 d4bb7d7940999ba584fbe0e5e7f998bb 254 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS10005 d4bb7d7940999ba584fbe0e5e7f998bb 254 PANTHER PTHR24220:SF86 6 223 1.8E-91 T 22-04-2016 HRM2_RS10005 d4bb7d7940999ba584fbe0e5e7f998bb 254 PANTHER PTHR24220 6 223 1.8E-91 T 22-04-2016 HRM2_RS06450 e65a26043725423ca0668c74c2137424 874 Gene3D G3DSA:3.40.50.2300 756 873 3.5E-29 T 22-04-2016 HRM2_RS06450 e65a26043725423ca0668c74c2137424 874 Gene3D G3DSA:3.30.565.10 558 737 3.9E-37 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS06450 e65a26043725423ca0668c74c2137424 874 SMART SM00448 755 868 1.4E-22 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS06450 e65a26043725423ca0668c74c2137424 874 Gene3D G3DSA:1.10.287.130 502 557 5.2E-5 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS06450 e65a26043725423ca0668c74c2137424 874 PRINTS PR00344 Bacterial sensor protein C-terminal signature 696 714 3.3E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS06450 e65a26043725423ca0668c74c2137424 874 PRINTS PR00344 Bacterial sensor protein C-terminal signature 683 693 3.3E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS06450 e65a26043725423ca0668c74c2137424 874 PRINTS PR00344 Bacterial sensor protein C-terminal signature 720 733 3.3E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS06450 e65a26043725423ca0668c74c2137424 874 PRINTS PR00344 Bacterial sensor protein C-terminal signature 665 679 3.3E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS06450 e65a26043725423ca0668c74c2137424 874 SUPERFAMILY SSF47384 500 570 2.94E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS06450 e65a26043725423ca0668c74c2137424 874 SUPERFAMILY SSF55874 562 735 4.58E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS06450 e65a26043725423ca0668c74c2137424 874 Pfam PF05226 CHASE2 domain 27 312 1.3E-45 T 22-04-2016 IPR007890 CHASE2 HRM2_RS06450 e65a26043725423ca0668c74c2137424 874 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 613 734 5.5E-20 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS06450 e65a26043725423ca0668c74c2137424 874 SUPERFAMILY SSF52172 756 873 2.7E-28 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS06450 e65a26043725423ca0668c74c2137424 874 SMART SM00388 506 572 4.8E-5 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS06450 e65a26043725423ca0668c74c2137424 874 SMART SM01080 36 313 1.3E-55 T 22-04-2016 IPR007890 CHASE2 HRM2_RS06450 e65a26043725423ca0668c74c2137424 874 PANTHER PTHR24423 442 874 2.5E-118 T 22-04-2016 HRM2_RS06450 e65a26043725423ca0668c74c2137424 874 PANTHER PTHR24423 213 224 2.5E-118 T 22-04-2016 HRM2_RS06450 e65a26043725423ca0668c74c2137424 874 PANTHER PTHR24423:SF544 442 874 2.5E-118 T 22-04-2016 HRM2_RS06450 e65a26043725423ca0668c74c2137424 874 PANTHER PTHR24423:SF544 213 224 2.5E-118 T 22-04-2016 HRM2_RS06450 e65a26043725423ca0668c74c2137424 874 SMART SM00387 612 736 3.4E-30 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS06450 e65a26043725423ca0668c74c2137424 874 Pfam PF00072 Response regulator receiver domain 758 868 2.3E-20 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS10555 b295d45e7d14bd9ac757cd079f7565af 204 PANTHER PTHR10516:SF320 85 204 3.1E-51 T 22-04-2016 HRM2_RS10555 b295d45e7d14bd9ac757cd079f7565af 204 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 2 106 2.0E-29 T 22-04-2016 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 HRM2_RS10555 b295d45e7d14bd9ac757cd079f7565af 204 SUPERFAMILY SSF54534 2 204 7.75E-57 T 22-04-2016 HRM2_RS10555 b295d45e7d14bd9ac757cd079f7565af 204 Gene3D G3DSA:1.10.287.460 4 89 1.3E-27 T 22-04-2016 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 HRM2_RS10555 b295d45e7d14bd9ac757cd079f7565af 204 PANTHER PTHR10516 85 204 3.1E-51 T 22-04-2016 IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type HRM2_RS10555 b295d45e7d14bd9ac757cd079f7565af 204 Gene3D G3DSA:3.10.50.40 90 203 6.3E-42 T 22-04-2016 HRM2_RS10555 b295d45e7d14bd9ac757cd079f7565af 204 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 114 201 1.0E-23 T 22-04-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 HRM2_RS18040 59e2894bb538abe64dc663275d7c2c82 391 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 3 391 38.869 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HRM2_RS18040 59e2894bb538abe64dc663275d7c2c82 391 Pfam PF00162 Phosphoglycerate kinase 4 382 2.9E-152 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HRM2_RS18040 59e2894bb538abe64dc663275d7c2c82 391 PRINTS PR00477 Phosphoglycerate kinase family signature 30 52 2.0E-80 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HRM2_RS18040 59e2894bb538abe64dc663275d7c2c82 391 PRINTS PR00477 Phosphoglycerate kinase family signature 108 123 2.0E-80 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HRM2_RS18040 59e2894bb538abe64dc663275d7c2c82 391 PRINTS PR00477 Phosphoglycerate kinase family signature 190 209 2.0E-80 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HRM2_RS18040 59e2894bb538abe64dc663275d7c2c82 391 PRINTS PR00477 Phosphoglycerate kinase family signature 345 356 2.0E-80 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HRM2_RS18040 59e2894bb538abe64dc663275d7c2c82 391 PRINTS PR00477 Phosphoglycerate kinase family signature 8 24 2.0E-80 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HRM2_RS18040 59e2894bb538abe64dc663275d7c2c82 391 PRINTS PR00477 Phosphoglycerate kinase family signature 312 337 2.0E-80 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HRM2_RS18040 59e2894bb538abe64dc663275d7c2c82 391 PRINTS PR00477 Phosphoglycerate kinase family signature 167 189 2.0E-80 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HRM2_RS18040 59e2894bb538abe64dc663275d7c2c82 391 PRINTS PR00477 Phosphoglycerate kinase family signature 368 385 2.0E-80 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HRM2_RS18040 59e2894bb538abe64dc663275d7c2c82 391 PRINTS PR00477 Phosphoglycerate kinase family signature 136 158 2.0E-80 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HRM2_RS18040 59e2894bb538abe64dc663275d7c2c82 391 Gene3D G3DSA:3.40.50.1270 180 380 3.7E-81 T 22-04-2016 IPR015901 Phosphoglycerate kinase, C-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HRM2_RS18040 59e2894bb538abe64dc663275d7c2c82 391 PIRSF PIRSF000724 1 391 1.5E-145 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HRM2_RS18040 59e2894bb538abe64dc663275d7c2c82 391 PANTHER PTHR11406 2 391 1.2E-199 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HRM2_RS18040 59e2894bb538abe64dc663275d7c2c82 391 Gene3D G3DSA:3.40.50.1260 1 179 1.1E-69 T 22-04-2016 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HRM2_RS18040 59e2894bb538abe64dc663275d7c2c82 391 SUPERFAMILY SSF53748 2 391 4.0E-147 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HRM2_RS14020 8f0610e83258154b52991b417ad90b66 217 SUPERFAMILY SSF55821 9 210 1.49E-80 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain HRM2_RS14020 8f0610e83258154b52991b417ad90b66 217 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 13 209 5.3E-73 T 22-04-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 HRM2_RS14020 8f0610e83258154b52991b417ad90b66 217 PANTHER PTHR21327:SF15 1 215 8.8E-129 T 22-04-2016 HRM2_RS14020 8f0610e83258154b52991b417ad90b66 217 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 11 213 40.941 T 22-04-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 HRM2_RS14020 8f0610e83258154b52991b417ad90b66 217 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 18 208 1.0E-78 T 22-04-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 HRM2_RS14020 8f0610e83258154b52991b417ad90b66 217 PANTHER PTHR21327 1 215 8.8E-129 T 22-04-2016 HRM2_RS14020 8f0610e83258154b52991b417ad90b66 217 Gene3D G3DSA:3.90.870.10 9 211 1.8E-89 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain HRM2_RS03850 2a3954fe85c9fa0fd04ff9ef5dac13a7 467 PANTHER PTHR32071:SF5 1 461 2.0E-155 T 22-04-2016 HRM2_RS03850 2a3954fe85c9fa0fd04ff9ef5dac13a7 467 SMART SM00448 2 113 2.3E-22 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS03850 2a3954fe85c9fa0fd04ff9ef5dac13a7 467 SUPERFAMILY SSF52540 136 375 1.36E-63 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03850 2a3954fe85c9fa0fd04ff9ef5dac13a7 467 Gene3D G3DSA:3.40.50.2300 2 123 6.6E-26 T 22-04-2016 HRM2_RS03850 2a3954fe85c9fa0fd04ff9ef5dac13a7 467 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 350 359 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS03850 2a3954fe85c9fa0fd04ff9ef5dac13a7 467 Gene3D G3DSA:1.10.10.60 414 461 1.1E-16 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS03850 2a3954fe85c9fa0fd04ff9ef5dac13a7 467 Gene3D G3DSA:1.10.10.60 334 380 1.1E-16 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS03850 2a3954fe85c9fa0fd04ff9ef5dac13a7 467 Pfam PF00072 Response regulator receiver domain 4 108 1.6E-18 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS03850 2a3954fe85c9fa0fd04ff9ef5dac13a7 467 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 161 174 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS03850 2a3954fe85c9fa0fd04ff9ef5dac13a7 467 Pfam PF00158 Sigma-54 interaction domain 137 303 3.6E-63 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS03850 2a3954fe85c9fa0fd04ff9ef5dac13a7 467 SUPERFAMILY SSF52172 1 182 1.99E-33 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS03850 2a3954fe85c9fa0fd04ff9ef5dac13a7 467 PANTHER PTHR32071 1 461 2.0E-155 T 22-04-2016 HRM2_RS03850 2a3954fe85c9fa0fd04ff9ef5dac13a7 467 SMART SM00382 157 319 1.7E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS03850 2a3954fe85c9fa0fd04ff9ef5dac13a7 467 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 223 238 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS03850 2a3954fe85c9fa0fd04ff9ef5dac13a7 467 Gene3D G3DSA:3.40.50.300 136 309 5.3E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21645 82270b5a5427b0ea9b0f15e24e470cea 291 Pfam PF02574 Homocysteine S-methyltransferase 1 289 6.6E-50 T 22-04-2016 IPR003726 Homocysteine-binding domain HRM2_RS21645 82270b5a5427b0ea9b0f15e24e470cea 291 PANTHER PTHR11103:SF7 1 290 1.5E-38 T 22-04-2016 HRM2_RS21645 82270b5a5427b0ea9b0f15e24e470cea 291 PANTHER PTHR11103 1 290 1.5E-38 T 22-04-2016 HRM2_RS21645 82270b5a5427b0ea9b0f15e24e470cea 291 PIRSF PIRSF037505 4 291 1.0E-7 T 22-04-2016 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 UniPathway: UPA00051 HRM2_RS21645 82270b5a5427b0ea9b0f15e24e470cea 291 Gene3D G3DSA:3.20.20.330 1 290 1.9E-65 T 22-04-2016 IPR003726 Homocysteine-binding domain HRM2_RS21645 82270b5a5427b0ea9b0f15e24e470cea 291 SUPERFAMILY SSF82282 1 290 9.55E-70 T 22-04-2016 IPR003726 Homocysteine-binding domain HRM2_RS16500 f38817ce60e2f7cef9750fb3b0d97305 253 SUPERFAMILY SSF51366 3 249 8.67E-75 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 HRM2_RS16500 f38817ce60e2f7cef9750fb3b0d97305 253 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 9 240 1.0E-64 T 22-04-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 HRM2_RS16500 f38817ce60e2f7cef9750fb3b0d97305 253 Pfam PF00290 Tryptophan synthase alpha chain 10 240 4.6E-72 T 22-04-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 HRM2_RS16500 f38817ce60e2f7cef9750fb3b0d97305 253 PANTHER PTHR10314 72 127 3.6E-14 T 22-04-2016 HRM2_RS16500 f38817ce60e2f7cef9750fb3b0d97305 253 PANTHER PTHR10314 21 49 3.6E-14 T 22-04-2016 HRM2_RS16500 f38817ce60e2f7cef9750fb3b0d97305 253 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 46 59 - T 22-04-2016 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 HRM2_RS16500 f38817ce60e2f7cef9750fb3b0d97305 253 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 12 252 28.328 T 22-04-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 HRM2_RS16500 f38817ce60e2f7cef9750fb3b0d97305 253 PANTHER PTHR10314:SF4 72 127 3.6E-14 T 22-04-2016 HRM2_RS16500 f38817ce60e2f7cef9750fb3b0d97305 253 PANTHER PTHR10314:SF4 21 49 3.6E-14 T 22-04-2016 HRM2_RS16500 f38817ce60e2f7cef9750fb3b0d97305 253 Gene3D G3DSA:3.20.20.70 3 252 4.8E-83 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS00950 23a410c04ce67266bdc8c62b13fedbaf 667 Gene3D G3DSA:3.50.50.60 515 634 7.0E-12 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS00950 23a410c04ce67266bdc8c62b13fedbaf 667 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 503 521 1.0E-19 T 22-04-2016 HRM2_RS00950 23a410c04ce67266bdc8c62b13fedbaf 667 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 615 631 1.0E-19 T 22-04-2016 HRM2_RS00950 23a410c04ce67266bdc8c62b13fedbaf 667 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 463 481 1.0E-19 T 22-04-2016 HRM2_RS00950 23a410c04ce67266bdc8c62b13fedbaf 667 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 381 400 1.0E-19 T 22-04-2016 HRM2_RS00950 23a410c04ce67266bdc8c62b13fedbaf 667 Gene3D G3DSA:3.20.20.70 3 371 7.0E-116 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS00950 23a410c04ce67266bdc8c62b13fedbaf 667 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 380 402 1.2E-8 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HRM2_RS00950 23a410c04ce67266bdc8c62b13fedbaf 667 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 499 523 1.2E-8 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HRM2_RS00950 23a410c04ce67266bdc8c62b13fedbaf 667 SUPERFAMILY SSF51395 3 366 1.6E-104 T 22-04-2016 HRM2_RS00950 23a410c04ce67266bdc8c62b13fedbaf 667 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 334 1.8E-64 T 22-04-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 HRM2_RS00950 23a410c04ce67266bdc8c62b13fedbaf 667 PANTHER PTHR22893 5 421 3.3E-139 T 22-04-2016 HRM2_RS00950 23a410c04ce67266bdc8c62b13fedbaf 667 PANTHER PTHR22893:SF25 5 421 3.3E-139 T 22-04-2016 HRM2_RS00950 23a410c04ce67266bdc8c62b13fedbaf 667 SUPERFAMILY SSF51905 355 524 3.43E-38 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS00950 23a410c04ce67266bdc8c62b13fedbaf 667 SUPERFAMILY SSF51905 554 666 3.43E-38 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS00950 23a410c04ce67266bdc8c62b13fedbaf 667 Gene3D G3DSA:3.40.50.720 377 514 5.2E-41 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS00950 23a410c04ce67266bdc8c62b13fedbaf 667 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 379 640 4.1E-31 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 SMART SM00028 197 230 8.4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 SMART SM00028 436 469 0.012 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 SMART SM00028 606 640 64.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 SMART SM00028 675 708 240.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 SMART SM00028 402 435 13.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 SMART SM00028 641 674 140.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 SMART SM00028 368 401 0.71 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 SMART SM00028 538 571 480.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 SMART SM00028 334 367 180.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 SMART SM00028 61 94 0.75 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 SMART SM00028 572 605 47.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 SMART SM00028 300 333 75.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 SMART SM00028 129 162 120.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 SMART SM00028 27 60 24.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 Gene3D G3DSA:1.25.40.10 196 441 1.8E-33 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 Gene3D G3DSA:1.25.40.10 442 701 8.1E-43 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 Gene3D G3DSA:1.25.40.10 32 187 1.1E-22 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 SUPERFAMILY SSF48452 309 619 9.1E-30 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 SUPERFAMILY SSF48452 152 288 4.74E-14 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 SUPERFAMILY SSF48452 591 701 1.19E-14 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 Pfam PF14559 Tetratricopeptide repeat 621 674 6.1E-6 T 22-04-2016 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 Pfam PF14559 Tetratricopeptide repeat 211 268 6.2E-6 T 22-04-2016 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 Pfam PF14559 Tetratricopeptide repeat 455 511 6.4E-6 T 22-04-2016 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 SUPERFAMILY SSF48452 32 189 1.25E-20 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 Pfam PF13432 Tetratricopeptide repeat 67 117 3.1E-5 T 22-04-2016 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 Pfam PF13432 Tetratricopeptide repeat 373 436 0.003 T 22-04-2016 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 PANTHER PTHR23083 29 91 9.4E-69 T 22-04-2016 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 PANTHER PTHR23083 313 383 9.4E-69 T 22-04-2016 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 PANTHER PTHR23083 538 701 9.4E-69 T 22-04-2016 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 PANTHER PTHR23083 418 469 9.4E-69 T 22-04-2016 HRM2_RS10060 ce2578fab0ce4ed6ddb6f1f4a4475550 771 PANTHER PTHR23083 126 243 9.4E-69 T 22-04-2016 HRM2_RS25540 298caa24af7c8cc2ac8f1552214051a9 252 SUPERFAMILY SSF53146 1 108 5.76E-15 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS25540 298caa24af7c8cc2ac8f1552214051a9 252 Gene3D G3DSA:3.30.420.130 1 108 9.1E-17 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS25540 298caa24af7c8cc2ac8f1552214051a9 252 Pfam PF03773 Predicted permease 110 245 1.7E-10 T 22-04-2016 IPR005524 Predicted permease DUF318 HRM2_RS25540 298caa24af7c8cc2ac8f1552214051a9 252 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 14 102 7.3E-9 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS19735 5d27565db94e5b37dcf1fe123f67c0bb 395 SUPERFAMILY SSF103473 16 391 1.29E-40 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS19735 5d27565db94e5b37dcf1fe123f67c0bb 395 PANTHER PTHR23530:SF1 2 392 3.7E-70 T 22-04-2016 HRM2_RS19735 5d27565db94e5b37dcf1fe123f67c0bb 395 PANTHER PTHR23530 2 392 3.7E-70 T 22-04-2016 HRM2_RS19735 5d27565db94e5b37dcf1fe123f67c0bb 395 Pfam PF07690 Major Facilitator Superfamily 12 346 1.9E-20 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS19735 5d27565db94e5b37dcf1fe123f67c0bb 395 Gene3D G3DSA:1.20.1250.20 213 384 4.1E-11 T 22-04-2016 HRM2_RS19735 5d27565db94e5b37dcf1fe123f67c0bb 395 Gene3D G3DSA:1.20.1250.20 17 189 3.3E-25 T 22-04-2016 HRM2_RS03440 703e46b859678b35daf4568d61bb96a7 340 SUPERFAMILY SSF53218 172 338 3.93E-31 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS03440 703e46b859678b35daf4568d61bb96a7 340 PANTHER PTHR10192:SF13 81 316 8.9E-50 T 22-04-2016 HRM2_RS03440 703e46b859678b35daf4568d61bb96a7 340 PANTHER PTHR10192 81 316 8.9E-50 T 22-04-2016 HRM2_RS03440 703e46b859678b35daf4568d61bb96a7 340 Pfam PF00994 Probable molybdopterin binding domain 174 305 3.6E-19 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS03440 703e46b859678b35daf4568d61bb96a7 340 Gene3D G3DSA:3.40.980.10 161 306 1.1E-25 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS03440 703e46b859678b35daf4568d61bb96a7 340 SMART SM00852 174 306 6.6E-19 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS19210 0241b8d16edbc70abebe725c3579fd86 611 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 11 83 1.9E-13 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 HRM2_RS19210 0241b8d16edbc70abebe725c3579fd86 611 Gene3D G3DSA:3.10.20.30 4 98 1.1E-22 T 22-04-2016 IPR012675 Beta-grasp domain HRM2_RS19210 0241b8d16edbc70abebe725c3579fd86 611 Pfam PF14574 Domain of unknown function (DUF4445) 194 609 1.2E-134 T 22-04-2016 IPR027980 Protein of unknown function DUF4445 HRM2_RS19210 0241b8d16edbc70abebe725c3579fd86 611 SUPERFAMILY SSF54292 3 95 1.22E-22 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 HRM2_RS07925 7958551684ea483e5eb74a76cbe477da 493 PANTHER PTHR10799 350 488 9.1E-26 T 22-04-2016 HRM2_RS07925 7958551684ea483e5eb74a76cbe477da 493 PANTHER PTHR10799 140 283 9.1E-26 T 22-04-2016 HRM2_RS07925 7958551684ea483e5eb74a76cbe477da 493 Pfam PF02830 V4R domain 202 244 8.4E-8 T 22-04-2016 IPR004096 4-vinyl reductase, 4VR HRM2_RS07925 7958551684ea483e5eb74a76cbe477da 493 SUPERFAMILY SSF111126 162 245 2.72E-13 T 22-04-2016 IPR024096 NO signalling/Golgi transport ligand-binding domain HRM2_RS07925 7958551684ea483e5eb74a76cbe477da 493 SMART SM00267 306 491 4.7E-50 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS07925 7958551684ea483e5eb74a76cbe477da 493 SMART SM00989 185 246 3.1E-5 T 22-04-2016 IPR004096 4-vinyl reductase, 4VR HRM2_RS07925 7958551684ea483e5eb74a76cbe477da 493 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 313 489 7.7E-47 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS07925 7958551684ea483e5eb74a76cbe477da 493 PANTHER PTHR10799:SF750 350 488 9.1E-26 T 22-04-2016 HRM2_RS07925 7958551684ea483e5eb74a76cbe477da 493 PANTHER PTHR10799:SF750 140 283 9.1E-26 T 22-04-2016 HRM2_RS07925 7958551684ea483e5eb74a76cbe477da 493 Pfam PF00990 Diguanylate cyclase, GGDEF domain 318 487 7.4E-39 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS07925 7958551684ea483e5eb74a76cbe477da 493 SUPERFAMILY SSF55073 322 489 1.49E-41 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS07925 7958551684ea483e5eb74a76cbe477da 493 Gene3D G3DSA:3.30.70.270 319 489 5.0E-45 T 22-04-2016 HRM2_RS07925 7958551684ea483e5eb74a76cbe477da 493 Gene3D G3DSA:3.30.1380.20 122 248 3.2E-16 T 22-04-2016 HRM2_RS00850 1989c0017bdcbf84caa600ec5c4431de 266 Gene3D G3DSA:3.40.190.10 30 186 3.0E-29 T 22-04-2016 HRM2_RS00850 1989c0017bdcbf84caa600ec5c4431de 266 SUPERFAMILY SSF53850 28 262 1.81E-48 T 22-04-2016 HRM2_RS00850 1989c0017bdcbf84caa600ec5c4431de 266 PANTHER PTHR30570 4 138 3.2E-21 T 22-04-2016 HRM2_RS00850 1989c0017bdcbf84caa600ec5c4431de 266 PANTHER PTHR30570 154 262 3.2E-21 T 22-04-2016 HRM2_RS00850 1989c0017bdcbf84caa600ec5c4431de 266 Pfam PF12849 PBP superfamily domain 24 262 4.9E-32 T 22-04-2016 IPR024370 PBP domain HRM2_RS03730 332c6068633cc1a4b1dcdfa75bb54c3b 549 Pfam PF13193 AMP-binding enzyme C-terminal domain 459 534 8.7E-21 T 22-04-2016 IPR025110 AMP-binding enzyme C-terminal domain HRM2_RS03730 332c6068633cc1a4b1dcdfa75bb54c3b 549 Gene3D G3DSA:2.30.38.10 368 441 1.1E-16 T 22-04-2016 HRM2_RS03730 332c6068633cc1a4b1dcdfa75bb54c3b 549 PANTHER PTHR24096 14 544 1.7E-163 T 22-04-2016 HRM2_RS03730 332c6068633cc1a4b1dcdfa75bb54c3b 549 Gene3D G3DSA:3.30.300.30 445 544 6.1E-31 T 22-04-2016 HRM2_RS03730 332c6068633cc1a4b1dcdfa75bb54c3b 549 ProSitePatterns PS00455 Putative AMP-binding domain signature. 203 214 - T 22-04-2016 IPR020845 AMP-binding, conserved site HRM2_RS03730 332c6068633cc1a4b1dcdfa75bb54c3b 549 SUPERFAMILY SSF56801 8 547 6.8E-142 T 22-04-2016 HRM2_RS03730 332c6068633cc1a4b1dcdfa75bb54c3b 549 Gene3D G3DSA:3.40.50.980 209 367 4.6E-32 T 22-04-2016 HRM2_RS03730 332c6068633cc1a4b1dcdfa75bb54c3b 549 Gene3D G3DSA:3.40.50.980 39 208 2.6E-40 T 22-04-2016 HRM2_RS03730 332c6068633cc1a4b1dcdfa75bb54c3b 549 Pfam PF00501 AMP-binding enzyme 44 450 1.3E-95 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS03730 332c6068633cc1a4b1dcdfa75bb54c3b 549 PANTHER PTHR24096:SF229 14 544 1.7E-163 T 22-04-2016 HRM2_RS10355 3ebb91b87a79f3b9e2eab4f875d0376a 601 Gene3D G3DSA:2.40.30.10 197 292 1.8E-22 T 22-04-2016 HRM2_RS10355 3ebb91b87a79f3b9e2eab4f875d0376a 601 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 46 61 - T 22-04-2016 IPR031157 Tr-type G domain, conserved site HRM2_RS10355 3ebb91b87a79f3b9e2eab4f875d0376a 601 TIGRFAM TIGR01393 lepA: elongation factor 4 6 599 1.9E-291 T 22-04-2016 IPR006297 Elongation factor 4 GO:0005525 HRM2_RS10355 3ebb91b87a79f3b9e2eab4f875d0376a 601 Hamap MF_00071 Elongation factor 4 [lepA]. 1 601 276.6 T 22-04-2016 IPR006297 Elongation factor 4 GO:0005525 HRM2_RS10355 3ebb91b87a79f3b9e2eab4f875d0376a 601 SUPERFAMILY SSF50447 169 289 2.29E-25 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain HRM2_RS10355 3ebb91b87a79f3b9e2eab4f875d0376a 601 SMART SM00838 405 491 0.0058 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain HRM2_RS10355 3ebb91b87a79f3b9e2eab4f875d0376a 601 PANTHER PTHR23115 4 377 2.4E-273 T 22-04-2016 HRM2_RS10355 3ebb91b87a79f3b9e2eab4f875d0376a 601 Pfam PF03144 Elongation factor Tu domain 2 210 279 2.3E-8 T 22-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 HRM2_RS10355 3ebb91b87a79f3b9e2eab4f875d0376a 601 PANTHER PTHR23115 405 600 2.4E-273 T 22-04-2016 HRM2_RS10355 3ebb91b87a79f3b9e2eab4f875d0376a 601 Gene3D G3DSA:3.30.70.870 295 373 2.2E-24 T 22-04-2016 HRM2_RS10355 3ebb91b87a79f3b9e2eab4f875d0376a 601 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 178 6.8E-18 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HRM2_RS10355 3ebb91b87a79f3b9e2eab4f875d0376a 601 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.7E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS10355 3ebb91b87a79f3b9e2eab4f875d0376a 601 PRINTS PR00315 GTP-binding elongation factor signature 10 23 1.7E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS10355 3ebb91b87a79f3b9e2eab4f875d0376a 601 PRINTS PR00315 GTP-binding elongation factor signature 130 139 1.7E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS10355 3ebb91b87a79f3b9e2eab4f875d0376a 601 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.7E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS10355 3ebb91b87a79f3b9e2eab4f875d0376a 601 PRINTS PR00315 GTP-binding elongation factor signature 53 61 1.7E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HRM2_RS10355 3ebb91b87a79f3b9e2eab4f875d0376a 601 Pfam PF06421 GTP-binding protein LepA C-terminus 492 598 1.1E-48 T 22-04-2016 IPR013842 GTP-binding protein LepA, C-terminal HRM2_RS10355 3ebb91b87a79f3b9e2eab4f875d0376a 601 Pfam PF00009 Elongation factor Tu GTP binding domain 6 185 4.6E-53 T 22-04-2016 HRM2_RS10355 3ebb91b87a79f3b9e2eab4f875d0376a 601 Gene3D G3DSA:3.30.70.240 405 494 1.7E-18 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain HRM2_RS10355 3ebb91b87a79f3b9e2eab4f875d0376a 601 SUPERFAMILY SSF54980 295 374 3.53E-18 T 22-04-2016 IPR009022 Elongation factor G, III-V domain HRM2_RS10355 3ebb91b87a79f3b9e2eab4f875d0376a 601 SUPERFAMILY SSF54980 405 498 1.77E-22 T 22-04-2016 IPR009022 Elongation factor G, III-V domain HRM2_RS10355 3ebb91b87a79f3b9e2eab4f875d0376a 601 Gene3D G3DSA:3.40.50.300 4 196 3.6E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10355 3ebb91b87a79f3b9e2eab4f875d0376a 601 SUPERFAMILY SSF52540 4 203 2.35E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10355 3ebb91b87a79f3b9e2eab4f875d0376a 601 Pfam PF00679 Elongation factor G C-terminus 404 489 4.0E-20 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain HRM2_RS10355 3ebb91b87a79f3b9e2eab4f875d0376a 601 PANTHER PTHR23115:SF97 405 600 2.4E-273 T 22-04-2016 HRM2_RS10355 3ebb91b87a79f3b9e2eab4f875d0376a 601 PANTHER PTHR23115:SF97 4 377 2.4E-273 T 22-04-2016 HRM2_RS16885 05720338ae293c9a971804d0929a732b 242 Pfam PF09335 SNARE associated Golgi protein 84 200 4.1E-17 T 22-04-2016 IPR032816 SNARE associated Golgi protein HRM2_RS21500 044ee8608e900238d0694a65ee3114df 495 PANTHER PTHR21432:SF10 8 491 1.4E-228 T 22-04-2016 HRM2_RS21500 044ee8608e900238d0694a65ee3114df 495 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 321 462 6.2E-41 T 22-04-2016 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain HRM2_RS21500 044ee8608e900238d0694a65ee3114df 495 SUPERFAMILY SSF100950 8 221 6.47E-60 T 22-04-2016 HRM2_RS21500 044ee8608e900238d0694a65ee3114df 495 Gene3D G3DSA:3.40.1080.10 8 219 1.8E-42 T 22-04-2016 HRM2_RS21500 044ee8608e900238d0694a65ee3114df 495 PANTHER PTHR21432 8 491 1.4E-228 T 22-04-2016 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 HRM2_RS21500 044ee8608e900238d0694a65ee3114df 495 SUPERFAMILY SSF100950 225 489 2.68E-73 T 22-04-2016 HRM2_RS21500 044ee8608e900238d0694a65ee3114df 495 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 8 491 8.6E-216 T 22-04-2016 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 HRM2_RS21500 044ee8608e900238d0694a65ee3114df 495 Gene3D G3DSA:3.40.810.20 225 487 1.1E-71 T 22-04-2016 HRM2_RS21500 044ee8608e900238d0694a65ee3114df 495 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 10 214 8.4E-37 T 22-04-2016 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 HRM2_RS04140 70b43724152ab09bf393cc77606f93e8 242 Gene3D G3DSA:1.10.3720.10 17 230 3.4E-43 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS04140 70b43724152ab09bf393cc77606f93e8 242 SUPERFAMILY SSF161098 18 216 3.92E-39 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS04140 70b43724152ab09bf393cc77606f93e8 242 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 20 125 1.3E-19 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HRM2_RS04140 70b43724152ab09bf393cc77606f93e8 242 PANTHER PTHR30614 1 236 1.4E-64 T 22-04-2016 HRM2_RS04140 70b43724152ab09bf393cc77606f93e8 242 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 39 230 7.9E-19 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS06285 76832748c2c11148770c8f5ceee478f8 486 PANTHER PTHR23135 16 469 4.5E-137 T 22-04-2016 HRM2_RS06285 76832748c2c11148770c8f5ceee478f8 486 Pfam PF08245 Mur ligase middle domain 115 309 6.2E-41 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HRM2_RS06285 76832748c2c11148770c8f5ceee478f8 486 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 7 469 31.539 T 22-04-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS06285 76832748c2c11148770c8f5ceee478f8 486 Gene3D G3DSA:3.40.1390.10 5 79 2.0E-19 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 HRM2_RS06285 76832748c2c11148770c8f5ceee478f8 486 SUPERFAMILY SSF63418 10 103 1.19E-18 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 HRM2_RS06285 76832748c2c11148770c8f5ceee478f8 486 PANTHER PTHR23135:SF3 16 469 4.5E-137 T 22-04-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS06285 76832748c2c11148770c8f5ceee478f8 486 SUPERFAMILY SSF53244 330 468 2.52E-32 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HRM2_RS06285 76832748c2c11148770c8f5ceee478f8 486 Pfam PF01225 Mur ligase family, catalytic domain 30 103 6.1E-9 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 HRM2_RS06285 76832748c2c11148770c8f5ceee478f8 486 Gene3D G3DSA:3.40.1190.10 92 327 5.7E-59 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HRM2_RS06285 76832748c2c11148770c8f5ceee478f8 486 Pfam PF02875 Mur ligase family, glutamate ligase domain 330 407 6.8E-13 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HRM2_RS06285 76832748c2c11148770c8f5ceee478f8 486 SUPERFAMILY SSF53623 110 328 1.96E-45 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HRM2_RS06285 76832748c2c11148770c8f5ceee478f8 486 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 34 468 1.6E-117 T 22-04-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS06285 76832748c2c11148770c8f5ceee478f8 486 Gene3D G3DSA:3.90.190.20 330 470 7.9E-39 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HRM2_RS03720 facec2253c1b6067f97cf9c0f7f118e3 184 Pfam PF01965 DJ-1/PfpI family 3 166 2.3E-43 T 22-04-2016 IPR002818 DJ-1/PfpI HRM2_RS03720 facec2253c1b6067f97cf9c0f7f118e3 184 PANTHER PTHR11019 3 170 2.1E-63 T 22-04-2016 HRM2_RS03720 facec2253c1b6067f97cf9c0f7f118e3 184 SUPERFAMILY SSF52317 3 177 2.12E-47 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS03720 facec2253c1b6067f97cf9c0f7f118e3 184 TIGRFAM TIGR01383 not_thiJ: DJ-1 family protein 4 179 1.7E-60 T 22-04-2016 IPR006287 DJ-1 HRM2_RS03720 facec2253c1b6067f97cf9c0f7f118e3 184 Gene3D G3DSA:3.40.50.880 2 181 7.7E-55 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS03720 facec2253c1b6067f97cf9c0f7f118e3 184 PANTHER PTHR11019:SF100 3 170 2.1E-63 T 22-04-2016 HRM2_RS14930 74a8c180bf534d3a7e7b2391b692ec8c 146 PRINTS PR00813 Bacterial general secretion pathway protein G signature 11 36 3.3E-15 T 22-04-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 HRM2_RS14930 74a8c180bf534d3a7e7b2391b692ec8c 146 PRINTS PR00813 Bacterial general secretion pathway protein G signature 47 65 3.3E-15 T 22-04-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 HRM2_RS14930 74a8c180bf534d3a7e7b2391b692ec8c 146 Gene3D G3DSA:3.30.700.10 12 77 8.2E-7 T 22-04-2016 HRM2_RS14930 74a8c180bf534d3a7e7b2391b692ec8c 146 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 10 30 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site HRM2_RS14930 74a8c180bf534d3a7e7b2391b692ec8c 146 Pfam PF08334 Type II secretion system (T2SS), protein G 35 140 3.1E-39 T 22-04-2016 IPR013545 Type II secretion system protein G HRM2_RS14930 74a8c180bf534d3a7e7b2391b692ec8c 146 SUPERFAMILY SSF54523 38 140 8.37E-32 T 22-04-2016 HRM2_RS14930 74a8c180bf534d3a7e7b2391b692ec8c 146 Pfam PF13633 Prokaryotic N-terminal methylation site 9 33 1.3E-9 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site HRM2_RS14930 74a8c180bf534d3a7e7b2391b692ec8c 146 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 10 31 1.5E-8 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site HRM2_RS14930 74a8c180bf534d3a7e7b2391b692ec8c 146 PANTHER PTHR30093:SF9 4 140 1.5E-42 T 22-04-2016 HRM2_RS14930 74a8c180bf534d3a7e7b2391b692ec8c 146 PANTHER PTHR30093 4 140 1.5E-42 T 22-04-2016 HRM2_RS14930 74a8c180bf534d3a7e7b2391b692ec8c 146 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 10 140 1.3E-48 T 22-04-2016 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 HRM2_RS22935 922216dba9af0b5fc673a8ab1a835bb4 240 SUPERFAMILY SSF52540 1 235 3.99E-80 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22935 922216dba9af0b5fc673a8ab1a835bb4 240 SMART SM00382 26 213 1.7E-16 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS22935 922216dba9af0b5fc673a8ab1a835bb4 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS22935 922216dba9af0b5fc673a8ab1a835bb4 240 Gene3D G3DSA:3.40.50.300 1 237 2.7E-82 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22935 922216dba9af0b5fc673a8ab1a835bb4 240 Pfam PF00005 ABC transporter 17 165 2.4E-37 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS22935 922216dba9af0b5fc673a8ab1a835bb4 240 PANTHER PTHR24220 3 240 1.2E-154 T 22-04-2016 HRM2_RS22935 922216dba9af0b5fc673a8ab1a835bb4 240 PANTHER PTHR24220:SF474 3 240 1.2E-154 T 22-04-2016 HRM2_RS22935 922216dba9af0b5fc673a8ab1a835bb4 240 PIRSF PIRSF039085 1 240 2.0E-106 T 22-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 HRM2_RS06665 bbfe8480882b911053966a6affe01c4f 687 SUPERFAMILY SSF56935 446 686 1.69E-97 T 22-04-2016 HRM2_RS06665 bbfe8480882b911053966a6affe01c4f 687 SUPERFAMILY SSF56935 37 417 1.69E-97 T 22-04-2016 HRM2_RS06665 bbfe8480882b911053966a6affe01c4f 687 Pfam PF07715 TonB-dependent Receptor Plug Domain 52 145 1.5E-19 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 HRM2_RS06665 bbfe8480882b911053966a6affe01c4f 687 PANTHER PTHR32552 225 687 8.0E-44 T 22-04-2016 HRM2_RS06665 bbfe8480882b911053966a6affe01c4f 687 PANTHER PTHR32552 1 206 8.0E-44 T 22-04-2016 HRM2_RS06665 bbfe8480882b911053966a6affe01c4f 687 Pfam PF00593 TonB dependent receptor 449 685 1.3E-28 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 HRM2_RS06665 bbfe8480882b911053966a6affe01c4f 687 Gene3D G3DSA:2.170.130.10 27 156 1.4E-26 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 HRM2_RS06665 bbfe8480882b911053966a6affe01c4f 687 Gene3D G3DSA:2.40.170.20 157 685 9.1E-76 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 HRM2_RS20215 e67e03da33cd287db5c7a8c52fd702e4 191 Pfam PF00384 Molybdopterin oxidoreductase 103 145 5.1E-5 T 22-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 HRM2_RS20215 e67e03da33cd287db5c7a8c52fd702e4 191 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 4 23 6.1E-4 T 22-04-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal HRM2_RS20215 e67e03da33cd287db5c7a8c52fd702e4 191 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 44 99 3.9E-15 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS20215 e67e03da33cd287db5c7a8c52fd702e4 191 Gene3D G3DSA:3.40.50.740 105 191 5.7E-15 T 22-04-2016 HRM2_RS20215 e67e03da33cd287db5c7a8c52fd702e4 191 PANTHER PTHR11615:SF126 41 191 8.2E-58 T 22-04-2016 HRM2_RS20215 e67e03da33cd287db5c7a8c52fd702e4 191 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 2 25 5.6E-6 T 22-04-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal HRM2_RS20215 e67e03da33cd287db5c7a8c52fd702e4 191 SUPERFAMILY SSF53706 38 191 9.29E-55 T 22-04-2016 HRM2_RS20215 e67e03da33cd287db5c7a8c52fd702e4 191 Gene3D G3DSA:2.20.25.90 43 104 1.2E-21 T 22-04-2016 HRM2_RS20215 e67e03da33cd287db5c7a8c52fd702e4 191 SMART SM00926 43 100 3.7E-19 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS20215 e67e03da33cd287db5c7a8c52fd702e4 191 PANTHER PTHR11615 41 191 8.2E-58 T 22-04-2016 HRM2_RS05115 59145a6bd4874606971f4f3f6e6ffd1e 195 Pfam PF04264 YceI-like domain 25 191 2.1E-38 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like HRM2_RS05115 59145a6bd4874606971f4f3f6e6ffd1e 195 Gene3D G3DSA:2.40.128.110 24 194 3.5E-48 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like HRM2_RS05115 59145a6bd4874606971f4f3f6e6ffd1e 195 PANTHER PTHR34406 1 192 5.9E-41 T 22-04-2016 HRM2_RS05115 59145a6bd4874606971f4f3f6e6ffd1e 195 SMART SM00867 24 192 2.5E-50 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like HRM2_RS05115 59145a6bd4874606971f4f3f6e6ffd1e 195 SUPERFAMILY SSF101874 24 193 2.35E-46 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like HRM2_RS05115 59145a6bd4874606971f4f3f6e6ffd1e 195 PANTHER PTHR34406:SF1 1 192 5.9E-41 T 22-04-2016 HRM2_RS06990 fa3b27d7e77a062c797d99a916d6c706 219 Gene3D G3DSA:1.10.3720.10 11 210 2.9E-31 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS06990 fa3b27d7e77a062c797d99a916d6c706 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 201 5.0E-14 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS06990 fa3b27d7e77a062c797d99a916d6c706 219 PANTHER PTHR30614 6 216 9.4E-54 T 22-04-2016 HRM2_RS06990 fa3b27d7e77a062c797d99a916d6c706 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 104 3.5E-15 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HRM2_RS06990 fa3b27d7e77a062c797d99a916d6c706 219 SUPERFAMILY SSF161098 13 196 3.4E-30 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS03970 f7d988648e4675179f40318cb08196e4 218 Pfam PF00117 Glutamine amidotransferase class-I 21 202 1.0E-47 T 22-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 HRM2_RS03970 f7d988648e4675179f40318cb08196e4 218 PRINTS PR00096 Glutamine amidotransferase superfamily signature 91 102 4.5E-12 T 22-04-2016 HRM2_RS03970 f7d988648e4675179f40318cb08196e4 218 PRINTS PR00096 Glutamine amidotransferase superfamily signature 64 73 4.5E-12 T 22-04-2016 HRM2_RS03970 f7d988648e4675179f40318cb08196e4 218 PRINTS PR00096 Glutamine amidotransferase superfamily signature 180 193 4.5E-12 T 22-04-2016 HRM2_RS03970 f7d988648e4675179f40318cb08196e4 218 PANTHER PTHR11922:SF7 1 202 3.8E-77 T 22-04-2016 HRM2_RS03970 f7d988648e4675179f40318cb08196e4 218 Gene3D G3DSA:3.40.50.880 18 202 8.9E-58 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS03970 f7d988648e4675179f40318cb08196e4 218 PANTHER PTHR11922 1 202 3.8E-77 T 22-04-2016 HRM2_RS03970 f7d988648e4675179f40318cb08196e4 218 SUPERFAMILY SSF52317 17 202 1.73E-51 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS03970 f7d988648e4675179f40318cb08196e4 218 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 19 202 1.7E-56 T 22-04-2016 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 HRM2_RS03970 f7d988648e4675179f40318cb08196e4 218 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 61 75 5.1E-6 T 22-04-2016 HRM2_RS03970 f7d988648e4675179f40318cb08196e4 218 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 91 107 5.1E-6 T 22-04-2016 HRM2_RS03970 f7d988648e4675179f40318cb08196e4 218 PRINTS PR00097 Anthranilate synthase component II signature 116 124 1.5E-32 T 22-04-2016 HRM2_RS03970 f7d988648e4675179f40318cb08196e4 218 PRINTS PR00097 Anthranilate synthase component II signature 19 33 1.5E-32 T 22-04-2016 HRM2_RS03970 f7d988648e4675179f40318cb08196e4 218 PRINTS PR00097 Anthranilate synthase component II signature 91 102 1.5E-32 T 22-04-2016 HRM2_RS03970 f7d988648e4675179f40318cb08196e4 218 PRINTS PR00097 Anthranilate synthase component II signature 136 148 1.5E-32 T 22-04-2016 HRM2_RS03970 f7d988648e4675179f40318cb08196e4 218 PRINTS PR00097 Anthranilate synthase component II signature 180 193 1.5E-32 T 22-04-2016 HRM2_RS03970 f7d988648e4675179f40318cb08196e4 218 PRINTS PR00097 Anthranilate synthase component II signature 64 73 1.5E-32 T 22-04-2016 HRM2_RS01630 1a6844393e23f2e8082ca452795e4ee6 225 PANTHER PTHR30614 8 221 1.0E-71 T 22-04-2016 HRM2_RS01630 1a6844393e23f2e8082ca452795e4ee6 225 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 110 2.3E-21 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HRM2_RS01630 1a6844393e23f2e8082ca452795e4ee6 225 SUPERFAMILY SSF161098 14 201 1.96E-40 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS01630 1a6844393e23f2e8082ca452795e4ee6 225 Gene3D G3DSA:1.10.3720.10 15 215 3.2E-42 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS01630 1a6844393e23f2e8082ca452795e4ee6 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 203 2.7E-16 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS23360 cac562c2cd6f96299869ba858a2e386a 278 Gene3D G3DSA:1.10.3150.10 11 264 1.0E-53 T 22-04-2016 IPR013976 Metal-dependent hydrolase HDOD HRM2_RS23360 cac562c2cd6f96299869ba858a2e386a 278 SUPERFAMILY SSF109604 12 264 1.93E-50 T 22-04-2016 HRM2_RS23360 cac562c2cd6f96299869ba858a2e386a 278 Pfam PF08668 HDOD domain 22 213 1.6E-39 T 22-04-2016 IPR013976 Metal-dependent hydrolase HDOD HRM2_RS23360 cac562c2cd6f96299869ba858a2e386a 278 PANTHER PTHR33525 12 262 1.7E-35 T 22-04-2016 HRM2_RS23360 cac562c2cd6f96299869ba858a2e386a 278 PANTHER PTHR33525:SF3 12 262 1.7E-35 T 22-04-2016 HRM2_RS19360 94bfee765121725eb07ecebcc264dce4 217 PANTHER PTHR34183 76 217 1.2E-54 T 22-04-2016 HRM2_RS19360 94bfee765121725eb07ecebcc264dce4 217 Pfam PF03330 Lytic transglycolase 119 212 1.1E-24 T 22-04-2016 IPR009009 RlpA-like protein, double-psi beta-barrel domain HRM2_RS19360 94bfee765121725eb07ecebcc264dce4 217 SUPERFAMILY SSF50685 119 215 6.98E-11 T 22-04-2016 IPR009009 RlpA-like protein, double-psi beta-barrel domain HRM2_RS19360 94bfee765121725eb07ecebcc264dce4 217 PANTHER PTHR34183:SF1 76 217 1.2E-54 T 22-04-2016 HRM2_RS19360 94bfee765121725eb07ecebcc264dce4 217 Gene3D G3DSA:2.40.40.10 163 215 7.2E-6 T 22-04-2016 IPR009009 RlpA-like protein, double-psi beta-barrel domain HRM2_RS19360 94bfee765121725eb07ecebcc264dce4 217 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 121 216 6.5E-37 T 22-04-2016 IPR012997 Rare lipoprotein A HRM2_RS07160 b3bef19ce2495926669492f23c651739 684 PANTHER PTHR11615:SF162 1 675 1.4E-205 T 22-04-2016 HRM2_RS07160 b3bef19ce2495926669492f23c651739 684 PANTHER PTHR11615 1 675 1.4E-205 T 22-04-2016 HRM2_RS07160 b3bef19ce2495926669492f23c651739 684 Gene3D G3DSA:3.40.228.10 134 313 2.1E-61 T 22-04-2016 HRM2_RS07160 b3bef19ce2495926669492f23c651739 684 Gene3D G3DSA:2.40.40.20 519 675 2.2E-50 T 22-04-2016 HRM2_RS07160 b3bef19ce2495926669492f23c651739 684 SMART SM00926 3 57 3.0E-19 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS07160 b3bef19ce2495926669492f23c651739 684 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 5 57 1.7E-18 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS07160 b3bef19ce2495926669492f23c651739 684 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 8 672 2.2E-238 T 22-04-2016 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 HRM2_RS07160 b3bef19ce2495926669492f23c651739 684 Gene3D G3DSA:3.40.50.740 62 132 6.3E-83 T 22-04-2016 HRM2_RS07160 b3bef19ce2495926669492f23c651739 684 Gene3D G3DSA:3.40.50.740 369 518 6.3E-83 T 22-04-2016 HRM2_RS07160 b3bef19ce2495926669492f23c651739 684 Gene3D G3DSA:3.40.50.740 314 336 6.3E-83 T 22-04-2016 HRM2_RS07160 b3bef19ce2495926669492f23c651739 684 Pfam PF01568 Molydopterin dinucleotide binding domain 564 670 1.1E-30 T 22-04-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 HRM2_RS07160 b3bef19ce2495926669492f23c651739 684 SUPERFAMILY SSF50692 520 675 3.84E-45 T 22-04-2016 IPR009010 Aspartate decarboxylase-like domain HRM2_RS07160 b3bef19ce2495926669492f23c651739 684 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 427 444 - T 22-04-2016 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 HRM2_RS07160 b3bef19ce2495926669492f23c651739 684 Gene3D G3DSA:2.20.25.90 3 61 4.6E-22 T 22-04-2016 HRM2_RS07160 b3bef19ce2495926669492f23c651739 684 SUPERFAMILY SSF53706 5 566 1.83E-197 T 22-04-2016 HRM2_RS07160 b3bef19ce2495926669492f23c651739 684 Pfam PF00384 Molybdopterin oxidoreductase 60 481 1.9E-88 T 22-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 HRM2_RS20615 b616c95abfefa89279272fb91ab0769e 550 Gene3D G3DSA:3.40.50.980 213 357 3.6E-50 T 22-04-2016 HRM2_RS20615 b616c95abfefa89279272fb91ab0769e 550 ProSitePatterns PS00455 Putative AMP-binding domain signature. 198 209 - T 22-04-2016 IPR020845 AMP-binding, conserved site HRM2_RS20615 b616c95abfefa89279272fb91ab0769e 550 Gene3D G3DSA:3.30.300.30 443 542 1.2E-30 T 22-04-2016 HRM2_RS20615 b616c95abfefa89279272fb91ab0769e 550 Gene3D G3DSA:3.40.50.980 10 212 1.5E-35 T 22-04-2016 HRM2_RS20615 b616c95abfefa89279272fb91ab0769e 550 Pfam PF13193 AMP-binding enzyme C-terminal domain 457 532 3.4E-13 T 22-04-2016 IPR025110 AMP-binding enzyme C-terminal domain HRM2_RS20615 b616c95abfefa89279272fb91ab0769e 550 PANTHER PTHR24095 11 550 3.0E-181 T 22-04-2016 HRM2_RS20615 b616c95abfefa89279272fb91ab0769e 550 Gene3D G3DSA:2.30.38.10 365 439 8.3E-29 T 22-04-2016 HRM2_RS20615 b616c95abfefa89279272fb91ab0769e 550 Pfam PF00501 AMP-binding enzyme 17 448 3.8E-107 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS20615 b616c95abfefa89279272fb91ab0769e 550 SUPERFAMILY SSF56801 9 544 7.85E-153 T 22-04-2016 HRM2_RS17475 be8ca1891f3cf0d0a4d34a348334a8f3 275 PANTHER PTHR33932 125 272 6.8E-34 T 22-04-2016 HRM2_RS17475 be8ca1891f3cf0d0a4d34a348334a8f3 275 PANTHER PTHR33932 38 86 6.8E-34 T 22-04-2016 HRM2_RS17475 be8ca1891f3cf0d0a4d34a348334a8f3 275 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 134 259 2.9E-26 T 22-04-2016 IPR007182 Na+/H+ antiporter MnhB subunit-related protein HRM2_RS17475 be8ca1891f3cf0d0a4d34a348334a8f3 275 PANTHER PTHR33932:SF4 125 272 6.8E-34 T 22-04-2016 HRM2_RS17475 be8ca1891f3cf0d0a4d34a348334a8f3 275 PANTHER PTHR33932:SF4 38 86 6.8E-34 T 22-04-2016 HRM2_RS19820 33f39d71eaf80eda9c1d0ba29b906a77 122 Pfam PF00072 Response regulator receiver domain 7 86 4.5E-10 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS19820 33f39d71eaf80eda9c1d0ba29b906a77 122 SUPERFAMILY SSF52172 4 87 4.13E-14 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS19820 33f39d71eaf80eda9c1d0ba29b906a77 122 Gene3D G3DSA:3.40.50.2300 2 84 2.6E-13 T 22-04-2016 HRM2_RS06775 ec5d47bd090fa6995ef84768a07d2804 220 PANTHER PTHR22789:SF0 1 216 2.3E-83 T 22-04-2016 HRM2_RS06775 ec5d47bd090fa6995ef84768a07d2804 220 Gene3D G3DSA:3.40.225.10 2 211 1.8E-65 T 22-04-2016 IPR001303 Class II aldolase/adducin N-terminal HRM2_RS06775 ec5d47bd090fa6995ef84768a07d2804 220 SMART SM01007 8 184 3.5E-61 T 22-04-2016 IPR001303 Class II aldolase/adducin N-terminal HRM2_RS06775 ec5d47bd090fa6995ef84768a07d2804 220 PANTHER PTHR22789 1 216 2.3E-83 T 22-04-2016 HRM2_RS06775 ec5d47bd090fa6995ef84768a07d2804 220 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 10 182 2.8E-47 T 22-04-2016 IPR001303 Class II aldolase/adducin N-terminal HRM2_RS06775 ec5d47bd090fa6995ef84768a07d2804 220 SUPERFAMILY SSF53639 3 211 5.89E-65 T 22-04-2016 IPR001303 Class II aldolase/adducin N-terminal HRM2_RS17500 47a5ac44a8eeda1bca1fd2f58e076409 658 Pfam PF01136 Peptidase family U32 78 294 2.6E-51 T 22-04-2016 IPR001539 Peptidase U32 GO:0006508|GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- HRM2_RS17500 47a5ac44a8eeda1bca1fd2f58e076409 658 PANTHER PTHR30217 1 258 2.8E-74 T 22-04-2016 HRM2_RS17500 47a5ac44a8eeda1bca1fd2f58e076409 658 PANTHER PTHR30217:SF10 1 258 2.8E-74 T 22-04-2016 HRM2_RS06315 86ef8a2a99a1566431eee5eb52ab2e7b 310 PANTHER PTHR21071:SF4 1 310 5.8E-95 T 22-04-2016 HRM2_RS06315 86ef8a2a99a1566431eee5eb52ab2e7b 310 Gene3D G3DSA:3.30.43.10 18 89 1.0E-23 T 22-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 HRM2_RS06315 86ef8a2a99a1566431eee5eb52ab2e7b 310 Pfam PF01565 FAD binding domain 37 169 6.9E-22 T 22-04-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 HRM2_RS06315 86ef8a2a99a1566431eee5eb52ab2e7b 310 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 24 307 9.0E-54 T 22-04-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS06315 86ef8a2a99a1566431eee5eb52ab2e7b 310 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 310 78.828 T 22-04-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS06315 86ef8a2a99a1566431eee5eb52ab2e7b 310 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 209 307 3.2E-28 T 22-04-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS06315 86ef8a2a99a1566431eee5eb52ab2e7b 310 Gene3D G3DSA:3.90.78.10 234 309 2.9E-28 T 22-04-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS06315 86ef8a2a99a1566431eee5eb52ab2e7b 310 Gene3D G3DSA:3.30.465.10 98 233 8.5E-34 T 22-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 HRM2_RS06315 86ef8a2a99a1566431eee5eb52ab2e7b 310 SUPERFAMILY SSF56194 209 309 1.14E-31 T 22-04-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS06315 86ef8a2a99a1566431eee5eb52ab2e7b 310 PANTHER PTHR21071 1 310 5.8E-95 T 22-04-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS06315 86ef8a2a99a1566431eee5eb52ab2e7b 310 SUPERFAMILY SSF56176 24 214 2.07E-40 T 22-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 HRM2_RS25250 db5cf113bf671f1b5f1dd595b716e9bc 188 Gene3D G3DSA:3.40.50.300 21 179 3.2E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS25250 db5cf113bf671f1b5f1dd595b716e9bc 188 SUPERFAMILY SSF52540 29 174 2.29E-13 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS25250 db5cf113bf671f1b5f1dd595b716e9bc 188 Pfam PF00685 Sulfotransferase domain 24 82 8.6E-8 T 22-04-2016 IPR000863 Sulfotransferase domain GO:0008146 HRM2_RS05480 4d994dc96c6348f822c4818b3a9a004d 218 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 3 216 37.984 T 22-04-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 HRM2_RS05480 4d994dc96c6348f822c4818b3a9a004d 218 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 15 213 7.1E-58 T 22-04-2016 HRM2_RS05480 4d994dc96c6348f822c4818b3a9a004d 218 PANTHER PTHR11579 18 212 3.9E-70 T 22-04-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 HRM2_RS05480 4d994dc96c6348f822c4818b3a9a004d 218 SUPERFAMILY SSF53335 8 211 4.53E-42 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS05480 4d994dc96c6348f822c4818b3a9a004d 218 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 13 214 1.7E-63 T 22-04-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 HRM2_RS05480 4d994dc96c6348f822c4818b3a9a004d 218 Gene3D G3DSA:3.40.50.150 15 214 3.9E-60 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS05480 4d994dc96c6348f822c4818b3a9a004d 218 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 137 152 - T 22-04-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 HRM2_RS02610 7ec7a55992d80cba4723a88b856982fe 575 PANTHER PTHR30038 1 574 1.5E-173 T 22-04-2016 HRM2_RS02610 7ec7a55992d80cba4723a88b856982fe 575 Gene3D G3DSA:3.60.9.10 1 209 1.1E-64 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS02610 7ec7a55992d80cba4723a88b856982fe 575 SUPERFAMILY SSF56228 2 209 2.22E-54 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS02610 7ec7a55992d80cba4723a88b856982fe 575 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 223 557 9.8E-79 T 22-04-2016 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS02610 7ec7a55992d80cba4723a88b856982fe 575 SMART SM00790 1 207 6.4E-80 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS02610 7ec7a55992d80cba4723a88b856982fe 575 SUPERFAMILY SSF48310 214 573 2.09E-98 T 22-04-2016 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS02610 7ec7a55992d80cba4723a88b856982fe 575 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 3 205 2.5E-59 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS02610 7ec7a55992d80cba4723a88b856982fe 575 Gene3D G3DSA:1.10.569.10 244 420 4.8E-54 T 22-04-2016 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 HRM2_RS02610 7ec7a55992d80cba4723a88b856982fe 575 PANTHER PTHR30038:SF0 1 574 1.5E-173 T 22-04-2016 HRM2_RS17955 37cb5814a17a8decdd677df218f4d958 176 ProSitePatterns PS01014 Transcription termination factor nusG signature. 159 168 - T 22-04-2016 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site HRM2_RS17955 37cb5814a17a8decdd677df218f4d958 176 SUPERFAMILY SSF50104 120 176 2.71E-19 T 22-04-2016 IPR008991 Translation protein SH3-like domain HRM2_RS17955 37cb5814a17a8decdd677df218f4d958 176 Gene3D G3DSA:3.30.70.940 4 112 2.6E-42 T 22-04-2016 IPR006645 NusG, N-terminal GO:0006355 HRM2_RS17955 37cb5814a17a8decdd677df218f4d958 176 Pfam PF00467 KOW motif 125 157 2.8E-7 T 22-04-2016 IPR005824 KOW HRM2_RS17955 37cb5814a17a8decdd677df218f4d958 176 SUPERFAMILY SSF82679 3 113 6.15E-38 T 22-04-2016 IPR006645 NusG, N-terminal GO:0006355 HRM2_RS17955 37cb5814a17a8decdd677df218f4d958 176 PRINTS PR00338 Transcription termination factor NUSG signature 134 149 1.3E-19 T 22-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 HRM2_RS17955 37cb5814a17a8decdd677df218f4d958 176 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 1.3E-19 T 22-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 HRM2_RS17955 37cb5814a17a8decdd677df218f4d958 176 PRINTS PR00338 Transcription termination factor NUSG signature 152 168 1.3E-19 T 22-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 HRM2_RS17955 37cb5814a17a8decdd677df218f4d958 176 SMART SM00738 2 110 2.9E-42 T 22-04-2016 IPR006645 NusG, N-terminal GO:0006355 HRM2_RS17955 37cb5814a17a8decdd677df218f4d958 176 Gene3D G3DSA:2.30.30.30 115 176 1.2E-29 T 22-04-2016 IPR014722 Ribosomal protein L2 domain 2 HRM2_RS17955 37cb5814a17a8decdd677df218f4d958 176 Pfam PF02357 Transcription termination factor nusG 4 106 1.2E-26 T 22-04-2016 IPR006645 NusG, N-terminal GO:0006355 HRM2_RS17955 37cb5814a17a8decdd677df218f4d958 176 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 176 6.4E-68 T 22-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 HRM2_RS17955 37cb5814a17a8decdd677df218f4d958 176 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 176 23.398 T 22-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 HRM2_RS17955 37cb5814a17a8decdd677df218f4d958 176 PANTHER PTHR30265 4 176 5.4E-75 T 22-04-2016 HRM2_RS17955 37cb5814a17a8decdd677df218f4d958 176 SMART SM00739 122 149 2.2E-5 T 22-04-2016 IPR005824 KOW HRM2_RS15500 a009a0201e5336d76aff15a72c55918b 394 SUPERFAMILY SSF53383 15 390 1.1E-79 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS15500 a009a0201e5336d76aff15a72c55918b 394 Gene3D G3DSA:3.40.640.10 48 291 3.1E-55 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS15500 a009a0201e5336d76aff15a72c55918b 394 PANTHER PTHR11751 12 391 4.5E-108 T 22-04-2016 HRM2_RS15500 a009a0201e5336d76aff15a72c55918b 394 Gene3D G3DSA:3.90.1150.10 302 392 8.6E-20 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS15500 a009a0201e5336d76aff15a72c55918b 394 PANTHER PTHR11751:SF429 12 391 4.5E-108 T 22-04-2016 HRM2_RS15500 a009a0201e5336d76aff15a72c55918b 394 Pfam PF00155 Aminotransferase class I and II 35 378 2.2E-44 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HRM2_RS03110 e6f80ce0a7f13ceb096538417ff3a437 207 PIRSF PIRSF006324 1 207 1.4E-54 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 HRM2_RS03110 e6f80ce0a7f13ceb096538417ff3a437 207 Pfam PF01810 LysE type translocator 15 206 6.1E-35 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 HRM2_RS03110 e6f80ce0a7f13ceb096538417ff3a437 207 PANTHER PTHR30086 1 206 9.8E-44 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 HRM2_RS23840 4ebbae31fb3fb9a5737c60969c324a4c 302 PANTHER PTHR11228:SF31 2 112 8.4E-12 T 22-04-2016 HRM2_RS23840 4ebbae31fb3fb9a5737c60969c324a4c 302 Gene3D G3DSA:3.20.20.70 10 276 1.5E-19 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS23840 4ebbae31fb3fb9a5737c60969c324a4c 302 SUPERFAMILY SSF102114 9 237 3.92E-19 T 22-04-2016 HRM2_RS23840 4ebbae31fb3fb9a5737c60969c324a4c 302 Pfam PF04055 Radical SAM superfamily 11 114 8.7E-10 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS23840 4ebbae31fb3fb9a5737c60969c324a4c 302 PANTHER PTHR11228 2 112 8.4E-12 T 22-04-2016 HRM2_RS09995 0f699edbd11a18f838e7c15d4ca457d7 254 SUPERFAMILY SSF55729 150 213 7.64E-31 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS09995 0f699edbd11a18f838e7c15d4ca457d7 254 SUPERFAMILY SSF55729 15 119 7.64E-31 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS09995 0f699edbd11a18f838e7c15d4ca457d7 254 TIGRFAM TIGR03694 exosort_acyl: N-acyl amino acid synthase, PEP-CTERM/exosortase system-associated 11 234 5.0E-55 T 22-04-2016 IPR022484 PEP-CTERM/exosortase system-associated acyltransferase, predicted HRM2_RS09995 0f699edbd11a18f838e7c15d4ca457d7 254 Gene3D G3DSA:3.40.630.30 19 121 5.5E-34 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS09995 0f699edbd11a18f838e7c15d4ca457d7 254 Gene3D G3DSA:3.40.630.30 154 213 5.5E-34 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS09995 0f699edbd11a18f838e7c15d4ca457d7 254 Pfam PF13444 Acetyltransferase (GNAT) domain 28 120 1.3E-14 T 22-04-2016 HRM2_RS23925 5bc6c0e10d69f98e8f30e9a557241633 429 Gene3D G3DSA:1.20.1600.10 25 421 3.8E-55 T 22-04-2016 HRM2_RS23925 5bc6c0e10d69f98e8f30e9a557241633 429 SUPERFAMILY SSF56954 4 421 5.36E-67 T 22-04-2016 HRM2_RS23925 5bc6c0e10d69f98e8f30e9a557241633 429 Pfam PF02321 Outer membrane efflux protein 28 211 1.5E-23 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS23925 5bc6c0e10d69f98e8f30e9a557241633 429 Pfam PF02321 Outer membrane efflux protein 241 420 1.3E-22 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS23925 5bc6c0e10d69f98e8f30e9a557241633 429 PANTHER PTHR30026 4 421 2.5E-39 T 22-04-2016 HRM2_RS04405 b414e8df848dcf03894805cbcd6f60ea 317 Pfam PF00561 alpha/beta hydrolase fold 86 190 2.1E-12 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HRM2_RS04405 b414e8df848dcf03894805cbcd6f60ea 317 Gene3D G3DSA:3.40.50.1820 69 304 2.3E-46 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS04405 b414e8df848dcf03894805cbcd6f60ea 317 PANTHER PTHR10992 69 305 3.2E-38 T 22-04-2016 HRM2_RS04405 b414e8df848dcf03894805cbcd6f60ea 317 SUPERFAMILY SSF53474 57 303 3.44E-48 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS05610 4cb819669ca202c85d3abdf9b53158b9 372 PIRSF PIRSF002786 8 370 2.5E-51 T 22-04-2016 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 HRM2_RS05610 4cb819669ca202c85d3abdf9b53158b9 372 SUPERFAMILY SSF158544 114 214 3.14E-15 T 22-04-2016 HRM2_RS05610 4cb819669ca202c85d3abdf9b53158b9 372 Gene3D G3DSA:1.10.40.60 114 215 6.7E-16 T 22-04-2016 HRM2_RS05610 4cb819669ca202c85d3abdf9b53158b9 372 SUPERFAMILY SSF54523 48 113 1.26E-5 T 22-04-2016 HRM2_RS05610 4cb819669ca202c85d3abdf9b53158b9 372 SUPERFAMILY SSF54523 327 356 1.26E-5 T 22-04-2016 HRM2_RS05610 4cb819669ca202c85d3abdf9b53158b9 372 PANTHER PTHR38831:SF1 11 213 3.2E-15 T 22-04-2016 HRM2_RS05610 4cb819669ca202c85d3abdf9b53158b9 372 Pfam PF03934 Type II secretion system (T2SS), protein K 257 358 1.1E-11 T 22-04-2016 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 HRM2_RS05610 4cb819669ca202c85d3abdf9b53158b9 372 Pfam PF03934 Type II secretion system (T2SS), protein K 37 214 4.5E-24 T 22-04-2016 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 HRM2_RS05610 4cb819669ca202c85d3abdf9b53158b9 372 PANTHER PTHR38831 11 213 3.2E-15 T 22-04-2016 HRM2_RS05610 4cb819669ca202c85d3abdf9b53158b9 372 Gene3D G3DSA:3.30.1300.30 328 356 7.9E-5 T 22-04-2016 HRM2_RS05610 4cb819669ca202c85d3abdf9b53158b9 372 Gene3D G3DSA:3.30.1300.30 45 111 7.9E-5 T 22-04-2016 HRM2_RS17560 f1387f4620a98b9c5b0c4245c06a4f9a 407 SUPERFAMILY SSF160246 55 110 8.89E-6 T 22-04-2016 HRM2_RS17560 f1387f4620a98b9c5b0c4245c06a4f9a 407 PANTHER PTHR36304 110 235 1.7E-27 T 22-04-2016 HRM2_RS17560 f1387f4620a98b9c5b0c4245c06a4f9a 407 PANTHER PTHR36304 2 55 1.7E-27 T 22-04-2016 HRM2_RS17560 f1387f4620a98b9c5b0c4245c06a4f9a 407 PANTHER PTHR36304:SF1 110 235 1.7E-27 T 22-04-2016 HRM2_RS17560 f1387f4620a98b9c5b0c4245c06a4f9a 407 PANTHER PTHR36304:SF1 2 55 1.7E-27 T 22-04-2016 HRM2_RS17560 f1387f4620a98b9c5b0c4245c06a4f9a 407 Pfam PF14332 Domain of unknown function (DUF4388) 4 158 3.5E-21 T 22-04-2016 IPR025497 Domain of unknown function DUF4388 HRM2_RS16945 fb959ba67c2f8aec959a9b827202cc55 220 SUPERFAMILY SSF47644 6 83 1.7E-10 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain HRM2_RS16945 fb959ba67c2f8aec959a9b827202cc55 220 SUPERFAMILY SSF52242 94 217 5.49E-34 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS16945 fb959ba67c2f8aec959a9b827202cc55 220 Pfam PF02607 B12 binding domain 11 83 1.2E-8 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain HRM2_RS16945 fb959ba67c2f8aec959a9b827202cc55 220 Gene3D G3DSA:1.10.1240.10 7 84 1.0E-8 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain HRM2_RS16945 fb959ba67c2f8aec959a9b827202cc55 220 Pfam PF02310 B12 binding domain 98 206 2.8E-16 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS16945 fb959ba67c2f8aec959a9b827202cc55 220 Gene3D G3DSA:3.40.50.280 92 218 1.2E-37 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS13210 d8e36e968badd33cec14b4f878d435c0 229 PANTHER PTHR30098 1 211 1.8E-71 T 22-04-2016 HRM2_RS13210 d8e36e968badd33cec14b4f878d435c0 229 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 32 203 8.4E-70 T 22-04-2016 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 HRM2_RS13210 d8e36e968badd33cec14b4f878d435c0 229 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 33 216 8.2E-65 T 22-04-2016 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 HRM2_RS13210 d8e36e968badd33cec14b4f878d435c0 229 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 229 88.148 T 22-04-2016 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 HRM2_RS13210 d8e36e968badd33cec14b4f878d435c0 229 SUPERFAMILY SSF55729 3 225 1.59E-85 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS14965 e97c8404c1f06c2620660aa47503f3f9 475 Pfam PF02127 Aminopeptidase I zinc metalloprotease (M18) 42 474 1.5E-85 T 22-04-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 HRM2_RS14965 e97c8404c1f06c2620660aa47503f3f9 475 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 300 318 3.8E-29 T 22-04-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 HRM2_RS14965 e97c8404c1f06c2620660aa47503f3f9 475 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 175 192 3.8E-29 T 22-04-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 HRM2_RS14965 e97c8404c1f06c2620660aa47503f3f9 475 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 441 456 3.8E-29 T 22-04-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 HRM2_RS14965 e97c8404c1f06c2620660aa47503f3f9 475 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 139 159 3.8E-29 T 22-04-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 HRM2_RS14965 e97c8404c1f06c2620660aa47503f3f9 475 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 106 122 3.8E-29 T 22-04-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 HRM2_RS14965 e97c8404c1f06c2620660aa47503f3f9 475 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 347 363 3.8E-29 T 22-04-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 HRM2_RS14965 e97c8404c1f06c2620660aa47503f3f9 475 Gene3D G3DSA:3.40.630.10 34 116 5.4E-76 T 22-04-2016 HRM2_RS14965 e97c8404c1f06c2620660aa47503f3f9 475 Gene3D G3DSA:3.40.630.10 260 474 5.4E-76 T 22-04-2016 HRM2_RS14965 e97c8404c1f06c2620660aa47503f3f9 475 SUPERFAMILY SSF53187 20 117 7.61E-91 T 22-04-2016 HRM2_RS14965 e97c8404c1f06c2620660aa47503f3f9 475 SUPERFAMILY SSF53187 251 474 7.61E-91 T 22-04-2016 HRM2_RS14965 e97c8404c1f06c2620660aa47503f3f9 475 Gene3D G3DSA:2.30.250.10 117 254 4.3E-43 T 22-04-2016 IPR023358 Peptidase M18, domain 2 GO:0004177 HRM2_RS14965 e97c8404c1f06c2620660aa47503f3f9 475 PANTHER PTHR28570 6 473 3.3E-179 T 22-04-2016 HRM2_RS14965 e97c8404c1f06c2620660aa47503f3f9 475 SUPERFAMILY SSF101821 118 250 5.77E-33 T 22-04-2016 HRM2_RS14965 e97c8404c1f06c2620660aa47503f3f9 475 PANTHER PTHR28570:SF2 6 473 3.3E-179 T 22-04-2016 HRM2_RS12530 8cfce24d2d03f8953ff622ff05e82d62 81 Pfam PF01583 Adenylylsulphate kinase 13 61 6.4E-18 T 22-04-2016 HRM2_RS12530 8cfce24d2d03f8953ff622ff05e82d62 81 PANTHER PTHR11055 15 81 1.4E-25 T 22-04-2016 HRM2_RS12530 8cfce24d2d03f8953ff622ff05e82d62 81 SUPERFAMILY SSF52540 11 77 1.34E-10 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12530 8cfce24d2d03f8953ff622ff05e82d62 81 Gene3D G3DSA:3.40.50.300 11 81 1.2E-24 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11975 06ee0894171d294c09a3e6489ae93ca8 194 SUPERFAMILY SSF48150 3 186 1.41E-82 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 HRM2_RS11975 06ee0894171d294c09a3e6489ae93ca8 194 Pfam PF03352 Methyladenine glycosylase 7 183 1.0E-81 T 22-04-2016 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 HRM2_RS11975 06ee0894171d294c09a3e6489ae93ca8 194 PANTHER PTHR30037 1 192 5.0E-114 T 22-04-2016 HRM2_RS11975 06ee0894171d294c09a3e6489ae93ca8 194 Gene3D G3DSA:1.10.340.30 3 183 2.4E-83 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 HRM2_RS11975 06ee0894171d294c09a3e6489ae93ca8 194 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 4 182 7.9E-75 T 22-04-2016 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 HRM2_RS11975 06ee0894171d294c09a3e6489ae93ca8 194 PANTHER PTHR30037:SF4 1 192 5.0E-114 T 22-04-2016 HRM2_RS02975 741020200e96ee172f4465462c671118 251 SUPERFAMILY SSF56219 6 246 1.7E-28 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase HRM2_RS02975 741020200e96ee172f4465462c671118 251 PANTHER PTHR14859:SF0 3 250 3.5E-19 T 22-04-2016 HRM2_RS02975 741020200e96ee172f4465462c671118 251 Gene3D G3DSA:3.60.10.10 30 182 1.0E-10 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase HRM2_RS02975 741020200e96ee172f4465462c671118 251 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 36 238 3.3E-13 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase HRM2_RS02975 741020200e96ee172f4465462c671118 251 PANTHER PTHR14859 3 250 3.5E-19 T 22-04-2016 IPR027317 PGAP2-interacting protein HRM2_RS09920 7289c11e1eafdf71a1da5f35638f9a0f 334 Pfam PF01522 Polysaccharide deacetylase 42 164 5.1E-8 T 22-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 HRM2_RS09920 7289c11e1eafdf71a1da5f35638f9a0f 334 SUPERFAMILY SSF88713 36 288 8.06E-21 T 22-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 HRM2_RS09920 7289c11e1eafdf71a1da5f35638f9a0f 334 Gene3D G3DSA:3.20.20.370 32 296 7.4E-16 T 22-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 HRM2_RS11250 eefe027d26c7366d4ccae607d5cf6fd1 328 Pfam PF00676 Dehydrogenase E1 component 17 312 3.0E-76 T 22-04-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 HRM2_RS11250 eefe027d26c7366d4ccae607d5cf6fd1 328 Gene3D G3DSA:3.40.50.970 4 325 9.7E-115 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS11250 eefe027d26c7366d4ccae607d5cf6fd1 328 SUPERFAMILY SSF52518 4 324 3.14E-88 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS11250 eefe027d26c7366d4ccae607d5cf6fd1 328 PANTHER PTHR11516 1 325 6.0E-111 T 22-04-2016 HRM2_RS11250 eefe027d26c7366d4ccae607d5cf6fd1 328 PANTHER PTHR11516:SF25 1 325 6.0E-111 T 22-04-2016 HRM2_RS07210 602e3610bbfb52aaa2ef835a7a37a6b9 228 PANTHER PTHR24220 6 187 8.1E-59 T 22-04-2016 HRM2_RS07210 602e3610bbfb52aaa2ef835a7a37a6b9 228 Pfam PF00005 ABC transporter 25 173 1.0E-29 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS07210 602e3610bbfb52aaa2ef835a7a37a6b9 228 SMART SM00382 34 224 1.2E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS07210 602e3610bbfb52aaa2ef835a7a37a6b9 228 SUPERFAMILY SSF52540 5 205 1.34E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07210 602e3610bbfb52aaa2ef835a7a37a6b9 228 Gene3D G3DSA:3.40.50.300 4 204 2.0E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18810 bf99cf3c66ece44267b59dd136387a36 597 PRINTS PR00344 Bacterial sensor protein C-terminal signature 565 578 6.3E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS18810 bf99cf3c66ece44267b59dd136387a36 597 PRINTS PR00344 Bacterial sensor protein C-terminal signature 541 559 6.3E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS18810 bf99cf3c66ece44267b59dd136387a36 597 PRINTS PR00344 Bacterial sensor protein C-terminal signature 528 538 6.3E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS18810 bf99cf3c66ece44267b59dd136387a36 597 PRINTS PR00344 Bacterial sensor protein C-terminal signature 510 524 6.3E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS18810 bf99cf3c66ece44267b59dd136387a36 597 Gene3D G3DSA:3.30.565.10 416 583 8.7E-42 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS18810 bf99cf3c66ece44267b59dd136387a36 597 SUPERFAMILY SSF55874 420 579 1.57E-40 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS18810 bf99cf3c66ece44267b59dd136387a36 597 Pfam PF00512 His Kinase A (phospho-acceptor) domain 358 428 6.6E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS18810 bf99cf3c66ece44267b59dd136387a36 597 PANTHER PTHR24423 259 283 3.1E-65 T 22-04-2016 HRM2_RS18810 bf99cf3c66ece44267b59dd136387a36 597 PANTHER PTHR24423 334 579 3.1E-65 T 22-04-2016 HRM2_RS18810 bf99cf3c66ece44267b59dd136387a36 597 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 474 580 1.7E-21 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS18810 bf99cf3c66ece44267b59dd136387a36 597 Gene3D G3DSA:1.10.287.130 355 415 3.2E-5 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS18810 bf99cf3c66ece44267b59dd136387a36 597 SMART SM00388 357 430 2.9E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS18810 bf99cf3c66ece44267b59dd136387a36 597 PANTHER PTHR24423:SF458 259 283 3.1E-65 T 22-04-2016 HRM2_RS18810 bf99cf3c66ece44267b59dd136387a36 597 PANTHER PTHR24423:SF458 334 579 3.1E-65 T 22-04-2016 HRM2_RS18810 bf99cf3c66ece44267b59dd136387a36 597 SMART SM00387 473 581 2.6E-30 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS18810 bf99cf3c66ece44267b59dd136387a36 597 SUPERFAMILY SSF47384 353 428 3.14E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS23545 abe0e436e697b86d62e81a68406cc8e4 324 SUPERFAMILY SSF52922 188 322 1.05E-42 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HRM2_RS23545 abe0e436e697b86d62e81a68406cc8e4 324 Pfam PF02779 Transketolase, pyrimidine binding domain 5 178 1.6E-51 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain HRM2_RS23545 abe0e436e697b86d62e81a68406cc8e4 324 SMART SM00861 4 179 3.0E-72 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain HRM2_RS23545 abe0e436e697b86d62e81a68406cc8e4 324 Gene3D G3DSA:3.40.50.920 194 322 2.6E-47 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HRM2_RS23545 abe0e436e697b86d62e81a68406cc8e4 324 Gene3D G3DSA:3.40.50.970 2 193 1.9E-88 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS23545 abe0e436e697b86d62e81a68406cc8e4 324 PANTHER PTHR11624 1 322 3.8E-162 T 22-04-2016 IPR033247 Transketolase family HRM2_RS23545 abe0e436e697b86d62e81a68406cc8e4 324 SUPERFAMILY SSF52518 3 191 1.34E-73 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS23545 abe0e436e697b86d62e81a68406cc8e4 324 PANTHER PTHR11624:SF78 1 322 3.8E-162 T 22-04-2016 HRM2_RS23545 abe0e436e697b86d62e81a68406cc8e4 324 Pfam PF02780 Transketolase, C-terminal domain 193 315 1.0E-42 T 22-04-2016 IPR033248 Transketolase, C-terminal domain HRM2_RS17400 a3fc978fab94830328c15b0be56ca18d 617 Gene3D G3DSA:3.40.710.10 241 604 2.3E-113 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HRM2_RS17400 a3fc978fab94830328c15b0be56ca18d 617 Gene3D G3DSA:3.90.1310.10 121 240 1.4E-31 T 22-04-2016 HRM2_RS17400 a3fc978fab94830328c15b0be56ca18d 617 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 11 600 4.5E-221 T 22-04-2016 IPR017790 Penicillin-binding protein 2 GO:0016020 UniPathway: UPA00219 HRM2_RS17400 a3fc978fab94830328c15b0be56ca18d 617 PANTHER PTHR30627:SF2 9 610 8.9E-217 T 22-04-2016 HRM2_RS17400 a3fc978fab94830328c15b0be56ca18d 617 SUPERFAMILY SSF56519 48 241 2.75E-46 T 22-04-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 HRM2_RS17400 a3fc978fab94830328c15b0be56ca18d 617 Pfam PF00905 Penicillin binding protein transpeptidase domain 259 595 7.4E-80 T 22-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 HRM2_RS17400 a3fc978fab94830328c15b0be56ca18d 617 PANTHER PTHR30627 9 610 8.9E-217 T 22-04-2016 HRM2_RS17400 a3fc978fab94830328c15b0be56ca18d 617 SUPERFAMILY SSF56601 242 605 5.29E-102 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HRM2_RS17400 a3fc978fab94830328c15b0be56ca18d 617 Pfam PF03717 Penicillin-binding Protein dimerisation domain 56 226 2.5E-42 T 22-04-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 HRM2_RS25065 5d4d838a6440d3ad85a736dd5e33ed74 614 SUPERFAMILY SSF55781 126 284 1.92E-15 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS25065 5d4d838a6440d3ad85a736dd5e33ed74 614 PRINTS PR00344 Bacterial sensor protein C-terminal signature 550 560 2.1E-9 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25065 5d4d838a6440d3ad85a736dd5e33ed74 614 PRINTS PR00344 Bacterial sensor protein C-terminal signature 561 579 2.1E-9 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25065 5d4d838a6440d3ad85a736dd5e33ed74 614 PRINTS PR00344 Bacterial sensor protein C-terminal signature 532 546 2.1E-9 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25065 5d4d838a6440d3ad85a736dd5e33ed74 614 PRINTS PR00344 Bacterial sensor protein C-terminal signature 586 599 2.1E-9 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25065 5d4d838a6440d3ad85a736dd5e33ed74 614 Gene3D G3DSA:3.30.450.40 111 297 1.6E-13 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS25065 5d4d838a6440d3ad85a736dd5e33ed74 614 SUPERFAMILY SSF55874 443 604 2.88E-28 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25065 5d4d838a6440d3ad85a736dd5e33ed74 614 SMART SM00065 135 291 6.5E-10 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS25065 5d4d838a6440d3ad85a736dd5e33ed74 614 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 492 599 8.6E-11 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25065 5d4d838a6440d3ad85a736dd5e33ed74 614 Gene3D G3DSA:3.30.565.10 451 600 6.4E-28 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25065 5d4d838a6440d3ad85a736dd5e33ed74 614 Pfam PF01590 GAF domain 138 280 5.3E-8 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS25065 5d4d838a6440d3ad85a736dd5e33ed74 614 SUPERFAMILY SSF158472 68 114 4.97E-11 T 22-04-2016 HRM2_RS25065 5d4d838a6440d3ad85a736dd5e33ed74 614 PANTHER PTHR24423 335 365 1.8E-21 T 22-04-2016 HRM2_RS25065 5d4d838a6440d3ad85a736dd5e33ed74 614 PANTHER PTHR24423 421 614 1.8E-21 T 22-04-2016 HRM2_RS25065 5d4d838a6440d3ad85a736dd5e33ed74 614 PANTHER PTHR24423 70 116 1.8E-21 T 22-04-2016 HRM2_RS25065 5d4d838a6440d3ad85a736dd5e33ed74 614 Pfam PF00672 HAMP domain 47 113 2.3E-14 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS25065 5d4d838a6440d3ad85a736dd5e33ed74 614 SMART SM00387 490 602 3.5E-18 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25065 5d4d838a6440d3ad85a736dd5e33ed74 614 SMART SM00304 66 118 4.8E-11 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS20435 af297fe3516984cf02715009252575ce 125 Pfam PF00512 His Kinase A (phospho-acceptor) domain 3 93 4.0E-13 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS20435 af297fe3516984cf02715009252575ce 125 PANTHER PTHR24423 1 31 2.1E-15 T 22-04-2016 HRM2_RS20435 af297fe3516984cf02715009252575ce 125 PANTHER PTHR24423 57 125 2.1E-15 T 22-04-2016 HRM2_RS20435 af297fe3516984cf02715009252575ce 125 PANTHER PTHR24423:SF497 1 31 2.1E-15 T 22-04-2016 HRM2_RS20435 af297fe3516984cf02715009252575ce 125 PANTHER PTHR24423:SF497 57 125 2.1E-15 T 22-04-2016 HRM2_RS20435 af297fe3516984cf02715009252575ce 125 Gene3D G3DSA:1.10.287.130 7 89 8.2E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS20435 af297fe3516984cf02715009252575ce 125 SUPERFAMILY SSF47384 4 94 2.35E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS20435 af297fe3516984cf02715009252575ce 125 SMART SM00388 3 93 4.1E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS16465 721fb46f8902730a7aa16232cfa6dc51 413 SUPERFAMILY SSF82689 252 353 3.66E-20 T 22-04-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 HRM2_RS16465 721fb46f8902730a7aa16232cfa6dc51 413 PANTHER PTHR30460 9 374 1.6E-66 T 22-04-2016 HRM2_RS16465 721fb46f8902730a7aa16232cfa6dc51 413 SUPERFAMILY SSF50182 189 252 7.52E-11 T 22-04-2016 IPR010920 LSM domain HRM2_RS16465 721fb46f8902730a7aa16232cfa6dc51 413 Pfam PF00924 Mechanosensitive ion channel 146 343 5.0E-39 T 22-04-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 HRM2_RS16465 721fb46f8902730a7aa16232cfa6dc51 413 Gene3D G3DSA:2.30.30.60 205 251 4.0E-10 T 22-04-2016 HRM2_RS16465 721fb46f8902730a7aa16232cfa6dc51 413 SUPERFAMILY SSF82861 95 187 5.75E-14 T 22-04-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 HRM2_RS16465 721fb46f8902730a7aa16232cfa6dc51 413 Gene3D G3DSA:3.30.70.100 258 341 1.6E-11 T 22-04-2016 HRM2_RS00135 8f67f36089777332e032974fba9f7988 252 PANTHER PTHR36529 1 52 5.4E-30 T 22-04-2016 HRM2_RS00135 8f67f36089777332e032974fba9f7988 252 PANTHER PTHR36529 82 245 5.4E-30 T 22-04-2016 HRM2_RS00135 8f67f36089777332e032974fba9f7988 252 Gene3D G3DSA:3.90.550.10 96 218 1.4E-17 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS00135 8f67f36089777332e032974fba9f7988 252 Gene3D G3DSA:3.90.550.10 15 62 1.4E-17 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS00135 8f67f36089777332e032974fba9f7988 252 Pfam PF09837 Uncharacterized protein conserved in bacteria (DUF2064) 103 200 1.8E-24 T 22-04-2016 IPR018641 Transferase 1, rSAM/selenodomain-associated HRM2_RS00135 8f67f36089777332e032974fba9f7988 252 SUPERFAMILY SSF53448 112 238 2.93E-27 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS00135 8f67f36089777332e032974fba9f7988 252 SUPERFAMILY SSF53448 15 77 2.93E-27 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS12185 66dbd8738cfc78ccdde3844d7239ccba 874 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 262 272 1.9E-8 T 22-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 HRM2_RS12185 66dbd8738cfc78ccdde3844d7239ccba 874 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 298 313 1.9E-8 T 22-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 HRM2_RS12185 66dbd8738cfc78ccdde3844d7239ccba 874 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 180 195 1.9E-8 T 22-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 HRM2_RS12185 66dbd8738cfc78ccdde3844d7239ccba 874 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 317 329 1.9E-8 T 22-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 HRM2_RS12185 66dbd8738cfc78ccdde3844d7239ccba 874 Gene3D G3DSA:1.10.390.10 312 454 3.2E-31 T 22-04-2016 HRM2_RS12185 66dbd8738cfc78ccdde3844d7239ccba 874 SUPERFAMILY SSF63737 5 197 3.14E-40 T 22-04-2016 HRM2_RS12185 66dbd8738cfc78ccdde3844d7239ccba 874 SUPERFAMILY SSF55486 211 453 4.98E-74 T 22-04-2016 HRM2_RS12185 66dbd8738cfc78ccdde3844d7239ccba 874 Pfam PF01433 Peptidase family M1 93 388 6.5E-65 T 22-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 HRM2_RS12185 66dbd8738cfc78ccdde3844d7239ccba 874 Pfam PF11940 Domain of unknown function (DUF3458) 463 828 3.7E-125 T 22-04-2016 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal HRM2_RS12185 66dbd8738cfc78ccdde3844d7239ccba 874 Gene3D G3DSA:1.25.50.10 545 870 1.0E-112 T 22-04-2016 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal HRM2_RS12185 66dbd8738cfc78ccdde3844d7239ccba 874 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 11 870 0.0 T 22-04-2016 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 HRM2_RS12185 66dbd8738cfc78ccdde3844d7239ccba 874 PANTHER PTHR11533:SF152 609 874 0.0 T 22-04-2016 HRM2_RS12185 66dbd8738cfc78ccdde3844d7239ccba 874 PANTHER PTHR11533:SF152 8 584 0.0 T 22-04-2016 HRM2_RS12185 66dbd8738cfc78ccdde3844d7239ccba 874 PANTHER PTHR11533 609 874 0.0 T 22-04-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 HRM2_RS12185 66dbd8738cfc78ccdde3844d7239ccba 874 PANTHER PTHR11533 8 584 0.0 T 22-04-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 HRM2_RS02130 16c4da6c43e9737a5bef15b8185a7b4b 250 Gene3D G3DSA:3.40.50.300 3 205 4.7E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02130 16c4da6c43e9737a5bef15b8185a7b4b 250 SMART SM00382 26 207 7.2E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS02130 16c4da6c43e9737a5bef15b8185a7b4b 250 PANTHER PTHR24220 3 218 8.9E-77 T 22-04-2016 HRM2_RS02130 16c4da6c43e9737a5bef15b8185a7b4b 250 SUPERFAMILY SSF52540 2 232 1.62E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02130 16c4da6c43e9737a5bef15b8185a7b4b 250 PANTHER PTHR24220:SF14 3 218 8.9E-77 T 22-04-2016 HRM2_RS02130 16c4da6c43e9737a5bef15b8185a7b4b 250 Pfam PF00005 ABC transporter 18 158 3.2E-24 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS24470 8214be6511ced5be43b0e8ddbbeccedc 273 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 190 273 3.7E-15 T 22-04-2016 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS24470 8214be6511ced5be43b0e8ddbbeccedc 273 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 273 9.9E-55 T 22-04-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS24470 8214be6511ced5be43b0e8ddbbeccedc 273 SUPERFAMILY SSF55979 190 273 2.46E-17 T 22-04-2016 HRM2_RS24470 8214be6511ced5be43b0e8ddbbeccedc 273 PANTHER PTHR30478 1 273 1.2E-53 T 22-04-2016 HRM2_RS24470 8214be6511ced5be43b0e8ddbbeccedc 273 SUPERFAMILY SSF55979 2 58 4.13E-5 T 22-04-2016 HRM2_RS24470 8214be6511ced5be43b0e8ddbbeccedc 273 SMART SM00480 1 273 2.2E-10 T 22-04-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS24470 8214be6511ced5be43b0e8ddbbeccedc 273 Pfam PF02767 DNA polymerase III beta subunit, central domain 69 188 4.3E-16 T 22-04-2016 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS24470 8214be6511ced5be43b0e8ddbbeccedc 273 Gene3D G3DSA:3.10.150.10 196 273 1.5E-17 T 22-04-2016 HRM2_RS24470 8214be6511ced5be43b0e8ddbbeccedc 273 Gene3D G3DSA:3.10.150.10 67 193 6.6E-20 T 22-04-2016 HRM2_RS24470 8214be6511ced5be43b0e8ddbbeccedc 273 SUPERFAMILY SSF55979 68 192 2.45E-12 T 22-04-2016 HRM2_RS12820 6f585173196ba46cd8cef6c6a7dee8a1 295 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 16 293 1.1E-79 T 22-04-2016 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 HRM2_RS12820 6f585173196ba46cd8cef6c6a7dee8a1 295 Gene3D G3DSA:3.30.470.20 119 248 3.5E-55 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS12820 6f585173196ba46cd8cef6c6a7dee8a1 295 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 13 293 28.103 T 22-04-2016 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 HRM2_RS12820 6f585173196ba46cd8cef6c6a7dee8a1 295 ProSitePatterns PS01058 SAICAR synthetase signature 2. 206 214 - T 22-04-2016 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 HRM2_RS12820 6f585173196ba46cd8cef6c6a7dee8a1 295 PANTHER PTHR11609:SF6 11 293 4.5E-115 T 22-04-2016 HRM2_RS12820 6f585173196ba46cd8cef6c6a7dee8a1 295 PANTHER PTHR11609 11 293 4.5E-115 T 22-04-2016 HRM2_RS12820 6f585173196ba46cd8cef6c6a7dee8a1 295 ProSitePatterns PS01057 SAICAR synthetase signature 1. 107 121 - T 22-04-2016 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 HRM2_RS12820 6f585173196ba46cd8cef6c6a7dee8a1 295 Gene3D G3DSA:3.30.200.20 4 118 3.1E-44 T 22-04-2016 HRM2_RS12820 6f585173196ba46cd8cef6c6a7dee8a1 295 Pfam PF01259 SAICAR synthetase 15 268 3.8E-101 T 22-04-2016 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 HRM2_RS12820 6f585173196ba46cd8cef6c6a7dee8a1 295 SUPERFAMILY SSF56104 5 295 1.14E-106 T 22-04-2016 HRM2_RS16155 416176a5a6ea09c91a6506c116d9b886 568 Gene3D G3DSA:3.40.250.10 467 557 8.4E-11 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS16155 416176a5a6ea09c91a6506c116d9b886 568 Gene3D G3DSA:3.30.390.30 348 460 2.1E-25 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HRM2_RS16155 416176a5a6ea09c91a6506c116d9b886 568 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 343 447 5.8E-11 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HRM2_RS16155 416176a5a6ea09c91a6506c116d9b886 568 SUPERFAMILY SSF55424 335 458 7.04E-24 T 22-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 HRM2_RS16155 416176a5a6ea09c91a6506c116d9b886 568 Gene3D G3DSA:3.50.50.60 1 117 5.5E-18 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS16155 416176a5a6ea09c91a6506c116d9b886 568 PANTHER PTHR22912 1 455 5.6E-124 T 22-04-2016 HRM2_RS16155 416176a5a6ea09c91a6506c116d9b886 568 SUPERFAMILY SSF51905 2 177 3.09E-41 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS16155 416176a5a6ea09c91a6506c116d9b886 568 SUPERFAMILY SSF51905 208 358 3.09E-41 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS16155 416176a5a6ea09c91a6506c116d9b886 568 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 247 263 4.4E-21 T 22-04-2016 HRM2_RS16155 416176a5a6ea09c91a6506c116d9b886 568 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 160 178 4.4E-21 T 22-04-2016 HRM2_RS16155 416176a5a6ea09c91a6506c116d9b886 568 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 4.4E-21 T 22-04-2016 HRM2_RS16155 416176a5a6ea09c91a6506c116d9b886 568 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 113 131 4.4E-21 T 22-04-2016 HRM2_RS16155 416176a5a6ea09c91a6506c116d9b886 568 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 274 296 4.4E-21 T 22-04-2016 HRM2_RS16155 416176a5a6ea09c91a6506c116d9b886 568 Gene3D G3DSA:3.50.50.60 118 328 7.8E-51 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS16155 416176a5a6ea09c91a6506c116d9b886 568 SUPERFAMILY SSF52821 460 559 2.2E-12 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS16155 416176a5a6ea09c91a6506c116d9b886 568 PANTHER PTHR22912:SF140 1 455 5.6E-124 T 22-04-2016 HRM2_RS16155 416176a5a6ea09c91a6506c116d9b886 568 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 302 5.7E-60 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS01345 013995886d8ec0c4176de869f55805ee 235 Pfam PF00005 ABC transporter 17 162 6.7E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS01345 013995886d8ec0c4176de869f55805ee 235 SMART SM00382 26 212 1.4E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS01345 013995886d8ec0c4176de869f55805ee 235 PANTHER PTHR24220 3 235 3.8E-132 T 22-04-2016 HRM2_RS01345 013995886d8ec0c4176de869f55805ee 235 Gene3D G3DSA:3.40.50.300 1 232 1.2E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01345 013995886d8ec0c4176de869f55805ee 235 SUPERFAMILY SSF52540 2 233 1.85E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01345 013995886d8ec0c4176de869f55805ee 235 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS01345 013995886d8ec0c4176de869f55805ee 235 PIRSF PIRSF039137 1 235 4.0E-110 T 22-04-2016 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 HRM2_RS01345 013995886d8ec0c4176de869f55805ee 235 PANTHER PTHR24220:SF568 3 235 3.8E-132 T 22-04-2016 HRM2_RS19555 0c9ca33bdecd4c6282ed2e0458f58210 267 PIRSF PIRSF006157 4 267 4.6E-84 T 22-04-2016 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA type GO:0008270|GO:0016701|GO:0055114 HRM2_RS19555 0c9ca33bdecd4c6282ed2e0458f58210 267 PANTHER PTHR30096 9 254 2.8E-86 T 22-04-2016 HRM2_RS19555 0c9ca33bdecd4c6282ed2e0458f58210 267 PANTHER PTHR30096:SF0 9 254 2.8E-86 T 22-04-2016 HRM2_RS19555 0c9ca33bdecd4c6282ed2e0458f58210 267 Gene3D G3DSA:3.40.830.10 4 247 1.6E-85 T 22-04-2016 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 HRM2_RS19555 0c9ca33bdecd4c6282ed2e0458f58210 267 SUPERFAMILY SSF53213 11 249 8.76E-77 T 22-04-2016 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 HRM2_RS19555 0c9ca33bdecd4c6282ed2e0458f58210 267 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 32 248 9.2E-40 T 22-04-2016 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 HRM2_RS16880 8ddca20ee4d035202f29864b100ac5fb 75 SUPERFAMILY SSF54862 6 62 1.5E-13 T 22-04-2016 HRM2_RS16880 8ddca20ee4d035202f29864b100ac5fb 75 Pfam PF14697 4Fe-4S dicluster domain 5 60 9.1E-11 T 22-04-2016 HRM2_RS16880 8ddca20ee4d035202f29864b100ac5fb 75 Gene3D G3DSA:3.30.70.20 6 56 6.0E-13 T 22-04-2016 HRM2_RS16880 8ddca20ee4d035202f29864b100ac5fb 75 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 43 54 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS16880 8ddca20ee4d035202f29864b100ac5fb 75 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 11 22 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS22875 cdd7ff89d50a01fcbea5d8c3b1e3e38d 66 PANTHER PTHR40069 1 63 2.6E-22 T 22-04-2016 HRM2_RS22875 cdd7ff89d50a01fcbea5d8c3b1e3e38d 66 PANTHER PTHR40069:SF1 1 63 2.6E-22 T 22-04-2016 HRM2_RS22875 cdd7ff89d50a01fcbea5d8c3b1e3e38d 66 TIGRFAM TIGR03833 TIGR03833: conserved hypothetical protein 3 64 4.9E-32 T 22-04-2016 IPR019240 Protein of unknown function DUF2196 HRM2_RS22875 cdd7ff89d50a01fcbea5d8c3b1e3e38d 66 Pfam PF09962 Uncharacterized conserved protein (DUF2196) 3 62 4.1E-30 T 22-04-2016 IPR019240 Protein of unknown function DUF2196 HRM2_RS12780 8119a4a006307c94e38f30b98182e513 258 SMART SM00363 11 73 6.2E-11 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HRM2_RS12780 8119a4a006307c94e38f30b98182e513 258 Pfam PF01479 S4 domain 12 57 9.8E-11 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HRM2_RS12780 8119a4a006307c94e38f30b98182e513 258 Pfam PF01728 FtsJ-like methyltransferase 67 249 2.4E-20 T 22-04-2016 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 HRM2_RS12780 8119a4a006307c94e38f30b98182e513 258 PANTHER PTHR32319:SF0 5 249 9.1E-122 T 22-04-2016 HRM2_RS12780 8119a4a006307c94e38f30b98182e513 258 PIRSF PIRSF005578 6 257 4.0E-99 T 22-04-2016 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 HRM2_RS12780 8119a4a006307c94e38f30b98182e513 258 SUPERFAMILY SSF55174 9 66 1.77E-12 T 22-04-2016 HRM2_RS12780 8119a4a006307c94e38f30b98182e513 258 Gene3D G3DSA:3.40.50.150 100 185 1.9E-5 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS12780 8119a4a006307c94e38f30b98182e513 258 SUPERFAMILY SSF53335 62 251 1.83E-23 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS12780 8119a4a006307c94e38f30b98182e513 258 Gene3D G3DSA:3.10.290.10 11 99 7.4E-22 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HRM2_RS12780 8119a4a006307c94e38f30b98182e513 258 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 12 243 4.5E-75 T 22-04-2016 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 HRM2_RS12780 8119a4a006307c94e38f30b98182e513 258 PANTHER PTHR32319 5 249 9.1E-122 T 22-04-2016 HRM2_RS25355 21a4210b3880020754be38c8a781caed 1111 Gene3D G3DSA:3.90.550.10 491 738 9.9E-60 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS25355 21a4210b3880020754be38c8a781caed 1111 Gene3D G3DSA:3.40.50.150 27 215 1.0E-28 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS25355 21a4210b3880020754be38c8a781caed 1111 Pfam PF13489 Methyltransferase domain 27 177 2.8E-19 T 22-04-2016 HRM2_RS25355 21a4210b3880020754be38c8a781caed 1111 Pfam PF13692 Glycosyl transferases group 1 938 1073 8.8E-25 T 22-04-2016 HRM2_RS25355 21a4210b3880020754be38c8a781caed 1111 PANTHER PTHR22916 470 749 2.7E-51 T 22-04-2016 HRM2_RS25355 21a4210b3880020754be38c8a781caed 1111 SUPERFAMILY SSF53756 757 1102 1.26E-26 T 22-04-2016 HRM2_RS25355 21a4210b3880020754be38c8a781caed 1111 Pfam PF00535 Glycosyl transferase family 2 492 655 1.8E-23 T 22-04-2016 IPR001173 Glycosyltransferase 2-like HRM2_RS25355 21a4210b3880020754be38c8a781caed 1111 Gene3D G3DSA:3.40.50.150 746 817 5.1E-7 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS25355 21a4210b3880020754be38c8a781caed 1111 SUPERFAMILY SSF53335 24 219 3.22E-30 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS25355 21a4210b3880020754be38c8a781caed 1111 PANTHER PTHR22916:SF26 470 749 2.7E-51 T 22-04-2016 HRM2_RS25355 21a4210b3880020754be38c8a781caed 1111 SUPERFAMILY SSF53448 488 737 5.55E-54 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS22170 7900dd88f4e44819812b8bded31441dd 216 PANTHER PTHR38755:SF1 109 216 2.6E-16 T 22-04-2016 HRM2_RS22170 7900dd88f4e44819812b8bded31441dd 216 Pfam PF12225 Methylene-tetrahydrofolate reductase C terminal 111 205 1.8E-37 T 22-04-2016 IPR022026 Methylene-tetrahydrofolate reductase C-terminal HRM2_RS22170 7900dd88f4e44819812b8bded31441dd 216 PANTHER PTHR38755 109 216 2.6E-16 T 22-04-2016 HRM2_RS03950 d8df113c7267d6b28c8a0b65cd3f00ec 400 Gene3D G3DSA:3.30.390.30 287 396 6.7E-21 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HRM2_RS03950 d8df113c7267d6b28c8a0b65cd3f00ec 400 PANTHER PTHR22912:SF140 5 392 3.6E-88 T 22-04-2016 HRM2_RS03950 d8df113c7267d6b28c8a0b65cd3f00ec 400 SUPERFAMILY SSF55424 278 382 9.79E-18 T 22-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 HRM2_RS03950 d8df113c7267d6b28c8a0b65cd3f00ec 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 186 202 7.4E-14 T 22-04-2016 HRM2_RS03950 d8df113c7267d6b28c8a0b65cd3f00ec 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 50 68 7.4E-14 T 22-04-2016 HRM2_RS03950 d8df113c7267d6b28c8a0b65cd3f00ec 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 97 115 7.4E-14 T 22-04-2016 HRM2_RS03950 d8df113c7267d6b28c8a0b65cd3f00ec 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 212 234 7.4E-14 T 22-04-2016 HRM2_RS03950 d8df113c7267d6b28c8a0b65cd3f00ec 400 Gene3D G3DSA:3.50.50.60 53 194 1.5E-40 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS03950 d8df113c7267d6b28c8a0b65cd3f00ec 400 PANTHER PTHR22912 5 392 3.6E-88 T 22-04-2016 HRM2_RS03950 d8df113c7267d6b28c8a0b65cd3f00ec 400 Gene3D G3DSA:3.50.50.60 16 52 3.4E-20 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS03950 d8df113c7267d6b28c8a0b65cd3f00ec 400 Gene3D G3DSA:3.50.50.60 195 269 3.4E-20 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS03950 d8df113c7267d6b28c8a0b65cd3f00ec 400 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 283 381 8.5E-11 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HRM2_RS03950 d8df113c7267d6b28c8a0b65cd3f00ec 400 SUPERFAMILY SSF51905 147 296 3.15E-36 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS03950 d8df113c7267d6b28c8a0b65cd3f00ec 400 SUPERFAMILY SSF51905 28 114 3.15E-36 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS03950 d8df113c7267d6b28c8a0b65cd3f00ec 400 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 20 237 2.5E-46 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS01550 d167a8f2ce057e0666e645b86e2ece80 430 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 18 422 1.8E-114 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS01550 d167a8f2ce057e0666e645b86e2ece80 430 PANTHER PTHR33362:SF2 5 426 9.8E-117 T 22-04-2016 HRM2_RS01550 d167a8f2ce057e0666e645b86e2ece80 430 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 8 416 2.3E-105 T 22-04-2016 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit HRM2_RS01550 d167a8f2ce057e0666e645b86e2ece80 430 PIRSF PIRSF006066 2 428 1.0E-133 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS01550 d167a8f2ce057e0666e645b86e2ece80 430 PANTHER PTHR33362 5 426 9.8E-117 T 22-04-2016 HRM2_RS20770 453cdfe43fc7f6a1fe5a131d821031f4 446 PANTHER PTHR22912:SF140 1 440 2.5E-110 T 22-04-2016 HRM2_RS20770 453cdfe43fc7f6a1fe5a131d821031f4 446 Gene3D G3DSA:3.50.50.60 114 315 3.1E-46 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS20770 453cdfe43fc7f6a1fe5a131d821031f4 446 SUPERFAMILY SSF55424 322 445 5.67E-29 T 22-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 HRM2_RS20770 453cdfe43fc7f6a1fe5a131d821031f4 446 SUPERFAMILY SSF51905 2 315 1.08E-40 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS20770 453cdfe43fc7f6a1fe5a131d821031f4 446 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 306 1.0E-51 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS20770 453cdfe43fc7f6a1fe5a131d821031f4 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 276 283 2.2E-15 T 22-04-2016 HRM2_RS20770 453cdfe43fc7f6a1fe5a131d821031f4 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 2.2E-15 T 22-04-2016 HRM2_RS20770 453cdfe43fc7f6a1fe5a131d821031f4 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 2.2E-15 T 22-04-2016 HRM2_RS20770 453cdfe43fc7f6a1fe5a131d821031f4 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 151 176 2.2E-15 T 22-04-2016 HRM2_RS20770 453cdfe43fc7f6a1fe5a131d821031f4 446 PANTHER PTHR22912 1 440 2.5E-110 T 22-04-2016 HRM2_RS20770 453cdfe43fc7f6a1fe5a131d821031f4 446 Gene3D G3DSA:3.50.50.60 1 113 6.4E-19 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS20770 453cdfe43fc7f6a1fe5a131d821031f4 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 2.2E-23 T 22-04-2016 HRM2_RS20770 453cdfe43fc7f6a1fe5a131d821031f4 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 151 169 2.2E-23 T 22-04-2016 HRM2_RS20770 453cdfe43fc7f6a1fe5a131d821031f4 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 2.2E-23 T 22-04-2016 HRM2_RS20770 453cdfe43fc7f6a1fe5a131d821031f4 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 2.2E-23 T 22-04-2016 HRM2_RS20770 453cdfe43fc7f6a1fe5a131d821031f4 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 2.2E-23 T 22-04-2016 HRM2_RS20770 453cdfe43fc7f6a1fe5a131d821031f4 446 Gene3D G3DSA:3.30.390.30 334 445 5.7E-31 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HRM2_RS20770 453cdfe43fc7f6a1fe5a131d821031f4 446 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 329 429 9.6E-15 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HRM2_RS16805 aff55a6ae25acc78c703f75f4d024dc1 444 PANTHER PTHR30026:SF4 26 440 1.1E-43 T 22-04-2016 HRM2_RS16805 aff55a6ae25acc78c703f75f4d024dc1 444 SUPERFAMILY SSF56954 4 440 6.28E-75 T 22-04-2016 HRM2_RS16805 aff55a6ae25acc78c703f75f4d024dc1 444 Gene3D G3DSA:1.20.1600.10 29 440 1.7E-65 T 22-04-2016 HRM2_RS16805 aff55a6ae25acc78c703f75f4d024dc1 444 Pfam PF02321 Outer membrane efflux protein 34 226 3.5E-30 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS16805 aff55a6ae25acc78c703f75f4d024dc1 444 Pfam PF02321 Outer membrane efflux protein 254 438 9.2E-22 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS16805 aff55a6ae25acc78c703f75f4d024dc1 444 PANTHER PTHR30026 26 440 1.1E-43 T 22-04-2016 HRM2_RS22125 016ca029862e6e772d5961d030ba4a22 255 PANTHER PTHR21235 1 247 1.9E-123 T 22-04-2016 HRM2_RS22125 016ca029862e6e772d5961d030ba4a22 255 PANTHER PTHR21235:SF23 1 247 1.9E-123 T 22-04-2016 HRM2_RS22125 016ca029862e6e772d5961d030ba4a22 255 Gene3D G3DSA:3.20.20.70 1 248 2.2E-45 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS22125 016ca029862e6e772d5961d030ba4a22 255 TIGRFAM TIGR02129 hisA_euk: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase 2 248 7.6E-105 T 22-04-2016 IPR011858 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase, eukaryotic GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16|UniPathway: UPA00031 HRM2_RS22125 016ca029862e6e772d5961d030ba4a22 255 Pfam PF00977 Histidine biosynthesis protein 5 234 1.8E-28 T 22-04-2016 IPR006062 Histidine biosynthesis GO:0000105 HRM2_RS22125 016ca029862e6e772d5961d030ba4a22 255 SUPERFAMILY SSF51366 1 248 4.4E-42 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 HRM2_RS23565 769f3ad3c599963bda851e9f68ccd380 684 PANTHER PTHR32071 349 684 5.0E-140 T 22-04-2016 HRM2_RS23565 769f3ad3c599963bda851e9f68ccd380 684 SUPERFAMILY SSF55785 253 345 1.74E-8 T 22-04-2016 IPR000014 PAS domain HRM2_RS23565 769f3ad3c599963bda851e9f68ccd380 684 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 401 414 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS23565 769f3ad3c599963bda851e9f68ccd380 684 Gene3D G3DSA:3.30.450.20 240 320 2.2E-8 T 22-04-2016 HRM2_RS23565 769f3ad3c599963bda851e9f68ccd380 684 Gene3D G3DSA:3.40.50.300 374 550 1.2E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23565 769f3ad3c599963bda851e9f68ccd380 684 Gene3D G3DSA:1.10.10.60 633 683 7.0E-15 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS23565 769f3ad3c599963bda851e9f68ccd380 684 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 591 600 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS23565 769f3ad3c599963bda851e9f68ccd380 684 SUPERFAMILY SSF46689 591 683 2.28E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS23565 769f3ad3c599963bda851e9f68ccd380 684 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 464 479 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS23565 769f3ad3c599963bda851e9f68ccd380 684 Pfam PF00158 Sigma-54 interaction domain 378 544 4.8E-68 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS23565 769f3ad3c599963bda851e9f68ccd380 684 Gene3D G3DSA:1.10.8.60 551 619 3.7E-18 T 22-04-2016 HRM2_RS23565 769f3ad3c599963bda851e9f68ccd380 684 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 647 664 1.84E-5 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS23565 769f3ad3c599963bda851e9f68ccd380 684 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 664 684 1.84E-5 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS23565 769f3ad3c599963bda851e9f68ccd380 684 Pfam PF02954 Bacterial regulatory protein, Fis family 643 681 5.5E-10 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS23565 769f3ad3c599963bda851e9f68ccd380 684 SUPERFAMILY SSF52540 377 615 1.83E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23565 769f3ad3c599963bda851e9f68ccd380 684 SMART SM00382 397 541 6.8E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS05280 fb0e4abc542448a5d68a0f437fe56677 178 PANTHER PTHR32154:SF15 1 175 7.0E-50 T 22-04-2016 HRM2_RS05280 fb0e4abc542448a5d68a0f437fe56677 178 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 173 2.6E-35 T 22-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HRM2_RS05280 fb0e4abc542448a5d68a0f437fe56677 178 Gene3D G3DSA:3.40.920.10 1 175 3.2E-47 T 22-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HRM2_RS05280 fb0e4abc542448a5d68a0f437fe56677 178 PANTHER PTHR32154 1 175 7.0E-50 T 22-04-2016 HRM2_RS05280 fb0e4abc542448a5d68a0f437fe56677 178 SUPERFAMILY SSF53323 2 176 2.62E-41 T 22-04-2016 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 HRM2_RS17495 85963174cf6011c6dc79df8b45039e4d 166 PANTHER PTHR34584:SF2 10 164 9.8E-29 T 22-04-2016 HRM2_RS17495 85963174cf6011c6dc79df8b45039e4d 166 Pfam PF01899 Na+/H+ ion antiporter subunit 14 161 3.0E-36 T 22-04-2016 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 HRM2_RS17495 85963174cf6011c6dc79df8b45039e4d 166 PIRSF PIRSF019239 4 165 5.6E-34 T 22-04-2016 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 HRM2_RS17495 85963174cf6011c6dc79df8b45039e4d 166 PANTHER PTHR34584 10 164 9.8E-29 T 22-04-2016 HRM2_RS21095 b6f8ed0cb42b062cda18576f4d9c5f9a 425 SUPERFAMILY SSF51695 75 417 1.67E-66 T 22-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 HRM2_RS21095 b6f8ed0cb42b062cda18576f4d9c5f9a 425 Gene3D G3DSA:3.20.20.190 75 416 1.2E-60 T 22-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 HRM2_RS21095 b6f8ed0cb42b062cda18576f4d9c5f9a 425 PANTHER PTHR23344:SF7 73 363 8.4E-73 T 22-04-2016 HRM2_RS21095 b6f8ed0cb42b062cda18576f4d9c5f9a 425 PANTHER PTHR23344:SF7 381 425 8.4E-73 T 22-04-2016 HRM2_RS21095 b6f8ed0cb42b062cda18576f4d9c5f9a 425 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 77 413 4.4E-19 T 22-04-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 HRM2_RS21095 b6f8ed0cb42b062cda18576f4d9c5f9a 425 PANTHER PTHR23344 73 363 8.4E-73 T 22-04-2016 IPR004129 Glycerophosphoryl diester phosphodiesterase GO:0008889 HRM2_RS21095 b6f8ed0cb42b062cda18576f4d9c5f9a 425 PANTHER PTHR23344 381 425 8.4E-73 T 22-04-2016 IPR004129 Glycerophosphoryl diester phosphodiesterase GO:0008889 HRM2_RS06815 594ab691514bcd70718ff319963b5ccd 708 SMART SM00086 412 454 2.2E-5 T 22-04-2016 IPR001610 PAC motif HRM2_RS06815 594ab691514bcd70718ff319963b5ccd 708 SMART SM00387 611 705 1.8E-8 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS06815 594ab691514bcd70718ff319963b5ccd 708 Pfam PF07730 Histidine kinase 507 574 2.5E-13 T 22-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 HRM2_RS06815 594ab691514bcd70718ff319963b5ccd 708 SUPERFAMILY SSF55785 324 452 6.77E-21 T 22-04-2016 IPR000014 PAS domain HRM2_RS06815 594ab691514bcd70718ff319963b5ccd 708 PANTHER PTHR24421:SF1 466 697 1.2E-41 T 22-04-2016 HRM2_RS06815 594ab691514bcd70718ff319963b5ccd 708 PANTHER PTHR24421 466 697 1.2E-41 T 22-04-2016 HRM2_RS06815 594ab691514bcd70718ff319963b5ccd 708 Pfam PF13426 PAS domain 355 453 6.5E-14 T 22-04-2016 IPR000014 PAS domain HRM2_RS06815 594ab691514bcd70718ff319963b5ccd 708 SUPERFAMILY SSF103190 92 175 1.33E-16 T 22-04-2016 IPR029151 Periplasmic sensor domain-like HRM2_RS06815 594ab691514bcd70718ff319963b5ccd 708 Gene3D G3DSA:3.30.565.10 579 700 5.6E-11 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS06815 594ab691514bcd70718ff319963b5ccd 708 SUPERFAMILY SSF55874 575 699 1.03E-18 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS06815 594ab691514bcd70718ff319963b5ccd 708 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 614 701 2.5E-7 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS06815 594ab691514bcd70718ff319963b5ccd 708 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 337 461 8.9E-15 T 22-04-2016 IPR000014 PAS domain HRM2_RS06815 594ab691514bcd70718ff319963b5ccd 708 Gene3D G3DSA:3.30.450.20 324 452 3.3E-20 T 22-04-2016 HRM2_RS06815 594ab691514bcd70718ff319963b5ccd 708 Gene3D G3DSA:3.30.450.20 92 177 4.0E-6 T 22-04-2016 HRM2_RS06815 594ab691514bcd70718ff319963b5ccd 708 SMART SM00091 339 405 3.0E-4 T 22-04-2016 IPR000014 PAS domain HRM2_RS04775 4b30167c4c1b734077da8e7619e48bfc 532 Gene3D G3DSA:3.40.50.1980 3 165 4.1E-58 T 22-04-2016 HRM2_RS04775 4b30167c4c1b734077da8e7619e48bfc 532 Gene3D G3DSA:3.40.50.1980 194 306 1.0E-39 T 22-04-2016 HRM2_RS04775 4b30167c4c1b734077da8e7619e48bfc 532 TIGRFAM TIGR01862 N2-ase-Ialpha: nitrogenase component I, alpha chain 18 512 2.6E-163 T 22-04-2016 IPR010143 Nitrogenase component 1, alpha chain GO:0009399|GO:0016163|GO:0051536|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 HRM2_RS04775 4b30167c4c1b734077da8e7619e48bfc 532 ProSitePatterns PS00090 Nitrogenases component 1 alpha and beta subunits signature 2. 142 156 - T 22-04-2016 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 HRM2_RS04775 4b30167c4c1b734077da8e7619e48bfc 532 SUPERFAMILY SSF53807 5 521 2.8E-155 T 22-04-2016 HRM2_RS04775 4b30167c4c1b734077da8e7619e48bfc 532 PANTHER PTHR33712 430 520 2.9E-179 T 22-04-2016 HRM2_RS04775 4b30167c4c1b734077da8e7619e48bfc 532 PANTHER PTHR33712 10 379 2.9E-179 T 22-04-2016 HRM2_RS04775 4b30167c4c1b734077da8e7619e48bfc 532 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 52 507 2.2E-125 T 22-04-2016 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 HRM2_RS04775 4b30167c4c1b734077da8e7619e48bfc 532 PANTHER PTHR33712:SF4 430 520 2.9E-179 T 22-04-2016 HRM2_RS04775 4b30167c4c1b734077da8e7619e48bfc 532 PANTHER PTHR33712:SF4 10 379 2.9E-179 T 22-04-2016 HRM2_RS04775 4b30167c4c1b734077da8e7619e48bfc 532 Gene3D G3DSA:3.40.50.1980 333 376 1.2E-56 T 22-04-2016 HRM2_RS04775 4b30167c4c1b734077da8e7619e48bfc 532 Gene3D G3DSA:3.40.50.1980 429 529 1.2E-56 T 22-04-2016 HRM2_RS04775 4b30167c4c1b734077da8e7619e48bfc 532 ProSitePatterns PS00699 Nitrogenases component 1 alpha and beta subunits signature 1. 71 78 - T 22-04-2016 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 HRM2_RS07390 6f2f7532bcae8db7c4bd50365f18f599 385 Gene3D G3DSA:3.30.470.20 106 366 4.7E-27 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS07390 6f2f7532bcae8db7c4bd50365f18f599 385 SUPERFAMILY SSF56059 93 323 6.89E-37 T 22-04-2016 HRM2_RS07390 6f2f7532bcae8db7c4bd50365f18f599 385 Pfam PF02655 ATP-grasp domain 143 281 1.3E-6 T 22-04-2016 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 HRM2_RS13790 85c177c5e2466e9497972b8de881c08b 240 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 4 240 1.8E-106 T 22-04-2016 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 HRM2_RS13790 85c177c5e2466e9497972b8de881c08b 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS13790 85c177c5e2466e9497972b8de881c08b 240 PANTHER PTHR24220 5 236 7.3E-127 T 22-04-2016 HRM2_RS13790 85c177c5e2466e9497972b8de881c08b 240 Gene3D G3DSA:3.40.50.300 3 229 5.8E-65 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13790 85c177c5e2466e9497972b8de881c08b 240 SUPERFAMILY SSF52540 4 231 2.41E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13790 85c177c5e2466e9497972b8de881c08b 240 PANTHER PTHR24220:SF497 5 236 7.3E-127 T 22-04-2016 HRM2_RS13790 85c177c5e2466e9497972b8de881c08b 240 SMART SM00382 28 238 7.2E-6 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS13790 85c177c5e2466e9497972b8de881c08b 240 Pfam PF00005 ABC transporter 20 165 1.8E-32 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS25335 b7949d12ced3f8d9c27d933b47aa4ccc 965 Gene3D G3DSA:3.40.50.2300 3 134 1.3E-30 T 22-04-2016 HRM2_RS25335 b7949d12ced3f8d9c27d933b47aa4ccc 965 PANTHER PTHR38032 283 813 1.5E-42 T 22-04-2016 HRM2_RS25335 b7949d12ced3f8d9c27d933b47aa4ccc 965 SUPERFAMILY SSF52172 6 156 1.99E-31 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS25335 b7949d12ced3f8d9c27d933b47aa4ccc 965 Pfam PF03961 Protein of unknown function (DUF342) 452 869 2.6E-75 T 22-04-2016 IPR005646 Protein of unknown function DUF342 HRM2_RS25335 b7949d12ced3f8d9c27d933b47aa4ccc 965 Pfam PF00072 Response regulator receiver domain 9 122 8.3E-22 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS25335 b7949d12ced3f8d9c27d933b47aa4ccc 965 SMART SM00448 7 122 2.1E-24 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS22510 6398f38c06e98bf29ff864386a550918 544 Pfam PF12848 ABC transporter 230 313 6.3E-26 T 22-04-2016 IPR032781 ABC-transporter extension domain HRM2_RS22510 6398f38c06e98bf29ff864386a550918 544 SUPERFAMILY SSF52540 2 241 1.19E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22510 6398f38c06e98bf29ff864386a550918 544 Gene3D G3DSA:3.40.50.300 1 88 5.0E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22510 6398f38c06e98bf29ff864386a550918 544 Gene3D G3DSA:3.40.50.300 123 278 5.0E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22510 6398f38c06e98bf29ff864386a550918 544 PANTHER PTHR19211:SF51 1 540 0.0 T 22-04-2016 HRM2_RS22510 6398f38c06e98bf29ff864386a550918 544 Pfam PF00005 ABC transporter 18 190 1.5E-22 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS22510 6398f38c06e98bf29ff864386a550918 544 Pfam PF00005 ABC transporter 347 477 2.7E-18 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS22510 6398f38c06e98bf29ff864386a550918 544 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS22510 6398f38c06e98bf29ff864386a550918 544 ProSitePatterns PS00211 ABC transporters family signature. 449 463 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS22510 6398f38c06e98bf29ff864386a550918 544 SUPERFAMILY SSF52540 303 534 1.55E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22510 6398f38c06e98bf29ff864386a550918 544 SMART SM00382 355 522 3.5E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS22510 6398f38c06e98bf29ff864386a550918 544 SMART SM00382 26 236 3.3E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS22510 6398f38c06e98bf29ff864386a550918 544 PANTHER PTHR19211 1 540 0.0 T 22-04-2016 HRM2_RS22510 6398f38c06e98bf29ff864386a550918 544 Gene3D G3DSA:3.40.50.300 328 539 8.6E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05050 03ff3a80cc60d062c35b21cc3c5e377a 286 SUPERFAMILY SSF52402 160 271 2.37E-5 T 22-04-2016 HRM2_RS05050 03ff3a80cc60d062c35b21cc3c5e377a 286 SUPERFAMILY SSF52402 4 154 2.37E-7 T 22-04-2016 HRM2_RS05050 03ff3a80cc60d062c35b21cc3c5e377a 286 Gene3D G3DSA:3.40.50.620 1 154 2.7E-8 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS05050 03ff3a80cc60d062c35b21cc3c5e377a 286 Pfam PF00582 Universal stress protein family 1 152 1.6E-5 T 22-04-2016 IPR006016 UspA GO:0006950 HRM2_RS02480 8aded5b9f3c274122201dbf14870cfc9 207 Gene3D G3DSA:3.40.50.2300 82 188 1.5E-5 T 22-04-2016 HRM2_RS02480 8aded5b9f3c274122201dbf14870cfc9 207 SUPERFAMILY SSF52172 83 189 2.33E-6 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS02480 8aded5b9f3c274122201dbf14870cfc9 207 Pfam PF13717 zinc-ribbon domain 2 37 5.3E-8 T 22-04-2016 HRM2_RS16845 1f3f1d201b461aec22dc8ce091b019e8 221 Pfam PF00857 Isochorismatase family 28 214 1.6E-35 T 22-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 HRM2_RS16845 1f3f1d201b461aec22dc8ce091b019e8 221 PANTHER PTHR11080:SF19 3 217 3.0E-42 T 22-04-2016 HRM2_RS16845 1f3f1d201b461aec22dc8ce091b019e8 221 PANTHER PTHR11080 3 217 3.0E-42 T 22-04-2016 HRM2_RS16845 1f3f1d201b461aec22dc8ce091b019e8 221 SUPERFAMILY SSF52499 8 221 8.63E-49 T 22-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 HRM2_RS16845 1f3f1d201b461aec22dc8ce091b019e8 221 Gene3D G3DSA:3.40.50.850 8 218 3.7E-54 T 22-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 HRM2_RS23405 8343e553882175c0898acf78a83e1c56 373 Gene3D G3DSA:3.40.50.1980 179 343 2.2E-26 T 22-04-2016 HRM2_RS23405 8343e553882175c0898acf78a83e1c56 373 SUPERFAMILY SSF53807 33 333 1.3E-40 T 22-04-2016 HRM2_RS23405 8343e553882175c0898acf78a83e1c56 373 PANTHER PTHR30535 14 364 2.1E-100 T 22-04-2016 HRM2_RS23405 8343e553882175c0898acf78a83e1c56 373 PANTHER PTHR30535:SF16 14 364 2.1E-100 T 22-04-2016 HRM2_RS23405 8343e553882175c0898acf78a83e1c56 373 Pfam PF01497 Periplasmic binding protein 51 304 1.6E-20 T 22-04-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 HRM2_RS23405 8343e553882175c0898acf78a83e1c56 373 Gene3D G3DSA:3.40.50.1980 50 178 1.0E-8 T 22-04-2016 HRM2_RS14230 96c35cf344943cacc67e2c7fa26315fc 438 Gene3D G3DSA:1.25.40.10 290 417 2.0E-20 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS14230 96c35cf344943cacc67e2c7fa26315fc 438 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 7 29 4.1E-6 T 22-04-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal HRM2_RS14230 96c35cf344943cacc67e2c7fa26315fc 438 PANTHER PTHR22726 13 349 2.8E-62 T 22-04-2016 HRM2_RS14230 96c35cf344943cacc67e2c7fa26315fc 438 Pfam PF13432 Tetratricopeptide repeat 292 355 3.7E-6 T 22-04-2016 HRM2_RS14230 96c35cf344943cacc67e2c7fa26315fc 438 PANTHER PTHR22726:SF9 13 349 2.8E-62 T 22-04-2016 HRM2_RS14230 96c35cf344943cacc67e2c7fa26315fc 438 Pfam PF01435 Peptidase family M48 74 250 3.8E-31 T 22-04-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 HRM2_RS14230 96c35cf344943cacc67e2c7fa26315fc 438 SUPERFAMILY SSF48452 289 417 4.11E-21 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS14230 96c35cf344943cacc67e2c7fa26315fc 438 Gene3D G3DSA:3.30.2010.10 71 148 2.0E-15 T 22-04-2016 HRM2_RS15555 9ba18428ef51cccaa7813ebea1c9bf09 638 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 310 1.9E-87 T 22-04-2016 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 HRM2_RS15555 9ba18428ef51cccaa7813ebea1c9bf09 638 SUPERFAMILY SSF54211 190 330 3.03E-29 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS15555 9ba18428ef51cccaa7813ebea1c9bf09 638 PANTHER PTHR10073 4 621 2.7E-150 T 22-04-2016 HRM2_RS15555 9ba18428ef51cccaa7813ebea1c9bf09 638 SUPERFAMILY SSF118116 449 636 2.09E-50 T 22-04-2016 HRM2_RS15555 9ba18428ef51cccaa7813ebea1c9bf09 638 SMART SM01340 209 330 1.1E-45 T 22-04-2016 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 HRM2_RS15555 9ba18428ef51cccaa7813ebea1c9bf09 638 Gene3D G3DSA:3.30.230.10 203 329 3.1E-29 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HRM2_RS15555 9ba18428ef51cccaa7813ebea1c9bf09 638 Pfam PF08676 MutL C terminal dimerisation domain 450 594 1.8E-38 T 22-04-2016 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 HRM2_RS15555 9ba18428ef51cccaa7813ebea1c9bf09 638 SUPERFAMILY SSF55874 2 212 9.3E-50 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS15555 9ba18428ef51cccaa7813ebea1c9bf09 638 Gene3D G3DSA:3.30.565.10 4 202 1.5E-66 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS15555 9ba18428ef51cccaa7813ebea1c9bf09 638 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 94 100 - T 22-04-2016 IPR014762 DNA mismatch repair, conserved site HRM2_RS15555 9ba18428ef51cccaa7813ebea1c9bf09 638 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 26 126 3.9E-8 T 22-04-2016 HRM2_RS15555 9ba18428ef51cccaa7813ebea1c9bf09 638 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 634 25.134 T 22-04-2016 IPR020667 DNA mismatch repair protein, MutL GO:0006298 HRM2_RS15555 9ba18428ef51cccaa7813ebea1c9bf09 638 SMART SM00853 449 594 1.1E-46 T 22-04-2016 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 HRM2_RS15555 9ba18428ef51cccaa7813ebea1c9bf09 638 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 211 329 8.9E-30 T 22-04-2016 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 HRM2_RS11705 0b70ccad16a1e4552727429abac043e7 229 Pfam PF00899 ThiF family 4 228 3.9E-49 T 22-04-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 HRM2_RS11705 0b70ccad16a1e4552727429abac043e7 229 SUPERFAMILY SSF69572 1 228 1.44E-64 T 22-04-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 HRM2_RS11705 0b70ccad16a1e4552727429abac043e7 229 PANTHER PTHR10953 2 228 2.2E-43 T 22-04-2016 HRM2_RS11705 0b70ccad16a1e4552727429abac043e7 229 Gene3D G3DSA:3.40.50.720 2 228 2.5E-59 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS08875 ece2b88facb79eaa35fdefa4f56b58d7 89 Gene3D G3DSA:1.20.20.10 8 74 3.3E-23 T 22-04-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 HRM2_RS08875 ece2b88facb79eaa35fdefa4f56b58d7 89 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 18 75 4.3E-15 T 22-04-2016 IPR005953 ATPase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 HRM2_RS08875 ece2b88facb79eaa35fdefa4f56b58d7 89 Pfam PF00137 ATP synthase subunit C 10 72 1.7E-15 T 22-04-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 HRM2_RS08875 ece2b88facb79eaa35fdefa4f56b58d7 89 PANTHER PTHR10031 10 76 6.3E-18 T 22-04-2016 HRM2_RS08875 ece2b88facb79eaa35fdefa4f56b58d7 89 ProSitePatterns PS00605 ATP synthase c subunit signature. 38 59 - T 22-04-2016 IPR020537 ATPase, F0 complex, subunit C, DCCD-binding site HRM2_RS08875 ece2b88facb79eaa35fdefa4f56b58d7 89 SUPERFAMILY SSF81333 6 76 4.45E-19 T 22-04-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 HRM2_RS08875 ece2b88facb79eaa35fdefa4f56b58d7 89 PRINTS PR00124 ATP synthase C subunit signature 48 73 2.7E-18 T 22-04-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 HRM2_RS08875 ece2b88facb79eaa35fdefa4f56b58d7 89 PRINTS PR00124 ATP synthase C subunit signature 31 46 2.7E-18 T 22-04-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 HRM2_RS08875 ece2b88facb79eaa35fdefa4f56b58d7 89 PRINTS PR00124 ATP synthase C subunit signature 10 29 2.7E-18 T 22-04-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 HRM2_RS08875 ece2b88facb79eaa35fdefa4f56b58d7 89 Hamap MF_01396 ATP synthase subunit c [atpH]. 7 75 16.998 T 22-04-2016 HRM2_RS17480 32941d95368dd3d43545173e6a648a1e 81 PANTHER PTHR33932 1 77 6.7E-15 T 22-04-2016 HRM2_RS17480 32941d95368dd3d43545173e6a648a1e 81 PANTHER PTHR33932:SF1 1 77 6.7E-15 T 22-04-2016 HRM2_RS17480 32941d95368dd3d43545173e6a648a1e 81 Pfam PF13244 Domain of unknown function (DUF4040) 11 76 8.5E-19 T 22-04-2016 IPR025383 Domain of unknown function DUF4040 HRM2_RS23165 bc1d599b7f8f6a1405f4d4898311f4e3 190 PANTHER PTHR33937:SF2 1 129 3.8E-28 T 22-04-2016 HRM2_RS23165 bc1d599b7f8f6a1405f4d4898311f4e3 190 PANTHER PTHR33937 1 129 3.8E-28 T 22-04-2016 HRM2_RS23165 bc1d599b7f8f6a1405f4d4898311f4e3 190 Gene3D G3DSA:3.30.420.130 1 109 2.2E-31 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS23165 bc1d599b7f8f6a1405f4d4898311f4e3 190 SUPERFAMILY SSF53146 1 110 3.92E-27 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS23165 bc1d599b7f8f6a1405f4d4898311f4e3 190 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 14 102 2.7E-22 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS10810 36aa7e4f94b6ce63149d1dc3d3bf1e09 551 Pfam PF11067 Protein of unknown function (DUF2868) 172 540 4.4E-86 T 22-04-2016 IPR021296 Protein of unknown function DUF2868 HRM2_RS20600 49e7d440e7d5d910c93d63386cb5a4db 287 Pfam PF12800 4Fe-4S binding domain 182 194 0.43 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS20600 49e7d440e7d5d910c93d63386cb5a4db 287 Gene3D G3DSA:3.30.70.20 153 251 1.6E-5 T 22-04-2016 HRM2_RS20600 49e7d440e7d5d910c93d63386cb5a4db 287 SUPERFAMILY SSF46548 30 111 7.15E-11 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS20600 49e7d440e7d5d910c93d63386cb5a4db 287 Gene3D G3DSA:1.10.1060.10 30 108 1.4E-9 T 22-04-2016 HRM2_RS20600 49e7d440e7d5d910c93d63386cb5a4db 287 SUPERFAMILY SSF46548 176 237 1.57E-8 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS20600 49e7d440e7d5d910c93d63386cb5a4db 287 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 32 43 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS20600 49e7d440e7d5d910c93d63386cb5a4db 287 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 77 88 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS20600 49e7d440e7d5d910c93d63386cb5a4db 287 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 183 194 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS20600 49e7d440e7d5d910c93d63386cb5a4db 287 Pfam PF13534 4Fe-4S dicluster domain 31 91 7.9E-6 T 22-04-2016 HRM2_RS25005 eb71a1dd73ebbfb94efefa8b77dd02f2 671 Gene3D G3DSA:3.40.250.10 51 193 5.4E-31 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS25005 eb71a1dd73ebbfb94efefa8b77dd02f2 671 PANTHER PTHR11364:SF15 315 389 2.8E-58 T 22-04-2016 HRM2_RS25005 eb71a1dd73ebbfb94efefa8b77dd02f2 671 PANTHER PTHR11364:SF15 427 647 2.8E-58 T 22-04-2016 HRM2_RS25005 eb71a1dd73ebbfb94efefa8b77dd02f2 671 PANTHER PTHR11364 315 389 2.8E-58 T 22-04-2016 HRM2_RS25005 eb71a1dd73ebbfb94efefa8b77dd02f2 671 PANTHER PTHR11364 427 647 2.8E-58 T 22-04-2016 HRM2_RS25005 eb71a1dd73ebbfb94efefa8b77dd02f2 671 Gene3D G3DSA:3.40.250.10 204 317 1.3E-26 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS25005 eb71a1dd73ebbfb94efefa8b77dd02f2 671 SMART SM00450 55 178 4.1E-17 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS25005 eb71a1dd73ebbfb94efefa8b77dd02f2 671 SMART SM00450 201 320 8.6E-16 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS25005 eb71a1dd73ebbfb94efefa8b77dd02f2 671 SMART SM00450 514 651 8.7E-13 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS25005 eb71a1dd73ebbfb94efefa8b77dd02f2 671 SMART SM00450 334 489 7.8E-12 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS25005 eb71a1dd73ebbfb94efefa8b77dd02f2 671 SUPERFAMILY SSF52821 525 651 6.02E-27 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS25005 eb71a1dd73ebbfb94efefa8b77dd02f2 671 SUPERFAMILY SSF52821 333 381 9.48E-22 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS25005 eb71a1dd73ebbfb94efefa8b77dd02f2 671 SUPERFAMILY SSF52821 438 558 9.48E-22 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS25005 eb71a1dd73ebbfb94efefa8b77dd02f2 671 SUPERFAMILY SSF52821 202 318 1.14E-29 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS25005 eb71a1dd73ebbfb94efefa8b77dd02f2 671 Gene3D G3DSA:3.40.250.10 423 497 1.9E-30 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS25005 eb71a1dd73ebbfb94efefa8b77dd02f2 671 Gene3D G3DSA:3.40.250.10 327 386 1.9E-30 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS25005 eb71a1dd73ebbfb94efefa8b77dd02f2 671 Pfam PF00581 Rhodanese-like domain 535 646 1.5E-12 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS25005 eb71a1dd73ebbfb94efefa8b77dd02f2 671 Pfam PF00581 Rhodanese-like domain 419 485 5.3E-6 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS25005 eb71a1dd73ebbfb94efefa8b77dd02f2 671 Pfam PF00581 Rhodanese-like domain 72 174 1.0E-15 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS25005 eb71a1dd73ebbfb94efefa8b77dd02f2 671 Pfam PF00581 Rhodanese-like domain 208 316 5.6E-12 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS25005 eb71a1dd73ebbfb94efefa8b77dd02f2 671 SUPERFAMILY SSF52821 55 196 1.31E-28 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS25005 eb71a1dd73ebbfb94efefa8b77dd02f2 671 ProSitePatterns PS00380 Rhodanese signature 1. 363 374 - T 22-04-2016 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 HRM2_RS25005 eb71a1dd73ebbfb94efefa8b77dd02f2 671 Gene3D G3DSA:3.40.250.10 530 647 7.5E-24 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS16290 3bc33de87643596add288458a2c0f9c8 383 SUPERFAMILY SSF102114 103 287 6.93E-23 T 22-04-2016 HRM2_RS16290 3bc33de87643596add288458a2c0f9c8 383 Pfam PF04055 Radical SAM superfamily 27 222 4.4E-10 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS16290 3bc33de87643596add288458a2c0f9c8 383 SMART SM00729 21 280 2.2E-20 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS16290 3bc33de87643596add288458a2c0f9c8 383 PANTHER PTHR11918 14 84 1.3E-36 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein HRM2_RS16290 3bc33de87643596add288458a2c0f9c8 383 PANTHER PTHR11918 117 260 1.3E-36 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein HRM2_RS16290 3bc33de87643596add288458a2c0f9c8 383 PANTHER PTHR11918:SF47 14 84 1.3E-36 T 22-04-2016 HRM2_RS16290 3bc33de87643596add288458a2c0f9c8 383 PANTHER PTHR11918:SF47 117 260 1.3E-36 T 22-04-2016 HRM2_RS16290 3bc33de87643596add288458a2c0f9c8 383 Gene3D G3DSA:3.80.30.20 108 261 8.1E-20 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe HRM2_RS16290 3bc33de87643596add288458a2c0f9c8 383 Gene3D G3DSA:3.80.30.20 23 64 8.1E-20 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe HRM2_RS13490 2ac3d54efb5759ba2e286a3eb18f0017 344 PANTHER PTHR30081 1 160 5.3E-59 T 22-04-2016 HRM2_RS13490 2ac3d54efb5759ba2e286a3eb18f0017 344 PANTHER PTHR30081 207 340 5.3E-59 T 22-04-2016 HRM2_RS13490 2ac3d54efb5759ba2e286a3eb18f0017 344 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 185 333 1.5E-54 T 22-04-2016 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 HRM2_RS13490 2ac3d54efb5759ba2e286a3eb18f0017 344 Pfam PF07549 SecD/SecF GG Motif 34 57 3.0E-8 T 22-04-2016 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site HRM2_RS13490 2ac3d54efb5759ba2e286a3eb18f0017 344 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 10 344 29.787 T 22-04-2016 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 HRM2_RS13490 2ac3d54efb5759ba2e286a3eb18f0017 344 Gene3D G3DSA:1.20.1640.10 189 343 1.5E-25 T 22-04-2016 HRM2_RS13490 2ac3d54efb5759ba2e286a3eb18f0017 344 Pfam PF02355 Protein export membrane protein 114 186 8.1E-11 T 22-04-2016 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial HRM2_RS13490 2ac3d54efb5759ba2e286a3eb18f0017 344 Pfam PF02355 Protein export membrane protein 187 342 7.7E-56 T 22-04-2016 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial HRM2_RS13490 2ac3d54efb5759ba2e286a3eb18f0017 344 SUPERFAMILY SSF82866 187 343 1.7E-35 T 22-04-2016 HRM2_RS13490 2ac3d54efb5759ba2e286a3eb18f0017 344 PRINTS PR01755 Bacterial translocase SecF protein signature 201 215 1.4E-24 T 22-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial HRM2_RS13490 2ac3d54efb5759ba2e286a3eb18f0017 344 PRINTS PR01755 Bacterial translocase SecF protein signature 281 296 1.4E-24 T 22-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial HRM2_RS13490 2ac3d54efb5759ba2e286a3eb18f0017 344 PRINTS PR01755 Bacterial translocase SecF protein signature 38 53 1.4E-24 T 22-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial HRM2_RS13490 2ac3d54efb5759ba2e286a3eb18f0017 344 PRINTS PR01755 Bacterial translocase SecF protein signature 249 267 1.4E-24 T 22-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial HRM2_RS16070 5d65ff8754ac47a36dbf5549d1526c12 262 Gene3D G3DSA:1.10.3720.10 9 260 6.4E-44 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS16070 5d65ff8754ac47a36dbf5549d1526c12 262 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 71 257 2.5E-16 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS16070 5d65ff8754ac47a36dbf5549d1526c12 262 SUPERFAMILY SSF161098 9 256 1.13E-46 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS16070 5d65ff8754ac47a36dbf5549d1526c12 262 PANTHER PTHR30183 9 261 1.6E-51 T 22-04-2016 HRM2_RS04080 e93d85d835740855ebeefbcffe800ce4 242 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS04080 e93d85d835740855ebeefbcffe800ce4 242 SUPERFAMILY SSF52540 31 220 5.2E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04080 e93d85d835740855ebeefbcffe800ce4 242 SMART SM00382 35 226 5.2E-17 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS04080 e93d85d835740855ebeefbcffe800ce4 242 Pfam PF00005 ABC transporter 31 177 8.4E-27 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS04080 e93d85d835740855ebeefbcffe800ce4 242 Gene3D G3DSA:3.40.50.300 31 222 2.9E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04080 e93d85d835740855ebeefbcffe800ce4 242 PANTHER PTHR24220 31 219 6.5E-59 T 22-04-2016 HRM2_RS18790 bf538d5c829b8fba3870207dd394d942 289 SUPERFAMILY SSF161098 90 273 1.31E-38 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS18790 bf538d5c829b8fba3870207dd394d942 289 PANTHER PTHR30177:SF10 9 277 9.7E-96 T 22-04-2016 HRM2_RS18790 bf538d5c829b8fba3870207dd394d942 289 PANTHER PTHR30177 9 277 9.7E-96 T 22-04-2016 HRM2_RS18790 bf538d5c829b8fba3870207dd394d942 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 269 6.0E-23 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS18790 bf538d5c829b8fba3870207dd394d942 289 Gene3D G3DSA:1.10.3720.10 57 270 3.8E-36 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS03420 808eed19640476765b04bc2677e55e81 244 SUPERFAMILY SSF53335 21 198 4.38E-31 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS03420 808eed19640476765b04bc2677e55e81 244 PANTHER PTHR10108 22 186 9.9E-16 T 22-04-2016 HRM2_RS03420 808eed19640476765b04bc2677e55e81 244 Gene3D G3DSA:3.40.50.150 23 190 9.9E-30 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS03420 808eed19640476765b04bc2677e55e81 244 Pfam PF08241 Methyltransferase domain 47 135 3.5E-14 T 22-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 HRM2_RS14185 12add05cf50b6f62f30f261ab85e99e2 594 PANTHER PTHR24096:SF193 15 594 2.9E-164 T 22-04-2016 HRM2_RS14185 12add05cf50b6f62f30f261ab85e99e2 594 SUPERFAMILY SSF56801 336 594 9.94E-101 T 22-04-2016 HRM2_RS14185 12add05cf50b6f62f30f261ab85e99e2 594 SUPERFAMILY SSF56801 8 285 9.94E-101 T 22-04-2016 HRM2_RS14185 12add05cf50b6f62f30f261ab85e99e2 594 Gene3D G3DSA:3.40.50.980 333 393 1.5E-26 T 22-04-2016 HRM2_RS14185 12add05cf50b6f62f30f261ab85e99e2 594 Gene3D G3DSA:3.40.50.980 189 280 1.5E-26 T 22-04-2016 HRM2_RS14185 12add05cf50b6f62f30f261ab85e99e2 594 PANTHER PTHR24096 15 594 2.9E-164 T 22-04-2016 HRM2_RS14185 12add05cf50b6f62f30f261ab85e99e2 594 Gene3D G3DSA:2.30.38.10 405 460 1.9E-18 T 22-04-2016 HRM2_RS14185 12add05cf50b6f62f30f261ab85e99e2 594 Gene3D G3DSA:3.40.50.980 6 188 3.8E-28 T 22-04-2016 HRM2_RS14185 12add05cf50b6f62f30f261ab85e99e2 594 Pfam PF00501 AMP-binding enzyme 16 466 1.6E-81 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS14185 12add05cf50b6f62f30f261ab85e99e2 594 Gene3D G3DSA:3.30.300.30 464 582 4.3E-4 T 22-04-2016 HRM2_RS14185 12add05cf50b6f62f30f261ab85e99e2 594 ProSitePatterns PS00455 Putative AMP-binding domain signature. 183 194 - T 22-04-2016 IPR020845 AMP-binding, conserved site HRM2_RS17670 8afbc6ec51e9bbd0d775f9b64389e3af 321 Gene3D G3DSA:3.40.50.300 105 310 1.9E-88 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17670 8afbc6ec51e9bbd0d775f9b64389e3af 321 PANTHER PTHR30473 3 311 3.9E-151 T 22-04-2016 HRM2_RS17670 8afbc6ec51e9bbd0d775f9b64389e3af 321 SUPERFAMILY SSF52540 28 79 2.55E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17670 8afbc6ec51e9bbd0d775f9b64389e3af 321 SUPERFAMILY SSF52540 106 287 2.55E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17670 8afbc6ec51e9bbd0d775f9b64389e3af 321 Pfam PF02562 PhoH-like protein 107 310 3.0E-94 T 22-04-2016 IPR003714 PhoH-like protein GO:0005524 HRM2_RS17670 8afbc6ec51e9bbd0d775f9b64389e3af 321 PANTHER PTHR30473:SF1 3 311 3.9E-151 T 22-04-2016 HRM2_RS02475 ac86aaac3d536b021e5b68ae867c8786 387 PANTHER PTHR30486:SF5 2 387 6.1E-130 T 22-04-2016 HRM2_RS02475 ac86aaac3d536b021e5b68ae867c8786 387 SMART SM00382 133 269 8.2E-4 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS02475 ac86aaac3d536b021e5b68ae867c8786 387 Gene3D G3DSA:3.40.50.300 112 351 3.1E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02475 ac86aaac3d536b021e5b68ae867c8786 387 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 6 354 5.3E-112 T 22-04-2016 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 HRM2_RS02475 ac86aaac3d536b021e5b68ae867c8786 387 PANTHER PTHR30486 2 387 6.1E-130 T 22-04-2016 HRM2_RS02475 ac86aaac3d536b021e5b68ae867c8786 387 Pfam PF00437 Type II/IV secretion system protein 88 275 2.0E-40 T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 HRM2_RS02475 ac86aaac3d536b021e5b68ae867c8786 387 SUPERFAMILY SSF52540 59 348 1.2E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17515 a53405bde49429f728c4e33e0fb2d1d2 742 Pfam PF00270 DEAD/DEAH box helicase 62 209 2.1E-13 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HRM2_RS17515 a53405bde49429f728c4e33e0fb2d1d2 742 Gene3D G3DSA:3.40.50.300 292 323 1.4E-14 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17515 a53405bde49429f728c4e33e0fb2d1d2 742 Gene3D G3DSA:3.40.50.300 360 446 1.4E-14 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17515 a53405bde49429f728c4e33e0fb2d1d2 742 SMART SM00490 348 440 1.4E-9 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS17515 a53405bde49429f728c4e33e0fb2d1d2 742 SMART SM01142 545 718 4.5E-34 T 22-04-2016 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal HRM2_RS17515 a53405bde49429f728c4e33e0fb2d1d2 742 SMART SM00487 55 242 7.9E-21 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS17515 a53405bde49429f728c4e33e0fb2d1d2 742 Pfam PF08148 DSHCT (NUC185) domain 548 712 6.4E-26 T 22-04-2016 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal HRM2_RS17515 a53405bde49429f728c4e33e0fb2d1d2 742 SUPERFAMILY SSF52540 274 323 5.64E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17515 a53405bde49429f728c4e33e0fb2d1d2 742 SUPERFAMILY SSF52540 71 211 5.64E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17515 a53405bde49429f728c4e33e0fb2d1d2 742 SUPERFAMILY SSF52540 360 450 5.64E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17515 a53405bde49429f728c4e33e0fb2d1d2 742 Gene3D G3DSA:3.40.50.300 55 220 8.9E-33 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23775 8d9826d135e4b05cba5eb19e6cb40299 360 SUPERFAMILY SSF56349 59 351 8.24E-68 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HRM2_RS23775 8d9826d135e4b05cba5eb19e6cb40299 360 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 60 113 1.0E-10 T 22-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 HRM2_RS23775 8d9826d135e4b05cba5eb19e6cb40299 360 PANTHER PTHR30349:SF20 59 357 3.2E-50 T 22-04-2016 HRM2_RS23775 8d9826d135e4b05cba5eb19e6cb40299 360 Pfam PF00589 Phage integrase family 171 343 1.7E-23 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS23775 8d9826d135e4b05cba5eb19e6cb40299 360 PANTHER PTHR30349 59 357 3.2E-50 T 22-04-2016 HRM2_RS23775 8d9826d135e4b05cba5eb19e6cb40299 360 Gene3D G3DSA:1.10.150.130 60 158 4.2E-17 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal HRM2_RS23775 8d9826d135e4b05cba5eb19e6cb40299 360 Gene3D G3DSA:1.10.443.10 170 351 1.6E-42 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS08160 b01509387e449a08f13a6b03c2ae679b 440 PANTHER PTHR30538 119 425 5.2E-102 T 22-04-2016 HRM2_RS08160 b01509387e449a08f13a6b03c2ae679b 440 PANTHER PTHR30538 6 91 5.2E-102 T 22-04-2016 HRM2_RS08160 b01509387e449a08f13a6b03c2ae679b 440 SUPERFAMILY SSF102114 127 350 5.89E-8 T 22-04-2016 HRM2_RS08160 b01509387e449a08f13a6b03c2ae679b 440 PANTHER PTHR30538:SF0 119 425 5.2E-102 T 22-04-2016 HRM2_RS08160 b01509387e449a08f13a6b03c2ae679b 440 PANTHER PTHR30538:SF0 6 91 5.2E-102 T 22-04-2016 HRM2_RS08160 b01509387e449a08f13a6b03c2ae679b 440 Gene3D G3DSA:3.20.20.70 140 283 1.2E-4 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS14970 f1e50f19f139776dc02e121396d26993 393 Gene3D G3DSA:3.40.710.10 345 382 2.8E-5 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HRM2_RS14970 f1e50f19f139776dc02e121396d26993 393 Gene3D G3DSA:3.40.710.10 208 333 6.3E-25 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HRM2_RS14970 f1e50f19f139776dc02e121396d26993 393 ProSitePatterns PS00337 Beta-lactamase class-D active site. 53 63 - T 22-04-2016 IPR002137 Beta-lactamase, class-D active site GO:0008800|GO:0017001 KEGG: 00311+3.5.2.6 HRM2_RS14970 f1e50f19f139776dc02e121396d26993 393 SUPERFAMILY SSF56601 30 390 2.52E-51 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HRM2_RS14970 f1e50f19f139776dc02e121396d26993 393 PANTHER PTHR30023 29 392 7.4E-28 T 22-04-2016 HRM2_RS14970 f1e50f19f139776dc02e121396d26993 393 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 241 263 1.8E-15 T 22-04-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HRM2_RS14970 f1e50f19f139776dc02e121396d26993 393 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 313 327 1.8E-15 T 22-04-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HRM2_RS14970 f1e50f19f139776dc02e121396d26993 393 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 51 70 1.8E-15 T 22-04-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HRM2_RS14970 f1e50f19f139776dc02e121396d26993 393 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 298 312 1.8E-15 T 22-04-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HRM2_RS14970 f1e50f19f139776dc02e121396d26993 393 Gene3D G3DSA:3.40.710.10 29 70 6.3E-6 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HRM2_RS14970 f1e50f19f139776dc02e121396d26993 393 PANTHER PTHR30023:SF0 29 392 7.4E-28 T 22-04-2016 HRM2_RS14970 f1e50f19f139776dc02e121396d26993 393 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 202 333 5.3E-18 T 22-04-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HRM2_RS14970 f1e50f19f139776dc02e121396d26993 393 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 38 169 4.8E-18 T 22-04-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HRM2_RS13620 7da18ce19c52d44e46d4f9197f114285 171 SUPERFAMILY SSF55083 4 158 1.96E-48 T 22-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 HRM2_RS13620 7da18ce19c52d44e46d4f9197f114285 171 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 7 136 1.7E-36 T 22-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 HRM2_RS13620 7da18ce19c52d44e46d4f9197f114285 171 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 92 103 - T 22-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 HRM2_RS13620 7da18ce19c52d44e46d4f9197f114285 171 PANTHER PTHR20941 4 155 1.8E-60 T 22-04-2016 HRM2_RS13620 7da18ce19c52d44e46d4f9197f114285 171 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 8 136 2.2E-33 T 22-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 HRM2_RS13620 7da18ce19c52d44e46d4f9197f114285 171 Gene3D G3DSA:3.30.70.560 7 157 4.1E-51 T 22-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 HRM2_RS17540 80538fad3193204bef34c09351496e1d 361 Gene3D G3DSA:3.90.1150.10 260 361 6.4E-40 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS17540 80538fad3193204bef34c09351496e1d 361 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 6 360 1.6E-145 T 22-04-2016 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|UniPathway: UPA00135|UniPathway: UPA00244 HRM2_RS17540 80538fad3193204bef34c09351496e1d 361 Gene3D G3DSA:3.40.640.10 19 257 1.8E-95 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS17540 80538fad3193204bef34c09351496e1d 361 PANTHER PTHR21152 1 361 1.3E-160 T 22-04-2016 HRM2_RS17540 80538fad3193204bef34c09351496e1d 361 Pfam PF00266 Aminotransferase class-V 6 350 3.1E-48 T 22-04-2016 IPR000192 Aminotransferase class V domain HRM2_RS17540 80538fad3193204bef34c09351496e1d 361 SUPERFAMILY SSF53383 4 360 9.04E-108 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS17540 80538fad3193204bef34c09351496e1d 361 PIRSF PIRSF000525 1 361 1.6E-140 T 22-04-2016 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|UniPathway: UPA00135|UniPathway: UPA00244 HRM2_RS17540 80538fad3193204bef34c09351496e1d 361 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 4 361 46.443 T 22-04-2016 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|UniPathway: UPA00135|UniPathway: UPA00244 HRM2_RS17540 80538fad3193204bef34c09351496e1d 361 PANTHER PTHR21152:SF1 1 361 1.3E-160 T 22-04-2016 HRM2_RS04750 94109e049dac9a5f208f392c15d54d33 605 PRINTS PR01607 Apyrase family signature 238 261 9.7E-28 T 22-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 HRM2_RS04750 94109e049dac9a5f208f392c15d54d33 605 PRINTS PR01607 Apyrase family signature 441 464 9.7E-28 T 22-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 HRM2_RS04750 94109e049dac9a5f208f392c15d54d33 605 PRINTS PR01607 Apyrase family signature 37 55 9.7E-28 T 22-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 HRM2_RS04750 94109e049dac9a5f208f392c15d54d33 605 PRINTS PR01607 Apyrase family signature 283 303 9.7E-28 T 22-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 HRM2_RS04750 94109e049dac9a5f208f392c15d54d33 605 PRINTS PR01607 Apyrase family signature 522 541 9.7E-28 T 22-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 HRM2_RS04750 94109e049dac9a5f208f392c15d54d33 605 PRINTS PR01607 Apyrase family signature 219 236 9.7E-28 T 22-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 HRM2_RS04750 94109e049dac9a5f208f392c15d54d33 605 PANTHER PTHR11575:SF7 39 306 1.7E-119 T 22-04-2016 HRM2_RS04750 94109e049dac9a5f208f392c15d54d33 605 PANTHER PTHR11575:SF7 344 573 1.7E-119 T 22-04-2016 HRM2_RS04750 94109e049dac9a5f208f392c15d54d33 605 Gene3D G3DSA:3.90.780.10 378 573 6.4E-39 T 22-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 HRM2_RS04750 94109e049dac9a5f208f392c15d54d33 605 Gene3D G3DSA:3.60.21.10 355 375 2.5E-86 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS04750 94109e049dac9a5f208f392c15d54d33 605 Gene3D G3DSA:3.60.21.10 36 321 2.5E-86 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS04750 94109e049dac9a5f208f392c15d54d33 605 TIGRFAM TIGR01530 nadN: NAD nucleotidase 39 573 8.8E-138 T 22-04-2016 IPR006420 NAD pyrophosphatase/5-nucleotidase NadN GO:0008253|GO:0009166 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 HRM2_RS04750 94109e049dac9a5f208f392c15d54d33 605 SUPERFAMILY SSF56300 38 327 8.54E-79 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS04750 94109e049dac9a5f208f392c15d54d33 605 SUPERFAMILY SSF56300 355 374 8.54E-79 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS04750 94109e049dac9a5f208f392c15d54d33 605 Pfam PF00149 Calcineurin-like phosphoesterase 39 254 1.6E-8 T 22-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 HRM2_RS04750 94109e049dac9a5f208f392c15d54d33 605 Pfam PF02872 5'-nucleotidase, C-terminal domain 407 548 4.4E-31 T 22-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 HRM2_RS04750 94109e049dac9a5f208f392c15d54d33 605 SUPERFAMILY SSF55816 378 575 4.71E-41 T 22-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 HRM2_RS04750 94109e049dac9a5f208f392c15d54d33 605 ProSitePatterns PS00786 5'-nucleotidase signature 2. 121 132 - T 22-04-2016 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 HRM2_RS04750 94109e049dac9a5f208f392c15d54d33 605 PANTHER PTHR11575 39 306 1.7E-119 T 22-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 HRM2_RS04750 94109e049dac9a5f208f392c15d54d33 605 PANTHER PTHR11575 344 573 1.7E-119 T 22-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 HRM2_RS16220 adb8146887ae43e4529550137b5b0476 132 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 87 118 1.2E-5 T 22-04-2016 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 HRM2_RS16220 adb8146887ae43e4529550137b5b0476 132 Pfam PF00578 AhpC/TSA family 2 65 1.8E-10 T 22-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 HRM2_RS16220 adb8146887ae43e4529550137b5b0476 132 PANTHER PTHR10681 1 132 4.9E-26 T 22-04-2016 HRM2_RS16220 adb8146887ae43e4529550137b5b0476 132 PANTHER PTHR10681:SF121 1 132 4.9E-26 T 22-04-2016 HRM2_RS16220 adb8146887ae43e4529550137b5b0476 132 SUPERFAMILY SSF52833 2 126 2.05E-27 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS16220 adb8146887ae43e4529550137b5b0476 132 Gene3D G3DSA:3.40.30.10 1 123 6.1E-30 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS21630 d874201c96e616d0b1635d41a39665d7 379 SUPERFAMILY SSF50952 45 377 8.76E-42 T 22-04-2016 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 HRM2_RS21630 d874201c96e616d0b1635d41a39665d7 379 Gene3D G3DSA:2.120.10.30 12 377 3.1E-101 T 22-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like HRM2_RS21630 d874201c96e616d0b1635d41a39665d7 379 Pfam PF07995 Glucose / Sorbosone dehydrogenase 46 374 1.7E-129 T 22-04-2016 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 HRM2_RS21630 d874201c96e616d0b1635d41a39665d7 379 PANTHER PTHR19328 46 377 5.9E-65 T 22-04-2016 HRM2_RS23530 6e831d3a9662b64d015e0f99a82dd428 108 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 36 82 4.2E-10 T 22-04-2016 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 HRM2_RS23530 6e831d3a9662b64d015e0f99a82dd428 108 SUPERFAMILY SSF69118 7 106 6.54E-21 T 22-04-2016 IPR029032 AhpD-like HRM2_RS23530 6e831d3a9662b64d015e0f99a82dd428 108 PANTHER PTHR33930 9 105 1.4E-16 T 22-04-2016 HRM2_RS23530 6e831d3a9662b64d015e0f99a82dd428 108 Pfam PF02627 Carboxymuconolactone decarboxylase family 25 97 2.3E-12 T 22-04-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 HRM2_RS23530 6e831d3a9662b64d015e0f99a82dd428 108 PANTHER PTHR33930:SF2 9 105 1.4E-16 T 22-04-2016 HRM2_RS23530 6e831d3a9662b64d015e0f99a82dd428 108 Gene3D G3DSA:1.20.1290.10 10 101 8.1E-22 T 22-04-2016 IPR029032 AhpD-like HRM2_RS08485 ba2ec844020f70741c916773805290ad 415 PANTHER PTHR15184:SF34 78 414 4.1E-186 T 22-04-2016 HRM2_RS08485 ba2ec844020f70741c916773805290ad 415 SUPERFAMILY SSF50249 49 125 6.85E-30 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS08485 ba2ec844020f70741c916773805290ad 415 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 156 360 1.9E-22 T 22-04-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS08485 ba2ec844020f70741c916773805290ad 415 Pfam PF07498 Rho termination factor, N-terminal domain 5 46 8.4E-13 T 22-04-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 HRM2_RS08485 ba2ec844020f70741c916773805290ad 415 Gene3D G3DSA:1.10.720.10 1 46 1.5E-15 T 22-04-2016 HRM2_RS08485 ba2ec844020f70741c916773805290ad 415 Gene3D G3DSA:2.40.50.140 49 117 7.3E-36 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS08485 ba2ec844020f70741c916773805290ad 415 SMART SM00959 5 47 3.9E-12 T 22-04-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 HRM2_RS08485 ba2ec844020f70741c916773805290ad 415 PANTHER PTHR15184 78 414 4.1E-186 T 22-04-2016 HRM2_RS08485 ba2ec844020f70741c916773805290ad 415 Gene3D G3DSA:3.40.50.300 132 413 1.7E-101 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08485 ba2ec844020f70741c916773805290ad 415 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 2.7E-32 T 22-04-2016 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 HRM2_RS08485 ba2ec844020f70741c916773805290ad 415 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 415 236.588 T 22-04-2016 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 HRM2_RS08485 ba2ec844020f70741c916773805290ad 415 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 414 4.5E-208 T 22-04-2016 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 HRM2_RS08485 ba2ec844020f70741c916773805290ad 415 SMART SM00357 52 118 7.8E-20 T 22-04-2016 IPR011129 Cold shock protein GO:0003676 HRM2_RS08485 ba2ec844020f70741c916773805290ad 415 SUPERFAMILY SSF52540 90 368 4.75E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08485 ba2ec844020f70741c916773805290ad 415 SUPERFAMILY SSF68912 1 46 9.81E-11 T 22-04-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 HRM2_RS08485 ba2ec844020f70741c916773805290ad 415 SMART SM00382 167 352 5.0E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS07610 8a1a9d29aea2eda2ea5c21c240547dd7 267 Gene3D G3DSA:3.40.190.10 146 213 5.4E-6 T 22-04-2016 HRM2_RS07610 8a1a9d29aea2eda2ea5c21c240547dd7 267 SMART SM00062 36 262 9.3E-42 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS07610 8a1a9d29aea2eda2ea5c21c240547dd7 267 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 37 258 1.8E-42 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS07610 8a1a9d29aea2eda2ea5c21c240547dd7 267 SUPERFAMILY SSF53850 8 258 2.72E-50 T 22-04-2016 HRM2_RS07610 8a1a9d29aea2eda2ea5c21c240547dd7 267 PANTHER PTHR18966 22 260 2.4E-27 T 22-04-2016 HRM2_RS07610 8a1a9d29aea2eda2ea5c21c240547dd7 267 PANTHER PTHR18966:SF191 22 260 2.4E-27 T 22-04-2016 HRM2_RS07610 8a1a9d29aea2eda2ea5c21c240547dd7 267 Gene3D G3DSA:3.40.190.10 16 145 1.7E-33 T 22-04-2016 HRM2_RS11540 a2dc16dcebe49848e660468c31bc8943 479 SMART SM00997 239 401 1.1E-114 T 22-04-2016 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 HRM2_RS11540 a2dc16dcebe49848e660468c31bc8943 479 PANTHER PTHR23420 189 479 0.0 T 22-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 HRM2_RS11540 a2dc16dcebe49848e660468c31bc8943 479 PANTHER PTHR23420 13 152 0.0 T 22-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 HRM2_RS11540 a2dc16dcebe49848e660468c31bc8943 479 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 17 471 3.7E-188 T 22-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 HRM2_RS11540 a2dc16dcebe49848e660468c31bc8943 479 Gene3D G3DSA:3.40.50.1480 402 479 2.4E-33 T 22-04-2016 HRM2_RS11540 a2dc16dcebe49848e660468c31bc8943 479 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 239 401 3.0E-82 T 22-04-2016 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 HRM2_RS11540 a2dc16dcebe49848e660468c31bc8943 479 Gene3D G3DSA:3.40.50.1480 190 277 5.5E-118 T 22-04-2016 HRM2_RS11540 a2dc16dcebe49848e660468c31bc8943 479 Gene3D G3DSA:3.40.50.1480 15 153 5.5E-118 T 22-04-2016 HRM2_RS11540 a2dc16dcebe49848e660468c31bc8943 479 Gene3D G3DSA:3.40.50.720 278 356 1.0E-11 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS11540 a2dc16dcebe49848e660468c31bc8943 479 SUPERFAMILY SSF51735 239 401 6.77E-79 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS11540 a2dc16dcebe49848e660468c31bc8943 479 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 12 471 48.435 T 22-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 HRM2_RS11540 a2dc16dcebe49848e660468c31bc8943 479 PIRSF PIRSF001109 6 479 2.8E-187 T 22-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 HRM2_RS11540 a2dc16dcebe49848e660468c31bc8943 479 SUPERFAMILY SSF52283 402 479 2.38E-108 T 22-04-2016 HRM2_RS11540 a2dc16dcebe49848e660468c31bc8943 479 SUPERFAMILY SSF52283 15 154 2.38E-108 T 22-04-2016 HRM2_RS11540 a2dc16dcebe49848e660468c31bc8943 479 SUPERFAMILY SSF52283 191 238 2.38E-108 T 22-04-2016 HRM2_RS11540 a2dc16dcebe49848e660468c31bc8943 479 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 261 278 - T 22-04-2016 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 HRM2_RS11540 a2dc16dcebe49848e660468c31bc8943 479 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 16 478 5.2E-140 T 22-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 HRM2_RS11540 a2dc16dcebe49848e660468c31bc8943 479 SMART SM00996 16 478 0.0 T 22-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 HRM2_RS20210 08d484686a4a84a4c6b82a326d191662 821 Pfam PF00384 Molybdopterin oxidoreductase 2 447 3.1E-26 T 22-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 HRM2_RS20210 08d484686a4a84a4c6b82a326d191662 821 Gene3D G3DSA:2.40.40.20 622 820 1.4E-43 T 22-04-2016 HRM2_RS20210 08d484686a4a84a4c6b82a326d191662 821 SUPERFAMILY SSF53706 1 653 5.23E-223 T 22-04-2016 HRM2_RS20210 08d484686a4a84a4c6b82a326d191662 821 Pfam PF01568 Molydopterin dinucleotide binding domain 696 814 6.1E-17 T 22-04-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 HRM2_RS20210 08d484686a4a84a4c6b82a326d191662 821 Gene3D G3DSA:3.40.228.10 1 104 5.2E-72 T 22-04-2016 HRM2_RS20210 08d484686a4a84a4c6b82a326d191662 821 Gene3D G3DSA:3.40.228.10 153 263 5.2E-72 T 22-04-2016 HRM2_RS20210 08d484686a4a84a4c6b82a326d191662 821 PANTHER PTHR11615 123 186 6.0E-195 T 22-04-2016 HRM2_RS20210 08d484686a4a84a4c6b82a326d191662 821 PANTHER PTHR11615 682 820 6.0E-195 T 22-04-2016 HRM2_RS20210 08d484686a4a84a4c6b82a326d191662 821 PANTHER PTHR11615 577 661 6.0E-195 T 22-04-2016 HRM2_RS20210 08d484686a4a84a4c6b82a326d191662 821 PANTHER PTHR11615 326 482 6.0E-195 T 22-04-2016 HRM2_RS20210 08d484686a4a84a4c6b82a326d191662 821 PANTHER PTHR11615 1 104 6.0E-195 T 22-04-2016 HRM2_RS20210 08d484686a4a84a4c6b82a326d191662 821 PANTHER PTHR11615 214 283 6.0E-195 T 22-04-2016 HRM2_RS20210 08d484686a4a84a4c6b82a326d191662 821 TIGRFAM TIGR01553 formate-DH-alph: formate dehydrogenase-N alpha subunit 1 820 0.0 T 22-04-2016 IPR006443 Formate dehydrogenase-N, alpha subunit GO:0008863|GO:0009055|GO:0043546|GO:0045333|GO:0047111 HRM2_RS20210 08d484686a4a84a4c6b82a326d191662 821 PANTHER PTHR11615:SF126 123 186 6.0E-195 T 22-04-2016 HRM2_RS20210 08d484686a4a84a4c6b82a326d191662 821 PANTHER PTHR11615:SF126 682 820 6.0E-195 T 22-04-2016 HRM2_RS20210 08d484686a4a84a4c6b82a326d191662 821 PANTHER PTHR11615:SF126 577 661 6.0E-195 T 22-04-2016 HRM2_RS20210 08d484686a4a84a4c6b82a326d191662 821 PANTHER PTHR11615:SF126 326 482 6.0E-195 T 22-04-2016 HRM2_RS20210 08d484686a4a84a4c6b82a326d191662 821 PANTHER PTHR11615:SF126 1 104 6.0E-195 T 22-04-2016 HRM2_RS20210 08d484686a4a84a4c6b82a326d191662 821 PANTHER PTHR11615:SF126 214 283 6.0E-195 T 22-04-2016 HRM2_RS20210 08d484686a4a84a4c6b82a326d191662 821 SUPERFAMILY SSF50692 637 662 1.45E-40 T 22-04-2016 IPR009010 Aspartate decarboxylase-like domain HRM2_RS20210 08d484686a4a84a4c6b82a326d191662 821 SUPERFAMILY SSF50692 689 820 1.45E-40 T 22-04-2016 IPR009010 Aspartate decarboxylase-like domain HRM2_RS20210 08d484686a4a84a4c6b82a326d191662 821 Gene3D G3DSA:3.40.50.740 326 471 3.4E-55 T 22-04-2016 HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 Gene3D G3DSA:3.40.50.300 351 398 1.0E-126 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 Gene3D G3DSA:3.40.50.300 3 228 1.0E-126 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 Pfam PF02810 SEC-C motif 822 839 3.1E-10 T 22-04-2016 IPR004027 SEC-C motif HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 Gene3D G3DSA:3.90.1440.10 230 350 4.3E-49 T 22-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 Gene3D G3DSA:3.40.50.300 399 572 1.1E-79 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 PANTHER PTHR30612 1 840 0.0 T 22-04-2016 HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 SUPERFAMILY SSF52540 350 397 1.51E-86 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 SUPERFAMILY SSF52540 4 228 1.51E-86 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 SUPERFAMILY SSF52540 399 571 2.07E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 ProSitePatterns PS01312 SecA family signature. 482 497 - T 22-04-2016 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 PRINTS PR00906 SecA protein signature 395 408 2.8E-69 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 PRINTS PR00906 SecA protein signature 117 127 2.8E-69 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 PRINTS PR00906 SecA protein signature 358 375 2.8E-69 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 PRINTS PR00906 SecA protein signature 170 190 2.8E-69 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 PRINTS PR00906 SecA protein signature 101 115 2.8E-69 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 PRINTS PR00906 SecA protein signature 63 87 2.8E-69 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 PRINTS PR00906 SecA protein signature 321 343 2.8E-69 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 SUPERFAMILY SSF81886 818 830 5.36E-76 T 22-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 SUPERFAMILY SSF81886 573 791 5.36E-76 T 22-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 Gene3D G3DSA:1.10.3060.10 601 782 5.7E-56 T 22-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 SMART SM00958 228 340 7.7E-70 T 22-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 SMART SM00957 6 384 4.0E-290 T 22-04-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 Pfam PF07517 SecA DEAD-like domain 7 384 4.7E-134 T 22-04-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 498 2.1E-238 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 Pfam PF07516 SecA Wing and Scaffold domain 570 780 6.5E-67 T 22-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 Pfam PF01043 SecA preprotein cross-linking domain 232 340 3.6E-42 T 22-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 783 20.361 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HRM2_RS13195 a7b90b8e88cb4d4db07633aef77de618 840 SUPERFAMILY SSF81767 227 350 9.68E-47 T 22-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 HRM2_RS17555 d1ed8415ead79ec1215d563eeab441c7 236 PANTHER PTHR30027 1 234 5.0E-38 T 22-04-2016 HRM2_RS17555 d1ed8415ead79ec1215d563eeab441c7 236 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 2 232 2.2E-28 T 22-04-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HRM2_RS17555 d1ed8415ead79ec1215d563eeab441c7 236 PIRSF PIRSF015601 1 236 6.4E-43 T 22-04-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HRM2_RS17555 d1ed8415ead79ec1215d563eeab441c7 236 Pfam PF04452 RNA methyltransferase 17 234 4.3E-43 T 22-04-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HRM2_RS17555 d1ed8415ead79ec1215d563eeab441c7 236 PANTHER PTHR30027:SF3 1 234 5.0E-38 T 22-04-2016 HRM2_RS17555 d1ed8415ead79ec1215d563eeab441c7 236 Gene3D G3DSA:3.40.1280.10 1 234 1.5E-57 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HRM2_RS17555 d1ed8415ead79ec1215d563eeab441c7 236 SUPERFAMILY SSF75217 72 235 5.67E-35 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases HRM2_RS09965 3c7a7b21b83780b3234db5f3ffa08a09 93 PANTHER PTHR33215:SF2 1 84 7.5E-12 T 22-04-2016 HRM2_RS09965 3c7a7b21b83780b3234db5f3ffa08a09 93 Gene3D G3DSA:1.10.10.60 14 86 3.5E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS09965 3c7a7b21b83780b3234db5f3ffa08a09 93 PANTHER PTHR33215 1 84 7.5E-12 T 22-04-2016 HRM2_RS09965 3c7a7b21b83780b3234db5f3ffa08a09 93 Pfam PF01527 Transposase 2 52 6.6E-6 T 22-04-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HRM2_RS09965 3c7a7b21b83780b3234db5f3ffa08a09 93 SUPERFAMILY SSF48295 2 60 3.71E-10 T 22-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 HRM2_RS21900 3c7a7b21b83780b3234db5f3ffa08a09 93 PANTHER PTHR33215:SF2 1 84 7.5E-12 T 22-04-2016 HRM2_RS21900 3c7a7b21b83780b3234db5f3ffa08a09 93 Gene3D G3DSA:1.10.10.60 14 86 3.5E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS21900 3c7a7b21b83780b3234db5f3ffa08a09 93 PANTHER PTHR33215 1 84 7.5E-12 T 22-04-2016 HRM2_RS21900 3c7a7b21b83780b3234db5f3ffa08a09 93 Pfam PF01527 Transposase 2 52 6.6E-6 T 22-04-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HRM2_RS21900 3c7a7b21b83780b3234db5f3ffa08a09 93 SUPERFAMILY SSF48295 2 60 3.71E-10 T 22-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 HRM2_RS17180 3c7a7b21b83780b3234db5f3ffa08a09 93 PANTHER PTHR33215:SF2 1 84 7.5E-12 T 22-04-2016 HRM2_RS17180 3c7a7b21b83780b3234db5f3ffa08a09 93 Gene3D G3DSA:1.10.10.60 14 86 3.5E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS17180 3c7a7b21b83780b3234db5f3ffa08a09 93 PANTHER PTHR33215 1 84 7.5E-12 T 22-04-2016 HRM2_RS17180 3c7a7b21b83780b3234db5f3ffa08a09 93 Pfam PF01527 Transposase 2 52 6.6E-6 T 22-04-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HRM2_RS17180 3c7a7b21b83780b3234db5f3ffa08a09 93 SUPERFAMILY SSF48295 2 60 3.71E-10 T 22-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 HRM2_RS03810 4ee12b88f2a3aa1314f1e744fe8cfaf3 393 Pfam PF13458 Periplasmic binding protein 27 357 4.4E-47 T 22-04-2016 IPR028081 Leucine-binding protein domain HRM2_RS03810 4ee12b88f2a3aa1314f1e744fe8cfaf3 393 Gene3D G3DSA:3.40.50.2300 156 306 2.6E-17 T 22-04-2016 HRM2_RS03810 4ee12b88f2a3aa1314f1e744fe8cfaf3 393 Gene3D G3DSA:3.40.50.2300 24 151 1.3E-38 T 22-04-2016 HRM2_RS03810 4ee12b88f2a3aa1314f1e744fe8cfaf3 393 Gene3D G3DSA:3.40.50.2300 307 353 1.3E-38 T 22-04-2016 HRM2_RS03810 4ee12b88f2a3aa1314f1e744fe8cfaf3 393 SUPERFAMILY SSF53822 26 379 8.75E-68 T 22-04-2016 IPR028082 Periplasmic binding protein-like I HRM2_RS03810 4ee12b88f2a3aa1314f1e744fe8cfaf3 393 PANTHER PTHR30483 5 393 1.1E-72 T 22-04-2016 HRM2_RS03810 4ee12b88f2a3aa1314f1e744fe8cfaf3 393 PANTHER PTHR30483:SF6 5 393 1.1E-72 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HRM2_RS25550 8c2725dc2b284cffc2c8c75c457026ed 922 SUPERFAMILY SSF55781 441 591 2.01E-9 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS25550 8c2725dc2b284cffc2c8c75c457026ed 922 Gene3D G3DSA:3.40.50.300 615 788 7.1E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS25550 8c2725dc2b284cffc2c8c75c457026ed 922 Gene3D G3DSA:3.30.450.40 440 585 6.1E-8 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS25550 8c2725dc2b284cffc2c8c75c457026ed 922 SUPERFAMILY SSF46689 830 921 7.17E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS25550 8c2725dc2b284cffc2c8c75c457026ed 922 Pfam PF00158 Sigma-54 interaction domain 617 784 1.2E-65 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS25550 8c2725dc2b284cffc2c8c75c457026ed 922 PANTHER PTHR32071 596 921 1.7E-136 T 22-04-2016 HRM2_RS25550 8c2725dc2b284cffc2c8c75c457026ed 922 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 830 839 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS25550 8c2725dc2b284cffc2c8c75c457026ed 922 SMART SM00382 637 780 3.9E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS25550 8c2725dc2b284cffc2c8c75c457026ed 922 Gene3D G3DSA:1.10.10.60 843 921 1.1E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS25550 8c2725dc2b284cffc2c8c75c457026ed 922 Gene3D G3DSA:1.25.40.10 72 170 1.3E-6 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS25550 8c2725dc2b284cffc2c8c75c457026ed 922 Gene3D G3DSA:1.25.40.10 185 292 2.5E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS25550 8c2725dc2b284cffc2c8c75c457026ed 922 Gene3D G3DSA:1.25.40.10 375 408 2.5E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS25550 8c2725dc2b284cffc2c8c75c457026ed 922 SUPERFAMILY SSF52540 616 855 3.14E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS25550 8c2725dc2b284cffc2c8c75c457026ed 922 SUPERFAMILY SSF48452 138 280 4.17E-11 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS25550 8c2725dc2b284cffc2c8c75c457026ed 922 SUPERFAMILY SSF48452 57 170 4.8E-8 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS25550 8c2725dc2b284cffc2c8c75c457026ed 922 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 703 718 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS25550 8c2725dc2b284cffc2c8c75c457026ed 922 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 641 654 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS25550 8c2725dc2b284cffc2c8c75c457026ed 922 Gene3D G3DSA:1.10.8.60 789 842 4.0E-21 T 22-04-2016 HRM2_RS25550 8c2725dc2b284cffc2c8c75c457026ed 922 Pfam PF02954 Bacterial regulatory protein, Fis family 875 917 4.6E-5 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS13850 7f40fd82cfc7607000e9cb66f5eec3a7 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 266 281 6.8E-61 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 HRM2_RS13850 7f40fd82cfc7607000e9cb66f5eec3a7 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 151 170 6.8E-61 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 HRM2_RS13850 7f40fd82cfc7607000e9cb66f5eec3a7 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 296 315 6.8E-61 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 HRM2_RS13850 7f40fd82cfc7607000e9cb66f5eec3a7 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 121 135 6.8E-61 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 HRM2_RS13850 7f40fd82cfc7607000e9cb66f5eec3a7 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 241 257 6.8E-61 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 HRM2_RS13850 7f40fd82cfc7607000e9cb66f5eec3a7 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 189 208 6.8E-61 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 HRM2_RS13850 7f40fd82cfc7607000e9cb66f5eec3a7 327 PIRSF PIRSF001415 1 325 3.1E-150 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 HRM2_RS13850 7f40fd82cfc7607000e9cb66f5eec3a7 327 PANTHER PTHR11458 1 320 3.0E-184 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 HRM2_RS13850 7f40fd82cfc7607000e9cb66f5eec3a7 327 Gene3D G3DSA:3.20.20.70 2 323 3.6E-150 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS13850 7f40fd82cfc7607000e9cb66f5eec3a7 327 SMART SM01004 3 322 8.1E-229 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 HRM2_RS13850 7f40fd82cfc7607000e9cb66f5eec3a7 327 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 241 253 - T 22-04-2016 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 HRM2_RS13850 7f40fd82cfc7607000e9cb66f5eec3a7 327 Pfam PF00490 Delta-aminolevulinic acid dehydratase 6 320 3.9E-150 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 HRM2_RS13850 7f40fd82cfc7607000e9cb66f5eec3a7 327 SUPERFAMILY SSF51569 2 323 8.35E-143 T 22-04-2016 HRM2_RS08190 7c998c3b5b441523bb49f269d31e6b4c 233 Gene3D G3DSA:3.40.50.150 28 223 9.8E-59 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS08190 7c998c3b5b441523bb49f269d31e6b4c 233 PANTHER PTHR18895 14 223 3.3E-48 T 22-04-2016 HRM2_RS08190 7c998c3b5b441523bb49f269d31e6b4c 233 Pfam PF05175 Methyltransferase small domain 31 125 2.0E-12 T 22-04-2016 IPR007848 Methyltransferase small domain GO:0008168 HRM2_RS08190 7c998c3b5b441523bb49f269d31e6b4c 233 SUPERFAMILY SSF53335 19 192 3.47E-33 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS08190 7c998c3b5b441523bb49f269d31e6b4c 233 PANTHER PTHR18895:SF75 14 223 3.3E-48 T 22-04-2016 HRM2_RS08190 7c998c3b5b441523bb49f269d31e6b4c 233 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 115 121 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HRM2_RS09280 f7775dc98de5edf981c40fc7a02b0fea 151 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 22-04-2016 IPR020070 Ribosomal protein L9, N-terminal HRM2_RS09280 f7775dc98de5edf981c40fc7a02b0fea 151 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 3.1E-19 T 22-04-2016 IPR020070 Ribosomal protein L9, N-terminal HRM2_RS09280 f7775dc98de5edf981c40fc7a02b0fea 151 Pfam PF03948 Ribosomal protein L9, C-terminal domain 65 145 1.6E-25 T 22-04-2016 IPR020069 Ribosomal protein L9, C-terminal HRM2_RS09280 f7775dc98de5edf981c40fc7a02b0fea 151 PANTHER PTHR21368 1 148 6.7E-44 T 22-04-2016 IPR000244 Ribosomal protein L9 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS09280 f7775dc98de5edf981c40fc7a02b0fea 151 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 8.4E-41 T 22-04-2016 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS09280 f7775dc98de5edf981c40fc7a02b0fea 151 SUPERFAMILY SSF55653 58 147 8.63E-24 T 22-04-2016 IPR020069 Ribosomal protein L9, C-terminal HRM2_RS09280 f7775dc98de5edf981c40fc7a02b0fea 151 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 147 22.749 T 22-04-2016 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS09280 f7775dc98de5edf981c40fc7a02b0fea 151 Gene3D G3DSA:3.40.5.10 1 51 1.7E-19 T 22-04-2016 IPR020070 Ribosomal protein L9, N-terminal HRM2_RS09280 f7775dc98de5edf981c40fc7a02b0fea 151 SUPERFAMILY SSF55658 1 55 1.13E-15 T 22-04-2016 IPR009027 Ribosomal protein L9/RNase H1, N-terminal HRM2_RS09280 f7775dc98de5edf981c40fc7a02b0fea 151 Gene3D G3DSA:3.10.430.100 61 147 7.4E-27 T 22-04-2016 IPR020069 Ribosomal protein L9, C-terminal HRM2_RS16450 4e5dd0295f00a2a2bb17cdde854039d8 176 Gene3D G3DSA:1.10.60.30 106 173 3.8E-24 T 22-04-2016 IPR023153 PSPTO4464-like domain HRM2_RS16450 4e5dd0295f00a2a2bb17cdde854039d8 176 SUPERFAMILY SSF158710 28 171 4.18E-45 T 22-04-2016 HRM2_RS16450 4e5dd0295f00a2a2bb17cdde854039d8 176 Pfam PF04751 Protein of unknown function (DUF615) 16 168 1.9E-44 T 22-04-2016 IPR006839 Ribosome-associated, YjgA HRM2_RS16450 4e5dd0295f00a2a2bb17cdde854039d8 176 PANTHER PTHR38101 1 172 1.0E-39 T 22-04-2016 HRM2_RS16450 4e5dd0295f00a2a2bb17cdde854039d8 176 PANTHER PTHR38101:SF1 1 172 1.0E-39 T 22-04-2016 HRM2_RS16450 4e5dd0295f00a2a2bb17cdde854039d8 176 Gene3D G3DSA:1.10.60.30 28 97 9.5E-24 T 22-04-2016 IPR023153 PSPTO4464-like domain HRM2_RS16450 4e5dd0295f00a2a2bb17cdde854039d8 176 PIRSF PIRSF016183 2 175 3.6E-49 T 22-04-2016 IPR006839 Ribosome-associated, YjgA HRM2_RS06385 a2bfc9c932574ef4eb370bda9974048b 179 SUPERFAMILY SSF51161 2 165 6.1E-46 T 22-04-2016 IPR011004 Trimeric LpxA-like HRM2_RS06385 a2bfc9c932574ef4eb370bda9974048b 179 Gene3D G3DSA:2.160.10.10 2 168 1.1E-46 T 22-04-2016 HRM2_RS06385 a2bfc9c932574ef4eb370bda9974048b 179 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 12 45 6.8E-6 T 22-04-2016 IPR001451 Hexapeptide repeat HRM2_RS06385 a2bfc9c932574ef4eb370bda9974048b 179 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 121 5.4E-9 T 22-04-2016 IPR001451 Hexapeptide repeat HRM2_RS06385 a2bfc9c932574ef4eb370bda9974048b 179 PANTHER PTHR13061 1 168 2.6E-63 T 22-04-2016 HRM2_RS24385 1465daef35b63503d1c10488abba44db 285 PANTHER PTHR22911 4 285 9.0E-53 T 22-04-2016 HRM2_RS24385 1465daef35b63503d1c10488abba44db 285 SUPERFAMILY SSF103481 39 140 5.36E-17 T 22-04-2016 HRM2_RS24385 1465daef35b63503d1c10488abba44db 285 SUPERFAMILY SSF103481 189 284 8.24E-16 T 22-04-2016 HRM2_RS24385 1465daef35b63503d1c10488abba44db 285 Pfam PF00892 EamA-like transporter family 154 283 3.3E-22 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS24385 1465daef35b63503d1c10488abba44db 285 Pfam PF00892 EamA-like transporter family 4 137 5.7E-25 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS13365 4b2f342dccd0e59743f15a5e8ade7e19 174 Gene3D G3DSA:3.90.45.10 5 169 3.9E-58 T 22-04-2016 IPR023635 Peptide deformylase HRM2_RS13365 4b2f342dccd0e59743f15a5e8ade7e19 174 PIRSF PIRSF004749 1 173 4.4E-52 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 HRM2_RS13365 4b2f342dccd0e59743f15a5e8ade7e19 174 Hamap MF_00163 Peptide deformylase [def]. 2 170 27.919 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 HRM2_RS13365 4b2f342dccd0e59743f15a5e8ade7e19 174 PRINTS PR01576 Peptide deformylase signature 109 127 5.2E-35 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 HRM2_RS13365 4b2f342dccd0e59743f15a5e8ade7e19 174 PRINTS PR01576 Peptide deformylase signature 33 62 5.2E-35 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 HRM2_RS13365 4b2f342dccd0e59743f15a5e8ade7e19 174 PRINTS PR01576 Peptide deformylase signature 128 157 5.2E-35 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 HRM2_RS13365 4b2f342dccd0e59743f15a5e8ade7e19 174 PRINTS PR01576 Peptide deformylase signature 97 108 5.2E-35 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 HRM2_RS13365 4b2f342dccd0e59743f15a5e8ade7e19 174 SUPERFAMILY SSF56420 3 169 8.51E-56 T 22-04-2016 IPR023635 Peptide deformylase HRM2_RS13365 4b2f342dccd0e59743f15a5e8ade7e19 174 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 167 7.6E-45 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 HRM2_RS13365 4b2f342dccd0e59743f15a5e8ade7e19 174 Pfam PF01327 Polypeptide deformylase 5 160 1.2E-49 T 22-04-2016 IPR023635 Peptide deformylase HRM2_RS13365 4b2f342dccd0e59743f15a5e8ade7e19 174 PANTHER PTHR10458 1 169 2.4E-59 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 HRM2_RS15385 be52449ad53b957c27ef164d68c462f1 299 Pfam PF00152 tRNA synthetases class II (D, K and N) 3 295 3.2E-45 T 22-04-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS15385 be52449ad53b957c27ef164d68c462f1 299 Gene3D G3DSA:3.30.930.10 4 294 1.0E-66 T 22-04-2016 HRM2_RS15385 be52449ad53b957c27ef164d68c462f1 299 PANTHER PTHR22594:SF7 5 294 3.2E-105 T 22-04-2016 IPR004525 Elongation factor P--(R)-beta-lysine ligase GO:0004824|GO:0005524|GO:0005737|GO:0006430 HRM2_RS15385 be52449ad53b957c27ef164d68c462f1 299 SUPERFAMILY SSF55681 4 294 2.39E-72 T 22-04-2016 HRM2_RS15385 be52449ad53b957c27ef164d68c462f1 299 TIGRFAM TIGR00462 genX: EF-P lysine aminoacylase GenX 7 294 2.6E-99 T 22-04-2016 IPR004525 Elongation factor P--(R)-beta-lysine ligase GO:0004824|GO:0005524|GO:0005737|GO:0006430 HRM2_RS15385 be52449ad53b957c27ef164d68c462f1 299 PANTHER PTHR22594 5 294 3.2E-105 T 22-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS00140 ed8dca4c32fd1cb0bc72c45b9a797735 236 PANTHER PTHR10859:SF92 2 187 8.0E-24 T 22-04-2016 HRM2_RS00140 ed8dca4c32fd1cb0bc72c45b9a797735 236 Pfam PF00535 Glycosyl transferase family 2 13 133 1.1E-9 T 22-04-2016 IPR001173 Glycosyltransferase 2-like HRM2_RS00140 ed8dca4c32fd1cb0bc72c45b9a797735 236 Gene3D G3DSA:3.90.550.10 20 197 6.5E-14 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS00140 ed8dca4c32fd1cb0bc72c45b9a797735 236 SUPERFAMILY SSF53448 8 226 5.34E-24 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS00140 ed8dca4c32fd1cb0bc72c45b9a797735 236 TIGRFAM TIGR04283 glyco_like_mftF: transferase 2, rSAM/selenodomain-associated 12 236 5.7E-64 T 22-04-2016 IPR026461 Transferase 2, rSAM/selenodomain-associated HRM2_RS00140 ed8dca4c32fd1cb0bc72c45b9a797735 236 PANTHER PTHR10859 2 187 8.0E-24 T 22-04-2016 HRM2_RS07765 9f3bc5dc67cd681e20835a1a76cef6e0 600 SUPERFAMILY SSF52540 32 240 3.51E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07765 9f3bc5dc67cd681e20835a1a76cef6e0 600 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS07765 9f3bc5dc67cd681e20835a1a76cef6e0 600 Pfam PF00005 ABC transporter 38 181 2.1E-28 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS07765 9f3bc5dc67cd681e20835a1a76cef6e0 600 Pfam PF00005 ABC transporter 364 507 8.9E-27 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS07765 9f3bc5dc67cd681e20835a1a76cef6e0 600 PANTHER PTHR24220:SF0 325 467 2.6E-126 T 22-04-2016 HRM2_RS07765 9f3bc5dc67cd681e20835a1a76cef6e0 600 PANTHER PTHR24220:SF0 19 245 2.6E-126 T 22-04-2016 HRM2_RS07765 9f3bc5dc67cd681e20835a1a76cef6e0 600 SMART SM00382 47 229 9.5E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS07765 9f3bc5dc67cd681e20835a1a76cef6e0 600 SMART SM00382 372 554 4.0E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS07765 9f3bc5dc67cd681e20835a1a76cef6e0 600 PANTHER PTHR24220 325 467 2.6E-126 T 22-04-2016 HRM2_RS07765 9f3bc5dc67cd681e20835a1a76cef6e0 600 PANTHER PTHR24220 19 245 2.6E-126 T 22-04-2016 HRM2_RS07765 9f3bc5dc67cd681e20835a1a76cef6e0 600 Gene3D G3DSA:3.40.50.300 16 239 2.1E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07765 9f3bc5dc67cd681e20835a1a76cef6e0 600 Gene3D G3DSA:3.40.50.300 338 564 4.7E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07765 9f3bc5dc67cd681e20835a1a76cef6e0 600 SUPERFAMILY SSF52540 337 565 5.98E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09105 bfc968aac4cc462889bbf3fa45b0db9f 244 Hamap MF_00057 3-deoxy-manno-octulosonate cytidylyltransferase [kdsB]. 1 242 37.099 T 22-04-2016 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|UniPathway: UPA00030|UniPathway: UPA00358 HRM2_RS09105 bfc968aac4cc462889bbf3fa45b0db9f 244 SUPERFAMILY SSF53448 1 241 6.76E-58 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS09105 bfc968aac4cc462889bbf3fa45b0db9f 244 PANTHER PTHR21485:SF4 3 241 6.8E-99 T 22-04-2016 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|UniPathway: UPA00030|UniPathway: UPA00358 HRM2_RS09105 bfc968aac4cc462889bbf3fa45b0db9f 244 Gene3D G3DSA:3.90.550.10 2 240 3.0E-71 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS09105 bfc968aac4cc462889bbf3fa45b0db9f 244 PANTHER PTHR21485 3 241 6.8E-99 T 22-04-2016 HRM2_RS09105 bfc968aac4cc462889bbf3fa45b0db9f 244 Pfam PF02348 Cytidylyltransferase 3 216 8.7E-53 T 22-04-2016 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|UniPathway: UPA00030|UniPathway: UPA00358 HRM2_RS09105 bfc968aac4cc462889bbf3fa45b0db9f 244 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 3 234 2.9E-68 T 22-04-2016 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|UniPathway: UPA00030|UniPathway: UPA00358 HRM2_RS18865 695c0630386e2a5b64b7cd8e4be29b9c 136 Pfam PF00072 Response regulator receiver domain 7 115 2.0E-30 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18865 695c0630386e2a5b64b7cd8e4be29b9c 136 Gene3D G3DSA:3.40.50.2300 4 129 3.1E-38 T 22-04-2016 HRM2_RS18865 695c0630386e2a5b64b7cd8e4be29b9c 136 PANTHER PTHR26402 4 131 9.0E-38 T 22-04-2016 HRM2_RS18865 695c0630386e2a5b64b7cd8e4be29b9c 136 SMART SM00448 4 115 6.8E-33 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18865 695c0630386e2a5b64b7cd8e4be29b9c 136 SUPERFAMILY SSF52172 4 128 4.55E-39 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS19595 b096acb94f21bd04f417571e30f6f1d9 113 Gene3D G3DSA:1.25.40.10 19 96 1.3E-10 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS19595 b096acb94f21bd04f417571e30f6f1d9 113 SMART SM00028 56 89 8.0E-4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS19595 b096acb94f21bd04f417571e30f6f1d9 113 Pfam PF13424 Tetratricopeptide repeat 18 87 3.2E-17 T 22-04-2016 HRM2_RS19595 b096acb94f21bd04f417571e30f6f1d9 113 PANTHER PTHR19959 49 97 4.8E-19 T 22-04-2016 HRM2_RS19595 b096acb94f21bd04f417571e30f6f1d9 113 SUPERFAMILY SSF48452 17 100 3.57E-12 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS06545 253b76283bd58b916acc4901025e9c2d 650 Pfam PF04984 Phage tail sheath protein 1 643 3.0E-40 T 22-04-2016 IPR007067 Tail sheath protein HRM2_RS06545 253b76283bd58b916acc4901025e9c2d 650 PANTHER PTHR35861:SF1 461 644 4.9E-56 T 22-04-2016 HRM2_RS06545 253b76283bd58b916acc4901025e9c2d 650 PANTHER PTHR35861 461 644 4.9E-56 T 22-04-2016 HRM2_RS22715 391c7fed0a711390aa82c3ed6c12c8be 364 SUPERFAMILY SSF103025 5 276 3.45E-66 T 22-04-2016 HRM2_RS22715 391c7fed0a711390aa82c3ed6c12c8be 364 Gene3D G3DSA:2.40.30.110 282 355 1.4E-12 T 22-04-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 HRM2_RS22715 391c7fed0a711390aa82c3ed6c12c8be 364 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 265 355 1.0E-13 T 22-04-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 HRM2_RS22715 391c7fed0a711390aa82c3ed6c12c8be 364 PIRSF PIRSF006487 1 364 6.0E-76 T 22-04-2016 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 HRM2_RS22715 391c7fed0a711390aa82c3ed6c12c8be 364 Pfam PF01571 Aminomethyltransferase folate-binding domain 10 258 7.0E-57 T 22-04-2016 IPR006222 Glycine cleavage T-protein-like, N-terminal HRM2_RS22715 391c7fed0a711390aa82c3ed6c12c8be 364 Gene3D G3DSA:3.30.1360.120 144 236 1.3E-31 T 22-04-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 HRM2_RS22715 391c7fed0a711390aa82c3ed6c12c8be 364 Gene3D G3DSA:3.30.1360.120 6 58 1.3E-31 T 22-04-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 HRM2_RS22715 391c7fed0a711390aa82c3ed6c12c8be 364 Gene3D G3DSA:3.30.70.1400 59 127 3.2E-17 T 22-04-2016 HRM2_RS22715 391c7fed0a711390aa82c3ed6c12c8be 364 SUPERFAMILY SSF101790 282 361 3.92E-12 T 22-04-2016 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain HRM2_RS22715 391c7fed0a711390aa82c3ed6c12c8be 364 PANTHER PTHR13847 10 274 2.7E-14 T 22-04-2016 HRM2_RS22715 391c7fed0a711390aa82c3ed6c12c8be 364 PANTHER PTHR13847:SF209 10 274 2.7E-14 T 22-04-2016 HRM2_RS18875 1593b60aef15cc3805348fc90176a2eb 565 PRINTS PR00344 Bacterial sensor protein C-terminal signature 517 535 6.2E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS18875 1593b60aef15cc3805348fc90176a2eb 565 PRINTS PR00344 Bacterial sensor protein C-terminal signature 541 554 6.2E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS18875 1593b60aef15cc3805348fc90176a2eb 565 PRINTS PR00344 Bacterial sensor protein C-terminal signature 504 514 6.2E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS18875 1593b60aef15cc3805348fc90176a2eb 565 PRINTS PR00344 Bacterial sensor protein C-terminal signature 486 500 6.2E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS18875 1593b60aef15cc3805348fc90176a2eb 565 SMART SM00387 447 557 2.0E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS18875 1593b60aef15cc3805348fc90176a2eb 565 Gene3D G3DSA:3.30.450.20 161 272 2.5E-7 T 22-04-2016 HRM2_RS18875 1593b60aef15cc3805348fc90176a2eb 565 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 448 556 6.4E-20 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS18875 1593b60aef15cc3805348fc90176a2eb 565 Pfam PF02743 Cache domain 42 261 1.5E-21 T 22-04-2016 IPR033479 Double Cache domain 1 HRM2_RS18875 1593b60aef15cc3805348fc90176a2eb 565 SUPERFAMILY SSF55874 402 555 5.89E-40 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS18875 1593b60aef15cc3805348fc90176a2eb 565 SUPERFAMILY SSF47384 324 404 9.22E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS18875 1593b60aef15cc3805348fc90176a2eb 565 PANTHER PTHR24423:SF450 158 165 6.7E-60 T 22-04-2016 HRM2_RS18875 1593b60aef15cc3805348fc90176a2eb 565 PANTHER PTHR24423:SF450 311 556 6.7E-60 T 22-04-2016 HRM2_RS18875 1593b60aef15cc3805348fc90176a2eb 565 Gene3D G3DSA:3.30.565.10 406 556 3.1E-42 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS18875 1593b60aef15cc3805348fc90176a2eb 565 Gene3D G3DSA:1.10.287.130 326 401 2.2E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS18875 1593b60aef15cc3805348fc90176a2eb 565 SMART SM00388 327 405 0.0019 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS18875 1593b60aef15cc3805348fc90176a2eb 565 Gene3D G3DSA:3.30.450.20 88 160 3.5E-6 T 22-04-2016 HRM2_RS18875 1593b60aef15cc3805348fc90176a2eb 565 PANTHER PTHR24423 158 165 6.7E-60 T 22-04-2016 HRM2_RS18875 1593b60aef15cc3805348fc90176a2eb 565 PANTHER PTHR24423 311 556 6.7E-60 T 22-04-2016 HRM2_RS17905 21fa8c30ffb16bb31c1266035c447cad 102 SMART SM01403 7 101 1.1E-57 T 22-04-2016 IPR027486 Ribosomal protein S10 domain HRM2_RS17905 21fa8c30ffb16bb31c1266035c447cad 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 22-04-2016 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17905 21fa8c30ffb16bb31c1266035c447cad 102 Gene3D G3DSA:3.30.70.600 4 102 6.5E-45 T 22-04-2016 IPR027486 Ribosomal protein S10 domain HRM2_RS17905 21fa8c30ffb16bb31c1266035c447cad 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 4.1E-37 T 22-04-2016 IPR027486 Ribosomal protein S10 domain HRM2_RS17905 21fa8c30ffb16bb31c1266035c447cad 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 1.8E-20 T 22-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17905 21fa8c30ffb16bb31c1266035c447cad 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 1.8E-20 T 22-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17905 21fa8c30ffb16bb31c1266035c447cad 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 1.8E-20 T 22-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17905 21fa8c30ffb16bb31c1266035c447cad 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 26.878 T 22-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17905 21fa8c30ffb16bb31c1266035c447cad 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 5 101 5.2E-47 T 22-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17905 21fa8c30ffb16bb31c1266035c447cad 102 PANTHER PTHR11700 4 102 1.1E-52 T 22-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 HRM2_RS17905 21fa8c30ffb16bb31c1266035c447cad 102 SUPERFAMILY SSF54999 5 102 1.7E-39 T 22-04-2016 IPR027486 Ribosomal protein S10 domain HRM2_RS01455 2119ddaedd1e07fa6f68a73e8abb17bb 311 SUPERFAMILY SSF52402 5 148 4.52E-17 T 22-04-2016 HRM2_RS01455 2119ddaedd1e07fa6f68a73e8abb17bb 311 SUPERFAMILY SSF52402 162 303 1.42E-16 T 22-04-2016 HRM2_RS01455 2119ddaedd1e07fa6f68a73e8abb17bb 311 Gene3D G3DSA:3.40.50.620 2 156 1.9E-20 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS01455 2119ddaedd1e07fa6f68a73e8abb17bb 311 Gene3D G3DSA:3.40.50.620 163 310 1.5E-19 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS01455 2119ddaedd1e07fa6f68a73e8abb17bb 311 Pfam PF00582 Universal stress protein family 5 148 5.1E-9 T 22-04-2016 IPR006016 UspA GO:0006950 HRM2_RS01455 2119ddaedd1e07fa6f68a73e8abb17bb 311 Pfam PF00582 Universal stress protein family 163 304 1.0E-11 T 22-04-2016 IPR006016 UspA GO:0006950 HRM2_RS23335 177b4838bb7777be6204521c47448187 1740 PANTHER PTHR13710 1706 1715 1.4E-119 T 22-04-2016 HRM2_RS23335 177b4838bb7777be6204521c47448187 1740 PANTHER PTHR13710 293 658 1.4E-119 T 22-04-2016 HRM2_RS23335 177b4838bb7777be6204521c47448187 1740 Gene3D G3DSA:3.40.50.300 1333 1446 1.2E-29 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23335 177b4838bb7777be6204521c47448187 1740 Gene3D G3DSA:3.40.50.300 1531 1602 1.2E-29 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23335 177b4838bb7777be6204521c47448187 1740 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 299 656 8.6E-86 T 22-04-2016 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 HRM2_RS23335 177b4838bb7777be6204521c47448187 1740 Gene3D G3DSA:3.40.50.300 510 670 1.4E-37 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23335 177b4838bb7777be6204521c47448187 1740 Pfam PF00580 UvrD/REP helicase N-terminal domain 1218 1320 1.7E-18 T 22-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 HRM2_RS23335 177b4838bb7777be6204521c47448187 1740 Pfam PF00580 UvrD/REP helicase N-terminal domain 1116 1207 6.7E-19 T 22-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 HRM2_RS23335 177b4838bb7777be6204521c47448187 1740 SUPERFAMILY SSF53098 52 155 8.44E-6 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS23335 177b4838bb7777be6204521c47448187 1740 PANTHER PTHR13710:SF81 1706 1715 1.4E-119 T 22-04-2016 HRM2_RS23335 177b4838bb7777be6204521c47448187 1740 PANTHER PTHR13710:SF81 293 658 1.4E-119 T 22-04-2016 HRM2_RS23335 177b4838bb7777be6204521c47448187 1740 SUPERFAMILY SSF52540 1109 1593 7.63E-82 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23335 177b4838bb7777be6204521c47448187 1740 Gene3D G3DSA:3.40.50.300 295 499 1.8E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23335 177b4838bb7777be6204521c47448187 1740 Pfam PF13361 UvrD-like helicase C-terminal domain 1526 1590 2.3E-13 T 22-04-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 HRM2_RS23335 177b4838bb7777be6204521c47448187 1740 Pfam PF13361 UvrD-like helicase C-terminal domain 1326 1474 1.0E-9 T 22-04-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 HRM2_RS23335 177b4838bb7777be6204521c47448187 1740 Gene3D G3DSA:3.30.420.10 33 134 7.9E-7 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS23335 177b4838bb7777be6204521c47448187 1740 Gene3D G3DSA:3.40.50.300 1107 1332 9.4E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23335 177b4838bb7777be6204521c47448187 1740 Pfam PF00270 DEAD/DEAH box helicase 317 488 6.4E-21 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HRM2_RS23335 177b4838bb7777be6204521c47448187 1740 Pfam PF00271 Helicase conserved C-terminal domain 534 637 6.7E-16 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS23335 177b4838bb7777be6204521c47448187 1740 SMART SM00490 558 639 1.9E-24 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS23335 177b4838bb7777be6204521c47448187 1740 SUPERFAMILY SSF52540 322 651 5.05E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23335 177b4838bb7777be6204521c47448187 1740 SMART SM00487 311 521 7.5E-20 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS23335 177b4838bb7777be6204521c47448187 1740 SMART SM00487 1109 1316 0.056 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS06230 363e1348c985199e69c3f18da0e9e8d2 328 Pfam PF00072 Response regulator receiver domain 203 314 1.3E-24 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS06230 363e1348c985199e69c3f18da0e9e8d2 328 Gene3D G3DSA:1.10.287.130 105 173 9.2E-5 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS06230 363e1348c985199e69c3f18da0e9e8d2 328 PANTHER PTHR24423:SF379 197 319 7.7E-35 T 22-04-2016 HRM2_RS06230 363e1348c985199e69c3f18da0e9e8d2 328 SUPERFAMILY SSF47384 101 173 2.35E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS06230 363e1348c985199e69c3f18da0e9e8d2 328 SMART SM00448 201 314 2.9E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS06230 363e1348c985199e69c3f18da0e9e8d2 328 Gene3D G3DSA:3.40.50.2300 200 322 2.1E-33 T 22-04-2016 HRM2_RS06230 363e1348c985199e69c3f18da0e9e8d2 328 SUPERFAMILY SSF52172 201 322 3.27E-34 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS06230 363e1348c985199e69c3f18da0e9e8d2 328 PANTHER PTHR24423 197 319 7.7E-35 T 22-04-2016 HRM2_RS06230 363e1348c985199e69c3f18da0e9e8d2 328 SMART SM00388 112 178 0.0088 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS18050 32720958647c84c037cb7b15ac7f2647 230 Gene3D G3DSA:3.40.140.10 94 218 9.9E-41 T 22-04-2016 HRM2_RS18050 32720958647c84c037cb7b15ac7f2647 230 Gene3D G3DSA:1.10.150.20 41 71 7.5E-9 T 22-04-2016 HRM2_RS18050 32720958647c84c037cb7b15ac7f2647 230 SUPERFAMILY SSF102712 101 184 3.27E-5 T 22-04-2016 HRM2_RS18050 32720958647c84c037cb7b15ac7f2647 230 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 167 172 - T 22-04-2016 IPR020891 Uncharacterised protein family UPF0758, conserved site HRM2_RS18050 32720958647c84c037cb7b15ac7f2647 230 Pfam PF04002 RadC-like JAB domain 98 216 4.1E-38 T 22-04-2016 IPR025657 RadC-like JAB domain HRM2_RS18050 32720958647c84c037cb7b15ac7f2647 230 PANTHER PTHR30471:SF3 1 218 2.9E-65 T 22-04-2016 HRM2_RS18050 32720958647c84c037cb7b15ac7f2647 230 PANTHER PTHR30471 1 218 2.9E-65 T 22-04-2016 HRM2_RS18050 32720958647c84c037cb7b15ac7f2647 230 SUPERFAMILY SSF47781 28 76 1.43E-8 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 HRM2_RS18050 32720958647c84c037cb7b15ac7f2647 230 TIGRFAM TIGR00608 radc: DNA repair protein RadC 6 218 1.9E-58 T 22-04-2016 IPR001405 RadC protein HRM2_RS11660 bcdd535a436514227378f96cb175656f 188 SUPERFAMILY SSF50249 132 188 5.48E-14 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS11660 bcdd535a436514227378f96cb175656f 188 Pfam PF01132 Elongation factor P (EF-P) OB domain 70 122 1.5E-14 T 22-04-2016 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 UniPathway: UPA00345 HRM2_RS11660 bcdd535a436514227378f96cb175656f 188 Gene3D G3DSA:2.40.50.140 67 130 5.4E-17 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS11660 bcdd535a436514227378f96cb175656f 188 PANTHER PTHR30053 1 188 3.6E-70 T 22-04-2016 HRM2_RS11660 bcdd535a436514227378f96cb175656f 188 PANTHER PTHR30053:SF5 1 188 3.6E-70 T 22-04-2016 HRM2_RS11660 bcdd535a436514227378f96cb175656f 188 ProSitePatterns PS01275 Elongation factor P signature. 153 172 - T 22-04-2016 IPR013852 Translation elongation factor P/YeiP, conserved site UniPathway: UPA00345 HRM2_RS11660 bcdd535a436514227378f96cb175656f 188 SMART SM01185 69 124 5.6E-17 T 22-04-2016 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 UniPathway: UPA00345 HRM2_RS11660 bcdd535a436514227378f96cb175656f 188 PIRSF PIRSF005901 1 188 1.2E-57 T 22-04-2016 IPR020599 Translation elongation factor P/YeiP UniPathway: UPA00345 HRM2_RS11660 bcdd535a436514227378f96cb175656f 188 SMART SM00841 132 187 4.5E-23 T 22-04-2016 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 UniPathway: UPA00345 HRM2_RS11660 bcdd535a436514227378f96cb175656f 188 Gene3D G3DSA:2.30.30.30 1 62 8.3E-12 T 22-04-2016 IPR014722 Ribosomal protein L2 domain 2 HRM2_RS11660 bcdd535a436514227378f96cb175656f 188 Pfam PF09285 Elongation factor P, C-terminal 134 187 1.2E-18 T 22-04-2016 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 UniPathway: UPA00345 HRM2_RS11660 bcdd535a436514227378f96cb175656f 188 Gene3D G3DSA:2.40.50.140 133 188 1.5E-20 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS11660 bcdd535a436514227378f96cb175656f 188 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 4 62 4.7E-12 T 22-04-2016 IPR013185 Translation elongation factor, KOW-like UniPathway: UPA00345 HRM2_RS11660 bcdd535a436514227378f96cb175656f 188 SUPERFAMILY SSF50249 68 129 2.83E-12 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS11660 bcdd535a436514227378f96cb175656f 188 SUPERFAMILY SSF50104 1 63 1.62E-8 T 22-04-2016 IPR008991 Translation protein SH3-like domain HRM2_RS07465 1df4b936d2763f242d466b77f3d2a4d8 108 SUPERFAMILY SSF46785 8 106 3.04E-35 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS07465 1df4b936d2763f242d466b77f3d2a4d8 108 Pfam PF01638 HxlR-like helix-turn-helix 20 105 9.4E-37 T 22-04-2016 IPR002577 Helix-turn-helix, HxlR type HRM2_RS07465 1df4b936d2763f242d466b77f3d2a4d8 108 PANTHER PTHR33204 11 104 1.3E-52 T 22-04-2016 HRM2_RS07465 1df4b936d2763f242d466b77f3d2a4d8 108 Gene3D G3DSA:1.10.10.10 5 106 8.9E-45 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS07465 1df4b936d2763f242d466b77f3d2a4d8 108 PANTHER PTHR33204:SF5 11 104 1.3E-52 T 22-04-2016 HRM2_RS00610 ced8d1e8fa025e1b20c6861555bf09f3 459 SMART SM00382 164 308 1.5E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS00610 ced8d1e8fa025e1b20c6861555bf09f3 459 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 231 246 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS00610 ced8d1e8fa025e1b20c6861555bf09f3 459 Gene3D G3DSA:3.40.50.2300 5 129 1.9E-32 T 22-04-2016 HRM2_RS00610 ced8d1e8fa025e1b20c6861555bf09f3 459 SUPERFAMILY SSF52172 5 188 1.71E-39 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS00610 ced8d1e8fa025e1b20c6861555bf09f3 459 Pfam PF00072 Response regulator receiver domain 7 114 5.7E-25 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS00610 ced8d1e8fa025e1b20c6861555bf09f3 459 PANTHER PTHR32071 3 453 2.5E-172 T 22-04-2016 HRM2_RS00610 ced8d1e8fa025e1b20c6861555bf09f3 459 Gene3D G3DSA:1.10.10.60 414 457 4.7E-6 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS00610 ced8d1e8fa025e1b20c6861555bf09f3 459 Pfam PF00158 Sigma-54 interaction domain 144 311 2.9E-65 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS00610 ced8d1e8fa025e1b20c6861555bf09f3 459 SMART SM00448 5 115 4.1E-32 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS00610 ced8d1e8fa025e1b20c6861555bf09f3 459 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 168 181 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS00610 ced8d1e8fa025e1b20c6861555bf09f3 459 Gene3D G3DSA:1.10.8.60 318 387 5.5E-23 T 22-04-2016 HRM2_RS00610 ced8d1e8fa025e1b20c6861555bf09f3 459 Gene3D G3DSA:3.40.50.300 143 316 1.9E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00610 ced8d1e8fa025e1b20c6861555bf09f3 459 SUPERFAMILY SSF46689 358 457 2.91E-8 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS00610 ced8d1e8fa025e1b20c6861555bf09f3 459 SUPERFAMILY SSF52540 144 386 1.59E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22620 cca61396aa0e4c9f77e546ab2ae25658 437 SMART SM00729 144 362 1.3E-41 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS22620 cca61396aa0e4c9f77e546ab2ae25658 437 SUPERFAMILY SSF102114 134 366 5.49E-51 T 22-04-2016 HRM2_RS22620 cca61396aa0e4c9f77e546ab2ae25658 437 Pfam PF00919 Uncharacterized protein family UPF0004 4 98 7.9E-23 T 22-04-2016 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 HRM2_RS22620 cca61396aa0e4c9f77e546ab2ae25658 437 PANTHER PTHR11918 5 413 5.6E-108 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein HRM2_RS22620 cca61396aa0e4c9f77e546ab2ae25658 437 Gene3D G3DSA:3.80.30.20 142 370 4.1E-65 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe HRM2_RS22620 cca61396aa0e4c9f77e546ab2ae25658 437 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 148 168 - T 22-04-2016 IPR020612 Methylthiotransferase, conserved site GO:0051539 HRM2_RS22620 cca61396aa0e4c9f77e546ab2ae25658 437 Pfam PF04055 Radical SAM superfamily 150 319 4.4E-23 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS22620 cca61396aa0e4c9f77e546ab2ae25658 437 PANTHER PTHR11918:SF45 5 413 5.6E-108 T 22-04-2016 HRM2_RS22620 cca61396aa0e4c9f77e546ab2ae25658 437 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 4 426 8.7E-112 T 22-04-2016 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 HRM2_RS22620 cca61396aa0e4c9f77e546ab2ae25658 437 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 6 411 2.9E-120 T 22-04-2016 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 HRM2_RS14145 1bf1cc4ccadf0eedffe7b710bc54dc8a 628 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 122 495 2.7E-57 T 22-04-2016 IPR000914 Solute-binding protein family 5 domain HRM2_RS14145 1bf1cc4ccadf0eedffe7b710bc54dc8a 628 Gene3D G3DSA:3.40.190.10 199 349 1.3E-25 T 22-04-2016 HRM2_RS14145 1bf1cc4ccadf0eedffe7b710bc54dc8a 628 Gene3D G3DSA:3.90.76.10 112 198 1.3E-19 T 22-04-2016 HRM2_RS14145 1bf1cc4ccadf0eedffe7b710bc54dc8a 628 SUPERFAMILY SSF53850 74 569 1.18E-95 T 22-04-2016 HRM2_RS14145 1bf1cc4ccadf0eedffe7b710bc54dc8a 628 Gene3D G3DSA:3.10.105.10 350 553 7.3E-44 T 22-04-2016 HRM2_RS14145 1bf1cc4ccadf0eedffe7b710bc54dc8a 628 PANTHER PTHR30290 68 606 1.4E-71 T 22-04-2016 HRM2_RS10965 14a4b62bad1b48ad32b2d3932aa94a58 449 Gene3D G3DSA:3.40.50.450 45 302 1.7E-71 T 22-04-2016 HRM2_RS10965 14a4b62bad1b48ad32b2d3932aa94a58 449 SUPERFAMILY SSF53784 37 438 7.46E-117 T 22-04-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS10965 14a4b62bad1b48ad32b2d3932aa94a58 449 Hamap MF_01981 ATP-dependent 6-phosphofructokinase [pfkA]. 6 439 49.581 T 22-04-2016 IPR012004 Pyrophosphate-dependent phosphofructokinase TP0108-type GO:0003872|GO:0005524|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 HRM2_RS10965 14a4b62bad1b48ad32b2d3932aa94a58 449 Pfam PF00365 Phosphofructokinase 81 386 4.2E-61 T 22-04-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS10965 14a4b62bad1b48ad32b2d3932aa94a58 449 PANTHER PTHR13697 32 440 5.7E-153 T 22-04-2016 HRM2_RS10965 14a4b62bad1b48ad32b2d3932aa94a58 449 PANTHER PTHR13697:SF27 32 440 5.7E-153 T 22-04-2016 HRM2_RS10965 14a4b62bad1b48ad32b2d3932aa94a58 449 PIRSF PIRSF000534 1 443 1.3E-166 T 22-04-2016 IPR012004 Pyrophosphate-dependent phosphofructokinase TP0108-type GO:0003872|GO:0005524|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 HRM2_RS10965 14a4b62bad1b48ad32b2d3932aa94a58 449 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 83 102 4.7E-22 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS10965 14a4b62bad1b48ad32b2d3932aa94a58 449 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 221 239 4.7E-22 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS10965 14a4b62bad1b48ad32b2d3932aa94a58 449 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 299 311 4.7E-22 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS10965 14a4b62bad1b48ad32b2d3932aa94a58 449 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 170 186 4.7E-22 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS10965 14a4b62bad1b48ad32b2d3932aa94a58 449 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 203 220 4.7E-22 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS10965 14a4b62bad1b48ad32b2d3932aa94a58 449 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 242 258 4.7E-22 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS11930 a19dac5fe947407fa847458820bc3c9e 287 PANTHER PTHR23264 14 287 1.6E-122 T 22-04-2016 IPR019591 Mrp/NBP35 ATP-binding protein HRM2_RS11930 a19dac5fe947407fa847458820bc3c9e 287 Gene3D G3DSA:3.40.50.300 26 282 3.6E-96 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11930 a19dac5fe947407fa847458820bc3c9e 287 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 38 283 2.6E-94 T 22-04-2016 IPR019591 Mrp/NBP35 ATP-binding protein HRM2_RS11930 a19dac5fe947407fa847458820bc3c9e 287 ProSitePatterns PS01215 Mrp family signature. 147 163 - T 22-04-2016 IPR000808 Mrp, conserved site GO:0005524 HRM2_RS11930 a19dac5fe947407fa847458820bc3c9e 287 Hamap MF_02040 Iron-sulfur cluster carrier protein. 34 284 34.284 T 22-04-2016 IPR019591 Mrp/NBP35 ATP-binding protein HRM2_RS11930 a19dac5fe947407fa847458820bc3c9e 287 SUPERFAMILY SSF52540 27 265 7.56E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22570 89890c50f20bb7dcd89c084b477b15e3 161 Gene3D G3DSA:2.40.320.10 1 152 5.3E-52 T 22-04-2016 IPR023577 CYTH domain HRM2_RS22570 89890c50f20bb7dcd89c084b477b15e3 161 Pfam PF01928 CYTH domain 2 144 1.1E-11 T 22-04-2016 IPR023577 CYTH domain HRM2_RS22570 89890c50f20bb7dcd89c084b477b15e3 161 SMART SM01118 2 149 1.4E-18 T 22-04-2016 IPR023577 CYTH domain HRM2_RS22570 89890c50f20bb7dcd89c084b477b15e3 161 PIRSF PIRSF016487 1 158 1.9E-59 T 22-04-2016 IPR012042 Inorganic triphosphatase NeuTTM/CthTTM-like HRM2_RS22570 89890c50f20bb7dcd89c084b477b15e3 161 SUPERFAMILY SSF55154 1 149 1.11E-40 T 22-04-2016 IPR033469 CYTH-like domain HRM2_RS22570 89890c50f20bb7dcd89c084b477b15e3 161 PANTHER PTHR40114 2 158 4.8E-43 T 22-04-2016 HRM2_RS09490 d519144b8e1c674973de81185067b141 98 Gene3D G3DSA:1.10.10.10 14 60 1.6E-6 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS09490 d519144b8e1c674973de81185067b141 98 Pfam PF12728 Helix-turn-helix domain 16 61 1.9E-6 T 22-04-2016 HRM2_RS09490 d519144b8e1c674973de81185067b141 98 SUPERFAMILY SSF46955 14 63 1.28E-8 T 22-04-2016 IPR009061 Putative DNA-binding domain HRM2_RS23000 383f36dc3e589f35715bd8577343e49f 250 PANTHER PTHR34698 13 240 5.8E-85 T 22-04-2016 HRM2_RS23000 383f36dc3e589f35715bd8577343e49f 250 Gene3D G3DSA:3.30.1360.40 19 95 1.8E-19 T 22-04-2016 IPR024946 Arginine repressor C-terminal-like domain HRM2_RS23000 383f36dc3e589f35715bd8577343e49f 250 SMART SM00796 17 218 2.0E-92 T 22-04-2016 IPR003833 Carboxyltransferase domain, subdomain C and D HRM2_RS23000 383f36dc3e589f35715bd8577343e49f 250 PANTHER PTHR34698:SF2 13 240 5.8E-85 T 22-04-2016 HRM2_RS23000 383f36dc3e589f35715bd8577343e49f 250 SUPERFAMILY SSF160467 19 109 7.72E-18 T 22-04-2016 HRM2_RS23000 383f36dc3e589f35715bd8577343e49f 250 Gene3D G3DSA:2.40.100.10 105 239 1.9E-50 T 22-04-2016 IPR029000 Cyclophilin-like domain HRM2_RS23000 383f36dc3e589f35715bd8577343e49f 250 Pfam PF02682 Allophanate hydrolase subunit 1 19 218 3.5E-72 T 22-04-2016 IPR003833 Carboxyltransferase domain, subdomain C and D HRM2_RS23000 383f36dc3e589f35715bd8577343e49f 250 SUPERFAMILY SSF50891 105 234 2.65E-46 T 22-04-2016 IPR029000 Cyclophilin-like domain HRM2_RS23000 383f36dc3e589f35715bd8577343e49f 250 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 23 226 1.3E-61 T 22-04-2016 IPR010016 KipI family HRM2_RS04315 60e77106422e6d5aafa28301947fc806 275 Gene3D G3DSA:2.10.240.10 218 248 4.3E-4 T 22-04-2016 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain UniPathway: UPA00070 HRM2_RS04315 60e77106422e6d5aafa28301947fc806 275 PANTHER PTHR11938 55 264 6.6E-48 T 22-04-2016 HRM2_RS04315 60e77106422e6d5aafa28301947fc806 275 SUPERFAMILY SSF52343 89 248 3.4E-34 T 22-04-2016 HRM2_RS04315 60e77106422e6d5aafa28301947fc806 275 Pfam PF00175 Oxidoreductase NAD-binding domain 105 197 1.2E-5 T 22-04-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 HRM2_RS04315 60e77106422e6d5aafa28301947fc806 275 Gene3D G3DSA:3.40.50.80 95 210 7.4E-37 T 22-04-2016 HRM2_RS04315 60e77106422e6d5aafa28301947fc806 275 Gene3D G3DSA:2.40.30.10 1 92 1.2E-21 T 22-04-2016 HRM2_RS04315 60e77106422e6d5aafa28301947fc806 275 PANTHER PTHR11938:SF47 55 264 6.6E-48 T 22-04-2016 HRM2_RS04315 60e77106422e6d5aafa28301947fc806 275 PIRSF PIRSF006816 1 254 4.0E-65 T 22-04-2016 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 UniPathway: UPA00070 HRM2_RS04315 60e77106422e6d5aafa28301947fc806 275 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 213 249 1.1E-12 T 22-04-2016 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain UniPathway: UPA00070 HRM2_RS04315 60e77106422e6d5aafa28301947fc806 275 SUPERFAMILY SSF63380 2 92 6.81E-15 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 HRM2_RS13400 4bb22a32100ab1fa7d6efc35a69325c6 207 PANTHER PTHR13016 61 207 4.9E-27 T 22-04-2016 IPR023473 AMMECR1 HRM2_RS13400 4bb22a32100ab1fa7d6efc35a69325c6 207 Gene3D G3DSA:3.30.700.20 3 145 4.3E-35 T 22-04-2016 IPR027485 AMMECR1, N-terminal HRM2_RS13400 4bb22a32100ab1fa7d6efc35a69325c6 207 SUPERFAMILY SSF143447 49 207 3.4E-48 T 22-04-2016 IPR002733 AMMECR1 domain HRM2_RS13400 4bb22a32100ab1fa7d6efc35a69325c6 207 Gene3D G3DSA:3.30.1490.150 146 202 1.3E-20 T 22-04-2016 HRM2_RS13400 4bb22a32100ab1fa7d6efc35a69325c6 207 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 59 206 1.5E-33 T 22-04-2016 IPR023473 AMMECR1 HRM2_RS13400 4bb22a32100ab1fa7d6efc35a69325c6 207 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 57 206 4.8E-54 T 22-04-2016 IPR027623 AmmeMemoRadiSam system protein A HRM2_RS13400 4bb22a32100ab1fa7d6efc35a69325c6 207 Pfam PF01871 AMMECR1 59 206 3.4E-41 T 22-04-2016 IPR002733 AMMECR1 domain HRM2_RS11940 00441d396f50ac09dd11c52fc47302b5 613 SUPERFAMILY SSF48452 421 590 3.03E-30 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS11940 00441d396f50ac09dd11c52fc47302b5 613 Pfam PF13181 Tetratricopeptide repeat 566 587 0.14 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11940 00441d396f50ac09dd11c52fc47302b5 613 Pfam PF13181 Tetratricopeptide repeat 533 557 0.064 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11940 00441d396f50ac09dd11c52fc47302b5 613 SUPERFAMILY SSF48452 317 435 2.31E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS11940 00441d396f50ac09dd11c52fc47302b5 613 SMART SM00028 183 216 49.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11940 00441d396f50ac09dd11c52fc47302b5 613 SMART SM00028 561 594 7.9 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11940 00441d396f50ac09dd11c52fc47302b5 613 SMART SM00028 149 182 0.45 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11940 00441d396f50ac09dd11c52fc47302b5 613 SMART SM00028 492 526 66.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11940 00441d396f50ac09dd11c52fc47302b5 613 SMART SM00028 424 457 81.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11940 00441d396f50ac09dd11c52fc47302b5 613 SMART SM00028 115 148 94.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11940 00441d396f50ac09dd11c52fc47302b5 613 SMART SM00028 81 114 0.66 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11940 00441d396f50ac09dd11c52fc47302b5 613 SMART SM00028 527 560 50.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11940 00441d396f50ac09dd11c52fc47302b5 613 SMART SM00028 217 250 8.8 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11940 00441d396f50ac09dd11c52fc47302b5 613 SMART SM00028 458 491 0.059 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS11940 00441d396f50ac09dd11c52fc47302b5 613 Pfam PF13431 Tetratricopeptide repeat 482 507 2.5E-6 T 22-04-2016 HRM2_RS11940 00441d396f50ac09dd11c52fc47302b5 613 PANTHER PTHR23083 400 587 6.5E-62 T 22-04-2016 HRM2_RS11940 00441d396f50ac09dd11c52fc47302b5 613 PANTHER PTHR23083 82 260 6.5E-62 T 22-04-2016 HRM2_RS11940 00441d396f50ac09dd11c52fc47302b5 613 Gene3D G3DSA:1.25.40.10 81 311 5.7E-39 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS11940 00441d396f50ac09dd11c52fc47302b5 613 Gene3D G3DSA:1.25.40.10 331 587 1.9E-44 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS11940 00441d396f50ac09dd11c52fc47302b5 613 Pfam PF13429 Tetratricopeptide repeat 74 206 2.3E-6 T 22-04-2016 HRM2_RS11940 00441d396f50ac09dd11c52fc47302b5 613 SUPERFAMILY SSF48452 83 312 2.28E-29 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS02535 a33e52996d11c53b978199c2ad6be20c 306 Gene3D G3DSA:1.10.3720.10 7 295 6.8E-46 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS02535 a33e52996d11c53b978199c2ad6be20c 306 PANTHER PTHR32243 163 305 3.3E-96 T 22-04-2016 HRM2_RS02535 a33e52996d11c53b978199c2ad6be20c 306 PANTHER PTHR32243 1 136 3.3E-96 T 22-04-2016 HRM2_RS02535 a33e52996d11c53b978199c2ad6be20c 306 SUPERFAMILY SSF161098 5 302 6.67E-51 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS02535 a33e52996d11c53b978199c2ad6be20c 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 301 1.2E-11 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS02535 a33e52996d11c53b978199c2ad6be20c 306 PANTHER PTHR32243:SF31 163 305 3.3E-96 T 22-04-2016 IPR030165 sn-glycerol-3-phosphate transport system permease protein UgpE GO:0001407|GO:0005887|GO:0015794|GO:0055052 HRM2_RS02535 a33e52996d11c53b978199c2ad6be20c 306 PANTHER PTHR32243:SF31 1 136 3.3E-96 T 22-04-2016 IPR030165 sn-glycerol-3-phosphate transport system permease protein UgpE GO:0001407|GO:0005887|GO:0015794|GO:0055052 HRM2_RS23350 3d68f0319bdea2958ee599208e9328f0 588 Pfam PF00501 AMP-binding enzyme 65 474 2.1E-80 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS23350 3d68f0319bdea2958ee599208e9328f0 588 Gene3D G3DSA:2.30.38.10 387 467 9.3E-19 T 22-04-2016 HRM2_RS23350 3d68f0319bdea2958ee599208e9328f0 588 Gene3D G3DSA:3.40.50.980 225 386 3.5E-26 T 22-04-2016 HRM2_RS23350 3d68f0319bdea2958ee599208e9328f0 588 Gene3D G3DSA:3.30.300.30 469 570 2.0E-24 T 22-04-2016 HRM2_RS23350 3d68f0319bdea2958ee599208e9328f0 588 Gene3D G3DSA:3.40.50.980 51 224 6.7E-28 T 22-04-2016 HRM2_RS23350 3d68f0319bdea2958ee599208e9328f0 588 ProSitePatterns PS00455 Putative AMP-binding domain signature. 219 230 - T 22-04-2016 IPR020845 AMP-binding, conserved site HRM2_RS23350 3d68f0319bdea2958ee599208e9328f0 588 Pfam PF13193 AMP-binding enzyme C-terminal domain 483 561 2.3E-21 T 22-04-2016 IPR025110 AMP-binding enzyme C-terminal domain HRM2_RS23350 3d68f0319bdea2958ee599208e9328f0 588 SUPERFAMILY SSF56801 43 575 1.1E-145 T 22-04-2016 HRM2_RS23350 3d68f0319bdea2958ee599208e9328f0 588 PANTHER PTHR24095 47 583 3.0E-177 T 22-04-2016 HRM2_RS14640 2b6d808f879fd728791836550dba6715 303 SUPERFAMILY SSF53850 29 302 5.07E-62 T 22-04-2016 HRM2_RS14640 2b6d808f879fd728791836550dba6715 303 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 28 297 8.1E-60 T 22-04-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 HRM2_RS14640 2b6d808f879fd728791836550dba6715 303 PANTHER PTHR30177:SF9 19 302 2.4E-85 T 22-04-2016 HRM2_RS14640 2b6d808f879fd728791836550dba6715 303 Gene3D G3DSA:3.40.190.120 133 239 6.9E-32 T 22-04-2016 HRM2_RS14640 2b6d808f879fd728791836550dba6715 303 PANTHER PTHR30177 19 302 2.4E-85 T 22-04-2016 HRM2_RS14640 2b6d808f879fd728791836550dba6715 303 Gene3D G3DSA:3.40.190.10 246 303 9.6E-52 T 22-04-2016 HRM2_RS14640 2b6d808f879fd728791836550dba6715 303 Gene3D G3DSA:3.40.190.10 26 132 9.6E-52 T 22-04-2016 HRM2_RS00335 d5564a64efa0acf5b24d30fc70efda70 236 SUPERFAMILY SSF52540 6 229 4.2E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00335 d5564a64efa0acf5b24d30fc70efda70 236 SMART SM00382 34 231 7.7E-14 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS00335 d5564a64efa0acf5b24d30fc70efda70 236 Gene3D G3DSA:3.40.50.300 6 228 1.2E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00335 d5564a64efa0acf5b24d30fc70efda70 236 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS00335 d5564a64efa0acf5b24d30fc70efda70 236 Pfam PF00005 ABC transporter 25 176 1.4E-30 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS00335 d5564a64efa0acf5b24d30fc70efda70 236 PANTHER PTHR24220 7 228 2.6E-77 T 22-04-2016 HRM2_RS24050 81ac26f371fd455ee1ac4543e32e0e6d 489 Gene3D G3DSA:3.40.50.720 190 438 3.3E-53 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS24050 81ac26f371fd455ee1ac4543e32e0e6d 489 PANTHER PTHR24320 149 471 2.3E-78 T 22-04-2016 HRM2_RS24050 81ac26f371fd455ee1ac4543e32e0e6d 489 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 141 5.5E-13 T 22-04-2016 IPR019587 Polyketide cyclase/dehydrase HRM2_RS24050 81ac26f371fd455ee1ac4543e32e0e6d 489 SUPERFAMILY SSF55961 1 141 7.13E-19 T 22-04-2016 HRM2_RS24050 81ac26f371fd455ee1ac4543e32e0e6d 489 Gene3D G3DSA:3.30.530.20 4 118 1.9E-10 T 22-04-2016 IPR023393 START-like domain HRM2_RS24050 81ac26f371fd455ee1ac4543e32e0e6d 489 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 407 427 4.0E-18 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS24050 81ac26f371fd455ee1ac4543e32e0e6d 489 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 275 286 4.0E-18 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS24050 81ac26f371fd455ee1ac4543e32e0e6d 489 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 216 4.0E-18 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS24050 81ac26f371fd455ee1ac4543e32e0e6d 489 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 379 396 4.0E-18 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS24050 81ac26f371fd455ee1ac4543e32e0e6d 489 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 358 377 4.0E-18 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS24050 81ac26f371fd455ee1ac4543e32e0e6d 489 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 319 335 4.0E-18 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS24050 81ac26f371fd455ee1ac4543e32e0e6d 489 SUPERFAMILY SSF51735 197 446 2.01E-52 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS24050 81ac26f371fd455ee1ac4543e32e0e6d 489 PANTHER PTHR24320:SF70 149 471 2.3E-78 T 22-04-2016 HRM2_RS24050 81ac26f371fd455ee1ac4543e32e0e6d 489 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 325 333 2.5E-6 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS24050 81ac26f371fd455ee1ac4543e32e0e6d 489 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 275 286 2.5E-6 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS24050 81ac26f371fd455ee1ac4543e32e0e6d 489 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 358 377 2.5E-6 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS24050 81ac26f371fd455ee1ac4543e32e0e6d 489 Pfam PF00106 short chain dehydrogenase 198 395 3.9E-29 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS11495 7ad1bd58bc41a1b9264e589c570539f1 155 SUPERFAMILY SSF47240 3 151 6.71E-20 T 22-04-2016 IPR009078 Ferritin-like superfamily HRM2_RS11495 7ad1bd58bc41a1b9264e589c570539f1 155 Pfam PF02915 Rubrerythrin 6 151 4.7E-13 T 22-04-2016 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 HRM2_RS11495 7ad1bd58bc41a1b9264e589c570539f1 155 Gene3D G3DSA:1.20.1260.10 1 151 1.7E-30 T 22-04-2016 IPR012347 Ferritin-related HRM2_RS10500 123bde4dca1856985fe2ae2f38771d01 615 SUPERFAMILY SSF100950 9 223 1.61E-25 T 22-04-2016 HRM2_RS10500 123bde4dca1856985fe2ae2f38771d01 615 PANTHER PTHR21432:SF18 11 438 5.7E-101 T 22-04-2016 HRM2_RS10500 123bde4dca1856985fe2ae2f38771d01 615 SUPERFAMILY SSF100950 191 437 3.51E-37 T 22-04-2016 HRM2_RS10500 123bde4dca1856985fe2ae2f38771d01 615 Gene3D G3DSA:3.40.630.30 463 599 8.5E-11 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS10500 123bde4dca1856985fe2ae2f38771d01 615 PANTHER PTHR21432 11 438 5.7E-101 T 22-04-2016 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 HRM2_RS10500 123bde4dca1856985fe2ae2f38771d01 615 Gene3D G3DSA:3.40.1080.10 11 186 3.3E-49 T 22-04-2016 HRM2_RS10500 123bde4dca1856985fe2ae2f38771d01 615 Gene3D G3DSA:3.30.750.70 192 291 1.4E-22 T 22-04-2016 HRM2_RS10500 123bde4dca1856985fe2ae2f38771d01 615 SUPERFAMILY SSF55729 463 600 1.92E-14 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS10500 123bde4dca1856985fe2ae2f38771d01 615 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 16 187 3.2E-14 T 22-04-2016 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 HRM2_RS10500 123bde4dca1856985fe2ae2f38771d01 615 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 275 427 7.9E-40 T 22-04-2016 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain HRM2_RS01645 e5308bcb2a6e8ce73172a460b521e45b 274 Pfam PF02634 FdhD/NarQ family 32 270 1.2E-61 T 22-04-2016 IPR003786 Protein FdhD GO:0016783 HRM2_RS01645 e5308bcb2a6e8ce73172a460b521e45b 274 PANTHER PTHR30592 30 270 3.3E-58 T 22-04-2016 HRM2_RS01645 e5308bcb2a6e8ce73172a460b521e45b 274 Gene3D G3DSA:3.10.20.10 34 121 4.7E-20 T 22-04-2016 HRM2_RS01645 e5308bcb2a6e8ce73172a460b521e45b 274 Gene3D G3DSA:3.40.140.10 134 270 1.1E-36 T 22-04-2016 HRM2_RS01645 e5308bcb2a6e8ce73172a460b521e45b 274 PIRSF PIRSF015626 11 273 8.1E-57 T 22-04-2016 IPR003786 Protein FdhD GO:0016783 HRM2_RS01645 e5308bcb2a6e8ce73172a460b521e45b 274 SUPERFAMILY SSF53927 13 270 9.93E-58 T 22-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 HRM2_RS01645 e5308bcb2a6e8ce73172a460b521e45b 274 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 29 270 1.5E-42 T 22-04-2016 IPR003786 Protein FdhD GO:0016783 HRM2_RS01645 e5308bcb2a6e8ce73172a460b521e45b 274 PANTHER PTHR30592:SF1 30 270 3.3E-58 T 22-04-2016 HRM2_RS10150 2c88d8a5662e758c59c41a9de110cc99 472 PANTHER PTHR23135 7 472 2.8E-117 T 22-04-2016 HRM2_RS10150 2c88d8a5662e758c59c41a9de110cc99 472 Gene3D G3DSA:3.40.50.720 9 101 8.4E-33 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS10150 2c88d8a5662e758c59c41a9de110cc99 472 SUPERFAMILY SSF53623 109 323 1.96E-55 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HRM2_RS10150 2c88d8a5662e758c59c41a9de110cc99 472 Gene3D G3DSA:3.40.1190.10 106 326 2.2E-73 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HRM2_RS10150 2c88d8a5662e758c59c41a9de110cc99 472 SUPERFAMILY SSF53244 324 472 1.43E-36 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HRM2_RS10150 2c88d8a5662e758c59c41a9de110cc99 472 Pfam PF02875 Mur ligase family, glutamate ligase domain 325 399 4.2E-12 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HRM2_RS10150 2c88d8a5662e758c59c41a9de110cc99 472 Gene3D G3DSA:3.90.190.20 327 472 4.0E-37 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HRM2_RS10150 2c88d8a5662e758c59c41a9de110cc99 472 Pfam PF01225 Mur ligase family, catalytic domain 14 112 2.6E-17 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 HRM2_RS10150 2c88d8a5662e758c59c41a9de110cc99 472 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 14 468 9.2E-101 T 22-04-2016 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS10150 2c88d8a5662e758c59c41a9de110cc99 472 SUPERFAMILY SSF51984 13 100 3.01E-22 T 22-04-2016 HRM2_RS10150 2c88d8a5662e758c59c41a9de110cc99 472 Pfam PF08245 Mur ligase middle domain 120 305 1.4E-23 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HRM2_RS10150 2c88d8a5662e758c59c41a9de110cc99 472 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 14 472 4.7E-124 T 22-04-2016 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 UniPathway: UPA00544 HRM2_RS10150 2c88d8a5662e758c59c41a9de110cc99 472 PANTHER PTHR23135:SF17 7 472 2.8E-117 T 22-04-2016 HRM2_RS14550 bb4d49b731f18d4a0e53b648131df6b8 359 SUPERFAMILY SSF53187 36 318 1.26E-60 T 22-04-2016 HRM2_RS14550 bb4d49b731f18d4a0e53b648131df6b8 359 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 52 317 4.7E-51 T 22-04-2016 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 HRM2_RS14550 bb4d49b731f18d4a0e53b648131df6b8 359 PIRSF PIRSF039012 3 325 4.7E-91 T 22-04-2016 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 HRM2_RS14550 bb4d49b731f18d4a0e53b648131df6b8 359 PANTHER PTHR37326 6 341 3.7E-94 T 22-04-2016 HRM2_RS14550 bb4d49b731f18d4a0e53b648131df6b8 359 PANTHER PTHR37326:SF1 6 341 3.7E-94 T 22-04-2016 HRM2_RS14550 bb4d49b731f18d4a0e53b648131df6b8 359 Gene3D G3DSA:3.40.630.10 32 232 5.7E-25 T 22-04-2016 HRM2_RS22985 22ed025daf9182b1324810965f54a6f5 205 TIGRFAM TIGR02081 metW: methionine biosynthesis protein MetW 2 196 2.2E-71 T 22-04-2016 IPR010743 Methionine biosynthesis MetW HRM2_RS22985 22ed025daf9182b1324810965f54a6f5 205 Pfam PF07021 Methionine biosynthesis protein MetW 2 196 1.4E-71 T 22-04-2016 IPR010743 Methionine biosynthesis MetW HRM2_RS22985 22ed025daf9182b1324810965f54a6f5 205 PANTHER PTHR10108 1 163 1.5E-48 T 22-04-2016 HRM2_RS22985 22ed025daf9182b1324810965f54a6f5 205 PANTHER PTHR10108:SF831 1 163 1.5E-48 T 22-04-2016 HRM2_RS22985 22ed025daf9182b1324810965f54a6f5 205 SUPERFAMILY SSF53335 5 169 4.65E-24 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS22985 22ed025daf9182b1324810965f54a6f5 205 Gene3D G3DSA:3.40.50.150 12 184 4.2E-25 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS03675 b8849665a87b59464a33bf418837b470 1066 SUPERFAMILY SSF55785 743 843 1.93E-12 T 22-04-2016 IPR000014 PAS domain HRM2_RS03675 b8849665a87b59464a33bf418837b470 1066 SUPERFAMILY SSF55785 281 386 2.09E-10 T 22-04-2016 IPR000014 PAS domain HRM2_RS03675 b8849665a87b59464a33bf418837b470 1066 Pfam PF13188 PAS domain 733 777 6.9E-7 T 22-04-2016 IPR000014 PAS domain HRM2_RS03675 b8849665a87b59464a33bf418837b470 1066 Pfam PF13185 GAF domain 581 726 2.9E-10 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS03675 b8849665a87b59464a33bf418837b470 1066 Pfam PF13426 PAS domain 178 257 1.6E-5 T 22-04-2016 IPR000014 PAS domain HRM2_RS03675 b8849665a87b59464a33bf418837b470 1066 Pfam PF13426 PAS domain 288 386 2.7E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS03675 b8849665a87b59464a33bf418837b470 1066 PANTHER PTHR24423 730 992 4.8E-15 T 22-04-2016 HRM2_RS03675 b8849665a87b59464a33bf418837b470 1066 PANTHER PTHR24423 280 387 4.8E-15 T 22-04-2016 HRM2_RS03675 b8849665a87b59464a33bf418837b470 1066 PANTHER PTHR24423 482 497 4.8E-15 T 22-04-2016 HRM2_RS03675 b8849665a87b59464a33bf418837b470 1066 SMART SM00091 165 229 3.7E-4 T 22-04-2016 IPR000014 PAS domain HRM2_RS03675 b8849665a87b59464a33bf418837b470 1066 SMART SM00091 277 342 6.0 T 22-04-2016 IPR000014 PAS domain HRM2_RS03675 b8849665a87b59464a33bf418837b470 1066 SMART SM00091 732 799 1.0E-4 T 22-04-2016 IPR000014 PAS domain HRM2_RS03675 b8849665a87b59464a33bf418837b470 1066 Gene3D G3DSA:3.30.450.20 281 387 2.1E-11 T 22-04-2016 HRM2_RS03675 b8849665a87b59464a33bf418837b470 1066 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 281 387 1.1E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS03675 b8849665a87b59464a33bf418837b470 1066 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 167 273 1.7E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS03675 b8849665a87b59464a33bf418837b470 1066 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 732 843 1.6E-10 T 22-04-2016 IPR000014 PAS domain HRM2_RS03675 b8849665a87b59464a33bf418837b470 1066 Gene3D G3DSA:3.30.450.20 168 269 6.5E-8 T 22-04-2016 HRM2_RS03675 b8849665a87b59464a33bf418837b470 1066 Gene3D G3DSA:3.30.450.20 730 835 7.4E-15 T 22-04-2016 HRM2_RS03675 b8849665a87b59464a33bf418837b470 1066 SUPERFAMILY SSF55781 565 730 1.31E-17 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS03675 b8849665a87b59464a33bf418837b470 1066 SUPERFAMILY SSF55785 167 272 3.22E-7 T 22-04-2016 IPR000014 PAS domain HRM2_RS03675 b8849665a87b59464a33bf418837b470 1066 Gene3D G3DSA:3.30.450.40 572 728 3.0E-17 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS00965 a97630e9b138a21f23ffa5777f0216b4 298 PANTHER PTHR30293:SF2 2 291 1.9E-72 T 22-04-2016 HRM2_RS00965 a97630e9b138a21f23ffa5777f0216b4 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 64 1.9E-16 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HRM2_RS00965 a97630e9b138a21f23ffa5777f0216b4 298 Pfam PF03466 LysR substrate binding domain 96 294 4.9E-6 T 22-04-2016 IPR005119 LysR, substrate-binding HRM2_RS00965 a97630e9b138a21f23ffa5777f0216b4 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 3.94E-6 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HRM2_RS00965 a97630e9b138a21f23ffa5777f0216b4 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 3.94E-6 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HRM2_RS00965 a97630e9b138a21f23ffa5777f0216b4 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 3.94E-6 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HRM2_RS00965 a97630e9b138a21f23ffa5777f0216b4 298 Gene3D G3DSA:1.10.10.10 4 84 2.8E-20 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS00965 a97630e9b138a21f23ffa5777f0216b4 298 SUPERFAMILY SSF53850 96 294 1.19E-14 T 22-04-2016 HRM2_RS00965 a97630e9b138a21f23ffa5777f0216b4 298 SUPERFAMILY SSF46785 3 86 5.99E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS00965 a97630e9b138a21f23ffa5777f0216b4 298 PANTHER PTHR30293 2 291 1.9E-72 T 22-04-2016 HRM2_RS00965 a97630e9b138a21f23ffa5777f0216b4 298 Gene3D G3DSA:3.40.190.10 122 231 4.6E-5 T 22-04-2016 HRM2_RS21950 a17233b68c89c7f494079f44c9a34b51 1088 SMART SM00487 10 338 0.0046 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS21950 a17233b68c89c7f494079f44c9a34b51 1088 SUPERFAMILY SSF52540 898 962 3.63E-9 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21950 a17233b68c89c7f494079f44c9a34b51 1088 Pfam PF00271 Helicase conserved C-terminal domain 898 960 2.2E-6 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS21950 a17233b68c89c7f494079f44c9a34b51 1088 SUPERFAMILY SSF52540 13 132 8.04E-14 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21950 a17233b68c89c7f494079f44c9a34b51 1088 SUPERFAMILY SSF52540 256 309 8.04E-14 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21950 a17233b68c89c7f494079f44c9a34b51 1088 Gene3D G3DSA:3.40.50.300 196 205 3.3E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21950 a17233b68c89c7f494079f44c9a34b51 1088 Gene3D G3DSA:3.40.50.300 14 125 3.3E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21950 a17233b68c89c7f494079f44c9a34b51 1088 Gene3D G3DSA:3.40.50.300 264 312 3.3E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21950 a17233b68c89c7f494079f44c9a34b51 1088 Gene3D G3DSA:3.40.50.300 916 963 6.9E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12885 40b660ed7455134d38db7b3e4bfa2ee8 263 Gene3D G3DSA:3.40.50.720 1 257 4.8E-68 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS12885 40b660ed7455134d38db7b3e4bfa2ee8 263 PANTHER PTHR24319 1 263 2.4E-68 T 22-04-2016 HRM2_RS12885 40b660ed7455134d38db7b3e4bfa2ee8 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 3.7E-25 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS12885 40b660ed7455134d38db7b3e4bfa2ee8 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.7E-25 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS12885 40b660ed7455134d38db7b3e4bfa2ee8 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 3.7E-25 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS12885 40b660ed7455134d38db7b3e4bfa2ee8 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.7E-25 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS12885 40b660ed7455134d38db7b3e4bfa2ee8 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.7E-25 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS12885 40b660ed7455134d38db7b3e4bfa2ee8 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 3.7E-25 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS12885 40b660ed7455134d38db7b3e4bfa2ee8 263 SUPERFAMILY SSF51735 6 258 4.31E-66 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS12885 40b660ed7455134d38db7b3e4bfa2ee8 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 257 1.6E-46 T 22-04-2016 HRM2_RS12885 40b660ed7455134d38db7b3e4bfa2ee8 263 PANTHER PTHR24319:SF23 1 263 2.4E-68 T 22-04-2016 HRM2_RS09430 b6a3bf75309e8f587dfc505eb634ccc2 276 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 192 212 3.6E-6 T 22-04-2016 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 HRM2_RS09430 b6a3bf75309e8f587dfc505eb634ccc2 276 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 213 233 3.6E-6 T 22-04-2016 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 HRM2_RS09430 b6a3bf75309e8f587dfc505eb634ccc2 276 Pfam PF01578 Cytochrome C assembly protein 69 273 1.1E-58 T 22-04-2016 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 HRM2_RS09430 b6a3bf75309e8f587dfc505eb634ccc2 276 PANTHER PTHR30071 1 276 2.9E-87 T 22-04-2016 HRM2_RS09430 b6a3bf75309e8f587dfc505eb634ccc2 276 PANTHER PTHR30071:SF5 1 276 2.9E-87 T 22-04-2016 HRM2_RS09430 b6a3bf75309e8f587dfc505eb634ccc2 276 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 41 276 2.2E-86 T 22-04-2016 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 HRM2_RS03050 43f4291bb519462b018df8ef033896ee 253 Gene3D G3DSA:3.90.226.10 4 225 3.9E-42 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS03050 43f4291bb519462b018df8ef033896ee 253 PANTHER PTHR11941 1 199 2.4E-42 T 22-04-2016 HRM2_RS03050 43f4291bb519462b018df8ef033896ee 253 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 218 9.1E-33 T 22-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 HRM2_RS03050 43f4291bb519462b018df8ef033896ee 253 SUPERFAMILY SSF52096 5 249 2.38E-46 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS22995 29a7e9148f29280159e61246c211de54 253 PANTHER PTHR30292 1 253 1.1E-117 T 22-04-2016 HRM2_RS22995 29a7e9148f29280159e61246c211de54 253 SUPERFAMILY SSF88713 1 249 2.3E-94 T 22-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 HRM2_RS22995 29a7e9148f29280159e61246c211de54 253 Pfam PF03746 LamB/YcsF family 1 241 4.5E-100 T 22-04-2016 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF HRM2_RS22995 29a7e9148f29280159e61246c211de54 253 PANTHER PTHR30292:SF0 1 253 1.1E-117 T 22-04-2016 HRM2_RS22995 29a7e9148f29280159e61246c211de54 253 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 246 43.843 T 22-04-2016 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF HRM2_RS18735 018ab68edda02d6d318eca19468c61f3 869 SUPERFAMILY SSF56801 478 853 6.02E-19 T 22-04-2016 HRM2_RS18735 018ab68edda02d6d318eca19468c61f3 869 Gene3D G3DSA:3.30.300.30 770 866 4.0E-7 T 22-04-2016 HRM2_RS18735 018ab68edda02d6d318eca19468c61f3 869 SUPERFAMILY SSF53720 38 303 5.1E-8 T 22-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 HRM2_RS18735 018ab68edda02d6d318eca19468c61f3 869 PANTHER PTHR36932 456 761 3.4E-25 T 22-04-2016 HRM2_RS18735 018ab68edda02d6d318eca19468c61f3 869 PANTHER PTHR36932:SF1 456 761 3.4E-25 T 22-04-2016 HRM2_RS18735 018ab68edda02d6d318eca19468c61f3 869 Pfam PF05893 Acyl-CoA reductase (LuxC) 41 440 1.2E-66 T 22-04-2016 IPR008670 Acyl-CoA reductase, LuxC GO:0003995|GO:0008218|GO:0055114 KEGG: 00073+1.2.1.50|MetaCyc: PWY-7723|UniPathway: UPA00569 HRM2_RS18735 018ab68edda02d6d318eca19468c61f3 869 Gene3D G3DSA:3.40.50.980 531 684 1.5E-4 T 22-04-2016 HRM2_RS16595 d523bee45016b7fe7f40ec2c8141b778 596 PANTHER PTHR11615:SF139 17 591 8.4E-55 T 22-04-2016 HRM2_RS16595 d523bee45016b7fe7f40ec2c8141b778 596 Gene3D G3DSA:3.40.228.10 9 195 1.1E-61 T 22-04-2016 HRM2_RS16595 d523bee45016b7fe7f40ec2c8141b778 596 SUPERFAMILY SSF53706 2 463 5.1E-98 T 22-04-2016 HRM2_RS16595 d523bee45016b7fe7f40ec2c8141b778 596 PANTHER PTHR11615 17 591 8.4E-55 T 22-04-2016 HRM2_RS16595 d523bee45016b7fe7f40ec2c8141b778 596 SUPERFAMILY SSF50692 423 591 3.39E-33 T 22-04-2016 IPR009010 Aspartate decarboxylase-like domain HRM2_RS16595 d523bee45016b7fe7f40ec2c8141b778 596 Gene3D G3DSA:3.40.50.740 196 381 3.2E-23 T 22-04-2016 HRM2_RS16595 d523bee45016b7fe7f40ec2c8141b778 596 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 500 527 - T 22-04-2016 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 HRM2_RS16595 d523bee45016b7fe7f40ec2c8141b778 596 Pfam PF01568 Molydopterin dinucleotide binding domain 464 569 1.7E-19 T 22-04-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 HRM2_RS16595 d523bee45016b7fe7f40ec2c8141b778 596 Pfam PF00384 Molybdopterin oxidoreductase 26 353 1.5E-39 T 22-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 HRM2_RS16595 d523bee45016b7fe7f40ec2c8141b778 596 Gene3D G3DSA:2.40.40.20 436 594 2.0E-33 T 22-04-2016 HRM2_RS19290 549fbc914ffb7b7856313031da324fae 142 SMART SM00450 30 138 1.3E-6 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS19290 549fbc914ffb7b7856313031da324fae 142 Gene3D G3DSA:3.40.250.10 23 133 6.1E-15 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS19290 549fbc914ffb7b7856313031da324fae 142 SUPERFAMILY SSF52821 9 132 5.21E-15 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS19290 549fbc914ffb7b7856313031da324fae 142 Pfam PF00581 Rhodanese-like domain 30 132 3.1E-10 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS17155 5b40845d9fb6243f1c278ce967bf2b32 368 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 16 333 1.2E-9 T 22-04-2016 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 HRM2_RS17155 5b40845d9fb6243f1c278ce967bf2b32 368 Gene3D G3DSA:3.20.20.210 15 363 8.6E-62 T 22-04-2016 HRM2_RS17155 5b40845d9fb6243f1c278ce967bf2b32 368 PANTHER PTHR30519:SF10 15 368 3.6E-114 T 22-04-2016 HRM2_RS17155 5b40845d9fb6243f1c278ce967bf2b32 368 SUPERFAMILY SSF51726 15 359 2.35E-45 T 22-04-2016 HRM2_RS17155 5b40845d9fb6243f1c278ce967bf2b32 368 PANTHER PTHR30519 15 368 3.6E-114 T 22-04-2016 HRM2_RS12550 3427df9dd710c8e5da5f9abb53af169a 182 SUPERFAMILY SSF51182 1 179 3.28E-78 T 22-04-2016 IPR011051 RmlC-like cupin domain HRM2_RS12550 3427df9dd710c8e5da5f9abb53af169a 182 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 4 178 7.9E-82 T 22-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 HRM2_RS12550 3427df9dd710c8e5da5f9abb53af169a 182 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 181 2.0E-66 T 22-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 HRM2_RS12550 3427df9dd710c8e5da5f9abb53af169a 182 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 175 1.6E-74 T 22-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 HRM2_RS12550 3427df9dd710c8e5da5f9abb53af169a 182 PANTHER PTHR21047 1 182 1.6E-72 T 22-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 HRM2_RS12550 3427df9dd710c8e5da5f9abb53af169a 182 Gene3D G3DSA:2.60.120.10 1 179 1.9E-81 T 22-04-2016 IPR014710 RmlC-like jelly roll fold HRM2_RS15650 979b8b2b3388bcded5c5ac04f8ce392f 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 2.5E-37 T 22-04-2016 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS15650 979b8b2b3388bcded5c5ac04f8ce392f 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 26.741 T 22-04-2016 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS15650 979b8b2b3388bcded5c5ac04f8ce392f 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 22-04-2016 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS15650 979b8b2b3388bcded5c5ac04f8ce392f 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 1.1E-40 T 22-04-2016 IPR028909 Ribosomal protein L21-like GO:0005840 HRM2_RS15650 979b8b2b3388bcded5c5ac04f8ce392f 103 SUPERFAMILY SSF141091 1 102 8.76E-38 T 22-04-2016 IPR028909 Ribosomal protein L21-like GO:0005840 HRM2_RS15650 979b8b2b3388bcded5c5ac04f8ce392f 103 PANTHER PTHR21349 1 103 1.6E-39 T 22-04-2016 HRM2_RS19445 b8d8a436c7a3afd2df91449af7cb2826 177 Pfam PF02830 V4R domain 109 169 6.2E-17 T 22-04-2016 IPR004096 4-vinyl reductase, 4VR HRM2_RS19445 b8d8a436c7a3afd2df91449af7cb2826 177 Gene3D G3DSA:3.30.1380.20 1 173 2.7E-38 T 22-04-2016 HRM2_RS19445 b8d8a436c7a3afd2df91449af7cb2826 177 SMART SM00989 107 169 2.1E-23 T 22-04-2016 IPR004096 4-vinyl reductase, 4VR HRM2_RS19445 b8d8a436c7a3afd2df91449af7cb2826 177 SUPERFAMILY SSF111126 5 168 3.77E-29 T 22-04-2016 IPR024096 NO signalling/Golgi transport ligand-binding domain HRM2_RS19845 d45b6909f6fe8fd0bda7efa81cafb51e 496 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 377 486 3.0E-17 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS19845 d45b6909f6fe8fd0bda7efa81cafb51e 496 SUPERFAMILY SSF47384 263 331 5.89E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS19845 d45b6909f6fe8fd0bda7efa81cafb51e 496 PANTHER PTHR24423 245 487 9.9E-62 T 22-04-2016 HRM2_RS19845 d45b6909f6fe8fd0bda7efa81cafb51e 496 PANTHER PTHR24423:SF445 245 487 9.9E-62 T 22-04-2016 HRM2_RS19845 d45b6909f6fe8fd0bda7efa81cafb51e 496 SMART SM00388 268 334 7.1E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS19845 d45b6909f6fe8fd0bda7efa81cafb51e 496 SUPERFAMILY SSF55874 325 485 4.98E-37 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS19845 d45b6909f6fe8fd0bda7efa81cafb51e 496 Pfam PF12729 Four helix bundle sensory module for signal transduction 5 144 3.5E-10 T 22-04-2016 IPR024478 4HB MCP domain HRM2_RS19845 d45b6909f6fe8fd0bda7efa81cafb51e 496 Pfam PF00512 His Kinase A (phospho-acceptor) domain 270 330 1.0E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS19845 d45b6909f6fe8fd0bda7efa81cafb51e 496 SMART SM00387 376 487 1.8E-28 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS19845 d45b6909f6fe8fd0bda7efa81cafb51e 496 Gene3D G3DSA:1.10.287.130 269 330 4.1E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS19845 d45b6909f6fe8fd0bda7efa81cafb51e 496 Gene3D G3DSA:3.30.565.10 333 486 3.3E-37 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS19845 d45b6909f6fe8fd0bda7efa81cafb51e 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 432 2.2E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS19845 d45b6909f6fe8fd0bda7efa81cafb51e 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 465 2.2E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS19845 d45b6909f6fe8fd0bda7efa81cafb51e 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 436 446 2.2E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS19845 d45b6909f6fe8fd0bda7efa81cafb51e 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 471 484 2.2E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS04525 d6d78ada0775bfe8695c1fca2d69c650 207 PANTHER PTHR19136 1 194 8.8E-33 T 22-04-2016 HRM2_RS04525 d6d78ada0775bfe8695c1fca2d69c650 207 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 3 193 21.813 T 22-04-2016 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 MetaCyc: PWY-5964|MetaCyc: PWY-7639 HRM2_RS04525 d6d78ada0775bfe8695c1fca2d69c650 207 PANTHER PTHR19136:SF81 1 194 8.8E-33 T 22-04-2016 HRM2_RS04525 d6d78ada0775bfe8695c1fca2d69c650 207 Gene3D G3DSA:3.90.550.10 4 197 6.8E-43 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS04525 d6d78ada0775bfe8695c1fca2d69c650 207 SUPERFAMILY SSF53448 5 191 1.58E-26 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS04525 d6d78ada0775bfe8695c1fca2d69c650 207 Pfam PF12804 MobA-like NTP transferase domain 7 148 3.6E-24 T 22-04-2016 IPR025877 MobA-like NTP transferase HRM2_RS16415 19c58585217c8c407101d8a2b55c7c7a 135 Pfam PF00583 Acetyltransferase (GNAT) family 25 87 6.5E-9 T 22-04-2016 IPR000182 GNAT domain GO:0008080 HRM2_RS16415 19c58585217c8c407101d8a2b55c7c7a 135 PANTHER PTHR30602 1 126 5.4E-31 T 22-04-2016 HRM2_RS16415 19c58585217c8c407101d8a2b55c7c7a 135 SUPERFAMILY SSF55729 19 127 4.39E-15 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS16415 19c58585217c8c407101d8a2b55c7c7a 135 Gene3D G3DSA:3.40.630.30 4 122 5.8E-24 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS25125 33daf7206f5e3c40180c4d436f010dfd 255 Gene3D G3DSA:3.10.129.10 12 136 2.0E-27 T 22-04-2016 IPR029069 HotDog domain HRM2_RS25125 33daf7206f5e3c40180c4d436f010dfd 255 SUPERFAMILY SSF54637 11 134 2.51E-30 T 22-04-2016 IPR029069 HotDog domain HRM2_RS25125 33daf7206f5e3c40180c4d436f010dfd 255 Gene3D G3DSA:3.10.129.10 153 250 2.4E-21 T 22-04-2016 IPR029069 HotDog domain HRM2_RS25125 33daf7206f5e3c40180c4d436f010dfd 255 Pfam PF01643 Acyl-ACP thioesterase 13 250 6.3E-54 T 22-04-2016 IPR002864 Acyl-ACP thioesterase GO:0006633|GO:0016790 HRM2_RS25125 33daf7206f5e3c40180c4d436f010dfd 255 PANTHER PTHR31727:SF6 27 227 1.6E-30 T 22-04-2016 HRM2_RS25125 33daf7206f5e3c40180c4d436f010dfd 255 PANTHER PTHR31727 27 227 1.6E-30 T 22-04-2016 HRM2_RS25125 33daf7206f5e3c40180c4d436f010dfd 255 SUPERFAMILY SSF54637 148 253 2.66E-22 T 22-04-2016 IPR029069 HotDog domain HRM2_RS08290 ed5d579af04df1a820f60257b2c02caf 433 SUPERFAMILY SSF51717 69 247 1.69E-10 T 22-04-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 HRM2_RS08290 ed5d579af04df1a820f60257b2c02caf 433 PANTHER PTHR36214:SF5 26 306 4.8E-49 T 22-04-2016 HRM2_RS08290 ed5d579af04df1a820f60257b2c02caf 433 Pfam PF03599 CO dehydrogenase/acetyl-CoA synthase delta subunit 17 301 4.9E-46 T 22-04-2016 IPR016041 CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel HRM2_RS08290 ed5d579af04df1a820f60257b2c02caf 433 PANTHER PTHR36214 26 306 4.8E-49 T 22-04-2016 HRM2_RS02120 29d716ca19ec135c783d836d0e725348 312 PANTHER PTHR31528 1 301 3.5E-64 T 22-04-2016 IPR027939 NMT1/THI5 family GO:0009228 UniPathway: UPA00060 HRM2_RS02120 29d716ca19ec135c783d836d0e725348 312 SUPERFAMILY SSF53850 27 303 1.39E-35 T 22-04-2016 HRM2_RS02120 29d716ca19ec135c783d836d0e725348 312 PANTHER PTHR31528:SF5 1 301 3.5E-64 T 22-04-2016 HRM2_RS02120 29d716ca19ec135c783d836d0e725348 312 Pfam PF09084 NMT1/THI5 like 35 246 1.0E-53 T 22-04-2016 IPR015168 SsuA/THI5-like HRM2_RS02120 29d716ca19ec135c783d836d0e725348 312 Gene3D G3DSA:3.40.190.10 115 215 1.1E-9 T 22-04-2016 HRM2_RS15890 bf7e288402342fdf7daeb969be20d320 537 TIGRFAM TIGR02098 MJ0042_CXXC: MJ0042 family finger-like domain 1 38 3.9E-10 T 22-04-2016 IPR011723 Zinc finger/thioredoxin putative HRM2_RS15890 bf7e288402342fdf7daeb969be20d320 537 Pfam PF13719 zinc-ribbon domain 1 37 5.4E-14 T 22-04-2016 IPR011723 Zinc finger/thioredoxin putative HRM2_RS15890 bf7e288402342fdf7daeb969be20d320 537 Pfam PF11906 Protein of unknown function (DUF3426) 363 529 1.7E-13 T 22-04-2016 IPR021834 Protein of unknown function DUF3426 HRM2_RS17030 f521331941b0f33ae68c1e5eb89a6ac1 170 PANTHER PTHR35147 18 163 5.1E-25 T 22-04-2016 HRM2_RS17030 f521331941b0f33ae68c1e5eb89a6ac1 170 PANTHER PTHR35147:SF2 18 163 5.1E-25 T 22-04-2016 HRM2_RS17030 f521331941b0f33ae68c1e5eb89a6ac1 170 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 10 161 22.743 T 22-04-2016 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 HRM2_RS17030 f521331941b0f33ae68c1e5eb89a6ac1 170 Pfam PF03975 CheD chemotactic sensory transduction 68 155 9.4E-20 T 22-04-2016 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 HRM2_RS17030 f521331941b0f33ae68c1e5eb89a6ac1 170 SUPERFAMILY SSF64438 15 163 5.22E-38 T 22-04-2016 IPR011324 Cytotoxic necrotizing factor-like, catalytic HRM2_RS13020 cd725a664450be680437ef4ae35ec820 534 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 127 137 - T 22-04-2016 IPR022398 Peptidase S8, subtilisin, His-active site HRM2_RS13020 cd725a664450be680437ef4ae35ec820 534 Pfam PF00082 Subtilase family 88 329 5.4E-37 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HRM2_RS13020 cd725a664450be680437ef4ae35ec820 534 PANTHER PTHR10795 36 337 7.8E-59 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related HRM2_RS13020 cd725a664450be680437ef4ae35ec820 534 SUPERFAMILY SSF52743 66 337 6.02E-83 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HRM2_RS13020 cd725a664450be680437ef4ae35ec820 534 PANTHER PTHR10795:SF356 36 337 7.8E-59 T 22-04-2016 HRM2_RS13020 cd725a664450be680437ef4ae35ec820 534 PRINTS PR00723 Subtilisin serine protease family (S8) signature 278 294 1.5E-15 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related HRM2_RS13020 cd725a664450be680437ef4ae35ec820 534 PRINTS PR00723 Subtilisin serine protease family (S8) signature 85 104 1.5E-15 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related HRM2_RS13020 cd725a664450be680437ef4ae35ec820 534 PRINTS PR00723 Subtilisin serine protease family (S8) signature 123 136 1.5E-15 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related HRM2_RS13020 cd725a664450be680437ef4ae35ec820 534 Gene3D G3DSA:3.40.50.200 35 336 2.8E-90 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HRM2_RS13020 cd725a664450be680437ef4ae35ec820 534 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 279 289 - T 22-04-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site HRM2_RS13020 cd725a664450be680437ef4ae35ec820 534 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 90 101 - T 22-04-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site HRM2_RS19955 87b9f10b51efb982af4167f5bbb4d21e 77 Pfam PF12843 Putative quorum-sensing-regulated virulence factor 14 76 5.7E-30 T 22-04-2016 IPR024530 Putative quorum-sensing-regulated virulence factor HRM2_RS19955 87b9f10b51efb982af4167f5bbb4d21e 77 ProDom PD056452 UNCHARACTERIZED BACTERIA SIMILAR YPEB CYTOPLASMIC VCA0163 PRODUCT STM2426 GENE YPO2988 23 76 4.0E-19 T 22-04-2016 IPR024530 Putative quorum-sensing-regulated virulence factor HRM2_RS19955 87b9f10b51efb982af4167f5bbb4d21e 77 PANTHER PTHR40613 11 77 1.1E-24 T 22-04-2016 HRM2_RS19955 87b9f10b51efb982af4167f5bbb4d21e 77 PANTHER PTHR40613:SF1 11 77 1.1E-24 T 22-04-2016 HRM2_RS22575 12f209298d8cbed24a108883c5b4c4c3 232 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 140 228 1.5E-25 T 22-04-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 HRM2_RS22575 12f209298d8cbed24a108883c5b4c4c3 232 PANTHER PTHR10516 110 230 1.6E-57 T 22-04-2016 IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type HRM2_RS22575 12f209298d8cbed24a108883c5b4c4c3 232 Gene3D G3DSA:1.10.287.460 29 117 3.0E-25 T 22-04-2016 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 HRM2_RS22575 12f209298d8cbed24a108883c5b4c4c3 232 Gene3D G3DSA:3.10.50.40 118 230 4.4E-44 T 22-04-2016 HRM2_RS22575 12f209298d8cbed24a108883c5b4c4c3 232 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 25 133 3.7E-33 T 22-04-2016 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 HRM2_RS22575 12f209298d8cbed24a108883c5b4c4c3 232 PRINTS PR01730 Macrophage infectivity potentiator signature 75 89 4.4E-5 T 22-04-2016 IPR008104 Macrophage infectivity potentiator GO:0003755|GO:0016020 HRM2_RS22575 12f209298d8cbed24a108883c5b4c4c3 232 PRINTS PR01730 Macrophage infectivity potentiator signature 93 112 4.4E-5 T 22-04-2016 IPR008104 Macrophage infectivity potentiator GO:0003755|GO:0016020 HRM2_RS22575 12f209298d8cbed24a108883c5b4c4c3 232 PRINTS PR01730 Macrophage infectivity potentiator signature 28 42 4.4E-5 T 22-04-2016 IPR008104 Macrophage infectivity potentiator GO:0003755|GO:0016020 HRM2_RS22575 12f209298d8cbed24a108883c5b4c4c3 232 SUPERFAMILY SSF54534 31 230 1.11E-60 T 22-04-2016 HRM2_RS22575 12f209298d8cbed24a108883c5b4c4c3 232 PANTHER PTHR10516:SF320 110 230 1.6E-57 T 22-04-2016 HRM2_RS09240 d00e6b8f3f3402b05a9f31053d906e2c 703 Pfam PF00575 S1 RNA binding domain 632 701 1.2E-18 T 22-04-2016 IPR003029 S1 domain GO:0003676 HRM2_RS09240 d00e6b8f3f3402b05a9f31053d906e2c 703 Gene3D G3DSA:1.10.150.310 480 611 8.9E-45 T 22-04-2016 IPR023097 Tex RuvX-like domain HRM2_RS09240 d00e6b8f3f3402b05a9f31053d906e2c 703 PANTHER PTHR10724:SF1 1 702 5.2E-295 T 22-04-2016 HRM2_RS09240 d00e6b8f3f3402b05a9f31053d906e2c 703 Pfam PF16921 Tex protein YqgF-like domain 312 431 2.4E-43 T 22-04-2016 IPR032639 Tex protein, YqgF-like domain HRM2_RS09240 d00e6b8f3f3402b05a9f31053d906e2c 703 SUPERFAMILY SSF47781 451 539 1.22E-24 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 HRM2_RS09240 d00e6b8f3f3402b05a9f31053d906e2c 703 Gene3D G3DSA:3.30.420.140 311 431 2.1E-44 T 22-04-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 HRM2_RS09240 d00e6b8f3f3402b05a9f31053d906e2c 703 Gene3D G3DSA:2.40.50.140 621 702 3.0E-27 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS09240 d00e6b8f3f3402b05a9f31053d906e2c 703 SUPERFAMILY SSF53098 308 450 1.93E-45 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS09240 d00e6b8f3f3402b05a9f31053d906e2c 703 SUPERFAMILY SSF50249 614 702 1.57E-24 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS09240 d00e6b8f3f3402b05a9f31053d906e2c 703 Pfam PF12836 Helix-hairpin-helix motif 472 536 2.9E-25 T 22-04-2016 HRM2_RS09240 d00e6b8f3f3402b05a9f31053d906e2c 703 SMART SM00732 312 405 4.2E-26 T 22-04-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 HRM2_RS09240 d00e6b8f3f3402b05a9f31053d906e2c 703 Pfam PF09371 Tex-like protein N-terminal domain 5 188 2.2E-58 T 22-04-2016 IPR018974 Tex-like protein, N-terminal HRM2_RS09240 d00e6b8f3f3402b05a9f31053d906e2c 703 SUPERFAMILY SSF47781 541 612 3.11E-17 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 HRM2_RS09240 d00e6b8f3f3402b05a9f31053d906e2c 703 SMART SM00316 630 701 8.6E-24 T 22-04-2016 IPR022967 RNA-binding domain, S1 HRM2_RS09240 d00e6b8f3f3402b05a9f31053d906e2c 703 Gene3D G3DSA:1.10.3500.10 106 308 3.9E-89 T 22-04-2016 IPR023323 Tex-like domain HRM2_RS09240 d00e6b8f3f3402b05a9f31053d906e2c 703 Gene3D G3DSA:1.10.3500.10 432 479 3.9E-89 T 22-04-2016 IPR023323 Tex-like domain HRM2_RS09240 d00e6b8f3f3402b05a9f31053d906e2c 703 PANTHER PTHR10724 1 702 5.2E-295 T 22-04-2016 HRM2_RS09240 d00e6b8f3f3402b05a9f31053d906e2c 703 SUPERFAMILY SSF158832 2 305 4.05E-96 T 22-04-2016 HRM2_RS09240 d00e6b8f3f3402b05a9f31053d906e2c 703 Gene3D G3DSA:1.10.10.650 2 105 1.1E-32 T 22-04-2016 IPR023319 Tex-like protein, HTH domain HRM2_RS09225 9ad832b92ddb4c0260ca8f03988e142a 517 PANTHER PTHR24322 164 254 2.7E-64 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS09225 9ad832b92ddb4c0260ca8f03988e142a 517 PANTHER PTHR24322 364 406 2.7E-64 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS09225 9ad832b92ddb4c0260ca8f03988e142a 517 PANTHER PTHR24322 426 458 2.7E-64 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS09225 9ad832b92ddb4c0260ca8f03988e142a 517 Pfam PF00106 short chain dehydrogenase 161 252 7.0E-10 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS09225 9ad832b92ddb4c0260ca8f03988e142a 517 Gene3D G3DSA:3.40.50.720 356 491 3.7E-48 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS09225 9ad832b92ddb4c0260ca8f03988e142a 517 Gene3D G3DSA:3.40.50.720 142 247 3.7E-48 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS09225 9ad832b92ddb4c0260ca8f03988e142a 517 SUPERFAMILY SSF51735 361 493 1.45E-30 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS09225 9ad832b92ddb4c0260ca8f03988e142a 517 SUPERFAMILY SSF51735 156 255 1.45E-30 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS09225 9ad832b92ddb4c0260ca8f03988e142a 517 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 365 473 7.4E-11 T 22-04-2016 HRM2_RS09225 9ad832b92ddb4c0260ca8f03988e142a 517 PANTHER PTHR24322:SF506 164 254 2.7E-64 T 22-04-2016 HRM2_RS09225 9ad832b92ddb4c0260ca8f03988e142a 517 PANTHER PTHR24322:SF506 364 406 2.7E-64 T 22-04-2016 HRM2_RS09225 9ad832b92ddb4c0260ca8f03988e142a 517 PANTHER PTHR24322:SF506 426 458 2.7E-64 T 22-04-2016 HRM2_RS18450 9fabb212e2d43425673f460f9780d773 498 PANTHER PTHR26402 377 393 1.4E-33 T 22-04-2016 HRM2_RS18450 9fabb212e2d43425673f460f9780d773 498 PANTHER PTHR26402 7 136 1.4E-33 T 22-04-2016 HRM2_RS18450 9fabb212e2d43425673f460f9780d773 498 SMART SM00448 7 118 4.5E-30 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18450 9fabb212e2d43425673f460f9780d773 498 Pfam PF01966 HD domain 336 456 1.9E-21 T 22-04-2016 IPR006674 HD domain HRM2_RS18450 9fabb212e2d43425673f460f9780d773 498 SUPERFAMILY SSF55781 154 312 2.18E-14 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS18450 9fabb212e2d43425673f460f9780d773 498 Gene3D G3DSA:1.10.3210.10 330 493 9.7E-25 T 22-04-2016 IPR006674 HD domain HRM2_RS18450 9fabb212e2d43425673f460f9780d773 498 SMART SM00471 330 465 1.1E-13 T 22-04-2016 IPR003607 HD/PDEase domain HRM2_RS18450 9fabb212e2d43425673f460f9780d773 498 TIGRFAM TIGR00277 HDIG: HDIG domain 332 424 5.5E-9 T 22-04-2016 IPR006675 HDIG domain HRM2_RS18450 9fabb212e2d43425673f460f9780d773 498 SUPERFAMILY SSF109604 320 495 2.62E-40 T 22-04-2016 HRM2_RS18450 9fabb212e2d43425673f460f9780d773 498 SUPERFAMILY SSF52172 8 142 8.25E-37 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS18450 9fabb212e2d43425673f460f9780d773 498 Gene3D G3DSA:3.40.50.2300 5 125 8.8E-35 T 22-04-2016 HRM2_RS18450 9fabb212e2d43425673f460f9780d773 498 Pfam PF13185 GAF domain 172 304 8.9E-7 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS18450 9fabb212e2d43425673f460f9780d773 498 Pfam PF00072 Response regulator receiver domain 9 115 2.9E-27 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18450 9fabb212e2d43425673f460f9780d773 498 Gene3D G3DSA:3.30.450.40 150 311 8.9E-18 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS16235 25cadfa5a8c4fa0d3d6ac78a42a0b2c9 487 Gene3D G3DSA:3.40.1700.10 110 236 3.5E-41 T 22-04-2016 HRM2_RS16235 25cadfa5a8c4fa0d3d6ac78a42a0b2c9 487 SUPERFAMILY SSF143597 42 235 3.01E-50 T 22-04-2016 HRM2_RS16235 25cadfa5a8c4fa0d3d6ac78a42a0b2c9 487 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 116 233 3.0E-36 T 22-04-2016 IPR003390 DNA integrity scanning protein, DisA, N-terminal HRM2_RS16235 25cadfa5a8c4fa0d3d6ac78a42a0b2c9 487 Pfam PF07949 YbbR-like protein 297 380 1.1E-6 T 22-04-2016 IPR012505 YbbR-like HRM2_RS16235 25cadfa5a8c4fa0d3d6ac78a42a0b2c9 487 PANTHER PTHR34185:SF1 1 274 4.6E-55 T 22-04-2016 HRM2_RS16235 25cadfa5a8c4fa0d3d6ac78a42a0b2c9 487 PANTHER PTHR34185 1 274 4.6E-55 T 22-04-2016 HRM2_RS11690 eb7505ad937eedbcd0110351381beb99 239 Gene3D G3DSA:1.20.1540.10 11 200 1.0E-27 T 22-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 HRM2_RS11690 eb7505ad937eedbcd0110351381beb99 239 PANTHER PTHR22936 7 207 1.4E-30 T 22-04-2016 IPR002610 Peptidase S54, rhomboid GO:0004252|GO:0006508|GO:0016021 HRM2_RS11690 eb7505ad937eedbcd0110351381beb99 239 Pfam PF01694 Rhomboid family 64 202 2.4E-25 T 22-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 HRM2_RS11690 eb7505ad937eedbcd0110351381beb99 239 SUPERFAMILY SSF144091 9 207 8.24E-33 T 22-04-2016 HRM2_RS11385 1b7eea3fbf570025c7568095a80bfd8b 311 Pfam PF04015 Domain of unknown function (DUF362) 77 274 9.3E-41 T 22-04-2016 IPR007160 Domain of unknown function DUF362 HRM2_RS04455 9c95b6f2f3f13122094ec82c2a831616 355 SMART SM00382 120 293 2.7E-5 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS04455 9c95b6f2f3f13122094ec82c2a831616 355 SUPERFAMILY SSF50249 5 76 2.4E-15 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS04455 9c95b6f2f3f13122094ec82c2a831616 355 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 110 314 1.2E-18 T 22-04-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS04455 9c95b6f2f3f13122094ec82c2a831616 355 SMART SM00357 5 71 0.0011 T 22-04-2016 IPR011129 Cold shock protein GO:0003676 HRM2_RS04455 9c95b6f2f3f13122094ec82c2a831616 355 Gene3D G3DSA:2.40.50.140 3 78 8.7E-20 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS04455 9c95b6f2f3f13122094ec82c2a831616 355 Pfam PF07497 Rho termination factor, RNA-binding domain 5 76 7.9E-20 T 22-04-2016 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 HRM2_RS04455 9c95b6f2f3f13122094ec82c2a831616 355 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 355 129.32 T 22-04-2016 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 HRM2_RS04455 9c95b6f2f3f13122094ec82c2a831616 355 PANTHER PTHR15184:SF34 65 352 8.5E-114 T 22-04-2016 HRM2_RS04455 9c95b6f2f3f13122094ec82c2a831616 355 Gene3D G3DSA:3.40.50.300 91 352 3.8E-75 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04455 9c95b6f2f3f13122094ec82c2a831616 355 SUPERFAMILY SSF52540 72 322 4.15E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04455 9c95b6f2f3f13122094ec82c2a831616 355 PANTHER PTHR15184 65 352 8.5E-114 T 22-04-2016 HRM2_RS12045 1fce1835bdaf2ed78b269729c33caee2 219 Gene3D G3DSA:3.40.50.2300 1 121 4.1E-39 T 22-04-2016 HRM2_RS12045 1fce1835bdaf2ed78b269729c33caee2 219 Pfam PF00072 Response regulator receiver domain 6 117 8.4E-31 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS12045 1fce1835bdaf2ed78b269729c33caee2 219 SUPERFAMILY SSF46894 144 217 3.74E-22 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HRM2_RS12045 1fce1835bdaf2ed78b269729c33caee2 219 SMART SM00421 153 210 6.0E-24 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS12045 1fce1835bdaf2ed78b269729c33caee2 219 PANTHER PTHR26402 4 218 1.3E-82 T 22-04-2016 HRM2_RS12045 1fce1835bdaf2ed78b269729c33caee2 219 SUPERFAMILY SSF52172 3 135 2.7E-36 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS12045 1fce1835bdaf2ed78b269729c33caee2 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 2.3E-14 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS12045 1fce1835bdaf2ed78b269729c33caee2 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 2.3E-14 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS12045 1fce1835bdaf2ed78b269729c33caee2 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 2.3E-14 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS12045 1fce1835bdaf2ed78b269729c33caee2 219 PANTHER PTHR26402:SF151 4 218 1.3E-82 T 22-04-2016 HRM2_RS12045 1fce1835bdaf2ed78b269729c33caee2 219 SMART SM00448 4 117 2.8E-34 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS12045 1fce1835bdaf2ed78b269729c33caee2 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 1.1E-19 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS12045 1fce1835bdaf2ed78b269729c33caee2 219 Gene3D G3DSA:1.10.10.10 122 217 3.6E-29 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS12045 1fce1835bdaf2ed78b269729c33caee2 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS05850 fcd1951d8437b6724639a5679b9da9a6 408 Gene3D G3DSA:3.30.565.10 238 405 1.2E-42 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS05850 fcd1951d8437b6724639a5679b9da9a6 408 PANTHER PTHR24423 177 404 2.7E-77 T 22-04-2016 HRM2_RS05850 fcd1951d8437b6724639a5679b9da9a6 408 PANTHER PTHR24423 9 28 2.7E-77 T 22-04-2016 HRM2_RS05850 fcd1951d8437b6724639a5679b9da9a6 408 Pfam PF13185 GAF domain 25 162 3.0E-7 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS05850 fcd1951d8437b6724639a5679b9da9a6 408 SUPERFAMILY SSF55874 242 401 9.95E-40 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS05850 fcd1951d8437b6724639a5679b9da9a6 408 PANTHER PTHR24423:SF450 177 404 2.7E-77 T 22-04-2016 HRM2_RS05850 fcd1951d8437b6724639a5679b9da9a6 408 PANTHER PTHR24423:SF450 9 28 2.7E-77 T 22-04-2016 HRM2_RS05850 fcd1951d8437b6724639a5679b9da9a6 408 SUPERFAMILY SSF55781 27 164 7.85E-16 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS05850 fcd1951d8437b6724639a5679b9da9a6 408 Gene3D G3DSA:1.10.287.130 183 237 1.0E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS05850 fcd1951d8437b6724639a5679b9da9a6 408 Pfam PF00512 His Kinase A (phospho-acceptor) domain 187 249 1.4E-15 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS05850 fcd1951d8437b6724639a5679b9da9a6 408 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 399 7.5E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS05850 fcd1951d8437b6724639a5679b9da9a6 408 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 361 7.5E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS05850 fcd1951d8437b6724639a5679b9da9a6 408 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 380 7.5E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS05850 fcd1951d8437b6724639a5679b9da9a6 408 PRINTS PR00344 Bacterial sensor protein C-terminal signature 333 347 7.5E-19 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS05850 fcd1951d8437b6724639a5679b9da9a6 408 SUPERFAMILY SSF47384 181 249 7.46E-15 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS05850 fcd1951d8437b6724639a5679b9da9a6 408 SMART SM00387 294 402 5.8E-33 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS05850 fcd1951d8437b6724639a5679b9da9a6 408 SMART SM00388 187 252 4.5E-15 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS05850 fcd1951d8437b6724639a5679b9da9a6 408 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 295 400 6.6E-23 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS05850 fcd1951d8437b6724639a5679b9da9a6 408 Gene3D G3DSA:3.30.450.40 2 166 2.0E-18 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS09790 77ffcd1c95e4c3b2c5a84356371a710c 174 TIGRFAM TIGR02914 EpsI_fam: EpsI family protein 3 171 3.4E-39 T 22-04-2016 IPR014263 Methanolan biosynthesis EpsI HRM2_RS09790 77ffcd1c95e4c3b2c5a84356371a710c 174 Pfam PF11984 Protein of unknown function (DUF3485) 2 171 3.2E-47 T 22-04-2016 IPR014263 Methanolan biosynthesis EpsI HRM2_RS13425 4efc0c1da7e2184d1fb67c10e9331032 108 SMART SM00411 3 92 8.1E-23 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 HRM2_RS13425 4efc0c1da7e2184d1fb67c10e9331032 108 Gene3D G3DSA:4.10.520.10 2 93 2.3E-27 T 22-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 HRM2_RS13425 4efc0c1da7e2184d1fb67c10e9331032 108 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 48 67 - T 22-04-2016 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 HRM2_RS13425 4efc0c1da7e2184d1fb67c10e9331032 108 PRINTS PR01727 Prokaryotic integration host factor signature 42 57 2.1E-8 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 HRM2_RS13425 4efc0c1da7e2184d1fb67c10e9331032 108 PRINTS PR01727 Prokaryotic integration host factor signature 76 90 2.1E-8 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 HRM2_RS13425 4efc0c1da7e2184d1fb67c10e9331032 108 PRINTS PR01727 Prokaryotic integration host factor signature 60 73 2.1E-8 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 HRM2_RS13425 4efc0c1da7e2184d1fb67c10e9331032 108 Pfam PF00216 Bacterial DNA-binding protein 3 92 5.7E-26 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 HRM2_RS13425 4efc0c1da7e2184d1fb67c10e9331032 108 PANTHER PTHR33175:SF2 2 103 3.5E-30 T 22-04-2016 HRM2_RS13425 4efc0c1da7e2184d1fb67c10e9331032 108 SUPERFAMILY SSF47729 3 94 2.36E-25 T 22-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 HRM2_RS13425 4efc0c1da7e2184d1fb67c10e9331032 108 PANTHER PTHR33175 2 103 3.5E-30 T 22-04-2016 HRM2_RS17510 a23589e89e0c8fb640c053dcfd1ab1c5 616 Hamap MF_00964 ATP-dependent RNA helicase DeaD [deaD]. 14 613 44.988 T 22-04-2016 IPR028618 ATP-dependent RNA helicase DeaD GO:0000027|GO:0004004|GO:0070417 HRM2_RS17510 a23589e89e0c8fb640c053dcfd1ab1c5 616 PANTHER PTHR24031:SF261 21 532 3.6E-227 T 22-04-2016 HRM2_RS17510 a23589e89e0c8fb640c053dcfd1ab1c5 616 SUPERFAMILY SSF52540 87 374 1.29E-74 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17510 a23589e89e0c8fb640c053dcfd1ab1c5 616 Pfam PF03880 DbpA RNA binding domain 541 611 1.9E-19 T 22-04-2016 IPR005580 DbpA, RNA-binding domain HRM2_RS17510 a23589e89e0c8fb640c053dcfd1ab1c5 616 Gene3D G3DSA:3.40.50.300 220 389 7.0E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17510 a23589e89e0c8fb640c053dcfd1ab1c5 616 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 167 175 - T 22-04-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site HRM2_RS17510 a23589e89e0c8fb640c053dcfd1ab1c5 616 SMART SM00487 38 236 3.7E-60 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS17510 a23589e89e0c8fb640c053dcfd1ab1c5 616 Pfam PF00270 DEAD/DEAH box helicase 43 210 9.8E-49 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HRM2_RS17510 a23589e89e0c8fb640c053dcfd1ab1c5 616 Pfam PF00271 Helicase conserved C-terminal domain 245 353 5.8E-30 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS17510 a23589e89e0c8fb640c053dcfd1ab1c5 616 PANTHER PTHR24031 21 532 3.6E-227 T 22-04-2016 HRM2_RS17510 a23589e89e0c8fb640c053dcfd1ab1c5 616 Gene3D G3DSA:3.40.50.300 12 219 8.3E-75 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17510 a23589e89e0c8fb640c053dcfd1ab1c5 616 SMART SM00490 272 353 3.8E-34 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS03870 2fc42a91d2aa1bd723d4c2297e09a241 137 ProDom PD016189 SYNTHETASE LIGASE THREONYL-TRNA AMINOACYL-TRNA NUCLEOTIDE-BINDING BIOSYNTHESIS ATP-BINDING ZINC METAL-BINDING THRRS 3 135 3.0E-26 T 22-04-2016 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 HRM2_RS03870 2fc42a91d2aa1bd723d4c2297e09a241 137 Pfam PF08915 Archaea-specific editing domain of threonyl-tRNA synthetase 3 136 2.0E-38 T 22-04-2016 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 HRM2_RS09895 d27881340925968ee68048f97c456e41 206 PANTHER PTHR23083 56 183 6.9E-15 T 22-04-2016 HRM2_RS09895 d27881340925968ee68048f97c456e41 206 Gene3D G3DSA:1.25.40.10 49 179 1.6E-20 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS09895 d27881340925968ee68048f97c456e41 206 SMART SM00028 47 80 0.27 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS09895 d27881340925968ee68048f97c456e41 206 SMART SM00028 81 114 71.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS09895 d27881340925968ee68048f97c456e41 206 SMART SM00028 148 181 150.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS09895 d27881340925968ee68048f97c456e41 206 SUPERFAMILY SSF48452 47 178 1.05E-20 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS09895 d27881340925968ee68048f97c456e41 206 Pfam PF13431 Tetratricopeptide repeat 71 102 5.9E-5 T 22-04-2016 HRM2_RS14715 79b9d3453499c238e8dd177cb60b162a 258 SUPERFAMILY SSF53448 2 257 4.71E-42 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS14715 79b9d3453499c238e8dd177cb60b162a 258 Pfam PF00535 Glycosyl transferase family 2 5 153 6.1E-16 T 22-04-2016 IPR001173 Glycosyltransferase 2-like HRM2_RS14715 79b9d3453499c238e8dd177cb60b162a 258 PANTHER PTHR22916 167 256 3.2E-49 T 22-04-2016 HRM2_RS14715 79b9d3453499c238e8dd177cb60b162a 258 PANTHER PTHR22916 1 140 3.2E-49 T 22-04-2016 HRM2_RS14715 79b9d3453499c238e8dd177cb60b162a 258 PANTHER PTHR22916:SF16 167 256 3.2E-49 T 22-04-2016 HRM2_RS14715 79b9d3453499c238e8dd177cb60b162a 258 PANTHER PTHR22916:SF16 1 140 3.2E-49 T 22-04-2016 HRM2_RS14715 79b9d3453499c238e8dd177cb60b162a 258 Gene3D G3DSA:3.90.550.10 4 254 5.5E-39 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS13995 9db4b4ee434ab017b311aa08ef0968ea 460 Gene3D G3DSA:3.30.465.10 96 216 1.0E-36 T 22-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 HRM2_RS13995 9db4b4ee434ab017b311aa08ef0968ea 460 SUPERFAMILY SSF55103 219 457 9.65E-67 T 22-04-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 HRM2_RS13995 9db4b4ee434ab017b311aa08ef0968ea 460 Gene3D G3DSA:3.30.43.10 1 95 1.1E-22 T 22-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 HRM2_RS13995 9db4b4ee434ab017b311aa08ef0968ea 460 Gene3D G3DSA:1.10.45.10 417 456 6.6E-9 T 22-04-2016 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 HRM2_RS13995 9db4b4ee434ab017b311aa08ef0968ea 460 SUPERFAMILY SSF56176 2 216 7.01E-63 T 22-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 HRM2_RS13995 9db4b4ee434ab017b311aa08ef0968ea 460 Pfam PF01565 FAD binding domain 40 177 1.6E-35 T 22-04-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 HRM2_RS13995 9db4b4ee434ab017b311aa08ef0968ea 460 Pfam PF02913 FAD linked oxidases, C-terminal domain 216 456 1.2E-69 T 22-04-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 HRM2_RS13995 9db4b4ee434ab017b311aa08ef0968ea 460 PANTHER PTHR11748 1 456 1.8E-146 T 22-04-2016 HRM2_RS13995 9db4b4ee434ab017b311aa08ef0968ea 460 PANTHER PTHR11748:SF78 1 456 1.8E-146 T 22-04-2016 HRM2_RS04170 978ef610fe8b8a7b219802868b8e2720 425 PANTHER PTHR33362 12 423 3.5E-155 T 22-04-2016 HRM2_RS04170 978ef610fe8b8a7b219802868b8e2720 425 PIRSF PIRSF006066 1 425 3.8E-151 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS04170 978ef610fe8b8a7b219802868b8e2720 425 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 16 420 1.4E-139 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS04170 978ef610fe8b8a7b219802868b8e2720 425 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 8 415 1.9E-122 T 22-04-2016 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit HRM2_RS04170 978ef610fe8b8a7b219802868b8e2720 425 PANTHER PTHR33362:SF6 12 423 3.5E-155 T 22-04-2016 HRM2_RS10595 351f108641c03c7d12953f98dfba3487 167 PANTHER PTHR37425 6 167 2.9E-41 T 22-04-2016 HRM2_RS10595 351f108641c03c7d12953f98dfba3487 167 SUPERFAMILY SSF55166 49 167 7.32E-30 T 22-04-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain HRM2_RS10595 351f108641c03c7d12953f98dfba3487 167 Gene3D G3DSA:3.30.1380.10 51 167 2.6E-27 T 22-04-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain HRM2_RS10595 351f108641c03c7d12953f98dfba3487 167 Pfam PF05951 Bacterial protein of unknown function (DUF882) 21 167 5.4E-53 T 22-04-2016 IPR010275 Protein of unknown function DUF882 HRM2_RS19600 432065585cb27661d1d0307b870fa3f7 257 SUPERFAMILY SSF57783 216 255 4.93E-7 T 22-04-2016 HRM2_RS19600 432065585cb27661d1d0307b870fa3f7 257 Pfam PF08378 Nuclease-related domain 33 145 7.6E-30 T 22-04-2016 IPR011528 Nuclease-related domain, NERD HRM2_RS19600 432065585cb27661d1d0307b870fa3f7 257 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 219 256 1.6E-9 T 22-04-2016 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 HRM2_RS19600 432065585cb27661d1d0307b870fa3f7 257 Gene3D G3DSA:3.30.65.10 219 254 1.3E-8 T 22-04-2016 HRM2_RS05635 7c8e1a6e113e3d8e9fc211f94e1cabc8 204 SMART SM00287 24 88 4.8E-5 T 22-04-2016 IPR003646 SH3-like domain, bacterial-type HRM2_RS05635 7c8e1a6e113e3d8e9fc211f94e1cabc8 204 Gene3D G3DSA:2.30.30.40 52 85 1.7E-4 T 22-04-2016 HRM2_RS05635 7c8e1a6e113e3d8e9fc211f94e1cabc8 204 TIGRFAM TIGR04211 SH3_and_anchor: SH3 domain protein 28 201 3.8E-43 T 22-04-2016 IPR016476 SH3 domain protein HRM2_RS05635 7c8e1a6e113e3d8e9fc211f94e1cabc8 204 Pfam PF08239 Bacterial SH3 domain 37 84 4.5E-11 T 22-04-2016 IPR003646 SH3-like domain, bacterial-type HRM2_RS15885 bd1d0a4304002ef0102b5409498e738e 171 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 7 168 4.7E-57 T 22-04-2016 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620|UniPathway: UPA00591 HRM2_RS15885 bd1d0a4304002ef0102b5409498e738e 171 PANTHER PTHR22573 1 170 1.1E-64 T 22-04-2016 HRM2_RS15885 bd1d0a4304002ef0102b5409498e738e 171 Pfam PF00156 Phosphoribosyl transferase domain 11 156 5.9E-27 T 22-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 HRM2_RS15885 bd1d0a4304002ef0102b5409498e738e 171 PANTHER PTHR22573:SF56 1 170 1.1E-64 T 22-04-2016 HRM2_RS15885 bd1d0a4304002ef0102b5409498e738e 171 SUPERFAMILY SSF53271 7 170 1.97E-50 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like HRM2_RS15885 bd1d0a4304002ef0102b5409498e738e 171 Gene3D G3DSA:3.40.50.2020 7 170 1.3E-66 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like HRM2_RS03495 af8771a6b37417af05f68701c9a5d0c7 504 Gene3D G3DSA:1.10.287.130 271 338 4.7E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS03495 af8771a6b37417af05f68701c9a5d0c7 504 SUPERFAMILY SSF158472 216 261 1.96E-6 T 22-04-2016 HRM2_RS03495 af8771a6b37417af05f68701c9a5d0c7 504 SMART SM00388 274 342 9.2E-15 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS03495 af8771a6b37417af05f68701c9a5d0c7 504 PANTHER PTHR24423 7 40 4.0E-71 T 22-04-2016 HRM2_RS03495 af8771a6b37417af05f68701c9a5d0c7 504 PANTHER PTHR24423 205 498 4.0E-71 T 22-04-2016 HRM2_RS03495 af8771a6b37417af05f68701c9a5d0c7 504 Gene3D G3DSA:3.30.565.10 343 492 2.0E-43 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS03495 af8771a6b37417af05f68701c9a5d0c7 504 Pfam PF00672 HAMP domain 195 260 1.8E-10 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS03495 af8771a6b37417af05f68701c9a5d0c7 504 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 472 7.7E-21 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS03495 af8771a6b37417af05f68701c9a5d0c7 504 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 451 7.7E-21 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS03495 af8771a6b37417af05f68701c9a5d0c7 504 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 437 7.7E-21 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS03495 af8771a6b37417af05f68701c9a5d0c7 504 PRINTS PR00344 Bacterial sensor protein C-terminal signature 478 491 7.7E-21 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS03495 af8771a6b37417af05f68701c9a5d0c7 504 SUPERFAMILY SSF55874 332 492 6.42E-42 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS03495 af8771a6b37417af05f68701c9a5d0c7 504 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 384 493 4.4E-26 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS03495 af8771a6b37417af05f68701c9a5d0c7 504 SMART SM00387 384 494 2.4E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS03495 af8771a6b37417af05f68701c9a5d0c7 504 Pfam PF00512 His Kinase A (phospho-acceptor) domain 276 341 2.9E-15 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS03495 af8771a6b37417af05f68701c9a5d0c7 504 SUPERFAMILY SSF47384 270 339 3.14E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS03495 af8771a6b37417af05f68701c9a5d0c7 504 SMART SM00304 211 264 3.8E-8 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS12250 dea85fbc27ddc5eb9220315d30ac2dab 189 Pfam PF02622 Uncharacterized ACR, COG1678 18 176 7.7E-42 T 22-04-2016 IPR003774 Protein of unknown function UPF0301 HRM2_RS12250 dea85fbc27ddc5eb9220315d30ac2dab 189 Gene3D G3DSA:3.30.70.1300 53 132 1.4E-18 T 22-04-2016 HRM2_RS12250 dea85fbc27ddc5eb9220315d30ac2dab 189 PANTHER PTHR30327 8 187 1.6E-40 T 22-04-2016 HRM2_RS12250 dea85fbc27ddc5eb9220315d30ac2dab 189 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 7 189 29.527 T 22-04-2016 IPR003774 Protein of unknown function UPF0301 HRM2_RS12250 dea85fbc27ddc5eb9220315d30ac2dab 189 SUPERFAMILY SSF143456 9 186 2.22E-50 T 22-04-2016 HRM2_RS12250 dea85fbc27ddc5eb9220315d30ac2dab 189 Gene3D G3DSA:3.40.1740.10 133 177 8.2E-28 T 22-04-2016 HRM2_RS12250 dea85fbc27ddc5eb9220315d30ac2dab 189 Gene3D G3DSA:3.40.1740.10 5 46 8.2E-28 T 22-04-2016 HRM2_RS12250 dea85fbc27ddc5eb9220315d30ac2dab 189 PANTHER PTHR30327:SF1 8 187 1.6E-40 T 22-04-2016 HRM2_RS14290 bb3603aa7e9f3cfc982a404d00751369 283 Gene3D G3DSA:3.60.15.10 4 103 4.7E-31 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS14290 bb3603aa7e9f3cfc982a404d00751369 283 Gene3D G3DSA:3.60.15.10 136 272 4.7E-31 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS14290 bb3603aa7e9f3cfc982a404d00751369 283 PANTHER PTHR13754 3 283 1.2E-70 T 22-04-2016 HRM2_RS14290 bb3603aa7e9f3cfc982a404d00751369 283 PANTHER PTHR13754:SF13 3 283 1.2E-70 T 22-04-2016 HRM2_RS14290 bb3603aa7e9f3cfc982a404d00751369 283 SMART SM00849 24 254 0.0072 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS14290 bb3603aa7e9f3cfc982a404d00751369 283 Pfam PF00753 Metallo-beta-lactamase superfamily 24 226 1.2E-13 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS14290 bb3603aa7e9f3cfc982a404d00751369 283 SUPERFAMILY SSF56281 146 279 6.29E-29 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS14290 bb3603aa7e9f3cfc982a404d00751369 283 SUPERFAMILY SSF56281 7 106 6.29E-29 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS19485 b954d0014dd5cf5fd9de4a3fb21b1fb8 499 PANTHER PTHR35004 2 401 8.8E-63 T 22-04-2016 HRM2_RS19485 b954d0014dd5cf5fd9de4a3fb21b1fb8 499 PANTHER PTHR35004:SF2 2 401 8.8E-63 T 22-04-2016 HRM2_RS19485 b954d0014dd5cf5fd9de4a3fb21b1fb8 499 Pfam PF00665 Integrase core domain 134 249 1.2E-8 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 HRM2_RS24125 85c812e85edf2649793c2db31e4bf931 371 SUPERFAMILY SSF53822 23 363 2.22E-83 T 22-04-2016 IPR028082 Periplasmic binding protein-like I HRM2_RS24125 85c812e85edf2649793c2db31e4bf931 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 25 41 2.12E-9 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HRM2_RS24125 85c812e85edf2649793c2db31e4bf931 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 47 63 2.12E-9 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HRM2_RS24125 85c812e85edf2649793c2db31e4bf931 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 252 270 2.12E-9 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HRM2_RS24125 85c812e85edf2649793c2db31e4bf931 371 PANTHER PTHR30483 4 367 5.4E-69 T 22-04-2016 HRM2_RS24125 85c812e85edf2649793c2db31e4bf931 371 Gene3D G3DSA:3.40.50.2300 24 219 2.8E-51 T 22-04-2016 HRM2_RS24125 85c812e85edf2649793c2db31e4bf931 371 Pfam PF13458 Periplasmic binding protein 24 353 5.4E-60 T 22-04-2016 IPR028081 Leucine-binding protein domain HRM2_RS12580 ed77710a4846795c5f89f86c65a88980 394 Gene3D G3DSA:1.10.1060.10 54 86 4.6E-5 T 22-04-2016 HRM2_RS12580 ed77710a4846795c5f89f86c65a88980 394 Pfam PF04422 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term 75 143 2.7E-7 T 22-04-2016 IPR007516 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal HRM2_RS12580 ed77710a4846795c5f89f86c65a88980 394 SUPERFAMILY SSF54862 12 62 1.26E-12 T 22-04-2016 HRM2_RS12580 ed77710a4846795c5f89f86c65a88980 394 Pfam PF12838 4Fe-4S dicluster domain 14 61 1.8E-9 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS12580 ed77710a4846795c5f89f86c65a88980 394 Pfam PF04432 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus 161 322 1.3E-27 T 22-04-2016 IPR007525 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal HRM2_RS12580 ed77710a4846795c5f89f86c65a88980 394 Gene3D G3DSA:3.30.70.20 13 53 1.9E-11 T 22-04-2016 HRM2_RS12580 ed77710a4846795c5f89f86c65a88980 394 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 49 60 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS17995 2cb77f223938f6700dee2a309886875a 593 Gene3D G3DSA:3.10.350.10 548 592 4.1E-13 T 22-04-2016 IPR018392 LysM domain HRM2_RS17995 2cb77f223938f6700dee2a309886875a 593 Gene3D G3DSA:3.10.350.10 494 539 1.1E-15 T 22-04-2016 IPR018392 LysM domain HRM2_RS17995 2cb77f223938f6700dee2a309886875a 593 Gene3D G3DSA:3.10.350.10 426 472 2.3E-12 T 22-04-2016 IPR018392 LysM domain HRM2_RS17995 2cb77f223938f6700dee2a309886875a 593 PANTHER PTHR21666:SF206 164 537 1.3E-68 T 22-04-2016 HRM2_RS17995 2cb77f223938f6700dee2a309886875a 593 Pfam PF01476 LysM domain 551 592 2.0E-9 T 22-04-2016 IPR018392 LysM domain HRM2_RS17995 2cb77f223938f6700dee2a309886875a 593 Pfam PF01476 LysM domain 496 538 1.7E-13 T 22-04-2016 IPR018392 LysM domain HRM2_RS17995 2cb77f223938f6700dee2a309886875a 593 Pfam PF01476 LysM domain 428 471 2.5E-9 T 22-04-2016 IPR018392 LysM domain HRM2_RS17995 2cb77f223938f6700dee2a309886875a 593 SUPERFAMILY SSF54106 494 538 1.7E-10 T 22-04-2016 IPR018392 LysM domain HRM2_RS17995 2cb77f223938f6700dee2a309886875a 593 SUPERFAMILY SSF54106 426 471 5.36E-9 T 22-04-2016 IPR018392 LysM domain HRM2_RS17995 2cb77f223938f6700dee2a309886875a 593 SMART SM00257 427 471 1.6E-12 T 22-04-2016 IPR018392 LysM domain HRM2_RS17995 2cb77f223938f6700dee2a309886875a 593 SMART SM00257 495 538 2.5E-15 T 22-04-2016 IPR018392 LysM domain HRM2_RS17995 2cb77f223938f6700dee2a309886875a 593 SMART SM00257 549 593 7.8E-10 T 22-04-2016 IPR018392 LysM domain HRM2_RS17995 2cb77f223938f6700dee2a309886875a 593 SUPERFAMILY SSF53955 194 343 3.38E-36 T 22-04-2016 IPR023346 Lysozyme-like domain HRM2_RS17995 2cb77f223938f6700dee2a309886875a 593 Gene3D G3DSA:1.10.530.10 190 344 3.4E-42 T 22-04-2016 HRM2_RS17995 2cb77f223938f6700dee2a309886875a 593 PANTHER PTHR21666 164 537 1.3E-68 T 22-04-2016 HRM2_RS17995 2cb77f223938f6700dee2a309886875a 593 Pfam PF01464 Transglycosylase SLT domain 199 303 1.5E-23 T 22-04-2016 IPR008258 Transglycosylase SLT domain 1 HRM2_RS17995 2cb77f223938f6700dee2a309886875a 593 SUPERFAMILY SSF54106 549 592 2.49E-9 T 22-04-2016 IPR018392 LysM domain HRM2_RS03395 af470be4afbde19b66fb5a21d6c7f0f7 203 PANTHER PTHR19136:SF78 2 193 2.0E-33 T 22-04-2016 HRM2_RS03395 af470be4afbde19b66fb5a21d6c7f0f7 203 SUPERFAMILY SSF53448 1 189 1.26E-30 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS03395 af470be4afbde19b66fb5a21d6c7f0f7 203 Gene3D G3DSA:3.90.550.10 1 196 4.2E-35 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS03395 af470be4afbde19b66fb5a21d6c7f0f7 203 PANTHER PTHR19136 2 193 2.0E-33 T 22-04-2016 HRM2_RS03395 af470be4afbde19b66fb5a21d6c7f0f7 203 Pfam PF12804 MobA-like NTP transferase domain 5 164 8.8E-37 T 22-04-2016 IPR025877 MobA-like NTP transferase HRM2_RS01715 35025ce20da40f655e4425e3f59cc7e4 123 PANTHER PTHR30432 1 121 6.8E-16 T 22-04-2016 HRM2_RS01715 35025ce20da40f655e4425e3f59cc7e4 123 Gene3D G3DSA:1.10.10.10 9 113 2.9E-31 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS01715 35025ce20da40f655e4425e3f59cc7e4 123 SUPERFAMILY SSF46785 13 104 4.99E-24 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS01715 35025ce20da40f655e4425e3f59cc7e4 123 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 29 80 5.0E-16 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HRM2_RS13925 2a4c8509a40a9a5a9f56604b01f20fee 299 Gene3D G3DSA:1.20.58.180 205 286 2.9E-37 T 22-04-2016 HRM2_RS13925 2a4c8509a40a9a5a9f56604b01f20fee 299 Gene3D G3DSA:3.30.930.10 1 203 5.0E-105 T 22-04-2016 HRM2_RS13925 2a4c8509a40a9a5a9f56604b01f20fee 299 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 1 281 59.495 T 22-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HRM2_RS13925 2a4c8509a40a9a5a9f56604b01f20fee 299 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 241 257 8.707506E-65 T 22-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HRM2_RS13925 2a4c8509a40a9a5a9f56604b01f20fee 299 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 76 96 8.707506E-65 T 22-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HRM2_RS13925 2a4c8509a40a9a5a9f56604b01f20fee 299 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 133 153 8.707506E-65 T 22-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HRM2_RS13925 2a4c8509a40a9a5a9f56604b01f20fee 299 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 107 131 8.707506E-65 T 22-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HRM2_RS13925 2a4c8509a40a9a5a9f56604b01f20fee 299 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 55 70 8.707506E-65 T 22-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HRM2_RS13925 2a4c8509a40a9a5a9f56604b01f20fee 299 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 156 171 8.707506E-65 T 22-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HRM2_RS13925 2a4c8509a40a9a5a9f56604b01f20fee 299 PANTHER PTHR30075 1 288 1.0E-242 T 22-04-2016 HRM2_RS13925 2a4c8509a40a9a5a9f56604b01f20fee 299 SUPERFAMILY SSF55681 1 280 8.08E-134 T 22-04-2016 HRM2_RS13925 2a4c8509a40a9a5a9f56604b01f20fee 299 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 3 280 7.3E-152 T 22-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HRM2_RS13925 2a4c8509a40a9a5a9f56604b01f20fee 299 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 1 288 2.2E-156 T 22-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HRM2_RS04705 41ec4a4df70f69d883478b17ef228a84 80 PIRSF PIRSF006169 4 78 8.3E-27 T 22-04-2016 IPR010648 Uncharacterised protein family UPF0270 HRM2_RS04705 41ec4a4df70f69d883478b17ef228a84 80 Pfam PF06794 Uncharacterised protein family (UPF0270) 6 70 1.2E-27 T 22-04-2016 IPR010648 Uncharacterised protein family UPF0270 HRM2_RS04705 41ec4a4df70f69d883478b17ef228a84 80 SUPERFAMILY SSF118001 4 71 1.06E-24 T 22-04-2016 IPR010648 Uncharacterised protein family UPF0270 HRM2_RS04705 41ec4a4df70f69d883478b17ef228a84 80 Gene3D G3DSA:1.10.10.610 5 71 2.4E-27 T 22-04-2016 IPR010648 Uncharacterised protein family UPF0270 HRM2_RS04705 41ec4a4df70f69d883478b17ef228a84 80 ProDom PD026997 UPF0270 YHEU SO0879 3D-STRUCTURE LYASE PLU0398 YPO0179/Y3960/YP0178 ENOLASE HD0737 PSPTO1630 4 67 2.0E-14 T 22-04-2016 IPR010648 Uncharacterised protein family UPF0270 HRM2_RS01995 2c73a956d85368d12b05d9dd93adbc5c 398 Pfam PF09983 Uncharacterized protein conserved in bacteria C-term(DUF2220) 216 389 1.9E-53 T 22-04-2016 IPR024534 Domain of unknown function DUF2220 HRM2_RS01995 2c73a956d85368d12b05d9dd93adbc5c 398 PIRSF PIRSF028408 4 397 2.5E-78 T 22-04-2016 IPR014544 Uncharacterised conserved protein UCP028408 HRM2_RS01995 2c73a956d85368d12b05d9dd93adbc5c 398 Pfam PF11795 Uncharacterized protein conserved in bacteria N-term (DUF3322) 9 192 3.1E-58 T 22-04-2016 IPR024537 Domain of unknown function DUF3322 HRM2_RS04045 6e22de401ec7610eab43a54d0ea523e0 362 Gene3D G3DSA:3.90.226.10 185 351 4.7E-33 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS04045 6e22de401ec7610eab43a54d0ea523e0 362 Gene3D G3DSA:2.30.42.10 94 173 4.5E-15 T 22-04-2016 IPR001478 PDZ domain GO:0005515 HRM2_RS04045 6e22de401ec7610eab43a54d0ea523e0 362 PANTHER PTHR32060 70 346 1.5E-51 T 22-04-2016 HRM2_RS04045 6e22de401ec7610eab43a54d0ea523e0 362 SMART SM00245 150 347 1.3E-15 T 22-04-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 HRM2_RS04045 6e22de401ec7610eab43a54d0ea523e0 362 Pfam PF13180 PDZ domain 108 170 2.9E-6 T 22-04-2016 IPR001478 PDZ domain GO:0005515 HRM2_RS04045 6e22de401ec7610eab43a54d0ea523e0 362 SUPERFAMILY SSF52096 181 351 2.49E-38 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS04045 6e22de401ec7610eab43a54d0ea523e0 362 SUPERFAMILY SSF52096 40 111 2.49E-38 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS04045 6e22de401ec7610eab43a54d0ea523e0 362 Pfam PF03572 Peptidase family S41 190 344 4.9E-24 T 22-04-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 HRM2_RS04045 6e22de401ec7610eab43a54d0ea523e0 362 SUPERFAMILY SSF50156 110 178 2.38E-10 T 22-04-2016 IPR001478 PDZ domain GO:0005515 HRM2_RS04045 6e22de401ec7610eab43a54d0ea523e0 362 SMART SM00228 93 163 4.4E-6 T 22-04-2016 IPR001478 PDZ domain GO:0005515 HRM2_RS15880 aa4a3513c6ec7373fff29f791f240ba5 303 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 22-04-2016 IPR018253 DnaJ domain, conserved site HRM2_RS15880 aa4a3513c6ec7373fff29f791f240ba5 303 Pfam PF00226 DnaJ domain 5 67 4.2E-28 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS15880 aa4a3513c6ec7373fff29f791f240ba5 303 SMART SM00271 4 62 5.3E-29 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS15880 aa4a3513c6ec7373fff29f791f240ba5 303 Gene3D G3DSA:1.10.287.110 3 87 1.4E-34 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS15880 aa4a3513c6ec7373fff29f791f240ba5 303 PRINTS PR00625 DnaJ domain signature 25 40 1.2E-25 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS15880 aa4a3513c6ec7373fff29f791f240ba5 303 PRINTS PR00625 DnaJ domain signature 62 81 1.2E-25 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS15880 aa4a3513c6ec7373fff29f791f240ba5 303 PRINTS PR00625 DnaJ domain signature 42 62 1.2E-25 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS15880 aa4a3513c6ec7373fff29f791f240ba5 303 PRINTS PR00625 DnaJ domain signature 7 25 1.2E-25 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS15880 aa4a3513c6ec7373fff29f791f240ba5 303 SUPERFAMILY SSF49493 128 200 7.85E-15 T 22-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 HRM2_RS15880 aa4a3513c6ec7373fff29f791f240ba5 303 PANTHER PTHR24078:SF190 3 300 5.5E-82 T 22-04-2016 HRM2_RS15880 aa4a3513c6ec7373fff29f791f240ba5 303 SUPERFAMILY SSF49493 209 295 1.96E-22 T 22-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 HRM2_RS15880 aa4a3513c6ec7373fff29f791f240ba5 303 Gene3D G3DSA:2.60.260.20 209 285 9.1E-20 T 22-04-2016 HRM2_RS15880 aa4a3513c6ec7373fff29f791f240ba5 303 SUPERFAMILY SSF46565 2 109 6.67E-33 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS15880 aa4a3513c6ec7373fff29f791f240ba5 303 PANTHER PTHR24078 3 300 5.5E-82 T 22-04-2016 HRM2_RS15880 aa4a3513c6ec7373fff29f791f240ba5 303 Pfam PF01556 DnaJ C terminal domain 135 284 3.6E-35 T 22-04-2016 IPR002939 Chaperone DnaJ, C-terminal HRM2_RS15880 aa4a3513c6ec7373fff29f791f240ba5 303 Gene3D G3DSA:2.60.260.20 102 200 3.8E-18 T 22-04-2016 HRM2_RS04290 c64e9f4758c448067080f73fafd87b54 379 SUPERFAMILY SSF51316 240 379 4.6E-60 T 22-04-2016 IPR011057 Mss4-like HRM2_RS04290 c64e9f4758c448067080f73fafd87b54 379 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 238 364 36.456 T 22-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 HRM2_RS04290 c64e9f4758c448067080f73fafd87b54 379 Pfam PF01625 Peptide methionine sulfoxide reductase 48 198 3.8E-58 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 HRM2_RS04290 c64e9f4758c448067080f73fafd87b54 379 PANTHER PTHR10173:SF31 1 192 1.4E-89 T 22-04-2016 HRM2_RS04290 c64e9f4758c448067080f73fafd87b54 379 PANTHER PTHR10173:SF31 343 379 1.4E-89 T 22-04-2016 HRM2_RS04290 c64e9f4758c448067080f73fafd87b54 379 PANTHER PTHR10173 1 192 1.4E-89 T 22-04-2016 IPR028427 Peptide methionine sulfoxide reductase GO:0006979|GO:0016671|GO:0030091 HRM2_RS04290 c64e9f4758c448067080f73fafd87b54 379 PANTHER PTHR10173 343 379 1.4E-89 T 22-04-2016 IPR028427 Peptide methionine sulfoxide reductase GO:0006979|GO:0016671|GO:0030091 HRM2_RS04290 c64e9f4758c448067080f73fafd87b54 379 Gene3D G3DSA:2.170.150.20 237 378 1.8E-60 T 22-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 HRM2_RS04290 c64e9f4758c448067080f73fafd87b54 379 Pfam PF01641 SelR domain 244 363 2.9E-48 T 22-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 HRM2_RS04290 c64e9f4758c448067080f73fafd87b54 379 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 45 204 36.175 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 HRM2_RS04290 c64e9f4758c448067080f73fafd87b54 379 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 47 197 1.4E-58 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 HRM2_RS04290 c64e9f4758c448067080f73fafd87b54 379 Gene3D G3DSA:3.30.1060.10 16 197 3.0E-69 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 HRM2_RS04290 c64e9f4758c448067080f73fafd87b54 379 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 239 372 8.1E-63 T 22-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 HRM2_RS04290 c64e9f4758c448067080f73fafd87b54 379 SUPERFAMILY SSF55068 20 210 3.79E-73 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 HRM2_RS00695 b8c7ff721c4eef457e7474e62cb56950 165 PANTHER PTHR10173 4 103 2.7E-28 T 22-04-2016 IPR028427 Peptide methionine sulfoxide reductase GO:0006979|GO:0016671|GO:0030091 HRM2_RS00695 b8c7ff721c4eef457e7474e62cb56950 165 Gene3D G3DSA:3.30.1060.10 3 104 1.2E-29 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 HRM2_RS00695 b8c7ff721c4eef457e7474e62cb56950 165 SUPERFAMILY SSF55068 3 104 1.11E-30 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 HRM2_RS00695 b8c7ff721c4eef457e7474e62cb56950 165 PANTHER PTHR10173:SF6 4 103 2.7E-28 T 22-04-2016 HRM2_RS00695 b8c7ff721c4eef457e7474e62cb56950 165 Pfam PF01625 Peptide methionine sulfoxide reductase 4 103 2.4E-24 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 HRM2_RS23540 74c148bae868e2c35c15acca006b81cc 331 Gene3D G3DSA:3.40.50.10330 86 130 3.5E-4 T 22-04-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 HRM2_RS23540 74c148bae868e2c35c15acca006b81cc 331 PIRSF PIRSF018567 1 329 9.8E-102 T 22-04-2016 IPR011391 Acetoin catabolism kinase AcoX UniPathway: UPA00040 HRM2_RS23540 74c148bae868e2c35c15acca006b81cc 331 Pfam PF01513 ATP-NAD kinase 3 164 1.7E-12 T 22-04-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 HRM2_RS23540 74c148bae868e2c35c15acca006b81cc 331 SUPERFAMILY SSF111331 79 311 4.02E-9 T 22-04-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain HRM2_RS07675 69df3c5136d3f952a278f00d576770a6 405 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 294 398 4.2E-20 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS07675 69df3c5136d3f952a278f00d576770a6 405 SMART SM00387 292 400 3.4E-28 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS07675 69df3c5136d3f952a278f00d576770a6 405 PANTHER PTHR24423 27 397 1.7E-78 T 22-04-2016 HRM2_RS07675 69df3c5136d3f952a278f00d576770a6 405 SUPERFAMILY SSF47384 161 244 1.71E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS07675 69df3c5136d3f952a278f00d576770a6 405 Pfam PF00512 His Kinase A (phospho-acceptor) domain 171 244 6.1E-15 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS07675 69df3c5136d3f952a278f00d576770a6 405 Gene3D G3DSA:3.30.565.10 251 397 3.0E-41 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS07675 69df3c5136d3f952a278f00d576770a6 405 SMART SM00388 169 249 2.1E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS07675 69df3c5136d3f952a278f00d576770a6 405 SUPERFAMILY SSF55874 248 397 8.91E-41 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS07675 69df3c5136d3f952a278f00d576770a6 405 Gene3D G3DSA:3.30.450.20 31 152 5.2E-13 T 22-04-2016 HRM2_RS07675 69df3c5136d3f952a278f00d576770a6 405 PRINTS PR00344 Bacterial sensor protein C-terminal signature 347 357 3.1E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS07675 69df3c5136d3f952a278f00d576770a6 405 PRINTS PR00344 Bacterial sensor protein C-terminal signature 384 397 3.1E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS07675 69df3c5136d3f952a278f00d576770a6 405 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 378 3.1E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS07675 69df3c5136d3f952a278f00d576770a6 405 PRINTS PR00344 Bacterial sensor protein C-terminal signature 329 343 3.1E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS07675 69df3c5136d3f952a278f00d576770a6 405 Gene3D G3DSA:1.10.287.130 165 244 7.9E-13 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS07675 69df3c5136d3f952a278f00d576770a6 405 Pfam PF13426 PAS domain 54 152 1.9E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS07675 69df3c5136d3f952a278f00d576770a6 405 SUPERFAMILY SSF55785 29 152 3.56E-12 T 22-04-2016 IPR000014 PAS domain HRM2_RS08520 5377a1ba1ab1c616de88078f0d94e406 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 11 184 9.3E-68 T 22-04-2016 IPR002661 Ribosome recycling factor GO:0006412 HRM2_RS08520 5377a1ba1ab1c616de88078f0d94e406 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 26.346 T 22-04-2016 IPR002661 Ribosome recycling factor GO:0006412 HRM2_RS08520 5377a1ba1ab1c616de88078f0d94e406 185 Pfam PF01765 Ribosome recycling factor 20 183 1.0E-61 T 22-04-2016 IPR023584 Ribosome recycling factor domain HRM2_RS08520 5377a1ba1ab1c616de88078f0d94e406 185 Gene3D G3DSA:1.10.132.20 66 184 1.0E-41 T 22-04-2016 IPR023584 Ribosome recycling factor domain HRM2_RS08520 5377a1ba1ab1c616de88078f0d94e406 185 SUPERFAMILY SSF55194 1 184 1.7E-68 T 22-04-2016 IPR023584 Ribosome recycling factor domain HRM2_RS08520 5377a1ba1ab1c616de88078f0d94e406 185 PANTHER PTHR20982 1 185 6.5E-75 T 22-04-2016 IPR002661 Ribosome recycling factor GO:0006412 HRM2_RS25640 58188225f84f285d3c150a32749f3f54 363 PANTHER PTHR39431 155 334 4.9E-14 T 22-04-2016 HRM2_RS01760 78812ab42f76386c425637271904df32 374 SUPERFAMILY SSF51395 2 336 1.47E-99 T 22-04-2016 HRM2_RS01760 78812ab42f76386c425637271904df32 374 PANTHER PTHR22893 2 339 2.0E-98 T 22-04-2016 HRM2_RS01760 78812ab42f76386c425637271904df32 374 Gene3D G3DSA:3.20.20.70 1 364 8.3E-110 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS01760 78812ab42f76386c425637271904df32 374 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 330 2.6E-65 T 22-04-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 HRM2_RS19180 f7edf2fd8221bbf3f4029f72d083e3d8 372 PANTHER PTHR11751:SF388 51 370 4.3E-68 T 22-04-2016 HRM2_RS19180 f7edf2fd8221bbf3f4029f72d083e3d8 372 SUPERFAMILY SSF53383 48 369 5.39E-68 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS19180 f7edf2fd8221bbf3f4029f72d083e3d8 372 PANTHER PTHR11751 51 370 4.3E-68 T 22-04-2016 HRM2_RS19180 f7edf2fd8221bbf3f4029f72d083e3d8 372 Gene3D G3DSA:3.40.640.10 50 237 1.2E-49 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS19180 f7edf2fd8221bbf3f4029f72d083e3d8 372 Gene3D G3DSA:3.90.1150.10 238 369 1.2E-15 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS19180 f7edf2fd8221bbf3f4029f72d083e3d8 372 Pfam PF00155 Aminotransferase class I and II 50 354 2.8E-39 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HRM2_RS14595 8159bbb183ced25a3b9e40c24f3e424a 324 PIRSF PIRSF002849 1 324 2.1E-132 T 22-04-2016 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted HRM2_RS14595 8159bbb183ced25a3b9e40c24f3e424a 324 SUPERFAMILY SSF52540 5 296 3.37E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14595 8159bbb183ced25a3b9e40c24f3e424a 324 SMART SM00382 42 183 0.0062 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS14595 8159bbb183ced25a3b9e40c24f3e424a 324 Gene3D G3DSA:3.40.50.300 27 191 1.8E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14595 8159bbb183ced25a3b9e40c24f3e424a 324 PANTHER PTHR11603 5 324 8.6E-139 T 22-04-2016 HRM2_RS14595 8159bbb183ced25a3b9e40c24f3e424a 324 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 45 175 9.1E-65 T 22-04-2016 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 HRM2_RS14595 8159bbb183ced25a3b9e40c24f3e424a 324 PANTHER PTHR11603:SF148 5 324 8.6E-139 T 22-04-2016 HRM2_RS14595 8159bbb183ced25a3b9e40c24f3e424a 324 Gene3D G3DSA:1.10.8.300 205 319 1.6E-41 T 22-04-2016 HRM2_RS07785 86625e0d7860dd88f499a2fea644d4c5 222 Gene3D G3DSA:1.10.10.10 2 72 1.6E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS07785 86625e0d7860dd88f499a2fea644d4c5 222 SMART SM00895 81 207 5.9E-11 T 22-04-2016 IPR011711 GntR, C-terminal HRM2_RS07785 86625e0d7860dd88f499a2fea644d4c5 222 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 6.1E-6 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS07785 86625e0d7860dd88f499a2fea644d4c5 222 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 6.1E-6 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS07785 86625e0d7860dd88f499a2fea644d4c5 222 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 71 4.2E-17 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS07785 86625e0d7860dd88f499a2fea644d4c5 222 SUPERFAMILY SSF46785 2 75 2.51E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS07785 86625e0d7860dd88f499a2fea644d4c5 222 PANTHER PTHR11751:SF426 10 97 3.2E-21 T 22-04-2016 HRM2_RS07785 86625e0d7860dd88f499a2fea644d4c5 222 SMART SM00345 13 71 1.3E-16 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS07785 86625e0d7860dd88f499a2fea644d4c5 222 SUPERFAMILY SSF48008 78 212 6.28E-17 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS07785 86625e0d7860dd88f499a2fea644d4c5 222 Gene3D G3DSA:1.20.120.530 74 214 2.2E-20 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS07785 86625e0d7860dd88f499a2fea644d4c5 222 Pfam PF07729 FCD domain 87 205 1.0E-14 T 22-04-2016 IPR011711 GntR, C-terminal HRM2_RS07785 86625e0d7860dd88f499a2fea644d4c5 222 PANTHER PTHR11751 10 97 3.2E-21 T 22-04-2016 HRM2_RS19920 ad8c70c171e223c2f913889469154b5b 192 SUPERFAMILY SSF55120 10 184 1.54E-41 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS19920 ad8c70c171e223c2f913889469154b5b 192 Pfam PF00849 RNA pseudouridylate synthase 8 124 6.8E-26 T 22-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS19920 ad8c70c171e223c2f913889469154b5b 192 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 15 29 - T 22-04-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS19920 ad8c70c171e223c2f913889469154b5b 192 PANTHER PTHR11079:SF84 15 188 2.6E-32 T 22-04-2016 HRM2_RS19920 ad8c70c171e223c2f913889469154b5b 192 PANTHER PTHR11079 15 188 2.6E-32 T 22-04-2016 HRM2_RS02190 19208fb732182308104141305a91bb4a 709 Gene3D G3DSA:3.40.50.720 2 131 8.6E-38 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS02190 19208fb732182308104141305a91bb4a 709 Pfam PF13380 CoA binding domain 9 134 3.5E-24 T 22-04-2016 IPR003781 CoA-binding GO:0048037 HRM2_RS02190 19208fb732182308104141305a91bb4a 709 PANTHER PTHR11117 31 709 3.0E-194 T 22-04-2016 HRM2_RS02190 19208fb732182308104141305a91bb4a 709 SUPERFAMILY SSF56059 496 708 3.33E-32 T 22-04-2016 HRM2_RS02190 19208fb732182308104141305a91bb4a 709 SUPERFAMILY SSF52210 132 290 4.19E-33 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS02190 19208fb732182308104141305a91bb4a 709 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 150 288 4.8E-45 T 22-04-2016 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain HRM2_RS02190 19208fb732182308104141305a91bb4a 709 SMART SM00881 5 100 4.3E-31 T 22-04-2016 IPR003781 CoA-binding GO:0048037 HRM2_RS02190 19208fb732182308104141305a91bb4a 709 Gene3D G3DSA:3.40.50.261 132 285 6.5E-31 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS02190 19208fb732182308104141305a91bb4a 709 Pfam PF13549 ATP-grasp domain 488 708 7.2E-72 T 22-04-2016 HRM2_RS02190 19208fb732182308104141305a91bb4a 709 SUPERFAMILY SSF51735 2 130 5.25E-34 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS02190 19208fb732182308104141305a91bb4a 709 Gene3D G3DSA:3.40.50.261 286 418 1.2E-7 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS02190 19208fb732182308104141305a91bb4a 709 SUPERFAMILY SSF52210 296 460 1.57E-27 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS02190 19208fb732182308104141305a91bb4a 709 PANTHER PTHR11117:SF8 31 709 3.0E-194 T 22-04-2016 HRM2_RS11195 034ce6c5d543994d556ef1ae43eea6f9 174 ProSitePatterns PS00352 'Cold-shock' domain signature. 16 35 - T 22-04-2016 IPR019844 Cold-shock conserved site HRM2_RS11195 034ce6c5d543994d556ef1ae43eea6f9 174 SUPERFAMILY SSF50249 2 68 7.5E-12 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS11195 034ce6c5d543994d556ef1ae43eea6f9 174 SMART SM00357 4 68 5.5E-4 T 22-04-2016 IPR011129 Cold shock protein GO:0003676 HRM2_RS11195 034ce6c5d543994d556ef1ae43eea6f9 174 Pfam PF05901 Excalibur calcium-binding domain 136 169 1.7E-10 T 22-04-2016 IPR008613 Excalibur calcium-binding domain HRM2_RS11195 034ce6c5d543994d556ef1ae43eea6f9 174 Pfam PF00313 'Cold-shock' DNA-binding domain 6 64 1.9E-7 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HRM2_RS11195 034ce6c5d543994d556ef1ae43eea6f9 174 Gene3D G3DSA:2.40.50.140 3 72 1.1E-16 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS04880 63f62fd8722a4775e8961ab5d2a658b7 621 Pfam PF00989 PAS fold 339 380 1.6E-7 T 22-04-2016 IPR013767 PAS fold GO:0006355 HRM2_RS04880 63f62fd8722a4775e8961ab5d2a658b7 621 Pfam PF03600 Citrate transporter 50 566 5.4E-73 T 22-04-2016 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 HRM2_RS04880 63f62fd8722a4775e8961ab5d2a658b7 621 SMART SM00091 338 405 0.0044 T 22-04-2016 IPR000014 PAS domain HRM2_RS04880 63f62fd8722a4775e8961ab5d2a658b7 621 Gene3D G3DSA:3.30.450.20 336 472 1.2E-20 T 22-04-2016 HRM2_RS04880 63f62fd8722a4775e8961ab5d2a658b7 621 PANTHER PTHR10283 398 424 3.6E-135 T 22-04-2016 HRM2_RS04880 63f62fd8722a4775e8961ab5d2a658b7 621 PANTHER PTHR10283 6 309 3.6E-135 T 22-04-2016 HRM2_RS04880 63f62fd8722a4775e8961ab5d2a658b7 621 PANTHER PTHR10283 469 621 3.6E-135 T 22-04-2016 HRM2_RS04880 63f62fd8722a4775e8961ab5d2a658b7 621 SUPERFAMILY SSF55785 341 463 2.09E-10 T 22-04-2016 IPR000014 PAS domain HRM2_RS04880 63f62fd8722a4775e8961ab5d2a658b7 621 PANTHER PTHR10283:SF91 398 424 3.6E-135 T 22-04-2016 HRM2_RS04880 63f62fd8722a4775e8961ab5d2a658b7 621 PANTHER PTHR10283:SF91 6 309 3.6E-135 T 22-04-2016 HRM2_RS04880 63f62fd8722a4775e8961ab5d2a658b7 621 PANTHER PTHR10283:SF91 469 621 3.6E-135 T 22-04-2016 HRM2_RS11075 e374af0fe18f3907fec3bb1e9d341670 314 PIRSF PIRSF000310 7 314 5.4E-127 T 22-04-2016 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 HRM2_RS11075 e374af0fe18f3907fec3bb1e9d341670 314 SUPERFAMILY SSF56770 56 312 1.96E-87 T 22-04-2016 HRM2_RS11075 e374af0fe18f3907fec3bb1e9d341670 314 TIGRFAM TIGR00391 hydA: hydrogenase (NiFe) small subunit (hydA) 4 312 1.0E-112 T 22-04-2016 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 HRM2_RS11075 e374af0fe18f3907fec3bb1e9d341670 314 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 285 298 5.9E-57 T 22-04-2016 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 HRM2_RS11075 e374af0fe18f3907fec3bb1e9d341670 314 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 190 213 5.9E-57 T 22-04-2016 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 HRM2_RS11075 e374af0fe18f3907fec3bb1e9d341670 314 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 233 251 5.9E-57 T 22-04-2016 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 HRM2_RS11075 e374af0fe18f3907fec3bb1e9d341670 314 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 162 186 5.9E-57 T 22-04-2016 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 HRM2_RS11075 e374af0fe18f3907fec3bb1e9d341670 314 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 119 142 5.9E-57 T 22-04-2016 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 HRM2_RS11075 e374af0fe18f3907fec3bb1e9d341670 314 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 52 74 5.9E-57 T 22-04-2016 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 HRM2_RS11075 e374af0fe18f3907fec3bb1e9d341670 314 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 257 283 5.9E-57 T 22-04-2016 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 HRM2_RS11075 e374af0fe18f3907fec3bb1e9d341670 314 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 215 232 5.9E-57 T 22-04-2016 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 HRM2_RS11075 e374af0fe18f3907fec3bb1e9d341670 314 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 67 209 2.3E-29 T 22-04-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 HRM2_RS11075 e374af0fe18f3907fec3bb1e9d341670 314 PANTHER PTHR30013 3 314 2.1E-145 T 22-04-2016 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 HRM2_RS11075 e374af0fe18f3907fec3bb1e9d341670 314 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 18 45 6.2E-7 T 22-04-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal HRM2_RS11075 e374af0fe18f3907fec3bb1e9d341670 314 PANTHER PTHR30013:SF7 3 314 2.1E-145 T 22-04-2016 HRM2_RS11075 e374af0fe18f3907fec3bb1e9d341670 314 Gene3D G3DSA:3.40.50.700 56 226 4.2E-51 T 22-04-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 HRM2_RS11075 e374af0fe18f3907fec3bb1e9d341670 314 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 228 311 1.1E-34 T 22-04-2016 IPR027394 Cytochrome-c3 hydrogenase, C-terminal HRM2_RS11075 e374af0fe18f3907fec3bb1e9d341670 314 Gene3D G3DSA:4.10.480.10 228 312 1.7E-38 T 22-04-2016 IPR027394 Cytochrome-c3 hydrogenase, C-terminal HRM2_RS20285 72d164c7aea299ac08d0c0f011742414 282 Gene3D G3DSA:3.40.50.970 13 262 1.6E-78 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS20285 72d164c7aea299ac08d0c0f011742414 282 PANTHER PTHR18968:SF40 7 278 2.2E-128 T 22-04-2016 HRM2_RS20285 72d164c7aea299ac08d0c0f011742414 282 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 199 263 1.4E-27 T 22-04-2016 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal HRM2_RS20285 72d164c7aea299ac08d0c0f011742414 282 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 53 195 3.7E-30 T 22-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HRM2_RS20285 72d164c7aea299ac08d0c0f011742414 282 SUPERFAMILY SSF52518 11 263 2.24E-77 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS20285 72d164c7aea299ac08d0c0f011742414 282 PANTHER PTHR18968 7 278 2.2E-128 T 22-04-2016 HRM2_RS20285 72d164c7aea299ac08d0c0f011742414 282 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 14 265 4.2E-111 T 22-04-2016 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate HRM2_RS04725 9dbcc7ac2dec6c42bf3d33bfae983133 156 SUPERFAMILY SSF46785 37 156 8.96E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS04725 9dbcc7ac2dec6c42bf3d33bfae983133 156 Gene3D G3DSA:1.10.10.10 31 156 4.9E-25 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS04725 9dbcc7ac2dec6c42bf3d33bfae983133 156 SMART SM00347 46 146 1.6E-16 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS04725 9dbcc7ac2dec6c42bf3d33bfae983133 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 86 5.0E-8 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS04725 9dbcc7ac2dec6c42bf3d33bfae983133 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 102 5.0E-8 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS04725 9dbcc7ac2dec6c42bf3d33bfae983133 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 106 122 5.0E-8 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS04725 9dbcc7ac2dec6c42bf3d33bfae983133 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 136 156 5.0E-8 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS04725 9dbcc7ac2dec6c42bf3d33bfae983133 156 Pfam PF01047 MarR family 54 110 1.9E-12 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS04725 9dbcc7ac2dec6c42bf3d33bfae983133 156 PANTHER PTHR33164 53 156 9.2E-16 T 22-04-2016 HRM2_RS15520 2cf0c91af5d559937693872368f2f865 476 SUPERFAMILY SSF89095 297 403 3.92E-33 T 22-04-2016 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 HRM2_RS15520 2cf0c91af5d559937693872368f2f865 476 SUPERFAMILY SSF55931 4 296 1.96E-127 T 22-04-2016 HRM2_RS15520 2cf0c91af5d559937693872368f2f865 476 SMART SM00845 328 475 2.5E-73 T 22-04-2016 IPR018027 Asn/Gln amidotransferase GO:0016884 HRM2_RS15520 2cf0c91af5d559937693872368f2f865 476 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 476 40.047 T 22-04-2016 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 HRM2_RS15520 2cf0c91af5d559937693872368f2f865 476 Gene3D G3DSA:1.10.10.410 419 476 1.6E-7 T 22-04-2016 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal HRM2_RS15520 2cf0c91af5d559937693872368f2f865 476 Pfam PF02637 GatB domain 328 475 3.6E-53 T 22-04-2016 IPR018027 Asn/Gln amidotransferase GO:0016884 HRM2_RS15520 2cf0c91af5d559937693872368f2f865 476 Pfam PF02934 GatB/GatE catalytic domain 6 289 1.4E-119 T 22-04-2016 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 HRM2_RS15520 2cf0c91af5d559937693872368f2f865 476 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 475 1.2E-188 T 22-04-2016 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 HRM2_RS15520 2cf0c91af5d559937693872368f2f865 476 PANTHER PTHR11659 2 476 3.1E-266 T 22-04-2016 IPR017959 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E GO:0016884 HRM2_RS15520 2cf0c91af5d559937693872368f2f865 476 PANTHER PTHR11659:SF0 2 476 3.1E-266 T 22-04-2016 HRM2_RS15520 2cf0c91af5d559937693872368f2f865 476 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 144 158 - T 22-04-2016 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 HRM2_RS21030 c8fd2eea3e7156a344c015b703375bf2 675 PANTHER PTHR30441 1 633 3.6E-45 T 22-04-2016 HRM2_RS21030 c8fd2eea3e7156a344c015b703375bf2 675 Pfam PF05170 AsmA family 1 182 1.8E-28 T 22-04-2016 IPR007844 AsmA HRM2_RS21030 c8fd2eea3e7156a344c015b703375bf2 675 Pfam PF05170 AsmA family 393 557 1.5E-21 T 22-04-2016 IPR007844 AsmA HRM2_RS02845 6aad0cefff34089f299c1032fcf27eb7 318 SUPERFAMILY SSF56059 243 287 4.95E-22 T 22-04-2016 HRM2_RS02845 6aad0cefff34089f299c1032fcf27eb7 318 SUPERFAMILY SSF56059 85 210 4.95E-22 T 22-04-2016 HRM2_RS02845 6aad0cefff34089f299c1032fcf27eb7 318 PANTHER PTHR21621 1 203 8.1E-28 T 22-04-2016 HRM2_RS02845 6aad0cefff34089f299c1032fcf27eb7 318 PANTHER PTHR21621 225 318 8.1E-28 T 22-04-2016 HRM2_RS02845 6aad0cefff34089f299c1032fcf27eb7 318 Gene3D G3DSA:3.30.470.20 97 284 2.6E-14 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS02845 6aad0cefff34089f299c1032fcf27eb7 318 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 105 161 2.8E-5 T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HRM2_RS02845 6aad0cefff34089f299c1032fcf27eb7 318 PANTHER PTHR21621:SF0 1 203 8.1E-28 T 22-04-2016 HRM2_RS02845 6aad0cefff34089f299c1032fcf27eb7 318 PANTHER PTHR21621:SF0 225 318 8.1E-28 T 22-04-2016 HRM2_RS02845 6aad0cefff34089f299c1032fcf27eb7 318 Gene3D G3DSA:3.40.50.20 2 96 7.5E-7 T 22-04-2016 IPR016185 Pre-ATP-grasp domain HRM2_RS05265 8e597e43f27a6232fb860cbb5d8fd62e 78 PANTHER PTHR24960:SF52 6 66 1.1E-14 T 22-04-2016 HRM2_RS05265 8e597e43f27a6232fb860cbb5d8fd62e 78 Pfam PF12838 4Fe-4S dicluster domain 11 60 2.2E-9 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS05265 8e597e43f27a6232fb860cbb5d8fd62e 78 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 12 23 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS05265 8e597e43f27a6232fb860cbb5d8fd62e 78 PANTHER PTHR24960 6 66 1.1E-14 T 22-04-2016 HRM2_RS05265 8e597e43f27a6232fb860cbb5d8fd62e 78 SUPERFAMILY SSF54862 4 69 2.9E-15 T 22-04-2016 HRM2_RS05265 8e597e43f27a6232fb860cbb5d8fd62e 78 Gene3D G3DSA:3.30.70.20 6 72 4.3E-15 T 22-04-2016 HRM2_RS02960 013bab5aa50a08ae3e8a75d2b2ec6cd7 225 Pfam PF05908 Poly-gamma-glutamate hydrolase 4 189 1.4E-65 T 22-04-2016 IPR008585 Poly-gamma-glutamate hydrolase HRM2_RS02275 f66186dcecb132f0a3901fdf6b11eb61 330 Pfam PF01409 tRNA synthetases class II core domain (F) 85 330 2.0E-104 T 22-04-2016 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 HRM2_RS02275 f66186dcecb132f0a3901fdf6b11eb61 330 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 5 330 45.183 T 22-04-2016 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 HRM2_RS02275 f66186dcecb132f0a3901fdf6b11eb61 330 SUPERFAMILY SSF55681 85 330 9.21E-83 T 22-04-2016 HRM2_RS02275 f66186dcecb132f0a3901fdf6b11eb61 330 PANTHER PTHR11538 85 330 5.1E-104 T 22-04-2016 HRM2_RS02275 f66186dcecb132f0a3901fdf6b11eb61 330 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 19 75 1.1E-13 T 22-04-2016 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 HRM2_RS02275 f66186dcecb132f0a3901fdf6b11eb61 330 Gene3D G3DSA:3.30.930.10 6 330 3.9E-119 T 22-04-2016 HRM2_RS02275 f66186dcecb132f0a3901fdf6b11eb61 330 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 36 330 3.1E-102 T 22-04-2016 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 HRM2_RS02275 f66186dcecb132f0a3901fdf6b11eb61 330 SUPERFAMILY SSF46589 11 92 9.42E-12 T 22-04-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 HRM2_RS02270 fbd09d46e4ef9c17a622c6af9bd77323 116 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 111 6.7E-46 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 HRM2_RS02270 fbd09d46e4ef9c17a622c6af9bd77323 116 PANTHER PTHR10986 1 116 1.1E-58 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 HRM2_RS02270 fbd09d46e4ef9c17a622c6af9bd77323 116 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 1 114 29.67 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 HRM2_RS02270 fbd09d46e4ef9c17a622c6af9bd77323 116 Gene3D G3DSA:1.10.1900.20 54 115 9.0E-28 T 22-04-2016 HRM2_RS02270 fbd09d46e4ef9c17a622c6af9bd77323 116 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 19 71 2.0E-9 T 22-04-2016 HRM2_RS02270 fbd09d46e4ef9c17a622c6af9bd77323 116 PANTHER PTHR10986:SF12 1 116 1.1E-58 T 22-04-2016 HRM2_RS02270 fbd09d46e4ef9c17a622c6af9bd77323 116 Pfam PF00453 Ribosomal protein L20 2 108 4.1E-47 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 HRM2_RS02270 fbd09d46e4ef9c17a622c6af9bd77323 116 ProSitePatterns PS00937 Ribosomal protein L20 signature. 53 69 - T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 HRM2_RS02270 fbd09d46e4ef9c17a622c6af9bd77323 116 PRINTS PR00062 Ribosomal protein L20 signature 11 40 4.8E-41 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 HRM2_RS02270 fbd09d46e4ef9c17a622c6af9bd77323 116 PRINTS PR00062 Ribosomal protein L20 signature 74 100 4.8E-41 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 HRM2_RS02270 fbd09d46e4ef9c17a622c6af9bd77323 116 PRINTS PR00062 Ribosomal protein L20 signature 41 70 4.8E-41 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 HRM2_RS02270 fbd09d46e4ef9c17a622c6af9bd77323 116 SUPERFAMILY SSF74731 1 112 1.2E-46 T 22-04-2016 HRM2_RS09090 b1d72a64c8ecc95ff6420a8a5505856c 62 Gene3D G3DSA:1.10.150.130 11 61 6.0E-5 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal HRM2_RS09090 b1d72a64c8ecc95ff6420a8a5505856c 62 SUPERFAMILY SSF56349 12 61 6.36E-5 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HRM2_RS15940 e28a03d6dc7cd9f0e297f682af85d4a9 167 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 31 150 2.2E-15 T 22-04-2016 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|UniPathway: UPA00028 HRM2_RS15940 e28a03d6dc7cd9f0e297f682af85d4a9 167 Gene3D G3DSA:1.10.1040.10 29 152 1.2E-19 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HRM2_RS15940 e28a03d6dc7cd9f0e297f682af85d4a9 167 SUPERFAMILY SSF48179 33 150 1.6E-12 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HRM2_RS00115 00872366ee9baf41f2ffe7c99454ccec 1102 SUPERFAMILY SSF48452 627 782 9.67E-5 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS00115 00872366ee9baf41f2ffe7c99454ccec 1102 Gene3D G3DSA:1.25.40.10 699 770 9.4E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS00115 00872366ee9baf41f2ffe7c99454ccec 1102 Gene3D G3DSA:1.25.40.10 483 613 9.4E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS00115 00872366ee9baf41f2ffe7c99454ccec 1102 Pfam PF03704 Bacterial transcriptional activator domain 955 1100 8.1E-24 T 22-04-2016 IPR005158 Bacterial transcriptional activator domain HRM2_RS00115 00872366ee9baf41f2ffe7c99454ccec 1102 Gene3D G3DSA:1.25.40.10 954 1077 1.9E-13 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS00115 00872366ee9baf41f2ffe7c99454ccec 1102 SUPERFAMILY SSF52540 17 255 1.82E-9 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00115 00872366ee9baf41f2ffe7c99454ccec 1102 SUPERFAMILY SSF48452 954 1099 3.21E-27 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS00115 00872366ee9baf41f2ffe7c99454ccec 1102 SMART SM00862 869 938 0.0089 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HRM2_RS00115 00872366ee9baf41f2ffe7c99454ccec 1102 SMART SM01043 955 1100 2.6E-33 T 22-04-2016 IPR005158 Bacterial transcriptional activator domain HRM2_RS00115 00872366ee9baf41f2ffe7c99454ccec 1102 Pfam PF13191 AAA ATPase domain 19 168 1.4E-9 T 22-04-2016 HRM2_RS00115 00872366ee9baf41f2ffe7c99454ccec 1102 PANTHER PTHR35807 756 1100 1.2E-34 T 22-04-2016 HRM2_RS00115 00872366ee9baf41f2ffe7c99454ccec 1102 PANTHER PTHR35807 195 719 1.2E-34 T 22-04-2016 HRM2_RS00115 00872366ee9baf41f2ffe7c99454ccec 1102 SUPERFAMILY SSF46894 851 933 4.59E-8 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HRM2_RS25105 8a2c011660557ba533b22114691db83a 567 SMART SM01182 151 176 1600.0 T 22-04-2016 IPR018940 Elongation factor 1 beta central acidic region, eukaryote Reactome: REACT_17015|Reactome: REACT_71 HRM2_RS25105 8a2c011660557ba533b22114691db83a 567 SMART SM01182 125 150 2500.0 T 22-04-2016 IPR018940 Elongation factor 1 beta central acidic region, eukaryote Reactome: REACT_17015|Reactome: REACT_71 HRM2_RS25105 8a2c011660557ba533b22114691db83a 567 SMART SM01182 203 228 2500.0 T 22-04-2016 IPR018940 Elongation factor 1 beta central acidic region, eukaryote Reactome: REACT_17015|Reactome: REACT_71 HRM2_RS25105 8a2c011660557ba533b22114691db83a 567 SMART SM01182 281 306 2500.0 T 22-04-2016 IPR018940 Elongation factor 1 beta central acidic region, eukaryote Reactome: REACT_17015|Reactome: REACT_71 HRM2_RS25105 8a2c011660557ba533b22114691db83a 567 SMART SM01182 177 202 2500.0 T 22-04-2016 IPR018940 Elongation factor 1 beta central acidic region, eukaryote Reactome: REACT_17015|Reactome: REACT_71 HRM2_RS25105 8a2c011660557ba533b22114691db83a 567 SMART SM01182 255 280 2500.0 T 22-04-2016 IPR018940 Elongation factor 1 beta central acidic region, eukaryote Reactome: REACT_17015|Reactome: REACT_71 HRM2_RS25105 8a2c011660557ba533b22114691db83a 567 SMART SM01182 47 72 1300.0 T 22-04-2016 IPR018940 Elongation factor 1 beta central acidic region, eukaryote Reactome: REACT_17015|Reactome: REACT_71 HRM2_RS25105 8a2c011660557ba533b22114691db83a 567 SMART SM01182 99 124 2500.0 T 22-04-2016 IPR018940 Elongation factor 1 beta central acidic region, eukaryote Reactome: REACT_17015|Reactome: REACT_71 HRM2_RS25105 8a2c011660557ba533b22114691db83a 567 SMART SM01182 73 98 2500.0 T 22-04-2016 IPR018940 Elongation factor 1 beta central acidic region, eukaryote Reactome: REACT_17015|Reactome: REACT_71 HRM2_RS25105 8a2c011660557ba533b22114691db83a 567 SMART SM01182 229 254 2500.0 T 22-04-2016 IPR018940 Elongation factor 1 beta central acidic region, eukaryote Reactome: REACT_17015|Reactome: REACT_71 HRM2_RS00780 58ef96774dc56acaacbd0125b26fb6fd 78 SUPERFAMILY SSF103263 3 70 8.11E-15 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS00780 58ef96774dc56acaacbd0125b26fb6fd 78 Gene3D G3DSA:3.60.150.10 3 69 2.0E-17 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS00780 58ef96774dc56acaacbd0125b26fb6fd 78 Pfam PF01264 Chorismate synthase 6 64 1.6E-14 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS00780 58ef96774dc56acaacbd0125b26fb6fd 78 PANTHER PTHR21085 1 65 3.8E-20 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS25460 fb9cfe31432c19b041149aa6a10aa3e9 279 Gene3D G3DSA:3.40.50.360 1 177 2.0E-32 T 22-04-2016 IPR029039 Flavoprotein-like domain HRM2_RS25460 fb9cfe31432c19b041149aa6a10aa3e9 279 SUPERFAMILY SSF52218 1 174 5.03E-29 T 22-04-2016 IPR029039 Flavoprotein-like domain HRM2_RS25460 fb9cfe31432c19b041149aa6a10aa3e9 279 PANTHER PTHR10204 1 124 1.3E-26 T 22-04-2016 HRM2_RS25460 fb9cfe31432c19b041149aa6a10aa3e9 279 Pfam PF03358 NADPH-dependent FMN reductase 3 130 3.0E-20 T 22-04-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 HRM2_RS25460 fb9cfe31432c19b041149aa6a10aa3e9 279 PANTHER PTHR10204:SF38 1 124 1.3E-26 T 22-04-2016 HRM2_RS17830 b7ef88d3297b8c11c0751dbdf5faa3c7 180 SUPERFAMILY SSF56053 84 177 2.22E-33 T 22-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 HRM2_RS17830 b7ef88d3297b8c11c0751dbdf5faa3c7 180 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 22-04-2016 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17830 b7ef88d3297b8c11c0751dbdf5faa3c7 180 Pfam PF00347 Ribosomal protein L6 92 165 2.5E-17 T 22-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 HRM2_RS17830 b7ef88d3297b8c11c0751dbdf5faa3c7 180 Pfam PF00347 Ribosomal protein L6 11 83 3.7E-18 T 22-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 HRM2_RS17830 b7ef88d3297b8c11c0751dbdf5faa3c7 180 PRINTS PR00059 Ribosomal protein L6 signature 142 163 3.6E-31 T 22-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 HRM2_RS17830 b7ef88d3297b8c11c0751dbdf5faa3c7 180 PRINTS PR00059 Ribosomal protein L6 signature 72 97 3.6E-31 T 22-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 HRM2_RS17830 b7ef88d3297b8c11c0751dbdf5faa3c7 180 PRINTS PR00059 Ribosomal protein L6 signature 100 116 3.6E-31 T 22-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 HRM2_RS17830 b7ef88d3297b8c11c0751dbdf5faa3c7 180 PANTHER PTHR11655 1 180 8.8E-81 T 22-04-2016 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 HRM2_RS17830 b7ef88d3297b8c11c0751dbdf5faa3c7 180 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 35.215 T 22-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 HRM2_RS17830 b7ef88d3297b8c11c0751dbdf5faa3c7 180 Gene3D G3DSA:3.90.930.12 2 83 3.8E-28 T 22-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 HRM2_RS17830 b7ef88d3297b8c11c0751dbdf5faa3c7 180 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 1.2E-68 T 22-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 HRM2_RS17830 b7ef88d3297b8c11c0751dbdf5faa3c7 180 Gene3D G3DSA:3.90.930.12 84 177 3.4E-36 T 22-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 HRM2_RS17830 b7ef88d3297b8c11c0751dbdf5faa3c7 180 PANTHER PTHR11655:SF14 1 180 8.8E-81 T 22-04-2016 HRM2_RS17830 b7ef88d3297b8c11c0751dbdf5faa3c7 180 PIRSF PIRSF002162 1 178 8.9E-49 T 22-04-2016 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 HRM2_RS17830 b7ef88d3297b8c11c0751dbdf5faa3c7 180 SUPERFAMILY SSF56053 1 83 9.68E-24 T 22-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 HRM2_RS12465 68e399cee57dea1536f701e46c063e8b 393 SUPERFAMILY SSF53822 30 386 5.38E-86 T 22-04-2016 IPR028082 Periplasmic binding protein-like I HRM2_RS12465 68e399cee57dea1536f701e46c063e8b 393 Gene3D G3DSA:3.40.50.2300 30 234 5.0E-53 T 22-04-2016 HRM2_RS12465 68e399cee57dea1536f701e46c063e8b 393 PANTHER PTHR30483 1 385 2.7E-83 T 22-04-2016 HRM2_RS12465 68e399cee57dea1536f701e46c063e8b 393 PANTHER PTHR30483:SF6 1 385 2.7E-83 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HRM2_RS12465 68e399cee57dea1536f701e46c063e8b 393 Pfam PF13458 Periplasmic binding protein 30 381 7.1E-57 T 22-04-2016 IPR028081 Leucine-binding protein domain HRM2_RS14190 430f5a9a662cde330fff6b439d60c494 217 PIRSF PIRSF020269 2 217 2.0E-69 T 22-04-2016 IPR009501 Uncharacterised conserved protein UCP020269 HRM2_RS14190 430f5a9a662cde330fff6b439d60c494 217 PANTHER PTHR36179:SF2 5 217 2.9E-64 T 22-04-2016 HRM2_RS14190 430f5a9a662cde330fff6b439d60c494 217 PANTHER PTHR36179 5 217 2.9E-64 T 22-04-2016 HRM2_RS14190 430f5a9a662cde330fff6b439d60c494 217 Pfam PF02589 Uncharacterised ACR, YkgG family COG1556 14 211 1.2E-47 T 22-04-2016 IPR003741 LUD domain HRM2_RS14190 430f5a9a662cde330fff6b439d60c494 217 Gene3D G3DSA:3.40.50.10420 11 164 4.1E-9 T 22-04-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain HRM2_RS15535 9cf6cded3c4dd7569b0bb82a3e24e3cf 484 SUPERFAMILY SSF56935 24 209 3.08E-5 T 22-04-2016 HRM2_RS15535 9cf6cded3c4dd7569b0bb82a3e24e3cf 484 SUPERFAMILY SSF56935 264 460 2.87E-7 T 22-04-2016 HRM2_RS12835 9f33127d7ec41ffa4f206d23ab2ef044 444 PANTHER PTHR11921 29 442 2.9E-98 T 22-04-2016 HRM2_RS12835 9f33127d7ec41ffa4f206d23ab2ef044 444 PANTHER PTHR11921:SF24 29 442 2.9E-98 T 22-04-2016 HRM2_RS12835 9f33127d7ec41ffa4f206d23ab2ef044 444 Pfam PF02754 Cysteine-rich domain 324 416 4.8E-10 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS12835 9f33127d7ec41ffa4f206d23ab2ef044 444 SUPERFAMILY SSF46548 41 140 2.79E-13 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS12835 9f33127d7ec41ffa4f206d23ab2ef044 444 Pfam PF13534 4Fe-4S dicluster domain 52 125 2.4E-9 T 22-04-2016 HRM2_RS12835 9f33127d7ec41ffa4f206d23ab2ef044 444 Gene3D G3DSA:1.10.1060.10 34 139 8.9E-13 T 22-04-2016 HRM2_RS12835 9f33127d7ec41ffa4f206d23ab2ef044 444 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 110 121 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS07650 4ad32d99d04579b2652d35ccb66c491e 338 Pfam PF13474 SnoaL-like domain 9 130 8.8E-19 T 22-04-2016 IPR009959 Polyketide cyclase SnoaL-like domain HRM2_RS07650 4ad32d99d04579b2652d35ccb66c491e 338 PANTHER PTHR10799:SF750 206 332 1.1E-29 T 22-04-2016 HRM2_RS07650 4ad32d99d04579b2652d35ccb66c491e 338 PANTHER PTHR10799:SF750 1 110 1.1E-29 T 22-04-2016 HRM2_RS07650 4ad32d99d04579b2652d35ccb66c491e 338 Pfam PF00990 Diguanylate cyclase, GGDEF domain 174 332 5.7E-49 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS07650 4ad32d99d04579b2652d35ccb66c491e 338 Gene3D G3DSA:3.30.70.270 174 336 1.9E-49 T 22-04-2016 HRM2_RS07650 4ad32d99d04579b2652d35ccb66c491e 338 SMART SM00267 162 337 3.8E-65 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS07650 4ad32d99d04579b2652d35ccb66c491e 338 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 169 336 4.1E-50 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS07650 4ad32d99d04579b2652d35ccb66c491e 338 PANTHER PTHR10799 206 332 1.1E-29 T 22-04-2016 HRM2_RS07650 4ad32d99d04579b2652d35ccb66c491e 338 PANTHER PTHR10799 1 110 1.1E-29 T 22-04-2016 HRM2_RS07650 4ad32d99d04579b2652d35ccb66c491e 338 SUPERFAMILY SSF54427 5 130 6.03E-11 T 22-04-2016 IPR032710 NTF2-like domain HRM2_RS07650 4ad32d99d04579b2652d35ccb66c491e 338 SUPERFAMILY SSF55073 178 335 2.67E-45 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS02660 da193f52d3d5b69fb80c74c0a14b214e 155 Gene3D G3DSA:3.90.960.10 2 154 3.7E-57 T 22-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 HRM2_RS02660 da193f52d3d5b69fb80c74c0a14b214e 155 PIRSF PIRSF006181 1 155 9.7E-52 T 22-04-2016 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC HRM2_RS02660 da193f52d3d5b69fb80c74c0a14b214e 155 PANTHER PTHR30411 1 155 8.8E-58 T 22-04-2016 HRM2_RS02660 da193f52d3d5b69fb80c74c0a14b214e 155 Pfam PF04073 Aminoacyl-tRNA editing domain 28 145 1.5E-27 T 22-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 HRM2_RS02660 da193f52d3d5b69fb80c74c0a14b214e 155 SUPERFAMILY SSF55826 5 153 1.57E-43 T 22-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 HRM2_RS02660 da193f52d3d5b69fb80c74c0a14b214e 155 PANTHER PTHR30411:SF0 1 155 8.8E-58 T 22-04-2016 HRM2_RS02660 da193f52d3d5b69fb80c74c0a14b214e 155 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 2 154 3.4E-56 T 22-04-2016 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC HRM2_RS11360 fc3e01e883f9df1281e00567fbf0745d 98 PANTHER PTHR33777 1 98 2.0E-46 T 22-04-2016 HRM2_RS11360 fc3e01e883f9df1281e00567fbf0745d 98 SUPERFAMILY SSF89957 1 97 5.23E-36 T 22-04-2016 IPR029756 MTH1187/YkoF-like HRM2_RS11360 fc3e01e883f9df1281e00567fbf0745d 98 Gene3D G3DSA:3.30.70.930 1 97 1.9E-38 T 22-04-2016 IPR029756 MTH1187/YkoF-like HRM2_RS11360 fc3e01e883f9df1281e00567fbf0745d 98 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 3 98 1.3E-36 T 22-04-2016 IPR002767 Thiamine-binding protein HRM2_RS11360 fc3e01e883f9df1281e00567fbf0745d 98 PANTHER PTHR33777:SF1 1 98 2.0E-46 T 22-04-2016 HRM2_RS11360 fc3e01e883f9df1281e00567fbf0745d 98 Pfam PF01910 Thiamine-binding protein 6 95 1.5E-34 T 22-04-2016 IPR002767 Thiamine-binding protein HRM2_RS15090 32b98b093d0fde68b4344c8117b75893 287 SUPERFAMILY SSF74653 185 285 1.44E-17 T 22-04-2016 HRM2_RS15090 32b98b093d0fde68b4344c8117b75893 287 Pfam PF13103 TonB C terminal 198 281 4.8E-16 T 22-04-2016 IPR006260 TonB, C-terminal GO:0006810 HRM2_RS15090 32b98b093d0fde68b4344c8117b75893 287 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 218 281 3.4E-10 T 22-04-2016 IPR006260 TonB, C-terminal GO:0006810 HRM2_RS15090 32b98b093d0fde68b4344c8117b75893 287 Gene3D G3DSA:3.30.1150.10 181 285 1.1E-18 T 22-04-2016 HRM2_RS05330 0ab4c35d553fc6584edf35e9d98e842a 291 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 5 190 7.5E-51 T 22-04-2016 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 HRM2_RS05330 0ab4c35d553fc6584edf35e9d98e842a 291 Pfam PF08029 HisG, C-terminal domain 217 289 3.3E-20 T 22-04-2016 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 HRM2_RS05330 0ab4c35d553fc6584edf35e9d98e842a 291 Pfam PF01634 ATP phosphoribosyltransferase 51 212 6.8E-41 T 22-04-2016 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 HRM2_RS05330 0ab4c35d553fc6584edf35e9d98e842a 291 PANTHER PTHR21403:SF0 1 291 4.7E-77 T 22-04-2016 HRM2_RS05330 0ab4c35d553fc6584edf35e9d98e842a 291 SUPERFAMILY SSF54913 220 290 2.11E-17 T 22-04-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta HRM2_RS05330 0ab4c35d553fc6584edf35e9d98e842a 291 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 193 290 1.1E-25 T 22-04-2016 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 HRM2_RS05330 0ab4c35d553fc6584edf35e9d98e842a 291 Gene3D G3DSA:3.40.190.10 4 148 1.0E-35 T 22-04-2016 HRM2_RS05330 0ab4c35d553fc6584edf35e9d98e842a 291 SUPERFAMILY SSF53850 4 216 3.05E-58 T 22-04-2016 HRM2_RS05330 0ab4c35d553fc6584edf35e9d98e842a 291 PANTHER PTHR21403 1 291 4.7E-77 T 22-04-2016 IPR001348 ATP phosphoribosyltransferase HisG GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 HRM2_RS05330 0ab4c35d553fc6584edf35e9d98e842a 291 Gene3D G3DSA:3.30.70.120 221 290 3.8E-19 T 22-04-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal HRM2_RS05330 0ab4c35d553fc6584edf35e9d98e842a 291 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 4 291 26.135 T 22-04-2016 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 HRM2_RS13215 09ab64d7f017cc0eb1aa486366569964 177 PANTHER PTHR31964 7 175 3.4E-29 T 22-04-2016 HRM2_RS13215 09ab64d7f017cc0eb1aa486366569964 177 SUPERFAMILY SSF52402 8 172 4.74E-32 T 22-04-2016 HRM2_RS13215 09ab64d7f017cc0eb1aa486366569964 177 Pfam PF00582 Universal stress protein family 8 172 1.6E-31 T 22-04-2016 IPR006016 UspA GO:0006950 HRM2_RS13215 09ab64d7f017cc0eb1aa486366569964 177 PANTHER PTHR31964:SF45 7 175 3.4E-29 T 22-04-2016 HRM2_RS13215 09ab64d7f017cc0eb1aa486366569964 177 Gene3D G3DSA:3.40.50.620 7 172 3.4E-37 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS13215 09ab64d7f017cc0eb1aa486366569964 177 PRINTS PR01438 Universal stress protein signature 132 144 2.2E-14 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS13215 09ab64d7f017cc0eb1aa486366569964 177 PRINTS PR01438 Universal stress protein signature 150 172 2.2E-14 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS13215 09ab64d7f017cc0eb1aa486366569964 177 PRINTS PR01438 Universal stress protein signature 8 26 2.2E-14 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS01380 140e77a94c435b4fe5458b94fba2a237 442 PIRSF PIRSF006054 1 435 1.4E-129 T 22-04-2016 IPR021144 Uncharacterised protein family UPF0597 HRM2_RS01380 140e77a94c435b4fe5458b94fba2a237 442 Hamap MF_01845 UPF0597 protein YhaM [yhaM]. 1 433 35.247 T 22-04-2016 IPR021144 Uncharacterised protein family UPF0597 HRM2_RS01380 140e77a94c435b4fe5458b94fba2a237 442 PANTHER PTHR30501 1 436 3.5E-104 T 22-04-2016 HRM2_RS01380 140e77a94c435b4fe5458b94fba2a237 442 Pfam PF03313 Serine dehydratase alpha chain 201 429 2.8E-49 T 22-04-2016 IPR005130 Serine dehydratase-like, alpha subunit HRM2_RS01380 140e77a94c435b4fe5458b94fba2a237 442 PANTHER PTHR30501:SF2 1 436 3.5E-104 T 22-04-2016 HRM2_RS11065 7d9c395228c932965c013c763cb6bad4 402 PRINTS PR00812 Bacterial general secretion pathway protein F signature 366 380 1.7E-14 T 22-04-2016 IPR003004 GspF/PilC family HRM2_RS11065 7d9c395228c932965c013c763cb6bad4 402 PRINTS PR00812 Bacterial general secretion pathway protein F signature 382 401 1.7E-14 T 22-04-2016 IPR003004 GspF/PilC family HRM2_RS11065 7d9c395228c932965c013c763cb6bad4 402 PRINTS PR00812 Bacterial general secretion pathway protein F signature 163 191 1.7E-14 T 22-04-2016 IPR003004 GspF/PilC family HRM2_RS11065 7d9c395228c932965c013c763cb6bad4 402 PRINTS PR00812 Bacterial general secretion pathway protein F signature 64 76 1.7E-14 T 22-04-2016 IPR003004 GspF/PilC family HRM2_RS11065 7d9c395228c932965c013c763cb6bad4 402 PANTHER PTHR30012:SF0 2 402 1.0E-158 T 22-04-2016 HRM2_RS11065 7d9c395228c932965c013c763cb6bad4 402 PANTHER PTHR30012 2 402 1.0E-158 T 22-04-2016 HRM2_RS11065 7d9c395228c932965c013c763cb6bad4 402 Pfam PF00482 Type II secretion system (T2SS), protein F 271 393 4.6E-32 T 22-04-2016 IPR018076 Type II secretion system F domain HRM2_RS11065 7d9c395228c932965c013c763cb6bad4 402 Pfam PF00482 Type II secretion system (T2SS), protein F 68 191 1.3E-32 T 22-04-2016 IPR018076 Type II secretion system F domain HRM2_RS21310 73ff5d7ccffa4e6af7b40eaa36c8a42e 310 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 207 227 1.5E-5 T 22-04-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 HRM2_RS21310 73ff5d7ccffa4e6af7b40eaa36c8a42e 310 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 228 245 1.5E-5 T 22-04-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 HRM2_RS21310 73ff5d7ccffa4e6af7b40eaa36c8a42e 310 SUPERFAMILY SSF50494 127 289 9.17E-17 T 22-04-2016 IPR009003 Peptidase S1, PA clan HRM2_RS21310 73ff5d7ccffa4e6af7b40eaa36c8a42e 310 Gene3D G3DSA:2.40.10.10 209 300 1.2E-13 T 22-04-2016 HRM2_RS13875 0e1a01266ac024b483559ea27e9ab2c3 107 Gene3D G3DSA:1.10.10.710 20 87 1.0E-22 T 22-04-2016 IPR009813 Uncharacterised protein family YebG HRM2_RS13875 0e1a01266ac024b483559ea27e9ab2c3 107 Pfam PF07130 YebG protein 1 74 2.0E-33 T 22-04-2016 IPR009813 Uncharacterised protein family YebG HRM2_RS13730 761981875d03cd0897a2e6ae5a195197 288 SUPERFAMILY SSF48452 102 214 9.86E-5 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS13730 761981875d03cd0897a2e6ae5a195197 288 Gene3D G3DSA:1.25.40.10 99 211 2.7E-4 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS13730 761981875d03cd0897a2e6ae5a195197 288 SUPERFAMILY SSF54523 223 276 2.51E-5 T 22-04-2016 HRM2_RS17710 e43e62bb5afedc3c29f6327b735952d1 523 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 239 516 4.7E-70 T 22-04-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 HRM2_RS17710 e43e62bb5afedc3c29f6327b735952d1 523 SUPERFAMILY SSF53613 239 517 1.38E-74 T 22-04-2016 IPR029056 Ribokinase-like HRM2_RS17710 e43e62bb5afedc3c29f6327b735952d1 523 SUPERFAMILY SSF64153 1 258 6.93E-64 T 22-04-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 HRM2_RS17710 e43e62bb5afedc3c29f6327b735952d1 523 PIRSF PIRSF017184 1 519 1.2E-149 T 22-04-2016 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 HRM2_RS17710 e43e62bb5afedc3c29f6327b735952d1 523 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 236 521 23.054 T 22-04-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 HRM2_RS17710 e43e62bb5afedc3c29f6327b735952d1 523 PANTHER PTHR12592:SF0 1 523 4.5E-146 T 22-04-2016 HRM2_RS17710 e43e62bb5afedc3c29f6327b735952d1 523 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 4 222 4.7E-47 T 22-04-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 HRM2_RS17710 e43e62bb5afedc3c29f6327b735952d1 523 Pfam PF03853 YjeF-related protein N-terminus 26 200 1.2E-44 T 22-04-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 HRM2_RS17710 e43e62bb5afedc3c29f6327b735952d1 523 Gene3D G3DSA:3.40.1190.20 244 517 2.3E-88 T 22-04-2016 IPR029056 Ribokinase-like HRM2_RS17710 e43e62bb5afedc3c29f6327b735952d1 523 Gene3D G3DSA:3.40.50.10260 1 243 3.0E-73 T 22-04-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 HRM2_RS17710 e43e62bb5afedc3c29f6327b735952d1 523 Pfam PF01256 Carbohydrate kinase 259 513 1.7E-60 T 22-04-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 HRM2_RS17710 e43e62bb5afedc3c29f6327b735952d1 523 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 5 221 26.763 T 22-04-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 HRM2_RS17710 e43e62bb5afedc3c29f6327b735952d1 523 PANTHER PTHR12592 1 523 4.5E-146 T 22-04-2016 HRM2_RS17710 e43e62bb5afedc3c29f6327b735952d1 523 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 456 466 - T 22-04-2016 IPR017953 Carbohydrate kinase, predicted, conserved site HRM2_RS02410 0c9e99862393a223e149affa20e2a69f 65 SUPERFAMILY SSF54285 2 65 8.22E-9 T 22-04-2016 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp HRM2_RS02410 0c9e99862393a223e149affa20e2a69f 65 Gene3D G3DSA:3.10.20.30 2 65 3.0E-9 T 22-04-2016 IPR012675 Beta-grasp domain HRM2_RS18815 6fd002b1e00d24fe5b8ad0f51376f32f 136 PANTHER PTHR26402:SF578 1 125 1.9E-35 T 22-04-2016 HRM2_RS18815 6fd002b1e00d24fe5b8ad0f51376f32f 136 Pfam PF00072 Response regulator receiver domain 3 111 1.8E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18815 6fd002b1e00d24fe5b8ad0f51376f32f 136 Gene3D G3DSA:3.40.50.2300 1 127 2.8E-35 T 22-04-2016 HRM2_RS18815 6fd002b1e00d24fe5b8ad0f51376f32f 136 SUPERFAMILY SSF52172 1 124 2.28E-35 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS18815 6fd002b1e00d24fe5b8ad0f51376f32f 136 PANTHER PTHR26402 1 125 1.9E-35 T 22-04-2016 HRM2_RS18815 6fd002b1e00d24fe5b8ad0f51376f32f 136 SMART SM00448 1 112 3.6E-32 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS14015 0adafe37f0609c7da857834c58f9a122 292 SUPERFAMILY SSF103481 39 130 1.7E-11 T 22-04-2016 HRM2_RS14015 0adafe37f0609c7da857834c58f9a122 292 PANTHER PTHR12715 12 279 2.6E-35 T 22-04-2016 HRM2_RS14015 0adafe37f0609c7da857834c58f9a122 292 SUPERFAMILY SSF103481 196 279 1.83E-11 T 22-04-2016 HRM2_RS14015 0adafe37f0609c7da857834c58f9a122 292 Pfam PF00892 EamA-like transporter family 143 278 3.0E-21 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS14015 0adafe37f0609c7da857834c58f9a122 292 Pfam PF00892 EamA-like transporter family 9 130 2.6E-14 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS16015 aebe8eb7496c7556be8b90f0aa7ad4ea 385 SUPERFAMILY SSF52210 239 383 5.49E-50 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS16015 aebe8eb7496c7556be8b90f0aa7ad4ea 385 Pfam PF08442 ATP-grasp domain 2 202 1.8E-77 T 22-04-2016 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS16015 aebe8eb7496c7556be8b90f0aa7ad4ea 385 Hamap MF_00558 Succinyl-CoA ligase [ADP-forming] subunit beta [sucC]. 1 385 41.139 T 22-04-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 HRM2_RS16015 aebe8eb7496c7556be8b90f0aa7ad4ea 385 Pfam PF00549 CoA-ligase 262 381 4.2E-22 T 22-04-2016 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS16015 aebe8eb7496c7556be8b90f0aa7ad4ea 385 Gene3D G3DSA:3.30.470.20 95 239 8.9E-59 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS16015 aebe8eb7496c7556be8b90f0aa7ad4ea 385 Gene3D G3DSA:3.30.1490.20 22 94 4.7E-32 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HRM2_RS16015 aebe8eb7496c7556be8b90f0aa7ad4ea 385 PIRSF PIRSF001554 1 385 5.7E-152 T 22-04-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 HRM2_RS16015 aebe8eb7496c7556be8b90f0aa7ad4ea 385 PANTHER PTHR11815:SF1 1 381 2.4E-217 T 22-04-2016 HRM2_RS16015 aebe8eb7496c7556be8b90f0aa7ad4ea 385 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 281 - T 22-04-2016 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS16015 aebe8eb7496c7556be8b90f0aa7ad4ea 385 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 383 3.8E-158 T 22-04-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 HRM2_RS16015 aebe8eb7496c7556be8b90f0aa7ad4ea 385 Gene3D G3DSA:3.40.50.261 240 382 1.5E-59 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS16015 aebe8eb7496c7556be8b90f0aa7ad4ea 385 SUPERFAMILY SSF56059 1 238 5.83E-83 T 22-04-2016 HRM2_RS16015 aebe8eb7496c7556be8b90f0aa7ad4ea 385 PANTHER PTHR11815 1 381 2.4E-217 T 22-04-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 HRM2_RS06920 1ff477bd44f91c3ec740aa611d571779 380 Gene3D G3DSA:3.90.1150.10 269 377 2.7E-15 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS06920 1ff477bd44f91c3ec740aa611d571779 380 PANTHER PTHR11751 7 380 1.9E-125 T 22-04-2016 HRM2_RS06920 1ff477bd44f91c3ec740aa611d571779 380 PANTHER PTHR11751:SF301 7 380 1.9E-125 T 22-04-2016 HRM2_RS06920 1ff477bd44f91c3ec740aa611d571779 380 Gene3D G3DSA:3.40.640.10 41 268 3.8E-72 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS06920 1ff477bd44f91c3ec740aa611d571779 380 Pfam PF00155 Aminotransferase class I and II 27 375 1.1E-58 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HRM2_RS06920 1ff477bd44f91c3ec740aa611d571779 380 SUPERFAMILY SSF53383 3 379 2.93E-95 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS05855 14ee0625c2c579f472d9fbf8e7696f07 128 SUPERFAMILY SSF52172 4 121 2.85E-35 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS05855 14ee0625c2c579f472d9fbf8e7696f07 128 PANTHER PTHR26402 4 119 2.7E-33 T 22-04-2016 HRM2_RS05855 14ee0625c2c579f472d9fbf8e7696f07 128 Pfam PF00072 Response regulator receiver domain 6 116 5.2E-29 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS05855 14ee0625c2c579f472d9fbf8e7696f07 128 SMART SM00448 4 115 1.7E-32 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS05855 14ee0625c2c579f472d9fbf8e7696f07 128 Gene3D G3DSA:3.40.50.2300 5 123 3.0E-35 T 22-04-2016 HRM2_RS21370 79809e16b372d828e65989a282405385 419 PIRSF PIRSF033091 1 419 2.7E-117 T 22-04-2016 IPR014576 Predicted phosphoesterase, YhaO type HRM2_RS21370 79809e16b372d828e65989a282405385 419 PANTHER PTHR30337 1 292 1.4E-76 T 22-04-2016 HRM2_RS21370 79809e16b372d828e65989a282405385 419 Gene3D G3DSA:3.60.21.10 1 245 5.3E-47 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS21370 79809e16b372d828e65989a282405385 419 Pfam PF00149 Calcineurin-like phosphoesterase 3 197 1.3E-12 T 22-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 HRM2_RS21370 79809e16b372d828e65989a282405385 419 PANTHER PTHR30337:SF7 1 292 1.4E-76 T 22-04-2016 HRM2_RS21370 79809e16b372d828e65989a282405385 419 SUPERFAMILY SSF56300 1 278 4.14E-55 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS15980 b2ae90a550f360ee68c41f05ae798670 297 Gene3D G3DSA:2.130.10.10 51 262 1.0E-6 T 22-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 HRM2_RS15980 b2ae90a550f360ee68c41f05ae798670 297 SUPERFAMILY SSF63825 20 210 3.4E-11 T 22-04-2016 HRM2_RS20510 1442d863bc4901b31c541f8493f8e286 160 PANTHER PTHR36155 1 160 2.2E-95 T 22-04-2016 HRM2_RS20510 1442d863bc4901b31c541f8493f8e286 160 PANTHER PTHR36155:SF1 1 160 2.2E-95 T 22-04-2016 HRM2_RS20510 1442d863bc4901b31c541f8493f8e286 160 Pfam PF04008 Adenosine specific kinase 6 159 4.8E-75 T 22-04-2016 IPR007153 Adenosine specific kinase HRM2_RS20510 1442d863bc4901b31c541f8493f8e286 160 Gene3D G3DSA:3.40.1520.10 1 159 9.1E-78 T 22-04-2016 IPR007153 Adenosine specific kinase HRM2_RS20510 1442d863bc4901b31c541f8493f8e286 160 SUPERFAMILY SSF103165 1 159 9.81E-71 T 22-04-2016 IPR007153 Adenosine specific kinase HRM2_RS18610 d7949fb606ff3c789b9533d54f7f1bc1 386 Pfam PF10263 SprT-like family 55 129 7.2E-7 T 22-04-2016 IPR006640 SprT-like HRM2_RS18610 d7949fb606ff3c789b9533d54f7f1bc1 386 Pfam PF10979 Protein of unknown function (DUF2786) 154 191 4.4E-13 T 22-04-2016 IPR024498 Domain of unknown function DUF2786 HRM2_RS11100 930234b42b040a0e0df9dc60248506d1 231 PANTHER PTHR24220:SF111 11 224 1.8E-93 T 22-04-2016 HRM2_RS11100 930234b42b040a0e0df9dc60248506d1 231 SUPERFAMILY SSF52540 10 227 2.54E-63 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11100 930234b42b040a0e0df9dc60248506d1 231 SMART SM00382 38 226 2.2E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS11100 930234b42b040a0e0df9dc60248506d1 231 Gene3D G3DSA:3.40.50.300 9 229 5.7E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11100 930234b42b040a0e0df9dc60248506d1 231 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS11100 930234b42b040a0e0df9dc60248506d1 231 Pfam PF00005 ABC transporter 29 177 2.3E-29 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS11100 930234b42b040a0e0df9dc60248506d1 231 PANTHER PTHR24220 11 224 1.8E-93 T 22-04-2016 HRM2_RS22460 c96ff2a649ee46d9b8e6405fa130b3a2 321 PANTHER PTHR18895:SF61 23 319 2.9E-77 T 22-04-2016 HRM2_RS22460 c96ff2a649ee46d9b8e6405fa130b3a2 321 SUPERFAMILY SSF53335 18 282 1.48E-52 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS22460 c96ff2a649ee46d9b8e6405fa130b3a2 321 PANTHER PTHR18895 23 319 2.9E-77 T 22-04-2016 HRM2_RS22460 c96ff2a649ee46d9b8e6405fa130b3a2 321 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 104 284 6.5E-20 T 22-04-2016 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 HRM2_RS22460 c96ff2a649ee46d9b8e6405fa130b3a2 321 Gene3D G3DSA:3.40.50.150 54 320 6.2E-62 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS15995 1f53602350bf13bf6aa181accce24b63 244 PANTHER PTHR11921:SF13 1 244 9.3E-90 T 22-04-2016 HRM2_RS15995 1f53602350bf13bf6aa181accce24b63 244 SUPERFAMILY SSF54292 6 108 1.62E-25 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 HRM2_RS15995 1f53602350bf13bf6aa181accce24b63 244 SUPERFAMILY SSF46548 114 242 4.19E-22 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS15995 1f53602350bf13bf6aa181accce24b63 244 Gene3D G3DSA:1.10.1060.10 114 242 5.9E-28 T 22-04-2016 HRM2_RS15995 1f53602350bf13bf6aa181accce24b63 244 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 9 114 3.3E-28 T 22-04-2016 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 HRM2_RS15995 1f53602350bf13bf6aa181accce24b63 244 Gene3D G3DSA:3.10.20.30 3 108 1.2E-32 T 22-04-2016 IPR012675 Beta-grasp domain HRM2_RS15995 1f53602350bf13bf6aa181accce24b63 244 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 60 68 - T 22-04-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 HRM2_RS15995 1f53602350bf13bf6aa181accce24b63 244 Pfam PF13183 4Fe-4S dicluster domain 152 226 1.3E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS15995 1f53602350bf13bf6aa181accce24b63 244 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 12 236 2.6E-50 T 22-04-2016 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 HRM2_RS15995 1f53602350bf13bf6aa181accce24b63 244 PANTHER PTHR11921 1 244 9.3E-90 T 22-04-2016 HRM2_RS08270 08960eee39f135edf5274b8c0de6447d 446 Pfam PF04060 Putative Fe-S cluster 12 44 3.9E-13 T 22-04-2016 IPR007202 4Fe-4S domain GO:0051536 HRM2_RS08270 08960eee39f135edf5274b8c0de6447d 446 PANTHER PTHR36214 1 446 2.2E-120 T 22-04-2016 HRM2_RS08270 08960eee39f135edf5274b8c0de6447d 446 PIRSF PIRSF000376 1 446 2.7E-137 T 22-04-2016 IPR016218 Acetyl-CoA decarbonylase/synthase complex, gamma subunit GO:0005506|GO:0008168|GO:0046356 HRM2_RS08270 08960eee39f135edf5274b8c0de6447d 446 SUPERFAMILY SSF51717 138 290 3.92E-7 T 22-04-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 HRM2_RS08270 08960eee39f135edf5274b8c0de6447d 446 Pfam PF03599 CO dehydrogenase/acetyl-CoA synthase delta subunit 64 442 3.3E-83 T 22-04-2016 IPR016041 CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel HRM2_RS08270 08960eee39f135edf5274b8c0de6447d 446 PANTHER PTHR36214:SF4 1 446 2.2E-120 T 22-04-2016 HRM2_RS04795 14ff6cf2a1666444649603380a16102a 424 SUPERFAMILY SSF53146 297 398 3.53E-23 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS04795 14ff6cf2a1666444649603380a16102a 424 Gene3D G3DSA:3.20.20.70 18 269 1.5E-42 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS04795 14ff6cf2a1666444649603380a16102a 424 PANTHER PTHR11228 4 379 1.5E-84 T 22-04-2016 HRM2_RS04795 14ff6cf2a1666444649603380a16102a 424 PANTHER PTHR11228:SF18 4 379 1.5E-84 T 22-04-2016 HRM2_RS04795 14ff6cf2a1666444649603380a16102a 424 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 24 35 - T 22-04-2016 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 HRM2_RS04795 14ff6cf2a1666444649603380a16102a 424 SUPERFAMILY SSF102114 19 257 3.66E-39 T 22-04-2016 HRM2_RS04795 14ff6cf2a1666444649603380a16102a 424 Pfam PF04055 Radical SAM superfamily 23 204 3.2E-20 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS04795 14ff6cf2a1666444649603380a16102a 424 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 307 396 4.5E-14 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS04795 14ff6cf2a1666444649603380a16102a 424 Pfam PF13394 4Fe-4S single cluster domain 27 115 1.1E-4 T 22-04-2016 HRM2_RS04795 14ff6cf2a1666444649603380a16102a 424 Gene3D G3DSA:3.30.420.130 293 398 7.5E-27 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS04795 14ff6cf2a1666444649603380a16102a 424 SMART SM00729 18 247 1.4E-4 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS10530 5a0e1832cb3b951a29a003710d204bb1 422 Pfam PF13458 Periplasmic binding protein 33 397 9.0E-55 T 22-04-2016 IPR028081 Leucine-binding protein domain HRM2_RS10530 5a0e1832cb3b951a29a003710d204bb1 422 SUPERFAMILY SSF53822 33 420 8.41E-73 T 22-04-2016 IPR028082 Periplasmic binding protein-like I HRM2_RS10530 5a0e1832cb3b951a29a003710d204bb1 422 Gene3D G3DSA:3.40.50.2300 33 246 1.3E-51 T 22-04-2016 HRM2_RS10530 5a0e1832cb3b951a29a003710d204bb1 422 PANTHER PTHR30483 3 416 5.2E-59 T 22-04-2016 HRM2_RS13945 7afbe1b6c6f47564fe3227837ac52209 314 Pfam PF13145 PPIC-type PPIASE domain 160 282 3.5E-16 T 22-04-2016 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 HRM2_RS13945 7afbe1b6c6f47564fe3227837ac52209 314 PANTHER PTHR10657:SF11 1 313 7.0E-48 T 22-04-2016 HRM2_RS13945 7afbe1b6c6f47564fe3227837ac52209 314 Pfam PF09312 SurA N-terminal domain 29 145 4.2E-20 T 22-04-2016 IPR015391 SurA N-terminal HRM2_RS13945 7afbe1b6c6f47564fe3227837ac52209 314 Gene3D G3DSA:3.10.50.40 172 290 1.4E-22 T 22-04-2016 HRM2_RS13945 7afbe1b6c6f47564fe3227837ac52209 314 SUPERFAMILY SSF109998 29 209 1.92E-34 T 22-04-2016 IPR027304 Trigger factor/SurA domain HRM2_RS13945 7afbe1b6c6f47564fe3227837ac52209 314 PANTHER PTHR10657 1 313 7.0E-48 T 22-04-2016 HRM2_RS13945 7afbe1b6c6f47564fe3227837ac52209 314 SUPERFAMILY SSF54534 181 271 9.42E-18 T 22-04-2016 HRM2_RS20750 3e3ce4681fb2975e1c75b59e626deb29 355 Gene3D G3DSA:3.30.450.40 174 344 4.5E-23 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS20750 3e3ce4681fb2975e1c75b59e626deb29 355 Gene3D G3DSA:3.30.450.40 17 171 4.9E-31 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS20750 3e3ce4681fb2975e1c75b59e626deb29 355 SUPERFAMILY SSF55781 174 334 3.27E-16 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS20750 3e3ce4681fb2975e1c75b59e626deb29 355 SMART SM00065 195 338 0.0022 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS20750 3e3ce4681fb2975e1c75b59e626deb29 355 SMART SM00065 31 177 7.7E-20 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS20750 3e3ce4681fb2975e1c75b59e626deb29 355 Pfam PF01590 GAF domain 32 167 8.5E-16 T 22-04-2016 IPR003018 GAF domain GO:0005515 HRM2_RS20750 3e3ce4681fb2975e1c75b59e626deb29 355 SUPERFAMILY SSF55781 16 173 2.62E-25 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS19150 646415000e6edc8cb013345785bc4b25 186 Gene3D G3DSA:3.40.50.2020 37 169 4.9E-28 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like HRM2_RS19150 646415000e6edc8cb013345785bc4b25 186 PANTHER PTHR11776 3 179 4.0E-40 T 22-04-2016 HRM2_RS19150 646415000e6edc8cb013345785bc4b25 186 PANTHER PTHR11776:SF10 3 179 4.0E-40 T 22-04-2016 HRM2_RS19150 646415000e6edc8cb013345785bc4b25 186 Pfam PF00156 Phosphoribosyl transferase domain 45 170 8.1E-17 T 22-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 HRM2_RS19150 646415000e6edc8cb013345785bc4b25 186 SUPERFAMILY SSF53271 14 168 2.56E-24 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like HRM2_RS01150 2d4bc34123108a1cc659c67c1b09c056 1047 SUPERFAMILY SSF82714 188 272 1.28E-11 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS01150 2d4bc34123108a1cc659c67c1b09c056 1047 Gene3D G3DSA:1.10.3850.10 805 1022 3.9E-57 T 22-04-2016 HRM2_RS01150 2d4bc34123108a1cc659c67c1b09c056 1047 Gene3D G3DSA:1.10.3850.10 280 492 9.1E-42 T 22-04-2016 HRM2_RS01150 2d4bc34123108a1cc659c67c1b09c056 1047 Pfam PF00873 AcrB/AcrD/AcrF family 22 1021 5.2E-159 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS01150 2d4bc34123108a1cc659c67c1b09c056 1047 PANTHER PTHR32063:SF33 11 1029 0.0 T 22-04-2016 HRM2_RS01150 2d4bc34123108a1cc659c67c1b09c056 1047 SUPERFAMILY SSF82693 53 140 6.28E-20 T 22-04-2016 HRM2_RS01150 2d4bc34123108a1cc659c67c1b09c056 1047 SUPERFAMILY SSF82866 799 1023 2.09E-46 T 22-04-2016 HRM2_RS01150 2d4bc34123108a1cc659c67c1b09c056 1047 Gene3D G3DSA:3.30.2090.10 187 274 2.8E-10 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS01150 2d4bc34123108a1cc659c67c1b09c056 1047 PRINTS PR00702 Acriflavin resistance protein family signature 362 383 4.9E-26 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS01150 2d4bc34123108a1cc659c67c1b09c056 1047 PRINTS PR00702 Acriflavin resistance protein family signature 443 466 4.9E-26 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS01150 2d4bc34123108a1cc659c67c1b09c056 1047 PRINTS PR00702 Acriflavin resistance protein family signature 48 66 4.9E-26 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS01150 2d4bc34123108a1cc659c67c1b09c056 1047 PRINTS PR00702 Acriflavin resistance protein family signature 20 44 4.9E-26 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS01150 2d4bc34123108a1cc659c67c1b09c056 1047 PRINTS PR00702 Acriflavin resistance protein family signature 390 414 4.9E-26 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS01150 2d4bc34123108a1cc659c67c1b09c056 1047 SUPERFAMILY SSF82693 155 187 5.75E-7 T 22-04-2016 HRM2_RS01150 2d4bc34123108a1cc659c67c1b09c056 1047 SUPERFAMILY SSF82693 274 330 5.75E-7 T 22-04-2016 HRM2_RS01150 2d4bc34123108a1cc659c67c1b09c056 1047 PANTHER PTHR32063 11 1029 0.0 T 22-04-2016 HRM2_RS01150 2d4bc34123108a1cc659c67c1b09c056 1047 Gene3D G3DSA:3.30.70.1430 54 147 3.4E-23 T 22-04-2016 HRM2_RS01150 2d4bc34123108a1cc659c67c1b09c056 1047 Gene3D G3DSA:3.30.2090.10 728 799 2.3E-4 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS01150 2d4bc34123108a1cc659c67c1b09c056 1047 SUPERFAMILY SSF82866 304 492 9.02E-37 T 22-04-2016 HRM2_RS14055 5805f70d7664fa50da699897a2975b64 245 SUPERFAMILY SSF46548 29 104 2.09E-15 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS14055 5805f70d7664fa50da699897a2975b64 245 PANTHER PTHR11921:SF24 30 240 2.8E-14 T 22-04-2016 HRM2_RS14055 5805f70d7664fa50da699897a2975b64 245 Gene3D G3DSA:1.10.1060.10 29 104 3.0E-14 T 22-04-2016 HRM2_RS14055 5805f70d7664fa50da699897a2975b64 245 Pfam PF13183 4Fe-4S dicluster domain 30 91 6.1E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS14055 5805f70d7664fa50da699897a2975b64 245 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 33 44 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS14055 5805f70d7664fa50da699897a2975b64 245 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 77 88 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS14055 5805f70d7664fa50da699897a2975b64 245 PANTHER PTHR11921 30 240 2.8E-14 T 22-04-2016 HRM2_RS09940 3387e12567bbd2e052c65275d5c89ba1 64 SUPERFAMILY SSF143100 4 62 3.14E-17 T 22-04-2016 HRM2_RS10015 526a0ba75ec917e38df902683e221bc8 251 Gene3D G3DSA:2.50.20.10 26 249 5.6E-63 T 22-04-2016 HRM2_RS10015 526a0ba75ec917e38df902683e221bc8 251 Pfam PF17131 Outer membrane lipoprotein-sorting protein 73 248 2.3E-44 T 22-04-2016 IPR033399 Putative outer membrane lipoprotein-sorting protein HRM2_RS10015 526a0ba75ec917e38df902683e221bc8 251 PIRSF PIRSF028205 2 251 1.8E-66 T 22-04-2016 IPR011220 Uncharacterised conserved protein UCP028205 HRM2_RS10015 526a0ba75ec917e38df902683e221bc8 251 SUPERFAMILY SSF89392 31 198 4.71E-5 T 22-04-2016 IPR029046 Lipoprotein localisation LolA/LolB/LppX HRM2_RS17200 d825c8fbc8cd8e57af0554970e6e88b4 380 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 194 213 - T 22-04-2016 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site HRM2_RS17200 d825c8fbc8cd8e57af0554970e6e88b4 380 Gene3D G3DSA:3.40.640.10 16 247 2.4E-89 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS17200 d825c8fbc8cd8e57af0554970e6e88b4 380 PANTHER PTHR11601 4 379 3.1E-170 T 22-04-2016 HRM2_RS17200 d825c8fbc8cd8e57af0554970e6e88b4 380 Gene3D G3DSA:3.90.1150.10 248 372 7.4E-41 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS17200 d825c8fbc8cd8e57af0554970e6e88b4 380 PANTHER PTHR11601:SF20 4 379 3.1E-170 T 22-04-2016 HRM2_RS17200 d825c8fbc8cd8e57af0554970e6e88b4 380 Pfam PF00266 Aminotransferase class-V 5 365 6.1E-75 T 22-04-2016 IPR000192 Aminotransferase class V domain HRM2_RS17200 d825c8fbc8cd8e57af0554970e6e88b4 380 SUPERFAMILY SSF53383 4 376 1.18E-105 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS17200 d825c8fbc8cd8e57af0554970e6e88b4 380 PIRSF PIRSF005572 3 380 5.2E-126 T 22-04-2016 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 HRM2_RS09000 1468ccb7ea50d0650137d2a259a2e9a8 221 SUPERFAMILY SSF69796 10 208 8.76E-49 T 22-04-2016 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 HRM2_RS09000 1468ccb7ea50d0650137d2a259a2e9a8 221 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 22 204 4.5E-37 T 22-04-2016 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 HRM2_RS09000 1468ccb7ea50d0650137d2a259a2e9a8 221 Pfam PF02511 Thymidylate synthase complementing protein 21 199 3.1E-43 T 22-04-2016 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 HRM2_RS09000 1468ccb7ea50d0650137d2a259a2e9a8 221 PANTHER PTHR34934 1 207 6.9E-29 T 22-04-2016 HRM2_RS25340 def930ca5a2d593c1027d1ca4149dd41 845 PANTHER PTHR30347 573 845 8.5E-74 T 22-04-2016 HRM2_RS25340 def930ca5a2d593c1027d1ca4149dd41 845 Gene3D G3DSA:3.30.70.100 746 830 1.4E-21 T 22-04-2016 HRM2_RS25340 def930ca5a2d593c1027d1ca4149dd41 845 SUPERFAMILY SSF82861 591 675 1.44E-10 T 22-04-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 HRM2_RS25340 def930ca5a2d593c1027d1ca4149dd41 845 SUPERFAMILY SSF50182 676 742 4.9E-17 T 22-04-2016 IPR010920 LSM domain HRM2_RS25340 def930ca5a2d593c1027d1ca4149dd41 845 Pfam PF00924 Mechanosensitive ion channel 635 832 1.2E-52 T 22-04-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 HRM2_RS25340 def930ca5a2d593c1027d1ca4149dd41 845 SUPERFAMILY SSF82689 744 842 2.22E-26 T 22-04-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 HRM2_RS25340 def930ca5a2d593c1027d1ca4149dd41 845 PANTHER PTHR30347:SF3 573 845 8.5E-74 T 22-04-2016 HRM2_RS25340 def930ca5a2d593c1027d1ca4149dd41 845 Gene3D G3DSA:2.30.30.60 692 741 1.7E-15 T 22-04-2016 HRM2_RS08135 5492358a2422e825b289f6432ce95bcb 269 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 23 71 1.9E-20 T 22-04-2016 IPR025713 Motility protein B, N-terminal domain HRM2_RS08135 5492358a2422e825b289f6432ce95bcb 269 SUPERFAMILY SSF103088 139 254 5.1E-30 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS08135 5492358a2422e825b289f6432ce95bcb 269 PANTHER PTHR30329 27 256 2.2E-62 T 22-04-2016 HRM2_RS08135 5492358a2422e825b289f6432ce95bcb 269 Pfam PF00691 OmpA family 150 248 1.7E-19 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS08135 5492358a2422e825b289f6432ce95bcb 269 Gene3D G3DSA:3.30.1330.60 132 253 2.2E-32 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS08135 5492358a2422e825b289f6432ce95bcb 269 PANTHER PTHR30329:SF4 27 256 2.2E-62 T 22-04-2016 HRM2_RS12150 76d38a80330820432abc061935ad0203 241 SUPERFAMILY SSF52540 25 215 2.0E-19 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12150 76d38a80330820432abc061935ad0203 241 Gene3D G3DSA:3.40.50.300 12 213 6.2E-20 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12150 76d38a80330820432abc061935ad0203 241 PANTHER PTHR24220 63 211 1.6E-17 T 22-04-2016 HRM2_RS12150 76d38a80330820432abc061935ad0203 241 PANTHER PTHR24220:SF301 63 211 1.6E-17 T 22-04-2016 HRM2_RS23930 5891e67714be4c12fe769c539527b82d 1037 Gene3D G3DSA:3.30.70.1430 41 139 3.9E-24 T 22-04-2016 HRM2_RS23930 5891e67714be4c12fe769c539527b82d 1037 SUPERFAMILY SSF82866 291 493 9.81E-43 T 22-04-2016 HRM2_RS23930 5891e67714be4c12fe769c539527b82d 1037 PRINTS PR00702 Acriflavin resistance protein family signature 466 489 6.5E-47 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS23930 5891e67714be4c12fe769c539527b82d 1037 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 6.5E-47 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS23930 5891e67714be4c12fe769c539527b82d 1037 PRINTS PR00702 Acriflavin resistance protein family signature 441 464 6.5E-47 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS23930 5891e67714be4c12fe769c539527b82d 1037 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 6.5E-47 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS23930 5891e67714be4c12fe769c539527b82d 1037 PRINTS PR00702 Acriflavin resistance protein family signature 388 412 6.5E-47 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS23930 5891e67714be4c12fe769c539527b82d 1037 PRINTS PR00702 Acriflavin resistance protein family signature 333 356 6.5E-47 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS23930 5891e67714be4c12fe769c539527b82d 1037 PRINTS PR00702 Acriflavin resistance protein family signature 360 381 6.5E-47 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS23930 5891e67714be4c12fe769c539527b82d 1037 Gene3D G3DSA:3.30.70.1320 271 298 5.6E-8 T 22-04-2016 HRM2_RS23930 5891e67714be4c12fe769c539527b82d 1037 Gene3D G3DSA:3.30.70.1320 149 180 5.6E-8 T 22-04-2016 HRM2_RS23930 5891e67714be4c12fe769c539527b82d 1037 Gene3D G3DSA:1.20.1640.10 299 498 8.5E-56 T 22-04-2016 HRM2_RS23930 5891e67714be4c12fe769c539527b82d 1037 Gene3D G3DSA:3.30.2090.10 713 798 1.4E-8 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS23930 5891e67714be4c12fe769c539527b82d 1037 Gene3D G3DSA:3.30.2090.10 185 266 1.6E-11 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS23930 5891e67714be4c12fe769c539527b82d 1037 SUPERFAMILY SSF82866 796 1029 4.19E-40 T 22-04-2016 HRM2_RS23930 5891e67714be4c12fe769c539527b82d 1037 SUPERFAMILY SSF82693 138 183 3.4E-11 T 22-04-2016 HRM2_RS23930 5891e67714be4c12fe769c539527b82d 1037 SUPERFAMILY SSF82693 269 311 3.4E-11 T 22-04-2016 HRM2_RS23930 5891e67714be4c12fe769c539527b82d 1037 PANTHER PTHR32063:SF0 1 1023 1.0E-233 T 22-04-2016 HRM2_RS23930 5891e67714be4c12fe769c539527b82d 1037 Gene3D G3DSA:1.10.3850.10 804 1027 3.0E-50 T 22-04-2016 HRM2_RS23930 5891e67714be4c12fe769c539527b82d 1037 SUPERFAMILY SSF82693 41 129 7.32E-20 T 22-04-2016 HRM2_RS23930 5891e67714be4c12fe769c539527b82d 1037 SUPERFAMILY SSF82714 713 799 4.05E-9 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS23930 5891e67714be4c12fe769c539527b82d 1037 PANTHER PTHR32063 1 1023 1.0E-233 T 22-04-2016 HRM2_RS23930 5891e67714be4c12fe769c539527b82d 1037 Pfam PF00873 AcrB/AcrD/AcrF family 3 1026 3.4E-195 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS23930 5891e67714be4c12fe769c539527b82d 1037 SUPERFAMILY SSF82714 185 267 8.24E-11 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS05300 49efc3d41b1f65856e661cf0f0e90a39 353 PANTHER PTHR11825:SF44 2 352 2.0E-146 T 22-04-2016 HRM2_RS05300 49efc3d41b1f65856e661cf0f0e90a39 353 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 41 353 5.7E-120 T 22-04-2016 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: REACT_13 HRM2_RS05300 49efc3d41b1f65856e661cf0f0e90a39 353 SUPERFAMILY SSF56752 15 350 1.31E-113 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 HRM2_RS05300 49efc3d41b1f65856e661cf0f0e90a39 353 PANTHER PTHR11825 2 352 2.0E-146 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 HRM2_RS05300 49efc3d41b1f65856e661cf0f0e90a39 353 Gene3D G3DSA:3.20.10.10 172 340 5.7E-66 T 22-04-2016 HRM2_RS05300 49efc3d41b1f65856e661cf0f0e90a39 353 PIRSF PIRSF006468 1 353 2.4E-130 T 22-04-2016 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: REACT_13 HRM2_RS05300 49efc3d41b1f65856e661cf0f0e90a39 353 Pfam PF01063 Amino-transferase class IV 66 309 7.5E-37 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 HRM2_RS05300 49efc3d41b1f65856e661cf0f0e90a39 353 Gene3D G3DSA:3.30.470.10 3 171 5.5E-67 T 22-04-2016 HRM2_RS05300 49efc3d41b1f65856e661cf0f0e90a39 353 ProSitePatterns PS00770 Aminotransferases class-IV signature. 230 259 - T 22-04-2016 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: REACT_13 HRM2_RS18255 1d0edf87235a9cfa72227ed145c2f7c2 234 Hamap MF_00415 Flagellar L-ring protein [flgH]. 2 232 23.883 T 22-04-2016 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 HRM2_RS18255 1d0edf87235a9cfa72227ed145c2f7c2 234 PANTHER PTHR34933 44 234 2.8E-52 T 22-04-2016 HRM2_RS18255 1d0edf87235a9cfa72227ed145c2f7c2 234 PANTHER PTHR34933:SF1 44 234 2.8E-52 T 22-04-2016 HRM2_RS18255 1d0edf87235a9cfa72227ed145c2f7c2 234 Pfam PF02107 Flagellar L-ring protein 52 233 4.8E-55 T 22-04-2016 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 HRM2_RS18255 1d0edf87235a9cfa72227ed145c2f7c2 234 PRINTS PR01008 Flagellar L-ring protein signature 211 225 6.4E-22 T 22-04-2016 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 HRM2_RS18255 1d0edf87235a9cfa72227ed145c2f7c2 234 PRINTS PR01008 Flagellar L-ring protein signature 195 209 6.4E-22 T 22-04-2016 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 HRM2_RS18255 1d0edf87235a9cfa72227ed145c2f7c2 234 PRINTS PR01008 Flagellar L-ring protein signature 148 163 6.4E-22 T 22-04-2016 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 HRM2_RS18255 1d0edf87235a9cfa72227ed145c2f7c2 234 PRINTS PR01008 Flagellar L-ring protein signature 74 86 6.4E-22 T 22-04-2016 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 HRM2_RS18255 1d0edf87235a9cfa72227ed145c2f7c2 234 PRINTS PR01008 Flagellar L-ring protein signature 174 190 6.4E-22 T 22-04-2016 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 HRM2_RS17845 7d16502a4e06e98827559bcb0bca6c20 109 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 5 107 4.6E-35 T 22-04-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17845 7d16502a4e06e98827559bcb0bca6c20 109 SUPERFAMILY SSF50104 5 105 7.02E-35 T 22-04-2016 IPR008991 Translation protein SH3-like domain HRM2_RS17845 7d16502a4e06e98827559bcb0bca6c20 109 Gene3D G3DSA:2.30.30.30 5 96 1.8E-24 T 22-04-2016 IPR014722 Ribosomal protein L2 domain 2 HRM2_RS17845 7d16502a4e06e98827559bcb0bca6c20 109 SMART SM00739 7 34 3.5E-4 T 22-04-2016 IPR005824 KOW HRM2_RS17845 7d16502a4e06e98827559bcb0bca6c20 109 PANTHER PTHR12903 5 108 4.2E-39 T 22-04-2016 HRM2_RS17845 7d16502a4e06e98827559bcb0bca6c20 109 Pfam PF00467 KOW motif 12 41 5.7E-8 T 22-04-2016 IPR005824 KOW HRM2_RS17845 7d16502a4e06e98827559bcb0bca6c20 109 ProSitePatterns PS01108 Ribosomal protein L24 signature. 11 28 - T 22-04-2016 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17845 7d16502a4e06e98827559bcb0bca6c20 109 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 6 101 19.262 T 22-04-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17845 7d16502a4e06e98827559bcb0bca6c20 109 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 43 107 3.9E-25 T 22-04-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS12635 d2a00f05c598ffebfad53894adbb6d72 483 SUPERFAMILY SSF53098 81 416 7.59E-31 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS12635 d2a00f05c598ffebfad53894adbb6d72 483 Pfam PF13546 DDE superfamily endonuclease 61 271 1.9E-23 T 22-04-2016 HRM2_RS23050 78b9bd5e261ea3d1c40788594a9eec53 158 PANTHER PTHR35011 1 144 1.0E-14 T 22-04-2016 HRM2_RS23050 78b9bd5e261ea3d1c40788594a9eec53 158 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 26 157 1.0E-19 T 22-04-2016 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component HRM2_RS03325 2b5b227b1c10874d39d21346234f9ce1 285 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 37 184 1.1E-14 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HRM2_RS03325 2b5b227b1c10874d39d21346234f9ce1 285 SMART SM00382 33 193 1.8E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS03325 2b5b227b1c10874d39d21346234f9ce1 285 PANTHER PTHR22908 11 245 4.5E-47 T 22-04-2016 HRM2_RS03325 2b5b227b1c10874d39d21346234f9ce1 285 Gene3D G3DSA:3.40.50.300 30 212 3.4E-30 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03325 2b5b227b1c10874d39d21346234f9ce1 285 SUPERFAMILY SSF52540 33 250 6.74E-36 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07915 fe854f69b96801539a95fc9ad61347e8 387 SUPERFAMILY SSF103473 11 373 1.01E-27 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS07915 fe854f69b96801539a95fc9ad61347e8 387 Gene3D G3DSA:1.20.1250.20 14 190 1.0E-13 T 22-04-2016 HRM2_RS07915 fe854f69b96801539a95fc9ad61347e8 387 Pfam PF07690 Major Facilitator Superfamily 14 325 1.3E-11 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS07915 fe854f69b96801539a95fc9ad61347e8 387 Gene3D G3DSA:1.20.1250.20 199 372 4.6E-12 T 22-04-2016 HRM2_RS01040 4ba6c9338e1b8b2a39e3d90f306e83f6 115 SUPERFAMILY SSF54593 9 115 1.28E-16 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HRM2_RS01040 4ba6c9338e1b8b2a39e3d90f306e83f6 115 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 113 5.7E-6 T 22-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain HRM2_RS01040 4ba6c9338e1b8b2a39e3d90f306e83f6 115 Gene3D G3DSA:3.10.180.10 1 114 2.9E-16 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HRM2_RS23420 a9718bbedca94273d612274d67807839 186 Pfam PF01980 Uncharacterised protein family UPF0066 57 164 3.9E-26 T 22-04-2016 IPR023370 TsaA-like domain HRM2_RS23420 a9718bbedca94273d612274d67807839 186 PANTHER PTHR12818 63 178 2.1E-31 T 22-04-2016 HRM2_RS23420 a9718bbedca94273d612274d67807839 186 SUPERFAMILY SSF118196 17 181 4.58E-38 T 22-04-2016 IPR023370 TsaA-like domain HRM2_RS23420 a9718bbedca94273d612274d67807839 186 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 49 164 3.7E-29 T 22-04-2016 IPR023370 TsaA-like domain HRM2_RS23420 a9718bbedca94273d612274d67807839 186 Gene3D G3DSA:2.40.30.70 18 182 1.6E-38 T 22-04-2016 IPR023370 TsaA-like domain HRM2_RS13545 5e11819ac1702c327605830d88d12be6 149 PIRSF PIRSF006162 1 149 8.5E-42 T 22-04-2016 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|UniPathway: UPA00084 HRM2_RS13545 5e11819ac1702c327605830d88d12be6 149 PANTHER PTHR36305 1 149 1.7E-42 T 22-04-2016 HRM2_RS13545 5e11819ac1702c327605830d88d12be6 149 Gene3D G3DSA:1.10.3760.10 69 147 3.1E-4 T 22-04-2016 IPR027416 YutG-like domain HRM2_RS13545 5e11819ac1702c327605830d88d12be6 149 Pfam PF04608 Phosphatidylglycerophosphatase A 11 148 5.1E-41 T 22-04-2016 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 HRM2_RS13545 5e11819ac1702c327605830d88d12be6 149 SUPERFAMILY SSF101307 4 148 3.53E-31 T 22-04-2016 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 HRM2_RS21840 cf5c0d9c2230dfab5889f9f5caee524f 179 Pfam PF00665 Integrase core domain 53 164 4.3E-7 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 HRM2_RS21840 cf5c0d9c2230dfab5889f9f5caee524f 179 Gene3D G3DSA:3.30.420.10 48 167 4.8E-7 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS21840 cf5c0d9c2230dfab5889f9f5caee524f 179 SUPERFAMILY SSF53098 52 173 8.16E-13 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS13305 e9a4696686ac9d37c14cf3d0c9bb246e 339 PANTHER PTHR10366 2 339 9.4E-152 T 22-04-2016 HRM2_RS13305 e9a4696686ac9d37c14cf3d0c9bb246e 339 Gene3D G3DSA:3.40.50.720 1 181 3.1E-52 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS13305 e9a4696686ac9d37c14cf3d0c9bb246e 339 SUPERFAMILY SSF51735 1 338 3.06E-96 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS13305 e9a4696686ac9d37c14cf3d0c9bb246e 339 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 337 4.7E-137 T 22-04-2016 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|UniPathway: UPA00214 HRM2_RS13305 e9a4696686ac9d37c14cf3d0c9bb246e 339 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 326 2.6E-58 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS13305 e9a4696686ac9d37c14cf3d0c9bb246e 339 PANTHER PTHR10366:SF39 2 339 9.4E-152 T 22-04-2016 HRM2_RS13305 e9a4696686ac9d37c14cf3d0c9bb246e 339 PRINTS PR01713 Nucleotide sugar epimerase signature 258 273 1.2E-5 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 HRM2_RS13305 e9a4696686ac9d37c14cf3d0c9bb246e 339 PRINTS PR01713 Nucleotide sugar epimerase signature 233 248 1.2E-5 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 HRM2_RS13305 e9a4696686ac9d37c14cf3d0c9bb246e 339 PRINTS PR01713 Nucleotide sugar epimerase signature 297 314 1.2E-5 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 HRM2_RS13305 e9a4696686ac9d37c14cf3d0c9bb246e 339 PRINTS PR01713 Nucleotide sugar epimerase signature 29 45 1.2E-5 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 HRM2_RS13305 e9a4696686ac9d37c14cf3d0c9bb246e 339 Gene3D G3DSA:3.90.25.10 182 234 1.1E-52 T 22-04-2016 HRM2_RS13305 e9a4696686ac9d37c14cf3d0c9bb246e 339 Gene3D G3DSA:3.90.25.10 266 339 1.1E-52 T 22-04-2016 HRM2_RS22740 707c5f1fb2ed760926630407c4ed829e 1306 Pfam PF00691 OmpA family 1042 1133 2.4E-13 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS22740 707c5f1fb2ed760926630407c4ed829e 1306 PRINTS PR01021 OMPA domain signature 1043 1065 5.8E-6 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 HRM2_RS22740 707c5f1fb2ed760926630407c4ed829e 1306 PRINTS PR01021 OMPA domain signature 1089 1105 5.8E-6 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 HRM2_RS22740 707c5f1fb2ed760926630407c4ed829e 1306 PRINTS PR01021 OMPA domain signature 1074 1089 5.8E-6 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 HRM2_RS22740 707c5f1fb2ed760926630407c4ed829e 1306 Gene3D G3DSA:3.30.1330.60 1041 1134 1.6E-16 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS22740 707c5f1fb2ed760926630407c4ed829e 1306 SUPERFAMILY SSF103088 1039 1137 7.59E-15 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS22740 707c5f1fb2ed760926630407c4ed829e 1306 Gene3D G3DSA:1.10.150.20 91 122 2.5E-4 T 22-04-2016 HRM2_RS22740 707c5f1fb2ed760926630407c4ed829e 1306 PANTHER PTHR30128 1042 1122 1.6E-14 T 22-04-2016 HRM2_RS23855 87212ea87014b8940624fa826c4ad68d 346 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 52 326 3.4E-80 T 22-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 HRM2_RS23855 87212ea87014b8940624fa826c4ad68d 346 SUPERFAMILY SSF161111 51 244 2.22E-54 T 22-04-2016 HRM2_RS23855 87212ea87014b8940624fa826c4ad68d 346 PANTHER PTHR11562 36 332 4.1E-90 T 22-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 HRM2_RS23855 87212ea87014b8940624fa826c4ad68d 346 PANTHER PTHR11562:SF17 36 332 4.1E-90 T 22-04-2016 HRM2_RS23855 87212ea87014b8940624fa826c4ad68d 346 Pfam PF01545 Cation efflux family 53 244 2.9E-47 T 22-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 HRM2_RS23855 87212ea87014b8940624fa826c4ad68d 346 SUPERFAMILY SSF160240 249 324 9.02E-8 T 22-04-2016 HRM2_RS23855 87212ea87014b8940624fa826c4ad68d 346 Gene3D G3DSA:1.20.1510.10 51 244 6.2E-60 T 22-04-2016 IPR027469 Cation efflux protein transmembrane domain HRM2_RS03770 4ff9cb043e0a220712ec0c94eaec2eb7 416 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 22-04-2016 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 Reactome: REACT_22258 HRM2_RS03770 4ff9cb043e0a220712ec0c94eaec2eb7 416 PANTHER PTHR18919:SF95 1 416 4.0E-157 T 22-04-2016 HRM2_RS03770 4ff9cb043e0a220712ec0c94eaec2eb7 416 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 414 6.6E-128 T 22-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 HRM2_RS03770 4ff9cb043e0a220712ec0c94eaec2eb7 416 SUPERFAMILY SSF53901 3 293 5.01E-74 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS03770 4ff9cb043e0a220712ec0c94eaec2eb7 416 PANTHER PTHR18919 1 416 4.0E-157 T 22-04-2016 HRM2_RS03770 4ff9cb043e0a220712ec0c94eaec2eb7 416 PIRSF PIRSF000429 1 416 1.6E-115 T 22-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 HRM2_RS03770 4ff9cb043e0a220712ec0c94eaec2eb7 416 Pfam PF00108 Thiolase, N-terminal domain 4 149 1.8E-40 T 22-04-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 HRM2_RS03770 4ff9cb043e0a220712ec0c94eaec2eb7 416 Pfam PF00108 Thiolase, N-terminal domain 176 284 8.5E-38 T 22-04-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 HRM2_RS03770 4ff9cb043e0a220712ec0c94eaec2eb7 416 SUPERFAMILY SSF53901 294 415 1.59E-33 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS03770 4ff9cb043e0a220712ec0c94eaec2eb7 416 Gene3D G3DSA:3.40.47.10 300 415 8.5E-53 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS03770 4ff9cb043e0a220712ec0c94eaec2eb7 416 Gene3D G3DSA:3.40.47.10 175 215 8.5E-53 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS03770 4ff9cb043e0a220712ec0c94eaec2eb7 416 Gene3D G3DSA:3.40.47.10 216 299 8.6E-68 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS03770 4ff9cb043e0a220712ec0c94eaec2eb7 416 Gene3D G3DSA:3.40.47.10 3 123 8.6E-68 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS03770 4ff9cb043e0a220712ec0c94eaec2eb7 416 Pfam PF02803 Thiolase, C-terminal domain 293 414 1.0E-38 T 22-04-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 HRM2_RS22225 81766603f46856a22ec2329012a4f00a 120 PANTHER PTHR37694 5 120 2.3E-25 T 22-04-2016 HRM2_RS22225 81766603f46856a22ec2329012a4f00a 120 Gene3D G3DSA:2.60.120.10 6 113 6.9E-37 T 22-04-2016 IPR014710 RmlC-like jelly roll fold HRM2_RS22225 81766603f46856a22ec2329012a4f00a 120 Pfam PF07883 Cupin domain 45 109 6.6E-9 T 22-04-2016 IPR013096 Cupin 2, conserved barrel HRM2_RS22225 81766603f46856a22ec2329012a4f00a 120 SUPERFAMILY SSF51182 7 111 2.97E-23 T 22-04-2016 IPR011051 RmlC-like cupin domain HRM2_RS19245 8109303fa4d04a698a6d351f2ebd2b18 258 SUPERFAMILY SSF54862 40 111 1.44E-13 T 22-04-2016 HRM2_RS19245 8109303fa4d04a698a6d351f2ebd2b18 258 Pfam PF12838 4Fe-4S dicluster domain 43 91 9.2E-10 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS19245 8109303fa4d04a698a6d351f2ebd2b18 258 Gene3D G3DSA:3.30.70.20 42 104 1.1E-13 T 22-04-2016 HRM2_RS19245 8109303fa4d04a698a6d351f2ebd2b18 258 PANTHER PTHR11995:SF3 118 258 1.9E-56 T 22-04-2016 HRM2_RS19245 8109303fa4d04a698a6d351f2ebd2b18 258 Gene3D G3DSA:3.40.50.700 131 254 9.4E-27 T 22-04-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 HRM2_RS19245 8109303fa4d04a698a6d351f2ebd2b18 258 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 143 252 1.4E-23 T 22-04-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 HRM2_RS19245 8109303fa4d04a698a6d351f2ebd2b18 258 PANTHER PTHR11995 118 258 1.9E-56 T 22-04-2016 HRM2_RS19245 8109303fa4d04a698a6d351f2ebd2b18 258 SUPERFAMILY SSF56770 124 258 5.63E-48 T 22-04-2016 HRM2_RS12640 51d0346e062d1b69037573b58c338e6b 226 Pfam PF14319 Transposase zinc-binding domain 16 121 2.2E-25 T 22-04-2016 IPR026889 Transposase zinc-binding domain HRM2_RS12640 51d0346e062d1b69037573b58c338e6b 226 Pfam PF04986 Putative transposase 154 213 9.6E-7 T 22-04-2016 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 HRM2_RS04700 221d8ed7fd7873a8f167e4eb87284d41 278 SUPERFAMILY SSF54862 167 262 2.23E-8 T 22-04-2016 HRM2_RS04700 221d8ed7fd7873a8f167e4eb87284d41 278 SUPERFAMILY SSF54862 79 98 2.23E-8 T 22-04-2016 HRM2_RS04700 221d8ed7fd7873a8f167e4eb87284d41 278 PANTHER PTHR30176 1 263 3.8E-14 T 22-04-2016 HRM2_RS04700 221d8ed7fd7873a8f167e4eb87284d41 278 Pfam PF12801 4Fe-4S binding domain 171 206 7.0E-5 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS04700 221d8ed7fd7873a8f167e4eb87284d41 278 Pfam PF12801 4Fe-4S binding domain 67 111 8.6E-13 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS04700 221d8ed7fd7873a8f167e4eb87284d41 278 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 251 262 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS04700 221d8ed7fd7873a8f167e4eb87284d41 278 Gene3D G3DSA:3.30.70.20 214 263 4.8E-5 T 22-04-2016 HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 Gene3D G3DSA:3.30.450.20 80 166 5.6E-18 T 22-04-2016 HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 SMART SM00086 571 613 2.2E-4 T 22-04-2016 IPR001610 PAC motif HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 SMART SM00388 628 694 1.8E-5 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 SMART SM00091 370 433 280.0 T 22-04-2016 IPR000014 PAS domain HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 SMART SM00091 494 560 1.1E-4 T 22-04-2016 IPR000014 PAS domain HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 Gene3D G3DSA:3.30.450.20 167 286 2.9E-4 T 22-04-2016 HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 Pfam PF00512 His Kinase A (phospho-acceptor) domain 632 692 5.1E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 PRINTS PR00344 Bacterial sensor protein C-terminal signature 783 797 4.1E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 PRINTS PR00344 Bacterial sensor protein C-terminal signature 812 830 4.1E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 PRINTS PR00344 Bacterial sensor protein C-terminal signature 801 811 4.1E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 PRINTS PR00344 Bacterial sensor protein C-terminal signature 836 849 4.1E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 SUPERFAMILY SSF55785 478 608 4.19E-20 T 22-04-2016 IPR000014 PAS domain HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 491 620 5.9E-15 T 22-04-2016 IPR000014 PAS domain HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 PANTHER PTHR24423:SF458 478 990 2.8E-113 T 22-04-2016 HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 PANTHER PTHR24423:SF458 7 17 2.8E-113 T 22-04-2016 HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 SMART SM00448 871 988 9.9E-18 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 SMART SM00387 733 852 1.0E-32 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 Gene3D G3DSA:3.30.565.10 700 850 3.2E-40 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 Pfam PF00072 Response regulator receiver domain 873 988 2.4E-14 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 Pfam PF13426 PAS domain 85 174 1.7 T 22-04-2016 IPR000014 PAS domain HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 Pfam PF13426 PAS domain 387 481 0.02 T 22-04-2016 IPR000014 PAS domain HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 Gene3D G3DSA:3.30.450.20 363 479 1.9E-5 T 22-04-2016 HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 Gene3D G3DSA:3.30.450.20 480 611 6.7E-20 T 22-04-2016 HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 SUPERFAMILY SSF52172 869 993 3.56E-23 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 Pfam PF02743 Cache domain 45 262 9.2E-19 T 22-04-2016 IPR033479 Double Cache domain 1 HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 734 850 8.8E-22 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 SUPERFAMILY SSF55874 700 849 2.75E-37 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 PANTHER PTHR24423 478 990 2.8E-113 T 22-04-2016 HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 PANTHER PTHR24423 7 17 2.8E-113 T 22-04-2016 HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 Gene3D G3DSA:3.40.50.2300 866 993 1.5E-23 T 22-04-2016 HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 Pfam PF08448 PAS fold 500 613 3.2E-14 T 22-04-2016 IPR013656 PAS fold-4 HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 SUPERFAMILY SSF47384 624 691 2.16E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 SUPERFAMILY SSF158472 312 358 3.4E-5 T 22-04-2016 HRM2_RS24885 41b2d2cc2f7fb0cd05a4977b016b17b6 998 Pfam PF00672 HAMP domain 290 358 1.1E-9 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS09100 a7532f4f39c82372693eefd8cdf04a4e 228 Gene3D G3DSA:1.10.510.10 142 198 2.7E-10 T 22-04-2016 HRM2_RS09100 a7532f4f39c82372693eefd8cdf04a4e 228 SUPERFAMILY SSF56112 58 199 9.85E-14 T 22-04-2016 IPR011009 Protein kinase-like domain HRM2_RS09100 a7532f4f39c82372693eefd8cdf04a4e 228 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 46 196 4.4E-19 T 22-04-2016 IPR010440 Lipopolysaccharide kinase GO:0005524|GO:0016020|GO:0016773 HRM2_RS20360 320aecdec57346a22d018286c1256f61 248 PANTHER PTHR24220 3 238 1.0E-120 T 22-04-2016 HRM2_RS20360 320aecdec57346a22d018286c1256f61 248 SMART SM00382 26 216 4.2E-5 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS20360 320aecdec57346a22d018286c1256f61 248 SUPERFAMILY SSF52540 2 237 6.18E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20360 320aecdec57346a22d018286c1256f61 248 Gene3D G3DSA:3.40.50.300 1 233 1.3E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20360 320aecdec57346a22d018286c1256f61 248 Pfam PF00005 ABC transporter 18 165 9.1E-30 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS20360 320aecdec57346a22d018286c1256f61 248 PIRSF PIRSF039137 1 238 2.4E-103 T 22-04-2016 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 HRM2_RS20360 320aecdec57346a22d018286c1256f61 248 PANTHER PTHR24220:SF568 3 238 1.0E-120 T 22-04-2016 HRM2_RS20360 320aecdec57346a22d018286c1256f61 248 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS06415 7963421073e84c277975143c5d2a0fe1 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 303 1.5E-41 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS06415 7963421073e84c277975143c5d2a0fe1 305 PANTHER PTHR30465 1 304 9.2E-113 T 22-04-2016 HRM2_RS06415 7963421073e84c277975143c5d2a0fe1 305 SUPERFAMILY SSF161098 90 286 3.66E-25 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS06415 7963421073e84c277975143c5d2a0fe1 305 PANTHER PTHR30465:SF24 1 304 9.2E-113 T 22-04-2016 HRM2_RS06415 7963421073e84c277975143c5d2a0fe1 305 Gene3D G3DSA:1.10.3720.10 92 300 9.3E-25 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS24055 d163f66d1bee3e26770b1534b9999737 653 PANTHER PTHR10108 585 653 8.8E-112 T 22-04-2016 HRM2_RS24055 d163f66d1bee3e26770b1534b9999737 653 PANTHER PTHR10108 312 567 8.8E-112 T 22-04-2016 HRM2_RS24055 d163f66d1bee3e26770b1534b9999737 653 Pfam PF02353 Mycolic acid cyclopropane synthetase 383 649 8.9E-79 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS24055 d163f66d1bee3e26770b1534b9999737 653 PANTHER PTHR10108:SF795 585 653 8.8E-112 T 22-04-2016 HRM2_RS24055 d163f66d1bee3e26770b1534b9999737 653 PANTHER PTHR10108:SF795 312 567 8.8E-112 T 22-04-2016 HRM2_RS24055 d163f66d1bee3e26770b1534b9999737 653 Gene3D G3DSA:3.40.50.150 375 651 2.3E-97 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS24055 d163f66d1bee3e26770b1534b9999737 653 Pfam PF07103 Protein of unknown function (DUF1365) 5 247 2.7E-67 T 22-04-2016 IPR010775 Protein of unknown function DUF1365 HRM2_RS24055 d163f66d1bee3e26770b1534b9999737 653 SUPERFAMILY SSF53335 387 652 8.28E-73 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS21705 22868a59e9f823959a366257829bd517 122 SUPERFAMILY SSF50118 6 120 1.29E-27 T 22-04-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor HRM2_RS21705 22868a59e9f823959a366257829bd517 122 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 8 118 9.4E-23 T 22-04-2016 IPR003477 mRNA interferase PemK-like protein GO:0003677 HRM2_RS21705 22868a59e9f823959a366257829bd517 122 Gene3D G3DSA:2.30.30.110 8 118 3.2E-28 T 22-04-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor HRM2_RS21705 22868a59e9f823959a366257829bd517 122 PIRSF PIRSF033490 5 120 4.1E-32 T 22-04-2016 IPR003477 mRNA interferase PemK-like protein GO:0003677 HRM2_RS21705 22868a59e9f823959a366257829bd517 122 PANTHER PTHR33988 2 122 8.9E-26 T 22-04-2016 HRM2_RS01485 b859a0ee57e94c727e974d9347940f6e 240 Pfam PF00440 Bacterial regulatory proteins, tetR family 44 88 3.6E-10 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS01485 b859a0ee57e94c727e974d9347940f6e 240 SUPERFAMILY SSF46689 38 115 6.98E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS01485 b859a0ee57e94c727e974d9347940f6e 240 SUPERFAMILY SSF48498 111 222 2.0E-12 T 22-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal HRM2_RS01485 b859a0ee57e94c727e974d9347940f6e 240 Gene3D G3DSA:1.10.357.10 86 220 1.1E-17 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HRM2_RS01485 b859a0ee57e94c727e974d9347940f6e 240 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 57 2.5E-5 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS01485 b859a0ee57e94c727e974d9347940f6e 240 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 65 88 2.5E-5 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS01485 b859a0ee57e94c727e974d9347940f6e 240 Gene3D G3DSA:1.10.10.60 43 85 2.0E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS01485 b859a0ee57e94c727e974d9347940f6e 240 PANTHER PTHR30055 27 221 7.9E-19 T 22-04-2016 HRM2_RS12055 749d89612aae486a2f444fc8ad9070a8 458 PANTHER PTHR11819 29 433 1.0E-29 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 HRM2_RS12055 749d89612aae486a2f444fc8ad9070a8 458 Pfam PF00474 Sodium:solute symporter family 61 403 5.2E-15 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 HRM2_RS23320 277350586ee750250df2bd2aad98a3f3 253 Gene3D G3DSA:3.30.70.20 141 193 1.6E-29 T 22-04-2016 HRM2_RS23320 277350586ee750250df2bd2aad98a3f3 253 Gene3D G3DSA:3.30.70.20 5 82 1.6E-29 T 22-04-2016 HRM2_RS23320 277350586ee750250df2bd2aad98a3f3 253 Pfam PF13247 4Fe-4S dicluster domain 67 170 5.2E-39 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS23320 277350586ee750250df2bd2aad98a3f3 253 PANTHER PTHR11938 1 38 4.7E-28 T 22-04-2016 HRM2_RS23320 277350586ee750250df2bd2aad98a3f3 253 PANTHER PTHR11938 62 173 4.7E-28 T 22-04-2016 HRM2_RS23320 277350586ee750250df2bd2aad98a3f3 253 SUPERFAMILY SSF54862 4 196 4.03E-38 T 22-04-2016 HRM2_RS23320 277350586ee750250df2bd2aad98a3f3 253 Gene3D G3DSA:3.30.70.20 83 140 5.4E-17 T 22-04-2016 HRM2_RS23320 277350586ee750250df2bd2aad98a3f3 253 PANTHER PTHR11938:SF88 1 38 4.7E-28 T 22-04-2016 HRM2_RS23320 277350586ee750250df2bd2aad98a3f3 253 PANTHER PTHR11938:SF88 62 173 4.7E-28 T 22-04-2016 HRM2_RS10985 3b7c99dc41ad287368cb664536123fd1 591 Gene3D G3DSA:1.10.3080.10 14 426 2.5E-80 T 22-04-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 HRM2_RS10985 3b7c99dc41ad287368cb664536123fd1 591 PANTHER PTHR11689 15 588 2.3E-103 T 22-04-2016 HRM2_RS10985 3b7c99dc41ad287368cb664536123fd1 591 SMART SM00116 467 515 1.6 T 22-04-2016 IPR000644 CBS domain HRM2_RS10985 3b7c99dc41ad287368cb664536123fd1 591 SMART SM00116 532 582 3.5E-4 T 22-04-2016 IPR000644 CBS domain HRM2_RS10985 3b7c99dc41ad287368cb664536123fd1 591 SUPERFAMILY SSF81340 12 444 8.5E-104 T 22-04-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 HRM2_RS10985 3b7c99dc41ad287368cb664536123fd1 591 Gene3D G3DSA:3.10.580.10 457 581 6.1E-19 T 22-04-2016 HRM2_RS10985 3b7c99dc41ad287368cb664536123fd1 591 PRINTS PR00762 Chloride channel signature 125 144 2.3E-23 T 22-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HRM2_RS10985 3b7c99dc41ad287368cb664536123fd1 591 PRINTS PR00762 Chloride channel signature 176 195 2.3E-23 T 22-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HRM2_RS10985 3b7c99dc41ad287368cb664536123fd1 591 PRINTS PR00762 Chloride channel signature 394 413 2.3E-23 T 22-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HRM2_RS10985 3b7c99dc41ad287368cb664536123fd1 591 PRINTS PR00762 Chloride channel signature 341 361 2.3E-23 T 22-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HRM2_RS10985 3b7c99dc41ad287368cb664536123fd1 591 PRINTS PR00762 Chloride channel signature 376 392 2.3E-23 T 22-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HRM2_RS10985 3b7c99dc41ad287368cb664536123fd1 591 Pfam PF00571 CBS domain 526 579 3.9E-8 T 22-04-2016 IPR000644 CBS domain HRM2_RS10985 3b7c99dc41ad287368cb664536123fd1 591 Pfam PF00571 CBS domain 465 514 1.4E-5 T 22-04-2016 IPR000644 CBS domain HRM2_RS10985 3b7c99dc41ad287368cb664536123fd1 591 Pfam PF00654 Voltage gated chloride channel 83 425 4.2E-89 T 22-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HRM2_RS10985 3b7c99dc41ad287368cb664536123fd1 591 SUPERFAMILY SSF54631 447 580 4.36E-23 T 22-04-2016 HRM2_RS10985 3b7c99dc41ad287368cb664536123fd1 591 PANTHER PTHR11689:SF14 15 588 2.3E-103 T 22-04-2016 HRM2_RS24425 3130f3e26043ac0c92b7a33febcfe722 264 PANTHER PTHR34183 53 264 1.3E-65 T 22-04-2016 HRM2_RS24425 3130f3e26043ac0c92b7a33febcfe722 264 SUPERFAMILY SSF110997 189 262 1.96E-13 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 HRM2_RS24425 3130f3e26043ac0c92b7a33febcfe722 264 Gene3D G3DSA:3.30.70.1070 188 260 8.6E-12 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 HRM2_RS24425 3130f3e26043ac0c92b7a33febcfe722 264 PANTHER PTHR34183:SF1 53 264 1.3E-65 T 22-04-2016 HRM2_RS24425 3130f3e26043ac0c92b7a33febcfe722 264 Gene3D G3DSA:2.40.40.10 110 161 1.4E-4 T 22-04-2016 IPR009009 RlpA-like protein, double-psi beta-barrel domain HRM2_RS24425 3130f3e26043ac0c92b7a33febcfe722 264 Pfam PF03330 Lytic transglycolase 73 162 1.5E-28 T 22-04-2016 IPR009009 RlpA-like protein, double-psi beta-barrel domain HRM2_RS24425 3130f3e26043ac0c92b7a33febcfe722 264 Pfam PF05036 Sporulation related domain 189 262 5.5E-15 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 HRM2_RS24425 3130f3e26043ac0c92b7a33febcfe722 264 SUPERFAMILY SSF50685 70 162 2.34E-13 T 22-04-2016 IPR009009 RlpA-like protein, double-psi beta-barrel domain HRM2_RS24425 3130f3e26043ac0c92b7a33febcfe722 264 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 75 169 2.1E-46 T 22-04-2016 IPR012997 Rare lipoprotein A HRM2_RS15305 84d05c7ade926aab9e7b414d9b7dd33a 76 PANTHER PTHR34654 1 76 4.6E-28 T 22-04-2016 HRM2_RS15305 84d05c7ade926aab9e7b414d9b7dd33a 76 Pfam PF13083 KH domain 2 74 4.8E-23 T 22-04-2016 HRM2_RS15305 84d05c7ade926aab9e7b414d9b7dd33a 76 Hamap MF_00088 UPF0109 protein . 1 75 22.598 T 22-04-2016 IPR020627 Uncharacterised protein family UPF0109 HRM2_RS15305 84d05c7ade926aab9e7b414d9b7dd33a 76 SUPERFAMILY SSF54814 4 61 2.29E-6 T 22-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 HRM2_RS15305 84d05c7ade926aab9e7b414d9b7dd33a 76 Gene3D G3DSA:3.30.300.20 4 57 2.7E-5 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta HRM2_RS03605 1f99ef81ad17e14c6708120708a53ba3 123 Pfam PF01807 CHC2 zinc finger 10 91 2.7E-6 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS03605 1f99ef81ad17e14c6708120708a53ba3 123 Gene3D G3DSA:3.90.580.10 5 99 2.4E-13 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS03605 1f99ef81ad17e14c6708120708a53ba3 123 SUPERFAMILY SSF57783 13 92 1.51E-10 T 22-04-2016 HRM2_RS10245 1f99ef81ad17e14c6708120708a53ba3 123 Pfam PF01807 CHC2 zinc finger 10 91 2.7E-6 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS10245 1f99ef81ad17e14c6708120708a53ba3 123 Gene3D G3DSA:3.90.580.10 5 99 2.4E-13 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS10245 1f99ef81ad17e14c6708120708a53ba3 123 SUPERFAMILY SSF57783 13 92 1.51E-10 T 22-04-2016 HRM2_RS03925 1f99ef81ad17e14c6708120708a53ba3 123 Pfam PF01807 CHC2 zinc finger 10 91 2.7E-6 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS03925 1f99ef81ad17e14c6708120708a53ba3 123 Gene3D G3DSA:3.90.580.10 5 99 2.4E-13 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS03925 1f99ef81ad17e14c6708120708a53ba3 123 SUPERFAMILY SSF57783 13 92 1.51E-10 T 22-04-2016 HRM2_RS11850 1f99ef81ad17e14c6708120708a53ba3 123 Pfam PF01807 CHC2 zinc finger 10 91 2.7E-6 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS11850 1f99ef81ad17e14c6708120708a53ba3 123 Gene3D G3DSA:3.90.580.10 5 99 2.4E-13 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS11850 1f99ef81ad17e14c6708120708a53ba3 123 SUPERFAMILY SSF57783 13 92 1.51E-10 T 22-04-2016 HRM2_RS03165 1f99ef81ad17e14c6708120708a53ba3 123 Pfam PF01807 CHC2 zinc finger 10 91 2.7E-6 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS03165 1f99ef81ad17e14c6708120708a53ba3 123 Gene3D G3DSA:3.90.580.10 5 99 2.4E-13 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS03165 1f99ef81ad17e14c6708120708a53ba3 123 SUPERFAMILY SSF57783 13 92 1.51E-10 T 22-04-2016 HRM2_RS04675 1f99ef81ad17e14c6708120708a53ba3 123 Pfam PF01807 CHC2 zinc finger 10 91 2.7E-6 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS04675 1f99ef81ad17e14c6708120708a53ba3 123 Gene3D G3DSA:3.90.580.10 5 99 2.4E-13 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS04675 1f99ef81ad17e14c6708120708a53ba3 123 SUPERFAMILY SSF57783 13 92 1.51E-10 T 22-04-2016 HRM2_RS16965 1f99ef81ad17e14c6708120708a53ba3 123 Pfam PF01807 CHC2 zinc finger 10 91 2.7E-6 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS16965 1f99ef81ad17e14c6708120708a53ba3 123 Gene3D G3DSA:3.90.580.10 5 99 2.4E-13 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS16965 1f99ef81ad17e14c6708120708a53ba3 123 SUPERFAMILY SSF57783 13 92 1.51E-10 T 22-04-2016 HRM2_RS16925 41c98e747995f021af316a4d8b0166c1 360 Pfam PF00072 Response regulator receiver domain 14 122 7.0E-27 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS16925 41c98e747995f021af316a4d8b0166c1 360 Gene3D G3DSA:3.40.50.2300 13 143 5.7E-37 T 22-04-2016 HRM2_RS16925 41c98e747995f021af316a4d8b0166c1 360 SUPERFAMILY SSF52172 9 144 3.84E-36 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS16925 41c98e747995f021af316a4d8b0166c1 360 Gene3D G3DSA:1.10.3210.10 160 331 2.5E-24 T 22-04-2016 IPR006674 HD domain HRM2_RS16925 41c98e747995f021af316a4d8b0166c1 360 Pfam PF01966 HD domain 165 287 7.4E-19 T 22-04-2016 IPR006674 HD domain HRM2_RS16925 41c98e747995f021af316a4d8b0166c1 360 PANTHER PTHR26402 12 158 3.3E-36 T 22-04-2016 HRM2_RS16925 41c98e747995f021af316a4d8b0166c1 360 SMART SM00448 12 122 3.2E-31 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS16925 41c98e747995f021af316a4d8b0166c1 360 SUPERFAMILY SSF109604 151 326 5.34E-40 T 22-04-2016 HRM2_RS16925 41c98e747995f021af316a4d8b0166c1 360 SMART SM00471 160 297 6.4E-7 T 22-04-2016 IPR003607 HD/PDEase domain HRM2_RS17120 86dd592680f1eb94b1611a46a39e6325 525 Pfam PF00158 Sigma-54 interaction domain 198 365 3.1E-70 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS17120 86dd592680f1eb94b1611a46a39e6325 525 Gene3D G3DSA:1.10.10.60 422 512 9.9E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS17120 86dd592680f1eb94b1611a46a39e6325 525 Gene3D G3DSA:1.10.8.60 371 421 1.2E-18 T 22-04-2016 HRM2_RS17120 86dd592680f1eb94b1611a46a39e6325 525 SMART SM00382 218 362 4.6E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS17120 86dd592680f1eb94b1611a46a39e6325 525 Gene3D G3DSA:3.30.450.40 4 172 6.1E-6 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS17120 86dd592680f1eb94b1611a46a39e6325 525 SUPERFAMILY SSF52540 198 429 2.41E-63 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17120 86dd592680f1eb94b1611a46a39e6325 525 Gene3D G3DSA:3.40.50.300 197 370 3.6E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17120 86dd592680f1eb94b1611a46a39e6325 525 SUPERFAMILY SSF55781 2 179 5.89E-9 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS17120 86dd592680f1eb94b1611a46a39e6325 525 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 222 235 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS17120 86dd592680f1eb94b1611a46a39e6325 525 PANTHER PTHR32071 141 523 1.5E-138 T 22-04-2016 HRM2_RS17120 86dd592680f1eb94b1611a46a39e6325 525 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 412 421 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS17120 86dd592680f1eb94b1611a46a39e6325 525 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 284 299 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS09555 aea718bfa2a07709237fbbeb020ceff5 246 SUPERFAMILY SSF52540 82 221 1.26E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09555 aea718bfa2a07709237fbbeb020ceff5 246 PANTHER PTHR30050:SF6 4 231 1.7E-29 T 22-04-2016 HRM2_RS09555 aea718bfa2a07709237fbbeb020ceff5 246 PANTHER PTHR30050 4 231 1.7E-29 T 22-04-2016 HRM2_RS09555 aea718bfa2a07709237fbbeb020ceff5 246 PIRSF PIRSF003073 1 245 4.9E-59 T 22-04-2016 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein HRM2_RS09555 aea718bfa2a07709237fbbeb020ceff5 246 Gene3D G3DSA:3.40.50.300 54 230 1.5E-22 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09555 aea718bfa2a07709237fbbeb020ceff5 246 Pfam PF01695 IstB-like ATP binding protein 57 229 1.1E-38 T 22-04-2016 IPR002611 IstB-like ATP-binding protein GO:0005524 HRM2_RS06685 deab74f90264f9abdbce94d725384b43 175 Pfam PF03266 NTPase 2 158 3.3E-19 T 22-04-2016 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 HRM2_RS06685 deab74f90264f9abdbce94d725384b43 175 Gene3D G3DSA:3.40.50.300 3 49 1.6E-4 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06685 deab74f90264f9abdbce94d725384b43 175 SUPERFAMILY SSF52540 2 168 1.38E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22760 318342266ec02bd648772db99325638b 349 Pfam PF12698 ABC-2 family transporter protein 26 341 2.3E-25 T 22-04-2016 HRM2_RS22760 318342266ec02bd648772db99325638b 349 PANTHER PTHR30294 1 347 8.6E-36 T 22-04-2016 HRM2_RS18380 d09efe044a80efea1bd3952dcb5e8ed0 152 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 6 142 7.1E-17 T 22-04-2016 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 HRM2_RS18380 d09efe044a80efea1bd3952dcb5e8ed0 152 Pfam PF02050 Flagellar FliJ protein 21 141 6.3E-13 T 22-04-2016 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 HRM2_RS21185 74a193cd9e8bdeaa2f30e79d11ce49b8 372 Gene3D G3DSA:2.40.370.10 56 240 3.7E-65 T 22-04-2016 IPR023374 AttH-like domain HRM2_RS21185 74a193cd9e8bdeaa2f30e79d11ce49b8 372 SUPERFAMILY SSF159245 45 369 8.11E-95 T 22-04-2016 HRM2_RS21185 74a193cd9e8bdeaa2f30e79d11ce49b8 372 PANTHER PTHR38591 1 372 1.5E-103 T 22-04-2016 HRM2_RS21185 74a193cd9e8bdeaa2f30e79d11ce49b8 372 Pfam PF17186 Lipocalin-like domain 244 369 4.3E-40 T 22-04-2016 IPR033451 AttH, lipocalin-like domain HRM2_RS21185 74a193cd9e8bdeaa2f30e79d11ce49b8 372 Pfam PF07143 CrtC N-terminal lipocalin domain 68 239 4.1E-58 T 22-04-2016 IPR010791 AttH domain HRM2_RS21185 74a193cd9e8bdeaa2f30e79d11ce49b8 372 Gene3D G3DSA:2.40.370.10 245 370 1.8E-37 T 22-04-2016 IPR023374 AttH-like domain HRM2_RS13530 5d7cb4984bb027d842ba88a868f9279a 343 PANTHER PTHR30465 1 342 8.6E-121 T 22-04-2016 HRM2_RS13530 5d7cb4984bb027d842ba88a868f9279a 343 Gene3D G3DSA:1.10.3720.10 113 330 6.3E-13 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS13530 5d7cb4984bb027d842ba88a868f9279a 343 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 136 341 2.0E-30 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS13530 5d7cb4984bb027d842ba88a868f9279a 343 SUPERFAMILY SSF161098 111 324 8.63E-13 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS13530 5d7cb4984bb027d842ba88a868f9279a 343 PANTHER PTHR30465:SF66 1 342 8.6E-121 T 22-04-2016 HRM2_RS01230 ed7d8d32f1c6b82ee715f3f19a4b63ac 263 PIRSF PIRSF000388 1 263 1.4E-110 T 22-04-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 HRM2_RS01230 ed7d8d32f1c6b82ee715f3f19a4b63ac 263 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 6 263 1.1E-97 T 22-04-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 HRM2_RS01230 ed7d8d32f1c6b82ee715f3f19a4b63ac 263 SUPERFAMILY SSF51621 4 262 7.85E-104 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HRM2_RS01230 ed7d8d32f1c6b82ee715f3f19a4b63ac 263 Pfam PF02548 Ketopantoate hydroxymethyltransferase 4 257 7.4E-112 T 22-04-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 HRM2_RS01230 ed7d8d32f1c6b82ee715f3f19a4b63ac 263 PANTHER PTHR20881 4 263 1.4E-148 T 22-04-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 HRM2_RS01230 ed7d8d32f1c6b82ee715f3f19a4b63ac 263 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 5 262 42.82 T 22-04-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 HRM2_RS01230 ed7d8d32f1c6b82ee715f3f19a4b63ac 263 Gene3D G3DSA:3.20.20.60 4 263 3.3E-113 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HRM2_RS19670 8b4e5968d5897103fc92868b1030a159 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 6.2E-20 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS19670 8b4e5968d5897103fc92868b1030a159 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 6.2E-20 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS19670 8b4e5968d5897103fc92868b1030a159 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 6.2E-20 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS19670 8b4e5968d5897103fc92868b1030a159 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 6.2E-20 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS19670 8b4e5968d5897103fc92868b1030a159 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 6.2E-20 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS19670 8b4e5968d5897103fc92868b1030a159 259 Gene3D G3DSA:3.40.50.720 5 224 1.7E-56 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS19670 8b4e5968d5897103fc92868b1030a159 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 2.7E-8 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS19670 8b4e5968d5897103fc92868b1030a159 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 2.7E-8 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS19670 8b4e5968d5897103fc92868b1030a159 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.7E-8 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS19670 8b4e5968d5897103fc92868b1030a159 259 PANTHER PTHR24322 9 136 1.6E-39 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS19670 8b4e5968d5897103fc92868b1030a159 259 PANTHER PTHR24322 152 177 1.6E-39 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS19670 8b4e5968d5897103fc92868b1030a159 259 SUPERFAMILY SSF51735 4 253 1.11E-56 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS19670 8b4e5968d5897103fc92868b1030a159 259 Pfam PF00106 short chain dehydrogenase 5 193 6.7E-44 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS21740 489c29bf4ad1f9de2226f7cd303b40f8 619 SUPERFAMILY SSF56228 1 208 9.42E-63 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS21740 489c29bf4ad1f9de2226f7cd303b40f8 619 SUPERFAMILY SSF48310 215 618 9.81E-99 T 22-04-2016 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS21740 489c29bf4ad1f9de2226f7cd303b40f8 619 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 234 616 7.2E-104 T 22-04-2016 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS21740 489c29bf4ad1f9de2226f7cd303b40f8 619 Gene3D G3DSA:3.60.9.10 4 208 9.0E-70 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS21740 489c29bf4ad1f9de2226f7cd303b40f8 619 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 7 205 2.2E-65 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS21740 489c29bf4ad1f9de2226f7cd303b40f8 619 SMART SM00790 4 207 2.2E-87 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS21740 489c29bf4ad1f9de2226f7cd303b40f8 619 PANTHER PTHR30038 1 619 1.1E-180 T 22-04-2016 HRM2_RS21740 489c29bf4ad1f9de2226f7cd303b40f8 619 PANTHER PTHR30038:SF0 1 619 1.1E-180 T 22-04-2016 HRM2_RS21740 489c29bf4ad1f9de2226f7cd303b40f8 619 Gene3D G3DSA:1.10.569.10 241 427 1.7E-56 T 22-04-2016 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 HRM2_RS14560 5900aca83d885b39b62cb40f66015642 179 Gene3D G3DSA:3.40.50.850 3 179 2.2E-53 T 22-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 HRM2_RS14560 5900aca83d885b39b62cb40f66015642 179 SUPERFAMILY SSF52499 2 179 6.02E-44 T 22-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 HRM2_RS14560 5900aca83d885b39b62cb40f66015642 179 Pfam PF00857 Isochorismatase family 7 154 6.2E-25 T 22-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 HRM2_RS14560 5900aca83d885b39b62cb40f66015642 179 PANTHER PTHR14119 1 179 3.8E-53 T 22-04-2016 HRM2_RS03760 919cc6ae1523502469b40b288acd71a8 258 Gene3D G3DSA:3.40.50.1400 1 138 4.8E-25 T 22-04-2016 HRM2_RS03760 919cc6ae1523502469b40b288acd71a8 258 SUPERFAMILY SSF53800 2 250 1.7E-55 T 22-04-2016 HRM2_RS03760 919cc6ae1523502469b40b288acd71a8 258 Gene3D G3DSA:3.40.50.1400 139 250 1.9E-11 T 22-04-2016 HRM2_RS03760 919cc6ae1523502469b40b288acd71a8 258 Pfam PF06180 Cobalt chelatase (CbiK) 5 250 5.8E-54 T 22-04-2016 IPR010388 Anaerobic cobalt chelatase GO:0016852|GO:0019251 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 HRM2_RS03760 919cc6ae1523502469b40b288acd71a8 258 PIRSF PIRSF033579 1 254 7.8E-59 T 22-04-2016 IPR010388 Anaerobic cobalt chelatase GO:0016852|GO:0019251 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 HRM2_RS04495 b00f7f779d621f4433b9a4ae79799390 496 PANTHER PTHR10366 279 342 2.5E-73 T 22-04-2016 HRM2_RS04495 b00f7f779d621f4433b9a4ae79799390 496 PANTHER PTHR10366 23 258 2.5E-73 T 22-04-2016 HRM2_RS04495 b00f7f779d621f4433b9a4ae79799390 496 Gene3D G3DSA:3.40.50.720 17 242 1.7E-38 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS04495 b00f7f779d621f4433b9a4ae79799390 496 PANTHER PTHR10366:SF401 279 342 2.5E-73 T 22-04-2016 HRM2_RS04495 b00f7f779d621f4433b9a4ae79799390 496 PANTHER PTHR10366:SF401 23 258 2.5E-73 T 22-04-2016 HRM2_RS04495 b00f7f779d621f4433b9a4ae79799390 496 Pfam PF13460 NAD(P)H-binding 28 164 4.0E-14 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS04495 b00f7f779d621f4433b9a4ae79799390 496 SUPERFAMILY SSF51735 23 314 4.33E-46 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS04495 b00f7f779d621f4433b9a4ae79799390 496 Pfam PF11066 Protein of unknown function (DUF2867) 351 486 1.8E-27 T 22-04-2016 IPR021295 Protein of unknown function DUF2867 HRM2_RS08865 bb1727cdd1ea2989cacd2f9b8df2bf56 578 Pfam PF01435 Peptidase family M48 233 377 6.3E-13 T 22-04-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 HRM2_RS08865 bb1727cdd1ea2989cacd2f9b8df2bf56 578 SUPERFAMILY SSF48452 449 568 4.96E-14 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS08865 bb1727cdd1ea2989cacd2f9b8df2bf56 578 Gene3D G3DSA:3.30.2010.10 198 271 5.5E-11 T 22-04-2016 HRM2_RS08865 bb1727cdd1ea2989cacd2f9b8df2bf56 578 SMART SM00028 460 493 1.0E-5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS08865 bb1727cdd1ea2989cacd2f9b8df2bf56 578 Gene3D G3DSA:1.25.40.10 449 569 1.2E-16 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS20220 6331189ab57a982903d7749d256ecd54 262 PANTHER PTHR22748 2 260 5.4E-117 T 22-04-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 HRM2_RS20220 6331189ab57a982903d7749d256ecd54 262 SUPERFAMILY SSF56219 6 261 5.76E-78 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase HRM2_RS20220 6331189ab57a982903d7749d256ecd54 262 ProSitePatterns PS00727 AP endonucleases family 1 signature 2. 194 209 - T 22-04-2016 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 HRM2_RS20220 6331189ab57a982903d7749d256ecd54 262 Gene3D G3DSA:3.60.10.10 3 260 1.3E-97 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase HRM2_RS20220 6331189ab57a982903d7749d256ecd54 262 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 6 260 3.6E-87 T 22-04-2016 HRM2_RS20220 6331189ab57a982903d7749d256ecd54 262 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 9 253 2.4E-28 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase HRM2_RS20220 6331189ab57a982903d7749d256ecd54 262 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 6 260 3.0E-91 T 22-04-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 HRM2_RS20220 6331189ab57a982903d7749d256ecd54 262 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 33 42 - T 22-04-2016 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 HRM2_RS07020 2c2dcd3ce2c38caf11f7894ed636fac9 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 30 46 4.9E-34 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS07020 2c2dcd3ce2c38caf11f7894ed636fac9 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 91 104 4.9E-34 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS07020 2c2dcd3ce2c38caf11f7894ed636fac9 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 75 89 4.9E-34 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS07020 2c2dcd3ce2c38caf11f7894ed636fac9 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 167 186 4.9E-34 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS07020 2c2dcd3ce2c38caf11f7894ed636fac9 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 148 162 4.9E-34 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS07020 2c2dcd3ce2c38caf11f7894ed636fac9 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 252 271 4.9E-34 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS07020 2c2dcd3ce2c38caf11f7894ed636fac9 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 122 138 4.9E-34 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS07020 2c2dcd3ce2c38caf11f7894ed636fac9 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 297 323 4.9E-34 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS07020 2c2dcd3ce2c38caf11f7894ed636fac9 351 PIRSF PIRSF019574 1 351 1.6E-103 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HRM2_RS07020 2c2dcd3ce2c38caf11f7894ed636fac9 351 SUPERFAMILY SSF53850 26 349 3.11E-77 T 22-04-2016 HRM2_RS07020 2c2dcd3ce2c38caf11f7894ed636fac9 351 PANTHER PTHR30222:SF5 1 350 8.6E-88 T 22-04-2016 HRM2_RS07020 2c2dcd3ce2c38caf11f7894ed636fac9 351 Pfam PF13416 Bacterial extracellular solute-binding protein 43 306 1.1E-36 T 22-04-2016 HRM2_RS07020 2c2dcd3ce2c38caf11f7894ed636fac9 351 Gene3D G3DSA:3.40.190.10 142 302 9.1E-49 T 22-04-2016 HRM2_RS07020 2c2dcd3ce2c38caf11f7894ed636fac9 351 PANTHER PTHR30222 1 350 8.6E-88 T 22-04-2016 HRM2_RS07020 2c2dcd3ce2c38caf11f7894ed636fac9 351 Gene3D G3DSA:3.40.190.10 27 141 8.6E-20 T 22-04-2016 HRM2_RS00410 14dd0aad6441249c626b928eea864984 232 SMART SM00419 173 221 6.8E-15 T 22-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HRM2_RS00410 14dd0aad6441249c626b928eea864984 232 Pfam PF13545 Crp-like helix-turn-helix domain 154 226 1.4E-17 T 22-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HRM2_RS00410 14dd0aad6441249c626b928eea864984 232 SUPERFAMILY SSF51206 11 146 2.62E-28 T 22-04-2016 IPR018490 Cyclic nucleotide-binding-like HRM2_RS00410 14dd0aad6441249c626b928eea864984 232 SMART SM00100 16 134 2.1E-14 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain HRM2_RS00410 14dd0aad6441249c626b928eea864984 232 Gene3D G3DSA:1.10.10.10 152 229 1.4E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS00410 14dd0aad6441249c626b928eea864984 232 PANTHER PTHR24567:SF32 6 230 3.7E-49 T 22-04-2016 HRM2_RS00410 14dd0aad6441249c626b928eea864984 232 Pfam PF00027 Cyclic nucleotide-binding domain 37 121 2.6E-13 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain HRM2_RS00410 14dd0aad6441249c626b928eea864984 232 Gene3D G3DSA:2.60.120.10 12 144 9.7E-27 T 22-04-2016 IPR014710 RmlC-like jelly roll fold HRM2_RS00410 14dd0aad6441249c626b928eea864984 232 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 179 195 1.6E-5 T 22-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HRM2_RS00410 14dd0aad6441249c626b928eea864984 232 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 195 210 1.6E-5 T 22-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HRM2_RS00410 14dd0aad6441249c626b928eea864984 232 SUPERFAMILY SSF46785 152 229 6.82E-20 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS00410 14dd0aad6441249c626b928eea864984 232 PANTHER PTHR24567 6 230 3.7E-49 T 22-04-2016 HRM2_RS10425 1d866b16dce1aac22ec5709ce920e4cc 490 PANTHER PTHR21371 1 490 1.9E-178 T 22-04-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HRM2_RS10425 1d866b16dce1aac22ec5709ce920e4cc 490 SUPERFAMILY SSF51735 31 208 2.02E-57 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS10425 1d866b16dce1aac22ec5709ce920e4cc 490 Gene3D G3DSA:3.40.50.720 3 201 4.9E-68 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS10425 1d866b16dce1aac22ec5709ce920e4cc 490 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 35 204 6.9E-59 T 22-04-2016 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HRM2_RS10425 1d866b16dce1aac22ec5709ce920e4cc 490 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 35 368 1.2E-118 T 22-04-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HRM2_RS10425 1d866b16dce1aac22ec5709ce920e4cc 490 Gene3D G3DSA:1.10.1040.10 361 483 1.5E-15 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HRM2_RS10425 1d866b16dce1aac22ec5709ce920e4cc 490 SUPERFAMILY SSF48179 210 341 4.65E-39 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HRM2_RS10425 1d866b16dce1aac22ec5709ce920e4cc 490 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 210 342 6.4E-27 T 22-04-2016 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HRM2_RS10425 1d866b16dce1aac22ec5709ce920e4cc 490 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 359 484 1.7E-17 T 22-04-2016 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HRM2_RS10425 1d866b16dce1aac22ec5709ce920e4cc 490 SUPERFAMILY SSF48179 349 486 1.0E-40 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HRM2_RS15345 70c8d1df7a5e8afba8b3d9e9c9596cce 401 Gene3D G3DSA:3.40.190.10 120 257 2.7E-12 T 22-04-2016 HRM2_RS15345 70c8d1df7a5e8afba8b3d9e9c9596cce 401 SUPERFAMILY SSF53850 37 273 4.27E-37 T 22-04-2016 HRM2_RS15345 70c8d1df7a5e8afba8b3d9e9c9596cce 401 Pfam PF13379 NMT1-like family 35 276 3.1E-46 T 22-04-2016 HRM2_RS15345 70c8d1df7a5e8afba8b3d9e9c9596cce 401 PANTHER PTHR30024:SF16 1 278 8.2E-69 T 22-04-2016 HRM2_RS15345 70c8d1df7a5e8afba8b3d9e9c9596cce 401 PANTHER PTHR30024 1 278 8.2E-69 T 22-04-2016 HRM2_RS19835 da519c9c0b160aca7e3680fe7829065b 225 PANTHER PTHR11911 76 133 5.8E-28 T 22-04-2016 HRM2_RS19835 da519c9c0b160aca7e3680fe7829065b 225 PANTHER PTHR11911 1 58 5.8E-28 T 22-04-2016 HRM2_RS19835 da519c9c0b160aca7e3680fe7829065b 225 SUPERFAMILY SSF54631 1 132 6.43E-31 T 22-04-2016 HRM2_RS19835 da519c9c0b160aca7e3680fe7829065b 225 Gene3D G3DSA:3.10.580.10 2 132 2.1E-29 T 22-04-2016 HRM2_RS19835 da519c9c0b160aca7e3680fe7829065b 225 SMART SM00116 84 132 1.1E-6 T 22-04-2016 IPR000644 CBS domain HRM2_RS19835 da519c9c0b160aca7e3680fe7829065b 225 SMART SM00116 10 57 4.1E-8 T 22-04-2016 IPR000644 CBS domain HRM2_RS19835 da519c9c0b160aca7e3680fe7829065b 225 Pfam PF00571 CBS domain 5 55 8.7E-11 T 22-04-2016 IPR000644 CBS domain HRM2_RS19835 da519c9c0b160aca7e3680fe7829065b 225 Pfam PF00571 CBS domain 78 132 1.6E-13 T 22-04-2016 IPR000644 CBS domain HRM2_RS24895 06417199163bf8ecb522174f7d6359f8 254 Pfam PF12697 Alpha/beta hydrolase family 25 245 5.9E-20 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HRM2_RS24895 06417199163bf8ecb522174f7d6359f8 254 PANTHER PTHR10992 21 253 2.5E-37 T 22-04-2016 HRM2_RS24895 06417199163bf8ecb522174f7d6359f8 254 SUPERFAMILY SSF53474 3 252 2.3E-43 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS24895 06417199163bf8ecb522174f7d6359f8 254 Gene3D G3DSA:3.40.50.1820 18 251 2.0E-44 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS10615 b10eb1d17720b40d0203327d3d058b1d 265 Pfam PF01841 Transglutaminase-like superfamily 116 217 7.5E-20 T 22-04-2016 IPR002931 Transglutaminase-like HRM2_RS10615 b10eb1d17720b40d0203327d3d058b1d 265 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 17 75 2.0E-4 T 22-04-2016 IPR013589 Bacterial transglutaminase-like, N-terminal HRM2_RS10615 b10eb1d17720b40d0203327d3d058b1d 265 SUPERFAMILY SSF54001 48 245 1.96E-33 T 22-04-2016 HRM2_RS10615 b10eb1d17720b40d0203327d3d058b1d 265 PANTHER PTHR33490 5 255 1.1E-63 T 22-04-2016 HRM2_RS10615 b10eb1d17720b40d0203327d3d058b1d 265 SMART SM00460 159 219 2.0E-13 T 22-04-2016 IPR002931 Transglutaminase-like HRM2_RS10615 b10eb1d17720b40d0203327d3d058b1d 265 Gene3D G3DSA:3.90.260.10 166 225 5.4E-6 T 22-04-2016 IPR002931 Transglutaminase-like HRM2_RS10615 b10eb1d17720b40d0203327d3d058b1d 265 PANTHER PTHR33490:SF3 5 255 1.1E-63 T 22-04-2016 HRM2_RS10660 40a6364068fc59fbefe17dd916def704 619 Pfam PF00005 ABC transporter 30 192 7.6E-26 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS10660 40a6364068fc59fbefe17dd916def704 619 Pfam PF00005 ABC transporter 344 493 8.8E-30 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS10660 40a6364068fc59fbefe17dd916def704 619 SUPERFAMILY SSF52540 10 264 6.21E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10660 40a6364068fc59fbefe17dd916def704 619 Gene3D G3DSA:3.40.50.300 9 266 4.1E-70 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10660 40a6364068fc59fbefe17dd916def704 619 Gene3D G3DSA:3.40.50.300 315 567 4.3E-76 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10660 40a6364068fc59fbefe17dd916def704 619 PANTHER PTHR24220 287 311 1.7E-162 T 22-04-2016 HRM2_RS10660 40a6364068fc59fbefe17dd916def704 619 PANTHER PTHR24220 12 271 1.7E-162 T 22-04-2016 HRM2_RS10660 40a6364068fc59fbefe17dd916def704 619 PANTHER PTHR24220 343 452 1.7E-162 T 22-04-2016 HRM2_RS10660 40a6364068fc59fbefe17dd916def704 619 SMART SM00382 352 543 2.9E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS10660 40a6364068fc59fbefe17dd916def704 619 SMART SM00382 39 242 8.6E-16 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS10660 40a6364068fc59fbefe17dd916def704 619 PANTHER PTHR24220:SF442 343 452 1.7E-162 T 22-04-2016 HRM2_RS10660 40a6364068fc59fbefe17dd916def704 619 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 244 272 1.5E-5 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HRM2_RS10660 40a6364068fc59fbefe17dd916def704 619 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 545 588 2.6E-8 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HRM2_RS10660 40a6364068fc59fbefe17dd916def704 619 SUPERFAMILY SSF52540 331 565 3.77E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10660 40a6364068fc59fbefe17dd916def704 619 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 543 592 3.5E-11 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HRM2_RS10660 40a6364068fc59fbefe17dd916def704 619 ProSitePatterns PS00211 ABC transporters family signature. 466 480 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS10660 40a6364068fc59fbefe17dd916def704 619 PANTHER PTHR24220:SF442 287 311 1.7E-162 T 22-04-2016 HRM2_RS10660 40a6364068fc59fbefe17dd916def704 619 PANTHER PTHR24220:SF442 12 271 1.7E-162 T 22-04-2016 HRM2_RS00955 0fd0db89e9a7a42dd41456a73d8736ea 368 PANTHER PTHR22893 4 363 8.0E-135 T 22-04-2016 HRM2_RS00955 0fd0db89e9a7a42dd41456a73d8736ea 368 Gene3D G3DSA:3.20.20.70 4 360 1.6E-107 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS00955 0fd0db89e9a7a42dd41456a73d8736ea 368 SUPERFAMILY SSF51395 4 363 4.28E-100 T 22-04-2016 HRM2_RS00955 0fd0db89e9a7a42dd41456a73d8736ea 368 PANTHER PTHR22893:SF53 4 363 8.0E-135 T 22-04-2016 HRM2_RS00955 0fd0db89e9a7a42dd41456a73d8736ea 368 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 333 4.4E-64 T 22-04-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 HRM2_RS24245 4e0b8a12d07070ee11535c1a85bf85ae 561 Pfam PF01935 Domain of unknown function DUF87 139 414 2.6E-49 T 22-04-2016 IPR002789 Helicase HerA, central domain HRM2_RS24245 4e0b8a12d07070ee11535c1a85bf85ae 561 PANTHER PTHR30121:SF2 29 556 1.4E-76 T 22-04-2016 IPR008571 Helicase HerA HRM2_RS24245 4e0b8a12d07070ee11535c1a85bf85ae 561 PANTHER PTHR30121 29 556 1.4E-76 T 22-04-2016 HRM2_RS24245 4e0b8a12d07070ee11535c1a85bf85ae 561 SUPERFAMILY SSF52540 245 538 4.56E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24245 4e0b8a12d07070ee11535c1a85bf85ae 561 SUPERFAMILY SSF52540 112 209 4.56E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24245 4e0b8a12d07070ee11535c1a85bf85ae 561 Gene3D G3DSA:3.40.50.300 374 537 4.3E-32 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24245 4e0b8a12d07070ee11535c1a85bf85ae 561 Gene3D G3DSA:3.40.50.300 141 228 4.3E-32 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08280 1ff1e578f1739177f2221bb797a5cec9 678 TIGRFAM TIGR01702 CO_DH_cata: carbon-monoxide dehydrogenase, catalytic subunit 27 659 5.3E-182 T 22-04-2016 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.99.2|KEGG: 00680+1.2.99.2|KEGG: 00720+1.2.99.2|MetaCyc: PWY-5372|MetaCyc: PWY-6780 HRM2_RS08280 1ff1e578f1739177f2221bb797a5cec9 678 Gene3D G3DSA:1.20.1270.30 85 266 8.6E-72 T 22-04-2016 IPR016101 CO dehydrogenase, alpha-bundle GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.99.2|KEGG: 00680+1.2.99.2|KEGG: 00720+1.2.99.2|MetaCyc: PWY-5372|MetaCyc: PWY-6780 HRM2_RS08280 1ff1e578f1739177f2221bb797a5cec9 678 PIRSF PIRSF005023 10 660 3.7E-207 T 22-04-2016 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.99.2|KEGG: 00680+1.2.99.2|KEGG: 00720+1.2.99.2|MetaCyc: PWY-5372|MetaCyc: PWY-6780 HRM2_RS08280 1ff1e578f1739177f2221bb797a5cec9 678 Pfam PF03063 Prismane/CO dehydrogenase family 62 639 2.8E-156 T 22-04-2016 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS08280 1ff1e578f1739177f2221bb797a5cec9 678 Gene3D G3DSA:3.40.50.2030 437 660 1.2E-80 T 22-04-2016 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS08280 1ff1e578f1739177f2221bb797a5cec9 678 PANTHER PTHR30109 23 660 3.4E-188 T 22-04-2016 HRM2_RS08280 1ff1e578f1739177f2221bb797a5cec9 678 SUPERFAMILY SSF56821 14 664 1.57E-173 T 22-04-2016 IPR011254 Prismane-like GO:0003824|GO:0016491|GO:0055114 HRM2_RS08280 1ff1e578f1739177f2221bb797a5cec9 678 PANTHER PTHR30109:SF4 23 660 3.4E-188 T 22-04-2016 HRM2_RS08280 1ff1e578f1739177f2221bb797a5cec9 678 Gene3D G3DSA:3.40.50.2030 269 436 4.1E-63 T 22-04-2016 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HRM2_RS25625 bef0bcdc3b8abd2705260006585c6ca0 244 Pfam PF04986 Putative transposase 16 166 3.7E-36 T 22-04-2016 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 HRM2_RS15970 489bf1413cb672dafbfeef3a8e9ebde4 1487 Pfam PF01493 GXGXG motif 1237 1421 1.9E-73 T 22-04-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 HRM2_RS15970 489bf1413cb672dafbfeef3a8e9ebde4 1487 Gene3D G3DSA:3.60.20.10 13 431 9.5E-162 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal HRM2_RS15970 489bf1413cb672dafbfeef3a8e9ebde4 1487 Gene3D G3DSA:3.20.20.70 444 780 1.0E-94 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS15970 489bf1413cb672dafbfeef3a8e9ebde4 1487 Pfam PF04898 Glutamate synthase central domain 459 736 3.5E-100 T 22-04-2016 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 UniPathway: UPA00045 HRM2_RS15970 489bf1413cb672dafbfeef3a8e9ebde4 1487 Gene3D G3DSA:3.20.20.70 821 1188 4.2E-161 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS15970 489bf1413cb672dafbfeef3a8e9ebde4 1487 PANTHER PTHR11938 2 1477 0.0 T 22-04-2016 HRM2_RS15970 489bf1413cb672dafbfeef3a8e9ebde4 1487 Pfam PF01645 Conserved region in glutamate synthase 794 1157 2.7E-153 T 22-04-2016 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 HRM2_RS15970 489bf1413cb672dafbfeef3a8e9ebde4 1487 SUPERFAMILY SSF51395 447 1192 3.66E-245 T 22-04-2016 HRM2_RS15970 489bf1413cb672dafbfeef3a8e9ebde4 1487 Gene3D G3DSA:2.160.20.60 1214 1465 3.5E-86 T 22-04-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 HRM2_RS15970 489bf1413cb672dafbfeef3a8e9ebde4 1487 Pfam PF00310 Glutamine amidotransferases class-II 13 426 5.9E-170 T 22-04-2016 IPR017932 Glutamine amidotransferase type 2 domain HRM2_RS15970 489bf1413cb672dafbfeef3a8e9ebde4 1487 SUPERFAMILY SSF69336 1212 1465 1.7E-82 T 22-04-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 HRM2_RS15970 489bf1413cb672dafbfeef3a8e9ebde4 1487 SUPERFAMILY SSF56235 13 429 1.62E-143 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal HRM2_RS15970 489bf1413cb672dafbfeef3a8e9ebde4 1487 PANTHER PTHR11938:SF1 2 1477 0.0 T 22-04-2016 HRM2_RS12010 4fc8dd93cdf03f59aa1dbc8dc8476081 66 Gene3D G3DSA:2.40.50.140 1 65 6.3E-31 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS12010 4fc8dd93cdf03f59aa1dbc8dc8476081 66 SMART SM00357 3 66 4.0E-30 T 22-04-2016 IPR011129 Cold shock protein GO:0003676 HRM2_RS12010 4fc8dd93cdf03f59aa1dbc8dc8476081 66 SUPERFAMILY SSF50249 1 65 2.04E-24 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS12010 4fc8dd93cdf03f59aa1dbc8dc8476081 66 PANTHER PTHR11544 1 66 3.4E-36 T 22-04-2016 HRM2_RS12010 4fc8dd93cdf03f59aa1dbc8dc8476081 66 PRINTS PR00050 Cold shock protein signature 4 19 2.5E-18 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HRM2_RS12010 4fc8dd93cdf03f59aa1dbc8dc8476081 66 PRINTS PR00050 Cold shock protein signature 39 57 2.5E-18 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HRM2_RS12010 4fc8dd93cdf03f59aa1dbc8dc8476081 66 PRINTS PR00050 Cold shock protein signature 24 33 2.5E-18 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HRM2_RS12010 4fc8dd93cdf03f59aa1dbc8dc8476081 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.7E-29 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HRM2_RS12010 4fc8dd93cdf03f59aa1dbc8dc8476081 66 PIRSF PIRSF002599 1 66 3.5E-24 T 22-04-2016 IPR012156 Cold shock, CspA GO:0003676 HRM2_RS12010 4fc8dd93cdf03f59aa1dbc8dc8476081 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 22-04-2016 IPR019844 Cold-shock conserved site HRM2_RS15790 74f2ed84be336c44a94d8a1ff2dad5e3 339 SUPERFAMILY SSF47384 84 161 3.73E-15 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS15790 74f2ed84be336c44a94d8a1ff2dad5e3 339 SMART SM00387 206 320 3.5E-23 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS15790 74f2ed84be336c44a94d8a1ff2dad5e3 339 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 212 319 1.0E-15 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS15790 74f2ed84be336c44a94d8a1ff2dad5e3 339 SMART SM00388 95 161 9.4E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS15790 74f2ed84be336c44a94d8a1ff2dad5e3 339 Gene3D G3DSA:3.30.565.10 149 320 3.4E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS15790 74f2ed84be336c44a94d8a1ff2dad5e3 339 Gene3D G3DSA:1.10.287.130 90 148 9.0E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS15790 74f2ed84be336c44a94d8a1ff2dad5e3 339 PRINTS PR00344 Bacterial sensor protein C-terminal signature 244 258 1.7E-10 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS15790 74f2ed84be336c44a94d8a1ff2dad5e3 339 PRINTS PR00344 Bacterial sensor protein C-terminal signature 304 317 1.7E-10 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS15790 74f2ed84be336c44a94d8a1ff2dad5e3 339 PRINTS PR00344 Bacterial sensor protein C-terminal signature 262 272 1.7E-10 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS15790 74f2ed84be336c44a94d8a1ff2dad5e3 339 PRINTS PR00344 Bacterial sensor protein C-terminal signature 279 297 1.7E-10 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS15790 74f2ed84be336c44a94d8a1ff2dad5e3 339 PANTHER PTHR24423 91 315 2.5E-41 T 22-04-2016 HRM2_RS15790 74f2ed84be336c44a94d8a1ff2dad5e3 339 PANTHER PTHR24423 37 43 2.5E-41 T 22-04-2016 HRM2_RS15790 74f2ed84be336c44a94d8a1ff2dad5e3 339 SUPERFAMILY SSF55874 150 318 3.77E-30 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS15790 74f2ed84be336c44a94d8a1ff2dad5e3 339 Pfam PF00512 His Kinase A (phospho-acceptor) domain 98 160 1.0E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS10855 7ea78bd2fcf6e599c3496d793a6dc494 417 Gene3D G3DSA:3.65.10.10 219 416 1.6E-57 T 22-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 HRM2_RS10855 7ea78bd2fcf6e599c3496d793a6dc494 417 PANTHER PTHR21090 1 416 2.7E-194 T 22-04-2016 HRM2_RS10855 7ea78bd2fcf6e599c3496d793a6dc494 417 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 416 45.561 T 22-04-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS10855 7ea78bd2fcf6e599c3496d793a6dc494 417 Gene3D G3DSA:3.65.10.10 21 218 1.3E-63 T 22-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 HRM2_RS10855 7ea78bd2fcf6e599c3496d793a6dc494 417 SUPERFAMILY SSF55205 1 416 9.42E-138 T 22-04-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 HRM2_RS10855 7ea78bd2fcf6e599c3496d793a6dc494 417 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 405 8.6E-101 T 22-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 HRM2_RS10855 7ea78bd2fcf6e599c3496d793a6dc494 417 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 415 1.1E-172 T 22-04-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS10855 7ea78bd2fcf6e599c3496d793a6dc494 417 PANTHER PTHR21090:SF19 1 416 2.7E-194 T 22-04-2016 HRM2_RS16780 1b698c04cb2052e2166e1150019d7c44 305 SUPERFAMILY SSF103473 1 269 2.35E-20 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS16780 1b698c04cb2052e2166e1150019d7c44 305 Gene3D G3DSA:1.20.1250.20 14 187 4.8E-15 T 22-04-2016 HRM2_RS16780 1b698c04cb2052e2166e1150019d7c44 305 PANTHER PTHR23531 1 278 1.1E-12 T 22-04-2016 HRM2_RS16780 1b698c04cb2052e2166e1150019d7c44 305 Pfam PF07690 Major Facilitator Superfamily 17 268 1.9E-11 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS03900 d6e429a957b7be00f4fe449017a61233 278 PANTHER PTHR30151:SF8 12 120 3.4E-64 T 22-04-2016 HRM2_RS03900 d6e429a957b7be00f4fe449017a61233 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 267 1.3E-16 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS03900 d6e429a957b7be00f4fe449017a61233 278 PANTHER PTHR30151 12 120 3.4E-64 T 22-04-2016 HRM2_RS03900 d6e429a957b7be00f4fe449017a61233 278 Gene3D G3DSA:1.10.3720.10 58 267 9.0E-19 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS03900 d6e429a957b7be00f4fe449017a61233 278 PANTHER PTHR30151:SF8 144 278 3.4E-64 T 22-04-2016 HRM2_RS03900 d6e429a957b7be00f4fe449017a61233 278 PANTHER PTHR30151 144 278 3.4E-64 T 22-04-2016 HRM2_RS03900 d6e429a957b7be00f4fe449017a61233 278 SUPERFAMILY SSF161098 58 263 8.76E-27 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS04955 a884faa1d6db637883d11ad923052ea4 282 Gene3D G3DSA:1.10.1040.10 188 282 1.2E-37 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HRM2_RS04955 a884faa1d6db637883d11ad923052ea4 282 PIRSF PIRSF000105 1 282 3.1E-87 T 22-04-2016 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 HRM2_RS04955 a884faa1d6db637883d11ad923052ea4 282 PANTHER PTHR23309 1 282 3.3E-149 T 22-04-2016 HRM2_RS04955 a884faa1d6db637883d11ad923052ea4 282 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 183 6.1E-63 T 22-04-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 HRM2_RS04955 a884faa1d6db637883d11ad923052ea4 282 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 282 2.5E-36 T 22-04-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 HRM2_RS04955 a884faa1d6db637883d11ad923052ea4 282 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 183 208 - T 22-04-2016 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 HRM2_RS04955 a884faa1d6db637883d11ad923052ea4 282 Gene3D G3DSA:3.40.50.720 6 187 1.6E-60 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS04955 a884faa1d6db637883d11ad923052ea4 282 SUPERFAMILY SSF51735 2 185 2.7E-57 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS04955 a884faa1d6db637883d11ad923052ea4 282 SUPERFAMILY SSF48179 185 282 1.11E-35 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HRM2_RS05055 e13c95dd7c92602ca3b51e79c4f9911d 353 Pfam PF01544 CorA-like Mg2+ transporter protein 60 349 1.4E-70 T 22-04-2016 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 HRM2_RS05055 e13c95dd7c92602ca3b51e79c4f9911d 353 Gene3D G3DSA:3.30.460.20 4 163 2.6E-47 T 22-04-2016 HRM2_RS05055 e13c95dd7c92602ca3b51e79c4f9911d 353 Gene3D G3DSA:1.20.58.340 164 275 1.2E-36 T 22-04-2016 HRM2_RS05055 e13c95dd7c92602ca3b51e79c4f9911d 353 SUPERFAMILY SSF144083 288 350 1.83E-23 T 22-04-2016 HRM2_RS05055 e13c95dd7c92602ca3b51e79c4f9911d 353 PANTHER PTHR21535:SF33 21 353 1.6E-67 T 22-04-2016 HRM2_RS05055 e13c95dd7c92602ca3b51e79c4f9911d 353 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 56 353 5.7E-89 T 22-04-2016 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 HRM2_RS05055 e13c95dd7c92602ca3b51e79c4f9911d 353 SUPERFAMILY SSF143865 10 287 2.35E-80 T 22-04-2016 HRM2_RS05055 e13c95dd7c92602ca3b51e79c4f9911d 353 Gene3D G3DSA:1.20.58.340 277 353 5.2E-33 T 22-04-2016 HRM2_RS05055 e13c95dd7c92602ca3b51e79c4f9911d 353 PANTHER PTHR21535 21 353 1.6E-67 T 22-04-2016 HRM2_RS22390 dca20bad726cee42898444109677960c 888 SMART SM00490 624 706 6.8E-22 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS22390 dca20bad726cee42898444109677960c 888 PANTHER PTHR10799 293 773 2.9E-104 T 22-04-2016 HRM2_RS22390 dca20bad726cee42898444109677960c 888 PANTHER PTHR10799 803 823 2.9E-104 T 22-04-2016 HRM2_RS22390 dca20bad726cee42898444109677960c 888 Pfam PF00271 Helicase conserved C-terminal domain 600 706 1.9E-19 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS22390 dca20bad726cee42898444109677960c 888 SUPERFAMILY SSF52540 282 515 4.99E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22390 dca20bad726cee42898444109677960c 888 SMART SM00487 301 482 4.0E-24 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS22390 dca20bad726cee42898444109677960c 888 Pfam PF04434 SWIM zinc finger 57 87 2.3E-4 T 22-04-2016 IPR007527 Zinc finger, SWIM-type GO:0008270 HRM2_RS22390 dca20bad726cee42898444109677960c 888 SUPERFAMILY SSF52540 517 767 1.27E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22390 dca20bad726cee42898444109677960c 888 Pfam PF00176 SNF2 family N-terminal domain 321 544 2.0E-34 T 22-04-2016 IPR000330 SNF2-related, N-terminal domain GO:0005524 HRM2_RS22390 dca20bad726cee42898444109677960c 888 Gene3D G3DSA:3.40.50.300 592 731 4.8E-28 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22390 dca20bad726cee42898444109677960c 888 Gene3D G3DSA:3.40.50.300 299 469 1.3E-17 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06205 43d0ed21038db1a0e14fd5693820d1ee 946 Pfam PF01935 Domain of unknown function DUF87 663 723 7.1E-6 T 22-04-2016 IPR002789 Helicase HerA, central domain HRM2_RS06205 43d0ed21038db1a0e14fd5693820d1ee 946 SMART SM00382 667 877 0.16 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS06205 43d0ed21038db1a0e14fd5693820d1ee 946 SMART SM00382 57 335 3.3 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS06205 43d0ed21038db1a0e14fd5693820d1ee 946 PANTHER PTHR30121 768 916 3.6E-13 T 22-04-2016 HRM2_RS06205 43d0ed21038db1a0e14fd5693820d1ee 946 Gene3D G3DSA:3.40.50.300 643 923 8.1E-31 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06205 43d0ed21038db1a0e14fd5693820d1ee 946 Gene3D G3DSA:3.40.50.300 60 122 3.9E-4 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06205 43d0ed21038db1a0e14fd5693820d1ee 946 SUPERFAMILY SSF52540 639 918 6.99E-24 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23330 d6db24690de3b0286878f034763e4fdd 84 Pfam PF00550 Phosphopantetheine attachment site 12 71 1.3E-7 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain HRM2_RS23330 d6db24690de3b0286878f034763e4fdd 84 Gene3D G3DSA:1.10.1200.10 5 79 4.5E-12 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain HRM2_RS23330 d6db24690de3b0286878f034763e4fdd 84 SUPERFAMILY SSF47336 5 79 2.75E-11 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain HRM2_RS09005 4984b0ea240378714eefc3a3b7657db0 211 Pfam PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain 147 203 5.2E-11 T 22-04-2016 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|UniPathway: UPA00060 HRM2_RS09005 4984b0ea240378714eefc3a3b7657db0 211 SUPERFAMILY SSF63999 4 131 1.96E-35 T 22-04-2016 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356 HRM2_RS09005 4984b0ea240378714eefc3a3b7657db0 211 SMART SM00983 134 205 2.6E-13 T 22-04-2016 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|UniPathway: UPA00060 HRM2_RS09005 4984b0ea240378714eefc3a3b7657db0 211 Gene3D G3DSA:2.60.120.320 145 208 3.8E-8 T 22-04-2016 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|UniPathway: UPA00060 HRM2_RS09005 4984b0ea240378714eefc3a3b7657db0 211 PANTHER PTHR41299 4 211 2.9E-42 T 22-04-2016 HRM2_RS09005 4984b0ea240378714eefc3a3b7657db0 211 Gene3D G3DSA:3.40.50.10240 2 133 5.6E-34 T 22-04-2016 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356 HRM2_RS09005 4984b0ea240378714eefc3a3b7657db0 211 PANTHER PTHR41299:SF1 4 211 2.9E-42 T 22-04-2016 HRM2_RS09005 4984b0ea240378714eefc3a3b7657db0 211 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 23 120 1.6E-26 T 22-04-2016 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356 HRM2_RS09005 4984b0ea240378714eefc3a3b7657db0 211 SUPERFAMILY SSF63862 148 206 5.89E-8 T 22-04-2016 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|UniPathway: UPA00060 HRM2_RS09005 4984b0ea240378714eefc3a3b7657db0 211 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 5 206 1.5E-54 T 22-04-2016 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|UniPathway: UPA00060 HRM2_RS11490 24990dd1949b95b27ce23ffe0798f347 207 TIGRFAM TIGR00172 maf: septum formation protein Maf 9 191 4.6E-54 T 22-04-2016 IPR003697 Maf-like protein GO:0005737 HRM2_RS11490 24990dd1949b95b27ce23ffe0798f347 207 Pfam PF02545 Maf-like protein 11 191 4.1E-57 T 22-04-2016 IPR003697 Maf-like protein GO:0005737 HRM2_RS11490 24990dd1949b95b27ce23ffe0798f347 207 PIRSF PIRSF006305 4 198 5.5E-55 T 22-04-2016 IPR003697 Maf-like protein GO:0005737 HRM2_RS11490 24990dd1949b95b27ce23ffe0798f347 207 Hamap MF_00528 Septum formation protein Maf [maf]. 11 198 30.282 T 22-04-2016 IPR003697 Maf-like protein GO:0005737 HRM2_RS11490 24990dd1949b95b27ce23ffe0798f347 207 Gene3D G3DSA:3.90.950.10 10 195 6.3E-66 T 22-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like HRM2_RS11490 24990dd1949b95b27ce23ffe0798f347 207 SUPERFAMILY SSF52972 8 191 2.88E-62 T 22-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like HRM2_RS15975 e0ef9d3b29d913da1a3f39abace85f79 476 TIGRFAM TIGR01318 gltD_gamma_fam: glutamate synthase, small subunit 6 470 1.9E-231 T 22-04-2016 IPR006006 Glutamate synthase, NADH/NADPH, small subunit 2 GO:0006537|GO:0016639 HRM2_RS15975 e0ef9d3b29d913da1a3f39abace85f79 476 SUPERFAMILY SSF51971 145 400 3.47E-62 T 22-04-2016 HRM2_RS15975 e0ef9d3b29d913da1a3f39abace85f79 476 PRINTS PR00419 Adrenodoxin reductase family signature 148 170 4.3E-34 T 22-04-2016 HRM2_RS15975 e0ef9d3b29d913da1a3f39abace85f79 476 PRINTS PR00419 Adrenodoxin reductase family signature 289 303 4.3E-34 T 22-04-2016 HRM2_RS15975 e0ef9d3b29d913da1a3f39abace85f79 476 PRINTS PR00419 Adrenodoxin reductase family signature 323 336 4.3E-34 T 22-04-2016 HRM2_RS15975 e0ef9d3b29d913da1a3f39abace85f79 476 PRINTS PR00419 Adrenodoxin reductase family signature 213 223 4.3E-34 T 22-04-2016 HRM2_RS15975 e0ef9d3b29d913da1a3f39abace85f79 476 PRINTS PR00419 Adrenodoxin reductase family signature 171 184 4.3E-34 T 22-04-2016 HRM2_RS15975 e0ef9d3b29d913da1a3f39abace85f79 476 SUPERFAMILY SSF46548 6 157 5.07E-37 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS15975 e0ef9d3b29d913da1a3f39abace85f79 476 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 24 134 8.8E-37 T 22-04-2016 IPR028261 Dihydroprymidine dehydrogenase domain II HRM2_RS15975 e0ef9d3b29d913da1a3f39abace85f79 476 Gene3D G3DSA:3.40.50.720 150 236 6.1E-31 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS15975 e0ef9d3b29d913da1a3f39abace85f79 476 Gene3D G3DSA:3.40.50.720 400 474 6.1E-31 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS15975 e0ef9d3b29d913da1a3f39abace85f79 476 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 147 458 2.6E-21 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS15975 e0ef9d3b29d913da1a3f39abace85f79 476 Gene3D G3DSA:3.50.50.60 237 399 4.8E-47 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS15975 e0ef9d3b29d913da1a3f39abace85f79 476 Gene3D G3DSA:1.10.1060.10 5 149 2.2E-42 T 22-04-2016 HRM2_RS15975 e0ef9d3b29d913da1a3f39abace85f79 476 PANTHER PTHR11938:SF93 23 469 4.3E-249 T 22-04-2016 HRM2_RS15975 e0ef9d3b29d913da1a3f39abace85f79 476 SUPERFAMILY SSF51971 374 471 1.0E-8 T 22-04-2016 HRM2_RS15975 e0ef9d3b29d913da1a3f39abace85f79 476 SUPERFAMILY SSF51971 333 348 1.0E-8 T 22-04-2016 HRM2_RS15975 e0ef9d3b29d913da1a3f39abace85f79 476 PANTHER PTHR11938 23 469 4.3E-249 T 22-04-2016 HRM2_RS18775 d7bfda2c49429a87c64e119b1ed85e3e 414 Gene3D G3DSA:3.30.1540.10 245 322 4.4E-16 T 22-04-2016 HRM2_RS18775 d7bfda2c49429a87c64e119b1ed85e3e 414 SUPERFAMILY SSF89796 16 413 1.7E-102 T 22-04-2016 IPR023606 CoA-transferase family III domain HRM2_RS18775 d7bfda2c49429a87c64e119b1ed85e3e 414 PANTHER PTHR24023:SF593 18 30 1.9E-35 T 22-04-2016 HRM2_RS18775 d7bfda2c49429a87c64e119b1ed85e3e 414 PANTHER PTHR24023:SF593 57 400 1.9E-35 T 22-04-2016 HRM2_RS18775 d7bfda2c49429a87c64e119b1ed85e3e 414 Gene3D G3DSA:3.40.50.10540 15 232 4.3E-92 T 22-04-2016 IPR023606 CoA-transferase family III domain HRM2_RS18775 d7bfda2c49429a87c64e119b1ed85e3e 414 Gene3D G3DSA:3.40.50.10540 323 413 4.3E-92 T 22-04-2016 IPR023606 CoA-transferase family III domain HRM2_RS18775 d7bfda2c49429a87c64e119b1ed85e3e 414 PANTHER PTHR24023 18 30 1.9E-35 T 22-04-2016 HRM2_RS18775 d7bfda2c49429a87c64e119b1ed85e3e 414 PANTHER PTHR24023 57 400 1.9E-35 T 22-04-2016 HRM2_RS18775 d7bfda2c49429a87c64e119b1ed85e3e 414 Pfam PF02515 CoA-transferase family III 18 390 7.9E-91 T 22-04-2016 IPR003673 CoA-transferase family III GO:0003824 HRM2_RS15415 2bdece583e6cfeddadfb1ef87afd7c82 208 SMART SM00849 12 189 3.3E-44 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS15415 2bdece583e6cfeddadfb1ef87afd7c82 208 PANTHER PTHR11935:SF8 1 208 1.5E-65 T 22-04-2016 HRM2_RS15415 2bdece583e6cfeddadfb1ef87afd7c82 208 PANTHER PTHR11935 1 208 1.5E-65 T 22-04-2016 HRM2_RS15415 2bdece583e6cfeddadfb1ef87afd7c82 208 SUPERFAMILY SSF56281 1 205 1.62E-55 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS15415 2bdece583e6cfeddadfb1ef87afd7c82 208 Pfam PF00753 Metallo-beta-lactamase superfamily 9 189 1.3E-32 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS15415 2bdece583e6cfeddadfb1ef87afd7c82 208 Gene3D G3DSA:3.60.15.10 11 205 2.3E-59 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS23090 cae33379b3898607c15957ea17348505 263 SMART SM00382 38 238 6.6E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS23090 cae33379b3898607c15957ea17348505 263 PANTHER PTHR24220:SF358 15 263 6.8E-104 T 22-04-2016 HRM2_RS23090 cae33379b3898607c15957ea17348505 263 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 239 260 1.4E-5 T 22-04-2016 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal HRM2_RS23090 cae33379b3898607c15957ea17348505 263 SUPERFAMILY SSF52540 13 259 3.97E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23090 cae33379b3898607c15957ea17348505 263 Gene3D G3DSA:3.40.50.300 11 259 4.3E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23090 cae33379b3898607c15957ea17348505 263 Pfam PF00005 ABC transporter 30 189 3.8E-28 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS23090 cae33379b3898607c15957ea17348505 263 PANTHER PTHR24220 15 263 6.8E-104 T 22-04-2016 HRM2_RS04520 82236bb4b958504302f2c11ec83eef7a 179 SUPERFAMILY SSF53271 6 171 5.51E-39 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like HRM2_RS04520 82236bb4b958504302f2c11ec83eef7a 179 Gene3D G3DSA:3.40.50.2020 6 171 7.8E-45 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like HRM2_RS04520 82236bb4b958504302f2c11ec83eef7a 179 Pfam PF00156 Phosphoribosyl transferase domain 6 149 1.6E-18 T 22-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 HRM2_RS04520 82236bb4b958504302f2c11ec83eef7a 179 PANTHER PTHR11608 1 179 6.6E-82 T 22-04-2016 HRM2_RS04520 82236bb4b958504302f2c11ec83eef7a 179 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 4 177 34.077 T 22-04-2016 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 HRM2_RS17795 7183cb4f2141099f15b70d81ffc29e4e 122 PIRSF PIRSF002134 1 122 6.4E-44 T 22-04-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17795 7183cb4f2141099f15b70d81ffc29e4e 122 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 22-04-2016 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 HRM2_RS17795 7183cb4f2141099f15b70d81ffc29e4e 122 Gene3D G3DSA:4.10.910.10 73 122 2.5E-26 T 22-04-2016 IPR027437 30s ribosomal protein S13, C-terminal HRM2_RS17795 7183cb4f2141099f15b70d81ffc29e4e 122 Pfam PF00416 Ribosomal protein S13/S18 3 109 1.4E-30 T 22-04-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17795 7183cb4f2141099f15b70d81ffc29e4e 122 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 1.1E-54 T 22-04-2016 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17795 7183cb4f2141099f15b70d81ffc29e4e 122 PANTHER PTHR10871 2 122 3.8E-66 T 22-04-2016 HRM2_RS17795 7183cb4f2141099f15b70d81ffc29e4e 122 Gene3D G3DSA:1.10.8.50 2 71 1.8E-30 T 22-04-2016 HRM2_RS17795 7183cb4f2141099f15b70d81ffc29e4e 122 SUPERFAMILY SSF46946 2 115 2.49E-45 T 22-04-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 HRM2_RS17795 7183cb4f2141099f15b70d81ffc29e4e 122 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 27.685 T 22-04-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS13810 9c294da3ee163dc3f6e49bd78ff239dd 293 PANTHER PTHR30448 1 289 1.1E-125 T 22-04-2016 HRM2_RS13810 9c294da3ee163dc3f6e49bd78ff239dd 293 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 4 288 39.017 T 22-04-2016 IPR005337 RapZ-like family GO:0005524 HRM2_RS13810 9c294da3ee163dc3f6e49bd78ff239dd 293 PIRSF PIRSF005052 4 291 4.5E-100 T 22-04-2016 IPR005337 RapZ-like family GO:0005524 HRM2_RS13810 9c294da3ee163dc3f6e49bd78ff239dd 293 SUPERFAMILY SSF52540 6 157 4.65E-13 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13810 9c294da3ee163dc3f6e49bd78ff239dd 293 Pfam PF03668 P-loop ATPase protein family 6 288 5.4E-93 T 22-04-2016 IPR005337 RapZ-like family GO:0005524 HRM2_RS13810 9c294da3ee163dc3f6e49bd78ff239dd 293 Gene3D G3DSA:3.40.50.300 5 158 1.1E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13810 9c294da3ee163dc3f6e49bd78ff239dd 293 PANTHER PTHR30448:SF0 1 289 1.1E-125 T 22-04-2016 HRM2_RS20785 9295bc89b3d992fa14d52b120c280e30 224 PANTHER PTHR31088:SF7 2 215 6.6E-56 T 22-04-2016 HRM2_RS20785 9295bc89b3d992fa14d52b120c280e30 224 PANTHER PTHR31088 2 215 6.6E-56 T 22-04-2016 HRM2_RS20785 9295bc89b3d992fa14d52b120c280e30 224 Pfam PF04012 PspA/IM30 family 2 215 1.8E-39 T 22-04-2016 IPR007157 PspA/IM30 HRM2_RS23435 44a9cf9935411a6cc328946124e26cf3 278 Gene3D G3DSA:3.30.1600.10 127 183 2.6E-21 T 22-04-2016 IPR026591 Sirtuin family, catalytic core small domain HRM2_RS23435 44a9cf9935411a6cc328946124e26cf3 278 Gene3D G3DSA:3.30.1600.10 33 74 2.6E-21 T 22-04-2016 IPR026591 Sirtuin family, catalytic core small domain HRM2_RS23435 44a9cf9935411a6cc328946124e26cf3 278 PANTHER PTHR11085:SF17 7 269 1.4E-54 T 22-04-2016 HRM2_RS23435 44a9cf9935411a6cc328946124e26cf3 278 Pfam PF02146 Sir2 family 22 211 1.1E-32 T 22-04-2016 IPR003000 Sirtuin family GO:0070403 HRM2_RS23435 44a9cf9935411a6cc328946124e26cf3 278 Gene3D G3DSA:3.40.50.1220 9 32 1.6E-26 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HRM2_RS23435 44a9cf9935411a6cc328946124e26cf3 278 Gene3D G3DSA:3.40.50.1220 192 271 1.6E-26 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HRM2_RS23435 44a9cf9935411a6cc328946124e26cf3 278 Gene3D G3DSA:3.40.50.1220 86 126 1.6E-26 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HRM2_RS23435 44a9cf9935411a6cc328946124e26cf3 278 PANTHER PTHR11085 7 269 1.4E-54 T 22-04-2016 IPR003000 Sirtuin family GO:0070403 HRM2_RS23435 44a9cf9935411a6cc328946124e26cf3 278 SUPERFAMILY SSF52467 6 270 1.68E-63 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HRM2_RS01210 593f6ccd445bd2eaa026278b7f91f4a7 153 SUPERFAMILY SSF55874 42 122 2.62E-11 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS01210 593f6ccd445bd2eaa026278b7f91f4a7 153 Gene3D G3DSA:3.30.565.10 40 122 5.2E-10 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS01210 593f6ccd445bd2eaa026278b7f91f4a7 153 Pfam PF13581 Histidine kinase-like ATPase domain 18 140 3.1E-21 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS17735 bfc105a339bc009513e8fba823ae769e 470 PANTHER PTHR32328:SF0 4 470 6.4E-192 T 22-04-2016 HRM2_RS17735 bfc105a339bc009513e8fba823ae769e 470 Hamap MF_00423 L-seryl-tRNA(Sec) selenium transferase [selA]. 1 467 210.275 T 22-04-2016 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1|UniPathway: UPA00906 HRM2_RS17735 bfc105a339bc009513e8fba823ae769e 470 Gene3D G3DSA:3.40.640.10 133 317 8.8E-30 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS17735 bfc105a339bc009513e8fba823ae769e 470 Pfam PF03841 L-seryl-tRNA selenium transferase 85 449 2.2E-157 T 22-04-2016 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1|UniPathway: UPA00906 HRM2_RS17735 bfc105a339bc009513e8fba823ae769e 470 TIGRFAM TIGR00474 selA: L-seryl-tRNA(Sec) selenium transferase 10 461 3.9E-180 T 22-04-2016 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1|UniPathway: UPA00906 HRM2_RS17735 bfc105a339bc009513e8fba823ae769e 470 PANTHER PTHR32328 4 470 6.4E-192 T 22-04-2016 HRM2_RS17735 bfc105a339bc009513e8fba823ae769e 470 SUPERFAMILY SSF53383 78 462 7.74E-43 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS17735 bfc105a339bc009513e8fba823ae769e 470 Pfam PF12390 Selenocysteine synthase N terminal 10 49 1.1E-6 T 22-04-2016 IPR025862 L-seryl-tRNA selenium transferase N-terminal domain KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1|UniPathway: UPA00906 HRM2_RS04845 7c89b5bb73506f04212b33465fcbf502 81 TIGRFAM TIGR03798 ocin_TIGR03798: nif11-like leader peptide domain 1 53 7.4E-9 T 22-04-2016 IPR022516 Nif11-like leader peptide HRM2_RS04845 7c89b5bb73506f04212b33465fcbf502 81 Pfam PF07862 Nitrogen fixation protein of unknown function 1 48 1.2E-10 T 22-04-2016 IPR012903 Uncharacterised protein family, nitrogen fixation HRM2_RS00845 e90dc0ab8cd084068a385383db281ae8 425 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 183 422 1.2E-63 T 22-04-2016 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 HRM2_RS00845 e90dc0ab8cd084068a385383db281ae8 425 Gene3D G3DSA:1.10.3720.10 182 424 3.9E-47 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS00845 e90dc0ab8cd084068a385383db281ae8 425 Gene3D G3DSA:1.10.3720.10 35 60 3.9E-47 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS00845 e90dc0ab8cd084068a385383db281ae8 425 SUPERFAMILY SSF161098 201 411 7.19E-36 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS00845 e90dc0ab8cd084068a385383db281ae8 425 PANTHER PTHR30425:SF2 1 58 8.7E-91 T 22-04-2016 HRM2_RS00845 e90dc0ab8cd084068a385383db281ae8 425 PANTHER PTHR30425:SF2 173 424 8.7E-91 T 22-04-2016 HRM2_RS00845 e90dc0ab8cd084068a385383db281ae8 425 PANTHER PTHR30425 1 58 8.7E-91 T 22-04-2016 HRM2_RS00845 e90dc0ab8cd084068a385383db281ae8 425 PANTHER PTHR30425 173 424 8.7E-91 T 22-04-2016 HRM2_RS00845 e90dc0ab8cd084068a385383db281ae8 425 Pfam PF11812 Domain of unknown function (DUF3333) 16 159 8.8E-53 T 22-04-2016 IPR024573 Domain of unknown function DUF3333 HRM2_RS00845 e90dc0ab8cd084068a385383db281ae8 425 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 223 424 8.7E-20 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS04225 f8a47ce73a8345a2b69c800c4d4b70bb 651 Pfam PF06874 Firmicute fructose-1,6-bisphosphatase 10 647 2.6E-269 T 22-04-2016 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 HRM2_RS04225 f8a47ce73a8345a2b69c800c4d4b70bb 651 Hamap MF_01854 Fructose-1,6-bisphosphatase class 3 [fbp]. 7 649 34.476 T 22-04-2016 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 HRM2_RS04225 f8a47ce73a8345a2b69c800c4d4b70bb 651 Gene3D G3DSA:3.60.21.10 297 298 7.3E-6 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS04225 f8a47ce73a8345a2b69c800c4d4b70bb 651 Gene3D G3DSA:3.60.21.10 518 566 7.3E-6 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS04225 f8a47ce73a8345a2b69c800c4d4b70bb 651 Gene3D G3DSA:3.60.21.10 388 425 7.3E-6 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS04225 f8a47ce73a8345a2b69c800c4d4b70bb 651 Gene3D G3DSA:3.60.21.10 191 236 7.3E-6 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS04225 f8a47ce73a8345a2b69c800c4d4b70bb 651 Gene3D G3DSA:3.60.21.10 460 476 7.3E-6 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS04225 f8a47ce73a8345a2b69c800c4d4b70bb 651 PIRSF PIRSF000906 4 650 6.0E-254 T 22-04-2016 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 HRM2_RS04225 f8a47ce73a8345a2b69c800c4d4b70bb 651 SUPERFAMILY SSF56300 188 243 3.26E-6 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS01790 9ddfeeb86eace6cf7317612719073b84 540 Gene3D G3DSA:2.160.20.10 15 96 7.9E-28 T 22-04-2016 IPR012334 Pectin lyase fold HRM2_RS01790 9ddfeeb86eace6cf7317612719073b84 540 Gene3D G3DSA:2.160.20.10 209 368 7.9E-28 T 22-04-2016 IPR012334 Pectin lyase fold HRM2_RS01790 9ddfeeb86eace6cf7317612719073b84 540 SUPERFAMILY SSF51126 17 118 8.28E-22 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor HRM2_RS01790 9ddfeeb86eace6cf7317612719073b84 540 SUPERFAMILY SSF51126 248 456 8.28E-22 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor HRM2_RS01790 9ddfeeb86eace6cf7317612719073b84 540 Pfam PF12708 Pectate lyase superfamily protein 21 91 3.1E-11 T 22-04-2016 IPR024535 Pectate lyase superfamily protein HRM2_RS20190 5dbbe9563db3f98c8068ea524472bbdd 363 Pfam PF13847 Methyltransferase domain 173 337 4.4E-22 T 22-04-2016 IPR025714 Methyltransferase domain HRM2_RS20190 5dbbe9563db3f98c8068ea524472bbdd 363 Gene3D G3DSA:3.40.50.150 171 353 8.5E-30 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS20190 5dbbe9563db3f98c8068ea524472bbdd 363 PANTHER PTHR10108 40 345 1.8E-32 T 22-04-2016 HRM2_RS20190 5dbbe9563db3f98c8068ea524472bbdd 363 SUPERFAMILY SSF53335 171 356 7.15E-32 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS20190 5dbbe9563db3f98c8068ea524472bbdd 363 SUPERFAMILY SSF46785 9 88 2.45E-7 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS20190 5dbbe9563db3f98c8068ea524472bbdd 363 PANTHER PTHR10108:SF17 40 345 1.8E-32 T 22-04-2016 HRM2_RS17675 eac8787362d9bfeaebd411ab48b35ea7 789 Pfam PF07698 7TM receptor with intracellular HD hydrolase 311 509 1.5E-31 T 22-04-2016 IPR011621 Metal-dependent phosphohydrolase, 7TM intracellular domain HRM2_RS17675 eac8787362d9bfeaebd411ab48b35ea7 789 Pfam PF01966 HD domain 534 677 5.5E-17 T 22-04-2016 IPR006674 HD domain HRM2_RS17675 eac8787362d9bfeaebd411ab48b35ea7 789 Pfam PF07697 7TM-HD extracellular 49 297 1.9E-36 T 22-04-2016 IPR011624 Metal-dependent phosphohydrolase, 7TM extracellular domain HRM2_RS17675 eac8787362d9bfeaebd411ab48b35ea7 789 Gene3D G3DSA:1.10.3210.10 531 704 3.1E-25 T 22-04-2016 IPR006674 HD domain HRM2_RS17675 eac8787362d9bfeaebd411ab48b35ea7 789 PANTHER PTHR36442 13 753 4.4E-179 T 22-04-2016 HRM2_RS17675 eac8787362d9bfeaebd411ab48b35ea7 789 SUPERFAMILY SSF109604 533 695 2.1E-14 T 22-04-2016 HRM2_RS17675 eac8787362d9bfeaebd411ab48b35ea7 789 TIGRFAM TIGR00277 HDIG: HDIG domain 531 629 2.1E-19 T 22-04-2016 IPR006675 HDIG domain HRM2_RS17675 eac8787362d9bfeaebd411ab48b35ea7 789 SMART SM00471 530 687 4.4E-9 T 22-04-2016 IPR003607 HD/PDEase domain HRM2_RS11530 05122e86341424e9411b390ad1a67043 251 PANTHER PTHR34857:SF2 1 251 7.6E-49 T 22-04-2016 HRM2_RS11530 05122e86341424e9411b390ad1a67043 251 Pfam PF02361 Cobalt transport protein 11 215 2.0E-31 T 22-04-2016 IPR003339 ABC/ECF transporter, transmembrane component HRM2_RS11530 05122e86341424e9411b390ad1a67043 251 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 16 211 1.5E-40 T 22-04-2016 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 HRM2_RS11530 05122e86341424e9411b390ad1a67043 251 PANTHER PTHR34857 1 251 7.6E-49 T 22-04-2016 HRM2_RS21335 9f28e3c9ade1a60004da08ce62de6b3a 190 Pfam PF13689 Domain of unknown function (DUF4154) 40 184 1.1E-44 T 22-04-2016 IPR025293 Protein of unknown function DUF4154 HRM2_RS12630 b80e0199b96ec77e917c96356f4a8c3f 463 Pfam PF13546 DDE superfamily endonuclease 70 255 1.3E-16 T 22-04-2016 HRM2_RS12630 b80e0199b96ec77e917c96356f4a8c3f 463 Gene3D G3DSA:3.90.350.10 314 351 1.1E-4 T 22-04-2016 IPR014736 Transposase, Tn5-like, core HRM2_RS12630 b80e0199b96ec77e917c96356f4a8c3f 463 SUPERFAMILY SSF53098 78 443 1.52E-39 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS25345 0e84bfdcc91bae808b641a2cc980ca7f 117 SUPERFAMILY SSF54292 23 103 2.23E-18 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 HRM2_RS25345 0e84bfdcc91bae808b641a2cc980ca7f 117 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 21 100 7.8E-27 T 22-04-2016 HRM2_RS25345 0e84bfdcc91bae808b641a2cc980ca7f 117 Gene3D G3DSA:3.10.20.30 23 107 8.2E-8 T 22-04-2016 IPR012675 Beta-grasp domain HRM2_RS18970 f47e0a21eadb682262edd32229baa7b0 326 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 201 282 4.6E-31 T 22-04-2016 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal HRM2_RS18970 f47e0a21eadb682262edd32229baa7b0 326 SUPERFAMILY SSF52467 200 319 1.36E-41 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HRM2_RS18970 f47e0a21eadb682262edd32229baa7b0 326 SMART SM00893 5 192 5.6E-30 T 22-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 HRM2_RS18970 f47e0a21eadb682262edd32229baa7b0 326 Gene3D G3DSA:3.40.50.620 3 187 2.2E-45 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS18970 f47e0a21eadb682262edd32229baa7b0 326 PIRSF PIRSF000089 1 324 1.0E-95 T 22-04-2016 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 HRM2_RS18970 f47e0a21eadb682262edd32229baa7b0 326 PANTHER PTHR10909:SF299 118 320 1.8E-45 T 22-04-2016 HRM2_RS18970 f47e0a21eadb682262edd32229baa7b0 326 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 263 289 - T 22-04-2016 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site HRM2_RS18970 f47e0a21eadb682262edd32229baa7b0 326 PANTHER PTHR10909 118 320 1.8E-45 T 22-04-2016 HRM2_RS18970 f47e0a21eadb682262edd32229baa7b0 326 Gene3D G3DSA:3.40.50.1220 194 320 4.2E-50 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HRM2_RS18970 f47e0a21eadb682262edd32229baa7b0 326 SUPERFAMILY SSF52402 3 191 1.05E-39 T 22-04-2016 HRM2_RS18970 f47e0a21eadb682262edd32229baa7b0 326 Pfam PF01012 Electron transfer flavoprotein domain 5 173 5.2E-38 T 22-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 HRM2_RS05835 f64269459624e888d7de9aaa6be23c50 333 Pfam PF01925 Sulfite exporter TauE/SafE 39 275 1.3E-16 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 HRM2_RS21765 a6dadbf182ecc14086d7cef893e34e9c 313 Gene3D G3DSA:1.10.3720.10 91 309 2.8E-18 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS21765 a6dadbf182ecc14086d7cef893e34e9c 313 PANTHER PTHR30465:SF21 1 313 7.6E-111 T 22-04-2016 HRM2_RS21765 a6dadbf182ecc14086d7cef893e34e9c 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 313 1.2E-38 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS21765 a6dadbf182ecc14086d7cef893e34e9c 313 PANTHER PTHR30465 1 313 7.6E-111 T 22-04-2016 HRM2_RS21765 a6dadbf182ecc14086d7cef893e34e9c 313 SUPERFAMILY SSF161098 91 295 1.11E-18 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS00920 43d756685fa9ab9c175c48e0b2d55659 345 Pfam PF02666 Phosphatidylserine decarboxylase 106 318 3.3E-40 T 22-04-2016 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|UniPathway: UPA00558 HRM2_RS00920 43d756685fa9ab9c175c48e0b2d55659 345 PANTHER PTHR10067 118 312 5.5E-22 T 22-04-2016 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|UniPathway: UPA00558 HRM2_RS00920 43d756685fa9ab9c175c48e0b2d55659 345 PANTHER PTHR10067:SF2 118 312 5.5E-22 T 22-04-2016 HRM2_RS15070 0d4bd26563e4c2ff369c5e1517951fd2 164 Gene3D G3DSA:3.30.420.10 6 162 3.3E-40 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS15070 0d4bd26563e4c2ff369c5e1517951fd2 164 SUPERFAMILY SSF53098 6 160 2.81E-28 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS15070 0d4bd26563e4c2ff369c5e1517951fd2 164 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 7 154 3.2E-32 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 HRM2_RS15070 0d4bd26563e4c2ff369c5e1517951fd2 164 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 65 81 7.7E-19 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 HRM2_RS15070 0d4bd26563e4c2ff369c5e1517951fd2 164 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 8 21 7.7E-19 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 HRM2_RS15070 0d4bd26563e4c2ff369c5e1517951fd2 164 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 112 131 7.7E-19 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 HRM2_RS15070 0d4bd26563e4c2ff369c5e1517951fd2 164 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 144 156 7.7E-19 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 HRM2_RS15070 0d4bd26563e4c2ff369c5e1517951fd2 164 PANTHER PTHR30194 1 161 2.1E-40 T 22-04-2016 HRM2_RS15070 0d4bd26563e4c2ff369c5e1517951fd2 164 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 5 159 30.338 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 HRM2_RS16455 40c55577d61b75f3cb663b09fb87f889 565 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 295 315 - T 22-04-2016 IPR020612 Methylthiotransferase, conserved site GO:0051539 HRM2_RS16455 40c55577d61b75f3cb663b09fb87f889 565 TIGRFAM TIGR03904 SAM_YgiQ: uncharacterized radical SAM protein YgiQ 2 558 5.3E-244 T 22-04-2016 IPR022946 Uncharacterised protein family UPF0313 HRM2_RS16455 40c55577d61b75f3cb663b09fb87f889 565 Pfam PF08497 Radical SAM N-terminal 2 294 2.1E-121 T 22-04-2016 IPR013704 Uncharacterised protein family UPF0313, N-terminal HRM2_RS16455 40c55577d61b75f3cb663b09fb87f889 565 SMART SM00729 291 545 9.2E-9 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS16455 40c55577d61b75f3cb663b09fb87f889 565 Pfam PF04055 Radical SAM superfamily 296 503 2.3E-13 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS16455 40c55577d61b75f3cb663b09fb87f889 565 SUPERFAMILY SSF102114 387 528 9.55E-12 T 22-04-2016 HRM2_RS16455 40c55577d61b75f3cb663b09fb87f889 565 SUPERFAMILY SSF102114 291 357 9.55E-12 T 22-04-2016 HRM2_RS16455 40c55577d61b75f3cb663b09fb87f889 565 Gene3D G3DSA:3.80.30.20 290 530 2.7E-37 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe HRM2_RS16455 40c55577d61b75f3cb663b09fb87f889 565 PANTHER PTHR32331 1 564 3.6E-297 T 22-04-2016 HRM2_RS08530 3f130524925ae092befa983c5a9c0606 269 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 227 253 - T 22-04-2016 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00557 HRM2_RS08530 3f130524925ae092befa983c5a9c0606 269 PANTHER PTHR13773 1 265 1.6E-60 T 22-04-2016 HRM2_RS08530 3f130524925ae092befa983c5a9c0606 269 Pfam PF01148 Cytidylyltransferase family 4 267 7.6E-65 T 22-04-2016 HRM2_RS01530 7032c4504a8babae18d22d02a654e8cb 241 TIGRFAM TIGR00035 asp_race: aspartate racemase 6 233 1.7E-45 T 22-04-2016 IPR004380 Aspartate racemase GO:0006520|GO:0016855 HRM2_RS01530 7032c4504a8babae18d22d02a654e8cb 241 Pfam PF01177 Asp/Glu/Hydantoin racemase 12 227 8.1E-49 T 22-04-2016 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS01530 7032c4504a8babae18d22d02a654e8cb 241 Gene3D G3DSA:3.40.50.1860 7 121 1.7E-35 T 22-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS01530 7032c4504a8babae18d22d02a654e8cb 241 Gene3D G3DSA:3.40.50.1860 122 209 2.6E-17 T 22-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS01530 7032c4504a8babae18d22d02a654e8cb 241 SUPERFAMILY SSF53681 125 231 1.96E-15 T 22-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS01530 7032c4504a8babae18d22d02a654e8cb 241 PANTHER PTHR21198:SF6 1 174 1.3E-32 T 22-04-2016 HRM2_RS01530 7032c4504a8babae18d22d02a654e8cb 241 PANTHER PTHR21198 1 174 1.3E-32 T 22-04-2016 HRM2_RS01530 7032c4504a8babae18d22d02a654e8cb 241 SUPERFAMILY SSF53681 7 118 2.42E-29 T 22-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS00935 00c70d0d3847456046f408baea570268 177 PANTHER PTHR33823 6 153 7.8E-21 T 22-04-2016 HRM2_RS00935 00c70d0d3847456046f408baea570268 177 SUPERFAMILY SSF57716 95 129 2.42E-5 T 22-04-2016 HRM2_RS00935 00c70d0d3847456046f408baea570268 177 SUPERFAMILY SSF109635 5 94 3.92E-15 T 22-04-2016 HRM2_RS07280 6d15c739ba5dd9e98e6c7d9d5d2e30cc 307 Pfam PF01040 UbiA prenyltransferase family 30 287 3.0E-31 T 22-04-2016 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 HRM2_RS07280 6d15c739ba5dd9e98e6c7d9d5d2e30cc 307 PANTHER PTHR11048 96 307 9.6E-14 T 22-04-2016 HRM2_RS12540 b0dc67c1551207b0d778a525e2e913ca 173 PANTHER PTHR36449 1 173 3.8E-43 T 22-04-2016 HRM2_RS12540 b0dc67c1551207b0d778a525e2e913ca 173 SUPERFAMILY SSF55729 20 152 1.8E-13 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS12540 b0dc67c1551207b0d778a525e2e913ca 173 Pfam PF13673 Acetyltransferase (GNAT) domain 93 154 2.4E-9 T 22-04-2016 IPR000182 GNAT domain GO:0008080 HRM2_RS12540 b0dc67c1551207b0d778a525e2e913ca 173 Gene3D G3DSA:3.40.630.30 39 153 4.0E-13 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS01010 e8936ff29409ee029a70256e1c505bc7 666 Gene3D G3DSA:3.60.40.10 582 663 9.7E-5 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 HRM2_RS01010 e8936ff29409ee029a70256e1c505bc7 666 Gene3D G3DSA:3.60.40.10 499 543 9.7E-5 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 HRM2_RS01010 e8936ff29409ee029a70256e1c505bc7 666 Pfam PF08269 Cache domain 30 318 1.8E-19 T 22-04-2016 IPR004010 Double Cache domain 2 HRM2_RS01010 e8936ff29409ee029a70256e1c505bc7 666 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 474 664 7.4E-49 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 HRM2_RS01010 e8936ff29409ee029a70256e1c505bc7 666 SUPERFAMILY SSF81606 460 665 1.31E-6 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 HRM2_RS01010 e8936ff29409ee029a70256e1c505bc7 666 PANTHER PTHR21021 40 45 7.5E-62 T 22-04-2016 HRM2_RS01010 e8936ff29409ee029a70256e1c505bc7 666 PANTHER PTHR21021 422 666 7.5E-62 T 22-04-2016 HRM2_RS01010 e8936ff29409ee029a70256e1c505bc7 666 Gene3D G3DSA:3.30.450.20 212 325 5.7E-7 T 22-04-2016 HRM2_RS01010 e8936ff29409ee029a70256e1c505bc7 666 SMART SM00331 447 664 2.3E-45 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 HRM2_RS01010 e8936ff29409ee029a70256e1c505bc7 666 SUPERFAMILY SSF158472 350 408 3.14E-5 T 22-04-2016 HRM2_RS01010 e8936ff29409ee029a70256e1c505bc7 666 Pfam PF00672 HAMP domain 331 406 7.3E-11 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS01010 e8936ff29409ee029a70256e1c505bc7 666 PANTHER PTHR21021:SF19 40 45 7.5E-62 T 22-04-2016 HRM2_RS01010 e8936ff29409ee029a70256e1c505bc7 666 PANTHER PTHR21021:SF19 422 666 7.5E-62 T 22-04-2016 HRM2_RS03370 5ed90403bc79de26c54d9148f0e3a139 210 PANTHER PTHR30586:SF1 2 198 4.9E-100 T 22-04-2016 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 HRM2_RS03370 5ed90403bc79de26c54d9148f0e3a139 210 TIGRFAM TIGR01939 nqrD: NADH:ubiquinone oxidoreductase, Na(+)-translocating, D subunit 6 201 2.1E-87 T 22-04-2016 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 HRM2_RS03370 5ed90403bc79de26c54d9148f0e3a139 210 Hamap MF_00428 Na(+)-translocating NADH-quinone reductase subunit D [nqrD]. 3 208 32.328 T 22-04-2016 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 HRM2_RS03370 5ed90403bc79de26c54d9148f0e3a139 210 Pfam PF02508 Rnf-Nqr subunit, membrane protein 10 195 2.4E-61 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 HRM2_RS03370 5ed90403bc79de26c54d9148f0e3a139 210 PIRSF PIRSF006102 4 210 2.5E-66 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 HRM2_RS03370 5ed90403bc79de26c54d9148f0e3a139 210 PANTHER PTHR30586 2 198 4.9E-100 T 22-04-2016 HRM2_RS13920 e8c6d76e434b3bfdf8f686bbeb499f5f 689 Gene3D G3DSA:1.10.3210.10 396 521 2.5E-4 T 22-04-2016 IPR006674 HD domain HRM2_RS13920 e8c6d76e434b3bfdf8f686bbeb499f5f 689 Pfam PF05746 DALR anticodon binding domain 582 683 1.8E-6 T 22-04-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 HRM2_RS13920 e8c6d76e434b3bfdf8f686bbeb499f5f 689 PANTHER PTHR30075 1 689 2.1E-271 T 22-04-2016 HRM2_RS13920 e8c6d76e434b3bfdf8f686bbeb499f5f 689 PANTHER PTHR30075:SF2 1 689 2.1E-271 T 22-04-2016 HRM2_RS13920 e8c6d76e434b3bfdf8f686bbeb499f5f 689 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 2 689 2.2E-199 T 22-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HRM2_RS13920 e8c6d76e434b3bfdf8f686bbeb499f5f 689 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 1 689 23.667 T 22-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HRM2_RS13920 e8c6d76e434b3bfdf8f686bbeb499f5f 689 SUPERFAMILY SSF109604 329 477 8.79E-13 T 22-04-2016 HRM2_RS13920 e8c6d76e434b3bfdf8f686bbeb499f5f 689 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 4 551 3.1E-186 T 22-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HRM2_RS13920 e8c6d76e434b3bfdf8f686bbeb499f5f 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 394 413 1.6E-31 T 22-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HRM2_RS13920 e8c6d76e434b3bfdf8f686bbeb499f5f 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 5 18 1.6E-31 T 22-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HRM2_RS13920 e8c6d76e434b3bfdf8f686bbeb499f5f 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 243 258 1.6E-31 T 22-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HRM2_RS13920 e8c6d76e434b3bfdf8f686bbeb499f5f 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 48 60 1.6E-31 T 22-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HRM2_RS13920 e8c6d76e434b3bfdf8f686bbeb499f5f 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 315 331 1.6E-31 T 22-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HRM2_RS18115 45538f50ef5ae343c6bc01c9c2b34745 333 TIGRFAM TIGR03589 PseB: UDP-N-acetylglucosamine 4,6-dehydratase (inverting) 1 326 2.5E-167 T 22-04-2016 IPR020025 UDP-N-acetylglucosamine 4,6-dehydratase (inverting) KEGG: 00010+4.2.1.11|KEGG: 00520+4.2.1.115|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6143|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|MetaCyc: PWY-7330|MetaCyc: PWY-7331|MetaCyc: PWY-7332|MetaCyc: PWY-7719 HRM2_RS18115 45538f50ef5ae343c6bc01c9c2b34745 333 Gene3D G3DSA:3.40.50.720 6 223 2.6E-43 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS18115 45538f50ef5ae343c6bc01c9c2b34745 333 PANTHER PTHR10366:SF360 6 263 1.6E-118 T 22-04-2016 HRM2_RS18115 45538f50ef5ae343c6bc01c9c2b34745 333 SUPERFAMILY SSF51735 1 270 3.08E-48 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS18115 45538f50ef5ae343c6bc01c9c2b34745 333 Pfam PF02719 Polysaccharide biosynthesis protein 7 279 4.7E-103 T 22-04-2016 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain HRM2_RS18115 45538f50ef5ae343c6bc01c9c2b34745 333 PANTHER PTHR10366 6 263 1.6E-118 T 22-04-2016 HRM2_RS07525 9c0dda2609d6c252de1571276f791d26 209 PANTHER PTHR39425:SF1 30 195 1.2E-35 T 22-04-2016 HRM2_RS07525 9c0dda2609d6c252de1571276f791d26 209 Gene3D G3DSA:3.90.10.10 62 208 1.3E-15 T 22-04-2016 HRM2_RS07525 9c0dda2609d6c252de1571276f791d26 209 PANTHER PTHR39425 30 195 1.2E-35 T 22-04-2016 HRM2_RS07525 9c0dda2609d6c252de1571276f791d26 209 SUPERFAMILY SSF48695 65 201 1.44E-24 T 22-04-2016 IPR011031 Multihaem cytochrome HRM2_RS18205 65e792a3137f993920b4b4b44dd0415e 141 Gene3D G3DSA:1.20.120.340 5 119 4.1E-24 T 22-04-2016 IPR003713 Flagellar protein FliS GO:0044780 HRM2_RS18205 65e792a3137f993920b4b4b44dd0415e 141 Pfam PF02561 Flagellar protein FliS 7 119 2.5E-26 T 22-04-2016 IPR003713 Flagellar protein FliS GO:0044780 HRM2_RS18205 65e792a3137f993920b4b4b44dd0415e 141 PANTHER PTHR34773 1 119 6.1E-13 T 22-04-2016 HRM2_RS18205 65e792a3137f993920b4b4b44dd0415e 141 SUPERFAMILY SSF101116 6 120 2.09E-21 T 22-04-2016 IPR003713 Flagellar protein FliS GO:0044780 HRM2_RS18205 65e792a3137f993920b4b4b44dd0415e 141 TIGRFAM TIGR00208 fliS: flagellar protein FliS 1 120 4.2E-15 T 22-04-2016 IPR003713 Flagellar protein FliS GO:0044780 HRM2_RS01540 bccb4a3e76e7d0aa32a5c5b6b78d5b43 399 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 45 390 3.5E-59 T 22-04-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase HRM2_RS01540 bccb4a3e76e7d0aa32a5c5b6b78d5b43 399 PANTHER PTHR30244:SF18 49 397 9.6E-71 T 22-04-2016 HRM2_RS01540 bccb4a3e76e7d0aa32a5c5b6b78d5b43 399 SUPERFAMILY SSF53383 14 395 5.24E-72 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS01540 bccb4a3e76e7d0aa32a5c5b6b78d5b43 399 PANTHER PTHR30244 49 397 9.6E-71 T 22-04-2016 HRM2_RS01540 bccb4a3e76e7d0aa32a5c5b6b78d5b43 399 Gene3D G3DSA:3.40.640.10 12 263 2.0E-56 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS14500 a7a255ef34978a06f12dd59735e05416 394 Pfam PF01458 Uncharacterized protein family (UPF0051) 145 366 2.0E-50 T 22-04-2016 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 HRM2_RS14500 a7a255ef34978a06f12dd59735e05416 394 PANTHER PTHR30508 30 388 1.9E-125 T 22-04-2016 HRM2_RS14500 a7a255ef34978a06f12dd59735e05416 394 SUPERFAMILY SSF101960 60 381 2.75E-71 T 22-04-2016 HRM2_RS14500 a7a255ef34978a06f12dd59735e05416 394 PANTHER PTHR30508:SF5 30 388 1.9E-125 T 22-04-2016 HRM2_RS13675 6acd3ee70b97a3b5f931d5edca916af3 412 Gene3D G3DSA:3.40.50.10300 184 403 8.1E-82 T 22-04-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|UniPathway: UPA00241 HRM2_RS13675 6acd3ee70b97a3b5f931d5edca916af3 412 SUPERFAMILY SSF102645 182 403 2.09E-72 T 22-04-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|UniPathway: UPA00241 HRM2_RS13675 6acd3ee70b97a3b5f931d5edca916af3 412 PANTHER PTHR14359:SF20 1 404 5.2E-171 T 22-04-2016 HRM2_RS13675 6acd3ee70b97a3b5f931d5edca916af3 412 Gene3D G3DSA:3.40.50.1950 3 183 6.7E-62 T 22-04-2016 IPR003382 Flavoprotein GO:0003824 HRM2_RS13675 6acd3ee70b97a3b5f931d5edca916af3 412 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 3 400 6.1E-134 T 22-04-2016 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|UniPathway: UPA00241|UniPathway: UPA00241 HRM2_RS13675 6acd3ee70b97a3b5f931d5edca916af3 412 SUPERFAMILY SSF52507 3 178 1.26E-57 T 22-04-2016 IPR003382 Flavoprotein GO:0003824 HRM2_RS13675 6acd3ee70b97a3b5f931d5edca916af3 412 Pfam PF02441 Flavoprotein 7 131 1.4E-34 T 22-04-2016 IPR003382 Flavoprotein GO:0003824 HRM2_RS13675 6acd3ee70b97a3b5f931d5edca916af3 412 PANTHER PTHR14359 1 404 5.2E-171 T 22-04-2016 HRM2_RS13675 6acd3ee70b97a3b5f931d5edca916af3 412 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 184 374 1.9E-69 T 22-04-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|UniPathway: UPA00241 HRM2_RS08955 569238786e67fab35b12aa883c15e442 95 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 76 2.1E-8 T 22-04-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain HRM2_RS08955 569238786e67fab35b12aa883c15e442 95 Gene3D G3DSA:3.30.70.900 5 85 1.7E-11 T 22-04-2016 HRM2_RS08955 569238786e67fab35b12aa883c15e442 95 SUPERFAMILY SSF54909 2 92 3.63E-16 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel HRM2_RS05525 3d90e613bbcc0273a749fd00190a6155 295 Gene3D G3DSA:3.30.230.20 6 127 6.9E-42 T 22-04-2016 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00359 HRM2_RS05525 3d90e613bbcc0273a749fd00190a6155 295 PANTHER PTHR33694 7 283 1.1E-109 T 22-04-2016 HRM2_RS05525 3d90e613bbcc0273a749fd00190a6155 295 SUPERFAMILY SSF54211 137 278 1.52E-48 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS05525 3d90e613bbcc0273a749fd00190a6155 295 Gene3D G3DSA:3.30.1700.10 132 283 8.2E-57 T 22-04-2016 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00359 HRM2_RS05525 3d90e613bbcc0273a749fd00190a6155 295 SUPERFAMILY SSF54211 6 126 2.73E-37 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS05525 3d90e613bbcc0273a749fd00190a6155 295 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 7 276 1.1E-101 T 22-04-2016 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00359 HRM2_RS05525 3d90e613bbcc0273a749fd00190a6155 295 Hamap MF_00388 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [lpxC]. 5 281 43.369 T 22-04-2016 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00359 HRM2_RS05525 3d90e613bbcc0273a749fd00190a6155 295 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 6 287 4.3E-100 T 22-04-2016 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00359 HRM2_RS05525 3d90e613bbcc0273a749fd00190a6155 295 PANTHER PTHR33694:SF1 7 283 1.1E-109 T 22-04-2016 HRM2_RS18925 0d5c78bec01aa0190593db693863c786 436 PANTHER PTHR33362 9 436 6.2E-108 T 22-04-2016 HRM2_RS18925 0d5c78bec01aa0190593db693863c786 436 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 21 431 1.2E-93 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS18925 0d5c78bec01aa0190593db693863c786 436 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 13 425 2.2E-85 T 22-04-2016 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit HRM2_RS18925 0d5c78bec01aa0190593db693863c786 436 PIRSF PIRSF006066 5 436 1.9E-80 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS18925 0d5c78bec01aa0190593db693863c786 436 PANTHER PTHR33362:SF7 9 436 6.2E-108 T 22-04-2016 HRM2_RS16425 af605ecf85cc349b26b844a462977c58 455 SUPERFAMILY SSF55729 302 417 5.15E-18 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS16425 af605ecf85cc349b26b844a462977c58 455 PANTHER PTHR30602 12 446 1.3E-73 T 22-04-2016 HRM2_RS16425 af605ecf85cc349b26b844a462977c58 455 Pfam PF00583 Acetyltransferase (GNAT) family 345 407 6.6E-8 T 22-04-2016 IPR000182 GNAT domain GO:0008080 HRM2_RS16425 af605ecf85cc349b26b844a462977c58 455 SUPERFAMILY SSF53633 11 298 2.24E-37 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HRM2_RS16425 af605ecf85cc349b26b844a462977c58 455 PIRSF PIRSF000423 1 445 5.4E-96 T 22-04-2016 IPR010167 Amino-acid N-acetyltransferase (ArgA) GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068 HRM2_RS16425 af605ecf85cc349b26b844a462977c58 455 Hamap MF_01105 Amino-acid acetyltransferase [argA]. 1 445 91.863 T 22-04-2016 IPR010167 Amino-acid N-acetyltransferase (ArgA) GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068 HRM2_RS16425 af605ecf85cc349b26b844a462977c58 455 Gene3D G3DSA:3.40.1160.10 26 295 2.5E-51 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HRM2_RS16425 af605ecf85cc349b26b844a462977c58 455 Gene3D G3DSA:3.40.630.30 302 442 3.1E-28 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS16425 af605ecf85cc349b26b844a462977c58 455 TIGRFAM TIGR01890 N-Ac-Glu-synth: amino-acid N-acetyltransferase 12 444 5.0E-85 T 22-04-2016 IPR010167 Amino-acid N-acetyltransferase (ArgA) GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068 HRM2_RS16425 af605ecf85cc349b26b844a462977c58 455 Pfam PF00696 Amino acid kinase family 28 207 1.2E-10 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HRM2_RS24810 9f70270be809e187c6f3cce864ed9fa7 170 PANTHER PTHR30195:SF15 4 55 3.8E-13 T 22-04-2016 HRM2_RS24810 9f70270be809e187c6f3cce864ed9fa7 170 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 4 56 1.1E-14 T 22-04-2016 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 HRM2_RS24810 9f70270be809e187c6f3cce864ed9fa7 170 PANTHER PTHR30195 4 55 3.8E-13 T 22-04-2016 HRM2_RS04730 ebc52d055e0966186a6db5532246fa68 318 SUPERFAMILY SSF103481 65 163 6.15E-14 T 22-04-2016 HRM2_RS04730 ebc52d055e0966186a6db5532246fa68 318 PANTHER PTHR22911 10 306 2.1E-34 T 22-04-2016 HRM2_RS04730 ebc52d055e0966186a6db5532246fa68 318 SUPERFAMILY SSF103481 202 304 1.29E-8 T 22-04-2016 HRM2_RS04730 ebc52d055e0966186a6db5532246fa68 318 Pfam PF00892 EamA-like transporter family 28 160 9.6E-17 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS04730 ebc52d055e0966186a6db5532246fa68 318 Pfam PF00892 EamA-like transporter family 172 298 9.7E-7 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS21365 bb511f6279eea997cd7ec2487e0c4c88 1168 Gene3D G3DSA:3.40.50.300 1 87 1.8E-10 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21365 bb511f6279eea997cd7ec2487e0c4c88 1168 PANTHER PTHR41259 835 1152 6.8E-40 T 22-04-2016 HRM2_RS21365 bb511f6279eea997cd7ec2487e0c4c88 1168 PANTHER PTHR41259 1 702 6.8E-40 T 22-04-2016 HRM2_RS21365 bb511f6279eea997cd7ec2487e0c4c88 1168 Pfam PF13514 AAA domain 1 207 2.5E-72 T 22-04-2016 HRM2_RS21365 bb511f6279eea997cd7ec2487e0c4c88 1168 Gene3D G3DSA:3.40.1140.10 530 553 9.3E-8 T 22-04-2016 HRM2_RS21365 bb511f6279eea997cd7ec2487e0c4c88 1168 Gene3D G3DSA:3.40.1140.10 1081 1159 9.3E-8 T 22-04-2016 HRM2_RS21365 bb511f6279eea997cd7ec2487e0c4c88 1168 SUPERFAMILY SSF52540 1 85 2.95E-18 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21365 bb511f6279eea997cd7ec2487e0c4c88 1168 SUPERFAMILY SSF52540 1056 1156 2.95E-18 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21365 bb511f6279eea997cd7ec2487e0c4c88 1168 PANTHER PTHR41259:SF1 835 1152 6.8E-40 T 22-04-2016 HRM2_RS21365 bb511f6279eea997cd7ec2487e0c4c88 1168 PANTHER PTHR41259:SF1 1 702 6.8E-40 T 22-04-2016 HRM2_RS13040 985b2ab5672acc3ac86684cbdc8837ea 409 Gene3D G3DSA:1.10.150.130 116 204 4.6E-13 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal HRM2_RS13040 985b2ab5672acc3ac86684cbdc8837ea 409 SUPERFAMILY SSF56349 114 400 1.35E-41 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HRM2_RS13040 985b2ab5672acc3ac86684cbdc8837ea 409 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 120 194 1.6E-6 T 22-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 HRM2_RS13040 985b2ab5672acc3ac86684cbdc8837ea 409 Gene3D G3DSA:1.10.443.10 220 399 1.3E-32 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS13040 985b2ab5672acc3ac86684cbdc8837ea 409 PANTHER PTHR30349 39 399 2.3E-34 T 22-04-2016 HRM2_RS13040 985b2ab5672acc3ac86684cbdc8837ea 409 Pfam PF00589 Phage integrase family 222 393 5.1E-23 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS13040 985b2ab5672acc3ac86684cbdc8837ea 409 PANTHER PTHR30349:SF5 39 399 2.3E-34 T 22-04-2016 HRM2_RS00060 a481d68bee136128afc08ed29c482de3 1392 Pfam PF00176 SNF2 family N-terminal domain 950 1214 6.0E-55 T 22-04-2016 IPR000330 SNF2-related, N-terminal domain GO:0005524 HRM2_RS00060 a481d68bee136128afc08ed29c482de3 1392 Gene3D G3DSA:3.40.50.300 1222 1365 4.9E-19 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00060 a481d68bee136128afc08ed29c482de3 1392 SMART SM00487 932 1112 5.0E-23 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS00060 a481d68bee136128afc08ed29c482de3 1392 SUPERFAMILY SSF52540 1146 1382 8.51E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00060 a481d68bee136128afc08ed29c482de3 1392 PANTHER PTHR10799 936 1390 3.1E-169 T 22-04-2016 HRM2_RS00060 a481d68bee136128afc08ed29c482de3 1392 Gene3D G3DSA:3.40.50.300 926 1101 1.6E-20 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00060 a481d68bee136128afc08ed29c482de3 1392 SMART SM00490 1253 1335 1.4E-21 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS00060 a481d68bee136128afc08ed29c482de3 1392 SUPERFAMILY SSF52540 898 1143 2.48E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00060 a481d68bee136128afc08ed29c482de3 1392 Pfam PF00271 Helicase conserved C-terminal domain 1232 1335 6.8E-17 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS24000 0bf2939a63c979a389127c366f6168a6 914 SUPERFAMILY SSF52540 274 497 7.25E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24000 0bf2939a63c979a389127c366f6168a6 914 PANTHER PTHR24220:SF388 13 396 3.6E-223 T 22-04-2016 HRM2_RS24000 0bf2939a63c979a389127c366f6168a6 914 Pfam PF00005 ABC transporter 27 174 2.0E-25 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS24000 0bf2939a63c979a389127c366f6168a6 914 Pfam PF00005 ABC transporter 293 436 1.2E-24 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS24000 0bf2939a63c979a389127c366f6168a6 914 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS24000 0bf2939a63c979a389127c366f6168a6 914 PANTHER PTHR24220 13 396 3.6E-223 T 22-04-2016 HRM2_RS24000 0bf2939a63c979a389127c366f6168a6 914 SUPERFAMILY SSF52540 14 239 4.03E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24000 0bf2939a63c979a389127c366f6168a6 914 SMART SM00382 36 269 0.0058 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS24000 0bf2939a63c979a389127c366f6168a6 914 SMART SM00382 301 492 5.2E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS24000 0bf2939a63c979a389127c366f6168a6 914 Pfam PF12698 ABC-2 family transporter protein 572 906 1.2E-36 T 22-04-2016 HRM2_RS24000 0bf2939a63c979a389127c366f6168a6 914 Gene3D G3DSA:3.40.50.300 13 240 7.5E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24000 0bf2939a63c979a389127c366f6168a6 914 Gene3D G3DSA:3.40.50.300 274 500 6.7E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18410 2f4f5b53c0b35cb76a5e83fd14921b46 165 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 22-04-2016 IPR019776 Flagellar basal body rod protein, conserved site HRM2_RS18410 2f4f5b53c0b35cb76a5e83fd14921b46 165 PANTHER PTHR30435:SF2 1 64 1.0E-49 T 22-04-2016 HRM2_RS18410 2f4f5b53c0b35cb76a5e83fd14921b46 165 PANTHER PTHR30435:SF2 91 165 1.0E-49 T 22-04-2016 HRM2_RS18410 2f4f5b53c0b35cb76a5e83fd14921b46 165 PANTHER PTHR30435 1 64 1.0E-49 T 22-04-2016 HRM2_RS18410 2f4f5b53c0b35cb76a5e83fd14921b46 165 PANTHER PTHR30435 91 165 1.0E-49 T 22-04-2016 HRM2_RS18410 2f4f5b53c0b35cb76a5e83fd14921b46 165 Pfam PF00460 Flagella basal body rod protein 8 34 1.0E-7 T 22-04-2016 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 HRM2_RS18410 2f4f5b53c0b35cb76a5e83fd14921b46 165 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 5 165 8.6E-44 T 22-04-2016 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 HRM2_RS18410 2f4f5b53c0b35cb76a5e83fd14921b46 165 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 114 162 2.4E-9 T 22-04-2016 IPR010930 Flagellar basal-body/hook protein, C-terminal domain HRM2_RS14785 b0bdd7cec087cb9f5aa9ef37299b5cbb 258 PANTHER PTHR10859:SF94 6 241 2.0E-61 T 22-04-2016 HRM2_RS14785 b0bdd7cec087cb9f5aa9ef37299b5cbb 258 SUPERFAMILY SSF53448 4 232 3.94E-38 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS14785 b0bdd7cec087cb9f5aa9ef37299b5cbb 258 Pfam PF00535 Glycosyl transferase family 2 9 172 3.0E-22 T 22-04-2016 IPR001173 Glycosyltransferase 2-like HRM2_RS14785 b0bdd7cec087cb9f5aa9ef37299b5cbb 258 PANTHER PTHR10859 6 241 2.0E-61 T 22-04-2016 HRM2_RS14785 b0bdd7cec087cb9f5aa9ef37299b5cbb 258 Gene3D G3DSA:3.90.550.10 3 198 3.8E-18 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS04255 b82d7a5c9d6410a568c7c3465420caf5 459 Pfam PF02378 Phosphotransferase system, EIIC 21 279 3.5E-17 T 22-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 HRM2_RS04255 b82d7a5c9d6410a568c7c3465420caf5 459 PANTHER PTHR30181 3 459 3.8E-247 T 22-04-2016 HRM2_RS04255 b82d7a5c9d6410a568c7c3465420caf5 459 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 377 456 3.0E-9 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 HRM2_RS04255 b82d7a5c9d6410a568c7c3465420caf5 459 SUPERFAMILY SSF52794 376 458 3.49E-21 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 HRM2_RS04255 b82d7a5c9d6410a568c7c3465420caf5 459 Gene3D G3DSA:3.40.50.10370 373 459 7.7E-35 T 22-04-2016 IPR029503 Phosphotransferase system EIIB component, mannitol-specific GO:0009401|GO:0022872 HRM2_RS04255 b82d7a5c9d6410a568c7c3465420caf5 459 TIGRFAM TIGR00851 mtlA: PTS system, mannitol-specific IIC component 12 349 1.2E-148 T 22-04-2016 IPR004718 Phosphotransferase system, mannitol-specific enzyme IIC GO:0008982|GO:0009401|GO:0016021 HRM2_RS04255 b82d7a5c9d6410a568c7c3465420caf5 459 PANTHER PTHR30181:SF2 3 459 3.8E-247 T 22-04-2016 HRM2_RS15715 f3256cc1dee85ab9c2013422e0d420b1 202 SUPERFAMILY SSF52540 1 193 2.52E-39 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS15715 f3256cc1dee85ab9c2013422e0d420b1 202 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 198 25.409 T 22-04-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|UniPathway: UPA00241 HRM2_RS15715 f3256cc1dee85ab9c2013422e0d420b1 202 PANTHER PTHR10695 2 195 1.4E-70 T 22-04-2016 HRM2_RS15715 f3256cc1dee85ab9c2013422e0d420b1 202 Gene3D G3DSA:3.40.50.300 1 197 1.6E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS15715 f3256cc1dee85ab9c2013422e0d420b1 202 Pfam PF01121 Dephospho-CoA kinase 1 182 9.3E-56 T 22-04-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|UniPathway: UPA00241 HRM2_RS15715 f3256cc1dee85ab9c2013422e0d420b1 202 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 3 189 6.9E-53 T 22-04-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|UniPathway: UPA00241 HRM2_RS25690 9e3c0d66650a94041d01eb78826b94c2 299 Gene3D G3DSA:3.40.50.300 5 192 1.2E-36 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS25690 9e3c0d66650a94041d01eb78826b94c2 299 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 5 164 9.5E-34 T 22-04-2016 IPR003495 CobW/HypB/UreG, nucleotide-binding domain HRM2_RS25690 9e3c0d66650a94041d01eb78826b94c2 299 PANTHER PTHR13748 7 258 8.4E-35 T 22-04-2016 HRM2_RS25690 9e3c0d66650a94041d01eb78826b94c2 299 PANTHER PTHR13748:SF10 7 258 8.4E-35 T 22-04-2016 IPR012824 Cobalamin (vitamin B12) biosynthesis CobW GO:0009236 UniPathway: UPA00148 HRM2_RS25690 9e3c0d66650a94041d01eb78826b94c2 299 SUPERFAMILY SSF52540 5 166 3.23E-23 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21755 e1ea9d0b05ce417d6d8839c3a252e457 514 Pfam PF00221 Aromatic amino acid lyase 12 472 4.3E-194 T 22-04-2016 IPR001106 Aromatic amino acid lyase HRM2_RS21755 e1ea9d0b05ce417d6d8839c3a252e457 514 Gene3D G3DSA:1.20.200.10 198 508 5.4E-130 T 22-04-2016 HRM2_RS21755 e1ea9d0b05ce417d6d8839c3a252e457 514 SUPERFAMILY SSF48557 4 506 5.18E-187 T 22-04-2016 IPR008948 L-Aspartase-like GO:0003824 HRM2_RS21755 e1ea9d0b05ce417d6d8839c3a252e457 514 PANTHER PTHR10362:SF7 4 514 1.9E-235 T 22-04-2016 HRM2_RS21755 e1ea9d0b05ce417d6d8839c3a252e457 514 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 4 507 8.0E-202 T 22-04-2016 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 HRM2_RS21755 e1ea9d0b05ce417d6d8839c3a252e457 514 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 3 506 43.993 T 22-04-2016 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 HRM2_RS21755 e1ea9d0b05ce417d6d8839c3a252e457 514 Gene3D G3DSA:1.10.275.10 3 197 2.2E-68 T 22-04-2016 IPR024083 Fumarase/histidase, N-terminal HRM2_RS21755 e1ea9d0b05ce417d6d8839c3a252e457 514 PANTHER PTHR10362 4 514 1.9E-235 T 22-04-2016 HRM2_RS05805 ecf905c82dd97013d5631973659935cd 313 SUPERFAMILY SSF56770 135 269 1.16E-57 T 22-04-2016 HRM2_RS05805 ecf905c82dd97013d5631973659935cd 313 SUPERFAMILY SSF56770 3 108 1.16E-57 T 22-04-2016 HRM2_RS05805 ecf905c82dd97013d5631973659935cd 313 PANTHER PTHR11995 59 111 5.2E-41 T 22-04-2016 HRM2_RS05805 ecf905c82dd97013d5631973659935cd 313 PANTHER PTHR11995 5 41 5.2E-41 T 22-04-2016 HRM2_RS05805 ecf905c82dd97013d5631973659935cd 313 PANTHER PTHR11995 143 213 5.2E-41 T 22-04-2016 HRM2_RS05805 ecf905c82dd97013d5631973659935cd 313 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 13 172 6.8E-33 T 22-04-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 HRM2_RS05805 ecf905c82dd97013d5631973659935cd 313 PANTHER PTHR11995:SF6 59 111 5.2E-41 T 22-04-2016 HRM2_RS05805 ecf905c82dd97013d5631973659935cd 313 PANTHER PTHR11995:SF6 5 41 5.2E-41 T 22-04-2016 HRM2_RS05805 ecf905c82dd97013d5631973659935cd 313 PANTHER PTHR11995:SF6 143 213 5.2E-41 T 22-04-2016 HRM2_RS05805 ecf905c82dd97013d5631973659935cd 313 Gene3D G3DSA:3.40.50.700 3 188 1.2E-34 T 22-04-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 HRM2_RS13630 cefcdadef41b0318a6b8589706fadaff 466 Hamap MF_00006 Argininosuccinate lyase [argH]. 4 455 42.284 T 22-04-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HRM2_RS13630 cefcdadef41b0318a6b8589706fadaff 466 Gene3D G3DSA:1.20.200.10 109 375 2.7E-103 T 22-04-2016 HRM2_RS13630 cefcdadef41b0318a6b8589706fadaff 466 Pfam PF14698 Argininosuccinate lyase C-terminal 365 432 4.2E-22 T 22-04-2016 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HRM2_RS13630 cefcdadef41b0318a6b8589706fadaff 466 TIGRFAM TIGR00838 argH: argininosuccinate lyase 6 457 8.9E-191 T 22-04-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HRM2_RS13630 cefcdadef41b0318a6b8589706fadaff 466 Gene3D G3DSA:1.10.40.30 376 432 2.3E-27 T 22-04-2016 HRM2_RS13630 cefcdadef41b0318a6b8589706fadaff 466 PRINTS PR00145 Argininosuccinate lyase family signature 277 293 7.7E-67 T 22-04-2016 HRM2_RS13630 cefcdadef41b0318a6b8589706fadaff 466 PRINTS PR00145 Argininosuccinate lyase family signature 233 257 7.7E-67 T 22-04-2016 HRM2_RS13630 cefcdadef41b0318a6b8589706fadaff 466 PRINTS PR00145 Argininosuccinate lyase family signature 103 125 7.7E-67 T 22-04-2016 HRM2_RS13630 cefcdadef41b0318a6b8589706fadaff 466 PRINTS PR00145 Argininosuccinate lyase family signature 312 331 7.7E-67 T 22-04-2016 HRM2_RS13630 cefcdadef41b0318a6b8589706fadaff 466 PRINTS PR00145 Argininosuccinate lyase family signature 144 164 7.7E-67 T 22-04-2016 HRM2_RS13630 cefcdadef41b0318a6b8589706fadaff 466 PRINTS PR00145 Argininosuccinate lyase family signature 195 211 7.7E-67 T 22-04-2016 HRM2_RS13630 cefcdadef41b0318a6b8589706fadaff 466 Pfam PF00206 Lyase 8 302 5.0E-73 T 22-04-2016 IPR022761 Fumarate lyase, N-terminal HRM2_RS13630 cefcdadef41b0318a6b8589706fadaff 466 SUPERFAMILY SSF48557 6 455 1.05E-145 T 22-04-2016 IPR008948 L-Aspartase-like GO:0003824 HRM2_RS13630 cefcdadef41b0318a6b8589706fadaff 466 PANTHER PTHR11444 4 457 1.6E-227 T 22-04-2016 IPR000362 Fumarate lyase family HRM2_RS13630 cefcdadef41b0318a6b8589706fadaff 466 PANTHER PTHR11444:SF3 4 457 1.6E-227 T 22-04-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HRM2_RS13630 cefcdadef41b0318a6b8589706fadaff 466 ProSitePatterns PS00163 Fumarate lyases signature. 277 286 - T 22-04-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 HRM2_RS13630 cefcdadef41b0318a6b8589706fadaff 466 PRINTS PR00149 Fumarate lyase superfamily signature 149 167 4.6E-27 T 22-04-2016 IPR000362 Fumarate lyase family HRM2_RS13630 cefcdadef41b0318a6b8589706fadaff 466 PRINTS PR00149 Fumarate lyase superfamily signature 104 122 4.6E-27 T 22-04-2016 IPR000362 Fumarate lyase family HRM2_RS13630 cefcdadef41b0318a6b8589706fadaff 466 PRINTS PR00149 Fumarate lyase superfamily signature 233 260 4.6E-27 T 22-04-2016 IPR000362 Fumarate lyase family HRM2_RS13630 cefcdadef41b0318a6b8589706fadaff 466 PRINTS PR00149 Fumarate lyase superfamily signature 277 293 4.6E-27 T 22-04-2016 IPR000362 Fumarate lyase family HRM2_RS13630 cefcdadef41b0318a6b8589706fadaff 466 Gene3D G3DSA:1.10.275.10 4 108 1.6E-36 T 22-04-2016 IPR024083 Fumarase/histidase, N-terminal HRM2_RS19515 2850d196f11eee1b4f9933106b2397c7 82 SUPERFAMILY SSF54862 4 81 5.35E-14 T 22-04-2016 HRM2_RS19515 2850d196f11eee1b4f9933106b2397c7 82 Pfam PF12838 4Fe-4S dicluster domain 11 76 6.4E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS19515 2850d196f11eee1b4f9933106b2397c7 82 Gene3D G3DSA:3.30.70.20 4 81 2.2E-13 T 22-04-2016 HRM2_RS24035 0dfc75cfbd00c7eb0442314989a47390 127 Gene3D G3DSA:2.30.110.10 9 101 1.6E-4 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 HRM2_RS24035 0dfc75cfbd00c7eb0442314989a47390 127 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 9 74 2.1E-5 T 22-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 HRM2_RS24035 0dfc75cfbd00c7eb0442314989a47390 127 SUPERFAMILY SSF50475 9 113 4.36E-7 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 HRM2_RS13540 411f8fafe058f6bdcf30f1043bf11fe1 347 Gene3D G3DSA:3.40.50.300 34 269 1.5E-80 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13540 411f8fafe058f6bdcf30f1043bf11fe1 347 Pfam PF00154 recA bacterial DNA recombination protein 9 270 4.9E-142 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HRM2_RS13540 411f8fafe058f6bdcf30f1043bf11fe1 347 ProSitePatterns PS00321 recA signature. 215 223 - T 22-04-2016 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 HRM2_RS13540 411f8fafe058f6bdcf30f1043bf11fe1 347 SMART SM00382 59 230 3.3E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS13540 411f8fafe058f6bdcf30f1043bf11fe1 347 Hamap MF_00268 Protein RecA [recA]. 7 331 52.248 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HRM2_RS13540 411f8fafe058f6bdcf30f1043bf11fe1 347 PANTHER PTHR22942:SF1 1 337 2.6E-203 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HRM2_RS13540 411f8fafe058f6bdcf30f1043bf11fe1 347 PANTHER PTHR22942 1 337 2.6E-203 T 22-04-2016 HRM2_RS13540 411f8fafe058f6bdcf30f1043bf11fe1 347 SUPERFAMILY SSF54752 270 328 1.24E-21 T 22-04-2016 IPR023400 DNA recombination and repair protein RecA, C-terminal HRM2_RS13540 411f8fafe058f6bdcf30f1043bf11fe1 347 PRINTS PR00142 RecA protein signature 299 316 4.3E-84 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HRM2_RS13540 411f8fafe058f6bdcf30f1043bf11fe1 347 PRINTS PR00142 RecA protein signature 167 196 4.3E-84 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HRM2_RS13540 411f8fafe058f6bdcf30f1043bf11fe1 347 PRINTS PR00142 RecA protein signature 245 274 4.3E-84 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HRM2_RS13540 411f8fafe058f6bdcf30f1043bf11fe1 347 PRINTS PR00142 RecA protein signature 212 240 4.3E-84 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HRM2_RS13540 411f8fafe058f6bdcf30f1043bf11fe1 347 PRINTS PR00142 RecA protein signature 129 158 4.3E-84 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HRM2_RS13540 411f8fafe058f6bdcf30f1043bf11fe1 347 PRINTS PR00142 RecA protein signature 95 124 4.3E-84 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HRM2_RS13540 411f8fafe058f6bdcf30f1043bf11fe1 347 SUPERFAMILY SSF52540 7 269 1.3E-65 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13540 411f8fafe058f6bdcf30f1043bf11fe1 347 Gene3D G3DSA:3.30.250.10 270 328 1.4E-27 T 22-04-2016 IPR023400 DNA recombination and repair protein RecA, C-terminal HRM2_RS13540 411f8fafe058f6bdcf30f1043bf11fe1 347 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 6 326 2.0E-170 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HRM2_RS08540 4d7435687e4ed24efff6941e71df9e61 356 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 126 353 3.2E-58 T 22-04-2016 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 HRM2_RS08540 4d7435687e4ed24efff6941e71df9e61 356 SUPERFAMILY SSF50156 86 193 4.99E-18 T 22-04-2016 IPR001478 PDZ domain GO:0005515 HRM2_RS08540 4d7435687e4ed24efff6941e71df9e61 356 Gene3D G3DSA:2.30.42.10 92 193 1.7E-22 T 22-04-2016 IPR001478 PDZ domain GO:0005515 HRM2_RS08540 4d7435687e4ed24efff6941e71df9e61 356 SMART SM00228 113 183 9.5E-9 T 22-04-2016 IPR001478 PDZ domain GO:0005515 HRM2_RS08540 4d7435687e4ed24efff6941e71df9e61 356 PANTHER PTHR22939:SF78 78 93 9.2E-69 T 22-04-2016 HRM2_RS08540 4d7435687e4ed24efff6941e71df9e61 356 PANTHER PTHR22939:SF78 128 354 9.2E-69 T 22-04-2016 HRM2_RS08540 4d7435687e4ed24efff6941e71df9e61 356 Pfam PF13180 PDZ domain 128 188 2.0E-7 T 22-04-2016 IPR001478 PDZ domain GO:0005515 HRM2_RS08540 4d7435687e4ed24efff6941e71df9e61 356 Pfam PF02163 Peptidase family M50 7 340 3.5E-82 T 22-04-2016 IPR008915 Peptidase M50 GO:0004222|GO:0006508 HRM2_RS08540 4d7435687e4ed24efff6941e71df9e61 356 PANTHER PTHR22939 78 93 9.2E-69 T 22-04-2016 HRM2_RS08540 4d7435687e4ed24efff6941e71df9e61 356 PANTHER PTHR22939 128 354 9.2E-69 T 22-04-2016 HRM2_RS06890 052593989c82461bcbc77bff8b9f0d9a 490 SUPERFAMILY SSF53448 33 287 2.01E-48 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS06890 052593989c82461bcbc77bff8b9f0d9a 490 Gene3D G3DSA:3.90.550.10 43 288 6.0E-31 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS06890 052593989c82461bcbc77bff8b9f0d9a 490 Pfam PF13641 Glycosyltransferase like family 2 43 271 3.8E-29 T 22-04-2016 HRM2_RS06890 052593989c82461bcbc77bff8b9f0d9a 490 PANTHER PTHR32044 35 286 1.6E-113 T 22-04-2016 HRM2_RS06890 052593989c82461bcbc77bff8b9f0d9a 490 PANTHER PTHR32044:SF10 35 286 1.6E-113 T 22-04-2016 HRM2_RS18950 d0df214c9901b1b0502de48165d9bb16 1048 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 667 882 1.1E-21 T 22-04-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 HRM2_RS18950 d0df214c9901b1b0502de48165d9bb16 1048 Gene3D G3DSA:3.40.50.720 668 765 9.5E-27 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS18950 d0df214c9901b1b0502de48165d9bb16 1048 Gene3D G3DSA:3.40.50.720 803 965 9.5E-27 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS18950 d0df214c9901b1b0502de48165d9bb16 1048 SUPERFAMILY SSF53223 435 621 2.01E-5 T 22-04-2016 HRM2_RS18950 d0df214c9901b1b0502de48165d9bb16 1048 SUPERFAMILY SSF51735 803 929 1.51E-12 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS18950 d0df214c9901b1b0502de48165d9bb16 1048 SUPERFAMILY SSF51735 669 765 1.51E-12 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS18950 d0df214c9901b1b0502de48165d9bb16 1048 SMART SM00839 667 953 1.8E-5 T 22-04-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 HRM2_RS18950 d0df214c9901b1b0502de48165d9bb16 1048 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 356 538 1.2E-14 T 22-04-2016 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 HRM2_RS18950 d0df214c9901b1b0502de48165d9bb16 1048 PANTHER PTHR11606:SF9 187 620 8.4E-88 T 22-04-2016 HRM2_RS18950 d0df214c9901b1b0502de48165d9bb16 1048 PANTHER PTHR11606:SF9 669 1026 8.4E-88 T 22-04-2016 HRM2_RS18950 d0df214c9901b1b0502de48165d9bb16 1048 PANTHER PTHR11606 187 620 8.4E-88 T 22-04-2016 HRM2_RS18950 d0df214c9901b1b0502de48165d9bb16 1048 PANTHER PTHR11606 669 1026 8.4E-88 T 22-04-2016 HRM2_RS18910 8062cf3531ae1e6ed2970b185656beb2 525 SUPERFAMILY SSF56801 5 523 7.06E-136 T 22-04-2016 HRM2_RS18910 8062cf3531ae1e6ed2970b185656beb2 525 Pfam PF00501 AMP-binding enzyme 16 431 1.1E-89 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS18910 8062cf3531ae1e6ed2970b185656beb2 525 PANTHER PTHR24095 10 525 2.4E-206 T 22-04-2016 HRM2_RS18910 8062cf3531ae1e6ed2970b185656beb2 525 Gene3D G3DSA:3.40.50.980 185 330 6.5E-30 T 22-04-2016 HRM2_RS18910 8062cf3531ae1e6ed2970b185656beb2 525 Gene3D G3DSA:3.40.50.980 159 184 1.1E-35 T 22-04-2016 HRM2_RS18910 8062cf3531ae1e6ed2970b185656beb2 525 Gene3D G3DSA:3.40.50.980 13 122 1.1E-35 T 22-04-2016 HRM2_RS18910 8062cf3531ae1e6ed2970b185656beb2 525 ProSitePatterns PS00455 Putative AMP-binding domain signature. 174 185 - T 22-04-2016 IPR020845 AMP-binding, conserved site HRM2_RS18910 8062cf3531ae1e6ed2970b185656beb2 525 PANTHER PTHR24095:SF169 10 525 2.4E-206 T 22-04-2016 HRM2_RS18910 8062cf3531ae1e6ed2970b185656beb2 525 Pfam PF13193 AMP-binding enzyme C-terminal domain 440 514 1.6E-20 T 22-04-2016 IPR025110 AMP-binding enzyme C-terminal domain HRM2_RS18910 8062cf3531ae1e6ed2970b185656beb2 525 Gene3D G3DSA:3.30.300.30 428 523 6.9E-32 T 22-04-2016 HRM2_RS18910 8062cf3531ae1e6ed2970b185656beb2 525 Gene3D G3DSA:2.30.38.10 357 424 6.0E-19 T 22-04-2016 HRM2_RS09025 4f9dfb8d7576244fdcd7d784ae57e6e2 359 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 3 355 1.9E-91 T 22-04-2016 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 HRM2_RS09025 4f9dfb8d7576244fdcd7d784ae57e6e2 359 Pfam PF03739 Predicted permease YjgP/YjgQ family 6 354 2.6E-80 T 22-04-2016 IPR005495 Permease LptG/LptF-related GO:0016021 HRM2_RS09025 4f9dfb8d7576244fdcd7d784ae57e6e2 359 PANTHER PTHR33529 1 359 3.1E-68 T 22-04-2016 HRM2_RS05155 bc18425e916ef5c681be9f93cc321544 663 PANTHER PTHR10342:SF236 281 583 6.0E-67 T 22-04-2016 HRM2_RS05155 bc18425e916ef5c681be9f93cc321544 663 Pfam PF00884 Sulfatase 282 555 3.8E-41 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 HRM2_RS05155 bc18425e916ef5c681be9f93cc321544 663 PIRSF PIRSF005091 3 646 3.3E-86 T 22-04-2016 IPR012160 Lipoteichoic acid synthase-like KEGG: 00440+2.7.8.-|KEGG: 00513+2.7.8.-|KEGG: 00540+2.7.8.-|KEGG: 00564+2.7.8.-|KEGG: 00600+2.7.8.-|KEGG: 00770+2.7.8.-|UniPathway: UPA00556 HRM2_RS05155 bc18425e916ef5c681be9f93cc321544 663 SUPERFAMILY SSF53649 281 585 1.96E-60 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 HRM2_RS05155 bc18425e916ef5c681be9f93cc321544 663 PANTHER PTHR10342 281 583 6.0E-67 T 22-04-2016 HRM2_RS05155 bc18425e916ef5c681be9f93cc321544 663 Gene3D G3DSA:3.40.720.10 282 568 9.9E-41 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 HRM2_RS02155 5c121bff5492af5cd866e1d636b9df2f 450 TIGRFAM TIGR00115 tig: trigger factor 12 420 4.0E-104 T 22-04-2016 IPR005215 Trigger factor GO:0015031 HRM2_RS02155 5c121bff5492af5cd866e1d636b9df2f 450 SUPERFAMILY SSF109998 251 434 8.04E-34 T 22-04-2016 IPR027304 Trigger factor/SurA domain HRM2_RS02155 5c121bff5492af5cd866e1d636b9df2f 450 PIRSF PIRSF003095 1 443 2.5E-94 T 22-04-2016 IPR005215 Trigger factor GO:0015031 HRM2_RS02155 5c121bff5492af5cd866e1d636b9df2f 450 Hamap MF_00303 Trigger factor [tig]. 1 427 17.883 T 22-04-2016 IPR005215 Trigger factor GO:0015031 HRM2_RS02155 5c121bff5492af5cd866e1d636b9df2f 450 SUPERFAMILY SSF54534 88 244 2.16E-14 T 22-04-2016 HRM2_RS02155 5c121bff5492af5cd866e1d636b9df2f 450 Pfam PF05697 Bacterial trigger factor protein (TF) 1 143 2.9E-38 T 22-04-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 HRM2_RS02155 5c121bff5492af5cd866e1d636b9df2f 450 PANTHER PTHR30560 1 439 2.0E-80 T 22-04-2016 HRM2_RS02155 5c121bff5492af5cd866e1d636b9df2f 450 Gene3D G3DSA:1.10.3120.10 213 396 5.9E-39 T 22-04-2016 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 HRM2_RS02155 5c121bff5492af5cd866e1d636b9df2f 450 SUPERFAMILY SSF102735 1 130 1.29E-34 T 22-04-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 HRM2_RS02155 5c121bff5492af5cd866e1d636b9df2f 450 Gene3D G3DSA:3.30.70.1050 1 116 3.8E-33 T 22-04-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 HRM2_RS02155 5c121bff5492af5cd866e1d636b9df2f 450 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 265 422 8.2E-29 T 22-04-2016 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 HRM2_RS09925 27e99e6d0a2f20101a6c794f863d31ed 458 SUPERFAMILY SSF56801 190 351 1.1E-8 T 22-04-2016 HRM2_RS09925 27e99e6d0a2f20101a6c794f863d31ed 458 PANTHER PTHR36932 1 458 3.0E-53 T 22-04-2016 HRM2_RS09925 27e99e6d0a2f20101a6c794f863d31ed 458 PANTHER PTHR36932:SF2 1 458 3.0E-53 T 22-04-2016 HRM2_RS12330 1ae4818dcf43105f710775493871e8ba 491 SUPERFAMILY SSF51412 168 484 6.54E-117 T 22-04-2016 HRM2_RS12330 1ae4818dcf43105f710775493871e8ba 491 SMART SM01240 8 473 0.0 T 22-04-2016 HRM2_RS12330 1ae4818dcf43105f710775493871e8ba 491 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 294 306 - T 22-04-2016 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 Reactome: REACT_1698 HRM2_RS12330 1ae4818dcf43105f710775493871e8ba 491 PANTHER PTHR11911 8 281 9.0E-233 T 22-04-2016 HRM2_RS12330 1ae4818dcf43105f710775493871e8ba 491 PANTHER PTHR11911 299 485 9.0E-233 T 22-04-2016 HRM2_RS12330 1ae4818dcf43105f710775493871e8ba 491 SUPERFAMILY SSF54631 68 202 4.46E-31 T 22-04-2016 HRM2_RS12330 1ae4818dcf43105f710775493871e8ba 491 Gene3D G3DSA:3.20.20.70 6 485 2.0E-197 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS12330 1ae4818dcf43105f710775493871e8ba 491 Pfam PF00571 CBS domain 150 200 1.3E-7 T 22-04-2016 IPR000644 CBS domain HRM2_RS12330 1ae4818dcf43105f710775493871e8ba 491 Pfam PF00571 CBS domain 96 140 1.1E-11 T 22-04-2016 IPR000644 CBS domain HRM2_RS12330 1ae4818dcf43105f710775493871e8ba 491 PIRSF PIRSF000130 1 488 9.3E-204 T 22-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 HRM2_RS12330 1ae4818dcf43105f710775493871e8ba 491 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 9 473 9.2E-157 T 22-04-2016 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 Reactome: REACT_1698 HRM2_RS12330 1ae4818dcf43105f710775493871e8ba 491 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 9 486 82.548 T 22-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 HRM2_RS12330 1ae4818dcf43105f710775493871e8ba 491 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 9 455 1.6E-188 T 22-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 HRM2_RS12330 1ae4818dcf43105f710775493871e8ba 491 SMART SM00116 97 144 1.5E-12 T 22-04-2016 IPR000644 CBS domain HRM2_RS12330 1ae4818dcf43105f710775493871e8ba 491 SMART SM00116 157 205 2.0E-10 T 22-04-2016 IPR000644 CBS domain HRM2_RS12330 1ae4818dcf43105f710775493871e8ba 491 PANTHER PTHR11911:SF6 8 281 9.0E-233 T 22-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 HRM2_RS12330 1ae4818dcf43105f710775493871e8ba 491 PANTHER PTHR11911:SF6 299 485 9.0E-233 T 22-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 HRM2_RS00585 2482503f5d7eac46cc4e18a1724172f9 208 Pfam PF01810 LysE type translocator 16 205 9.8E-38 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 HRM2_RS00585 2482503f5d7eac46cc4e18a1724172f9 208 PIRSF PIRSF006324 1 208 2.3E-54 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 HRM2_RS00585 2482503f5d7eac46cc4e18a1724172f9 208 PANTHER PTHR30086:SF3 2 204 1.2E-57 T 22-04-2016 HRM2_RS00585 2482503f5d7eac46cc4e18a1724172f9 208 PANTHER PTHR30086 2 204 1.2E-57 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 HRM2_RS18710 2b8d0f09102211d50061a2dd22e0988e 453 PANTHER PTHR11206 7 436 2.5E-79 T 22-04-2016 HRM2_RS18710 2b8d0f09102211d50061a2dd22e0988e 453 TIGRFAM TIGR00797 matE: MATE efflux family protein 23 411 6.8E-59 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 HRM2_RS18710 2b8d0f09102211d50061a2dd22e0988e 453 PANTHER PTHR11206:SF132 7 436 2.5E-79 T 22-04-2016 HRM2_RS18710 2b8d0f09102211d50061a2dd22e0988e 453 Pfam PF01554 MatE 23 183 3.5E-27 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 HRM2_RS18710 2b8d0f09102211d50061a2dd22e0988e 453 Pfam PF01554 MatE 244 405 1.4E-21 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 HRM2_RS18710 2b8d0f09102211d50061a2dd22e0988e 453 PIRSF PIRSF006603 2 444 2.3E-77 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 HRM2_RS16100 296b76e682f9995e174b024decb8bdeb 322 PANTHER PTHR24220 3 220 7.1E-89 T 22-04-2016 HRM2_RS16100 296b76e682f9995e174b024decb8bdeb 322 PANTHER PTHR24220:SF523 3 220 7.1E-89 T 22-04-2016 HRM2_RS16100 296b76e682f9995e174b024decb8bdeb 322 Gene3D G3DSA:3.40.50.300 2 227 2.3E-70 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16100 296b76e682f9995e174b024decb8bdeb 322 SMART SM00382 26 207 1.1E-16 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS16100 296b76e682f9995e174b024decb8bdeb 322 SUPERFAMILY SSF52540 1 223 2.19E-65 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16100 296b76e682f9995e174b024decb8bdeb 322 Pfam PF00005 ABC transporter 17 161 1.3E-28 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS14355 0cec6bb05e6bb2a8da0ef44f33a753a0 341 Gene3D G3DSA:3.40.190.10 125 269 4.9E-17 T 22-04-2016 HRM2_RS14355 0cec6bb05e6bb2a8da0ef44f33a753a0 341 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 1 338 1.2E-53 T 22-04-2016 IPR011852 TRAP transporter solute receptor, TAXI family HRM2_RS14355 0cec6bb05e6bb2a8da0ef44f33a753a0 341 Gene3D G3DSA:3.40.190.10 34 113 6.7E-36 T 22-04-2016 HRM2_RS14355 0cec6bb05e6bb2a8da0ef44f33a753a0 341 Gene3D G3DSA:3.40.190.10 270 339 6.7E-36 T 22-04-2016 HRM2_RS14355 0cec6bb05e6bb2a8da0ef44f33a753a0 341 Pfam PF16868 NMT1-like family 40 338 1.5E-43 T 22-04-2016 IPR011852 TRAP transporter solute receptor, TAXI family HRM2_RS14355 0cec6bb05e6bb2a8da0ef44f33a753a0 341 SUPERFAMILY SSF53850 34 340 1.3E-41 T 22-04-2016 HRM2_RS14355 0cec6bb05e6bb2a8da0ef44f33a753a0 341 PANTHER PTHR30024 4 338 3.3E-20 T 22-04-2016 HRM2_RS14355 0cec6bb05e6bb2a8da0ef44f33a753a0 341 PANTHER PTHR30024:SF13 4 338 3.3E-20 T 22-04-2016 HRM2_RS06015 534242ed04f128e7ea4a089dd5e856ea 292 Pfam PF02596 Uncharacterised ArCR, COG2043 45 250 5.1E-42 T 22-04-2016 IPR003748 Protein of unknown function DUF169 HRM2_RS06425 e683116ea66023c0d34accfa6a0f0f6d 398 Gene3D G3DSA:3.40.630.10 305 396 8.6E-81 T 22-04-2016 HRM2_RS06425 e683116ea66023c0d34accfa6a0f0f6d 398 Gene3D G3DSA:3.40.630.10 10 186 8.6E-81 T 22-04-2016 HRM2_RS06425 e683116ea66023c0d34accfa6a0f0f6d 398 PANTHER PTHR11014:SF63 10 398 3.6E-117 T 22-04-2016 HRM2_RS06425 e683116ea66023c0d34accfa6a0f0f6d 398 Gene3D G3DSA:3.30.70.360 189 304 6.8E-29 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain HRM2_RS06425 e683116ea66023c0d34accfa6a0f0f6d 398 SUPERFAMILY SSF53187 15 205 1.73E-73 T 22-04-2016 HRM2_RS06425 e683116ea66023c0d34accfa6a0f0f6d 398 SUPERFAMILY SSF53187 306 395 1.73E-73 T 22-04-2016 HRM2_RS06425 e683116ea66023c0d34accfa6a0f0f6d 398 Pfam PF07687 Peptidase dimerisation domain 187 284 6.7E-11 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain HRM2_RS06425 e683116ea66023c0d34accfa6a0f0f6d 398 Pfam PF01546 Peptidase family M20/M25/M40 77 392 1.2E-27 T 22-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 HRM2_RS06425 e683116ea66023c0d34accfa6a0f0f6d 398 PIRSF PIRSF005962 6 398 3.5E-113 T 22-04-2016 IPR017439 Amidohydrolase GO:0016787 HRM2_RS06425 e683116ea66023c0d34accfa6a0f0f6d 398 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 20 383 1.1E-102 T 22-04-2016 IPR017439 Amidohydrolase GO:0016787 HRM2_RS06425 e683116ea66023c0d34accfa6a0f0f6d 398 SUPERFAMILY SSF55031 191 300 5.23E-24 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain HRM2_RS06425 e683116ea66023c0d34accfa6a0f0f6d 398 PANTHER PTHR11014 10 398 3.6E-117 T 22-04-2016 HRM2_RS23175 b3d8d18066de8254849a86f1e910d7d5 248 PANTHER PTHR23200 4 244 5.2E-44 T 22-04-2016 HRM2_RS23175 b3d8d18066de8254849a86f1e910d7d5 248 Pfam PF00753 Metallo-beta-lactamase superfamily 34 186 2.5E-17 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS23175 b3d8d18066de8254849a86f1e910d7d5 248 Gene3D G3DSA:3.60.15.10 1 242 2.5E-35 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS23175 b3d8d18066de8254849a86f1e910d7d5 248 SUPERFAMILY SSF56281 2 241 2.92E-32 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS23175 b3d8d18066de8254849a86f1e910d7d5 248 SMART SM00849 34 237 1.2E-14 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS23175 b3d8d18066de8254849a86f1e910d7d5 248 PANTHER PTHR23200:SF37 4 244 5.2E-44 T 22-04-2016 HRM2_RS18260 f786be2c4a021cf010890950bac1e129 321 Pfam PF13144 Chaperone for flagella basal body P-ring formation 123 319 8.0E-50 T 22-04-2016 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal HRM2_RS18260 f786be2c4a021cf010890950bac1e129 321 PANTHER PTHR36307 5 321 2.6E-23 T 22-04-2016 HRM2_RS18260 f786be2c4a021cf010890950bac1e129 321 TIGRFAM TIGR03170 flgA_cterm: flagella basal body P-ring formation protein FlgA 186 319 6.9E-37 T 22-04-2016 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal HRM2_RS18260 f786be2c4a021cf010890950bac1e129 321 Gene3D G3DSA:3.90.1210.10 197 259 4.6E-4 T 22-04-2016 IPR006190 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal HRM2_RS18260 f786be2c4a021cf010890950bac1e129 321 SMART SM00858 196 258 1.8E-9 T 22-04-2016 IPR013974 SAF domain HRM2_RS19815 c6d5de7e99404c805c7b1d0f2c8312dd 291 SUPERFAMILY SSF103481 210 286 1.31E-8 T 22-04-2016 HRM2_RS19815 c6d5de7e99404c805c7b1d0f2c8312dd 291 Pfam PF00892 EamA-like transporter family 12 137 7.3E-8 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS19815 c6d5de7e99404c805c7b1d0f2c8312dd 291 Pfam PF00892 EamA-like transporter family 150 285 2.0E-9 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS19815 c6d5de7e99404c805c7b1d0f2c8312dd 291 SUPERFAMILY SSF103481 39 138 1.2E-11 T 22-04-2016 HRM2_RS18265 4cf2577dde0cfdd4b7043c935a5b5188 260 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 181 257 3.5E-24 T 22-04-2016 IPR010930 Flagellar basal-body/hook protein, C-terminal domain HRM2_RS18265 4cf2577dde0cfdd4b7043c935a5b5188 260 PANTHER PTHR30435 1 260 4.3E-102 T 22-04-2016 HRM2_RS18265 4cf2577dde0cfdd4b7043c935a5b5188 260 PANTHER PTHR30435:SF19 1 260 4.3E-102 T 22-04-2016 HRM2_RS18265 4cf2577dde0cfdd4b7043c935a5b5188 260 TIGRFAM TIGR02488 flgG_G_neg: flagellar basal-body rod protein FlgG 4 256 3.9E-96 T 22-04-2016 IPR012834 Flagellar basal-body rod FlgG GO:0009426|GO:0071973 HRM2_RS18265 4cf2577dde0cfdd4b7043c935a5b5188 260 Pfam PF00460 Flagella basal body rod protein 5 35 2.0E-12 T 22-04-2016 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 HRM2_RS18265 4cf2577dde0cfdd4b7043c935a5b5188 260 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 135 3.2E-44 T 22-04-2016 IPR020013 Fagellar hook-basal body protein, FlgE/F/G HRM2_RS18265 4cf2577dde0cfdd4b7043c935a5b5188 260 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 148 241 1.2E-26 T 22-04-2016 IPR020013 Fagellar hook-basal body protein, FlgE/F/G HRM2_RS18265 4cf2577dde0cfdd4b7043c935a5b5188 260 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 22-04-2016 IPR019776 Flagellar basal body rod protein, conserved site HRM2_RS18265 4cf2577dde0cfdd4b7043c935a5b5188 260 SUPERFAMILY SSF117143 93 220 3.4E-31 T 22-04-2016 HRM2_RS23325 f2673be1f1f3fdcff0f24a4d2195b9ed 142 Pfam PF02085 Class III cytochrome C family 45 137 9.9E-16 T 22-04-2016 IPR020942 Class III cytochrome C GO:0009055|GO:0020037 HRM2_RS23325 f2673be1f1f3fdcff0f24a4d2195b9ed 142 SUPERFAMILY SSF48695 29 138 3.18E-18 T 22-04-2016 IPR011031 Multihaem cytochrome HRM2_RS23325 f2673be1f1f3fdcff0f24a4d2195b9ed 142 PRINTS PR00609 Class III cytochrome C signature 49 58 6.6E-6 T 22-04-2016 IPR002322 Cytochrome c, class III GO:0009055|GO:0020037 HRM2_RS23325 f2673be1f1f3fdcff0f24a4d2195b9ed 142 PRINTS PR00609 Class III cytochrome C signature 130 137 6.6E-6 T 22-04-2016 IPR002322 Cytochrome c, class III GO:0009055|GO:0020037 HRM2_RS23325 f2673be1f1f3fdcff0f24a4d2195b9ed 142 PRINTS PR00609 Class III cytochrome C signature 60 67 6.6E-6 T 22-04-2016 IPR002322 Cytochrome c, class III GO:0009055|GO:0020037 HRM2_RS23325 f2673be1f1f3fdcff0f24a4d2195b9ed 142 PRINTS PR00609 Class III cytochrome C signature 112 123 6.6E-6 T 22-04-2016 IPR002322 Cytochrome c, class III GO:0009055|GO:0020037 HRM2_RS23325 f2673be1f1f3fdcff0f24a4d2195b9ed 142 Gene3D G3DSA:3.90.10.10 34 137 2.1E-13 T 22-04-2016 HRM2_RS03890 08fbdc5afa380c0f310289630a69f7e3 377 PANTHER PTHR30548:SF6 16 375 9.8E-131 T 22-04-2016 HRM2_RS03890 08fbdc5afa380c0f310289630a69f7e3 377 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 32 374 3.9E-73 T 22-04-2016 IPR010327 FldB/FldC dehydratase alpha/beta subunit HRM2_RS03890 08fbdc5afa380c0f310289630a69f7e3 377 PANTHER PTHR30548 16 375 9.8E-131 T 22-04-2016 HRM2_RS21515 3832d8a7f04d8a69cf2d6fb7a3d04407 699 Gene3D G3DSA:3.30.450.20 129 207 4.2E-5 T 22-04-2016 HRM2_RS21515 3832d8a7f04d8a69cf2d6fb7a3d04407 699 SUPERFAMILY SSF58104 376 697 5.75E-63 T 22-04-2016 HRM2_RS21515 3832d8a7f04d8a69cf2d6fb7a3d04407 699 Pfam PF02743 Cache domain 56 318 1.2E-17 T 22-04-2016 IPR033479 Double Cache domain 1 HRM2_RS21515 3832d8a7f04d8a69cf2d6fb7a3d04407 699 SMART SM00283 437 698 3.2E-57 T 22-04-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HRM2_RS21515 3832d8a7f04d8a69cf2d6fb7a3d04407 699 Gene3D G3DSA:1.10.287.950 448 654 5.9E-48 T 22-04-2016 HRM2_RS21515 3832d8a7f04d8a69cf2d6fb7a3d04407 699 PANTHER PTHR32089 314 699 1.2E-100 T 22-04-2016 HRM2_RS21515 3832d8a7f04d8a69cf2d6fb7a3d04407 699 SMART SM00304 356 408 2.6E-12 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS21515 3832d8a7f04d8a69cf2d6fb7a3d04407 699 Pfam PF00672 HAMP domain 337 404 3.3E-16 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS21515 3832d8a7f04d8a69cf2d6fb7a3d04407 699 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 500 697 3.8E-37 T 22-04-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HRM2_RS21515 3832d8a7f04d8a69cf2d6fb7a3d04407 699 Gene3D G3DSA:3.30.450.20 208 334 1.4E-7 T 22-04-2016 HRM2_RS15000 23caa77a4c2a3762f48c59641bdcf463 233 SUPERFAMILY SSF53067 1 103 1.86E-21 T 22-04-2016 HRM2_RS15000 23caa77a4c2a3762f48c59641bdcf463 233 PANTHER PTHR11735:SF11 1 149 1.2E-37 T 22-04-2016 HRM2_RS15000 23caa77a4c2a3762f48c59641bdcf463 233 Gene3D G3DSA:3.30.420.40 1 132 1.9E-34 T 22-04-2016 HRM2_RS15000 23caa77a4c2a3762f48c59641bdcf463 233 PANTHER PTHR11735 1 149 1.2E-37 T 22-04-2016 HRM2_RS15000 23caa77a4c2a3762f48c59641bdcf463 233 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 217 7.1E-49 T 22-04-2016 IPR022496 tRNA threonylcarbamoyl adenosine modification protein YeaZ GO:0002949 HRM2_RS15000 23caa77a4c2a3762f48c59641bdcf463 233 Pfam PF00814 Glycoprotease family 34 156 3.0E-24 T 22-04-2016 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HRM2_RS15000 23caa77a4c2a3762f48c59641bdcf463 233 SUPERFAMILY SSF53067 110 215 6.47E-12 T 22-04-2016 HRM2_RS10690 3fb3bd7963730cad319a4c4466ca249d 181 Pfam PF01553 Acyltransferase 27 134 3.7E-8 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 HRM2_RS10690 3fb3bd7963730cad319a4c4466ca249d 181 PANTHER PTHR10434:SF9 1 141 1.6E-17 T 22-04-2016 HRM2_RS10690 3fb3bd7963730cad319a4c4466ca249d 181 SUPERFAMILY SSF69593 10 137 8.89E-13 T 22-04-2016 HRM2_RS10690 3fb3bd7963730cad319a4c4466ca249d 181 PANTHER PTHR10434 1 141 1.6E-17 T 22-04-2016 HRM2_RS10690 3fb3bd7963730cad319a4c4466ca249d 181 SMART SM00563 31 140 1.5E-7 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 HRM2_RS16310 d18980590e0f6782418802ce6a473c09 659 SUPERFAMILY SSF50249 221 597 5.14E-101 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS16310 d18980590e0f6782418802ce6a473c09 659 Pfam PF00773 RNB domain 272 554 1.3E-71 T 22-04-2016 HRM2_RS16310 d18980590e0f6782418802ce6a473c09 659 PANTHER PTHR23355 239 628 9.5E-91 T 22-04-2016 HRM2_RS16310 d18980590e0f6782418802ce6a473c09 659 SMART SM00955 272 556 7.7E-84 T 22-04-2016 HRM2_RS07335 f107886e9695b47b858e5016709355b8 393 SUPERFAMILY SSF116734 176 393 3.6E-34 T 22-04-2016 HRM2_RS07335 f107886e9695b47b858e5016709355b8 393 PANTHER PTHR30408 4 393 4.7E-42 T 22-04-2016 HRM2_RS07335 f107886e9695b47b858e5016709355b8 393 PANTHER PTHR30408:SF2 4 393 4.7E-42 T 22-04-2016 HRM2_RS07335 f107886e9695b47b858e5016709355b8 393 SUPERFAMILY SSF116734 3 191 1.18E-43 T 22-04-2016 HRM2_RS07335 f107886e9695b47b858e5016709355b8 393 Pfam PF01420 Type I restriction modification DNA specificity domain 2 173 3.8E-32 T 22-04-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 HRM2_RS07335 f107886e9695b47b858e5016709355b8 393 Pfam PF01420 Type I restriction modification DNA specificity domain 194 374 5.9E-8 T 22-04-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 HRM2_RS00095 fc758629d82e56ecc9c5135999fc7b9e 221 ProSitePatterns PS01155 Endonuclease III family signature. 106 135 - T 22-04-2016 IPR004036 Endonuclease III-like, conserved site-2 Reactome: REACT_216 HRM2_RS00095 fc758629d82e56ecc9c5135999fc7b9e 221 PIRSF PIRSF001435 5 216 8.6E-41 T 22-04-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 HRM2_RS00095 fc758629d82e56ecc9c5135999fc7b9e 221 Pfam PF00633 Helix-hairpin-helix motif 104 131 2.4E-8 T 22-04-2016 IPR000445 Helix-hairpin-helix motif GO:0003677 HRM2_RS00095 fc758629d82e56ecc9c5135999fc7b9e 221 SMART SM00478 43 189 3.8E-51 T 22-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 HRM2_RS00095 fc758629d82e56ecc9c5135999fc7b9e 221 PANTHER PTHR10359 25 208 5.8E-66 T 22-04-2016 HRM2_RS00095 fc758629d82e56ecc9c5135999fc7b9e 221 Gene3D G3DSA:1.10.340.30 30 126 7.4E-31 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 HRM2_RS00095 fc758629d82e56ecc9c5135999fc7b9e 221 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 39 173 5.9E-21 T 22-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 HRM2_RS00095 fc758629d82e56ecc9c5135999fc7b9e 221 Gene3D G3DSA:1.10.1670.10 127 210 2.3E-29 T 22-04-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal HRM2_RS00095 fc758629d82e56ecc9c5135999fc7b9e 221 SUPERFAMILY SSF48150 6 208 1.57E-56 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 HRM2_RS00720 fa588302f85328c3cf620fbfe07b3947 442 Gene3D G3DSA:1.20.200.10 116 391 4.6E-59 T 22-04-2016 HRM2_RS00720 fa588302f85328c3cf620fbfe07b3947 442 PRINTS PR00149 Fumarate lyase superfamily signature 247 274 8.5E-20 T 22-04-2016 IPR000362 Fumarate lyase family HRM2_RS00720 fa588302f85328c3cf620fbfe07b3947 442 PRINTS PR00149 Fumarate lyase superfamily signature 290 306 8.5E-20 T 22-04-2016 IPR000362 Fumarate lyase family HRM2_RS00720 fa588302f85328c3cf620fbfe07b3947 442 PRINTS PR00149 Fumarate lyase superfamily signature 111 129 8.5E-20 T 22-04-2016 IPR000362 Fumarate lyase family HRM2_RS00720 fa588302f85328c3cf620fbfe07b3947 442 PRINTS PR00149 Fumarate lyase superfamily signature 156 174 8.5E-20 T 22-04-2016 IPR000362 Fumarate lyase family HRM2_RS00720 fa588302f85328c3cf620fbfe07b3947 442 ProSitePatterns PS00163 Fumarate lyases signature. 290 299 - T 22-04-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 HRM2_RS00720 fa588302f85328c3cf620fbfe07b3947 442 Pfam PF00206 Lyase 54 311 3.7E-57 T 22-04-2016 IPR022761 Fumarate lyase, N-terminal HRM2_RS00720 fa588302f85328c3cf620fbfe07b3947 442 PRINTS PR00145 Argininosuccinate lyase family signature 247 271 8.9E-6 T 22-04-2016 HRM2_RS00720 fa588302f85328c3cf620fbfe07b3947 442 PRINTS PR00145 Argininosuccinate lyase family signature 151 171 8.9E-6 T 22-04-2016 HRM2_RS00720 fa588302f85328c3cf620fbfe07b3947 442 PRINTS PR00145 Argininosuccinate lyase family signature 290 306 8.9E-6 T 22-04-2016 HRM2_RS00720 fa588302f85328c3cf620fbfe07b3947 442 PANTHER PTHR11444 22 391 1.6E-67 T 22-04-2016 IPR000362 Fumarate lyase family HRM2_RS00720 fa588302f85328c3cf620fbfe07b3947 442 Gene3D G3DSA:1.10.275.10 3 113 7.4E-19 T 22-04-2016 IPR024083 Fumarase/histidase, N-terminal HRM2_RS00720 fa588302f85328c3cf620fbfe07b3947 442 SUPERFAMILY SSF48557 21 438 5.03E-81 T 22-04-2016 IPR008948 L-Aspartase-like GO:0003824 HRM2_RS00720 fa588302f85328c3cf620fbfe07b3947 442 PANTHER PTHR11444:SF25 22 391 1.6E-67 T 22-04-2016 HRM2_RS03805 9e53e999cf0faa4775f110bd14307eb9 496 Pfam PF00939 Sodium:sulfate symporter transmembrane region 27 482 6.4E-81 T 22-04-2016 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 HRM2_RS03805 9e53e999cf0faa4775f110bd14307eb9 496 ProSitePatterns PS01271 Sodium:sulfate symporter family signature. 430 446 - T 22-04-2016 IPR031312 Sodium/sulphate symporter, conserved site HRM2_RS03805 9e53e999cf0faa4775f110bd14307eb9 496 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 27 477 2.6E-81 T 22-04-2016 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 HRM2_RS03805 9e53e999cf0faa4775f110bd14307eb9 496 PANTHER PTHR10283 1 496 8.6E-174 T 22-04-2016 HRM2_RS03805 9e53e999cf0faa4775f110bd14307eb9 496 PANTHER PTHR10283:SF82 1 496 8.6E-174 T 22-04-2016 HRM2_RS25225 561611d54a7eb11144b4dcf5f717a562 105 Pfam PF00106 short chain dehydrogenase 2 103 4.2E-12 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS25225 561611d54a7eb11144b4dcf5f717a562 105 PANTHER PTHR24320:SF45 1 104 1.6E-26 T 22-04-2016 HRM2_RS25225 561611d54a7eb11144b4dcf5f717a562 105 Gene3D G3DSA:3.40.50.720 2 102 1.2E-19 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS25225 561611d54a7eb11144b4dcf5f717a562 105 SUPERFAMILY SSF51735 2 101 3.39E-18 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS25225 561611d54a7eb11144b4dcf5f717a562 105 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 47 63 2.9E-7 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS25225 561611d54a7eb11144b4dcf5f717a562 105 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 102 2.9E-7 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS25225 561611d54a7eb11144b4dcf5f717a562 105 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 13 2.9E-7 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS25225 561611d54a7eb11144b4dcf5f717a562 105 PANTHER PTHR24320 1 104 1.6E-26 T 22-04-2016 HRM2_RS25225 561611d54a7eb11144b4dcf5f717a562 105 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 2 13 1.5E-7 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS25225 561611d54a7eb11144b4dcf5f717a562 105 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 53 61 1.5E-7 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS25225 561611d54a7eb11144b4dcf5f717a562 105 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 102 1.5E-7 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS21120 d84c099819e6730235a777884fc56f00 145 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 9 136 5.4E-37 T 22-04-2016 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component HRM2_RS21120 d84c099819e6730235a777884fc56f00 145 PANTHER PTHR35011 1 144 1.1E-21 T 22-04-2016 HRM2_RS05560 efb730c8d42c29c645fbf48a25fb6f20 240 PANTHER PTHR38133 32 208 4.0E-41 T 22-04-2016 HRM2_RS05560 efb730c8d42c29c645fbf48a25fb6f20 240 PANTHER PTHR38133:SF1 32 208 4.0E-41 T 22-04-2016 HRM2_RS07965 34c12bf58a84a9813293fce35221b591 416 Gene3D G3DSA:3.30.450.20 226 334 1.4E-16 T 22-04-2016 HRM2_RS07965 34c12bf58a84a9813293fce35221b591 416 PANTHER PTHR32089:SF61 187 414 1.6E-21 T 22-04-2016 HRM2_RS07965 34c12bf58a84a9813293fce35221b591 416 Pfam PF02743 Cache domain 101 321 1.1E-20 T 22-04-2016 IPR033479 Double Cache domain 1 HRM2_RS07965 34c12bf58a84a9813293fce35221b591 416 SMART SM00304 359 411 3.4E-13 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS07965 34c12bf58a84a9813293fce35221b591 416 SUPERFAMILY SSF103190 132 243 1.55E-6 T 22-04-2016 IPR029151 Periplasmic sensor domain-like HRM2_RS07965 34c12bf58a84a9813293fce35221b591 416 Pfam PF00672 HAMP domain 340 406 8.2E-17 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS07965 34c12bf58a84a9813293fce35221b591 416 Gene3D G3DSA:3.30.450.20 142 225 1.0E-14 T 22-04-2016 HRM2_RS07965 34c12bf58a84a9813293fce35221b591 416 Pfam PF13717 zinc-ribbon domain 1 36 2.8E-10 T 22-04-2016 HRM2_RS07965 34c12bf58a84a9813293fce35221b591 416 PANTHER PTHR32089 187 414 1.6E-21 T 22-04-2016 HRM2_RS07965 34c12bf58a84a9813293fce35221b591 416 SUPERFAMILY SSF158472 359 407 1.83E-11 T 22-04-2016 HRM2_RS23070 2190d58b1f735e14213ea8e93683feec 530 PANTHER PTHR33525 64 335 2.5E-23 T 22-04-2016 HRM2_RS23070 2190d58b1f735e14213ea8e93683feec 530 PANTHER PTHR33525:SF3 64 335 2.5E-23 T 22-04-2016 HRM2_RS23070 2190d58b1f735e14213ea8e93683feec 530 Pfam PF08668 HDOD domain 64 248 1.1E-28 T 22-04-2016 IPR013976 Metal-dependent hydrolase HDOD HRM2_RS23070 2190d58b1f735e14213ea8e93683feec 530 SUPERFAMILY SSF55781 349 491 4.86E-6 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS23070 2190d58b1f735e14213ea8e93683feec 530 Gene3D G3DSA:3.30.450.40 348 489 2.3E-6 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS23070 2190d58b1f735e14213ea8e93683feec 530 SUPERFAMILY SSF109604 51 319 1.26E-32 T 22-04-2016 HRM2_RS23070 2190d58b1f735e14213ea8e93683feec 530 Gene3D G3DSA:1.10.3150.10 52 315 4.8E-35 T 22-04-2016 IPR013976 Metal-dependent hydrolase HDOD HRM2_RS05760 c33dd741d7f7d55cb7223d7ebb7d9368 148 PANTHER PTHR10438 49 148 2.3E-34 T 22-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 HRM2_RS05760 c33dd741d7f7d55cb7223d7ebb7d9368 148 ProSitePatterns PS00194 Thioredoxin family active site. 65 83 - T 22-04-2016 IPR017937 Thioredoxin, conserved site GO:0045454 HRM2_RS05760 c33dd741d7f7d55cb7223d7ebb7d9368 148 SUPERFAMILY SSF52833 43 148 4.63E-35 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS05760 c33dd741d7f7d55cb7223d7ebb7d9368 148 Gene3D G3DSA:3.40.30.10 45 145 1.1E-33 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS05760 c33dd741d7f7d55cb7223d7ebb7d9368 148 Pfam PF00085 Thioredoxin 46 144 3.4E-30 T 22-04-2016 IPR013766 Thioredoxin domain GO:0045454 HRM2_RS05760 c33dd741d7f7d55cb7223d7ebb7d9368 148 PRINTS PR00421 Thioredoxin family signature 72 81 6.9E-7 T 22-04-2016 HRM2_RS05760 c33dd741d7f7d55cb7223d7ebb7d9368 148 PRINTS PR00421 Thioredoxin family signature 112 123 6.9E-7 T 22-04-2016 HRM2_RS05760 c33dd741d7f7d55cb7223d7ebb7d9368 148 PRINTS PR00421 Thioredoxin family signature 64 72 6.9E-7 T 22-04-2016 HRM2_RS05760 c33dd741d7f7d55cb7223d7ebb7d9368 148 TIGRFAM TIGR01068 thioredoxin: thioredoxin 49 145 3.1E-31 T 22-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 HRM2_RS12070 7ee60266ff957d22cc8b047c96cde724 293 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 26 50 - T 22-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 HRM2_RS12070 7ee60266ff957d22cc8b047c96cde724 293 Gene3D G3DSA:3.40.1190.20 9 280 8.6E-49 T 22-04-2016 IPR029056 Ribokinase-like HRM2_RS12070 7ee60266ff957d22cc8b047c96cde724 293 Pfam PF00294 pfkB family carbohydrate kinase 21 280 5.2E-41 T 22-04-2016 IPR011611 Carbohydrate kinase PfkB HRM2_RS12070 7ee60266ff957d22cc8b047c96cde724 293 PANTHER PTHR10584:SF188 9 279 4.1E-51 T 22-04-2016 HRM2_RS12070 7ee60266ff957d22cc8b047c96cde724 293 PANTHER PTHR10584 9 279 4.1E-51 T 22-04-2016 HRM2_RS12070 7ee60266ff957d22cc8b047c96cde724 293 SUPERFAMILY SSF53613 7 280 3.59E-53 T 22-04-2016 IPR029056 Ribokinase-like HRM2_RS16140 a30fd3d92d4826e13ba960010f204748 69 PANTHER PTHR32319 5 69 9.8E-21 T 22-04-2016 HRM2_RS16140 a30fd3d92d4826e13ba960010f204748 69 SUPERFAMILY SSF55174 3 65 1.09E-17 T 22-04-2016 HRM2_RS16140 a30fd3d92d4826e13ba960010f204748 69 Gene3D G3DSA:3.10.290.10 3 67 4.4E-26 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HRM2_RS16140 a30fd3d92d4826e13ba960010f204748 69 Pfam PF13275 S4 domain 4 67 7.1E-24 T 22-04-2016 HRM2_RS16140 a30fd3d92d4826e13ba960010f204748 69 PANTHER PTHR32319:SF3 5 69 9.8E-21 T 22-04-2016 HRM2_RS13755 24d49c89113602ad7705a41addfc229d 206 Pfam PF00717 Peptidase S24-like 36 117 2.0E-19 T 22-04-2016 IPR019759 Peptidase S24/S26A/S26B HRM2_RS13755 24d49c89113602ad7705a41addfc229d 206 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 15 190 1.6E-53 T 22-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HRM2_RS13755 24d49c89113602ad7705a41addfc229d 206 ProSitePatterns PS00761 Signal peptidases I signature 3. 154 167 - T 22-04-2016 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 HRM2_RS13755 24d49c89113602ad7705a41addfc229d 206 SUPERFAMILY SSF51306 28 204 1.73E-64 T 22-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C HRM2_RS13755 24d49c89113602ad7705a41addfc229d 206 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 94 106 8.8E-21 T 22-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HRM2_RS13755 24d49c89113602ad7705a41addfc229d 206 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 30 46 8.8E-21 T 22-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HRM2_RS13755 24d49c89113602ad7705a41addfc229d 206 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 149 168 8.8E-21 T 22-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HRM2_RS13755 24d49c89113602ad7705a41addfc229d 206 Gene3D G3DSA:2.10.109.10 149 198 4.4E-53 T 22-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain HRM2_RS13755 24d49c89113602ad7705a41addfc229d 206 Gene3D G3DSA:2.10.109.10 26 104 4.4E-53 T 22-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain HRM2_RS13755 24d49c89113602ad7705a41addfc229d 206 PANTHER PTHR12383:SF27 5 194 2.1E-72 T 22-04-2016 HRM2_RS13755 24d49c89113602ad7705a41addfc229d 206 PANTHER PTHR12383 5 194 2.1E-72 T 22-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HRM2_RS10125 6eb057e560f3698b259a9c8fac528e5c 549 Gene3D G3DSA:2.30.38.10 367 442 1.2E-25 T 22-04-2016 HRM2_RS10125 6eb057e560f3698b259a9c8fac528e5c 549 Gene3D G3DSA:3.30.300.30 448 548 9.8E-29 T 22-04-2016 HRM2_RS10125 6eb057e560f3698b259a9c8fac528e5c 549 PANTHER PTHR24096 20 546 8.9E-170 T 22-04-2016 HRM2_RS10125 6eb057e560f3698b259a9c8fac528e5c 549 Pfam PF00501 AMP-binding enzyme 29 450 3.4E-108 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS10125 6eb057e560f3698b259a9c8fac528e5c 549 SUPERFAMILY SSF56801 22 547 2.62E-155 T 22-04-2016 HRM2_RS10125 6eb057e560f3698b259a9c8fac528e5c 549 ProSitePatterns PS00455 Putative AMP-binding domain signature. 202 213 - T 22-04-2016 IPR020845 AMP-binding, conserved site HRM2_RS10125 6eb057e560f3698b259a9c8fac528e5c 549 Pfam PF13193 AMP-binding enzyme C-terminal domain 460 537 1.0E-20 T 22-04-2016 IPR025110 AMP-binding enzyme C-terminal domain HRM2_RS10125 6eb057e560f3698b259a9c8fac528e5c 549 Gene3D G3DSA:3.40.50.980 208 366 5.1E-43 T 22-04-2016 HRM2_RS10125 6eb057e560f3698b259a9c8fac528e5c 549 Gene3D G3DSA:3.40.50.980 24 207 7.4E-44 T 22-04-2016 HRM2_RS13500 483902f1dc2f4af3978e04537018a03b 372 SUPERFAMILY SSF47781 5 60 1.22E-8 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 HRM2_RS13500 483902f1dc2f4af3978e04537018a03b 372 PANTHER PTHR32039 64 370 1.0E-104 T 22-04-2016 HRM2_RS13500 483902f1dc2f4af3978e04537018a03b 372 SUPERFAMILY SSF102405 84 289 8.5E-42 T 22-04-2016 HRM2_RS13500 483902f1dc2f4af3978e04537018a03b 372 Pfam PF02481 DNA recombination-mediator protein A 78 280 8.4E-75 T 22-04-2016 IPR003488 DNA recombination-mediator protein A GO:0009294 HRM2_RS13500 483902f1dc2f4af3978e04537018a03b 372 Gene3D G3DSA:1.10.150.20 12 56 2.0E-8 T 22-04-2016 HRM2_RS13500 483902f1dc2f4af3978e04537018a03b 372 PANTHER PTHR32039:SF8 64 370 1.0E-104 T 22-04-2016 HRM2_RS13500 483902f1dc2f4af3978e04537018a03b 372 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 76 289 1.9E-71 T 22-04-2016 IPR003488 DNA recombination-mediator protein A GO:0009294 HRM2_RS13500 483902f1dc2f4af3978e04537018a03b 372 Gene3D G3DSA:3.40.50.450 115 289 4.4E-13 T 22-04-2016 HRM2_RS13500 483902f1dc2f4af3978e04537018a03b 372 Gene3D G3DSA:1.10.10.10 309 361 6.8E-4 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS03750 f96617e0425fd81544e3621c4bc33659 637 PANTHER PTHR32552 1 637 3.0E-60 T 22-04-2016 HRM2_RS03750 f96617e0425fd81544e3621c4bc33659 637 SUPERFAMILY SSF56935 29 636 2.33E-126 T 22-04-2016 HRM2_RS03750 f96617e0425fd81544e3621c4bc33659 637 Gene3D G3DSA:2.40.170.20 160 636 6.3E-93 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 HRM2_RS03750 f96617e0425fd81544e3621c4bc33659 637 Pfam PF00593 TonB dependent receptor 417 631 1.1E-33 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 HRM2_RS03750 f96617e0425fd81544e3621c4bc33659 637 Pfam PF07715 TonB-dependent Receptor Plug Domain 50 153 1.0E-26 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 HRM2_RS03750 f96617e0425fd81544e3621c4bc33659 637 Gene3D G3DSA:2.170.130.10 21 159 2.0E-38 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 HRM2_RS18720 2c3dfec2d8dfdfcf479e7b1ccf25cf96 359 Gene3D G3DSA:3.40.630.30 28 157 8.3E-9 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS18720 2c3dfec2d8dfdfcf479e7b1ccf25cf96 359 SUPERFAMILY SSF55729 24 158 1.43E-12 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS01330 a4fe10dbb1d9a35d12bf2e028128a4d3 84 Pfam PF09723 Zinc ribbon domain 1 42 3.4E-14 T 22-04-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain HRM2_RS01330 a4fe10dbb1d9a35d12bf2e028128a4d3 84 SMART SM00834 1 43 5.7E-16 T 22-04-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain HRM2_RS01330 a4fe10dbb1d9a35d12bf2e028128a4d3 84 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 49 1.6E-15 T 22-04-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain HRM2_RS16065 de1e6d3308b4247715cc82fe333aece4 344 SUPERFAMILY SSF52540 1 239 6.86E-72 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16065 de1e6d3308b4247715cc82fe333aece4 344 Pfam PF08402 TOBE domain 266 343 4.0E-5 T 22-04-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 HRM2_RS16065 de1e6d3308b4247715cc82fe333aece4 344 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS16065 de1e6d3308b4247715cc82fe333aece4 344 PANTHER PTHR24220 3 273 3.4E-86 T 22-04-2016 HRM2_RS16065 de1e6d3308b4247715cc82fe333aece4 344 SUPERFAMILY SSF50331 262 343 1.46E-10 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal HRM2_RS16065 de1e6d3308b4247715cc82fe333aece4 344 Gene3D G3DSA:3.40.50.300 1 231 1.5E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16065 de1e6d3308b4247715cc82fe333aece4 344 Pfam PF00005 ABC transporter 16 158 1.1E-29 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS16065 de1e6d3308b4247715cc82fe333aece4 344 SMART SM00382 25 210 6.6E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS00130 17cd0b7fc2eb53faa96b0a8919aa179b 381 Pfam PF13458 Periplasmic binding protein 26 375 4.7E-67 T 22-04-2016 IPR028081 Leucine-binding protein domain HRM2_RS00130 17cd0b7fc2eb53faa96b0a8919aa179b 381 PANTHER PTHR30483 20 380 7.4E-84 T 22-04-2016 HRM2_RS00130 17cd0b7fc2eb53faa96b0a8919aa179b 381 PANTHER PTHR30483:SF11 20 380 7.4E-84 T 22-04-2016 HRM2_RS00130 17cd0b7fc2eb53faa96b0a8919aa179b 381 SUPERFAMILY SSF53822 26 379 1.47E-74 T 22-04-2016 IPR028082 Periplasmic binding protein-like I HRM2_RS00130 17cd0b7fc2eb53faa96b0a8919aa179b 381 Gene3D G3DSA:3.40.50.2300 25 226 6.9E-44 T 22-04-2016 HRM2_RS00545 1817823687689bc405001964cde6ec6c 106 Gene3D G3DSA:1.10.238.10 54 94 4.1E-5 T 22-04-2016 IPR011992 EF-hand domain pair HRM2_RS00545 1817823687689bc405001964cde6ec6c 106 Pfam PF13202 EF hand 77 94 6.4E-4 T 22-04-2016 IPR002048 EF-hand domain GO:0005509 HRM2_RS00545 1817823687689bc405001964cde6ec6c 106 Pfam PF13202 EF hand 55 72 2.9E-6 T 22-04-2016 IPR002048 EF-hand domain GO:0005509 HRM2_RS00545 1817823687689bc405001964cde6ec6c 106 SUPERFAMILY SSF47473 53 95 7.18E-8 T 22-04-2016 IPR011992 EF-hand domain pair HRM2_RS00545 1817823687689bc405001964cde6ec6c 106 ProSitePatterns PS00018 EF-hand calcium-binding domain. 83 95 - T 22-04-2016 IPR018247 EF-Hand 1, calcium-binding site HRM2_RS00545 1817823687689bc405001964cde6ec6c 106 ProSitePatterns PS00018 EF-hand calcium-binding domain. 60 72 - T 22-04-2016 IPR018247 EF-Hand 1, calcium-binding site HRM2_RS09930 ebfa10b852c6d0c3d5645f7febaf1b00 262 SUPERFAMILY SSF63992 1 236 3.79E-66 T 22-04-2016 IPR007035 Peptidase M55, D-aminopeptidase HRM2_RS09930 ebfa10b852c6d0c3d5645f7febaf1b00 262 Pfam PF04951 D-aminopeptidase 1 257 4.7E-67 T 22-04-2016 IPR007035 Peptidase M55, D-aminopeptidase HRM2_RS09930 ebfa10b852c6d0c3d5645f7febaf1b00 262 Gene3D G3DSA:3.40.50.10780 1 214 1.7E-57 T 22-04-2016 IPR027476 D-aminopeptidase, N-terminal HRM2_RS07425 5873b4913764aef92077b1ad1b1a2682 580 Gene3D G3DSA:1.20.58.100 440 551 8.0E-27 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 HRM2_RS07425 5873b4913764aef92077b1ad1b1a2682 580 Pfam PF00890 FAD binding domain 60 155 5.5E-11 T 22-04-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain HRM2_RS07425 5873b4913764aef92077b1ad1b1a2682 580 Pfam PF00890 FAD binding domain 168 222 1.4E-4 T 22-04-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain HRM2_RS07425 5873b4913764aef92077b1ad1b1a2682 580 Gene3D G3DSA:3.50.50.60 375 430 1.3E-40 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS07425 5873b4913764aef92077b1ad1b1a2682 580 Gene3D G3DSA:3.50.50.60 55 251 1.3E-40 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS07425 5873b4913764aef92077b1ad1b1a2682 580 SUPERFAMILY SSF46977 454 578 3.14E-25 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 HRM2_RS07425 5873b4913764aef92077b1ad1b1a2682 580 SUPERFAMILY SSF51905 376 436 6.96E-44 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS07425 5873b4913764aef92077b1ad1b1a2682 580 SUPERFAMILY SSF51905 54 256 6.96E-44 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS07425 5873b4913764aef92077b1ad1b1a2682 580 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 213 222 2.7E-8 T 22-04-2016 HRM2_RS07425 5873b4913764aef92077b1ad1b1a2682 580 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 60 82 2.7E-8 T 22-04-2016 HRM2_RS07425 5873b4913764aef92077b1ad1b1a2682 580 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 390 397 2.7E-8 T 22-04-2016 HRM2_RS07425 5873b4913764aef92077b1ad1b1a2682 580 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 375 397 3.5E-14 T 22-04-2016 HRM2_RS07425 5873b4913764aef92077b1ad1b1a2682 580 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 210 228 3.5E-14 T 22-04-2016 HRM2_RS07425 5873b4913764aef92077b1ad1b1a2682 580 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 61 80 3.5E-14 T 22-04-2016 HRM2_RS07425 5873b4913764aef92077b1ad1b1a2682 580 Pfam PF02910 Fumarate reductase flavoprotein C-term 469 578 2.1E-10 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 HRM2_RS07425 5873b4913764aef92077b1ad1b1a2682 580 PANTHER PTHR11632:SF6 50 577 2.5E-26 T 22-04-2016 HRM2_RS07425 5873b4913764aef92077b1ad1b1a2682 580 PANTHER PTHR11632 50 577 2.5E-26 T 22-04-2016 HRM2_RS01165 25f3d238853e0b9609ab88e09d84f74a 255 Pfam PF01925 Sulfite exporter TauE/SafE 11 246 3.2E-38 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 HRM2_RS01165 25f3d238853e0b9609ab88e09d84f74a 255 PANTHER PTHR30269:SF0 3 255 1.0E-67 T 22-04-2016 HRM2_RS01165 25f3d238853e0b9609ab88e09d84f74a 255 PANTHER PTHR30269 3 255 1.0E-67 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 HRM2_RS14385 61bb6393e34df929e68d49b1dd8905dd 166 Gene3D G3DSA:1.20.1260.10 2 124 8.0E-41 T 22-04-2016 IPR012347 Ferritin-related HRM2_RS14385 61bb6393e34df929e68d49b1dd8905dd 166 PANTHER PTHR33746:SF3 3 165 2.4E-59 T 22-04-2016 HRM2_RS14385 61bb6393e34df929e68d49b1dd8905dd 166 SUPERFAMILY SSF47240 2 127 1.06E-36 T 22-04-2016 IPR009078 Ferritin-like superfamily HRM2_RS14385 61bb6393e34df929e68d49b1dd8905dd 166 SUPERFAMILY SSF57802 132 164 9.6E-9 T 22-04-2016 HRM2_RS14385 61bb6393e34df929e68d49b1dd8905dd 166 Pfam PF02915 Rubrerythrin 5 119 4.3E-22 T 22-04-2016 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 HRM2_RS14385 61bb6393e34df929e68d49b1dd8905dd 166 Gene3D G3DSA:2.20.28.10 131 165 9.7E-13 T 22-04-2016 IPR004039 Rubredoxin-type fold HRM2_RS14385 61bb6393e34df929e68d49b1dd8905dd 166 PANTHER PTHR33746 3 165 2.4E-59 T 22-04-2016 HRM2_RS07175 910c0e10ee27911eb60610f20ab1bd4e 455 SUPERFAMILY SSF48310 242 318 3.14E-5 T 22-04-2016 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS07175 910c0e10ee27911eb60610f20ab1bd4e 455 SMART SM00790 9 199 4.4E-8 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS07175 910c0e10ee27911eb60610f20ab1bd4e 455 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 12 197 1.8E-33 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS07175 910c0e10ee27911eb60610f20ab1bd4e 455 Gene3D G3DSA:3.60.9.10 12 201 7.8E-26 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS07175 910c0e10ee27911eb60610f20ab1bd4e 455 SUPERFAMILY SSF56228 10 201 6.02E-21 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS07175 910c0e10ee27911eb60610f20ab1bd4e 455 PANTHER PTHR30038 4 207 7.3E-18 T 22-04-2016 HRM2_RS04195 843bffd5df99eb84f7e718b2d936ed39 264 Pfam PF00753 Metallo-beta-lactamase superfamily 25 226 1.4E-17 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS04195 843bffd5df99eb84f7e718b2d936ed39 264 Gene3D G3DSA:3.60.15.10 21 227 3.8E-34 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS04195 843bffd5df99eb84f7e718b2d936ed39 264 SMART SM00849 27 226 2.8E-17 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS04195 843bffd5df99eb84f7e718b2d936ed39 264 PANTHER PTHR11935 30 226 6.5E-15 T 22-04-2016 HRM2_RS04195 843bffd5df99eb84f7e718b2d936ed39 264 SUPERFAMILY SSF56281 20 231 3.8E-35 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS14000 cdae5e5ab0b13f1526d6a08e380e4dc5 571 PANTHER PTHR30003 1 562 2.5E-219 T 22-04-2016 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 HRM2_RS14000 cdae5e5ab0b13f1526d6a08e380e4dc5 571 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 5 554 1.8E-107 T 22-04-2016 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 HRM2_RS14000 cdae5e5ab0b13f1526d6a08e380e4dc5 571 PANTHER PTHR30003:SF4 1 562 2.5E-219 T 22-04-2016 HRM2_RS14000 cdae5e5ab0b13f1526d6a08e380e4dc5 571 Pfam PF02652 L-lactate permease 6 551 6.9E-111 T 22-04-2016 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 HRM2_RS14130 b0b19a306f01d8cc7ca13a1cba6f251b 148 Pfam PF12694 Putative molybdenum carrier 6 148 6.6E-55 T 22-04-2016 IPR024755 Molybdenum cofactor carrier, putative HRM2_RS14130 b0b19a306f01d8cc7ca13a1cba6f251b 148 SUPERFAMILY SSF102405 6 109 1.17E-5 T 22-04-2016 HRM2_RS04260 ba76367005149f402484aab45bdc0b17 331 Gene3D G3DSA:1.10.260.40 2 60 2.4E-25 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS04260 ba76367005149f402484aab45bdc0b17 331 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 2.5E-19 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 HRM2_RS04260 ba76367005149f402484aab45bdc0b17 331 Gene3D G3DSA:3.40.50.2300 61 166 1.4E-35 T 22-04-2016 HRM2_RS04260 ba76367005149f402484aab45bdc0b17 331 PANTHER PTHR30146:SF30 1 330 2.8E-111 T 22-04-2016 HRM2_RS04260 ba76367005149f402484aab45bdc0b17 331 Gene3D G3DSA:3.40.50.2300 167 330 3.7E-53 T 22-04-2016 HRM2_RS04260 ba76367005149f402484aab45bdc0b17 331 Pfam PF13377 Periplasmic binding protein-like domain 169 328 2.9E-34 T 22-04-2016 HRM2_RS04260 ba76367005149f402484aab45bdc0b17 331 SUPERFAMILY SSF53822 60 329 1.21E-73 T 22-04-2016 IPR028082 Periplasmic binding protein-like I HRM2_RS04260 ba76367005149f402484aab45bdc0b17 331 PANTHER PTHR30146 1 330 2.8E-111 T 22-04-2016 HRM2_RS04260 ba76367005149f402484aab45bdc0b17 331 SMART SM00354 1 71 2.0E-33 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 HRM2_RS04260 ba76367005149f402484aab45bdc0b17 331 SUPERFAMILY SSF47413 1 59 4.1E-18 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS04260 ba76367005149f402484aab45bdc0b17 331 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 HRM2_RS12760 c63d02db9b307101c7882fa4809bd009 452 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 8 443 27.681 T 22-04-2016 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 HRM2_RS12760 c63d02db9b307101c7882fa4809bd009 452 PANTHER PTHR30008 3 452 7.5E-153 T 22-04-2016 HRM2_RS12760 c63d02db9b307101c7882fa4809bd009 452 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 12 332 1.5E-122 T 22-04-2016 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 HRM2_RS12760 c63d02db9b307101c7882fa4809bd009 452 Pfam PF13742 OB-fold nucleic acid binding domain 11 104 2.5E-30 T 22-04-2016 IPR025824 OB-fold nucleic acid binding domain GO:0003676 HRM2_RS12760 c63d02db9b307101c7882fa4809bd009 452 PANTHER PTHR30008:SF0 3 452 7.5E-153 T 22-04-2016 HRM2_RS12760 c63d02db9b307101c7882fa4809bd009 452 Pfam PF02601 Exonuclease VII, large subunit 127 439 2.3E-88 T 22-04-2016 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 HRM2_RS09515 add55285db9b84fffeca7fd22d591d0f 91 Gene3D G3DSA:4.10.520.10 1 90 6.5E-28 T 22-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 HRM2_RS09515 add55285db9b84fffeca7fd22d591d0f 91 SUPERFAMILY SSF47729 1 90 5.0E-28 T 22-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 HRM2_RS09515 add55285db9b84fffeca7fd22d591d0f 91 PANTHER PTHR33175 1 91 9.0E-31 T 22-04-2016 HRM2_RS09515 add55285db9b84fffeca7fd22d591d0f 91 SMART SM00411 1 90 2.1E-26 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 HRM2_RS09515 add55285db9b84fffeca7fd22d591d0f 91 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.3E-11 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 HRM2_RS09515 add55285db9b84fffeca7fd22d591d0f 91 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.3E-11 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 HRM2_RS09515 add55285db9b84fffeca7fd22d591d0f 91 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 1.3E-11 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 HRM2_RS09515 add55285db9b84fffeca7fd22d591d0f 91 Pfam PF00216 Bacterial DNA-binding protein 1 89 1.2E-27 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 HRM2_RS23310 a804afd26a3d78a429905bcdfefef475 195 PANTHER PTHR11615 1 195 2.5E-53 T 22-04-2016 HRM2_RS23310 a804afd26a3d78a429905bcdfefef475 195 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 53 71 - T 22-04-2016 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 HRM2_RS23310 a804afd26a3d78a429905bcdfefef475 195 SMART SM00926 48 104 1.5E-18 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS23310 a804afd26a3d78a429905bcdfefef475 195 SUPERFAMILY SSF53706 47 195 6.28E-49 T 22-04-2016 HRM2_RS23310 a804afd26a3d78a429905bcdfefef475 195 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 49 101 8.5E-18 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS23310 a804afd26a3d78a429905bcdfefef475 195 Gene3D G3DSA:2.20.25.90 48 107 6.4E-21 T 22-04-2016 HRM2_RS23310 a804afd26a3d78a429905bcdfefef475 195 PANTHER PTHR11615:SF126 1 195 2.5E-53 T 22-04-2016 HRM2_RS23310 a804afd26a3d78a429905bcdfefef475 195 Gene3D G3DSA:3.40.50.740 109 195 9.1E-7 T 22-04-2016 HRM2_RS23310 a804afd26a3d78a429905bcdfefef475 195 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 23 3.3E-4 T 22-04-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal HRM2_RS07580 5e6cbeba40db04cbdbba93d9798e5ca3 355 SMART SM00729 61 271 2.6E-14 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS07580 5e6cbeba40db04cbdbba93d9798e5ca3 355 PIRSF PIRSF004762 7 354 3.1E-68 T 22-04-2016 IPR005244 FO synthase, subunit 2-like GO:0016765|GO:0051188|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198|UniPathway: UPA00072 HRM2_RS07580 5e6cbeba40db04cbdbba93d9798e5ca3 355 PANTHER PTHR22976 1 344 5.3E-77 T 22-04-2016 HRM2_RS07580 5e6cbeba40db04cbdbba93d9798e5ca3 355 TIGRFAM TIGR03910 pyrrolys_PylB: pyrrolysine biosynthesis radical SAM protein 7 353 4.5E-180 T 22-04-2016 IPR023891 Pyrrolysine biosynthesis protein PylB GO:0071524 KEGG: 00300+5.4.99.58|MetaCyc: PWY-6994|UniPathway: UPA00098 HRM2_RS07580 5e6cbeba40db04cbdbba93d9798e5ca3 355 PANTHER PTHR22976:SF28 1 344 5.3E-77 T 22-04-2016 HRM2_RS07580 5e6cbeba40db04cbdbba93d9798e5ca3 355 Pfam PF04055 Radical SAM superfamily 67 228 8.8E-11 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS07580 5e6cbeba40db04cbdbba93d9798e5ca3 355 Gene3D G3DSA:3.20.20.70 22 342 1.2E-66 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS07580 5e6cbeba40db04cbdbba93d9798e5ca3 355 SUPERFAMILY SSF102114 24 303 4.32E-53 T 22-04-2016 HRM2_RS15750 cbc28a404a5fb622a02f4875f8b58f5c 702 PANTHER PTHR38032 204 643 2.1E-40 T 22-04-2016 HRM2_RS15750 cbc28a404a5fb622a02f4875f8b58f5c 702 Pfam PF03961 Protein of unknown function (DUF342) 183 552 1.5E-75 T 22-04-2016 IPR005646 Protein of unknown function DUF342 HRM2_RS25255 f04a3449822aa22208a55b79d3cc0dca 617 SMART SM00304 216 268 1.3E-6 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS25255 f04a3449822aa22208a55b79d3cc0dca 617 Pfam PF00512 His Kinase A (phospho-acceptor) domain 291 356 9.4E-15 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25255 f04a3449822aa22208a55b79d3cc0dca 617 PANTHER PTHR24423 28 39 9.2E-88 T 22-04-2016 HRM2_RS25255 f04a3449822aa22208a55b79d3cc0dca 617 PANTHER PTHR24423 269 513 9.2E-88 T 22-04-2016 HRM2_RS25255 f04a3449822aa22208a55b79d3cc0dca 617 SUPERFAMILY SSF55874 345 512 2.75E-41 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25255 f04a3449822aa22208a55b79d3cc0dca 617 SUPERFAMILY SSF47384 276 357 1.37E-20 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25255 f04a3449822aa22208a55b79d3cc0dca 617 PANTHER PTHR24423:SF491 28 39 9.2E-88 T 22-04-2016 HRM2_RS25255 f04a3449822aa22208a55b79d3cc0dca 617 PANTHER PTHR24423:SF491 269 513 9.2E-88 T 22-04-2016 HRM2_RS25255 f04a3449822aa22208a55b79d3cc0dca 617 SUPERFAMILY SSF158472 222 266 3.14E-5 T 22-04-2016 HRM2_RS25255 f04a3449822aa22208a55b79d3cc0dca 617 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 404 513 5.7E-25 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25255 f04a3449822aa22208a55b79d3cc0dca 617 Pfam PF00672 HAMP domain 198 264 6.9E-9 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS25255 f04a3449822aa22208a55b79d3cc0dca 617 SMART SM00387 403 514 1.6E-32 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS25255 f04a3449822aa22208a55b79d3cc0dca 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 498 511 7.7E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25255 f04a3449822aa22208a55b79d3cc0dca 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 440 454 7.7E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25255 f04a3449822aa22208a55b79d3cc0dca 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 458 468 7.7E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25255 f04a3449822aa22208a55b79d3cc0dca 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 474 492 7.7E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS25255 f04a3449822aa22208a55b79d3cc0dca 617 SMART SM00388 290 356 7.5E-20 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25255 f04a3449822aa22208a55b79d3cc0dca 617 Gene3D G3DSA:1.10.287.130 282 352 5.5E-17 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS25255 f04a3449822aa22208a55b79d3cc0dca 617 Gene3D G3DSA:3.30.565.10 357 514 1.0E-42 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS05215 d3363101a2a1dfe78592507793d6ad1f 339 PANTHER PTHR13754:SF13 60 246 4.4E-18 T 22-04-2016 HRM2_RS05215 d3363101a2a1dfe78592507793d6ad1f 339 SUPERFAMILY SSF56281 65 306 3.28E-18 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS05215 d3363101a2a1dfe78592507793d6ad1f 339 Pfam PF00753 Metallo-beta-lactamase superfamily 77 135 4.1E-10 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS05215 d3363101a2a1dfe78592507793d6ad1f 339 PANTHER PTHR13754 60 246 4.4E-18 T 22-04-2016 HRM2_RS05215 d3363101a2a1dfe78592507793d6ad1f 339 Gene3D G3DSA:3.60.15.10 267 305 5.9E-18 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS05215 d3363101a2a1dfe78592507793d6ad1f 339 Gene3D G3DSA:3.60.15.10 76 223 5.9E-18 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS11325 47b2271b8e5c93cd00ba8f53b6cae9c2 642 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 567 8.4E-117 T 22-04-2016 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|UniPathway: UPA00134 HRM2_RS11325 47b2271b8e5c93cd00ba8f53b6cae9c2 642 Gene3D G3DSA:3.40.50.620 244 398 5.1E-63 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS11325 47b2271b8e5c93cd00ba8f53b6cae9c2 642 Gene3D G3DSA:3.40.50.620 473 632 5.1E-63 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS11325 47b2271b8e5c93cd00ba8f53b6cae9c2 642 PANTHER PTHR11772:SF10 2 404 1.2E-101 T 22-04-2016 HRM2_RS11325 47b2271b8e5c93cd00ba8f53b6cae9c2 642 PANTHER PTHR11772:SF10 469 639 1.2E-101 T 22-04-2016 HRM2_RS11325 47b2271b8e5c93cd00ba8f53b6cae9c2 642 PANTHER PTHR11772 2 404 1.2E-101 T 22-04-2016 HRM2_RS11325 47b2271b8e5c93cd00ba8f53b6cae9c2 642 PANTHER PTHR11772 469 639 1.2E-101 T 22-04-2016 HRM2_RS11325 47b2271b8e5c93cd00ba8f53b6cae9c2 642 Pfam PF00733 Asparagine synthase 261 632 9.9E-64 T 22-04-2016 IPR001962 Asparagine synthase GO:0004066|GO:0006529 HRM2_RS11325 47b2271b8e5c93cd00ba8f53b6cae9c2 642 SUPERFAMILY SSF56235 1 245 6.18E-54 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal HRM2_RS11325 47b2271b8e5c93cd00ba8f53b6cae9c2 642 PIRSF PIRSF001589 1 642 5.5E-123 T 22-04-2016 HRM2_RS11325 47b2271b8e5c93cd00ba8f53b6cae9c2 642 SUPERFAMILY SSF52402 259 402 1.2E-48 T 22-04-2016 HRM2_RS11325 47b2271b8e5c93cd00ba8f53b6cae9c2 642 SUPERFAMILY SSF52402 476 626 1.2E-48 T 22-04-2016 HRM2_RS11325 47b2271b8e5c93cd00ba8f53b6cae9c2 642 Pfam PF13537 Glutamine amidotransferase domain 69 187 2.4E-35 T 22-04-2016 IPR017932 Glutamine amidotransferase type 2 domain HRM2_RS11325 47b2271b8e5c93cd00ba8f53b6cae9c2 642 Gene3D G3DSA:3.60.20.10 1 243 2.2E-60 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal HRM2_RS17040 10642c43c50db57d84fc98f1995906cf 479 PANTHER PTHR32071:SF5 1 474 8.5E-157 T 22-04-2016 HRM2_RS17040 10642c43c50db57d84fc98f1995906cf 479 PANTHER PTHR32071 1 474 8.5E-157 T 22-04-2016 HRM2_RS17040 10642c43c50db57d84fc98f1995906cf 479 SUPERFAMILY SSF52172 1 181 1.35E-29 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS17040 10642c43c50db57d84fc98f1995906cf 479 Pfam PF00072 Response regulator receiver domain 4 108 4.7E-18 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS17040 10642c43c50db57d84fc98f1995906cf 479 Gene3D G3DSA:3.40.50.300 135 309 1.3E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17040 10642c43c50db57d84fc98f1995906cf 479 Gene3D G3DSA:3.40.50.2300 1 124 7.6E-24 T 22-04-2016 HRM2_RS17040 10642c43c50db57d84fc98f1995906cf 479 Pfam PF00158 Sigma-54 interaction domain 137 304 6.0E-65 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS17040 10642c43c50db57d84fc98f1995906cf 479 Gene3D G3DSA:1.10.10.60 416 463 1.0E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS17040 10642c43c50db57d84fc98f1995906cf 479 Gene3D G3DSA:1.10.10.60 335 379 1.0E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS17040 10642c43c50db57d84fc98f1995906cf 479 SMART SM00448 2 113 3.4E-18 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS17040 10642c43c50db57d84fc98f1995906cf 479 SMART SM00382 157 309 1.8E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS17040 10642c43c50db57d84fc98f1995906cf 479 SUPERFAMILY SSF46689 349 463 6.81E-6 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS17040 10642c43c50db57d84fc98f1995906cf 479 Pfam PF02954 Bacterial regulatory protein, Fis family 423 461 7.7E-5 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS17040 10642c43c50db57d84fc98f1995906cf 479 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 223 238 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS17040 10642c43c50db57d84fc98f1995906cf 479 SUPERFAMILY SSF52540 137 371 1.09E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21390 be463c18af85d63b78f3ee742c00de53 274 SUPERFAMILY SSF52218 4 160 5.54E-18 T 22-04-2016 IPR029039 Flavoprotein-like domain HRM2_RS21390 be463c18af85d63b78f3ee742c00de53 274 Gene3D G3DSA:3.40.50.360 2 160 6.4E-15 T 22-04-2016 IPR029039 Flavoprotein-like domain HRM2_RS21390 be463c18af85d63b78f3ee742c00de53 274 PANTHER PTHR24960 1 244 4.7E-36 T 22-04-2016 HRM2_RS21390 be463c18af85d63b78f3ee742c00de53 274 Gene3D G3DSA:3.30.70.20 200 252 2.2E-12 T 22-04-2016 HRM2_RS21390 be463c18af85d63b78f3ee742c00de53 274 Pfam PF00037 4Fe-4S binding domain 201 218 1.1E-4 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS21390 be463c18af85d63b78f3ee742c00de53 274 PANTHER PTHR24960:SF20 1 244 4.7E-36 T 22-04-2016 HRM2_RS21390 be463c18af85d63b78f3ee742c00de53 274 SUPERFAMILY SSF54862 201 265 1.34E-15 T 22-04-2016 HRM2_RS21390 be463c18af85d63b78f3ee742c00de53 274 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 203 214 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS01100 2f92bb6aa3693aaaf80e46e2c78b85e2 393 PANTHER PTHR37477:SF1 91 387 1.5E-57 T 22-04-2016 HRM2_RS01100 2f92bb6aa3693aaaf80e46e2c78b85e2 393 Gene3D G3DSA:3.30.420.180 251 380 2.2E-38 T 22-04-2016 IPR002750 CobE/GbiG C-terminal domain GO:0009236 HRM2_RS01100 2f92bb6aa3693aaaf80e46e2c78b85e2 393 Pfam PF01890 Cobalamin synthesis G C-terminus 260 378 4.0E-34 T 22-04-2016 IPR002750 CobE/GbiG C-terminal domain GO:0009236 HRM2_RS01100 2f92bb6aa3693aaaf80e46e2c78b85e2 393 Pfam PF11760 Cobalamin synthesis G N-terminal 90 170 7.1E-34 T 22-04-2016 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377|UniPathway: UPA00148 HRM2_RS01100 2f92bb6aa3693aaaf80e46e2c78b85e2 393 SUPERFAMILY SSF159664 253 380 1.44E-37 T 22-04-2016 IPR002750 CobE/GbiG C-terminal domain GO:0009236 HRM2_RS01100 2f92bb6aa3693aaaf80e46e2c78b85e2 393 SUPERFAMILY SSF159672 81 267 4.84E-58 T 22-04-2016 HRM2_RS01100 2f92bb6aa3693aaaf80e46e2c78b85e2 393 SUPERFAMILY SSF159672 13 42 4.84E-58 T 22-04-2016 HRM2_RS01100 2f92bb6aa3693aaaf80e46e2c78b85e2 393 Pfam PF11761 Cobalamin biosynthesis central region 175 216 2.5E-5 T 22-04-2016 IPR021745 Cobalamin biosynthesis central region KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377|UniPathway: UPA00148 HRM2_RS01100 2f92bb6aa3693aaaf80e46e2c78b85e2 393 PANTHER PTHR37477 91 387 1.5E-57 T 22-04-2016 HRM2_RS10755 b9122be78c4838d755f6e35507618745 589 PANTHER PTHR30252 1 559 3.2E-181 T 22-04-2016 HRM2_RS10755 b9122be78c4838d755f6e35507618745 589 Pfam PF02554 Carbon starvation protein CstA 1 350 4.5E-112 T 22-04-2016 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 HRM2_RS10755 b9122be78c4838d755f6e35507618745 589 PANTHER PTHR30252:SF0 1 559 3.2E-181 T 22-04-2016 HRM2_RS10755 b9122be78c4838d755f6e35507618745 589 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 407 526 9.4E-33 T 22-04-2016 IPR025299 CstA, C-terminal domain HRM2_RS07430 a3991c2df2b0d82ce1efc62559d441cb 388 PANTHER PTHR23502:SF19 1 358 4.5E-70 T 22-04-2016 HRM2_RS07430 a3991c2df2b0d82ce1efc62559d441cb 388 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 3 373 5.3E-72 T 22-04-2016 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 HRM2_RS07430 a3991c2df2b0d82ce1efc62559d441cb 388 PANTHER PTHR23502 1 358 4.5E-70 T 22-04-2016 HRM2_RS07430 a3991c2df2b0d82ce1efc62559d441cb 388 Gene3D G3DSA:1.20.1250.20 196 378 2.3E-8 T 22-04-2016 HRM2_RS07430 a3991c2df2b0d82ce1efc62559d441cb 388 Gene3D G3DSA:1.20.1250.20 3 177 3.2E-33 T 22-04-2016 HRM2_RS07430 a3991c2df2b0d82ce1efc62559d441cb 388 Pfam PF07690 Major Facilitator Superfamily 7 343 8.9E-49 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS07430 a3991c2df2b0d82ce1efc62559d441cb 388 SUPERFAMILY SSF103473 2 376 1.29E-60 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS24450 e20797db38528f9edce06111a03bfdab 204 Pfam PF04381 Putative exonuclease, RdgC 13 170 1.0E-12 T 22-04-2016 IPR007476 Putative exonuclease, RdgC GO:0006310 HRM2_RS08175 ee3263cfdf744f95619e532792b7d1e9 103 PANTHER PTHR33449:SF1 3 103 2.5E-43 T 22-04-2016 HRM2_RS08175 ee3263cfdf744f95619e532792b7d1e9 103 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 3 102 9.4E-28 T 22-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family HRM2_RS08175 ee3263cfdf744f95619e532792b7d1e9 103 PIRSF PIRSF004555 1 103 3.2E-38 T 22-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family HRM2_RS08175 ee3263cfdf744f95619e532792b7d1e9 103 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 2 96 21.848 T 22-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family HRM2_RS08175 ee3263cfdf744f95619e532792b7d1e9 103 Pfam PF02575 YbaB/EbfC DNA-binding family 8 98 7.4E-34 T 22-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family HRM2_RS08175 ee3263cfdf744f95619e532792b7d1e9 103 Gene3D G3DSA:3.30.1310.10 2 103 6.2E-39 T 22-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family HRM2_RS08175 ee3263cfdf744f95619e532792b7d1e9 103 SUPERFAMILY SSF82607 8 102 9.81E-33 T 22-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family HRM2_RS08175 ee3263cfdf744f95619e532792b7d1e9 103 PANTHER PTHR33449 3 103 2.5E-43 T 22-04-2016 HRM2_RS10160 942ed54f7b55f7bf12cd649e9e70f724 143 SUPERFAMILY SSF47188 4 132 1.96E-26 T 22-04-2016 IPR012827 Haemerythrin, metal-binding domain GO:0046872 HRM2_RS10160 942ed54f7b55f7bf12cd649e9e70f724 143 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 8 132 7.6E-30 T 22-04-2016 IPR012827 Haemerythrin, metal-binding domain GO:0046872 HRM2_RS10160 942ed54f7b55f7bf12cd649e9e70f724 143 Pfam PF01814 Hemerythrin HHE cation binding domain 24 131 5.0E-6 T 22-04-2016 IPR012312 Haemerythrin-like HRM2_RS10160 942ed54f7b55f7bf12cd649e9e70f724 143 Gene3D G3DSA:1.20.120.50 4 132 3.3E-29 T 22-04-2016 IPR012827 Haemerythrin, metal-binding domain GO:0046872 HRM2_RS10160 942ed54f7b55f7bf12cd649e9e70f724 143 PANTHER PTHR37164 5 133 4.1E-24 T 22-04-2016 HRM2_RS00085 ae2f627a00b7f254799c3dc489ba2382 465 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 5 455 1.6E-144 T 22-04-2016 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 HRM2_RS00085 ae2f627a00b7f254799c3dc489ba2382 465 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 1 445 42.686 T 22-04-2016 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 HRM2_RS00085 ae2f627a00b7f254799c3dc489ba2382 465 PANTHER PTHR21343:SF6 1 459 1.1E-170 T 22-04-2016 HRM2_RS00085 ae2f627a00b7f254799c3dc489ba2382 465 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 247 443 3.3E-38 T 22-04-2016 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 UniPathway: UPA00148 HRM2_RS00085 ae2f627a00b7f254799c3dc489ba2382 465 Gene3D G3DSA:3.40.50.300 2 193 7.4E-28 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00085 ae2f627a00b7f254799c3dc489ba2382 465 Gene3D G3DSA:3.40.50.880 246 455 4.8E-27 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS00085 ae2f627a00b7f254799c3dc489ba2382 465 PANTHER PTHR21343 1 459 1.1E-170 T 22-04-2016 HRM2_RS00085 ae2f627a00b7f254799c3dc489ba2382 465 SUPERFAMILY SSF52317 243 443 4.76E-31 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS00085 ae2f627a00b7f254799c3dc489ba2382 465 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 193 7.5E-24 T 22-04-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain HRM2_RS00085 ae2f627a00b7f254799c3dc489ba2382 465 SUPERFAMILY SSF52540 2 195 2.11E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08030 8679f2fc00af49e41288ec728d378952 355 Pfam PF01497 Periplasmic binding protein 101 285 1.6E-15 T 22-04-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 HRM2_RS08030 8679f2fc00af49e41288ec728d378952 355 Gene3D G3DSA:3.40.50.1980 165 323 1.3E-25 T 22-04-2016 HRM2_RS08030 8679f2fc00af49e41288ec728d378952 355 PANTHER PTHR30535 1 346 1.0E-49 T 22-04-2016 HRM2_RS08030 8679f2fc00af49e41288ec728d378952 355 Gene3D G3DSA:3.40.50.1980 30 162 2.3E-9 T 22-04-2016 HRM2_RS08030 8679f2fc00af49e41288ec728d378952 355 PANTHER PTHR30535:SF16 1 346 1.0E-49 T 22-04-2016 HRM2_RS08030 8679f2fc00af49e41288ec728d378952 355 SUPERFAMILY SSF53807 36 346 2.2E-53 T 22-04-2016 HRM2_RS19875 c18e0e7c65b171d722b8ca07b94891e6 142 Gene3D G3DSA:3.40.50.2300 4 132 2.4E-35 T 22-04-2016 HRM2_RS19875 c18e0e7c65b171d722b8ca07b94891e6 142 PANTHER PTHR26402 3 141 1.6E-31 T 22-04-2016 HRM2_RS19875 c18e0e7c65b171d722b8ca07b94891e6 142 SUPERFAMILY SSF52172 4 128 6.97E-36 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS19875 c18e0e7c65b171d722b8ca07b94891e6 142 PANTHER PTHR26402:SF471 3 141 1.6E-31 T 22-04-2016 HRM2_RS19875 c18e0e7c65b171d722b8ca07b94891e6 142 SMART SM00448 3 114 9.1E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS19875 c18e0e7c65b171d722b8ca07b94891e6 142 Pfam PF00072 Response regulator receiver domain 5 115 1.3E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS06430 66a5c1f64bce86da25ffb47a8537e316 264 PANTHER PTHR30136 1 260 6.5E-37 T 22-04-2016 HRM2_RS06430 66a5c1f64bce86da25ffb47a8537e316 264 Gene3D G3DSA:3.30.450.40 97 248 6.6E-27 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS06430 66a5c1f64bce86da25ffb47a8537e316 264 PANTHER PTHR30136:SF3 1 260 6.5E-37 T 22-04-2016 HRM2_RS06430 66a5c1f64bce86da25ffb47a8537e316 264 Pfam PF09339 IclR helix-turn-helix domain 22 74 8.0E-12 T 22-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 HRM2_RS06430 66a5c1f64bce86da25ffb47a8537e316 264 Pfam PF01614 Bacterial transcriptional regulator 143 249 4.4E-13 T 22-04-2016 IPR014757 Transcription regulator IclR, C-terminal HRM2_RS06430 66a5c1f64bce86da25ffb47a8537e316 264 Gene3D G3DSA:1.10.10.10 18 90 2.5E-15 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS06430 66a5c1f64bce86da25ffb47a8537e316 264 SMART SM00346 20 110 2.5E-10 T 22-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 HRM2_RS06430 66a5c1f64bce86da25ffb47a8537e316 264 SUPERFAMILY SSF46785 21 89 7.4E-12 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS06430 66a5c1f64bce86da25ffb47a8537e316 264 SUPERFAMILY SSF55781 96 260 2.22E-28 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS01750 4728ee7334f30b0f75f85c8811de382b 468 Pfam PF06751 Ethanolamine ammonia lyase large subunit (EutB) 18 452 3.8E-219 T 22-04-2016 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7|UniPathway: UPA00560 HRM2_RS01750 4728ee7334f30b0f75f85c8811de382b 468 PANTHER PTHR39329 7 465 2.4E-268 T 22-04-2016 HRM2_RS01750 4728ee7334f30b0f75f85c8811de382b 468 Gene3D G3DSA:2.30.170.30 8 60 4.3E-22 T 22-04-2016 HRM2_RS01750 4728ee7334f30b0f75f85c8811de382b 468 PANTHER PTHR39329:SF1 7 465 2.4E-268 T 22-04-2016 HRM2_RS01750 4728ee7334f30b0f75f85c8811de382b 468 PIRSF PIRSF018788 7 463 2.2E-232 T 22-04-2016 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7|UniPathway: UPA00560 HRM2_RS01750 4728ee7334f30b0f75f85c8811de382b 468 Gene3D G3DSA:3.20.20.70 149 452 1.6E-161 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS01750 4728ee7334f30b0f75f85c8811de382b 468 Gene3D G3DSA:1.10.220.70 62 147 6.4E-39 T 22-04-2016 HRM2_RS09970 db3980c2d70b68644f8a472d14387850 271 Pfam PF00665 Integrase core domain 113 222 2.6E-22 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 HRM2_RS09970 db3980c2d70b68644f8a472d14387850 271 SUPERFAMILY SSF53098 114 264 5.01E-36 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS09970 db3980c2d70b68644f8a472d14387850 271 Gene3D G3DSA:3.30.420.10 109 260 1.0E-31 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS09970 db3980c2d70b68644f8a472d14387850 271 PANTHER PTHR32552 7 260 3.2E-24 T 22-04-2016 HRM2_RS09970 db3980c2d70b68644f8a472d14387850 271 Pfam PF13276 HTH-like domain 38 89 1.9E-12 T 22-04-2016 IPR025948 HTH-like domain HRM2_RS17175 db3980c2d70b68644f8a472d14387850 271 Pfam PF00665 Integrase core domain 113 222 2.6E-22 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 HRM2_RS17175 db3980c2d70b68644f8a472d14387850 271 SUPERFAMILY SSF53098 114 264 5.01E-36 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS17175 db3980c2d70b68644f8a472d14387850 271 Gene3D G3DSA:3.30.420.10 109 260 1.0E-31 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS17175 db3980c2d70b68644f8a472d14387850 271 PANTHER PTHR32552 7 260 3.2E-24 T 22-04-2016 HRM2_RS17175 db3980c2d70b68644f8a472d14387850 271 Pfam PF13276 HTH-like domain 38 89 1.9E-12 T 22-04-2016 IPR025948 HTH-like domain HRM2_RS04780 03640a7f60a4524c693f3e34203fead2 460 ProSitePatterns PS00699 Nitrogenases component 1 alpha and beta subunits signature 1. 42 49 - T 22-04-2016 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 HRM2_RS04780 03640a7f60a4524c693f3e34203fead2 460 Gene3D G3DSA:3.40.50.1980 24 164 1.2E-49 T 22-04-2016 HRM2_RS04780 03640a7f60a4524c693f3e34203fead2 460 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 24 443 1.7E-117 T 22-04-2016 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 HRM2_RS04780 03640a7f60a4524c693f3e34203fead2 460 PANTHER PTHR33712:SF7 13 204 9.3E-128 T 22-04-2016 HRM2_RS04780 03640a7f60a4524c693f3e34203fead2 460 PANTHER PTHR33712:SF7 223 460 9.3E-128 T 22-04-2016 HRM2_RS04780 03640a7f60a4524c693f3e34203fead2 460 SUPERFAMILY SSF53807 5 459 6.54E-146 T 22-04-2016 HRM2_RS04780 03640a7f60a4524c693f3e34203fead2 460 Gene3D G3DSA:3.40.50.1980 296 419 1.1E-46 T 22-04-2016 HRM2_RS04780 03640a7f60a4524c693f3e34203fead2 460 PANTHER PTHR33712 13 204 9.3E-128 T 22-04-2016 HRM2_RS04780 03640a7f60a4524c693f3e34203fead2 460 PANTHER PTHR33712 223 460 9.3E-128 T 22-04-2016 HRM2_RS04780 03640a7f60a4524c693f3e34203fead2 460 TIGRFAM TIGR01286 nifK: nitrogenase molybdenum-iron protein beta chain 12 452 6.4E-130 T 22-04-2016 IPR005976 Nitrogenase molybdenum-iron protein beta chain GO:0009399|GO:0016163|GO:0016612|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 HRM2_RS04780 03640a7f60a4524c693f3e34203fead2 460 Gene3D G3DSA:3.40.50.1980 167 269 2.8E-35 T 22-04-2016 HRM2_RS02955 ff50906d47768125db96936afa65a024 343 Gene3D G3DSA:3.40.50.1970 23 159 5.6E-46 T 22-04-2016 HRM2_RS02955 ff50906d47768125db96936afa65a024 343 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 29 330 1.1E-101 T 22-04-2016 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 HRM2_RS02955 ff50906d47768125db96936afa65a024 343 SUPERFAMILY SSF56796 19 339 4.71E-89 T 22-04-2016 HRM2_RS02955 ff50906d47768125db96936afa65a024 343 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 339 34.16 T 22-04-2016 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 HRM2_RS02955 ff50906d47768125db96936afa65a024 343 Pfam PF01761 3-dehydroquinate synthase 54 307 1.7E-89 T 22-04-2016 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 HRM2_RS02955 ff50906d47768125db96936afa65a024 343 PIRSF PIRSF001455 11 341 4.5E-104 T 22-04-2016 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 HRM2_RS02955 ff50906d47768125db96936afa65a024 343 Gene3D G3DSA:1.20.1090.10 160 337 4.9E-56 T 22-04-2016 HRM2_RS02955 ff50906d47768125db96936afa65a024 343 PANTHER PTHR21090 30 335 3.7E-115 T 22-04-2016 HRM2_RS01460 a97f3d759754fe7b7d0d875e221cd77a 329 PANTHER PTHR10909:SF309 201 317 1.7E-28 T 22-04-2016 HRM2_RS01460 a97f3d759754fe7b7d0d875e221cd77a 329 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 201 284 2.8E-29 T 22-04-2016 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal HRM2_RS01460 a97f3d759754fe7b7d0d875e221cd77a 329 SUPERFAMILY SSF52467 201 317 6.34E-37 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HRM2_RS01460 a97f3d759754fe7b7d0d875e221cd77a 329 Pfam PF01012 Electron transfer flavoprotein domain 6 165 4.3E-23 T 22-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 HRM2_RS01460 a97f3d759754fe7b7d0d875e221cd77a 329 SMART SM00893 4 189 2.5E-15 T 22-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 HRM2_RS01460 a97f3d759754fe7b7d0d875e221cd77a 329 Gene3D G3DSA:3.40.50.1220 194 316 4.7E-43 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HRM2_RS01460 a97f3d759754fe7b7d0d875e221cd77a 329 SUPERFAMILY SSF52402 3 192 3.07E-30 T 22-04-2016 HRM2_RS01460 a97f3d759754fe7b7d0d875e221cd77a 329 PIRSF PIRSF000089 1 324 1.3E-71 T 22-04-2016 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 HRM2_RS01460 a97f3d759754fe7b7d0d875e221cd77a 329 Gene3D G3DSA:3.40.50.620 4 188 3.1E-30 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS01460 a97f3d759754fe7b7d0d875e221cd77a 329 PANTHER PTHR10909 201 317 1.7E-28 T 22-04-2016 HRM2_RS18915 73779276cc7633f5c62ff8075df970cb 216 PANTHER PTHR11751 4 89 3.0E-20 T 22-04-2016 HRM2_RS18915 73779276cc7633f5c62ff8075df970cb 216 Gene3D G3DSA:1.20.120.530 68 165 4.6E-13 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS18915 73779276cc7633f5c62ff8075df970cb 216 SMART SM00345 5 63 7.1E-10 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS18915 73779276cc7633f5c62ff8075df970cb 216 SUPERFAMILY SSF48008 69 189 6.28E-11 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS18915 73779276cc7633f5c62ff8075df970cb 216 Pfam PF07729 FCD domain 74 168 1.2E-12 T 22-04-2016 IPR011711 GntR, C-terminal HRM2_RS18915 73779276cc7633f5c62ff8075df970cb 216 SUPERFAMILY SSF46785 3 67 2.88E-15 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS18915 73779276cc7633f5c62ff8075df970cb 216 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 63 3.5E-15 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS18915 73779276cc7633f5c62ff8075df970cb 216 Gene3D G3DSA:1.10.10.10 3 64 6.7E-18 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS15495 ee3355c80d223cbba94a7272d70f4a6f 115 PANTHER PTHR34535 2 113 8.0E-31 T 22-04-2016 HRM2_RS15495 ee3355c80d223cbba94a7272d70f4a6f 115 PANTHER PTHR34535:SF3 2 113 8.0E-31 T 22-04-2016 HRM2_RS15495 ee3355c80d223cbba94a7272d70f4a6f 115 Hamap MF_00213 Probable hydrogenase nickel incorporation protein HypA [hypA]. 1 114 21.7 T 22-04-2016 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 HRM2_RS15495 ee3355c80d223cbba94a7272d70f4a6f 115 PIRSF PIRSF004761 1 115 3.2E-28 T 22-04-2016 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 HRM2_RS15495 ee3355c80d223cbba94a7272d70f4a6f 115 TIGRFAM TIGR00100 hypA: hydrogenase nickel insertion protein HypA 1 113 3.1E-26 T 22-04-2016 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 HRM2_RS15495 ee3355c80d223cbba94a7272d70f4a6f 115 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 112 3.7E-30 T 22-04-2016 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 HRM2_RS02820 25ffd7c8d15258a34055be1a3d786355 407 PANTHER PTHR30572 15 365 8.5E-90 T 22-04-2016 HRM2_RS02820 25ffd7c8d15258a34055be1a3d786355 407 SUPERFAMILY SSF111369 58 291 7.98E-30 T 22-04-2016 HRM2_RS02820 25ffd7c8d15258a34055be1a3d786355 407 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 67 288 2.0E-22 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain HRM2_RS02820 25ffd7c8d15258a34055be1a3d786355 407 Gene3D G3DSA:2.40.50.100 176 207 6.4E-19 T 22-04-2016 HRM2_RS02820 25ffd7c8d15258a34055be1a3d786355 407 Gene3D G3DSA:2.40.50.100 67 101 6.4E-19 T 22-04-2016 HRM2_RS02820 25ffd7c8d15258a34055be1a3d786355 407 PANTHER PTHR30572:SF1 15 365 8.5E-90 T 22-04-2016 HRM2_RS02820 25ffd7c8d15258a34055be1a3d786355 407 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 45 362 9.8E-59 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 HRM2_RS13005 beaf82eedba1483ec2a252cab4345e0e 276 PANTHER PTHR11935 38 209 8.6E-18 T 22-04-2016 HRM2_RS13005 beaf82eedba1483ec2a252cab4345e0e 276 SMART SM00849 29 198 6.4E-21 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS13005 beaf82eedba1483ec2a252cab4345e0e 276 SUPERFAMILY SSF56281 36 256 1.7E-39 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS13005 beaf82eedba1483ec2a252cab4345e0e 276 Pfam PF00753 Metallo-beta-lactamase superfamily 37 198 3.5E-15 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS13005 beaf82eedba1483ec2a252cab4345e0e 276 Gene3D G3DSA:3.60.15.10 37 219 9.0E-32 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS11435 3c6695ae9f8e53037e2f434f6a5ac1cf 555 Pfam PF00691 OmpA family 452 546 1.1E-14 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS11435 3c6695ae9f8e53037e2f434f6a5ac1cf 555 SMART SM00382 42 189 5.0E-5 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS11435 3c6695ae9f8e53037e2f434f6a5ac1cf 555 PANTHER PTHR35894 2 277 7.4E-74 T 22-04-2016 HRM2_RS11435 3c6695ae9f8e53037e2f434f6a5ac1cf 555 Pfam PF13401 AAA domain 42 170 5.2E-19 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS11435 3c6695ae9f8e53037e2f434f6a5ac1cf 555 PRINTS PR01021 OMPA domain signature 452 474 7.0E-9 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 HRM2_RS11435 3c6695ae9f8e53037e2f434f6a5ac1cf 555 PRINTS PR01021 OMPA domain signature 482 497 7.0E-9 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 HRM2_RS11435 3c6695ae9f8e53037e2f434f6a5ac1cf 555 PRINTS PR01021 OMPA domain signature 497 513 7.0E-9 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 HRM2_RS11435 3c6695ae9f8e53037e2f434f6a5ac1cf 555 PANTHER PTHR35894:SF1 2 277 7.4E-74 T 22-04-2016 HRM2_RS11435 3c6695ae9f8e53037e2f434f6a5ac1cf 555 SUPERFAMILY SSF103088 437 552 7.06E-29 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS11435 3c6695ae9f8e53037e2f434f6a5ac1cf 555 Gene3D G3DSA:3.30.1330.60 439 552 1.2E-29 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS11435 3c6695ae9f8e53037e2f434f6a5ac1cf 555 Gene3D G3DSA:3.40.50.300 26 182 2.7E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11435 3c6695ae9f8e53037e2f434f6a5ac1cf 555 SUPERFAMILY SSF52540 6 259 5.58E-30 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17860 a706f9d5d11b6681ebf7f80368a2f281 65 Gene3D G3DSA:1.10.287.310 1 64 2.5E-27 T 22-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17860 a706f9d5d11b6681ebf7f80368a2f281 65 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 17.494 T 22-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17860 a706f9d5d11b6681ebf7f80368a2f281 65 SUPERFAMILY SSF46561 1 63 3.92E-22 T 22-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17860 a706f9d5d11b6681ebf7f80368a2f281 65 PANTHER PTHR10916 1 59 2.5E-23 T 22-04-2016 HRM2_RS17860 a706f9d5d11b6681ebf7f80368a2f281 65 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 59 3.2E-20 T 22-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17860 a706f9d5d11b6681ebf7f80368a2f281 65 PANTHER PTHR10916:SF0 1 59 2.5E-23 T 22-04-2016 HRM2_RS17860 a706f9d5d11b6681ebf7f80368a2f281 65 Pfam PF00831 Ribosomal L29 protein 4 59 9.8E-23 T 22-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS21775 4a2f469313ce9d34d4697cbc40a58081 308 Gene3D G3DSA:1.10.3720.10 96 301 9.1E-24 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS21775 4a2f469313ce9d34d4697cbc40a58081 308 PANTHER PTHR30465 20 305 2.7E-107 T 22-04-2016 HRM2_RS21775 4a2f469313ce9d34d4697cbc40a58081 308 PANTHER PTHR30465:SF10 20 305 2.7E-107 T 22-04-2016 HRM2_RS21775 4a2f469313ce9d34d4697cbc40a58081 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 302 3.0E-29 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS21775 4a2f469313ce9d34d4697cbc40a58081 308 SUPERFAMILY SSF161098 106 285 1.96E-24 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS21775 4a2f469313ce9d34d4697cbc40a58081 308 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 28 80 1.7E-11 T 22-04-2016 IPR025966 Oligopeptide transport permease C-like, N-terminal domain HRM2_RS16470 a78687dd9bfe47d61d7147eef7eec6c7 593 SUPERFAMILY SSF90123 19 340 1.57E-76 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HRM2_RS16470 a78687dd9bfe47d61d7147eef7eec6c7 593 Gene3D G3DSA:1.20.1560.10 20 340 9.9E-79 T 22-04-2016 HRM2_RS16470 a78687dd9bfe47d61d7147eef7eec6c7 593 Gene3D G3DSA:3.40.50.300 355 587 8.7E-65 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16470 a78687dd9bfe47d61d7147eef7eec6c7 593 Pfam PF00664 ABC transporter transmembrane region 33 312 1.6E-49 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HRM2_RS16470 a78687dd9bfe47d61d7147eef7eec6c7 593 PANTHER PTHR24221 6 593 7.0E-164 T 22-04-2016 HRM2_RS16470 a78687dd9bfe47d61d7147eef7eec6c7 593 Pfam PF00005 ABC transporter 371 519 4.8E-28 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS16470 a78687dd9bfe47d61d7147eef7eec6c7 593 SMART SM00382 380 566 2.5E-15 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS16470 a78687dd9bfe47d61d7147eef7eec6c7 593 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS16470 a78687dd9bfe47d61d7147eef7eec6c7 593 SUPERFAMILY SSF52540 353 589 1.33E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23410 6fd75b9333e0dd05763d882cec9f4fb8 356 Pfam PF01032 FecCD transport family 30 352 3.2E-87 T 22-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 HRM2_RS23410 6fd75b9333e0dd05763d882cec9f4fb8 356 PANTHER PTHR30472:SF25 8 356 1.7E-143 T 22-04-2016 HRM2_RS23410 6fd75b9333e0dd05763d882cec9f4fb8 356 SUPERFAMILY SSF81345 14 352 2.22E-79 T 22-04-2016 IPR029022 ABC transporter, BtuC-like HRM2_RS23410 6fd75b9333e0dd05763d882cec9f4fb8 356 Gene3D G3DSA:1.10.3470.10 20 355 6.8E-101 T 22-04-2016 IPR029022 ABC transporter, BtuC-like HRM2_RS23410 6fd75b9333e0dd05763d882cec9f4fb8 356 PANTHER PTHR30472 8 356 1.7E-143 T 22-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 HRM2_RS21465 3f540e6ac9ae9c46d9404b2fdcc0d398 114 PANTHER PTHR33495:SF3 1 114 2.0E-30 T 22-04-2016 HRM2_RS21465 3f540e6ac9ae9c46d9404b2fdcc0d398 114 Pfam PF01740 STAS domain 7 106 5.2E-15 T 22-04-2016 IPR002645 STAS domain HRM2_RS21465 3f540e6ac9ae9c46d9404b2fdcc0d398 114 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 104 5.0E-21 T 22-04-2016 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 HRM2_RS21465 3f540e6ac9ae9c46d9404b2fdcc0d398 114 PANTHER PTHR33495 1 114 2.0E-30 T 22-04-2016 HRM2_RS21465 3f540e6ac9ae9c46d9404b2fdcc0d398 114 Gene3D G3DSA:3.30.750.24 1 111 2.7E-32 T 22-04-2016 IPR002645 STAS domain HRM2_RS21465 3f540e6ac9ae9c46d9404b2fdcc0d398 114 SUPERFAMILY SSF52091 1 108 1.18E-25 T 22-04-2016 IPR002645 STAS domain HRM2_RS19425 6d0d8a3c28458658fbff06150b77492c 137 SMART SM00267 1 129 8.6E-20 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS19425 6d0d8a3c28458658fbff06150b77492c 137 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 1 128 2.9E-42 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS19425 6d0d8a3c28458658fbff06150b77492c 137 Pfam PF00990 Diguanylate cyclase, GGDEF domain 1 125 8.8E-39 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS19425 6d0d8a3c28458658fbff06150b77492c 137 PANTHER PTHR10799:SF750 1 125 1.4E-27 T 22-04-2016 HRM2_RS19425 6d0d8a3c28458658fbff06150b77492c 137 Gene3D G3DSA:3.30.70.270 1 130 1.2E-40 T 22-04-2016 HRM2_RS19425 6d0d8a3c28458658fbff06150b77492c 137 PANTHER PTHR10799 1 125 1.4E-27 T 22-04-2016 HRM2_RS19425 6d0d8a3c28458658fbff06150b77492c 137 SUPERFAMILY SSF55073 1 130 1.73E-39 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS23645 57b893968c42805d5341b8d201597028 959 SUPERFAMILY SSF81593 298 447 2.35E-37 T 22-04-2016 HRM2_RS23645 57b893968c42805d5341b8d201597028 959 SUPERFAMILY SSF81593 832 958 2.43E-29 T 22-04-2016 HRM2_RS23645 57b893968c42805d5341b8d201597028 959 Hamap MF_00802 Glutamate-ammonia-ligase adenylyltransferase [glnE]. 37 956 17.724 T 22-04-2016 IPR023057 Glutamate-ammonia-ligase adenylyltransferase GO:0008882 HRM2_RS23645 57b893968c42805d5341b8d201597028 959 PANTHER PTHR30621 14 954 3.7E-284 T 22-04-2016 HRM2_RS23645 57b893968c42805d5341b8d201597028 959 SUPERFAMILY SSF81301 540 830 4.58E-74 T 22-04-2016 HRM2_RS23645 57b893968c42805d5341b8d201597028 959 SUPERFAMILY SSF81301 40 297 4.25E-74 T 22-04-2016 HRM2_RS23645 57b893968c42805d5341b8d201597028 959 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 568 822 1.7E-72 T 22-04-2016 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 HRM2_RS23645 57b893968c42805d5341b8d201597028 959 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 42 287 1.0E-72 T 22-04-2016 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 HRM2_RS23645 57b893968c42805d5341b8d201597028 959 Gene3D G3DSA:3.30.460.10 654 828 2.4E-55 T 22-04-2016 HRM2_RS23645 57b893968c42805d5341b8d201597028 959 Gene3D G3DSA:3.30.460.10 124 296 3.8E-57 T 22-04-2016 HRM2_RS23645 57b893968c42805d5341b8d201597028 959 Pfam PF08335 GlnD PII-uridylyltransferase 839 937 4.9E-12 T 22-04-2016 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 HRM2_RS23645 57b893968c42805d5341b8d201597028 959 Pfam PF08335 GlnD PII-uridylyltransferase 308 446 1.8E-39 T 22-04-2016 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 HRM2_RS15950 8a2519cf697aabe0126401baa26e1058 186 PANTHER PTHR37478 1 96 1.4E-21 T 22-04-2016 HRM2_RS15950 8a2519cf697aabe0126401baa26e1058 186 Pfam PF02001 Protein of unknown function DUF134 3 94 3.3E-23 T 22-04-2016 IPR002852 Uncharacterised protein family UPF0251 HRM2_RS15950 8a2519cf697aabe0126401baa26e1058 186 Hamap MF_00674 UPF0251 protein . 2 96 20.141 T 22-04-2016 IPR002852 Uncharacterised protein family UPF0251 HRM2_RS15950 8a2519cf697aabe0126401baa26e1058 186 Gene3D G3DSA:1.10.10.10 32 79 1.3E-4 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS15950 8a2519cf697aabe0126401baa26e1058 186 SUPERFAMILY SSF88659 32 78 2.03E-5 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS15950 8a2519cf697aabe0126401baa26e1058 186 PANTHER PTHR37478:SF1 1 96 1.4E-21 T 22-04-2016 HRM2_RS16540 4265336eb1a28c9952753aa4bdc6d54f 641 Gene3D G3DSA:3.40.50.970 384 559 1.5E-13 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS16540 4265336eb1a28c9952753aa4bdc6d54f 641 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 24 228 5.7E-12 T 22-04-2016 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 HRM2_RS16540 4265336eb1a28c9952753aa4bdc6d54f 641 Gene3D G3DSA:3.30.70.20 560 638 6.5E-8 T 22-04-2016 HRM2_RS16540 4265336eb1a28c9952753aa4bdc6d54f 641 SUPERFAMILY SSF54862 565 638 2.83E-7 T 22-04-2016 HRM2_RS16540 4265336eb1a28c9952753aa4bdc6d54f 641 PANTHER PTHR18968:SF91 365 641 1.7E-47 T 22-04-2016 HRM2_RS16540 4265336eb1a28c9952753aa4bdc6d54f 641 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 412 550 2.4E-21 T 22-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HRM2_RS16540 4265336eb1a28c9952753aa4bdc6d54f 641 SUPERFAMILY SSF52518 10 214 3.39E-51 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS16540 4265336eb1a28c9952753aa4bdc6d54f 641 PIRSF PIRSF006439 1 641 7.5E-179 T 22-04-2016 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 HRM2_RS16540 4265336eb1a28c9952753aa4bdc6d54f 641 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 620 631 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS16540 4265336eb1a28c9952753aa4bdc6d54f 641 PANTHER PTHR18968 365 641 1.7E-47 T 22-04-2016 HRM2_RS16540 4265336eb1a28c9952753aa4bdc6d54f 641 SUPERFAMILY SSF52518 377 563 2.38E-23 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS16540 4265336eb1a28c9952753aa4bdc6d54f 641 Pfam PF00037 4Fe-4S binding domain 615 636 1.1E-4 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS16540 4265336eb1a28c9952753aa4bdc6d54f 641 Gene3D G3DSA:3.40.50.920 239 330 1.2E-5 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HRM2_RS16540 4265336eb1a28c9952753aa4bdc6d54f 641 SUPERFAMILY SSF52922 243 311 4.71E-7 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HRM2_RS16540 4265336eb1a28c9952753aa4bdc6d54f 641 Gene3D G3DSA:3.40.50.970 5 187 6.8E-52 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS14360 a58194a20ef60a8541a9a5447cc81d78 637 PANTHER PTHR33362 11 634 8.1E-161 T 22-04-2016 HRM2_RS14360 a58194a20ef60a8541a9a5447cc81d78 637 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 12 616 2.1E-173 T 22-04-2016 IPR011853 TRAP transporter, 4TM/12TM fusion protein HRM2_RS14360 a58194a20ef60a8541a9a5447cc81d78 637 PANTHER PTHR33362:SF1 11 634 8.1E-161 T 22-04-2016 HRM2_RS14360 a58194a20ef60a8541a9a5447cc81d78 637 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 109 544 9.1E-83 T 22-04-2016 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit HRM2_RS08265 4be7217461293fcbf8d734efd3d2845d 301 SUPERFAMILY SSF51717 12 264 6.8E-56 T 22-04-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 HRM2_RS08265 4be7217461293fcbf8d734efd3d2845d 301 Pfam PF00809 Pterin binding enzyme 11 237 2.3E-16 T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 HRM2_RS08265 4be7217461293fcbf8d734efd3d2845d 301 Gene3D G3DSA:3.20.20.20 2 245 5.2E-67 T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 HRM2_RS08265 4be7217461293fcbf8d734efd3d2845d 301 Gene3D G3DSA:3.20.20.20 278 300 5.2E-67 T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 HRM2_RS24660 e130f6d7f63c699dc2245dca963c428b 190 PANTHER PTHR30006 9 162 4.2E-54 T 22-04-2016 HRM2_RS24660 e130f6d7f63c699dc2245dca963c428b 190 PANTHER PTHR30006 179 190 4.2E-54 T 22-04-2016 HRM2_RS24660 e130f6d7f63c699dc2245dca963c428b 190 Pfam PF13416 Bacterial extracellular solute-binding protein 11 188 1.2E-12 T 22-04-2016 HRM2_RS24660 e130f6d7f63c699dc2245dca963c428b 190 SUPERFAMILY SSF53850 7 163 3.8E-12 T 22-04-2016 HRM2_RS24660 e130f6d7f63c699dc2245dca963c428b 190 PANTHER PTHR30006:SF12 9 162 4.2E-54 T 22-04-2016 HRM2_RS24660 e130f6d7f63c699dc2245dca963c428b 190 PANTHER PTHR30006:SF12 179 190 4.2E-54 T 22-04-2016 HRM2_RS24660 e130f6d7f63c699dc2245dca963c428b 190 Gene3D G3DSA:3.40.190.10 6 108 1.2E-8 T 22-04-2016 HRM2_RS22420 4d271c1a5046fd39f09d75b7bf37bbf5 533 PANTHER PTHR30290:SF14 1 533 1.5E-209 T 22-04-2016 HRM2_RS22420 4d271c1a5046fd39f09d75b7bf37bbf5 533 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 71 451 1.7E-105 T 22-04-2016 IPR000914 Solute-binding protein family 5 domain HRM2_RS22420 4d271c1a5046fd39f09d75b7bf37bbf5 533 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 76 98 - T 22-04-2016 IPR023765 Solute-binding protein family 5, conserved site HRM2_RS22420 4d271c1a5046fd39f09d75b7bf37bbf5 533 PANTHER PTHR30290 1 533 1.5E-209 T 22-04-2016 HRM2_RS22420 4d271c1a5046fd39f09d75b7bf37bbf5 533 Gene3D G3DSA:3.10.105.10 286 502 2.8E-66 T 22-04-2016 HRM2_RS22420 4d271c1a5046fd39f09d75b7bf37bbf5 533 PIRSF PIRSF002741 20 531 2.5E-115 T 22-04-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 HRM2_RS22420 4d271c1a5046fd39f09d75b7bf37bbf5 533 SUPERFAMILY SSF53850 26 530 1.07E-155 T 22-04-2016 HRM2_RS22420 4d271c1a5046fd39f09d75b7bf37bbf5 533 Gene3D G3DSA:3.90.76.10 36 216 1.9E-48 T 22-04-2016 HRM2_RS05705 bc0afd87d548408ee28f40edc77a64b4 434 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 11 87 2.8E-23 T 22-04-2016 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: REACT_15518|Reactome: REACT_1698 HRM2_RS05705 bc0afd87d548408ee28f40edc77a64b4 434 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 209 425 1.4E-59 T 22-04-2016 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: REACT_15518|Reactome: REACT_1698 HRM2_RS05705 bc0afd87d548408ee28f40edc77a64b4 434 PANTHER PTHR10590 7 428 2.7E-131 T 22-04-2016 IPR008276 Concentrative nucleoside transporter GO:0005337|GO:0016020|GO:1901642 Reactome: REACT_15518|Reactome: REACT_1698 HRM2_RS18110 8e35f8bccfa2d03d5619aee3ad5232ed 272 Gene3D G3DSA:3.30.1330.60 135 252 1.3E-28 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS18110 8e35f8bccfa2d03d5619aee3ad5232ed 272 PANTHER PTHR30329:SF4 135 272 8.7E-35 T 22-04-2016 HRM2_RS18110 8e35f8bccfa2d03d5619aee3ad5232ed 272 Pfam PF00691 OmpA family 147 246 3.1E-18 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS18110 8e35f8bccfa2d03d5619aee3ad5232ed 272 PANTHER PTHR30329 135 272 8.7E-35 T 22-04-2016 HRM2_RS18110 8e35f8bccfa2d03d5619aee3ad5232ed 272 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 49 73 5.1E-6 T 22-04-2016 IPR025713 Motility protein B, N-terminal domain HRM2_RS18110 8e35f8bccfa2d03d5619aee3ad5232ed 272 SUPERFAMILY SSF103088 136 252 2.88E-28 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS25555 b710e22ea68b29e7f4b5a185bae1b10c 219 Gene3D G3DSA:1.10.287.130 18 80 4.7E-4 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS18310 135cc9ce3650a333424edaba60084831 368 SMART SM00382 172 358 5.0E-5 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS18310 135cc9ce3650a333424edaba60084831 368 PANTHER PTHR11564:SF3 154 367 2.9E-63 T 22-04-2016 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 HRM2_RS18310 135cc9ce3650a333424edaba60084831 368 SMART SM00962 173 364 4.2E-45 T 22-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 HRM2_RS18310 135cc9ce3650a333424edaba60084831 368 Gene3D G3DSA:1.20.120.140 110 185 1.8E-5 T 22-04-2016 HRM2_RS18310 135cc9ce3650a333424edaba60084831 368 SUPERFAMILY SSF52540 171 364 6.67E-31 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18310 135cc9ce3650a333424edaba60084831 368 PANTHER PTHR11564 154 367 2.9E-63 T 22-04-2016 HRM2_RS18310 135cc9ce3650a333424edaba60084831 368 Gene3D G3DSA:3.40.50.300 186 364 1.0E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18310 135cc9ce3650a333424edaba60084831 368 Pfam PF00448 SRP54-type protein, GTPase domain 175 363 4.7E-40 T 22-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 HRM2_RS22960 e5c2fba4b00ef776fe3152ffe561f66f 431 SUPERFAMILY SSF111352 27 408 4.32E-126 T 22-04-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 HRM2_RS22960 e5c2fba4b00ef776fe3152ffe561f66f 431 ProSitePatterns PS01219 Ammonium transporters signature. 183 208 - T 22-04-2016 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 HRM2_RS22960 e5c2fba4b00ef776fe3152ffe561f66f 431 PANTHER PTHR11730 3 429 4.7E-177 T 22-04-2016 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 HRM2_RS22960 e5c2fba4b00ef776fe3152ffe561f66f 431 TIGRFAM TIGR00836 amt: ammonium transporter 31 427 5.1E-135 T 22-04-2016 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 HRM2_RS22960 e5c2fba4b00ef776fe3152ffe561f66f 431 Pfam PF00909 Ammonium Transporter Family 33 427 5.8E-122 T 22-04-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 HRM2_RS22960 e5c2fba4b00ef776fe3152ffe561f66f 431 PANTHER PTHR11730:SF17 3 429 4.7E-177 T 22-04-2016 HRM2_RS22960 e5c2fba4b00ef776fe3152ffe561f66f 431 Gene3D G3DSA:1.10.3430.10 26 408 6.0E-137 T 22-04-2016 IPR029020 Ammonium/urea transporter HRM2_RS05960 21171f876a419a4b4b59830206496f44 163 Pfam PF13404 AsnC-type helix-turn-helix domain 6 46 1.4E-11 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 HRM2_RS05960 21171f876a419a4b4b59830206496f44 163 PANTHER PTHR30154 1 152 8.9E-25 T 22-04-2016 HRM2_RS05960 21171f876a419a4b4b59830206496f44 163 Gene3D G3DSA:3.30.70.920 68 143 2.4E-11 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain HRM2_RS05960 21171f876a419a4b4b59830206496f44 163 SMART SM00344 6 112 1.5E-20 T 22-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 HRM2_RS05960 21171f876a419a4b4b59830206496f44 163 Pfam PF01037 Lrp/AsnC ligand binding domain 73 143 4.8E-7 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain HRM2_RS05960 21171f876a419a4b4b59830206496f44 163 Gene3D G3DSA:1.10.10.10 2 53 9.3E-16 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS05960 21171f876a419a4b4b59830206496f44 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 3.4E-9 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 HRM2_RS05960 21171f876a419a4b4b59830206496f44 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 3.4E-9 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 HRM2_RS05960 21171f876a419a4b4b59830206496f44 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 3.4E-9 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 HRM2_RS05960 21171f876a419a4b4b59830206496f44 163 SUPERFAMILY SSF46785 6 55 8.51E-11 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS05960 21171f876a419a4b4b59830206496f44 163 SUPERFAMILY SSF54909 67 152 9.65E-11 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel HRM2_RS16890 383328a3bbe91445c1e89b6d40bb9fe5 251 Pfam PF00535 Glycosyl transferase family 2 7 165 5.6E-29 T 22-04-2016 IPR001173 Glycosyltransferase 2-like HRM2_RS16890 383328a3bbe91445c1e89b6d40bb9fe5 251 PANTHER PTHR10859 5 231 4.8E-72 T 22-04-2016 HRM2_RS16890 383328a3bbe91445c1e89b6d40bb9fe5 251 PANTHER PTHR10859:SF49 5 231 4.8E-72 T 22-04-2016 HRM2_RS16890 383328a3bbe91445c1e89b6d40bb9fe5 251 Gene3D G3DSA:3.90.550.10 2 178 7.8E-30 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS16890 383328a3bbe91445c1e89b6d40bb9fe5 251 SUPERFAMILY SSF53448 3 237 8.04E-44 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS14435 6187061ab364fcf07eba51491a6acdb7 270 PRINTS PR00344 Bacterial sensor protein C-terminal signature 231 249 1.7E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS14435 6187061ab364fcf07eba51491a6acdb7 270 PRINTS PR00344 Bacterial sensor protein C-terminal signature 218 228 1.7E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS14435 6187061ab364fcf07eba51491a6acdb7 270 PRINTS PR00344 Bacterial sensor protein C-terminal signature 255 268 1.7E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS14435 6187061ab364fcf07eba51491a6acdb7 270 PRINTS PR00344 Bacterial sensor protein C-terminal signature 200 214 1.7E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS14435 6187061ab364fcf07eba51491a6acdb7 270 SUPERFAMILY SSF47384 37 104 9.22E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS14435 6187061ab364fcf07eba51491a6acdb7 270 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 149 268 8.0E-22 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS14435 6187061ab364fcf07eba51491a6acdb7 270 SMART SM00388 42 108 0.0084 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS14435 6187061ab364fcf07eba51491a6acdb7 270 PANTHER PTHR24423:SF544 26 268 2.5E-70 T 22-04-2016 HRM2_RS14435 6187061ab364fcf07eba51491a6acdb7 270 Gene3D G3DSA:3.30.565.10 113 269 9.2E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS14435 6187061ab364fcf07eba51491a6acdb7 270 SUPERFAMILY SSF55874 98 269 1.83E-37 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS14435 6187061ab364fcf07eba51491a6acdb7 270 PANTHER PTHR24423 26 268 2.5E-70 T 22-04-2016 HRM2_RS14435 6187061ab364fcf07eba51491a6acdb7 270 SMART SM00387 148 270 4.2E-26 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS16825 3d88a86985fddae8763797b23a568ccb 1025 SUPERFAMILY SSF52540 271 408 2.41E-9 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16825 3d88a86985fddae8763797b23a568ccb 1025 SUPERFAMILY SSF56436 714 891 1.46E-44 T 22-04-2016 IPR016187 C-type lectin fold HRM2_RS16825 3d88a86985fddae8763797b23a568ccb 1025 Gene3D G3DSA:3.40.50.300 274 408 2.6E-5 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16825 3d88a86985fddae8763797b23a568ccb 1025 Pfam PF13271 Domain of unknown function (DUF4062) 10 101 3.3E-10 T 22-04-2016 IPR025139 Domain of unknown function DUF4062 HRM2_RS16825 3d88a86985fddae8763797b23a568ccb 1025 Gene3D G3DSA:3.90.1580.10 982 993 8.0E-43 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme HRM2_RS16825 3d88a86985fddae8763797b23a568ccb 1025 Gene3D G3DSA:3.90.1580.10 715 902 8.0E-43 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme HRM2_RS16825 3d88a86985fddae8763797b23a568ccb 1025 PANTHER PTHR23150 734 889 1.1E-40 T 22-04-2016 HRM2_RS16825 3d88a86985fddae8763797b23a568ccb 1025 Pfam PF05729 NACHT domain 277 441 6.1E-7 T 22-04-2016 HRM2_RS16825 3d88a86985fddae8763797b23a568ccb 1025 SMART SM00382 274 428 0.0011 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS16825 3d88a86985fddae8763797b23a568ccb 1025 Pfam PF03781 Sulfatase-modifying factor enzyme 1 729 893 5.3E-35 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme HRM2_RS14885 3fec0005f61d82af17ca0d726ae7069d 189 Pfam PF10741 Type II secretion system (T2SS), protein M subtype b 75 161 5.4E-7 T 22-04-2016 IPR007690 Type II secretion system, protein M GO:0006858 HRM2_RS16775 3ce366af0e4112373739af4764a507ec 98 SUPERFAMILY SSF55447 33 96 1.57E-12 T 22-04-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal HRM2_RS16775 3ce366af0e4112373739af4764a507ec 98 Gene3D G3DSA:3.30.390.50 36 90 4.3E-14 T 22-04-2016 HRM2_RS16775 3ce366af0e4112373739af4764a507ec 98 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 35 90 6.6E-12 T 22-04-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal HRM2_RS16775 3ce366af0e4112373739af4764a507ec 98 SMART SM01092 17 94 0.004 T 22-04-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal HRM2_RS06940 2ddc61c64d92ec2206bfc8b08ae7864c 323 PANTHER PTHR35038:SF3 30 312 4.4E-52 T 22-04-2016 HRM2_RS06940 2ddc61c64d92ec2206bfc8b08ae7864c 323 Pfam PF09699 Doubled CXXCH motif (Paired_CXXCH_1) 176 218 1.5E-10 T 22-04-2016 IPR010177 Doubled CXXCH motif UniPathway: UPA00045 HRM2_RS06940 2ddc61c64d92ec2206bfc8b08ae7864c 323 Pfam PF09699 Doubled CXXCH motif (Paired_CXXCH_1) 225 260 1.1E-8 T 22-04-2016 IPR010177 Doubled CXXCH motif UniPathway: UPA00045 HRM2_RS06940 2ddc61c64d92ec2206bfc8b08ae7864c 323 Pfam PF09699 Doubled CXXCH motif (Paired_CXXCH_1) 137 166 2.0E-7 T 22-04-2016 IPR010177 Doubled CXXCH motif UniPathway: UPA00045 HRM2_RS06940 2ddc61c64d92ec2206bfc8b08ae7864c 323 Pfam PF09699 Doubled CXXCH motif (Paired_CXXCH_1) 75 120 1.3E-4 T 22-04-2016 IPR010177 Doubled CXXCH motif UniPathway: UPA00045 HRM2_RS06940 2ddc61c64d92ec2206bfc8b08ae7864c 323 TIGRFAM TIGR03508 decahem_SO: decaheme c-type cytochrome, DmsE family 45 310 2.9E-73 T 22-04-2016 IPR020015 Decaheme cytochrome, c-type, DmsE HRM2_RS06940 2ddc61c64d92ec2206bfc8b08ae7864c 323 Gene3D G3DSA:1.10.780.10 40 305 1.1E-28 T 22-04-2016 HRM2_RS06940 2ddc61c64d92ec2206bfc8b08ae7864c 323 PANTHER PTHR35038 30 312 4.4E-52 T 22-04-2016 HRM2_RS06940 2ddc61c64d92ec2206bfc8b08ae7864c 323 TIGRFAM TIGR01905 paired_CXXCH_1: doubled CXXCH domain 225 260 2.5E-10 T 22-04-2016 IPR010177 Doubled CXXCH motif UniPathway: UPA00045 HRM2_RS06940 2ddc61c64d92ec2206bfc8b08ae7864c 323 TIGRFAM TIGR01905 paired_CXXCH_1: doubled CXXCH domain 176 217 2.4E-7 T 22-04-2016 IPR010177 Doubled CXXCH motif UniPathway: UPA00045 HRM2_RS06940 2ddc61c64d92ec2206bfc8b08ae7864c 323 TIGRFAM TIGR01905 paired_CXXCH_1: doubled CXXCH domain 135 166 2.6E-7 T 22-04-2016 IPR010177 Doubled CXXCH motif UniPathway: UPA00045 HRM2_RS06940 2ddc61c64d92ec2206bfc8b08ae7864c 323 SUPERFAMILY SSF48695 45 305 1.01E-38 T 22-04-2016 IPR011031 Multihaem cytochrome HRM2_RS08410 78119231386ed363363a4ef0fdf5e280 647 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 449 5.8E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS08410 78119231386ed363363a4ef0fdf5e280 647 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 463 5.8E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS08410 78119231386ed363363a4ef0fdf5e280 647 PRINTS PR00344 Bacterial sensor protein C-terminal signature 466 484 5.8E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS08410 78119231386ed363363a4ef0fdf5e280 647 PRINTS PR00344 Bacterial sensor protein C-terminal signature 490 503 5.8E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS08410 78119231386ed363363a4ef0fdf5e280 647 Gene3D G3DSA:3.40.50.2300 4 128 1.1E-38 T 22-04-2016 HRM2_RS08410 78119231386ed363363a4ef0fdf5e280 647 SMART SM00387 383 506 7.1E-26 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS08410 78119231386ed363363a4ef0fdf5e280 647 Gene3D G3DSA:3.40.50.2300 526 644 6.7E-30 T 22-04-2016 HRM2_RS08410 78119231386ed363363a4ef0fdf5e280 647 Gene3D G3DSA:3.30.450.20 129 260 5.5E-20 T 22-04-2016 HRM2_RS08410 78119231386ed363363a4ef0fdf5e280 647 Pfam PF00072 Response regulator receiver domain 6 115 2.3E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS08410 78119231386ed363363a4ef0fdf5e280 647 Pfam PF00072 Response regulator receiver domain 529 640 4.8E-23 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS08410 78119231386ed363363a4ef0fdf5e280 647 Pfam PF00989 PAS fold 144 259 1.7E-12 T 22-04-2016 IPR013767 PAS fold GO:0006355 HRM2_RS08410 78119231386ed363363a4ef0fdf5e280 647 SUPERFAMILY SSF52172 528 644 4.41E-29 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS08410 78119231386ed363363a4ef0fdf5e280 647 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 137 196 1.1E-9 T 22-04-2016 IPR000014 PAS domain HRM2_RS08410 78119231386ed363363a4ef0fdf5e280 647 PANTHER PTHR24423:SF544 123 644 2.7E-133 T 22-04-2016 HRM2_RS08410 78119231386ed363363a4ef0fdf5e280 647 SMART SM00091 140 206 4.3E-8 T 22-04-2016 IPR000014 PAS domain HRM2_RS08410 78119231386ed363363a4ef0fdf5e280 647 PANTHER PTHR24423 123 644 2.7E-133 T 22-04-2016 HRM2_RS08410 78119231386ed363363a4ef0fdf5e280 647 Gene3D G3DSA:3.30.565.10 348 505 6.2E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS08410 78119231386ed363363a4ef0fdf5e280 647 SUPERFAMILY SSF55785 127 260 8.9E-18 T 22-04-2016 IPR000014 PAS domain HRM2_RS08410 78119231386ed363363a4ef0fdf5e280 647 SMART SM00448 4 115 1.8E-36 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS08410 78119231386ed363363a4ef0fdf5e280 647 SMART SM00448 527 640 8.3E-23 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS08410 78119231386ed363363a4ef0fdf5e280 647 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 384 505 1.3E-16 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS08410 78119231386ed363363a4ef0fdf5e280 647 SUPERFAMILY SSF52172 4 159 6.4E-43 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS08410 78119231386ed363363a4ef0fdf5e280 647 SUPERFAMILY SSF47384 270 341 9.81E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS08410 78119231386ed363363a4ef0fdf5e280 647 SUPERFAMILY SSF55874 340 504 2.88E-34 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS13245 2bcbe5205e1a641ac8dc145d3aa7b328 227 SUPERFAMILY SSF52540 1 210 1.84E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13245 2bcbe5205e1a641ac8dc145d3aa7b328 227 Hamap MF_00165 Thymidylate kinase [tmk]. 1 209 30.287 T 22-04-2016 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 HRM2_RS13245 2bcbe5205e1a641ac8dc145d3aa7b328 227 PANTHER PTHR10344 1 209 4.8E-66 T 22-04-2016 HRM2_RS13245 2bcbe5205e1a641ac8dc145d3aa7b328 227 Pfam PF02223 Thymidylate kinase 5 201 1.1E-47 T 22-04-2016 HRM2_RS13245 2bcbe5205e1a641ac8dc145d3aa7b328 227 Gene3D G3DSA:3.40.50.300 1 209 2.9E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13245 2bcbe5205e1a641ac8dc145d3aa7b328 227 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 1 201 8.6E-52 T 22-04-2016 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 HRM2_RS23155 47cad3f948de2da9d30c40764d8f2f29 698 SUPERFAMILY SSF54292 66 162 8.89E-22 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 HRM2_RS23155 47cad3f948de2da9d30c40764d8f2f29 698 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 80 148 4.4E-13 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 HRM2_RS23155 47cad3f948de2da9d30c40764d8f2f29 698 Gene3D G3DSA:3.10.20.30 73 163 1.1E-20 T 22-04-2016 IPR012675 Beta-grasp domain HRM2_RS23155 47cad3f948de2da9d30c40764d8f2f29 698 SUPERFAMILY SSF53067 509 529 5.35E-6 T 22-04-2016 HRM2_RS23155 47cad3f948de2da9d30c40764d8f2f29 698 SUPERFAMILY SSF53067 276 375 5.35E-6 T 22-04-2016 HRM2_RS23155 47cad3f948de2da9d30c40764d8f2f29 698 SUPERFAMILY SSF53067 419 463 5.35E-6 T 22-04-2016 HRM2_RS23155 47cad3f948de2da9d30c40764d8f2f29 698 SUPERFAMILY SSF53067 561 610 5.35E-6 T 22-04-2016 HRM2_RS23155 47cad3f948de2da9d30c40764d8f2f29 698 Pfam PF14574 Domain of unknown function (DUF4445) 274 682 3.6E-133 T 22-04-2016 IPR027980 Protein of unknown function DUF4445 HRM2_RS08230 efcd6236e346932123af44978a5f9337 117 Gene3D G3DSA:3.40.1390.20 3 104 6.5E-13 T 22-04-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like HRM2_RS08230 efcd6236e346932123af44978a5f9337 117 Pfam PF07085 DRTGG domain 5 102 2.3E-7 T 22-04-2016 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 HRM2_RS08230 efcd6236e346932123af44978a5f9337 117 SUPERFAMILY SSF75138 3 108 1.05E-16 T 22-04-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like HRM2_RS00475 96e38764fb061233bce2f8325476d328 450 Pfam PF13414 TPR repeat 178 209 3.9E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS00475 96e38764fb061233bce2f8325476d328 450 SUPERFAMILY SSF53335 255 448 8.22E-28 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS00475 96e38764fb061233bce2f8325476d328 450 PANTHER PTHR23083 37 238 5.9E-45 T 22-04-2016 HRM2_RS00475 96e38764fb061233bce2f8325476d328 450 Gene3D G3DSA:1.25.40.10 26 238 2.1E-54 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS00475 96e38764fb061233bce2f8325476d328 450 Gene3D G3DSA:3.40.50.150 253 427 4.2E-24 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS00475 96e38764fb061233bce2f8325476d328 450 Pfam PF13424 Tetratricopeptide repeat 27 88 7.0E-8 T 22-04-2016 HRM2_RS00475 96e38764fb061233bce2f8325476d328 450 SUPERFAMILY SSF48452 26 228 1.59E-42 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS00475 96e38764fb061233bce2f8325476d328 450 Pfam PF00515 Tetratricopeptide repeat 128 158 1.0E-6 T 22-04-2016 IPR001440 Tetratricopeptide repeat 1 GO:0005515 HRM2_RS00475 96e38764fb061233bce2f8325476d328 450 SMART SM00028 195 228 2.1E-4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS00475 96e38764fb061233bce2f8325476d328 450 SMART SM00028 127 160 3.8E-5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS00475 96e38764fb061233bce2f8325476d328 450 SMART SM00028 25 58 210.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS00475 96e38764fb061233bce2f8325476d328 450 SMART SM00028 161 194 5.0E-5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS00475 96e38764fb061233bce2f8325476d328 450 SMART SM00028 59 92 0.035 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS00475 96e38764fb061233bce2f8325476d328 450 SMART SM00028 93 126 16.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS00475 96e38764fb061233bce2f8325476d328 450 Pfam PF13489 Methyltransferase domain 279 388 4.6E-13 T 22-04-2016 HRM2_RS13130 38bc631a9f59bd2072bed26f3ab6ebae 298 SUPERFAMILY SSF55120 77 290 6.72E-48 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS13130 38bc631a9f59bd2072bed26f3ab6ebae 298 PANTHER PTHR11079 60 293 3.1E-68 T 22-04-2016 HRM2_RS13130 38bc631a9f59bd2072bed26f3ab6ebae 298 PANTHER PTHR11079:SF61 60 293 3.1E-68 T 22-04-2016 HRM2_RS13130 38bc631a9f59bd2072bed26f3ab6ebae 298 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 131 145 - T 22-04-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS13130 38bc631a9f59bd2072bed26f3ab6ebae 298 Pfam PF00849 RNA pseudouridylate synthase 92 240 2.2E-22 T 22-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS04640 27ac852629fd2e8ea39b23b00c384e4a 342 SUPERFAMILY SSF140931 251 289 1.01E-6 T 22-04-2016 IPR003812 Fido domain HRM2_RS04640 27ac852629fd2e8ea39b23b00c384e4a 342 PANTHER PTHR35810 1 337 1.8E-94 T 22-04-2016 HRM2_RS04640 27ac852629fd2e8ea39b23b00c384e4a 342 PANTHER PTHR35810:SF2 1 337 1.8E-94 T 22-04-2016 HRM2_RS04640 27ac852629fd2e8ea39b23b00c384e4a 342 Gene3D G3DSA:1.10.3290.10 254 292 1.9E-4 T 22-04-2016 IPR003812 Fido domain HRM2_RS04640 27ac852629fd2e8ea39b23b00c384e4a 342 Pfam PF02661 Fic/DOC family 209 285 8.4E-9 T 22-04-2016 IPR003812 Fido domain HRM2_RS04640 27ac852629fd2e8ea39b23b00c384e4a 342 Pfam PF13310 Virulence protein RhuM family 64 137 5.4E-24 T 22-04-2016 IPR011204 Virulence protein RhuM-like HRM2_RS06190 7a7ab86541c4e5404edf044291aab1da 341 SUPERFAMILY SSF51395 36 332 1.28E-57 T 22-04-2016 HRM2_RS06190 7a7ab86541c4e5404edf044291aab1da 341 Gene3D G3DSA:3.20.20.70 5 337 7.5E-75 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS06190 7a7ab86541c4e5404edf044291aab1da 341 Pfam PF01070 FMN-dependent dehydrogenase 35 179 3.3E-12 T 22-04-2016 IPR000262 FMN-dependent dehydrogenase GO:0016491 HRM2_RS06190 7a7ab86541c4e5404edf044291aab1da 341 Pfam PF01070 FMN-dependent dehydrogenase 192 335 6.0E-53 T 22-04-2016 IPR000262 FMN-dependent dehydrogenase GO:0016491 HRM2_RS06190 7a7ab86541c4e5404edf044291aab1da 341 PANTHER PTHR10578:SF65 46 339 3.8E-56 T 22-04-2016 HRM2_RS06190 7a7ab86541c4e5404edf044291aab1da 341 PANTHER PTHR10578 46 339 3.8E-56 T 22-04-2016 HRM2_RS21290 5e1037866a54ae02fbb1e652ce4a2ffa 416 PANTHER PTHR22642:SF1 5 415 1.6E-148 T 22-04-2016 HRM2_RS21290 5e1037866a54ae02fbb1e652ce4a2ffa 416 PANTHER PTHR22642 5 415 1.6E-148 T 22-04-2016 HRM2_RS21290 5e1037866a54ae02fbb1e652ce4a2ffa 416 Gene3D G3DSA:3.20.20.140 83 358 9.3E-42 T 22-04-2016 HRM2_RS21290 5e1037866a54ae02fbb1e652ce4a2ffa 416 Pfam PF01979 Amidohydrolase family 73 412 2.6E-17 T 22-04-2016 IPR006680 Amidohydrolase-related GO:0016787 HRM2_RS21290 5e1037866a54ae02fbb1e652ce4a2ffa 416 TIGRFAM TIGR01224 hutI: imidazolonepropionase 33 411 4.7E-137 T 22-04-2016 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 HRM2_RS21290 5e1037866a54ae02fbb1e652ce4a2ffa 416 SUPERFAMILY SSF51556 75 373 7.21E-77 T 22-04-2016 IPR032466 Metal-dependent hydrolase HRM2_RS21290 5e1037866a54ae02fbb1e652ce4a2ffa 416 Gene3D G3DSA:2.30.40.10 5 82 1.7E-12 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS21290 5e1037866a54ae02fbb1e652ce4a2ffa 416 Hamap MF_00372 Imidazolonepropionase [hutI]. 4 412 42.204 T 22-04-2016 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 HRM2_RS21290 5e1037866a54ae02fbb1e652ce4a2ffa 416 Gene3D G3DSA:2.30.40.10 359 406 2.5E-8 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS21290 5e1037866a54ae02fbb1e652ce4a2ffa 416 SUPERFAMILY SSF51338 27 76 2.59E-17 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS21290 5e1037866a54ae02fbb1e652ce4a2ffa 416 SUPERFAMILY SSF51338 372 414 2.59E-17 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS19205 f9eab8a4d573acaa34141742fd6d6003 314 SUPERFAMILY SSF51726 91 299 5.89E-19 T 22-04-2016 HRM2_RS19205 f9eab8a4d573acaa34141742fd6d6003 314 Gene3D G3DSA:3.20.20.210 75 296 4.9E-18 T 22-04-2016 HRM2_RS19205 f9eab8a4d573acaa34141742fd6d6003 314 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 94 286 7.6E-11 T 22-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 HRM2_RS07985 09a9043da04846c1c125823013db802a 282 PANTHER PTHR23309 3 282 6.5E-146 T 22-04-2016 HRM2_RS07985 09a9043da04846c1c125823013db802a 282 Gene3D G3DSA:3.40.50.720 2 185 4.4E-64 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS07985 09a9043da04846c1c125823013db802a 282 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 181 205 - T 22-04-2016 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 HRM2_RS07985 09a9043da04846c1c125823013db802a 282 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3 181 1.5E-67 T 22-04-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 HRM2_RS07985 09a9043da04846c1c125823013db802a 282 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 184 280 2.5E-34 T 22-04-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 HRM2_RS07985 09a9043da04846c1c125823013db802a 282 Gene3D G3DSA:1.10.1040.10 186 280 9.3E-37 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HRM2_RS07985 09a9043da04846c1c125823013db802a 282 PIRSF PIRSF000105 1 282 1.0E-90 T 22-04-2016 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 HRM2_RS07985 09a9043da04846c1c125823013db802a 282 SUPERFAMILY SSF48179 183 281 1.28E-32 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HRM2_RS07985 09a9043da04846c1c125823013db802a 282 SUPERFAMILY SSF51735 1 181 5.67E-60 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS02645 ed8fe0ff1f5886cd7e42bac97c3a4f71 815 Hamap MF_00983 Probable primosomal protein N' [priA]. 9 814 24.567 T 22-04-2016 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 HRM2_RS02645 ed8fe0ff1f5886cd7e42bac97c3a4f71 815 SUPERFAMILY SSF52540 270 443 9.58E-39 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02645 ed8fe0ff1f5886cd7e42bac97c3a4f71 815 PANTHER PTHR30580 1 815 5.4E-245 T 22-04-2016 HRM2_RS02645 ed8fe0ff1f5886cd7e42bac97c3a4f71 815 Gene3D G3DSA:3.40.50.300 568 711 9.8E-25 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02645 ed8fe0ff1f5886cd7e42bac97c3a4f71 815 Gene3D G3DSA:3.40.50.300 486 507 9.8E-25 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02645 ed8fe0ff1f5886cd7e42bac97c3a4f71 815 SMART SM00487 269 467 4.7E-22 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS02645 ed8fe0ff1f5886cd7e42bac97c3a4f71 815 Pfam PF00271 Helicase conserved C-terminal domain 581 667 8.2E-5 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS02645 ed8fe0ff1f5886cd7e42bac97c3a4f71 815 SUPERFAMILY SSF52540 539 721 1.51E-23 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02645 ed8fe0ff1f5886cd7e42bac97c3a4f71 815 Gene3D G3DSA:3.40.50.300 265 443 1.9E-36 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02645 ed8fe0ff1f5886cd7e42bac97c3a4f71 815 Pfam PF04851 Type III restriction enzyme, res subunit 273 435 9.0E-15 T 22-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HRM2_RS02645 ed8fe0ff1f5886cd7e42bac97c3a4f71 815 SMART SM00490 571 668 7.3E-6 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS02645 ed8fe0ff1f5886cd7e42bac97c3a4f71 815 TIGRFAM TIGR00595 priA: primosomal protein N' 296 812 1.1E-184 T 22-04-2016 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 HRM2_RS11725 33c7ed7511ebb69e1a0dde95d397265d 851 PIRSF PIRSF000460 1 794 1.1E-240 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HRM2_RS11725 33c7ed7511ebb69e1a0dde95d397265d 851 Gene3D G3DSA:3.40.50.2000 417 712 2.8E-80 T 22-04-2016 HRM2_RS11725 33c7ed7511ebb69e1a0dde95d397265d 851 Pfam PF00343 Carbohydrate phosphorylase 270 621 6.4E-21 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HRM2_RS11725 33c7ed7511ebb69e1a0dde95d397265d 851 Pfam PF00343 Carbohydrate phosphorylase 124 170 2.8E-4 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HRM2_RS11725 33c7ed7511ebb69e1a0dde95d397265d 851 Pfam PF11897 Protein of unknown function (DUF3417) 13 120 7.6E-31 T 22-04-2016 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 HRM2_RS11725 33c7ed7511ebb69e1a0dde95d397265d 851 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 107 709 4.2E-242 T 22-04-2016 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 HRM2_RS11725 33c7ed7511ebb69e1a0dde95d397265d 851 PANTHER PTHR11468 107 476 4.7E-228 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HRM2_RS11725 33c7ed7511ebb69e1a0dde95d397265d 851 PANTHER PTHR11468 494 776 4.7E-228 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HRM2_RS11725 33c7ed7511ebb69e1a0dde95d397265d 851 PANTHER PTHR11468:SF9 107 476 4.7E-228 T 22-04-2016 HRM2_RS11725 33c7ed7511ebb69e1a0dde95d397265d 851 PANTHER PTHR11468:SF9 494 776 4.7E-228 T 22-04-2016 HRM2_RS11725 33c7ed7511ebb69e1a0dde95d397265d 851 SUPERFAMILY SSF53756 23 715 9.81E-191 T 22-04-2016 HRM2_RS11725 33c7ed7511ebb69e1a0dde95d397265d 851 Gene3D G3DSA:3.40.50.2000 25 416 1.4E-64 T 22-04-2016 HRM2_RS20945 0248663a79bc1e1997a9c333172f30af 273 Gene3D G3DSA:3.40.50.300 34 225 8.1E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20945 0248663a79bc1e1997a9c333172f30af 273 SUPERFAMILY SSF52540 32 198 3.47E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18625 3f65247b90fc8ad8107ff280abca33cd 252 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 39 246 3.9E-36 T 22-04-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HRM2_RS18625 3f65247b90fc8ad8107ff280abca33cd 252 PANTHER PTHR32089 1 250 7.0E-57 T 22-04-2016 HRM2_RS18625 3f65247b90fc8ad8107ff280abca33cd 252 SUPERFAMILY SSF58104 2 227 2.09E-51 T 22-04-2016 HRM2_RS18625 3f65247b90fc8ad8107ff280abca33cd 252 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 154 183 1.3E-6 T 22-04-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HRM2_RS18625 3f65247b90fc8ad8107ff280abca33cd 252 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 7 36 1.3E-6 T 22-04-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HRM2_RS18625 3f65247b90fc8ad8107ff280abca33cd 252 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 106 135 1.3E-6 T 22-04-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HRM2_RS18625 3f65247b90fc8ad8107ff280abca33cd 252 Gene3D G3DSA:1.10.287.950 2 202 4.2E-46 T 22-04-2016 HRM2_RS18625 3f65247b90fc8ad8107ff280abca33cd 252 SMART SM00283 1 247 1.7E-33 T 22-04-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HRM2_RS19105 7bb25936cd5ab863032c4a909a66994b 440 PIRSF PIRSF006066 5 440 2.8E-86 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS19105 7bb25936cd5ab863032c4a909a66994b 440 PANTHER PTHR33362 8 437 8.7E-105 T 22-04-2016 HRM2_RS19105 7bb25936cd5ab863032c4a909a66994b 440 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 23 435 3.7E-100 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS19105 7bb25936cd5ab863032c4a909a66994b 440 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 11 430 3.7E-90 T 22-04-2016 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit HRM2_RS19105 7bb25936cd5ab863032c4a909a66994b 440 PANTHER PTHR33362:SF7 8 437 8.7E-105 T 22-04-2016 HRM2_RS12395 f80f5a4b6c1e439f25538c8ed7e4708f 471 PRINTS PR01050 Pyruvate kinase family signature 238 262 8.8E-67 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS12395 f80f5a4b6c1e439f25538c8ed7e4708f 471 PRINTS PR01050 Pyruvate kinase family signature 288 306 8.8E-67 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS12395 f80f5a4b6c1e439f25538c8ed7e4708f 471 PRINTS PR01050 Pyruvate kinase family signature 181 195 8.8E-67 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS12395 f80f5a4b6c1e439f25538c8ed7e4708f 471 PRINTS PR01050 Pyruvate kinase family signature 263 287 8.8E-67 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS12395 f80f5a4b6c1e439f25538c8ed7e4708f 471 PRINTS PR01050 Pyruvate kinase family signature 211 237 8.8E-67 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS12395 f80f5a4b6c1e439f25538c8ed7e4708f 471 PRINTS PR01050 Pyruvate kinase family signature 56 72 8.8E-67 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS12395 f80f5a4b6c1e439f25538c8ed7e4708f 471 PRINTS PR01050 Pyruvate kinase family signature 307 323 8.8E-67 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS12395 f80f5a4b6c1e439f25538c8ed7e4708f 471 SUPERFAMILY SSF52935 318 460 8.9E-23 T 22-04-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS12395 f80f5a4b6c1e439f25538c8ed7e4708f 471 Gene3D G3DSA:2.40.33.10 70 163 4.6E-21 T 22-04-2016 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS12395 f80f5a4b6c1e439f25538c8ed7e4708f 471 SUPERFAMILY SSF50800 67 162 5.41E-20 T 22-04-2016 IPR011037 Pyruvate kinase-like, insert domain HRM2_RS12395 f80f5a4b6c1e439f25538c8ed7e4708f 471 Gene3D G3DSA:3.40.1380.20 320 461 5.4E-27 T 22-04-2016 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS12395 f80f5a4b6c1e439f25538c8ed7e4708f 471 Gene3D G3DSA:3.20.20.60 164 319 3.7E-98 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HRM2_RS12395 f80f5a4b6c1e439f25538c8ed7e4708f 471 Gene3D G3DSA:3.20.20.60 3 69 3.7E-98 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HRM2_RS12395 f80f5a4b6c1e439f25538c8ed7e4708f 471 Pfam PF02887 Pyruvate kinase, alpha/beta domain 351 452 1.8E-15 T 22-04-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS12395 f80f5a4b6c1e439f25538c8ed7e4708f 471 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 3 460 2.6E-150 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS12395 f80f5a4b6c1e439f25538c8ed7e4708f 471 SUPERFAMILY SSF51621 151 331 2.62E-88 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HRM2_RS12395 f80f5a4b6c1e439f25538c8ed7e4708f 471 SUPERFAMILY SSF51621 2 71 2.62E-88 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HRM2_RS12395 f80f5a4b6c1e439f25538c8ed7e4708f 471 Pfam PF00224 Pyruvate kinase, barrel domain 3 332 2.1E-116 T 22-04-2016 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS12395 f80f5a4b6c1e439f25538c8ed7e4708f 471 PANTHER PTHR11817:SF3 1 447 6.6E-169 T 22-04-2016 HRM2_RS12395 f80f5a4b6c1e439f25538c8ed7e4708f 471 PANTHER PTHR11817 1 447 6.6E-169 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS16225 33274dda737c310413a28b6c6fd2db6e 83 SUPERFAMILY SSF52833 37 83 8.54E-16 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS16225 33274dda737c310413a28b6c6fd2db6e 83 Gene3D G3DSA:3.40.30.10 33 83 2.2E-16 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS16225 33274dda737c310413a28b6c6fd2db6e 83 Pfam PF00578 AhpC/TSA family 41 83 1.3E-10 T 22-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 HRM2_RS16225 33274dda737c310413a28b6c6fd2db6e 83 PANTHER PTHR10681:SF121 37 83 7.4E-15 T 22-04-2016 HRM2_RS16225 33274dda737c310413a28b6c6fd2db6e 83 PANTHER PTHR10681 37 83 7.4E-15 T 22-04-2016 HRM2_RS25185 0902f0afc7a89139b83d0da64babae31 557 SUPERFAMILY SSF50494 332 454 3.87E-6 T 22-04-2016 IPR009003 Peptidase S1, PA clan HRM2_RS25185 0902f0afc7a89139b83d0da64babae31 557 Gene3D G3DSA:2.40.10.10 358 456 3.7E-7 T 22-04-2016 HRM2_RS04615 c62d39cfbe26d95ea95ecc4cddad36b4 103 SUPERFAMILY SSF47413 12 86 3.1E-23 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS04615 c62d39cfbe26d95ea95ecc4cddad36b4 103 SMART SM00530 14 70 3.5E-6 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS04615 c62d39cfbe26d95ea95ecc4cddad36b4 103 Gene3D G3DSA:1.10.260.40 3 88 4.3E-31 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS04615 c62d39cfbe26d95ea95ecc4cddad36b4 103 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 5 83 2.0E-31 T 22-04-2016 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 HRM2_RS04615 c62d39cfbe26d95ea95ecc4cddad36b4 103 PANTHER PTHR36924:SF2 2 94 1.1E-28 T 22-04-2016 HRM2_RS04615 c62d39cfbe26d95ea95ecc4cddad36b4 103 Pfam PF01381 Helix-turn-helix 18 68 5.6E-12 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS04615 c62d39cfbe26d95ea95ecc4cddad36b4 103 PANTHER PTHR36924 2 94 1.1E-28 T 22-04-2016 HRM2_RS06155 2f7c5211e9a2e4f2a0b7c122d23e6c86 415 PANTHER PTHR10836:SF50 9 344 4.1E-82 T 22-04-2016 HRM2_RS06155 2f7c5211e9a2e4f2a0b7c122d23e6c86 415 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 187 194 - T 22-04-2016 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS06155 2f7c5211e9a2e4f2a0b7c122d23e6c86 415 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 194 352 9.0E-27 T 22-04-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS06155 2f7c5211e9a2e4f2a0b7c122d23e6c86 415 Gene3D G3DSA:3.40.50.720 9 197 1.0E-42 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS06155 2f7c5211e9a2e4f2a0b7c122d23e6c86 415 Gene3D G3DSA:3.30.360.10 198 395 2.7E-43 T 22-04-2016 HRM2_RS06155 2f7c5211e9a2e4f2a0b7c122d23e6c86 415 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 9 189 1.6E-32 T 22-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS06155 2f7c5211e9a2e4f2a0b7c122d23e6c86 415 SMART SM00846 6 189 4.5E-27 T 22-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS06155 2f7c5211e9a2e4f2a0b7c122d23e6c86 415 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 183 201 8.3E-18 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS06155 2f7c5211e9a2e4f2a0b7c122d23e6c86 415 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 319 334 8.3E-18 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS06155 2f7c5211e9a2e4f2a0b7c122d23e6c86 415 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 138 151 8.3E-18 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS06155 2f7c5211e9a2e4f2a0b7c122d23e6c86 415 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 274 291 8.3E-18 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS06155 2f7c5211e9a2e4f2a0b7c122d23e6c86 415 PANTHER PTHR10836 9 344 4.1E-82 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS06155 2f7c5211e9a2e4f2a0b7c122d23e6c86 415 SUPERFAMILY SSF55347 189 344 3.12E-31 T 22-04-2016 HRM2_RS06155 2f7c5211e9a2e4f2a0b7c122d23e6c86 415 SUPERFAMILY SSF51735 9 205 4.34E-37 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS15125 e3fa4b90a99cce0ba2432fd2d9c0693a 314 SMART SM00244 20 210 5.6E-28 T 22-04-2016 IPR001107 Band 7 domain HRM2_RS15125 e3fa4b90a99cce0ba2432fd2d9c0693a 314 PIRSF PIRSF005651 1 314 5.6E-102 T 22-04-2016 IPR010200 HflC GO:0016021|GO:0052547 HRM2_RS15125 e3fa4b90a99cce0ba2432fd2d9c0693a 314 PANTHER PTHR10264:SF80 6 140 1.4E-64 T 22-04-2016 HRM2_RS15125 e3fa4b90a99cce0ba2432fd2d9c0693a 314 PANTHER PTHR10264:SF80 167 310 1.4E-64 T 22-04-2016 HRM2_RS15125 e3fa4b90a99cce0ba2432fd2d9c0693a 314 PANTHER PTHR10264 6 140 1.4E-64 T 22-04-2016 IPR001972 Stomatin family GO:0016020 HRM2_RS15125 e3fa4b90a99cce0ba2432fd2d9c0693a 314 PANTHER PTHR10264 167 310 1.4E-64 T 22-04-2016 IPR001972 Stomatin family GO:0016020 HRM2_RS15125 e3fa4b90a99cce0ba2432fd2d9c0693a 314 SUPERFAMILY SSF117892 53 137 4.71E-20 T 22-04-2016 IPR001107 Band 7 domain HRM2_RS15125 e3fa4b90a99cce0ba2432fd2d9c0693a 314 SUPERFAMILY SSF117892 166 215 4.71E-20 T 22-04-2016 IPR001107 Band 7 domain HRM2_RS15125 e3fa4b90a99cce0ba2432fd2d9c0693a 314 Pfam PF01145 SPFH domain / Band 7 family 23 225 6.6E-29 T 22-04-2016 IPR001107 Band 7 domain HRM2_RS15125 e3fa4b90a99cce0ba2432fd2d9c0693a 314 TIGRFAM TIGR01932 hflC: HflC protein 6 308 1.5E-88 T 22-04-2016 IPR010200 HflC GO:0016021|GO:0052547 HRM2_RS12715 6c37912764c19596d16884d993c19f83 264 Pfam PF10531 SLBB domain 190 234 2.1E-9 T 22-04-2016 IPR019554 Soluble ligand binding domain HRM2_RS12715 6c37912764c19596d16884d993c19f83 264 Pfam PF10531 SLBB domain 104 139 4.2E-6 T 22-04-2016 IPR019554 Soluble ligand binding domain HRM2_RS12715 6c37912764c19596d16884d993c19f83 264 PANTHER PTHR33619 24 264 5.7E-42 T 22-04-2016 HRM2_RS12715 6c37912764c19596d16884d993c19f83 264 Pfam PF02563 Polysaccharide biosynthesis/export protein 25 96 7.6E-18 T 22-04-2016 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 HRM2_RS12715 6c37912764c19596d16884d993c19f83 264 Gene3D G3DSA:3.30.1950.10 31 95 5.1E-18 T 22-04-2016 HRM2_RS12715 6c37912764c19596d16884d993c19f83 264 Gene3D G3DSA:3.10.560.10 190 261 3.9E-12 T 22-04-2016 HRM2_RS12715 6c37912764c19596d16884d993c19f83 264 Gene3D G3DSA:3.10.560.10 96 185 1.2E-14 T 22-04-2016 HRM2_RS10490 5722ee65bad09797b301db70cdcde982 543 PANTHER PTHR40050 236 505 2.3E-14 T 22-04-2016 HRM2_RS10490 5722ee65bad09797b301db70cdcde982 543 Pfam PF08757 CotH protein 201 534 2.0E-66 T 22-04-2016 IPR014867 Spore coat protein CotH HRM2_RS20145 f6134dc21dd51ff7ab3cf933e5caf042 277 SUPERFAMILY SSF53850 17 268 5.76E-55 T 22-04-2016 HRM2_RS20145 f6134dc21dd51ff7ab3cf933e5caf042 277 Gene3D G3DSA:3.40.190.10 42 123 1.2E-32 T 22-04-2016 HRM2_RS20145 f6134dc21dd51ff7ab3cf933e5caf042 277 Gene3D G3DSA:3.40.190.10 228 268 1.2E-32 T 22-04-2016 HRM2_RS20145 f6134dc21dd51ff7ab3cf933e5caf042 277 Gene3D G3DSA:3.40.190.10 124 227 1.4E-8 T 22-04-2016 HRM2_RS20145 f6134dc21dd51ff7ab3cf933e5caf042 277 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 48 268 6.9E-45 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS20145 f6134dc21dd51ff7ab3cf933e5caf042 277 PANTHER PTHR18966:SF152 25 272 1.8E-55 T 22-04-2016 HRM2_RS20145 f6134dc21dd51ff7ab3cf933e5caf042 277 PANTHER PTHR18966 25 272 1.8E-55 T 22-04-2016 HRM2_RS20145 f6134dc21dd51ff7ab3cf933e5caf042 277 SMART SM00062 47 270 4.0E-38 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS20145 f6134dc21dd51ff7ab3cf933e5caf042 277 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 69 82 - T 22-04-2016 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 HRM2_RS03745 dbdeadaba9d4e03a6c7b9c1493f9fe44 672 Pfam PF01955 Adenosylcobinamide amidohydrolase 343 536 2.7E-54 T 22-04-2016 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ HRM2_RS03745 dbdeadaba9d4e03a6c7b9c1493f9fe44 672 Pfam PF01497 Periplasmic binding protein 48 268 1.5E-25 T 22-04-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 HRM2_RS03745 dbdeadaba9d4e03a6c7b9c1493f9fe44 672 PANTHER PTHR30535:SF5 13 296 3.6E-50 T 22-04-2016 HRM2_RS03745 dbdeadaba9d4e03a6c7b9c1493f9fe44 672 SUPERFAMILY SSF53807 26 293 2.08E-54 T 22-04-2016 HRM2_RS03745 dbdeadaba9d4e03a6c7b9c1493f9fe44 672 PANTHER PTHR30535 13 296 3.6E-50 T 22-04-2016 HRM2_RS03745 dbdeadaba9d4e03a6c7b9c1493f9fe44 672 Gene3D G3DSA:3.40.50.1980 166 294 2.4E-21 T 22-04-2016 HRM2_RS03745 dbdeadaba9d4e03a6c7b9c1493f9fe44 672 Gene3D G3DSA:3.40.50.1980 42 160 5.2E-23 T 22-04-2016 HRM2_RS22640 9d5ce4f9e98c40bf209f3167e0dfe4a0 665 Gene3D G3DSA:3.40.710.10 238 643 1.4E-130 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HRM2_RS22640 9d5ce4f9e98c40bf209f3167e0dfe4a0 665 Gene3D G3DSA:1.10.3810.10 72 237 5.3E-63 T 22-04-2016 HRM2_RS22640 9d5ce4f9e98c40bf209f3167e0dfe4a0 665 SUPERFAMILY SSF53955 58 261 1.15E-65 T 22-04-2016 IPR023346 Lysozyme-like domain HRM2_RS22640 9d5ce4f9e98c40bf209f3167e0dfe4a0 665 PANTHER PTHR32282 12 637 4.1E-186 T 22-04-2016 HRM2_RS22640 9d5ce4f9e98c40bf209f3167e0dfe4a0 665 Pfam PF00912 Transglycosylase 72 235 1.0E-55 T 22-04-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 HRM2_RS22640 9d5ce4f9e98c40bf209f3167e0dfe4a0 665 SUPERFAMILY SSF56601 217 239 3.3E-123 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HRM2_RS22640 9d5ce4f9e98c40bf209f3167e0dfe4a0 665 SUPERFAMILY SSF56601 267 647 3.3E-123 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HRM2_RS22640 9d5ce4f9e98c40bf209f3167e0dfe4a0 665 Pfam PF00905 Penicillin binding protein transpeptidase domain 333 576 4.9E-29 T 22-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 HRM2_RS22640 9d5ce4f9e98c40bf209f3167e0dfe4a0 665 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 72 615 2.0E-171 T 22-04-2016 HRM2_RS22640 9d5ce4f9e98c40bf209f3167e0dfe4a0 665 PANTHER PTHR32282:SF5 12 637 4.1E-186 T 22-04-2016 HRM2_RS10090 98ffc726e783c6e44e9a0b919e2d1b49 213 PANTHER PTHR30614 1 213 2.1E-66 T 22-04-2016 HRM2_RS10090 98ffc726e783c6e44e9a0b919e2d1b49 213 SUPERFAMILY SSF161098 10 198 6.15E-39 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS10090 98ffc726e783c6e44e9a0b919e2d1b49 213 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 209 2.5E-19 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS10090 98ffc726e783c6e44e9a0b919e2d1b49 213 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 8 104 7.2E-21 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HRM2_RS10090 98ffc726e783c6e44e9a0b919e2d1b49 213 Gene3D G3DSA:1.10.3720.10 10 209 3.3E-41 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS12605 ee5f91a93ade7d0c93a6ecd696091b77 417 Pfam PF04932 O-Antigen ligase 210 348 6.4E-7 T 22-04-2016 IPR007016 O-antigen ligase-related HRM2_RS16810 a67d943d73d4c6ee52f6b83ce7f06a6a 1013 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 2.8E-28 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS16810 a67d943d73d4c6ee52f6b83ce7f06a6a 1013 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 2.8E-28 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS16810 a67d943d73d4c6ee52f6b83ce7f06a6a 1013 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 2.8E-28 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS16810 a67d943d73d4c6ee52f6b83ce7f06a6a 1013 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 2.8E-28 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS16810 a67d943d73d4c6ee52f6b83ce7f06a6a 1013 PRINTS PR00702 Acriflavin resistance protein family signature 437 460 2.8E-28 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS16810 a67d943d73d4c6ee52f6b83ce7f06a6a 1013 PRINTS PR00702 Acriflavin resistance protein family signature 536 553 2.8E-28 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS16810 a67d943d73d4c6ee52f6b83ce7f06a6a 1013 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 2.8E-28 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS16810 a67d943d73d4c6ee52f6b83ce7f06a6a 1013 Gene3D G3DSA:3.30.70.1430 40 140 4.3E-24 T 22-04-2016 HRM2_RS16810 a67d943d73d4c6ee52f6b83ce7f06a6a 1013 PANTHER PTHR32063 1 1011 0.0 T 22-04-2016 HRM2_RS16810 a67d943d73d4c6ee52f6b83ce7f06a6a 1013 SUPERFAMILY SSF82693 40 135 2.3E-19 T 22-04-2016 HRM2_RS16810 a67d943d73d4c6ee52f6b83ce7f06a6a 1013 Gene3D G3DSA:3.30.2090.10 185 265 5.0E-10 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS16810 a67d943d73d4c6ee52f6b83ce7f06a6a 1013 Gene3D G3DSA:3.30.2090.10 707 784 8.6E-6 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS16810 a67d943d73d4c6ee52f6b83ce7f06a6a 1013 PANTHER PTHR32063:SF18 1 1011 0.0 T 22-04-2016 HRM2_RS16810 a67d943d73d4c6ee52f6b83ce7f06a6a 1013 SUPERFAMILY SSF82693 136 182 8.11E-19 T 22-04-2016 HRM2_RS16810 a67d943d73d4c6ee52f6b83ce7f06a6a 1013 SUPERFAMILY SSF82693 268 323 8.11E-19 T 22-04-2016 HRM2_RS16810 a67d943d73d4c6ee52f6b83ce7f06a6a 1013 Gene3D G3DSA:1.10.3850.10 273 490 2.1E-45 T 22-04-2016 HRM2_RS16810 a67d943d73d4c6ee52f6b83ce7f06a6a 1013 Gene3D G3DSA:1.10.3850.10 796 1005 5.7E-56 T 22-04-2016 HRM2_RS16810 a67d943d73d4c6ee52f6b83ce7f06a6a 1013 SUPERFAMILY SSF82866 788 1007 4.71E-47 T 22-04-2016 HRM2_RS16810 a67d943d73d4c6ee52f6b83ce7f06a6a 1013 SUPERFAMILY SSF82866 291 490 2.35E-37 T 22-04-2016 HRM2_RS16810 a67d943d73d4c6ee52f6b83ce7f06a6a 1013 Pfam PF00873 AcrB/AcrD/AcrF family 4 1003 5.0E-163 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS16810 a67d943d73d4c6ee52f6b83ce7f06a6a 1013 SUPERFAMILY SSF82714 704 784 2.75E-9 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS16810 a67d943d73d4c6ee52f6b83ce7f06a6a 1013 SUPERFAMILY SSF82714 185 265 3.66E-9 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HRM2_RS13230 3cc0fede371a47781a3bb20845d7bd6a 62 SUPERFAMILY SSF54862 5 60 4.19E-18 T 22-04-2016 HRM2_RS13230 3cc0fede371a47781a3bb20845d7bd6a 62 Pfam PF13187 4Fe-4S dicluster domain 11 57 9.0E-10 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS13230 3cc0fede371a47781a3bb20845d7bd6a 62 PANTHER PTHR24960 1 62 5.0E-13 T 22-04-2016 HRM2_RS13230 3cc0fede371a47781a3bb20845d7bd6a 62 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 42 53 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS13230 3cc0fede371a47781a3bb20845d7bd6a 62 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 12 23 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS13230 3cc0fede371a47781a3bb20845d7bd6a 62 Gene3D G3DSA:3.30.70.20 4 61 1.6E-18 T 22-04-2016 HRM2_RS00445 beb5e7f36e34d8241287ebe9b323dcda 586 SUPERFAMILY SSF51905 52 256 1.65E-41 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS00445 beb5e7f36e34d8241287ebe9b323dcda 586 SUPERFAMILY SSF51905 379 438 1.65E-41 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS00445 beb5e7f36e34d8241287ebe9b323dcda 586 Gene3D G3DSA:3.50.50.60 378 433 1.8E-39 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS00445 beb5e7f36e34d8241287ebe9b323dcda 586 Gene3D G3DSA:3.50.50.60 55 251 1.8E-39 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS00445 beb5e7f36e34d8241287ebe9b323dcda 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 393 400 1.5E-5 T 22-04-2016 HRM2_RS00445 beb5e7f36e34d8241287ebe9b323dcda 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 60 82 1.5E-5 T 22-04-2016 HRM2_RS00445 beb5e7f36e34d8241287ebe9b323dcda 586 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 210 228 3.2E-11 T 22-04-2016 HRM2_RS00445 beb5e7f36e34d8241287ebe9b323dcda 586 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 378 400 3.2E-11 T 22-04-2016 HRM2_RS00445 beb5e7f36e34d8241287ebe9b323dcda 586 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 61 80 3.2E-11 T 22-04-2016 HRM2_RS00445 beb5e7f36e34d8241287ebe9b323dcda 586 PANTHER PTHR11632 380 580 3.5E-22 T 22-04-2016 HRM2_RS00445 beb5e7f36e34d8241287ebe9b323dcda 586 Pfam PF02910 Fumarate reductase flavoprotein C-term 472 582 2.8E-11 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 HRM2_RS00445 beb5e7f36e34d8241287ebe9b323dcda 586 Pfam PF00890 FAD binding domain 60 155 1.2E-9 T 22-04-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain HRM2_RS00445 beb5e7f36e34d8241287ebe9b323dcda 586 SUPERFAMILY SSF46977 462 582 2.88E-26 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 HRM2_RS00445 beb5e7f36e34d8241287ebe9b323dcda 586 Gene3D G3DSA:1.20.58.100 442 555 7.3E-28 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 HRM2_RS00445 beb5e7f36e34d8241287ebe9b323dcda 586 PANTHER PTHR11632:SF6 380 580 3.5E-22 T 22-04-2016 HRM2_RS03905 8b65f4c17da35fb6a1efeb1e2c7602df 260 SUPERFAMILY SSF52540 9 241 1.33E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03905 8b65f4c17da35fb6a1efeb1e2c7602df 260 Gene3D G3DSA:3.40.50.300 3 224 3.9E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03905 8b65f4c17da35fb6a1efeb1e2c7602df 260 SMART SM00382 38 233 1.1E-16 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS03905 8b65f4c17da35fb6a1efeb1e2c7602df 260 Pfam PF00005 ABC transporter 29 168 6.2E-32 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS03905 8b65f4c17da35fb6a1efeb1e2c7602df 260 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS03905 8b65f4c17da35fb6a1efeb1e2c7602df 260 PANTHER PTHR24220 10 247 3.1E-91 T 22-04-2016 HRM2_RS03905 8b65f4c17da35fb6a1efeb1e2c7602df 260 PANTHER PTHR24220:SF589 10 247 3.1E-91 T 22-04-2016 HRM2_RS12470 7cce465ee4c0e93e516f602b72c8a6d9 859 SMART SM00382 599 765 6.7E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS12470 7cce465ee4c0e93e516f602b72c8a6d9 859 SMART SM00382 197 341 1.3E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS12470 7cce465ee4c0e93e516f602b72c8a6d9 859 SUPERFAMILY SSF81923 4 155 1.86E-35 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 HRM2_RS12470 7cce465ee4c0e93e516f602b72c8a6d9 859 Gene3D G3DSA:1.10.8.60 342 426 3.6E-35 T 22-04-2016 HRM2_RS12470 7cce465ee4c0e93e516f602b72c8a6d9 859 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 850 0.0 T 22-04-2016 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 HRM2_RS12470 7cce465ee4c0e93e516f602b72c8a6d9 859 PANTHER PTHR11638 1 854 0.0 T 22-04-2016 HRM2_RS12470 7cce465ee4c0e93e516f602b72c8a6d9 859 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 202 319 7.0E-13 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HRM2_RS12470 7cce465ee4c0e93e516f602b72c8a6d9 859 SUPERFAMILY SSF52540 156 546 6.17E-93 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12470 7cce465ee4c0e93e516f602b72c8a6d9 859 PANTHER PTHR11638:SF18 1 854 0.0 T 22-04-2016 HRM2_RS12470 7cce465ee4c0e93e516f602b72c8a6d9 859 Gene3D G3DSA:1.10.1780.10 1 148 9.6E-34 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 HRM2_RS12470 7cce465ee4c0e93e516f602b72c8a6d9 859 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 1.1E-7 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 HRM2_RS12470 7cce465ee4c0e93e516f602b72c8a6d9 859 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 144 2.5E-8 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 HRM2_RS12470 7cce465ee4c0e93e516f602b72c8a6d9 859 SMART SM01086 764 855 2.3E-36 T 22-04-2016 IPR019489 Clp ATPase, C-terminal HRM2_RS12470 7cce465ee4c0e93e516f602b72c8a6d9 859 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 764 843 4.5E-27 T 22-04-2016 IPR019489 Clp ATPase, C-terminal HRM2_RS12470 7cce465ee4c0e93e516f602b72c8a6d9 859 SUPERFAMILY SSF52540 548 847 3.09E-77 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12470 7cce465ee4c0e93e516f602b72c8a6d9 859 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 633 651 - T 22-04-2016 IPR028299 ClpA/B, conserved site 2 HRM2_RS12470 7cce465ee4c0e93e516f602b72c8a6d9 859 Gene3D G3DSA:3.40.50.300 158 340 8.9E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12470 7cce465ee4c0e93e516f602b72c8a6d9 859 Gene3D G3DSA:1.10.8.60 776 854 2.6E-31 T 22-04-2016 HRM2_RS12470 7cce465ee4c0e93e516f602b72c8a6d9 859 Pfam PF07724 AAA domain (Cdc48 subfamily) 598 758 1.2E-55 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HRM2_RS12470 7cce465ee4c0e93e516f602b72c8a6d9 859 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 293 305 - T 22-04-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 HRM2_RS12470 7cce465ee4c0e93e516f602b72c8a6d9 859 Gene3D G3DSA:3.40.50.300 554 775 6.1E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12470 7cce465ee4c0e93e516f602b72c8a6d9 859 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 648 666 6.2E-42 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 HRM2_RS12470 7cce465ee4c0e93e516f602b72c8a6d9 859 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 603 621 6.2E-42 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 HRM2_RS12470 7cce465ee4c0e93e516f602b72c8a6d9 859 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 677 695 6.2E-42 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 HRM2_RS12470 7cce465ee4c0e93e516f602b72c8a6d9 859 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 710 724 6.2E-42 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 HRM2_RS06265 5d4395dbf788ebedd3b8fc221cb20522 312 SUPERFAMILY SSF53335 216 311 3.49E-40 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS06265 5d4395dbf788ebedd3b8fc221cb20522 312 SUPERFAMILY SSF53335 5 113 3.49E-40 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS06265 5d4395dbf788ebedd3b8fc221cb20522 312 SUPERFAMILY SSF81799 113 215 4.84E-34 T 22-04-2016 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HRM2_RS06265 5d4395dbf788ebedd3b8fc221cb20522 312 PANTHER PTHR11265:SF0 1 312 9.9E-127 T 22-04-2016 HRM2_RS06265 5d4395dbf788ebedd3b8fc221cb20522 312 Gene3D G3DSA:3.40.50.150 219 311 3.1E-44 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS06265 5d4395dbf788ebedd3b8fc221cb20522 312 Gene3D G3DSA:3.40.50.150 5 110 3.1E-44 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS06265 5d4395dbf788ebedd3b8fc221cb20522 312 PIRSF PIRSF004486 1 312 1.0E-103 T 22-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HRM2_RS06265 5d4395dbf788ebedd3b8fc221cb20522 312 PANTHER PTHR11265 1 312 9.9E-127 T 22-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HRM2_RS06265 5d4395dbf788ebedd3b8fc221cb20522 312 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 3 309 3.7E-104 T 22-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HRM2_RS06265 5d4395dbf788ebedd3b8fc221cb20522 312 Gene3D G3DSA:1.10.150.170 113 218 1.2E-38 T 22-04-2016 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HRM2_RS06265 5d4395dbf788ebedd3b8fc221cb20522 312 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 5 312 36.467 T 22-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HRM2_RS06265 5d4395dbf788ebedd3b8fc221cb20522 312 Pfam PF01795 MraW methylase family 3 309 5.1E-113 T 22-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HRM2_RS19375 3ecbba46d9d7bc76ce5ecf588652c308 552 Gene3D G3DSA:3.60.21.10 43 343 2.7E-23 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS19375 3ecbba46d9d7bc76ce5ecf588652c308 552 Pfam PF00149 Calcineurin-like phosphoesterase 48 274 5.1E-8 T 22-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 HRM2_RS19375 3ecbba46d9d7bc76ce5ecf588652c308 552 SUPERFAMILY SSF56300 46 344 1.52E-26 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS20110 82f2bdf825f90ae10651538927bbd032 193 PANTHER PTHR32154:SF22 1 77 1.3E-20 T 22-04-2016 HRM2_RS20110 82f2bdf825f90ae10651538927bbd032 193 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 187 1.9E-26 T 22-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HRM2_RS20110 82f2bdf825f90ae10651538927bbd032 193 SUPERFAMILY SSF53323 4 183 8.11E-23 T 22-04-2016 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 HRM2_RS20110 82f2bdf825f90ae10651538927bbd032 193 PANTHER PTHR32154 1 77 1.3E-20 T 22-04-2016 HRM2_RS20110 82f2bdf825f90ae10651538927bbd032 193 Gene3D G3DSA:3.40.920.10 4 187 2.3E-27 T 22-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HRM2_RS09435 058de7339555328336bc47bda7ba9c8d 224 PANTHER PTHR39425 20 213 3.4E-17 T 22-04-2016 HRM2_RS09435 058de7339555328336bc47bda7ba9c8d 224 SUPERFAMILY SSF48695 66 223 3.65E-15 T 22-04-2016 IPR011031 Multihaem cytochrome HRM2_RS09435 058de7339555328336bc47bda7ba9c8d 224 Pfam PF14522 Cytochrome c7 and related cytochrome c 142 224 3.4E-8 T 22-04-2016 HRM2_RS09435 058de7339555328336bc47bda7ba9c8d 224 Pfam PF02085 Class III cytochrome C family 61 115 5.2E-5 T 22-04-2016 IPR020942 Class III cytochrome C GO:0009055|GO:0020037 HRM2_RS09435 058de7339555328336bc47bda7ba9c8d 224 PANTHER PTHR39425:SF1 20 213 3.4E-17 T 22-04-2016 HRM2_RS09435 058de7339555328336bc47bda7ba9c8d 224 Gene3D G3DSA:3.90.10.10 132 224 3.5E-12 T 22-04-2016 HRM2_RS09435 058de7339555328336bc47bda7ba9c8d 224 Gene3D G3DSA:3.90.10.10 59 108 8.7E-7 T 22-04-2016 HRM2_RS00940 4dc815a4154998ebe7428cd05ef44bb7 168 Pfam PF00293 NUDIX domain 20 139 5.0E-18 T 22-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 HRM2_RS00940 4dc815a4154998ebe7428cd05ef44bb7 168 PANTHER PTHR22769 19 152 1.0E-28 T 22-04-2016 HRM2_RS00940 4dc815a4154998ebe7428cd05ef44bb7 168 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 95 114 3.3E-10 T 22-04-2016 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502 HRM2_RS00940 4dc815a4154998ebe7428cd05ef44bb7 168 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 134 152 3.3E-10 T 22-04-2016 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502 HRM2_RS00940 4dc815a4154998ebe7428cd05ef44bb7 168 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 35 51 3.3E-10 T 22-04-2016 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502 HRM2_RS00940 4dc815a4154998ebe7428cd05ef44bb7 168 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 115 133 3.3E-10 T 22-04-2016 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502 HRM2_RS00940 4dc815a4154998ebe7428cd05ef44bb7 168 SUPERFAMILY SSF55811 17 144 7.18E-28 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HRM2_RS00940 4dc815a4154998ebe7428cd05ef44bb7 168 Gene3D G3DSA:3.90.79.10 20 157 4.3E-44 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HRM2_RS00940 4dc815a4154998ebe7428cd05ef44bb7 168 PRINTS PR00502 NUDIX hydrolase family signature 46 60 1.4E-6 T 22-04-2016 IPR020476 NUDIX hydrolase HRM2_RS00940 4dc815a4154998ebe7428cd05ef44bb7 168 PRINTS PR00502 NUDIX hydrolase family signature 60 75 1.4E-6 T 22-04-2016 IPR020476 NUDIX hydrolase HRM2_RS18155 9b9deabc047d8f42c201c2a3f40348eb 209 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 6 205 35.119 T 22-04-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UniPathway: UPA00031 HRM2_RS18155 9b9deabc047d8f42c201c2a3f40348eb 209 PANTHER PTHR21235:SF1 7 202 3.9E-78 T 22-04-2016 HRM2_RS18155 9b9deabc047d8f42c201c2a3f40348eb 209 Gene3D G3DSA:3.40.50.880 4 205 2.9E-75 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS18155 9b9deabc047d8f42c201c2a3f40348eb 209 Pfam PF00117 Glutamine amidotransferase class-I 10 202 2.5E-18 T 22-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 HRM2_RS18155 9b9deabc047d8f42c201c2a3f40348eb 209 PIRSF PIRSF000495 5 208 1.5E-74 T 22-04-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UniPathway: UPA00031 HRM2_RS18155 9b9deabc047d8f42c201c2a3f40348eb 209 PANTHER PTHR21235 7 202 3.9E-78 T 22-04-2016 HRM2_RS18155 9b9deabc047d8f42c201c2a3f40348eb 209 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 7 204 7.3E-73 T 22-04-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UniPathway: UPA00031 HRM2_RS18155 9b9deabc047d8f42c201c2a3f40348eb 209 SUPERFAMILY SSF52317 7 196 4.73E-53 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS03350 292da3981b339182fb8f90f00e78c19d 309 TIGRFAM TIGR01139 cysK: cysteine synthase A 11 305 6.4E-131 T 22-04-2016 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936|UniPathway: UPA00136 HRM2_RS03350 292da3981b339182fb8f90f00e78c19d 309 SUPERFAMILY SSF53686 2 306 6.42E-100 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HRM2_RS03350 292da3981b339182fb8f90f00e78c19d 309 Gene3D G3DSA:3.40.50.1100 135 305 1.1E-74 T 22-04-2016 HRM2_RS03350 292da3981b339182fb8f90f00e78c19d 309 TIGRFAM TIGR01136 cysKM: cysteine synthase 11 305 6.2E-128 T 22-04-2016 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936|UniPathway: UPA00136 HRM2_RS03350 292da3981b339182fb8f90f00e78c19d 309 PANTHER PTHR10314:SF110 1 305 9.0E-157 T 22-04-2016 HRM2_RS03350 292da3981b339182fb8f90f00e78c19d 309 Gene3D G3DSA:3.40.50.1100 38 134 2.0E-39 T 22-04-2016 HRM2_RS03350 292da3981b339182fb8f90f00e78c19d 309 PANTHER PTHR10314 1 305 9.0E-157 T 22-04-2016 HRM2_RS03350 292da3981b339182fb8f90f00e78c19d 309 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 294 2.2E-66 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HRM2_RS14250 6e593b1c09dc36407ee98f3c48b88a28 229 SUPERFAMILY SSF55021 146 208 2.58E-5 T 22-04-2016 HRM2_RS14250 6e593b1c09dc36407ee98f3c48b88a28 229 PANTHER PTHR11911 1 133 5.4E-32 T 22-04-2016 HRM2_RS14250 6e593b1c09dc36407ee98f3c48b88a28 229 SUPERFAMILY SSF54631 1 133 1.13E-34 T 22-04-2016 HRM2_RS14250 6e593b1c09dc36407ee98f3c48b88a28 229 Pfam PF00571 CBS domain 7 55 4.0E-12 T 22-04-2016 IPR000644 CBS domain HRM2_RS14250 6e593b1c09dc36407ee98f3c48b88a28 229 Pfam PF00571 CBS domain 79 133 1.4E-14 T 22-04-2016 IPR000644 CBS domain HRM2_RS14250 6e593b1c09dc36407ee98f3c48b88a28 229 SMART SM00116 10 58 5.8E-12 T 22-04-2016 IPR000644 CBS domain HRM2_RS14250 6e593b1c09dc36407ee98f3c48b88a28 229 SMART SM00116 86 134 7.9E-10 T 22-04-2016 IPR000644 CBS domain HRM2_RS14250 6e593b1c09dc36407ee98f3c48b88a28 229 Gene3D G3DSA:3.10.580.10 2 134 2.6E-32 T 22-04-2016 HRM2_RS14250 6e593b1c09dc36407ee98f3c48b88a28 229 Gene3D G3DSA:3.30.70.260 146 206 1.5E-4 T 22-04-2016 HRM2_RS07895 ff6ac1c1853efbe0036556b1823663a6 465 Pfam PF13520 Amino acid permease 22 437 3.0E-54 T 22-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 HRM2_RS07895 ff6ac1c1853efbe0036556b1823663a6 465 PANTHER PTHR11785:SF216 2 435 2.6E-65 T 22-04-2016 HRM2_RS07895 ff6ac1c1853efbe0036556b1823663a6 465 PIRSF PIRSF006060 1 465 2.0E-64 T 22-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 HRM2_RS07895 ff6ac1c1853efbe0036556b1823663a6 465 PANTHER PTHR11785 2 435 2.6E-65 T 22-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 HRM2_RS19975 38f4571b9f6c0c34eec0d7b8424bd671 282 Gene3D G3DSA:3.30.200.20 16 125 1.2E-12 T 22-04-2016 HRM2_RS19975 38f4571b9f6c0c34eec0d7b8424bd671 282 SUPERFAMILY SSF56112 18 214 4.71E-22 T 22-04-2016 IPR011009 Protein kinase-like domain HRM2_RS19975 38f4571b9f6c0c34eec0d7b8424bd671 282 Gene3D G3DSA:1.10.510.10 140 216 4.0E-18 T 22-04-2016 HRM2_RS19975 38f4571b9f6c0c34eec0d7b8424bd671 282 PANTHER PTHR10593:SF19 6 277 1.1E-125 T 22-04-2016 HRM2_RS19975 38f4571b9f6c0c34eec0d7b8424bd671 282 SMART SM00090 5 235 3.9E-13 T 22-04-2016 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 HRM2_RS19975 38f4571b9f6c0c34eec0d7b8424bd671 282 PANTHER PTHR10593 6 277 1.1E-125 T 22-04-2016 HRM2_RS19975 38f4571b9f6c0c34eec0d7b8424bd671 282 Pfam PF01163 RIO1 family 31 219 4.0E-41 T 22-04-2016 HRM2_RS19975 38f4571b9f6c0c34eec0d7b8424bd671 282 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 164 175 - T 22-04-2016 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 HRM2_RS05950 99068207e7722919d54375da626c99c2 395 Gene3D G3DSA:3.40.50.300 161 367 2.3E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05950 99068207e7722919d54375da626c99c2 395 PANTHER PTHR40690:SF1 15 376 2.5E-94 T 22-04-2016 HRM2_RS05950 99068207e7722919d54375da626c99c2 395 SUPERFAMILY SSF52540 23 368 1.65E-79 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05950 99068207e7722919d54375da626c99c2 395 PANTHER PTHR40690 15 376 2.5E-94 T 22-04-2016 HRM2_RS05950 99068207e7722919d54375da626c99c2 395 Gene3D G3DSA:3.40.50.720 16 159 1.8E-42 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS05950 99068207e7722919d54375da626c99c2 395 Pfam PF07755 Protein of unknown function (DUF1611) 57 363 1.0E-75 T 22-04-2016 IPR011669 Protein of unknown function DUF1611 HRM2_RS05950 99068207e7722919d54375da626c99c2 395 PIRSF PIRSF026760 21 372 1.1E-89 T 22-04-2016 IPR011669 Protein of unknown function DUF1611 HRM2_RS13515 2e7e75c1173b4ad4b5a7c1ef66bf9bc3 218 PANTHER PTHR14614 56 191 1.8E-27 T 22-04-2016 HRM2_RS13515 2e7e75c1173b4ad4b5a7c1ef66bf9bc3 218 Gene3D G3DSA:3.40.50.150 34 193 1.3E-31 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS13515 2e7e75c1173b4ad4b5a7c1ef66bf9bc3 218 Pfam PF10294 Lysine methyltransferase 56 191 2.2E-15 T 22-04-2016 IPR019410 Lysine methyltransferase HRM2_RS13515 2e7e75c1173b4ad4b5a7c1ef66bf9bc3 218 SUPERFAMILY SSF53335 62 193 9.34E-25 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS09830 d45744c79661387edf62209ccd6c865e 227 Pfam PF02517 CAAX protease self-immunity 99 213 6.6E-17 T 22-04-2016 IPR003675 CAAX amino terminal protease GO:0016020 HRM2_RS09275 7c3816589915a5b4a7a65536cbb65678 456 Gene3D G3DSA:3.40.50.300 175 448 4.7E-104 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09275 7c3816589915a5b4a7a65536cbb65678 456 Gene3D G3DSA:1.10.860.10 15 115 6.8E-34 T 22-04-2016 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal HRM2_RS09275 7c3816589915a5b4a7a65536cbb65678 456 Pfam PF03796 DnaB-like helicase C terminal domain 190 446 8.9E-115 T 22-04-2016 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 HRM2_RS09275 7c3816589915a5b4a7a65536cbb65678 456 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 15 448 9.4E-169 T 22-04-2016 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 HRM2_RS09275 7c3816589915a5b4a7a65536cbb65678 456 PANTHER PTHR30153 1 456 2.8E-199 T 22-04-2016 HRM2_RS09275 7c3816589915a5b4a7a65536cbb65678 456 Pfam PF00772 DnaB-like helicase N terminal domain 15 115 1.5E-33 T 22-04-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 HRM2_RS09275 7c3816589915a5b4a7a65536cbb65678 456 SUPERFAMILY SSF52540 188 438 1.3E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09275 7c3816589915a5b4a7a65536cbb65678 456 SUPERFAMILY SSF48024 13 124 7.32E-35 T 22-04-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 HRM2_RS08005 0e2b0b9f5fa98a99e55bf3c7e3a3012a 249 Pfam PF01925 Sulfite exporter TauE/SafE 9 243 2.5E-43 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 HRM2_RS08005 0e2b0b9f5fa98a99e55bf3c7e3a3012a 249 PANTHER PTHR30269:SF20 1 248 1.5E-72 T 22-04-2016 HRM2_RS08005 0e2b0b9f5fa98a99e55bf3c7e3a3012a 249 PANTHER PTHR30269 1 248 1.5E-72 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 HRM2_RS06735 5349dbf0623d9d82d51b1bd5819f8528 200 SUPERFAMILY SSF56784 1 189 4.07E-41 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS06735 5349dbf0623d9d82d51b1bd5819f8528 200 Pfam PF00702 haloacid dehalogenase-like hydrolase 59 164 1.6E-10 T 22-04-2016 HRM2_RS06735 5349dbf0623d9d82d51b1bd5819f8528 200 Gene3D G3DSA:3.40.50.1000 130 178 9.4E-8 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS06735 5349dbf0623d9d82d51b1bd5819f8528 200 TIGRFAM TIGR02137 HSK-PSP: phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein 2 193 1.8E-90 T 22-04-2016 IPR011863 Phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|UniPathway: UPA00135 HRM2_RS06735 5349dbf0623d9d82d51b1bd5819f8528 200 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 48 160 4.4E-13 T 22-04-2016 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 HRM2_RS06735 5349dbf0623d9d82d51b1bd5819f8528 200 Gene3D G3DSA:3.90.1470.10 13 128 1.9E-43 T 22-04-2016 HRM2_RS23385 f404eaf4d94b760b6681a0328ff771ac 305 Gene3D G3DSA:3.40.50.300 35 270 3.4E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23385 f404eaf4d94b760b6681a0328ff771ac 305 Pfam PF00005 ABC transporter 61 207 3.6E-23 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS23385 f404eaf4d94b760b6681a0328ff771ac 305 PANTHER PTHR24220 46 268 7.0E-74 T 22-04-2016 HRM2_RS23385 f404eaf4d94b760b6681a0328ff771ac 305 SUPERFAMILY SSF52540 36 272 3.91E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23385 f404eaf4d94b760b6681a0328ff771ac 305 PANTHER PTHR24220:SF66 46 268 7.0E-74 T 22-04-2016 HRM2_RS23385 f404eaf4d94b760b6681a0328ff771ac 305 SMART SM00382 70 246 6.1E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS22405 7bb60dd6c01a908a1630652e8b9243eb 285 PANTHER PTHR30193:SF10 4 277 8.1E-81 T 22-04-2016 HRM2_RS22405 7bb60dd6c01a908a1630652e8b9243eb 285 PANTHER PTHR30193 4 277 8.1E-81 T 22-04-2016 HRM2_RS22405 7bb60dd6c01a908a1630652e8b9243eb 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 68 269 1.7E-7 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS22405 7bb60dd6c01a908a1630652e8b9243eb 285 Gene3D G3DSA:1.10.3720.10 3 271 4.6E-43 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS22405 7bb60dd6c01a908a1630652e8b9243eb 285 SUPERFAMILY SSF161098 17 271 1.4E-48 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS17770 b32c6465c633bdb8f0d4c305dd31a3e7 342 PANTHER PTHR10799:SF710 56 336 1.8E-16 T 22-04-2016 HRM2_RS17770 b32c6465c633bdb8f0d4c305dd31a3e7 342 PANTHER PTHR10799 56 336 1.8E-16 T 22-04-2016 HRM2_RS17770 b32c6465c633bdb8f0d4c305dd31a3e7 342 Gene3D G3DSA:3.30.450.40 21 181 1.0E-5 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS17770 b32c6465c633bdb8f0d4c305dd31a3e7 342 SUPERFAMILY SSF55073 187 338 1.18E-41 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS17770 b32c6465c633bdb8f0d4c305dd31a3e7 342 Pfam PF00990 Diguanylate cyclase, GGDEF domain 182 338 9.4E-43 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS17770 b32c6465c633bdb8f0d4c305dd31a3e7 342 SUPERFAMILY SSF55781 33 182 3.43E-12 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS17770 b32c6465c633bdb8f0d4c305dd31a3e7 342 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 178 338 4.3E-48 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS17770 b32c6465c633bdb8f0d4c305dd31a3e7 342 SMART SM00267 171 342 1.6E-41 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS17770 b32c6465c633bdb8f0d4c305dd31a3e7 342 Gene3D G3DSA:3.30.70.270 183 338 2.4E-47 T 22-04-2016 HRM2_RS17370 e3fd3d8ce08e5e7750cc545d93e64820 298 SUPERFAMILY SSF52943 2 297 1.19E-75 T 22-04-2016 IPR023633 ATPase, F1 complex, gamma subunit domain HRM2_RS17370 e3fd3d8ce08e5e7750cc545d93e64820 298 PANTHER PTHR11693 1 298 8.6E-90 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 HRM2_RS17370 e3fd3d8ce08e5e7750cc545d93e64820 298 Gene3D G3DSA:1.10.287.80 19 60 4.8E-23 T 22-04-2016 HRM2_RS17370 e3fd3d8ce08e5e7750cc545d93e64820 298 Gene3D G3DSA:1.10.287.80 212 246 4.8E-23 T 22-04-2016 HRM2_RS17370 e3fd3d8ce08e5e7750cc545d93e64820 298 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 297 30.353 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 HRM2_RS17370 e3fd3d8ce08e5e7750cc545d93e64820 298 Gene3D G3DSA:1.10.287.80 247 292 8.9E-22 T 22-04-2016 HRM2_RS17370 e3fd3d8ce08e5e7750cc545d93e64820 298 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 297 6.1E-81 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 HRM2_RS17370 e3fd3d8ce08e5e7750cc545d93e64820 298 Gene3D G3DSA:3.40.1380.10 65 192 1.8E-35 T 22-04-2016 HRM2_RS17370 e3fd3d8ce08e5e7750cc545d93e64820 298 Pfam PF00231 ATP synthase 3 297 3.1E-82 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 HRM2_RS17370 e3fd3d8ce08e5e7750cc545d93e64820 298 PRINTS PR00126 ATP synthase gamma subunit signature 275 296 8.5E-30 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 HRM2_RS17370 e3fd3d8ce08e5e7750cc545d93e64820 298 PRINTS PR00126 ATP synthase gamma subunit signature 167 184 8.5E-30 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 HRM2_RS17370 e3fd3d8ce08e5e7750cc545d93e64820 298 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 8.5E-30 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 HRM2_RS17370 e3fd3d8ce08e5e7750cc545d93e64820 298 PRINTS PR00126 ATP synthase gamma subunit signature 244 263 8.5E-30 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 HRM2_RS21820 6579e719cff653c1af7ef4c8379ed4cd 217 PANTHER PTHR18901:SF14 2 217 5.2E-36 T 22-04-2016 HRM2_RS21820 6579e719cff653c1af7ef4c8379ed4cd 217 SUPERFAMILY SSF56784 2 216 9.19E-50 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS21820 6579e719cff653c1af7ef4c8379ed4cd 217 Gene3D G3DSA:1.10.150.240 19 77 4.7E-14 T 22-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 HRM2_RS21820 6579e719cff653c1af7ef4c8379ed4cd 217 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 182 2.4E-32 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS21820 6579e719cff653c1af7ef4c8379ed4cd 217 Gene3D G3DSA:3.40.50.1000 78 216 4.5E-32 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS21820 6579e719cff653c1af7ef4c8379ed4cd 217 PANTHER PTHR18901 2 217 5.2E-36 T 22-04-2016 HRM2_RS13340 fb3f86211f4e14b9fc8ac12ded841eb2 252 PANTHER PTHR24220:SF66 8 238 3.7E-85 T 22-04-2016 HRM2_RS13340 fb3f86211f4e14b9fc8ac12ded841eb2 252 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS13340 fb3f86211f4e14b9fc8ac12ded841eb2 252 SMART SM00382 32 216 5.6E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS13340 fb3f86211f4e14b9fc8ac12ded841eb2 252 PANTHER PTHR24220 8 238 3.7E-85 T 22-04-2016 HRM2_RS13340 fb3f86211f4e14b9fc8ac12ded841eb2 252 Gene3D G3DSA:3.40.50.300 2 229 1.5E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13340 fb3f86211f4e14b9fc8ac12ded841eb2 252 SUPERFAMILY SSF52540 5 232 6.21E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13340 fb3f86211f4e14b9fc8ac12ded841eb2 252 Pfam PF00005 ABC transporter 24 167 6.1E-27 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS11945 0c13fec1e6bc02c6443280f2b824719b 322 Pfam PF00140 Sigma-70 factor, region 1.2 41 72 9.1E-12 T 22-04-2016 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS11945 0c13fec1e6bc02c6443280f2b824719b 322 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 105 118 - T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS11945 0c13fec1e6bc02c6443280f2b824719b 322 SUPERFAMILY SSF88659 215 313 1.13E-17 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS11945 0c13fec1e6bc02c6443280f2b824719b 322 Pfam PF04542 Sigma-70 region 2 80 150 2.0E-12 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS11945 0c13fec1e6bc02c6443280f2b824719b 322 Gene3D G3DSA:1.10.601.10 31 150 7.9E-39 T 22-04-2016 HRM2_RS11945 0c13fec1e6bc02c6443280f2b824719b 322 SUPERFAMILY SSF88946 39 150 5.02E-36 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS11945 0c13fec1e6bc02c6443280f2b824719b 322 PRINTS PR00046 Major sigma-70 factor signature 277 292 2.2E-22 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS11945 0c13fec1e6bc02c6443280f2b824719b 322 PRINTS PR00046 Major sigma-70 factor signature 258 270 2.2E-22 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS11945 0c13fec1e6bc02c6443280f2b824719b 322 PRINTS PR00046 Major sigma-70 factor signature 129 137 2.2E-22 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS11945 0c13fec1e6bc02c6443280f2b824719b 322 PRINTS PR00046 Major sigma-70 factor signature 105 118 2.2E-22 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS11945 0c13fec1e6bc02c6443280f2b824719b 322 PRINTS PR00046 Major sigma-70 factor signature 292 303 2.2E-22 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS11945 0c13fec1e6bc02c6443280f2b824719b 322 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 79 306 2.7E-26 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS11945 0c13fec1e6bc02c6443280f2b824719b 322 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 277 303 - T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS11945 0c13fec1e6bc02c6443280f2b824719b 322 PANTHER PTHR30376 30 307 2.8E-71 T 22-04-2016 HRM2_RS11945 0c13fec1e6bc02c6443280f2b824719b 322 Pfam PF04545 Sigma-70, region 4 256 305 1.4E-16 T 22-04-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS11945 0c13fec1e6bc02c6443280f2b824719b 322 Gene3D G3DSA:1.10.10.10 251 309 6.1E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS17445 1803f31f31b616cea9fec3af557135c8 160 Gene3D G3DSA:2.60.120.10 7 138 5.1E-24 T 22-04-2016 IPR014710 RmlC-like jelly roll fold HRM2_RS17445 1803f31f31b616cea9fec3af557135c8 160 SUPERFAMILY SSF51206 5 139 1.27E-25 T 22-04-2016 IPR018490 Cyclic nucleotide-binding-like HRM2_RS17445 1803f31f31b616cea9fec3af557135c8 160 SMART SM00100 12 130 6.8E-8 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain HRM2_RS17445 1803f31f31b616cea9fec3af557135c8 160 PANTHER PTHR24567 1 145 6.5E-18 T 22-04-2016 HRM2_RS17445 1803f31f31b616cea9fec3af557135c8 160 Pfam PF00027 Cyclic nucleotide-binding domain 32 118 5.9E-16 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain HRM2_RS03990 95be629e5dad43b07b7e1aa58a1953d2 444 Pfam PF00155 Aminotransferase class I and II 64 429 3.9E-17 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HRM2_RS03990 95be629e5dad43b07b7e1aa58a1953d2 444 SUPERFAMILY SSF53383 27 439 1.46E-49 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS03990 95be629e5dad43b07b7e1aa58a1953d2 444 PANTHER PTHR11751 305 420 8.3E-150 T 22-04-2016 HRM2_RS03990 95be629e5dad43b07b7e1aa58a1953d2 444 PANTHER PTHR11751 26 281 8.3E-150 T 22-04-2016 HRM2_RS03990 95be629e5dad43b07b7e1aa58a1953d2 444 Gene3D G3DSA:3.40.640.10 84 329 3.1E-32 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS03990 95be629e5dad43b07b7e1aa58a1953d2 444 PANTHER PTHR11751:SF385 305 420 8.3E-150 T 22-04-2016 HRM2_RS03990 95be629e5dad43b07b7e1aa58a1953d2 444 PANTHER PTHR11751:SF385 26 281 8.3E-150 T 22-04-2016 HRM2_RS07105 43a62b1a121c81f2e0cd88e4dfddea89 324 Pfam PF06463 Molybdenum Cofactor Synthesis C 181 306 7.3E-33 T 22-04-2016 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 HRM2_RS07105 43a62b1a121c81f2e0cd88e4dfddea89 324 SMART SM00729 9 233 1.1E-13 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS07105 43a62b1a121c81f2e0cd88e4dfddea89 324 SUPERFAMILY SSF102114 2 276 2.09E-75 T 22-04-2016 HRM2_RS07105 43a62b1a121c81f2e0cd88e4dfddea89 324 Gene3D G3DSA:3.20.20.70 2 304 8.8E-78 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS07105 43a62b1a121c81f2e0cd88e4dfddea89 324 Pfam PF13394 4Fe-4S single cluster domain 16 104 2.5E-8 T 22-04-2016 HRM2_RS07105 43a62b1a121c81f2e0cd88e4dfddea89 324 PANTHER PTHR22960 2 277 9.9E-121 T 22-04-2016 HRM2_RS07105 43a62b1a121c81f2e0cd88e4dfddea89 324 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 15 26 - T 22-04-2016 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 HRM2_RS07105 43a62b1a121c81f2e0cd88e4dfddea89 324 Hamap MF_01225_B Cyclic pyranopterin monophosphate synthase [moaA]. 1 324 36.659 T 22-04-2016 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 HRM2_RS07105 43a62b1a121c81f2e0cd88e4dfddea89 324 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 1 324 1.5E-108 T 22-04-2016 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 HRM2_RS07105 43a62b1a121c81f2e0cd88e4dfddea89 324 Pfam PF04055 Radical SAM superfamily 13 174 3.1E-33 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS15370 fe3620c63533486a92359fb4b0007c63 615 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 4 31 7.9E-6 T 22-04-2016 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria HRM2_RS15370 fe3620c63533486a92359fb4b0007c63 615 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 159 266 2.0E-15 T 22-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 HRM2_RS15370 fe3620c63533486a92359fb4b0007c63 615 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 281 450 9.8E-21 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS15370 fe3620c63533486a92359fb4b0007c63 615 SUPERFAMILY SSF56645 35 266 9.56E-50 T 22-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 HRM2_RS15370 fe3620c63533486a92359fb4b0007c63 615 PANTHER PTHR10909:SF296 9 475 3.3E-152 T 22-04-2016 HRM2_RS15370 fe3620c63533486a92359fb4b0007c63 615 Gene3D G3DSA:1.10.540.10 38 155 1.0E-14 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS15370 fe3620c63533486a92359fb4b0007c63 615 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 466 608 2.6E-29 T 22-04-2016 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain HRM2_RS15370 fe3620c63533486a92359fb4b0007c63 615 Gene3D G3DSA:1.20.140.10 264 459 1.7E-46 T 22-04-2016 HRM2_RS15370 fe3620c63533486a92359fb4b0007c63 615 PANTHER PTHR10909 9 475 3.3E-152 T 22-04-2016 HRM2_RS15370 fe3620c63533486a92359fb4b0007c63 615 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 38 154 7.4E-10 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS15370 fe3620c63533486a92359fb4b0007c63 615 Gene3D G3DSA:2.40.110.10 158 263 2.1E-21 T 22-04-2016 HRM2_RS15370 fe3620c63533486a92359fb4b0007c63 615 SUPERFAMILY SSF47203 287 473 5.64E-43 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS25370 7137634c2a8fb6d77e8cb9786cbd37b3 347 Gene3D G3DSA:2.40.440.10 55 186 1.3E-12 T 22-04-2016 HRM2_RS25370 7137634c2a8fb6d77e8cb9786cbd37b3 347 PANTHER PTHR36699 48 314 3.3E-16 T 22-04-2016 HRM2_RS25370 7137634c2a8fb6d77e8cb9786cbd37b3 347 SUPERFAMILY SSF141523 56 181 1.57E-12 T 22-04-2016 HRM2_RS25370 7137634c2a8fb6d77e8cb9786cbd37b3 347 Pfam PF03734 L,D-transpeptidase catalytic domain 56 185 5.8E-19 T 22-04-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UniPathway: UPA00219 HRM2_RS15035 ba2f1c13e7897cbf3159674b450ef2da 131 SUPERFAMILY SSF54211 6 131 1.74E-45 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS15035 ba2f1c13e7897cbf3159674b450ef2da 131 Gene3D G3DSA:3.30.230.10 5 131 2.5E-48 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HRM2_RS15035 ba2f1c13e7897cbf3159674b450ef2da 131 ProSitePatterns PS00360 Ribosomal protein S9 signature. 70 88 - T 22-04-2016 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 HRM2_RS15035 ba2f1c13e7897cbf3159674b450ef2da 131 PANTHER PTHR21569 1 131 5.7E-65 T 22-04-2016 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 HRM2_RS15035 ba2f1c13e7897cbf3159674b450ef2da 131 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 2 131 30.209 T 22-04-2016 IPR023035 Ribosomal protein S9, bacterial/plastid HRM2_RS15035 ba2f1c13e7897cbf3159674b450ef2da 131 Pfam PF00380 Ribosomal protein S9/S16 11 131 7.6E-46 T 22-04-2016 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 HRM2_RS10680 6e2a1bb465a272ce90136612d4032794 236 Pfam PF07722 Peptidase C26 3 214 9.2E-57 T 22-04-2016 IPR011697 Peptidase C26 GO:0006541|GO:0016787 HRM2_RS10680 6e2a1bb465a272ce90136612d4032794 236 PANTHER PTHR11922 27 235 3.3E-47 T 22-04-2016 HRM2_RS10680 6e2a1bb465a272ce90136612d4032794 236 Gene3D G3DSA:3.40.50.880 1 235 1.2E-48 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS10680 6e2a1bb465a272ce90136612d4032794 236 PANTHER PTHR11922:SF18 27 235 3.3E-47 T 22-04-2016 HRM2_RS10680 6e2a1bb465a272ce90136612d4032794 236 SUPERFAMILY SSF52317 22 234 9.57E-39 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS09905 5469ed43113a974cd937b4c11946a5c7 390 Pfam PF00534 Glycosyl transferases group 1 201 360 1.1E-31 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 HRM2_RS09905 5469ed43113a974cd937b4c11946a5c7 390 Gene3D G3DSA:3.40.50.2000 174 351 1.1E-29 T 22-04-2016 HRM2_RS09905 5469ed43113a974cd937b4c11946a5c7 390 PANTHER PTHR12526 87 383 3.5E-50 T 22-04-2016 HRM2_RS09905 5469ed43113a974cd937b4c11946a5c7 390 SUPERFAMILY SSF53756 59 383 5.65E-69 T 22-04-2016 HRM2_RS09905 5469ed43113a974cd937b4c11946a5c7 390 Pfam PF13439 Glycosyltransferase Family 4 76 190 5.1E-16 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain HRM2_RS18130 dcbe8f52ce2620fbb3426bcdbc3b0cfa 349 SUPERFAMILY SSF51269 287 348 4.08E-16 T 22-04-2016 IPR006190 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal HRM2_RS18130 dcbe8f52ce2620fbb3426bcdbc3b0cfa 349 Pfam PF03102 NeuB family 38 276 5.9E-95 T 22-04-2016 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 HRM2_RS18130 dcbe8f52ce2620fbb3426bcdbc3b0cfa 349 TIGRFAM TIGR03586 PseI: pseudaminic acid synthase 18 343 5.0E-154 T 22-04-2016 IPR020030 Pseudaminic acid biosynthesis, PseI KEGG: 00520+2.5.1.97|MetaCyc: PWY-6143 HRM2_RS18130 dcbe8f52ce2620fbb3426bcdbc3b0cfa 349 SUPERFAMILY SSF51569 5 301 1.47E-94 T 22-04-2016 HRM2_RS18130 dcbe8f52ce2620fbb3426bcdbc3b0cfa 349 SMART SM00858 291 349 7.1E-8 T 22-04-2016 IPR013974 SAF domain HRM2_RS18130 dcbe8f52ce2620fbb3426bcdbc3b0cfa 349 PANTHER PTHR23416:SF62 4 301 2.3E-117 T 22-04-2016 HRM2_RS18130 dcbe8f52ce2620fbb3426bcdbc3b0cfa 349 Gene3D G3DSA:3.20.20.70 5 275 3.2E-113 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS18130 dcbe8f52ce2620fbb3426bcdbc3b0cfa 349 Pfam PF08666 SAF domain 292 346 3.9E-9 T 22-04-2016 IPR013974 SAF domain HRM2_RS18130 dcbe8f52ce2620fbb3426bcdbc3b0cfa 349 PANTHER PTHR23416 4 301 2.3E-117 T 22-04-2016 HRM2_RS18130 dcbe8f52ce2620fbb3426bcdbc3b0cfa 349 Gene3D G3DSA:3.90.1210.10 292 348 1.4E-22 T 22-04-2016 IPR006190 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal HRM2_RS16345 dffe6d811fa93a9c838564ab1bb679c7 88 SUPERFAMILY SSF57716 38 72 3.56E-7 T 22-04-2016 HRM2_RS16345 dffe6d811fa93a9c838564ab1bb679c7 88 PANTHER PTHR38777:SF1 2 88 1.6E-25 T 22-04-2016 HRM2_RS16345 dffe6d811fa93a9c838564ab1bb679c7 88 PANTHER PTHR38777 2 88 1.6E-25 T 22-04-2016 HRM2_RS16345 dffe6d811fa93a9c838564ab1bb679c7 88 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 36 68 4.5E-10 T 22-04-2016 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 HRM2_RS13780 0b72c6f43f5a41ea19a5b07097e0940d 201 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 18 186 6.7E-18 T 22-04-2016 IPR010664 Lipopolysaccharide assembly, LptC-related HRM2_RS13780 0b72c6f43f5a41ea19a5b07097e0940d 201 Gene3D G3DSA:2.60.450.10 98 184 1.9E-8 T 22-04-2016 HRM2_RS13780 0b72c6f43f5a41ea19a5b07097e0940d 201 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 14 187 9.6E-25 T 22-04-2016 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 HRM2_RS13360 fff4e58c7828cb01331e652a5da4b0be 309 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 18 308 5.7E-86 T 22-04-2016 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00276|UniPathway: UPA00277 HRM2_RS13360 fff4e58c7828cb01331e652a5da4b0be 309 SUPERFAMILY SSF52374 15 177 3.1E-33 T 22-04-2016 HRM2_RS13360 fff4e58c7828cb01331e652a5da4b0be 309 Gene3D G3DSA:2.40.30.30 182 309 3.2E-43 T 22-04-2016 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 HRM2_RS13360 fff4e58c7828cb01331e652a5da4b0be 309 PANTHER PTHR22749:SF0 1 308 1.5E-120 T 22-04-2016 HRM2_RS13360 fff4e58c7828cb01331e652a5da4b0be 309 Gene3D G3DSA:3.40.50.620 1 181 2.1E-60 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS13360 fff4e58c7828cb01331e652a5da4b0be 309 SUPERFAMILY SSF82114 176 309 2.83E-45 T 22-04-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 HRM2_RS13360 fff4e58c7828cb01331e652a5da4b0be 309 Pfam PF01687 Riboflavin kinase 186 308 7.8E-39 T 22-04-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 HRM2_RS13360 fff4e58c7828cb01331e652a5da4b0be 309 PIRSF PIRSF004491 1 309 1.1E-105 T 22-04-2016 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00276|UniPathway: UPA00277 HRM2_RS13360 fff4e58c7828cb01331e652a5da4b0be 309 SMART SM00904 185 309 9.2E-57 T 22-04-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 HRM2_RS13360 fff4e58c7828cb01331e652a5da4b0be 309 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 18 80 3.1E-9 T 22-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HRM2_RS13360 fff4e58c7828cb01331e652a5da4b0be 309 PANTHER PTHR22749 1 308 1.5E-120 T 22-04-2016 IPR023468 Riboflavin kinase KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|UniPathway: UPA00276 HRM2_RS13360 fff4e58c7828cb01331e652a5da4b0be 309 Pfam PF06574 FAD synthetase 15 169 1.4E-51 T 22-04-2016 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00276|UniPathway: UPA00277 HRM2_RS01490 85cec3e37dc5b55d7da2ed1482a11e12 355 SUPERFAMILY SSF56112 17 344 2.91E-57 T 22-04-2016 IPR011009 Protein kinase-like domain HRM2_RS01490 85cec3e37dc5b55d7da2ed1482a11e12 355 Gene3D G3DSA:3.90.1200.10 133 333 1.0E-35 T 22-04-2016 HRM2_RS01490 85cec3e37dc5b55d7da2ed1482a11e12 355 Pfam PF01636 Phosphotransferase enzyme family 37 265 4.0E-43 T 22-04-2016 IPR002575 Aminoglycoside phosphotransferase HRM2_RS01490 85cec3e37dc5b55d7da2ed1482a11e12 355 PANTHER PTHR21310:SF14 16 265 6.2E-16 T 22-04-2016 HRM2_RS01490 85cec3e37dc5b55d7da2ed1482a11e12 355 PANTHER PTHR21310 16 265 6.2E-16 T 22-04-2016 HRM2_RS25515 feb6cdff1a2d3083dc3a9b9e36401413 143 PANTHER PTHR33221:SF6 2 137 3.5E-14 T 22-04-2016 HRM2_RS25515 feb6cdff1a2d3083dc3a9b9e36401413 143 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 48 66 - T 22-04-2016 IPR030489 Transcription regulator Rrf2-type, conserved site HRM2_RS25515 feb6cdff1a2d3083dc3a9b9e36401413 143 PANTHER PTHR33221 2 137 3.5E-14 T 22-04-2016 HRM2_RS25515 feb6cdff1a2d3083dc3a9b9e36401413 143 Gene3D G3DSA:1.10.10.10 1 139 1.6E-26 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS25515 feb6cdff1a2d3083dc3a9b9e36401413 143 SUPERFAMILY SSF46785 4 137 5.53E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS25515 feb6cdff1a2d3083dc3a9b9e36401413 143 Pfam PF02082 Transcriptional regulator 1 81 3.1E-17 T 22-04-2016 IPR000944 Transcription regulator Rrf2-type HRM2_RS15165 d4811c0b242d239c5c5ce8b4a2aa798a 649 Pfam PF14574 Domain of unknown function (DUF4445) 216 624 1.1E-139 T 22-04-2016 IPR027980 Protein of unknown function DUF4445 HRM2_RS15165 d4811c0b242d239c5c5ce8b4a2aa798a 649 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 11 81 1.4E-12 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 HRM2_RS15165 d4811c0b242d239c5c5ce8b4a2aa798a 649 SUPERFAMILY SSF54292 3 90 2.49E-23 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 HRM2_RS15165 d4811c0b242d239c5c5ce8b4a2aa798a 649 Gene3D G3DSA:3.10.20.30 3 95 2.6E-21 T 22-04-2016 IPR012675 Beta-grasp domain HRM2_RS15165 d4811c0b242d239c5c5ce8b4a2aa798a 649 SUPERFAMILY SSF53067 216 245 2.59E-5 T 22-04-2016 HRM2_RS15165 d4811c0b242d239c5c5ce8b4a2aa798a 649 SUPERFAMILY SSF53067 361 407 2.59E-5 T 22-04-2016 HRM2_RS15165 d4811c0b242d239c5c5ce8b4a2aa798a 649 SUPERFAMILY SSF53067 272 315 2.59E-5 T 22-04-2016 HRM2_RS15165 d4811c0b242d239c5c5ce8b4a2aa798a 649 SUPERFAMILY SSF53067 503 553 2.59E-5 T 22-04-2016 HRM2_RS15505 fa4fb198e3049da2fbccbd645b91b134 370 SUPERFAMILY SSF51713 1 368 1.83E-153 T 22-04-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 HRM2_RS15505 fa4fb198e3049da2fbccbd645b91b134 370 Pfam PF01702 Queuine tRNA-ribosyltransferase 130 364 4.9E-85 T 22-04-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 HRM2_RS15505 fa4fb198e3049da2fbccbd645b91b134 370 PANTHER PTHR21148 1 370 9.5E-162 T 22-04-2016 HRM2_RS15505 fa4fb198e3049da2fbccbd645b91b134 370 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 12 369 1.7E-161 T 22-04-2016 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 HRM2_RS15505 fa4fb198e3049da2fbccbd645b91b134 370 PANTHER PTHR21148:SF26 1 370 9.5E-162 T 22-04-2016 HRM2_RS15505 fa4fb198e3049da2fbccbd645b91b134 370 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 2 362 55.527 T 22-04-2016 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 HRM2_RS15505 fa4fb198e3049da2fbccbd645b91b134 370 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 12 369 6.5E-155 T 22-04-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 HRM2_RS15505 fa4fb198e3049da2fbccbd645b91b134 370 Gene3D G3DSA:3.20.20.105 1 368 6.9E-156 T 22-04-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 HRM2_RS06595 61f21795b093d82c550d366a811dcd35 399 PANTHER PTHR31970 11 399 1.1E-75 T 22-04-2016 HRM2_RS06595 61f21795b093d82c550d366a811dcd35 399 Pfam PF16983 Molybdate transporter of MFS superfamily 231 350 5.7E-28 T 22-04-2016 IPR031563 Molybdate transporter 1/2 GO:0015098|GO:0015689 HRM2_RS06595 61f21795b093d82c550d366a811dcd35 399 Pfam PF16983 Molybdate transporter of MFS superfamily 11 124 1.9E-31 T 22-04-2016 IPR031563 Molybdate transporter 1/2 GO:0015098|GO:0015689 HRM2_RS18765 ef42f06be24bf6be9e886accd8a9a5e4 198 PANTHER PTHR30086 1 198 7.8E-24 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 HRM2_RS18765 ef42f06be24bf6be9e886accd8a9a5e4 198 Pfam PF01810 LysE type translocator 15 194 2.8E-16 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 HRM2_RS18765 ef42f06be24bf6be9e886accd8a9a5e4 198 PANTHER PTHR30086:SF12 1 198 7.8E-24 T 22-04-2016 HRM2_RS09590 5291517d81d8f036721062a7ae8b1afb 103 Pfam PF08797 HIRAN domain 32 96 1.3E-7 T 22-04-2016 IPR014905 HIRAN domain GO:0003676|GO:0008270|GO:0016818 HRM2_RS25090 5c8e43599d045795e00d4a3d49eea0ca 248 TIGRFAM TIGR02681 phage_pRha: phage regulatory protein, Rha family 26 124 1.5E-28 T 22-04-2016 IPR014054 Bacteriophage regulatory protein, Rha family HRM2_RS25090 5c8e43599d045795e00d4a3d49eea0ca 248 Pfam PF09669 Phage regulatory protein Rha (Phage_pRha) 35 120 6.7E-25 T 22-04-2016 IPR014054 Bacteriophage regulatory protein, Rha family HRM2_RS11860 13bce13a3b7b246a47b609ccc2c6fdf5 562 Gene3D G3DSA:3.30.420.10 153 298 3.5E-5 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS23795 cb9f105dcbf328dd4047f7c49acea1d7 441 Gene3D G3DSA:3.80.30.20 145 377 3.4E-65 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe HRM2_RS23795 cb9f105dcbf328dd4047f7c49acea1d7 441 PANTHER PTHR11918 1 441 2.3E-162 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein HRM2_RS23795 cb9f105dcbf328dd4047f7c49acea1d7 441 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 438 7.4E-116 T 22-04-2016 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 HRM2_RS23795 cb9f105dcbf328dd4047f7c49acea1d7 441 Gene3D G3DSA:2.40.50.140 380 441 1.4E-21 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS23795 cb9f105dcbf328dd4047f7c49acea1d7 441 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 147 167 - T 22-04-2016 IPR020612 Methylthiotransferase, conserved site GO:0051539 HRM2_RS23795 cb9f105dcbf328dd4047f7c49acea1d7 441 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 1 440 57.845 T 22-04-2016 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 HRM2_RS23795 cb9f105dcbf328dd4047f7c49acea1d7 441 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 3 438 6.3E-135 T 22-04-2016 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 HRM2_RS23795 cb9f105dcbf328dd4047f7c49acea1d7 441 SUPERFAMILY SSF102114 134 370 2.35E-51 T 22-04-2016 HRM2_RS23795 cb9f105dcbf328dd4047f7c49acea1d7 441 Pfam PF00919 Uncharacterized protein family UPF0004 3 102 4.6E-24 T 22-04-2016 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 HRM2_RS23795 cb9f105dcbf328dd4047f7c49acea1d7 441 Pfam PF04055 Radical SAM superfamily 148 323 3.5E-22 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS23795 cb9f105dcbf328dd4047f7c49acea1d7 441 PANTHER PTHR11918:SF57 1 441 2.3E-162 T 22-04-2016 HRM2_RS23795 cb9f105dcbf328dd4047f7c49acea1d7 441 Pfam PF01938 TRAM domain 377 441 6.3E-9 T 22-04-2016 IPR002792 TRAM domain HRM2_RS23795 cb9f105dcbf328dd4047f7c49acea1d7 441 SMART SM00729 143 365 6.7E-44 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS24380 d9f0b46212b519d7cf4110f08b3db3eb 446 SUPERFAMILY SSF55073 268 438 8.63E-19 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS24380 d9f0b46212b519d7cf4110f08b3db3eb 446 Pfam PF00990 Diguanylate cyclase, GGDEF domain 267 365 2.2E-14 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS24380 d9f0b46212b519d7cf4110f08b3db3eb 446 Pfam PF00672 HAMP domain 189 256 9.9E-16 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS24380 d9f0b46212b519d7cf4110f08b3db3eb 446 SUPERFAMILY SSF158472 208 257 2.35E-7 T 22-04-2016 HRM2_RS24380 d9f0b46212b519d7cf4110f08b3db3eb 446 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 276 367 1.8E-14 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS24380 d9f0b46212b519d7cf4110f08b3db3eb 446 SMART SM00267 251 420 1.8E-6 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS24380 d9f0b46212b519d7cf4110f08b3db3eb 446 SMART SM00304 208 260 4.4E-10 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS24380 d9f0b46212b519d7cf4110f08b3db3eb 446 Gene3D G3DSA:3.30.70.270 267 409 1.4E-17 T 22-04-2016 HRM2_RS21565 bd8d245d38e738c14bc0fadbe8a69e66 353 PANTHER PTHR37560:SF2 10 353 1.0E-28 T 22-04-2016 HRM2_RS21565 bd8d245d38e738c14bc0fadbe8a69e66 353 Gene3D G3DSA:3.20.70.20 4 353 2.4E-87 T 22-04-2016 HRM2_RS21565 bd8d245d38e738c14bc0fadbe8a69e66 353 SUPERFAMILY SSF51998 3 353 1.37E-77 T 22-04-2016 HRM2_RS21565 bd8d245d38e738c14bc0fadbe8a69e66 353 PANTHER PTHR37560 10 353 1.0E-28 T 22-04-2016 HRM2_RS21565 bd8d245d38e738c14bc0fadbe8a69e66 353 Pfam PF05167 Uncharacterised ACR (DUF711) 6 353 6.7E-84 T 22-04-2016 IPR007841 Uncharacterised protein family UPF0210 HRM2_RS25680 df9764203286c1e3abe8df9b5e4d1bb9 148 PANTHER PTHR31964:SF45 1 145 3.7E-23 T 22-04-2016 HRM2_RS25680 df9764203286c1e3abe8df9b5e4d1bb9 148 SUPERFAMILY SSF52402 1 144 3.35E-29 T 22-04-2016 HRM2_RS25680 df9764203286c1e3abe8df9b5e4d1bb9 148 Gene3D G3DSA:3.40.50.620 1 144 8.1E-30 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS25680 df9764203286c1e3abe8df9b5e4d1bb9 148 Pfam PF00582 Universal stress protein family 1 144 5.1E-23 T 22-04-2016 IPR006016 UspA GO:0006950 HRM2_RS25680 df9764203286c1e3abe8df9b5e4d1bb9 148 PRINTS PR01438 Universal stress protein signature 2 20 9.1E-16 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS25680 df9764203286c1e3abe8df9b5e4d1bb9 148 PRINTS PR01438 Universal stress protein signature 122 144 9.1E-16 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS25680 df9764203286c1e3abe8df9b5e4d1bb9 148 PRINTS PR01438 Universal stress protein signature 104 116 9.1E-16 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS25680 df9764203286c1e3abe8df9b5e4d1bb9 148 PANTHER PTHR31964 1 145 3.7E-23 T 22-04-2016 HRM2_RS06840 007e167ea138085288c6db6f8cadef2d 257 Gene3D G3DSA:1.10.3720.10 1 254 8.5E-63 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS06840 007e167ea138085288c6db6f8cadef2d 257 SUPERFAMILY SSF161098 5 253 9.68E-57 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS06840 007e167ea138085288c6db6f8cadef2d 257 PANTHER PTHR30222:SF6 3 255 3.5E-106 T 22-04-2016 HRM2_RS06840 007e167ea138085288c6db6f8cadef2d 257 PANTHER PTHR30222 3 255 3.5E-106 T 22-04-2016 HRM2_RS06840 007e167ea138085288c6db6f8cadef2d 257 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 247 7.5E-16 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS12830 8f101e5ab0e1b455ed2d8883114d28b7 219 Gene3D G3DSA:1.20.950.20 4 164 8.1E-12 T 22-04-2016 HRM2_RS12830 8f101e5ab0e1b455ed2d8883114d28b7 219 Gene3D G3DSA:1.20.950.20 167 201 1.7E-5 T 22-04-2016 HRM2_RS12830 8f101e5ab0e1b455ed2d8883114d28b7 219 SUPERFAMILY SSF103501 1 27 3.4E-26 T 22-04-2016 IPR023234 NarG-like domain HRM2_RS12830 8f101e5ab0e1b455ed2d8883114d28b7 219 SUPERFAMILY SSF103501 62 201 3.4E-26 T 22-04-2016 IPR023234 NarG-like domain HRM2_RS15670 bc37fbb9dfe1d812c8dfd4f3f32ca19f 418 Gene3D G3DSA:3.40.309.10 228 374 2.1E-40 T 22-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 HRM2_RS15670 bc37fbb9dfe1d812c8dfd4f3f32ca19f 418 PANTHER PTHR11063:SF8 5 418 3.2E-176 T 22-04-2016 HRM2_RS15670 bc37fbb9dfe1d812c8dfd4f3f32ca19f 418 Pfam PF00171 Aldehyde dehydrogenase family 6 288 3.2E-16 T 22-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 HRM2_RS15670 bc37fbb9dfe1d812c8dfd4f3f32ca19f 418 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 6 417 40.115 T 22-04-2016 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 HRM2_RS15670 bc37fbb9dfe1d812c8dfd4f3f32ca19f 418 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 14 407 2.5E-143 T 22-04-2016 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 HRM2_RS15670 bc37fbb9dfe1d812c8dfd4f3f32ca19f 418 PANTHER PTHR11063 5 418 3.2E-176 T 22-04-2016 HRM2_RS15670 bc37fbb9dfe1d812c8dfd4f3f32ca19f 418 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 324 345 - T 22-04-2016 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 HRM2_RS15670 bc37fbb9dfe1d812c8dfd4f3f32ca19f 418 PIRSF PIRSF000151 1 418 1.3E-171 T 22-04-2016 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 HRM2_RS15670 bc37fbb9dfe1d812c8dfd4f3f32ca19f 418 Gene3D G3DSA:3.40.605.10 375 417 6.7E-101 T 22-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 HRM2_RS15670 bc37fbb9dfe1d812c8dfd4f3f32ca19f 418 Gene3D G3DSA:3.40.605.10 4 225 6.7E-101 T 22-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 HRM2_RS15670 bc37fbb9dfe1d812c8dfd4f3f32ca19f 418 SUPERFAMILY SSF53720 6 417 8.64E-112 T 22-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 HRM2_RS09160 6352253660aa07e567c81602a7337a69 266 Gene3D G3DSA:1.10.3720.10 6 253 6.6E-49 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS09160 6352253660aa07e567c81602a7337a69 266 PANTHER PTHR32243:SF18 5 266 3.5E-82 T 22-04-2016 HRM2_RS09160 6352253660aa07e567c81602a7337a69 266 SUPERFAMILY SSF161098 6 265 6.8E-56 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS09160 6352253660aa07e567c81602a7337a69 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 254 1.1E-5 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS09160 6352253660aa07e567c81602a7337a69 266 PANTHER PTHR32243 5 266 3.5E-82 T 22-04-2016 HRM2_RS20330 a4ad458c0b1e2bcd775c8f03cb2df6cf 173 SMART SM00100 26 143 3.5E-9 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain HRM2_RS20330 a4ad458c0b1e2bcd775c8f03cb2df6cf 173 SUPERFAMILY SSF51206 19 151 1.96E-26 T 22-04-2016 IPR018490 Cyclic nucleotide-binding-like HRM2_RS20330 a4ad458c0b1e2bcd775c8f03cb2df6cf 173 PANTHER PTHR24567 11 163 4.7E-14 T 22-04-2016 HRM2_RS20330 a4ad458c0b1e2bcd775c8f03cb2df6cf 173 PANTHER PTHR24567:SF30 11 163 4.7E-14 T 22-04-2016 HRM2_RS20330 a4ad458c0b1e2bcd775c8f03cb2df6cf 173 Pfam PF00027 Cyclic nucleotide-binding domain 45 130 2.8E-13 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain HRM2_RS20330 a4ad458c0b1e2bcd775c8f03cb2df6cf 173 Gene3D G3DSA:2.60.120.10 18 151 5.5E-25 T 22-04-2016 IPR014710 RmlC-like jelly roll fold HRM2_RS22950 739a50bebf2a71209b507edf322919a2 332 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 50 63 - T 22-04-2016 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 HRM2_RS22950 739a50bebf2a71209b507edf322919a2 332 SMART SM00062 27 256 1.4E-46 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS22950 739a50bebf2a71209b507edf322919a2 332 PANTHER PTHR30085:SF5 16 301 8.5E-131 T 22-04-2016 HRM2_RS22950 739a50bebf2a71209b507edf322919a2 332 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 28 246 3.6E-34 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS22950 739a50bebf2a71209b507edf322919a2 332 SUPERFAMILY SSF53850 18 247 8.54E-46 T 22-04-2016 HRM2_RS22950 739a50bebf2a71209b507edf322919a2 332 Gene3D G3DSA:3.40.190.10 217 246 3.4E-19 T 22-04-2016 HRM2_RS22950 739a50bebf2a71209b507edf322919a2 332 Gene3D G3DSA:3.40.190.10 25 111 3.4E-19 T 22-04-2016 HRM2_RS22950 739a50bebf2a71209b507edf322919a2 332 PANTHER PTHR30085 16 301 8.5E-131 T 22-04-2016 HRM2_RS22950 739a50bebf2a71209b507edf322919a2 332 Gene3D G3DSA:3.40.190.10 112 216 6.8E-15 T 22-04-2016 HRM2_RS08710 28c3417b9825d51965a244bb3629a335 848 SUPERFAMILY SSF51621 29 847 1.57E-201 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HRM2_RS08710 28c3417b9825d51965a244bb3629a335 848 Pfam PF00311 Phosphoenolpyruvate carboxylase 311 842 2.5E-112 T 22-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 HRM2_RS08710 28c3417b9825d51965a244bb3629a335 848 Pfam PF00311 Phosphoenolpyruvate carboxylase 139 285 5.1E-23 T 22-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 HRM2_RS08710 28c3417b9825d51965a244bb3629a335 848 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 183 199 1.0E-30 T 22-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 HRM2_RS08710 28c3417b9825d51965a244bb3629a335 848 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 681 707 1.0E-30 T 22-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 HRM2_RS08710 28c3417b9825d51965a244bb3629a335 848 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 505 525 1.0E-30 T 22-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 HRM2_RS08710 28c3417b9825d51965a244bb3629a335 848 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 142 155 1.0E-30 T 22-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 HRM2_RS08710 28c3417b9825d51965a244bb3629a335 848 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 547 576 1.0E-30 T 22-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 HRM2_RS08710 28c3417b9825d51965a244bb3629a335 848 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 238 253 1.0E-30 T 22-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 HRM2_RS08710 28c3417b9825d51965a244bb3629a335 848 PANTHER PTHR30523:SF0 131 848 1.0E-162 T 22-04-2016 HRM2_RS08710 28c3417b9825d51965a244bb3629a335 848 PANTHER PTHR30523 131 848 1.0E-162 T 22-04-2016 HRM2_RS16520 62abaae998328a3e306baebfdcef7ac2 218 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 83 217 1.1E-25 T 22-04-2016 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 HRM2_RS16520 62abaae998328a3e306baebfdcef7ac2 218 PANTHER PTHR11493 7 217 2.0E-71 T 22-04-2016 HRM2_RS16520 62abaae998328a3e306baebfdcef7ac2 218 PIRSF PIRSF037487 2 218 6.0E-95 T 22-04-2016 IPR017220 Sulphite reductase, assimilatory HRM2_RS16520 62abaae998328a3e306baebfdcef7ac2 218 SUPERFAMILY SSF56014 85 217 4.71E-42 T 22-04-2016 HRM2_RS16520 62abaae998328a3e306baebfdcef7ac2 218 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 10 74 1.2E-14 T 22-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 HRM2_RS16520 62abaae998328a3e306baebfdcef7ac2 218 Gene3D G3DSA:3.30.413.10 84 217 4.3E-38 T 22-04-2016 HRM2_RS16520 62abaae998328a3e306baebfdcef7ac2 218 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 130 146 - T 22-04-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 HRM2_RS16520 62abaae998328a3e306baebfdcef7ac2 218 SUPERFAMILY SSF55124 8 79 4.25E-17 T 22-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 HRM2_RS16520 62abaae998328a3e306baebfdcef7ac2 218 PRINTS PR00397 Sirohaem Fe-binding site signature 130 148 2.4E-7 T 22-04-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 HRM2_RS16520 62abaae998328a3e306baebfdcef7ac2 218 PRINTS PR00397 Sirohaem Fe-binding site signature 87 105 2.4E-7 T 22-04-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 HRM2_RS04370 d4489ec20cc0c8357eb98da1854e697a 1100 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 797 971 1.2E-4 T 22-04-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 HRM2_RS04370 d4489ec20cc0c8357eb98da1854e697a 1100 Gene3D G3DSA:3.40.50.300 255 360 1.9E-9 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04370 d4489ec20cc0c8357eb98da1854e697a 1100 Gene3D G3DSA:3.40.50.300 122 181 1.9E-9 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04370 d4489ec20cc0c8357eb98da1854e697a 1100 SMART SM00382 156 377 9.5 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS04370 d4489ec20cc0c8357eb98da1854e697a 1100 SMART SM00382 503 638 7.0E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS04370 d4489ec20cc0c8357eb98da1854e697a 1100 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 507 634 2.0E-18 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HRM2_RS04370 d4489ec20cc0c8357eb98da1854e697a 1100 Gene3D G3DSA:3.40.50.300 484 652 8.4E-25 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04370 d4489ec20cc0c8357eb98da1854e697a 1100 SUPERFAMILY SSF54211 809 986 1.06E-5 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS04370 d4489ec20cc0c8357eb98da1854e697a 1100 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 909 928 4.8E-7 T 22-04-2016 HRM2_RS04370 d4489ec20cc0c8357eb98da1854e697a 1100 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 809 825 4.8E-7 T 22-04-2016 HRM2_RS04370 d4489ec20cc0c8357eb98da1854e697a 1100 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 511 530 4.8E-7 T 22-04-2016 HRM2_RS04370 d4489ec20cc0c8357eb98da1854e697a 1100 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 968 986 4.8E-7 T 22-04-2016 HRM2_RS04370 d4489ec20cc0c8357eb98da1854e697a 1100 Gene3D G3DSA:3.30.230.10 805 1012 8.1E-19 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HRM2_RS04370 d4489ec20cc0c8357eb98da1854e697a 1100 ProSitePatterns PS00674 AAA-protein family signature. 610 628 - T 22-04-2016 IPR003960 ATPase, AAA-type, conserved site GO:0005524 HRM2_RS04370 d4489ec20cc0c8357eb98da1854e697a 1100 SUPERFAMILY SSF52540 490 709 4.78E-26 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04370 d4489ec20cc0c8357eb98da1854e697a 1100 PANTHER PTHR23077 499 632 1.9E-15 T 22-04-2016 HRM2_RS04370 d4489ec20cc0c8357eb98da1854e697a 1100 PANTHER PTHR23077:SF82 499 632 1.9E-15 T 22-04-2016 HRM2_RS04370 d4489ec20cc0c8357eb98da1854e697a 1100 SUPERFAMILY SSF52540 262 409 7.8E-11 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04370 d4489ec20cc0c8357eb98da1854e697a 1100 SUPERFAMILY SSF52540 132 186 7.8E-11 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09860 2084555284a8260337b35dbf0363f051 392 Gene3D G3DSA:3.30.470.20 214 321 8.1E-7 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS09860 2084555284a8260337b35dbf0363f051 392 Gene3D G3DSA:3.30.1490.20 108 201 1.5E-11 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HRM2_RS09860 2084555284a8260337b35dbf0363f051 392 SUPERFAMILY SSF56059 110 331 6.09E-18 T 22-04-2016 HRM2_RS06535 956aa1625935cf8d0c5920d9c2c19bde 149 PANTHER PTHR38009:SF1 3 148 6.1E-15 T 22-04-2016 HRM2_RS06535 956aa1625935cf8d0c5920d9c2c19bde 149 PANTHER PTHR38009 3 148 6.1E-15 T 22-04-2016 HRM2_RS06535 956aa1625935cf8d0c5920d9c2c19bde 149 Pfam PF06841 T4-like virus tail tube protein gp19 9 145 4.1E-43 T 22-04-2016 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 HRM2_RS06535 956aa1625935cf8d0c5920d9c2c19bde 149 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 5 146 1.7E-34 T 22-04-2016 IPR011747 Conserved hypothetical protein CHP02241 HRM2_RS18785 36ca3da15b1b54aefb0e5205a2d0cc4d 324 Gene3D G3DSA:3.40.190.10 21 104 1.8E-30 T 22-04-2016 HRM2_RS18785 36ca3da15b1b54aefb0e5205a2d0cc4d 324 Gene3D G3DSA:3.40.190.10 254 311 1.8E-30 T 22-04-2016 HRM2_RS18785 36ca3da15b1b54aefb0e5205a2d0cc4d 324 PANTHER PTHR30177:SF14 21 305 1.2E-49 T 22-04-2016 HRM2_RS18785 36ca3da15b1b54aefb0e5205a2d0cc4d 324 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 22 301 1.3E-59 T 22-04-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 HRM2_RS18785 36ca3da15b1b54aefb0e5205a2d0cc4d 324 Gene3D G3DSA:3.40.190.100 106 253 5.3E-43 T 22-04-2016 HRM2_RS18785 36ca3da15b1b54aefb0e5205a2d0cc4d 324 SUPERFAMILY SSF53850 19 317 9.5E-71 T 22-04-2016 HRM2_RS18785 36ca3da15b1b54aefb0e5205a2d0cc4d 324 PANTHER PTHR30177 21 305 1.2E-49 T 22-04-2016 HRM2_RS14865 2f70f583a5305109f15a9e8e1c8e4fd1 474 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 366 465 3.0E-15 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS14865 2f70f583a5305109f15a9e8e1c8e4fd1 474 SMART SM00388 254 319 4.0E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS14865 2f70f583a5305109f15a9e8e1c8e4fd1 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 426 5.7E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS14865 2f70f583a5305109f15a9e8e1c8e4fd1 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 445 5.7E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS14865 2f70f583a5305109f15a9e8e1c8e4fd1 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 451 464 5.7E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS14865 2f70f583a5305109f15a9e8e1c8e4fd1 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 412 5.7E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS14865 2f70f583a5305109f15a9e8e1c8e4fd1 474 Gene3D G3DSA:3.30.450.20 33 106 1.2E-4 T 22-04-2016 HRM2_RS14865 2f70f583a5305109f15a9e8e1c8e4fd1 474 Gene3D G3DSA:3.30.565.10 306 469 4.6E-35 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS14865 2f70f583a5305109f15a9e8e1c8e4fd1 474 SUPERFAMILY SSF55874 309 466 1.05E-34 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS14865 2f70f583a5305109f15a9e8e1c8e4fd1 474 SMART SM00304 185 237 8.0E-6 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS14865 2f70f583a5305109f15a9e8e1c8e4fd1 474 Pfam PF00512 His Kinase A (phospho-acceptor) domain 255 315 5.7E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS14865 2f70f583a5305109f15a9e8e1c8e4fd1 474 Gene3D G3DSA:1.10.287.130 250 305 5.2E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS14865 2f70f583a5305109f15a9e8e1c8e4fd1 474 SMART SM00387 361 467 9.5E-26 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS14865 2f70f583a5305109f15a9e8e1c8e4fd1 474 SUPERFAMILY SSF47384 249 315 7.85E-13 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS14865 2f70f583a5305109f15a9e8e1c8e4fd1 474 Pfam PF00672 HAMP domain 166 233 1.9E-11 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS14865 2f70f583a5305109f15a9e8e1c8e4fd1 474 PANTHER PTHR24423 250 470 3.0E-61 T 22-04-2016 HRM2_RS14865 2f70f583a5305109f15a9e8e1c8e4fd1 474 PANTHER PTHR24423 179 233 3.0E-61 T 22-04-2016 HRM2_RS14865 2f70f583a5305109f15a9e8e1c8e4fd1 474 PANTHER PTHR24423 30 47 3.0E-61 T 22-04-2016 HRM2_RS00605 6e8b4de86eeaa3a3ad0ea85a3ff7f01f 475 PIRSF PIRSF037567 2 475 1.6E-122 T 22-04-2016 IPR010426 Trimethylamine methyltransferase GO:0008168|GO:0015948 KEGG: 00680+2.1.1.250|MetaCyc: PWY-5250|UniPathway: UPA00645 HRM2_RS00605 6e8b4de86eeaa3a3ad0ea85a3ff7f01f 475 Pfam PF06253 Trimethylamine methyltransferase (MTTB) 6 472 2.1E-118 T 22-04-2016 IPR010426 Trimethylamine methyltransferase GO:0008168|GO:0015948 KEGG: 00680+2.1.1.250|MetaCyc: PWY-5250|UniPathway: UPA00645 HRM2_RS00225 6e8b4de86eeaa3a3ad0ea85a3ff7f01f 475 PIRSF PIRSF037567 2 475 1.6E-122 T 22-04-2016 IPR010426 Trimethylamine methyltransferase GO:0008168|GO:0015948 KEGG: 00680+2.1.1.250|MetaCyc: PWY-5250|UniPathway: UPA00645 HRM2_RS00225 6e8b4de86eeaa3a3ad0ea85a3ff7f01f 475 Pfam PF06253 Trimethylamine methyltransferase (MTTB) 6 472 2.1E-118 T 22-04-2016 IPR010426 Trimethylamine methyltransferase GO:0008168|GO:0015948 KEGG: 00680+2.1.1.250|MetaCyc: PWY-5250|UniPathway: UPA00645 HRM2_RS18095 c7dd3cba1ef3d473fcbea76da09e3729 482 PIRSF PIRSF006247 1 482 8.5E-179 T 22-04-2016 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 HRM2_RS18095 c7dd3cba1ef3d473fcbea76da09e3729 482 Pfam PF02386 Cation transport protein 46 476 8.0E-62 T 22-04-2016 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 HRM2_RS18095 c7dd3cba1ef3d473fcbea76da09e3729 482 PANTHER PTHR32024:SF2 1 482 2.8E-202 T 22-04-2016 HRM2_RS18095 c7dd3cba1ef3d473fcbea76da09e3729 482 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 85 465 7.3E-100 T 22-04-2016 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 HRM2_RS18095 c7dd3cba1ef3d473fcbea76da09e3729 482 PANTHER PTHR32024 1 482 2.8E-202 T 22-04-2016 HRM2_RS20290 c69b85cc6e0a07f2702256605ac3af58 385 Gene3D G3DSA:3.20.20.70 43 383 6.6E-68 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS20290 c69b85cc6e0a07f2702256605ac3af58 385 Gene3D G3DSA:2.20.28.10 1 29 4.8E-6 T 22-04-2016 IPR004039 Rubredoxin-type fold HRM2_RS20290 c69b85cc6e0a07f2702256605ac3af58 385 SUPERFAMILY SSF51395 84 384 4.32E-52 T 22-04-2016 HRM2_RS20290 c69b85cc6e0a07f2702256605ac3af58 385 Pfam PF01070 FMN-dependent dehydrogenase 84 223 5.1E-10 T 22-04-2016 IPR000262 FMN-dependent dehydrogenase GO:0016491 HRM2_RS20290 c69b85cc6e0a07f2702256605ac3af58 385 Pfam PF01070 FMN-dependent dehydrogenase 241 383 3.1E-43 T 22-04-2016 IPR000262 FMN-dependent dehydrogenase GO:0016491 HRM2_RS20290 c69b85cc6e0a07f2702256605ac3af58 385 PANTHER PTHR10578:SF65 84 385 2.3E-43 T 22-04-2016 HRM2_RS20290 c69b85cc6e0a07f2702256605ac3af58 385 PANTHER PTHR10578 84 385 2.3E-43 T 22-04-2016 HRM2_RS11780 485ca934e9c920ed1a0b8ce7b4548258 171 PANTHER PTHR33531:SF3 12 164 5.1E-12 T 22-04-2016 HRM2_RS11780 485ca934e9c920ed1a0b8ce7b4548258 171 Gene3D G3DSA:1.20.1260.10 9 153 6.7E-29 T 22-04-2016 IPR012347 Ferritin-related HRM2_RS11780 485ca934e9c920ed1a0b8ce7b4548258 171 SUPERFAMILY SSF47240 10 155 1.58E-24 T 22-04-2016 IPR009078 Ferritin-like superfamily HRM2_RS11780 485ca934e9c920ed1a0b8ce7b4548258 171 Pfam PF02915 Rubrerythrin 12 153 6.0E-13 T 22-04-2016 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 HRM2_RS11780 485ca934e9c920ed1a0b8ce7b4548258 171 PANTHER PTHR33531 12 164 5.1E-12 T 22-04-2016 HRM2_RS07080 2d8550d09e56234066011f5a0da20c22 344 PANTHER PTHR11695 12 339 1.4E-78 T 22-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 HRM2_RS07080 2d8550d09e56234066011f5a0da20c22 344 SUPERFAMILY SSF50129 1 173 1.83E-44 T 22-04-2016 IPR011032 GroES-like HRM2_RS07080 2d8550d09e56234066011f5a0da20c22 344 PANTHER PTHR11695:SF38 12 339 1.4E-78 T 22-04-2016 HRM2_RS07080 2d8550d09e56234066011f5a0da20c22 344 SMART SM00829 8 340 2.9E-8 T 22-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 HRM2_RS07080 2d8550d09e56234066011f5a0da20c22 344 Gene3D G3DSA:3.40.50.720 166 283 6.4E-29 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS07080 2d8550d09e56234066011f5a0da20c22 344 SUPERFAMILY SSF51735 140 309 9.38E-33 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS07080 2d8550d09e56234066011f5a0da20c22 344 Gene3D G3DSA:3.90.180.10 1 165 3.1E-48 T 22-04-2016 IPR011032 GroES-like HRM2_RS07080 2d8550d09e56234066011f5a0da20c22 344 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 131 7.1E-24 T 22-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 HRM2_RS07080 2d8550d09e56234066011f5a0da20c22 344 Pfam PF00107 Zinc-binding dehydrogenase 174 302 1.2E-16 T 22-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 HRM2_RS16055 ade10012049c50d492f80d1d5a7a3a0d 249 SUPERFAMILY SSF56300 1 245 1.13E-46 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS16055 ade10012049c50d492f80d1d5a7a3a0d 249 PANTHER PTHR11124:SF2 186 248 9.8E-34 T 22-04-2016 HRM2_RS16055 ade10012049c50d492f80d1d5a7a3a0d 249 PANTHER PTHR11124:SF2 107 166 9.8E-34 T 22-04-2016 HRM2_RS16055 ade10012049c50d492f80d1d5a7a3a0d 249 PANTHER PTHR11124:SF2 1 77 9.8E-34 T 22-04-2016 HRM2_RS16055 ade10012049c50d492f80d1d5a7a3a0d 249 PANTHER PTHR11124 186 248 9.8E-34 T 22-04-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 HRM2_RS16055 ade10012049c50d492f80d1d5a7a3a0d 249 PANTHER PTHR11124 107 166 9.8E-34 T 22-04-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 HRM2_RS16055 ade10012049c50d492f80d1d5a7a3a0d 249 PANTHER PTHR11124 1 77 9.8E-34 T 22-04-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 HRM2_RS16055 ade10012049c50d492f80d1d5a7a3a0d 249 PIRSF PIRSF000883 1 249 4.0E-41 T 22-04-2016 IPR011152 Phosphoesterase MJ0912 HRM2_RS16055 ade10012049c50d492f80d1d5a7a3a0d 249 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 213 1.2E-21 T 22-04-2016 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type HRM2_RS16055 ade10012049c50d492f80d1d5a7a3a0d 249 Gene3D G3DSA:3.60.21.10 1 246 1.2E-55 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS18225 136ac8f61653ec32b97a55176edae8c9 81 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 49 6.0E-5 T 22-04-2016 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 HRM2_RS18225 136ac8f61653ec32b97a55176edae8c9 81 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 56 5.9E-24 T 22-04-2016 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 HRM2_RS18225 136ac8f61653ec32b97a55176edae8c9 81 PANTHER PTHR34984:SF1 1 81 2.1E-21 T 22-04-2016 HRM2_RS18225 136ac8f61653ec32b97a55176edae8c9 81 Hamap MF_00167 Carbon storage regulator [csrA]. 1 70 18.669 T 22-04-2016 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 HRM2_RS18225 136ac8f61653ec32b97a55176edae8c9 81 PANTHER PTHR34984 1 81 2.1E-21 T 22-04-2016 HRM2_RS18225 136ac8f61653ec32b97a55176edae8c9 81 SUPERFAMILY SSF117130 1 55 4.45E-19 T 22-04-2016 HRM2_RS18225 136ac8f61653ec32b97a55176edae8c9 81 Pfam PF02599 Global regulator protein family 1 52 1.5E-23 T 22-04-2016 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 HRM2_RS20880 8994a61043831447dbfbc67d8a2b0cef 85 Pfam PF08679 Dissimilatory sulfite reductase D (DsrD) 12 75 7.0E-33 T 22-04-2016 IPR014793 Dissimilatory sulphite reductase D HRM2_RS20880 8994a61043831447dbfbc67d8a2b0cef 85 SUPERFAMILY SSF46785 9 80 1.95E-27 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS20880 8994a61043831447dbfbc67d8a2b0cef 85 Gene3D G3DSA:1.10.10.10 9 85 2.3E-36 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS09140 13941abd0dba3467b1a634e3f6fee217 505 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 3 501 1.8E-219 T 22-04-2016 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 HRM2_RS09140 13941abd0dba3467b1a634e3f6fee217 505 Gene3D G3DSA:3.30.420.40 2 257 9.5E-101 T 22-04-2016 HRM2_RS09140 13941abd0dba3467b1a634e3f6fee217 505 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 134 146 - T 22-04-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 HRM2_RS09140 13941abd0dba3467b1a634e3f6fee217 505 SUPERFAMILY SSF53067 4 259 1.62E-85 T 22-04-2016 HRM2_RS09140 13941abd0dba3467b1a634e3f6fee217 505 SUPERFAMILY SSF53067 259 502 8.81E-84 T 22-04-2016 HRM2_RS09140 13941abd0dba3467b1a634e3f6fee217 505 PIRSF PIRSF000538 2 505 1.1E-160 T 22-04-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 HRM2_RS09140 13941abd0dba3467b1a634e3f6fee217 505 Gene3D G3DSA:3.30.420.40 259 503 6.2E-102 T 22-04-2016 HRM2_RS09140 13941abd0dba3467b1a634e3f6fee217 505 PANTHER PTHR10196:SF69 1 503 4.3E-266 T 22-04-2016 HRM2_RS09140 13941abd0dba3467b1a634e3f6fee217 505 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 256 4.6E-75 T 22-04-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 HRM2_RS09140 13941abd0dba3467b1a634e3f6fee217 505 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 367 387 - T 22-04-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 HRM2_RS09140 13941abd0dba3467b1a634e3f6fee217 505 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 265 455 2.2E-65 T 22-04-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 HRM2_RS09140 13941abd0dba3467b1a634e3f6fee217 505 Hamap MF_00186 Glycerol kinase [glpK]. 2 502 53.99 T 22-04-2016 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 HRM2_RS09140 13941abd0dba3467b1a634e3f6fee217 505 PANTHER PTHR10196 1 503 4.3E-266 T 22-04-2016 HRM2_RS00380 286c45085081613e77ea5a43abebc977 215 PANTHER PTHR10681 4 211 8.8E-63 T 22-04-2016 HRM2_RS00380 286c45085081613e77ea5a43abebc977 215 PIRSF PIRSF000239 3 214 5.1E-72 T 22-04-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15 HRM2_RS00380 286c45085081613e77ea5a43abebc977 215 Gene3D G3DSA:3.40.30.10 10 160 3.1E-51 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS00380 286c45085081613e77ea5a43abebc977 215 Hamap MF_00401 Peroxiredoxin. 8 214 48.499 T 22-04-2016 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 HRM2_RS00380 286c45085081613e77ea5a43abebc977 215 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 160 198 7.1E-10 T 22-04-2016 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 HRM2_RS00380 286c45085081613e77ea5a43abebc977 215 Gene3D G3DSA:3.30.1020.10 161 214 5.2E-19 T 22-04-2016 HRM2_RS00380 286c45085081613e77ea5a43abebc977 215 Pfam PF00578 AhpC/TSA family 11 138 6.2E-26 T 22-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 HRM2_RS00380 286c45085081613e77ea5a43abebc977 215 SUPERFAMILY SSF52833 6 214 4.29E-62 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS22140 7bbbe7ab5f3a10acab848dfa6839f70a 160 Pfam PF05433 Glycine zipper 2TM domain 68 107 9.2E-7 T 22-04-2016 IPR008816 Glycine zipper 2TM domain GO:0019867 HRM2_RS22140 7bbbe7ab5f3a10acab848dfa6839f70a 160 PANTHER PTHR35603 9 159 8.2E-32 T 22-04-2016 HRM2_RS16150 7fafaf41e516f6b1190a8eaa0af07f9d 97 Pfam PF01206 Sulfurtransferase TusA 15 88 4.5E-9 T 22-04-2016 IPR001455 TusA-like domain HRM2_RS16150 7fafaf41e516f6b1190a8eaa0af07f9d 97 SUPERFAMILY SSF64307 11 74 5.49E-9 T 22-04-2016 IPR001455 TusA-like domain HRM2_RS16150 7fafaf41e516f6b1190a8eaa0af07f9d 97 Gene3D G3DSA:3.30.110.40 7 88 5.7E-12 T 22-04-2016 IPR001455 TusA-like domain HRM2_RS08365 aaf5a90ddc9aab6c5a343cd13efaa76a 175 SMART SM01058 17 128 3.6E-29 T 22-04-2016 IPR003711 CarD-like/TRCF domain HRM2_RS08365 aaf5a90ddc9aab6c5a343cd13efaa76a 175 PANTHER PTHR38447 17 172 6.1E-41 T 22-04-2016 HRM2_RS08365 aaf5a90ddc9aab6c5a343cd13efaa76a 175 SUPERFAMILY SSF141259 16 82 3.4E-14 T 22-04-2016 IPR003711 CarD-like/TRCF domain HRM2_RS08365 aaf5a90ddc9aab6c5a343cd13efaa76a 175 Pfam PF02559 CarD-like/TRCF domain 20 126 2.7E-15 T 22-04-2016 IPR003711 CarD-like/TRCF domain HRM2_RS11345 0e5cfa6ceae143307fa5e77d7aafa620 269 PANTHER PTHR30221 5 265 3.8E-104 T 22-04-2016 HRM2_RS11345 0e5cfa6ceae143307fa5e77d7aafa620 269 Gene3D G3DSA:3.30.70.100 170 254 2.4E-34 T 22-04-2016 HRM2_RS11345 0e5cfa6ceae143307fa5e77d7aafa620 269 Pfam PF05552 Conserved TM helix 9 52 2.2E-9 T 22-04-2016 IPR008910 Conserved TM helix HRM2_RS11345 0e5cfa6ceae143307fa5e77d7aafa620 269 Pfam PF00924 Mechanosensitive ion channel 60 256 2.5E-59 T 22-04-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 HRM2_RS11345 0e5cfa6ceae143307fa5e77d7aafa620 269 SUPERFAMILY SSF82689 170 267 1.07E-36 T 22-04-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 HRM2_RS11345 0e5cfa6ceae143307fa5e77d7aafa620 269 SUPERFAMILY SSF82861 16 100 8.89E-19 T 22-04-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 HRM2_RS11345 0e5cfa6ceae143307fa5e77d7aafa620 269 Gene3D G3DSA:2.30.30.60 117 166 9.0E-20 T 22-04-2016 HRM2_RS11345 0e5cfa6ceae143307fa5e77d7aafa620 269 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 131 165 - T 22-04-2016 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 HRM2_RS11345 0e5cfa6ceae143307fa5e77d7aafa620 269 PANTHER PTHR30221:SF7 5 265 3.8E-104 T 22-04-2016 HRM2_RS11345 0e5cfa6ceae143307fa5e77d7aafa620 269 SUPERFAMILY SSF50182 102 167 3.6E-19 T 22-04-2016 IPR010920 LSM domain HRM2_RS11625 dc17b75f0ed8c548b86a99e2bb92aed2 225 PANTHER PTHR31223:SF1 13 219 1.4E-93 T 22-04-2016 HRM2_RS11625 dc17b75f0ed8c548b86a99e2bb92aed2 225 SUPERFAMILY SSF102405 13 216 3.05E-63 T 22-04-2016 HRM2_RS11625 dc17b75f0ed8c548b86a99e2bb92aed2 225 Pfam PF03641 Possible lysine decarboxylase 86 215 2.2E-36 T 22-04-2016 IPR031100 LOG family HRM2_RS11625 dc17b75f0ed8c548b86a99e2bb92aed2 225 PANTHER PTHR31223 13 219 1.4E-93 T 22-04-2016 HRM2_RS11625 dc17b75f0ed8c548b86a99e2bb92aed2 225 Gene3D G3DSA:3.40.50.450 29 224 2.6E-66 T 22-04-2016 HRM2_RS11625 dc17b75f0ed8c548b86a99e2bb92aed2 225 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 44 219 7.5E-50 T 22-04-2016 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG HRM2_RS11030 e684272375c83ee08fd0650469d8f355 465 Pfam PF00535 Glycosyl transferase family 2 93 264 8.5E-30 T 22-04-2016 IPR001173 Glycosyltransferase 2-like HRM2_RS11030 e684272375c83ee08fd0650469d8f355 465 PANTHER PTHR22913 158 338 7.2E-44 T 22-04-2016 IPR026107 Hyaluronan synthase/nodulation protein C HRM2_RS11030 e684272375c83ee08fd0650469d8f355 465 Gene3D G3DSA:3.90.550.10 93 334 4.5E-32 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS11030 e684272375c83ee08fd0650469d8f355 465 SUPERFAMILY SSF53448 86 347 4.82E-46 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS11030 e684272375c83ee08fd0650469d8f355 465 PANTHER PTHR22913:SF12 158 338 7.2E-44 T 22-04-2016 HRM2_RS21470 fa50d9bf0635632b3a73803fe41815d3 819 PANTHER PTHR11468 7 811 0.0 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HRM2_RS21470 fa50d9bf0635632b3a73803fe41815d3 819 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 655 667 - T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HRM2_RS21470 fa50d9bf0635632b3a73803fe41815d3 819 SUPERFAMILY SSF53756 7 814 2.67E-302 T 22-04-2016 HRM2_RS21470 fa50d9bf0635632b3a73803fe41815d3 819 Gene3D G3DSA:3.40.50.2000 7 479 8.8E-201 T 22-04-2016 HRM2_RS21470 fa50d9bf0635632b3a73803fe41815d3 819 PIRSF PIRSF000460 1 817 1.3E-218 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HRM2_RS21470 fa50d9bf0635632b3a73803fe41815d3 819 PANTHER PTHR11468:SF3 7 811 0.0 T 22-04-2016 HRM2_RS21470 fa50d9bf0635632b3a73803fe41815d3 819 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 10 811 0.0 T 22-04-2016 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HRM2_RS21470 fa50d9bf0635632b3a73803fe41815d3 819 Gene3D G3DSA:3.40.50.2000 480 797 3.9E-126 T 22-04-2016 HRM2_RS21470 fa50d9bf0635632b3a73803fe41815d3 819 Pfam PF00343 Carbohydrate phosphorylase 98 811 0.0 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HRM2_RS02195 d7dc617234dca8142f03d7902e0ddc3c 260 PANTHER PTHR11941 2 249 2.8E-71 T 22-04-2016 HRM2_RS02195 d7dc617234dca8142f03d7902e0ddc3c 260 SUPERFAMILY SSF52096 1 252 1.46E-70 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS02195 d7dc617234dca8142f03d7902e0ddc3c 260 Gene3D G3DSA:3.90.226.10 1 252 1.6E-72 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS02195 d7dc617234dca8142f03d7902e0ddc3c 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 253 2.1E-53 T 22-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 HRM2_RS04585 9d260415796d6891f906b50bb33056a4 87 Gene3D G3DSA:3.30.2020.10 3 79 1.0E-18 T 22-04-2016 IPR018841 Protein of unknown function DUF2442 HRM2_RS04585 9d260415796d6891f906b50bb33056a4 87 SUPERFAMILY SSF143880 3 80 9.29E-22 T 22-04-2016 IPR018841 Protein of unknown function DUF2442 HRM2_RS04585 9d260415796d6891f906b50bb33056a4 87 Pfam PF10387 Protein of unknown function (DUF2442) 7 79 6.6E-21 T 22-04-2016 IPR018841 Protein of unknown function DUF2442 HRM2_RS10815 7ba9a60f7304cfc0292a48ee5bd02d5e 467 Pfam PF01926 50S ribosome-binding GTPase 9 78 2.7E-11 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS10815 7ba9a60f7304cfc0292a48ee5bd02d5e 467 SUPERFAMILY SSF52540 4 162 5.35E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10815 7ba9a60f7304cfc0292a48ee5bd02d5e 467 Gene3D G3DSA:3.40.50.300 6 169 5.2E-20 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10815 7ba9a60f7304cfc0292a48ee5bd02d5e 467 Pfam PF11981 Domain of unknown function (DUF3482) 165 452 1.3E-68 T 22-04-2016 IPR021871 Protein of unknown function DUF3482 HRM2_RS16020 063389bfa1655143e0aabc816901bde1 327 PANTHER PTHR23408 12 327 9.1E-150 T 22-04-2016 HRM2_RS16020 063389bfa1655143e0aabc816901bde1 327 Gene3D G3DSA:1.20.5.170 5 57 2.6E-18 T 22-04-2016 HRM2_RS16020 063389bfa1655143e0aabc816901bde1 327 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 19 323 1.6E-104 T 22-04-2016 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 HRM2_RS16020 063389bfa1655143e0aabc816901bde1 327 SUPERFAMILY SSF52540 7 325 1.33E-86 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16020 063389bfa1655143e0aabc816901bde1 327 Gene3D G3DSA:3.40.50.300 58 260 1.7E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16020 063389bfa1655143e0aabc816901bde1 327 PANTHER PTHR23408:SF17 12 327 9.1E-150 T 22-04-2016 HRM2_RS16020 063389bfa1655143e0aabc816901bde1 327 Pfam PF03308 ArgK protein 24 295 2.0E-105 T 22-04-2016 HRM2_RS16200 58597578879246e6e8a81b166b9c8bfe 66 SMART SM00357 3 66 5.5E-23 T 22-04-2016 IPR011129 Cold shock protein GO:0003676 HRM2_RS16200 58597578879246e6e8a81b166b9c8bfe 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.1E-24 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HRM2_RS16200 58597578879246e6e8a81b166b9c8bfe 66 PANTHER PTHR11544 1 66 9.0E-28 T 22-04-2016 HRM2_RS16200 58597578879246e6e8a81b166b9c8bfe 66 PRINTS PR00050 Cold shock protein signature 4 19 6.2E-15 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HRM2_RS16200 58597578879246e6e8a81b166b9c8bfe 66 PRINTS PR00050 Cold shock protein signature 39 57 6.2E-15 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HRM2_RS16200 58597578879246e6e8a81b166b9c8bfe 66 PRINTS PR00050 Cold shock protein signature 24 33 6.2E-15 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HRM2_RS16200 58597578879246e6e8a81b166b9c8bfe 66 SUPERFAMILY SSF50249 1 65 1.22E-21 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS16200 58597578879246e6e8a81b166b9c8bfe 66 PIRSF PIRSF002599 1 66 1.6E-20 T 22-04-2016 IPR012156 Cold shock, CspA GO:0003676 HRM2_RS16200 58597578879246e6e8a81b166b9c8bfe 66 Gene3D G3DSA:2.40.50.140 1 65 5.8E-27 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS05370 614ea04fb9f3f78a4f82f57d450bcc42 221 SUPERFAMILY SSF75615 113 210 2.09E-20 T 22-04-2016 HRM2_RS05370 614ea04fb9f3f78a4f82f57d450bcc42 221 Gene3D G3DSA:3.30.160.110 112 146 3.2E-15 T 22-04-2016 HRM2_RS05370 614ea04fb9f3f78a4f82f57d450bcc42 221 PANTHER PTHR35330 1 215 7.2E-50 T 22-04-2016 HRM2_RS05370 614ea04fb9f3f78a4f82f57d450bcc42 221 SUPERFAMILY SSF51735 1 111 7.88E-19 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS05370 614ea04fb9f3f78a4f82f57d450bcc42 221 Gene3D G3DSA:3.40.50.720 1 111 1.3E-33 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS05370 614ea04fb9f3f78a4f82f57d450bcc42 221 Pfam PF13241 Putative NAD(P)-binding 8 114 4.4E-30 T 22-04-2016 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 HRM2_RS05370 614ea04fb9f3f78a4f82f57d450bcc42 221 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 5 204 2.1E-39 T 22-04-2016 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 HRM2_RS05370 614ea04fb9f3f78a4f82f57d450bcc42 221 Pfam PF14824 Sirohaem biosynthesis protein central 118 143 8.4E-10 T 22-04-2016 IPR028281 Siroheme synthase, central domain KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 HRM2_RS16440 b0d6bb9a0e71b160195c4f1ec9c4cecf 332 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 29 305 4.6E-34 T 22-04-2016 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 HRM2_RS16440 b0d6bb9a0e71b160195c4f1ec9c4cecf 332 PANTHER PTHR33376 2 331 2.1E-39 T 22-04-2016 HRM2_RS08255 83c97a2a356bf299083c5c5095694c63 260 PANTHER PTHR13696:SF73 3 254 3.8E-69 T 22-04-2016 HRM2_RS08255 83c97a2a356bf299083c5c5095694c63 260 SUPERFAMILY SSF52540 4 256 3.55E-32 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08255 83c97a2a356bf299083c5c5095694c63 260 PIRSF PIRSF005647 3 258 2.9E-72 T 22-04-2016 IPR014433 Nickel insertion ATPase/GTPase (CO dehydrogenase maturation factor), CooC type HRM2_RS08255 83c97a2a356bf299083c5c5095694c63 260 Gene3D G3DSA:3.40.50.300 7 255 1.1E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08255 83c97a2a356bf299083c5c5095694c63 260 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 210 2.1E-26 T 22-04-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain HRM2_RS08255 83c97a2a356bf299083c5c5095694c63 260 PANTHER PTHR13696 3 254 3.8E-69 T 22-04-2016 HRM2_RS06875 9cec24e00acf61c70e931f3e568bf5d6 914 SUPERFAMILY SSF56059 66 238 1.94E-8 T 22-04-2016 HRM2_RS06875 9cec24e00acf61c70e931f3e568bf5d6 914 PANTHER PTHR34595 498 896 2.4E-227 T 22-04-2016 HRM2_RS06875 9cec24e00acf61c70e931f3e568bf5d6 914 PANTHER PTHR34595 57 481 2.4E-227 T 22-04-2016 HRM2_RS06875 9cec24e00acf61c70e931f3e568bf5d6 914 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 564 883 5.3E-71 T 22-04-2016 IPR007296 Domain of unknown function DUF403 HRM2_RS06875 9cec24e00acf61c70e931f3e568bf5d6 914 Pfam PF14403 Circularly permuted ATP-grasp type 2 120 516 3.4E-136 T 22-04-2016 IPR025841 Circularly permuted ATP-grasp type 2 HRM2_RS06875 9cec24e00acf61c70e931f3e568bf5d6 914 PANTHER PTHR34595:SF1 498 896 2.4E-227 T 22-04-2016 HRM2_RS06875 9cec24e00acf61c70e931f3e568bf5d6 914 PANTHER PTHR34595:SF1 57 481 2.4E-227 T 22-04-2016 HRM2_RS17760 f5d4ac5c11fd3e9f8b7f7c44359b8d78 513 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 6 243 8.6E-95 T 22-04-2016 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 HRM2_RS17760 f5d4ac5c11fd3e9f8b7f7c44359b8d78 513 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 7 219 1.8E-47 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 HRM2_RS17760 f5d4ac5c11fd3e9f8b7f7c44359b8d78 513 Pfam PF02602 Uroporphyrinogen-III synthase HemD 270 499 1.7E-63 T 22-04-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 HRM2_RS17760 f5d4ac5c11fd3e9f8b7f7c44359b8d78 513 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 11 25 - T 22-04-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 HRM2_RS17760 f5d4ac5c11fd3e9f8b7f7c44359b8d78 513 PANTHER PTHR21091 1 237 2.2E-84 T 22-04-2016 HRM2_RS17760 f5d4ac5c11fd3e9f8b7f7c44359b8d78 513 SUPERFAMILY SSF69618 256 508 7.85E-70 T 22-04-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 HRM2_RS17760 f5d4ac5c11fd3e9f8b7f7c44359b8d78 513 PANTHER PTHR21091:SF16 1 237 2.2E-84 T 22-04-2016 HRM2_RS17760 f5d4ac5c11fd3e9f8b7f7c44359b8d78 513 Gene3D G3DSA:3.40.1010.10 5 121 3.7E-43 T 22-04-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 HRM2_RS17760 f5d4ac5c11fd3e9f8b7f7c44359b8d78 513 Gene3D G3DSA:3.30.950.10 122 261 6.3E-57 T 22-04-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 HRM2_RS17760 f5d4ac5c11fd3e9f8b7f7c44359b8d78 513 Gene3D G3DSA:3.40.50.10090 262 377 3.1E-35 T 22-04-2016 HRM2_RS17760 f5d4ac5c11fd3e9f8b7f7c44359b8d78 513 Gene3D G3DSA:3.40.50.10090 381 509 2.9E-32 T 22-04-2016 HRM2_RS17760 f5d4ac5c11fd3e9f8b7f7c44359b8d78 513 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 86 119 - T 22-04-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 HRM2_RS17760 f5d4ac5c11fd3e9f8b7f7c44359b8d78 513 SUPERFAMILY SSF53790 2 259 9.16E-83 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 HRM2_RS11775 61eb4dc033495d932cf372be19d2fbe4 275 PANTHER PTHR23026 70 258 1.9E-31 T 22-04-2016 HRM2_RS11775 61eb4dc033495d932cf372be19d2fbe4 275 Pfam PF00881 Nitroreductase family 77 258 4.5E-25 T 22-04-2016 IPR029479 Nitroreductase HRM2_RS11775 61eb4dc033495d932cf372be19d2fbe4 275 Gene3D G3DSA:3.40.109.10 69 258 4.1E-27 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 HRM2_RS11775 61eb4dc033495d932cf372be19d2fbe4 275 SUPERFAMILY SSF55469 72 265 3.93E-28 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 HRM2_RS11775 61eb4dc033495d932cf372be19d2fbe4 275 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 92 258 8.0E-34 T 22-04-2016 IPR020051 SagB-type dehydrogenase domain HRM2_RS11775 61eb4dc033495d932cf372be19d2fbe4 275 PANTHER PTHR23026:SF61 70 258 1.9E-31 T 22-04-2016 HRM2_RS16815 bb9bb993c9eedca77e5f528ceeb1b161 380 Gene3D G3DSA:2.40.50.100 71 103 9.6E-14 T 22-04-2016 HRM2_RS16815 bb9bb993c9eedca77e5f528ceeb1b161 380 Gene3D G3DSA:2.40.50.100 178 207 9.6E-14 T 22-04-2016 HRM2_RS16815 bb9bb993c9eedca77e5f528ceeb1b161 380 PANTHER PTHR30469:SF10 4 371 6.2E-68 T 22-04-2016 HRM2_RS16815 bb9bb993c9eedca77e5f528ceeb1b161 380 PANTHER PTHR30469 4 371 6.2E-68 T 22-04-2016 HRM2_RS16815 bb9bb993c9eedca77e5f528ceeb1b161 380 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 45 370 8.8E-67 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 HRM2_RS16815 bb9bb993c9eedca77e5f528ceeb1b161 380 SUPERFAMILY SSF111369 59 289 3.53E-23 T 22-04-2016 HRM2_RS16815 bb9bb993c9eedca77e5f528ceeb1b161 380 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 61 287 1.1E-14 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain HRM2_RS10790 54983f7ff9aa262ddae308518a76ae65 184 Gene3D G3DSA:3.30.70.260 1 78 2.3E-19 T 22-04-2016 HRM2_RS10790 54983f7ff9aa262ddae308518a76ae65 184 Gene3D G3DSA:3.30.70.260 93 183 6.1E-18 T 22-04-2016 HRM2_RS10790 54983f7ff9aa262ddae308518a76ae65 184 SUPERFAMILY SSF55021 3 80 2.8E-13 T 22-04-2016 HRM2_RS10790 54983f7ff9aa262ddae308518a76ae65 184 SUPERFAMILY SSF55021 95 178 3.31E-11 T 22-04-2016 HRM2_RS10790 54983f7ff9aa262ddae308518a76ae65 184 Pfam PF13740 ACT domain 95 172 2.7E-8 T 22-04-2016 HRM2_RS10790 54983f7ff9aa262ddae308518a76ae65 184 Pfam PF13740 ACT domain 4 76 4.9E-11 T 22-04-2016 HRM2_RS10790 54983f7ff9aa262ddae308518a76ae65 184 PANTHER PTHR34875 1 182 7.8E-19 T 22-04-2016 HRM2_RS02255 e4f691059b04ba2ea3adf1e96c3da253 181 Gene3D G3DSA:3.40.140.10 4 157 2.8E-35 T 22-04-2016 HRM2_RS02255 e4f691059b04ba2ea3adf1e96c3da253 181 PANTHER PTHR11079 10 119 6.2E-24 T 22-04-2016 HRM2_RS02255 e4f691059b04ba2ea3adf1e96c3da253 181 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 63 100 - T 22-04-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 HRM2_RS02255 e4f691059b04ba2ea3adf1e96c3da253 181 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 10 111 1.1E-20 T 22-04-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 HRM2_RS02255 e4f691059b04ba2ea3adf1e96c3da253 181 SUPERFAMILY SSF53927 6 160 6.91E-36 T 22-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 HRM2_RS03260 15921cfce5294273319b739a51be460c 459 Gene3D G3DSA:2.40.50.140 3 100 7.9E-16 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS03260 15921cfce5294273319b739a51be460c 459 Pfam PF01336 OB-fold nucleic acid binding domain 19 97 4.4E-8 T 22-04-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 HRM2_RS03260 15921cfce5294273319b739a51be460c 459 SUPERFAMILY SSF50249 5 99 1.74E-16 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS03260 15921cfce5294273319b739a51be460c 459 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 4 459 43.49 T 22-04-2016 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22|Reactome: REACT_71 HRM2_RS03260 15921cfce5294273319b739a51be460c 459 PRINTS PR01042 Aspartyl-tRNA synthetase signature 414 428 7.4E-13 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS03260 15921cfce5294273319b739a51be460c 459 PRINTS PR01042 Aspartyl-tRNA synthetase signature 201 213 7.4E-13 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS03260 15921cfce5294273319b739a51be460c 459 PRINTS PR01042 Aspartyl-tRNA synthetase signature 217 230 7.4E-13 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS03260 15921cfce5294273319b739a51be460c 459 PRINTS PR01042 Aspartyl-tRNA synthetase signature 374 390 7.4E-13 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS03260 15921cfce5294273319b739a51be460c 459 Gene3D G3DSA:3.30.930.10 104 456 6.9E-111 T 22-04-2016 HRM2_RS03260 15921cfce5294273319b739a51be460c 459 Pfam PF00152 tRNA synthetases class II (D, K and N) 114 453 6.0E-84 T 22-04-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS03260 15921cfce5294273319b739a51be460c 459 PANTHER PTHR22594 17 175 3.6E-226 T 22-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS03260 15921cfce5294273319b739a51be460c 459 PANTHER PTHR22594 192 458 3.6E-226 T 22-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS03260 15921cfce5294273319b739a51be460c 459 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 6 459 9.2E-178 T 22-04-2016 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22|Reactome: REACT_71 HRM2_RS03260 15921cfce5294273319b739a51be460c 459 PANTHER PTHR22594:SF6 17 175 3.6E-226 T 22-04-2016 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22|Reactome: REACT_71 HRM2_RS03260 15921cfce5294273319b739a51be460c 459 PANTHER PTHR22594:SF6 192 458 3.6E-226 T 22-04-2016 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22|Reactome: REACT_71 HRM2_RS03260 15921cfce5294273319b739a51be460c 459 SUPERFAMILY SSF55681 100 457 1.18E-92 T 22-04-2016 HRM2_RS08070 2f4b589f1cea04b9946a573c71c009ab 867 SUPERFAMILY SSF52009 454 557 8.76E-18 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS08070 2f4b589f1cea04b9946a573c71c009ab 867 SUPERFAMILY SSF56059 127 431 1.88E-60 T 22-04-2016 HRM2_RS08070 2f4b589f1cea04b9946a573c71c009ab 867 PANTHER PTHR22931:SF7 132 560 3.5E-75 T 22-04-2016 HRM2_RS08070 2f4b589f1cea04b9946a573c71c009ab 867 Pfam PF00391 PEP-utilising enzyme, mobile domain 480 551 4.6E-13 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS08070 2f4b589f1cea04b9946a573c71c009ab 867 Gene3D G3DSA:3.30.470.20 301 431 2.8E-27 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS08070 2f4b589f1cea04b9946a573c71c009ab 867 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 130 431 9.9E-69 T 22-04-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 HRM2_RS08070 2f4b589f1cea04b9946a573c71c009ab 867 Gene3D G3DSA:3.30.1490.20 128 300 1.0E-46 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HRM2_RS08070 2f4b589f1cea04b9946a573c71c009ab 867 PANTHER PTHR22931 132 560 3.5E-75 T 22-04-2016 HRM2_RS08070 2f4b589f1cea04b9946a573c71c009ab 867 Gene3D G3DSA:3.50.30.10 473 560 2.6E-18 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS20520 68352adfa7ca6ce1b5fc5d2348bb877d 336 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 246 336 3.2E-17 T 22-04-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 HRM2_RS20520 68352adfa7ca6ce1b5fc5d2348bb877d 336 SUPERFAMILY SSF53901 8 335 3.13E-39 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS20520 68352adfa7ca6ce1b5fc5d2348bb877d 336 Gene3D G3DSA:3.40.47.10 165 336 2.6E-26 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS20520 68352adfa7ca6ce1b5fc5d2348bb877d 336 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 110 187 5.9E-13 T 22-04-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 HRM2_RS20520 68352adfa7ca6ce1b5fc5d2348bb877d 336 PANTHER PTHR34069 3 336 1.1E-55 T 22-04-2016 HRM2_RS20520 68352adfa7ca6ce1b5fc5d2348bb877d 336 Gene3D G3DSA:3.40.47.10 4 164 9.8E-37 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS04925 8f414795acbf2d245725bcb4e78f52f5 261 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 260 1.9E-69 T 22-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 HRM2_RS04925 8f414795acbf2d245725bcb4e78f52f5 261 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 102 122 - T 22-04-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 HRM2_RS04925 8f414795acbf2d245725bcb4e78f52f5 261 Gene3D G3DSA:3.90.226.10 6 200 2.9E-77 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS04925 8f414795acbf2d245725bcb4e78f52f5 261 Gene3D G3DSA:1.10.12.10 204 261 3.7E-21 T 22-04-2016 IPR014748 Crontonase, C-terminal HRM2_RS04925 8f414795acbf2d245725bcb4e78f52f5 261 SUPERFAMILY SSF52096 5 261 1.81E-89 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS04925 8f414795acbf2d245725bcb4e78f52f5 261 PANTHER PTHR11941 4 258 3.7E-125 T 22-04-2016 HRM2_RS04925 8f414795acbf2d245725bcb4e78f52f5 261 PANTHER PTHR11941:SF61 4 258 3.7E-125 T 22-04-2016 HRM2_RS17035 c4e6c80aab8f0b47c2c700ec3727ec6d 454 Pfam PF00072 Response regulator receiver domain 9 121 9.1E-26 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS17035 c4e6c80aab8f0b47c2c700ec3727ec6d 454 Gene3D G3DSA:3.40.50.2300 5 136 5.7E-35 T 22-04-2016 HRM2_RS17035 c4e6c80aab8f0b47c2c700ec3727ec6d 454 PANTHER PTHR26402 7 118 4.2E-34 T 22-04-2016 HRM2_RS17035 c4e6c80aab8f0b47c2c700ec3727ec6d 454 SUPERFAMILY SSF53850 144 374 1.0E-16 T 22-04-2016 HRM2_RS17035 c4e6c80aab8f0b47c2c700ec3727ec6d 454 Pfam PF13379 NMT1-like family 143 375 2.3E-25 T 22-04-2016 HRM2_RS17035 c4e6c80aab8f0b47c2c700ec3727ec6d 454 SUPERFAMILY SSF52172 6 126 1.1E-33 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS17035 c4e6c80aab8f0b47c2c700ec3727ec6d 454 SMART SM00448 7 121 5.7E-33 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS10885 b00dadbb65966eab93b78ca0b78c561b 250 Gene3D G3DSA:3.40.50.300 4 234 1.8E-72 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10885 b00dadbb65966eab93b78ca0b78c561b 250 SMART SM00382 30 219 2.0E-14 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS10885 b00dadbb65966eab93b78ca0b78c561b 250 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS10885 b00dadbb65966eab93b78ca0b78c561b 250 PANTHER PTHR24220 7 244 1.1E-98 T 22-04-2016 HRM2_RS10885 b00dadbb65966eab93b78ca0b78c561b 250 SUPERFAMILY SSF52540 6 234 4.75E-65 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10885 b00dadbb65966eab93b78ca0b78c561b 250 PANTHER PTHR24220:SF567 7 244 1.1E-98 T 22-04-2016 HRM2_RS10885 b00dadbb65966eab93b78ca0b78c561b 250 Pfam PF00005 ABC transporter 22 169 3.6E-33 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS12940 c5e7e734505ed516c75808740a21c784 328 SUPERFAMILY SSF55895 118 301 6.93E-30 T 22-04-2016 IPR001568 Ribonuclease T2-like GO:0003723|GO:0033897 HRM2_RS12940 c5e7e734505ed516c75808740a21c784 328 Gene3D G3DSA:3.90.730.10 119 320 4.5E-33 T 22-04-2016 IPR001568 Ribonuclease T2-like GO:0003723|GO:0033897 HRM2_RS12940 c5e7e734505ed516c75808740a21c784 328 Pfam PF00445 Ribonuclease T2 family 120 284 2.7E-18 T 22-04-2016 IPR001568 Ribonuclease T2-like GO:0003723|GO:0033897 HRM2_RS12940 c5e7e734505ed516c75808740a21c784 328 ProSitePatterns PS00530 Ribonuclease T2 family histidine active site 1. 152 159 - T 22-04-2016 IPR018188 Ribonuclease T2, His active site 1 GO:0003723|GO:0033897 HRM2_RS12445 999357905e5f4e3869d5751bab73ab8d 237 SMART SM00382 27 216 4.7E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS12445 999357905e5f4e3869d5751bab73ab8d 237 Gene3D G3DSA:3.40.50.300 3 233 7.9E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12445 999357905e5f4e3869d5751bab73ab8d 237 PANTHER PTHR24220:SF568 4 236 5.2E-112 T 22-04-2016 HRM2_RS12445 999357905e5f4e3869d5751bab73ab8d 237 Pfam PF00005 ABC transporter 18 165 6.6E-26 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS12445 999357905e5f4e3869d5751bab73ab8d 237 PANTHER PTHR24220 4 236 5.2E-112 T 22-04-2016 HRM2_RS12445 999357905e5f4e3869d5751bab73ab8d 237 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS12445 999357905e5f4e3869d5751bab73ab8d 237 SUPERFAMILY SSF52540 3 235 3.4E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21870 65eb9b2584bced6915f1bf4c2696eb53 562 Gene3D G3DSA:3.30.420.10 154 298 4.3E-5 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS16955 65eb9b2584bced6915f1bf4c2696eb53 562 Gene3D G3DSA:3.30.420.10 154 298 4.3E-5 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS03915 65eb9b2584bced6915f1bf4c2696eb53 562 Gene3D G3DSA:3.30.420.10 154 298 4.3E-5 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS10255 65eb9b2584bced6915f1bf4c2696eb53 562 Gene3D G3DSA:3.30.420.10 154 298 4.3E-5 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS03595 65eb9b2584bced6915f1bf4c2696eb53 562 Gene3D G3DSA:3.30.420.10 154 298 4.3E-5 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS06180 5feaad56a9afa22c199e66710ca7a369 334 PANTHER PTHR10289 1 332 3.1E-153 T 22-04-2016 HRM2_RS06180 5feaad56a9afa22c199e66710ca7a369 334 PIRSF PIRSF017617 1 334 4.2E-133 T 22-04-2016 IPR023603 Threonine aldolase HRM2_RS06180 5feaad56a9afa22c199e66710ca7a369 334 Gene3D G3DSA:3.90.1150.10 246 333 6.8E-23 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS06180 5feaad56a9afa22c199e66710ca7a369 334 PANTHER PTHR10289:SF5 1 332 3.1E-153 T 22-04-2016 HRM2_RS06180 5feaad56a9afa22c199e66710ca7a369 334 SUPERFAMILY SSF53383 1 333 4.08E-114 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS06180 5feaad56a9afa22c199e66710ca7a369 334 Gene3D G3DSA:3.40.640.10 1 245 4.4E-88 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS06180 5feaad56a9afa22c199e66710ca7a369 334 Pfam PF01212 Beta-eliminating lyase 3 284 7.4E-94 T 22-04-2016 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 HRM2_RS22890 ed21acf33180dd1b7ba8a3fc26b6b9ac 183 SUPERFAMILY SSF46894 111 170 3.74E-15 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HRM2_RS22890 ed21acf33180dd1b7ba8a3fc26b6b9ac 183 Gene3D G3DSA:1.10.10.10 123 170 1.6E-15 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS22890 ed21acf33180dd1b7ba8a3fc26b6b9ac 183 SMART SM00421 120 177 1.8E-12 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS22890 ed21acf33180dd1b7ba8a3fc26b6b9ac 183 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 137 153 2.3E-10 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS22890 ed21acf33180dd1b7ba8a3fc26b6b9ac 183 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 123 137 2.3E-10 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS22890 ed21acf33180dd1b7ba8a3fc26b6b9ac 183 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 165 2.3E-10 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS22890 ed21acf33180dd1b7ba8a3fc26b6b9ac 183 ProSitePatterns PS00622 LuxR-type HTH domain signature. 137 164 - T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS22890 ed21acf33180dd1b7ba8a3fc26b6b9ac 183 Pfam PF00196 Bacterial regulatory proteins, luxR family 122 169 1.4E-14 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HRM2_RS10165 27b453aa0220ac062b08e914721a091c 466 Pfam PF04851 Type III restriction enzyme, res subunit 108 246 4.1E-19 T 22-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HRM2_RS10165 27b453aa0220ac062b08e914721a091c 466 Pfam PF00271 Helicase conserved C-terminal domain 331 422 2.5E-11 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS10165 27b453aa0220ac062b08e914721a091c 466 PANTHER PTHR11274 107 250 1.7E-26 T 22-04-2016 HRM2_RS10165 27b453aa0220ac062b08e914721a091c 466 SUPERFAMILY SSF52540 147 267 2.16E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10165 27b453aa0220ac062b08e914721a091c 466 SUPERFAMILY SSF52540 313 440 2.16E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10165 27b453aa0220ac062b08e914721a091c 466 Gene3D G3DSA:3.40.50.300 331 433 2.9E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10165 27b453aa0220ac062b08e914721a091c 466 Gene3D G3DSA:3.40.50.300 103 263 1.7E-35 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10165 27b453aa0220ac062b08e914721a091c 466 SMART SM00487 104 276 2.6E-25 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS10165 27b453aa0220ac062b08e914721a091c 466 SMART SM00490 337 424 4.5E-8 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS01390 866625399a4a9385e2fbb5359e9421f3 307 SUPERFAMILY SSF56281 9 254 1.44E-34 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS01390 866625399a4a9385e2fbb5359e9421f3 307 Pfam PF00753 Metallo-beta-lactamase superfamily 27 225 1.4E-15 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS01390 866625399a4a9385e2fbb5359e9421f3 307 SMART SM00849 27 212 1.0E-23 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS01390 866625399a4a9385e2fbb5359e9421f3 307 PANTHER PTHR11935 15 174 5.3E-16 T 22-04-2016 HRM2_RS01390 866625399a4a9385e2fbb5359e9421f3 307 Gene3D G3DSA:3.60.15.10 7 242 1.2E-27 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS17745 8395b76ad3b82614da1b4904f4bca520 189 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 1 186 34.207 T 22-04-2016 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478|UniPathway: UPA00041 HRM2_RS17745 8395b76ad3b82614da1b4904f4bca520 189 PANTHER PTHR30390:SF6 1 187 1.7E-78 T 22-04-2016 HRM2_RS17745 8395b76ad3b82614da1b4904f4bca520 189 PANTHER PTHR30390 1 187 1.7E-78 T 22-04-2016 HRM2_RS17745 8395b76ad3b82614da1b4904f4bca520 189 SUPERFAMILY SSF53697 2 187 1.42E-49 T 22-04-2016 HRM2_RS17745 8395b76ad3b82614da1b4904f4bca520 189 Gene3D G3DSA:3.40.50.10490 1 187 9.9E-57 T 22-04-2016 HRM2_RS17745 8395b76ad3b82614da1b4904f4bca520 189 Pfam PF13580 SIS domain 15 144 3.2E-31 T 22-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 HRM2_RS00305 d4f0fdd3e872807b22411c0615eef60b 188 Pfam PF02613 Nitrate reductase delta subunit 43 134 1.8E-7 T 22-04-2016 IPR020945 DMSO/Nitrate reductase chaperone HRM2_RS00305 d4f0fdd3e872807b22411c0615eef60b 188 PANTHER PTHR30598 8 168 1.2E-21 T 22-04-2016 HRM2_RS00305 d4f0fdd3e872807b22411c0615eef60b 188 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 14 161 3.2E-25 T 22-04-2016 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 HRM2_RS00305 d4f0fdd3e872807b22411c0615eef60b 188 PANTHER PTHR30598:SF1 8 168 1.2E-21 T 22-04-2016 HRM2_RS00305 d4f0fdd3e872807b22411c0615eef60b 188 Gene3D G3DSA:1.10.3480.10 8 174 4.8E-7 T 22-04-2016 IPR020945 DMSO/Nitrate reductase chaperone HRM2_RS00305 d4f0fdd3e872807b22411c0615eef60b 188 SUPERFAMILY SSF89155 9 166 8.76E-24 T 22-04-2016 IPR020945 DMSO/Nitrate reductase chaperone HRM2_RS20035 4ec384e94abc6d2e09cb66c67fccf905 225 SUPERFAMILY SSF51206 7 146 8.38E-39 T 22-04-2016 IPR018490 Cyclic nucleotide-binding-like HRM2_RS20035 4ec384e94abc6d2e09cb66c67fccf905 225 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 188 203 3.1E-7 T 22-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HRM2_RS20035 4ec384e94abc6d2e09cb66c67fccf905 225 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 172 188 3.1E-7 T 22-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HRM2_RS20035 4ec384e94abc6d2e09cb66c67fccf905 225 SMART SM00419 166 214 2.5E-12 T 22-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HRM2_RS20035 4ec384e94abc6d2e09cb66c67fccf905 225 Pfam PF00027 Cyclic nucleotide-binding domain 31 118 1.2E-21 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain HRM2_RS20035 4ec384e94abc6d2e09cb66c67fccf905 225 Gene3D G3DSA:2.60.120.10 10 146 1.9E-39 T 22-04-2016 IPR014710 RmlC-like jelly roll fold HRM2_RS20035 4ec384e94abc6d2e09cb66c67fccf905 225 Pfam PF13545 Crp-like helix-turn-helix domain 151 221 2.1E-17 T 22-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HRM2_RS20035 4ec384e94abc6d2e09cb66c67fccf905 225 Gene3D G3DSA:1.10.10.10 149 223 4.1E-18 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS20035 4ec384e94abc6d2e09cb66c67fccf905 225 SUPERFAMILY SSF46785 149 223 1.33E-15 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS20035 4ec384e94abc6d2e09cb66c67fccf905 225 PANTHER PTHR24567 1 222 1.7E-55 T 22-04-2016 HRM2_RS20035 4ec384e94abc6d2e09cb66c67fccf905 225 SMART SM00100 13 134 9.8E-23 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain HRM2_RS15820 fbcd07751845eecc31eedf9ecdcdcdbc 151 Pfam PF04246 Positive regulator of sigma(E), RseC/MucC 8 140 8.8E-33 T 22-04-2016 IPR007359 Positive regulator of sigma(E), RseC/MucC HRM2_RS15820 fbcd07751845eecc31eedf9ecdcdcdbc 151 PANTHER PTHR35867:SF1 2 141 2.0E-20 T 22-04-2016 HRM2_RS15820 fbcd07751845eecc31eedf9ecdcdcdbc 151 PANTHER PTHR35867 2 141 2.0E-20 T 22-04-2016 HRM2_RS15820 fbcd07751845eecc31eedf9ecdcdcdbc 151 PIRSF PIRSF004923 1 149 4.4E-31 T 22-04-2016 IPR026268 Protein RseC HRM2_RS21490 9c8e2b7098df5328af0eb6e38b594927 377 Pfam PF00144 Beta-lactamase 12 347 1.9E-46 T 22-04-2016 IPR001466 Beta-lactamase-related HRM2_RS21490 9c8e2b7098df5328af0eb6e38b594927 377 PANTHER PTHR22935 1 342 1.2E-52 T 22-04-2016 HRM2_RS21490 9c8e2b7098df5328af0eb6e38b594927 377 SUPERFAMILY SSF56601 4 344 1.99E-67 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HRM2_RS21490 9c8e2b7098df5328af0eb6e38b594927 377 Gene3D G3DSA:3.40.710.10 5 349 1.4E-67 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HRM2_RS25195 6e04e405b8040858afcba1312a410577 215 Gene3D G3DSA:2.160.10.10 88 213 2.7E-34 T 22-04-2016 HRM2_RS25195 6e04e405b8040858afcba1312a410577 215 SUPERFAMILY SSF51161 101 213 5.63E-36 T 22-04-2016 IPR011004 Trimeric LpxA-like HRM2_RS25195 6e04e405b8040858afcba1312a410577 215 PANTHER PTHR23416 97 211 5.1E-26 T 22-04-2016 HRM2_RS25195 6e04e405b8040858afcba1312a410577 215 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 136 157 0.0012 T 22-04-2016 IPR001451 Hexapeptide repeat HRM2_RS25195 6e04e405b8040858afcba1312a410577 215 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 169 194 8.8E-5 T 22-04-2016 IPR001451 Hexapeptide repeat HRM2_RS25195 6e04e405b8040858afcba1312a410577 215 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 105 129 0.0012 T 22-04-2016 IPR001451 Hexapeptide repeat HRM2_RS25495 094ed6cd087fdd7546a4ba4179679769 334 Pfam PF02108 Flagellar assembly protein FliH 197 325 3.3E-16 T 22-04-2016 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE HRM2_RS25495 094ed6cd087fdd7546a4ba4179679769 334 PANTHER PTHR34982:SF1 125 332 2.6E-23 T 22-04-2016 HRM2_RS25495 094ed6cd087fdd7546a4ba4179679769 334 SUPERFAMILY SSF160527 229 330 6.8E-5 T 22-04-2016 HRM2_RS25495 094ed6cd087fdd7546a4ba4179679769 334 PANTHER PTHR34982 125 332 2.6E-23 T 22-04-2016 HRM2_RS10430 4dd4188e4200289a29a153c44212ed49 293 Gene3D G3DSA:3.40.190.10 85 197 1.4E-19 T 22-04-2016 HRM2_RS10430 4dd4188e4200289a29a153c44212ed49 293 PANTHER PTHR30126:SF14 1 287 3.8E-110 T 22-04-2016 HRM2_RS10430 4dd4188e4200289a29a153c44212ed49 293 Pfam PF03466 LysR substrate binding domain 88 290 1.9E-29 T 22-04-2016 IPR005119 LysR, substrate-binding HRM2_RS10430 4dd4188e4200289a29a153c44212ed49 293 Gene3D G3DSA:1.10.10.10 1 84 1.0E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS10430 4dd4188e4200289a29a153c44212ed49 293 SUPERFAMILY SSF46785 1 83 2.94E-16 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS10430 4dd4188e4200289a29a153c44212ed49 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.0E-13 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HRM2_RS10430 4dd4188e4200289a29a153c44212ed49 293 Gene3D G3DSA:3.40.190.10 198 248 2.5E-9 T 22-04-2016 HRM2_RS10430 4dd4188e4200289a29a153c44212ed49 293 PANTHER PTHR30126 1 287 3.8E-110 T 22-04-2016 HRM2_RS10430 4dd4188e4200289a29a153c44212ed49 293 SUPERFAMILY SSF53850 88 291 1.07E-29 T 22-04-2016 HRM2_RS21265 b3be903f2dbf6bd92f2f98b026f62c80 251 SUPERFAMILY SSF56214 117 223 7.33E-21 T 22-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 HRM2_RS21265 b3be903f2dbf6bd92f2f98b026f62c80 251 SUPERFAMILY SSF56214 11 109 9.29E-20 T 22-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 HRM2_RS21265 b3be903f2dbf6bd92f2f98b026f62c80 251 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 117 188 7.3E-14 T 22-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 HRM2_RS21265 b3be903f2dbf6bd92f2f98b026f62c80 251 PANTHER PTHR12215:SF10 5 191 1.3E-46 T 22-04-2016 HRM2_RS21265 b3be903f2dbf6bd92f2f98b026f62c80 251 PANTHER PTHR12215 5 191 1.3E-46 T 22-04-2016 HRM2_RS21265 b3be903f2dbf6bd92f2f98b026f62c80 251 Gene3D G3DSA:3.90.470.20 20 129 4.0E-29 T 22-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 HRM2_RS21265 b3be903f2dbf6bd92f2f98b026f62c80 251 Gene3D G3DSA:3.90.470.20 130 219 6.2E-22 T 22-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 HRM2_RS11155 11c185cc277c0b7eb82f26e8a3585d13 150 PANTHER PTHR21087:SF0 1 146 8.9E-37 T 22-04-2016 HRM2_RS11155 11c185cc277c0b7eb82f26e8a3585d13 150 ProSitePatterns PS01128 Shikimate kinase signature. 33 58 - T 22-04-2016 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS11155 11c185cc277c0b7eb82f26e8a3585d13 150 PANTHER PTHR21087 1 146 8.9E-37 T 22-04-2016 HRM2_RS11155 11c185cc277c0b7eb82f26e8a3585d13 150 PRINTS PR01100 Shikimate kinase family signature 4 17 8.4E-15 T 22-04-2016 HRM2_RS11155 11c185cc277c0b7eb82f26e8a3585d13 150 PRINTS PR01100 Shikimate kinase family signature 32 40 8.4E-15 T 22-04-2016 HRM2_RS11155 11c185cc277c0b7eb82f26e8a3585d13 150 PRINTS PR01100 Shikimate kinase family signature 71 88 8.4E-15 T 22-04-2016 HRM2_RS11155 11c185cc277c0b7eb82f26e8a3585d13 150 PRINTS PR01100 Shikimate kinase family signature 50 59 8.4E-15 T 22-04-2016 HRM2_RS11155 11c185cc277c0b7eb82f26e8a3585d13 150 Gene3D G3DSA:3.40.50.300 2 147 1.8E-33 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11155 11c185cc277c0b7eb82f26e8a3585d13 150 SUPERFAMILY SSF52540 3 146 5.44E-14 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11155 11c185cc277c0b7eb82f26e8a3585d13 150 Pfam PF01202 Shikimate kinase 2 146 6.4E-37 T 22-04-2016 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS06085 52180e61f8a064b8f14e3cd6c70a10bb 258 SMART SM00382 33 231 1.1E-16 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS06085 52180e61f8a064b8f14e3cd6c70a10bb 258 SUPERFAMILY SSF52540 9 253 2.85E-72 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06085 52180e61f8a064b8f14e3cd6c70a10bb 258 Pfam PF00005 ABC transporter 24 183 5.8E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS06085 52180e61f8a064b8f14e3cd6c70a10bb 258 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS06085 52180e61f8a064b8f14e3cd6c70a10bb 258 Gene3D G3DSA:3.40.50.300 8 255 1.5E-75 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06085 52180e61f8a064b8f14e3cd6c70a10bb 258 PIRSF PIRSF039085 5 258 1.1E-115 T 22-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 HRM2_RS06085 52180e61f8a064b8f14e3cd6c70a10bb 258 PANTHER PTHR24220:SF347 10 255 1.2E-138 T 22-04-2016 HRM2_RS06085 52180e61f8a064b8f14e3cd6c70a10bb 258 PANTHER PTHR24220 10 255 1.2E-138 T 22-04-2016 HRM2_RS19795 fb698da3d7b9e110cc6af97438237cd8 342 SUPERFAMILY SSF52402 181 341 6.61E-14 T 22-04-2016 HRM2_RS19795 fb698da3d7b9e110cc6af97438237cd8 342 Pfam PF00582 Universal stress protein family 6 174 5.2E-8 T 22-04-2016 IPR006016 UspA GO:0006950 HRM2_RS19795 fb698da3d7b9e110cc6af97438237cd8 342 Pfam PF00582 Universal stress protein family 182 341 1.4E-9 T 22-04-2016 IPR006016 UspA GO:0006950 HRM2_RS19795 fb698da3d7b9e110cc6af97438237cd8 342 SUPERFAMILY SSF52402 105 175 9.21E-15 T 22-04-2016 HRM2_RS19795 fb698da3d7b9e110cc6af97438237cd8 342 Gene3D G3DSA:3.40.50.620 4 175 8.0E-20 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS19795 fb698da3d7b9e110cc6af97438237cd8 342 SUPERFAMILY SSF52402 5 71 9.21E-15 T 22-04-2016 HRM2_RS19795 fb698da3d7b9e110cc6af97438237cd8 342 Gene3D G3DSA:3.40.50.620 177 342 3.0E-17 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS12240 abcc80251dce1d7df7c0559f30d089f6 621 SUPERFAMILY SSF51338 339 380 4.05E-19 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS12240 abcc80251dce1d7df7c0559f30d089f6 621 SUPERFAMILY SSF51338 23 85 4.05E-19 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS12240 abcc80251dce1d7df7c0559f30d089f6 621 Pfam PF01979 Amidohydrolase family 285 367 1.0E-9 T 22-04-2016 IPR006680 Amidohydrolase-related GO:0016787 HRM2_RS12240 abcc80251dce1d7df7c0559f30d089f6 621 Gene3D G3DSA:2.30.40.10 19 136 2.5E-19 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS12240 abcc80251dce1d7df7c0559f30d089f6 621 Hamap MF_01518 Adenine deaminase [ade]. 28 621 29.26 T 22-04-2016 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 HRM2_RS12240 abcc80251dce1d7df7c0559f30d089f6 621 Gene3D G3DSA:2.30.40.10 285 377 2.1E-15 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS12240 abcc80251dce1d7df7c0559f30d089f6 621 SUPERFAMILY SSF51556 85 332 9.83E-13 T 22-04-2016 IPR032466 Metal-dependent hydrolase HRM2_RS12240 abcc80251dce1d7df7c0559f30d089f6 621 Pfam PF13382 Adenine deaminase C-terminal domain 480 611 1.3E-38 T 22-04-2016 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 HRM2_RS12240 abcc80251dce1d7df7c0559f30d089f6 621 PANTHER PTHR11113:SF2 14 372 1.3E-129 T 22-04-2016 HRM2_RS12240 abcc80251dce1d7df7c0559f30d089f6 621 PANTHER PTHR11113:SF2 418 463 1.3E-129 T 22-04-2016 HRM2_RS12240 abcc80251dce1d7df7c0559f30d089f6 621 PANTHER PTHR11113:SF2 484 610 1.3E-129 T 22-04-2016 HRM2_RS12240 abcc80251dce1d7df7c0559f30d089f6 621 PANTHER PTHR11113 14 372 1.3E-129 T 22-04-2016 HRM2_RS12240 abcc80251dce1d7df7c0559f30d089f6 621 PANTHER PTHR11113 418 463 1.3E-129 T 22-04-2016 HRM2_RS12240 abcc80251dce1d7df7c0559f30d089f6 621 PANTHER PTHR11113 484 610 1.3E-129 T 22-04-2016 HRM2_RS06020 475273411f16e6168747e51e15b72b3e 286 PANTHER PTHR30477:SF0 1 278 2.4E-60 T 22-04-2016 HRM2_RS06020 475273411f16e6168747e51e15b72b3e 286 SUPERFAMILY SSF81345 15 270 1.15E-27 T 22-04-2016 IPR029022 ABC transporter, BtuC-like HRM2_RS06020 475273411f16e6168747e51e15b72b3e 286 Pfam PF00950 ABC 3 transport family 15 274 2.5E-63 T 22-04-2016 IPR001626 ABC-3 GO:0005524|GO:0006810|GO:0016020|GO:0042626 HRM2_RS06020 475273411f16e6168747e51e15b72b3e 286 PANTHER PTHR30477 1 278 2.4E-60 T 22-04-2016 HRM2_RS06020 475273411f16e6168747e51e15b72b3e 286 Gene3D G3DSA:1.10.3470.10 46 241 1.5E-5 T 22-04-2016 IPR029022 ABC transporter, BtuC-like HRM2_RS17650 a113b5fb5607578c2a648c238a3dc491 259 PANTHER PTHR21235:SF2 1 259 3.6E-118 T 22-04-2016 HRM2_RS17650 a113b5fb5607578c2a648c238a3dc491 259 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 256 3.4E-105 T 22-04-2016 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 UniPathway: UPA00031 HRM2_RS17650 a113b5fb5607578c2a648c238a3dc491 259 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 256 44.474 T 22-04-2016 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 UniPathway: UPA00031 HRM2_RS17650 a113b5fb5607578c2a648c238a3dc491 259 PANTHER PTHR21235 1 259 3.6E-118 T 22-04-2016 HRM2_RS17650 a113b5fb5607578c2a648c238a3dc491 259 Gene3D G3DSA:3.20.20.70 4 256 5.7E-95 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS17650 a113b5fb5607578c2a648c238a3dc491 259 SUPERFAMILY SSF51366 1 256 6.36E-77 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 HRM2_RS17650 a113b5fb5607578c2a648c238a3dc491 259 Pfam PF00977 Histidine biosynthesis protein 5 240 2.7E-79 T 22-04-2016 IPR006062 Histidine biosynthesis GO:0000105 HRM2_RS12475 b9a99923febab77879b06f40fc64654c 349 Gene3D G3DSA:1.10.8.60 178 229 1.5E-18 T 22-04-2016 HRM2_RS12475 b9a99923febab77879b06f40fc64654c 349 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 306 323 3.2E-5 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS12475 b9a99923febab77879b06f40fc64654c 349 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 323 343 3.2E-5 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS12475 b9a99923febab77879b06f40fc64654c 349 SUPERFAMILY SSF46689 269 343 2.08E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS12475 b9a99923febab77879b06f40fc64654c 349 Pfam PF00158 Sigma-54 interaction domain 5 172 4.8E-66 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS12475 b9a99923febab77879b06f40fc64654c 349 PANTHER PTHR32071 5 343 2.7E-129 T 22-04-2016 HRM2_RS12475 b9a99923febab77879b06f40fc64654c 349 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 219 228 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS12475 b9a99923febab77879b06f40fc64654c 349 Gene3D G3DSA:3.40.50.300 4 177 7.7E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12475 b9a99923febab77879b06f40fc64654c 349 SUPERFAMILY SSF52540 4 242 4.09E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12475 b9a99923febab77879b06f40fc64654c 349 SMART SM00382 25 172 1.5E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS12475 b9a99923febab77879b06f40fc64654c 349 Gene3D G3DSA:1.10.10.60 288 343 3.5E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS12475 b9a99923febab77879b06f40fc64654c 349 Gene3D G3DSA:1.10.10.60 230 250 3.5E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS12475 b9a99923febab77879b06f40fc64654c 349 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 29 42 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS12475 b9a99923febab77879b06f40fc64654c 349 Pfam PF02954 Bacterial regulatory protein, Fis family 300 338 3.0E-9 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS16675 815118493a5910eb0260d272aedeca01 241 Gene3D G3DSA:3.40.50.300 4 236 2.5E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16675 815118493a5910eb0260d272aedeca01 241 SUPERFAMILY SSF52540 4 238 2.66E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16675 815118493a5910eb0260d272aedeca01 241 Pfam PF00005 ABC transporter 23 167 7.9E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS16675 815118493a5910eb0260d272aedeca01 241 PANTHER PTHR24220:SF568 8 240 7.6E-112 T 22-04-2016 HRM2_RS16675 815118493a5910eb0260d272aedeca01 241 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS16675 815118493a5910eb0260d272aedeca01 241 SMART SM00382 31 216 4.8E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS16675 815118493a5910eb0260d272aedeca01 241 PANTHER PTHR24220 8 240 7.6E-112 T 22-04-2016 HRM2_RS03565 23700d627f6632ced4b01f427ec734a6 295 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 142 230 3.1E-19 T 22-04-2016 HRM2_RS03565 23700d627f6632ced4b01f427ec734a6 295 SUPERFAMILY SSF55166 77 168 5.41E-25 T 22-04-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain HRM2_RS03565 23700d627f6632ced4b01f427ec734a6 295 SUPERFAMILY SSF55166 201 231 5.41E-25 T 22-04-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain HRM2_RS22370 28ac3ec2dd1b86f2588d1d8aa707014d 497 Pfam PF00672 HAMP domain 210 275 3.3E-14 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS22370 28ac3ec2dd1b86f2588d1d8aa707014d 497 PANTHER PTHR24423 225 493 4.4E-58 T 22-04-2016 HRM2_RS22370 28ac3ec2dd1b86f2588d1d8aa707014d 497 SUPERFAMILY SSF158472 227 276 4.32E-11 T 22-04-2016 HRM2_RS22370 28ac3ec2dd1b86f2588d1d8aa707014d 497 SMART SM00388 280 344 9.4E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS22370 28ac3ec2dd1b86f2588d1d8aa707014d 497 SMART SM00387 385 497 3.0E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS22370 28ac3ec2dd1b86f2588d1d8aa707014d 497 Gene3D G3DSA:3.30.565.10 331 494 7.1E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS22370 28ac3ec2dd1b86f2588d1d8aa707014d 497 SMART SM00304 227 279 5.6E-14 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS22370 28ac3ec2dd1b86f2588d1d8aa707014d 497 Gene3D G3DSA:1.10.287.130 270 330 9.9E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS22370 28ac3ec2dd1b86f2588d1d8aa707014d 497 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 389 495 4.2E-19 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS22370 28ac3ec2dd1b86f2588d1d8aa707014d 497 Pfam PF00512 His Kinase A (phospho-acceptor) domain 281 342 1.9E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS22370 28ac3ec2dd1b86f2588d1d8aa707014d 497 SUPERFAMILY SSF47384 263 343 2.75E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS22370 28ac3ec2dd1b86f2588d1d8aa707014d 497 SUPERFAMILY SSF55874 333 494 2.89E-35 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS22370 28ac3ec2dd1b86f2588d1d8aa707014d 497 PRINTS PR00344 Bacterial sensor protein C-terminal signature 457 475 1.12E-11 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS22370 28ac3ec2dd1b86f2588d1d8aa707014d 497 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 436 1.12E-11 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS22370 28ac3ec2dd1b86f2588d1d8aa707014d 497 PRINTS PR00344 Bacterial sensor protein C-terminal signature 440 450 1.12E-11 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS04000 21c43503e45281d9247f9a3d9ecc5c29 292 SUPERFAMILY SSF103481 40 141 1.57E-11 T 22-04-2016 HRM2_RS04000 21c43503e45281d9247f9a3d9ecc5c29 292 TIGRFAM TIGR00688 rarD: protein RarD 7 258 1.0E-68 T 22-04-2016 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 HRM2_RS04000 21c43503e45281d9247f9a3d9ecc5c29 292 Pfam PF00892 EamA-like transporter family 7 141 1.1E-14 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS04000 21c43503e45281d9247f9a3d9ecc5c29 292 PANTHER PTHR22911 7 291 4.3E-114 T 22-04-2016 HRM2_RS04000 21c43503e45281d9247f9a3d9ecc5c29 292 SUPERFAMILY SSF103481 208 285 2.35E-9 T 22-04-2016 HRM2_RS04000 21c43503e45281d9247f9a3d9ecc5c29 292 PANTHER PTHR22911:SF41 7 291 4.3E-114 T 22-04-2016 HRM2_RS01180 8d0926c7da0cfb661a84918e61141cf0 339 PANTHER PTHR10799 206 333 4.1E-29 T 22-04-2016 HRM2_RS01180 8d0926c7da0cfb661a84918e61141cf0 339 PANTHER PTHR10799:SF750 206 333 4.1E-29 T 22-04-2016 HRM2_RS01180 8d0926c7da0cfb661a84918e61141cf0 339 SUPERFAMILY SSF55073 181 334 3.06E-45 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS01180 8d0926c7da0cfb661a84918e61141cf0 339 Pfam PF00990 Diguanylate cyclase, GGDEF domain 176 332 5.4E-45 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS01180 8d0926c7da0cfb661a84918e61141cf0 339 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 175 335 2.5E-47 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS01180 8d0926c7da0cfb661a84918e61141cf0 339 Gene3D G3DSA:3.30.70.270 178 335 7.4E-52 T 22-04-2016 HRM2_RS01180 8d0926c7da0cfb661a84918e61141cf0 339 SMART SM00267 162 336 1.9E-51 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS03040 35e921c5d0f871507dd8c5dcfae0f060 262 PANTHER PTHR11558 1 261 1.3E-117 T 22-04-2016 HRM2_RS03040 35e921c5d0f871507dd8c5dcfae0f060 262 SUPERFAMILY SSF53335 1 261 4.36E-78 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS03040 35e921c5d0f871507dd8c5dcfae0f060 262 Gene3D G3DSA:2.30.140.10 1 46 2.0E-17 T 22-04-2016 HRM2_RS03040 35e921c5d0f871507dd8c5dcfae0f060 262 TIGRFAM TIGR00417 speE: spermidine synthase 4 262 1.8E-97 T 22-04-2016 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|UniPathway: UPA00248 HRM2_RS03040 35e921c5d0f871507dd8c5dcfae0f060 262 Pfam PF01564 Spermine/spermidine synthase 2 226 2.1E-80 T 22-04-2016 HRM2_RS03040 35e921c5d0f871507dd8c5dcfae0f060 262 Gene3D G3DSA:3.40.50.150 47 261 4.4E-80 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS03040 35e921c5d0f871507dd8c5dcfae0f060 262 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 71 84 - T 22-04-2016 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|UniPathway: UPA00248 HRM2_RS03040 35e921c5d0f871507dd8c5dcfae0f060 262 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 1 260 32.484 T 22-04-2016 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|UniPathway: UPA00248 HRM2_RS24875 ec62219127710cbac4fe8d660262a4f9 280 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 2 42 7.9E-6 T 22-04-2016 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 HRM2_RS24875 ec62219127710cbac4fe8d660262a4f9 280 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 2 32 8.5E-7 T 22-04-2016 IPR013422 CRISPR-associated protein Cas5, N-terminal HRM2_RS22930 ee08b72308fbe81eb1172f4eec64be72 281 SUPERFAMILY SSF103481 37 134 7.45E-10 T 22-04-2016 HRM2_RS22930 ee08b72308fbe81eb1172f4eec64be72 281 SUPERFAMILY SSF103481 205 278 1.03E-8 T 22-04-2016 HRM2_RS22930 ee08b72308fbe81eb1172f4eec64be72 281 PANTHER PTHR22911 4 278 9.8E-53 T 22-04-2016 HRM2_RS22930 ee08b72308fbe81eb1172f4eec64be72 281 PANTHER PTHR22911:SF61 4 278 9.8E-53 T 22-04-2016 HRM2_RS05425 b284b4686ac0fa73c4cf2568b0f13134 352 Gene3D G3DSA:3.30.420.40 188 308 1.2E-10 T 22-04-2016 HRM2_RS05425 b284b4686ac0fa73c4cf2568b0f13134 352 TIGRFAM TIGR01175 pilM: type IV pilus assembly protein PilM 6 348 4.0E-70 T 22-04-2016 IPR005883 Type IV pilus assembly protein PilM HRM2_RS05425 b284b4686ac0fa73c4cf2568b0f13134 352 PANTHER PTHR32432:SF3 1 347 2.7E-57 T 22-04-2016 HRM2_RS05425 b284b4686ac0fa73c4cf2568b0f13134 352 PANTHER PTHR32432 1 347 2.7E-57 T 22-04-2016 HRM2_RS05425 b284b4686ac0fa73c4cf2568b0f13134 352 Gene3D G3DSA:3.30.420.40 4 89 1.4E-7 T 22-04-2016 HRM2_RS05425 b284b4686ac0fa73c4cf2568b0f13134 352 Pfam PF11104 Type IV pilus assembly protein PilM; 11 348 2.5E-66 T 22-04-2016 IPR005883 Type IV pilus assembly protein PilM HRM2_RS05425 b284b4686ac0fa73c4cf2568b0f13134 352 SUPERFAMILY SSF53067 60 171 6.47E-16 T 22-04-2016 HRM2_RS05425 b284b4686ac0fa73c4cf2568b0f13134 352 SUPERFAMILY SSF53067 163 311 6.79E-14 T 22-04-2016 HRM2_RS05425 b284b4686ac0fa73c4cf2568b0f13134 352 SUPERFAMILY SSF53067 9 91 6.79E-14 T 22-04-2016 HRM2_RS05425 b284b4686ac0fa73c4cf2568b0f13134 352 SMART SM00842 9 175 0.0029 T 22-04-2016 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 HRM2_RS05425 b284b4686ac0fa73c4cf2568b0f13134 352 PIRSF PIRSF019169 1 350 4.7E-91 T 22-04-2016 IPR005883 Type IV pilus assembly protein PilM HRM2_RS04855 158620e0786f4c0092ecebaf8280ab64 240 PANTHER PTHR30183 6 232 9.8E-80 T 22-04-2016 HRM2_RS04855 158620e0786f4c0092ecebaf8280ab64 240 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 227 1.2E-19 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS04855 158620e0786f4c0092ecebaf8280ab64 240 SUPERFAMILY SSF161098 11 218 5.63E-48 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS04855 158620e0786f4c0092ecebaf8280ab64 240 Gene3D G3DSA:1.10.3720.10 11 231 1.0E-42 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS04855 158620e0786f4c0092ecebaf8280ab64 240 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 16 223 4.5E-63 T 22-04-2016 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 HRM2_RS05895 9415df98f07ada2124e538210a744ae1 416 SUPERFAMILY SSF55073 220 413 6.12E-54 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS05895 9415df98f07ada2124e538210a744ae1 416 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 227 406 1.3E-35 T 22-04-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 HRM2_RS05895 9415df98f07ada2124e538210a744ae1 416 PANTHER PTHR11920 194 412 1.0E-56 T 22-04-2016 HRM2_RS05895 9415df98f07ada2124e538210a744ae1 416 Gene3D G3DSA:3.30.70.1230 224 411 5.6E-45 T 22-04-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 HRM2_RS05895 9415df98f07ada2124e538210a744ae1 416 PANTHER PTHR11920:SF341 194 412 1.0E-56 T 22-04-2016 HRM2_RS05895 9415df98f07ada2124e538210a744ae1 416 SMART SM00044 193 389 1.1E-20 T 22-04-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 HRM2_RS15155 6b35bffff9e8f9eaa13771df71318b26 177 SUPERFAMILY SSF47240 1 159 7.22E-55 T 22-04-2016 IPR009078 Ferritin-like superfamily HRM2_RS15155 6b35bffff9e8f9eaa13771df71318b26 177 Gene3D G3DSA:1.20.1260.10 1 164 3.0E-57 T 22-04-2016 IPR012347 Ferritin-related HRM2_RS15155 6b35bffff9e8f9eaa13771df71318b26 177 PANTHER PTHR11431:SF4 8 164 7.9E-43 T 22-04-2016 HRM2_RS15155 6b35bffff9e8f9eaa13771df71318b26 177 Pfam PF00210 Ferritin-like domain 8 143 2.4E-41 T 22-04-2016 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 HRM2_RS15155 6b35bffff9e8f9eaa13771df71318b26 177 PANTHER PTHR11431 8 164 7.9E-43 T 22-04-2016 IPR001519 Ferritin GO:0006826|GO:0006879|GO:0008199 HRM2_RS11380 4db6cc71d904df0a902cca1996302525 519 Gene3D G3DSA:3.30.70.20 357 394 1.7E-9 T 22-04-2016 HRM2_RS11380 4db6cc71d904df0a902cca1996302525 519 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 349 360 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS11380 4db6cc71d904df0a902cca1996302525 519 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 265 276 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS11380 4db6cc71d904df0a902cca1996302525 519 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 466 477 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS11380 4db6cc71d904df0a902cca1996302525 519 Pfam PF12801 4Fe-4S binding domain 57 99 5.1E-11 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS11380 4db6cc71d904df0a902cca1996302525 519 Pfam PF12801 4Fe-4S binding domain 190 230 1.3E-6 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS11380 4db6cc71d904df0a902cca1996302525 519 Gene3D G3DSA:3.30.70.20 395 434 4.1E-7 T 22-04-2016 HRM2_RS11380 4db6cc71d904df0a902cca1996302525 519 SUPERFAMILY SSF54862 66 87 2.54E-18 T 22-04-2016 HRM2_RS11380 4db6cc71d904df0a902cca1996302525 519 SUPERFAMILY SSF54862 191 301 2.54E-18 T 22-04-2016 HRM2_RS11380 4db6cc71d904df0a902cca1996302525 519 Gene3D G3DSA:1.10.1060.10 275 305 1.4E-8 T 22-04-2016 HRM2_RS11380 4db6cc71d904df0a902cca1996302525 519 Gene3D G3DSA:1.10.1060.10 341 356 1.4E-8 T 22-04-2016 HRM2_RS11380 4db6cc71d904df0a902cca1996302525 519 Pfam PF13183 4Fe-4S dicluster domain 263 362 1.1E-6 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS11380 4db6cc71d904df0a902cca1996302525 519 SUPERFAMILY SSF54862 340 485 7.67E-19 T 22-04-2016 HRM2_RS11380 4db6cc71d904df0a902cca1996302525 519 PANTHER PTHR30176:SF2 59 411 2.3E-48 T 22-04-2016 HRM2_RS11380 4db6cc71d904df0a902cca1996302525 519 PANTHER PTHR30176 59 411 2.3E-48 T 22-04-2016 HRM2_RS11380 4db6cc71d904df0a902cca1996302525 519 Pfam PF12838 4Fe-4S dicluster domain 435 478 9.7E-10 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS11380 4db6cc71d904df0a902cca1996302525 519 Gene3D G3DSA:3.30.70.20 435 486 4.3E-12 T 22-04-2016 HRM2_RS11380 4db6cc71d904df0a902cca1996302525 519 Gene3D G3DSA:3.30.70.20 205 274 3.1E-13 T 22-04-2016 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 Pfam PF00515 Tetratricopeptide repeat 611 644 6.7E-7 T 22-04-2016 IPR001440 Tetratricopeptide repeat 1 GO:0005515 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 Gene3D G3DSA:1.25.40.10 542 752 7.5E-40 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 SUPERFAMILY SSF48452 545 747 1.01E-29 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 SUPERFAMILY SSF48452 209 414 1.2E-33 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 Gene3D G3DSA:1.25.40.10 22 304 2.6E-46 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 Gene3D G3DSA:1.25.40.10 311 531 9.3E-39 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 Pfam PF13181 Tetratricopeptide repeat 548 575 2.8E-4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 Pfam PF13181 Tetratricopeptide repeat 718 746 0.03 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 SUPERFAMILY SSF48452 367 516 6.64E-27 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 SMART SM00028 680 713 110.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 SMART SM00028 63 96 310.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 SMART SM00028 577 610 4.5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 SMART SM00028 472 505 0.0084 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 SMART SM00028 404 437 180.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 SMART SM00028 714 747 0.031 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 SMART SM00028 438 471 0.048 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 SMART SM00028 268 301 0.037 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 SMART SM00028 166 199 3.2 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 SMART SM00028 29 62 0.051 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 SMART SM00028 234 267 0.0027 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 SMART SM00028 611 644 9.7E-6 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 SMART SM00028 370 403 0.71 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 SMART SM00028 336 369 32.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 SMART SM00028 543 576 0.0025 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 Pfam PF13414 TPR repeat 36 77 2.5E-9 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 PANTHER PTHR23083 435 481 7.8E-83 T 22-04-2016 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 PANTHER PTHR23083 553 748 7.8E-83 T 22-04-2016 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 PANTHER PTHR23083 68 111 7.8E-83 T 22-04-2016 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 PANTHER PTHR23083 162 400 7.8E-83 T 22-04-2016 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 Pfam PF13432 Tetratricopeptide repeat 442 504 2.3E-4 T 22-04-2016 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 Pfam PF13432 Tetratricopeptide repeat 376 416 0.0016 T 22-04-2016 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 SUPERFAMILY SSF48452 29 200 1.01E-24 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 Pfam PF14559 Tetratricopeptide repeat 282 336 6.5E-6 T 22-04-2016 HRM2_RS10270 a4d86c4f0b2adb3e0f0eb4b9d8e9b224 760 Pfam PF14559 Tetratricopeptide repeat 177 240 3.1E-7 T 22-04-2016 HRM2_RS23915 5630eb3b33d28fb53fa5fe9d83eb227f 108 PANTHER PTHR37309:SF1 1 107 2.3E-17 T 22-04-2016 HRM2_RS23915 5630eb3b33d28fb53fa5fe9d83eb227f 108 PANTHER PTHR37309 1 107 2.3E-17 T 22-04-2016 HRM2_RS23915 5630eb3b33d28fb53fa5fe9d83eb227f 108 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 2 101 2.4E-23 T 22-04-2016 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV HRM2_RS08620 83116271c93dd4618590fe8f9933a556 384 PANTHER PTHR30349 94 381 3.9E-43 T 22-04-2016 HRM2_RS08620 83116271c93dd4618590fe8f9933a556 384 Pfam PF00589 Phage integrase family 192 352 1.2E-33 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS08620 83116271c93dd4618590fe8f9933a556 384 Gene3D G3DSA:1.10.150.130 80 185 4.9E-8 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal HRM2_RS08620 83116271c93dd4618590fe8f9933a556 384 Gene3D G3DSA:1.10.443.10 190 365 1.5E-43 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS08620 83116271c93dd4618590fe8f9933a556 384 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 81 131 1.2E-7 T 22-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 HRM2_RS08620 83116271c93dd4618590fe8f9933a556 384 PANTHER PTHR30349:SF20 94 381 3.9E-43 T 22-04-2016 HRM2_RS08620 83116271c93dd4618590fe8f9933a556 384 SUPERFAMILY SSF56349 80 359 4.71E-63 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HRM2_RS04540 56bd58ec2c0d694e1483fc3c0d4ae707 395 PANTHER PTHR30563 50 379 2.8E-52 T 22-04-2016 HRM2_RS04540 56bd58ec2c0d694e1483fc3c0d4ae707 395 Pfam PF02646 RmuC family 88 373 8.1E-89 T 22-04-2016 IPR003798 DNA recombination RmuC HRM2_RS20265 4047e072b9bdaee131e606113b3f7045 88 Pfam PF00462 Glutaredoxin 7 70 5.2E-13 T 22-04-2016 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 HRM2_RS20265 4047e072b9bdaee131e606113b3f7045 88 Gene3D G3DSA:3.40.30.10 7 84 1.5E-18 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS20265 4047e072b9bdaee131e606113b3f7045 88 SUPERFAMILY SSF52833 7 83 4.19E-16 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS15010 c7a24af17fa2a0a063a9a7333483147b 258 PANTHER PTHR30487 1 256 6.0E-83 T 22-04-2016 HRM2_RS15010 c7a24af17fa2a0a063a9a7333483147b 258 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 115 132 8.6E-14 T 22-04-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- HRM2_RS15010 c7a24af17fa2a0a063a9a7333483147b 258 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 172 182 8.6E-14 T 22-04-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- HRM2_RS15010 c7a24af17fa2a0a063a9a7333483147b 258 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 183 194 8.6E-14 T 22-04-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- HRM2_RS15010 c7a24af17fa2a0a063a9a7333483147b 258 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 195 210 8.6E-14 T 22-04-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- HRM2_RS15010 c7a24af17fa2a0a063a9a7333483147b 258 Pfam PF01478 Type IV leader peptidase family 108 212 5.8E-17 T 22-04-2016 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 HRM2_RS15010 c7a24af17fa2a0a063a9a7333483147b 258 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 14 96 1.3E-30 T 22-04-2016 IPR010627 Peptidase A24A, N-terminal KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- HRM2_RS15010 c7a24af17fa2a0a063a9a7333483147b 258 PANTHER PTHR30487:SF0 1 256 6.0E-83 T 22-04-2016 HRM2_RS16760 4c0ca9c952866f22ad2796e11520715f 558 PANTHER PTHR34614 1 558 3.1E-74 T 22-04-2016 HRM2_RS16760 4c0ca9c952866f22ad2796e11520715f 558 Pfam PF14104 Domain of unknown function (DUF4277) 11 111 8.4E-22 T 22-04-2016 IPR025457 Domain of unknown function DUF4277 HRM2_RS08585 4c0ca9c952866f22ad2796e11520715f 558 PANTHER PTHR34614 1 558 3.1E-74 T 22-04-2016 HRM2_RS08585 4c0ca9c952866f22ad2796e11520715f 558 Pfam PF14104 Domain of unknown function (DUF4277) 11 111 8.4E-22 T 22-04-2016 IPR025457 Domain of unknown function DUF4277 HRM2_RS12900 39c4fc9f312ecfe070ae347671861dc9 833 SUPERFAMILY SSF53187 289 534 4.96E-19 T 22-04-2016 HRM2_RS12900 39c4fc9f312ecfe070ae347671861dc9 833 Pfam PF03412 Peptidase C39 family 121 237 2.8E-12 T 22-04-2016 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 HRM2_RS12900 39c4fc9f312ecfe070ae347671861dc9 833 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 319 489 7.8E-9 T 22-04-2016 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 HRM2_RS12900 39c4fc9f312ecfe070ae347671861dc9 833 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 607 706 7.9E-13 T 22-04-2016 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 HRM2_RS12900 39c4fc9f312ecfe070ae347671861dc9 833 Gene3D G3DSA:3.40.630.10 277 554 1.1E-25 T 22-04-2016 HRM2_RS12900 39c4fc9f312ecfe070ae347671861dc9 833 Gene3D G3DSA:3.40.630.10 557 832 3.4E-42 T 22-04-2016 HRM2_RS12900 39c4fc9f312ecfe070ae347671861dc9 833 SUPERFAMILY SSF53187 599 828 1.52E-27 T 22-04-2016 HRM2_RS24420 f3711c18e45581b8c535539401bf85f7 193 Pfam PF13242 HAD-hyrolase-like 103 178 3.0E-16 T 22-04-2016 HRM2_RS24420 f3711c18e45581b8c535539401bf85f7 193 PANTHER PTHR23133:SF3 4 184 3.6E-39 T 22-04-2016 HRM2_RS24420 f3711c18e45581b8c535539401bf85f7 193 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 7 145 7.6E-30 T 22-04-2016 IPR006549 HAD-superfamily hydrolase,subfamily IIIA HRM2_RS24420 f3711c18e45581b8c535539401bf85f7 193 PANTHER PTHR23133 4 184 3.6E-39 T 22-04-2016 HRM2_RS24420 f3711c18e45581b8c535539401bf85f7 193 Gene3D G3DSA:3.40.50.1000 4 182 1.5E-52 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS24420 f3711c18e45581b8c535539401bf85f7 193 PIRSF PIRSF004682 1 187 7.4E-57 T 22-04-2016 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 HRM2_RS24420 f3711c18e45581b8c535539401bf85f7 193 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 7 150 7.7E-42 T 22-04-2016 IPR006543 Histidinol-phosphate phosphatase GO:0016791 HRM2_RS24420 f3711c18e45581b8c535539401bf85f7 193 SUPERFAMILY SSF56784 7 184 2.0E-41 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS00835 54651e37192731a00a66a5ec24d70ac6 639 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 447 474 1.5E-15 T 22-04-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HRM2_RS00835 54651e37192731a00a66a5ec24d70ac6 639 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 366 395 1.5E-15 T 22-04-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HRM2_RS00835 54651e37192731a00a66a5ec24d70ac6 639 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 476 505 1.5E-15 T 22-04-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HRM2_RS00835 54651e37192731a00a66a5ec24d70ac6 639 PANTHER PTHR32089 327 606 8.8E-50 T 22-04-2016 HRM2_RS00835 54651e37192731a00a66a5ec24d70ac6 639 PANTHER PTHR32089 254 306 8.8E-50 T 22-04-2016 HRM2_RS00835 54651e37192731a00a66a5ec24d70ac6 639 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 415 590 2.1E-28 T 22-04-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HRM2_RS00835 54651e37192731a00a66a5ec24d70ac6 639 SMART SM00283 349 607 7.1E-20 T 22-04-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HRM2_RS00835 54651e37192731a00a66a5ec24d70ac6 639 Gene3D G3DSA:1.10.287.950 365 574 4.9E-42 T 22-04-2016 HRM2_RS00835 54651e37192731a00a66a5ec24d70ac6 639 PANTHER PTHR32089:SF56 327 606 8.8E-50 T 22-04-2016 HRM2_RS00835 54651e37192731a00a66a5ec24d70ac6 639 PANTHER PTHR32089:SF56 254 306 8.8E-50 T 22-04-2016 HRM2_RS00835 54651e37192731a00a66a5ec24d70ac6 639 SUPERFAMILY SSF58104 331 593 4.84E-51 T 22-04-2016 HRM2_RS13165 0aeda7d9042c9ea7712fca56a35b206b 659 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 63 144 2.2E-22 T 22-04-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 HRM2_RS13165 0aeda7d9042c9ea7712fca56a35b206b 659 Gene3D G3DSA:3.40.50.720 262 349 1.4E-29 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS13165 0aeda7d9042c9ea7712fca56a35b206b 659 Gene3D G3DSA:3.40.50.720 513 601 1.4E-29 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS13165 0aeda7d9042c9ea7712fca56a35b206b 659 PANTHER PTHR11938 156 656 4.2E-98 T 22-04-2016 HRM2_RS13165 0aeda7d9042c9ea7712fca56a35b206b 659 PRINTS PR00419 Adrenodoxin reductase family signature 433 446 7.7E-20 T 22-04-2016 HRM2_RS13165 0aeda7d9042c9ea7712fca56a35b206b 659 PRINTS PR00419 Adrenodoxin reductase family signature 325 335 7.7E-20 T 22-04-2016 HRM2_RS13165 0aeda7d9042c9ea7712fca56a35b206b 659 PRINTS PR00419 Adrenodoxin reductase family signature 283 296 7.7E-20 T 22-04-2016 HRM2_RS13165 0aeda7d9042c9ea7712fca56a35b206b 659 PRINTS PR00419 Adrenodoxin reductase family signature 260 282 7.7E-20 T 22-04-2016 HRM2_RS13165 0aeda7d9042c9ea7712fca56a35b206b 659 PRINTS PR00419 Adrenodoxin reductase family signature 399 413 7.7E-20 T 22-04-2016 HRM2_RS13165 0aeda7d9042c9ea7712fca56a35b206b 659 SUPERFAMILY SSF51971 258 509 4.06E-54 T 22-04-2016 HRM2_RS13165 0aeda7d9042c9ea7712fca56a35b206b 659 Gene3D G3DSA:1.10.1060.10 155 261 5.2E-23 T 22-04-2016 HRM2_RS13165 0aeda7d9042c9ea7712fca56a35b206b 659 Gene3D G3DSA:1.10.1060.10 607 650 1.4E-6 T 22-04-2016 HRM2_RS13165 0aeda7d9042c9ea7712fca56a35b206b 659 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 155 238 5.8E-20 T 22-04-2016 IPR028261 Dihydroprymidine dehydrogenase domain II HRM2_RS13165 0aeda7d9042c9ea7712fca56a35b206b 659 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 74 85 - T 22-04-2016 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 HRM2_RS13165 0aeda7d9042c9ea7712fca56a35b206b 659 SUPERFAMILY SSF46548 144 269 1.83E-16 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS13165 0aeda7d9042c9ea7712fca56a35b206b 659 SMART SM00928 61 106 8.3E-14 T 22-04-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 HRM2_RS13165 0aeda7d9042c9ea7712fca56a35b206b 659 SUPERFAMILY SSF140490 58 149 1.06E-24 T 22-04-2016 HRM2_RS13165 0aeda7d9042c9ea7712fca56a35b206b 659 PANTHER PTHR11938:SF99 156 656 4.2E-98 T 22-04-2016 HRM2_RS13165 0aeda7d9042c9ea7712fca56a35b206b 659 SUPERFAMILY SSF46548 608 650 3.98E-5 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS13165 0aeda7d9042c9ea7712fca56a35b206b 659 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 260 564 3.3E-29 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS13165 0aeda7d9042c9ea7712fca56a35b206b 659 Gene3D G3DSA:3.50.50.60 350 509 3.2E-41 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS08910 dce88897d8af535d5bc0b55bc904d1d9 168 Pfam PF03061 Thioesterase superfamily 26 98 1.2E-19 T 22-04-2016 IPR006683 Thioesterase domain HRM2_RS08910 dce88897d8af535d5bc0b55bc904d1d9 168 SUPERFAMILY SSF54637 1 153 6.2E-45 T 22-04-2016 IPR029069 HotDog domain HRM2_RS08910 dce88897d8af535d5bc0b55bc904d1d9 168 PANTHER PTHR11049 3 154 2.5E-64 T 22-04-2016 HRM2_RS08910 dce88897d8af535d5bc0b55bc904d1d9 168 Gene3D G3DSA:3.10.129.10 3 156 3.1E-55 T 22-04-2016 IPR029069 HotDog domain HRM2_RS18075 be56d243bbdc1102cda6118cebf23a3b 449 SUPERFAMILY SSF48019 260 444 9.64E-73 T 22-04-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 HRM2_RS18075 be56d243bbdc1102cda6118cebf23a3b 449 SUPERFAMILY SSF52540 13 231 2.86E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18075 be56d243bbdc1102cda6118cebf23a3b 449 PANTHER PTHR13779:SF7 8 439 3.5E-196 T 22-04-2016 HRM2_RS18075 be56d243bbdc1102cda6118cebf23a3b 449 SMART SM00382 51 168 2.2E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS18075 be56d243bbdc1102cda6118cebf23a3b 449 Pfam PF12002 MgsA AAA+ ATPase C terminal 275 440 2.2E-65 T 22-04-2016 IPR021886 MgsA AAA+ ATPase C-terminal HRM2_RS18075 be56d243bbdc1102cda6118cebf23a3b 449 Gene3D G3DSA:1.10.3710.10 355 447 5.7E-32 T 22-04-2016 HRM2_RS18075 be56d243bbdc1102cda6118cebf23a3b 449 Gene3D G3DSA:3.40.50.300 16 156 7.5E-29 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18075 be56d243bbdc1102cda6118cebf23a3b 449 Pfam PF16193 AAA C-terminal domain 193 274 5.2E-22 T 22-04-2016 IPR032423 AAA ATPase, C-terminal domain HRM2_RS18075 be56d243bbdc1102cda6118cebf23a3b 449 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 56 163 1.6E-15 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HRM2_RS18075 be56d243bbdc1102cda6118cebf23a3b 449 PANTHER PTHR13779 8 439 3.5E-196 T 22-04-2016 HRM2_RS18075 be56d243bbdc1102cda6118cebf23a3b 449 Gene3D G3DSA:1.10.8.60 157 224 4.5E-11 T 22-04-2016 HRM2_RS18075 be56d243bbdc1102cda6118cebf23a3b 449 Gene3D G3DSA:1.20.272.10 256 354 3.0E-40 T 22-04-2016 HRM2_RS08125 b7c4e368b3044ca905f5d0550ed154ef 459 Pfam PF13487 HD domain 275 336 2.2E-17 T 22-04-2016 HRM2_RS08125 b7c4e368b3044ca905f5d0550ed154ef 459 Gene3D G3DSA:1.10.3210.10 220 344 7.8E-8 T 22-04-2016 IPR006674 HD domain HRM2_RS08125 b7c4e368b3044ca905f5d0550ed154ef 459 SUPERFAMILY SSF109604 216 385 3.49E-14 T 22-04-2016 HRM2_RS00505 a2f0d2a908103a605b097671b64e27dd 344 Gene3D G3DSA:1.10.3470.10 13 341 6.3E-93 T 22-04-2016 IPR029022 ABC transporter, BtuC-like HRM2_RS00505 a2f0d2a908103a605b097671b64e27dd 344 SUPERFAMILY SSF81345 6 337 1.57E-75 T 22-04-2016 IPR029022 ABC transporter, BtuC-like HRM2_RS00505 a2f0d2a908103a605b097671b64e27dd 344 PANTHER PTHR30472:SF25 5 344 1.7E-122 T 22-04-2016 HRM2_RS00505 a2f0d2a908103a605b097671b64e27dd 344 PANTHER PTHR30472 5 344 1.7E-122 T 22-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 HRM2_RS00505 a2f0d2a908103a605b097671b64e27dd 344 Pfam PF01032 FecCD transport family 26 338 1.1E-82 T 22-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 HRM2_RS23955 96042a3922f592b410b5ab0da4a19ac8 392 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 2.7E-125 T 22-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 HRM2_RS23955 96042a3922f592b410b5ab0da4a19ac8 392 Gene3D G3DSA:3.40.47.10 3 126 3.0E-50 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS23955 96042a3922f592b410b5ab0da4a19ac8 392 Gene3D G3DSA:3.40.47.10 200 272 3.0E-50 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS23955 96042a3922f592b410b5ab0da4a19ac8 392 PANTHER PTHR18919:SF98 1 391 9.9E-160 T 22-04-2016 HRM2_RS23955 96042a3922f592b410b5ab0da4a19ac8 392 Gene3D G3DSA:3.40.47.10 274 391 3.8E-64 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS23955 96042a3922f592b410b5ab0da4a19ac8 392 Gene3D G3DSA:3.40.47.10 140 184 3.8E-64 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS23955 96042a3922f592b410b5ab0da4a19ac8 392 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 22-04-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 HRM2_RS23955 96042a3922f592b410b5ab0da4a19ac8 392 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 22-04-2016 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 Reactome: REACT_22258 HRM2_RS23955 96042a3922f592b410b5ab0da4a19ac8 392 Pfam PF00108 Thiolase, N-terminal domain 5 259 1.2E-59 T 22-04-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 HRM2_RS23955 96042a3922f592b410b5ab0da4a19ac8 392 PANTHER PTHR18919 1 391 9.9E-160 T 22-04-2016 HRM2_RS23955 96042a3922f592b410b5ab0da4a19ac8 392 SUPERFAMILY SSF53901 268 391 1.11E-41 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS23955 96042a3922f592b410b5ab0da4a19ac8 392 ProSitePatterns PS00099 Thiolases active site. 373 386 - T 22-04-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 HRM2_RS23955 96042a3922f592b410b5ab0da4a19ac8 392 Pfam PF02803 Thiolase, C-terminal domain 267 391 7.8E-46 T 22-04-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 HRM2_RS23955 96042a3922f592b410b5ab0da4a19ac8 392 PIRSF PIRSF000429 1 392 1.2E-117 T 22-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 HRM2_RS23955 96042a3922f592b410b5ab0da4a19ac8 392 SUPERFAMILY SSF53901 3 267 2.08E-58 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS09460 5d8afdbaa1669f42b3068edabb34070d 267 Gene3D G3DSA:3.20.20.190 2 266 1.2E-63 T 22-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 HRM2_RS09460 5d8afdbaa1669f42b3068edabb34070d 267 SUPERFAMILY SSF51695 2 266 1.02E-62 T 22-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 HRM2_RS09460 5d8afdbaa1669f42b3068edabb34070d 267 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 7 260 6.4E-36 T 22-04-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 HRM2_RS09460 5d8afdbaa1669f42b3068edabb34070d 267 PANTHER PTHR23344 1 267 2.0E-62 T 22-04-2016 IPR004129 Glycerophosphoryl diester phosphodiesterase GO:0008889 HRM2_RS10880 7d6bb0b9c72344d36478a0e8d65cd0e3 269 PANTHER PTHR30188:SF4 15 269 1.2E-92 T 22-04-2016 HRM2_RS10880 7d6bb0b9c72344d36478a0e8d65cd0e3 269 Pfam PF02405 Permease MlaE 50 266 7.3E-77 T 22-04-2016 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 HRM2_RS10880 7d6bb0b9c72344d36478a0e8d65cd0e3 269 PANTHER PTHR30188 15 269 1.2E-92 T 22-04-2016 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 HRM2_RS10880 7d6bb0b9c72344d36478a0e8d65cd0e3 269 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 23 268 2.7E-73 T 22-04-2016 IPR003453 ABC transport permease subunit MlaE, Proteobacteria HRM2_RS12305 f7859814d87e26a4ecc9fa3a55abc5e8 368 Pfam PF00155 Aminotransferase class I and II 33 357 3.7E-57 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HRM2_RS12305 f7859814d87e26a4ecc9fa3a55abc5e8 368 Gene3D G3DSA:3.40.640.10 45 263 1.3E-68 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS12305 f7859814d87e26a4ecc9fa3a55abc5e8 368 Gene3D G3DSA:3.90.1150.10 264 361 2.1E-22 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS12305 f7859814d87e26a4ecc9fa3a55abc5e8 368 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 4 361 58.225 T 22-04-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9|UniPathway: UPA00031 HRM2_RS12305 f7859814d87e26a4ecc9fa3a55abc5e8 368 PANTHER PTHR11751 8 360 2.4E-94 T 22-04-2016 HRM2_RS12305 f7859814d87e26a4ecc9fa3a55abc5e8 368 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 7 360 3.7E-106 T 22-04-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9|UniPathway: UPA00031 HRM2_RS12305 f7859814d87e26a4ecc9fa3a55abc5e8 368 SUPERFAMILY SSF53383 14 361 1.35E-86 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS12305 f7859814d87e26a4ecc9fa3a55abc5e8 368 PANTHER PTHR11751:SF347 8 360 2.4E-94 T 22-04-2016 HRM2_RS05840 a3c29cf654ea0305890a760b59f0946b 463 Gene3D G3DSA:3.40.50.300 141 316 2.2E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05840 a3c29cf654ea0305890a760b59f0946b 463 Gene3D G3DSA:1.10.10.60 409 459 2.9E-6 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS05840 a3c29cf654ea0305890a760b59f0946b 463 Pfam PF00072 Response regulator receiver domain 6 113 1.0E-27 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS05840 a3c29cf654ea0305890a760b59f0946b 463 SUPERFAMILY SSF52540 143 386 1.42E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05840 a3c29cf654ea0305890a760b59f0946b 463 SUPERFAMILY SSF46689 357 461 3.76E-8 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS05840 a3c29cf654ea0305890a760b59f0946b 463 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 357 366 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS05840 a3c29cf654ea0305890a760b59f0946b 463 SUPERFAMILY SSF52172 5 187 5.41E-42 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS05840 a3c29cf654ea0305890a760b59f0946b 463 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 168 181 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS05840 a3c29cf654ea0305890a760b59f0946b 463 SMART SM00448 4 115 3.8E-35 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS05840 a3c29cf654ea0305890a760b59f0946b 463 Gene3D G3DSA:3.40.50.2300 5 133 9.8E-37 T 22-04-2016 HRM2_RS05840 a3c29cf654ea0305890a760b59f0946b 463 Gene3D G3DSA:1.10.8.60 317 390 1.0E-24 T 22-04-2016 HRM2_RS05840 a3c29cf654ea0305890a760b59f0946b 463 Pfam PF00158 Sigma-54 interaction domain 144 311 2.1E-62 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS05840 a3c29cf654ea0305890a760b59f0946b 463 SMART SM00382 164 318 4.9E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS05840 a3c29cf654ea0305890a760b59f0946b 463 Pfam PF02954 Bacterial regulatory protein, Fis family 420 457 8.8E-5 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS05840 a3c29cf654ea0305890a760b59f0946b 463 PANTHER PTHR32071 1 458 3.8E-173 T 22-04-2016 HRM2_RS25580 845199d1152bd9741d0d22c67faeacc9 181 Pfam PF01323 DSBA-like thioredoxin domain 4 167 9.7E-17 T 22-04-2016 IPR001853 DSBA-like thioredoxin domain GO:0015035 HRM2_RS25580 845199d1152bd9741d0d22c67faeacc9 181 Gene3D G3DSA:3.40.30.10 3 170 4.5E-22 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS25580 845199d1152bd9741d0d22c67faeacc9 181 SUPERFAMILY SSF52833 3 170 1.45E-22 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS12410 5f41480932daeb07f569ebfc0bf34644 253 SUPERFAMILY SSF55681 35 223 9.11E-52 T 22-04-2016 HRM2_RS12410 5f41480932daeb07f569ebfc0bf34644 253 Hamap MF_00013 Octanoyltransferase [lipB]. 33 252 30.871 T 22-04-2016 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 HRM2_RS12410 5f41480932daeb07f569ebfc0bf34644 253 Gene3D G3DSA:3.90.1550.10 35 233 1.2E-61 T 22-04-2016 HRM2_RS12410 5f41480932daeb07f569ebfc0bf34644 253 Pfam PF03099 Biotin/lipoate A/B protein ligase family 92 199 1.6E-6 T 22-04-2016 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 HRM2_RS12410 5f41480932daeb07f569ebfc0bf34644 253 PANTHER PTHR10993 34 222 2.5E-60 T 22-04-2016 HRM2_RS12410 5f41480932daeb07f569ebfc0bf34644 253 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 111 158 5.0E-10 T 22-04-2016 HRM2_RS12410 5f41480932daeb07f569ebfc0bf34644 253 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 60 221 1.2E-43 T 22-04-2016 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 HRM2_RS12410 5f41480932daeb07f569ebfc0bf34644 253 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 107 122 - T 22-04-2016 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 HRM2_RS02430 628a59d26ac536b657c058bc6d80b0f9 238 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS02430 628a59d26ac536b657c058bc6d80b0f9 238 SMART SM00382 30 215 6.1E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS02430 628a59d26ac536b657c058bc6d80b0f9 238 Gene3D G3DSA:3.40.50.300 2 232 1.7E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02430 628a59d26ac536b657c058bc6d80b0f9 238 SUPERFAMILY SSF52540 3 228 8.42E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02430 628a59d26ac536b657c058bc6d80b0f9 238 Pfam PF00005 ABC transporter 22 164 7.2E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS02430 628a59d26ac536b657c058bc6d80b0f9 238 PANTHER PTHR24220 7 238 5.6E-127 T 22-04-2016 HRM2_RS02430 628a59d26ac536b657c058bc6d80b0f9 238 PANTHER PTHR24220:SF568 7 238 5.6E-127 T 22-04-2016 HRM2_RS02430 628a59d26ac536b657c058bc6d80b0f9 238 PIRSF PIRSF039137 1 237 2.9E-110 T 22-04-2016 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 HRM2_RS03375 e2a4a12b5150eb4760fb7e31f34ef349 202 PANTHER PTHR30335 3 202 1.8E-111 T 22-04-2016 HRM2_RS03375 e2a4a12b5150eb4760fb7e31f34ef349 202 PANTHER PTHR30335:SF1 3 202 1.8E-111 T 22-04-2016 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 HRM2_RS03375 e2a4a12b5150eb4760fb7e31f34ef349 202 PIRSF PIRSF006102 1 202 1.0E-56 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 HRM2_RS03375 e2a4a12b5150eb4760fb7e31f34ef349 202 TIGRFAM TIGR01940 nqrE: NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit 3 200 1.5E-90 T 22-04-2016 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 HRM2_RS03375 e2a4a12b5150eb4760fb7e31f34ef349 202 Hamap MF_00429 Na(+)-translocating NADH-quinone reductase subunit E [nqrE]. 1 202 27.431 T 22-04-2016 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 HRM2_RS03375 e2a4a12b5150eb4760fb7e31f34ef349 202 Pfam PF02508 Rnf-Nqr subunit, membrane protein 5 200 2.2E-55 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 HRM2_RS17385 5a823e03d51aff57331fcab280bdd7c8 200 Pfam PF00430 ATP synthase B/B' CF(0) 51 177 7.5E-17 T 22-04-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 HRM2_RS17385 5a823e03d51aff57331fcab280bdd7c8 200 Hamap MF_01398 ATP synthase subunit b [atpF]. 23 198 11.493 T 22-04-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 HRM2_RS17385 5a823e03d51aff57331fcab280bdd7c8 200 PANTHER PTHR33445 26 198 2.2E-22 T 22-04-2016 HRM2_RS07475 724af1584a4859e8512cff61c407af17 366 PIRSF PIRSF034888 1 364 3.8E-47 T 22-04-2016 IPR014592 Predicted P-loop ATP-binding protein, VCA0200 HRM2_RS07475 724af1584a4859e8512cff61c407af17 366 SUPERFAMILY SSF52540 1 303 4.56E-10 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07475 724af1584a4859e8512cff61c407af17 366 Gene3D G3DSA:3.40.50.300 193 305 4.2E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07475 724af1584a4859e8512cff61c407af17 366 Gene3D G3DSA:3.40.50.300 1 155 4.2E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07475 724af1584a4859e8512cff61c407af17 366 Pfam PF12476 Protein of unknown function (DUF3696) 314 365 2.1E-15 T 22-04-2016 IPR022532 Domain of unknown function DUF3696, C-terminal HRM2_RS07475 724af1584a4859e8512cff61c407af17 366 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 23 303 9.9E-15 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HRM2_RS20030 da5639ee4153492b3bb55f92d281a63d 255 PANTHER PTHR24960 1 172 4.3E-50 T 22-04-2016 HRM2_RS20030 da5639ee4153492b3bb55f92d281a63d 255 PANTHER PTHR24960:SF44 1 172 4.3E-50 T 22-04-2016 HRM2_RS20030 da5639ee4153492b3bb55f92d281a63d 255 Pfam PF12837 4Fe-4S binding domain 7 30 1.0E-6 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS20030 da5639ee4153492b3bb55f92d281a63d 255 SUPERFAMILY SSF54862 4 70 4.79E-16 T 22-04-2016 HRM2_RS20030 da5639ee4153492b3bb55f92d281a63d 255 Gene3D G3DSA:3.30.70.20 4 69 1.7E-15 T 22-04-2016 HRM2_RS21000 1e6aca98682e5ebdac47a678527d89f2 539 SUPERFAMILY SSF54197 378 527 2.65E-8 T 22-04-2016 IPR011146 HIT-like domain GO:0003824 HRM2_RS21000 1e6aca98682e5ebdac47a678527d89f2 539 Gene3D G3DSA:3.30.428.10 379 526 2.5E-8 T 22-04-2016 IPR011146 HIT-like domain GO:0003824 HRM2_RS02230 0bc1097766c665d07009c8a061c3dcf3 145 PANTHER PTHR24960 1 99 4.6E-45 T 22-04-2016 HRM2_RS02230 0bc1097766c665d07009c8a061c3dcf3 145 PANTHER PTHR24960:SF53 1 99 4.6E-45 T 22-04-2016 HRM2_RS02230 0bc1097766c665d07009c8a061c3dcf3 145 Pfam PF12139 Adenosine-5'-phosphosulfate reductase beta subunit 64 135 4.3E-32 T 22-04-2016 IPR022738 Adenylylsulphate reductase, beta subunit, C-terminal HRM2_RS02230 0bc1097766c665d07009c8a061c3dcf3 145 Gene3D G3DSA:3.30.70.20 4 65 2.8E-15 T 22-04-2016 HRM2_RS02230 0bc1097766c665d07009c8a061c3dcf3 145 TIGRFAM TIGR02060 aprB: adenylylsulfate reductase, beta subunit 1 118 1.9E-61 T 22-04-2016 IPR011802 Adenylylsulphate reductase, beta subunit HRM2_RS02230 0bc1097766c665d07009c8a061c3dcf3 145 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 47 58 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS02230 0bc1097766c665d07009c8a061c3dcf3 145 Pfam PF13187 4Fe-4S dicluster domain 9 62 6.0E-10 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS02230 0bc1097766c665d07009c8a061c3dcf3 145 SUPERFAMILY SSF54862 4 107 4.04E-22 T 22-04-2016 HRM2_RS05900 a5a659115b24b03db59a4d95368f34a1 348 Pfam PF08668 HDOD domain 29 228 4.1E-38 T 22-04-2016 IPR013976 Metal-dependent hydrolase HDOD HRM2_RS05900 a5a659115b24b03db59a4d95368f34a1 348 Gene3D G3DSA:1.10.3150.10 13 266 1.4E-50 T 22-04-2016 IPR013976 Metal-dependent hydrolase HDOD HRM2_RS05900 a5a659115b24b03db59a4d95368f34a1 348 SUPERFAMILY SSF109604 21 267 9.26E-47 T 22-04-2016 HRM2_RS05900 a5a659115b24b03db59a4d95368f34a1 348 PANTHER PTHR33525 1 309 2.7E-37 T 22-04-2016 HRM2_RS05900 a5a659115b24b03db59a4d95368f34a1 348 PANTHER PTHR33525:SF3 1 309 2.7E-37 T 22-04-2016 HRM2_RS09250 4268efcbc69511b4a42ab75451bc29aa 340 PANTHER PTHR30004:SF6 2 340 2.0E-150 T 22-04-2016 HRM2_RS09250 4268efcbc69511b4a42ab75451bc29aa 340 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 8 327 5.4E-118 T 22-04-2016 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00244 HRM2_RS09250 4268efcbc69511b4a42ab75451bc29aa 340 PANTHER PTHR30004 2 340 2.0E-150 T 22-04-2016 HRM2_RS09250 4268efcbc69511b4a42ab75451bc29aa 340 SUPERFAMILY SSF53659 6 327 2.43E-109 T 22-04-2016 HRM2_RS09250 4268efcbc69511b4a42ab75451bc29aa 340 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 4 330 35.209 T 22-04-2016 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00244 HRM2_RS09250 4268efcbc69511b4a42ab75451bc29aa 340 Gene3D G3DSA:3.40.718.10 2 327 2.3E-128 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 HRM2_RS09250 4268efcbc69511b4a42ab75451bc29aa 340 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 35 326 2.4E-111 T 22-04-2016 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00244 HRM2_RS08295 e153f14860b7bdaa1b84c4049329e8b2 591 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 354 365 - T 22-04-2016 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 HRM2_RS08295 e153f14860b7bdaa1b84c4049329e8b2 591 Gene3D G3DSA:3.40.50.300 22 137 4.6E-130 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08295 e153f14860b7bdaa1b84c4049329e8b2 591 Gene3D G3DSA:3.40.50.300 274 474 4.6E-130 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08295 e153f14860b7bdaa1b84c4049329e8b2 591 Gene3D G3DSA:3.10.410.10 476 566 6.6E-29 T 22-04-2016 HRM2_RS08295 e153f14860b7bdaa1b84c4049329e8b2 591 PANTHER PTHR10025 9 590 9.9E-291 T 22-04-2016 HRM2_RS08295 e153f14860b7bdaa1b84c4049329e8b2 591 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 7 591 39.178 T 22-04-2016 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 HRM2_RS08295 e153f14860b7bdaa1b84c4049329e8b2 591 SUPERFAMILY SSF52540 10 589 1.55E-203 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08295 e153f14860b7bdaa1b84c4049329e8b2 591 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 112 122 - T 22-04-2016 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 HRM2_RS08295 e153f14860b7bdaa1b84c4049329e8b2 591 Gene3D G3DSA:3.30.1510.10 138 272 3.1E-38 T 22-04-2016 HRM2_RS08295 e153f14860b7bdaa1b84c4049329e8b2 591 Pfam PF01268 Formate--tetrahydrofolate ligase 9 591 2.9E-226 T 22-04-2016 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 HRM2_RS24185 36b276994041ee9196fb8785c6e7e119 220 Pfam PF13401 AAA domain 25 136 5.8E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS24185 36b276994041ee9196fb8785c6e7e119 220 SUPERFAMILY SSF52540 3 210 5.82E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24185 36b276994041ee9196fb8785c6e7e119 220 Gene3D G3DSA:3.40.50.300 22 154 5.0E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19625 d42b012d218dd704b8425ec94b382558 197 Pfam PF08378 Nuclease-related domain 23 136 9.1E-19 T 22-04-2016 IPR011528 Nuclease-related domain, NERD HRM2_RS06065 11e46048325c98ced4f6c55ee1cb3a13 354 PANTHER PTHR22777 1 351 2.0E-125 T 22-04-2016 HRM2_RS06065 11e46048325c98ced4f6c55ee1cb3a13 354 Pfam PF00571 CBS domain 270 319 6.6E-5 T 22-04-2016 IPR000644 CBS domain HRM2_RS06065 11e46048325c98ced4f6c55ee1cb3a13 354 SUPERFAMILY SSF54631 187 320 8.61E-24 T 22-04-2016 HRM2_RS06065 11e46048325c98ced4f6c55ee1cb3a13 354 Pfam PF01595 Domain of unknown function DUF21 10 180 1.9E-26 T 22-04-2016 IPR002550 Domain of unknown function DUF21 HRM2_RS06065 11e46048325c98ced4f6c55ee1cb3a13 354 PANTHER PTHR22777:SF4 1 351 2.0E-125 T 22-04-2016 HRM2_RS06065 11e46048325c98ced4f6c55ee1cb3a13 354 Gene3D G3DSA:3.10.580.10 185 322 4.9E-13 T 22-04-2016 HRM2_RS24030 7604c442d2cc58ede3412d11097b40d1 341 PANTHER PTHR16222:SF15 95 328 4.7E-35 T 22-04-2016 HRM2_RS24030 7604c442d2cc58ede3412d11097b40d1 341 PANTHER PTHR16222:SF15 9 70 4.7E-35 T 22-04-2016 HRM2_RS24030 7604c442d2cc58ede3412d11097b40d1 341 Pfam PF03747 ADP-ribosylglycohydrolase 13 322 2.0E-53 T 22-04-2016 IPR005502 ADP-ribosylation/Crystallin J1 HRM2_RS24030 7604c442d2cc58ede3412d11097b40d1 341 PANTHER PTHR16222 95 328 4.7E-35 T 22-04-2016 HRM2_RS24030 7604c442d2cc58ede3412d11097b40d1 341 PANTHER PTHR16222 9 70 4.7E-35 T 22-04-2016 HRM2_RS24030 7604c442d2cc58ede3412d11097b40d1 341 SUPERFAMILY SSF101478 5 57 2.75E-35 T 22-04-2016 IPR005502 ADP-ribosylation/Crystallin J1 HRM2_RS24030 7604c442d2cc58ede3412d11097b40d1 341 SUPERFAMILY SSF101478 92 336 2.75E-35 T 22-04-2016 IPR005502 ADP-ribosylation/Crystallin J1 HRM2_RS12205 817d19ff23d16e2f3aadf3412ac2545d 253 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 12 220 5.3E-11 T 22-04-2016 HRM2_RS12060 57f899768aface9d2efd495bcff6b130 638 Gene3D G3DSA:3.20.20.190 366 629 4.3E-38 T 22-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 HRM2_RS12060 57f899768aface9d2efd495bcff6b130 638 Gene3D G3DSA:3.20.20.190 295 330 4.3E-38 T 22-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 HRM2_RS12060 57f899768aface9d2efd495bcff6b130 638 PANTHER PTHR13593:SF35 362 580 1.7E-21 T 22-04-2016 HRM2_RS12060 57f899768aface9d2efd495bcff6b130 638 PANTHER PTHR13593:SF35 296 342 1.7E-21 T 22-04-2016 HRM2_RS12060 57f899768aface9d2efd495bcff6b130 638 SUPERFAMILY SSF51695 366 578 2.14E-25 T 22-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 HRM2_RS12060 57f899768aface9d2efd495bcff6b130 638 SUPERFAMILY SSF51695 295 330 2.14E-25 T 22-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 HRM2_RS12060 57f899768aface9d2efd495bcff6b130 638 PANTHER PTHR13593 362 580 1.7E-21 T 22-04-2016 HRM2_RS12060 57f899768aface9d2efd495bcff6b130 638 PANTHER PTHR13593 296 342 1.7E-21 T 22-04-2016 HRM2_RS20375 6e99f09e9d0b043c83b63ac4815403b6 121 Gene3D G3DSA:3.30.70.100 34 85 5.4E-5 T 22-04-2016 HRM2_RS20375 6e99f09e9d0b043c83b63ac4815403b6 121 SUPERFAMILY SSF55008 34 74 7.57E-5 T 22-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 HRM2_RS16305 99e9ec8262c6833bcdd55966fa6b31d6 753 Pfam PF01580 FtsK/SpoIIIE family 388 584 3.8E-62 T 22-04-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 HRM2_RS16305 99e9ec8262c6833bcdd55966fa6b31d6 753 Gene3D G3DSA:3.40.50.300 358 649 3.9E-86 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16305 99e9ec8262c6833bcdd55966fa6b31d6 753 SUPERFAMILY SSF46785 686 750 2.89E-20 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS16305 99e9ec8262c6833bcdd55966fa6b31d6 753 PANTHER PTHR22683:SF41 130 749 1.8E-216 T 22-04-2016 HRM2_RS16305 99e9ec8262c6833bcdd55966fa6b31d6 753 SMART SM00843 686 751 1.7E-32 T 22-04-2016 IPR018541 FtsK gamma domain HRM2_RS16305 99e9ec8262c6833bcdd55966fa6b31d6 753 SUPERFAMILY SSF52540 358 655 8.11E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16305 99e9ec8262c6833bcdd55966fa6b31d6 753 SMART SM00382 420 605 5.8E-5 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS16305 99e9ec8262c6833bcdd55966fa6b31d6 753 PANTHER PTHR22683 130 749 1.8E-216 T 22-04-2016 HRM2_RS16305 99e9ec8262c6833bcdd55966fa6b31d6 753 Pfam PF09397 Ftsk gamma domain 688 748 1.8E-26 T 22-04-2016 IPR018541 FtsK gamma domain HRM2_RS00715 109a15ef452a476fc376d18d758c07bb 405 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 144 4.6E-17 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HRM2_RS00715 109a15ef452a476fc376d18d758c07bb 405 TIGRFAM TIGR03918 GTP_HydF: [FeFe] hydrogenase H-cluster maturation GTPase HydF 5 389 8.0E-142 T 22-04-2016 IPR023873 [FeFe]-hydrogenase H-cluster maturation GTPase HydF HRM2_RS00715 109a15ef452a476fc376d18d758c07bb 405 PANTHER PTHR11649 5 124 3.3E-33 T 22-04-2016 HRM2_RS00715 109a15ef452a476fc376d18d758c07bb 405 Gene3D G3DSA:3.40.50.300 5 141 1.5E-26 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00715 109a15ef452a476fc376d18d758c07bb 405 SUPERFAMILY SSF52540 10 146 1.17E-24 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00715 109a15ef452a476fc376d18d758c07bb 405 PANTHER PTHR11649:SF59 5 124 3.3E-33 T 22-04-2016 HRM2_RS00715 109a15ef452a476fc376d18d758c07bb 405 Pfam PF01926 50S ribosome-binding GTPase 11 124 1.3E-18 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS02105 43ddbc683d757a397531af1b0a5b5ae4 79 Gene3D G3DSA:3.40.640.10 3 47 2.5E-10 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS02105 43ddbc683d757a397531af1b0a5b5ae4 79 SUPERFAMILY SSF53383 3 47 4.77E-10 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS02105 43ddbc683d757a397531af1b0a5b5ae4 79 Pfam PF00202 Aminotransferase class-III 3 47 3.7E-9 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HRM2_RS08240 04367548d95ca76d69e03a06e2d322e7 164 PIRSF PIRSF000216 1 164 3.8E-51 T 22-04-2016 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 HRM2_RS08240 04367548d95ca76d69e03a06e2d322e7 164 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 20 163 2.4E-46 T 22-04-2016 HRM2_RS08240 04367548d95ca76d69e03a06e2d322e7 164 Gene3D G3DSA:3.40.30.10 83 162 2.6E-12 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS08240 04367548d95ca76d69e03a06e2d322e7 164 PANTHER PTHR10371 11 164 1.4E-51 T 22-04-2016 HRM2_RS08240 04367548d95ca76d69e03a06e2d322e7 164 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 121 139 - T 22-04-2016 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 HRM2_RS08240 04367548d95ca76d69e03a06e2d322e7 164 SUPERFAMILY SSF52833 13 163 2.8E-46 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS01735 ec7f4ad57f743033108a23703ed38ab7 391 PANTHER PTHR30483 30 391 5.0E-49 T 22-04-2016 HRM2_RS01735 ec7f4ad57f743033108a23703ed38ab7 391 Pfam PF13458 Periplasmic binding protein 48 367 1.4E-30 T 22-04-2016 IPR028081 Leucine-binding protein domain HRM2_RS01735 ec7f4ad57f743033108a23703ed38ab7 391 PANTHER PTHR30483:SF20 30 391 5.0E-49 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HRM2_RS01735 ec7f4ad57f743033108a23703ed38ab7 391 Gene3D G3DSA:3.40.50.2300 47 246 6.9E-36 T 22-04-2016 HRM2_RS01735 ec7f4ad57f743033108a23703ed38ab7 391 SUPERFAMILY SSF53822 47 388 3.7E-54 T 22-04-2016 IPR028082 Periplasmic binding protein-like I HRM2_RS01735 ec7f4ad57f743033108a23703ed38ab7 391 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 276 294 2.7E-6 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HRM2_RS01735 ec7f4ad57f743033108a23703ed38ab7 391 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 89 107 2.7E-6 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HRM2_RS01735 ec7f4ad57f743033108a23703ed38ab7 391 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 350 365 2.7E-6 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HRM2_RS01735 ec7f4ad57f743033108a23703ed38ab7 391 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 49 65 2.7E-6 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HRM2_RS11750 a891cceb48abf1fb5cdd1ca5819725d5 207 SUPERFAMILY SSF52266 27 205 6.87E-43 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain HRM2_RS11750 a891cceb48abf1fb5cdd1ca5819725d5 207 Gene3D G3DSA:3.40.50.1110 28 205 9.7E-47 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain HRM2_RS11750 a891cceb48abf1fb5cdd1ca5819725d5 207 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 32 194 1.4E-21 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain HRM2_RS11750 a891cceb48abf1fb5cdd1ca5819725d5 207 PANTHER PTHR30383 29 207 1.4E-41 T 22-04-2016 HRM2_RS10325 051c9af1e5c6a33f12804393ce2cde7b 360 PANTHER PTHR30349 58 354 1.2E-32 T 22-04-2016 HRM2_RS10325 051c9af1e5c6a33f12804393ce2cde7b 360 Gene3D G3DSA:1.10.150.130 58 135 8.7E-7 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal HRM2_RS10325 051c9af1e5c6a33f12804393ce2cde7b 360 Gene3D G3DSA:1.10.443.10 163 329 4.7E-34 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS10325 051c9af1e5c6a33f12804393ce2cde7b 360 PANTHER PTHR30349:SF20 58 354 1.2E-32 T 22-04-2016 HRM2_RS10325 051c9af1e5c6a33f12804393ce2cde7b 360 Pfam PF00589 Phage integrase family 164 324 4.7E-24 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS10325 051c9af1e5c6a33f12804393ce2cde7b 360 SUPERFAMILY SSF56349 58 332 5.89E-49 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HRM2_RS13410 129989e5f55537e597adfc83477e6579 516 Pfam PF11849 Domain of unknown function (DUF3369) 150 319 6.2E-42 T 22-04-2016 IPR021800 Domain of unknown function DUF3369 HRM2_RS13410 129989e5f55537e597adfc83477e6579 516 Gene3D G3DSA:3.40.50.2300 26 162 1.2E-14 T 22-04-2016 HRM2_RS13410 129989e5f55537e597adfc83477e6579 516 SMART SM00448 28 150 0.0032 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS13410 129989e5f55537e597adfc83477e6579 516 SMART SM00471 337 474 4.0E-9 T 22-04-2016 IPR003607 HD/PDEase domain HRM2_RS13410 129989e5f55537e597adfc83477e6579 516 Pfam PF01966 HD domain 342 464 2.8E-18 T 22-04-2016 IPR006674 HD domain HRM2_RS13410 129989e5f55537e597adfc83477e6579 516 Pfam PF00072 Response regulator receiver domain 30 149 1.0E-8 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS13410 129989e5f55537e597adfc83477e6579 516 Gene3D G3DSA:1.10.3210.10 323 503 1.1E-25 T 22-04-2016 IPR006674 HD domain HRM2_RS13410 129989e5f55537e597adfc83477e6579 516 SUPERFAMILY SSF109604 329 501 4.85E-40 T 22-04-2016 HRM2_RS13410 129989e5f55537e597adfc83477e6579 516 SUPERFAMILY SSF52172 26 176 1.71E-13 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS02620 4a25fea06431eafb2490921da5581143 192 Pfam PF02834 LigT like Phosphoesterase 105 179 4.5E-6 T 22-04-2016 IPR014051 Phosphoesterase, HXTX HRM2_RS02620 4a25fea06431eafb2490921da5581143 192 Pfam PF02834 LigT like Phosphoesterase 15 97 1.9E-17 T 22-04-2016 IPR014051 Phosphoesterase, HXTX HRM2_RS02620 4a25fea06431eafb2490921da5581143 192 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 8 187 4.2E-42 T 22-04-2016 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 HRM2_RS02620 4a25fea06431eafb2490921da5581143 192 PANTHER PTHR35561 5 192 8.7E-31 T 22-04-2016 HRM2_RS02620 4a25fea06431eafb2490921da5581143 192 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 7 190 22.507 T 22-04-2016 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 HRM2_RS02620 4a25fea06431eafb2490921da5581143 192 PANTHER PTHR35561:SF1 5 192 8.7E-31 T 22-04-2016 HRM2_RS02620 4a25fea06431eafb2490921da5581143 192 Gene3D G3DSA:3.90.1140.10 8 190 3.8E-45 T 22-04-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase HRM2_RS02620 4a25fea06431eafb2490921da5581143 192 SUPERFAMILY SSF55144 8 190 3.84E-39 T 22-04-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase HRM2_RS01605 9a8828e4fd1b98bd3a5b2d33300765d9 1001 Gene3D G3DSA:3.30.1490.20 428 607 5.0E-22 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HRM2_RS01605 9a8828e4fd1b98bd3a5b2d33300765d9 1001 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 436 815 2.0E-37 T 22-04-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 HRM2_RS01605 9a8828e4fd1b98bd3a5b2d33300765d9 1001 Gene3D G3DSA:3.40.50.2300 217 314 1.4E-5 T 22-04-2016 HRM2_RS01605 9a8828e4fd1b98bd3a5b2d33300765d9 1001 SUPERFAMILY SSF56059 754 811 2.59E-21 T 22-04-2016 HRM2_RS01605 9a8828e4fd1b98bd3a5b2d33300765d9 1001 SUPERFAMILY SSF56059 432 666 2.59E-21 T 22-04-2016 HRM2_RS01605 9a8828e4fd1b98bd3a5b2d33300765d9 1001 Gene3D G3DSA:3.40.50.2300 66 121 2.0E-5 T 22-04-2016 HRM2_RS01605 9a8828e4fd1b98bd3a5b2d33300765d9 1001 SUPERFAMILY SSF52172 67 171 8.94E-7 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS07370 5b9ca55c4af0d2299e47faa65287e4ca 1107 SUPERFAMILY SSF52540 554 582 6.58E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07370 5b9ca55c4af0d2299e47faa65287e4ca 1107 SUPERFAMILY SSF52540 947 1082 6.58E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07370 5b9ca55c4af0d2299e47faa65287e4ca 1107 SUPERFAMILY SSF52540 742 920 6.58E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07370 5b9ca55c4af0d2299e47faa65287e4ca 1107 SUPERFAMILY SSF52540 420 494 6.58E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07370 5b9ca55c4af0d2299e47faa65287e4ca 1107 Gene3D G3DSA:3.40.50.300 781 892 3.8E-39 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07370 5b9ca55c4af0d2299e47faa65287e4ca 1107 Gene3D G3DSA:3.40.50.300 402 564 3.8E-39 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07370 5b9ca55c4af0d2299e47faa65287e4ca 1107 Pfam PF13087 AAA domain 845 1077 1.3E-36 T 22-04-2016 HRM2_RS07370 5b9ca55c4af0d2299e47faa65287e4ca 1107 PANTHER PTHR10887 370 507 1.5E-70 T 22-04-2016 HRM2_RS07370 5b9ca55c4af0d2299e47faa65287e4ca 1107 PANTHER PTHR10887 742 995 1.5E-70 T 22-04-2016 HRM2_RS07370 5b9ca55c4af0d2299e47faa65287e4ca 1107 PANTHER PTHR10887 1011 1079 1.5E-70 T 22-04-2016 HRM2_RS07370 5b9ca55c4af0d2299e47faa65287e4ca 1107 Gene3D G3DSA:3.40.50.300 933 1076 1.9E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07370 5b9ca55c4af0d2299e47faa65287e4ca 1107 Pfam PF13086 AAA domain 424 822 5.0E-31 T 22-04-2016 HRM2_RS15565 1210b379e82ed4c5646519fc82cfaa26 490 Gene3D G3DSA:3.90.1300.10 2 482 8.2E-184 T 22-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HRM2_RS15565 1210b379e82ed4c5646519fc82cfaa26 490 ProSitePatterns PS00571 Amidases signature. 151 182 - T 22-04-2016 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HRM2_RS15565 1210b379e82ed4c5646519fc82cfaa26 490 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 482 91.494 T 22-04-2016 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HRM2_RS15565 1210b379e82ed4c5646519fc82cfaa26 490 PANTHER PTHR11895 2 488 1.1E-214 T 22-04-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HRM2_RS15565 1210b379e82ed4c5646519fc82cfaa26 490 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 13 480 1.8E-186 T 22-04-2016 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HRM2_RS15565 1210b379e82ed4c5646519fc82cfaa26 490 Pfam PF01425 Amidase 25 471 4.7E-162 T 22-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HRM2_RS15565 1210b379e82ed4c5646519fc82cfaa26 490 PANTHER PTHR11895:SF7 2 488 1.1E-214 T 22-04-2016 HRM2_RS15565 1210b379e82ed4c5646519fc82cfaa26 490 SUPERFAMILY SSF75304 1 484 3.4E-165 T 22-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HRM2_RS12040 bf7bd0e4882cc242862134e1a4ad7ff9 381 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 65 326 4.4E-28 T 22-04-2016 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 HRM2_RS12040 bf7bd0e4882cc242862134e1a4ad7ff9 381 PANTHER PTHR33376 16 367 2.4E-28 T 22-04-2016 HRM2_RS07140 118d39420ede92971813f2665a89871a 418 Gene3D G3DSA:3.30.70.20 232 261 4.1E-4 T 22-04-2016 HRM2_RS07140 118d39420ede92971813f2665a89871a 418 Gene3D G3DSA:3.30.70.20 158 178 4.1E-4 T 22-04-2016 HRM2_RS07140 118d39420ede92971813f2665a89871a 418 PANTHER PTHR10742 11 137 1.6E-22 T 22-04-2016 HRM2_RS07140 118d39420ede92971813f2665a89871a 418 PANTHER PTHR10742 158 353 1.6E-22 T 22-04-2016 HRM2_RS07140 118d39420ede92971813f2665a89871a 418 Gene3D G3DSA:3.50.50.60 9 110 4.3E-24 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS07140 118d39420ede92971813f2665a89871a 418 Gene3D G3DSA:3.50.50.60 179 219 4.3E-24 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS07140 118d39420ede92971813f2665a89871a 418 Gene3D G3DSA:3.50.50.60 364 408 4.3E-24 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS07140 118d39420ede92971813f2665a89871a 418 PANTHER PTHR10742:SF263 11 137 1.6E-22 T 22-04-2016 HRM2_RS07140 118d39420ede92971813f2665a89871a 418 PANTHER PTHR10742:SF263 158 353 1.6E-22 T 22-04-2016 HRM2_RS07140 118d39420ede92971813f2665a89871a 418 Pfam PF12831 FAD dependent oxidoreductase 11 49 1.0E-9 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS07140 118d39420ede92971813f2665a89871a 418 SUPERFAMILY SSF54862 50 173 1.62E-16 T 22-04-2016 HRM2_RS07140 118d39420ede92971813f2665a89871a 418 Gene3D G3DSA:3.30.70.20 113 157 9.0E-15 T 22-04-2016 HRM2_RS07140 118d39420ede92971813f2665a89871a 418 Pfam PF13187 4Fe-4S dicluster domain 118 168 3.3E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS07140 118d39420ede92971813f2665a89871a 418 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 153 164 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS07140 118d39420ede92971813f2665a89871a 418 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 119 130 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS07140 118d39420ede92971813f2665a89871a 418 SUPERFAMILY SSF51905 5 78 1.49E-24 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS07140 118d39420ede92971813f2665a89871a 418 SUPERFAMILY SSF51905 157 376 1.49E-24 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS10955 c8af2c3ea91ed537486acf1b046b53ba 306 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 6 296 29.101 T 22-04-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781 HRM2_RS10955 c8af2c3ea91ed537486acf1b046b53ba 306 Gene3D G3DSA:3.40.50.300 2 168 5.0E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10955 c8af2c3ea91ed537486acf1b046b53ba 306 Pfam PF01715 IPP transferase 39 282 3.0E-76 T 22-04-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781 HRM2_RS10955 c8af2c3ea91ed537486acf1b046b53ba 306 Gene3D G3DSA:1.10.287.890 199 280 5.6E-32 T 22-04-2016 HRM2_RS10955 c8af2c3ea91ed537486acf1b046b53ba 306 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 6 289 7.6E-90 T 22-04-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781 HRM2_RS10955 c8af2c3ea91ed537486acf1b046b53ba 306 SUPERFAMILY SSF52540 6 148 2.92E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10955 c8af2c3ea91ed537486acf1b046b53ba 306 SUPERFAMILY SSF52540 5 38 3.72E-5 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10955 c8af2c3ea91ed537486acf1b046b53ba 306 SUPERFAMILY SSF52540 161 225 3.72E-5 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10955 c8af2c3ea91ed537486acf1b046b53ba 306 PANTHER PTHR11088 3 286 9.8E-104 T 22-04-2016 HRM2_RS23065 e4cb887ddb05e994eea348739cac025d 736 PANTHER PTHR11573:SF3 8 736 0.0 T 22-04-2016 HRM2_RS23065 e4cb887ddb05e994eea348739cac025d 736 PANTHER PTHR11573 8 736 0.0 T 22-04-2016 HRM2_RS23065 e4cb887ddb05e994eea348739cac025d 736 Pfam PF02867 Ribonucleotide reductase, barrel domain 93 563 1.9E-151 T 22-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HRM2_RS23065 e4cb887ddb05e994eea348739cac025d 736 SUPERFAMILY SSF51998 499 575 1.74E-147 T 22-04-2016 HRM2_RS23065 e4cb887ddb05e994eea348739cac025d 736 SUPERFAMILY SSF51998 92 467 1.74E-147 T 22-04-2016 HRM2_RS23065 e4cb887ddb05e994eea348739cac025d 736 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 14 90 7.3E-24 T 22-04-2016 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 HRM2_RS23065 e4cb887ddb05e994eea348739cac025d 736 SUPERFAMILY SSF48168 17 91 8.63E-15 T 22-04-2016 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 HRM2_RS23065 e4cb887ddb05e994eea348739cac025d 736 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 18 573 4.0E-213 T 22-04-2016 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HRM2_RS23065 e4cb887ddb05e994eea348739cac025d 736 Gene3D G3DSA:3.20.70.20 9 461 3.2E-170 T 22-04-2016 HRM2_RS23065 e4cb887ddb05e994eea348739cac025d 736 Gene3D G3DSA:3.20.70.20 522 568 3.2E-170 T 22-04-2016 HRM2_RS23065 e4cb887ddb05e994eea348739cac025d 736 PRINTS PR01183 Ribonucleotide reductase large chain signature 309 332 5.6E-30 T 22-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HRM2_RS23065 e4cb887ddb05e994eea348739cac025d 736 PRINTS PR01183 Ribonucleotide reductase large chain signature 347 369 5.6E-30 T 22-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HRM2_RS23065 e4cb887ddb05e994eea348739cac025d 736 PRINTS PR01183 Ribonucleotide reductase large chain signature 168 187 5.6E-30 T 22-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HRM2_RS23065 e4cb887ddb05e994eea348739cac025d 736 PRINTS PR01183 Ribonucleotide reductase large chain signature 416 443 5.6E-30 T 22-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HRM2_RS23065 e4cb887ddb05e994eea348739cac025d 736 PRINTS PR01183 Ribonucleotide reductase large chain signature 375 398 5.6E-30 T 22-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HRM2_RS08140 33e49b9ab1ab7a9d5bd15dee527b941a 228 Gene3D G3DSA:1.10.10.10 2 54 3.9E-6 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS08140 33e49b9ab1ab7a9d5bd15dee527b941a 228 SUPERFAMILY SSF46955 1 53 1.01E-9 T 22-04-2016 IPR009061 Putative DNA-binding domain HRM2_RS08140 33e49b9ab1ab7a9d5bd15dee527b941a 228 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 82 218 3.6E-22 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HRM2_RS08140 33e49b9ab1ab7a9d5bd15dee527b941a 228 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 3 49 3.6E-9 T 22-04-2016 IPR010093 SinI-like, DNA-binding domain GO:0003677 HRM2_RS08140 33e49b9ab1ab7a9d5bd15dee527b941a 228 Pfam PF12728 Helix-turn-helix domain 3 52 4.7E-7 T 22-04-2016 HRM2_RS08140 33e49b9ab1ab7a9d5bd15dee527b941a 228 SUPERFAMILY SSF55804 80 218 1.7E-25 T 22-04-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 HRM2_RS08140 33e49b9ab1ab7a9d5bd15dee527b941a 228 Gene3D G3DSA:3.40.930.10 82 220 1.2E-26 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HRM2_RS08140 33e49b9ab1ab7a9d5bd15dee527b941a 228 PANTHER PTHR30505 73 227 7.5E-30 T 22-04-2016 HRM2_RS08140 33e49b9ab1ab7a9d5bd15dee527b941a 228 PANTHER PTHR30505:SF6 73 227 7.5E-30 T 22-04-2016 HRM2_RS00900 cb38bbae6990d9ca2578d5967d525b9a 384 PANTHER PTHR41771 10 384 7.0E-47 T 22-04-2016 HRM2_RS00900 cb38bbae6990d9ca2578d5967d525b9a 384 PANTHER PTHR41771:SF1 10 384 7.0E-47 T 22-04-2016 HRM2_RS00900 cb38bbae6990d9ca2578d5967d525b9a 384 Pfam PF07907 YibE/F-like protein 129 368 4.3E-72 T 22-04-2016 IPR012507 YibE/F-like HRM2_RS03390 eff5f819f01c3c040baa62ae03a418a1 203 PANTHER PTHR23029 2 167 8.5E-41 T 22-04-2016 HRM2_RS03390 eff5f819f01c3c040baa62ae03a418a1 203 SUPERFAMILY SSF53254 2 184 8.51E-51 T 22-04-2016 IPR029033 Histidine phosphatase superfamily HRM2_RS03390 eff5f819f01c3c040baa62ae03a418a1 203 TIGRFAM TIGR03162 ribazole_cobC: alpha-ribazole phosphatase 2 179 2.2E-51 T 22-04-2016 IPR017578 Alpha-ribazole phosphatase, CobC GO:0009236|GO:0043755 KEGG: 00860+3.1.3.73|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 HRM2_RS03390 eff5f819f01c3c040baa62ae03a418a1 203 PIRSF PIRSF000709 1 181 2.1E-25 T 22-04-2016 HRM2_RS03390 eff5f819f01c3c040baa62ae03a418a1 203 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 2 186 4.7E-52 T 22-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 HRM2_RS03390 eff5f819f01c3c040baa62ae03a418a1 203 Gene3D G3DSA:3.40.50.1240 2 181 9.4E-52 T 22-04-2016 IPR029033 Histidine phosphatase superfamily HRM2_RS03390 eff5f819f01c3c040baa62ae03a418a1 203 SMART SM00855 1 154 9.0E-18 T 22-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 HRM2_RS03390 eff5f819f01c3c040baa62ae03a418a1 203 PANTHER PTHR23029:SF1 2 167 8.5E-41 T 22-04-2016 HRM2_RS06855 df919506cb92ad7ea74f89e79fa08f57 473 PANTHER PTHR34595:SF3 3 473 2.3E-290 T 22-04-2016 HRM2_RS06855 df919506cb92ad7ea74f89e79fa08f57 473 SUPERFAMILY SSF56059 27 216 2.28E-60 T 22-04-2016 HRM2_RS06855 df919506cb92ad7ea74f89e79fa08f57 473 SUPERFAMILY SSF56059 323 468 2.28E-60 T 22-04-2016 HRM2_RS06855 df919506cb92ad7ea74f89e79fa08f57 473 PANTHER PTHR34595 3 473 2.3E-290 T 22-04-2016 HRM2_RS06855 df919506cb92ad7ea74f89e79fa08f57 473 PIRSF PIRSF005522 1 473 8.8E-227 T 22-04-2016 IPR016450 Uncharacterised conserved protein UCP005522 HRM2_RS06855 df919506cb92ad7ea74f89e79fa08f57 473 Pfam PF14403 Circularly permuted ATP-grasp type 2 78 453 1.9E-167 T 22-04-2016 IPR025841 Circularly permuted ATP-grasp type 2 HRM2_RS23150 8679cdf195344eefa1cfbe539bf7a0b2 509 Gene3D G3DSA:3.30.565.10 358 505 8.1E-42 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS23150 8679cdf195344eefa1cfbe539bf7a0b2 509 Pfam PF08448 PAS fold 142 256 1.1E-14 T 22-04-2016 IPR013656 PAS fold-4 HRM2_RS23150 8679cdf195344eefa1cfbe539bf7a0b2 509 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 399 505 1.0E-20 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS23150 8679cdf195344eefa1cfbe539bf7a0b2 509 Gene3D G3DSA:3.30.450.20 145 254 3.0E-14 T 22-04-2016 HRM2_RS23150 8679cdf195344eefa1cfbe539bf7a0b2 509 Pfam PF00512 His Kinase A (phospho-acceptor) domain 283 353 3.2E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS23150 8679cdf195344eefa1cfbe539bf7a0b2 509 PANTHER PTHR24423 139 254 3.5E-74 T 22-04-2016 HRM2_RS23150 8679cdf195344eefa1cfbe539bf7a0b2 509 PANTHER PTHR24423 271 505 3.5E-74 T 22-04-2016 HRM2_RS23150 8679cdf195344eefa1cfbe539bf7a0b2 509 SUPERFAMILY SSF55785 128 249 2.44E-14 T 22-04-2016 IPR000014 PAS domain HRM2_RS23150 8679cdf195344eefa1cfbe539bf7a0b2 509 Gene3D G3DSA:1.10.287.130 283 352 6.1E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS23150 8679cdf195344eefa1cfbe539bf7a0b2 509 SUPERFAMILY SSF51735 15 106 3.94E-9 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS23150 8679cdf195344eefa1cfbe539bf7a0b2 509 SMART SM00388 283 356 6.3E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS23150 8679cdf195344eefa1cfbe539bf7a0b2 509 SUPERFAMILY SSF47384 278 352 5.3E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS23150 8679cdf195344eefa1cfbe539bf7a0b2 509 Gene3D G3DSA:3.40.50.720 15 111 6.7E-6 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS23150 8679cdf195344eefa1cfbe539bf7a0b2 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 464 5.1E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS23150 8679cdf195344eefa1cfbe539bf7a0b2 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 491 504 5.1E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS23150 8679cdf195344eefa1cfbe539bf7a0b2 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 467 485 5.1E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS23150 8679cdf195344eefa1cfbe539bf7a0b2 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 436 450 5.1E-17 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS23150 8679cdf195344eefa1cfbe539bf7a0b2 509 SMART SM00387 398 507 8.7E-33 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS23150 8679cdf195344eefa1cfbe539bf7a0b2 509 SUPERFAMILY SSF55874 346 505 3.01E-41 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS02870 3825124efdfa4b798a0878ca70e7035e 683 Pfam PF02233 NAD(P) transhydrogenase beta subunit 515 676 2.7E-71 T 22-04-2016 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 HRM2_RS02870 3825124efdfa4b798a0878ca70e7035e 683 Pfam PF02233 NAD(P) transhydrogenase beta subunit 18 480 7.6E-143 T 22-04-2016 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 HRM2_RS02870 3825124efdfa4b798a0878ca70e7035e 683 PANTHER PTHR10160 11 489 1.7E-135 T 22-04-2016 HRM2_RS02870 3825124efdfa4b798a0878ca70e7035e 683 SUPERFAMILY SSF52467 513 681 2.05E-55 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HRM2_RS02870 3825124efdfa4b798a0878ca70e7035e 683 Gene3D G3DSA:3.40.50.1220 313 485 1.8E-72 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HRM2_RS02870 3825124efdfa4b798a0878ca70e7035e 683 Gene3D G3DSA:3.40.50.1220 514 681 1.9E-68 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HRM2_RS02870 3825124efdfa4b798a0878ca70e7035e 683 SUPERFAMILY SSF52467 314 485 2.1E-58 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HRM2_RS02870 3825124efdfa4b798a0878ca70e7035e 683 PANTHER PTHR10160:SF24 11 489 1.7E-135 T 22-04-2016 HRM2_RS17590 46a7e7e174da13e1fc4c972466a1ac61 131 Gene3D G3DSA:3.30.450.30 1 126 2.5E-34 T 22-04-2016 HRM2_RS17590 46a7e7e174da13e1fc4c972466a1ac61 131 SMART SM00960 10 100 0.0076 T 22-04-2016 IPR004942 Roadblock/LAMTOR2 domain HRM2_RS17590 46a7e7e174da13e1fc4c972466a1ac61 131 Pfam PF03259 Roadblock/LC7 domain 22 98 6.2E-7 T 22-04-2016 IPR004942 Roadblock/LAMTOR2 domain HRM2_RS17590 46a7e7e174da13e1fc4c972466a1ac61 131 SUPERFAMILY SSF103196 2 126 4.97E-24 T 22-04-2016 HRM2_RS08515 80cd91abafb47d2db0942c09a1a0f22e 240 PANTHER PTHR21499:SF23 5 237 1.2E-108 T 22-04-2016 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 HRM2_RS08515 80cd91abafb47d2db0942c09a1a0f22e 240 Gene3D G3DSA:3.40.1160.10 5 239 5.9E-83 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HRM2_RS08515 80cd91abafb47d2db0942c09a1a0f22e 240 PIRSF PIRSF005650 4 240 1.2E-88 T 22-04-2016 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 HRM2_RS08515 80cd91abafb47d2db0942c09a1a0f22e 240 SUPERFAMILY SSF53633 7 238 2.49E-70 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HRM2_RS08515 80cd91abafb47d2db0942c09a1a0f22e 240 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 8 237 2.1E-94 T 22-04-2016 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 HRM2_RS08515 80cd91abafb47d2db0942c09a1a0f22e 240 PANTHER PTHR21499 5 237 1.2E-108 T 22-04-2016 HRM2_RS08515 80cd91abafb47d2db0942c09a1a0f22e 240 Pfam PF00696 Amino acid kinase family 9 217 1.1E-25 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HRM2_RS08515 80cd91abafb47d2db0942c09a1a0f22e 240 Hamap MF_01220_B Uridylate kinase [pyrH]. 5 238 42.609 T 22-04-2016 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 HRM2_RS25170 286a8bcae5363c61317c0a23b110ffca 742 Pfam PF00158 Sigma-54 interaction domain 426 588 4.9E-55 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS25170 286a8bcae5363c61317c0a23b110ffca 742 PANTHER PTHR32071 342 742 8.8E-103 T 22-04-2016 HRM2_RS25170 286a8bcae5363c61317c0a23b110ffca 742 SMART SM00382 447 588 3.2E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS25170 286a8bcae5363c61317c0a23b110ffca 742 Gene3D G3DSA:1.10.10.60 650 742 2.6E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS25170 286a8bcae5363c61317c0a23b110ffca 742 Pfam PF02954 Bacterial regulatory protein, Fis family 709 733 3.5E-5 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS25170 286a8bcae5363c61317c0a23b110ffca 742 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 723 742 7.6E-7 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS25170 286a8bcae5363c61317c0a23b110ffca 742 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 706 723 7.6E-7 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS25170 286a8bcae5363c61317c0a23b110ffca 742 Gene3D G3DSA:1.10.8.60 598 649 1.2E-13 T 22-04-2016 HRM2_RS25170 286a8bcae5363c61317c0a23b110ffca 742 Gene3D G3DSA:3.40.50.300 421 595 8.3E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS25170 286a8bcae5363c61317c0a23b110ffca 742 SUPERFAMILY SSF52540 425 662 7.1E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS25170 286a8bcae5363c61317c0a23b110ffca 742 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 511 526 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS00090 25ea561f45d5dd4fa28a7312512a1fb9 368 Gene3D G3DSA:3.30.2110.10 9 186 8.6E-55 T 22-04-2016 HRM2_RS00090 25ea561f45d5dd4fa28a7312512a1fb9 368 SUPERFAMILY SSF111342 3 289 4.45E-77 T 22-04-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 HRM2_RS00090 25ea561f45d5dd4fa28a7312512a1fb9 368 PIRSF PIRSF026782 2 367 2.4E-108 T 22-04-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 HRM2_RS00090 25ea561f45d5dd4fa28a7312512a1fb9 368 Pfam PF01888 CbiD 7 273 2.7E-88 T 22-04-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 HRM2_RS00090 25ea561f45d5dd4fa28a7312512a1fb9 368 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 6 363 26.975 T 22-04-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 HRM2_RS00090 25ea561f45d5dd4fa28a7312512a1fb9 368 PANTHER PTHR35863:SF1 1 364 1.2E-88 T 22-04-2016 HRM2_RS00090 25ea561f45d5dd4fa28a7312512a1fb9 368 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 13 359 5.1E-65 T 22-04-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 HRM2_RS00090 25ea561f45d5dd4fa28a7312512a1fb9 368 PANTHER PTHR35863 1 364 1.2E-88 T 22-04-2016 HRM2_RS01725 5cdfb81eca85f7cac4ff263beab5fe75 1043 Gene3D G3DSA:3.40.50.720 663 767 7.2E-24 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS01725 5cdfb81eca85f7cac4ff263beab5fe75 1043 Gene3D G3DSA:3.40.50.720 805 883 7.2E-24 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS01725 5cdfb81eca85f7cac4ff263beab5fe75 1043 SMART SM00839 663 946 1.6E-4 T 22-04-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 HRM2_RS01725 5cdfb81eca85f7cac4ff263beab5fe75 1043 PANTHER PTHR11606:SF9 669 1026 1.9E-76 T 22-04-2016 HRM2_RS01725 5cdfb81eca85f7cac4ff263beab5fe75 1043 PANTHER PTHR11606:SF9 288 620 1.9E-76 T 22-04-2016 HRM2_RS01725 5cdfb81eca85f7cac4ff263beab5fe75 1043 SUPERFAMILY SSF51735 803 894 6.19E-13 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS01725 5cdfb81eca85f7cac4ff263beab5fe75 1043 SUPERFAMILY SSF51735 669 765 6.19E-13 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS01725 5cdfb81eca85f7cac4ff263beab5fe75 1043 PANTHER PTHR11606 669 1026 1.9E-76 T 22-04-2016 HRM2_RS01725 5cdfb81eca85f7cac4ff263beab5fe75 1043 PANTHER PTHR11606 288 620 1.9E-76 T 22-04-2016 HRM2_RS01725 5cdfb81eca85f7cac4ff263beab5fe75 1043 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 662 879 1.0E-21 T 22-04-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 HRM2_RS01725 5cdfb81eca85f7cac4ff263beab5fe75 1043 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 356 492 1.7E-13 T 22-04-2016 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 HRM2_RS00510 f35263ce42b564887866fd312d104db8 261 SUPERFAMILY SSF52540 1 228 2.9E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00510 f35263ce42b564887866fd312d104db8 261 Gene3D G3DSA:3.40.50.300 1 240 7.5E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00510 f35263ce42b564887866fd312d104db8 261 PANTHER PTHR24220:SF73 3 242 1.4E-70 T 22-04-2016 HRM2_RS00510 f35263ce42b564887866fd312d104db8 261 PANTHER PTHR24220 3 242 1.4E-70 T 22-04-2016 HRM2_RS00510 f35263ce42b564887866fd312d104db8 261 SMART SM00382 29 216 6.7E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS00510 f35263ce42b564887866fd312d104db8 261 Pfam PF00005 ABC transporter 29 166 1.6E-25 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS00510 f35263ce42b564887866fd312d104db8 261 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS00690 758b992f1b584dcac392c392f6edc4e1 295 SUPERFAMILY SSF103473 147 207 5.75E-5 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS00690 758b992f1b584dcac392c392f6edc4e1 295 SUPERFAMILY SSF103473 19 70 5.75E-5 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS00690 758b992f1b584dcac392c392f6edc4e1 295 Gene3D G3DSA:3.30.2010.10 68 155 4.5E-22 T 22-04-2016 HRM2_RS00690 758b992f1b584dcac392c392f6edc4e1 295 PANTHER PTHR10120:SF19 11 279 5.6E-55 T 22-04-2016 HRM2_RS00690 758b992f1b584dcac392c392f6edc4e1 295 PANTHER PTHR10120 11 279 5.6E-55 T 22-04-2016 HRM2_RS00690 758b992f1b584dcac392c392f6edc4e1 295 Pfam PF01435 Peptidase family M48 79 277 1.1E-26 T 22-04-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 HRM2_RS05765 ae4b64948582b9fc271ee4d74317f97c 289 PIRSF PIRSF006483 3 288 4.8E-70 T 22-04-2016 IPR003740 Uncharacterised membrane protein YitT HRM2_RS05765 ae4b64948582b9fc271ee4d74317f97c 289 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 18 218 4.2E-51 T 22-04-2016 IPR003740 Uncharacterised membrane protein YitT HRM2_RS05765 ae4b64948582b9fc271ee4d74317f97c 289 PANTHER PTHR33545 1 289 6.5E-70 T 22-04-2016 HRM2_RS05765 ae4b64948582b9fc271ee4d74317f97c 289 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 226 280 8.9E-18 T 22-04-2016 IPR019264 Domain of unknown function DUF2179 HRM2_RS01710 c064f67d140f075b18a9a430bb539192 563 PANTHER PTHR10192:SF13 363 542 1.5E-41 T 22-04-2016 HRM2_RS01710 c064f67d140f075b18a9a430bb539192 563 PANTHER PTHR10192 363 542 1.5E-41 T 22-04-2016 HRM2_RS01710 c064f67d140f075b18a9a430bb539192 563 SUPERFAMILY SSF53218 394 560 3.27E-28 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS01710 c064f67d140f075b18a9a430bb539192 563 SMART SM00852 398 530 9.8E-19 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS01710 c064f67d140f075b18a9a430bb539192 563 Gene3D G3DSA:3.40.980.10 381 530 2.0E-28 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS01710 c064f67d140f075b18a9a430bb539192 563 Gene3D G3DSA:3.30.1330.20 47 134 1.6E-20 T 22-04-2016 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain HRM2_RS01710 c064f67d140f075b18a9a430bb539192 563 Pfam PF02663 FmdE, Molybdenum formylmethanofuran dehydrogenase operon 40 163 1.7E-29 T 22-04-2016 IPR003814 Formylmethanofuran dehydrogenase, subunit E domain HRM2_RS01710 c064f67d140f075b18a9a430bb539192 563 SUPERFAMILY SSF143555 28 169 3.92E-43 T 22-04-2016 HRM2_RS01710 c064f67d140f075b18a9a430bb539192 563 Pfam PF00994 Probable molybdopterin binding domain 398 492 3.3E-18 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS13405 d4d0b6a22e82013bc3599d565f0f3e31 225 Pfam PF11813 Protein of unknown function (DUF3334) 6 222 5.7E-86 T 22-04-2016 IPR024513 Protein of unknown function DUF3334 HRM2_RS13405 d4d0b6a22e82013bc3599d565f0f3e31 225 Gene3D G3DSA:3.40.1550.10 16 175 1.2E-15 T 22-04-2016 IPR028976 CheC-like domain HRM2_RS13405 d4d0b6a22e82013bc3599d565f0f3e31 225 SUPERFAMILY SSF103039 12 168 1.07E-21 T 22-04-2016 IPR028976 CheC-like domain HRM2_RS20015 11e81f4482217f7784ffc8db9975c0f5 276 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 273 16.878 T 22-04-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 HRM2_RS20015 11e81f4482217f7784ffc8db9975c0f5 276 PANTHER PTHR30622 1 275 9.1E-84 T 22-04-2016 HRM2_RS20015 11e81f4482217f7784ffc8db9975c0f5 276 Pfam PF02673 Bacitracin resistance protein BacA 7 268 3.4E-68 T 22-04-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 HRM2_RS21545 13183264250caa5fe7d9e07689479d90 274 Pfam PF00753 Metallo-beta-lactamase superfamily 32 96 1.0E-8 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS21545 13183264250caa5fe7d9e07689479d90 274 Gene3D G3DSA:3.60.15.10 5 261 3.1E-26 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS21545 13183264250caa5fe7d9e07689479d90 274 PANTHER PTHR13754:SF13 4 259 7.1E-67 T 22-04-2016 HRM2_RS21545 13183264250caa5fe7d9e07689479d90 274 PANTHER PTHR13754 4 259 7.1E-67 T 22-04-2016 HRM2_RS21545 13183264250caa5fe7d9e07689479d90 274 SUPERFAMILY SSF56281 25 263 3.93E-34 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS02905 838ad7ba9606676313de331cfb50d12d 272 SUPERFAMILY SSF53474 31 264 6.32E-36 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS02905 838ad7ba9606676313de331cfb50d12d 272 PANTHER PTHR10992 35 266 1.7E-31 T 22-04-2016 HRM2_RS02905 838ad7ba9606676313de331cfb50d12d 272 PANTHER PTHR10992:SF832 35 266 1.7E-31 T 22-04-2016 HRM2_RS02905 838ad7ba9606676313de331cfb50d12d 272 Gene3D G3DSA:3.40.50.1820 34 267 2.5E-33 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS02905 838ad7ba9606676313de331cfb50d12d 272 Pfam PF12697 Alpha/beta hydrolase family 36 255 1.8E-14 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HRM2_RS22970 f9acd3260e6a0f6af2b76e6eae3098ee 196 SUPERFAMILY SSF103088 88 195 7.46E-23 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS22970 f9acd3260e6a0f6af2b76e6eae3098ee 196 Pfam PF00691 OmpA family 94 189 9.4E-14 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS22970 f9acd3260e6a0f6af2b76e6eae3098ee 196 PANTHER PTHR30128 54 196 4.4E-15 T 22-04-2016 HRM2_RS22970 f9acd3260e6a0f6af2b76e6eae3098ee 196 Gene3D G3DSA:3.30.1330.60 93 195 7.2E-22 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS22970 f9acd3260e6a0f6af2b76e6eae3098ee 196 PANTHER PTHR30128:SF11 54 196 4.4E-15 T 22-04-2016 HRM2_RS22970 f9acd3260e6a0f6af2b76e6eae3098ee 196 PRINTS PR01021 OMPA domain signature 125 140 4.8E-7 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 HRM2_RS22970 f9acd3260e6a0f6af2b76e6eae3098ee 196 PRINTS PR01021 OMPA domain signature 95 117 4.8E-7 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 HRM2_RS22970 f9acd3260e6a0f6af2b76e6eae3098ee 196 PRINTS PR01021 OMPA domain signature 140 156 4.8E-7 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 HRM2_RS11805 451feed9c80b40709495e3e724ada15d 297 PRINTS PR01438 Universal stress protein signature 135 157 3.0E-5 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS11805 451feed9c80b40709495e3e724ada15d 297 PRINTS PR01438 Universal stress protein signature 5 23 3.0E-5 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS11805 451feed9c80b40709495e3e724ada15d 297 PRINTS PR01438 Universal stress protein signature 117 129 3.0E-5 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS11805 451feed9c80b40709495e3e724ada15d 297 Gene3D G3DSA:3.40.50.620 161 293 4.3E-11 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS11805 451feed9c80b40709495e3e724ada15d 297 Pfam PF00582 Universal stress protein family 164 292 1.0E-8 T 22-04-2016 IPR006016 UspA GO:0006950 HRM2_RS11805 451feed9c80b40709495e3e724ada15d 297 Pfam PF00582 Universal stress protein family 7 157 4.7E-7 T 22-04-2016 IPR006016 UspA GO:0006950 HRM2_RS11805 451feed9c80b40709495e3e724ada15d 297 SUPERFAMILY SSF52402 7 157 1.09E-13 T 22-04-2016 HRM2_RS11805 451feed9c80b40709495e3e724ada15d 297 Gene3D G3DSA:3.40.50.620 7 157 2.6E-15 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS11805 451feed9c80b40709495e3e724ada15d 297 SUPERFAMILY SSF52402 162 292 2.6E-11 T 22-04-2016 HRM2_RS00395 8fc8614f10ef05dd0eb4a6df3b916f60 392 SUPERFAMILY SSF52218 243 388 1.64E-27 T 22-04-2016 IPR029039 Flavoprotein-like domain HRM2_RS00395 8fc8614f10ef05dd0eb4a6df3b916f60 392 SMART SM00849 34 220 4.3E-36 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS00395 8fc8614f10ef05dd0eb4a6df3b916f60 392 SUPERFAMILY SSF56281 3 275 7.99E-50 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS00395 8fc8614f10ef05dd0eb4a6df3b916f60 392 PANTHER PTHR32145 1 388 1.3E-179 T 22-04-2016 HRM2_RS00395 8fc8614f10ef05dd0eb4a6df3b916f60 392 Gene3D G3DSA:3.60.15.10 1 238 1.8E-85 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS00395 8fc8614f10ef05dd0eb4a6df3b916f60 392 Gene3D G3DSA:3.40.50.360 246 385 1.7E-29 T 22-04-2016 IPR029039 Flavoprotein-like domain HRM2_RS00395 8fc8614f10ef05dd0eb4a6df3b916f60 392 Pfam PF00753 Metallo-beta-lactamase superfamily 34 167 9.6E-14 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS00395 8fc8614f10ef05dd0eb4a6df3b916f60 392 PANTHER PTHR32145:SF17 1 388 1.3E-179 T 22-04-2016 HRM2_RS00395 8fc8614f10ef05dd0eb4a6df3b916f60 392 PIRSF PIRSF005243 1 391 3.2E-126 T 22-04-2016 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 HRM2_RS00015 176f597af54b7270e85ec9cdfcaf46cc 432 Gene3D G3DSA:1.25.40.10 304 416 1.1E-8 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS00015 176f597af54b7270e85ec9cdfcaf46cc 432 SUPERFAMILY SSF48452 79 278 2.78E-14 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS00015 176f597af54b7270e85ec9cdfcaf46cc 432 PANTHER PTHR23083 37 418 2.1E-16 T 22-04-2016 HRM2_RS00015 176f597af54b7270e85ec9cdfcaf46cc 432 SUPERFAMILY SSF48452 295 420 7.32E-9 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS00015 176f597af54b7270e85ec9cdfcaf46cc 432 Gene3D G3DSA:1.25.40.10 44 303 3.3E-18 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS00015 176f597af54b7270e85ec9cdfcaf46cc 432 Pfam PF13432 Tetratricopeptide repeat 361 416 0.0027 T 22-04-2016 HRM2_RS07710 8dbbe7c0b3bf883554c89eb379123344 166 PANTHER PTHR33937:SF2 1 137 3.9E-26 T 22-04-2016 HRM2_RS07710 8dbbe7c0b3bf883554c89eb379123344 166 Gene3D G3DSA:3.30.420.130 1 114 2.5E-26 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS07710 8dbbe7c0b3bf883554c89eb379123344 166 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 14 105 7.8E-20 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS07710 8dbbe7c0b3bf883554c89eb379123344 166 SUPERFAMILY SSF53146 1 114 7.98E-25 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis HRM2_RS07710 8dbbe7c0b3bf883554c89eb379123344 166 PANTHER PTHR33937 1 137 3.9E-26 T 22-04-2016 HRM2_RS12455 b4942dae22264d9d6c950e3c5d686448 436 PANTHER PTHR30482:SF10 68 170 1.6E-70 T 22-04-2016 HRM2_RS12455 b4942dae22264d9d6c950e3c5d686448 436 PANTHER PTHR30482:SF10 187 436 1.6E-70 T 22-04-2016 HRM2_RS12455 b4942dae22264d9d6c950e3c5d686448 436 PANTHER PTHR30482 68 170 1.6E-70 T 22-04-2016 HRM2_RS12455 b4942dae22264d9d6c950e3c5d686448 436 PANTHER PTHR30482 187 436 1.6E-70 T 22-04-2016 HRM2_RS12455 b4942dae22264d9d6c950e3c5d686448 436 Pfam PF02653 Branched-chain amino acid transport system / permease component 128 393 5.0E-27 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 HRM2_RS06980 89f8ec9eb4e956add60750a31ab2f784 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 214 1.8E-22 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS06980 89f8ec9eb4e956add60750a31ab2f784 223 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 109 7.9E-30 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HRM2_RS06980 89f8ec9eb4e956add60750a31ab2f784 223 Gene3D G3DSA:1.10.3720.10 13 214 4.6E-48 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS06980 89f8ec9eb4e956add60750a31ab2f784 223 PANTHER PTHR30614 1 220 3.3E-78 T 22-04-2016 HRM2_RS06980 89f8ec9eb4e956add60750a31ab2f784 223 SUPERFAMILY SSF161098 14 200 1.02E-45 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS08810 b9b77fa6033e0eefa496e901d56bbb05 339 Gene3D G3DSA:1.20.970.10 4 67 5.8E-17 T 22-04-2016 HRM2_RS08810 b9b77fa6033e0eefa496e901d56bbb05 339 Pfam PF00591 Glycosyl transferase family, a/b domain 74 324 6.8E-92 T 22-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 HRM2_RS08810 b9b77fa6033e0eefa496e901d56bbb05 339 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 5 334 36.972 T 22-04-2016 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18|UniPathway: UPA00035 HRM2_RS08810 b9b77fa6033e0eefa496e901d56bbb05 339 SUPERFAMILY SSF52418 75 337 4.19E-95 T 22-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 HRM2_RS08810 b9b77fa6033e0eefa496e901d56bbb05 339 PANTHER PTHR11922 73 338 3.3E-113 T 22-04-2016 HRM2_RS08810 b9b77fa6033e0eefa496e901d56bbb05 339 PANTHER PTHR11922:SF5 73 338 3.3E-113 T 22-04-2016 HRM2_RS08810 b9b77fa6033e0eefa496e901d56bbb05 339 SUPERFAMILY SSF47648 1 69 1.01E-14 T 22-04-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain HRM2_RS08810 b9b77fa6033e0eefa496e901d56bbb05 339 Pfam PF02885 Glycosyl transferase family, helical bundle domain 7 66 2.6E-15 T 22-04-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain HRM2_RS08810 b9b77fa6033e0eefa496e901d56bbb05 339 Gene3D G3DSA:3.40.1030.10 73 336 2.2E-106 T 22-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 HRM2_RS08810 b9b77fa6033e0eefa496e901d56bbb05 339 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 7 333 6.8E-122 T 22-04-2016 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18|UniPathway: UPA00035 HRM2_RS12755 b87afec5a3a673bc0b2eb4862fb8b975 235 PANTHER PTHR23291:SF42 1 234 1.3E-78 T 22-04-2016 HRM2_RS12755 b87afec5a3a673bc0b2eb4862fb8b975 235 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 17 230 1.2E-61 T 22-04-2016 HRM2_RS12755 b87afec5a3a673bc0b2eb4862fb8b975 235 PANTHER PTHR23291 1 234 1.3E-78 T 22-04-2016 IPR006214 Bax inhibitor 1-related HRM2_RS18535 5c8456f14d25df80f3566e242b6c1023 269 SUPERFAMILY SSF52518 10 221 1.2E-69 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS18535 5c8456f14d25df80f3566e242b6c1023 269 PANTHER PTHR18968:SF89 4 263 1.7E-107 T 22-04-2016 HRM2_RS18535 5c8456f14d25df80f3566e242b6c1023 269 PANTHER PTHR18968 4 263 1.7E-107 T 22-04-2016 HRM2_RS18535 5c8456f14d25df80f3566e242b6c1023 269 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 49 196 1.9E-32 T 22-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HRM2_RS18535 5c8456f14d25df80f3566e242b6c1023 269 Gene3D G3DSA:3.40.50.970 13 217 1.5E-72 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS16120 5e03c4e308c84096c02d5a6b4cec1fe6 148 SUPERFAMILY SSF49764 24 147 3.14E-29 T 22-04-2016 IPR008978 HSP20-like chaperone HRM2_RS16120 5e03c4e308c84096c02d5a6b4cec1fe6 148 PANTHER PTHR11527 1 147 2.0E-25 T 22-04-2016 IPR031107 Small heat shock protein HSP20 HRM2_RS16120 5e03c4e308c84096c02d5a6b4cec1fe6 148 Pfam PF00011 Hsp20/alpha crystallin family 53 147 1.1E-17 T 22-04-2016 IPR002068 Alpha crystallin/Hsp20 domain HRM2_RS16120 5e03c4e308c84096c02d5a6b4cec1fe6 148 PANTHER PTHR11527:SF122 1 147 2.0E-25 T 22-04-2016 HRM2_RS16120 5e03c4e308c84096c02d5a6b4cec1fe6 148 Gene3D G3DSA:2.60.40.790 10 147 1.5E-27 T 22-04-2016 IPR008978 HSP20-like chaperone HRM2_RS01140 6322ce61cd3fb38cfbaafd2c74c41421 407 Pfam PF13439 Glycosyltransferase Family 4 86 198 5.0E-12 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain HRM2_RS01140 6322ce61cd3fb38cfbaafd2c74c41421 407 Pfam PF13692 Glycosyl transferases group 1 214 329 3.5E-19 T 22-04-2016 HRM2_RS01140 6322ce61cd3fb38cfbaafd2c74c41421 407 SUPERFAMILY SSF53756 1 405 1.67E-51 T 22-04-2016 HRM2_RS01140 6322ce61cd3fb38cfbaafd2c74c41421 407 Gene3D G3DSA:3.40.50.2000 215 331 5.5E-19 T 22-04-2016 HRM2_RS01140 6322ce61cd3fb38cfbaafd2c74c41421 407 PANTHER PTHR12526 110 325 3.5E-34 T 22-04-2016 HRM2_RS01140 6322ce61cd3fb38cfbaafd2c74c41421 407 PANTHER PTHR12526 1 93 3.5E-34 T 22-04-2016 HRM2_RS05000 88fe68393591942441c1dc6e5283951e 87 Gene3D G3DSA:3.40.30.10 3 63 5.6E-11 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS05000 88fe68393591942441c1dc6e5283951e 87 Pfam PF00462 Glutaredoxin 3 47 1.0E-8 T 22-04-2016 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 HRM2_RS05000 88fe68393591942441c1dc6e5283951e 87 ProSitePatterns PS00195 Glutaredoxin active site. 4 20 - T 22-04-2016 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 HRM2_RS05000 88fe68393591942441c1dc6e5283951e 87 SUPERFAMILY SSF52833 2 80 5.77E-11 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS08700 081bb0b5500913f2bb58a4f524c43802 114 Gene3D G3DSA:3.40.1260.10 1 114 1.6E-38 T 22-04-2016 IPR027396 DsrEFH-like HRM2_RS08700 081bb0b5500913f2bb58a4f524c43802 114 Pfam PF02635 DsrE/DsrF-like family 24 113 2.9E-6 T 22-04-2016 IPR003787 Sulphur relay, DsrE/F-like protein HRM2_RS08700 081bb0b5500913f2bb58a4f524c43802 114 SUPERFAMILY SSF75169 6 96 3.53E-10 T 22-04-2016 IPR027396 DsrEFH-like HRM2_RS05375 08636aa894dec141074d57cf86251d1b 283 SUPERFAMILY SSF51556 1 280 7.06E-48 T 22-04-2016 IPR032466 Metal-dependent hydrolase HRM2_RS05375 08636aa894dec141074d57cf86251d1b 283 PANTHER PTHR21240 1 280 5.5E-26 T 22-04-2016 HRM2_RS05375 08636aa894dec141074d57cf86251d1b 283 Pfam PF04909 Amidohydrolase 3 280 5.3E-31 T 22-04-2016 IPR006680 Amidohydrolase-related GO:0016787 HRM2_RS05375 08636aa894dec141074d57cf86251d1b 283 Gene3D G3DSA:3.20.20.140 1 281 2.8E-58 T 22-04-2016 HRM2_RS13175 b4e83b375a0972846f3562f4365c849a 244 PANTHER PTHR12277 9 219 2.8E-16 T 22-04-2016 HRM2_RS13175 b4e83b375a0972846f3562f4365c849a 244 Gene3D G3DSA:3.40.50.1820 2 241 5.6E-38 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS13175 b4e83b375a0972846f3562f4365c849a 244 SUPERFAMILY SSF53474 3 242 3.13E-40 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS13175 b4e83b375a0972846f3562f4365c849a 244 Pfam PF00326 Prolyl oligopeptidase family 52 242 2.6E-13 T 22-04-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 HRM2_RS17900 bb74679c23a53c0f9b43064c8db6893e 207 SUPERFAMILY SSF50447 1 207 7.42E-71 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain HRM2_RS17900 bb74679c23a53c0f9b43064c8db6893e 207 ProSitePatterns PS00474 Ribosomal protein L3 signature. 102 125 - T 22-04-2016 IPR019926 Ribosomal protein L3, conserved site HRM2_RS17900 bb74679c23a53c0f9b43064c8db6893e 207 PANTHER PTHR11229 4 207 9.3E-91 T 22-04-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17900 bb74679c23a53c0f9b43064c8db6893e 207 Gene3D G3DSA:4.10.960.10 80 157 1.1E-28 T 22-04-2016 HRM2_RS17900 bb74679c23a53c0f9b43064c8db6893e 207 Pfam PF00297 Ribosomal protein L3 95 182 1.9E-13 T 22-04-2016 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17900 bb74679c23a53c0f9b43064c8db6893e 207 Gene3D G3DSA:2.40.30.10 4 33 4.9E-10 T 22-04-2016 HRM2_RS17900 bb74679c23a53c0f9b43064c8db6893e 207 Gene3D G3DSA:2.40.30.10 158 207 4.9E-10 T 22-04-2016 HRM2_RS17900 bb74679c23a53c0f9b43064c8db6893e 207 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 204 1.6E-81 T 22-04-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17900 bb74679c23a53c0f9b43064c8db6893e 207 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 207 36.6 T 22-04-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS05570 db055b6f784caa62e8e8845cb299ff5a 345 Gene3D G3DSA:1.25.40.10 80 206 2.2E-9 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS05570 db055b6f784caa62e8e8845cb299ff5a 345 Pfam PF13525 Outer membrane lipoprotein 83 166 9.0E-8 T 22-04-2016 HRM2_RS05570 db055b6f784caa62e8e8845cb299ff5a 345 SUPERFAMILY SSF48452 80 188 1.16E-11 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS14400 ee3a56641529c10513d47f23a703a210 401 Gene3D G3DSA:3.40.640.10 55 250 1.0E-47 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS14400 ee3a56641529c10513d47f23a703a210 401 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 9 399 2.4E-128 T 22-04-2016 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 HRM2_RS14400 ee3a56641529c10513d47f23a703a210 401 Pfam PF00155 Aminotransferase class I and II 42 394 2.7E-30 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HRM2_RS14400 ee3a56641529c10513d47f23a703a210 401 PANTHER PTHR11751:SF422 8 395 7.5E-125 T 22-04-2016 HRM2_RS14400 ee3a56641529c10513d47f23a703a210 401 PANTHER PTHR11751 8 395 7.5E-125 T 22-04-2016 HRM2_RS14400 ee3a56641529c10513d47f23a703a210 401 SUPERFAMILY SSF53383 8 398 7.29E-87 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS14400 ee3a56641529c10513d47f23a703a210 401 Gene3D G3DSA:3.90.1150.10 251 396 6.1E-45 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS10085 6ec1196e5726a95f04cc6e4409e4e3f2 250 SUPERFAMILY SSF53850 1 247 2.54E-56 T 22-04-2016 HRM2_RS10085 6ec1196e5726a95f04cc6e4409e4e3f2 250 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 25 247 3.4E-53 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS10085 6ec1196e5726a95f04cc6e4409e4e3f2 250 PANTHER PTHR18966:SF191 24 246 1.5E-38 T 22-04-2016 HRM2_RS10085 6ec1196e5726a95f04cc6e4409e4e3f2 250 PANTHER PTHR18966 24 246 1.5E-38 T 22-04-2016 HRM2_RS10085 6ec1196e5726a95f04cc6e4409e4e3f2 250 Gene3D G3DSA:3.40.190.10 23 101 5.2E-41 T 22-04-2016 HRM2_RS10085 6ec1196e5726a95f04cc6e4409e4e3f2 250 Gene3D G3DSA:3.40.190.10 210 247 5.2E-41 T 22-04-2016 HRM2_RS10085 6ec1196e5726a95f04cc6e4409e4e3f2 250 Gene3D G3DSA:3.40.190.10 102 196 1.8E-14 T 22-04-2016 HRM2_RS10085 6ec1196e5726a95f04cc6e4409e4e3f2 250 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 47 60 - T 22-04-2016 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 HRM2_RS10085 6ec1196e5726a95f04cc6e4409e4e3f2 250 SMART SM00062 24 249 5.3E-54 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS03045 7f65ff7f674c119584783138d37ef750 278 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 16 132 26.209 T 22-04-2016 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|UniPathway: UPA00331 HRM2_RS03045 7f65ff7f674c119584783138d37ef750 278 PANTHER PTHR33866:SF2 9 131 1.7E-41 T 22-04-2016 HRM2_RS03045 7f65ff7f674c119584783138d37ef750 278 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 19 123 3.7E-35 T 22-04-2016 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|UniPathway: UPA00331 HRM2_RS03045 7f65ff7f674c119584783138d37ef750 278 Gene3D G3DSA:3.60.90.10 9 132 5.9E-39 T 22-04-2016 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|UniPathway: UPA00331 HRM2_RS03045 7f65ff7f674c119584783138d37ef750 278 Gene3D G3DSA:3.60.90.10 153 277 9.0E-10 T 22-04-2016 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|UniPathway: UPA00331 HRM2_RS03045 7f65ff7f674c119584783138d37ef750 278 PANTHER PTHR33866 9 131 1.7E-41 T 22-04-2016 HRM2_RS03045 7f65ff7f674c119584783138d37ef750 278 SUPERFAMILY SSF56276 19 122 1.08E-32 T 22-04-2016 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|UniPathway: UPA00331 HRM2_RS03045 7f65ff7f674c119584783138d37ef750 278 Pfam PF02675 S-adenosylmethionine decarboxylase 170 277 1.2E-8 T 22-04-2016 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|UniPathway: UPA00331 HRM2_RS03045 7f65ff7f674c119584783138d37ef750 278 Pfam PF02675 S-adenosylmethionine decarboxylase 23 124 5.0E-33 T 22-04-2016 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|UniPathway: UPA00331 HRM2_RS14075 707cfd45ecce34b9e81723a51d375664 168 PANTHER PTHR22936 25 166 2.6E-37 T 22-04-2016 IPR002610 Peptidase S54, rhomboid GO:0004252|GO:0006508|GO:0016021 HRM2_RS14075 707cfd45ecce34b9e81723a51d375664 168 SUPERFAMILY SSF144091 2 165 4.71E-26 T 22-04-2016 HRM2_RS14075 707cfd45ecce34b9e81723a51d375664 168 Pfam PF01694 Rhomboid family 37 165 7.6E-21 T 22-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 HRM2_RS14075 707cfd45ecce34b9e81723a51d375664 168 PANTHER PTHR22936:SF11 25 166 2.6E-37 T 22-04-2016 HRM2_RS14075 707cfd45ecce34b9e81723a51d375664 168 Gene3D G3DSA:1.20.1540.10 8 165 1.4E-14 T 22-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 HRM2_RS02910 59628c6acb5eb7a11ccef8944350d2fc 305 PANTHER PTHR22911 5 303 1.7E-52 T 22-04-2016 HRM2_RS02910 59628c6acb5eb7a11ccef8944350d2fc 305 Pfam PF00892 EamA-like transporter family 5 140 5.7E-17 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS02910 59628c6acb5eb7a11ccef8944350d2fc 305 Pfam PF00892 EamA-like transporter family 161 303 3.1E-12 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS02910 59628c6acb5eb7a11ccef8944350d2fc 305 PANTHER PTHR22911:SF64 5 303 1.7E-52 T 22-04-2016 HRM2_RS02910 59628c6acb5eb7a11ccef8944350d2fc 305 SUPERFAMILY SSF103481 42 143 2.35E-11 T 22-04-2016 HRM2_RS02910 59628c6acb5eb7a11ccef8944350d2fc 305 SUPERFAMILY SSF103481 200 303 4.84E-10 T 22-04-2016 HRM2_RS07005 b5089961d87f4110e7546d6fa5a1db95 450 PANTHER PTHR32479:SF9 76 275 1.8E-24 T 22-04-2016 HRM2_RS07005 b5089961d87f4110e7546d6fa5a1db95 450 PANTHER PTHR32479:SF9 349 450 1.8E-24 T 22-04-2016 HRM2_RS07005 b5089961d87f4110e7546d6fa5a1db95 450 PANTHER PTHR32479:SF9 292 325 1.8E-24 T 22-04-2016 HRM2_RS07005 b5089961d87f4110e7546d6fa5a1db95 450 PANTHER PTHR32479 76 275 1.8E-24 T 22-04-2016 HRM2_RS07005 b5089961d87f4110e7546d6fa5a1db95 450 PANTHER PTHR32479 349 450 1.8E-24 T 22-04-2016 HRM2_RS07005 b5089961d87f4110e7546d6fa5a1db95 450 PANTHER PTHR32479 292 325 1.8E-24 T 22-04-2016 HRM2_RS07005 b5089961d87f4110e7546d6fa5a1db95 450 Pfam PF02754 Cysteine-rich domain 173 256 2.6E-10 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS07005 b5089961d87f4110e7546d6fa5a1db95 450 Pfam PF02754 Cysteine-rich domain 351 435 1.8E-7 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS15575 7aa16c252dee1ca14d528dbfbc3f35d6 233 SUPERFAMILY SSF110997 155 229 2.22E-13 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 HRM2_RS15575 7aa16c252dee1ca14d528dbfbc3f35d6 233 Pfam PF05036 Sporulation related domain 156 229 8.6E-12 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 HRM2_RS15575 7aa16c252dee1ca14d528dbfbc3f35d6 233 Gene3D G3DSA:3.30.70.1070 154 229 1.1E-13 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 HRM2_RS16190 324c09841a3b9ac8247753712c85300a 501 SUPERFAMILY SSF56801 12 500 1.31E-120 T 22-04-2016 HRM2_RS16190 324c09841a3b9ac8247753712c85300a 501 Gene3D G3DSA:3.40.50.980 173 327 6.0E-29 T 22-04-2016 HRM2_RS16190 324c09841a3b9ac8247753712c85300a 501 PANTHER PTHR24096 13 495 3.2E-121 T 22-04-2016 HRM2_RS16190 324c09841a3b9ac8247753712c85300a 501 Gene3D G3DSA:3.40.50.980 13 172 1.0E-26 T 22-04-2016 HRM2_RS16190 324c09841a3b9ac8247753712c85300a 501 Gene3D G3DSA:3.30.300.30 403 500 1.4E-30 T 22-04-2016 HRM2_RS16190 324c09841a3b9ac8247753712c85300a 501 Pfam PF13193 AMP-binding enzyme C-terminal domain 417 491 4.8E-18 T 22-04-2016 IPR025110 AMP-binding enzyme C-terminal domain HRM2_RS16190 324c09841a3b9ac8247753712c85300a 501 Pfam PF00501 AMP-binding enzyme 17 400 5.7E-73 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS16190 324c09841a3b9ac8247753712c85300a 501 Gene3D G3DSA:2.30.38.10 333 400 1.3E-18 T 22-04-2016 HRM2_RS21255 aafee71b229ed018a6d9ec7495171f4a 387 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 41 385 4.7E-38 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 HRM2_RS21255 aafee71b229ed018a6d9ec7495171f4a 387 Gene3D G3DSA:2.40.50.100 202 233 4.6E-12 T 22-04-2016 HRM2_RS21255 aafee71b229ed018a6d9ec7495171f4a 387 Gene3D G3DSA:2.40.50.100 67 99 4.6E-12 T 22-04-2016 HRM2_RS21255 aafee71b229ed018a6d9ec7495171f4a 387 PANTHER PTHR30469 4 386 6.8E-44 T 22-04-2016 HRM2_RS21255 aafee71b229ed018a6d9ec7495171f4a 387 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 65 266 5.7E-12 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain HRM2_RS21255 aafee71b229ed018a6d9ec7495171f4a 387 SUPERFAMILY SSF111369 56 259 1.57E-15 T 22-04-2016 HRM2_RS20245 aa0e030053a178559c513b719aba697c 409 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 21 408 2.4E-177 T 22-04-2016 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 HRM2_RS20245 aa0e030053a178559c513b719aba697c 409 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 26 404 1.9E-106 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 HRM2_RS20245 aa0e030053a178559c513b719aba697c 409 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 295 314 - T 22-04-2016 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 HRM2_RS20245 aa0e030053a178559c513b719aba697c 409 SMART SM01329 25 404 6.6E-166 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 HRM2_RS20245 aa0e030053a178559c513b719aba697c 409 PANTHER PTHR11835:SF52 22 159 1.6E-203 T 22-04-2016 HRM2_RS20245 aa0e030053a178559c513b719aba697c 409 PANTHER PTHR11835:SF52 179 246 1.6E-203 T 22-04-2016 HRM2_RS20245 aa0e030053a178559c513b719aba697c 409 PANTHER PTHR11835:SF52 267 408 1.6E-203 T 22-04-2016 HRM2_RS20245 aa0e030053a178559c513b719aba697c 409 PANTHER PTHR11835 22 159 1.6E-203 T 22-04-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 HRM2_RS20245 aa0e030053a178559c513b719aba697c 409 PANTHER PTHR11835 179 246 1.6E-203 T 22-04-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 HRM2_RS20245 aa0e030053a178559c513b719aba697c 409 PANTHER PTHR11835 267 408 1.6E-203 T 22-04-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 HRM2_RS20245 aa0e030053a178559c513b719aba697c 409 Gene3D G3DSA:3.40.718.10 22 408 1.1E-142 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 HRM2_RS20245 aa0e030053a178559c513b719aba697c 409 SUPERFAMILY SSF53659 21 408 5.57E-129 T 22-04-2016 HRM2_RS21090 278b20d01edacb19214a8c024c360af0 350 PANTHER PTHR18968 15 299 8.5E-130 T 22-04-2016 HRM2_RS21090 278b20d01edacb19214a8c024c360af0 350 PANTHER PTHR18968:SF122 15 299 8.5E-130 T 22-04-2016 HRM2_RS21090 278b20d01edacb19214a8c024c360af0 350 SUPERFAMILY SSF52518 16 239 6.12E-65 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS21090 278b20d01edacb19214a8c024c360af0 350 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 65 213 9.1E-28 T 22-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HRM2_RS21090 278b20d01edacb19214a8c024c360af0 350 Gene3D G3DSA:3.40.50.970 27 241 1.7E-62 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS14745 6c15206a52777900bdcbd56e82bcfcee 418 Gene3D G3DSA:3.40.50.2000 206 373 3.0E-25 T 22-04-2016 HRM2_RS14745 6c15206a52777900bdcbd56e82bcfcee 418 Pfam PF00534 Glycosyl transferases group 1 224 383 5.4E-21 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 HRM2_RS14745 6c15206a52777900bdcbd56e82bcfcee 418 Pfam PF13439 Glycosyltransferase Family 4 14 214 4.3E-10 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain HRM2_RS14745 6c15206a52777900bdcbd56e82bcfcee 418 PANTHER PTHR12526 170 416 8.1E-46 T 22-04-2016 HRM2_RS14745 6c15206a52777900bdcbd56e82bcfcee 418 PANTHER PTHR12526 1 149 8.1E-46 T 22-04-2016 HRM2_RS14745 6c15206a52777900bdcbd56e82bcfcee 418 SUPERFAMILY SSF53756 12 408 3.45E-56 T 22-04-2016 HRM2_RS00525 cd25343a7882c7fcbf9915f76a6b9e7a 122 PANTHER PTHR10584:SF191 1 67 2.0E-18 T 22-04-2016 HRM2_RS00525 cd25343a7882c7fcbf9915f76a6b9e7a 122 Pfam PF04241 Protein of unknown function (DUF423) 19 105 6.5E-31 T 22-04-2016 IPR006696 Protein of unknown function DUF423 HRM2_RS00525 cd25343a7882c7fcbf9915f76a6b9e7a 122 PANTHER PTHR10584 1 67 2.0E-18 T 22-04-2016 HRM2_RS22410 640270320591c82d4258686007b4102b 366 PANTHER PTHR24220 6 312 4.3E-124 T 22-04-2016 HRM2_RS22410 640270320591c82d4258686007b4102b 366 SUPERFAMILY SSF52540 5 241 1.5E-80 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22410 640270320591c82d4258686007b4102b 366 Pfam PF08402 TOBE domain 281 359 1.0E-6 T 22-04-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 HRM2_RS22410 640270320591c82d4258686007b4102b 366 Gene3D G3DSA:3.40.50.300 2 236 1.4E-76 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22410 640270320591c82d4258686007b4102b 366 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS22410 640270320591c82d4258686007b4102b 366 SUPERFAMILY SSF50331 237 358 1.81E-10 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal HRM2_RS22410 640270320591c82d4258686007b4102b 366 SMART SM00382 29 212 1.1E-16 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS22410 640270320591c82d4258686007b4102b 366 PANTHER PTHR24220:SF150 6 312 4.3E-124 T 22-04-2016 HRM2_RS22410 640270320591c82d4258686007b4102b 366 Pfam PF00005 ABC transporter 21 162 1.5E-35 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS14165 8499f288b6a62a6e90dc5c349c555197 384 Pfam PF00817 impB/mucB/samB family 6 151 1.0E-49 T 22-04-2016 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS14165 8499f288b6a62a6e90dc5c349c555197 384 SUPERFAMILY SSF56672 2 229 2.4E-79 T 22-04-2016 HRM2_RS14165 8499f288b6a62a6e90dc5c349c555197 384 Gene3D G3DSA:3.30.70.270 63 160 3.8E-31 T 22-04-2016 HRM2_RS14165 8499f288b6a62a6e90dc5c349c555197 384 Pfam PF11799 impB/mucB/samB family C-terminal domain 236 340 4.2E-17 T 22-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS14165 8499f288b6a62a6e90dc5c349c555197 384 SUPERFAMILY SSF100879 236 334 7.06E-25 T 22-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS14165 8499f288b6a62a6e90dc5c349c555197 384 Gene3D G3DSA:3.30.1490.100 238 340 4.0E-27 T 22-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS14165 8499f288b6a62a6e90dc5c349c555197 384 PANTHER PTHR11076 1 357 3.4E-118 T 22-04-2016 HRM2_RS14165 8499f288b6a62a6e90dc5c349c555197 384 Hamap MF_01113 DNA polymerase IV [dinB]. 1 347 33.094 T 22-04-2016 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS14165 8499f288b6a62a6e90dc5c349c555197 384 Gene3D G3DSA:1.10.150.20 164 229 3.8E-16 T 22-04-2016 HRM2_RS17585 a3d28b319f3bc760e5fd421368d1bfdd 201 Gene3D G3DSA:3.40.50.300 7 191 9.8E-20 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17585 a3d28b319f3bc760e5fd421368d1bfdd 201 Pfam PF00071 Ras family 14 189 7.5E-8 T 22-04-2016 IPR001806 Small GTPase superfamily GO:0005525|GO:0007264 HRM2_RS17585 a3d28b319f3bc760e5fd421368d1bfdd 201 SUPERFAMILY SSF52540 13 189 2.56E-21 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17585 a3d28b319f3bc760e5fd421368d1bfdd 201 PANTHER PTHR11711 3 198 8.7E-32 T 22-04-2016 HRM2_RS17585 a3d28b319f3bc760e5fd421368d1bfdd 201 PANTHER PTHR11711:SF128 3 198 8.7E-32 T 22-04-2016 HRM2_RS23945 5198a6f45f8ce26b4d964849b8c24ab2 346 Gene3D G3DSA:1.50.10.20 19 144 2.0E-8 T 22-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid HRM2_RS23945 5198a6f45f8ce26b4d964849b8c24ab2 346 SUPERFAMILY SSF48208 23 331 5.21E-30 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 HRM2_RS19865 2911deff4aeda0a5eaa3fc9d61b133ae 494 Pfam PF00939 Sodium:sulfate symporter transmembrane region 50 488 3.2E-40 T 22-04-2016 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 HRM2_RS19865 2911deff4aeda0a5eaa3fc9d61b133ae 494 PANTHER PTHR10283 7 487 1.9E-70 T 22-04-2016 HRM2_RS19865 2911deff4aeda0a5eaa3fc9d61b133ae 494 PANTHER PTHR10283:SF82 7 487 1.9E-70 T 22-04-2016 HRM2_RS15645 a6c4ba136f1bee1b59fd8537eedf42d1 201 Pfam PF12654 Domain of unknown function (DUF3786) 21 192 4.1E-33 T 22-04-2016 IPR024264 Domain of unknown function DUF3786 HRM2_RS01520 b9eeb2ab66062ac95fba20a23747bafe 302 PANTHER PTHR24322:SF482 13 32 2.2E-60 T 22-04-2016 HRM2_RS01520 b9eeb2ab66062ac95fba20a23747bafe 302 PANTHER PTHR24322:SF482 49 150 2.2E-60 T 22-04-2016 HRM2_RS01520 b9eeb2ab66062ac95fba20a23747bafe 302 PANTHER PTHR24322:SF482 166 198 2.2E-60 T 22-04-2016 HRM2_RS01520 b9eeb2ab66062ac95fba20a23747bafe 302 PANTHER PTHR24322 13 32 2.2E-60 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS01520 b9eeb2ab66062ac95fba20a23747bafe 302 PANTHER PTHR24322 49 150 2.2E-60 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS01520 b9eeb2ab66062ac95fba20a23747bafe 302 PANTHER PTHR24322 166 198 2.2E-60 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS01520 b9eeb2ab66062ac95fba20a23747bafe 302 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 205 0.0038 T 22-04-2016 HRM2_RS01520 b9eeb2ab66062ac95fba20a23747bafe 302 SUPERFAMILY SSF51735 4 247 1.34E-60 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS01520 b9eeb2ab66062ac95fba20a23747bafe 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 7.4E-24 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS01520 b9eeb2ab66062ac95fba20a23747bafe 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 7.4E-24 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS01520 b9eeb2ab66062ac95fba20a23747bafe 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 7.4E-24 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS01520 b9eeb2ab66062ac95fba20a23747bafe 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 7.4E-24 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS01520 b9eeb2ab66062ac95fba20a23747bafe 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 7.4E-24 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS01520 b9eeb2ab66062ac95fba20a23747bafe 302 Pfam PF00106 short chain dehydrogenase 10 198 6.2E-40 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS01520 b9eeb2ab66062ac95fba20a23747bafe 302 Gene3D G3DSA:3.40.50.720 2 245 3.8E-62 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS01520 b9eeb2ab66062ac95fba20a23747bafe 302 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 8.6E-9 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS01520 b9eeb2ab66062ac95fba20a23747bafe 302 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 8.6E-9 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS01520 b9eeb2ab66062ac95fba20a23747bafe 302 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 93 104 8.6E-9 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS04810 cd8bb69a96857d65d0d628123f6a7aef 107 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 7 98 6.8E-12 T 22-04-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family HRM2_RS18360 b3cf220f687c674e8198eadc40aa7b8f 901 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 22-04-2016 IPR019776 Flagellar basal body rod protein, conserved site HRM2_RS18360 b3cf220f687c674e8198eadc40aa7b8f 901 Pfam PF07559 Flagellar basal body protein FlaE 193 298 1.3E-13 T 22-04-2016 IPR011491 Flagellar hook protein FlgE HRM2_RS18360 b3cf220f687c674e8198eadc40aa7b8f 901 Pfam PF00460 Flagella basal body rod protein 9 37 1.8E-6 T 22-04-2016 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 HRM2_RS18360 b3cf220f687c674e8198eadc40aa7b8f 901 SUPERFAMILY SSF117143 84 232 4.18E-50 T 22-04-2016 HRM2_RS18360 b3cf220f687c674e8198eadc40aa7b8f 901 SUPERFAMILY SSF117143 532 570 4.18E-50 T 22-04-2016 HRM2_RS18360 b3cf220f687c674e8198eadc40aa7b8f 901 SUPERFAMILY SSF117143 765 862 4.18E-50 T 22-04-2016 HRM2_RS18360 b3cf220f687c674e8198eadc40aa7b8f 901 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 695 883 1.9E-41 T 22-04-2016 IPR020013 Fagellar hook-basal body protein, FlgE/F/G HRM2_RS18360 b3cf220f687c674e8198eadc40aa7b8f 901 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 6 297 6.1E-52 T 22-04-2016 IPR020013 Fagellar hook-basal body protein, FlgE/F/G HRM2_RS18360 b3cf220f687c674e8198eadc40aa7b8f 901 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 822 900 8.7E-23 T 22-04-2016 IPR010930 Flagellar basal-body/hook protein, C-terminal domain HRM2_RS18360 b3cf220f687c674e8198eadc40aa7b8f 901 PANTHER PTHR30435 2 130 9.0E-92 T 22-04-2016 HRM2_RS18360 b3cf220f687c674e8198eadc40aa7b8f 901 PANTHER PTHR30435 779 901 9.0E-92 T 22-04-2016 HRM2_RS18360 b3cf220f687c674e8198eadc40aa7b8f 901 PANTHER PTHR30435:SF1 2 130 9.0E-92 T 22-04-2016 HRM2_RS18360 b3cf220f687c674e8198eadc40aa7b8f 901 PANTHER PTHR30435:SF1 779 901 9.0E-92 T 22-04-2016 HRM2_RS23035 e36673cd6689beb3d0dacc39ac67afe0 246 SUPERFAMILY SSF55729 10 118 4.82E-30 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS23035 e36673cd6689beb3d0dacc39ac67afe0 246 SUPERFAMILY SSF55729 156 215 4.82E-30 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS23035 e36673cd6689beb3d0dacc39ac67afe0 246 TIGRFAM TIGR03694 exosort_acyl: N-acyl amino acid synthase, PEP-CTERM/exosortase system-associated 10 234 2.0E-58 T 22-04-2016 IPR022484 PEP-CTERM/exosortase system-associated acyltransferase, predicted HRM2_RS23035 e36673cd6689beb3d0dacc39ac67afe0 246 Pfam PF13444 Acetyltransferase (GNAT) domain 27 119 2.5E-15 T 22-04-2016 HRM2_RS23035 e36673cd6689beb3d0dacc39ac67afe0 246 Gene3D G3DSA:3.40.630.30 154 213 1.7E-39 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS23035 e36673cd6689beb3d0dacc39ac67afe0 246 Gene3D G3DSA:3.40.630.30 15 120 1.7E-39 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS12380 852ca7bf874fcc8d3227ced1ea905d43 162 Pfam PF01252 Signal peptidase (SPase) II 14 156 5.0E-36 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 HRM2_RS12380 852ca7bf874fcc8d3227ced1ea905d43 162 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 51 59 1.0E-14 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 HRM2_RS12380 852ca7bf874fcc8d3227ced1ea905d43 162 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 100 115 1.0E-14 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 HRM2_RS12380 852ca7bf874fcc8d3227ced1ea905d43 162 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 136 152 1.0E-14 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 HRM2_RS12380 852ca7bf874fcc8d3227ced1ea905d43 162 ProSitePatterns PS00855 Signal peptidases II signature. 103 115 - T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 HRM2_RS12380 852ca7bf874fcc8d3227ced1ea905d43 162 PANTHER PTHR33695 4 161 3.7E-47 T 22-04-2016 HRM2_RS12380 852ca7bf874fcc8d3227ced1ea905d43 162 PANTHER PTHR33695:SF1 4 161 3.7E-47 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 HRM2_RS12380 852ca7bf874fcc8d3227ced1ea905d43 162 TIGRFAM TIGR00077 lspA: signal peptidase II 7 158 1.3E-36 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 HRM2_RS12380 852ca7bf874fcc8d3227ced1ea905d43 162 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 4 161 17.421 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 HRM2_RS15360 92fc186004412b0dc4ed9dddeb70f12c 565 SUPERFAMILY SSF56112 204 441 2.64E-30 T 22-04-2016 IPR011009 Protein kinase-like domain HRM2_RS15360 92fc186004412b0dc4ed9dddeb70f12c 565 SUPERFAMILY SSF56112 106 169 2.64E-30 T 22-04-2016 IPR011009 Protein kinase-like domain HRM2_RS15360 92fc186004412b0dc4ed9dddeb70f12c 565 PANTHER PTHR10566 12 564 3.1E-143 T 22-04-2016 HRM2_RS15360 92fc186004412b0dc4ed9dddeb70f12c 565 PANTHER PTHR10566:SF10 12 564 3.1E-143 T 22-04-2016 HRM2_RS15360 92fc186004412b0dc4ed9dddeb70f12c 565 Gene3D G3DSA:3.90.1200.10 254 326 2.5E-10 T 22-04-2016 HRM2_RS15360 92fc186004412b0dc4ed9dddeb70f12c 565 Pfam PF03109 ABC1 family 124 241 3.1E-33 T 22-04-2016 IPR004147 UbiB domain HRM2_RS13855 5c0c70d4b649085e35acbd6056708eaa 359 PANTHER PTHR11228:SF32 17 356 4.4E-105 T 22-04-2016 HRM2_RS13855 5c0c70d4b649085e35acbd6056708eaa 359 PANTHER PTHR11228 17 356 4.4E-105 T 22-04-2016 HRM2_RS13855 5c0c70d4b649085e35acbd6056708eaa 359 Pfam PF04055 Radical SAM superfamily 22 172 5.2E-18 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS13855 5c0c70d4b649085e35acbd6056708eaa 359 SUPERFAMILY SSF102114 10 333 2.22E-72 T 22-04-2016 HRM2_RS13855 5c0c70d4b649085e35acbd6056708eaa 359 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 266 352 1.4E-9 T 22-04-2016 IPR023885 4Fe4S-binding SPASM domain HRM2_RS13855 5c0c70d4b649085e35acbd6056708eaa 359 Gene3D G3DSA:3.20.20.70 8 343 2.6E-80 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS13855 5c0c70d4b649085e35acbd6056708eaa 359 Pfam PF13353 4Fe-4S single cluster domain 17 131 2.6E-7 T 22-04-2016 HRM2_RS13855 5c0c70d4b649085e35acbd6056708eaa 359 TIGRFAM TIGR04545 rSAM_ahbD_hemeb: heme b synthase 18 356 3.0E-168 T 22-04-2016 IPR030896 Heme b synthase HRM2_RS13855 5c0c70d4b649085e35acbd6056708eaa 359 PIRSF PIRSF037420 3 359 1.0E-111 T 22-04-2016 IPR017200 Coenzyme PQQ synthesis protein E UniPathway: UPA00539 HRM2_RS13855 5c0c70d4b649085e35acbd6056708eaa 359 Pfam PF13186 Iron-sulfur cluster-binding domain 266 325 9.9E-5 T 22-04-2016 IPR023885 4Fe4S-binding SPASM domain HRM2_RS00490 a8fa881e09d1960b230b113e11a2c2ce 248 SUPERFAMILY SSF161098 51 234 1.44E-30 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS00490 a8fa881e09d1960b230b113e11a2c2ce 248 Gene3D G3DSA:1.10.3720.10 50 242 9.9E-24 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS00490 a8fa881e09d1960b230b113e11a2c2ce 248 PANTHER PTHR30151 4 247 1.0E-53 T 22-04-2016 HRM2_RS00490 a8fa881e09d1960b230b113e11a2c2ce 248 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 232 1.1E-23 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS18250 95bb841c66e58706e44b39aa11ba0324 373 Pfam PF02119 Flagellar P-ring protein 31 372 1.1E-136 T 22-04-2016 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 HRM2_RS18250 95bb841c66e58706e44b39aa11ba0324 373 Hamap MF_00416 Flagellar P-ring protein [flgI]. 8 373 36.143 T 22-04-2016 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 HRM2_RS18250 95bb841c66e58706e44b39aa11ba0324 373 PANTHER PTHR30381 14 373 1.5E-140 T 22-04-2016 HRM2_RS18250 95bb841c66e58706e44b39aa11ba0324 373 PANTHER PTHR30381:SF1 14 373 1.5E-140 T 22-04-2016 HRM2_RS18250 95bb841c66e58706e44b39aa11ba0324 373 PRINTS PR01010 Flagellar P-ring protein signature 90 109 3.6E-81 T 22-04-2016 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 HRM2_RS18250 95bb841c66e58706e44b39aa11ba0324 373 PRINTS PR01010 Flagellar P-ring protein signature 46 61 3.6E-81 T 22-04-2016 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 HRM2_RS18250 95bb841c66e58706e44b39aa11ba0324 373 PRINTS PR01010 Flagellar P-ring protein signature 129 147 3.6E-81 T 22-04-2016 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 HRM2_RS18250 95bb841c66e58706e44b39aa11ba0324 373 PRINTS PR01010 Flagellar P-ring protein signature 260 272 3.6E-81 T 22-04-2016 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 HRM2_RS18250 95bb841c66e58706e44b39aa11ba0324 373 PRINTS PR01010 Flagellar P-ring protein signature 112 129 3.6E-81 T 22-04-2016 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 HRM2_RS18250 95bb841c66e58706e44b39aa11ba0324 373 PRINTS PR01010 Flagellar P-ring protein signature 65 80 3.6E-81 T 22-04-2016 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 HRM2_RS18250 95bb841c66e58706e44b39aa11ba0324 373 PRINTS PR01010 Flagellar P-ring protein signature 31 46 3.6E-81 T 22-04-2016 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 HRM2_RS18250 95bb841c66e58706e44b39aa11ba0324 373 PRINTS PR01010 Flagellar P-ring protein signature 195 213 3.6E-81 T 22-04-2016 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 HRM2_RS18250 95bb841c66e58706e44b39aa11ba0324 373 PRINTS PR01010 Flagellar P-ring protein signature 169 187 3.6E-81 T 22-04-2016 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 HRM2_RS21145 83b5a8824190af0d72268f05ca7fdc97 226 PANTHER PTHR26402:SF614 4 224 5.4E-85 T 22-04-2016 HRM2_RS21145 83b5a8824190af0d72268f05ca7fdc97 226 SMART SM00862 148 224 2.4E-20 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HRM2_RS21145 83b5a8824190af0d72268f05ca7fdc97 226 Gene3D G3DSA:3.40.50.2300 2 122 3.2E-37 T 22-04-2016 HRM2_RS21145 83b5a8824190af0d72268f05ca7fdc97 226 SUPERFAMILY SSF52172 2 123 8.68E-37 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS21145 83b5a8824190af0d72268f05ca7fdc97 226 Pfam PF00072 Response regulator receiver domain 6 115 8.3E-26 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS21145 83b5a8824190af0d72268f05ca7fdc97 226 Gene3D G3DSA:1.10.10.10 125 224 1.0E-28 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS21145 83b5a8824190af0d72268f05ca7fdc97 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 224 2.6E-20 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HRM2_RS21145 83b5a8824190af0d72268f05ca7fdc97 226 SUPERFAMILY SSF46894 125 225 1.87E-26 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HRM2_RS21145 83b5a8824190af0d72268f05ca7fdc97 226 SMART SM00448 4 114 6.5E-34 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS21145 83b5a8824190af0d72268f05ca7fdc97 226 PANTHER PTHR26402 4 224 5.4E-85 T 22-04-2016 HRM2_RS10200 79d67e9fb7d79ceb6252dd820e249c3a 401 SMART SM00974 287 381 9.1E-20 T 22-04-2016 IPR018306 Bacteriophage T5, Orf172 DNA-binding HRM2_RS10200 79d67e9fb7d79ceb6252dd820e249c3a 401 Pfam PF10544 T5orf172 domain 272 379 9.8E-13 T 22-04-2016 IPR018306 Bacteriophage T5, Orf172 DNA-binding HRM2_RS03510 e6ce1be080ac49c97f8c16236b9d86c5 229 PANTHER PTHR34300 10 220 2.5E-69 T 22-04-2016 HRM2_RS03510 e6ce1be080ac49c97f8c16236b9d86c5 229 PANTHER PTHR34300:SF2 10 220 2.5E-69 T 22-04-2016 HRM2_RS03510 e6ce1be080ac49c97f8c16236b9d86c5 229 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 25 218 1.3E-65 T 22-04-2016 IPR003744 Protein of unknown function DUF165 HRM2_RS03510 e6ce1be080ac49c97f8c16236b9d86c5 229 Pfam PF02592 Putative vitamin uptake transporter 56 216 1.4E-49 T 22-04-2016 IPR003744 Protein of unknown function DUF165 HRM2_RS25565 20bbead99c3b3b25a0c27c8f36f79e34 489 PANTHER PTHR21021:SF19 22 29 1.5E-50 T 22-04-2016 HRM2_RS25565 20bbead99c3b3b25a0c27c8f36f79e34 489 PANTHER PTHR21021:SF19 247 489 1.5E-50 T 22-04-2016 HRM2_RS25565 20bbead99c3b3b25a0c27c8f36f79e34 489 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 295 488 6.4E-44 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 HRM2_RS25565 20bbead99c3b3b25a0c27c8f36f79e34 489 SUPERFAMILY SSF81606 282 488 7.85E-7 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 HRM2_RS25565 20bbead99c3b3b25a0c27c8f36f79e34 489 PANTHER PTHR21021 22 29 1.5E-50 T 22-04-2016 HRM2_RS25565 20bbead99c3b3b25a0c27c8f36f79e34 489 PANTHER PTHR21021 247 489 1.5E-50 T 22-04-2016 HRM2_RS25565 20bbead99c3b3b25a0c27c8f36f79e34 489 SMART SM00331 269 488 1.9E-38 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 HRM2_RS04650 518e99281124cd91b1e0500f2e80e639 99 Pfam PF04012 PspA/IM30 family 3 47 4.7E-11 T 22-04-2016 IPR007157 PspA/IM30 HRM2_RS06370 12a6cda249be6fd34ed67024fc618123 166 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 46 142 3.2E-10 T 22-04-2016 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801|UniPathway: UPA00562 HRM2_RS06370 12a6cda249be6fd34ed67024fc618123 166 Gene3D G3DSA:3.90.1590.10 21 161 9.9E-22 T 22-04-2016 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801|UniPathway: UPA00562 HRM2_RS06370 12a6cda249be6fd34ed67024fc618123 166 PANTHER PTHR33337:SF1 16 166 4.8E-54 T 22-04-2016 HRM2_RS06370 12a6cda249be6fd34ed67024fc618123 166 SUPERFAMILY SSF51316 12 161 8.27E-29 T 22-04-2016 IPR011057 Mss4-like HRM2_RS06370 12a6cda249be6fd34ed67024fc618123 166 PANTHER PTHR33337 16 166 4.8E-54 T 22-04-2016 HRM2_RS18340 6f187d1e29d57d86f98086cd28c1f905 121 Pfam PF04347 Flagellar biosynthesis protein, FliO 30 108 6.3E-15 T 22-04-2016 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 HRM2_RS18340 6f187d1e29d57d86f98086cd28c1f905 121 TIGRFAM TIGR03500 FliO_TIGR: flagellar biosynthetic protein FliO 18 85 1.7E-18 T 22-04-2016 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 HRM2_RS19890 daa8dbda737fe5ab41dcc463a5eb5b07 583 SMART SM00388 348 420 6.1E-5 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS19890 daa8dbda737fe5ab41dcc463a5eb5b07 583 Pfam PF02743 Cache domain 61 283 1.2E-17 T 22-04-2016 IPR033479 Double Cache domain 1 HRM2_RS19890 daa8dbda737fe5ab41dcc463a5eb5b07 583 Gene3D G3DSA:3.30.450.20 106 189 2.8E-6 T 22-04-2016 HRM2_RS19890 daa8dbda737fe5ab41dcc463a5eb5b07 583 PANTHER PTHR24423:SF497 338 579 2.2E-63 T 22-04-2016 HRM2_RS19890 daa8dbda737fe5ab41dcc463a5eb5b07 583 PANTHER PTHR24423:SF497 33 43 2.2E-63 T 22-04-2016 HRM2_RS19890 daa8dbda737fe5ab41dcc463a5eb5b07 583 Gene3D G3DSA:3.30.450.20 190 292 5.7E-5 T 22-04-2016 HRM2_RS19890 daa8dbda737fe5ab41dcc463a5eb5b07 583 Gene3D G3DSA:1.10.287.130 346 416 2.9E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS19890 daa8dbda737fe5ab41dcc463a5eb5b07 583 SUPERFAMILY SSF55874 411 572 1.06E-40 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS19890 daa8dbda737fe5ab41dcc463a5eb5b07 583 Pfam PF00512 His Kinase A (phospho-acceptor) domain 350 417 1.4E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS19890 daa8dbda737fe5ab41dcc463a5eb5b07 583 SUPERFAMILY SSF47384 339 416 1.86E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS19890 daa8dbda737fe5ab41dcc463a5eb5b07 583 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 463 570 7.6E-25 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS19890 daa8dbda737fe5ab41dcc463a5eb5b07 583 PANTHER PTHR24423 338 579 2.2E-63 T 22-04-2016 HRM2_RS19890 daa8dbda737fe5ab41dcc463a5eb5b07 583 PANTHER PTHR24423 33 43 2.2E-63 T 22-04-2016 HRM2_RS19890 daa8dbda737fe5ab41dcc463a5eb5b07 583 PRINTS PR00344 Bacterial sensor protein C-terminal signature 500 514 1.6E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS19890 daa8dbda737fe5ab41dcc463a5eb5b07 583 PRINTS PR00344 Bacterial sensor protein C-terminal signature 531 549 1.6E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS19890 daa8dbda737fe5ab41dcc463a5eb5b07 583 PRINTS PR00344 Bacterial sensor protein C-terminal signature 555 568 1.6E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS19890 daa8dbda737fe5ab41dcc463a5eb5b07 583 PRINTS PR00344 Bacterial sensor protein C-terminal signature 518 528 1.6E-18 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS19890 daa8dbda737fe5ab41dcc463a5eb5b07 583 Gene3D G3DSA:3.30.565.10 422 570 1.1E-41 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS19890 daa8dbda737fe5ab41dcc463a5eb5b07 583 SMART SM00387 462 571 1.3E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS17470 535f47c8976da7176b4b0bda3e54306d 147 PANTHER PTHR34583:SF2 7 70 2.2E-32 T 22-04-2016 HRM2_RS17470 535f47c8976da7176b4b0bda3e54306d 147 PANTHER PTHR34583:SF2 90 139 2.2E-32 T 22-04-2016 HRM2_RS17470 535f47c8976da7176b4b0bda3e54306d 147 PANTHER PTHR34583 7 70 2.2E-32 T 22-04-2016 HRM2_RS17470 535f47c8976da7176b4b0bda3e54306d 147 PANTHER PTHR34583 90 139 2.2E-32 T 22-04-2016 HRM2_RS17470 535f47c8976da7176b4b0bda3e54306d 147 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 16 137 4.0E-23 T 22-04-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 HRM2_RS18030 4e62728719700629bd75ffdf3cb7ac1b 562 Pfam PF00072 Response regulator receiver domain 435 557 4.6E-17 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18030 4e62728719700629bd75ffdf3cb7ac1b 562 Pfam PF13646 HEAT repeats 199 255 1.9E-7 T 22-04-2016 HRM2_RS18030 4e62728719700629bd75ffdf3cb7ac1b 562 Pfam PF13646 HEAT repeats 263 333 4.1E-8 T 22-04-2016 HRM2_RS18030 4e62728719700629bd75ffdf3cb7ac1b 562 SUPERFAMILY SSF52172 432 561 2.7E-23 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS18030 4e62728719700629bd75ffdf3cb7ac1b 562 Gene3D G3DSA:3.40.50.2300 430 562 6.3E-30 T 22-04-2016 HRM2_RS18030 4e62728719700629bd75ffdf3cb7ac1b 562 SUPERFAMILY SSF48371 78 285 1.55E-23 T 22-04-2016 IPR016024 Armadillo-type fold GO:0005488 HRM2_RS18030 4e62728719700629bd75ffdf3cb7ac1b 562 SUPERFAMILY SSF48371 262 391 1.24E-5 T 22-04-2016 IPR016024 Armadillo-type fold GO:0005488 HRM2_RS18030 4e62728719700629bd75ffdf3cb7ac1b 562 PANTHER PTHR26402 433 561 4.4E-24 T 22-04-2016 HRM2_RS18030 4e62728719700629bd75ffdf3cb7ac1b 562 Gene3D G3DSA:1.25.10.10 281 377 5.9E-5 T 22-04-2016 IPR011989 Armadillo-like helical HRM2_RS18030 4e62728719700629bd75ffdf3cb7ac1b 562 Gene3D G3DSA:1.25.10.10 35 280 7.8E-24 T 22-04-2016 IPR011989 Armadillo-like helical HRM2_RS18030 4e62728719700629bd75ffdf3cb7ac1b 562 SMART SM00448 433 557 4.2E-17 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS11770 e0391c94c43cfba9b437b0e580687837 465 PANTHER PTHR31302:SF6 221 464 5.8E-47 T 22-04-2016 HRM2_RS11770 e0391c94c43cfba9b437b0e580687837 465 SUPERFAMILY SSF56300 241 463 4.22E-29 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS11770 e0391c94c43cfba9b437b0e580687837 465 Pfam PF01864 Putative integral membrane protein DUF46 10 131 2.4E-12 T 22-04-2016 IPR032690 CDP-archaeol synthase KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349|UniPathway: UPA00940 HRM2_RS11770 e0391c94c43cfba9b437b0e580687837 465 Gene3D G3DSA:3.60.21.10 241 423 2.3E-19 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS11770 e0391c94c43cfba9b437b0e580687837 465 PANTHER PTHR31302 221 464 5.8E-47 T 22-04-2016 HRM2_RS11770 e0391c94c43cfba9b437b0e580687837 465 Pfam PF00149 Calcineurin-like phosphoesterase 242 401 2.4E-8 T 22-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 HRM2_RS19065 d2806aefc2ad13f6d14ce8d5ba765178 73 Pfam PF00364 Biotin-requiring enzyme 4 70 4.0E-17 T 22-04-2016 IPR000089 Biotin/lipoyl attachment HRM2_RS19065 d2806aefc2ad13f6d14ce8d5ba765178 73 PANTHER PTHR18866 2 73 1.3E-13 T 22-04-2016 HRM2_RS19065 d2806aefc2ad13f6d14ce8d5ba765178 73 PANTHER PTHR18866:SF102 2 73 1.3E-13 T 22-04-2016 HRM2_RS19065 d2806aefc2ad13f6d14ce8d5ba765178 73 SUPERFAMILY SSF51230 4 71 3.93E-20 T 22-04-2016 IPR011053 Single hybrid motif HRM2_RS19065 d2806aefc2ad13f6d14ce8d5ba765178 73 Gene3D G3DSA:2.40.50.100 3 71 6.3E-22 T 22-04-2016 HRM2_RS19000 d2806aefc2ad13f6d14ce8d5ba765178 73 Pfam PF00364 Biotin-requiring enzyme 4 70 4.0E-17 T 22-04-2016 IPR000089 Biotin/lipoyl attachment HRM2_RS19000 d2806aefc2ad13f6d14ce8d5ba765178 73 PANTHER PTHR18866 2 73 1.3E-13 T 22-04-2016 HRM2_RS19000 d2806aefc2ad13f6d14ce8d5ba765178 73 PANTHER PTHR18866:SF102 2 73 1.3E-13 T 22-04-2016 HRM2_RS19000 d2806aefc2ad13f6d14ce8d5ba765178 73 SUPERFAMILY SSF51230 4 71 3.93E-20 T 22-04-2016 IPR011053 Single hybrid motif HRM2_RS19000 d2806aefc2ad13f6d14ce8d5ba765178 73 Gene3D G3DSA:2.40.50.100 3 71 6.3E-22 T 22-04-2016 HRM2_RS04830 cc8d0f93d2f2a51594613e8a5e8f0654 357 SUPERFAMILY SSF54197 182 355 1.19E-26 T 22-04-2016 IPR011146 HIT-like domain GO:0003824 HRM2_RS04830 cc8d0f93d2f2a51594613e8a5e8f0654 357 PIRSF PIRSF000808 1 357 3.5E-90 T 22-04-2016 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HRM2_RS04830 cc8d0f93d2f2a51594613e8a5e8f0654 357 Gene3D G3DSA:3.30.428.10 48 178 1.2E-40 T 22-04-2016 IPR011146 HIT-like domain GO:0003824 HRM2_RS04830 cc8d0f93d2f2a51594613e8a5e8f0654 357 PANTHER PTHR11943 8 210 1.6E-88 T 22-04-2016 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HRM2_RS04830 cc8d0f93d2f2a51594613e8a5e8f0654 357 PANTHER PTHR11943 233 357 1.6E-88 T 22-04-2016 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HRM2_RS04830 cc8d0f93d2f2a51594613e8a5e8f0654 357 PANTHER PTHR11943:SF3 8 210 1.6E-88 T 22-04-2016 HRM2_RS04830 cc8d0f93d2f2a51594613e8a5e8f0654 357 PANTHER PTHR11943:SF3 233 357 1.6E-88 T 22-04-2016 HRM2_RS04830 cc8d0f93d2f2a51594613e8a5e8f0654 357 SUPERFAMILY SSF54197 5 179 1.84E-37 T 22-04-2016 IPR011146 HIT-like domain GO:0003824 HRM2_RS04830 cc8d0f93d2f2a51594613e8a5e8f0654 357 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 102 179 3.3E-10 T 22-04-2016 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HRM2_RS04830 cc8d0f93d2f2a51594613e8a5e8f0654 357 Gene3D G3DSA:3.30.428.10 180 355 6.8E-38 T 22-04-2016 IPR011146 HIT-like domain GO:0003824 HRM2_RS11745 4fe9eb31c6f58a86509fb3ed1bd764ee 351 PANTHER PTHR13696 99 344 1.2E-47 T 22-04-2016 HRM2_RS11745 4fe9eb31c6f58a86509fb3ed1bd764ee 351 SUPERFAMILY SSF52540 101 343 4.96E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11745 4fe9eb31c6f58a86509fb3ed1bd764ee 351 Gene3D G3DSA:3.40.50.300 102 344 7.0E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11745 4fe9eb31c6f58a86509fb3ed1bd764ee 351 PANTHER PTHR13696:SF52 99 344 1.2E-47 T 22-04-2016 HRM2_RS11745 4fe9eb31c6f58a86509fb3ed1bd764ee 351 Pfam PF13614 AAA domain 102 267 1.2E-33 T 22-04-2016 IPR025669 AAA domain HRM2_RS22185 4c7fab6ba54dacca194ca91da60c1f5c 227 Gene3D G3DSA:1.20.950.20 172 210 9.9E-5 T 22-04-2016 HRM2_RS22185 4c7fab6ba54dacca194ca91da60c1f5c 227 Gene3D G3DSA:1.20.950.20 4 36 1.5E-14 T 22-04-2016 HRM2_RS22185 4c7fab6ba54dacca194ca91da60c1f5c 227 Gene3D G3DSA:1.20.950.20 69 170 1.5E-14 T 22-04-2016 HRM2_RS22185 4c7fab6ba54dacca194ca91da60c1f5c 227 SUPERFAMILY SSF103501 5 26 5.36E-25 T 22-04-2016 IPR023234 NarG-like domain HRM2_RS22185 4c7fab6ba54dacca194ca91da60c1f5c 227 SUPERFAMILY SSF103501 63 210 5.36E-25 T 22-04-2016 IPR023234 NarG-like domain HRM2_RS21680 9bcbe03d364fe9070f196831912b3ae9 294 PANTHER PTHR21091 3 293 9.8E-50 T 22-04-2016 HRM2_RS21680 9bcbe03d364fe9070f196831912b3ae9 294 Gene3D G3DSA:3.20.20.330 3 293 3.0E-82 T 22-04-2016 IPR003726 Homocysteine-binding domain HRM2_RS21680 9bcbe03d364fe9070f196831912b3ae9 294 Pfam PF02574 Homocysteine S-methyltransferase 12 291 3.7E-60 T 22-04-2016 IPR003726 Homocysteine-binding domain HRM2_RS21680 9bcbe03d364fe9070f196831912b3ae9 294 SUPERFAMILY SSF82282 3 293 2.88E-82 T 22-04-2016 IPR003726 Homocysteine-binding domain HRM2_RS21680 9bcbe03d364fe9070f196831912b3ae9 294 PIRSF PIRSF037505 3 294 2.5E-16 T 22-04-2016 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 UniPathway: UPA00051 HRM2_RS21680 9bcbe03d364fe9070f196831912b3ae9 294 PANTHER PTHR21091:SF97 3 293 9.8E-50 T 22-04-2016 HRM2_RS22665 ea7678ec3cdf62fa962cf7aa4d8cdf75 268 PANTHER PTHR10108 5 175 2.7E-26 T 22-04-2016 HRM2_RS22665 ea7678ec3cdf62fa962cf7aa4d8cdf75 268 Gene3D G3DSA:3.40.50.150 10 175 1.5E-33 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS22665 ea7678ec3cdf62fa962cf7aa4d8cdf75 268 SUPERFAMILY SSF53335 5 177 1.33E-33 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS22665 ea7678ec3cdf62fa962cf7aa4d8cdf75 268 Pfam PF08241 Methyltransferase domain 46 132 3.3E-20 T 22-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 HRM2_RS04430 066b87053cf3986014d4d8fb74ec41a0 330 PANTHER PTHR11082 1 325 3.1E-121 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 HRM2_RS04430 066b87053cf3986014d4d8fb74ec41a0 330 Pfam PF01207 Dihydrouridine synthase (Dus) 13 313 9.2E-86 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 HRM2_RS04430 066b87053cf3986014d4d8fb74ec41a0 330 PIRSF PIRSF006621 1 328 2.2E-93 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 HRM2_RS04430 066b87053cf3986014d4d8fb74ec41a0 330 PANTHER PTHR11082:SF25 1 325 3.1E-121 T 22-04-2016 HRM2_RS04430 066b87053cf3986014d4d8fb74ec41a0 330 Gene3D G3DSA:3.20.20.70 7 245 3.5E-81 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS04430 066b87053cf3986014d4d8fb74ec41a0 330 SUPERFAMILY SSF51395 11 317 4.58E-85 T 22-04-2016 HRM2_RS04430 066b87053cf3986014d4d8fb74ec41a0 330 Gene3D G3DSA:1.10.1200.80 252 324 1.6E-15 T 22-04-2016 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 HRM2_RS04430 066b87053cf3986014d4d8fb74ec41a0 330 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 3 318 1.6E-102 T 22-04-2016 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 HRM2_RS10515 0f7bb88dc5289dabddf9b4741a43cd96 205 Gene3D G3DSA:1.10.3450.10 52 155 2.6E-13 T 22-04-2016 IPR023203 TTHA0068-like domain HRM2_RS10515 0f7bb88dc5289dabddf9b4741a43cd96 205 Pfam PF03745 Domain of unknown function (DUF309) 94 146 5.5E-13 T 22-04-2016 IPR005500 Protein of unknown function DUF309 HRM2_RS10515 0f7bb88dc5289dabddf9b4741a43cd96 205 SUPERFAMILY SSF140663 71 180 7.46E-16 T 22-04-2016 IPR023203 TTHA0068-like domain HRM2_RS04155 1e1b6272b3be9736993b9ea748f0ac56 436 PANTHER PTHR33171:SF3 1 380 1.4E-52 T 22-04-2016 HRM2_RS04155 1e1b6272b3be9736993b9ea748f0ac56 436 Pfam PF09861 Domain of unknown function (DUF2088) 8 201 1.1E-43 T 22-04-2016 IPR018657 Domain of unknown function DUF2088 HRM2_RS04155 1e1b6272b3be9736993b9ea748f0ac56 436 PANTHER PTHR33171 1 380 1.4E-52 T 22-04-2016 HRM2_RS07850 d250dbba088075f2a89398859fa061f4 311 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 40 275 2.5E-15 T 22-04-2016 HRM2_RS07850 d250dbba088075f2a89398859fa061f4 311 SUPERFAMILY SSF53850 48 249 9.19E-8 T 22-04-2016 HRM2_RS07850 d250dbba088075f2a89398859fa061f4 311 Gene3D G3DSA:3.40.190.10 123 231 7.4E-6 T 22-04-2016 HRM2_RS07520 3a7e6d7c19ed8c7ddf1757392ab9a7cc 457 SUPERFAMILY SSF81442 14 453 4.71E-83 T 22-04-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 HRM2_RS07520 3a7e6d7c19ed8c7ddf1757392ab9a7cc 457 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 18 432 1.1E-74 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 HRM2_RS07520 3a7e6d7c19ed8c7ddf1757392ab9a7cc 457 Gene3D G3DSA:1.20.210.10 18 452 1.5E-41 T 22-04-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 HRM2_RS07520 3a7e6d7c19ed8c7ddf1757392ab9a7cc 457 PANTHER PTHR10422 17 407 4.5E-62 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 HRM2_RS07520 3a7e6d7c19ed8c7ddf1757392ab9a7cc 457 PANTHER PTHR10422:SF21 17 407 4.5E-62 T 22-04-2016 HRM2_RS10890 1ae2e7b7b2ae24e057970a2eeca81f1d 149 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 3 146 2.3E-47 T 22-04-2016 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 HRM2_RS10890 1ae2e7b7b2ae24e057970a2eeca81f1d 149 PANTHER PTHR33371 1 145 4.1E-36 T 22-04-2016 HRM2_RS10890 1ae2e7b7b2ae24e057970a2eeca81f1d 149 Pfam PF02470 MlaD protein 37 115 1.0E-22 T 22-04-2016 IPR003399 Mce/MlaD HRM2_RS22280 ee1b958f1fd279609500b5a339ef100c 180 Pfam PF13689 Domain of unknown function (DUF4154) 29 172 2.1E-43 T 22-04-2016 IPR025293 Protein of unknown function DUF4154 HRM2_RS13455 a16011de261366bcb640ae50aba9344b 83 Pfam PF01649 Ribosomal protein S20 2 82 1.9E-26 T 22-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS13455 a16011de261366bcb640ae50aba9344b 83 SUPERFAMILY SSF46992 3 82 2.49E-25 T 22-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS13455 a16011de261366bcb640ae50aba9344b 83 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 12 80 5.0E-7 T 22-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS13455 a16011de261366bcb640ae50aba9344b 83 PANTHER PTHR33398 2 80 9.7E-25 T 22-04-2016 HRM2_RS13455 a16011de261366bcb640ae50aba9344b 83 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 83 14.845 T 22-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS13455 a16011de261366bcb640ae50aba9344b 83 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 82 1.7E-22 T 22-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS13455 a16011de261366bcb640ae50aba9344b 83 Gene3D G3DSA:1.20.58.110 1 81 3.4E-27 T 22-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS05915 405bc8d614b42b0ca5ff96c966feddd6 102 Gene3D G3DSA:3.30.110.60 3 98 4.6E-24 T 22-04-2016 IPR001890 RNA-binding, CRM domain GO:0003723 HRM2_RS05915 405bc8d614b42b0ca5ff96c966feddd6 102 Pfam PF01985 CRS1 / YhbY (CRM) domain 4 88 2.3E-18 T 22-04-2016 IPR001890 RNA-binding, CRM domain GO:0003723 HRM2_RS05915 405bc8d614b42b0ca5ff96c966feddd6 102 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 11 101 8.0E-20 T 22-04-2016 IPR001890 RNA-binding, CRM domain GO:0003723 HRM2_RS05915 405bc8d614b42b0ca5ff96c966feddd6 102 SMART SM01103 4 88 4.2E-25 T 22-04-2016 IPR001890 RNA-binding, CRM domain GO:0003723 HRM2_RS05915 405bc8d614b42b0ca5ff96c966feddd6 102 PANTHER PTHR31846 8 102 2.4E-12 T 22-04-2016 HRM2_RS05915 405bc8d614b42b0ca5ff96c966feddd6 102 SUPERFAMILY SSF75471 4 98 1.12E-22 T 22-04-2016 IPR001890 RNA-binding, CRM domain GO:0003723 HRM2_RS13800 25d7fde18c9e28737439daa4d52f9276 179 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 4 93 1.8E-21 T 22-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 HRM2_RS13800 25d7fde18c9e28737439daa4d52f9276 179 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 98 1.8E-21 T 22-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 HRM2_RS13800 25d7fde18c9e28737439daa4d52f9276 179 SUPERFAMILY SSF69754 4 99 2.22E-26 T 22-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 HRM2_RS13800 25d7fde18c9e28737439daa4d52f9276 179 Gene3D G3DSA:3.30.160.100 1 95 5.1E-26 T 22-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 HRM2_RS13800 25d7fde18c9e28737439daa4d52f9276 179 PANTHER PTHR33231 1 179 2.7E-37 T 22-04-2016 HRM2_RS13800 25d7fde18c9e28737439daa4d52f9276 179 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 127 174 2.0E-17 T 22-04-2016 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal HRM2_RS04970 42d1fd1c2190260a2c917a654fdb53c2 279 Gene3D G3DSA:3.40.50.300 1 184 9.0E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS04970 42d1fd1c2190260a2c917a654fdb53c2 279 Pfam PF13189 Cytidylate kinase-like family 3 167 2.3E-35 T 22-04-2016 IPR026865 Cytidylate kinase-like family MetaCyc: PWY-7205 HRM2_RS03365 ff8a4ef46c2aee79c1991d2c97882cdc 250 SMART SM00900 120 223 4.1E-17 T 22-04-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 HRM2_RS03365 ff8a4ef46c2aee79c1991d2c97882cdc 250 PANTHER PTHR37838:SF1 1 241 1.7E-40 T 22-04-2016 HRM2_RS03365 ff8a4ef46c2aee79c1991d2c97882cdc 250 Hamap MF_00427 Na(+)-translocating NADH-quinone reductase subunit C [nqrC]. 9 225 25.958 T 22-04-2016 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 HRM2_RS03365 ff8a4ef46c2aee79c1991d2c97882cdc 250 PANTHER PTHR37838 1 241 1.7E-40 T 22-04-2016 HRM2_RS03365 ff8a4ef46c2aee79c1991d2c97882cdc 250 Pfam PF04205 FMN-binding domain 120 218 4.1E-14 T 22-04-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 HRM2_RS22680 da59825d9c6032a6cfe3dfeaa4f18612 202 SUPERFAMILY SSF52507 5 198 1.7E-53 T 22-04-2016 IPR003382 Flavoprotein GO:0003824 HRM2_RS22680 da59825d9c6032a6cfe3dfeaa4f18612 202 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 3 199 34.65 T 22-04-2016 IPR004507 Flavin prenyltransferase UbiX/Pad1 HRM2_RS22680 da59825d9c6032a6cfe3dfeaa4f18612 202 Gene3D G3DSA:3.40.50.1950 5 198 3.5E-67 T 22-04-2016 IPR003382 Flavoprotein GO:0003824 HRM2_RS22680 da59825d9c6032a6cfe3dfeaa4f18612 202 PANTHER PTHR30108 66 197 6.8E-72 T 22-04-2016 HRM2_RS22680 da59825d9c6032a6cfe3dfeaa4f18612 202 PANTHER PTHR30108 5 50 6.8E-72 T 22-04-2016 HRM2_RS22680 da59825d9c6032a6cfe3dfeaa4f18612 202 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 5 197 4.4E-61 T 22-04-2016 IPR004507 Flavin prenyltransferase UbiX/Pad1 HRM2_RS22680 da59825d9c6032a6cfe3dfeaa4f18612 202 PANTHER PTHR30108:SF2 66 197 6.8E-72 T 22-04-2016 HRM2_RS22680 da59825d9c6032a6cfe3dfeaa4f18612 202 PANTHER PTHR30108:SF2 5 50 6.8E-72 T 22-04-2016 HRM2_RS22680 da59825d9c6032a6cfe3dfeaa4f18612 202 Pfam PF02441 Flavoprotein 5 140 2.6E-25 T 22-04-2016 IPR003382 Flavoprotein GO:0003824 HRM2_RS11500 eb4e60d526df0d892d1cf9d7685ce00d 434 SUPERFAMILY SSF52540 72 355 2.8E-74 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11500 eb4e60d526df0d892d1cf9d7685ce00d 434 Pfam PF00270 DEAD/DEAH box helicase 25 194 2.0E-50 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HRM2_RS11500 eb4e60d526df0d892d1cf9d7685ce00d 434 SMART SM00487 20 221 1.2E-58 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS11500 eb4e60d526df0d892d1cf9d7685ce00d 434 Pfam PF00271 Helicase conserved C-terminal domain 230 338 1.1E-27 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS11500 eb4e60d526df0d892d1cf9d7685ce00d 434 Gene3D G3DSA:3.40.50.300 1 210 1.5E-76 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11500 eb4e60d526df0d892d1cf9d7685ce00d 434 SMART SM00490 257 338 2.2E-32 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS11500 eb4e60d526df0d892d1cf9d7685ce00d 434 PANTHER PTHR24031:SF0 1 366 1.7E-172 T 22-04-2016 HRM2_RS11500 eb4e60d526df0d892d1cf9d7685ce00d 434 PANTHER PTHR24031 1 366 1.7E-172 T 22-04-2016 HRM2_RS11500 eb4e60d526df0d892d1cf9d7685ce00d 434 Gene3D G3DSA:3.40.50.300 211 368 1.3E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11500 eb4e60d526df0d892d1cf9d7685ce00d 434 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 152 160 - T 22-04-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site HRM2_RS22605 1315a0243dac1a0dd02f98318ef854e7 465 Pfam PF00158 Sigma-54 interaction domain 142 309 8.0E-66 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS22605 1315a0243dac1a0dd02f98318ef854e7 465 Gene3D G3DSA:3.40.50.300 140 315 7.5E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22605 1315a0243dac1a0dd02f98318ef854e7 465 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 229 244 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS22605 1315a0243dac1a0dd02f98318ef854e7 465 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 167 180 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS22605 1315a0243dac1a0dd02f98318ef854e7 465 SUPERFAMILY SSF52540 141 386 1.26E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22605 1315a0243dac1a0dd02f98318ef854e7 465 SUPERFAMILY SSF52172 3 187 3.7E-43 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS22605 1315a0243dac1a0dd02f98318ef854e7 465 SUPERFAMILY SSF46689 356 465 3.18E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS22605 1315a0243dac1a0dd02f98318ef854e7 465 Gene3D G3DSA:1.10.8.60 316 387 8.3E-23 T 22-04-2016 HRM2_RS22605 1315a0243dac1a0dd02f98318ef854e7 465 Gene3D G3DSA:1.10.10.60 407 465 1.4E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS22605 1315a0243dac1a0dd02f98318ef854e7 465 Pfam PF00072 Response regulator receiver domain 4 113 3.7E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS22605 1315a0243dac1a0dd02f98318ef854e7 465 SMART SM00382 163 325 4.4E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS22605 1315a0243dac1a0dd02f98318ef854e7 465 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 356 365 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS22605 1315a0243dac1a0dd02f98318ef854e7 465 PANTHER PTHR32071 1 465 2.0E-180 T 22-04-2016 HRM2_RS22605 1315a0243dac1a0dd02f98318ef854e7 465 SMART SM00448 2 113 1.6E-35 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS22605 1315a0243dac1a0dd02f98318ef854e7 465 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 446 465 2.0E-7 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS22605 1315a0243dac1a0dd02f98318ef854e7 465 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 429 446 2.0E-7 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS22605 1315a0243dac1a0dd02f98318ef854e7 465 Pfam PF02954 Bacterial regulatory protein, Fis family 423 462 3.5E-11 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS22605 1315a0243dac1a0dd02f98318ef854e7 465 Gene3D G3DSA:3.40.50.2300 1 127 1.4E-36 T 22-04-2016 HRM2_RS13265 526834bf635bdbeb71632a2e40c45835 345 Pfam PF13177 DNA polymerase III, delta subunit 24 176 1.7E-48 T 22-04-2016 HRM2_RS13265 526834bf635bdbeb71632a2e40c45835 345 SUPERFAMILY SSF52540 25 211 5.46E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13265 526834bf635bdbeb71632a2e40c45835 345 PANTHER PTHR11669 21 213 4.9E-55 T 22-04-2016 HRM2_RS13265 526834bf635bdbeb71632a2e40c45835 345 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 26 210 1.4E-58 T 22-04-2016 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS13265 526834bf635bdbeb71632a2e40c45835 345 Gene3D G3DSA:3.40.50.300 21 175 1.3E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13265 526834bf635bdbeb71632a2e40c45835 345 PANTHER PTHR11669:SF8 21 213 4.9E-55 T 22-04-2016 HRM2_RS11125 1c28d52f1b180eaadb27e9218b7ceb34 271 PANTHER PTHR39962 1 270 4.3E-74 T 22-04-2016 HRM2_RS11125 1c28d52f1b180eaadb27e9218b7ceb34 271 Pfam PF06230 Protein of unknown function (DUF1009) 56 263 2.6E-74 T 22-04-2016 IPR010415 Protein of unknown function DUF1009 HRM2_RS11125 1c28d52f1b180eaadb27e9218b7ceb34 271 PANTHER PTHR39962:SF1 1 270 4.3E-74 T 22-04-2016 HRM2_RS15490 c73fc2a164bf6d0894b1f20f3f850f11 220 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 31 194 1.9E-23 T 22-04-2016 IPR003495 CobW/HypB/UreG, nucleotide-binding domain HRM2_RS15490 c73fc2a164bf6d0894b1f20f3f850f11 220 Gene3D G3DSA:3.40.50.300 172 216 3.5E-5 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS15490 c73fc2a164bf6d0894b1f20f3f850f11 220 PIRSF PIRSF005624 1 219 2.8E-81 T 22-04-2016 HRM2_RS15490 c73fc2a164bf6d0894b1f20f3f850f11 220 PANTHER PTHR30134 3 216 1.4E-99 T 22-04-2016 HRM2_RS15490 c73fc2a164bf6d0894b1f20f3f850f11 220 SUPERFAMILY SSF52540 6 215 1.41E-30 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS15490 c73fc2a164bf6d0894b1f20f3f850f11 220 TIGRFAM TIGR00073 hypB: hydrogenase accessory protein HypB 3 217 5.1E-78 T 22-04-2016 IPR004392 Hydrogenase accessory protein HypB GO:0006461|GO:0016151 HRM2_RS15490 c73fc2a164bf6d0894b1f20f3f850f11 220 Gene3D G3DSA:3.40.50.300 27 171 5.1E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS15490 c73fc2a164bf6d0894b1f20f3f850f11 220 PANTHER PTHR30134:SF2 3 216 1.4E-99 T 22-04-2016 HRM2_RS12800 10f24a1dcc51a730d1d04a0fe8292dd8 771 SUPERFAMILY SSF82866 564 760 7.46E-27 T 22-04-2016 HRM2_RS12800 10f24a1dcc51a730d1d04a0fe8292dd8 771 Pfam PF03176 MMPL family 548 759 1.7E-8 T 22-04-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 HRM2_RS12800 10f24a1dcc51a730d1d04a0fe8292dd8 771 Pfam PF03176 MMPL family 121 362 5.0E-7 T 22-04-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 HRM2_RS12800 10f24a1dcc51a730d1d04a0fe8292dd8 771 PRINTS PR00702 Acriflavin resistance protein family signature 654 678 1.4E-6 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS12800 10f24a1dcc51a730d1d04a0fe8292dd8 771 PRINTS PR00702 Acriflavin resistance protein family signature 248 272 1.4E-6 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS12800 10f24a1dcc51a730d1d04a0fe8292dd8 771 PRINTS PR00702 Acriflavin resistance protein family signature 599 622 1.4E-6 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS12800 10f24a1dcc51a730d1d04a0fe8292dd8 771 PRINTS PR00702 Acriflavin resistance protein family signature 732 755 1.4E-6 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HRM2_RS12800 10f24a1dcc51a730d1d04a0fe8292dd8 771 PANTHER PTHR33406 5 758 1.1E-31 T 22-04-2016 HRM2_RS12800 10f24a1dcc51a730d1d04a0fe8292dd8 771 SUPERFAMILY SSF82866 183 368 4.84E-20 T 22-04-2016 HRM2_RS12800 10f24a1dcc51a730d1d04a0fe8292dd8 771 Gene3D G3DSA:1.20.1640.10 555 766 2.9E-25 T 22-04-2016 HRM2_RS12800 10f24a1dcc51a730d1d04a0fe8292dd8 771 Gene3D G3DSA:1.20.1640.10 224 366 7.7E-22 T 22-04-2016 HRM2_RS07530 0535bbbe97274fc47f1dd16af6ddd92c 418 PANTHER PTHR34856:SF4 3 404 5.4E-39 T 22-04-2016 HRM2_RS07530 0535bbbe97274fc47f1dd16af6ddd92c 418 Pfam PF03916 Polysulphide reductase, NrfD 52 366 1.0E-4 T 22-04-2016 IPR005614 NrfD family HRM2_RS07530 0535bbbe97274fc47f1dd16af6ddd92c 418 PANTHER PTHR34856 3 404 5.4E-39 T 22-04-2016 HRM2_RS12170 8237ce9ee15098e3999ef657e852f81e 149 PANTHER PTHR34801 1 141 3.2E-45 T 22-04-2016 HRM2_RS12170 8237ce9ee15098e3999ef657e852f81e 149 PIRSF PIRSF026426 1 146 2.7E-46 T 22-04-2016 IPR010865 Protein of unknown function DUF1499 HRM2_RS12170 8237ce9ee15098e3999ef657e852f81e 149 Pfam PF07386 Protein of unknown function (DUF1499) 29 139 7.3E-33 T 22-04-2016 IPR010865 Protein of unknown function DUF1499 HRM2_RS07665 d24624ef97bf16a698d46d36922596da 388 Pfam PF00465 Iron-containing alcohol dehydrogenase 13 380 3.8E-122 T 22-04-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 HRM2_RS07665 d24624ef97bf16a698d46d36922596da 388 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 265 285 - T 22-04-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 HRM2_RS07665 d24624ef97bf16a698d46d36922596da 388 Gene3D G3DSA:1.20.1090.10 190 388 1.9E-77 T 22-04-2016 HRM2_RS07665 d24624ef97bf16a698d46d36922596da 388 PANTHER PTHR11496:SF78 7 388 5.3E-174 T 22-04-2016 HRM2_RS07665 d24624ef97bf16a698d46d36922596da 388 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 178 206 - T 22-04-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 HRM2_RS07665 d24624ef97bf16a698d46d36922596da 388 PANTHER PTHR11496 7 388 5.3E-174 T 22-04-2016 HRM2_RS07665 d24624ef97bf16a698d46d36922596da 388 SUPERFAMILY SSF56796 8 387 5.89E-132 T 22-04-2016 HRM2_RS07665 d24624ef97bf16a698d46d36922596da 388 Gene3D G3DSA:3.40.50.1970 10 189 5.9E-57 T 22-04-2016 HRM2_RS07670 751e36b99ae52ea25e2a87006aa6e7b3 452 Gene3D G3DSA:3.40.50.2300 7 133 2.6E-34 T 22-04-2016 HRM2_RS07670 751e36b99ae52ea25e2a87006aa6e7b3 452 Gene3D G3DSA:3.40.50.300 147 317 2.2E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07670 751e36b99ae52ea25e2a87006aa6e7b3 452 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 433 452 3.4E-7 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS07670 751e36b99ae52ea25e2a87006aa6e7b3 452 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 416 433 3.4E-7 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS07670 751e36b99ae52ea25e2a87006aa6e7b3 452 PANTHER PTHR32071 8 447 1.1E-175 T 22-04-2016 HRM2_RS07670 751e36b99ae52ea25e2a87006aa6e7b3 452 Pfam PF02954 Bacterial regulatory protein, Fis family 409 447 1.0E-14 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS07670 751e36b99ae52ea25e2a87006aa6e7b3 452 SMART SM00382 169 313 6.9E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS07670 751e36b99ae52ea25e2a87006aa6e7b3 452 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 360 369 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS07670 751e36b99ae52ea25e2a87006aa6e7b3 452 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 235 250 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HRM2_RS07670 751e36b99ae52ea25e2a87006aa6e7b3 452 Pfam PF00158 Sigma-54 interaction domain 149 315 6.1E-61 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS07670 751e36b99ae52ea25e2a87006aa6e7b3 452 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 173 186 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 HRM2_RS07670 751e36b99ae52ea25e2a87006aa6e7b3 452 Pfam PF00072 Response regulator receiver domain 10 119 1.8E-26 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS07670 751e36b99ae52ea25e2a87006aa6e7b3 452 SUPERFAMILY SSF52172 7 193 2.99E-41 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS07670 751e36b99ae52ea25e2a87006aa6e7b3 452 Gene3D G3DSA:1.10.10.60 407 447 8.8E-18 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS07670 751e36b99ae52ea25e2a87006aa6e7b3 452 SMART SM00448 8 119 6.9E-32 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS07670 751e36b99ae52ea25e2a87006aa6e7b3 452 Gene3D G3DSA:1.10.8.60 321 396 7.4E-22 T 22-04-2016 HRM2_RS07670 751e36b99ae52ea25e2a87006aa6e7b3 452 SUPERFAMILY SSF52540 148 389 7.1E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07670 751e36b99ae52ea25e2a87006aa6e7b3 452 SUPERFAMILY SSF46689 360 447 1.79E-16 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS12490 a275e267402f0950361184d71c7aeec8 337 Gene3D G3DSA:3.40.47.10 165 335 1.2E-44 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS12490 a275e267402f0950361184d71c7aeec8 337 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 246 335 4.7E-31 T 22-04-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 HRM2_RS12490 a275e267402f0950361184d71c7aeec8 337 SUPERFAMILY SSF53901 5 336 2.99E-63 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS12490 a275e267402f0950361184d71c7aeec8 337 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 2 336 57.231 T 22-04-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 HRM2_RS12490 a275e267402f0950361184d71c7aeec8 337 PANTHER PTHR34069:SF2 1 335 1.3E-106 T 22-04-2016 HRM2_RS12490 a275e267402f0950361184d71c7aeec8 337 Gene3D G3DSA:3.40.47.10 1 164 1.2E-54 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS12490 a275e267402f0950361184d71c7aeec8 337 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 109 191 2.2E-23 T 22-04-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 HRM2_RS12490 a275e267402f0950361184d71c7aeec8 337 PANTHER PTHR34069 1 335 1.3E-106 T 22-04-2016 HRM2_RS12490 a275e267402f0950361184d71c7aeec8 337 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 4 336 4.4E-102 T 22-04-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 HRM2_RS20635 a3d9703da037d0fcfa6d4615d33bb7f4 256 Pfam PF03883 Protein of unknown function (DUF328) 1 242 6.0E-67 T 22-04-2016 IPR005583 Peroxide stress protein YaaA HRM2_RS20635 a3d9703da037d0fcfa6d4615d33bb7f4 256 PANTHER PTHR30283 2 255 2.3E-64 T 22-04-2016 HRM2_RS20635 a3d9703da037d0fcfa6d4615d33bb7f4 256 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 256 27.803 T 22-04-2016 IPR005583 Peroxide stress protein YaaA HRM2_RS20635 a3d9703da037d0fcfa6d4615d33bb7f4 256 PANTHER PTHR30283:SF3 2 255 2.3E-64 T 22-04-2016 HRM2_RS06630 20f1e256091af76a433972f1b15e1b39 92 Hamap MF_01396 ATP synthase subunit c [atpH]. 11 79 14.699 T 22-04-2016 HRM2_RS06630 20f1e256091af76a433972f1b15e1b39 92 Pfam PF00137 ATP synthase subunit C 14 76 1.5E-14 T 22-04-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 HRM2_RS06630 20f1e256091af76a433972f1b15e1b39 92 PANTHER PTHR10031 6 80 2.1E-13 T 22-04-2016 HRM2_RS06630 20f1e256091af76a433972f1b15e1b39 92 PRINTS PR00124 ATP synthase C subunit signature 35 50 2.3E-11 T 22-04-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 HRM2_RS06630 20f1e256091af76a433972f1b15e1b39 92 PRINTS PR00124 ATP synthase C subunit signature 14 33 2.3E-11 T 22-04-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 HRM2_RS06630 20f1e256091af76a433972f1b15e1b39 92 PRINTS PR00124 ATP synthase C subunit signature 52 77 2.3E-11 T 22-04-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 HRM2_RS06630 20f1e256091af76a433972f1b15e1b39 92 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 23 79 7.6E-15 T 22-04-2016 IPR005953 ATPase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 HRM2_RS06630 20f1e256091af76a433972f1b15e1b39 92 SUPERFAMILY SSF81333 8 81 2.62E-16 T 22-04-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 HRM2_RS06630 20f1e256091af76a433972f1b15e1b39 92 Gene3D G3DSA:1.20.20.10 11 78 4.4E-20 T 22-04-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 HRM2_RS05755 56c065cb3c5c9235582663967142b858 462 Gene3D G3DSA:3.40.605.10 5 229 2.0E-59 T 22-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 HRM2_RS05755 56c065cb3c5c9235582663967142b858 462 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 242 253 - T 22-04-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 HRM2_RS05755 56c065cb3c5c9235582663967142b858 462 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 214 221 - T 22-04-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 HRM2_RS05755 56c065cb3c5c9235582663967142b858 462 PANTHER PTHR11699:SF15 1 461 3.2E-200 T 22-04-2016 HRM2_RS05755 56c065cb3c5c9235582663967142b858 462 SUPERFAMILY SSF53720 9 451 1.7E-124 T 22-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 HRM2_RS05755 56c065cb3c5c9235582663967142b858 462 Pfam PF00171 Aldehyde dehydrogenase family 8 433 1.3E-90 T 22-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 HRM2_RS05755 56c065cb3c5c9235582663967142b858 462 PIRSF PIRSF036492 1 462 1.4E-178 T 22-04-2016 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 HRM2_RS05755 56c065cb3c5c9235582663967142b858 462 Gene3D G3DSA:3.40.309.10 230 414 1.3E-60 T 22-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 HRM2_RS05755 56c065cb3c5c9235582663967142b858 462 PANTHER PTHR11699 1 461 3.2E-200 T 22-04-2016 HRM2_RS06795 f0bb32d2c3e8c4af83556263917b8e44 499 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 375 484 1.7E-19 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS06795 f0bb32d2c3e8c4af83556263917b8e44 499 SMART SM00387 374 486 9.7E-23 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS06795 f0bb32d2c3e8c4af83556263917b8e44 499 Gene3D G3DSA:3.30.565.10 333 484 2.0E-32 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS06795 f0bb32d2c3e8c4af83556263917b8e44 499 SUPERFAMILY SSF55785 139 251 6.28E-12 T 22-04-2016 IPR000014 PAS domain HRM2_RS06795 f0bb32d2c3e8c4af83556263917b8e44 499 SUPERFAMILY SSF55874 333 484 8.77E-31 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS06795 f0bb32d2c3e8c4af83556263917b8e44 499 SUPERFAMILY SSF52172 45 121 2.41E-5 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS06795 f0bb32d2c3e8c4af83556263917b8e44 499 Gene3D G3DSA:3.40.50.2300 46 125 3.5E-4 T 22-04-2016 HRM2_RS06795 f0bb32d2c3e8c4af83556263917b8e44 499 Pfam PF08448 PAS fold 149 254 8.8E-7 T 22-04-2016 IPR013656 PAS fold-4 HRM2_RS06795 f0bb32d2c3e8c4af83556263917b8e44 499 PANTHER PTHR24423 141 488 9.6E-57 T 22-04-2016 HRM2_RS06795 f0bb32d2c3e8c4af83556263917b8e44 499 Gene3D G3DSA:3.30.450.20 140 251 5.6E-13 T 22-04-2016 HRM2_RS06795 f0bb32d2c3e8c4af83556263917b8e44 499 PRINTS PR00344 Bacterial sensor protein C-terminal signature 470 483 1.0E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS06795 f0bb32d2c3e8c4af83556263917b8e44 499 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 444 1.0E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS06795 f0bb32d2c3e8c4af83556263917b8e44 499 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 430 1.0E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS06795 f0bb32d2c3e8c4af83556263917b8e44 499 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 464 1.0E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS09030 5f8052a12141d61daa50c6f6ee9884c7 395 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 33 338 6.1E-69 T 22-04-2016 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130|UniPathway: UPA00359 HRM2_RS09030 5f8052a12141d61daa50c6f6ee9884c7 395 PANTHER PTHR30160 1 380 3.6E-82 T 22-04-2016 HRM2_RS09030 5f8052a12141d61daa50c6f6ee9884c7 395 SUPERFAMILY SSF52540 60 178 2.17E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09030 5f8052a12141d61daa50c6f6ee9884c7 395 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 8 371 29.123 T 22-04-2016 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130|UniPathway: UPA00359 HRM2_RS09030 5f8052a12141d61daa50c6f6ee9884c7 395 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 27 358 4.6E-89 T 22-04-2016 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130|UniPathway: UPA00359 HRM2_RS09030 5f8052a12141d61daa50c6f6ee9884c7 395 PANTHER PTHR30160:SF13 1 380 3.6E-82 T 22-04-2016 HRM2_RS13280 098939e3da6383fe4e425e63f2b9970d 372 Gene3D G3DSA:3.40.710.10 28 359 1.9E-53 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HRM2_RS13280 098939e3da6383fe4e425e63f2b9970d 372 Pfam PF00905 Penicillin binding protein transpeptidase domain 57 343 1.4E-33 T 22-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 HRM2_RS13280 098939e3da6383fe4e425e63f2b9970d 372 PANTHER PTHR30627 25 336 9.2E-41 T 22-04-2016 HRM2_RS13280 098939e3da6383fe4e425e63f2b9970d 372 SUPERFAMILY SSF56601 28 364 7.17E-51 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HRM2_RS13280 098939e3da6383fe4e425e63f2b9970d 372 PANTHER PTHR30627:SF3 25 336 9.2E-41 T 22-04-2016 HRM2_RS20225 f5a285aea90715a2e7368d8b890755a5 490 SUPERFAMILY SSF48695 56 256 3.05E-26 T 22-04-2016 IPR011031 Multihaem cytochrome HRM2_RS20225 f5a285aea90715a2e7368d8b890755a5 490 Pfam PF13435 Cytochrome c554 and c-prime 61 144 6.8E-13 T 22-04-2016 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674|UniPathway: UPA00653 HRM2_RS20225 f5a285aea90715a2e7368d8b890755a5 490 Gene3D G3DSA:1.10.710.10 54 258 3.6E-19 T 22-04-2016 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674|UniPathway: UPA00653 HRM2_RS22180 f1274842b4f655e6519951e0b66d8bce 133 Pfam PF13534 4Fe-4S dicluster domain 32 103 3.1E-7 T 22-04-2016 HRM2_RS22180 f1274842b4f655e6519951e0b66d8bce 133 Gene3D G3DSA:1.10.1060.10 24 115 2.8E-10 T 22-04-2016 HRM2_RS22180 f1274842b4f655e6519951e0b66d8bce 133 SUPERFAMILY SSF46548 23 117 2.44E-8 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS04395 666575d2c1ccd96ffafe58fe2fb1e691 473 Pfam PF07690 Major Facilitator Superfamily 15 408 1.1E-51 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS04395 666575d2c1ccd96ffafe58fe2fb1e691 473 SUPERFAMILY SSF103473 247 466 1.57E-67 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS04395 666575d2c1ccd96ffafe58fe2fb1e691 473 SUPERFAMILY SSF103473 6 192 1.57E-67 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS04395 666575d2c1ccd96ffafe58fe2fb1e691 473 Gene3D G3DSA:1.20.1250.20 6 188 5.4E-30 T 22-04-2016 HRM2_RS04395 666575d2c1ccd96ffafe58fe2fb1e691 473 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 12 450 3.1E-71 T 22-04-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 HRM2_RS04395 666575d2c1ccd96ffafe58fe2fb1e691 473 Gene3D G3DSA:1.20.1250.20 260 471 9.8E-18 T 22-04-2016 HRM2_RS04395 666575d2c1ccd96ffafe58fe2fb1e691 473 PANTHER PTHR23501 6 471 9.1E-115 T 22-04-2016 HRM2_RS04395 666575d2c1ccd96ffafe58fe2fb1e691 473 PRINTS PR01036 Tetracycline resistance protein TetB signature 105 125 3.5E-8 T 22-04-2016 HRM2_RS04395 666575d2c1ccd96ffafe58fe2fb1e691 473 PRINTS PR01036 Tetracycline resistance protein TetB signature 14 38 3.5E-8 T 22-04-2016 HRM2_RS04395 666575d2c1ccd96ffafe58fe2fb1e691 473 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 159 3.5E-8 T 22-04-2016 HRM2_RS05625 28d36460b0a0bc81f63caac0e587775c 201 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 39 58 2.1E-6 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site HRM2_RS05625 28d36460b0a0bc81f63caac0e587775c 201 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 39 59 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site HRM2_RS05625 28d36460b0a0bc81f63caac0e587775c 201 Gene3D G3DSA:3.30.700.10 41 66 3.4E-4 T 22-04-2016 HRM2_RS05625 28d36460b0a0bc81f63caac0e587775c 201 SUPERFAMILY SSF54523 41 136 5.89E-10 T 22-04-2016 HRM2_RS05625 28d36460b0a0bc81f63caac0e587775c 201 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 35 58 2.7E-8 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site HRM2_RS16725 360a8e1015de74dcfb6499f52c8c4d2d 206 Pfam PF12654 Domain of unknown function (DUF3786) 17 194 2.2E-46 T 22-04-2016 IPR024264 Domain of unknown function DUF3786 HRM2_RS05245 e0512989cb7cafd0d6ff8f87906df59f 283 Gene3D G3DSA:3.40.250.10 9 109 1.0E-24 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS05245 e0512989cb7cafd0d6ff8f87906df59f 283 ProSitePatterns PS00380 Rhodanese signature 1. 41 52 - T 22-04-2016 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 HRM2_RS05245 e0512989cb7cafd0d6ff8f87906df59f 283 PANTHER PTHR33531:SF1 45 279 8.5E-14 T 22-04-2016 HRM2_RS05245 e0512989cb7cafd0d6ff8f87906df59f 283 Gene3D G3DSA:1.20.1260.10 120 275 2.3E-26 T 22-04-2016 IPR012347 Ferritin-related HRM2_RS05245 e0512989cb7cafd0d6ff8f87906df59f 283 PANTHER PTHR33531 45 279 8.5E-14 T 22-04-2016 HRM2_RS05245 e0512989cb7cafd0d6ff8f87906df59f 283 SUPERFAMILY SSF52821 4 109 2.49E-28 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS05245 e0512989cb7cafd0d6ff8f87906df59f 283 Pfam PF02915 Rubrerythrin 130 270 8.4E-11 T 22-04-2016 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 HRM2_RS05245 e0512989cb7cafd0d6ff8f87906df59f 283 Pfam PF00581 Rhodanese-like domain 16 107 1.0E-15 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS05245 e0512989cb7cafd0d6ff8f87906df59f 283 SUPERFAMILY SSF47240 127 277 5.13E-23 T 22-04-2016 IPR009078 Ferritin-like superfamily HRM2_RS05245 e0512989cb7cafd0d6ff8f87906df59f 283 SMART SM00450 16 112 4.1E-17 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS25295 ee8dbcd118db75b9abf7942b254222af 166 SUPERFAMILY SSF52821 62 165 3.8E-22 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS25295 ee8dbcd118db75b9abf7942b254222af 166 Gene3D G3DSA:3.40.250.10 63 165 1.7E-20 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS25295 ee8dbcd118db75b9abf7942b254222af 166 SMART SM00450 60 162 9.7E-13 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS25295 ee8dbcd118db75b9abf7942b254222af 166 Pfam PF00581 Rhodanese-like domain 71 157 4.4E-14 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS25295 ee8dbcd118db75b9abf7942b254222af 166 ProSitePatterns PS00380 Rhodanese signature 1. 86 97 - T 22-04-2016 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 HRM2_RS13940 ed23fffbb5bf1aa587023990e45d2b47 454 Pfam PF01769 Divalent cation transporter 320 446 4.7E-30 T 22-04-2016 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 HRM2_RS13940 ed23fffbb5bf1aa587023990e45d2b47 454 SUPERFAMILY SSF161093 278 452 6.41E-48 T 22-04-2016 HRM2_RS13940 ed23fffbb5bf1aa587023990e45d2b47 454 SUPERFAMILY SSF54631 135 269 4.51E-29 T 22-04-2016 HRM2_RS13940 ed23fffbb5bf1aa587023990e45d2b47 454 Gene3D G3DSA:1.25.60.10 7 128 1.5E-21 T 22-04-2016 HRM2_RS13940 ed23fffbb5bf1aa587023990e45d2b47 454 Gene3D G3DSA:1.10.357.20 278 453 3.3E-51 T 22-04-2016 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 HRM2_RS13940 ed23fffbb5bf1aa587023990e45d2b47 454 Gene3D G3DSA:3.10.580.10 129 259 1.7E-21 T 22-04-2016 HRM2_RS13940 ed23fffbb5bf1aa587023990e45d2b47 454 SMART SM00924 32 136 3.4E-20 T 22-04-2016 IPR006668 Magnesium transporter, MgtE intracellular domain HRM2_RS13940 ed23fffbb5bf1aa587023990e45d2b47 454 SMART SM00116 207 255 1.3E-6 T 22-04-2016 IPR000644 CBS domain HRM2_RS13940 ed23fffbb5bf1aa587023990e45d2b47 454 SMART SM00116 143 196 110.0 T 22-04-2016 IPR000644 CBS domain HRM2_RS13940 ed23fffbb5bf1aa587023990e45d2b47 454 SUPERFAMILY SSF158791 7 133 6.67E-22 T 22-04-2016 HRM2_RS13940 ed23fffbb5bf1aa587023990e45d2b47 454 Pfam PF03448 MgtE intracellular N domain 33 134 6.2E-16 T 22-04-2016 IPR006668 Magnesium transporter, MgtE intracellular domain HRM2_RS13940 ed23fffbb5bf1aa587023990e45d2b47 454 TIGRFAM TIGR00400 mgtE: magnesium transporter 5 454 6.5E-106 T 22-04-2016 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 HRM2_RS13940 ed23fffbb5bf1aa587023990e45d2b47 454 Pfam PF00571 CBS domain 201 255 1.5E-10 T 22-04-2016 IPR000644 CBS domain HRM2_RS13940 ed23fffbb5bf1aa587023990e45d2b47 454 PANTHER PTHR41394 7 454 8.3E-37 T 22-04-2016 HRM2_RS21610 5a24da12fd9a83505c01aad5d46dd6f9 195 PANTHER PTHR34478:SF2 1 195 9.6E-83 T 22-04-2016 HRM2_RS21610 5a24da12fd9a83505c01aad5d46dd6f9 195 PANTHER PTHR34478 1 195 9.6E-83 T 22-04-2016 HRM2_RS21610 5a24da12fd9a83505c01aad5d46dd6f9 195 SUPERFAMILY SSF140478 26 184 8.76E-54 T 22-04-2016 IPR023353 LemA-like domain HRM2_RS21610 5a24da12fd9a83505c01aad5d46dd6f9 195 Gene3D G3DSA:1.20.1440.20 16 194 9.9E-64 T 22-04-2016 IPR023353 LemA-like domain HRM2_RS21610 5a24da12fd9a83505c01aad5d46dd6f9 195 Pfam PF04011 LemA family 8 194 1.4E-67 T 22-04-2016 IPR007156 LemA HRM2_RS22160 26396b22f8a7da5056dd5a95fd689448 800 PANTHER PTHR33303:SF3 10 138 2.3E-83 T 22-04-2016 HRM2_RS22160 26396b22f8a7da5056dd5a95fd689448 800 PANTHER PTHR33303:SF3 292 710 2.3E-83 T 22-04-2016 HRM2_RS22160 26396b22f8a7da5056dd5a95fd689448 800 Pfam PF13380 CoA binding domain 311 426 1.1E-12 T 22-04-2016 IPR003781 CoA-binding GO:0048037 HRM2_RS22160 26396b22f8a7da5056dd5a95fd689448 800 PANTHER PTHR33303 10 138 2.3E-83 T 22-04-2016 HRM2_RS22160 26396b22f8a7da5056dd5a95fd689448 800 PANTHER PTHR33303 292 710 2.3E-83 T 22-04-2016 HRM2_RS22160 26396b22f8a7da5056dd5a95fd689448 800 Gene3D G3DSA:3.40.50.261 439 600 5.8E-14 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS22160 26396b22f8a7da5056dd5a95fd689448 800 SUPERFAMILY SSF52210 449 597 7.59E-26 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS22160 26396b22f8a7da5056dd5a95fd689448 800 Gene3D G3DSA:3.40.50.720 296 438 6.9E-24 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS22160 26396b22f8a7da5056dd5a95fd689448 800 SUPERFAMILY SSF51735 297 442 4.68E-21 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS22160 26396b22f8a7da5056dd5a95fd689448 800 Pfam PF13549 ATP-grasp domain 17 284 1.7E-21 T 22-04-2016 HRM2_RS22160 26396b22f8a7da5056dd5a95fd689448 800 SUPERFAMILY SSF52210 613 787 8.9E-15 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 HRM2_RS22160 26396b22f8a7da5056dd5a95fd689448 800 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 466 600 6.0E-35 T 22-04-2016 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain HRM2_RS22160 26396b22f8a7da5056dd5a95fd689448 800 SMART SM00881 306 402 9.5E-10 T 22-04-2016 IPR003781 CoA-binding GO:0048037 HRM2_RS22160 26396b22f8a7da5056dd5a95fd689448 800 SUPERFAMILY SSF56059 117 190 9.89E-6 T 22-04-2016 HRM2_RS22160 26396b22f8a7da5056dd5a95fd689448 800 SUPERFAMILY SSF56059 27 89 9.89E-6 T 22-04-2016 HRM2_RS23055 803e657b43cd46ebdb6a355694e993bb 444 PIRSF PIRSF006066 7 444 3.0E-91 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS23055 803e657b43cd46ebdb6a355694e993bb 444 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 13 433 1.5E-85 T 22-04-2016 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit HRM2_RS23055 803e657b43cd46ebdb6a355694e993bb 444 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 23 439 3.7E-106 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS23055 803e657b43cd46ebdb6a355694e993bb 444 PANTHER PTHR33362 1 443 5.3E-126 T 22-04-2016 HRM2_RS23055 803e657b43cd46ebdb6a355694e993bb 444 PANTHER PTHR33362:SF5 1 443 5.3E-126 T 22-04-2016 HRM2_RS15465 5f043385840bbfb237c78e1e63f50c7e 77 SUPERFAMILY SSF47336 3 76 5.1E-20 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain HRM2_RS15465 5f043385840bbfb237c78e1e63f50c7e 77 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 76 7.3E-25 T 22-04-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 HRM2_RS15465 5f043385840bbfb237c78e1e63f50c7e 77 Hamap MF_01217 Acyl carrier protein [acpP]. 2 77 18.619 T 22-04-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 HRM2_RS15465 5f043385840bbfb237c78e1e63f50c7e 77 Pfam PF00550 Phosphopantetheine attachment site 6 73 6.4E-13 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain HRM2_RS15465 5f043385840bbfb237c78e1e63f50c7e 77 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 35 75 3.0E-4 T 22-04-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 HRM2_RS15465 5f043385840bbfb237c78e1e63f50c7e 77 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 22-04-2016 IPR006162 Phosphopantetheine attachment site HRM2_RS15465 5f043385840bbfb237c78e1e63f50c7e 77 PANTHER PTHR20863 3 77 5.7E-18 T 22-04-2016 HRM2_RS15465 5f043385840bbfb237c78e1e63f50c7e 77 Gene3D G3DSA:1.10.1200.10 2 76 1.7E-25 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain HRM2_RS10380 f3aa83e03d0047f3dcaef98d41037622 530 Gene3D G3DSA:3.20.20.70 2 353 6.7E-120 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS10380 f3aa83e03d0047f3dcaef98d41037622 530 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 22-04-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 HRM2_RS10380 f3aa83e03d0047f3dcaef98d41037622 530 SUPERFAMILY SSF110921 401 516 5.75E-21 T 22-04-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 HRM2_RS10380 f3aa83e03d0047f3dcaef98d41037622 530 SUPERFAMILY SSF51569 1 298 1.83E-77 T 22-04-2016 HRM2_RS10380 f3aa83e03d0047f3dcaef98d41037622 530 PANTHER PTHR10277:SF5 2 530 1.1E-244 T 22-04-2016 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101|UniPathway: UPA00047 HRM2_RS10380 f3aa83e03d0047f3dcaef98d41037622 530 PANTHER PTHR10277 2 530 1.1E-244 T 22-04-2016 HRM2_RS10380 f3aa83e03d0047f3dcaef98d41037622 530 SMART SM00917 380 522 1.2E-36 T 22-04-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 HRM2_RS10380 f3aa83e03d0047f3dcaef98d41037622 530 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 4 528 2.7E-214 T 22-04-2016 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101|UniPathway: UPA00047 HRM2_RS10380 f3aa83e03d0047f3dcaef98d41037622 530 Pfam PF08502 LeuA allosteric (dimerisation) domain 381 520 8.4E-27 T 22-04-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 HRM2_RS10380 f3aa83e03d0047f3dcaef98d41037622 530 Pfam PF00682 HMGL-like 4 278 5.5E-42 T 22-04-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 HRM2_RS10380 f3aa83e03d0047f3dcaef98d41037622 530 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 208 221 - T 22-04-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 HRM2_RS17895 a4193fe5b3e207fb0495a99e6186f947 207 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 206 32.996 T 22-04-2016 IPR013005 50S ribosomal protein uL4 HRM2_RS17895 a4193fe5b3e207fb0495a99e6186f947 207 Gene3D G3DSA:3.40.1370.10 58 205 1.3E-58 T 22-04-2016 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 HRM2_RS17895 a4193fe5b3e207fb0495a99e6186f947 207 Pfam PF00573 Ribosomal protein L4/L1 family 19 203 9.6E-69 T 22-04-2016 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 HRM2_RS17895 a4193fe5b3e207fb0495a99e6186f947 207 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 19 202 3.6E-76 T 22-04-2016 IPR013005 50S ribosomal protein uL4 HRM2_RS17895 a4193fe5b3e207fb0495a99e6186f947 207 PANTHER PTHR10746 1 202 7.4E-88 T 22-04-2016 IPR013005 50S ribosomal protein uL4 HRM2_RS17895 a4193fe5b3e207fb0495a99e6186f947 207 SUPERFAMILY SSF52166 1 205 4.71E-75 T 22-04-2016 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 HRM2_RS25685 3bff7e2d86b9731e043eb04eac96f198 180 PANTHER PTHR15910 11 175 4.0E-21 T 22-04-2016 HRM2_RS25685 3bff7e2d86b9731e043eb04eac96f198 180 SUPERFAMILY SSF55486 69 165 2.54E-7 T 22-04-2016 HRM2_RS25685 3bff7e2d86b9731e043eb04eac96f198 180 Pfam PF07998 Peptidase family M54 75 168 1.8E-15 T 22-04-2016 IPR012962 Peptidase M54, archaemetzincin GO:0008270 HRM2_RS19190 67ff1d3232d65e579b5eb134d19621aa 361 Pfam PF00037 4Fe-4S binding domain 272 294 8.4E-5 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS19190 67ff1d3232d65e579b5eb134d19621aa 361 Pfam PF00037 4Fe-4S binding domain 300 322 9.9E-9 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS19190 67ff1d3232d65e579b5eb134d19621aa 361 Gene3D G3DSA:3.30.70.20 268 329 5.2E-17 T 22-04-2016 HRM2_RS19190 67ff1d3232d65e579b5eb134d19621aa 361 SUPERFAMILY SSF54862 271 326 3.43E-17 T 22-04-2016 HRM2_RS19190 67ff1d3232d65e579b5eb134d19621aa 361 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 306 317 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS04805 b65e5c5d731c9cfb008c5f35f8b9750a 384 Gene3D G3DSA:3.20.20.70 4 339 2.9E-101 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS04805 b65e5c5d731c9cfb008c5f35f8b9750a 384 PANTHER PTHR10277 7 379 1.5E-113 T 22-04-2016 HRM2_RS04805 b65e5c5d731c9cfb008c5f35f8b9750a 384 Pfam PF00682 HMGL-like 10 263 1.1E-73 T 22-04-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 HRM2_RS04805 b65e5c5d731c9cfb008c5f35f8b9750a 384 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 17 33 - T 22-04-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 HRM2_RS04805 b65e5c5d731c9cfb008c5f35f8b9750a 384 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 196 209 - T 22-04-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 HRM2_RS04805 b65e5c5d731c9cfb008c5f35f8b9750a 384 SUPERFAMILY SSF51569 4 285 9.34E-78 T 22-04-2016 HRM2_RS04805 b65e5c5d731c9cfb008c5f35f8b9750a 384 PANTHER PTHR10277:SF45 7 379 1.5E-113 T 22-04-2016 HRM2_RS15100 788dc31549203b097f4733f62f1afdee 236 PANTHER PTHR30625:SF3 8 234 7.2E-54 T 22-04-2016 HRM2_RS15100 788dc31549203b097f4733f62f1afdee 236 TIGRFAM TIGR02796 tolQ: protein TolQ 8 228 3.4E-71 T 22-04-2016 IPR014163 Tol-Pal system, TolQ GO:0015031|GO:0016021 HRM2_RS15100 788dc31549203b097f4733f62f1afdee 236 Pfam PF01618 MotA/TolQ/ExbB proton channel family 114 216 4.7E-39 T 22-04-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 HRM2_RS15100 788dc31549203b097f4733f62f1afdee 236 PANTHER PTHR30625 8 234 7.2E-54 T 22-04-2016 HRM2_RS08800 acfdd2cc789d3c2cd42a078c9fbfd5a2 230 Pfam PF01476 LysM domain 187 229 1.4E-11 T 22-04-2016 IPR018392 LysM domain HRM2_RS08800 acfdd2cc789d3c2cd42a078c9fbfd5a2 230 SUPERFAMILY SSF54106 185 229 6.54E-10 T 22-04-2016 IPR018392 LysM domain HRM2_RS08800 acfdd2cc789d3c2cd42a078c9fbfd5a2 230 Gene3D G3DSA:3.10.350.10 185 229 6.5E-15 T 22-04-2016 IPR018392 LysM domain HRM2_RS08800 acfdd2cc789d3c2cd42a078c9fbfd5a2 230 SMART SM00257 186 230 5.5E-14 T 22-04-2016 IPR018392 LysM domain HRM2_RS12795 d0612e489fd9a2d4985b4419806d0c4a 177 Gene3D G3DSA:3.30.530.20 24 149 7.0E-6 T 22-04-2016 IPR023393 START-like domain HRM2_RS12795 d0612e489fd9a2d4985b4419806d0c4a 177 SUPERFAMILY SSF55961 21 158 1.28E-11 T 22-04-2016 HRM2_RS25145 0c5e69f569e59414e481eae0c4332949 472 Pfam PF06782 Uncharacterised protein family (UPF0236) 89 457 2.5E-12 T 22-04-2016 IPR009620 Uncharacterised protein family UPF0236 HRM2_RS24350 a496fb5c269b4f7d3ca325920ad1caad 340 SUPERFAMILY SSF52540 10 268 2.72E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24350 a496fb5c269b4f7d3ca325920ad1caad 340 PANTHER PTHR24220 41 335 6.4E-145 T 22-04-2016 HRM2_RS24350 a496fb5c269b4f7d3ca325920ad1caad 340 PANTHER PTHR24220 9 22 6.4E-145 T 22-04-2016 HRM2_RS24350 a496fb5c269b4f7d3ca325920ad1caad 340 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS24350 a496fb5c269b4f7d3ca325920ad1caad 340 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 247 331 2.2E-28 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HRM2_RS24350 a496fb5c269b4f7d3ca325920ad1caad 340 Gene3D G3DSA:3.40.50.300 27 270 2.9E-81 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS24350 a496fb5c269b4f7d3ca325920ad1caad 340 SMART SM00382 53 246 1.1E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS24350 a496fb5c269b4f7d3ca325920ad1caad 340 Pfam PF00005 ABC transporter 44 196 3.6E-33 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS24350 a496fb5c269b4f7d3ca325920ad1caad 340 PANTHER PTHR24220:SF336 41 335 6.4E-145 T 22-04-2016 HRM2_RS24350 a496fb5c269b4f7d3ca325920ad1caad 340 PANTHER PTHR24220:SF336 9 22 6.4E-145 T 22-04-2016 HRM2_RS24350 a496fb5c269b4f7d3ca325920ad1caad 340 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 249 312 1.4E-16 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HRM2_RS01970 5638c1cb9eef95a28a6eed39688b8123 247 Gene3D G3DSA:1.10.10.200 1 78 2.5E-37 T 22-04-2016 IPR017856 Integrase, N-terminal zinc-binding domain-like HRM2_RS01970 5638c1cb9eef95a28a6eed39688b8123 247 Gene3D G3DSA:3.30.70.980 137 205 3.8E-29 T 22-04-2016 IPR026564 Transcriptional regulator TACO1-like, domain 3 HRM2_RS01970 5638c1cb9eef95a28a6eed39688b8123 247 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 239 37.675 T 22-04-2016 IPR002876 Transcriptional regulator TACO1-like HRM2_RS01970 5638c1cb9eef95a28a6eed39688b8123 247 Pfam PF01709 Transcriptional regulator 5 237 2.7E-98 T 22-04-2016 IPR002876 Transcriptional regulator TACO1-like HRM2_RS01970 5638c1cb9eef95a28a6eed39688b8123 247 Gene3D G3DSA:3.30.1270.10 82 136 2.5E-40 T 22-04-2016 IPR026563 Transcriptional regulator TACO1-like, domain 2 HRM2_RS01970 5638c1cb9eef95a28a6eed39688b8123 247 Gene3D G3DSA:3.30.1270.10 212 246 2.5E-40 T 22-04-2016 IPR026563 Transcriptional regulator TACO1-like, domain 2 HRM2_RS01970 5638c1cb9eef95a28a6eed39688b8123 247 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 237 2.7E-103 T 22-04-2016 IPR002876 Transcriptional regulator TACO1-like HRM2_RS01970 5638c1cb9eef95a28a6eed39688b8123 247 SUPERFAMILY SSF75625 3 246 2.35E-99 T 22-04-2016 IPR029072 YebC-like HRM2_RS01970 5638c1cb9eef95a28a6eed39688b8123 247 PANTHER PTHR12532 1 241 1.1E-117 T 22-04-2016 IPR002876 Transcriptional regulator TACO1-like HRM2_RS02460 cf3ee28edd0f3f90c3cb7d424c67a351 99 Pfam PF02325 YGGT family 17 87 7.7E-21 T 22-04-2016 IPR003425 CCB3/YggT GO:0016020 HRM2_RS02460 cf3ee28edd0f3f90c3cb7d424c67a351 99 PANTHER PTHR33219 1 98 1.0E-20 T 22-04-2016 HRM2_RS02460 cf3ee28edd0f3f90c3cb7d424c67a351 99 PANTHER PTHR33219:SF5 1 98 1.0E-20 T 22-04-2016 HRM2_RS03690 bd25f3d9a53890fae9a8a1326223e415 486 Pfam PF01926 50S ribosome-binding GTPase 269 388 6.3E-17 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 HRM2_RS03690 bd25f3d9a53890fae9a8a1326223e415 486 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 144 427 9.4E-102 T 22-04-2016 IPR016496 GTPase HflX GO:0005525 HRM2_RS03690 bd25f3d9a53890fae9a8a1326223e415 486 Gene3D G3DSA:3.40.50.300 264 435 5.5E-27 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03690 bd25f3d9a53890fae9a8a1326223e415 486 PANTHER PTHR10229 27 97 2.0E-114 T 22-04-2016 IPR016496 GTPase HflX GO:0005525 HRM2_RS03690 bd25f3d9a53890fae9a8a1326223e415 486 PANTHER PTHR10229 138 472 2.0E-114 T 22-04-2016 IPR016496 GTPase HflX GO:0005525 HRM2_RS03690 bd25f3d9a53890fae9a8a1326223e415 486 SUPERFAMILY SSF52540 268 438 2.17E-32 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03690 bd25f3d9a53890fae9a8a1326223e415 486 Hamap MF_00900 GTPase HflX [hflX]. 54 458 42.725 T 22-04-2016 IPR016496 GTPase HflX GO:0005525 HRM2_RS03690 bd25f3d9a53890fae9a8a1326223e415 486 Pfam PF13167 GTP-binding GTPase N-terminal 52 97 2.4E-9 T 22-04-2016 IPR025121 GTPase HflX, N-terminal HRM2_RS03690 bd25f3d9a53890fae9a8a1326223e415 486 Pfam PF13167 GTP-binding GTPase N-terminal 144 183 3.9E-11 T 22-04-2016 IPR025121 GTPase HflX, N-terminal HRM2_RS03690 bd25f3d9a53890fae9a8a1326223e415 486 PIRSF PIRSF006809 25 486 1.6E-139 T 22-04-2016 IPR016496 GTPase HflX GO:0005525 HRM2_RS03690 bd25f3d9a53890fae9a8a1326223e415 486 PANTHER PTHR10229:SF0 27 97 2.0E-114 T 22-04-2016 HRM2_RS03690 bd25f3d9a53890fae9a8a1326223e415 486 PANTHER PTHR10229:SF0 138 472 2.0E-114 T 22-04-2016 HRM2_RS03690 bd25f3d9a53890fae9a8a1326223e415 486 Pfam PF16360 GTP-binding GTPase Middle Region 186 264 1.7E-22 T 22-04-2016 IPR032305 GTP-binding protein, middle domain HRM2_RS15545 0c1094781f18ab1e15fc71324bdb549d 392 SUPERFAMILY SSF56935 299 392 5.5E-7 T 22-04-2016 HRM2_RS15545 0c1094781f18ab1e15fc71324bdb549d 392 SUPERFAMILY SSF56935 25 263 5.5E-7 T 22-04-2016 HRM2_RS15545 0c1094781f18ab1e15fc71324bdb549d 392 Gene3D G3DSA:2.40.170.10 129 284 5.5E-4 T 22-04-2016 IPR003192 Porin, LamB type GO:0006810|GO:0016020 HRM2_RS05470 2befa0dc2d510d9caabc3d1323c0d9eb 195 Gene3D G3DSA:3.40.50.10420 8 192 1.0E-37 T 22-04-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain HRM2_RS05470 2befa0dc2d510d9caabc3d1323c0d9eb 195 PANTHER PTHR23407 1 192 4.4E-34 T 22-04-2016 HRM2_RS05470 2befa0dc2d510d9caabc3d1323c0d9eb 195 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 9 187 8.8E-35 T 22-04-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase HRM2_RS05470 2befa0dc2d510d9caabc3d1323c0d9eb 195 PIRSF PIRSF006806 4 191 1.2E-34 T 22-04-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase HRM2_RS05470 2befa0dc2d510d9caabc3d1323c0d9eb 195 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 13 187 1.5E-29 T 22-04-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase HRM2_RS05470 2befa0dc2d510d9caabc3d1323c0d9eb 195 PANTHER PTHR23407:SF1 1 192 4.4E-34 T 22-04-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase HRM2_RS05470 2befa0dc2d510d9caabc3d1323c0d9eb 195 SUPERFAMILY SSF100950 16 193 6.8E-31 T 22-04-2016 HRM2_RS01695 684f88931441c56ba85feeae3aac9e36 303 SUPERFAMILY SSF144020 34 301 2.62E-43 T 22-04-2016 IPR024064 FdhE-like HRM2_RS01695 684f88931441c56ba85feeae3aac9e36 303 PANTHER PTHR37689 154 292 2.5E-17 T 22-04-2016 HRM2_RS01695 684f88931441c56ba85feeae3aac9e36 303 Gene3D G3DSA:3.90.1670.10 9 301 3.4E-64 T 22-04-2016 IPR024064 FdhE-like HRM2_RS01695 684f88931441c56ba85feeae3aac9e36 303 PANTHER PTHR37689:SF1 154 292 2.5E-17 T 22-04-2016 HRM2_RS01695 684f88931441c56ba85feeae3aac9e36 303 Pfam PF04216 Protein involved in formate dehydrogenase formation 132 300 2.1E-23 T 22-04-2016 IPR006452 Formate dehydrogenase accessory protein GO:0005737 HRM2_RS03840 7f3391324e7fa6d573bbaf8186ebaa4e 666 ProDom PD936484 POLYPROTEIN GLYCOPROTEIN M G2 TRANSMEMBRANE NONSTRUCTURAL MEMBRANE CONTAINS: PRECURSOR SIGNAL 322 664 0.005 T 22-04-2016 HRM2_RS03840 7f3391324e7fa6d573bbaf8186ebaa4e 666 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 462 663 3.8E-33 T 22-04-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HRM2_RS03840 7f3391324e7fa6d573bbaf8186ebaa4e 666 SUPERFAMILY SSF58104 350 664 5.23E-56 T 22-04-2016 HRM2_RS03840 7f3391324e7fa6d573bbaf8186ebaa4e 666 PANTHER PTHR32089 1 666 4.6E-106 T 22-04-2016 HRM2_RS03840 7f3391324e7fa6d573bbaf8186ebaa4e 666 Gene3D G3DSA:1.10.287.950 412 621 3.0E-47 T 22-04-2016 HRM2_RS03840 7f3391324e7fa6d573bbaf8186ebaa4e 666 Gene3D G3DSA:3.30.450.20 160 295 5.2E-29 T 22-04-2016 HRM2_RS03840 7f3391324e7fa6d573bbaf8186ebaa4e 666 SMART SM00283 403 664 5.3E-56 T 22-04-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HRM2_RS03840 7f3391324e7fa6d573bbaf8186ebaa4e 666 Pfam PF02743 Cache domain 38 280 1.0E-27 T 22-04-2016 IPR033479 Double Cache domain 1 HRM2_RS03840 7f3391324e7fa6d573bbaf8186ebaa4e 666 SUPERFAMILY SSF103190 75 187 1.39E-5 T 22-04-2016 IPR029151 Periplasmic sensor domain-like HRM2_RS01050 d5a7832871b4133c656c8e75680cca17 106 SUPERFAMILY SSF81296 31 104 1.86E-7 T 22-04-2016 IPR014756 Immunoglobulin E-set HRM2_RS15830 13efab90f27f77582b1f6994c95affea 426 Gene3D G3DSA:1.10.1060.10 303 421 4.0E-13 T 22-04-2016 HRM2_RS15830 13efab90f27f77582b1f6994c95affea 426 PANTHER PTHR11780 27 426 1.6E-30 T 22-04-2016 HRM2_RS15830 13efab90f27f77582b1f6994c95affea 426 SUPERFAMILY SSF142019 140 276 6.67E-7 T 22-04-2016 HRM2_RS15830 13efab90f27f77582b1f6994c95affea 426 SUPERFAMILY SSF46548 308 417 7.85E-15 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS15830 13efab90f27f77582b1f6994c95affea 426 Pfam PF13237 4Fe-4S dicluster domain 347 399 2.1E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS15830 13efab90f27f77582b1f6994c95affea 426 PANTHER PTHR11780:SF1 27 426 1.6E-30 T 22-04-2016 HRM2_RS15830 13efab90f27f77582b1f6994c95affea 426 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 349 360 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS00150 3ebdb86f9b1b8f807750174447758b0e 287 PANTHER PTHR30193 1 286 7.2E-36 T 22-04-2016 HRM2_RS00150 3ebdb86f9b1b8f807750174447758b0e 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 274 3.1E-7 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS00150 3ebdb86f9b1b8f807750174447758b0e 287 Gene3D G3DSA:1.10.3720.10 52 275 4.4E-33 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS00150 3ebdb86f9b1b8f807750174447758b0e 287 SUPERFAMILY SSF161098 43 269 2.35E-35 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS07410 50f17b145eb72f36ac2c70be872064f5 71 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 41 52 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS07410 50f17b145eb72f36ac2c70be872064f5 71 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS07410 50f17b145eb72f36ac2c70be872064f5 71 Gene3D G3DSA:3.30.70.20 8 59 7.9E-14 T 22-04-2016 HRM2_RS07410 50f17b145eb72f36ac2c70be872064f5 71 SUPERFAMILY SSF54862 8 61 6.77E-17 T 22-04-2016 HRM2_RS07410 50f17b145eb72f36ac2c70be872064f5 71 Pfam PF14697 4Fe-4S dicluster domain 7 57 3.7E-9 T 22-04-2016 HRM2_RS14750 fcc6a370de600516fd9a12db91eccea3 683 SUPERFAMILY SSF56784 12 222 1.27E-20 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS14750 fcc6a370de600516fd9a12db91eccea3 683 Gene3D G3DSA:3.40.50.1000 11 218 2.4E-19 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS23490 b3a99e2d81afc0c6eed8420961b5bfe3 427 PIRSF PIRSF006066 1 426 5.3E-144 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS23490 b3a99e2d81afc0c6eed8420961b5bfe3 427 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 16 420 1.1E-128 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS23490 b3a99e2d81afc0c6eed8420961b5bfe3 427 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 6 412 6.7E-112 T 22-04-2016 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit HRM2_RS23490 b3a99e2d81afc0c6eed8420961b5bfe3 427 PANTHER PTHR33362 1 424 5.7E-137 T 22-04-2016 HRM2_RS23490 b3a99e2d81afc0c6eed8420961b5bfe3 427 PANTHER PTHR33362:SF2 1 424 5.7E-137 T 22-04-2016 HRM2_RS02860 928ad954bd1acfb7c0fb68fa97774a9c 386 PANTHER PTHR10160 1 385 5.7E-136 T 22-04-2016 HRM2_RS02860 928ad954bd1acfb7c0fb68fa97774a9c 386 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 146 2.9E-43 T 22-04-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal HRM2_RS02860 928ad954bd1acfb7c0fb68fa97774a9c 386 SUPERFAMILY SSF52283 1 178 1.62E-45 T 22-04-2016 HRM2_RS02860 928ad954bd1acfb7c0fb68fa97774a9c 386 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 151 376 4.5E-61 T 22-04-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain HRM2_RS02860 928ad954bd1acfb7c0fb68fa97774a9c 386 SMART SM01002 156 321 1.3E-54 T 22-04-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain HRM2_RS02860 928ad954bd1acfb7c0fb68fa97774a9c 386 Gene3D G3DSA:3.40.50.1770 3 197 4.8E-62 T 22-04-2016 HRM2_RS02860 928ad954bd1acfb7c0fb68fa97774a9c 386 SMART SM01003 4 147 6.1E-59 T 22-04-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal HRM2_RS02860 928ad954bd1acfb7c0fb68fa97774a9c 386 SUPERFAMILY SSF51735 148 327 4.29E-33 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS02860 928ad954bd1acfb7c0fb68fa97774a9c 386 Gene3D G3DSA:3.40.50.1770 198 373 4.2E-27 T 22-04-2016 HRM2_RS20985 3974c1a2d9c2ccd99149f5bc9a2bf965 324 Gene3D G3DSA:1.25.10.10 214 322 1.1E-10 T 22-04-2016 IPR011989 Armadillo-like helical HRM2_RS20985 3974c1a2d9c2ccd99149f5bc9a2bf965 324 SUPERFAMILY SSF48371 221 322 1.51E-9 T 22-04-2016 IPR016024 Armadillo-type fold GO:0005488 HRM2_RS20985 3974c1a2d9c2ccd99149f5bc9a2bf965 324 Pfam PF13192 Thioredoxin domain 123 191 4.3E-10 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS20985 3974c1a2d9c2ccd99149f5bc9a2bf965 324 Gene3D G3DSA:3.40.30.10 101 190 2.3E-18 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS20985 3974c1a2d9c2ccd99149f5bc9a2bf965 324 SUPERFAMILY SSF52833 113 190 7.1E-13 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS19240 f02a80d448c1825037bcacc8060a485c 503 SUPERFAMILY SSF143243 40 160 7.06E-14 T 22-04-2016 HRM2_RS19240 f02a80d448c1825037bcacc8060a485c 503 Gene3D G3DSA:1.10.645.10 137 492 1.7E-46 T 22-04-2016 IPR029014 NiFe hydrogenase-like HRM2_RS19240 f02a80d448c1825037bcacc8060a485c 503 SUPERFAMILY SSF56762 156 502 1.83E-90 T 22-04-2016 IPR029014 NiFe hydrogenase-like HRM2_RS19240 f02a80d448c1825037bcacc8060a485c 503 PANTHER PTHR11993 105 498 6.7E-143 T 22-04-2016 HRM2_RS19240 f02a80d448c1825037bcacc8060a485c 503 PANTHER PTHR11993:SF16 105 498 6.7E-143 T 22-04-2016 HRM2_RS19240 f02a80d448c1825037bcacc8060a485c 503 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 259 424 7.8E-33 T 22-04-2016 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 HRM2_RS18500 34c6c279905e5f217da6f581ab4ee5f0 217 PANTHER PTHR11067 2 204 3.5E-77 T 22-04-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 HRM2_RS18500 34c6c279905e5f217da6f581ab4ee5f0 217 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 7 198 46.391 T 22-04-2016 IPR020922 Non-canonical purine NTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 HRM2_RS18500 34c6c279905e5f217da6f581ab4ee5f0 217 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 9 193 1.8E-56 T 22-04-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 HRM2_RS18500 34c6c279905e5f217da6f581ab4ee5f0 217 PANTHER PTHR11067:SF9 2 204 3.5E-77 T 22-04-2016 HRM2_RS18500 34c6c279905e5f217da6f581ab4ee5f0 217 Gene3D G3DSA:3.90.950.10 5 199 3.2E-73 T 22-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like HRM2_RS18500 34c6c279905e5f217da6f581ab4ee5f0 217 Pfam PF01725 Ham1 family 9 193 3.0E-54 T 22-04-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 HRM2_RS18500 34c6c279905e5f217da6f581ab4ee5f0 217 SUPERFAMILY SSF52972 7 195 4.19E-66 T 22-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like HRM2_RS06105 6cd4f3123145a25186bd4f2cd6b2a92a 74 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 62 18.898 T 22-04-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS06105 6cd4f3123145a25186bd4f2cd6b2a92a 74 Pfam PF00830 Ribosomal L28 family 3 58 1.3E-23 T 22-04-2016 IPR026569 Ribosomal protein L28/L24 GO:0003735 HRM2_RS06105 6cd4f3123145a25186bd4f2cd6b2a92a 74 SUPERFAMILY SSF143800 1 63 1.96E-26 T 22-04-2016 HRM2_RS06105 6cd4f3123145a25186bd4f2cd6b2a92a 74 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 56 2.5E-25 T 22-04-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS06105 6cd4f3123145a25186bd4f2cd6b2a92a 74 PANTHER PTHR39080:SF1 2 69 1.4E-18 T 22-04-2016 HRM2_RS06105 6cd4f3123145a25186bd4f2cd6b2a92a 74 Gene3D G3DSA:2.30.170.40 2 58 1.2E-23 T 22-04-2016 HRM2_RS06105 6cd4f3123145a25186bd4f2cd6b2a92a 74 PANTHER PTHR39080 2 69 1.4E-18 T 22-04-2016 HRM2_RS01445 9e37c2447d53862b7c9799adcfc84808 199 Pfam PF04542 Sigma-70 region 2 34 101 7.6E-10 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS01445 9e37c2447d53862b7c9799adcfc84808 199 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 56 87 - T 22-04-2016 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS01445 9e37c2447d53862b7c9799adcfc84808 199 SUPERFAMILY SSF88946 14 114 3.26E-23 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS01445 9e37c2447d53862b7c9799adcfc84808 199 Gene3D G3DSA:1.10.10.10 134 197 2.5E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS01445 9e37c2447d53862b7c9799adcfc84808 199 SUPERFAMILY SSF88659 134 195 6.32E-16 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS01445 9e37c2447d53862b7c9799adcfc84808 199 Gene3D G3DSA:1.10.1740.10 14 117 1.8E-25 T 22-04-2016 HRM2_RS01445 9e37c2447d53862b7c9799adcfc84808 199 Pfam PF08281 Sigma-70, region 4 140 191 1.5E-16 T 22-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS01445 9e37c2447d53862b7c9799adcfc84808 199 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 191 2.3E-26 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS01445 9e37c2447d53862b7c9799adcfc84808 199 PANTHER PTHR30173 6 198 8.3E-44 T 22-04-2016 HRM2_RS06675 8e160589097105cae149f2ab9d05061b 346 Pfam PF01032 FecCD transport family 23 339 9.2E-79 T 22-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 HRM2_RS06675 8e160589097105cae149f2ab9d05061b 346 PANTHER PTHR30472:SF34 12 345 1.0E-120 T 22-04-2016 HRM2_RS06675 8e160589097105cae149f2ab9d05061b 346 PANTHER PTHR30472 12 345 1.0E-120 T 22-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 HRM2_RS06675 8e160589097105cae149f2ab9d05061b 346 SUPERFAMILY SSF81345 11 339 1.57E-71 T 22-04-2016 IPR029022 ABC transporter, BtuC-like HRM2_RS06675 8e160589097105cae149f2ab9d05061b 346 Gene3D G3DSA:1.10.3470.10 13 342 6.8E-94 T 22-04-2016 IPR029022 ABC transporter, BtuC-like HRM2_RS22240 c2252bf6a66f828a90aee12806fa6386 407 SUPERFAMILY SSF109604 182 399 1.0E-34 T 22-04-2016 HRM2_RS22240 c2252bf6a66f828a90aee12806fa6386 407 PANTHER PTHR33525:SF4 2 370 3.0E-100 T 22-04-2016 HRM2_RS22240 c2252bf6a66f828a90aee12806fa6386 407 Pfam PF08668 HDOD domain 200 324 9.4E-20 T 22-04-2016 IPR013976 Metal-dependent hydrolase HDOD HRM2_RS22240 c2252bf6a66f828a90aee12806fa6386 407 Gene3D G3DSA:3.20.20.450 80 182 1.6E-12 T 22-04-2016 IPR001633 EAL domain HRM2_RS22240 c2252bf6a66f828a90aee12806fa6386 407 Pfam PF00563 EAL domain 80 191 2.4E-14 T 22-04-2016 IPR001633 EAL domain HRM2_RS22240 c2252bf6a66f828a90aee12806fa6386 407 Gene3D G3DSA:1.10.3150.10 183 345 6.4E-35 T 22-04-2016 IPR013976 Metal-dependent hydrolase HDOD HRM2_RS22240 c2252bf6a66f828a90aee12806fa6386 407 PIRSF PIRSF003180 1 405 1.8E-118 T 22-04-2016 IPR014408 Signal transduction c-di-GMP phosphodiesterase, EAL/HD-GYP domain-containing HRM2_RS22240 c2252bf6a66f828a90aee12806fa6386 407 PANTHER PTHR33525 2 370 3.0E-100 T 22-04-2016 HRM2_RS22240 c2252bf6a66f828a90aee12806fa6386 407 SUPERFAMILY SSF141868 3 194 6.15E-27 T 22-04-2016 IPR001633 EAL domain HRM2_RS07015 7c6108a7cead642620907eada91a9033 402 Pfam PF11845 Protein of unknown function (DUF3365) 11 189 1.0E-24 T 22-04-2016 IPR021796 Protein of unknown function DUF3365 HRM2_RS07015 7c6108a7cead642620907eada91a9033 402 SUPERFAMILY SSF55073 237 398 2.35E-47 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS07015 7c6108a7cead642620907eada91a9033 402 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 228 396 4.8E-51 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS07015 7c6108a7cead642620907eada91a9033 402 PANTHER PTHR10799 215 394 7.1E-28 T 22-04-2016 HRM2_RS07015 7c6108a7cead642620907eada91a9033 402 SMART SM00267 221 397 1.6E-55 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS07015 7c6108a7cead642620907eada91a9033 402 Gene3D G3DSA:3.30.70.270 234 399 9.4E-51 T 22-04-2016 HRM2_RS07015 7c6108a7cead642620907eada91a9033 402 Pfam PF00990 Diguanylate cyclase, GGDEF domain 232 393 1.5E-45 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS07015 7c6108a7cead642620907eada91a9033 402 PANTHER PTHR10799:SF750 215 394 7.1E-28 T 22-04-2016 HRM2_RS14430 a5f8ddf59bf12adb94da7708341423a6 368 SUPERFAMILY SSF55347 134 355 8.51E-76 T 22-04-2016 HRM2_RS14430 a5f8ddf59bf12adb94da7708341423a6 368 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 368 32.814 T 22-04-2016 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 HRM2_RS14430 a5f8ddf59bf12adb94da7708341423a6 368 PANTHER PTHR10174:SF116 201 368 3.5E-140 T 22-04-2016 HRM2_RS14430 a5f8ddf59bf12adb94da7708341423a6 368 PANTHER PTHR10174:SF116 103 179 3.5E-140 T 22-04-2016 HRM2_RS14430 a5f8ddf59bf12adb94da7708341423a6 368 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 144 354 1.5E-52 T 22-04-2016 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HRM2_RS14430 a5f8ddf59bf12adb94da7708341423a6 368 SMART SM00859 3 122 1.7E-28 T 22-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 HRM2_RS14430 a5f8ddf59bf12adb94da7708341423a6 368 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 122 2.8E-22 T 22-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 HRM2_RS14430 a5f8ddf59bf12adb94da7708341423a6 368 PANTHER PTHR10174 201 368 3.5E-140 T 22-04-2016 HRM2_RS14430 a5f8ddf59bf12adb94da7708341423a6 368 PANTHER PTHR10174 103 179 3.5E-140 T 22-04-2016 HRM2_RS14430 a5f8ddf59bf12adb94da7708341423a6 368 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 262 276 - T 22-04-2016 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 HRM2_RS14430 a5f8ddf59bf12adb94da7708341423a6 368 SUPERFAMILY SSF51735 1 147 3.2E-49 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS14430 a5f8ddf59bf12adb94da7708341423a6 368 Gene3D G3DSA:3.30.360.10 143 351 8.8E-73 T 22-04-2016 HRM2_RS14430 a5f8ddf59bf12adb94da7708341423a6 368 PIRSF PIRSF000148 1 368 2.4E-67 T 22-04-2016 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 HRM2_RS14430 a5f8ddf59bf12adb94da7708341423a6 368 TIGRFAM TIGR01745 asd_gamma: aspartate-semialdehyde dehydrogenase 2 367 1.1E-173 T 22-04-2016 IPR011534 Aspartate-semialdehyde dehydrogenase, gamma-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 HRM2_RS14430 a5f8ddf59bf12adb94da7708341423a6 368 Gene3D G3DSA:3.40.50.720 1 142 4.9E-58 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS02440 689e4ae5f4b3ebdc26deec1b119f8f61 315 PANTHER PTHR30482:SF10 1 315 7.0E-69 T 22-04-2016 HRM2_RS02440 689e4ae5f4b3ebdc26deec1b119f8f61 315 Pfam PF02653 Branched-chain amino acid transport system / permease component 33 293 7.0E-38 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 HRM2_RS02440 689e4ae5f4b3ebdc26deec1b119f8f61 315 PANTHER PTHR30482 1 315 7.0E-69 T 22-04-2016 HRM2_RS17870 578f4a8555ea221436fa75254deca52d 215 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 6.0E-89 T 22-04-2016 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 HRM2_RS17870 578f4a8555ea221436fa75254deca52d 215 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 3.2E-38 T 22-04-2016 HRM2_RS17870 578f4a8555ea221436fa75254deca52d 215 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 22-04-2016 IPR018280 Ribosomal protein S3, conserved site HRM2_RS17870 578f4a8555ea221436fa75254deca52d 215 Gene3D G3DSA:3.30.1140.32 108 206 1.8E-43 T 22-04-2016 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 HRM2_RS17870 578f4a8555ea221436fa75254deca52d 215 Gene3D G3DSA:3.30.300.20 17 106 6.1E-31 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta HRM2_RS17870 578f4a8555ea221436fa75254deca52d 215 SMART SM00322 59 124 2.6E-7 T 22-04-2016 IPR004087 K Homology domain GO:0003676 HRM2_RS17870 578f4a8555ea221436fa75254deca52d 215 SUPERFAMILY SSF54821 107 205 2.35E-38 T 22-04-2016 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 HRM2_RS17870 578f4a8555ea221436fa75254deca52d 215 SUPERFAMILY SSF54814 2 105 8.9E-37 T 22-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 HRM2_RS17870 578f4a8555ea221436fa75254deca52d 215 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 37.257 T 22-04-2016 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 HRM2_RS17870 578f4a8555ea221436fa75254deca52d 215 Pfam PF07650 KH domain 37 109 1.3E-15 T 22-04-2016 IPR004044 K Homology domain, type 2 GO:0003723 HRM2_RS17870 578f4a8555ea221436fa75254deca52d 215 PANTHER PTHR11760:SF19 2 207 5.0E-121 T 22-04-2016 HRM2_RS17870 578f4a8555ea221436fa75254deca52d 215 PANTHER PTHR11760 2 207 5.0E-121 T 22-04-2016 HRM2_RS11340 a1ff861b825b66204673a878a6e9b8b8 591 ProSitePatterns PS01271 Sodium:sulfate symporter family signature. 539 555 - T 22-04-2016 IPR031312 Sodium/sulphate symporter, conserved site HRM2_RS11340 a1ff861b825b66204673a878a6e9b8b8 591 PANTHER PTHR10283:SF100 352 591 2.5E-129 T 22-04-2016 HRM2_RS11340 a1ff861b825b66204673a878a6e9b8b8 591 PANTHER PTHR10283:SF100 1 217 2.5E-129 T 22-04-2016 HRM2_RS11340 a1ff861b825b66204673a878a6e9b8b8 591 SUPERFAMILY SSF116726 208 285 3.14E-8 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS11340 a1ff861b825b66204673a878a6e9b8b8 591 Pfam PF02080 TrkA-C domain 218 280 2.2E-7 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS11340 a1ff861b825b66204673a878a6e9b8b8 591 SUPERFAMILY SSF116726 309 385 3.79E-7 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS11340 a1ff861b825b66204673a878a6e9b8b8 591 Pfam PF03600 Citrate transporter 14 425 1.5E-29 T 22-04-2016 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 HRM2_RS11340 a1ff861b825b66204673a878a6e9b8b8 591 Gene3D G3DSA:3.30.70.1450 309 387 4.2E-9 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS11340 a1ff861b825b66204673a878a6e9b8b8 591 Gene3D G3DSA:3.30.70.1450 216 288 1.9E-8 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HRM2_RS11340 a1ff861b825b66204673a878a6e9b8b8 591 PANTHER PTHR10283 352 591 2.5E-129 T 22-04-2016 HRM2_RS11340 a1ff861b825b66204673a878a6e9b8b8 591 PANTHER PTHR10283 1 217 2.5E-129 T 22-04-2016 HRM2_RS05145 9350f923ea9217a2dffef16bc97ef792 227 PANTHER PTHR26402 1 227 5.2E-83 T 22-04-2016 HRM2_RS05145 9350f923ea9217a2dffef16bc97ef792 227 PANTHER PTHR26402:SF316 1 227 5.2E-83 T 22-04-2016 HRM2_RS05145 9350f923ea9217a2dffef16bc97ef792 227 Gene3D G3DSA:1.10.10.10 122 224 6.2E-28 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS05145 9350f923ea9217a2dffef16bc97ef792 227 SMART SM00448 1 112 5.4E-44 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS05145 9350f923ea9217a2dffef16bc97ef792 227 Gene3D G3DSA:3.40.50.2300 1 121 4.9E-43 T 22-04-2016 HRM2_RS05145 9350f923ea9217a2dffef16bc97ef792 227 Pfam PF00072 Response regulator receiver domain 3 113 5.0E-32 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS05145 9350f923ea9217a2dffef16bc97ef792 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 222 1.4E-20 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HRM2_RS05145 9350f923ea9217a2dffef16bc97ef792 227 SUPERFAMILY SSF52172 1 171 2.7E-44 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS05145 9350f923ea9217a2dffef16bc97ef792 227 SMART SM00862 144 223 2.1E-22 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HRM2_RS22720 916198268ba490ad64fdf3740b5602bb 210 SMART SM01018 1 84 4.0E-26 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain HRM2_RS22720 916198268ba490ad64fdf3740b5602bb 210 Gene3D G3DSA:3.40.50.280 75 210 9.6E-47 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS22720 916198268ba490ad64fdf3740b5602bb 210 Pfam PF02310 B12 binding domain 90 192 1.0E-24 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS22720 916198268ba490ad64fdf3740b5602bb 210 Pfam PF02607 B12 binding domain 6 77 9.4E-18 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain HRM2_RS22720 916198268ba490ad64fdf3740b5602bb 210 SUPERFAMILY SSF47644 2 83 1.7E-21 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain HRM2_RS22720 916198268ba490ad64fdf3740b5602bb 210 SUPERFAMILY SSF52242 69 209 4.06E-41 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS22720 916198268ba490ad64fdf3740b5602bb 210 Gene3D G3DSA:1.10.1240.10 5 74 1.8E-19 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain HRM2_RS14870 142c65863c5a84a3af90ca1c60d1f5ef 313 PANTHER PTHR35271 12 309 1.1E-20 T 22-04-2016 HRM2_RS14870 142c65863c5a84a3af90ca1c60d1f5ef 313 Gene3D G3DSA:3.40.50.2300 43 159 3.8E-5 T 22-04-2016 HRM2_RS14870 142c65863c5a84a3af90ca1c60d1f5ef 313 Gene3D G3DSA:3.40.50.2300 160 284 2.7E-19 T 22-04-2016 HRM2_RS14870 142c65863c5a84a3af90ca1c60d1f5ef 313 Pfam PF04392 ABC transporter substrate binding protein 137 309 1.9E-14 T 22-04-2016 IPR007487 ABC transporter, substrate-binding protein HRM2_RS02530 af16fccd6e1976a2c63574d407917b02 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 293 7.4E-15 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS02530 af16fccd6e1976a2c63574d407917b02 296 SUPERFAMILY SSF161098 55 283 8.5E-51 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS02530 af16fccd6e1976a2c63574d407917b02 296 Gene3D G3DSA:1.10.3720.10 61 291 1.9E-52 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS02530 af16fccd6e1976a2c63574d407917b02 296 PANTHER PTHR32243 4 293 7.1E-96 T 22-04-2016 HRM2_RS02530 af16fccd6e1976a2c63574d407917b02 296 PANTHER PTHR32243:SF13 4 293 7.1E-96 T 22-04-2016 HRM2_RS10290 730411c4d11baa398fbc858e9276c2d1 84 Gene3D G3DSA:1.10.1660.10 6 76 1.3E-15 T 22-04-2016 HRM2_RS10290 730411c4d11baa398fbc858e9276c2d1 84 SUPERFAMILY SSF46955 6 76 4.03E-14 T 22-04-2016 IPR009061 Putative DNA-binding domain HRM2_RS10290 730411c4d11baa398fbc858e9276c2d1 84 SMART SM00422 6 78 7.1E-5 T 22-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HRM2_RS10290 730411c4d11baa398fbc858e9276c2d1 84 Pfam PF13411 MerR HTH family regulatory protein 6 76 1.1E-15 T 22-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HRM2_RS16980 a211d4e5a0e1a6b67a52b1179a44926c 170 Gene3D G3DSA:2.40.50.180 59 92 1.5E-9 T 22-04-2016 HRM2_RS16980 a211d4e5a0e1a6b67a52b1179a44926c 170 SUPERFAMILY SSF50341 16 162 2.62E-38 T 22-04-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HRM2_RS16980 a211d4e5a0e1a6b67a52b1179a44926c 170 PANTHER PTHR22617 16 167 3.7E-43 T 22-04-2016 HRM2_RS16980 a211d4e5a0e1a6b67a52b1179a44926c 170 Pfam PF01584 CheW-like domain 22 160 5.2E-34 T 22-04-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HRM2_RS16980 a211d4e5a0e1a6b67a52b1179a44926c 170 SMART SM00260 17 158 2.5E-36 T 22-04-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HRM2_RS16980 a211d4e5a0e1a6b67a52b1179a44926c 170 Gene3D G3DSA:2.30.30.40 93 151 3.1E-6 T 22-04-2016 HRM2_RS15965 bbed517b2197fe1f432cbbc7d5b54a2a 441 PANTHER PTHR33171:SF3 1 318 2.6E-49 T 22-04-2016 HRM2_RS15965 bbed517b2197fe1f432cbbc7d5b54a2a 441 Pfam PF09861 Domain of unknown function (DUF2088) 8 205 1.2E-48 T 22-04-2016 IPR018657 Domain of unknown function DUF2088 HRM2_RS15965 bbed517b2197fe1f432cbbc7d5b54a2a 441 PANTHER PTHR33171 1 318 2.6E-49 T 22-04-2016 HRM2_RS15965 bbed517b2197fe1f432cbbc7d5b54a2a 441 Gene3D G3DSA:3.40.50.1220 78 172 1.1E-4 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HRM2_RS19275 eec89f167757516899a870d23d53899d 214 PANTHER PTHR31168:SF1 1 211 9.0E-52 T 22-04-2016 HRM2_RS19275 eec89f167757516899a870d23d53899d 214 Pfam PF04654 Protein of unknown function, DUF599 10 212 9.8E-62 T 22-04-2016 IPR006747 Protein of unknown function DUF599 HRM2_RS19275 eec89f167757516899a870d23d53899d 214 PANTHER PTHR31168 1 211 9.0E-52 T 22-04-2016 HRM2_RS25180 2c6acfc51ca5607cf06b894d3dec218d 221 PANTHER PTHR30055 8 142 6.6E-17 T 22-04-2016 HRM2_RS25180 2c6acfc51ca5607cf06b894d3dec218d 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 8.7E-6 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS25180 2c6acfc51ca5607cf06b894d3dec218d 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 8.7E-6 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS25180 2c6acfc51ca5607cf06b894d3dec218d 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 1.5E-11 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS25180 2c6acfc51ca5607cf06b894d3dec218d 221 SUPERFAMILY SSF46689 4 77 1.13E-16 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS25180 2c6acfc51ca5607cf06b894d3dec218d 221 Gene3D G3DSA:1.10.357.10 3 200 2.8E-28 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HRM2_RS23280 2c24265f098c5361705d56a786212071 942 SMART SM00490 805 886 5.2E-15 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS23280 2c24265f098c5361705d56a786212071 942 Gene3D G3DSA:3.40.50.300 483 652 3.1E-25 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23280 2c24265f098c5361705d56a786212071 942 Pfam PF00176 SNF2 family N-terminal domain 501 762 5.4E-56 T 22-04-2016 IPR000330 SNF2-related, N-terminal domain GO:0005524 HRM2_RS23280 2c24265f098c5361705d56a786212071 942 Pfam PF00271 Helicase conserved C-terminal domain 780 886 2.9E-12 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS23280 2c24265f098c5361705d56a786212071 942 SMART SM00487 483 666 3.2E-27 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS23280 2c24265f098c5361705d56a786212071 942 PANTHER PTHR10799 481 925 7.5E-156 T 22-04-2016 HRM2_RS23280 2c24265f098c5361705d56a786212071 942 Gene3D G3DSA:3.40.50.300 774 918 5.0E-19 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23280 2c24265f098c5361705d56a786212071 942 SUPERFAMILY SSF52540 477 694 1.27E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23280 2c24265f098c5361705d56a786212071 942 SUPERFAMILY SSF52540 696 940 5.13E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01350 9e6f25e1b7bae26a659d17aefd1e1a2d 264 SMART SM00382 30 217 2.9E-6 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS01350 9e6f25e1b7bae26a659d17aefd1e1a2d 264 PANTHER PTHR24220:SF358 134 263 2.4E-111 T 22-04-2016 HRM2_RS01350 9e6f25e1b7bae26a659d17aefd1e1a2d 264 PANTHER PTHR24220 7 118 2.4E-111 T 22-04-2016 HRM2_RS01350 9e6f25e1b7bae26a659d17aefd1e1a2d 264 Gene3D G3DSA:3.40.50.300 2 257 2.2E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01350 9e6f25e1b7bae26a659d17aefd1e1a2d 264 PANTHER PTHR24220:SF358 7 118 2.4E-111 T 22-04-2016 HRM2_RS01350 9e6f25e1b7bae26a659d17aefd1e1a2d 264 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 237 259 6.1E-12 T 22-04-2016 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal HRM2_RS01350 9e6f25e1b7bae26a659d17aefd1e1a2d 264 SUPERFAMILY SSF52540 3 260 1.96E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01350 9e6f25e1b7bae26a659d17aefd1e1a2d 264 PANTHER PTHR24220 134 263 2.4E-111 T 22-04-2016 HRM2_RS01350 9e6f25e1b7bae26a659d17aefd1e1a2d 264 Pfam PF00005 ABC transporter 22 187 5.2E-27 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS10735 8c9f2c4c6f5e5b11f3ee9c9171ef0d3d 572 PANTHER PTHR30255:SF2 1 570 7.1E-200 T 22-04-2016 HRM2_RS10735 8c9f2c4c6f5e5b11f3ee9c9171ef0d3d 572 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 26 570 8.5E-173 T 22-04-2016 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 HRM2_RS10735 8c9f2c4c6f5e5b11f3ee9c9171ef0d3d 572 SUPERFAMILY SSF64182 56 458 4.19E-109 T 22-04-2016 HRM2_RS10735 8c9f2c4c6f5e5b11f3ee9c9171ef0d3d 572 PANTHER PTHR30255 1 570 7.1E-200 T 22-04-2016 HRM2_RS10735 8c9f2c4c6f5e5b11f3ee9c9171ef0d3d 572 Pfam PF02272 DHHA1 domain 386 442 1.4E-8 T 22-04-2016 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7 HRM2_RS10735 8c9f2c4c6f5e5b11f3ee9c9171ef0d3d 572 Pfam PF01368 DHH family 81 189 2.1E-10 T 22-04-2016 IPR001667 DDH domain HRM2_RS02380 47c5a5eae60d5ae21f81054627fb6b75 301 Gene3D G3DSA:1.10.10.10 4 55 2.4E-6 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS02380 47c5a5eae60d5ae21f81054627fb6b75 301 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 4 52 1.1E-11 T 22-04-2016 IPR010093 SinI-like, DNA-binding domain GO:0003677 HRM2_RS02380 47c5a5eae60d5ae21f81054627fb6b75 301 PANTHER PTHR38431 3 301 8.5E-45 T 22-04-2016 HRM2_RS02380 47c5a5eae60d5ae21f81054627fb6b75 301 Pfam PF12728 Helix-turn-helix domain 4 53 1.4E-11 T 22-04-2016 HRM2_RS02380 47c5a5eae60d5ae21f81054627fb6b75 301 SUPERFAMILY SSF53850 82 289 4.84E-11 T 22-04-2016 HRM2_RS02380 47c5a5eae60d5ae21f81054627fb6b75 301 Gene3D G3DSA:3.40.190.10 153 219 1.5E-8 T 22-04-2016 HRM2_RS02380 47c5a5eae60d5ae21f81054627fb6b75 301 Pfam PF12727 PBP superfamily domain 87 274 2.3E-62 T 22-04-2016 IPR024370 PBP domain HRM2_RS23415 211515000021ceb3fb61f2e349e777c2 270 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS23415 211515000021ceb3fb61f2e349e777c2 270 Gene3D G3DSA:3.40.50.300 2 223 1.1E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23415 211515000021ceb3fb61f2e349e777c2 270 PANTHER PTHR24220:SF456 4 239 2.9E-101 T 22-04-2016 HRM2_RS23415 211515000021ceb3fb61f2e349e777c2 270 SUPERFAMILY SSF52540 2 224 4.84E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23415 211515000021ceb3fb61f2e349e777c2 270 SMART SM00382 27 213 8.4E-14 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS23415 211515000021ceb3fb61f2e349e777c2 270 Pfam PF00005 ABC transporter 18 164 2.4E-32 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS23415 211515000021ceb3fb61f2e349e777c2 270 PANTHER PTHR24220 4 239 2.9E-101 T 22-04-2016 HRM2_RS12320 7d58cbe239bf74ba6a0a65bcd77ac99d 300 Gene3D G3DSA:3.90.226.10 31 146 1.1E-54 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS12320 7d58cbe239bf74ba6a0a65bcd77ac99d 300 Gene3D G3DSA:3.90.226.10 184 261 1.1E-54 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS12320 7d58cbe239bf74ba6a0a65bcd77ac99d 300 Pfam PF01343 Peptidase family S49 107 257 2.1E-50 T 22-04-2016 IPR002142 Peptidase S49 GO:0006508|GO:0008233 HRM2_RS12320 7d58cbe239bf74ba6a0a65bcd77ac99d 300 PANTHER PTHR33209 44 258 2.8E-75 T 22-04-2016 HRM2_RS12320 7d58cbe239bf74ba6a0a65bcd77ac99d 300 SUPERFAMILY SSF52096 183 244 2.89E-40 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS12320 7d58cbe239bf74ba6a0a65bcd77ac99d 300 SUPERFAMILY SSF52096 43 154 2.89E-40 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS12320 7d58cbe239bf74ba6a0a65bcd77ac99d 300 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 52 255 4.3E-73 T 22-04-2016 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 HRM2_RS25010 1c414e99965b3381be0d5b7768405a84 237 Gene3D G3DSA:3.30.70.20 120 156 2.4E-10 T 22-04-2016 HRM2_RS25010 1c414e99965b3381be0d5b7768405a84 237 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 17 44 3.1E-4 T 22-04-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal HRM2_RS25010 1c414e99965b3381be0d5b7768405a84 237 Gene3D G3DSA:3.30.70.20 157 189 2.9E-4 T 22-04-2016 HRM2_RS25010 1c414e99965b3381be0d5b7768405a84 237 Gene3D G3DSA:3.30.70.20 65 119 3.5E-8 T 22-04-2016 HRM2_RS25010 1c414e99965b3381be0d5b7768405a84 237 PANTHER PTHR11938 64 189 7.7E-16 T 22-04-2016 HRM2_RS25010 1c414e99965b3381be0d5b7768405a84 237 SUPERFAMILY SSF54862 68 190 1.42E-27 T 22-04-2016 HRM2_RS25010 1c414e99965b3381be0d5b7768405a84 237 Pfam PF13247 4Fe-4S dicluster domain 104 189 1.8E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS25010 1c414e99965b3381be0d5b7768405a84 237 PANTHER PTHR11938:SF82 64 189 7.7E-16 T 22-04-2016 HRM2_RS01080 ba066c6be3d3ff8961b0e9ac0d26ebf0 176 SUPERFAMILY SSF52540 2 171 2.57E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01080 ba066c6be3d3ff8961b0e9ac0d26ebf0 176 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 3 170 1.9E-57 T 22-04-2016 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00148|UniPathway: UPA00148 HRM2_RS01080 ba066c6be3d3ff8961b0e9ac0d26ebf0 176 PIRSF PIRSF006135 1 173 5.5E-53 T 22-04-2016 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00148|UniPathway: UPA00148 HRM2_RS01080 ba066c6be3d3ff8961b0e9ac0d26ebf0 176 Gene3D G3DSA:3.40.50.300 2 171 3.9E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01080 ba066c6be3d3ff8961b0e9ac0d26ebf0 176 PANTHER PTHR34848 1 173 1.6E-65 T 22-04-2016 HRM2_RS08205 13e15e6be13cb7bd00c345c06c0bb89f 122 PANTHER PTHR11780:SF0 28 113 2.1E-18 T 22-04-2016 HRM2_RS08205 13e15e6be13cb7bd00c345c06c0bb89f 122 Gene3D G3DSA:3.40.30.10 30 120 1.2E-15 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS08205 13e15e6be13cb7bd00c345c06c0bb89f 122 SUPERFAMILY SSF52833 31 119 9.95E-12 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS08205 13e15e6be13cb7bd00c345c06c0bb89f 122 PANTHER PTHR11780 28 113 2.1E-18 T 22-04-2016 HRM2_RS22485 4aa44eb1a58d09afaa6c0af1746ff29a 430 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 8 416 1.3E-98 T 22-04-2016 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit HRM2_RS22485 4aa44eb1a58d09afaa6c0af1746ff29a 430 PANTHER PTHR33362:SF2 1 421 9.1E-112 T 22-04-2016 HRM2_RS22485 4aa44eb1a58d09afaa6c0af1746ff29a 430 PIRSF PIRSF006066 1 426 4.0E-128 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS22485 4aa44eb1a58d09afaa6c0af1746ff29a 430 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 421 4.2E-116 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS22485 4aa44eb1a58d09afaa6c0af1746ff29a 430 PANTHER PTHR33362 1 421 9.1E-112 T 22-04-2016 HRM2_RS18055 0daa8b25fe80692d77ad8fa1022557d5 816 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 472 2.5E-156 T 22-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS18055 0daa8b25fe80692d77ad8fa1022557d5 816 SUPERFAMILY SSF101904 499 815 1.05E-106 T 22-04-2016 HRM2_RS18055 0daa8b25fe80692d77ad8fa1022557d5 816 Gene3D G3DSA:3.30.1360.40 236 332 1.2E-34 T 22-04-2016 IPR024946 Arginine repressor C-terminal-like domain HRM2_RS18055 0daa8b25fe80692d77ad8fa1022557d5 816 Gene3D G3DSA:3.90.199.10 334 399 1.7E-118 T 22-04-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 HRM2_RS18055 0daa8b25fe80692d77ad8fa1022557d5 816 Gene3D G3DSA:3.90.199.10 31 235 1.7E-118 T 22-04-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 HRM2_RS18055 0daa8b25fe80692d77ad8fa1022557d5 816 SUPERFAMILY SSF56719 31 488 8.89E-174 T 22-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 HRM2_RS18055 0daa8b25fe80692d77ad8fa1022557d5 816 SMART SM00434 11 465 5.6E-270 T 22-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 HRM2_RS18055 0daa8b25fe80692d77ad8fa1022557d5 816 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 3 809 28.706 T 22-04-2016 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HRM2_RS18055 0daa8b25fe80692d77ad8fa1022557d5 816 Gene3D G3DSA:2.120.10.90 497 805 4.0E-124 T 22-04-2016 HRM2_RS18055 0daa8b25fe80692d77ad8fa1022557d5 816 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 709 755 3.6E-12 T 22-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HRM2_RS18055 0daa8b25fe80692d77ad8fa1022557d5 816 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 611 654 5.8E-8 T 22-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HRM2_RS18055 0daa8b25fe80692d77ad8fa1022557d5 816 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 759 805 1.6E-13 T 22-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HRM2_RS18055 0daa8b25fe80692d77ad8fa1022557d5 816 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 556 604 7.9E-7 T 22-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HRM2_RS18055 0daa8b25fe80692d77ad8fa1022557d5 816 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 659 705 3.3E-10 T 22-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HRM2_RS18055 0daa8b25fe80692d77ad8fa1022557d5 816 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 504 550 1.9E-10 T 22-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HRM2_RS18055 0daa8b25fe80692d77ad8fa1022557d5 816 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 10 804 0.0 T 22-04-2016 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HRM2_RS18055 0daa8b25fe80692d77ad8fa1022557d5 816 PANTHER PTHR10169 3 775 0.0 T 22-04-2016 HRM2_RS18055 0daa8b25fe80692d77ad8fa1022557d5 816 PANTHER PTHR10169:SF48 3 775 0.0 T 22-04-2016 HRM2_RS04530 b8f662fbb9a56f45565101edf65120ae 119 Pfam PF02391 MoaE protein 10 110 3.7E-7 T 22-04-2016 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|UniPathway: UPA00344 HRM2_RS04530 b8f662fbb9a56f45565101edf65120ae 119 SUPERFAMILY SSF54690 7 111 3.14E-8 T 22-04-2016 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|UniPathway: UPA00344 HRM2_RS04530 b8f662fbb9a56f45565101edf65120ae 119 Gene3D G3DSA:3.90.1170.40 2 111 4.6E-9 T 22-04-2016 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|UniPathway: UPA00344 HRM2_RS20295 fdd5b3cfcb5f5d745c3e95e45b5ff693 187 Pfam PF01592 NifU-like N terminal domain 3 124 3.2E-49 T 22-04-2016 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 HRM2_RS20295 fdd5b3cfcb5f5d745c3e95e45b5ff693 187 PANTHER PTHR10093:SF1 1 171 5.1E-65 T 22-04-2016 HRM2_RS20295 fdd5b3cfcb5f5d745c3e95e45b5ff693 187 Pfam PF04324 BFD-like [2Fe-2S] binding domain 132 182 1.5E-16 T 22-04-2016 IPR007419 BFD-like [2Fe-2S]-binding domain HRM2_RS20295 fdd5b3cfcb5f5d745c3e95e45b5ff693 187 Gene3D G3DSA:3.90.1010.10 3 124 1.5E-41 T 22-04-2016 HRM2_RS20295 fdd5b3cfcb5f5d745c3e95e45b5ff693 187 TIGRFAM TIGR02000 NifU_proper: Fe-S cluster assembly protein NifU 1 186 8.5E-85 T 22-04-2016 IPR010238 NIF system FeS cluster assembly, NifU GO:0005506|GO:0016226|GO:0051536 HRM2_RS20295 fdd5b3cfcb5f5d745c3e95e45b5ff693 187 PANTHER PTHR10093 1 171 5.1E-65 T 22-04-2016 HRM2_RS20295 fdd5b3cfcb5f5d745c3e95e45b5ff693 187 SUPERFAMILY SSF82649 2 128 1.96E-43 T 22-04-2016 HRM2_RS15015 629155c7e690f418fa1716ec9035df0f 149 Gene3D G3DSA:3.40.1550.10 1 149 6.4E-30 T 22-04-2016 IPR028976 CheC-like domain HRM2_RS15015 629155c7e690f418fa1716ec9035df0f 149 SUPERFAMILY SSF103039 1 149 7.72E-27 T 22-04-2016 IPR028976 CheC-like domain HRM2_RS15015 629155c7e690f418fa1716ec9035df0f 149 PANTHER PTHR39452 1 149 3.6E-27 T 22-04-2016 HRM2_RS15015 629155c7e690f418fa1716ec9035df0f 149 PANTHER PTHR39452:SF1 1 149 3.6E-27 T 22-04-2016 HRM2_RS15015 629155c7e690f418fa1716ec9035df0f 149 Pfam PF13690 Chemotaxis phosphatase CheX 43 135 2.4E-16 T 22-04-2016 IPR028051 Chemotaxis phosphatase CheX-like domain KEGG: 00231+3.-.-.-|KEGG: 00563+3.-.-.-|KEGG: 00983+3.-.-.- HRM2_RS04930 7f99dfc8b3d4350385f3579ae8c7e896 556 Pfam PF13193 AMP-binding enzyme C-terminal domain 459 534 2.2E-17 T 22-04-2016 IPR025110 AMP-binding enzyme C-terminal domain HRM2_RS04930 7f99dfc8b3d4350385f3579ae8c7e896 556 Gene3D G3DSA:3.40.50.980 215 359 2.6E-44 T 22-04-2016 HRM2_RS04930 7f99dfc8b3d4350385f3579ae8c7e896 556 PANTHER PTHR24095 12 548 2.6E-188 T 22-04-2016 HRM2_RS04930 7f99dfc8b3d4350385f3579ae8c7e896 556 Gene3D G3DSA:3.40.50.980 12 214 2.4E-32 T 22-04-2016 HRM2_RS04930 7f99dfc8b3d4350385f3579ae8c7e896 556 Gene3D G3DSA:2.30.38.10 367 441 9.2E-29 T 22-04-2016 HRM2_RS04930 7f99dfc8b3d4350385f3579ae8c7e896 556 Gene3D G3DSA:3.30.300.30 447 549 4.5E-35 T 22-04-2016 HRM2_RS04930 7f99dfc8b3d4350385f3579ae8c7e896 556 SUPERFAMILY SSF56801 11 545 1.31E-145 T 22-04-2016 HRM2_RS04930 7f99dfc8b3d4350385f3579ae8c7e896 556 ProSitePatterns PS00455 Putative AMP-binding domain signature. 200 211 - T 22-04-2016 IPR020845 AMP-binding, conserved site HRM2_RS04930 7f99dfc8b3d4350385f3579ae8c7e896 556 Pfam PF00501 AMP-binding enzyme 36 450 3.6E-103 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS06860 37da21c6e6f4431c1e799a21b1545fc9 325 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 1 312 2.7E-96 T 22-04-2016 IPR007296 Domain of unknown function DUF403 HRM2_RS06860 37da21c6e6f4431c1e799a21b1545fc9 325 PANTHER PTHR34595 1 325 6.3E-121 T 22-04-2016 HRM2_RS04610 0ab2a9e727e3c5ce73396051c2766526 558 Pfam PF14104 Domain of unknown function (DUF4277) 11 111 8.4E-22 T 22-04-2016 IPR025457 Domain of unknown function DUF4277 HRM2_RS04610 0ab2a9e727e3c5ce73396051c2766526 558 PANTHER PTHR34614 1 558 5.9E-75 T 22-04-2016 HRM2_RS10775 0ab2a9e727e3c5ce73396051c2766526 558 Pfam PF14104 Domain of unknown function (DUF4277) 11 111 8.4E-22 T 22-04-2016 IPR025457 Domain of unknown function DUF4277 HRM2_RS10775 0ab2a9e727e3c5ce73396051c2766526 558 PANTHER PTHR34614 1 558 5.9E-75 T 22-04-2016 HRM2_RS11985 c24431a6f89ac9d1db3486f5fdf3d1a6 234 Pfam PF00027 Cyclic nucleotide-binding domain 44 131 3.2E-16 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain HRM2_RS11985 c24431a6f89ac9d1db3486f5fdf3d1a6 234 PANTHER PTHR24567 25 228 2.4E-42 T 22-04-2016 HRM2_RS11985 c24431a6f89ac9d1db3486f5fdf3d1a6 234 SUPERFAMILY SSF46785 160 232 1.21E-14 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS11985 c24431a6f89ac9d1db3486f5fdf3d1a6 234 Gene3D G3DSA:2.60.120.10 23 157 8.0E-32 T 22-04-2016 IPR014710 RmlC-like jelly roll fold HRM2_RS11985 c24431a6f89ac9d1db3486f5fdf3d1a6 234 SMART SM00419 182 230 2.8E-7 T 22-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HRM2_RS11985 c24431a6f89ac9d1db3486f5fdf3d1a6 234 SUPERFAMILY SSF51206 20 156 5.89E-34 T 22-04-2016 IPR018490 Cyclic nucleotide-binding-like HRM2_RS11985 c24431a6f89ac9d1db3486f5fdf3d1a6 234 Pfam PF13545 Crp-like helix-turn-helix domain 164 229 7.4E-10 T 22-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HRM2_RS11985 c24431a6f89ac9d1db3486f5fdf3d1a6 234 Gene3D G3DSA:1.10.10.10 160 231 4.7E-17 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS11985 c24431a6f89ac9d1db3486f5fdf3d1a6 234 SMART SM00100 25 143 4.6E-18 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain HRM2_RS06905 7966c50bafaa740aac35d7a354282ce5 277 Pfam PF00581 Rhodanese-like domain 170 273 1.3E-14 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS06905 7966c50bafaa740aac35d7a354282ce5 277 Pfam PF00581 Rhodanese-like domain 29 139 2.9E-14 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS06905 7966c50bafaa740aac35d7a354282ce5 277 PANTHER PTHR11364 32 272 3.4E-44 T 22-04-2016 HRM2_RS06905 7966c50bafaa740aac35d7a354282ce5 277 Gene3D G3DSA:3.40.250.10 31 150 2.3E-23 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS06905 7966c50bafaa740aac35d7a354282ce5 277 Gene3D G3DSA:3.40.250.10 163 273 1.6E-23 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS06905 7966c50bafaa740aac35d7a354282ce5 277 SMART SM00450 24 143 8.2E-12 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS06905 7966c50bafaa740aac35d7a354282ce5 277 SMART SM00450 167 277 6.0E-12 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS06905 7966c50bafaa740aac35d7a354282ce5 277 SUPERFAMILY SSF52821 31 162 2.23E-21 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS06905 7966c50bafaa740aac35d7a354282ce5 277 PANTHER PTHR11364:SF0 32 272 3.4E-44 T 22-04-2016 HRM2_RS06905 7966c50bafaa740aac35d7a354282ce5 277 SUPERFAMILY SSF52821 160 272 1.7E-25 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS08170 eec5cc4f7b317b626797a752e4aae7e4 199 SMART SM00493 81 166 8.0E-14 T 22-04-2016 IPR006171 Toprim domain HRM2_RS08170 eec5cc4f7b317b626797a752e4aae7e4 199 Hamap MF_00017 Recombination protein RecR [recR]. 1 199 92.993 T 22-04-2016 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 HRM2_RS08170 eec5cc4f7b317b626797a752e4aae7e4 199 TIGRFAM TIGR00615 recR: recombination protein RecR 4 197 9.1E-76 T 22-04-2016 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 HRM2_RS08170 eec5cc4f7b317b626797a752e4aae7e4 199 ProSitePatterns PS01300 RecR protein signature. 58 79 - T 22-04-2016 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 HRM2_RS08170 eec5cc4f7b317b626797a752e4aae7e4 199 PANTHER PTHR30446:SF0 2 199 1.1E-97 T 22-04-2016 HRM2_RS08170 eec5cc4f7b317b626797a752e4aae7e4 199 Pfam PF13662 Toprim domain 81 172 5.5E-24 T 22-04-2016 IPR006171 Toprim domain HRM2_RS08170 eec5cc4f7b317b626797a752e4aae7e4 199 Pfam PF02132 RecR protein 40 79 1.8E-13 T 22-04-2016 IPR023628 Recombination protein RecR, C4-type zinc finger HRM2_RS08170 eec5cc4f7b317b626797a752e4aae7e4 199 PANTHER PTHR30446 2 199 1.1E-97 T 22-04-2016 HRM2_RS08170 eec5cc4f7b317b626797a752e4aae7e4 199 SUPERFAMILY SSF111304 4 199 1.29E-69 T 22-04-2016 IPR023627 Recombination protein RecR HRM2_RS01185 a20fa2fd9e10031fa0f0fafc47e1a273 217 Gene3D G3DSA:1.20.58.220 4 105 1.5E-29 T 22-04-2016 HRM2_RS01185 a20fa2fd9e10031fa0f0fafc47e1a273 217 PANTHER PTHR10010 1 215 4.0E-57 T 22-04-2016 HRM2_RS01185 a20fa2fd9e10031fa0f0fafc47e1a273 217 PIRSF PIRSF003107 1 217 2.1E-61 T 22-04-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 HRM2_RS01185 a20fa2fd9e10031fa0f0fafc47e1a273 217 Gene3D G3DSA:1.20.58.220 120 215 6.4E-26 T 22-04-2016 HRM2_RS01185 a20fa2fd9e10031fa0f0fafc47e1a273 217 PANTHER PTHR10010:SF14 1 215 4.0E-57 T 22-04-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 HRM2_RS01185 a20fa2fd9e10031fa0f0fafc47e1a273 217 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 5 213 3.1E-58 T 22-04-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 HRM2_RS01185 a20fa2fd9e10031fa0f0fafc47e1a273 217 SUPERFAMILY SSF109755 5 215 5.86E-62 T 22-04-2016 HRM2_RS01185 a20fa2fd9e10031fa0f0fafc47e1a273 217 Pfam PF01895 PhoU domain 122 203 1.3E-18 T 22-04-2016 IPR026022 PhoU domain HRM2_RS01185 a20fa2fd9e10031fa0f0fafc47e1a273 217 Pfam PF01895 PhoU domain 17 104 2.7E-21 T 22-04-2016 IPR026022 PhoU domain HRM2_RS06435 9f94818a1617a90864ca42b291461d4d 849 SUPERFAMILY SSF55729 638 820 5.65E-16 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS06435 9f94818a1617a90864ca42b291461d4d 849 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 536 822 1.6E-90 T 22-04-2016 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal HRM2_RS06435 9f94818a1617a90864ca42b291461d4d 849 PANTHER PTHR34697 1 839 2.5E-233 T 22-04-2016 HRM2_RS06435 9f94818a1617a90864ca42b291461d4d 849 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 12 293 1.9E-11 T 22-04-2016 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD HRM2_RS06435 9f94818a1617a90864ca42b291461d4d 849 PANTHER PTHR34697:SF2 1 839 2.5E-233 T 22-04-2016 HRM2_RS03800 dca4150440a7e97f6d2e15a836ed8579 292 Pfam PF02754 Cysteine-rich domain 3 83 4.5E-10 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS03800 dca4150440a7e97f6d2e15a836ed8579 292 Pfam PF02754 Cysteine-rich domain 154 241 3.1E-12 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS03800 dca4150440a7e97f6d2e15a836ed8579 292 PANTHER PTHR32479 1 282 5.5E-26 T 22-04-2016 HRM2_RS03800 dca4150440a7e97f6d2e15a836ed8579 292 PANTHER PTHR32479:SF12 1 282 5.5E-26 T 22-04-2016 HRM2_RS02115 1520a345ceb4eeed9644bae307342c6f 272 Gene3D G3DSA:3.40.1190.20 6 264 1.0E-108 T 22-04-2016 IPR029056 Ribokinase-like HRM2_RS02115 1520a345ceb4eeed9644bae307342c6f 272 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 7 264 2.6E-106 T 22-04-2016 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HRM2_RS02115 1520a345ceb4eeed9644bae307342c6f 272 SUPERFAMILY SSF53613 6 269 1.56E-85 T 22-04-2016 IPR029056 Ribokinase-like HRM2_RS02115 1520a345ceb4eeed9644bae307342c6f 272 PANTHER PTHR20858 6 269 5.7E-131 T 22-04-2016 HRM2_RS02115 1520a345ceb4eeed9644bae307342c6f 272 Pfam PF08543 Phosphomethylpyrimidine kinase 14 262 2.2E-100 T 22-04-2016 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase UniPathway: UPA00647 HRM2_RS02115 1520a345ceb4eeed9644bae307342c6f 272 PANTHER PTHR20858:SF17 6 269 5.7E-131 T 22-04-2016 HRM2_RS03095 ef04f64733315c4bdac86f41433f58bd 319 SUPERFAMILY SSF56112 67 241 2.67E-9 T 22-04-2016 IPR011009 Protein kinase-like domain HRM2_RS01935 b477ab27ca4598e888ee759aea4ff0c3 162 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 139 1.2E-26 T 22-04-2016 IPR000944 Transcription regulator Rrf2-type HRM2_RS01935 b477ab27ca4598e888ee759aea4ff0c3 162 PANTHER PTHR33221 2 162 7.8E-38 T 22-04-2016 HRM2_RS01935 b477ab27ca4598e888ee759aea4ff0c3 162 Gene3D G3DSA:1.10.10.10 1 148 4.0E-34 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS01935 b477ab27ca4598e888ee759aea4ff0c3 162 PANTHER PTHR33221:SF8 2 162 7.8E-38 T 22-04-2016 HRM2_RS01935 b477ab27ca4598e888ee759aea4ff0c3 162 SUPERFAMILY SSF46785 4 144 6.48E-27 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS01935 b477ab27ca4598e888ee759aea4ff0c3 162 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 22-04-2016 IPR030489 Transcription regulator Rrf2-type, conserved site HRM2_RS01935 b477ab27ca4598e888ee759aea4ff0c3 162 Pfam PF02082 Transcriptional regulator 1 83 1.9E-23 T 22-04-2016 IPR000944 Transcription regulator Rrf2-type HRM2_RS16025 69e333f1c154e4cdb182024c9ba9d6d1 707 Gene3D G3DSA:3.40.50.280 549 703 6.9E-65 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS16025 69e333f1c154e4cdb182024c9ba9d6d1 707 PANTHER PTHR23408 1 686 0.0 T 22-04-2016 HRM2_RS16025 69e333f1c154e4cdb182024c9ba9d6d1 707 SUPERFAMILY SSF52242 547 704 1.96E-54 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS16025 69e333f1c154e4cdb182024c9ba9d6d1 707 Pfam PF02310 B12 binding domain 582 692 6.8E-16 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS16025 69e333f1c154e4cdb182024c9ba9d6d1 707 SUPERFAMILY SSF51703 6 542 8.89E-221 T 22-04-2016 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 HRM2_RS16025 69e333f1c154e4cdb182024c9ba9d6d1 707 Gene3D G3DSA:3.20.20.240 29 493 7.5E-207 T 22-04-2016 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 HRM2_RS16025 69e333f1c154e4cdb182024c9ba9d6d1 707 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 579 703 5.7E-58 T 22-04-2016 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 HRM2_RS16025 69e333f1c154e4cdb182024c9ba9d6d1 707 PANTHER PTHR23408:SF1 1 686 0.0 T 22-04-2016 HRM2_RS16025 69e333f1c154e4cdb182024c9ba9d6d1 707 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 30 547 7.9E-268 T 22-04-2016 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 HRM2_RS16025 69e333f1c154e4cdb182024c9ba9d6d1 707 Pfam PF01642 Methylmalonyl-CoA mutase 30 540 3.1E-238 T 22-04-2016 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 HRM2_RS20045 c6cbbfaad0fd6f06995eb942b85a33ec 244 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 6 236 53.964 T 22-04-2016 IPR005224 Sugar fermentation stimulation protein HRM2_RS20045 c6cbbfaad0fd6f06995eb942b85a33ec 244 PANTHER PTHR30545:SF2 6 238 6.3E-82 T 22-04-2016 HRM2_RS20045 c6cbbfaad0fd6f06995eb942b85a33ec 244 Pfam PF03749 Sugar fermentation stimulation protein 17 227 6.6E-77 T 22-04-2016 IPR005224 Sugar fermentation stimulation protein HRM2_RS20045 c6cbbfaad0fd6f06995eb942b85a33ec 244 PANTHER PTHR30545 6 238 6.3E-82 T 22-04-2016 HRM2_RS20045 c6cbbfaad0fd6f06995eb942b85a33ec 244 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 6 231 2.2E-74 T 22-04-2016 IPR005224 Sugar fermentation stimulation protein HRM2_RS14455 82c25d8cec3132167c178f2401e5fdda 687 Pfam PF06798 PrkA serine protein kinase C-terminal domain 410 679 2.9E-44 T 22-04-2016 IPR010650 PrkA C-terminal domain HRM2_RS14455 82c25d8cec3132167c178f2401e5fdda 687 Pfam PF08298 PrkA AAA domain 232 406 7.9E-7 T 22-04-2016 IPR013153 PrkA AAA domain HRM2_RS14455 82c25d8cec3132167c178f2401e5fdda 687 SMART SM00763 8 408 5.0E-109 T 22-04-2016 IPR013153 PrkA AAA domain HRM2_RS14455 82c25d8cec3132167c178f2401e5fdda 687 SUPERFAMILY SSF52540 68 136 3.61E-9 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14455 82c25d8cec3132167c178f2401e5fdda 687 SUPERFAMILY SSF52540 250 354 3.61E-9 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14455 82c25d8cec3132167c178f2401e5fdda 687 PANTHER PTHR30267:SF2 3 687 2.8E-189 T 22-04-2016 HRM2_RS14455 82c25d8cec3132167c178f2401e5fdda 687 PANTHER PTHR30267 3 687 2.8E-189 T 22-04-2016 HRM2_RS14455 82c25d8cec3132167c178f2401e5fdda 687 Gene3D G3DSA:3.40.50.300 262 361 2.6E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14455 82c25d8cec3132167c178f2401e5fdda 687 Gene3D G3DSA:3.40.50.300 91 113 2.6E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14455 82c25d8cec3132167c178f2401e5fdda 687 Gene3D G3DSA:3.40.50.300 170 189 2.6E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10540 07339391c38231888ef5fcf00b186269 334 Pfam PF02653 Branched-chain amino acid transport system / permease component 41 305 3.4E-35 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 HRM2_RS10540 07339391c38231888ef5fcf00b186269 334 PANTHER PTHR30482 6 334 1.1E-83 T 22-04-2016 HRM2_RS10540 07339391c38231888ef5fcf00b186269 334 PANTHER PTHR30482:SF1 6 334 1.1E-83 T 22-04-2016 HRM2_RS10495 7786d52ab4c9e76de564fbe6c038438f 830 Pfam PF02415 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat 294 311 0.079 T 22-04-2016 IPR003368 Polymorphic outer membrane protein repeat HRM2_RS10495 7786d52ab4c9e76de564fbe6c038438f 830 Gene3D G3DSA:2.160.20.10 213 392 2.4E-28 T 22-04-2016 IPR012334 Pectin lyase fold HRM2_RS10495 7786d52ab4c9e76de564fbe6c038438f 830 Gene3D G3DSA:2.160.20.10 49 175 2.4E-28 T 22-04-2016 IPR012334 Pectin lyase fold HRM2_RS10495 7786d52ab4c9e76de564fbe6c038438f 830 Gene3D G3DSA:2.160.20.10 479 810 5.3E-34 T 22-04-2016 IPR012334 Pectin lyase fold HRM2_RS10495 7786d52ab4c9e76de564fbe6c038438f 830 SUPERFAMILY SSF51126 478 811 1.11E-31 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor HRM2_RS10495 7786d52ab4c9e76de564fbe6c038438f 830 TIGRFAM TIGR01376 POMP_repeat: chlamydial polymorphic outer membrane protein repeat 295 312 0.0038 T 22-04-2016 IPR003368 Polymorphic outer membrane protein repeat HRM2_RS10495 7786d52ab4c9e76de564fbe6c038438f 830 SUPERFAMILY SSF51126 48 403 2.9E-23 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor HRM2_RS13200 0862864886f9f7ed83974f45ce2c6b55 104 Gene3D G3DSA:3.30.1390.10 5 104 2.0E-40 T 22-04-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like HRM2_RS13200 0862864886f9f7ed83974f45ce2c6b55 104 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 23 100 5.1E-33 T 22-04-2016 IPR003769 Adaptor protein ClpS, core GO:0030163 HRM2_RS13200 0862864886f9f7ed83974f45ce2c6b55 104 SUPERFAMILY SSF54736 19 103 7.32E-30 T 22-04-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like HRM2_RS13200 0862864886f9f7ed83974f45ce2c6b55 104 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 5 99 25.833 T 22-04-2016 IPR022935 ATP-dependent Clp protease adaptor protein ClpS HRM2_RS13200 0862864886f9f7ed83974f45ce2c6b55 104 PANTHER PTHR33473 5 104 5.3E-34 T 22-04-2016 HRM2_RS20720 89c085fedd7f83c56a22a1405a16103c 636 Gene3D G3DSA:3.40.50.1820 217 315 1.3E-7 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS20720 89c085fedd7f83c56a22a1405a16103c 636 Gene3D G3DSA:3.40.50.1820 434 465 1.3E-7 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS20720 89c085fedd7f83c56a22a1405a16103c 636 SUPERFAMILY SSF53474 389 488 1.26E-9 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS20720 89c085fedd7f83c56a22a1405a16103c 636 SUPERFAMILY SSF53474 186 324 1.26E-9 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS09195 1a1c50bea80a1c9857614f7e051576dd 88 PANTHER PTHR38449 2 87 7.6E-35 T 22-04-2016 HRM2_RS09195 1a1c50bea80a1c9857614f7e051576dd 88 Hamap MF_01503 UPF0296 protein . 3 87 26.641 T 22-04-2016 IPR007169 Uncharacterised protein family UPF0296 HRM2_RS09195 1a1c50bea80a1c9857614f7e051576dd 88 Pfam PF04025 Domain of unknown function (DUF370) 5 77 5.4E-34 T 22-04-2016 IPR007169 Uncharacterised protein family UPF0296 HRM2_RS09195 1a1c50bea80a1c9857614f7e051576dd 88 ProDom PD063023 UPF0296 YLZA BA4010/GBAA4010/BAS3723 BLI01788/BL02292 BT9727_3613 BC3870 TM1690 CBDBA43 SYC0519_C BCE33L3631 5 78 2.0E-25 T 22-04-2016 IPR007169 Uncharacterised protein family UPF0296 HRM2_RS08215 31a4cd6d64da3ef7ad8ff4502a2dc8a6 251 PANTHER PTHR30007 10 90 2.0E-18 T 22-04-2016 HRM2_RS08215 31a4cd6d64da3ef7ad8ff4502a2dc8a6 251 PANTHER PTHR30007:SF20 10 90 2.0E-18 T 22-04-2016 HRM2_RS08215 31a4cd6d64da3ef7ad8ff4502a2dc8a6 251 Gene3D G3DSA:3.20.20.140 10 91 1.4E-30 T 22-04-2016 HRM2_RS08215 31a4cd6d64da3ef7ad8ff4502a2dc8a6 251 Gene3D G3DSA:3.20.20.140 123 233 1.4E-30 T 22-04-2016 HRM2_RS08215 31a4cd6d64da3ef7ad8ff4502a2dc8a6 251 Pfam PF13263 PHP-associated 191 244 8.4E-12 T 22-04-2016 HRM2_RS08215 31a4cd6d64da3ef7ad8ff4502a2dc8a6 251 SUPERFAMILY SSF89550 9 89 9.55E-38 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 HRM2_RS08215 31a4cd6d64da3ef7ad8ff4502a2dc8a6 251 SUPERFAMILY SSF89550 133 247 9.55E-38 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 HRM2_RS08215 31a4cd6d64da3ef7ad8ff4502a2dc8a6 251 Pfam PF02811 PHP domain 12 109 4.9E-7 T 22-04-2016 IPR004013 PHP domain GO:0003824 HRM2_RS08215 31a4cd6d64da3ef7ad8ff4502a2dc8a6 251 SMART SM00481 11 79 2.1E-12 T 22-04-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 HRM2_RS03670 849b567d00d71e82e158d5ed8582c6b6 1252 SUPERFAMILY SSF53474 232 391 4.43E-6 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS03670 849b567d00d71e82e158d5ed8582c6b6 1252 Gene3D G3DSA:3.40.50.1820 414 439 4.3E-9 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS03670 849b567d00d71e82e158d5ed8582c6b6 1252 Gene3D G3DSA:3.40.50.1820 236 380 4.3E-9 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS03670 849b567d00d71e82e158d5ed8582c6b6 1252 Gene3D G3DSA:3.40.50.1460 1154 1250 1.7E-4 T 22-04-2016 IPR029030 Caspase-like domain HRM2_RS03670 849b567d00d71e82e158d5ed8582c6b6 1252 Pfam PF12770 CHAT domain 1046 1243 1.1E-23 T 22-04-2016 IPR024983 CHAT domain HRM2_RS07555 0ea10c696b84ae0b2792eb9cfb59c4ef 571 Pfam PF01163 RIO1 family 241 345 8.6E-5 T 22-04-2016 HRM2_RS07555 0ea10c696b84ae0b2792eb9cfb59c4ef 571 SUPERFAMILY SSF56112 100 163 2.29E-27 T 22-04-2016 IPR011009 Protein kinase-like domain HRM2_RS07555 0ea10c696b84ae0b2792eb9cfb59c4ef 571 SUPERFAMILY SSF56112 198 349 2.29E-27 T 22-04-2016 IPR011009 Protein kinase-like domain HRM2_RS07555 0ea10c696b84ae0b2792eb9cfb59c4ef 571 PANTHER PTHR10566 8 447 2.1E-137 T 22-04-2016 HRM2_RS07555 0ea10c696b84ae0b2792eb9cfb59c4ef 571 Pfam PF03109 ABC1 family 118 236 1.2E-31 T 22-04-2016 IPR004147 UbiB domain HRM2_RS07555 0ea10c696b84ae0b2792eb9cfb59c4ef 571 Gene3D G3DSA:3.90.1200.10 267 319 1.1E-7 T 22-04-2016 HRM2_RS13260 d1c9df8dd0f53663e8935ecccef59496 91 Pfam PF00216 Bacterial DNA-binding protein 1 89 8.4E-30 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 HRM2_RS13260 d1c9df8dd0f53663e8935ecccef59496 91 PANTHER PTHR33175 1 91 2.1E-34 T 22-04-2016 HRM2_RS13260 d1c9df8dd0f53663e8935ecccef59496 91 Gene3D G3DSA:4.10.520.10 1 90 1.9E-30 T 22-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 HRM2_RS13260 d1c9df8dd0f53663e8935ecccef59496 91 SUPERFAMILY SSF47729 1 90 6.18E-29 T 22-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 HRM2_RS13260 d1c9df8dd0f53663e8935ecccef59496 91 SMART SM00411 1 90 4.6E-30 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 HRM2_RS13260 d1c9df8dd0f53663e8935ecccef59496 91 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.7E-11 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 HRM2_RS13260 d1c9df8dd0f53663e8935ecccef59496 91 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.7E-11 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 HRM2_RS13260 d1c9df8dd0f53663e8935ecccef59496 91 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 1.7E-11 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 HRM2_RS06050 17be2cd7416113e6eb9468ce2a98a112 350 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 57 313 5.7E-34 T 22-04-2016 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 HRM2_RS06050 17be2cd7416113e6eb9468ce2a98a112 350 PANTHER PTHR33376 5 340 1.5E-47 T 22-04-2016 HRM2_RS22845 2503fdf78e5d510ba7ea0c55defb6fe9 423 PANTHER PTHR32027 1 412 5.4E-132 T 22-04-2016 HRM2_RS22845 2503fdf78e5d510ba7ea0c55defb6fe9 423 SUPERFAMILY SSF51556 52 371 1.96E-101 T 22-04-2016 IPR032466 Metal-dependent hydrolase HRM2_RS22845 2503fdf78e5d510ba7ea0c55defb6fe9 423 PANTHER PTHR32027:SF0 1 412 5.4E-132 T 22-04-2016 HRM2_RS22845 2503fdf78e5d510ba7ea0c55defb6fe9 423 Gene3D G3DSA:3.20.20.140 65 362 3.4E-108 T 22-04-2016 HRM2_RS22845 2503fdf78e5d510ba7ea0c55defb6fe9 423 SUPERFAMILY SSF51338 1 64 3.39E-12 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS22845 2503fdf78e5d510ba7ea0c55defb6fe9 423 Gene3D G3DSA:2.30.40.10 2 64 2.5E-10 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS22845 2503fdf78e5d510ba7ea0c55defb6fe9 423 Pfam PF07969 Amidohydrolase family 41 395 2.8E-36 T 22-04-2016 IPR013108 Amidohydrolase 3 HRM2_RS24335 4db14ef6bee36c573dd9181ddbc824c5 327 SUPERFAMILY SSF161098 187 306 1.52E-13 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS24335 4db14ef6bee36c573dd9181ddbc824c5 327 SUPERFAMILY SSF161098 90 158 1.52E-13 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS24335 4db14ef6bee36c573dd9181ddbc824c5 327 Gene3D G3DSA:1.10.3720.10 89 315 1.1E-13 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS24335 4db14ef6bee36c573dd9181ddbc824c5 327 PANTHER PTHR30465:SF47 1 323 1.3E-145 T 22-04-2016 HRM2_RS24335 4db14ef6bee36c573dd9181ddbc824c5 327 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 322 9.0E-37 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS24335 4db14ef6bee36c573dd9181ddbc824c5 327 PANTHER PTHR30465 1 323 1.3E-145 T 22-04-2016 HRM2_RS18320 c2df0fd091e5b4be2496809eb4bb3319 357 PANTHER PTHR30531:SF0 10 355 6.9E-135 T 22-04-2016 HRM2_RS18320 c2df0fd091e5b4be2496809eb4bb3319 357 SUPERFAMILY SSF160544 246 353 7.06E-37 T 22-04-2016 IPR029025 Type III secretion system substrate exporter, C-terminal HRM2_RS18320 c2df0fd091e5b4be2496809eb4bb3319 357 Pfam PF01312 FlhB HrpN YscU SpaS Family 9 349 6.2E-123 T 22-04-2016 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HRM2_RS18320 c2df0fd091e5b4be2496809eb4bb3319 357 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 12 34 6.8E-37 T 22-04-2016 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HRM2_RS18320 c2df0fd091e5b4be2496809eb4bb3319 357 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 230 247 6.8E-37 T 22-04-2016 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HRM2_RS18320 c2df0fd091e5b4be2496809eb4bb3319 357 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 210 228 6.8E-37 T 22-04-2016 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HRM2_RS18320 c2df0fd091e5b4be2496809eb4bb3319 357 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 274 289 6.8E-37 T 22-04-2016 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HRM2_RS18320 c2df0fd091e5b4be2496809eb4bb3319 357 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 304 325 6.8E-37 T 22-04-2016 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HRM2_RS18320 c2df0fd091e5b4be2496809eb4bb3319 357 Gene3D G3DSA:3.40.1690.10 220 354 2.6E-55 T 22-04-2016 IPR029025 Type III secretion system substrate exporter, C-terminal HRM2_RS18320 c2df0fd091e5b4be2496809eb4bb3319 357 PANTHER PTHR30531 10 355 6.9E-135 T 22-04-2016 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HRM2_RS18320 c2df0fd091e5b4be2496809eb4bb3319 357 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 10 354 1.2E-120 T 22-04-2016 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 HRM2_RS20140 112120438f1e88814795f57f288d49a3 272 SUPERFAMILY SSF161098 69 260 1.44E-45 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS20140 112120438f1e88814795f57f288d49a3 272 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 69 163 5.2E-26 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HRM2_RS20140 112120438f1e88814795f57f288d49a3 272 PANTHER PTHR30614 28 268 8.2E-83 T 22-04-2016 HRM2_RS20140 112120438f1e88814795f57f288d49a3 272 Gene3D G3DSA:1.10.3720.10 68 270 7.3E-50 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS20140 112120438f1e88814795f57f288d49a3 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 268 1.6E-20 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS02900 d253674ce476d4816f6bc72875755b8a 186 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 117 164 3.0E-6 T 22-04-2016 IPR019264 Domain of unknown function DUF2179 HRM2_RS02900 d253674ce476d4816f6bc72875755b8a 186 PANTHER PTHR40060 3 165 1.9E-30 T 22-04-2016 HRM2_RS09230 7c3ba75a0f0964c15d6ea38886e4a227 66 Gene3D G3DSA:3.30.429.20 1 61 8.9E-27 T 22-04-2016 HRM2_RS09230 7c3ba75a0f0964c15d6ea38886e4a227 66 Pfam PF01361 Tautomerase enzyme 2 61 9.0E-21 T 22-04-2016 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 HRM2_RS09230 7c3ba75a0f0964c15d6ea38886e4a227 66 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 63 8.2E-25 T 22-04-2016 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 HRM2_RS09230 7c3ba75a0f0964c15d6ea38886e4a227 66 PANTHER PTHR35530:SF1 1 65 3.0E-21 T 22-04-2016 HRM2_RS09230 7c3ba75a0f0964c15d6ea38886e4a227 66 SUPERFAMILY SSF55331 2 64 1.69E-20 T 22-04-2016 IPR014347 Tautomerase/MIF superfamily HRM2_RS09230 7c3ba75a0f0964c15d6ea38886e4a227 66 PANTHER PTHR35530 1 65 3.0E-21 T 22-04-2016 HRM2_RS22530 28d7140c6d8f30c09dc705d324646c86 253 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 10 247 8.1E-33 T 22-04-2016 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00148 HRM2_RS22530 28d7140c6d8f30c09dc705d324646c86 253 PANTHER PTHR34148 1 248 4.4E-38 T 22-04-2016 HRM2_RS22530 28d7140c6d8f30c09dc705d324646c86 253 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 253 35.216 T 22-04-2016 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00148 HRM2_RS22530 28d7140c6d8f30c09dc705d324646c86 253 PANTHER PTHR34148:SF1 1 248 4.4E-38 T 22-04-2016 HRM2_RS22530 28d7140c6d8f30c09dc705d324646c86 253 Pfam PF02654 Cobalamin-5-phosphate synthase 14 245 1.7E-45 T 22-04-2016 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00148 HRM2_RS12390 5d5bad7fb13ca61180e9d94358340ec5 420 PANTHER PTHR34388 1 287 9.6E-29 T 22-04-2016 HRM2_RS12390 5d5bad7fb13ca61180e9d94358340ec5 420 Pfam PF06144 DNA polymerase III, delta subunit 27 207 1.3E-9 T 22-04-2016 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 HRM2_RS12390 5d5bad7fb13ca61180e9d94358340ec5 420 SUPERFAMILY SSF52540 4 226 3.32E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12390 5d5bad7fb13ca61180e9d94358340ec5 420 Gene3D G3DSA:1.10.8.60 165 248 1.4E-9 T 22-04-2016 HRM2_RS12390 5d5bad7fb13ca61180e9d94358340ec5 420 SUPERFAMILY SSF48019 233 318 1.47E-9 T 22-04-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 HRM2_RS03405 a55da73121f7b24cf5e0b949769c92d9 456 Gene3D G3DSA:3.40.50.980 104 259 6.6E-12 T 22-04-2016 HRM2_RS03405 a55da73121f7b24cf5e0b949769c92d9 456 PANTHER PTHR36932 31 343 7.4E-33 T 22-04-2016 HRM2_RS03405 a55da73121f7b24cf5e0b949769c92d9 456 Pfam PF00501 AMP-binding enzyme 106 302 2.7E-13 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS03405 a55da73121f7b24cf5e0b949769c92d9 456 SUPERFAMILY SSF56801 53 427 1.83E-34 T 22-04-2016 HRM2_RS03405 a55da73121f7b24cf5e0b949769c92d9 456 PANTHER PTHR36932:SF1 31 343 7.4E-33 T 22-04-2016 HRM2_RS01705 b926cccc2a87f8de64648c9b6a484e1a 383 PANTHER PTHR30269:SF9 60 231 1.8E-32 T 22-04-2016 HRM2_RS01705 b926cccc2a87f8de64648c9b6a484e1a 383 PANTHER PTHR30269:SF9 256 380 1.8E-32 T 22-04-2016 HRM2_RS01705 b926cccc2a87f8de64648c9b6a484e1a 383 PANTHER PTHR30269 60 231 1.8E-32 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 HRM2_RS01705 b926cccc2a87f8de64648c9b6a484e1a 383 PANTHER PTHR30269 256 380 1.8E-32 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 HRM2_RS01705 b926cccc2a87f8de64648c9b6a484e1a 383 Pfam PF01925 Sulfite exporter TauE/SafE 69 369 2.4E-33 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 HRM2_RS21695 ae8a0ae83af7c2183c6388f160474016 204 SUPERFAMILY SSF50475 12 203 1.78E-29 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 HRM2_RS21695 ae8a0ae83af7c2183c6388f160474016 204 Pfam PF12766 Pyridoxamine 5'-phosphate oxidase 19 106 3.5E-19 T 22-04-2016 IPR024624 Pyridoxamine 5'-phosphate oxidase, Alr4036 family, FMN-binding domain GO:0010181 HRM2_RS21695 ae8a0ae83af7c2183c6388f160474016 204 Gene3D G3DSA:2.30.110.10 11 204 6.1E-48 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 HRM2_RS23750 84f0e4236591dc69087bd78a143a27ec 446 Pfam PF05065 Phage capsid family 144 429 4.6E-30 T 22-04-2016 IPR024455 Phage capsid HRM2_RS23750 84f0e4236591dc69087bd78a143a27ec 446 SUPERFAMILY SSF56563 139 429 7.06E-33 T 22-04-2016 HRM2_RS23750 84f0e4236591dc69087bd78a143a27ec 446 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 3 430 9.7E-48 T 22-04-2016 IPR006444 Phage major capsid protein, HK97 HRM2_RS22335 4073c18e546a8055c6749688210ecf56 393 Gene3D G3DSA:3.40.47.10 147 187 1.1E-19 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS22335 4073c18e546a8055c6749688210ecf56 393 Gene3D G3DSA:3.40.47.10 248 361 1.1E-19 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS22335 4073c18e546a8055c6749688210ecf56 393 PANTHER PTHR18919:SF8 1 391 9.0E-111 T 22-04-2016 HRM2_RS22335 4073c18e546a8055c6749688210ecf56 393 PANTHER PTHR18919 1 391 9.0E-111 T 22-04-2016 HRM2_RS22335 4073c18e546a8055c6749688210ecf56 393 PIRSF PIRSF000429 1 386 4.9E-60 T 22-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 HRM2_RS22335 4073c18e546a8055c6749688210ecf56 393 Gene3D G3DSA:3.40.47.10 19 113 6.7E-27 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS22335 4073c18e546a8055c6749688210ecf56 393 Gene3D G3DSA:3.40.47.10 206 230 6.7E-27 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS22335 4073c18e546a8055c6749688210ecf56 393 Pfam PF02803 Thiolase, C-terminal domain 267 357 3.7E-10 T 22-04-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 HRM2_RS22335 4073c18e546a8055c6749688210ecf56 393 Pfam PF00108 Thiolase, N-terminal domain 4 228 4.1E-25 T 22-04-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 HRM2_RS22335 4073c18e546a8055c6749688210ecf56 393 SUPERFAMILY SSF53901 185 356 5.49E-44 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS22335 4073c18e546a8055c6749688210ecf56 393 SUPERFAMILY SSF53901 5 120 5.49E-44 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HRM2_RS19620 470deeb65541b58449dc4dc282a83c55 236 PANTHER PTHR35811:SF1 3 233 7.7E-56 T 22-04-2016 HRM2_RS19620 470deeb65541b58449dc4dc282a83c55 236 Gene3D G3DSA:3.40.50.1010 2 144 9.3E-27 T 22-04-2016 IPR029060 PIN domain-like HRM2_RS19620 470deeb65541b58449dc4dc282a83c55 236 Pfam PF01936 NYN domain 7 142 5.8E-31 T 22-04-2016 IPR021139 NYN domain, limkain-b1-type HRM2_RS19620 470deeb65541b58449dc4dc282a83c55 236 Pfam PF12872 OST-HTH/LOTUS domain 159 228 9.0E-15 T 22-04-2016 IPR025605 OST-HTH/LOTUS domain HRM2_RS19620 470deeb65541b58449dc4dc282a83c55 236 PANTHER PTHR35811 3 233 7.7E-56 T 22-04-2016 HRM2_RS25670 058ebab6c2e7901165ff80d5199e149f 152 PANTHER PTHR35867 3 149 6.6E-13 T 22-04-2016 HRM2_RS25670 058ebab6c2e7901165ff80d5199e149f 152 PANTHER PTHR35867:SF1 3 149 6.6E-13 T 22-04-2016 HRM2_RS25670 058ebab6c2e7901165ff80d5199e149f 152 PIRSF PIRSF004923 1 149 7.7E-22 T 22-04-2016 IPR026268 Protein RseC HRM2_RS25670 058ebab6c2e7901165ff80d5199e149f 152 Pfam PF04246 Positive regulator of sigma(E), RseC/MucC 14 141 7.8E-28 T 22-04-2016 IPR007359 Positive regulator of sigma(E), RseC/MucC HRM2_RS07950 cd31577fa43c2315548f038d8e018b6c 369 Gene3D G3DSA:1.20.970.10 12 70 1.3E-15 T 22-04-2016 HRM2_RS07950 cd31577fa43c2315548f038d8e018b6c 369 SUPERFAMILY SSF47648 12 71 1.7E-13 T 22-04-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain HRM2_RS07950 cd31577fa43c2315548f038d8e018b6c 369 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 14 352 3.0E-65 T 22-04-2016 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18|UniPathway: UPA00035 HRM2_RS07950 cd31577fa43c2315548f038d8e018b6c 369 Pfam PF00591 Glycosyl transferase family, a/b domain 82 343 2.2E-46 T 22-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 HRM2_RS07950 cd31577fa43c2315548f038d8e018b6c 369 Pfam PF02885 Glycosyl transferase family, helical bundle domain 12 68 5.3E-13 T 22-04-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain HRM2_RS07950 cd31577fa43c2315548f038d8e018b6c 369 PANTHER PTHR11922 87 360 1.5E-42 T 22-04-2016 HRM2_RS07950 cd31577fa43c2315548f038d8e018b6c 369 SUPERFAMILY SSF52418 84 351 6.93E-47 T 22-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 HRM2_RS07950 cd31577fa43c2315548f038d8e018b6c 369 Gene3D G3DSA:3.40.1030.10 85 158 8.1E-61 T 22-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 HRM2_RS07950 cd31577fa43c2315548f038d8e018b6c 369 Gene3D G3DSA:3.40.1030.10 191 358 8.1E-61 T 22-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 HRM2_RS07950 cd31577fa43c2315548f038d8e018b6c 369 PANTHER PTHR11922:SF5 87 360 1.5E-42 T 22-04-2016 HRM2_RS02920 5ecf1e5776cca842d6c0280962340ee6 153 PANTHER PTHR12418 21 146 1.4E-30 T 22-04-2016 HRM2_RS02920 5ecf1e5776cca842d6c0280962340ee6 153 Pfam PF03061 Thioesterase superfamily 47 125 2.0E-16 T 22-04-2016 IPR006683 Thioesterase domain HRM2_RS02920 5ecf1e5776cca842d6c0280962340ee6 153 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 21 131 5.2E-24 T 22-04-2016 IPR003736 Phenylacetic acid degradation-related domain HRM2_RS02920 5ecf1e5776cca842d6c0280962340ee6 153 Gene3D G3DSA:3.10.129.10 15 136 1.6E-39 T 22-04-2016 IPR029069 HotDog domain HRM2_RS02920 5ecf1e5776cca842d6c0280962340ee6 153 PANTHER PTHR12418:SF33 21 146 1.4E-30 T 22-04-2016 HRM2_RS02920 5ecf1e5776cca842d6c0280962340ee6 153 SUPERFAMILY SSF54637 15 136 2.66E-27 T 22-04-2016 IPR029069 HotDog domain HRM2_RS11110 b9a3687111a3854e0a12ac8931bccaba 179 PANTHER PTHR35089:SF1 6 177 1.2E-26 T 22-04-2016 HRM2_RS11110 b9a3687111a3854e0a12ac8931bccaba 179 SUPERFAMILY SSF111384 28 171 6.15E-25 T 22-04-2016 IPR024930 Skp domain HRM2_RS11110 b9a3687111a3854e0a12ac8931bccaba 179 Pfam PF03938 Outer membrane protein (OmpH-like) 14 169 3.9E-32 T 22-04-2016 IPR005632 Chaperone protein Skp GO:0051082 HRM2_RS11110 b9a3687111a3854e0a12ac8931bccaba 179 SMART SM00935 14 171 6.1E-38 T 22-04-2016 IPR005632 Chaperone protein Skp GO:0051082 HRM2_RS11110 b9a3687111a3854e0a12ac8931bccaba 179 Gene3D G3DSA:3.30.910.20 101 170 1.2E-16 T 22-04-2016 HRM2_RS11110 b9a3687111a3854e0a12ac8931bccaba 179 Gene3D G3DSA:3.30.910.20 18 63 1.2E-16 T 22-04-2016 HRM2_RS11110 b9a3687111a3854e0a12ac8931bccaba 179 PANTHER PTHR35089 6 177 1.2E-26 T 22-04-2016 HRM2_RS21935 21d7af8510264474a4b82703d79e1f7c 432 PANTHER PTHR37419 147 355 4.7E-17 T 22-04-2016 HRM2_RS21935 21d7af8510264474a4b82703d79e1f7c 432 Pfam PF07804 HipA-like C-terminal domain 269 408 3.6E-30 T 22-04-2016 IPR012893 HipA-like, C-terminal HRM2_RS21935 21d7af8510264474a4b82703d79e1f7c 432 Pfam PF07805 HipA-like N-terminal domain 192 263 2.6E-12 T 22-04-2016 IPR012894 HipA, N-terminal subdomain 2 HRM2_RS07750 7de4522b1a43cc641aca7aad8dcf6210 191 SMART SM00347 50 153 8.1E-10 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS07750 7de4522b1a43cc641aca7aad8dcf6210 191 Pfam PF01047 MarR family 78 118 6.8E-8 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS07750 7de4522b1a43cc641aca7aad8dcf6210 191 SUPERFAMILY SSF46785 38 167 5.01E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS07750 7de4522b1a43cc641aca7aad8dcf6210 191 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 109 1.4E-8 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS07750 7de4522b1a43cc641aca7aad8dcf6210 191 PRINTS PR00598 Bacterial regulatory protein MarR family signature 143 163 1.4E-8 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS07750 7de4522b1a43cc641aca7aad8dcf6210 191 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 129 1.4E-8 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS07750 7de4522b1a43cc641aca7aad8dcf6210 191 PANTHER PTHR33164 1 177 2.3E-17 T 22-04-2016 HRM2_RS07750 7de4522b1a43cc641aca7aad8dcf6210 191 Gene3D G3DSA:1.10.10.10 44 168 1.0E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS07685 b92a50d9a55b7dbab01d67f785ea5e07 423 PANTHER PTHR10120 8 414 2.0E-123 T 22-04-2016 HRM2_RS07685 b92a50d9a55b7dbab01d67f785ea5e07 423 Pfam PF16491 CAAX prenyl protease N-terminal, five membrane helices 37 205 1.7E-51 T 22-04-2016 IPR032456 CAAX prenyl protease 1, N-terminal KEGG: 00900+3.4.24.84 HRM2_RS07685 b92a50d9a55b7dbab01d67f785ea5e07 423 Pfam PF01435 Peptidase family M48 208 414 1.7E-42 T 22-04-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 HRM2_RS07685 b92a50d9a55b7dbab01d67f785ea5e07 423 PANTHER PTHR10120:SF24 8 414 2.0E-123 T 22-04-2016 IPR027057 CAAX prenyl protease 1 GO:0008233|GO:0071586 KEGG: 00900+3.4.24.84 HRM2_RS07685 b92a50d9a55b7dbab01d67f785ea5e07 423 Gene3D G3DSA:3.30.2010.10 202 294 7.6E-17 T 22-04-2016 HRM2_RS21540 e3f2ad4d5293f6abce4dfbeda0d18e0f 248 Gene3D G3DSA:3.40.50.300 1 236 3.2E-82 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21540 e3f2ad4d5293f6abce4dfbeda0d18e0f 248 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS21540 e3f2ad4d5293f6abce4dfbeda0d18e0f 248 SMART SM00382 26 213 1.7E-16 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS21540 e3f2ad4d5293f6abce4dfbeda0d18e0f 248 PANTHER PTHR24220 3 240 1.5E-132 T 22-04-2016 HRM2_RS21540 e3f2ad4d5293f6abce4dfbeda0d18e0f 248 PANTHER PTHR24220:SF474 3 240 1.5E-132 T 22-04-2016 HRM2_RS21540 e3f2ad4d5293f6abce4dfbeda0d18e0f 248 PIRSF PIRSF039085 1 241 1.2E-102 T 22-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 HRM2_RS21540 e3f2ad4d5293f6abce4dfbeda0d18e0f 248 Pfam PF00005 ABC transporter 18 165 5.3E-36 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS21540 e3f2ad4d5293f6abce4dfbeda0d18e0f 248 SUPERFAMILY SSF52540 1 235 2.72E-77 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16270 47cf1f450cd7a86887101de7df2a3189 290 PANTHER PTHR22911 4 287 6.6E-25 T 22-04-2016 HRM2_RS16270 47cf1f450cd7a86887101de7df2a3189 290 SUPERFAMILY SSF103481 194 288 4.71E-9 T 22-04-2016 HRM2_RS16270 47cf1f450cd7a86887101de7df2a3189 290 Pfam PF00892 EamA-like transporter family 153 287 4.3E-12 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS16270 47cf1f450cd7a86887101de7df2a3189 290 Pfam PF00892 EamA-like transporter family 4 132 3.2E-10 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS16270 47cf1f450cd7a86887101de7df2a3189 290 SUPERFAMILY SSF103481 43 136 3.01E-12 T 22-04-2016 HRM2_RS03355 837a33e4479323e61d117a9b31a99d75 442 PANTHER PTHR37839:SF1 1 442 2.0E-79 T 22-04-2016 HRM2_RS03355 837a33e4479323e61d117a9b31a99d75 442 Hamap MF_00425 Na(+)-translocating NADH-quinone reductase subunit A [nqrA]. 3 441 32.357 T 22-04-2016 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 HRM2_RS03355 837a33e4479323e61d117a9b31a99d75 442 Pfam PF05896 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) 3 259 2.6E-53 T 22-04-2016 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 HRM2_RS03355 837a33e4479323e61d117a9b31a99d75 442 PANTHER PTHR37839 1 442 2.0E-79 T 22-04-2016 HRM2_RS03355 837a33e4479323e61d117a9b31a99d75 442 Gene3D G3DSA:1.10.1060.10 367 435 1.3E-11 T 22-04-2016 HRM2_RS03355 837a33e4479323e61d117a9b31a99d75 442 Gene3D G3DSA:2.40.50.100 43 85 2.3E-4 T 22-04-2016 HRM2_RS03355 837a33e4479323e61d117a9b31a99d75 442 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 410 421 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS03355 837a33e4479323e61d117a9b31a99d75 442 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 371 382 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS03355 837a33e4479323e61d117a9b31a99d75 442 SUPERFAMILY SSF46548 368 433 5.89E-11 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS13220 bdd69987f6515b96388f2b9ba5449268 576 PANTHER PTHR33362 45 570 1.0E-182 T 22-04-2016 HRM2_RS13220 bdd69987f6515b96388f2b9ba5449268 576 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 12 568 1.7E-169 T 22-04-2016 IPR011853 TRAP transporter, 4TM/12TM fusion protein HRM2_RS13220 bdd69987f6515b96388f2b9ba5449268 576 PANTHER PTHR33362:SF1 45 570 1.0E-182 T 22-04-2016 HRM2_RS13220 bdd69987f6515b96388f2b9ba5449268 576 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 104 531 1.5E-78 T 22-04-2016 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit HRM2_RS07460 4bd92bba381223c3a63ffb47ba1cb860 329 PANTHER PTHR11695:SF294 15 329 2.1E-97 T 22-04-2016 HRM2_RS07460 4bd92bba381223c3a63ffb47ba1cb860 329 SUPERFAMILY SSF51735 120 297 3.12E-37 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS07460 4bd92bba381223c3a63ffb47ba1cb860 329 SUPERFAMILY SSF50129 1 154 1.31E-38 T 22-04-2016 IPR011032 GroES-like HRM2_RS07460 4bd92bba381223c3a63ffb47ba1cb860 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 89 3.0E-8 T 22-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 HRM2_RS07460 4bd92bba381223c3a63ffb47ba1cb860 329 Gene3D G3DSA:3.40.50.720 152 261 7.7E-24 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS07460 4bd92bba381223c3a63ffb47ba1cb860 329 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 147 168 - T 22-04-2016 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 HRM2_RS07460 4bd92bba381223c3a63ffb47ba1cb860 329 SMART SM00829 10 327 2.0E-41 T 22-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 HRM2_RS07460 4bd92bba381223c3a63ffb47ba1cb860 329 PANTHER PTHR11695 15 329 2.1E-97 T 22-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 HRM2_RS07460 4bd92bba381223c3a63ffb47ba1cb860 329 Gene3D G3DSA:3.90.180.10 1 151 2.9E-47 T 22-04-2016 IPR011032 GroES-like HRM2_RS07460 4bd92bba381223c3a63ffb47ba1cb860 329 Pfam PF13602 Zinc-binding dehydrogenase 193 327 5.2E-20 T 22-04-2016 HRM2_RS02835 8c8810f5c9a2ad77a029c8c10b7f06e8 297 Pfam PF14236 Domain of unknown function (DUF4338) 66 294 3.3E-81 T 22-04-2016 IPR025639 Domain of unknown function DUF4338 HRM2_RS06835 a52babd22502d5bee4e50605d4d27dc3 284 SUPERFAMILY SSF161098 5 274 3.4E-51 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS06835 a52babd22502d5bee4e50605d4d27dc3 284 PANTHER PTHR30193 16 282 1.1E-102 T 22-04-2016 HRM2_RS06835 a52babd22502d5bee4e50605d4d27dc3 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 281 6.8E-16 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS06835 a52babd22502d5bee4e50605d4d27dc3 284 PANTHER PTHR30193:SF10 16 282 1.1E-102 T 22-04-2016 HRM2_RS06835 a52babd22502d5bee4e50605d4d27dc3 284 Gene3D G3DSA:1.10.3720.10 4 269 4.4E-47 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS19840 6284324d0717cde89363237bcf26ff60 476 Gene3D G3DSA:3.40.50.2300 4 140 4.3E-34 T 22-04-2016 HRM2_RS19840 6284324d0717cde89363237bcf26ff60 476 SUPERFAMILY SSF46689 409 468 1.75E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS19840 6284324d0717cde89363237bcf26ff60 476 SMART SM00382 162 305 2.6E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS19840 6284324d0717cde89363237bcf26ff60 476 Pfam PF00158 Sigma-54 interaction domain 142 308 2.2E-69 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 HRM2_RS19840 6284324d0717cde89363237bcf26ff60 476 SMART SM00448 2 113 1.1E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS19840 6284324d0717cde89363237bcf26ff60 476 Pfam PF02954 Bacterial regulatory protein, Fis family 433 466 6.1E-11 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS19840 6284324d0717cde89363237bcf26ff60 476 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 355 364 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site HRM2_RS19840 6284324d0717cde89363237bcf26ff60 476 Gene3D G3DSA:1.10.8.60 315 387 9.5E-19 T 22-04-2016 HRM2_RS19840 6284324d0717cde89363237bcf26ff60 476 Gene3D G3DSA:3.40.50.300 141 314 2.7E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19840 6284324d0717cde89363237bcf26ff60 476 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 432 449 1.2E-11 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS19840 6284324d0717cde89363237bcf26ff60 476 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 449 469 1.2E-11 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 HRM2_RS19840 6284324d0717cde89363237bcf26ff60 476 SUPERFAMILY SSF52540 142 383 3.06E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19840 6284324d0717cde89363237bcf26ff60 476 Pfam PF00072 Response regulator receiver domain 4 111 1.7E-27 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS19840 6284324d0717cde89363237bcf26ff60 476 SUPERFAMILY SSF52172 4 187 4.13E-37 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS19840 6284324d0717cde89363237bcf26ff60 476 PANTHER PTHR32071 4 476 4.6E-180 T 22-04-2016 HRM2_RS19840 6284324d0717cde89363237bcf26ff60 476 Gene3D G3DSA:1.10.10.60 414 468 2.0E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS18425 f8dce2bff0a087b28eb58ce6d67cd030 850 Gene3D G3DSA:1.25.40.10 609 829 8.3E-16 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS18425 f8dce2bff0a087b28eb58ce6d67cd030 850 SMART SM00028 307 340 140.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS18425 f8dce2bff0a087b28eb58ce6d67cd030 850 SMART SM00028 527 560 93.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS18425 f8dce2bff0a087b28eb58ce6d67cd030 850 SMART SM00028 419 452 2.5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS18425 f8dce2bff0a087b28eb58ce6d67cd030 850 SMART SM00028 759 792 19.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS18425 f8dce2bff0a087b28eb58ce6d67cd030 850 SMART SM00028 344 377 5.4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS18425 f8dce2bff0a087b28eb58ce6d67cd030 850 SMART SM00028 606 639 470.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS18425 f8dce2bff0a087b28eb58ce6d67cd030 850 SMART SM00028 796 829 110.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS18425 f8dce2bff0a087b28eb58ce6d67cd030 850 Gene3D G3DSA:1.25.40.10 401 489 6.5E-11 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS18425 f8dce2bff0a087b28eb58ce6d67cd030 850 Gene3D G3DSA:1.25.40.10 527 559 6.5E-11 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS18425 f8dce2bff0a087b28eb58ce6d67cd030 850 SUPERFAMILY SSF48452 751 823 6.07E-8 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS18425 f8dce2bff0a087b28eb58ce6d67cd030 850 SUPERFAMILY SSF48452 604 721 6.07E-8 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS18425 f8dce2bff0a087b28eb58ce6d67cd030 850 SUPERFAMILY SSF48452 417 487 1.46E-9 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS18425 f8dce2bff0a087b28eb58ce6d67cd030 850 SUPERFAMILY SSF48452 602 673 1.46E-9 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS18425 f8dce2bff0a087b28eb58ce6d67cd030 850 SUPERFAMILY SSF48452 531 561 1.46E-9 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS18425 f8dce2bff0a087b28eb58ce6d67cd030 850 Gene3D G3DSA:1.25.40.10 288 400 1.7E-12 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS18425 f8dce2bff0a087b28eb58ce6d67cd030 850 Pfam PF13432 Tetratricopeptide repeat 289 341 4.4E-4 T 22-04-2016 HRM2_RS18425 f8dce2bff0a087b28eb58ce6d67cd030 850 SUPERFAMILY SSF48452 288 451 4.24E-15 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS18425 f8dce2bff0a087b28eb58ce6d67cd030 850 Pfam PF13174 Tetratricopeptide repeat 646 676 0.012 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS18425 f8dce2bff0a087b28eb58ce6d67cd030 850 Pfam PF13174 Tetratricopeptide repeat 422 451 0.035 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS18425 f8dce2bff0a087b28eb58ce6d67cd030 850 Pfam PF13181 Tetratricopeptide repeat 344 371 0.002 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS18425 f8dce2bff0a087b28eb58ce6d67cd030 850 PANTHER PTHR23083 529 560 1.1E-25 T 22-04-2016 HRM2_RS18425 f8dce2bff0a087b28eb58ce6d67cd030 850 PANTHER PTHR23083 642 828 1.1E-25 T 22-04-2016 HRM2_RS18425 f8dce2bff0a087b28eb58ce6d67cd030 850 PANTHER PTHR23083 289 491 1.1E-25 T 22-04-2016 HRM2_RS14795 8bf3a8bf8f02fa81fc79746ae6779b89 484 PANTHER PTHR11228:SF7 9 307 6.5E-31 T 22-04-2016 HRM2_RS14795 8bf3a8bf8f02fa81fc79746ae6779b89 484 PANTHER PTHR11228 9 307 6.5E-31 T 22-04-2016 HRM2_RS14795 8bf3a8bf8f02fa81fc79746ae6779b89 484 SUPERFAMILY SSF102114 8 311 1.83E-39 T 22-04-2016 HRM2_RS14795 8bf3a8bf8f02fa81fc79746ae6779b89 484 Gene3D G3DSA:3.20.20.70 4 309 1.3E-36 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS14795 8bf3a8bf8f02fa81fc79746ae6779b89 484 Pfam PF13186 Iron-sulfur cluster-binding domain 249 308 1.8E-9 T 22-04-2016 IPR023885 4Fe4S-binding SPASM domain HRM2_RS14795 8bf3a8bf8f02fa81fc79746ae6779b89 484 Pfam PF04055 Radical SAM superfamily 13 154 2.6E-8 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS13865 180f03fc264d127a22f3858bb5b11168 470 SUPERFAMILY SSF55073 314 469 1.02E-49 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS13865 180f03fc264d127a22f3858bb5b11168 470 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 305 469 3.4E-53 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS13865 180f03fc264d127a22f3858bb5b11168 470 SMART SM00267 298 470 4.7E-62 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS13865 180f03fc264d127a22f3858bb5b11168 470 Pfam PF00990 Diguanylate cyclase, GGDEF domain 310 466 4.6E-48 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS13865 180f03fc264d127a22f3858bb5b11168 470 PANTHER PTHR10799:SF710 342 466 2.6E-26 T 22-04-2016 HRM2_RS13865 180f03fc264d127a22f3858bb5b11168 470 PANTHER PTHR10799:SF710 129 268 2.6E-26 T 22-04-2016 HRM2_RS13865 180f03fc264d127a22f3858bb5b11168 470 PANTHER PTHR10799 342 466 2.6E-26 T 22-04-2016 HRM2_RS13865 180f03fc264d127a22f3858bb5b11168 470 PANTHER PTHR10799 129 268 2.6E-26 T 22-04-2016 HRM2_RS13865 180f03fc264d127a22f3858bb5b11168 470 Gene3D G3DSA:3.30.70.270 311 469 2.7E-56 T 22-04-2016 HRM2_RS08815 49c7408bc3d7d690f428dd66a4c15d65 189 PRINTS PR00096 Glutamine amidotransferase superfamily signature 165 178 1.1E-13 T 22-04-2016 HRM2_RS08815 49c7408bc3d7d690f428dd66a4c15d65 189 PRINTS PR00096 Glutamine amidotransferase superfamily signature 48 57 1.1E-13 T 22-04-2016 HRM2_RS08815 49c7408bc3d7d690f428dd66a4c15d65 189 PRINTS PR00096 Glutamine amidotransferase superfamily signature 75 86 1.1E-13 T 22-04-2016 HRM2_RS08815 49c7408bc3d7d690f428dd66a4c15d65 189 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 45 59 1.7E-7 T 22-04-2016 HRM2_RS08815 49c7408bc3d7d690f428dd66a4c15d65 189 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 75 91 1.7E-7 T 22-04-2016 HRM2_RS08815 49c7408bc3d7d690f428dd66a4c15d65 189 PRINTS PR00097 Anthranilate synthase component II signature 100 108 1.4E-33 T 22-04-2016 HRM2_RS08815 49c7408bc3d7d690f428dd66a4c15d65 189 PRINTS PR00097 Anthranilate synthase component II signature 165 178 1.4E-33 T 22-04-2016 HRM2_RS08815 49c7408bc3d7d690f428dd66a4c15d65 189 PRINTS PR00097 Anthranilate synthase component II signature 3 17 1.4E-33 T 22-04-2016 HRM2_RS08815 49c7408bc3d7d690f428dd66a4c15d65 189 PRINTS PR00097 Anthranilate synthase component II signature 120 132 1.4E-33 T 22-04-2016 HRM2_RS08815 49c7408bc3d7d690f428dd66a4c15d65 189 PRINTS PR00097 Anthranilate synthase component II signature 48 57 1.4E-33 T 22-04-2016 HRM2_RS08815 49c7408bc3d7d690f428dd66a4c15d65 189 PRINTS PR00097 Anthranilate synthase component II signature 75 86 1.4E-33 T 22-04-2016 HRM2_RS08815 49c7408bc3d7d690f428dd66a4c15d65 189 PANTHER PTHR11922 3 187 6.1E-87 T 22-04-2016 HRM2_RS08815 49c7408bc3d7d690f428dd66a4c15d65 189 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 3 187 5.9E-71 T 22-04-2016 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 HRM2_RS08815 49c7408bc3d7d690f428dd66a4c15d65 189 Pfam PF00117 Glutamine amidotransferase class-I 5 186 3.6E-53 T 22-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 HRM2_RS08815 49c7408bc3d7d690f428dd66a4c15d65 189 Gene3D G3DSA:3.40.50.880 3 188 2.0E-63 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS08815 49c7408bc3d7d690f428dd66a4c15d65 189 PANTHER PTHR11922:SF7 3 187 6.1E-87 T 22-04-2016 HRM2_RS08815 49c7408bc3d7d690f428dd66a4c15d65 189 SUPERFAMILY SSF52317 1 187 2.38E-54 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS03245 1f0fa54fd6616a17a0df36cbde146d2a 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 42 3.0E-10 T 22-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS03245 1f0fa54fd6616a17a0df36cbde146d2a 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.574 T 22-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS03245 1f0fa54fd6616a17a0df36cbde146d2a 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 22-04-2016 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS03245 1f0fa54fd6616a17a0df36cbde146d2a 44 PANTHER PTHR14503 1 44 1.4E-16 T 22-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS03245 1f0fa54fd6616a17a0df36cbde146d2a 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 3.6E-20 T 22-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS03245 1f0fa54fd6616a17a0df36cbde146d2a 44 Pfam PF00468 Ribosomal protein L34 1 44 6.2E-21 T 22-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS13980 934ecd7370fc00dece96e0b06ef3d653 143 SUPERFAMILY SSF75169 27 142 1.84E-14 T 22-04-2016 IPR027396 DsrEFH-like HRM2_RS13980 934ecd7370fc00dece96e0b06ef3d653 143 Gene3D G3DSA:3.40.1260.10 30 143 4.8E-10 T 22-04-2016 IPR027396 DsrEFH-like HRM2_RS18895 76d67841f9800f1d04cac6e0e8ae77c2 304 SUPERFAMILY SSF52172 3 121 5.55E-35 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS18895 76d67841f9800f1d04cac6e0e8ae77c2 304 Pfam PF00571 CBS domain 134 201 4.1E-7 T 22-04-2016 IPR000644 CBS domain HRM2_RS18895 76d67841f9800f1d04cac6e0e8ae77c2 304 SMART SM00448 5 116 8.1E-31 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18895 76d67841f9800f1d04cac6e0e8ae77c2 304 Pfam PF00072 Response regulator receiver domain 7 116 1.3E-26 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18895 76d67841f9800f1d04cac6e0e8ae77c2 304 Gene3D G3DSA:3.10.580.10 131 297 1.3E-15 T 22-04-2016 HRM2_RS18895 76d67841f9800f1d04cac6e0e8ae77c2 304 PANTHER PTHR26402 5 112 3.3E-32 T 22-04-2016 HRM2_RS18895 76d67841f9800f1d04cac6e0e8ae77c2 304 Gene3D G3DSA:3.40.50.2300 2 122 3.2E-34 T 22-04-2016 HRM2_RS18895 76d67841f9800f1d04cac6e0e8ae77c2 304 SUPERFAMILY SSF54631 126 300 2.4E-18 T 22-04-2016 HRM2_RS06260 123ace1d5094347e0abaf9902e94feff 146 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 146 46.26 T 22-04-2016 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 HRM2_RS06260 123ace1d5094347e0abaf9902e94feff 146 Pfam PF02381 MraZ protein, putative antitoxin-like 73 137 9.0E-17 T 22-04-2016 IPR020603 MraZ domain HRM2_RS06260 123ace1d5094347e0abaf9902e94feff 146 Pfam PF02381 MraZ protein, putative antitoxin-like 1 70 6.4E-11 T 22-04-2016 IPR020603 MraZ domain HRM2_RS06260 123ace1d5094347e0abaf9902e94feff 146 SUPERFAMILY SSF89447 1 132 6.06E-39 T 22-04-2016 HRM2_RS06260 123ace1d5094347e0abaf9902e94feff 146 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 142 9.2E-38 T 22-04-2016 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 HRM2_RS06260 123ace1d5094347e0abaf9902e94feff 146 PANTHER PTHR34701 2 145 2.0E-44 T 22-04-2016 HRM2_RS06260 123ace1d5094347e0abaf9902e94feff 146 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 122 2.0E-25 T 22-04-2016 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 HRM2_RS20095 4520b3a853ff5560f17e955d0970eee8 53 PRINTS PR00163 Rubredoxin signature 3 19 7.1E-13 T 22-04-2016 IPR024935 Rubredoxin domain GO:0005506 HRM2_RS20095 4520b3a853ff5560f17e955d0970eee8 53 PRINTS PR00163 Rubredoxin signature 33 49 7.1E-13 T 22-04-2016 IPR024935 Rubredoxin domain GO:0005506 HRM2_RS20095 4520b3a853ff5560f17e955d0970eee8 53 PIRSF PIRSF000071 1 53 9.3E-29 T 22-04-2016 IPR024922 Rubredoxin GO:0005506|GO:0009055 HRM2_RS20095 4520b3a853ff5560f17e955d0970eee8 53 Pfam PF00301 Rubredoxin 3 49 2.4E-25 T 22-04-2016 IPR024935 Rubredoxin domain GO:0005506 HRM2_RS20095 4520b3a853ff5560f17e955d0970eee8 53 Gene3D G3DSA:2.20.28.10 1 51 2.3E-28 T 22-04-2016 IPR004039 Rubredoxin-type fold HRM2_RS20095 4520b3a853ff5560f17e955d0970eee8 53 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 22-04-2016 IPR018527 Rubredoxin, iron-binding site GO:0046872 HRM2_RS20095 4520b3a853ff5560f17e955d0970eee8 53 SUPERFAMILY SSF57802 1 51 4.38E-23 T 22-04-2016 HRM2_RS21810 e107f391fe1758a178237a0e98593008 87 Pfam PF06742 Protein of unknown function (DUF1214) 2 71 2.7E-9 T 22-04-2016 IPR010621 Domain of unknown function DUF1214 HRM2_RS21810 e107f391fe1758a178237a0e98593008 87 Gene3D G3DSA:2.60.120.600 1 85 4.4E-18 T 22-04-2016 IPR010621 Domain of unknown function DUF1214 HRM2_RS21810 e107f391fe1758a178237a0e98593008 87 SUPERFAMILY SSF160935 1 84 9.15E-23 T 22-04-2016 HRM2_RS15795 85e4d9301dcf8d11b11bfc0d96dea520 418 SUPERFAMILY SSF47384 162 207 8.83E-5 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS15795 85e4d9301dcf8d11b11bfc0d96dea520 418 PANTHER PTHR24423 216 415 1.8E-50 T 22-04-2016 HRM2_RS15795 85e4d9301dcf8d11b11bfc0d96dea520 418 PANTHER PTHR24423 164 196 1.8E-50 T 22-04-2016 HRM2_RS15795 85e4d9301dcf8d11b11bfc0d96dea520 418 PANTHER PTHR24423 126 147 1.8E-50 T 22-04-2016 HRM2_RS15795 85e4d9301dcf8d11b11bfc0d96dea520 418 SUPERFAMILY SSF52172 6 152 1.11E-40 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS15795 85e4d9301dcf8d11b11bfc0d96dea520 418 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 300 408 4.7E-20 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS15795 85e4d9301dcf8d11b11bfc0d96dea520 418 SMART SM00387 294 410 2.2E-19 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS15795 85e4d9301dcf8d11b11bfc0d96dea520 418 SMART SM00448 7 119 2.3E-34 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS15795 85e4d9301dcf8d11b11bfc0d96dea520 418 PANTHER PTHR24423:SF445 216 415 1.8E-50 T 22-04-2016 HRM2_RS15795 85e4d9301dcf8d11b11bfc0d96dea520 418 PANTHER PTHR24423:SF445 164 196 1.8E-50 T 22-04-2016 HRM2_RS15795 85e4d9301dcf8d11b11bfc0d96dea520 418 PANTHER PTHR24423:SF445 126 147 1.8E-50 T 22-04-2016 HRM2_RS15795 85e4d9301dcf8d11b11bfc0d96dea520 418 Gene3D G3DSA:3.40.50.2300 6 148 1.0E-37 T 22-04-2016 HRM2_RS15795 85e4d9301dcf8d11b11bfc0d96dea520 418 SUPERFAMILY SSF55874 244 410 6.94E-31 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS15795 85e4d9301dcf8d11b11bfc0d96dea520 418 Pfam PF00072 Response regulator receiver domain 9 113 1.3E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS15795 85e4d9301dcf8d11b11bfc0d96dea520 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 366 1.6E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS15795 85e4d9301dcf8d11b11bfc0d96dea520 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 407 1.6E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS15795 85e4d9301dcf8d11b11bfc0d96dea520 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 387 1.6E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS15795 85e4d9301dcf8d11b11bfc0d96dea520 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 338 352 1.6E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS15795 85e4d9301dcf8d11b11bfc0d96dea520 418 Gene3D G3DSA:3.30.565.10 256 408 2.8E-33 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS11955 09b522e10199ed1580cf8d25581d5323 235 Pfam PF04012 PspA/IM30 family 2 227 3.8E-40 T 22-04-2016 IPR007157 PspA/IM30 HRM2_RS11955 09b522e10199ed1580cf8d25581d5323 235 PANTHER PTHR31088 1 228 6.0E-30 T 22-04-2016 HRM2_RS13125 a7398508cf03c236a0aaf5d0f33b62fe 430 Pfam PF13432 Tetratricopeptide repeat 293 348 0.0033 T 22-04-2016 HRM2_RS13125 a7398508cf03c236a0aaf5d0f33b62fe 430 SUPERFAMILY SSF48452 188 349 4.0E-18 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS13125 a7398508cf03c236a0aaf5d0f33b62fe 430 PANTHER PTHR23083 176 418 1.4E-13 T 22-04-2016 HRM2_RS13125 a7398508cf03c236a0aaf5d0f33b62fe 430 Gene3D G3DSA:1.25.40.10 191 417 5.9E-22 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS13125 a7398508cf03c236a0aaf5d0f33b62fe 430 Gene3D G3DSA:1.25.40.10 68 113 5.9E-22 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS04745 4dfc896481841279b1df27d84bad299a 74 Gene3D G3DSA:1.20.1250.20 2 62 0.001 T 22-04-2016 HRM2_RS17615 f9ae1b07ec12f4ee776eb8a9b5b49f33 262 PANTHER PTHR21294 1 260 9.1E-78 T 22-04-2016 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 HRM2_RS17615 f9ae1b07ec12f4ee776eb8a9b5b49f33 262 SMART SM00893 24 214 7.9E-49 T 22-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 HRM2_RS17615 f9ae1b07ec12f4ee776eb8a9b5b49f33 262 SUPERFAMILY SSF52402 1 257 3.14E-67 T 22-04-2016 HRM2_RS17615 f9ae1b07ec12f4ee776eb8a9b5b49f33 262 PANTHER PTHR21294:SF0 1 260 9.1E-78 T 22-04-2016 HRM2_RS17615 f9ae1b07ec12f4ee776eb8a9b5b49f33 262 Pfam PF01012 Electron transfer flavoprotein domain 29 209 3.6E-46 T 22-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 HRM2_RS17615 f9ae1b07ec12f4ee776eb8a9b5b49f33 262 PIRSF PIRSF000090 1 262 2.4E-67 T 22-04-2016 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 HRM2_RS17615 f9ae1b07ec12f4ee776eb8a9b5b49f33 262 Gene3D G3DSA:3.40.50.620 1 259 1.6E-77 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS04620 0652f1ff43bba3b0517dc6e904c77194 99 SUPERFAMILY SSF143011 1 82 1.57E-16 T 22-04-2016 HRM2_RS04620 0652f1ff43bba3b0517dc6e904c77194 99 PANTHER PTHR40266:SF1 1 99 2.0E-35 T 22-04-2016 HRM2_RS04620 0652f1ff43bba3b0517dc6e904c77194 99 PANTHER PTHR40266 1 99 2.0E-35 T 22-04-2016 HRM2_RS04620 0652f1ff43bba3b0517dc6e904c77194 99 Pfam PF05015 RelE-like toxin of type II toxin-antitoxin system HigB 4 95 5.6E-34 T 22-04-2016 IPR007711 Toxin HigB-1 HRM2_RS20060 fa629b2aa2975d7637c388022769fafe 159 Gene3D G3DSA:1.25.10.10 28 137 2.7E-6 T 22-04-2016 IPR011989 Armadillo-like helical HRM2_RS20060 fa629b2aa2975d7637c388022769fafe 159 SUPERFAMILY SSF48371 20 146 4.22E-7 T 22-04-2016 IPR016024 Armadillo-type fold GO:0005488 HRM2_RS09520 5a3b86a677b70f62b209687d86d46be4 392 SUPERFAMILY SSF52200 143 261 1.44E-12 T 22-04-2016 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 HRM2_RS09520 5a3b86a677b70f62b209687d86d46be4 392 Gene3D G3DSA:3.40.50.10140 147 242 9.9E-9 T 22-04-2016 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 HRM2_RS09520 5a3b86a677b70f62b209687d86d46be4 392 Pfam PF13676 TIR domain 148 237 2.0E-10 T 22-04-2016 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 HRM2_RS09520 5a3b86a677b70f62b209687d86d46be4 392 SMART SM00255 145 282 0.0046 T 22-04-2016 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 HRM2_RS08445 25ab50749cf2dec91e03f3673bba5f84 392 PANTHER PTHR34184:SF4 16 344 9.0E-77 T 22-04-2016 HRM2_RS08445 25ab50749cf2dec91e03f3673bba5f84 392 Pfam PF03773 Predicted permease 16 334 7.1E-43 T 22-04-2016 IPR005524 Predicted permease DUF318 HRM2_RS08445 25ab50749cf2dec91e03f3673bba5f84 392 PANTHER PTHR34184 16 344 9.0E-77 T 22-04-2016 HRM2_RS09125 901554084243b93b3c4b78dee3e9d946 541 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 67 222 3.2E-14 T 22-04-2016 HRM2_RS09125 901554084243b93b3c4b78dee3e9d946 541 PANTHER PTHR33908 13 372 1.3E-55 T 22-04-2016 HRM2_RS09125 901554084243b93b3c4b78dee3e9d946 541 PANTHER PTHR33908:SF3 13 372 1.3E-55 T 22-04-2016 HRM2_RS14650 264b35ff1ad960cad9e1a8a99cae7df1 481 SMART SM00387 363 475 2.0E-28 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS14650 264b35ff1ad960cad9e1a8a99cae7df1 481 Pfam PF00672 HAMP domain 181 247 4.3E-13 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS14650 264b35ff1ad960cad9e1a8a99cae7df1 481 SMART SM00388 252 318 4.4E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS14650 264b35ff1ad960cad9e1a8a99cae7df1 481 SMART SM00304 200 251 1.3E-8 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS14650 264b35ff1ad960cad9e1a8a99cae7df1 481 Gene3D G3DSA:3.30.565.10 320 475 1.2E-39 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS14650 264b35ff1ad960cad9e1a8a99cae7df1 481 SUPERFAMILY SSF158472 200 248 2.22E-8 T 22-04-2016 HRM2_RS14650 264b35ff1ad960cad9e1a8a99cae7df1 481 SUPERFAMILY SSF55874 309 473 6.94E-42 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS14650 264b35ff1ad960cad9e1a8a99cae7df1 481 Pfam PF00512 His Kinase A (phospho-acceptor) domain 253 318 1.2E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS14650 264b35ff1ad960cad9e1a8a99cae7df1 481 SUPERFAMILY SSF47384 235 318 4.32E-13 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS14650 264b35ff1ad960cad9e1a8a99cae7df1 481 PANTHER PTHR24423 194 476 7.0E-66 T 22-04-2016 HRM2_RS14650 264b35ff1ad960cad9e1a8a99cae7df1 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 472 3.4E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS14650 264b35ff1ad960cad9e1a8a99cae7df1 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 453 3.4E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS14650 264b35ff1ad960cad9e1a8a99cae7df1 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 414 3.4E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS14650 264b35ff1ad960cad9e1a8a99cae7df1 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 428 3.4E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS14650 264b35ff1ad960cad9e1a8a99cae7df1 481 Gene3D G3DSA:1.10.287.130 242 314 3.6E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS14650 264b35ff1ad960cad9e1a8a99cae7df1 481 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 366 474 2.8E-23 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS14635 6db23ab347487c2f1562e69cbf3f4023 243 Gene3D G3DSA:1.10.3720.10 40 229 2.6E-30 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS14635 6db23ab347487c2f1562e69cbf3f4023 243 PANTHER PTHR30177 1 240 6.3E-61 T 22-04-2016 HRM2_RS14635 6db23ab347487c2f1562e69cbf3f4023 243 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 64 230 1.1E-23 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS14635 6db23ab347487c2f1562e69cbf3f4023 243 SUPERFAMILY SSF161098 40 226 3.27E-39 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS11120 eb04e51ad2149ada0a7179050297621f 261 Gene3D G3DSA:2.160.10.10 4 191 6.3E-50 T 22-04-2016 HRM2_RS11120 eb04e51ad2149ada0a7179050297621f 261 SUPERFAMILY SSF51161 4 261 1.89E-76 T 22-04-2016 IPR011004 Trimeric LpxA-like HRM2_RS11120 eb04e51ad2149ada0a7179050297621f 261 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 179 259 1.1E-27 T 22-04-2016 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12|UniPathway: UPA00359 HRM2_RS11120 eb04e51ad2149ada0a7179050297621f 261 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 108 142 1.4E-4 T 22-04-2016 IPR001451 Hexapeptide repeat HRM2_RS11120 eb04e51ad2149ada0a7179050297621f 261 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 17 49 4.6E-7 T 22-04-2016 IPR001451 Hexapeptide repeat HRM2_RS11120 eb04e51ad2149ada0a7179050297621f 261 PANTHER PTHR23416 6 253 2.3E-117 T 22-04-2016 HRM2_RS11120 eb04e51ad2149ada0a7179050297621f 261 PIRSF PIRSF000456 4 261 1.7E-105 T 22-04-2016 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12|UniPathway: UPA00359 HRM2_RS11120 eb04e51ad2149ada0a7179050297621f 261 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 152 180 - T 22-04-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 HRM2_RS11120 eb04e51ad2149ada0a7179050297621f 261 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 134 162 - T 22-04-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 HRM2_RS11120 eb04e51ad2149ada0a7179050297621f 261 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 25 53 - T 22-04-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 HRM2_RS11120 eb04e51ad2149ada0a7179050297621f 261 PANTHER PTHR23416:SF8 6 253 2.3E-117 T 22-04-2016 HRM2_RS11120 eb04e51ad2149ada0a7179050297621f 261 Gene3D G3DSA:1.20.1180.10 196 261 4.6E-21 T 22-04-2016 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12|UniPathway: UPA00359 HRM2_RS11120 eb04e51ad2149ada0a7179050297621f 261 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 4 261 43.983 T 22-04-2016 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12|UniPathway: UPA00359 HRM2_RS11120 eb04e51ad2149ada0a7179050297621f 261 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 7 259 2.1E-101 T 22-04-2016 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12|UniPathway: UPA00359 HRM2_RS22480 49cc34f31ae780491fad36854c422b81 286 PANTHER PTHR30477:SF1 11 276 1.1E-65 T 22-04-2016 HRM2_RS22480 49cc34f31ae780491fad36854c422b81 286 PRINTS PR00691 Adhesin B signature 72 91 6.97E-5 T 22-04-2016 IPR006129 Adhesin B GO:0007155 HRM2_RS22480 49cc34f31ae780491fad36854c422b81 286 PRINTS PR00691 Adhesin B signature 28 49 6.97E-5 T 22-04-2016 IPR006129 Adhesin B GO:0007155 HRM2_RS22480 49cc34f31ae780491fad36854c422b81 286 PRINTS PR00691 Adhesin B signature 225 242 6.97E-5 T 22-04-2016 IPR006129 Adhesin B GO:0007155 HRM2_RS22480 49cc34f31ae780491fad36854c422b81 286 PRINTS PR00691 Adhesin B signature 53 71 6.97E-5 T 22-04-2016 IPR006129 Adhesin B GO:0007155 HRM2_RS22480 49cc34f31ae780491fad36854c422b81 286 Pfam PF01297 Zinc-uptake complex component A periplasmic 31 279 1.1E-55 T 22-04-2016 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 HRM2_RS22480 49cc34f31ae780491fad36854c422b81 286 PRINTS PR00690 Adhesin family signature 229 247 8.86E-5 T 22-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 HRM2_RS22480 49cc34f31ae780491fad36854c422b81 286 PRINTS PR00690 Adhesin family signature 59 72 8.86E-5 T 22-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 HRM2_RS22480 49cc34f31ae780491fad36854c422b81 286 PRINTS PR00690 Adhesin family signature 178 199 8.86E-5 T 22-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 HRM2_RS22480 49cc34f31ae780491fad36854c422b81 286 PRINTS PR00690 Adhesin family signature 72 89 8.86E-5 T 22-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 HRM2_RS22480 49cc34f31ae780491fad36854c422b81 286 Gene3D G3DSA:3.40.50.1980 179 281 1.6E-26 T 22-04-2016 HRM2_RS22480 49cc34f31ae780491fad36854c422b81 286 SUPERFAMILY SSF53807 28 280 3.34E-70 T 22-04-2016 HRM2_RS22480 49cc34f31ae780491fad36854c422b81 286 Gene3D G3DSA:3.40.50.1980 29 178 3.8E-39 T 22-04-2016 HRM2_RS22480 49cc34f31ae780491fad36854c422b81 286 PANTHER PTHR30477 11 276 1.1E-65 T 22-04-2016 HRM2_RS19255 8a68db9df32449a2adf0259143b49f32 132 Pfam PF00271 Helicase conserved C-terminal domain 1 37 1.1E-11 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS19255 8a68db9df32449a2adf0259143b49f32 132 Gene3D G3DSA:3.40.50.300 1 63 6.8E-22 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19255 8a68db9df32449a2adf0259143b49f32 132 Pfam PF03880 DbpA RNA binding domain 87 126 5.4E-9 T 22-04-2016 IPR005580 DbpA, RNA-binding domain HRM2_RS19255 8a68db9df32449a2adf0259143b49f32 132 SUPERFAMILY SSF52540 1 82 7.89E-20 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19255 8a68db9df32449a2adf0259143b49f32 132 PANTHER PTHR24031 1 121 3.5E-38 T 22-04-2016 HRM2_RS19255 8a68db9df32449a2adf0259143b49f32 132 PANTHER PTHR24031:SF180 1 121 3.5E-38 T 22-04-2016 HRM2_RS02020 303e644ef34d729572e046e3de3408f3 248 Pfam PF04016 Putative heavy-metal chelation 135 231 3.9E-11 T 22-04-2016 IPR007161 Putative heavy-metal chelation domain HRM2_RS02020 303e644ef34d729572e046e3de3408f3 248 SUPERFAMILY SSF159713 78 231 4.84E-15 T 22-04-2016 HRM2_RS08225 f1bc595f270b3e382b38ad0b1ffe726c 143 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 47 138 1.4E-7 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS08225 f1bc595f270b3e382b38ad0b1ffe726c 143 Gene3D G3DSA:3.30.565.10 56 138 4.0E-14 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS08225 f1bc595f270b3e382b38ad0b1ffe726c 143 SUPERFAMILY SSF55874 39 137 4.79E-12 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS08015 7407e9a82f06f77d30f34114daf45bbc 633 PANTHER PTHR33362:SF1 1 630 7.0E-191 T 22-04-2016 HRM2_RS08015 7407e9a82f06f77d30f34114daf45bbc 633 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 30 628 6.6E-192 T 22-04-2016 IPR011853 TRAP transporter, 4TM/12TM fusion protein HRM2_RS08015 7407e9a82f06f77d30f34114daf45bbc 633 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 125 552 3.4E-79 T 22-04-2016 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit HRM2_RS08015 7407e9a82f06f77d30f34114daf45bbc 633 PANTHER PTHR33362 1 630 7.0E-191 T 22-04-2016 HRM2_RS20490 a32b88d6286e59c6e8ed4b5f3488ab7a 136 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 4 84 6.3E-15 T 22-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 HRM2_RS20490 a32b88d6286e59c6e8ed4b5f3488ab7a 136 Gene3D G3DSA:2.30.110.10 1 123 9.1E-29 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 HRM2_RS20490 a32b88d6286e59c6e8ed4b5f3488ab7a 136 PANTHER PTHR40660 1 136 5.8E-30 T 22-04-2016 HRM2_RS20490 a32b88d6286e59c6e8ed4b5f3488ab7a 136 SUPERFAMILY SSF50475 1 134 5.66E-25 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 HRM2_RS13890 635f18c8476016189aabea998844e199 495 SUPERFAMILY SSF55874 386 484 2.36E-17 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS13890 635f18c8476016189aabea998844e199 495 SMART SM00387 393 489 0.001 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS13890 635f18c8476016189aabea998844e199 495 Gene3D G3DSA:3.30.565.10 384 487 1.8E-11 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS13890 635f18c8476016189aabea998844e199 495 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 398 483 1.6E-7 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS13890 635f18c8476016189aabea998844e199 495 PANTHER PTHR24423 268 487 1.2E-36 T 22-04-2016 HRM2_RS13890 635f18c8476016189aabea998844e199 495 PANTHER PTHR24423 136 152 1.2E-36 T 22-04-2016 HRM2_RS13890 635f18c8476016189aabea998844e199 495 Pfam PF07730 Histidine kinase 290 352 1.2E-5 T 22-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 HRM2_RS13890 635f18c8476016189aabea998844e199 495 PRINTS PR00344 Bacterial sensor protein C-terminal signature 473 486 2.7E-5 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS13890 635f18c8476016189aabea998844e199 495 PRINTS PR00344 Bacterial sensor protein C-terminal signature 449 467 2.7E-5 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS13890 635f18c8476016189aabea998844e199 495 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 443 2.7E-5 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS13890 635f18c8476016189aabea998844e199 495 PANTHER PTHR24423:SF549 268 487 1.2E-36 T 22-04-2016 HRM2_RS13890 635f18c8476016189aabea998844e199 495 PANTHER PTHR24423:SF549 136 152 1.2E-36 T 22-04-2016 HRM2_RS03830 6811172d50009e6428b127012d1a542e 456 Gene3D G3DSA:3.40.630.10 14 207 1.5E-22 T 22-04-2016 HRM2_RS03830 6811172d50009e6428b127012d1a542e 456 Gene3D G3DSA:3.40.630.10 248 327 1.5E-22 T 22-04-2016 HRM2_RS03830 6811172d50009e6428b127012d1a542e 456 SUPERFAMILY SSF53187 337 433 3.14E-20 T 22-04-2016 HRM2_RS03830 6811172d50009e6428b127012d1a542e 456 SUPERFAMILY SSF53187 14 200 3.14E-20 T 22-04-2016 HRM2_RS03830 6811172d50009e6428b127012d1a542e 456 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 78 87 - T 22-04-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 HRM2_RS03830 6811172d50009e6428b127012d1a542e 456 Pfam PF01546 Peptidase family M20/M25/M40 80 431 6.4E-15 T 22-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 HRM2_RS08455 e8fcd4b27020d1979855dcd9c05fa9a2 238 PANTHER PTHR10108:SF752 1 181 2.6E-20 T 22-04-2016 HRM2_RS08455 e8fcd4b27020d1979855dcd9c05fa9a2 238 PANTHER PTHR10108 1 181 2.6E-20 T 22-04-2016 HRM2_RS08455 e8fcd4b27020d1979855dcd9c05fa9a2 238 Pfam PF08241 Methyltransferase domain 18 119 9.0E-20 T 22-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 HRM2_RS08455 e8fcd4b27020d1979855dcd9c05fa9a2 238 Gene3D G3DSA:3.40.50.150 7 235 1.1E-36 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS08455 e8fcd4b27020d1979855dcd9c05fa9a2 238 SUPERFAMILY SSF53335 9 203 3.28E-31 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS23885 6bb8fb3e38954f3e7a968175f76090f4 234 PANTHER PTHR31272 25 229 2.7E-24 T 22-04-2016 HRM2_RS23885 6bb8fb3e38954f3e7a968175f76090f4 234 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 25 228 6.8E-16 T 22-04-2016 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 HRM2_RS23885 6bb8fb3e38954f3e7a968175f76090f4 234 PANTHER PTHR31272:SF1 25 229 2.7E-24 T 22-04-2016 HRM2_RS18805 552e0ce8780b5ab5befb62a369b5e712 309 SUPERFAMILY SSF53613 27 303 7.27E-49 T 22-04-2016 IPR029056 Ribokinase-like HRM2_RS18805 552e0ce8780b5ab5befb62a369b5e712 309 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 40 47 1.1E-26 T 22-04-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 HRM2_RS18805 552e0ce8780b5ab5befb62a369b5e712 309 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 110 127 1.1E-26 T 22-04-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 HRM2_RS18805 552e0ce8780b5ab5befb62a369b5e712 309 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 53 74 1.1E-26 T 22-04-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 HRM2_RS18805 552e0ce8780b5ab5befb62a369b5e712 309 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 141 155 1.1E-26 T 22-04-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 HRM2_RS18805 552e0ce8780b5ab5befb62a369b5e712 309 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 84 92 1.1E-26 T 22-04-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 HRM2_RS18805 552e0ce8780b5ab5befb62a369b5e712 309 Gene3D G3DSA:3.40.1190.20 23 306 7.8E-76 T 22-04-2016 IPR029056 Ribokinase-like HRM2_RS18805 552e0ce8780b5ab5befb62a369b5e712 309 PANTHER PTHR20857 204 307 1.7E-60 T 22-04-2016 HRM2_RS18805 552e0ce8780b5ab5befb62a369b5e712 309 PANTHER PTHR20857 28 184 1.7E-60 T 22-04-2016 HRM2_RS18805 552e0ce8780b5ab5befb62a369b5e712 309 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 34 299 28.549 T 22-04-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 HRM2_RS18805 552e0ce8780b5ab5befb62a369b5e712 309 PANTHER PTHR20857:SF19 204 307 1.7E-60 T 22-04-2016 HRM2_RS18805 552e0ce8780b5ab5befb62a369b5e712 309 PANTHER PTHR20857:SF19 28 184 1.7E-60 T 22-04-2016 HRM2_RS18805 552e0ce8780b5ab5befb62a369b5e712 309 Pfam PF02110 Hydroxyethylthiazole kinase family 205 295 2.4E-19 T 22-04-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 HRM2_RS18805 552e0ce8780b5ab5befb62a369b5e712 309 Pfam PF02110 Hydroxyethylthiazole kinase family 34 166 1.4E-40 T 22-04-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 HRM2_RS24020 6e793a0770590c7d6d357497589a34f9 178 PANTHER PTHR33741 14 178 3.3E-49 T 22-04-2016 HRM2_RS24020 6e793a0770590c7d6d357497589a34f9 178 PANTHER PTHR33741:SF1 14 178 3.3E-49 T 22-04-2016 HRM2_RS24020 6e793a0770590c7d6d357497589a34f9 178 Pfam PF04982 HPP family 52 174 2.5E-45 T 22-04-2016 IPR007065 HPP HRM2_RS09295 5bff55e5e7ba7a9c9e11e8f69918539b 155 SUPERFAMILY SSF54995 1 98 3.14E-30 T 22-04-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 HRM2_RS09295 5bff55e5e7ba7a9c9e11e8f69918539b 155 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 1.9E-20 T 22-04-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 HRM2_RS09295 5bff55e5e7ba7a9c9e11e8f69918539b 155 Gene3D G3DSA:3.30.70.60 1 98 8.7E-32 T 22-04-2016 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 HRM2_RS09295 5bff55e5e7ba7a9c9e11e8f69918539b 155 PANTHER PTHR21011 1 136 6.1E-25 T 22-04-2016 HRM2_RS09295 5bff55e5e7ba7a9c9e11e8f69918539b 155 Pfam PF01250 Ribosomal protein S6 4 91 8.6E-27 T 22-04-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 HRM2_RS09295 5bff55e5e7ba7a9c9e11e8f69918539b 155 PANTHER PTHR21011:SF1 1 136 6.1E-25 T 22-04-2016 HRM2_RS09295 5bff55e5e7ba7a9c9e11e8f69918539b 155 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 20.036 T 22-04-2016 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 HRM2_RS14710 3e1cb46ebfea9296ba873e3050008cc6 331 PANTHER PTHR10366 3 263 4.6E-72 T 22-04-2016 HRM2_RS14710 3e1cb46ebfea9296ba873e3050008cc6 331 PANTHER PTHR10366 287 331 4.6E-72 T 22-04-2016 HRM2_RS14710 3e1cb46ebfea9296ba873e3050008cc6 331 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 232 5.0E-41 T 22-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 HRM2_RS14710 3e1cb46ebfea9296ba873e3050008cc6 331 SUPERFAMILY SSF51735 3 328 8.9E-69 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS14710 3e1cb46ebfea9296ba873e3050008cc6 331 Gene3D G3DSA:3.40.50.720 3 323 2.7E-59 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS05655 86ec1f302da01433bb66ab4be2c89a8d 184 Gene3D G3DSA:3.40.50.2020 2 179 1.3E-44 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like HRM2_RS05655 86ec1f302da01433bb66ab4be2c89a8d 184 SUPERFAMILY SSF53271 19 179 4.46E-33 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like HRM2_RS05655 86ec1f302da01433bb66ab4be2c89a8d 184 PANTHER PTHR19278 1 181 6.4E-50 T 22-04-2016 HRM2_RS05655 86ec1f302da01433bb66ab4be2c89a8d 184 Pfam PF00156 Phosphoribosyl transferase domain 77 161 4.1E-9 T 22-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 HRM2_RS05655 86ec1f302da01433bb66ab4be2c89a8d 184 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 184 24.499 T 22-04-2016 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|UniPathway: UPA00070 HRM2_RS05655 86ec1f302da01433bb66ab4be2c89a8d 184 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 18 174 6.6E-38 T 22-04-2016 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|UniPathway: UPA00070 HRM2_RS03470 a1f2e63144fec8c570bc2390c35b914b 141 Pfam PF00072 Response regulator receiver domain 7 116 2.3E-27 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS03470 a1f2e63144fec8c570bc2390c35b914b 141 PANTHER PTHR26402 5 116 7.0E-30 T 22-04-2016 HRM2_RS03470 a1f2e63144fec8c570bc2390c35b914b 141 Gene3D G3DSA:3.40.50.2300 3 121 9.8E-33 T 22-04-2016 HRM2_RS03470 a1f2e63144fec8c570bc2390c35b914b 141 SMART SM00448 5 116 5.6E-27 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS03470 a1f2e63144fec8c570bc2390c35b914b 141 SUPERFAMILY SSF52172 3 121 2.56E-34 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS23095 9afdc1be658a6dd1cc5652798192b2e6 321 Pfam PF02653 Branched-chain amino acid transport system / permease component 34 298 1.0E-37 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 HRM2_RS23095 9afdc1be658a6dd1cc5652798192b2e6 321 PANTHER PTHR30482:SF7 18 320 4.2E-91 T 22-04-2016 HRM2_RS23095 9afdc1be658a6dd1cc5652798192b2e6 321 PANTHER PTHR30482 18 320 4.2E-91 T 22-04-2016 HRM2_RS18105 c03804c92ed3d2c6ca8b59eb83ec0df5 298 PANTHER PTHR30433 15 279 8.6E-56 T 22-04-2016 HRM2_RS18105 c03804c92ed3d2c6ca8b59eb83ec0df5 298 Pfam PF01618 MotA/TolQ/ExbB proton channel family 130 225 8.4E-14 T 22-04-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 HRM2_RS14345 8a48f0ed5d6aea83131ceeab7cae2f44 237 SUPERFAMILY SSF48008 83 218 2.62E-21 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS14345 8a48f0ed5d6aea83131ceeab7cae2f44 237 SMART SM00895 87 211 7.0E-6 T 22-04-2016 IPR011711 GntR, C-terminal HRM2_RS14345 8a48f0ed5d6aea83131ceeab7cae2f44 237 SUPERFAMILY SSF46785 12 81 2.73E-14 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS14345 8a48f0ed5d6aea83131ceeab7cae2f44 237 Gene3D G3DSA:1.10.10.10 3 78 6.4E-15 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS14345 8a48f0ed5d6aea83131ceeab7cae2f44 237 Pfam PF07729 FCD domain 87 210 1.3E-12 T 22-04-2016 IPR011711 GntR, C-terminal HRM2_RS14345 8a48f0ed5d6aea83131ceeab7cae2f44 237 SMART SM00345 19 77 1.3E-4 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS14345 8a48f0ed5d6aea83131ceeab7cae2f44 237 Gene3D G3DSA:1.20.120.530 81 221 7.3E-20 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS14345 8a48f0ed5d6aea83131ceeab7cae2f44 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 77 3.3E-8 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS16865 5858c38936b9d9b074b953ea29af736d 253 Pfam PF00005 ABC transporter 26 170 6.4E-28 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS16865 5858c38936b9d9b074b953ea29af736d 253 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS16865 5858c38936b9d9b074b953ea29af736d 253 SMART SM00382 33 218 3.2E-14 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS16865 5858c38936b9d9b074b953ea29af736d 253 PANTHER PTHR24220:SF581 10 244 1.5E-99 T 22-04-2016 HRM2_RS16865 5858c38936b9d9b074b953ea29af736d 253 PANTHER PTHR24220 10 244 1.5E-99 T 22-04-2016 HRM2_RS16865 5858c38936b9d9b074b953ea29af736d 253 SUPERFAMILY SSF52540 8 229 3.93E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16865 5858c38936b9d9b074b953ea29af736d 253 Gene3D G3DSA:3.40.50.300 4 235 1.3E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03785 7cb1faecab0e0e2f1b11212768090d9e 530 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 8 25 - T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS03785 7cb1faecab0e0e2f1b11212768090d9e 530 PANTHER PTHR11985:SF14 1 514 4.0E-156 T 22-04-2016 HRM2_RS03785 7cb1faecab0e0e2f1b11212768090d9e 530 Gene3D G3DSA:3.50.50.60 1 239 4.9E-35 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS03785 7cb1faecab0e0e2f1b11212768090d9e 530 PANTHER PTHR11985 1 514 4.0E-156 T 22-04-2016 HRM2_RS03785 7cb1faecab0e0e2f1b11212768090d9e 530 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 76 88 7.0E-20 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS03785 7cb1faecab0e0e2f1b11212768090d9e 530 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 3 15 7.0E-20 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS03785 7cb1faecab0e0e2f1b11212768090d9e 530 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 16 26 7.0E-20 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS03785 7cb1faecab0e0e2f1b11212768090d9e 530 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 337 349 7.0E-20 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS03785 7cb1faecab0e0e2f1b11212768090d9e 530 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 303 309 7.0E-20 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS03785 7cb1faecab0e0e2f1b11212768090d9e 530 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 32 44 7.0E-20 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 HRM2_RS03785 7cb1faecab0e0e2f1b11212768090d9e 530 SUPERFAMILY SSF51905 3 220 8.48E-36 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS03785 7cb1faecab0e0e2f1b11212768090d9e 530 SUPERFAMILY SSF51905 322 363 8.48E-36 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS03785 7cb1faecab0e0e2f1b11212768090d9e 530 Pfam PF01266 FAD dependent oxidoreductase 5 355 4.5E-41 T 22-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 HRM2_RS03785 7cb1faecab0e0e2f1b11212768090d9e 530 SUPERFAMILY SSF54373 224 309 6.28E-7 T 22-04-2016 HRM2_RS09450 bd08d6b598d407ef9cc8097843b299d9 411 PANTHER PTHR30074 22 407 6.2E-15 T 22-04-2016 HRM2_RS09450 bd08d6b598d407ef9cc8097843b299d9 411 PANTHER PTHR30074:SF3 22 407 6.2E-15 T 22-04-2016 HRM2_RS09450 bd08d6b598d407ef9cc8097843b299d9 411 Pfam PF03916 Polysulphide reductase, NrfD 47 356 1.3E-10 T 22-04-2016 IPR005614 NrfD family HRM2_RS21620 eb62a2f6e0b5d8b3aa4341ea7c03462e 122 Gene3D G3DSA:3.30.70.20 3 75 4.2E-18 T 22-04-2016 HRM2_RS21620 eb62a2f6e0b5d8b3aa4341ea7c03462e 122 PANTHER PTHR24960:SF17 4 54 4.7E-14 T 22-04-2016 HRM2_RS21620 eb62a2f6e0b5d8b3aa4341ea7c03462e 122 PANTHER PTHR24960 4 54 4.7E-14 T 22-04-2016 HRM2_RS21620 eb62a2f6e0b5d8b3aa4341ea7c03462e 122 SUPERFAMILY SSF54862 1 58 4.37E-21 T 22-04-2016 HRM2_RS21620 eb62a2f6e0b5d8b3aa4341ea7c03462e 122 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 38 49 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS21620 eb62a2f6e0b5d8b3aa4341ea7c03462e 122 Pfam PF00037 4Fe-4S binding domain 2 25 5.0E-6 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS21620 eb62a2f6e0b5d8b3aa4341ea7c03462e 122 Pfam PF00037 4Fe-4S binding domain 32 53 2.5E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS07350 607e38cc98020dac0b2013c2ccc85273 73 Pfam PF09954 Uncharacterized protein conserved in bacteria (DUF2188) 5 64 2.3E-25 T 22-04-2016 IPR018691 Protein of unknown function DUF2188 HRM2_RS13335 fcbfdc588448202eeffe074c490d07cc 175 PANTHER PTHR34295:SF1 6 175 1.8E-54 T 22-04-2016 HRM2_RS13335 fcbfdc588448202eeffe074c490d07cc 175 PANTHER PTHR34295 6 175 1.8E-54 T 22-04-2016 HRM2_RS13335 fcbfdc588448202eeffe074c490d07cc 175 PIRSF PIRSF016661 1 175 3.6E-50 T 22-04-2016 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 HRM2_RS13335 fcbfdc588448202eeffe074c490d07cc 175 Pfam PF02632 BioY family 31 171 8.1E-44 T 22-04-2016 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 HRM2_RS18375 464b9cef5952611f5485464601210888 206 SUPERFAMILY SSF158791 141 202 2.09E-7 T 22-04-2016 HRM2_RS18375 464b9cef5952611f5485464601210888 206 Gene3D G3DSA:1.25.60.10 142 198 2.1E-4 T 22-04-2016 HRM2_RS03065 f6b099fac2d1c2e861a0b632529343ba 149 SUPERFAMILY SSF51206 3 125 2.62E-21 T 22-04-2016 IPR018490 Cyclic nucleotide-binding-like HRM2_RS03065 f6b099fac2d1c2e861a0b632529343ba 149 Gene3D G3DSA:2.60.120.10 6 126 3.2E-18 T 22-04-2016 IPR014710 RmlC-like jelly roll fold HRM2_RS03065 f6b099fac2d1c2e861a0b632529343ba 149 Pfam PF00027 Cyclic nucleotide-binding domain 34 115 4.2E-12 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain HRM2_RS03065 f6b099fac2d1c2e861a0b632529343ba 149 SMART SM00100 13 128 4.6E-8 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain HRM2_RS10785 fc9bfa5657e6bf995de30f277772dabe 457 PANTHER PTHR37560 1 457 4.7E-199 T 22-04-2016 HRM2_RS10785 fc9bfa5657e6bf995de30f277772dabe 457 PANTHER PTHR37560:SF1 1 457 4.7E-199 T 22-04-2016 HRM2_RS10785 fc9bfa5657e6bf995de30f277772dabe 457 Pfam PF05167 Uncharacterised ACR (DUF711) 13 420 2.2E-167 T 22-04-2016 IPR007841 Uncharacterised protein family UPF0210 HRM2_RS10785 fc9bfa5657e6bf995de30f277772dabe 457 Gene3D G3DSA:3.20.70.20 1 457 6.2E-188 T 22-04-2016 HRM2_RS10785 fc9bfa5657e6bf995de30f277772dabe 457 SUPERFAMILY SSF51998 3 452 1.01E-160 T 22-04-2016 HRM2_RS16765 11b56a4d8ee05ce049ba6745fdaafb1f 206 Pfam PF03006 Haemolysin-III related 3 196 1.3E-43 T 22-04-2016 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 HRM2_RS16765 11b56a4d8ee05ce049ba6745fdaafb1f 206 PANTHER PTHR20855:SF3 3 206 1.6E-68 T 22-04-2016 IPR005744 Hly-III GO:0016021|GO:0019835 HRM2_RS16765 11b56a4d8ee05ce049ba6745fdaafb1f 206 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 3 203 7.9E-68 T 22-04-2016 IPR005744 Hly-III GO:0016021|GO:0019835 HRM2_RS16765 11b56a4d8ee05ce049ba6745fdaafb1f 206 PANTHER PTHR20855 3 206 1.6E-68 T 22-04-2016 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 HRM2_RS04825 3616df911bba678b958ef31d475accde 197 PANTHER PTHR30086:SF0 1 197 1.9E-75 T 22-04-2016 HRM2_RS04825 3616df911bba678b958ef31d475accde 197 PANTHER PTHR30086 1 197 1.9E-75 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 HRM2_RS04825 3616df911bba678b958ef31d475accde 197 Pfam PF01810 LysE type translocator 14 197 6.6E-35 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 HRM2_RS18475 442c960a860d1d74face362d1d56d00b 277 PANTHER PTHR12553:SF29 1 249 4.5E-59 T 22-04-2016 HRM2_RS18475 442c960a860d1d74face362d1d56d00b 277 Gene3D G3DSA:3.60.15.10 3 256 3.0E-33 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS18475 442c960a860d1d74face362d1d56d00b 277 SMART SM00849 25 214 7.5E-5 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS18475 442c960a860d1d74face362d1d56d00b 277 Pfam PF12706 Beta-lactamase superfamily domain 39 236 1.9E-17 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS18475 442c960a860d1d74face362d1d56d00b 277 PANTHER PTHR12553 1 249 4.5E-59 T 22-04-2016 HRM2_RS18475 442c960a860d1d74face362d1d56d00b 277 SUPERFAMILY SSF56281 1 252 1.13E-36 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS01155 3ab17b8c50af794a88304a45da79bb14 399 SUPERFAMILY SSF111369 71 268 3.53E-17 T 22-04-2016 HRM2_RS01155 3ab17b8c50af794a88304a45da79bb14 399 Pfam PF13437 HlyD family secretion protein 198 304 1.1E-15 T 22-04-2016 HRM2_RS01155 3ab17b8c50af794a88304a45da79bb14 399 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 55 391 2.9E-31 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 HRM2_RS01155 3ab17b8c50af794a88304a45da79bb14 399 PANTHER PTHR30469 5 399 1.9E-28 T 22-04-2016 HRM2_RS01155 3ab17b8c50af794a88304a45da79bb14 399 Gene3D G3DSA:2.40.50.100 196 227 8.3E-9 T 22-04-2016 HRM2_RS01155 3ab17b8c50af794a88304a45da79bb14 399 Gene3D G3DSA:2.40.50.100 83 115 8.3E-9 T 22-04-2016 HRM2_RS22865 886427dc8cdfc7b2d92a30cf41f73501 330 Gene3D G3DSA:3.40.50.2300 131 286 2.4E-43 T 22-04-2016 HRM2_RS22865 886427dc8cdfc7b2d92a30cf41f73501 330 Pfam PF02608 Basic membrane protein 42 278 4.5E-36 T 22-04-2016 IPR003760 Basic membrane lipoprotein GO:0005886 HRM2_RS22865 886427dc8cdfc7b2d92a30cf41f73501 330 PANTHER PTHR34296 1 319 3.8E-52 T 22-04-2016 HRM2_RS10710 d7cdd7356e7666e4cdec408d7282dcbb 291 Pfam PF04321 RmlD substrate binding domain 1 282 2.1E-95 T 22-04-2016 IPR029903 RmlD-like substrate binding domain HRM2_RS10710 d7cdd7356e7666e4cdec408d7282dcbb 291 SUPERFAMILY SSF51735 1 281 4.83E-87 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS10710 d7cdd7356e7666e4cdec408d7282dcbb 291 Gene3D G3DSA:3.40.50.720 1 229 1.3E-58 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS10710 d7cdd7356e7666e4cdec408d7282dcbb 291 PANTHER PTHR10491 1 289 1.9E-96 T 22-04-2016 IPR005913 dTDP-4-dehydrorhamnose reductase family HRM2_RS10710 d7cdd7356e7666e4cdec408d7282dcbb 291 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 279 1.1E-92 T 22-04-2016 IPR005913 dTDP-4-dehydrorhamnose reductase family HRM2_RS04480 726b790bef13ff4d8acb7e4cc3561c89 549 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 17 500 3.7E-141 T 22-04-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 HRM2_RS04480 726b790bef13ff4d8acb7e4cc3561c89 549 ProSitePatterns PS01303 BCCT family of transporters signature. 316 325 - T 22-04-2016 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 HRM2_RS04480 726b790bef13ff4d8acb7e4cc3561c89 549 PANTHER PTHR30047 13 500 9.8E-134 T 22-04-2016 HRM2_RS04480 726b790bef13ff4d8acb7e4cc3561c89 549 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 54 501 1.7E-126 T 22-04-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 HRM2_RS19830 a56414491ef52409296a304d837362f4 160 Gene3D G3DSA:3.40.50.620 1 153 3.0E-35 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS19830 a56414491ef52409296a304d837362f4 160 SUPERFAMILY SSF52402 5 155 2.26E-33 T 22-04-2016 HRM2_RS19830 a56414491ef52409296a304d837362f4 160 PRINTS PR01438 Universal stress protein signature 111 123 1.8E-16 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS19830 a56414491ef52409296a304d837362f4 160 PRINTS PR01438 Universal stress protein signature 4 22 1.8E-16 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS19830 a56414491ef52409296a304d837362f4 160 PRINTS PR01438 Universal stress protein signature 129 151 1.8E-16 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS19830 a56414491ef52409296a304d837362f4 160 PIRSF PIRSF006276 1 154 1.7E-17 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS19830 a56414491ef52409296a304d837362f4 160 PANTHER PTHR31964 1 154 2.2E-26 T 22-04-2016 HRM2_RS19830 a56414491ef52409296a304d837362f4 160 Pfam PF00582 Universal stress protein family 4 151 1.9E-30 T 22-04-2016 IPR006016 UspA GO:0006950 HRM2_RS17690 01a9501819163a82a0188dc16488d3ae 260 PANTHER PTHR11079:SF60 14 256 1.2E-69 T 22-04-2016 HRM2_RS17690 01a9501819163a82a0188dc16488d3ae 260 Pfam PF00849 RNA pseudouridylate synthase 21 181 1.5E-34 T 22-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS17690 01a9501819163a82a0188dc16488d3ae 260 SUPERFAMILY SSF55120 12 251 3.2E-59 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HRM2_RS17690 01a9501819163a82a0188dc16488d3ae 260 PANTHER PTHR11079 14 256 1.2E-69 T 22-04-2016 HRM2_RS20910 3d24aee6334f96e8936ae9c8d16a32dc 273 Pfam PF03692 Putative zinc- or iron-chelating domain 29 129 8.3E-9 T 22-04-2016 IPR005358 Putative zinc- or iron-chelating domain containing protein HRM2_RS00275 c111f1daf7e1b42086c8e85cef5f6f92 254 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS00275 c111f1daf7e1b42086c8e85cef5f6f92 254 SUPERFAMILY SSF52540 20 228 6.71E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00275 c111f1daf7e1b42086c8e85cef5f6f92 254 PANTHER PTHR24220 3 224 7.0E-54 T 22-04-2016 HRM2_RS00275 c111f1daf7e1b42086c8e85cef5f6f92 254 SMART SM00382 36 218 2.3E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS00275 c111f1daf7e1b42086c8e85cef5f6f92 254 Gene3D G3DSA:3.40.50.300 5 226 5.8E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00275 c111f1daf7e1b42086c8e85cef5f6f92 254 Pfam PF00005 ABC transporter 28 168 2.8E-26 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS01255 27d5b4d42752b643c98fbff93bc916cd 88 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 5 80 9.5E-18 T 22-04-2016 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 HRM2_RS01255 27d5b4d42752b643c98fbff93bc916cd 88 SUPERFAMILY SSF55229 33 80 3.92E-9 T 22-04-2016 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 HRM2_RS01255 27d5b4d42752b643c98fbff93bc916cd 88 Pfam PF03776 Septum formation topological specificity factor MinE 15 80 1.1E-18 T 22-04-2016 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 HRM2_RS01255 27d5b4d42752b643c98fbff93bc916cd 88 Gene3D G3DSA:3.30.1070.10 34 85 5.4E-15 T 22-04-2016 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 HRM2_RS01255 27d5b4d42752b643c98fbff93bc916cd 88 Hamap MF_00262 Cell division topological specificity factor [minE]. 1 85 13.168 T 22-04-2016 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 HRM2_RS04305 ee69227962153af0e86ecf8e2d136e7e 218 Gene3D G3DSA:2.60.40.1190 19 217 1.6E-14 T 22-04-2016 IPR010502 Carbohydrate-binding domain, family 9 GO:0004553|GO:0016052|GO:0030246 MetaCyc: PWY-6784 HRM2_RS04305 ee69227962153af0e86ecf8e2d136e7e 218 Pfam PF16011 Carbohydrate-binding family 9 40 217 2.5E-44 T 22-04-2016 IPR010502 Carbohydrate-binding domain, family 9 GO:0004553|GO:0016052|GO:0030246 MetaCyc: PWY-6784 HRM2_RS04305 ee69227962153af0e86ecf8e2d136e7e 218 SUPERFAMILY SSF49344 17 217 2.63E-17 T 22-04-2016 HRM2_RS12970 41239ffaf6f7c31cd8c759104e9b6f6d 562 Gene3D G3DSA:3.30.420.10 153 298 3.5E-5 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS19695 41239ffaf6f7c31cd8c759104e9b6f6d 562 Gene3D G3DSA:3.30.420.10 153 298 3.5E-5 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS01720 52601646795dfe1a244adbdd0b9834ab 997 Gene3D G3DSA:3.30.1490.20 429 608 6.6E-20 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HRM2_RS01720 52601646795dfe1a244adbdd0b9834ab 997 Gene3D G3DSA:3.40.50.2300 67 121 5.1E-6 T 22-04-2016 HRM2_RS01720 52601646795dfe1a244adbdd0b9834ab 997 SUPERFAMILY SSF56059 435 668 1.29E-20 T 22-04-2016 HRM2_RS01720 52601646795dfe1a244adbdd0b9834ab 997 SUPERFAMILY SSF56059 756 806 1.29E-20 T 22-04-2016 HRM2_RS01720 52601646795dfe1a244adbdd0b9834ab 997 SUPERFAMILY SSF52172 69 130 9.79E-6 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS01720 52601646795dfe1a244adbdd0b9834ab 997 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 438 820 2.2E-37 T 22-04-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 HRM2_RS07865 21c78dd16d598f2a6072063af55f3ac1 294 SUPERFAMILY SSF46689 111 163 4.61E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS07865 21c78dd16d598f2a6072063af55f3ac1 294 Pfam PF00440 Bacterial regulatory proteins, tetR family 128 157 8.0E-10 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS07865 21c78dd16d598f2a6072063af55f3ac1 294 PANTHER PTHR30055 97 287 1.2E-14 T 22-04-2016 HRM2_RS07865 21c78dd16d598f2a6072063af55f3ac1 294 SUPERFAMILY SSF48498 179 289 1.96E-6 T 22-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal HRM2_RS07865 21c78dd16d598f2a6072063af55f3ac1 294 Gene3D G3DSA:1.10.357.10 128 289 2.6E-23 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HRM2_RS13860 32c1e9ac563300ba49d8f1b11ef2b729 696 Gene3D G3DSA:1.10.10.480 425 455 2.7E-6 T 22-04-2016 IPR013981 Pyrophosphate-dependent phosphofructokinase, alpha-helical domain UniPathway: UPA00109 HRM2_RS13860 32c1e9ac563300ba49d8f1b11ef2b729 696 PANTHER PTHR13697:SF2 1 303 1.0E-133 T 22-04-2016 HRM2_RS13860 32c1e9ac563300ba49d8f1b11ef2b729 696 PANTHER PTHR13697:SF2 323 372 1.0E-133 T 22-04-2016 HRM2_RS13860 32c1e9ac563300ba49d8f1b11ef2b729 696 PANTHER PTHR13697:SF2 540 693 1.0E-133 T 22-04-2016 HRM2_RS13860 32c1e9ac563300ba49d8f1b11ef2b729 696 PANTHER PTHR13697 1 303 1.0E-133 T 22-04-2016 HRM2_RS13860 32c1e9ac563300ba49d8f1b11ef2b729 696 PANTHER PTHR13697 323 372 1.0E-133 T 22-04-2016 HRM2_RS13860 32c1e9ac563300ba49d8f1b11ef2b729 696 PANTHER PTHR13697 540 693 1.0E-133 T 22-04-2016 HRM2_RS13860 32c1e9ac563300ba49d8f1b11ef2b729 696 SUPERFAMILY SSF53784 540 691 4.32E-24 T 22-04-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS13860 32c1e9ac563300ba49d8f1b11ef2b729 696 Pfam PF00365 Phosphofructokinase 98 308 6.6E-32 T 22-04-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS13860 32c1e9ac563300ba49d8f1b11ef2b729 696 SUPERFAMILY SSF53784 90 486 3.66E-90 T 22-04-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS13860 32c1e9ac563300ba49d8f1b11ef2b729 696 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 101 120 4.6E-10 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS13860 32c1e9ac563300ba49d8f1b11ef2b729 696 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 350 362 4.6E-10 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS13860 32c1e9ac563300ba49d8f1b11ef2b729 696 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 397 419 4.6E-10 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS13860 32c1e9ac563300ba49d8f1b11ef2b729 696 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 190 206 4.6E-10 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS13860 32c1e9ac563300ba49d8f1b11ef2b729 696 Gene3D G3DSA:3.40.50.450 31 307 1.6E-72 T 22-04-2016 HRM2_RS17355 7f75b3a0676f26c43f9b5dc3a7828e03 265 Gene3D G3DSA:3.90.550.10 22 262 1.5E-66 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS17355 7f75b3a0676f26c43f9b5dc3a7828e03 265 SUPERFAMILY SSF53448 22 261 3.34E-57 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS17355 7f75b3a0676f26c43f9b5dc3a7828e03 265 PANTHER PTHR22572 22 262 8.9E-85 T 22-04-2016 HRM2_RS17355 7f75b3a0676f26c43f9b5dc3a7828e03 265 PANTHER PTHR22572:SF115 22 262 8.9E-85 T 22-04-2016 HRM2_RS17355 7f75b3a0676f26c43f9b5dc3a7828e03 265 Pfam PF12804 MobA-like NTP transferase domain 23 165 1.2E-22 T 22-04-2016 IPR025877 MobA-like NTP transferase HRM2_RS11355 cb601b615b9f5fc3a319120e85c221d0 668 Gene3D G3DSA:1.10.3150.10 20 290 3.3E-66 T 22-04-2016 IPR013976 Metal-dependent hydrolase HDOD HRM2_RS11355 cb601b615b9f5fc3a319120e85c221d0 668 TIGRFAM TIGR00277 HDIG: HDIG domain 122 220 2.6E-7 T 22-04-2016 IPR006675 HDIG domain HRM2_RS11355 cb601b615b9f5fc3a319120e85c221d0 668 SMART SM00267 494 668 7.0E-48 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS11355 cb601b615b9f5fc3a319120e85c221d0 668 PANTHER PTHR33525:SF3 24 301 4.9E-49 T 22-04-2016 HRM2_RS11355 cb601b615b9f5fc3a319120e85c221d0 668 SUPERFAMILY SSF55073 510 667 7.53E-44 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS11355 cb601b615b9f5fc3a319120e85c221d0 668 Gene3D G3DSA:3.30.450.40 350 505 3.6E-12 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS11355 cb601b615b9f5fc3a319120e85c221d0 668 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 503 667 3.5E-48 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS11355 cb601b615b9f5fc3a319120e85c221d0 668 PANTHER PTHR33525 24 301 4.9E-49 T 22-04-2016 HRM2_RS11355 cb601b615b9f5fc3a319120e85c221d0 668 Pfam PF08668 HDOD domain 25 220 3.6E-48 T 22-04-2016 IPR013976 Metal-dependent hydrolase HDOD HRM2_RS11355 cb601b615b9f5fc3a319120e85c221d0 668 Gene3D G3DSA:3.30.70.270 507 667 1.4E-45 T 22-04-2016 HRM2_RS11355 cb601b615b9f5fc3a319120e85c221d0 668 SUPERFAMILY SSF55781 346 504 1.07E-11 T 22-04-2016 IPR029016 GAF domain-like HRM2_RS11355 cb601b615b9f5fc3a319120e85c221d0 668 SUPERFAMILY SSF109604 19 281 2.3E-57 T 22-04-2016 HRM2_RS11355 cb601b615b9f5fc3a319120e85c221d0 668 Pfam PF00990 Diguanylate cyclase, GGDEF domain 507 664 7.2E-42 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS11215 801bd75d0e5f555fc4964bbfb5898d98 541 SUPERFAMILY SSF161098 281 534 2.75E-45 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS11215 801bd75d0e5f555fc4964bbfb5898d98 541 Gene3D G3DSA:1.10.3720.10 5 252 7.3E-43 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS11215 801bd75d0e5f555fc4964bbfb5898d98 541 PANTHER PTHR30183:SF8 56 540 1.1E-98 T 22-04-2016 HRM2_RS11215 801bd75d0e5f555fc4964bbfb5898d98 541 PANTHER PTHR30183 56 540 1.1E-98 T 22-04-2016 HRM2_RS11215 801bd75d0e5f555fc4964bbfb5898d98 541 SUPERFAMILY SSF161098 4 258 2.18E-49 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS11215 801bd75d0e5f555fc4964bbfb5898d98 541 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 352 525 1.2E-9 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS11215 801bd75d0e5f555fc4964bbfb5898d98 541 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 259 5.0E-20 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS11215 801bd75d0e5f555fc4964bbfb5898d98 541 Gene3D G3DSA:1.10.3720.10 282 534 2.5E-42 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS01475 ee2722f5852c1d502e8e1202a129f1ad 240 SMART SM00855 3 183 1.2E-6 T 22-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 HRM2_RS01475 ee2722f5852c1d502e8e1202a129f1ad 240 SUPERFAMILY SSF53254 1 231 4.71E-32 T 22-04-2016 IPR029033 Histidine phosphatase superfamily HRM2_RS01475 ee2722f5852c1d502e8e1202a129f1ad 240 PANTHER PTHR20935:SF1 167 239 9.0E-16 T 22-04-2016 HRM2_RS01475 ee2722f5852c1d502e8e1202a129f1ad 240 PANTHER PTHR20935:SF1 1 125 9.0E-16 T 22-04-2016 HRM2_RS01475 ee2722f5852c1d502e8e1202a129f1ad 240 Gene3D G3DSA:3.40.50.1240 3 229 1.6E-27 T 22-04-2016 IPR029033 Histidine phosphatase superfamily HRM2_RS01475 ee2722f5852c1d502e8e1202a129f1ad 240 PANTHER PTHR20935 167 239 9.0E-16 T 22-04-2016 HRM2_RS01475 ee2722f5852c1d502e8e1202a129f1ad 240 PANTHER PTHR20935 1 125 9.0E-16 T 22-04-2016 HRM2_RS01475 ee2722f5852c1d502e8e1202a129f1ad 240 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 93 223 5.5E-12 T 22-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 HRM2_RS01475 ee2722f5852c1d502e8e1202a129f1ad 240 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 61 2.7E-7 T 22-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 HRM2_RS03120 06f84be7a92b8d77c2f16f8ee57afcac 276 Gene3D G3DSA:3.40.50.1820 7 274 1.6E-49 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS03120 06f84be7a92b8d77c2f16f8ee57afcac 276 PANTHER PTHR11614 27 275 6.2E-70 T 22-04-2016 HRM2_RS03120 06f84be7a92b8d77c2f16f8ee57afcac 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 214 228 6.4E-9 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HRM2_RS03120 06f84be7a92b8d77c2f16f8ee57afcac 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 6.4E-9 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HRM2_RS03120 06f84be7a92b8d77c2f16f8ee57afcac 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 120 133 6.4E-9 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HRM2_RS03120 06f84be7a92b8d77c2f16f8ee57afcac 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 57 72 6.4E-9 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HRM2_RS03120 06f84be7a92b8d77c2f16f8ee57afcac 276 SUPERFAMILY SSF53474 20 274 1.47E-41 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS03120 06f84be7a92b8d77c2f16f8ee57afcac 276 Pfam PF12146 Serine aminopeptidase, S33 28 258 1.0E-70 T 22-04-2016 IPR022742 Serine aminopeptidase, S33 HRM2_RS04985 9bdd2630a1535a384146d0d05179d922 345 Pfam PF16884 N-terminal domain of oxidoreductase 9 115 3.5E-40 T 22-04-2016 HRM2_RS04985 9bdd2630a1535a384146d0d05179d922 345 Gene3D G3DSA:3.40.50.720 143 309 3.6E-64 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS04985 9bdd2630a1535a384146d0d05179d922 345 PANTHER PTHR11695:SF557 26 345 1.0E-169 T 22-04-2016 HRM2_RS04985 9bdd2630a1535a384146d0d05179d922 345 SMART SM00829 21 339 1.1E-4 T 22-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 HRM2_RS04985 9bdd2630a1535a384146d0d05179d922 345 Gene3D G3DSA:3.90.180.10 3 142 2.2E-53 T 22-04-2016 IPR011032 GroES-like HRM2_RS04985 9bdd2630a1535a384146d0d05179d922 345 PANTHER PTHR11695 26 345 1.0E-169 T 22-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 HRM2_RS04985 9bdd2630a1535a384146d0d05179d922 345 SUPERFAMILY SSF51735 127 306 3.26E-44 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS04985 9bdd2630a1535a384146d0d05179d922 345 SUPERFAMILY SSF50129 7 147 3.21E-42 T 22-04-2016 IPR011032 GroES-like HRM2_RS04985 9bdd2630a1535a384146d0d05179d922 345 Pfam PF00107 Zinc-binding dehydrogenase 161 296 7.5E-20 T 22-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 HRM2_RS16350 e129d8261551f199a1101c5b32792b96 277 SUPERFAMILY SSF53850 6 267 1.67E-68 T 22-04-2016 HRM2_RS16350 e129d8261551f199a1101c5b32792b96 277 Pfam PF02621 Menaquinone biosynthesis 6 261 1.3E-57 T 22-04-2016 IPR003773 Menaquinone biosynthesis enzyme UniPathway: UPA00079 HRM2_RS16350 e129d8261551f199a1101c5b32792b96 277 PANTHER PTHR37690 1 277 1.0E-52 T 22-04-2016 HRM2_RS16350 e129d8261551f199a1101c5b32792b96 277 Hamap MF_00995 Chorismate dehydratase [mqnA]. 7 266 27.562 T 22-04-2016 IPR030868 Chorismate dehydratase GO:0009234|GO:0016829 KEGG: 00130+4.2.1.151|MetaCyc: PWY-7371|MetaCyc: PWY-7374|UniPathway: UPA00079 HRM2_RS16350 e129d8261551f199a1101c5b32792b96 277 Gene3D G3DSA:3.40.190.10 179 276 3.4E-51 T 22-04-2016 HRM2_RS16350 e129d8261551f199a1101c5b32792b96 277 Gene3D G3DSA:3.40.190.10 3 79 3.4E-51 T 22-04-2016 HRM2_RS16350 e129d8261551f199a1101c5b32792b96 277 Gene3D G3DSA:3.40.190.10 80 178 5.9E-25 T 22-04-2016 HRM2_RS05520 fb176615d990980b317617dfd589cb1c 195 Pfam PF14334 Domain of unknown function (DUF4390) 34 191 2.1E-41 T 22-04-2016 IPR025500 Protein of unknown function DUF4390 HRM2_RS18940 9b19f25baabe1fa62464524c94e5a3c5 282 PANTHER PTHR30579 1 274 2.1E-76 T 22-04-2016 HRM2_RS18940 9b19f25baabe1fa62464524c94e5a3c5 282 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 3.1E-19 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HRM2_RS18940 9b19f25baabe1fa62464524c94e5a3c5 282 SUPERFAMILY SSF53850 88 280 9.1E-29 T 22-04-2016 HRM2_RS18940 9b19f25baabe1fa62464524c94e5a3c5 282 Gene3D G3DSA:3.40.190.10 186 242 1.8E-6 T 22-04-2016 HRM2_RS18940 9b19f25baabe1fa62464524c94e5a3c5 282 Gene3D G3DSA:3.40.190.10 88 185 2.2E-18 T 22-04-2016 HRM2_RS18940 9b19f25baabe1fa62464524c94e5a3c5 282 SUPERFAMILY SSF46785 3 111 7.52E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS18940 9b19f25baabe1fa62464524c94e5a3c5 282 PANTHER PTHR30579:SF6 1 274 2.1E-76 T 22-04-2016 HRM2_RS18940 9b19f25baabe1fa62464524c94e5a3c5 282 Gene3D G3DSA:1.10.10.10 2 83 8.8E-25 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS18940 9b19f25baabe1fa62464524c94e5a3c5 282 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 9.7E-8 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HRM2_RS18940 9b19f25baabe1fa62464524c94e5a3c5 282 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 9.7E-8 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HRM2_RS18940 9b19f25baabe1fa62464524c94e5a3c5 282 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 9.7E-8 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HRM2_RS18940 9b19f25baabe1fa62464524c94e5a3c5 282 Pfam PF03466 LysR substrate binding domain 90 275 1.2E-26 T 22-04-2016 IPR005119 LysR, substrate-binding HRM2_RS00730 6d5f6d4030f8b7dd1088eeace4bc11b3 247 Pfam PF00005 ABC transporter 27 164 7.6E-27 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS00730 6d5f6d4030f8b7dd1088eeace4bc11b3 247 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS00730 6d5f6d4030f8b7dd1088eeace4bc11b3 247 SMART SM00382 36 214 8.4E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS00730 6d5f6d4030f8b7dd1088eeace4bc11b3 247 Gene3D G3DSA:3.40.50.300 6 235 1.1E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00730 6d5f6d4030f8b7dd1088eeace4bc11b3 247 PANTHER PTHR24220 9 224 8.7E-79 T 22-04-2016 HRM2_RS00730 6d5f6d4030f8b7dd1088eeace4bc11b3 247 SUPERFAMILY SSF52540 8 223 6.23E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22425 52f972f3b33150d2549f7f8d6802e283 336 PANTHER PTHR30465:SF0 191 334 2.3E-141 T 22-04-2016 HRM2_RS22425 52f972f3b33150d2549f7f8d6802e283 336 PANTHER PTHR30465:SF0 1 169 2.3E-141 T 22-04-2016 HRM2_RS22425 52f972f3b33150d2549f7f8d6802e283 336 SUPERFAMILY SSF161098 197 317 1.57E-20 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS22425 52f972f3b33150d2549f7f8d6802e283 336 SUPERFAMILY SSF161098 92 160 1.57E-20 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS22425 52f972f3b33150d2549f7f8d6802e283 336 Gene3D G3DSA:1.10.3720.10 89 163 4.7E-22 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS22425 52f972f3b33150d2549f7f8d6802e283 336 Gene3D G3DSA:1.10.3720.10 200 328 4.7E-22 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS22425 52f972f3b33150d2549f7f8d6802e283 336 PANTHER PTHR30465 191 334 2.3E-141 T 22-04-2016 HRM2_RS22425 52f972f3b33150d2549f7f8d6802e283 336 PANTHER PTHR30465 1 169 2.3E-141 T 22-04-2016 HRM2_RS22425 52f972f3b33150d2549f7f8d6802e283 336 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 333 2.1E-46 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS15680 1f08ff08666acddda1bab2c3e81769d9 129 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 8 113 20.594 T 22-04-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS HRM2_RS15680 1f08ff08666acddda1bab2c3e81769d9 129 Pfam PF02410 Ribosomal silencing factor during starvation 25 112 5.9E-22 T 22-04-2016 HRM2_RS15680 1f08ff08666acddda1bab2c3e81769d9 129 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 25 112 2.8E-30 T 22-04-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS HRM2_RS15680 1f08ff08666acddda1bab2c3e81769d9 129 SUPERFAMILY SSF81301 25 123 1.1E-32 T 22-04-2016 HRM2_RS15680 1f08ff08666acddda1bab2c3e81769d9 129 Gene3D G3DSA:3.30.460.10 25 116 6.4E-31 T 22-04-2016 HRM2_RS15680 1f08ff08666acddda1bab2c3e81769d9 129 PANTHER PTHR21043 25 122 5.5E-33 T 22-04-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS HRM2_RS10980 e90d6c92863abfb35ef127e33833beae 441 SUPERFAMILY SSF53383 31 416 3.78E-49 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS10980 e90d6c92863abfb35ef127e33833beae 441 Pfam PF00155 Aminotransferase class I and II 79 414 3.4E-26 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HRM2_RS10980 e90d6c92863abfb35ef127e33833beae 441 PANTHER PTHR11751 308 429 2.7E-34 T 22-04-2016 HRM2_RS10980 e90d6c92863abfb35ef127e33833beae 441 PANTHER PTHR11751 82 290 2.7E-34 T 22-04-2016 HRM2_RS10980 e90d6c92863abfb35ef127e33833beae 441 Gene3D G3DSA:3.40.640.10 79 336 3.2E-41 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS10980 e90d6c92863abfb35ef127e33833beae 441 PANTHER PTHR11751:SF370 308 429 2.7E-34 T 22-04-2016 HRM2_RS10980 e90d6c92863abfb35ef127e33833beae 441 PANTHER PTHR11751:SF370 82 290 2.7E-34 T 22-04-2016 HRM2_RS18515 77e7b05dd3a15454f468732eceef8167 213 Gene3D G3DSA:3.30.1330.60 102 210 5.1E-39 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS18515 77e7b05dd3a15454f468732eceef8167 213 Pfam PF13488 Glycine zipper 36 81 8.8E-11 T 22-04-2016 HRM2_RS18515 77e7b05dd3a15454f468732eceef8167 213 PRINTS PR01021 OMPA domain signature 113 135 3.5E-19 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 HRM2_RS18515 77e7b05dd3a15454f468732eceef8167 213 PRINTS PR01021 OMPA domain signature 158 174 3.5E-19 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 HRM2_RS18515 77e7b05dd3a15454f468732eceef8167 213 PRINTS PR01021 OMPA domain signature 143 158 3.5E-19 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 HRM2_RS18515 77e7b05dd3a15454f468732eceef8167 213 SUPERFAMILY SSF103088 104 211 2.09E-37 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS18515 77e7b05dd3a15454f468732eceef8167 213 Pfam PF00691 OmpA family 112 203 1.0E-27 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS18515 77e7b05dd3a15454f468732eceef8167 213 PANTHER PTHR30128 35 213 1.0E-47 T 22-04-2016 HRM2_RS18515 77e7b05dd3a15454f468732eceef8167 213 ProSitePatterns PS01068 OmpA-like domain. 145 189 - T 22-04-2016 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 HRM2_RS20900 aa411f8c08d5b087e31eb9dc26af188c 220 PANTHER PTHR23083 11 203 5.0E-24 T 22-04-2016 HRM2_RS20900 aa411f8c08d5b087e31eb9dc26af188c 220 Pfam PF13432 Tetratricopeptide repeat 32 85 3.7E-5 T 22-04-2016 HRM2_RS20900 aa411f8c08d5b087e31eb9dc26af188c 220 Pfam PF00515 Tetratricopeptide repeat 175 203 1.3E-6 T 22-04-2016 IPR001440 Tetratricopeptide repeat 1 GO:0005515 HRM2_RS20900 aa411f8c08d5b087e31eb9dc26af188c 220 Gene3D G3DSA:1.25.40.10 11 213 5.5E-31 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS20900 aa411f8c08d5b087e31eb9dc26af188c 220 SMART SM00028 62 95 190.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS20900 aa411f8c08d5b087e31eb9dc26af188c 220 SMART SM00028 28 61 0.065 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS20900 aa411f8c08d5b087e31eb9dc26af188c 220 SMART SM00028 174 207 0.02 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS20900 aa411f8c08d5b087e31eb9dc26af188c 220 SMART SM00028 96 139 79.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS20900 aa411f8c08d5b087e31eb9dc26af188c 220 SMART SM00028 140 173 28.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS20900 aa411f8c08d5b087e31eb9dc26af188c 220 SUPERFAMILY SSF48452 10 209 2.28E-21 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS00810 d6bdff786a092cbe8a00384faa0dcdfd 265 Gene3D G3DSA:1.10.3720.10 13 263 3.3E-40 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS00810 d6bdff786a092cbe8a00384faa0dcdfd 265 TIGRFAM TIGR01581 Mo_ABC_porter: NifC-like ABC-type porter 37 256 1.0E-71 T 22-04-2016 IPR006469 NifC-like ABC-type porter GO:0005215|GO:0006810|GO:0016020 HRM2_RS00810 d6bdff786a092cbe8a00384faa0dcdfd 265 PANTHER PTHR30406 7 262 3.5E-68 T 22-04-2016 HRM2_RS00810 d6bdff786a092cbe8a00384faa0dcdfd 265 SUPERFAMILY SSF161098 14 260 2.52E-44 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS00810 d6bdff786a092cbe8a00384faa0dcdfd 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 256 5.7E-16 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS00810 d6bdff786a092cbe8a00384faa0dcdfd 265 PANTHER PTHR30406:SF1 7 262 3.5E-68 T 22-04-2016 HRM2_RS14480 0396aef9354238797c2b4a68c99c5176 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 22-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 HRM2_RS14480 0396aef9354238797c2b4a68c99c5176 252 PANTHER PTHR24322:SF409 13 142 1.1E-54 T 22-04-2016 HRM2_RS14480 0396aef9354238797c2b4a68c99c5176 252 PANTHER PTHR24322:SF409 158 190 1.1E-54 T 22-04-2016 HRM2_RS14480 0396aef9354238797c2b4a68c99c5176 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 250 2.9E-66 T 22-04-2016 HRM2_RS14480 0396aef9354238797c2b4a68c99c5176 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 8.0E-41 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS14480 0396aef9354238797c2b4a68c99c5176 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 8.0E-41 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS14480 0396aef9354238797c2b4a68c99c5176 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 8.0E-41 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS14480 0396aef9354238797c2b4a68c99c5176 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 8.0E-41 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS14480 0396aef9354238797c2b4a68c99c5176 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 8.0E-41 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS14480 0396aef9354238797c2b4a68c99c5176 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 8.0E-41 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS14480 0396aef9354238797c2b4a68c99c5176 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 4.0E-12 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS14480 0396aef9354238797c2b4a68c99c5176 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 4.0E-12 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS14480 0396aef9354238797c2b4a68c99c5176 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 4.0E-12 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS14480 0396aef9354238797c2b4a68c99c5176 252 SUPERFAMILY SSF51735 7 251 5.57E-87 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS14480 0396aef9354238797c2b4a68c99c5176 252 PANTHER PTHR24322 13 142 1.1E-54 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS14480 0396aef9354238797c2b4a68c99c5176 252 PANTHER PTHR24322 158 190 1.1E-54 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS14480 0396aef9354238797c2b4a68c99c5176 252 Gene3D G3DSA:3.40.50.720 4 251 2.1E-86 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS10900 f2bf6b689da3ab4d3645d1d366628071 240 PANTHER PTHR30035:SF3 34 234 2.0E-42 T 22-04-2016 HRM2_RS10900 f2bf6b689da3ab4d3645d1d366628071 240 PANTHER PTHR30035 34 234 2.0E-42 T 22-04-2016 IPR007428 MlaA lipoprotein GO:0016020 HRM2_RS10900 f2bf6b689da3ab4d3645d1d366628071 240 PRINTS PR01805 VacJ lipoprotein signature 61 77 4.5E-15 T 22-04-2016 IPR007428 MlaA lipoprotein GO:0016020 HRM2_RS10900 f2bf6b689da3ab4d3645d1d366628071 240 PRINTS PR01805 VacJ lipoprotein signature 112 129 4.5E-15 T 22-04-2016 IPR007428 MlaA lipoprotein GO:0016020 HRM2_RS10900 f2bf6b689da3ab4d3645d1d366628071 240 PRINTS PR01805 VacJ lipoprotein signature 149 166 4.5E-15 T 22-04-2016 IPR007428 MlaA lipoprotein GO:0016020 HRM2_RS10900 f2bf6b689da3ab4d3645d1d366628071 240 PRINTS PR01805 VacJ lipoprotein signature 44 57 4.5E-15 T 22-04-2016 IPR007428 MlaA lipoprotein GO:0016020 HRM2_RS10900 f2bf6b689da3ab4d3645d1d366628071 240 Pfam PF04333 MlaA lipoprotein 43 236 4.4E-65 T 22-04-2016 IPR007428 MlaA lipoprotein GO:0016020 HRM2_RS21400 e662b0b30127ac886fb98fcda2767bf4 150 Gene3D G3DSA:3.30.310.70 23 147 4.5E-30 T 22-04-2016 IPR005180 Domain of unknown function DUF302 HRM2_RS21400 e662b0b30127ac886fb98fcda2767bf4 150 Pfam PF03625 Domain of unknown function DUF302 55 117 1.4E-17 T 22-04-2016 IPR005180 Domain of unknown function DUF302 HRM2_RS21400 e662b0b30127ac886fb98fcda2767bf4 150 SUPERFAMILY SSF103247 24 147 5.62E-32 T 22-04-2016 IPR005180 Domain of unknown function DUF302 HRM2_RS17270 36ecdf5804d76aae38b07513d1ee4886 345 SUPERFAMILY SSF54506 12 343 2.24E-88 T 22-04-2016 HRM2_RS17270 36ecdf5804d76aae38b07513d1ee4886 345 PIRSF PIRSF029792 12 345 7.1E-102 T 22-04-2016 IPR008794 Proline racemase family HRM2_RS17270 36ecdf5804d76aae38b07513d1ee4886 345 Pfam PF05544 Proline racemase 21 343 6.5E-98 T 22-04-2016 IPR008794 Proline racemase family HRM2_RS17270 36ecdf5804d76aae38b07513d1ee4886 345 Gene3D G3DSA:3.10.310.10 13 166 1.4E-47 T 22-04-2016 HRM2_RS17270 36ecdf5804d76aae38b07513d1ee4886 345 PANTHER PTHR33442 5 345 1.1E-105 T 22-04-2016 HRM2_RS17270 36ecdf5804d76aae38b07513d1ee4886 345 PANTHER PTHR33442:SF2 5 345 1.1E-105 T 22-04-2016 HRM2_RS17270 36ecdf5804d76aae38b07513d1ee4886 345 Gene3D G3DSA:3.10.310.10 167 333 7.6E-55 T 22-04-2016 HRM2_RS01535 de557447f06dee827403cb8036c9875a 126 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 5 124 4.2E-52 T 22-04-2016 IPR006056 RidA family HRM2_RS01535 de557447f06dee827403cb8036c9875a 126 SUPERFAMILY SSF55298 1 126 1.54E-44 T 22-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like HRM2_RS01535 de557447f06dee827403cb8036c9875a 126 PANTHER PTHR11803 1 126 7.5E-55 T 22-04-2016 IPR006175 YjgF/YER057c/UK114 family HRM2_RS01535 de557447f06dee827403cb8036c9875a 126 Pfam PF01042 Endoribonuclease L-PSP 9 125 2.2E-41 T 22-04-2016 IPR006175 YjgF/YER057c/UK114 family HRM2_RS01535 de557447f06dee827403cb8036c9875a 126 Gene3D G3DSA:3.30.1330.40 3 123 4.1E-47 T 22-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like HRM2_RS00210 3f1736af56373768db2836dc8087cde3 506 PANTHER PTHR30097 66 477 2.5E-87 T 22-04-2016 HRM2_RS00210 3f1736af56373768db2836dc8087cde3 506 Gene3D G3DSA:2.40.50.100 278 310 1.9E-9 T 22-04-2016 HRM2_RS00210 3f1736af56373768db2836dc8087cde3 506 Gene3D G3DSA:2.40.50.100 189 220 1.9E-9 T 22-04-2016 HRM2_RS00210 3f1736af56373768db2836dc8087cde3 506 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 169 384 5.7E-73 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain HRM2_RS00210 3f1736af56373768db2836dc8087cde3 506 SUPERFAMILY SSF111369 188 391 8.37E-17 T 22-04-2016 HRM2_RS00210 3f1736af56373768db2836dc8087cde3 506 PANTHER PTHR30097:SF3 66 477 2.5E-87 T 22-04-2016 HRM2_RS00210 3f1736af56373768db2836dc8087cde3 506 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 160 465 1.6E-33 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 HRM2_RS17245 9263b855bcde2638dcb5b8dfdba34ebd 370 SUPERFAMILY SSF52540 11 249 2.87E-85 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17245 9263b855bcde2638dcb5b8dfdba34ebd 370 SUPERFAMILY SSF50331 244 364 2.93E-13 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal HRM2_RS17245 9263b855bcde2638dcb5b8dfdba34ebd 370 PANTHER PTHR24220 12 262 9.7E-128 T 22-04-2016 HRM2_RS17245 9263b855bcde2638dcb5b8dfdba34ebd 370 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS17245 9263b855bcde2638dcb5b8dfdba34ebd 370 PANTHER PTHR24220:SF150 12 262 9.7E-128 T 22-04-2016 HRM2_RS17245 9263b855bcde2638dcb5b8dfdba34ebd 370 SMART SM00382 35 218 2.5E-19 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS17245 9263b855bcde2638dcb5b8dfdba34ebd 370 Pfam PF08402 TOBE domain 287 364 3.2E-10 T 22-04-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 HRM2_RS17245 9263b855bcde2638dcb5b8dfdba34ebd 370 Pfam PF00005 ABC transporter 27 168 4.7E-36 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS17245 9263b855bcde2638dcb5b8dfdba34ebd 370 Gene3D G3DSA:3.40.50.300 10 241 6.4E-78 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20125 1806ff844f28b219f049caf493899e21 323 PANTHER PTHR13734:SF42 15 281 2.1E-14 T 22-04-2016 HRM2_RS20125 1806ff844f28b219f049caf493899e21 323 Gene3D G3DSA:3.90.1640.10 24 183 2.3E-25 T 22-04-2016 HRM2_RS20125 1806ff844f28b219f049caf493899e21 323 SUPERFAMILY SSF64182 24 300 9.16E-44 T 22-04-2016 HRM2_RS20125 1806ff844f28b219f049caf493899e21 323 Pfam PF01368 DHH family 20 157 3.2E-8 T 22-04-2016 IPR001667 DDH domain HRM2_RS20125 1806ff844f28b219f049caf493899e21 323 PANTHER PTHR13734 15 281 2.1E-14 T 22-04-2016 HRM2_RS20715 77b20513f2bada8b239b8e3c3a31124d 292 Gene3D G3DSA:1.20.1510.10 9 200 2.3E-45 T 22-04-2016 IPR027469 Cation efflux protein transmembrane domain HRM2_RS20715 77b20513f2bada8b239b8e3c3a31124d 292 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 9 289 8.0E-70 T 22-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 HRM2_RS20715 77b20513f2bada8b239b8e3c3a31124d 292 Pfam PF01545 Cation efflux family 13 207 2.8E-47 T 22-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 HRM2_RS20715 77b20513f2bada8b239b8e3c3a31124d 292 SUPERFAMILY SSF160240 211 290 1.44E-22 T 22-04-2016 HRM2_RS20715 77b20513f2bada8b239b8e3c3a31124d 292 PANTHER PTHR11562 10 288 7.7E-86 T 22-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 HRM2_RS20715 77b20513f2bada8b239b8e3c3a31124d 292 Gene3D G3DSA:3.30.70.1350 209 288 6.0E-26 T 22-04-2016 IPR027470 Cation efflux protein, cytoplasmic domain HRM2_RS20715 77b20513f2bada8b239b8e3c3a31124d 292 SUPERFAMILY SSF161111 8 208 4.97E-50 T 22-04-2016 HRM2_RS20715 77b20513f2bada8b239b8e3c3a31124d 292 PANTHER PTHR11562:SF18 10 288 7.7E-86 T 22-04-2016 HRM2_RS20715 77b20513f2bada8b239b8e3c3a31124d 292 Pfam PF16916 Dimerisation domain of Zinc Transporter 212 288 4.5E-25 T 22-04-2016 IPR027470 Cation efflux protein, cytoplasmic domain HRM2_RS14440 4ac7bdb6e3b64958f942f8c9dcf9f4f0 775 SMART SM00763 37 470 1.9E-4 T 22-04-2016 IPR013153 PrkA AAA domain HRM2_RS14440 4ac7bdb6e3b64958f942f8c9dcf9f4f0 775 PANTHER PTHR30267 492 775 4.2E-130 T 22-04-2016 HRM2_RS14440 4ac7bdb6e3b64958f942f8c9dcf9f4f0 775 PANTHER PTHR30267 204 475 4.2E-130 T 22-04-2016 HRM2_RS14440 4ac7bdb6e3b64958f942f8c9dcf9f4f0 775 PANTHER PTHR30267 17 172 4.2E-130 T 22-04-2016 HRM2_RS14440 4ac7bdb6e3b64958f942f8c9dcf9f4f0 775 Gene3D G3DSA:3.40.50.300 318 419 9.1E-4 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14440 4ac7bdb6e3b64958f942f8c9dcf9f4f0 775 Gene3D G3DSA:3.40.50.300 124 139 9.1E-4 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14440 4ac7bdb6e3b64958f942f8c9dcf9f4f0 775 Gene3D G3DSA:3.40.50.300 140 190 2.7E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14440 4ac7bdb6e3b64958f942f8c9dcf9f4f0 775 Pfam PF06798 PrkA serine protein kinase C-terminal domain 492 764 5.9E-57 T 22-04-2016 IPR010650 PrkA C-terminal domain HRM2_RS14440 4ac7bdb6e3b64958f942f8c9dcf9f4f0 775 Pfam PF08298 PrkA AAA domain 262 468 6.6E-7 T 22-04-2016 IPR013153 PrkA AAA domain HRM2_RS14440 4ac7bdb6e3b64958f942f8c9dcf9f4f0 775 SUPERFAMILY SSF52540 119 177 1.62E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14440 4ac7bdb6e3b64958f942f8c9dcf9f4f0 775 SUPERFAMILY SSF52540 344 497 1.62E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14440 4ac7bdb6e3b64958f942f8c9dcf9f4f0 775 PANTHER PTHR30267:SF2 492 775 4.2E-130 T 22-04-2016 HRM2_RS14440 4ac7bdb6e3b64958f942f8c9dcf9f4f0 775 PANTHER PTHR30267:SF2 204 475 4.2E-130 T 22-04-2016 HRM2_RS14440 4ac7bdb6e3b64958f942f8c9dcf9f4f0 775 PANTHER PTHR30267:SF2 17 172 4.2E-130 T 22-04-2016 HRM2_RS19465 8d571571311c82a785cda11df23da66a 432 SUPERFAMILY SSF53098 161 380 1.44E-5 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS19465 8d571571311c82a785cda11df23da66a 432 Pfam PF13701 Transposase DDE domain group 1 4 429 5.1E-53 T 22-04-2016 IPR025668 Transposase DDE domain HRM2_RS14855 30672868260d905348f6902159639d54 686 PANTHER PTHR32552:SF25 50 193 3.8E-18 T 22-04-2016 HRM2_RS14855 30672868260d905348f6902159639d54 686 PANTHER PTHR32552 50 193 3.8E-18 T 22-04-2016 HRM2_RS14855 30672868260d905348f6902159639d54 686 Gene3D G3DSA:2.170.130.10 52 166 3.6E-21 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 HRM2_RS14855 30672868260d905348f6902159639d54 686 Pfam PF00593 TonB dependent receptor 437 666 1.4E-10 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 HRM2_RS14855 30672868260d905348f6902159639d54 686 Gene3D G3DSA:2.40.170.20 167 684 2.8E-32 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 HRM2_RS14855 30672868260d905348f6902159639d54 686 Pfam PF07715 TonB-dependent Receptor Plug Domain 64 166 2.0E-11 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 HRM2_RS14855 30672868260d905348f6902159639d54 686 SUPERFAMILY SSF56935 54 685 2.25E-57 T 22-04-2016 HRM2_RS16995 70ee887f1ee14723bae89789cca7f588 131 PANTHER PTHR37164 3 125 3.0E-18 T 22-04-2016 HRM2_RS16995 70ee887f1ee14723bae89789cca7f588 131 Pfam PF01814 Hemerythrin HHE cation binding domain 17 119 4.8E-11 T 22-04-2016 IPR012312 Haemerythrin-like HRM2_RS16995 70ee887f1ee14723bae89789cca7f588 131 Gene3D G3DSA:1.20.120.50 4 119 6.3E-32 T 22-04-2016 IPR012827 Haemerythrin, metal-binding domain GO:0046872 HRM2_RS16995 70ee887f1ee14723bae89789cca7f588 131 SUPERFAMILY SSF47188 3 119 7.46E-29 T 22-04-2016 IPR012827 Haemerythrin, metal-binding domain GO:0046872 HRM2_RS16995 70ee887f1ee14723bae89789cca7f588 131 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 7 119 1.7E-30 T 22-04-2016 IPR012827 Haemerythrin, metal-binding domain GO:0046872 HRM2_RS16995 70ee887f1ee14723bae89789cca7f588 131 ProSitePatterns PS00550 Hemerythrin family signature. 54 77 - T 22-04-2016 IPR016131 Haemerythrin, iron-binding site GO:0046872 HRM2_RS19100 831b31aecc96f4147e1469f650cb4c32 1048 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 664 884 5.0E-21 T 22-04-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 HRM2_RS19100 831b31aecc96f4147e1469f650cb4c32 1048 SUPERFAMILY SSF51735 805 914 9.85E-13 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS19100 831b31aecc96f4147e1469f650cb4c32 1048 SUPERFAMILY SSF51735 671 767 9.85E-13 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS19100 831b31aecc96f4147e1469f650cb4c32 1048 PANTHER PTHR11606 666 1028 9.2E-83 T 22-04-2016 HRM2_RS19100 831b31aecc96f4147e1469f650cb4c32 1048 PANTHER PTHR11606 435 619 9.2E-83 T 22-04-2016 HRM2_RS19100 831b31aecc96f4147e1469f650cb4c32 1048 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 356 493 3.7E-10 T 22-04-2016 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 HRM2_RS19100 831b31aecc96f4147e1469f650cb4c32 1048 SMART SM00839 665 955 3.8E-5 T 22-04-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 HRM2_RS19100 831b31aecc96f4147e1469f650cb4c32 1048 Gene3D G3DSA:3.40.50.720 807 924 1.6E-25 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS19100 831b31aecc96f4147e1469f650cb4c32 1048 Gene3D G3DSA:3.40.50.720 665 769 1.6E-25 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS19100 831b31aecc96f4147e1469f650cb4c32 1048 PANTHER PTHR11606:SF9 666 1028 9.2E-83 T 22-04-2016 HRM2_RS19100 831b31aecc96f4147e1469f650cb4c32 1048 PANTHER PTHR11606:SF9 435 619 9.2E-83 T 22-04-2016 HRM2_RS19100 831b31aecc96f4147e1469f650cb4c32 1048 SUPERFAMILY SSF53223 435 622 6.19E-5 T 22-04-2016 HRM2_RS20025 fb2b58ff605858b5d17f65ec0d72690e 245 Pfam PF01966 HD domain 99 202 2.7E-10 T 22-04-2016 IPR006674 HD domain HRM2_RS20025 fb2b58ff605858b5d17f65ec0d72690e 245 SMART SM00471 95 214 0.0012 T 22-04-2016 IPR003607 HD/PDEase domain HRM2_RS20025 fb2b58ff605858b5d17f65ec0d72690e 245 SUPERFAMILY SSF109604 84 205 9.71E-25 T 22-04-2016 HRM2_RS20025 fb2b58ff605858b5d17f65ec0d72690e 245 Gene3D G3DSA:1.10.3210.10 81 203 2.0E-20 T 22-04-2016 IPR006674 HD domain HRM2_RS20625 cb7c94da02ac7102b1ae2daab6379efe 631 Gene3D G3DSA:3.30.450.20 66 135 1.9E-4 T 22-04-2016 HRM2_RS20625 cb7c94da02ac7102b1ae2daab6379efe 631 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 521 623 6.0E-21 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS20625 cb7c94da02ac7102b1ae2daab6379efe 631 SUPERFAMILY SSF47384 405 474 1.63E-13 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS20625 cb7c94da02ac7102b1ae2daab6379efe 631 SUPERFAMILY SSF103190 43 144 1.92E-8 T 22-04-2016 IPR029151 Periplasmic sensor domain-like HRM2_RS20625 cb7c94da02ac7102b1ae2daab6379efe 631 PANTHER PTHR24423 284 623 5.3E-80 T 22-04-2016 HRM2_RS20625 cb7c94da02ac7102b1ae2daab6379efe 631 Gene3D G3DSA:3.30.450.20 298 407 4.9E-7 T 22-04-2016 HRM2_RS20625 cb7c94da02ac7102b1ae2daab6379efe 631 Pfam PF00512 His Kinase A (phospho-acceptor) domain 414 474 2.7E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS20625 cb7c94da02ac7102b1ae2daab6379efe 631 SUPERFAMILY SSF55874 468 626 1.3E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS20625 cb7c94da02ac7102b1ae2daab6379efe 631 PRINTS PR00344 Bacterial sensor protein C-terminal signature 586 604 1.9E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS20625 cb7c94da02ac7102b1ae2daab6379efe 631 PRINTS PR00344 Bacterial sensor protein C-terminal signature 610 623 1.9E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS20625 cb7c94da02ac7102b1ae2daab6379efe 631 PRINTS PR00344 Bacterial sensor protein C-terminal signature 575 585 1.9E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS20625 cb7c94da02ac7102b1ae2daab6379efe 631 PRINTS PR00344 Bacterial sensor protein C-terminal signature 557 571 1.9E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HRM2_RS20625 cb7c94da02ac7102b1ae2daab6379efe 631 SMART SM00388 412 478 4.6E-13 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS20625 cb7c94da02ac7102b1ae2daab6379efe 631 SMART SM00387 520 626 2.9E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS20625 cb7c94da02ac7102b1ae2daab6379efe 631 SUPERFAMILY SSF55785 288 395 1.55E-8 T 22-04-2016 IPR000014 PAS domain HRM2_RS20625 cb7c94da02ac7102b1ae2daab6379efe 631 Gene3D G3DSA:1.10.287.130 408 463 2.4E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HRM2_RS20625 cb7c94da02ac7102b1ae2daab6379efe 631 PANTHER PTHR24423:SF445 284 623 5.3E-80 T 22-04-2016 HRM2_RS20625 cb7c94da02ac7102b1ae2daab6379efe 631 Gene3D G3DSA:3.30.565.10 464 627 5.1E-41 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS10560 42f2c0fb9152d860d0fc26fcf5cf7228 314 Pfam PF00682 HMGL-like 2 272 9.6E-46 T 22-04-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 HRM2_RS10560 42f2c0fb9152d860d0fc26fcf5cf7228 314 Gene3D G3DSA:3.20.20.70 2 278 7.3E-74 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS10560 42f2c0fb9152d860d0fc26fcf5cf7228 314 SUPERFAMILY SSF51569 2 278 2.2E-62 T 22-04-2016 HRM2_RS10560 42f2c0fb9152d860d0fc26fcf5cf7228 314 PANTHER PTHR10277 1 279 3.3E-127 T 22-04-2016 HRM2_RS10560 42f2c0fb9152d860d0fc26fcf5cf7228 314 PANTHER PTHR10277:SF1 1 279 3.3E-127 T 22-04-2016 HRM2_RS15290 c2a568d333861926393b5c903fed27e5 185 Pfam PF09936 SAM-dependent RNA methyltransferase 4 182 1.4E-70 T 22-04-2016 IPR019230 RNA methyltransferase domain HRM2_RS15290 c2a568d333861926393b5c903fed27e5 185 Gene3D G3DSA:3.40.1280.10 2 183 1.2E-70 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HRM2_RS21155 28e430f9a4a497b643b675c0b6f6f3e8 394 SUPERFAMILY SSF47090 329 391 4.19E-12 T 22-04-2016 IPR002477 Peptidoglycan binding-like HRM2_RS21155 28e430f9a4a497b643b675c0b6f6f3e8 394 Gene3D G3DSA:1.10.101.10 337 392 3.6E-10 T 22-04-2016 IPR002477 Peptidoglycan binding-like HRM2_RS21155 28e430f9a4a497b643b675c0b6f6f3e8 394 Pfam PF01471 Putative peptidoglycan binding domain 339 390 2.2E-10 T 22-04-2016 IPR002477 Peptidoglycan binding-like HRM2_RS07225 babd967458d5eae009777551faf95b0b 186 PANTHER PTHR41247 14 176 5.2E-14 T 22-04-2016 HRM2_RS07225 babd967458d5eae009777551faf95b0b 186 SUPERFAMILY SSF160387 74 171 5.75E-17 T 22-04-2016 HRM2_RS07225 babd967458d5eae009777551faf95b0b 186 Pfam PF05573 NosL 46 164 7.8E-18 T 22-04-2016 IPR008719 Nitrous oxide reductase accessory protein NosL HRM2_RS17065 f6f30d8841b040d8ee6b536e7662d2a7 77 Gene3D G3DSA:1.25.40.10 5 63 1.6E-11 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS17065 f6f30d8841b040d8ee6b536e7662d2a7 77 SMART SM00028 30 63 0.0011 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS17065 f6f30d8841b040d8ee6b536e7662d2a7 77 Pfam PF13424 Tetratricopeptide repeat 5 62 3.1E-8 T 22-04-2016 HRM2_RS17065 f6f30d8841b040d8ee6b536e7662d2a7 77 SUPERFAMILY SSF48452 5 65 7.49E-11 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS17530 4b8f9f5cf1d34d0ef452c65aec250dfd 283 PANTHER PTHR22911 9 280 2.2E-43 T 22-04-2016 HRM2_RS17530 4b8f9f5cf1d34d0ef452c65aec250dfd 283 SUPERFAMILY SSF103481 35 133 2.09E-9 T 22-04-2016 HRM2_RS17530 4b8f9f5cf1d34d0ef452c65aec250dfd 283 SUPERFAMILY SSF103481 179 280 2.35E-13 T 22-04-2016 HRM2_RS17530 4b8f9f5cf1d34d0ef452c65aec250dfd 283 Pfam PF00892 EamA-like transporter family 145 276 4.4E-18 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS17530 4b8f9f5cf1d34d0ef452c65aec250dfd 283 Pfam PF00892 EamA-like transporter family 7 133 3.5E-11 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS16570 c8851bc9048f6d6adf46c086cb8ab1c8 385 SUPERFAMILY SSF103473 8 381 6.02E-35 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS16570 c8851bc9048f6d6adf46c086cb8ab1c8 385 Gene3D G3DSA:1.20.1250.20 202 383 2.4E-22 T 22-04-2016 HRM2_RS16570 c8851bc9048f6d6adf46c086cb8ab1c8 385 Gene3D G3DSA:1.20.1250.20 10 189 4.6E-11 T 22-04-2016 HRM2_RS16570 c8851bc9048f6d6adf46c086cb8ab1c8 385 Pfam PF07690 Major Facilitator Superfamily 21 301 2.1E-12 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS08885 1b6d79fa694f786355c1bc575d705e71 134 Pfam PF03899 ATP synthase I chain 13 111 1.2E-11 T 22-04-2016 IPR005598 ATP synthase protein I HRM2_RS22315 1ebb03dae85cd7d4e8722e7fcd22bf31 441 Pfam PF00990 Diguanylate cyclase, GGDEF domain 278 437 2.6E-44 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS22315 1ebb03dae85cd7d4e8722e7fcd22bf31 441 PANTHER PTHR10799:SF728 1 438 1.5E-17 T 22-04-2016 HRM2_RS22315 1ebb03dae85cd7d4e8722e7fcd22bf31 441 Gene3D G3DSA:3.30.70.270 278 439 1.8E-46 T 22-04-2016 HRM2_RS22315 1ebb03dae85cd7d4e8722e7fcd22bf31 441 SMART SM00267 265 441 5.8E-53 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS22315 1ebb03dae85cd7d4e8722e7fcd22bf31 441 PANTHER PTHR10799 1 438 1.5E-17 T 22-04-2016 HRM2_RS22315 1ebb03dae85cd7d4e8722e7fcd22bf31 441 SUPERFAMILY SSF55073 281 439 4.0E-43 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS22315 1ebb03dae85cd7d4e8722e7fcd22bf31 441 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 275 440 5.0E-46 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS17855 3e6c935b9150897ee1ddec9c3d49fa99 85 Pfam PF00366 Ribosomal protein S17 12 78 1.1E-31 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17855 3e6c935b9150897ee1ddec9c3d49fa99 85 ProSitePatterns PS00056 Ribosomal protein S17 signature. 58 70 - T 22-04-2016 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17855 3e6c935b9150897ee1ddec9c3d49fa99 85 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 7 77 4.0E-34 T 22-04-2016 IPR019984 Ribosomal protein S17, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17855 3e6c935b9150897ee1ddec9c3d49fa99 85 Gene3D G3DSA:2.40.50.140 6 84 1.8E-34 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS17855 3e6c935b9150897ee1ddec9c3d49fa99 85 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 5 83 23.898 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17855 3e6c935b9150897ee1ddec9c3d49fa99 85 SUPERFAMILY SSF50249 6 84 6.43E-32 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS17855 3e6c935b9150897ee1ddec9c3d49fa99 85 PRINTS PR00973 Ribosomal protein S17 family signature 68 75 1.4E-12 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17855 3e6c935b9150897ee1ddec9c3d49fa99 85 PRINTS PR00973 Ribosomal protein S17 family signature 58 68 1.4E-12 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17855 3e6c935b9150897ee1ddec9c3d49fa99 85 PRINTS PR00973 Ribosomal protein S17 family signature 26 49 1.4E-12 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17855 3e6c935b9150897ee1ddec9c3d49fa99 85 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 6 77 4.0E-20 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17855 3e6c935b9150897ee1ddec9c3d49fa99 85 PANTHER PTHR10744 2 85 1.4E-39 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS23480 3dc67f75abb1ce57014ce67a7f25311c 335 PANTHER PTHR33376 1 335 1.4E-77 T 22-04-2016 HRM2_RS23480 3dc67f75abb1ce57014ce67a7f25311c 335 PIRSF PIRSF006470 1 333 1.5E-83 T 22-04-2016 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 HRM2_RS23480 3dc67f75abb1ce57014ce67a7f25311c 335 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 38 286 5.3E-73 T 22-04-2016 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 HRM2_RS23480 3dc67f75abb1ce57014ce67a7f25311c 335 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 38 317 4.3E-80 T 22-04-2016 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 HRM2_RS08535 6990e0e565a720f5286b2e7f8882ed4b 382 PANTHER PTHR30525 2 382 2.6E-194 T 22-04-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 HRM2_RS08535 6990e0e565a720f5286b2e7f8882ed4b 382 Pfam PF13288 DXP reductoisomerase C-terminal domain 260 376 3.8E-36 T 22-04-2016 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 HRM2_RS08535 6990e0e565a720f5286b2e7f8882ed4b 382 SUPERFAMILY SSF51735 2 149 1.1E-39 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS08535 6990e0e565a720f5286b2e7f8882ed4b 382 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 381 43.992 T 22-04-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 HRM2_RS08535 6990e0e565a720f5286b2e7f8882ed4b 382 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2 379 8.5E-140 T 22-04-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 HRM2_RS08535 6990e0e565a720f5286b2e7f8882ed4b 382 Gene3D G3DSA:3.40.50.720 2 149 1.2E-50 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS08535 6990e0e565a720f5286b2e7f8882ed4b 382 SUPERFAMILY SSF69055 291 381 7.06E-28 T 22-04-2016 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 HRM2_RS08535 6990e0e565a720f5286b2e7f8882ed4b 382 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 5 131 1.2E-39 T 22-04-2016 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 HRM2_RS08535 6990e0e565a720f5286b2e7f8882ed4b 382 PIRSF PIRSF006205 1 382 1.0E-146 T 22-04-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 HRM2_RS08535 6990e0e565a720f5286b2e7f8882ed4b 382 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 145 228 9.0E-38 T 22-04-2016 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 HRM2_RS08535 6990e0e565a720f5286b2e7f8882ed4b 382 SUPERFAMILY SSF55347 125 263 1.34E-58 T 22-04-2016 HRM2_RS08535 6990e0e565a720f5286b2e7f8882ed4b 382 Gene3D G3DSA:1.10.1740.10 302 381 1.6E-27 T 22-04-2016 HRM2_RS02030 724b93247d1e62efeeac3ca5255cf597 347 Gene3D G3DSA:3.40.630.30 145 298 2.9E-30 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS02030 724b93247d1e62efeeac3ca5255cf597 347 SUPERFAMILY SSF55729 148 307 6.89E-30 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS02030 724b93247d1e62efeeac3ca5255cf597 347 Pfam PF13480 Acetyltransferase (GNAT) domain 159 283 2.1E-14 T 22-04-2016 HRM2_RS05125 a09e3404114e45ebe53b819fc04da522 396 Gene3D G3DSA:3.30.470.20 117 271 2.6E-7 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS05125 a09e3404114e45ebe53b819fc04da522 396 Pfam PF13535 ATP-grasp domain 122 279 1.0E-65 T 22-04-2016 HRM2_RS05125 a09e3404114e45ebe53b819fc04da522 396 SUPERFAMILY SSF56059 83 292 1.3E-19 T 22-04-2016 HRM2_RS16130 d9bca4555e01ffdbc9f4a6790745c97b 305 Pfam PF04909 Amidohydrolase 35 303 8.4E-29 T 22-04-2016 IPR006680 Amidohydrolase-related GO:0016787 HRM2_RS16130 d9bca4555e01ffdbc9f4a6790745c97b 305 SUPERFAMILY SSF51556 33 303 4.54E-50 T 22-04-2016 IPR032466 Metal-dependent hydrolase HRM2_RS16130 d9bca4555e01ffdbc9f4a6790745c97b 305 PANTHER PTHR21240:SF12 34 303 1.8E-20 T 22-04-2016 HRM2_RS16130 d9bca4555e01ffdbc9f4a6790745c97b 305 Gene3D G3DSA:3.20.20.140 33 304 8.5E-50 T 22-04-2016 HRM2_RS16130 d9bca4555e01ffdbc9f4a6790745c97b 305 PANTHER PTHR21240 34 303 1.8E-20 T 22-04-2016 HRM2_RS03490 18e20d1d5bf427169fe458f3ffcfe6a9 849 PANTHER PTHR22931 159 554 1.2E-47 T 22-04-2016 HRM2_RS03490 18e20d1d5bf427169fe458f3ffcfe6a9 849 PANTHER PTHR22931:SF7 159 554 1.2E-47 T 22-04-2016 HRM2_RS03490 18e20d1d5bf427169fe458f3ffcfe6a9 849 Gene3D G3DSA:3.30.470.20 309 448 5.0E-24 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS03490 18e20d1d5bf427169fe458f3ffcfe6a9 849 Pfam PF00391 PEP-utilising enzyme, mobile domain 478 547 3.5E-6 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS03490 18e20d1d5bf427169fe458f3ffcfe6a9 849 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 139 441 4.8E-56 T 22-04-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 HRM2_RS03490 18e20d1d5bf427169fe458f3ffcfe6a9 849 Gene3D G3DSA:3.30.1490.20 136 308 9.5E-36 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HRM2_RS03490 18e20d1d5bf427169fe458f3ffcfe6a9 849 SUPERFAMILY SSF52009 449 554 1.83E-12 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS03490 18e20d1d5bf427169fe458f3ffcfe6a9 849 Gene3D G3DSA:3.50.30.10 473 554 2.9E-10 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HRM2_RS03490 18e20d1d5bf427169fe458f3ffcfe6a9 849 SUPERFAMILY SSF56059 136 434 2.12E-48 T 22-04-2016 HRM2_RS22120 d7015207291d90e235a57df2a5aa51c0 279 Gene3D G3DSA:3.40.630.30 124 254 5.5E-13 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS22120 d7015207291d90e235a57df2a5aa51c0 279 TIGRFAM TIGR03827 GNAT_ablB: putative beta-lysine N-acetyltransferase 12 275 1.0E-97 T 22-04-2016 IPR022525 Beta-lysine N-acetyltransferase GO:0016407 KEGG: 00061+2.3.1.-|KEGG: 00253+2.3.1.-|KEGG: 00261+2.3.1.-|KEGG: 00310+2.3.1.-|KEGG: 00330+2.3.1.-|KEGG: 00332+2.3.1.-|KEGG: 00340+2.3.1.-|KEGG: 00350+2.3.1.-|KEGG: 00564+2.3.1.-|KEGG: 00565+2.3.1.-|KEGG: 00604+2.3.1.-|KEGG: 00623+2.3.1.-|KEGG: 00626+2.3.1.-|KEGG: 00627+2.3.1.-|KEGG: 00642+2.3.1.-|KEGG: 00650+2.3.1.-|KEGG: 00680+2.3.1.-|KEGG: 00903+2.3.1.-|KEGG: 00904+2.3.1.-|KEGG: 00906+2.3.1.-|KEGG: 00940+2.3.1.-|KEGG: 00942+2.3.1.-|KEGG: 00950+2.3.1.-|KEGG: 00960+2.3.1.-|KEGG: 00965+2.3.1.- HRM2_RS22120 d7015207291d90e235a57df2a5aa51c0 279 SUPERFAMILY SSF55729 118 257 2.57E-15 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS18905 cbaf7f7846e0fe36a6af2757d97c6c89 130 PANTHER PTHR31964 1 130 4.0E-15 T 22-04-2016 HRM2_RS18905 cbaf7f7846e0fe36a6af2757d97c6c89 130 Pfam PF00582 Universal stress protein family 2 130 8.2E-21 T 22-04-2016 IPR006016 UspA GO:0006950 HRM2_RS18905 cbaf7f7846e0fe36a6af2757d97c6c89 130 SUPERFAMILY SSF52402 2 130 1.26E-23 T 22-04-2016 HRM2_RS18905 cbaf7f7846e0fe36a6af2757d97c6c89 130 Gene3D G3DSA:3.40.50.620 2 130 1.1E-26 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS18905 cbaf7f7846e0fe36a6af2757d97c6c89 130 PRINTS PR01438 Universal stress protein signature 108 130 3.3E-7 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS18905 cbaf7f7846e0fe36a6af2757d97c6c89 130 PRINTS PR01438 Universal stress protein signature 90 102 3.3E-7 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS24300 36f463f69cca452d72d295031530fdbe 1476 Gene3D G3DSA:3.40.1140.10 38 102 1.1E-5 T 22-04-2016 HRM2_RS24300 36f463f69cca452d72d295031530fdbe 1476 Gene3D G3DSA:3.40.1140.10 1336 1405 1.1E-5 T 22-04-2016 HRM2_RS01300 1578388f198353c85c6714387064be6f 465 Gene3D G3DSA:1.10.3210.10 175 197 6.0E-12 T 22-04-2016 IPR006674 HD domain HRM2_RS01300 1578388f198353c85c6714387064be6f 465 Gene3D G3DSA:1.10.3210.10 236 348 6.0E-12 T 22-04-2016 IPR006674 HD domain HRM2_RS01300 1578388f198353c85c6714387064be6f 465 SUPERFAMILY SSF109604 237 376 4.0E-15 T 22-04-2016 HRM2_RS01300 1578388f198353c85c6714387064be6f 465 SMART SM00471 175 350 1.4E-6 T 22-04-2016 IPR003607 HD/PDEase domain HRM2_RS01300 1578388f198353c85c6714387064be6f 465 Pfam PF01966 HD domain 180 341 8.1E-11 T 22-04-2016 IPR006674 HD domain HRM2_RS18635 b9e150b9648b7b43380023096bad9048 328 SUPERFAMILY SSF53822 36 290 1.57E-12 T 22-04-2016 IPR028082 Periplasmic binding protein-like I HRM2_RS18635 b9e150b9648b7b43380023096bad9048 328 PANTHER PTHR35271 1 321 6.1E-57 T 22-04-2016 HRM2_RS18635 b9e150b9648b7b43380023096bad9048 328 Gene3D G3DSA:3.40.50.2300 28 150 2.0E-40 T 22-04-2016 HRM2_RS18635 b9e150b9648b7b43380023096bad9048 328 Pfam PF04392 ABC transporter substrate binding protein 30 318 8.1E-75 T 22-04-2016 IPR007487 ABC transporter, substrate-binding protein HRM2_RS18635 b9e150b9648b7b43380023096bad9048 328 Gene3D G3DSA:3.40.50.2300 151 282 3.1E-39 T 22-04-2016 HRM2_RS04470 25b6003687fda15c64e81e76fb1dc331 273 SUPERFAMILY SSF53850 23 262 8.0E-17 T 22-04-2016 HRM2_RS04470 25b6003687fda15c64e81e76fb1dc331 273 PANTHER PTHR30024 29 213 2.0E-14 T 22-04-2016 HRM2_RS04470 25b6003687fda15c64e81e76fb1dc331 273 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 31 266 7.9E-50 T 22-04-2016 HRM2_RS04470 25b6003687fda15c64e81e76fb1dc331 273 Gene3D G3DSA:3.40.190.10 116 198 7.7E-7 T 22-04-2016 HRM2_RS04470 25b6003687fda15c64e81e76fb1dc331 273 PANTHER PTHR30024:SF17 29 213 2.0E-14 T 22-04-2016 HRM2_RS05880 fd3e6ed6e2b18c6e1a2d38d85cf80bc6 135 PANTHER PTHR11615:SF112 8 135 9.7E-37 T 22-04-2016 HRM2_RS05880 fd3e6ed6e2b18c6e1a2d38d85cf80bc6 135 Gene3D G3DSA:2.20.25.90 3 57 8.9E-20 T 22-04-2016 HRM2_RS05880 fd3e6ed6e2b18c6e1a2d38d85cf80bc6 135 Pfam PF00384 Molybdopterin oxidoreductase 60 135 5.1E-14 T 22-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 HRM2_RS05880 fd3e6ed6e2b18c6e1a2d38d85cf80bc6 135 Gene3D G3DSA:3.40.50.740 60 132 7.1E-27 T 22-04-2016 HRM2_RS05880 fd3e6ed6e2b18c6e1a2d38d85cf80bc6 135 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 4 57 5.7E-18 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS05880 fd3e6ed6e2b18c6e1a2d38d85cf80bc6 135 SMART SM00926 3 57 9.5E-17 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 HRM2_RS05880 fd3e6ed6e2b18c6e1a2d38d85cf80bc6 135 PANTHER PTHR11615 8 135 9.7E-37 T 22-04-2016 HRM2_RS05880 fd3e6ed6e2b18c6e1a2d38d85cf80bc6 135 SUPERFAMILY SSF53706 2 135 7.46E-50 T 22-04-2016 HRM2_RS16790 0f1a070423da22a5bebf26d26b38492b 576 SUPERFAMILY SSF52540 241 422 1.11E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS16790 0f1a070423da22a5bebf26d26b38492b 576 PANTHER PTHR38149 1 573 1.1E-138 T 22-04-2016 HRM2_RS16790 0f1a070423da22a5bebf26d26b38492b 576 Pfam PF09818 Predicted ATPase of the ABC class 6 445 7.1E-177 T 22-04-2016 IPR019195 ABC transporter, ATPase, putative HRM2_RS16790 0f1a070423da22a5bebf26d26b38492b 576 Gene3D G3DSA:3.40.50.300 245 418 1.4E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17570 c0f6d9846d5ca079d1bb923dfe327200 111 Gene3D G3DSA:3.30.450.30 6 86 3.8E-4 T 22-04-2016 HRM2_RS18730 62a428709bcba887f2d34cb00b8089c5 379 Pfam PF04443 Acyl-protein synthetase, LuxE 11 367 4.4E-34 T 22-04-2016 IPR007534 Acyl-protein synthetase, LuxE GO:0008218|GO:0047474 MetaCyc: PWY-7723|UniPathway: UPA00569 HRM2_RS21025 d058b42a3e380cdf21af2fc296d92bc2 248 Pfam PF13852 Protein of unknown function (DUF4197) 49 246 1.3E-75 T 22-04-2016 IPR025245 Protein of unknown function DUF4197 HRM2_RS25360 c83d87e6e804b44c422e311e203519fe 388 Gene3D G3DSA:1.10.780.10 240 368 3.6E-15 T 22-04-2016 HRM2_RS25360 c83d87e6e804b44c422e311e203519fe 388 Pfam PF13435 Cytochrome c554 and c-prime 263 336 5.3E-15 T 22-04-2016 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674|UniPathway: UPA00653 HRM2_RS25360 c83d87e6e804b44c422e311e203519fe 388 SUPERFAMILY SSF48695 257 367 1.05E-19 T 22-04-2016 IPR011031 Multihaem cytochrome HRM2_RS25360 c83d87e6e804b44c422e311e203519fe 388 Gene3D G3DSA:3.60.21.10 2 239 6.9E-26 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS25360 c83d87e6e804b44c422e311e203519fe 388 SUPERFAMILY SSF56300 5 240 9.86E-31 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS13525 6357851d2f0a1701b6678a618dfcd7bc 347 SUPERFAMILY SSF161098 139 325 3.14E-19 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS13525 6357851d2f0a1701b6678a618dfcd7bc 347 Gene3D G3DSA:1.10.3720.10 136 340 4.7E-19 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS13525 6357851d2f0a1701b6678a618dfcd7bc 347 PANTHER PTHR30325 1 347 3.4E-111 T 22-04-2016 HRM2_RS13525 6357851d2f0a1701b6678a618dfcd7bc 347 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 161 343 3.9E-27 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS20525 8f6306ba498ef97efd7aa7f5c5799c1b 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 255 8.5E-57 T 22-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 HRM2_RS20525 8f6306ba498ef97efd7aa7f5c5799c1b 257 SUPERFAMILY SSF52096 3 255 1.12E-77 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS20525 8f6306ba498ef97efd7aa7f5c5799c1b 257 Gene3D G3DSA:3.90.226.10 3 251 6.6E-77 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS20525 8f6306ba498ef97efd7aa7f5c5799c1b 257 PANTHER PTHR11941 1 254 1.3E-80 T 22-04-2016 HRM2_RS03815 aea599df95d18ebc9ef2b2e145d9c45f 161 PRINTS PR01438 Universal stress protein signature 4 22 4.4E-15 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS03815 aea599df95d18ebc9ef2b2e145d9c45f 161 PRINTS PR01438 Universal stress protein signature 117 129 4.4E-15 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS03815 aea599df95d18ebc9ef2b2e145d9c45f 161 PRINTS PR01438 Universal stress protein signature 135 157 4.4E-15 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS03815 aea599df95d18ebc9ef2b2e145d9c45f 161 PANTHER PTHR31964 1 161 7.1E-24 T 22-04-2016 HRM2_RS03815 aea599df95d18ebc9ef2b2e145d9c45f 161 PIRSF PIRSF006276 1 160 2.5E-18 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS03815 aea599df95d18ebc9ef2b2e145d9c45f 161 SUPERFAMILY SSF52402 3 158 1.4E-28 T 22-04-2016 HRM2_RS03815 aea599df95d18ebc9ef2b2e145d9c45f 161 Pfam PF00582 Universal stress protein family 4 157 1.7E-26 T 22-04-2016 IPR006016 UspA GO:0006950 HRM2_RS03815 aea599df95d18ebc9ef2b2e145d9c45f 161 Gene3D G3DSA:3.40.50.620 2 158 2.7E-31 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS24220 f7bd0d5c40802c5edd7fb06babaaa6d0 368 Pfam PF06114 Domain of unknown function (DUF955) 244 305 7.2E-7 T 22-04-2016 IPR010359 HTH domain, IrrE-type HRM2_RS24220 f7bd0d5c40802c5edd7fb06babaaa6d0 368 Pfam PF01381 Helix-turn-helix 29 74 9.4E-9 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS24220 f7bd0d5c40802c5edd7fb06babaaa6d0 368 SMART SM00530 21 76 2.2E-7 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS24220 f7bd0d5c40802c5edd7fb06babaaa6d0 368 Gene3D G3DSA:1.10.260.40 12 86 1.2E-21 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS24220 f7bd0d5c40802c5edd7fb06babaaa6d0 368 SUPERFAMILY SSF47413 18 89 2.82E-18 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS00750 9f23b56231fe0d54279947e4d53a79eb 179 SUPERFAMILY SSF54862 2 173 3.93E-38 T 22-04-2016 HRM2_RS00750 9f23b56231fe0d54279947e4d53a79eb 179 PANTHER PTHR11938 126 157 2.0E-34 T 22-04-2016 HRM2_RS00750 9f23b56231fe0d54279947e4d53a79eb 179 PANTHER PTHR11938 1 107 2.0E-34 T 22-04-2016 HRM2_RS00750 9f23b56231fe0d54279947e4d53a79eb 179 Pfam PF13247 4Fe-4S dicluster domain 53 106 4.0E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS00750 9f23b56231fe0d54279947e4d53a79eb 179 PANTHER PTHR11938:SF111 126 157 2.0E-34 T 22-04-2016 HRM2_RS00750 9f23b56231fe0d54279947e4d53a79eb 179 PANTHER PTHR11938:SF111 1 107 2.0E-34 T 22-04-2016 HRM2_RS00750 9f23b56231fe0d54279947e4d53a79eb 179 Pfam PF12798 4Fe-4S binding domain 136 153 0.084 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS00750 9f23b56231fe0d54279947e4d53a79eb 179 Gene3D G3DSA:3.30.70.20 69 95 3.1E-16 T 22-04-2016 HRM2_RS00750 9f23b56231fe0d54279947e4d53a79eb 179 Gene3D G3DSA:3.30.70.20 96 173 2.3E-16 T 22-04-2016 HRM2_RS00750 9f23b56231fe0d54279947e4d53a79eb 179 Gene3D G3DSA:3.30.70.20 8 68 5.3E-10 T 22-04-2016 HRM2_RS00750 9f23b56231fe0d54279947e4d53a79eb 179 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 88 99 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS00700 616676f8002df5c52d22d0c415989b43 411 SUPERFAMILY SSF103473 11 410 2.49E-49 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS00700 616676f8002df5c52d22d0c415989b43 411 Gene3D G3DSA:1.20.1250.20 209 405 3.5E-13 T 22-04-2016 HRM2_RS00700 616676f8002df5c52d22d0c415989b43 411 PANTHER PTHR23501 6 411 1.4E-24 T 22-04-2016 HRM2_RS00700 616676f8002df5c52d22d0c415989b43 411 Pfam PF07690 Major Facilitator Superfamily 18 324 2.2E-29 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS00700 616676f8002df5c52d22d0c415989b43 411 Gene3D G3DSA:1.20.1250.20 13 197 2.5E-24 T 22-04-2016 HRM2_RS10110 f88e6b58a58e1a90412d3a3199620a4d 440 PANTHER PTHR32479:SF13 15 414 3.5E-61 T 22-04-2016 HRM2_RS10110 f88e6b58a58e1a90412d3a3199620a4d 440 PIRSF PIRSF000139 4 436 5.0E-76 T 22-04-2016 IPR012257 Glycolate oxidase, iron-sulphur subunit HRM2_RS10110 f88e6b58a58e1a90412d3a3199620a4d 440 Pfam PF13183 4Fe-4S dicluster domain 23 88 6.4E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS10110 f88e6b58a58e1a90412d3a3199620a4d 440 Gene3D G3DSA:1.10.1060.10 19 104 1.2E-12 T 22-04-2016 HRM2_RS10110 f88e6b58a58e1a90412d3a3199620a4d 440 Pfam PF02754 Cysteine-rich domain 324 408 3.3E-12 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS10110 f88e6b58a58e1a90412d3a3199620a4d 440 Pfam PF02754 Cysteine-rich domain 187 271 4.1E-9 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS10110 f88e6b58a58e1a90412d3a3199620a4d 440 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 25 36 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS10110 f88e6b58a58e1a90412d3a3199620a4d 440 PANTHER PTHR32479 15 414 3.5E-61 T 22-04-2016 HRM2_RS10110 f88e6b58a58e1a90412d3a3199620a4d 440 SUPERFAMILY SSF46548 21 104 2.04E-13 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS06055 c015db7ea46f2f5bfbb872f78503040a 175 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 35 161 1.7E-23 T 22-04-2016 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component HRM2_RS06055 c015db7ea46f2f5bfbb872f78503040a 175 PANTHER PTHR35011 1 161 2.6E-16 T 22-04-2016 HRM2_RS09530 fd60e95af01e2aa7983c275eb9759776 88 SUPERFAMILY SSF47413 1 52 4.35E-12 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS09530 fd60e95af01e2aa7983c275eb9759776 88 SMART SM00530 1 46 8.7E-4 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS09530 fd60e95af01e2aa7983c275eb9759776 88 Gene3D G3DSA:1.10.260.40 1 70 1.6E-14 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS09530 fd60e95af01e2aa7983c275eb9759776 88 Pfam PF01381 Helix-turn-helix 1 44 2.3E-11 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS06770 7b2a4170dad8f565442a35811c6ba7aa 478 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 334 448 3.1E-14 T 22-04-2016 IPR003390 DNA integrity scanning protein, DisA, N-terminal HRM2_RS06770 7b2a4170dad8f565442a35811c6ba7aa 478 Gene3D G3DSA:3.40.1700.10 330 448 3.6E-6 T 22-04-2016 HRM2_RS06770 7b2a4170dad8f565442a35811c6ba7aa 478 SUPERFAMILY SSF143597 315 449 3.79E-11 T 22-04-2016 HRM2_RS02710 402e5f1a98ef489e92f6cbda73766b48 516 Pfam PF09484 CRISPR-associated protein TM1802 (cas_TM1802) 219 516 5.0E-13 T 22-04-2016 IPR013389 CRISPR-associated protein TM1802 HRM2_RS04835 ca905831ba09205e2a8251e88a3e893f 308 PANTHER PTHR16222 12 293 3.7E-63 T 22-04-2016 HRM2_RS04835 ca905831ba09205e2a8251e88a3e893f 308 SUPERFAMILY SSF101478 12 295 1.2E-74 T 22-04-2016 IPR005502 ADP-ribosylation/Crystallin J1 HRM2_RS04835 ca905831ba09205e2a8251e88a3e893f 308 Pfam PF03747 ADP-ribosylglycohydrolase 18 273 1.1E-57 T 22-04-2016 IPR005502 ADP-ribosylation/Crystallin J1 HRM2_RS04835 ca905831ba09205e2a8251e88a3e893f 308 TIGRFAM TIGR02662 dinitro_DRAG: ADP-ribosyl-[dinitrogen reductase] hydrolase 12 297 1.2E-128 T 22-04-2016 IPR013479 ADP-ribosyl-dinitrogen reductase hydrolase HRM2_RS04835 ca905831ba09205e2a8251e88a3e893f 308 PANTHER PTHR16222:SF12 12 293 3.7E-63 T 22-04-2016 HRM2_RS11025 960d4d3f1b31c6a0f912a3d7cae390d6 309 PANTHER PTHR10120:SF19 3 299 9.8E-104 T 22-04-2016 HRM2_RS11025 960d4d3f1b31c6a0f912a3d7cae390d6 309 Pfam PF01435 Peptidase family M48 70 279 4.0E-34 T 22-04-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 HRM2_RS11025 960d4d3f1b31c6a0f912a3d7cae390d6 309 Hamap MF_00188 Protease HtpX [htpX]. 4 280 29.463 T 22-04-2016 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 HRM2_RS11025 960d4d3f1b31c6a0f912a3d7cae390d6 309 PANTHER PTHR10120 3 299 9.8E-104 T 22-04-2016 HRM2_RS11025 960d4d3f1b31c6a0f912a3d7cae390d6 309 Gene3D G3DSA:3.30.2010.10 57 147 2.1E-34 T 22-04-2016 HRM2_RS23130 789a6d1b22b49bb02ef2d4a4d8ee8be5 276 Pfam PF02915 Rubrerythrin 129 272 2.9E-12 T 22-04-2016 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 HRM2_RS23130 789a6d1b22b49bb02ef2d4a4d8ee8be5 276 SUPERFAMILY SSF52821 8 107 3.4E-28 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS23130 789a6d1b22b49bb02ef2d4a4d8ee8be5 276 Gene3D G3DSA:3.40.250.10 7 108 2.8E-27 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS23130 789a6d1b22b49bb02ef2d4a4d8ee8be5 276 SMART SM00450 16 111 2.8E-19 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS23130 789a6d1b22b49bb02ef2d4a4d8ee8be5 276 SUPERFAMILY SSF47240 126 276 2.31E-23 T 22-04-2016 IPR009078 Ferritin-like superfamily HRM2_RS23130 789a6d1b22b49bb02ef2d4a4d8ee8be5 276 Gene3D G3DSA:1.20.1260.10 116 275 2.1E-32 T 22-04-2016 IPR012347 Ferritin-related HRM2_RS23130 789a6d1b22b49bb02ef2d4a4d8ee8be5 276 Pfam PF00581 Rhodanese-like domain 29 107 8.0E-16 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS23130 789a6d1b22b49bb02ef2d4a4d8ee8be5 276 PANTHER PTHR12231:SF91 27 146 1.9E-16 T 22-04-2016 HRM2_RS23130 789a6d1b22b49bb02ef2d4a4d8ee8be5 276 PANTHER PTHR12231 27 146 1.9E-16 T 22-04-2016 HRM2_RS23130 789a6d1b22b49bb02ef2d4a4d8ee8be5 276 ProSitePatterns PS00380 Rhodanese signature 1. 41 52 - T 22-04-2016 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 HRM2_RS23120 62d15dc93bfddc44be79ad6e40ec4235 305 Gene3D G3DSA:2.40.50.100 131 235 6.6E-24 T 22-04-2016 HRM2_RS23120 62d15dc93bfddc44be79ad6e40ec4235 305 Pfam PF01597 Glycine cleavage H-protein 133 234 2.6E-20 T 22-04-2016 IPR002930 Glycine cleavage system H-protein HRM2_RS23120 62d15dc93bfddc44be79ad6e40ec4235 305 SUPERFAMILY SSF51230 128 233 1.67E-23 T 22-04-2016 IPR011053 Single hybrid motif HRM2_RS23120 62d15dc93bfddc44be79ad6e40ec4235 305 PANTHER PTHR11715:SF12 81 230 3.3E-17 T 22-04-2016 HRM2_RS23120 62d15dc93bfddc44be79ad6e40ec4235 305 PANTHER PTHR11715 81 230 3.3E-17 T 22-04-2016 IPR002930 Glycine cleavage system H-protein HRM2_RS08830 99cd4577dc5b2637d36c3c6c5e9e902c 502 Gene3D G3DSA:3.80.30.20 251 416 1.8E-16 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe HRM2_RS08830 99cd4577dc5b2637d36c3c6c5e9e902c 502 PANTHER PTHR11918:SF47 4 425 2.1E-56 T 22-04-2016 HRM2_RS08830 99cd4577dc5b2637d36c3c6c5e9e902c 502 SUPERFAMILY SSF102114 223 423 2.22E-22 T 22-04-2016 HRM2_RS08830 99cd4577dc5b2637d36c3c6c5e9e902c 502 PANTHER PTHR11918 4 425 2.1E-56 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein HRM2_RS08830 99cd4577dc5b2637d36c3c6c5e9e902c 502 SMART SM00729 250 442 1.3E-10 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS05070 659579c8940651e147e028540354a67a 334 SUPERFAMILY SSF46565 272 331 4.32E-10 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS05070 659579c8940651e147e028540354a67a 334 SMART SM00271 276 334 0.0086 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS05070 659579c8940651e147e028540354a67a 334 Gene3D G3DSA:1.10.287.110 276 329 3.6E-10 T 22-04-2016 IPR001623 DnaJ domain HRM2_RS10480 bbf27668ae92a8817f12672fe6592fe9 416 SUPERFAMILY SSF56954 88 408 4.32E-11 T 22-04-2016 HRM2_RS10480 bbf27668ae92a8817f12672fe6592fe9 416 Gene3D G3DSA:1.20.1600.10 106 350 1.8E-4 T 22-04-2016 HRM2_RS13750 30be2479decbe4a1c934b30270cd6af1 312 Gene3D G3DSA:3.40.50.1370 148 290 1.8E-47 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HRM2_RS13750 30be2479decbe4a1c934b30270cd6af1 312 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 52 59 - T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HRM2_RS13750 30be2479decbe4a1c934b30270cd6af1 312 Gene3D G3DSA:3.40.50.1370 6 147 8.4E-49 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HRM2_RS13750 30be2479decbe4a1c934b30270cd6af1 312 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 155 301 9.5E-28 T 22-04-2016 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 HRM2_RS13750 30be2479decbe4a1c934b30270cd6af1 312 SUPERFAMILY SSF53671 3 305 5.89E-96 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HRM2_RS13750 30be2479decbe4a1c934b30270cd6af1 312 PRINTS PR00101 Aspartate carbamoyltransferase signature 219 228 3.2E-30 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 HRM2_RS13750 30be2479decbe4a1c934b30270cd6af1 312 PRINTS PR00101 Aspartate carbamoyltransferase signature 260 265 3.2E-30 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 HRM2_RS13750 30be2479decbe4a1c934b30270cd6af1 312 PRINTS PR00101 Aspartate carbamoyltransferase signature 135 152 3.2E-30 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 HRM2_RS13750 30be2479decbe4a1c934b30270cd6af1 312 PRINTS PR00101 Aspartate carbamoyltransferase signature 80 89 3.2E-30 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 HRM2_RS13750 30be2479decbe4a1c934b30270cd6af1 312 PRINTS PR00101 Aspartate carbamoyltransferase signature 42 64 3.2E-30 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 HRM2_RS13750 30be2479decbe4a1c934b30270cd6af1 312 PRINTS PR00101 Aspartate carbamoyltransferase signature 284 298 3.2E-30 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 HRM2_RS13750 30be2479decbe4a1c934b30270cd6af1 312 PANTHER PTHR11405:SF16 1 305 5.1E-126 T 22-04-2016 HRM2_RS13750 30be2479decbe4a1c934b30270cd6af1 312 PANTHER PTHR11405 1 305 5.1E-126 T 22-04-2016 HRM2_RS13750 30be2479decbe4a1c934b30270cd6af1 312 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 5 305 39.6 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 HRM2_RS13750 30be2479decbe4a1c934b30270cd6af1 312 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 6 149 1.0E-38 T 22-04-2016 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 HRM2_RS13750 30be2479decbe4a1c934b30270cd6af1 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 52 71 4.7E-19 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HRM2_RS13750 30be2479decbe4a1c934b30270cd6af1 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 136 147 4.7E-19 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HRM2_RS13750 30be2479decbe4a1c934b30270cd6af1 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 268 291 4.7E-19 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HRM2_RS13750 30be2479decbe4a1c934b30270cd6af1 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 256 265 4.7E-19 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HRM2_RS13750 30be2479decbe4a1c934b30270cd6af1 312 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 6 302 2.9E-93 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 HRM2_RS07705 6d9d9aac47fb519aac4d74b5ba0d729c 291 SUPERFAMILY SSF53613 5 279 3.74E-63 T 22-04-2016 IPR029056 Ribokinase-like HRM2_RS07705 6d9d9aac47fb519aac4d74b5ba0d729c 291 Gene3D G3DSA:3.40.1190.20 4 274 7.0E-61 T 22-04-2016 IPR029056 Ribokinase-like HRM2_RS07705 6d9d9aac47fb519aac4d74b5ba0d729c 291 PANTHER PTHR10534 1 275 1.7E-78 T 22-04-2016 IPR004625 Pyridoxine kinase GO:0008478|GO:0009443 KEGG: 00750+2.7.1.35|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 HRM2_RS07705 6d9d9aac47fb519aac4d74b5ba0d729c 291 Pfam PF08543 Phosphomethylpyrimidine kinase 30 261 1.1E-25 T 22-04-2016 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase UniPathway: UPA00647 HRM2_RS07705 6d9d9aac47fb519aac4d74b5ba0d729c 291 PANTHER PTHR10534:SF0 1 275 1.7E-78 T 22-04-2016 HRM2_RS24985 b0f72fa946f2df13a1d23bb788d7d832 354 SUPERFAMILY SSF56645 3 225 3.14E-45 T 22-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 HRM2_RS24985 b0f72fa946f2df13a1d23bb788d7d832 354 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 114 2.4E-14 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS24985 b0f72fa946f2df13a1d23bb788d7d832 354 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 118 213 9.6E-17 T 22-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 HRM2_RS24985 b0f72fa946f2df13a1d23bb788d7d832 354 PANTHER PTHR10909:SF305 4 225 8.9E-33 T 22-04-2016 HRM2_RS24985 b0f72fa946f2df13a1d23bb788d7d832 354 PANTHER PTHR10909 4 225 8.9E-33 T 22-04-2016 HRM2_RS24985 b0f72fa946f2df13a1d23bb788d7d832 354 Gene3D G3DSA:2.40.110.10 118 225 9.5E-22 T 22-04-2016 HRM2_RS24985 b0f72fa946f2df13a1d23bb788d7d832 354 Gene3D G3DSA:1.10.540.10 4 114 9.1E-18 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS16165 e3a111b52217d710a3aa30c717ba59ac 175 Pfam PF00881 Nitroreductase family 64 150 1.1E-9 T 22-04-2016 IPR029479 Nitroreductase HRM2_RS16165 e3a111b52217d710a3aa30c717ba59ac 175 Pfam PF00881 Nitroreductase family 7 58 8.5E-13 T 22-04-2016 IPR029479 Nitroreductase HRM2_RS16165 e3a111b52217d710a3aa30c717ba59ac 175 PANTHER PTHR23026 2 175 6.6E-60 T 22-04-2016 HRM2_RS16165 e3a111b52217d710a3aa30c717ba59ac 175 Gene3D G3DSA:3.40.109.10 2 174 1.1E-50 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 HRM2_RS16165 e3a111b52217d710a3aa30c717ba59ac 175 SUPERFAMILY SSF55469 2 173 5.23E-45 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 HRM2_RS16165 e3a111b52217d710a3aa30c717ba59ac 175 PANTHER PTHR23026:SF117 2 175 6.6E-60 T 22-04-2016 HRM2_RS08565 694d1d0ddfd275fb1f2876b3ab4a7999 141 PANTHER PTHR23091 1 131 4.7E-23 T 22-04-2016 HRM2_RS08565 694d1d0ddfd275fb1f2876b3ab4a7999 141 SUPERFAMILY SSF55729 1 129 2.33E-26 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS08565 694d1d0ddfd275fb1f2876b3ab4a7999 141 Pfam PF00583 Acetyltransferase (GNAT) family 52 126 2.5E-16 T 22-04-2016 IPR000182 GNAT domain GO:0008080 HRM2_RS08565 694d1d0ddfd275fb1f2876b3ab4a7999 141 Gene3D G3DSA:3.40.630.30 1 125 8.2E-26 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS14105 61625ee53d3e1b4efd79f1002f0b5d82 232 SUPERFAMILY SSF52540 5 227 6.66E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14105 61625ee53d3e1b4efd79f1002f0b5d82 232 PANTHER PTHR24220 7 229 7.8E-73 T 22-04-2016 HRM2_RS14105 61625ee53d3e1b4efd79f1002f0b5d82 232 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS14105 61625ee53d3e1b4efd79f1002f0b5d82 232 Pfam PF00005 ABC transporter 24 185 3.3E-27 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS14105 61625ee53d3e1b4efd79f1002f0b5d82 232 PANTHER PTHR24220:SF585 7 229 7.8E-73 T 22-04-2016 HRM2_RS14105 61625ee53d3e1b4efd79f1002f0b5d82 232 SMART SM00382 30 232 1.6E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS14105 61625ee53d3e1b4efd79f1002f0b5d82 232 Gene3D G3DSA:3.40.50.300 4 226 2.1E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00740 5c40af96c25f67c7f555929c1e0dea8e 319 Pfam PF09084 NMT1/THI5 like 60 249 1.9E-9 T 22-04-2016 IPR015168 SsuA/THI5-like HRM2_RS00740 5c40af96c25f67c7f555929c1e0dea8e 319 PANTHER PTHR30024 1 274 2.6E-17 T 22-04-2016 HRM2_RS00740 5c40af96c25f67c7f555929c1e0dea8e 319 Gene3D G3DSA:3.40.190.10 124 235 7.8E-9 T 22-04-2016 HRM2_RS00740 5c40af96c25f67c7f555929c1e0dea8e 319 SUPERFAMILY SSF53850 33 254 2.38E-29 T 22-04-2016 HRM2_RS08090 ed742527ad07bb01751e0ab25444c6d1 439 PANTHER PTHR30572 32 351 1.9E-70 T 22-04-2016 HRM2_RS08090 ed742527ad07bb01751e0ab25444c6d1 439 PANTHER PTHR30572:SF1 32 351 1.9E-70 T 22-04-2016 HRM2_RS08090 ed742527ad07bb01751e0ab25444c6d1 439 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 69 347 3.0E-36 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 HRM2_RS08090 ed742527ad07bb01751e0ab25444c6d1 439 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 73 326 5.8E-21 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain HRM2_RS08090 ed742527ad07bb01751e0ab25444c6d1 439 SUPERFAMILY SSF111369 75 330 1.7E-16 T 22-04-2016 HRM2_RS08090 ed742527ad07bb01751e0ab25444c6d1 439 Gene3D G3DSA:2.40.50.100 88 122 3.0E-14 T 22-04-2016 HRM2_RS08090 ed742527ad07bb01751e0ab25444c6d1 439 Gene3D G3DSA:2.40.50.100 214 245 3.0E-14 T 22-04-2016 HRM2_RS23895 ab9f09e7695d12fc169ead13558ce209 490 PANTHER PTHR35004 77 425 6.6E-66 T 22-04-2016 HRM2_RS23895 ab9f09e7695d12fc169ead13558ce209 490 Gene3D G3DSA:3.30.420.10 114 278 8.2E-8 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS23895 ab9f09e7695d12fc169ead13558ce209 490 SUPERFAMILY SSF53098 113 280 4.8E-10 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS23895 ab9f09e7695d12fc169ead13558ce209 490 PANTHER PTHR35004:SF2 77 425 6.6E-66 T 22-04-2016 HRM2_RS23895 ab9f09e7695d12fc169ead13558ce209 490 Pfam PF00665 Integrase core domain 114 240 2.9E-16 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 HRM2_RS21880 ab9f09e7695d12fc169ead13558ce209 490 PANTHER PTHR35004 77 425 6.6E-66 T 22-04-2016 HRM2_RS21880 ab9f09e7695d12fc169ead13558ce209 490 Gene3D G3DSA:3.30.420.10 114 278 8.2E-8 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS21880 ab9f09e7695d12fc169ead13558ce209 490 SUPERFAMILY SSF53098 113 280 4.8E-10 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS21880 ab9f09e7695d12fc169ead13558ce209 490 PANTHER PTHR35004:SF2 77 425 6.6E-66 T 22-04-2016 HRM2_RS21880 ab9f09e7695d12fc169ead13558ce209 490 Pfam PF00665 Integrase core domain 114 240 2.9E-16 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 HRM2_RS06785 97c6176b4b845b7d1cf1f59eeb08e14d 371 Pfam PF13237 4Fe-4S dicluster domain 13 62 1.9E-6 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS06785 97c6176b4b845b7d1cf1f59eeb08e14d 371 PANTHER PTHR31332 3 322 8.1E-48 T 22-04-2016 HRM2_RS06785 97c6176b4b845b7d1cf1f59eeb08e14d 371 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 51 62 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS06785 97c6176b4b845b7d1cf1f59eeb08e14d 371 Gene3D G3DSA:3.30.70.20 13 69 8.7E-11 T 22-04-2016 HRM2_RS06785 97c6176b4b845b7d1cf1f59eeb08e14d 371 SUPERFAMILY SSF54862 14 66 1.9E-12 T 22-04-2016 HRM2_RS06785 97c6176b4b845b7d1cf1f59eeb08e14d 371 Pfam PF04422 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term 89 159 3.6E-15 T 22-04-2016 IPR007516 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal HRM2_RS06785 97c6176b4b845b7d1cf1f59eeb08e14d 371 Pfam PF04432 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus 184 323 2.1E-33 T 22-04-2016 IPR007525 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal HRM2_RS06785 97c6176b4b845b7d1cf1f59eeb08e14d 371 PANTHER PTHR31332:SF1 3 322 8.1E-48 T 22-04-2016 HRM2_RS23100 c28f1881d09f15ac597ae613638bab24 291 PANTHER PTHR11795 1 290 4.4E-90 T 22-04-2016 HRM2_RS23100 c28f1881d09f15ac597ae613638bab24 291 PANTHER PTHR11795:SF398 1 290 4.4E-90 T 22-04-2016 HRM2_RS23100 c28f1881d09f15ac597ae613638bab24 291 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 275 1.1E-35 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 HRM2_RS21140 c41c381fd83661d13300008f184722cc 279 PRINTS PR00169 Potassium channel signature 89 109 1.1E-37 T 22-04-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 HRM2_RS21140 c41c381fd83661d13300008f184722cc 279 PRINTS PR00169 Potassium channel signature 154 177 1.1E-37 T 22-04-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 HRM2_RS21140 c41c381fd83661d13300008f184722cc 279 PRINTS PR00169 Potassium channel signature 212 238 1.1E-37 T 22-04-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 HRM2_RS21140 c41c381fd83661d13300008f184722cc 279 PRINTS PR00169 Potassium channel signature 21 49 1.1E-37 T 22-04-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 HRM2_RS21140 c41c381fd83661d13300008f184722cc 279 PRINTS PR00169 Potassium channel signature 63 86 1.1E-37 T 22-04-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 HRM2_RS21140 c41c381fd83661d13300008f184722cc 279 PRINTS PR00169 Potassium channel signature 125 151 1.1E-37 T 22-04-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 HRM2_RS21140 c41c381fd83661d13300008f184722cc 279 PRINTS PR00169 Potassium channel signature 183 205 1.1E-37 T 22-04-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 HRM2_RS21140 c41c381fd83661d13300008f184722cc 279 Pfam PF00520 Ion transport protein 28 244 2.0E-33 T 22-04-2016 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 HRM2_RS21140 c41c381fd83661d13300008f184722cc 279 SUPERFAMILY SSF81324 28 238 1.14E-52 T 22-04-2016 HRM2_RS21140 c41c381fd83661d13300008f184722cc 279 Gene3D G3DSA:1.10.287.70 29 238 2.2E-50 T 22-04-2016 HRM2_RS21140 c41c381fd83661d13300008f184722cc 279 PANTHER PTHR11537:SF137 9 277 4.5E-103 T 22-04-2016 HRM2_RS21140 c41c381fd83661d13300008f184722cc 279 PANTHER PTHR11537 9 277 4.5E-103 T 22-04-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 HRM2_RS18715 ef08784265ff10713f3f63f806b7cd12 359 Gene3D G3DSA:3.40.50.1110 86 164 4.9E-14 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain HRM2_RS18715 ef08784265ff10713f3f63f806b7cd12 359 Gene3D G3DSA:3.40.50.1110 228 349 4.9E-14 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain HRM2_RS18715 ef08784265ff10713f3f63f806b7cd12 359 SUPERFAMILY SSF52266 86 169 6.91E-15 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain HRM2_RS18715 ef08784265ff10713f3f63f806b7cd12 359 SUPERFAMILY SSF52266 230 350 6.91E-15 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain HRM2_RS07680 9d8fc765e1faa707b027e6a5030e8354 380 SUPERFAMILY SSF56796 7 377 1.22E-104 T 22-04-2016 HRM2_RS07680 9d8fc765e1faa707b027e6a5030e8354 380 Gene3D G3DSA:1.20.1090.10 186 379 2.1E-49 T 22-04-2016 HRM2_RS07680 9d8fc765e1faa707b027e6a5030e8354 380 PANTHER PTHR11496 9 375 1.2E-91 T 22-04-2016 HRM2_RS07680 9d8fc765e1faa707b027e6a5030e8354 380 Pfam PF00465 Iron-containing alcohol dehydrogenase 10 372 2.8E-102 T 22-04-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 HRM2_RS07680 9d8fc765e1faa707b027e6a5030e8354 380 Gene3D G3DSA:3.40.50.1970 8 181 1.4E-54 T 22-04-2016 HRM2_RS11590 b84d79464c7e8e9575142ea5bfe33442 286 Gene3D G3DSA:3.40.50.1000 184 275 1.6E-35 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS11590 b84d79464c7e8e9575142ea5bfe33442 286 Gene3D G3DSA:3.40.50.1000 1 77 1.6E-35 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS11590 b84d79464c7e8e9575142ea5bfe33442 286 PANTHER PTHR10000 1 280 1.3E-34 T 22-04-2016 HRM2_RS11590 b84d79464c7e8e9575142ea5bfe33442 286 Pfam PF08282 haloacid dehalogenase-like hydrolase 3 274 1.3E-36 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS11590 b84d79464c7e8e9575142ea5bfe33442 286 PANTHER PTHR10000:SF8 1 280 1.3E-34 T 22-04-2016 HRM2_RS11590 b84d79464c7e8e9575142ea5bfe33442 286 SUPERFAMILY SSF56784 1 275 5.89E-42 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS09770 87456fdd773f3489beba1954fd546b01 194 Pfam PF02563 Polysaccharide biosynthesis/export protein 33 107 2.8E-20 T 22-04-2016 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 HRM2_RS09770 87456fdd773f3489beba1954fd546b01 194 PANTHER PTHR33619 36 194 2.3E-37 T 22-04-2016 HRM2_RS09770 87456fdd773f3489beba1954fd546b01 194 Gene3D G3DSA:3.30.1950.10 41 101 1.0E-17 T 22-04-2016 HRM2_RS09770 87456fdd773f3489beba1954fd546b01 194 Gene3D G3DSA:3.10.560.10 102 193 1.1E-16 T 22-04-2016 HRM2_RS11710 ef173b963f3372dd72dcf8b8a3ccae19 244 PANTHER PTHR11085 3 241 9.1E-75 T 22-04-2016 IPR003000 Sirtuin family GO:0070403 HRM2_RS11710 ef173b963f3372dd72dcf8b8a3ccae19 244 Pfam PF02146 Sir2 family 20 192 5.3E-48 T 22-04-2016 IPR003000 Sirtuin family GO:0070403 HRM2_RS11710 ef173b963f3372dd72dcf8b8a3ccae19 244 Gene3D G3DSA:3.40.50.1220 80 117 4.8E-39 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HRM2_RS11710 ef173b963f3372dd72dcf8b8a3ccae19 244 Gene3D G3DSA:3.40.50.1220 168 242 4.8E-39 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HRM2_RS11710 ef173b963f3372dd72dcf8b8a3ccae19 244 Gene3D G3DSA:3.40.50.1220 3 30 4.8E-39 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HRM2_RS11710 ef173b963f3372dd72dcf8b8a3ccae19 244 SUPERFAMILY SSF52467 4 241 3.74E-71 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HRM2_RS11710 ef173b963f3372dd72dcf8b8a3ccae19 244 Gene3D G3DSA:3.30.1600.10 118 162 9.2E-23 T 22-04-2016 IPR026591 Sirtuin family, catalytic core small domain HRM2_RS11710 ef173b963f3372dd72dcf8b8a3ccae19 244 Gene3D G3DSA:3.30.1600.10 31 67 9.2E-23 T 22-04-2016 IPR026591 Sirtuin family, catalytic core small domain HRM2_RS23170 6f0a18291e6394569d6e97da47a214f1 126 SMART SM01078 3 115 5.2E-5 T 22-04-2016 IPR014925 Uncharacterised domain CGGC-dom HRM2_RS23170 6f0a18291e6394569d6e97da47a214f1 126 Pfam PF08821 CGGC domain 3 113 2.1E-23 T 22-04-2016 IPR014925 Uncharacterised domain CGGC-dom HRM2_RS24970 2a6a6732782451286e3f54cb824b81fe 218 Pfam PF04351 Pilus assembly protein, PilP 90 211 2.6E-19 T 22-04-2016 IPR007446 Pilus assembly protein PilP HRM2_RS10025 48ff4cc55623141bedf1a599774df4ca 420 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 298 383 5.4E-11 T 22-04-2016 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HRM2_RS10025 48ff4cc55623141bedf1a599774df4ca 420 PANTHER PTHR11926:SF335 202 354 1.7E-21 T 22-04-2016 HRM2_RS10025 48ff4cc55623141bedf1a599774df4ca 420 PANTHER PTHR11926:SF335 177 182 1.7E-21 T 22-04-2016 HRM2_RS10025 48ff4cc55623141bedf1a599774df4ca 420 PANTHER PTHR11926:SF335 67 160 1.7E-21 T 22-04-2016 HRM2_RS10025 48ff4cc55623141bedf1a599774df4ca 420 Gene3D G3DSA:3.40.50.2000 242 380 1.1E-18 T 22-04-2016 HRM2_RS10025 48ff4cc55623141bedf1a599774df4ca 420 SUPERFAMILY SSF53756 9 405 9.42E-43 T 22-04-2016 HRM2_RS10025 48ff4cc55623141bedf1a599774df4ca 420 PANTHER PTHR11926 202 354 1.7E-21 T 22-04-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 HRM2_RS10025 48ff4cc55623141bedf1a599774df4ca 420 PANTHER PTHR11926 177 182 1.7E-21 T 22-04-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 HRM2_RS10025 48ff4cc55623141bedf1a599774df4ca 420 PANTHER PTHR11926 67 160 1.7E-21 T 22-04-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 HRM2_RS12665 d8403100f9433eb090fe633a287e71f8 93 Pfam PF15781 ParE-like toxin of type II bacterial toxin-antitoxin system 7 91 1.6E-37 T 22-04-2016 IPR031552 Type II bacterial toxin-antitoxin system, ParE-like toxin HRM2_RS01775 33add42a0dc012a3928a3cfe8895ec19 324 SUPERFAMILY SSF52266 210 305 6.6E-7 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain HRM2_RS01775 33add42a0dc012a3928a3cfe8895ec19 324 Gene3D G3DSA:3.40.50.1110 214 299 5.6E-5 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain HRM2_RS00035 7b79c3e56ceca3632cacd5f713ebe839 478 Pfam PF01618 MotA/TolQ/ExbB proton channel family 340 460 3.7E-32 T 22-04-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 HRM2_RS00035 7b79c3e56ceca3632cacd5f713ebe839 478 PANTHER PTHR30625 117 468 2.3E-49 T 22-04-2016 HRM2_RS00035 7b79c3e56ceca3632cacd5f713ebe839 478 PANTHER PTHR30625:SF0 117 468 2.3E-49 T 22-04-2016 HRM2_RS00035 7b79c3e56ceca3632cacd5f713ebe839 478 PIRSF PIRSF037714 2 471 1.4E-95 T 22-04-2016 IPR017270 Putative MotA/TolQ/ExbB family protein HRM2_RS20200 e9fb1da6d76abf616ec133ef44132c6c 185 SUPERFAMILY SSF52833 53 152 4.35E-12 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS20200 e9fb1da6d76abf616ec133ef44132c6c 185 ProSitePatterns PS00194 Thioredoxin family active site. 64 82 - T 22-04-2016 IPR017937 Thioredoxin, conserved site GO:0045454 HRM2_RS20200 e9fb1da6d76abf616ec133ef44132c6c 185 Gene3D G3DSA:3.40.30.10 3 165 8.0E-14 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS20200 e9fb1da6d76abf616ec133ef44132c6c 185 Pfam PF00578 AhpC/TSA family 53 144 2.4E-6 T 22-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 HRM2_RS09330 21bf1713a1528023f2b16fd64a1bb993 630 Pfam PF13624 SurA N-terminal domain 1 161 3.0E-49 T 22-04-2016 HRM2_RS09330 21bf1713a1528023f2b16fd64a1bb993 630 PANTHER PTHR10657 1 172 2.9E-73 T 22-04-2016 HRM2_RS09330 21bf1713a1528023f2b16fd64a1bb993 630 PANTHER PTHR10657 238 512 2.9E-73 T 22-04-2016 HRM2_RS09330 21bf1713a1528023f2b16fd64a1bb993 630 PANTHER PTHR10657:SF11 1 172 2.9E-73 T 22-04-2016 HRM2_RS09330 21bf1713a1528023f2b16fd64a1bb993 630 PANTHER PTHR10657:SF11 238 512 2.9E-73 T 22-04-2016 HRM2_RS09330 21bf1713a1528023f2b16fd64a1bb993 630 Gene3D G3DSA:3.10.50.40 441 496 7.0E-6 T 22-04-2016 HRM2_RS09330 21bf1713a1528023f2b16fd64a1bb993 630 Gene3D G3DSA:3.10.50.40 257 385 2.1E-42 T 22-04-2016 HRM2_RS09330 21bf1713a1528023f2b16fd64a1bb993 630 Pfam PF13616 PPIC-type PPIASE domain 257 365 8.9E-26 T 22-04-2016 HRM2_RS09330 21bf1713a1528023f2b16fd64a1bb993 630 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 304 324 - T 22-04-2016 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site HRM2_RS09330 21bf1713a1528023f2b16fd64a1bb993 630 SUPERFAMILY SSF109998 238 293 1.57E-33 T 22-04-2016 IPR027304 Trigger factor/SurA domain HRM2_RS09330 21bf1713a1528023f2b16fd64a1bb993 630 SUPERFAMILY SSF109998 39 165 1.57E-33 T 22-04-2016 IPR027304 Trigger factor/SurA domain HRM2_RS09330 21bf1713a1528023f2b16fd64a1bb993 630 SUPERFAMILY SSF54534 257 363 3.14E-31 T 22-04-2016 HRM2_RS07355 eb31261d884b94154de2462705c244fc 222 SMART SM00327 11 188 1.2E-14 T 22-04-2016 IPR002035 von Willebrand factor, type A HRM2_RS07355 eb31261d884b94154de2462705c244fc 222 SUPERFAMILY SSF53300 10 187 4.45E-24 T 22-04-2016 IPR002035 von Willebrand factor, type A HRM2_RS07355 eb31261d884b94154de2462705c244fc 222 Pfam PF00092 von Willebrand factor type A domain 14 177 3.2E-13 T 22-04-2016 IPR002035 von Willebrand factor, type A HRM2_RS07355 eb31261d884b94154de2462705c244fc 222 Gene3D G3DSA:3.40.50.410 10 189 5.5E-19 T 22-04-2016 IPR002035 von Willebrand factor, type A HRM2_RS02855 5ed35703a82bbb64a159d1c72c03fe8b 149 SUPERFAMILY SSF48371 23 128 1.04E-5 T 22-04-2016 IPR016024 Armadillo-type fold GO:0005488 HRM2_RS02855 5ed35703a82bbb64a159d1c72c03fe8b 149 Gene3D G3DSA:1.25.10.10 33 93 2.0E-4 T 22-04-2016 IPR011989 Armadillo-like helical HRM2_RS20735 cdb4b1c94e1688d3ae59f297392dd29b 150 Pfam PF07879 PHB/PHA accumulation regulator DNA-binding domain 7 64 2.2E-27 T 22-04-2016 IPR012909 PHA accumulation regulator DNA-binding, N-terminal HRM2_RS09760 addae9624244264dbe79bd22a2dca326 285 PANTHER PTHR32309 76 285 1.7E-47 T 22-04-2016 HRM2_RS09760 addae9624244264dbe79bd22a2dca326 285 Gene3D G3DSA:3.40.50.300 101 278 8.5E-35 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09760 addae9624244264dbe79bd22a2dca326 285 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 82 277 3.3E-40 T 22-04-2016 IPR005702 Exopolysaccharide synthesis protein GO:0045226 HRM2_RS09760 addae9624244264dbe79bd22a2dca326 285 SUPERFAMILY SSF52540 100 279 3.85E-35 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09760 addae9624244264dbe79bd22a2dca326 285 PANTHER PTHR32309:SF13 76 285 1.7E-47 T 22-04-2016 HRM2_RS09760 addae9624244264dbe79bd22a2dca326 285 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 103 277 3.7E-13 T 22-04-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain HRM2_RS21825 f761c16503bde4ba24b9507857ed6154 177 Pfam PF00583 Acetyltransferase (GNAT) family 95 153 2.3E-7 T 22-04-2016 IPR000182 GNAT domain GO:0008080 HRM2_RS21825 f761c16503bde4ba24b9507857ed6154 177 Gene3D G3DSA:3.40.630.30 93 154 2.8E-12 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS21825 f761c16503bde4ba24b9507857ed6154 177 PANTHER PTHR36449 1 177 1.3E-49 T 22-04-2016 HRM2_RS21825 f761c16503bde4ba24b9507857ed6154 177 SUPERFAMILY SSF55729 88 155 1.8E-12 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS16160 4338820693be1e9d5c6537286c09151b 131 PANTHER PTHR35335 1 127 1.8E-33 T 22-04-2016 HRM2_RS16160 4338820693be1e9d5c6537286c09151b 131 Pfam PF04186 FxsA cytoplasmic membrane protein 8 114 7.6E-36 T 22-04-2016 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 HRM2_RS16160 4338820693be1e9d5c6537286c09151b 131 PANTHER PTHR35335:SF1 1 127 1.8E-33 T 22-04-2016 HRM2_RS17630 ca3818ef469687de83be1cccc79dd95d 430 Gene3D G3DSA:3.20.20.70 341 378 9.5E-43 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS17630 ca3818ef469687de83be1cccc79dd95d 430 Gene3D G3DSA:3.20.20.70 46 293 9.5E-43 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS17630 ca3818ef469687de83be1cccc79dd95d 430 Pfam PF01116 Fructose-bisphosphate aldolase class-II 46 288 8.5E-25 T 22-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 HRM2_RS17630 ca3818ef469687de83be1cccc79dd95d 430 SUPERFAMILY SSF51569 35 366 4.21E-35 T 22-04-2016 HRM2_RS01565 c30bd245ef6ffb69e6a76b33e04dbd95 290 PANTHER PTHR32479:SF12 1 289 3.9E-27 T 22-04-2016 HRM2_RS01565 c30bd245ef6ffb69e6a76b33e04dbd95 290 PANTHER PTHR32479 1 289 3.9E-27 T 22-04-2016 HRM2_RS01565 c30bd245ef6ffb69e6a76b33e04dbd95 290 Pfam PF02754 Cysteine-rich domain 3 83 1.0E-10 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS01565 c30bd245ef6ffb69e6a76b33e04dbd95 290 Pfam PF02754 Cysteine-rich domain 154 241 1.2E-12 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS18540 2a64f9409f5aeb2c2799f4c3e3013cc4 382 Gene3D G3DSA:3.40.50.920 270 375 5.8E-22 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HRM2_RS18540 2a64f9409f5aeb2c2799f4c3e3013cc4 382 SUPERFAMILY SSF52922 269 377 1.43E-23 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HRM2_RS18540 2a64f9409f5aeb2c2799f4c3e3013cc4 382 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 276 370 6.5E-22 T 22-04-2016 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II HRM2_RS18540 2a64f9409f5aeb2c2799f4c3e3013cc4 382 PANTHER PTHR32154:SF14 7 186 2.9E-114 T 22-04-2016 HRM2_RS18540 2a64f9409f5aeb2c2799f4c3e3013cc4 382 PANTHER PTHR32154:SF14 215 379 2.9E-114 T 22-04-2016 HRM2_RS18540 2a64f9409f5aeb2c2799f4c3e3013cc4 382 SUPERFAMILY SSF52518 4 259 8.34E-69 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS18540 2a64f9409f5aeb2c2799f4c3e3013cc4 382 Gene3D G3DSA:3.40.50.970 3 190 2.2E-79 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS18540 2a64f9409f5aeb2c2799f4c3e3013cc4 382 PANTHER PTHR32154 7 186 2.9E-114 T 22-04-2016 HRM2_RS18540 2a64f9409f5aeb2c2799f4c3e3013cc4 382 PANTHER PTHR32154 215 379 2.9E-114 T 22-04-2016 HRM2_RS18540 2a64f9409f5aeb2c2799f4c3e3013cc4 382 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 16 198 1.7E-65 T 22-04-2016 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 HRM2_RS18615 9bb7448ac014008608f3f19c4ce7d421 411 PANTHER PTHR23521:SF2 2 393 8.9E-103 T 22-04-2016 HRM2_RS18615 9bb7448ac014008608f3f19c4ce7d421 411 PANTHER PTHR23521 2 393 8.9E-103 T 22-04-2016 HRM2_RS18615 9bb7448ac014008608f3f19c4ce7d421 411 Gene3D G3DSA:1.20.1250.20 8 179 3.2E-14 T 22-04-2016 HRM2_RS18615 9bb7448ac014008608f3f19c4ce7d421 411 SUPERFAMILY SSF103473 8 376 2.22E-41 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS18615 9bb7448ac014008608f3f19c4ce7d421 411 Gene3D G3DSA:1.20.1250.20 201 377 5.4E-20 T 22-04-2016 HRM2_RS18615 9bb7448ac014008608f3f19c4ce7d421 411 Pfam PF07690 Major Facilitator Superfamily 13 245 1.7E-16 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS16525 20a48002937f06242a2bfcd8fc77fc93 280 SUPERFAMILY SSF52833 127 244 6.87E-10 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS16525 20a48002937f06242a2bfcd8fc77fc93 280 Gene3D G3DSA:3.40.30.10 135 246 7.2E-10 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS06420 01650dc40fa536d49fb8fcebc782e688 514 PANTHER PTHR30290 31 510 1.3E-91 T 22-04-2016 HRM2_RS06420 01650dc40fa536d49fb8fcebc782e688 514 Gene3D G3DSA:3.10.105.10 306 484 1.0E-37 T 22-04-2016 HRM2_RS06420 01650dc40fa536d49fb8fcebc782e688 514 SUPERFAMILY SSF53850 29 513 6.33E-109 T 22-04-2016 HRM2_RS06420 01650dc40fa536d49fb8fcebc782e688 514 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 77 429 2.9E-74 T 22-04-2016 IPR000914 Solute-binding protein family 5 domain HRM2_RS06420 01650dc40fa536d49fb8fcebc782e688 514 PIRSF PIRSF002741 2 514 7.6E-84 T 22-04-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 HRM2_RS06420 01650dc40fa536d49fb8fcebc782e688 514 Gene3D G3DSA:3.40.190.10 187 305 5.9E-34 T 22-04-2016 HRM2_RS06420 01650dc40fa536d49fb8fcebc782e688 514 Gene3D G3DSA:3.90.76.10 44 186 3.6E-32 T 22-04-2016 HRM2_RS17490 053e8b1d7ea49b3c3ee3705887af5fce 94 PANTHER PTHR34702:SF1 1 94 4.8E-14 T 22-04-2016 HRM2_RS17490 053e8b1d7ea49b3c3ee3705887af5fce 94 PANTHER PTHR34702 1 94 4.8E-14 T 22-04-2016 HRM2_RS17490 053e8b1d7ea49b3c3ee3705887af5fce 94 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 30 82 1.1E-14 T 22-04-2016 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 HRM2_RS17785 6284900399213a3ef0fc014d9e9b4f49 208 Gene3D G3DSA:1.10.1050.10 1 100 1.5E-42 T 22-04-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 HRM2_RS17785 6284900399213a3ef0fc014d9e9b4f49 208 SMART SM01390 3 97 1.9E-54 T 22-04-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 HRM2_RS17785 6284900399213a3ef0fc014d9e9b4f49 208 Gene3D G3DSA:3.10.290.10 101 200 3.4E-29 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HRM2_RS17785 6284900399213a3ef0fc014d9e9b4f49 208 PANTHER PTHR11831 1 208 2.1E-84 T 22-04-2016 IPR022801 Ribosomal protein S4/S9 HRM2_RS17785 6284900399213a3ef0fc014d9e9b4f49 208 SMART SM00363 98 162 1.4E-15 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HRM2_RS17785 6284900399213a3ef0fc014d9e9b4f49 208 PANTHER PTHR11831:SF4 1 208 2.1E-84 T 22-04-2016 HRM2_RS17785 6284900399213a3ef0fc014d9e9b4f49 208 SUPERFAMILY SSF55174 3 208 1.01E-69 T 22-04-2016 HRM2_RS17785 6284900399213a3ef0fc014d9e9b4f49 208 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 208 35.142 T 22-04-2016 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 HRM2_RS17785 6284900399213a3ef0fc014d9e9b4f49 208 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 97 3.0E-27 T 22-04-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 HRM2_RS17785 6284900399213a3ef0fc014d9e9b4f49 208 Pfam PF01479 S4 domain 98 145 1.6E-17 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HRM2_RS17785 6284900399213a3ef0fc014d9e9b4f49 208 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 208 1.7E-74 T 22-04-2016 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 HRM2_RS20555 0595fc112e2735e0fc725626b5d2ee7e 203 SUPERFAMILY SSF53254 4 187 2.36E-49 T 22-04-2016 IPR029033 Histidine phosphatase superfamily HRM2_RS20555 0595fc112e2735e0fc725626b5d2ee7e 203 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 185 8.6E-49 T 22-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 HRM2_RS20555 0595fc112e2735e0fc725626b5d2ee7e 203 SMART SM00855 3 157 6.3E-21 T 22-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 HRM2_RS20555 0595fc112e2735e0fc725626b5d2ee7e 203 PANTHER PTHR23029 6 163 3.3E-45 T 22-04-2016 HRM2_RS20555 0595fc112e2735e0fc725626b5d2ee7e 203 PANTHER PTHR23029:SF1 6 163 3.3E-45 T 22-04-2016 HRM2_RS20555 0595fc112e2735e0fc725626b5d2ee7e 203 Gene3D G3DSA:3.40.50.1240 4 196 3.7E-49 T 22-04-2016 IPR029033 Histidine phosphatase superfamily HRM2_RS16420 e65154114a9248572cff979755cdb56d 219 PANTHER PTHR34322:SF1 2 219 4.6E-64 T 22-04-2016 HRM2_RS16420 e65154114a9248572cff979755cdb56d 219 PANTHER PTHR34322 2 219 4.6E-64 T 22-04-2016 HRM2_RS16420 e65154114a9248572cff979755cdb56d 219 Pfam PF01797 Transposase IS200 like 12 121 1.1E-20 T 22-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 HRM2_RS16420 e65154114a9248572cff979755cdb56d 219 SUPERFAMILY SSF143422 3 126 1.83E-32 T 22-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 HRM2_RS16420 e65154114a9248572cff979755cdb56d 219 Gene3D G3DSA:3.30.70.1290 8 126 6.2E-19 T 22-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 HRM2_RS16420 e65154114a9248572cff979755cdb56d 219 SMART SM01321 9 123 2.7E-39 T 22-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 HRM2_RS23580 c1584211b8673f17da8fee948b210b02 224 Gene3D G3DSA:3.40.50.720 10 195 6.7E-8 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS23580 c1584211b8673f17da8fee948b210b02 224 SUPERFAMILY SSF51735 5 200 1.1E-11 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS22815 25e95b62d2186c17e52d125869bd182e 120 Pfam PF03551 Transcriptional regulator PadR-like family 22 95 1.2E-16 T 22-04-2016 IPR005149 Transcription regulator PadR, N-terminal HRM2_RS22815 25e95b62d2186c17e52d125869bd182e 120 PANTHER PTHR33169 22 115 4.3E-17 T 22-04-2016 HRM2_RS22815 25e95b62d2186c17e52d125869bd182e 120 SUPERFAMILY SSF46785 15 105 2.46E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS22815 25e95b62d2186c17e52d125869bd182e 120 Gene3D G3DSA:1.10.10.10 16 114 7.9E-24 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS18835 3658137a22080691289ffb2606414706 144 SUPERFAMILY SSF52172 6 128 3.13E-33 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS18835 3658137a22080691289ffb2606414706 144 Pfam PF00072 Response regulator receiver domain 9 117 1.7E-26 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18835 3658137a22080691289ffb2606414706 144 SMART SM00448 6 117 1.5E-27 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18835 3658137a22080691289ffb2606414706 144 Gene3D G3DSA:3.40.50.2300 6 131 2.0E-34 T 22-04-2016 HRM2_RS18835 3658137a22080691289ffb2606414706 144 PANTHER PTHR26402 6 140 1.7E-31 T 22-04-2016 HRM2_RS12840 08f4bd12c17ebb362d9c30b6976962f9 100 Pfam PF02085 Class III cytochrome C family 10 96 4.0E-10 T 22-04-2016 IPR020942 Class III cytochrome C GO:0009055|GO:0020037 HRM2_RS12840 08f4bd12c17ebb362d9c30b6976962f9 100 Gene3D G3DSA:3.90.10.10 56 97 1.8E-9 T 22-04-2016 HRM2_RS12840 08f4bd12c17ebb362d9c30b6976962f9 100 Gene3D G3DSA:3.90.10.10 7 55 1.5E-5 T 22-04-2016 HRM2_RS12840 08f4bd12c17ebb362d9c30b6976962f9 100 SUPERFAMILY SSF48695 8 97 1.23E-17 T 22-04-2016 IPR011031 Multihaem cytochrome HRM2_RS14110 8a295a2b8d0d1dafc496592ef7635d8d 272 Pfam PF12654 Domain of unknown function (DUF3786) 82 255 6.1E-42 T 22-04-2016 IPR024264 Domain of unknown function DUF3786 HRM2_RS14110 8a295a2b8d0d1dafc496592ef7635d8d 272 Pfam PF04060 Putative Fe-S cluster 12 44 9.8E-11 T 22-04-2016 IPR007202 4Fe-4S domain GO:0051536 HRM2_RS03525 bd7f0063b750ad48be692e5c75aa70e1 93 PANTHER PTHR40266 1 93 9.1E-41 T 22-04-2016 HRM2_RS03525 bd7f0063b750ad48be692e5c75aa70e1 93 SUPERFAMILY SSF143011 1 93 1.44E-16 T 22-04-2016 HRM2_RS03525 bd7f0063b750ad48be692e5c75aa70e1 93 Pfam PF05015 RelE-like toxin of type II toxin-antitoxin system HigB 5 93 6.9E-18 T 22-04-2016 IPR007711 Toxin HigB-1 HRM2_RS03525 bd7f0063b750ad48be692e5c75aa70e1 93 PANTHER PTHR40266:SF2 1 93 9.1E-41 T 22-04-2016 HRM2_RS19940 1dfd5c80f4c2f4addfa269431e98892e 188 Pfam PF02659 Putative manganese efflux pump 33 182 5.0E-51 T 22-04-2016 IPR003810 Putative manganese efflux pump HRM2_RS19940 1dfd5c80f4c2f4addfa269431e98892e 188 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 1 185 25.905 T 22-04-2016 IPR022929 Putative manganese efflux pump MntP HRM2_RS19940 1dfd5c80f4c2f4addfa269431e98892e 188 PANTHER PTHR35529 2 188 1.9E-55 T 22-04-2016 HRM2_RS21590 a3e278984bdc543ce6b3481afbb08881 71 SUPERFAMILY SSF143120 1 66 5.1E-20 T 22-04-2016 HRM2_RS21590 a3e278984bdc543ce6b3481afbb08881 71 PANTHER PTHR33713:SF6 1 66 5.9E-21 T 22-04-2016 HRM2_RS21590 a3e278984bdc543ce6b3481afbb08881 71 PANTHER PTHR33713 1 66 5.9E-21 T 22-04-2016 HRM2_RS21590 a3e278984bdc543ce6b3481afbb08881 71 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 3 56 1.1E-14 T 22-04-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM HRM2_RS21590 a3e278984bdc543ce6b3481afbb08881 71 Gene3D G3DSA:3.40.1620.10 2 51 5.3E-10 T 22-04-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM HRM2_RS21590 a3e278984bdc543ce6b3481afbb08881 71 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 66 2.5E-20 T 22-04-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM HRM2_RS03975 c58a37a7872d8513c46f4ab50fd5fc10 474 SUPERFAMILY SSF103473 246 460 6.02E-64 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS03975 c58a37a7872d8513c46f4ab50fd5fc10 474 SUPERFAMILY SSF103473 13 192 6.02E-64 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS03975 c58a37a7872d8513c46f4ab50fd5fc10 474 Gene3D G3DSA:1.20.1250.20 262 457 5.3E-21 T 22-04-2016 HRM2_RS03975 c58a37a7872d8513c46f4ab50fd5fc10 474 Pfam PF07690 Major Facilitator Superfamily 20 407 1.1E-51 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS03975 c58a37a7872d8513c46f4ab50fd5fc10 474 Gene3D G3DSA:1.20.1250.20 15 189 5.9E-29 T 22-04-2016 HRM2_RS03975 c58a37a7872d8513c46f4ab50fd5fc10 474 PANTHER PTHR23501:SF5 13 467 7.3E-107 T 22-04-2016 HRM2_RS03975 c58a37a7872d8513c46f4ab50fd5fc10 474 PANTHER PTHR23501 13 467 7.3E-107 T 22-04-2016 HRM2_RS12130 7a7797dbc4dedbc869b404771f03f190 510 SUPERFAMILY SSF52743 211 503 7.99E-42 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HRM2_RS12130 7a7797dbc4dedbc869b404771f03f190 510 PANTHER PTHR10795:SF419 183 498 1.1E-23 T 22-04-2016 HRM2_RS12130 7a7797dbc4dedbc869b404771f03f190 510 Pfam PF00082 Subtilase family 313 497 1.0E-18 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HRM2_RS12130 7a7797dbc4dedbc869b404771f03f190 510 PANTHER PTHR10795 183 498 1.1E-23 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related HRM2_RS12130 7a7797dbc4dedbc869b404771f03f190 510 Gene3D G3DSA:3.40.50.200 230 500 6.6E-42 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HRM2_RS17010 9a28c34a63a423b0442863b136920422 141 Pfam PF00072 Response regulator receiver domain 5 118 6.4E-29 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS17010 9a28c34a63a423b0442863b136920422 141 SUPERFAMILY SSF52172 3 125 6.12E-35 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS17010 9a28c34a63a423b0442863b136920422 141 PANTHER PTHR26402 3 119 8.6E-39 T 22-04-2016 HRM2_RS17010 9a28c34a63a423b0442863b136920422 141 Gene3D G3DSA:3.40.50.2300 2 126 2.0E-36 T 22-04-2016 HRM2_RS17010 9a28c34a63a423b0442863b136920422 141 SMART SM00448 3 119 9.1E-34 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS13950 2e1b9d21acd103083c52345c0d405e7b 225 SUPERFAMILY SSF109998 36 189 1.37E-15 T 22-04-2016 IPR027304 Trigger factor/SurA domain HRM2_RS22830 c36ee318aa6bdc03545bb1d633622b82 165 Gene3D G3DSA:1.10.1510.10 17 97 9.5E-9 T 22-04-2016 HRM2_RS22830 c36ee318aa6bdc03545bb1d633622b82 165 Pfam PF09424 Yqey-like protein 20 153 5.0E-10 T 22-04-2016 IPR019004 Uncharacterised domain YOR215C, mitochondrial HRM2_RS22830 c36ee318aa6bdc03545bb1d633622b82 165 SUPERFAMILY SSF89095 17 161 3.82E-16 T 22-04-2016 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 HRM2_RS05405 af3a69b6b9b833a4d477980b58da87cf 226 Gene3D G3DSA:1.25.40.10 20 160 5.5E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS05405 af3a69b6b9b833a4d477980b58da87cf 226 Pfam PF09976 Tetratricopeptide repeat-like domain 38 164 2.7E-6 T 22-04-2016 IPR018704 Tetratricopeptide repeat-like domain HRM2_RS05405 af3a69b6b9b833a4d477980b58da87cf 226 Pfam PF13174 Tetratricopeptide repeat 181 213 1.9E-4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS05405 af3a69b6b9b833a4d477980b58da87cf 226 Gene3D G3DSA:1.25.40.10 161 217 3.8E-6 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS05405 af3a69b6b9b833a4d477980b58da87cf 226 SUPERFAMILY SSF48452 105 224 4.67E-13 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS02465 04acb686124d666bb450747056d5889c 166 PANTHER PTHR35794 1 159 5.3E-27 T 22-04-2016 HRM2_RS02465 04acb686124d666bb450747056d5889c 166 PANTHER PTHR35794:SF2 1 159 5.3E-27 T 22-04-2016 HRM2_RS02465 04acb686124d666bb450747056d5889c 166 Pfam PF05103 DivIVA protein 3 131 2.4E-31 T 22-04-2016 IPR007793 DivIVA family HRM2_RS02465 04acb686124d666bb450747056d5889c 166 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 35 1.2E-10 T 22-04-2016 IPR019933 DivIVA domain HRM2_RS00250 920b032449f2f6cc2f2127e3c2f1f2ae 301 PANTHER PTHR30349 1 290 6.8E-54 T 22-04-2016 HRM2_RS00250 920b032449f2f6cc2f2127e3c2f1f2ae 301 Gene3D G3DSA:1.10.443.10 111 293 1.7E-40 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS00250 920b032449f2f6cc2f2127e3c2f1f2ae 301 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 12 87 2.5E-10 T 22-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 HRM2_RS00250 920b032449f2f6cc2f2127e3c2f1f2ae 301 Gene3D G3DSA:1.10.150.130 18 98 1.6E-13 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal HRM2_RS00250 920b032449f2f6cc2f2127e3c2f1f2ae 301 SUPERFAMILY SSF56349 17 289 5.0E-48 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HRM2_RS00250 920b032449f2f6cc2f2127e3c2f1f2ae 301 Pfam PF00589 Phage integrase family 111 287 7.5E-29 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS00250 920b032449f2f6cc2f2127e3c2f1f2ae 301 PANTHER PTHR30349:SF5 1 290 6.8E-54 T 22-04-2016 HRM2_RS24135 81d0f3fec0d7f45f4b61182b48c3508f 527 SUPERFAMILY SSF51338 3 60 8.91E-19 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS24135 81d0f3fec0d7f45f4b61182b48c3508f 527 SUPERFAMILY SSF51338 483 523 8.91E-19 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS24135 81d0f3fec0d7f45f4b61182b48c3508f 527 PANTHER PTHR22642 3 524 4.3E-171 T 22-04-2016 HRM2_RS24135 81d0f3fec0d7f45f4b61182b48c3508f 527 PANTHER PTHR22642:SF2 3 524 4.3E-171 T 22-04-2016 HRM2_RS24135 81d0f3fec0d7f45f4b61182b48c3508f 527 Pfam PF07969 Amidohydrolase family 50 524 2.8E-95 T 22-04-2016 IPR013108 Amidohydrolase 3 HRM2_RS24135 81d0f3fec0d7f45f4b61182b48c3508f 527 Gene3D G3DSA:2.30.40.10 5 98 5.8E-17 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS24135 81d0f3fec0d7f45f4b61182b48c3508f 527 Gene3D G3DSA:2.30.40.10 423 523 1.4E-13 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HRM2_RS24135 81d0f3fec0d7f45f4b61182b48c3508f 527 Gene3D G3DSA:3.20.20.140 198 422 2.0E-20 T 22-04-2016 HRM2_RS24135 81d0f3fec0d7f45f4b61182b48c3508f 527 SUPERFAMILY SSF51556 196 484 6.03E-29 T 22-04-2016 IPR032466 Metal-dependent hydrolase HRM2_RS24135 81d0f3fec0d7f45f4b61182b48c3508f 527 SUPERFAMILY SSF51556 59 116 6.03E-29 T 22-04-2016 IPR032466 Metal-dependent hydrolase HRM2_RS14465 33cb15f1c9b4e9abd2e8c8789b077094 312 PANTHER PTHR30024:SF16 6 230 8.4E-25 T 22-04-2016 HRM2_RS14465 33cb15f1c9b4e9abd2e8c8789b077094 312 SUPERFAMILY SSF53850 4 237 4.35E-27 T 22-04-2016 HRM2_RS14465 33cb15f1c9b4e9abd2e8c8789b077094 312 Gene3D G3DSA:3.40.190.10 90 222 2.5E-10 T 22-04-2016 HRM2_RS14465 33cb15f1c9b4e9abd2e8c8789b077094 312 Pfam PF13379 NMT1-like family 4 239 8.4E-30 T 22-04-2016 HRM2_RS14465 33cb15f1c9b4e9abd2e8c8789b077094 312 PANTHER PTHR30024 6 230 8.4E-25 T 22-04-2016 HRM2_RS16240 f0a85f622195edbefdc229a23dae3752 385 SUPERFAMILY SSF103473 1 377 2.22E-36 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS16240 f0a85f622195edbefdc229a23dae3752 385 Pfam PF07690 Major Facilitator Superfamily 211 373 8.9E-11 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS16240 f0a85f622195edbefdc229a23dae3752 385 Gene3D G3DSA:1.20.1250.20 10 194 1.2E-12 T 22-04-2016 HRM2_RS16240 f0a85f622195edbefdc229a23dae3752 385 Gene3D G3DSA:1.20.1250.20 203 374 4.4E-21 T 22-04-2016 HRM2_RS03725 deeffd0c2871d99095e4154213fb891e 342 Pfam PF00274 Fructose-bisphosphate aldolase class-I 8 337 7.9E-145 T 22-04-2016 IPR000741 Fructose-bisphosphate aldolase, class-I GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HRM2_RS03725 deeffd0c2871d99095e4154213fb891e 342 SUPERFAMILY SSF51569 4 339 4.61E-134 T 22-04-2016 HRM2_RS03725 deeffd0c2871d99095e4154213fb891e 342 PANTHER PTHR11627 6 335 9.3E-183 T 22-04-2016 HRM2_RS03725 deeffd0c2871d99095e4154213fb891e 342 ProSitePatterns PS00158 Fructose-bisphosphate aldolase class-I active site. 214 224 - T 22-04-2016 IPR029768 Fructose-bisphosphate aldolase class-I active site KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385|UniPathway: UPA00109 HRM2_RS03725 deeffd0c2871d99095e4154213fb891e 342 Gene3D G3DSA:3.20.20.70 5 335 2.9E-151 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS13830 59e978826131362ed6d40c9f5d7e0dcb 99 PANTHER PTHR34182 2 96 8.4E-25 T 22-04-2016 HRM2_RS13830 59e978826131362ed6d40c9f5d7e0dcb 99 Pfam PF03840 Preprotein translocase SecG subunit 5 73 3.7E-22 T 22-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 HRM2_RS13830 59e978826131362ed6d40c9f5d7e0dcb 99 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 3.4E-28 T 22-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 HRM2_RS13830 59e978826131362ed6d40c9f5d7e0dcb 99 PRINTS PR01651 Protein-export SecG membrane protein signature 54 76 3.4E-28 T 22-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 HRM2_RS13830 59e978826131362ed6d40c9f5d7e0dcb 99 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 3.4E-28 T 22-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 HRM2_RS13830 59e978826131362ed6d40c9f5d7e0dcb 99 PRINTS PR01651 Protein-export SecG membrane protein signature 38 54 3.4E-28 T 22-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 HRM2_RS13830 59e978826131362ed6d40c9f5d7e0dcb 99 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 74 4.5E-24 T 22-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 HRM2_RS14920 e39aa11168dd86af5ca69651a9e5b64a 357 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 17 351 1.0E-24 T 22-04-2016 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD HRM2_RS14920 e39aa11168dd86af5ca69651a9e5b64a 357 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 10 336 9.6E-50 T 22-04-2016 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD HRM2_RS14920 e39aa11168dd86af5ca69651a9e5b64a 357 PANTHER PTHR39087 5 350 1.2E-23 T 22-04-2016 HRM2_RS06250 81ebbeabc771759141d92ded4e7255aa 174 PANTHER PTHR30087:SF0 1 169 1.2E-55 T 22-04-2016 HRM2_RS06250 81ebbeabc771759141d92ded4e7255aa 174 Pfam PF04463 Protein of unknown function (DUF523) 7 147 2.7E-38 T 22-04-2016 IPR007553 Domain of unknown function DUF523 HRM2_RS06250 81ebbeabc771759141d92ded4e7255aa 174 PANTHER PTHR30087 1 169 1.2E-55 T 22-04-2016 HRM2_RS11995 ab98c506db8b2c67027e9ac8b04696f6 140 Gene3D G3DSA:2.102.10.10 32 137 4.5E-15 T 22-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 HRM2_RS11995 ab98c506db8b2c67027e9ac8b04696f6 140 SUPERFAMILY SSF50022 38 137 2.23E-16 T 22-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 HRM2_RS11995 ab98c506db8b2c67027e9ac8b04696f6 140 Pfam PF00355 Rieske [2Fe-2S] domain 62 127 2.0E-8 T 22-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 HRM2_RS07440 ccbacc8ccd9353a7fd2fd933e7b74b23 80 SUPERFAMILY SSF54913 1 68 6.67E-5 T 22-04-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta HRM2_RS07440 ccbacc8ccd9353a7fd2fd933e7b74b23 80 Pfam PF09413 Putative prokaryotic signal transducing protein 1 68 3.3E-10 T 22-04-2016 IPR018551 Domain of unknown function DUF2007 HRM2_RS05175 6b4c9d3915299b6a7a11d2b59ca269f7 320 Pfam PF13480 Acetyltransferase (GNAT) domain 152 287 6.2E-19 T 22-04-2016 HRM2_RS05175 6b4c9d3915299b6a7a11d2b59ca269f7 320 Gene3D G3DSA:3.40.630.30 137 279 8.8E-8 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS05175 6b4c9d3915299b6a7a11d2b59ca269f7 320 SUPERFAMILY SSF55729 141 299 8.48E-18 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS08705 ec344dd23518649874d086dfd4eb0094 244 Pfam PF07796 Protein of unknown function (DUF1638) 83 229 2.3E-19 T 22-04-2016 IPR012437 Domain of unknown function DUF1638 HRM2_RS19385 9a7d6a6befd46db40e8afb6a7dee6cb3 619 Pfam PF04055 Radical SAM superfamily 273 434 5.7E-8 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS19385 9a7d6a6befd46db40e8afb6a7dee6cb3 619 SUPERFAMILY SSF102114 235 436 5.23E-24 T 22-04-2016 HRM2_RS19385 9a7d6a6befd46db40e8afb6a7dee6cb3 619 PANTHER PTHR11918 2 437 6.8E-38 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein HRM2_RS19385 9a7d6a6befd46db40e8afb6a7dee6cb3 619 TIGRFAM TIGR03975 rSAM_ocin_1: ribosomal peptide maturation radical SAM protein 1 13 615 8.3E-113 T 22-04-2016 IPR023984 Ribosomal peptide maturation radical SAM protein 1 HRM2_RS19385 9a7d6a6befd46db40e8afb6a7dee6cb3 619 SMART SM00729 265 473 4.9E-8 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS19385 9a7d6a6befd46db40e8afb6a7dee6cb3 619 PANTHER PTHR11918:SF64 2 437 6.8E-38 T 22-04-2016 HRM2_RS19385 9a7d6a6befd46db40e8afb6a7dee6cb3 619 Gene3D G3DSA:3.80.30.20 270 441 2.4E-23 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe HRM2_RS06475 a8dd58df6b304c547e3b771ffadafac4 128 Pfam PF03733 Inner membrane component domain 4 55 3.5E-10 T 22-04-2016 IPR005185 Inner membrane component domain HRM2_RS06475 a8dd58df6b304c547e3b771ffadafac4 128 Pfam PF03733 Inner membrane component domain 73 123 2.0E-16 T 22-04-2016 IPR005185 Inner membrane component domain HRM2_RS06475 a8dd58df6b304c547e3b771ffadafac4 128 PANTHER PTHR31503:SF17 1 123 5.9E-22 T 22-04-2016 HRM2_RS06475 a8dd58df6b304c547e3b771ffadafac4 128 PANTHER PTHR31503 1 123 5.9E-22 T 22-04-2016 HRM2_RS23875 fc5eb5a2641539b2ef9af45ae4813a9e 263 Pfam PF01925 Sulfite exporter TauE/SafE 8 255 5.0E-37 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 HRM2_RS23875 fc5eb5a2641539b2ef9af45ae4813a9e 263 PANTHER PTHR30269 1 263 8.5E-34 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 HRM2_RS18300 f1a9bebb4d37c7908802f4f5d5f4e34c 238 SUPERFAMILY SSF88659 153 227 1.21E-17 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS18300 f1a9bebb4d37c7908802f4f5d5f4e34c 238 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 28 41 - T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS18300 f1a9bebb4d37c7908802f4f5d5f4e34c 238 PIRSF PIRSF000770 1 233 3.7E-36 T 22-04-2016 IPR016263 RNA polymerase sporulation-specific sigma factor GO:0003677|GO:0006351|GO:0016987|GO:0030435 HRM2_RS18300 f1a9bebb4d37c7908802f4f5d5f4e34c 238 SUPERFAMILY SSF88659 75 142 4.27E-10 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS18300 f1a9bebb4d37c7908802f4f5d5f4e34c 238 SUPERFAMILY SSF88946 1 72 1.13E-18 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS18300 f1a9bebb4d37c7908802f4f5d5f4e34c 238 PANTHER PTHR30385 1 226 1.3E-48 T 22-04-2016 HRM2_RS18300 f1a9bebb4d37c7908802f4f5d5f4e34c 238 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 195 221 - T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS18300 f1a9bebb4d37c7908802f4f5d5f4e34c 238 Gene3D G3DSA:1.10.10.10 170 225 4.9E-12 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS18300 f1a9bebb4d37c7908802f4f5d5f4e34c 238 PRINTS PR00046 Major sigma-70 factor signature 178 190 1.5E-11 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS18300 f1a9bebb4d37c7908802f4f5d5f4e34c 238 PRINTS PR00046 Major sigma-70 factor signature 210 221 1.5E-11 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS18300 f1a9bebb4d37c7908802f4f5d5f4e34c 238 PRINTS PR00046 Major sigma-70 factor signature 195 210 1.5E-11 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS18300 f1a9bebb4d37c7908802f4f5d5f4e34c 238 PRINTS PR00046 Major sigma-70 factor signature 28 41 1.5E-11 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS18300 f1a9bebb4d37c7908802f4f5d5f4e34c 238 Gene3D G3DSA:1.10.601.10 1 65 3.6E-14 T 22-04-2016 HRM2_RS18300 f1a9bebb4d37c7908802f4f5d5f4e34c 238 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 2 225 7.3E-71 T 22-04-2016 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 HRM2_RS18300 f1a9bebb4d37c7908802f4f5d5f4e34c 238 Pfam PF04542 Sigma-70 region 2 4 70 3.7E-12 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS18300 f1a9bebb4d37c7908802f4f5d5f4e34c 238 PANTHER PTHR30385:SF7 1 226 1.3E-48 T 22-04-2016 HRM2_RS18300 f1a9bebb4d37c7908802f4f5d5f4e34c 238 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 224 6.3E-30 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS18300 f1a9bebb4d37c7908802f4f5d5f4e34c 238 Pfam PF04545 Sigma-70, region 4 176 222 1.6E-14 T 22-04-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HRM2_RS20695 385061c27ae3c50fc049daf31ebb9f20 157 SUPERFAMILY SSF47240 3 151 1.79E-18 T 22-04-2016 IPR009078 Ferritin-like superfamily HRM2_RS20695 385061c27ae3c50fc049daf31ebb9f20 157 PANTHER PTHR33531 1 149 1.1E-19 T 22-04-2016 HRM2_RS20695 385061c27ae3c50fc049daf31ebb9f20 157 Gene3D G3DSA:1.20.1260.10 1 150 5.4E-31 T 22-04-2016 IPR012347 Ferritin-related HRM2_RS20695 385061c27ae3c50fc049daf31ebb9f20 157 Pfam PF02915 Rubrerythrin 9 149 1.4E-8 T 22-04-2016 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 HRM2_RS20695 385061c27ae3c50fc049daf31ebb9f20 157 PANTHER PTHR33531:SF1 1 149 1.1E-19 T 22-04-2016 HRM2_RS02760 c130f273aead88a3a67a09951923eed4 397 PANTHER PTHR23502 11 353 2.7E-63 T 22-04-2016 HRM2_RS02760 c130f273aead88a3a67a09951923eed4 397 Gene3D G3DSA:1.20.1250.20 15 192 1.5E-30 T 22-04-2016 HRM2_RS02760 c130f273aead88a3a67a09951923eed4 397 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 13 383 5.1E-64 T 22-04-2016 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 HRM2_RS02760 c130f273aead88a3a67a09951923eed4 397 SUPERFAMILY SSF103473 8 386 1.96E-51 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS02760 c130f273aead88a3a67a09951923eed4 397 PANTHER PTHR23502:SF19 11 353 2.7E-63 T 22-04-2016 HRM2_RS02760 c130f273aead88a3a67a09951923eed4 397 Pfam PF07690 Major Facilitator Superfamily 21 355 9.7E-35 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS09045 5437a6683dc9769f87c726554c9410c3 349 Gene3D G3DSA:3.40.50.2000 176 316 2.0E-4 T 22-04-2016 HRM2_RS09045 5437a6683dc9769f87c726554c9410c3 349 PIRSF PIRSF028458 1 349 9.3E-133 T 22-04-2016 IPR016886 Predicted glycerophosphotransferase UCP028458 HRM2_RS09045 5437a6683dc9769f87c726554c9410c3 349 SUPERFAMILY SSF53756 44 322 2.93E-30 T 22-04-2016 HRM2_RS09045 5437a6683dc9769f87c726554c9410c3 349 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 130 315 3.1E-10 T 22-04-2016 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain HRM2_RS21780 427d6e1e36389ddb9049230c6263aba0 502 PANTHER PTHR30290 33 502 1.5E-96 T 22-04-2016 HRM2_RS21780 427d6e1e36389ddb9049230c6263aba0 502 Gene3D G3DSA:3.40.190.10 181 284 1.7E-21 T 22-04-2016 HRM2_RS21780 427d6e1e36389ddb9049230c6263aba0 502 PIRSF PIRSF002741 20 499 3.3E-79 T 22-04-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 HRM2_RS21780 427d6e1e36389ddb9049230c6263aba0 502 SUPERFAMILY SSF53850 34 486 1.55E-111 T 22-04-2016 HRM2_RS21780 427d6e1e36389ddb9049230c6263aba0 502 Gene3D G3DSA:3.90.76.10 41 180 1.9E-38 T 22-04-2016 HRM2_RS21780 427d6e1e36389ddb9049230c6263aba0 502 Gene3D G3DSA:3.10.105.10 285 469 1.2E-35 T 22-04-2016 HRM2_RS21780 427d6e1e36389ddb9049230c6263aba0 502 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 73 421 5.3E-76 T 22-04-2016 IPR000914 Solute-binding protein family 5 domain HRM2_RS06965 af7ed94c962e6b20598b386e7d4a437a 478 PANTHER PTHR32479:SF10 41 475 8.9E-142 T 22-04-2016 HRM2_RS06965 af7ed94c962e6b20598b386e7d4a437a 478 Pfam PF02589 Uncharacterised ACR, YkgG family COG1556 73 292 6.0E-46 T 22-04-2016 IPR003741 LUD domain HRM2_RS06965 af7ed94c962e6b20598b386e7d4a437a 478 Pfam PF13183 4Fe-4S dicluster domain 308 374 1.1E-7 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS06965 af7ed94c962e6b20598b386e7d4a437a 478 Pfam PF11870 Domain of unknown function (DUF3390) 399 474 3.5E-7 T 22-04-2016 IPR024569 4Fe-4S binding protein, C-terminal HRM2_RS06965 af7ed94c962e6b20598b386e7d4a437a 478 Gene3D G3DSA:1.10.1060.10 295 389 7.3E-8 T 22-04-2016 HRM2_RS06965 af7ed94c962e6b20598b386e7d4a437a 478 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 16 458 2.0E-140 T 22-04-2016 IPR004452 4Fe-4S binding protein GO:0019516 HRM2_RS06965 af7ed94c962e6b20598b386e7d4a437a 478 SUPERFAMILY SSF100950 64 87 4.18E-33 T 22-04-2016 HRM2_RS06965 af7ed94c962e6b20598b386e7d4a437a 478 SUPERFAMILY SSF100950 133 293 4.18E-33 T 22-04-2016 HRM2_RS06965 af7ed94c962e6b20598b386e7d4a437a 478 Gene3D G3DSA:3.40.50.10420 187 293 3.6E-41 T 22-04-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain HRM2_RS06965 af7ed94c962e6b20598b386e7d4a437a 478 Gene3D G3DSA:3.40.50.10420 63 126 3.6E-41 T 22-04-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain HRM2_RS06965 af7ed94c962e6b20598b386e7d4a437a 478 PANTHER PTHR32479 41 475 8.9E-142 T 22-04-2016 HRM2_RS06965 af7ed94c962e6b20598b386e7d4a437a 478 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 311 322 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS06965 af7ed94c962e6b20598b386e7d4a437a 478 SUPERFAMILY SSF54862 289 404 9.63E-12 T 22-04-2016 HRM2_RS10485 08f7a082d46517a21f611cb44c318856 666 Pfam PF13533 Biotin-lipoyl like 57 92 1.3E-5 T 22-04-2016 HRM2_RS10485 08f7a082d46517a21f611cb44c318856 666 PANTHER PTHR32347 13 332 5.3E-15 T 22-04-2016 HRM2_RS10485 08f7a082d46517a21f611cb44c318856 666 Gene3D G3DSA:2.40.50.100 56 79 9.6E-10 T 22-04-2016 HRM2_RS10485 08f7a082d46517a21f611cb44c318856 666 Gene3D G3DSA:2.40.50.100 220 251 9.6E-10 T 22-04-2016 HRM2_RS23940 f8814db1969455532b474bc930219e19 240 Gene3D G3DSA:2.160.10.10 33 217 4.7E-38 T 22-04-2016 HRM2_RS23940 f8814db1969455532b474bc930219e19 240 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 145 173 - T 22-04-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 HRM2_RS23940 f8814db1969455532b474bc930219e19 240 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 137 170 4.9E-9 T 22-04-2016 IPR001451 Hexapeptide repeat HRM2_RS23940 f8814db1969455532b474bc930219e19 240 SUPERFAMILY SSF51161 44 198 1.08E-35 T 22-04-2016 IPR011004 Trimeric LpxA-like HRM2_RS23940 f8814db1969455532b474bc930219e19 240 PANTHER PTHR23416 82 194 4.9E-29 T 22-04-2016 HRM2_RS23940 f8814db1969455532b474bc930219e19 240 PANTHER PTHR23416:SF23 82 194 4.9E-29 T 22-04-2016 HRM2_RS17395 32935acfc5a99965869892db0a32fab6 367 PANTHER PTHR30474 3 363 1.7E-144 T 22-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 HRM2_RS17395 32935acfc5a99965869892db0a32fab6 367 Pfam PF01098 Cell cycle protein 14 362 4.3E-106 T 22-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 HRM2_RS17395 32935acfc5a99965869892db0a32fab6 367 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 321 345 - T 22-04-2016 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 HRM2_RS17395 32935acfc5a99965869892db0a32fab6 367 PANTHER PTHR30474:SF1 3 363 1.7E-144 T 22-04-2016 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 HRM2_RS17395 32935acfc5a99965869892db0a32fab6 367 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 11 363 2.3E-129 T 22-04-2016 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 HRM2_RS02755 240d6fd56514349b151f18ed55b391ec 774 Pfam PF01136 Peptidase family U32 79 291 4.4E-63 T 22-04-2016 IPR001539 Peptidase U32 GO:0006508|GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- HRM2_RS02755 240d6fd56514349b151f18ed55b391ec 774 PANTHER PTHR30217 1 323 3.2E-105 T 22-04-2016 HRM2_RS02755 240d6fd56514349b151f18ed55b391ec 774 PANTHER PTHR30217:SF10 1 323 3.2E-105 T 22-04-2016 HRM2_RS21075 9c4366fbcb0b00d19969cbdf6872a592 362 SUPERFAMILY SSF54909 272 350 4.29E-10 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel HRM2_RS21075 9c4366fbcb0b00d19969cbdf6872a592 362 SMART SM00470 42 142 1.8E-6 T 22-04-2016 IPR003115 ParB/Sulfiredoxin HRM2_RS21075 9c4366fbcb0b00d19969cbdf6872a592 362 Pfam PF01037 Lrp/AsnC ligand binding domain 278 350 9.2E-6 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain HRM2_RS21075 9c4366fbcb0b00d19969cbdf6872a592 362 Gene3D G3DSA:3.30.70.920 274 350 8.9E-21 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain HRM2_RS21075 9c4366fbcb0b00d19969cbdf6872a592 362 Gene3D G3DSA:3.90.1530.10 62 134 6.0E-14 T 22-04-2016 HRM2_RS21075 9c4366fbcb0b00d19969cbdf6872a592 362 SUPERFAMILY SSF110849 65 126 2.35E-13 T 22-04-2016 IPR003115 ParB/Sulfiredoxin HRM2_RS21075 9c4366fbcb0b00d19969cbdf6872a592 362 Pfam PF02195 ParB-like nuclease domain 61 127 1.9E-11 T 22-04-2016 IPR003115 ParB/Sulfiredoxin HRM2_RS16430 4e3beca7b8ae21f28a692ab5ddc2a12e 422 PIRSF PIRSF006066 1 422 1.4E-97 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS16430 4e3beca7b8ae21f28a692ab5ddc2a12e 422 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 6 416 6.5E-79 T 22-04-2016 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit HRM2_RS16430 4e3beca7b8ae21f28a692ab5ddc2a12e 422 PANTHER PTHR33362 5 418 2.1E-79 T 22-04-2016 HRM2_RS16430 4e3beca7b8ae21f28a692ab5ddc2a12e 422 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 16 420 3.0E-102 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS16430 4e3beca7b8ae21f28a692ab5ddc2a12e 422 PANTHER PTHR33362:SF6 5 418 2.1E-79 T 22-04-2016 HRM2_RS08100 6e64fff1620b36c19123db999b652006 401 Pfam PF02687 FtsX-like permease family 282 394 8.8E-22 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 HRM2_RS08100 6e64fff1620b36c19123db999b652006 401 PANTHER PTHR30572 1 401 1.2E-137 T 22-04-2016 HRM2_RS08100 6e64fff1620b36c19123db999b652006 401 Pfam PF12704 MacB-like periplasmic core domain 20 236 1.8E-38 T 22-04-2016 IPR025857 MacB-like periplasmic core domain HRM2_RS08100 6e64fff1620b36c19123db999b652006 401 PANTHER PTHR30572:SF9 1 401 1.2E-137 T 22-04-2016 HRM2_RS24390 c5fcba33374ee507e0ffcc8a84c49489 114 SMART SM01078 3 111 1.4E-5 T 22-04-2016 IPR014925 Uncharacterised domain CGGC-dom HRM2_RS24390 c5fcba33374ee507e0ffcc8a84c49489 114 Pfam PF08821 CGGC domain 3 111 1.8E-22 T 22-04-2016 IPR014925 Uncharacterised domain CGGC-dom HRM2_RS07640 bcdbb7dae325ae960ee652597f5c0874 775 PANTHER PTHR32282 61 730 2.3E-223 T 22-04-2016 HRM2_RS07640 bcdbb7dae325ae960ee652597f5c0874 775 TIGRFAM TIGR02071 PBP_1b: penicillin-binding protein 1B 13 727 2.6E-251 T 22-04-2016 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00500+2.4.1.12|KEGG: 00550+3.4.-.-+2.4.1.129|KEGG: 00780+3.4.-.-|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HRM2_RS07640 bcdbb7dae325ae960ee652597f5c0874 775 Pfam PF00905 Penicillin binding protein transpeptidase domain 410 655 3.4E-24 T 22-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 HRM2_RS07640 bcdbb7dae325ae960ee652597f5c0874 775 Pfam PF14814 Bifunctional transglycosylase second domain 51 137 6.1E-22 T 22-04-2016 IPR028166 Bifunctional transglycosylase second domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00500+2.4.1.12|KEGG: 00550+3.4.-.-+2.4.1.129|KEGG: 00780+3.4.-.-|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HRM2_RS07640 bcdbb7dae325ae960ee652597f5c0874 775 Gene3D G3DSA:1.10.3810.10 150 321 1.1E-65 T 22-04-2016 HRM2_RS07640 bcdbb7dae325ae960ee652597f5c0874 775 Pfam PF00912 Transglycosylase 149 320 2.2E-59 T 22-04-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 HRM2_RS07640 bcdbb7dae325ae960ee652597f5c0874 775 SUPERFAMILY SSF53955 140 345 1.69E-66 T 22-04-2016 IPR023346 Lysozyme-like domain HRM2_RS07640 bcdbb7dae325ae960ee652597f5c0874 775 Gene3D G3DSA:3.30.2060.10 48 139 9.4E-19 T 22-04-2016 HRM2_RS07640 bcdbb7dae325ae960ee652597f5c0874 775 PANTHER PTHR32282:SF11 61 730 2.3E-223 T 22-04-2016 HRM2_RS07640 bcdbb7dae325ae960ee652597f5c0874 775 SUPERFAMILY SSF56601 353 736 1.94E-117 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HRM2_RS07640 bcdbb7dae325ae960ee652597f5c0874 775 SUPERFAMILY SSF56601 302 324 1.94E-117 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HRM2_RS07640 bcdbb7dae325ae960ee652597f5c0874 775 Gene3D G3DSA:3.40.710.10 322 733 2.3E-110 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HRM2_RS07640 bcdbb7dae325ae960ee652597f5c0874 775 PIRSF PIRSF002799 1 775 2.9E-278 T 22-04-2016 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00500+2.4.1.12|KEGG: 00550+3.4.-.-+2.4.1.129|KEGG: 00780+3.4.-.-|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HRM2_RS08085 49bb5945e423aa47cde877d8d1ba795a 513 Gene3D G3DSA:1.20.1600.10 94 503 6.1E-101 T 22-04-2016 HRM2_RS08085 49bb5945e423aa47cde877d8d1ba795a 513 PANTHER PTHR30203 24 505 2.3E-135 T 22-04-2016 HRM2_RS08085 49bb5945e423aa47cde877d8d1ba795a 513 PANTHER PTHR30203:SF3 24 505 2.3E-135 T 22-04-2016 HRM2_RS08085 49bb5945e423aa47cde877d8d1ba795a 513 SUPERFAMILY SSF56954 97 503 5.75E-95 T 22-04-2016 HRM2_RS08085 49bb5945e423aa47cde877d8d1ba795a 513 SUPERFAMILY SSF56954 41 73 5.75E-95 T 22-04-2016 HRM2_RS08085 49bb5945e423aa47cde877d8d1ba795a 513 Pfam PF02321 Outer membrane efflux protein 109 287 9.5E-24 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS08085 49bb5945e423aa47cde877d8d1ba795a 513 Pfam PF02321 Outer membrane efflux protein 319 498 5.3E-18 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS08085 49bb5945e423aa47cde877d8d1ba795a 513 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 49 500 3.7E-99 T 22-04-2016 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 HRM2_RS19520 bff87d25b1408a124a0959a543ec8b11 430 Gene3D G3DSA:3.30.300.20 287 428 5.1E-21 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta HRM2_RS19520 bff87d25b1408a124a0959a543ec8b11 430 Gene3D G3DSA:3.30.300.20 92 215 4.0E-9 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta HRM2_RS19520 bff87d25b1408a124a0959a543ec8b11 430 Pfam PF02566 OsmC-like protein 316 419 7.9E-7 T 22-04-2016 IPR003718 OsmC/Ohr family HRM2_RS19520 bff87d25b1408a124a0959a543ec8b11 430 SUPERFAMILY SSF82784 97 207 1.96E-5 T 22-04-2016 IPR003718 OsmC/Ohr family HRM2_RS19520 bff87d25b1408a124a0959a543ec8b11 430 SUPERFAMILY SSF82784 301 421 1.31E-9 T 22-04-2016 IPR003718 OsmC/Ohr family HRM2_RS10630 78783071e7f1366c2fcd099dddfddc3f 186 SUPERFAMILY SSF53323 10 184 1.83E-32 T 22-04-2016 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 HRM2_RS10630 78783071e7f1366c2fcd099dddfddc3f 186 PANTHER PTHR32154:SF22 10 168 1.8E-34 T 22-04-2016 HRM2_RS10630 78783071e7f1366c2fcd099dddfddc3f 186 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 20 179 3.9E-27 T 22-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HRM2_RS10630 78783071e7f1366c2fcd099dddfddc3f 186 Gene3D G3DSA:3.40.920.10 10 184 1.2E-28 T 22-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HRM2_RS10630 78783071e7f1366c2fcd099dddfddc3f 186 PANTHER PTHR32154 10 168 1.8E-34 T 22-04-2016 HRM2_RS20515 55533b9fbb1b60e098c95f7c19dcd661 419 PANTHER PTHR23530 10 410 3.0E-48 T 22-04-2016 HRM2_RS20515 55533b9fbb1b60e098c95f7c19dcd661 419 PANTHER PTHR23530:SF1 10 410 3.0E-48 T 22-04-2016 HRM2_RS20515 55533b9fbb1b60e098c95f7c19dcd661 419 Pfam PF07690 Major Facilitator Superfamily 45 351 3.7E-17 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS20515 55533b9fbb1b60e098c95f7c19dcd661 419 Gene3D G3DSA:1.20.1250.20 31 198 1.6E-17 T 22-04-2016 HRM2_RS20515 55533b9fbb1b60e098c95f7c19dcd661 419 Gene3D G3DSA:1.20.1250.20 229 397 5.8E-12 T 22-04-2016 HRM2_RS20515 55533b9fbb1b60e098c95f7c19dcd661 419 SUPERFAMILY SSF103473 31 399 1.31E-40 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS04790 8534bc082985fae597769fa63ff4b32f 468 PANTHER PTHR33712 227 459 3.1E-93 T 22-04-2016 HRM2_RS04790 8534bc082985fae597769fa63ff4b32f 468 PANTHER PTHR33712 5 208 3.1E-93 T 22-04-2016 HRM2_RS04790 8534bc082985fae597769fa63ff4b32f 468 Gene3D G3DSA:3.40.50.1980 306 429 1.9E-38 T 22-04-2016 HRM2_RS04790 8534bc082985fae597769fa63ff4b32f 468 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 25 453 1.6E-116 T 22-04-2016 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 HRM2_RS04790 8534bc082985fae597769fa63ff4b32f 468 Gene3D G3DSA:3.40.50.1980 25 159 3.2E-48 T 22-04-2016 HRM2_RS04790 8534bc082985fae597769fa63ff4b32f 468 SUPERFAMILY SSF53807 17 457 2.81E-123 T 22-04-2016 HRM2_RS04790 8534bc082985fae597769fa63ff4b32f 468 Gene3D G3DSA:3.40.50.1980 172 276 4.2E-31 T 22-04-2016 HRM2_RS04790 8534bc082985fae597769fa63ff4b32f 468 ProSitePatterns PS00699 Nitrogenases component 1 alpha and beta subunits signature 1. 43 50 - T 22-04-2016 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 HRM2_RS04790 8534bc082985fae597769fa63ff4b32f 468 PANTHER PTHR33712:SF2 227 459 3.1E-93 T 22-04-2016 HRM2_RS04790 8534bc082985fae597769fa63ff4b32f 468 PANTHER PTHR33712:SF2 5 208 3.1E-93 T 22-04-2016 HRM2_RS16115 f71b1ba6c11a35e635997d4774bd3ad7 242 Pfam PF13279 Thioesterase-like superfamily 113 231 6.4E-6 T 22-04-2016 HRM2_RS16115 f71b1ba6c11a35e635997d4774bd3ad7 242 SUPERFAMILY SSF54637 103 232 4.61E-21 T 22-04-2016 IPR029069 HotDog domain HRM2_RS16115 f71b1ba6c11a35e635997d4774bd3ad7 242 Gene3D G3DSA:3.10.129.10 104 236 4.2E-21 T 22-04-2016 IPR029069 HotDog domain HRM2_RS23390 29735dc57cdccef837b5808c28f3a90f 225 SUPERFAMILY SSF53335 45 149 4.85E-9 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS23390 29735dc57cdccef837b5808c28f3a90f 225 Pfam PF13679 Methyltransferase domain 48 163 1.3E-6 T 22-04-2016 IPR025714 Methyltransferase domain HRM2_RS23390 29735dc57cdccef837b5808c28f3a90f 225 PANTHER PTHR13369 26 223 1.2E-23 T 22-04-2016 HRM2_RS23390 29735dc57cdccef837b5808c28f3a90f 225 Gene3D G3DSA:3.40.50.150 45 136 1.1E-5 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS25305 b738e31109bbc65708bf18bd8bc92909 143 Pfam PF00041 Fibronectin type III domain 44 134 2.9E-7 T 22-04-2016 IPR003961 Fibronectin type III GO:0005515 HRM2_RS25305 b738e31109bbc65708bf18bd8bc92909 143 SUPERFAMILY SSF49265 43 141 7.3E-12 T 22-04-2016 IPR003961 Fibronectin type III GO:0005515 HRM2_RS25305 b738e31109bbc65708bf18bd8bc92909 143 Gene3D G3DSA:2.60.40.10 43 141 1.1E-9 T 22-04-2016 IPR013783 Immunoglobulin-like fold HRM2_RS05290 39280ae4c48605b8638ba25504026d4a 379 Gene3D G3DSA:2.40.110.10 121 217 4.0E-39 T 22-04-2016 HRM2_RS05290 39280ae4c48605b8638ba25504026d4a 379 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 2.4E-27 T 22-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 HRM2_RS05290 39280ae4c48605b8638ba25504026d4a 379 PANTHER PTHR10909:SF10 1 379 4.9E-174 T 22-04-2016 HRM2_RS05290 39280ae4c48605b8638ba25504026d4a 379 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 22-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 HRM2_RS05290 39280ae4c48605b8638ba25504026d4a 379 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 1.8E-55 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS05290 39280ae4c48605b8638ba25504026d4a 379 PIRSF PIRSF016578 6 367 5.4E-23 T 22-04-2016 HRM2_RS05290 39280ae4c48605b8638ba25504026d4a 379 SUPERFAMILY SSF47203 228 379 2.09E-61 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS05290 39280ae4c48605b8638ba25504026d4a 379 SUPERFAMILY SSF56645 2 242 4.45E-86 T 22-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 HRM2_RS05290 39280ae4c48605b8638ba25504026d4a 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 2.3E-35 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS05290 39280ae4c48605b8638ba25504026d4a 379 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 22-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 HRM2_RS05290 39280ae4c48605b8638ba25504026d4a 379 Gene3D G3DSA:1.10.540.10 1 120 3.0E-42 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS05290 39280ae4c48605b8638ba25504026d4a 379 PANTHER PTHR10909 1 379 4.9E-174 T 22-04-2016 HRM2_RS05290 39280ae4c48605b8638ba25504026d4a 379 Gene3D G3DSA:1.20.140.10 218 379 6.1E-75 T 22-04-2016 HRM2_RS16560 d7cdee8e1ff835dd629fe206893ee688 330 Pfam PF09084 NMT1/THI5 like 39 248 6.9E-49 T 22-04-2016 IPR015168 SsuA/THI5-like HRM2_RS16560 d7cdee8e1ff835dd629fe206893ee688 330 PANTHER PTHR31528 28 322 4.0E-41 T 22-04-2016 IPR027939 NMT1/THI5 family GO:0009228 UniPathway: UPA00060 HRM2_RS16560 d7cdee8e1ff835dd629fe206893ee688 330 Gene3D G3DSA:3.40.190.10 123 239 3.6E-10 T 22-04-2016 HRM2_RS16560 d7cdee8e1ff835dd629fe206893ee688 330 SUPERFAMILY SSF53850 37 261 8.39E-25 T 22-04-2016 HRM2_RS23800 2bc7c87550adc6a423228af7ef32d386 641 Gene3D G3DSA:3.30.565.10 6 260 2.8E-77 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS23800 2bc7c87550adc6a423228af7ef32d386 641 SUPERFAMILY SSF54211 253 503 8.34E-92 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HRM2_RS23800 2bc7c87550adc6a423228af7ef32d386 641 PANTHER PTHR11528:SF44 3 641 8.2E-287 T 22-04-2016 HRM2_RS23800 2bc7c87550adc6a423228af7ef32d386 641 Hamap MF_00505 Chaperone protein HtpG [htpG]. 3 638 29.075 T 22-04-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 HRM2_RS23800 2bc7c87550adc6a423228af7ef32d386 641 SUPERFAMILY SSF55874 6 219 1.31E-61 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS23800 2bc7c87550adc6a423228af7ef32d386 641 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 28 184 5.7E-12 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS23800 2bc7c87550adc6a423228af7ef32d386 641 SUPERFAMILY SSF110942 521 638 2.35E-30 T 22-04-2016 HRM2_RS23800 2bc7c87550adc6a423228af7ef32d386 641 PANTHER PTHR11528 3 641 8.2E-287 T 22-04-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 HRM2_RS23800 2bc7c87550adc6a423228af7ef32d386 641 PRINTS PR00775 90kDa heat shock protein signature 195 213 6.3E-58 T 22-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal HRM2_RS23800 2bc7c87550adc6a423228af7ef32d386 641 PRINTS PR00775 90kDa heat shock protein signature 124 146 6.3E-58 T 22-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal HRM2_RS23800 2bc7c87550adc6a423228af7ef32d386 641 PRINTS PR00775 90kDa heat shock protein signature 174 191 6.3E-58 T 22-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal HRM2_RS23800 2bc7c87550adc6a423228af7ef32d386 641 PRINTS PR00775 90kDa heat shock protein signature 27 49 6.3E-58 T 22-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal HRM2_RS23800 2bc7c87550adc6a423228af7ef32d386 641 PRINTS PR00775 90kDa heat shock protein signature 76 93 6.3E-58 T 22-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal HRM2_RS23800 2bc7c87550adc6a423228af7ef32d386 641 PRINTS PR00775 90kDa heat shock protein signature 6 26 6.3E-58 T 22-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal HRM2_RS23800 2bc7c87550adc6a423228af7ef32d386 641 PRINTS PR00775 90kDa heat shock protein signature 94 111 6.3E-58 T 22-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal HRM2_RS23800 2bc7c87550adc6a423228af7ef32d386 641 PIRSF PIRSF002583 1 641 4.7E-210 T 22-04-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 HRM2_RS23800 2bc7c87550adc6a423228af7ef32d386 641 Pfam PF00183 Hsp90 protein 191 641 1.9E-136 T 22-04-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 HRM2_RS07165 4a9473de8af19fff392c3dc983820117 146 SUPERFAMILY SSF46548 14 90 3.84E-12 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS07165 4a9473de8af19fff392c3dc983820117 146 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 14 25 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS07165 4a9473de8af19fff392c3dc983820117 146 Pfam PF13183 4Fe-4S dicluster domain 14 75 7.1E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS07165 4a9473de8af19fff392c3dc983820117 146 Gene3D G3DSA:1.10.1060.10 14 92 6.1E-11 T 22-04-2016 HRM2_RS19165 7bca8024cd64efa3b871c0a9f430b58e 168 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 26 156 1.4E-22 T 22-04-2016 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component HRM2_RS19165 7bca8024cd64efa3b871c0a9f430b58e 168 PANTHER PTHR35011 1 148 9.1E-17 T 22-04-2016 HRM2_RS15690 de12b5a55078e28c07dc5df5f248b877 171 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 20 130 6.4E-22 T 22-04-2016 IPR029464 Type I restriction enzyme R protein, N-terminal domain HRM2_RS03360 cdba2e6b41fff7aaee54ce592187c73a 386 PANTHER PTHR30578 4 386 4.3E-152 T 22-04-2016 HRM2_RS03360 cdba2e6b41fff7aaee54ce592187c73a 386 PANTHER PTHR30578:SF1 4 386 4.3E-152 T 22-04-2016 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 HRM2_RS03360 cdba2e6b41fff7aaee54ce592187c73a 386 Hamap MF_00426 Na(+)-translocating NADH-quinone reductase subunit B [nqrB]. 3 386 33.529 T 22-04-2016 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 HRM2_RS03360 cdba2e6b41fff7aaee54ce592187c73a 386 Pfam PF03116 NQR2, RnfD, RnfE family 45 376 1.1E-98 T 22-04-2016 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 HRM2_RS03360 cdba2e6b41fff7aaee54ce592187c73a 386 TIGRFAM TIGR01937 nqrB: NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit 88 379 1.1E-108 T 22-04-2016 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 HRM2_RS23845 989db38f3eb1fd1a604d8264b65974c6 390 PANTHER PTHR34184 229 387 2.5E-144 T 22-04-2016 HRM2_RS23845 989db38f3eb1fd1a604d8264b65974c6 390 PANTHER PTHR34184 13 211 2.5E-144 T 22-04-2016 HRM2_RS23845 989db38f3eb1fd1a604d8264b65974c6 390 PANTHER PTHR34184:SF3 229 387 2.5E-144 T 22-04-2016 HRM2_RS23845 989db38f3eb1fd1a604d8264b65974c6 390 PANTHER PTHR34184:SF3 13 211 2.5E-144 T 22-04-2016 HRM2_RS23845 989db38f3eb1fd1a604d8264b65974c6 390 Pfam PF03773 Predicted permease 33 386 1.6E-78 T 22-04-2016 IPR005524 Predicted permease DUF318 HRM2_RS05090 c2fb4b01906f33cc33f3881d79906a59 192 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 130 4.5E-13 T 22-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain HRM2_RS05090 c2fb4b01906f33cc33f3881d79906a59 192 SUPERFAMILY SSF54593 3 146 2.15E-30 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HRM2_RS05090 c2fb4b01906f33cc33f3881d79906a59 192 Gene3D G3DSA:3.10.180.10 2 149 2.3E-36 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HRM2_RS13445 98bc1b211f2506b917d3947bbc149e60 96 Pfam PF04977 Septum formation initiator 17 96 1.1E-18 T 22-04-2016 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 HRM2_RS22555 f251ba1f6e44509b086727d056a18cdb 297 PANTHER PTHR30128 153 297 4.7E-14 T 22-04-2016 HRM2_RS22555 f251ba1f6e44509b086727d056a18cdb 297 Gene3D G3DSA:3.30.1330.60 172 292 3.8E-18 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS22555 f251ba1f6e44509b086727d056a18cdb 297 Pfam PF00691 OmpA family 190 273 4.9E-11 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS22555 f251ba1f6e44509b086727d056a18cdb 297 SUPERFAMILY SSF103088 179 292 1.19E-18 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS08235 0c28578cea079f266763b72be93bc46b 371 PANTHER PTHR13615 1 364 5.3E-84 T 22-04-2016 HRM2_RS08235 0c28578cea079f266763b72be93bc46b 371 Gene3D G3DSA:3.40.50.2000 177 341 3.7E-10 T 22-04-2016 HRM2_RS08235 0c28578cea079f266763b72be93bc46b 371 PANTHER PTHR13615:SF3 1 364 5.3E-84 T 22-04-2016 HRM2_RS08235 0c28578cea079f266763b72be93bc46b 371 Pfam PF00534 Glycosyl transferases group 1 185 335 1.4E-9 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 HRM2_RS08235 0c28578cea079f266763b72be93bc46b 371 Pfam PF12038 Domain of unknown function (DUF3524) 3 166 6.5E-57 T 22-04-2016 IPR022701 Glycosyltransferase family 1, N-terminal HRM2_RS08235 0c28578cea079f266763b72be93bc46b 371 SUPERFAMILY SSF53756 21 359 3.92E-29 T 22-04-2016 HRM2_RS22395 01bd2883cb2644c0432bc2333f7a28ef 427 PANTHER PTHR15362:SF2 213 338 4.3E-17 T 22-04-2016 HRM2_RS22395 01bd2883cb2644c0432bc2333f7a28ef 427 PANTHER PTHR15362 213 338 4.3E-17 T 22-04-2016 HRM2_RS22395 01bd2883cb2644c0432bc2333f7a28ef 427 Pfam PF01066 CDP-alcohol phosphatidyltransferase 212 273 4.5E-7 T 22-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 HRM2_RS22395 01bd2883cb2644c0432bc2333f7a28ef 427 Pfam PF01066 CDP-alcohol phosphatidyltransferase 42 106 3.8E-11 T 22-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 HRM2_RS22395 01bd2883cb2644c0432bc2333f7a28ef 427 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 84 106 - T 22-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 HRM2_RS14220 ad54743dfac28da0b989c67ee7fc7e93 610 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 11 431 4.0E-108 T 22-04-2016 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978|UniPathway: UPA00232 HRM2_RS14220 ad54743dfac28da0b989c67ee7fc7e93 610 SUPERFAMILY SSF143968 502 603 1.7E-11 T 22-04-2016 HRM2_RS14220 ad54743dfac28da0b989c67ee7fc7e93 610 PANTHER PTHR30108:SF7 1 498 1.9E-190 T 22-04-2016 HRM2_RS14220 ad54743dfac28da0b989c67ee7fc7e93 610 Gene3D G3DSA:3.40.1670.10 502 576 7.6E-6 T 22-04-2016 HRM2_RS14220 ad54743dfac28da0b989c67ee7fc7e93 610 Gene3D G3DSA:3.40.1670.10 334 455 2.9E-15 T 22-04-2016 HRM2_RS14220 ad54743dfac28da0b989c67ee7fc7e93 610 SUPERFAMILY SSF143968 316 455 7.32E-24 T 22-04-2016 HRM2_RS14220 ad54743dfac28da0b989c67ee7fc7e93 610 PANTHER PTHR30108 1 498 1.9E-190 T 22-04-2016 HRM2_RS14220 ad54743dfac28da0b989c67ee7fc7e93 610 SUPERFAMILY SSF50475 3 315 3.22E-84 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 HRM2_RS19495 897663db6aed1351eaa58943254c273c 117 Pfam PF05717 IS66 Orf2 like protein 9 106 5.3E-42 T 22-04-2016 IPR008878 Transposase IS66, Orf2 HRM2_RS19495 897663db6aed1351eaa58943254c273c 117 PANTHER PTHR36455:SF1 2 113 2.2E-37 T 22-04-2016 HRM2_RS19495 897663db6aed1351eaa58943254c273c 117 PANTHER PTHR36455 2 113 2.2E-37 T 22-04-2016 HRM2_RS04865 6806e8bc7fab288d7af43de7814d940f 153 SUPERFAMILY SSF55729 6 145 2.36E-25 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS04865 6806e8bc7fab288d7af43de7814d940f 153 PANTHER PTHR23091 1 139 3.6E-15 T 22-04-2016 HRM2_RS04865 6806e8bc7fab288d7af43de7814d940f 153 Pfam PF00583 Acetyltransferase (GNAT) family 61 141 1.1E-12 T 22-04-2016 IPR000182 GNAT domain GO:0008080 HRM2_RS04865 6806e8bc7fab288d7af43de7814d940f 153 Gene3D G3DSA:3.40.630.30 7 139 2.1E-26 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS13310 49d2d6fe1e132f57e483722e9db14643 320 PANTHER PTHR21621 135 315 6.5E-28 T 22-04-2016 HRM2_RS13310 49d2d6fe1e132f57e483722e9db14643 320 Pfam PF08443 RimK-like ATP-grasp domain 134 311 5.8E-25 T 22-04-2016 IPR013651 ATP-grasp fold, RimK-type HRM2_RS13310 49d2d6fe1e132f57e483722e9db14643 320 Gene3D G3DSA:3.30.1490.20 131 208 1.6E-6 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HRM2_RS13310 49d2d6fe1e132f57e483722e9db14643 320 Gene3D G3DSA:3.30.470.20 209 295 1.4E-15 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS13310 49d2d6fe1e132f57e483722e9db14643 320 PANTHER PTHR21621:SF2 135 315 6.5E-28 T 22-04-2016 HRM2_RS13310 49d2d6fe1e132f57e483722e9db14643 320 SUPERFAMILY SSF56059 137 314 9.02E-30 T 22-04-2016 HRM2_RS24845 f7b41c91039ce1c25e371ff32f61af77 180 PANTHER PTHR40547 19 99 7.2E-16 T 22-04-2016 HRM2_RS24845 f7b41c91039ce1c25e371ff32f61af77 180 Pfam PF09835 Uncharacterized protein conserved in bacteria (DUF2062) 17 172 1.9E-39 T 22-04-2016 IPR018639 Domain of unknown function DUF2062 HRM2_RS24845 f7b41c91039ce1c25e371ff32f61af77 180 PANTHER PTHR40547:SF1 19 99 7.2E-16 T 22-04-2016 HRM2_RS24200 b825f77bb9a174caaa32c371ba5e1be1 84 Gene3D G3DSA:1.10.260.40 14 78 8.5E-15 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS24200 b825f77bb9a174caaa32c371ba5e1be1 84 Pfam PF01381 Helix-turn-helix 20 71 9.4E-11 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS24200 b825f77bb9a174caaa32c371ba5e1be1 84 SUPERFAMILY SSF47413 14 75 1.83E-14 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS24200 b825f77bb9a174caaa32c371ba5e1be1 84 SMART SM00530 19 74 5.1E-10 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS21815 93268962ee7e6e07be334157dfcb87e0 137 SUPERFAMILY SSF160935 19 137 7.32E-26 T 22-04-2016 HRM2_RS21815 93268962ee7e6e07be334157dfcb87e0 137 Pfam PF06863 Protein of unknown function (DUF1254) 27 92 2.1E-10 T 22-04-2016 IPR010679 Domain of unknown function DUF1254 HRM2_RS00975 edbccad952e510b8d6aa626861982a4c 653 PANTHER PTHR30038 1 232 2.1E-163 T 22-04-2016 HRM2_RS00975 edbccad952e510b8d6aa626861982a4c 653 PANTHER PTHR30038 260 642 2.1E-163 T 22-04-2016 HRM2_RS00975 edbccad952e510b8d6aa626861982a4c 653 Gene3D G3DSA:1.10.569.10 270 459 1.7E-50 T 22-04-2016 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 HRM2_RS00975 edbccad952e510b8d6aa626861982a4c 653 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 7 207 1.9E-70 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS00975 edbccad952e510b8d6aa626861982a4c 653 Gene3D G3DSA:3.60.9.10 3 211 1.1E-76 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS00975 edbccad952e510b8d6aa626861982a4c 653 PANTHER PTHR30038:SF0 1 232 2.1E-163 T 22-04-2016 HRM2_RS00975 edbccad952e510b8d6aa626861982a4c 653 PANTHER PTHR30038:SF0 260 642 2.1E-163 T 22-04-2016 HRM2_RS00975 edbccad952e510b8d6aa626861982a4c 653 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 265 643 9.9E-90 T 22-04-2016 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS00975 edbccad952e510b8d6aa626861982a4c 653 SUPERFAMILY SSF56228 4 209 1.7E-65 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS00975 edbccad952e510b8d6aa626861982a4c 653 SMART SM00790 5 208 1.0E-92 T 22-04-2016 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS00975 edbccad952e510b8d6aa626861982a4c 653 SUPERFAMILY SSF48310 265 643 4.19E-77 T 22-04-2016 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 HRM2_RS01505 b5f1f84b29a81d22cbad8fb9ecafd062 601 SUPERFAMILY SSF56645 39 268 4.19E-46 T 22-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 HRM2_RS01505 b5f1f84b29a81d22cbad8fb9ecafd062 601 PANTHER PTHR10909 5 475 1.6E-138 T 22-04-2016 HRM2_RS01505 b5f1f84b29a81d22cbad8fb9ecafd062 601 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 268 2.1E-17 T 22-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 HRM2_RS01505 b5f1f84b29a81d22cbad8fb9ecafd062 601 Gene3D G3DSA:1.10.540.10 40 158 1.7E-14 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS01505 b5f1f84b29a81d22cbad8fb9ecafd062 601 Gene3D G3DSA:1.20.140.10 272 460 3.8E-45 T 22-04-2016 HRM2_RS01505 b5f1f84b29a81d22cbad8fb9ecafd062 601 PANTHER PTHR10909:SF269 5 475 1.6E-138 T 22-04-2016 HRM2_RS01505 b5f1f84b29a81d22cbad8fb9ecafd062 601 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 283 450 4.2E-17 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS01505 b5f1f84b29a81d22cbad8fb9ecafd062 601 SUPERFAMILY SSF47203 281 459 1.43E-40 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS01505 b5f1f84b29a81d22cbad8fb9ecafd062 601 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 466 593 8.8E-30 T 22-04-2016 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain HRM2_RS01505 b5f1f84b29a81d22cbad8fb9ecafd062 601 Gene3D G3DSA:2.40.110.10 160 268 3.0E-20 T 22-04-2016 HRM2_RS01505 b5f1f84b29a81d22cbad8fb9ecafd062 601 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 41 156 5.7E-9 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS15355 fb5a14f84e9eb44155cfd32d4c6ad967 278 PANTHER PTHR30024 8 213 3.5E-17 T 22-04-2016 HRM2_RS15355 fb5a14f84e9eb44155cfd32d4c6ad967 278 SUPERFAMILY SSF53850 4 213 4.92E-22 T 22-04-2016 HRM2_RS15355 fb5a14f84e9eb44155cfd32d4c6ad967 278 Gene3D G3DSA:3.40.190.10 86 210 8.1E-8 T 22-04-2016 HRM2_RS15355 fb5a14f84e9eb44155cfd32d4c6ad967 278 Pfam PF13379 NMT1-like family 30 213 1.7E-13 T 22-04-2016 HRM2_RS19950 86ab05b7c511c8d87fcd0f3349302ac3 517 Pfam PF13701 Transposase DDE domain group 1 19 507 3.8E-35 T 22-04-2016 IPR025668 Transposase DDE domain HRM2_RS15135 86ab05b7c511c8d87fcd0f3349302ac3 517 Pfam PF13701 Transposase DDE domain group 1 19 507 3.8E-35 T 22-04-2016 IPR025668 Transposase DDE domain HRM2_RS16905 86ab05b7c511c8d87fcd0f3349302ac3 517 Pfam PF13701 Transposase DDE domain group 1 19 507 3.8E-35 T 22-04-2016 IPR025668 Transposase DDE domain HRM2_RS20605 86ab05b7c511c8d87fcd0f3349302ac3 517 Pfam PF13701 Transposase DDE domain group 1 19 507 3.8E-35 T 22-04-2016 IPR025668 Transposase DDE domain HRM2_RS25140 6a5926d72d881cf8637e06be9168b7da 426 PANTHER PTHR30408 5 425 3.0E-54 T 22-04-2016 HRM2_RS25140 6a5926d72d881cf8637e06be9168b7da 426 Pfam PF01420 Type I restriction modification DNA specificity domain 16 198 2.6E-20 T 22-04-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 HRM2_RS25140 6a5926d72d881cf8637e06be9168b7da 426 Pfam PF01420 Type I restriction modification DNA specificity domain 228 403 5.8E-22 T 22-04-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 HRM2_RS25140 6a5926d72d881cf8637e06be9168b7da 426 SUPERFAMILY SSF116734 6 217 4.74E-52 T 22-04-2016 HRM2_RS25140 6a5926d72d881cf8637e06be9168b7da 426 PANTHER PTHR30408:SF2 5 425 3.0E-54 T 22-04-2016 HRM2_RS25140 6a5926d72d881cf8637e06be9168b7da 426 SUPERFAMILY SSF116734 217 425 6.05E-46 T 22-04-2016 HRM2_RS13480 39b1d303d90d8b8620cc151e8628b2d4 115 Pfam PF02699 Preprotein translocase subunit 24 97 4.2E-33 T 22-04-2016 IPR003849 Preprotein translocase YajC HRM2_RS13480 39b1d303d90d8b8620cc151e8628b2d4 115 PANTHER PTHR33909 1 94 1.1E-32 T 22-04-2016 HRM2_RS13480 39b1d303d90d8b8620cc151e8628b2d4 115 SMART SM01323 19 101 6.1E-48 T 22-04-2016 IPR003849 Preprotein translocase YajC HRM2_RS13480 39b1d303d90d8b8620cc151e8628b2d4 115 PRINTS PR01853 Bacterial YajC preprotein translocase signature 41 59 1.2E-16 T 22-04-2016 IPR003849 Preprotein translocase YajC HRM2_RS13480 39b1d303d90d8b8620cc151e8628b2d4 115 PRINTS PR01853 Bacterial YajC preprotein translocase signature 21 41 1.2E-16 T 22-04-2016 IPR003849 Preprotein translocase YajC HRM2_RS13480 39b1d303d90d8b8620cc151e8628b2d4 115 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 21 98 3.5E-32 T 22-04-2016 IPR003849 Preprotein translocase YajC HRM2_RS13480 39b1d303d90d8b8620cc151e8628b2d4 115 PANTHER PTHR33909:SF1 1 94 1.1E-32 T 22-04-2016 HRM2_RS15375 4ff09975700915aaf1fc8ed14e371e7b 574 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 3 158 2.1E-23 T 22-04-2016 IPR008040 Hydantoinaseoxoprolinase, N-terminal HRM2_RS15375 4ff09975700915aaf1fc8ed14e371e7b 574 Pfam PF01968 Hydantoinase/oxoprolinase 178 458 9.0E-43 T 22-04-2016 IPR002821 Hydantoinase/oxoprolinase GO:0016787 HRM2_RS15375 4ff09975700915aaf1fc8ed14e371e7b 574 SUPERFAMILY SSF53067 253 338 7.32E-13 T 22-04-2016 HRM2_RS15375 4ff09975700915aaf1fc8ed14e371e7b 574 SUPERFAMILY SSF53067 382 455 7.32E-13 T 22-04-2016 HRM2_RS15375 4ff09975700915aaf1fc8ed14e371e7b 574 Gene3D G3DSA:3.30.420.190 252 287 2.4E-4 T 22-04-2016 HRM2_RS15375 4ff09975700915aaf1fc8ed14e371e7b 574 PANTHER PTHR11365 1 519 5.3E-64 T 22-04-2016 HRM2_RS07290 a5432914aa712d9e44a92b1b24fc7042 137 SUPERFAMILY SSF52206 36 133 2.48E-21 T 22-04-2016 IPR015032 MTH538 TIR-like domain HRM2_RS07290 a5432914aa712d9e44a92b1b24fc7042 137 Pfam PF08937 MTH538 TIR-like domain (DUF1863) 5 119 2.4E-15 T 22-04-2016 IPR015032 MTH538 TIR-like domain HRM2_RS07290 a5432914aa712d9e44a92b1b24fc7042 137 Gene3D G3DSA:3.40.50.9200 2 134 9.8E-37 T 22-04-2016 IPR015032 MTH538 TIR-like domain HRM2_RS05205 39d115d557fdb4942c6eeab1e6ecc5a8 850 Pfam PF03522 Solute carrier family 12 611 686 2.0E-8 T 22-04-2016 IPR018491 SLC12A transporter, C-terminal GO:0005215|GO:0006811|GO:0016020 Reactome: REACT_15518 HRM2_RS05205 39d115d557fdb4942c6eeab1e6ecc5a8 850 Pfam PF00324 Amino acid permease 23 436 4.6E-61 T 22-04-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 HRM2_RS05205 39d115d557fdb4942c6eeab1e6ecc5a8 850 PANTHER PTHR11827 10 698 1.2E-164 T 22-04-2016 HRM2_RS04310 812564cf42315f63875e2defc6952ee3 167 Pfam PF01872 RibD C-terminal domain 2 154 6.8E-19 T 22-04-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 HRM2_RS04310 812564cf42315f63875e2defc6952ee3 167 Gene3D G3DSA:3.40.430.10 1 167 8.0E-42 T 22-04-2016 IPR024072 Dihydrofolate reductase-like domain HRM2_RS04310 812564cf42315f63875e2defc6952ee3 167 SUPERFAMILY SSF53597 1 164 7.85E-39 T 22-04-2016 IPR024072 Dihydrofolate reductase-like domain HRM2_RS09865 9809faf4b529da8c76b4f13ef336bb64 189 SUPERFAMILY SSF55729 37 174 1.42E-10 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS09865 9809faf4b529da8c76b4f13ef336bb64 189 Gene3D G3DSA:3.40.630.30 36 173 3.2E-9 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS09865 9809faf4b529da8c76b4f13ef336bb64 189 Pfam PF00583 Acetyltransferase (GNAT) family 119 169 4.9E-6 T 22-04-2016 IPR000182 GNAT domain GO:0008080 HRM2_RS01265 5e3d71b79a64deb97f67743af1210a8f 228 SUPERFAMILY SSF63848 111 213 2.22E-26 T 22-04-2016 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 HRM2_RS01265 5e3d71b79a64deb97f67743af1210a8f 228 Gene3D G3DSA:2.160.20.70 108 213 9.4E-30 T 22-04-2016 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 HRM2_RS01265 5e3d71b79a64deb97f67743af1210a8f 228 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 8 214 15.513 T 22-04-2016 IPR013033 Septum formation inhibitor MinC GO:0000917|GO:0051726 HRM2_RS01265 5e3d71b79a64deb97f67743af1210a8f 228 PANTHER PTHR34108 80 226 4.0E-29 T 22-04-2016 HRM2_RS01265 5e3d71b79a64deb97f67743af1210a8f 228 PANTHER PTHR34108:SF1 80 226 4.0E-29 T 22-04-2016 HRM2_RS01265 5e3d71b79a64deb97f67743af1210a8f 228 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 114 207 1.8E-27 T 22-04-2016 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 HRM2_RS06700 b5827801182ffa170ffb6781c3769930 251 SUPERFAMILY SSF159713 10 244 1.57E-56 T 22-04-2016 HRM2_RS06700 b5827801182ffa170ffb6781c3769930 251 Pfam PF04016 Putative heavy-metal chelation 109 241 3.2E-35 T 22-04-2016 IPR007161 Putative heavy-metal chelation domain HRM2_RS06700 b5827801182ffa170ffb6781c3769930 251 Pfam PF13938 Putative heavy-metal chelation 20 96 6.3E-10 T 22-04-2016 IPR025251 Domain of unknown function DUF4213 HRM2_RS14475 b35cc429863bbc688a0b32d14522a8a5 249 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 238 8.3E-43 T 22-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 HRM2_RS14475 b35cc429863bbc688a0b32d14522a8a5 249 PANTHER PTHR11941 1 243 1.5E-56 T 22-04-2016 HRM2_RS14475 b35cc429863bbc688a0b32d14522a8a5 249 Gene3D G3DSA:3.90.226.10 1 242 6.3E-62 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS14475 b35cc429863bbc688a0b32d14522a8a5 249 SUPERFAMILY SSF52096 1 244 6.45E-63 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS17075 f5c6135ea66054bf17fa84e9e27a7535 230 PANTHER PTHR11922 42 188 5.4E-58 T 22-04-2016 HRM2_RS17075 f5c6135ea66054bf17fa84e9e27a7535 230 SUPERFAMILY SSF52317 1 216 2.29E-54 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS17075 f5c6135ea66054bf17fa84e9e27a7535 230 PANTHER PTHR11922:SF45 42 188 5.4E-58 T 22-04-2016 HRM2_RS17075 f5c6135ea66054bf17fa84e9e27a7535 230 Gene3D G3DSA:3.40.50.880 1 227 4.6E-59 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS17075 f5c6135ea66054bf17fa84e9e27a7535 230 Pfam PF00117 Glutamine amidotransferase class-I 21 180 7.4E-18 T 22-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 HRM2_RS06910 c00346c0a51f052eaf479e163607bb25 260 PANTHER PTHR10859:SF92 18 199 1.4E-23 T 22-04-2016 HRM2_RS06910 c00346c0a51f052eaf479e163607bb25 260 Pfam PF00535 Glycosyl transferase family 2 19 133 1.4E-17 T 22-04-2016 IPR001173 Glycosyltransferase 2-like HRM2_RS06910 c00346c0a51f052eaf479e163607bb25 260 Gene3D G3DSA:3.90.550.10 18 221 3.3E-24 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS06910 c00346c0a51f052eaf479e163607bb25 260 SUPERFAMILY SSF53448 17 225 7.51E-34 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS06910 c00346c0a51f052eaf479e163607bb25 260 PANTHER PTHR10859 18 199 1.4E-23 T 22-04-2016 HRM2_RS21010 9fe723ebed9376a0820c5f9e6765a088 125 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 7 118 1.1E-19 T 22-04-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 HRM2_RS21010 9fe723ebed9376a0820c5f9e6765a088 125 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 5 123 18.04 T 22-04-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 HRM2_RS21010 9fe723ebed9376a0820c5f9e6765a088 125 PANTHER PTHR28259 6 123 5.2E-26 T 22-04-2016 HRM2_RS15985 b27eeae4d6c217c71ec8828789bb2d14 333 TIGRFAM TIGR00749 glk: glucokinase 11 325 1.9E-86 T 22-04-2016 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 HRM2_RS15985 b27eeae4d6c217c71ec8828789bb2d14 333 PANTHER PTHR30514 4 332 8.4E-78 T 22-04-2016 HRM2_RS15985 b27eeae4d6c217c71ec8828789bb2d14 333 Gene3D G3DSA:3.40.367.20 106 314 2.5E-67 T 22-04-2016 HRM2_RS15985 b27eeae4d6c217c71ec8828789bb2d14 333 Pfam PF02685 Glucokinase 11 330 8.1E-100 T 22-04-2016 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 HRM2_RS15985 b27eeae4d6c217c71ec8828789bb2d14 333 SUPERFAMILY SSF53067 10 330 1.47E-58 T 22-04-2016 HRM2_RS15985 b27eeae4d6c217c71ec8828789bb2d14 333 PANTHER PTHR30514:SF0 4 332 8.4E-78 T 22-04-2016 HRM2_RS20655 c67d01ddf292d1aa5c64fc6ad1db5901 147 Gene3D G3DSA:3.40.190.10 30 143 3.4E-8 T 22-04-2016 HRM2_RS20655 c67d01ddf292d1aa5c64fc6ad1db5901 147 SUPERFAMILY SSF53850 27 142 5.43E-12 T 22-04-2016 HRM2_RS07695 d8cd76923e239586a5524a5dbbaff472 65 SUPERFAMILY SSF55347 4 46 5.02E-6 T 22-04-2016 HRM2_RS07695 d8cd76923e239586a5524a5dbbaff472 65 PANTHER PTHR10836:SF50 2 65 8.8E-14 T 22-04-2016 HRM2_RS07695 d8cd76923e239586a5524a5dbbaff472 65 PANTHER PTHR10836 2 65 8.8E-14 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS07695 d8cd76923e239586a5524a5dbbaff472 65 Gene3D G3DSA:3.30.360.10 4 50 3.4E-7 T 22-04-2016 HRM2_RS07695 d8cd76923e239586a5524a5dbbaff472 65 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 3 41 9.9E-6 T 22-04-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: REACT_474 HRM2_RS18680 d013bd0e4c9b2625b6516baae10aa7bb 300 PANTHER PTHR16222 5 299 2.8E-33 T 22-04-2016 HRM2_RS18680 d013bd0e4c9b2625b6516baae10aa7bb 300 Pfam PF03747 ADP-ribosylglycohydrolase 8 283 4.8E-57 T 22-04-2016 IPR005502 ADP-ribosylation/Crystallin J1 HRM2_RS18680 d013bd0e4c9b2625b6516baae10aa7bb 300 SUPERFAMILY SSF101478 4 299 2.09E-51 T 22-04-2016 IPR005502 ADP-ribosylation/Crystallin J1 HRM2_RS05615 21f7f206bf21964d7612d640228b9b4a 255 PRINTS PR00813 Bacterial general secretion pathway protein G signature 73 91 5.9E-5 T 22-04-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 HRM2_RS05615 21f7f206bf21964d7612d640228b9b4a 255 PRINTS PR00813 Bacterial general secretion pathway protein G signature 36 61 5.9E-5 T 22-04-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 HRM2_RS05615 21f7f206bf21964d7612d640228b9b4a 255 Pfam PF13633 Prokaryotic N-terminal methylation site 35 57 2.7E-6 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site HRM2_RS05615 21f7f206bf21964d7612d640228b9b4a 255 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 35 54 4.4E-6 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site HRM2_RS05615 21f7f206bf21964d7612d640228b9b4a 255 SUPERFAMILY SSF54523 73 238 2.12E-9 T 22-04-2016 HRM2_RS18930 4332b7e79e2488d7fcab671e6e7c94ce 168 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 27 158 1.7E-26 T 22-04-2016 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component HRM2_RS18930 4332b7e79e2488d7fcab671e6e7c94ce 168 PANTHER PTHR35011 1 167 4.1E-19 T 22-04-2016 HRM2_RS14090 41996d8d7e15fbec50ccd9a161f94d14 281 PANTHER PTHR30570 39 280 4.1E-56 T 22-04-2016 HRM2_RS14090 41996d8d7e15fbec50ccd9a161f94d14 281 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 3 280 2.2E-62 T 22-04-2016 IPR011862 Phosphate binding protein GO:0006810 HRM2_RS14090 41996d8d7e15fbec50ccd9a161f94d14 281 Gene3D G3DSA:3.40.190.10 63 119 2.3E-5 T 22-04-2016 HRM2_RS14090 41996d8d7e15fbec50ccd9a161f94d14 281 Gene3D G3DSA:3.40.190.10 240 281 2.3E-5 T 22-04-2016 HRM2_RS14090 41996d8d7e15fbec50ccd9a161f94d14 281 Gene3D G3DSA:3.40.190.10 120 239 1.2E-42 T 22-04-2016 HRM2_RS14090 41996d8d7e15fbec50ccd9a161f94d14 281 Pfam PF12849 PBP superfamily domain 39 267 7.4E-32 T 22-04-2016 IPR024370 PBP domain HRM2_RS14090 41996d8d7e15fbec50ccd9a161f94d14 281 PANTHER PTHR30570:SF1 39 280 4.1E-56 T 22-04-2016 HRM2_RS14090 41996d8d7e15fbec50ccd9a161f94d14 281 SUPERFAMILY SSF53850 39 281 1.35E-69 T 22-04-2016 HRM2_RS22375 0a2f07b11300679a14bf7fc33a794028 247 SMART SM00862 163 239 1.5E-28 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HRM2_RS22375 0a2f07b11300679a14bf7fc33a794028 247 PANTHER PTHR26402:SF292 11 244 1.8E-89 T 22-04-2016 HRM2_RS22375 0a2f07b11300679a14bf7fc33a794028 247 Pfam PF00486 Transcriptional regulatory protein, C terminal 163 239 3.4E-26 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HRM2_RS22375 0a2f07b11300679a14bf7fc33a794028 247 SUPERFAMILY SSF46894 139 240 1.02E-30 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HRM2_RS22375 0a2f07b11300679a14bf7fc33a794028 247 Gene3D G3DSA:1.10.10.10 147 241 1.4E-34 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS22375 0a2f07b11300679a14bf7fc33a794028 247 Gene3D G3DSA:3.40.50.2300 9 146 2.7E-42 T 22-04-2016 HRM2_RS22375 0a2f07b11300679a14bf7fc33a794028 247 Pfam PF00072 Response regulator receiver domain 13 121 3.1E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS22375 0a2f07b11300679a14bf7fc33a794028 247 SMART SM00448 11 121 9.8E-42 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS22375 0a2f07b11300679a14bf7fc33a794028 247 PANTHER PTHR26402 11 244 1.8E-89 T 22-04-2016 HRM2_RS22375 0a2f07b11300679a14bf7fc33a794028 247 SUPERFAMILY SSF52172 8 135 6.69E-42 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS07340 5037f167f19596ddad03a910864eabaa 547 SUPERFAMILY SSF52540 1 110 1.03E-11 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07340 5037f167f19596ddad03a910864eabaa 547 SUPERFAMILY SSF52540 403 486 1.03E-11 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07340 5037f167f19596ddad03a910864eabaa 547 Pfam PF13175 AAA ATPase domain 1 45 2.3E-11 T 22-04-2016 HRM2_RS07340 5037f167f19596ddad03a910864eabaa 547 Pfam PF13175 AAA ATPase domain 389 477 6.7E-11 T 22-04-2016 HRM2_RS07340 5037f167f19596ddad03a910864eabaa 547 Gene3D G3DSA:3.40.50.300 120 202 5.3E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07340 5037f167f19596ddad03a910864eabaa 547 Gene3D G3DSA:3.40.50.300 1 79 5.3E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07340 5037f167f19596ddad03a910864eabaa 547 Gene3D G3DSA:3.40.50.300 337 490 5.3E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS20080 25af70e97b83b6d490fa66540008d443 438 PANTHER PTHR30365:SF0 1 438 2.6E-223 T 22-04-2016 HRM2_RS20080 25af70e97b83b6d490fa66540008d443 438 PANTHER PTHR30365 1 438 2.6E-223 T 22-04-2016 HRM2_RS20080 25af70e97b83b6d490fa66540008d443 438 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 431 3.2E-175 T 22-04-2016 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 HRM2_RS20080 25af70e97b83b6d490fa66540008d443 438 PIRSF PIRSF006446 1 438 1.1E-173 T 22-04-2016 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 HRM2_RS14590 c7f1921f9e9111418d47e1dbaa5a0594 292 Pfam PF01882 Protein of unknown function DUF58 37 122 7.2E-23 T 22-04-2016 IPR002881 Domain of unknown function DUF58 HRM2_RS14590 c7f1921f9e9111418d47e1dbaa5a0594 292 SUPERFAMILY SSF53300 73 215 1.93E-14 T 22-04-2016 IPR002035 von Willebrand factor, type A HRM2_RS14590 c7f1921f9e9111418d47e1dbaa5a0594 292 Gene3D G3DSA:3.40.50.410 79 172 2.0E-4 T 22-04-2016 IPR002035 von Willebrand factor, type A HRM2_RS14590 c7f1921f9e9111418d47e1dbaa5a0594 292 PANTHER PTHR33608 1 292 6.2E-63 T 22-04-2016 HRM2_RS14590 c7f1921f9e9111418d47e1dbaa5a0594 292 PANTHER PTHR33608:SF5 1 292 6.2E-63 T 22-04-2016 HRM2_RS25390 863327f321b6168d834563f7ab0f1a80 165 SUPERFAMILY SSF51206 5 145 7.46E-21 T 22-04-2016 IPR018490 Cyclic nucleotide-binding-like HRM2_RS25390 863327f321b6168d834563f7ab0f1a80 165 Pfam PF00027 Cyclic nucleotide-binding domain 31 126 2.2E-8 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain HRM2_RS25390 863327f321b6168d834563f7ab0f1a80 165 SMART SM00100 12 142 5.1E-5 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain HRM2_RS25390 863327f321b6168d834563f7ab0f1a80 165 Gene3D G3DSA:2.60.120.10 5 148 1.5E-16 T 22-04-2016 IPR014710 RmlC-like jelly roll fold HRM2_RS07605 8b6c6a501c137edc60ced30dd7c812cf 390 SUPERFAMILY SSF55347 126 327 3.47E-39 T 22-04-2016 HRM2_RS07605 8b6c6a501c137edc60ced30dd7c812cf 390 SUPERFAMILY SSF51735 1 172 1.62E-17 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS07605 8b6c6a501c137edc60ced30dd7c812cf 390 Gene3D G3DSA:3.40.50.720 1 139 1.3E-7 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS07605 8b6c6a501c137edc60ced30dd7c812cf 390 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 125 380 1.6E-50 T 22-04-2016 IPR032095 Saccharopine dehydrogenase, C-terminal HRM2_RS07605 8b6c6a501c137edc60ced30dd7c812cf 390 Gene3D G3DSA:3.30.360.10 292 338 2.2E-32 T 22-04-2016 HRM2_RS07605 8b6c6a501c137edc60ced30dd7c812cf 390 Gene3D G3DSA:3.30.360.10 140 249 2.2E-32 T 22-04-2016 HRM2_RS07605 8b6c6a501c137edc60ced30dd7c812cf 390 PANTHER PTHR11133:SF14 1 389 3.3E-56 T 22-04-2016 HRM2_RS07605 8b6c6a501c137edc60ced30dd7c812cf 390 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 3 121 3.3E-15 T 22-04-2016 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 HRM2_RS07605 8b6c6a501c137edc60ced30dd7c812cf 390 PANTHER PTHR11133 1 389 3.3E-56 T 22-04-2016 HRM2_RS10410 ff1c16f35ec7a72e04803d2200ed4b90 211 SUPERFAMILY SSF47473 41 153 7.47E-12 T 22-04-2016 IPR011992 EF-hand domain pair HRM2_RS10410 ff1c16f35ec7a72e04803d2200ed4b90 211 ProSitePatterns PS00018 EF-hand calcium-binding domain. 64 76 - T 22-04-2016 IPR018247 EF-Hand 1, calcium-binding site HRM2_RS10410 ff1c16f35ec7a72e04803d2200ed4b90 211 ProSitePatterns PS00018 EF-hand calcium-binding domain. 138 150 - T 22-04-2016 IPR018247 EF-Hand 1, calcium-binding site HRM2_RS10410 ff1c16f35ec7a72e04803d2200ed4b90 211 SMART SM00054 129 157 5.2 T 22-04-2016 IPR002048 EF-hand domain GO:0005509 HRM2_RS10410 ff1c16f35ec7a72e04803d2200ed4b90 211 SMART SM00054 55 83 3.6 T 22-04-2016 IPR002048 EF-hand domain GO:0005509 HRM2_RS10410 ff1c16f35ec7a72e04803d2200ed4b90 211 Pfam PF13202 EF hand 133 151 0.002 T 22-04-2016 IPR002048 EF-hand domain GO:0005509 HRM2_RS10410 ff1c16f35ec7a72e04803d2200ed4b90 211 Pfam PF13202 EF hand 59 79 0.026 T 22-04-2016 IPR002048 EF-hand domain GO:0005509 HRM2_RS10410 ff1c16f35ec7a72e04803d2200ed4b90 211 Gene3D G3DSA:1.10.238.10 58 143 1.0E-9 T 22-04-2016 IPR011992 EF-hand domain pair HRM2_RS10410 ff1c16f35ec7a72e04803d2200ed4b90 211 Gene3D G3DSA:1.10.238.10 144 185 3.8E-5 T 22-04-2016 IPR011992 EF-hand domain pair HRM2_RS05160 a0b2c0e967d582921965875ed1f64381 252 SUPERFAMILY SSF48317 21 238 1.01E-11 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase HRM2_RS05160 a0b2c0e967d582921965875ed1f64381 252 Gene3D G3DSA:1.20.144.10 75 234 4.3E-4 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase HRM2_RS19070 50006dd32325bbfa7bb13ccde63644fa 371 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 19 365 2.0E-152 T 22-04-2016 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 HRM2_RS19070 50006dd32325bbfa7bb13ccde63644fa 371 PIRSF PIRSF015658 1 371 1.9E-165 T 22-04-2016 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 HRM2_RS19070 50006dd32325bbfa7bb13ccde63644fa 371 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 20 369 7.4E-155 T 22-04-2016 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 HRM2_RS19070 50006dd32325bbfa7bb13ccde63644fa 371 PANTHER PTHR35806 1 371 1.4E-173 T 22-04-2016 HRM2_RS19005 50006dd32325bbfa7bb13ccde63644fa 371 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 19 365 2.0E-152 T 22-04-2016 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 HRM2_RS19005 50006dd32325bbfa7bb13ccde63644fa 371 PIRSF PIRSF015658 1 371 1.9E-165 T 22-04-2016 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 HRM2_RS19005 50006dd32325bbfa7bb13ccde63644fa 371 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 20 369 7.4E-155 T 22-04-2016 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 HRM2_RS19005 50006dd32325bbfa7bb13ccde63644fa 371 PANTHER PTHR35806 1 371 1.4E-173 T 22-04-2016 HRM2_RS08575 d9e1df8999943890349f2db6425b8efd 760 SUPERFAMILY SSF53955 54 253 4.5E-46 T 22-04-2016 IPR023346 Lysozyme-like domain HRM2_RS08575 d9e1df8999943890349f2db6425b8efd 760 PANTHER PTHR32282:SF0 1 707 4.4E-108 T 22-04-2016 HRM2_RS08575 d9e1df8999943890349f2db6425b8efd 760 Gene3D G3DSA:1.10.3810.10 64 240 4.5E-40 T 22-04-2016 HRM2_RS08575 d9e1df8999943890349f2db6425b8efd 760 Pfam PF00905 Penicillin binding protein transpeptidase domain 334 568 3.7E-15 T 22-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 HRM2_RS08575 d9e1df8999943890349f2db6425b8efd 760 Pfam PF06832 Penicillin-Binding Protein C-terminus Family 670 740 1.3E-6 T 22-04-2016 IPR009647 Penicillin-binding, C-terminal KEGG: 00230+2.4.2.-|KEGG: 00514+2.4.2.-|UniPathway: UPA00219 HRM2_RS08575 d9e1df8999943890349f2db6425b8efd 760 Pfam PF00912 Transglycosylase 67 219 1.5E-40 T 22-04-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 HRM2_RS08575 d9e1df8999943890349f2db6425b8efd 760 Gene3D G3DSA:3.40.710.10 302 645 4.2E-72 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HRM2_RS08575 d9e1df8999943890349f2db6425b8efd 760 PANTHER PTHR32282 1 707 4.4E-108 T 22-04-2016 HRM2_RS08575 d9e1df8999943890349f2db6425b8efd 760 SUPERFAMILY SSF56601 302 643 1.01E-75 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HRM2_RS02395 62fd44a4253542733afe7925662f57bf 696 Pfam PF03477 ATP cone domain 5 92 1.3E-19 T 22-04-2016 IPR005144 ATP-cone domain HRM2_RS02395 62fd44a4253542733afe7925662f57bf 696 PANTHER PTHR21075 1 696 1.8E-228 T 22-04-2016 HRM2_RS02395 62fd44a4253542733afe7925662f57bf 696 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 119 693 2.8E-192 T 22-04-2016 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 HRM2_RS02395 62fd44a4253542733afe7925662f57bf 696 SUPERFAMILY SSF51998 120 677 3.36E-163 T 22-04-2016 HRM2_RS02395 62fd44a4253542733afe7925662f57bf 696 Gene3D G3DSA:3.20.70.20 124 676 4.3E-213 T 22-04-2016 HRM2_RS02395 62fd44a4253542733afe7925662f57bf 696 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 118 692 7.8E-170 T 22-04-2016 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 HRM2_RS07935 af9d29ff9243ffb4d862362084f310bc 507 Gene3D G3DSA:3.40.1080.10 21 230 2.6E-40 T 22-04-2016 HRM2_RS07935 af9d29ff9243ffb4d862362084f310bc 507 Gene3D G3DSA:3.40.810.20 237 501 5.4E-69 T 22-04-2016 HRM2_RS07935 af9d29ff9243ffb4d862362084f310bc 507 PANTHER PTHR21432:SF10 1 507 1.1E-223 T 22-04-2016 HRM2_RS07935 af9d29ff9243ffb4d862362084f310bc 507 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 22 505 1.9E-202 T 22-04-2016 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 HRM2_RS07935 af9d29ff9243ffb4d862362084f310bc 507 PANTHER PTHR21432 1 507 1.1E-223 T 22-04-2016 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 HRM2_RS07935 af9d29ff9243ffb4d862362084f310bc 507 SUPERFAMILY SSF100950 13 231 6.28E-59 T 22-04-2016 HRM2_RS07935 af9d29ff9243ffb4d862362084f310bc 507 SUPERFAMILY SSF100950 236 506 2.93E-69 T 22-04-2016 HRM2_RS07935 af9d29ff9243ffb4d862362084f310bc 507 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 18 225 6.8E-27 T 22-04-2016 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 HRM2_RS07935 af9d29ff9243ffb4d862362084f310bc 507 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 330 473 4.1E-42 T 22-04-2016 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain HRM2_RS22670 aab6e738eb4c6c52c28aa4f0682d1b7a 336 PIRSF PIRSF004869 1 313 4.7E-98 T 22-04-2016 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted HRM2_RS22670 aab6e738eb4c6c52c28aa4f0682d1b7a 336 SMART SM00729 71 278 5.8E-4 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS22670 aab6e738eb4c6c52c28aa4f0682d1b7a 336 PANTHER PTHR30352:SF5 1 336 3.7E-148 T 22-04-2016 HRM2_RS22670 aab6e738eb4c6c52c28aa4f0682d1b7a 336 Gene3D G3DSA:3.80.30.10 123 286 3.9E-34 T 22-04-2016 HRM2_RS22670 aab6e738eb4c6c52c28aa4f0682d1b7a 336 PANTHER PTHR30352 1 336 3.7E-148 T 22-04-2016 HRM2_RS22670 aab6e738eb4c6c52c28aa4f0682d1b7a 336 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 6 336 6.2E-101 T 22-04-2016 IPR027596 AmmeMemoRadiSam system radical SAM enzyme HRM2_RS22670 aab6e738eb4c6c52c28aa4f0682d1b7a 336 Pfam PF04055 Radical SAM superfamily 76 231 3.6E-22 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS22670 aab6e738eb4c6c52c28aa4f0682d1b7a 336 SUPERFAMILY SSF102114 56 313 1.28E-30 T 22-04-2016 HRM2_RS22465 c305fa01abbb53cc4fae1f8282e459e1 210 Pfam PF11172 Protein of unknown function (DUF2959) 10 207 1.2E-88 T 22-04-2016 IPR021342 Protein of unknown function DUF2959 HRM2_RS22465 c305fa01abbb53cc4fae1f8282e459e1 210 SUPERFAMILY SSF75708 52 193 4.45E-6 T 22-04-2016 HRM2_RS08495 dfb6d1b3854b257630fb202e351722b5 354 Pfam PF00472 RF-1 domain 209 318 2.1E-39 T 22-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 HRM2_RS08495 dfb6d1b3854b257630fb202e351722b5 354 Pfam PF03462 PCRF domain 8 201 2.8E-70 T 22-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 HRM2_RS08495 dfb6d1b3854b257630fb202e351722b5 354 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 352 2.7E-157 T 22-04-2016 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 HRM2_RS08495 dfb6d1b3854b257630fb202e351722b5 354 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 354 39.263 T 22-04-2016 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 HRM2_RS08495 dfb6d1b3854b257630fb202e351722b5 354 SMART SM00937 63 176 8.6E-56 T 22-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 HRM2_RS08495 dfb6d1b3854b257630fb202e351722b5 354 Gene3D G3DSA:3.30.160.20 208 286 3.2E-32 T 22-04-2016 IPR014720 Double-stranded RNA-binding domain HRM2_RS08495 dfb6d1b3854b257630fb202e351722b5 354 PANTHER PTHR11075 1 353 5.0E-172 T 22-04-2016 HRM2_RS08495 dfb6d1b3854b257630fb202e351722b5 354 SUPERFAMILY SSF75620 8 350 1.7E-130 T 22-04-2016 HRM2_RS08495 dfb6d1b3854b257630fb202e351722b5 354 PANTHER PTHR11075:SF9 1 353 5.0E-172 T 22-04-2016 HRM2_RS08495 dfb6d1b3854b257630fb202e351722b5 354 Gene3D G3DSA:1.20.58.410 4 91 3.4E-20 T 22-04-2016 HRM2_RS08495 dfb6d1b3854b257630fb202e351722b5 354 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 225 241 - T 22-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 HRM2_RS18220 2fbf0ab429030895239e06c16068e421 142 Gene3D G3DSA:2.30.290.10 1 141 5.2E-42 T 22-04-2016 IPR024046 Flagellar assembly factor FliW domain HRM2_RS18220 2fbf0ab429030895239e06c16068e421 142 Hamap MF_01185 Flagellar assembly factor FliW [fliW]. 18 142 20.445 T 22-04-2016 IPR003775 Flagellar assembly factor FliW GO:0044780 HRM2_RS18220 2fbf0ab429030895239e06c16068e421 142 PANTHER PTHR39190 3 140 8.7E-34 T 22-04-2016 HRM2_RS18220 2fbf0ab429030895239e06c16068e421 142 Pfam PF02623 FliW protein 22 139 1.7E-32 T 22-04-2016 IPR003775 Flagellar assembly factor FliW GO:0044780 HRM2_RS18220 2fbf0ab429030895239e06c16068e421 142 SUPERFAMILY SSF141457 2 141 1.96E-35 T 22-04-2016 IPR024046 Flagellar assembly factor FliW domain HRM2_RS11700 b298ccc7bc85ec9383d25a232ac4db88 76 Pfam PF02597 ThiS family 6 76 3.5E-12 T 22-04-2016 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 HRM2_RS11700 b298ccc7bc85ec9383d25a232ac4db88 76 SUPERFAMILY SSF54285 1 74 1.1E-13 T 22-04-2016 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp HRM2_RS11700 b298ccc7bc85ec9383d25a232ac4db88 76 Gene3D G3DSA:3.10.20.30 2 76 1.8E-17 T 22-04-2016 IPR012675 Beta-grasp domain HRM2_RS11335 3b52f8a5025aff4522de13dead68aca7 534 Gene3D G3DSA:3.40.50.300 347 524 9.8E-22 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11335 3b52f8a5025aff4522de13dead68aca7 534 Pfam PF13671 AAA domain 351 498 1.1E-23 T 22-04-2016 HRM2_RS11335 3b52f8a5025aff4522de13dead68aca7 534 PANTHER PTHR12083:SF8 12 383 5.2E-121 T 22-04-2016 HRM2_RS11335 3b52f8a5025aff4522de13dead68aca7 534 PANTHER PTHR12083:SF8 412 513 5.2E-121 T 22-04-2016 HRM2_RS11335 3b52f8a5025aff4522de13dead68aca7 534 Gene3D G3DSA:3.90.1200.10 179 317 2.3E-6 T 22-04-2016 HRM2_RS11335 3b52f8a5025aff4522de13dead68aca7 534 PANTHER PTHR12083 12 383 5.2E-121 T 22-04-2016 HRM2_RS11335 3b52f8a5025aff4522de13dead68aca7 534 PANTHER PTHR12083 412 513 5.2E-121 T 22-04-2016 HRM2_RS11335 3b52f8a5025aff4522de13dead68aca7 534 SUPERFAMILY SSF56112 16 304 3.4E-15 T 22-04-2016 IPR011009 Protein kinase-like domain HRM2_RS11335 3b52f8a5025aff4522de13dead68aca7 534 SUPERFAMILY SSF52540 348 524 2.24E-20 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS00815 1856f4f4df50d286cf189baaf1acd69c 252 PIRSF PIRSF004846 2 251 7.1E-56 T 22-04-2016 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 HRM2_RS00815 1856f4f4df50d286cf189baaf1acd69c 252 Gene3D G3DSA:3.40.190.10 22 90 2.2E-5 T 22-04-2016 HRM2_RS00815 1856f4f4df50d286cf189baaf1acd69c 252 Gene3D G3DSA:3.40.190.10 102 246 1.1E-27 T 22-04-2016 HRM2_RS00815 1856f4f4df50d286cf189baaf1acd69c 252 PANTHER PTHR30632 20 249 3.2E-45 T 22-04-2016 HRM2_RS00815 1856f4f4df50d286cf189baaf1acd69c 252 SUPERFAMILY SSF53850 22 249 1.19E-55 T 22-04-2016 HRM2_RS00815 1856f4f4df50d286cf189baaf1acd69c 252 PANTHER PTHR30632:SF0 20 249 3.2E-45 T 22-04-2016 HRM2_RS00815 1856f4f4df50d286cf189baaf1acd69c 252 Pfam PF13531 Bacterial extracellular solute-binding protein 24 247 4.2E-51 T 22-04-2016 HRM2_RS00815 1856f4f4df50d286cf189baaf1acd69c 252 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 31 246 8.7E-27 T 22-04-2016 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 HRM2_RS11920 ead7f0236c2f40a2c7884fa637023367 240 PIRSF PIRSF006421 9 240 8.0E-60 T 22-04-2016 IPR007183 Uncharacterised protein family UPF0280 HRM2_RS11920 ead7f0236c2f40a2c7884fa637023367 240 Gene3D G3DSA:3.10.520.10 3 238 4.3E-82 T 22-04-2016 IPR007183 Uncharacterised protein family UPF0280 HRM2_RS11920 ead7f0236c2f40a2c7884fa637023367 240 SUPERFAMILY SSF143631 3 238 1.96E-75 T 22-04-2016 IPR003374 ApbE-like domain HRM2_RS05875 377c6e88a0e947cab58bbac49816dfe1 270 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 210 221 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS05875 377c6e88a0e947cab58bbac49816dfe1 270 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 160 171 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS05875 377c6e88a0e947cab58bbac49816dfe1 270 SUPERFAMILY SSF46548 148 238 5.49E-14 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS05875 377c6e88a0e947cab58bbac49816dfe1 270 Gene3D G3DSA:1.10.1060.10 152 237 9.8E-10 T 22-04-2016 HRM2_RS10335 cf87a220a46ea65ab076973d3a92e767 250 PANTHER PTHR30027 1 248 1.7E-84 T 22-04-2016 HRM2_RS10335 cf87a220a46ea65ab076973d3a92e767 250 SUPERFAMILY SSF75217 73 245 9.59E-51 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases HRM2_RS10335 cf87a220a46ea65ab076973d3a92e767 250 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 1 245 8.3E-61 T 22-04-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HRM2_RS10335 cf87a220a46ea65ab076973d3a92e767 250 PANTHER PTHR30027:SF3 1 248 1.7E-84 T 22-04-2016 HRM2_RS10335 cf87a220a46ea65ab076973d3a92e767 250 SUPERFAMILY SSF88697 1 66 1.82E-15 T 22-04-2016 IPR015947 PUA-like domain HRM2_RS10335 cf87a220a46ea65ab076973d3a92e767 250 Gene3D G3DSA:3.40.1280.10 1 247 5.6E-79 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HRM2_RS10335 cf87a220a46ea65ab076973d3a92e767 250 PIRSF PIRSF015601 1 245 2.3E-64 T 22-04-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HRM2_RS10335 cf87a220a46ea65ab076973d3a92e767 250 Pfam PF04452 RNA methyltransferase 18 240 5.9E-69 T 22-04-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HRM2_RS06035 8f85628897f69ee003c9096d11b3954b 385 Gene3D G3DSA:3.20.20.70 2 303 9.1E-54 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS06035 8f85628897f69ee003c9096d11b3954b 385 Pfam PF00682 HMGL-like 7 261 1.7E-39 T 22-04-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 HRM2_RS06035 8f85628897f69ee003c9096d11b3954b 385 PANTHER PTHR10277:SF9 2 274 1.3E-32 T 22-04-2016 HRM2_RS06035 8f85628897f69ee003c9096d11b3954b 385 SUPERFAMILY SSF51569 3 273 8.79E-45 T 22-04-2016 HRM2_RS06035 8f85628897f69ee003c9096d11b3954b 385 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 198 211 - T 22-04-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 HRM2_RS06035 8f85628897f69ee003c9096d11b3954b 385 PANTHER PTHR10277 2 274 1.3E-32 T 22-04-2016 HRM2_RS05460 f5595deac5032d7426d683da853d6a56 501 Gene3D G3DSA:3.40.50.1100 139 231 1.2E-28 T 22-04-2016 HRM2_RS05460 f5595deac5032d7426d683da853d6a56 501 TIGRFAM TIGR00260 thrC: threonine synthase 87 430 1.2E-55 T 22-04-2016 IPR004450 Threonine synthase-like HRM2_RS05460 f5595deac5032d7426d683da853d6a56 501 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 131 144 - T 22-04-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 HRM2_RS05460 f5595deac5032d7426d683da853d6a56 501 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 104 414 1.4E-46 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HRM2_RS05460 f5595deac5032d7426d683da853d6a56 501 PANTHER PTHR10314:SF5 61 451 7.4E-72 T 22-04-2016 HRM2_RS05460 f5595deac5032d7426d683da853d6a56 501 PANTHER PTHR10314 61 451 7.4E-72 T 22-04-2016 HRM2_RS05460 f5595deac5032d7426d683da853d6a56 501 Gene3D G3DSA:3.40.50.1100 232 423 2.0E-14 T 22-04-2016 HRM2_RS05460 f5595deac5032d7426d683da853d6a56 501 SUPERFAMILY SSF53686 24 441 8.91E-75 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HRM2_RS14395 4cf44f82832e85647b9bfeac6a88ba60 165 Gene3D G3DSA:3.40.630.30 1 159 1.9E-39 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS14395 4cf44f82832e85647b9bfeac6a88ba60 165 SUPERFAMILY SSF55729 2 156 2.09E-24 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS14395 4cf44f82832e85647b9bfeac6a88ba60 165 Pfam PF00583 Acetyltransferase (GNAT) family 47 139 2.0E-13 T 22-04-2016 IPR000182 GNAT domain GO:0008080 HRM2_RS14395 4cf44f82832e85647b9bfeac6a88ba60 165 PANTHER PTHR10908 3 162 3.5E-39 T 22-04-2016 HRM2_RS17610 46c13a76559c5307c6a39ed652551410 322 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 199 280 7.0E-33 T 22-04-2016 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal HRM2_RS17610 46c13a76559c5307c6a39ed652551410 322 SMART SM00893 4 191 2.5E-6 T 22-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 HRM2_RS17610 46c13a76559c5307c6a39ed652551410 322 PANTHER PTHR10909:SF309 107 317 6.8E-45 T 22-04-2016 HRM2_RS17610 46c13a76559c5307c6a39ed652551410 322 PANTHER PTHR10909 107 317 6.8E-45 T 22-04-2016 HRM2_RS17610 46c13a76559c5307c6a39ed652551410 322 SUPERFAMILY SSF52402 4 185 3.35E-23 T 22-04-2016 HRM2_RS17610 46c13a76559c5307c6a39ed652551410 322 Gene3D G3DSA:3.40.50.620 3 189 3.3E-22 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS17610 46c13a76559c5307c6a39ed652551410 322 Pfam PF01012 Electron transfer flavoprotein domain 7 175 1.6E-17 T 22-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 HRM2_RS17610 46c13a76559c5307c6a39ed652551410 322 SUPERFAMILY SSF52467 199 318 2.78E-42 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HRM2_RS17610 46c13a76559c5307c6a39ed652551410 322 Gene3D G3DSA:3.40.50.1220 195 320 2.4E-49 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HRM2_RS17610 46c13a76559c5307c6a39ed652551410 322 PIRSF PIRSF000089 1 322 7.9E-79 T 22-04-2016 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 HRM2_RS03650 0a1908cf171ea3e9f572c8ad4d615744 473 Pfam PF06253 Trimethylamine methyltransferase (MTTB) 4 472 6.8E-153 T 22-04-2016 IPR010426 Trimethylamine methyltransferase GO:0008168|GO:0015948 KEGG: 00680+2.1.1.250|MetaCyc: PWY-5250|UniPathway: UPA00645 HRM2_RS03650 0a1908cf171ea3e9f572c8ad4d615744 473 PIRSF PIRSF037567 1 473 7.1E-140 T 22-04-2016 IPR010426 Trimethylamine methyltransferase GO:0008168|GO:0015948 KEGG: 00680+2.1.1.250|MetaCyc: PWY-5250|UniPathway: UPA00645 HRM2_RS00550 acc448fef3d779b23aecdaabe5ebeed9 71 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 41 52 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS00550 acc448fef3d779b23aecdaabe5ebeed9 71 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS00550 acc448fef3d779b23aecdaabe5ebeed9 71 SUPERFAMILY SSF54862 8 61 8.87E-17 T 22-04-2016 HRM2_RS00550 acc448fef3d779b23aecdaabe5ebeed9 71 Pfam PF12838 4Fe-4S dicluster domain 9 55 6.4E-10 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS00550 acc448fef3d779b23aecdaabe5ebeed9 71 Gene3D G3DSA:3.30.70.20 9 58 8.8E-15 T 22-04-2016 HRM2_RS22595 837febf76e3029cb6033e0717678b2b0 454 SUPERFAMILY SSF53633 1 298 1.7E-67 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HRM2_RS22595 837febf76e3029cb6033e0717678b2b0 454 PANTHER PTHR21499:SF3 3 454 6.0E-105 T 22-04-2016 HRM2_RS22595 837febf76e3029cb6033e0717678b2b0 454 Pfam PF13840 ACT domain 313 374 1.9E-6 T 22-04-2016 IPR027795 GATS-like ACT domain HRM2_RS22595 837febf76e3029cb6033e0717678b2b0 454 Pfam PF13840 ACT domain 392 451 1.2E-8 T 22-04-2016 IPR027795 GATS-like ACT domain HRM2_RS22595 837febf76e3029cb6033e0717678b2b0 454 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 454 3.2E-103 T 22-04-2016 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 HRM2_RS22595 837febf76e3029cb6033e0717678b2b0 454 SUPERFAMILY SSF55021 379 454 2.89E-18 T 22-04-2016 HRM2_RS22595 837febf76e3029cb6033e0717678b2b0 454 Gene3D G3DSA:3.40.1160.10 1 47 1.3E-50 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HRM2_RS22595 837febf76e3029cb6033e0717678b2b0 454 Gene3D G3DSA:3.40.1160.10 108 299 1.3E-50 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HRM2_RS22595 837febf76e3029cb6033e0717678b2b0 454 SUPERFAMILY SSF55021 305 397 5.79E-13 T 22-04-2016 HRM2_RS22595 837febf76e3029cb6033e0717678b2b0 454 Pfam PF00696 Amino acid kinase family 2 285 1.2E-37 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HRM2_RS22595 837febf76e3029cb6033e0717678b2b0 454 PANTHER PTHR21499 3 454 6.0E-105 T 22-04-2016 HRM2_RS22595 837febf76e3029cb6033e0717678b2b0 454 PIRSF PIRSF000726 1 454 4.7E-98 T 22-04-2016 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 HRM2_RS05565 aa31adc7cec20d3018a3b5d2a71719ee 903 SMART SM00487 424 619 7.3E-29 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HRM2_RS05565 aa31adc7cec20d3018a3b5d2a71719ee 903 SUPERFAMILY SSF52540 719 900 1.69E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05565 aa31adc7cec20d3018a3b5d2a71719ee 903 SUPERFAMILY SSF52540 553 606 1.69E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05565 aa31adc7cec20d3018a3b5d2a71719ee 903 PANTHER PTHR10799 374 384 1.4E-134 T 22-04-2016 HRM2_RS05565 aa31adc7cec20d3018a3b5d2a71719ee 903 PANTHER PTHR10799 413 901 1.4E-134 T 22-04-2016 HRM2_RS05565 aa31adc7cec20d3018a3b5d2a71719ee 903 Gene3D G3DSA:3.40.50.300 422 605 9.6E-25 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05565 aa31adc7cec20d3018a3b5d2a71719ee 903 SMART SM00490 762 842 6.6E-16 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS05565 aa31adc7cec20d3018a3b5d2a71719ee 903 Pfam PF12419 SNF2 Helicase protein 248 379 3.2E-25 T 22-04-2016 IPR022138 Helicase SWF/SNF-related HRM2_RS05565 aa31adc7cec20d3018a3b5d2a71719ee 903 Gene3D G3DSA:3.40.50.300 725 873 6.5E-19 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS05565 aa31adc7cec20d3018a3b5d2a71719ee 903 Pfam PF00176 SNF2 family N-terminal domain 446 714 6.8E-49 T 22-04-2016 IPR000330 SNF2-related, N-terminal domain GO:0005524 HRM2_RS05565 aa31adc7cec20d3018a3b5d2a71719ee 903 Pfam PF00271 Helicase conserved C-terminal domain 733 842 1.6E-17 T 22-04-2016 IPR001650 Helicase, C-terminal HRM2_RS05565 aa31adc7cec20d3018a3b5d2a71719ee 903 SUPERFAMILY SSF52540 384 644 4.81E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS17695 fdc309ec409614faa7e02ccd4f5aec3a 116 SUPERFAMILY SSF75169 1 116 1.93E-10 T 22-04-2016 IPR027396 DsrEFH-like HRM2_RS17695 fdc309ec409614faa7e02ccd4f5aec3a 116 Gene3D G3DSA:3.40.1260.10 1 116 6.8E-21 T 22-04-2016 IPR027396 DsrEFH-like HRM2_RS17695 fdc309ec409614faa7e02ccd4f5aec3a 116 Pfam PF02635 DsrE/DsrF-like family 26 116 3.5E-7 T 22-04-2016 IPR003787 Sulphur relay, DsrE/F-like protein HRM2_RS17695 fdc309ec409614faa7e02ccd4f5aec3a 116 ProDom PD052877 ARCHAEL AF0269 3 52 4.0E-12 T 22-04-2016 HRM2_RS12190 2e7eb86a1bbe1c23cdef8aaa4d0fefb9 127 PANTHER PTHR14255 28 120 1.5E-14 T 22-04-2016 HRM2_RS12190 2e7eb86a1bbe1c23cdef8aaa4d0fefb9 127 PANTHER PTHR14255:SF12 28 120 1.5E-14 T 22-04-2016 HRM2_RS12190 2e7eb86a1bbe1c23cdef8aaa4d0fefb9 127 Pfam PF03226 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly 32 125 2.2E-6 T 22-04-2016 IPR004910 Yippee/Mis18/Cereblon HRM2_RS00025 6945923f8ba3b3fc6c337f3e38dc6dfa 141 Pfam PF02472 Biopolymer transport protein ExbD/TolR 11 132 4.6E-29 T 22-04-2016 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 HRM2_RS00025 6945923f8ba3b3fc6c337f3e38dc6dfa 141 SUPERFAMILY SSF53271 37 135 7.53E-6 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like HRM2_RS00025 6945923f8ba3b3fc6c337f3e38dc6dfa 141 PANTHER PTHR30558 6 132 1.2E-25 T 22-04-2016 HRM2_RS02810 97539d6c3c76393b118eb2935f3ccbbb 164 Pfam PF07813 LTXXQ motif family protein 41 139 4.0E-7 T 22-04-2016 IPR012899 LTXXQ motif family protein GO:0042597 HRM2_RS01160 77c06ef7c6a7f2bf0ff6453a8784df13 474 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 48 462 1.5E-82 T 22-04-2016 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 HRM2_RS01160 77c06ef7c6a7f2bf0ff6453a8784df13 474 Gene3D G3DSA:1.20.1600.10 59 465 1.0E-81 T 22-04-2016 HRM2_RS01160 77c06ef7c6a7f2bf0ff6453a8784df13 474 PANTHER PTHR30203 3 462 2.3E-65 T 22-04-2016 HRM2_RS01160 77c06ef7c6a7f2bf0ff6453a8784df13 474 SUPERFAMILY SSF56954 8 31 1.96E-81 T 22-04-2016 HRM2_RS01160 77c06ef7c6a7f2bf0ff6453a8784df13 474 SUPERFAMILY SSF56954 61 464 1.96E-81 T 22-04-2016 HRM2_RS01160 77c06ef7c6a7f2bf0ff6453a8784df13 474 PANTHER PTHR30203:SF3 3 462 2.3E-65 T 22-04-2016 HRM2_RS01160 77c06ef7c6a7f2bf0ff6453a8784df13 474 Pfam PF02321 Outer membrane efflux protein 70 253 6.0E-17 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS01160 77c06ef7c6a7f2bf0ff6453a8784df13 474 Pfam PF02321 Outer membrane efflux protein 284 461 4.2E-16 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS11630 4b9005561522abf2536d30873659c211 161 Pfam PF00588 SpoU rRNA Methylase family 24 147 5.5E-18 T 22-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 HRM2_RS11630 4b9005561522abf2536d30873659c211 161 SUPERFAMILY SSF75217 18 151 1.31E-24 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases HRM2_RS11630 4b9005561522abf2536d30873659c211 161 PANTHER PTHR12029 26 147 9.2E-16 T 22-04-2016 HRM2_RS11630 4b9005561522abf2536d30873659c211 161 Gene3D G3DSA:3.40.1280.10 25 151 7.0E-22 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HRM2_RS23290 4084271a9496bc7af483b9a7d8ea22d1 316 PANTHER PTHR36838 6 314 2.1E-15 T 22-04-2016 HRM2_RS23290 4084271a9496bc7af483b9a7d8ea22d1 316 Pfam PF03547 Membrane transport protein 160 308 4.6E-14 T 22-04-2016 IPR004776 Auxin efflux carrier GO:0016021|GO:0055085 HRM2_RS23290 4084271a9496bc7af483b9a7d8ea22d1 316 Pfam PF03547 Membrane transport protein 8 150 7.3E-8 T 22-04-2016 IPR004776 Auxin efflux carrier GO:0016021|GO:0055085 HRM2_RS03460 18f89b4a7c734cf7600dd6f7130335a7 270 Gene3D G3DSA:3.40.50.300 1 183 6.7E-36 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03460 18f89b4a7c734cf7600dd6f7130335a7 270 Pfam PF13189 Cytidylate kinase-like family 3 167 1.8E-32 T 22-04-2016 IPR026865 Cytidylate kinase-like family MetaCyc: PWY-7205 HRM2_RS18520 a0d5718cc2907c02101898fa7a481699 542 SUPERFAMILY SSF53383 31 532 9.64E-98 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HRM2_RS18520 a0d5718cc2907c02101898fa7a481699 542 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 75 445 1.3E-51 T 22-04-2016 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 HRM2_RS18520 a0d5718cc2907c02101898fa7a481699 542 PANTHER PTHR11999:SF5 100 532 2.0E-102 T 22-04-2016 HRM2_RS18520 a0d5718cc2907c02101898fa7a481699 542 Gene3D G3DSA:3.40.640.10 121 389 2.5E-73 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HRM2_RS18520 a0d5718cc2907c02101898fa7a481699 542 PANTHER PTHR11999 100 532 2.0E-102 T 22-04-2016 HRM2_RS18520 a0d5718cc2907c02101898fa7a481699 542 Gene3D G3DSA:3.90.1150.10 390 532 5.6E-34 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HRM2_RS00620 d8f213d9a56bb3019835e733213f60b6 78 Pfam PF00486 Transcriptional regulatory protein, C terminal 25 77 1.4E-15 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HRM2_RS00620 d8f213d9a56bb3019835e733213f60b6 78 SUPERFAMILY SSF46894 22 77 3.12E-15 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HRM2_RS00620 d8f213d9a56bb3019835e733213f60b6 78 SMART SM00862 21 77 0.001 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HRM2_RS00620 d8f213d9a56bb3019835e733213f60b6 78 Gene3D G3DSA:1.10.10.10 24 77 8.4E-16 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS00620 d8f213d9a56bb3019835e733213f60b6 78 PANTHER PTHR26402:SF578 20 77 3.4E-16 T 22-04-2016 HRM2_RS00620 d8f213d9a56bb3019835e733213f60b6 78 PANTHER PTHR26402 20 77 3.4E-16 T 22-04-2016 HRM2_RS15190 4d9ec2f930386f302688858d220ec668 381 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 174 1.0E-11 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS15190 4d9ec2f930386f302688858d220ec668 381 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 1.7E-8 T 22-04-2016 HRM2_RS15190 4d9ec2f930386f302688858d220ec668 381 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 307 323 1.7E-8 T 22-04-2016 HRM2_RS15190 4d9ec2f930386f302688858d220ec668 381 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.7E-8 T 22-04-2016 HRM2_RS15190 4d9ec2f930386f302688858d220ec668 381 Gene3D G3DSA:3.50.50.60 8 99 8.1E-28 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS15190 4d9ec2f930386f302688858d220ec668 381 Gene3D G3DSA:3.50.50.60 328 377 8.1E-28 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS15190 4d9ec2f930386f302688858d220ec668 381 Gene3D G3DSA:3.50.50.60 142 187 8.1E-28 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS15190 4d9ec2f930386f302688858d220ec668 381 SUPERFAMILY SSF51905 7 373 2.46E-27 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS05590 a036a0b5c2b8920acfdb75d0b86dadc7 285 Pfam PF11356 Type II secretion system protein C 13 156 1.6E-10 T 22-04-2016 IPR024961 Type II secretion system protein C, N-terminal HRM2_RS05590 a036a0b5c2b8920acfdb75d0b86dadc7 285 Pfam PF13180 PDZ domain 216 280 1.8E-7 T 22-04-2016 IPR001478 PDZ domain GO:0005515 HRM2_RS05590 a036a0b5c2b8920acfdb75d0b86dadc7 285 Gene3D G3DSA:2.30.42.10 200 280 7.3E-10 T 22-04-2016 IPR001478 PDZ domain GO:0005515 HRM2_RS05590 a036a0b5c2b8920acfdb75d0b86dadc7 285 SUPERFAMILY SSF50156 187 281 7.49E-15 T 22-04-2016 IPR001478 PDZ domain GO:0005515 HRM2_RS17380 50215a8426dfc95c256f05398c13071b 183 PANTHER PTHR11910 7 181 1.4E-41 T 22-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 HRM2_RS17380 50215a8426dfc95c256f05398c13071b 183 SUPERFAMILY SSF47928 1 107 8.63E-22 T 22-04-2016 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain HRM2_RS17380 50215a8426dfc95c256f05398c13071b 183 Hamap MF_01416 ATP synthase subunit delta [atpD]. 2 179 19.057 T 22-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 HRM2_RS17380 50215a8426dfc95c256f05398c13071b 183 Pfam PF00213 ATP synthase delta (OSCP) subunit 6 177 2.1E-44 T 22-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 HRM2_RS17380 50215a8426dfc95c256f05398c13071b 183 PRINTS PR00125 ATP synthase delta subunit signature 76 87 1.2E-20 T 22-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 HRM2_RS17380 50215a8426dfc95c256f05398c13071b 183 PRINTS PR00125 ATP synthase delta subunit signature 87 101 1.2E-20 T 22-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 HRM2_RS17380 50215a8426dfc95c256f05398c13071b 183 PRINTS PR00125 ATP synthase delta subunit signature 6 25 1.2E-20 T 22-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 HRM2_RS17380 50215a8426dfc95c256f05398c13071b 183 PRINTS PR00125 ATP synthase delta subunit signature 137 152 1.2E-20 T 22-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 HRM2_RS17380 50215a8426dfc95c256f05398c13071b 183 PRINTS PR00125 ATP synthase delta subunit signature 152 170 1.2E-20 T 22-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 HRM2_RS17380 50215a8426dfc95c256f05398c13071b 183 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 6 176 4.3E-33 T 22-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 HRM2_RS17380 50215a8426dfc95c256f05398c13071b 183 Gene3D G3DSA:1.10.520.20 4 107 9.9E-18 T 22-04-2016 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain HRM2_RS14155 401af597efb64f9f07d5586c741f947e 244 Gene3D G3DSA:3.30.1330.60 114 237 4.2E-33 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS14155 401af597efb64f9f07d5586c741f947e 244 SUPERFAMILY SSF103088 120 237 3.79E-32 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS14155 401af597efb64f9f07d5586c741f947e 244 Pfam PF00691 OmpA family 132 231 2.5E-17 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS14155 401af597efb64f9f07d5586c741f947e 244 PANTHER PTHR30329:SF4 19 240 1.2E-42 T 22-04-2016 HRM2_RS14155 401af597efb64f9f07d5586c741f947e 244 PANTHER PTHR30329 19 240 1.2E-42 T 22-04-2016 HRM2_RS14155 401af597efb64f9f07d5586c741f947e 244 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 16 54 3.7E-16 T 22-04-2016 IPR025713 Motility protein B, N-terminal domain HRM2_RS19915 6344d5229a765a6b2f39446a79a31662 407 Gene3D G3DSA:1.20.1250.20 24 207 1.9E-38 T 22-04-2016 HRM2_RS19915 6344d5229a765a6b2f39446a79a31662 407 Gene3D G3DSA:1.20.1250.20 225 402 5.9E-23 T 22-04-2016 HRM2_RS19915 6344d5229a765a6b2f39446a79a31662 407 SUPERFAMILY SSF103473 22 403 1.15E-69 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS19915 6344d5229a765a6b2f39446a79a31662 407 PANTHER PTHR23504 8 394 5.2E-54 T 22-04-2016 HRM2_RS19915 6344d5229a765a6b2f39446a79a31662 407 PRINTS PR01035 Tetracycline resistance protein signature 36 52 1.2E-6 T 22-04-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 HRM2_RS19915 6344d5229a765a6b2f39446a79a31662 407 PRINTS PR01035 Tetracycline resistance protein signature 316 336 1.2E-6 T 22-04-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 HRM2_RS19915 6344d5229a765a6b2f39446a79a31662 407 PRINTS PR01035 Tetracycline resistance protein signature 151 173 1.2E-6 T 22-04-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 HRM2_RS19915 6344d5229a765a6b2f39446a79a31662 407 Pfam PF07690 Major Facilitator Superfamily 30 339 1.6E-44 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS01910 682e6c2a52188e2e4118fefccfbdf84a 123 Pfam PF01844 HNH endonuclease 52 107 3.2E-10 T 22-04-2016 IPR002711 HNH endonuclease GO:0003676|GO:0004519 HRM2_RS01910 682e6c2a52188e2e4118fefccfbdf84a 123 SMART SM00507 39 103 0.0026 T 22-04-2016 IPR003615 HNH nuclease HRM2_RS11375 f55b597a6c98b719fde26f8c9d29629b 750 PANTHER PTHR11101 1 85 1.8E-14 T 22-04-2016 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: REACT_15518 HRM2_RS11375 f55b597a6c98b719fde26f8c9d29629b 750 PANTHER PTHR11101 404 496 1.8E-14 T 22-04-2016 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: REACT_15518 HRM2_RS11375 f55b597a6c98b719fde26f8c9d29629b 750 PANTHER PTHR11101:SF16 1 85 1.8E-14 T 22-04-2016 HRM2_RS11375 f55b597a6c98b719fde26f8c9d29629b 750 PANTHER PTHR11101:SF16 404 496 1.8E-14 T 22-04-2016 HRM2_RS11375 f55b597a6c98b719fde26f8c9d29629b 750 Pfam PF01384 Phosphate transporter family 27 327 2.5E-22 T 22-04-2016 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: REACT_15518 HRM2_RS04230 197871a55c295cf242cb0449d00ad1c6 414 Pfam PF00483 Nucleotidyl transferase 6 262 5.7E-59 T 22-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 HRM2_RS04230 197871a55c295cf242cb0449d00ad1c6 414 PANTHER PTHR22572 5 414 1.1E-145 T 22-04-2016 HRM2_RS04230 197871a55c295cf242cb0449d00ad1c6 414 PANTHER PTHR22572:SF79 5 414 1.1E-145 T 22-04-2016 HRM2_RS04230 197871a55c295cf242cb0449d00ad1c6 414 SUPERFAMILY SSF53448 308 324 4.22E-71 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS04230 197871a55c295cf242cb0449d00ad1c6 414 SUPERFAMILY SSF53448 2 265 4.22E-71 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS04230 197871a55c295cf242cb0449d00ad1c6 414 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 96 104 - T 22-04-2016 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 HRM2_RS04230 197871a55c295cf242cb0449d00ad1c6 414 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 199 209 - T 22-04-2016 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 HRM2_RS04230 197871a55c295cf242cb0449d00ad1c6 414 SUPERFAMILY SSF51161 279 414 9.9E-21 T 22-04-2016 IPR011004 Trimeric LpxA-like HRM2_RS04230 197871a55c295cf242cb0449d00ad1c6 414 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 10 29 - T 22-04-2016 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 HRM2_RS04230 197871a55c295cf242cb0449d00ad1c6 414 Gene3D G3DSA:3.90.550.10 6 332 5.5E-67 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS06640 4b9e9d1856af4d81afbb6de7b419091c 109 Pfam PF12966 N-ATPase, AtpR subunit 6 89 7.0E-26 T 22-04-2016 IPR017581 N-ATPase, AtpR subunit-like HRM2_RS06640 4b9e9d1856af4d81afbb6de7b419091c 109 TIGRFAM TIGR03165 F1F0_chp_2: F1/F0 ATPase, Methanosarcina type, subunit 2 7 86 1.1E-17 T 22-04-2016 IPR017581 N-ATPase, AtpR subunit-like HRM2_RS15285 c454e5d265cfa271ca9227d05596d36c 115 ProSitePatterns PS01015 Ribosomal protein L19 signature. 85 100 - T 22-04-2016 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS15285 c454e5d265cfa271ca9227d05596d36c 115 SUPERFAMILY SSF50104 1 112 2.51E-45 T 22-04-2016 IPR008991 Translation protein SH3-like domain HRM2_RS15285 c454e5d265cfa271ca9227d05596d36c 115 PRINTS PR00061 Ribosomal protein L19 signature 87 112 1.8E-38 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS15285 c454e5d265cfa271ca9227d05596d36c 115 PRINTS PR00061 Ribosomal protein L19 signature 3 32 1.8E-38 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS15285 c454e5d265cfa271ca9227d05596d36c 115 PRINTS PR00061 Ribosomal protein L19 signature 33 62 1.8E-38 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS15285 c454e5d265cfa271ca9227d05596d36c 115 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 113 29.846 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS15285 c454e5d265cfa271ca9227d05596d36c 115 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 1 112 3.1E-45 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS15285 c454e5d265cfa271ca9227d05596d36c 115 Pfam PF01245 Ribosomal protein L19 2 112 5.7E-48 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS15285 c454e5d265cfa271ca9227d05596d36c 115 PIRSF PIRSF002191 1 115 3.8E-47 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS15285 c454e5d265cfa271ca9227d05596d36c 115 PANTHER PTHR15680 2 113 4.0E-46 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS04135 3603172317c18cde1da22586ab7f0853 218 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 110 3.3E-23 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HRM2_RS04135 3603172317c18cde1da22586ab7f0853 218 Gene3D G3DSA:1.10.3720.10 15 213 4.5E-44 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS04135 3603172317c18cde1da22586ab7f0853 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 211 3.3E-19 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS04135 3603172317c18cde1da22586ab7f0853 218 SUPERFAMILY SSF161098 15 204 3.79E-40 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS04135 3603172317c18cde1da22586ab7f0853 218 PANTHER PTHR30614 1 212 8.5E-78 T 22-04-2016 HRM2_RS14150 a5f78caa37e1345c56c8d3191e3a87ae 256 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 182 199 - T 22-04-2016 IPR000540 Flagellar motor protein MotA, conserved site HRM2_RS14150 a5f78caa37e1345c56c8d3191e3a87ae 256 PANTHER PTHR30433 2 254 2.0E-78 T 22-04-2016 HRM2_RS14150 a5f78caa37e1345c56c8d3191e3a87ae 256 Pfam PF01618 MotA/TolQ/ExbB proton channel family 105 211 1.2E-18 T 22-04-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 HRM2_RS14150 a5f78caa37e1345c56c8d3191e3a87ae 256 PANTHER PTHR30433:SF2 2 254 2.0E-78 T 22-04-2016 IPR022522 Flagellar motor stator, MotA HRM2_RS09725 2d0b7ccaca7438cd1d57719bd69052ec 118 PANTHER PTHR11075 18 116 1.7E-25 T 22-04-2016 HRM2_RS09725 2d0b7ccaca7438cd1d57719bd69052ec 118 Pfam PF00472 RF-1 domain 18 114 1.1E-23 T 22-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 HRM2_RS09725 2d0b7ccaca7438cd1d57719bd69052ec 118 SUPERFAMILY SSF75620 17 84 3.66E-23 T 22-04-2016 HRM2_RS09725 2d0b7ccaca7438cd1d57719bd69052ec 118 Gene3D G3DSA:3.30.160.20 18 88 3.6E-26 T 22-04-2016 IPR014720 Double-stranded RNA-binding domain HRM2_RS19025 ee49114e11decaa29f4873498681315c 371 PANTHER PTHR32154 211 370 9.3E-91 T 22-04-2016 HRM2_RS19025 ee49114e11decaa29f4873498681315c 371 PANTHER PTHR32154 5 184 9.3E-91 T 22-04-2016 HRM2_RS19025 ee49114e11decaa29f4873498681315c 371 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 15 238 1.1E-52 T 22-04-2016 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 HRM2_RS19025 ee49114e11decaa29f4873498681315c 371 Gene3D G3DSA:3.40.50.970 4 183 2.6E-66 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS19025 ee49114e11decaa29f4873498681315c 371 SUPERFAMILY SSF52922 262 370 4.06E-21 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HRM2_RS19025 ee49114e11decaa29f4873498681315c 371 SUPERFAMILY SSF52518 4 252 7.2E-53 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS19025 ee49114e11decaa29f4873498681315c 371 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 271 362 3.6E-14 T 22-04-2016 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II HRM2_RS19025 ee49114e11decaa29f4873498681315c 371 Gene3D G3DSA:3.40.50.920 262 370 3.2E-18 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HRM2_RS19025 ee49114e11decaa29f4873498681315c 371 PANTHER PTHR32154:SF14 211 370 9.3E-91 T 22-04-2016 HRM2_RS19025 ee49114e11decaa29f4873498681315c 371 PANTHER PTHR32154:SF14 5 184 9.3E-91 T 22-04-2016 HRM2_RS09875 307d45df481a726480dba950a3036f76 352 Pfam PF14397 Sugar-transfer associated ATP-grasp 79 345 8.0E-37 T 22-04-2016 HRM2_RS09875 307d45df481a726480dba950a3036f76 352 SUPERFAMILY SSF56059 72 217 4.32E-12 T 22-04-2016 HRM2_RS09875 307d45df481a726480dba950a3036f76 352 SUPERFAMILY SSF56059 278 330 4.32E-12 T 22-04-2016 HRM2_RS02570 164da37f3335fcea8fd6a8db15a5df19 248 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 4 245 2.7E-92 T 22-04-2016 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 HRM2_RS02570 164da37f3335fcea8fd6a8db15a5df19 248 Gene3D G3DSA:3.40.50.1580 2 247 6.9E-91 T 22-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HRM2_RS02570 164da37f3335fcea8fd6a8db15a5df19 248 SUPERFAMILY SSF53167 1 247 6.28E-87 T 22-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HRM2_RS02570 164da37f3335fcea8fd6a8db15a5df19 248 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 2 248 37.961 T 22-04-2016 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 HRM2_RS02570 164da37f3335fcea8fd6a8db15a5df19 248 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 50 90 - T 22-04-2016 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 HRM2_RS02570 164da37f3335fcea8fd6a8db15a5df19 248 PANTHER PTHR11904:SF1 1 247 5.7E-122 T 22-04-2016 HRM2_RS02570 164da37f3335fcea8fd6a8db15a5df19 248 PANTHER PTHR11904 1 247 5.7E-122 T 22-04-2016 IPR001369 PNP/MTAP phosphorylase HRM2_RS02570 164da37f3335fcea8fd6a8db15a5df19 248 Pfam PF01048 Phosphorylase superfamily 3 244 8.2E-51 T 22-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HRM2_RS05605 f2036ed5c87408a55e961df29872fb67 477 Pfam PF11104 Type IV pilus assembly protein PilM; 7 210 9.5E-8 T 22-04-2016 IPR005883 Type IV pilus assembly protein PilM HRM2_RS05605 f2036ed5c87408a55e961df29872fb67 477 Gene3D G3DSA:3.30.420.40 3 90 1.4E-4 T 22-04-2016 HRM2_RS05605 f2036ed5c87408a55e961df29872fb67 477 SUPERFAMILY SSF53067 71 165 1.94E-6 T 22-04-2016 HRM2_RS05605 f2036ed5c87408a55e961df29872fb67 477 Pfam PF05137 Fimbrial assembly protein (PilN) 401 476 9.8E-7 T 22-04-2016 IPR007813 Fimbrial assembly PilN HRM2_RS00995 71ab3cda3a9fb52c3d0303d5b60147e0 394 PANTHER PTHR35271 137 387 2.4E-21 T 22-04-2016 HRM2_RS00995 71ab3cda3a9fb52c3d0303d5b60147e0 394 Gene3D G3DSA:3.40.50.2300 209 350 3.8E-12 T 22-04-2016 HRM2_RS00995 71ab3cda3a9fb52c3d0303d5b60147e0 394 Pfam PF04392 ABC transporter substrate binding protein 136 385 5.2E-25 T 22-04-2016 IPR007487 ABC transporter, substrate-binding protein HRM2_RS00995 71ab3cda3a9fb52c3d0303d5b60147e0 394 Gene3D G3DSA:3.40.50.2300 46 208 4.3E-33 T 22-04-2016 HRM2_RS24215 3cdbac4d1af7c392092f02dd91a22093 111 SUPERFAMILY SSF143011 1 85 2.35E-8 T 22-04-2016 HRM2_RS20860 d324e2d79d752f6eb405ce671f467350 117 PANTHER PTHR33162 1 73 3.1E-19 T 22-04-2016 HRM2_RS20860 d324e2d79d752f6eb405ce671f467350 117 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 91 16.928 T 22-04-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 HRM2_RS20860 d324e2d79d752f6eb405ce671f467350 117 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 47 3.3E-16 T 22-04-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 HRM2_RS20860 d324e2d79d752f6eb405ce671f467350 117 PANTHER PTHR33162:SF1 1 73 3.1E-19 T 22-04-2016 HRM2_RS20860 d324e2d79d752f6eb405ce671f467350 117 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 3.4E-8 T 22-04-2016 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 HRM2_RS20860 d324e2d79d752f6eb405ce671f467350 117 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 3.4E-8 T 22-04-2016 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 HRM2_RS20860 d324e2d79d752f6eb405ce671f467350 117 Pfam PF02416 mttA/Hcf106 family 4 49 9.1E-17 T 22-04-2016 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 HRM2_RS08525 4508e771b10ce01d2b28b7c199888d28 255 Pfam PF01255 Putative undecaprenyl diphosphate synthase 23 243 2.5E-85 T 22-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 HRM2_RS08525 4508e771b10ce01d2b28b7c199888d28 255 Gene3D G3DSA:3.40.1180.10 8 245 1.8E-104 T 22-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 HRM2_RS08525 4508e771b10ce01d2b28b7c199888d28 255 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 189 206 - T 22-04-2016 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 HRM2_RS08525 4508e771b10ce01d2b28b7c199888d28 255 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 16 244 40.607 T 22-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 HRM2_RS08525 4508e771b10ce01d2b28b7c199888d28 255 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 16 243 2.4E-91 T 22-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 HRM2_RS08525 4508e771b10ce01d2b28b7c199888d28 255 SUPERFAMILY SSF64005 13 239 6.02E-88 T 22-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 HRM2_RS08525 4508e771b10ce01d2b28b7c199888d28 255 PANTHER PTHR10291 11 245 5.9E-122 T 22-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 HRM2_RS23180 13b531c41aae08470308ac1ddc41d7b1 361 Pfam PF13515 Fusaric acid resistance protein-like 33 155 3.2E-22 T 22-04-2016 HRM2_RS23180 13b531c41aae08470308ac1ddc41d7b1 361 PANTHER PTHR30509 16 253 4.9E-27 T 22-04-2016 HRM2_RS00425 fa6c1a95768eb238fc761d483dc78b28 292 Gene3D G3DSA:1.20.120.450 16 138 3.7E-8 T 22-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase HRM2_RS00425 fa6c1a95768eb238fc761d483dc78b28 292 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 33 245 3.8E-31 T 22-04-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type HRM2_RS00425 fa6c1a95768eb238fc761d483dc78b28 292 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 31 167 1.1E-22 T 22-04-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 HRM2_RS00425 fa6c1a95768eb238fc761d483dc78b28 292 TIGRFAM TIGR03084 TIGR03084: TIGR03084 family protein 24 277 2.8E-82 T 22-04-2016 IPR017518 Conserved hypothetical protein CHP03084 HRM2_RS00425 fa6c1a95768eb238fc761d483dc78b28 292 SUPERFAMILY SSF109854 26 170 2.14E-23 T 22-04-2016 HRM2_RS09800 3501134955ecaca59619ced26c973767 141 Pfam PF01934 Protein of unknown function DUF86 16 133 6.0E-20 T 22-04-2016 IPR008201 Protein of unknown function DUF86 HRM2_RS09800 3501134955ecaca59619ced26c973767 141 PANTHER PTHR33397 33 141 8.0E-12 T 22-04-2016 HRM2_RS09800 3501134955ecaca59619ced26c973767 141 Gene3D G3DSA:1.20.120.580 1 138 6.1E-31 T 22-04-2016 HRM2_RS03275 88ef5138b93353f435c9ced7c40a6ae7 439 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 3 425 5.3E-153 T 22-04-2016 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890|UniPathway: UPA00060 HRM2_RS03275 88ef5138b93353f435c9ced7c40a6ae7 439 PANTHER PTHR30557:SF1 1 420 2.1E-194 T 22-04-2016 HRM2_RS03275 88ef5138b93353f435c9ced7c40a6ae7 439 PANTHER PTHR30557 1 420 2.1E-194 T 22-04-2016 HRM2_RS03275 88ef5138b93353f435c9ced7c40a6ae7 439 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 2 429 48.713 T 22-04-2016 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890|UniPathway: UPA00060 HRM2_RS03275 88ef5138b93353f435c9ced7c40a6ae7 439 Pfam PF01964 Radical SAM ThiC family 3 421 3.3E-165 T 22-04-2016 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890|UniPathway: UPA00060 HRM2_RS03275 88ef5138b93353f435c9ced7c40a6ae7 439 SUPERFAMILY SSF51703 293 374 5.96E-5 T 22-04-2016 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 HRM2_RS10620 c1f0c1568df68f4584923bd17e4abc1e 105 Pfam PF01371 Trp repressor protein 8 90 2.2E-17 T 22-04-2016 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 HRM2_RS10620 c1f0c1568df68f4584923bd17e4abc1e 105 PANTHER PTHR38025 10 97 1.7E-12 T 22-04-2016 HRM2_RS10620 c1f0c1568df68f4584923bd17e4abc1e 105 SUPERFAMILY SSF48295 2 90 2.3E-19 T 22-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 HRM2_RS10620 c1f0c1568df68f4584923bd17e4abc1e 105 Gene3D G3DSA:1.10.1270.10 5 93 7.5E-23 T 22-04-2016 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 HRM2_RS10620 c1f0c1568df68f4584923bd17e4abc1e 105 ProDom PD012582 REPRESSOR TRANSCRIPTION TRP OPERON DNA-BINDING REGULATION HOMOLOG AROH FOR TRYPTOPHAN 27 78 8.0E-6 T 22-04-2016 IPR013335 Trp repressor, bacterial GO:0006355 HRM2_RS10620 c1f0c1568df68f4584923bd17e4abc1e 105 PANTHER PTHR38025:SF1 10 97 1.7E-12 T 22-04-2016 HRM2_RS02600 d83a0de4549c48ba72369f93dd74031d 407 Gene3D G3DSA:1.10.10.10 336 379 5.0E-5 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS02600 d83a0de4549c48ba72369f93dd74031d 407 SUPERFAMILY SSF46785 335 396 7.03E-6 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS22490 c87e92be1a1cc37b388cfc144050748d 157 PANTHER PTHR35011 6 153 8.5E-16 T 22-04-2016 HRM2_RS22490 c87e92be1a1cc37b388cfc144050748d 157 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 19 139 5.1E-21 T 22-04-2016 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component HRM2_RS07575 b9277f56ce3f3e76363be30d8ed2ed30 117 TIGRFAM TIGR03912 PylS_Nterm: pyrrolysine--tRNA ligase, N-terminal region 18 106 1.7E-43 T 22-04-2016 IPR023878 Pyrrolysyl-tRNA ligase, N-terminal GO:0016876 KEGG: 00970+6.1.1.26 HRM2_RS21655 908b30d0f9ea123f184e50bffe859452 205 Gene3D G3DSA:3.40.50.150 3 189 7.4E-25 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS21655 908b30d0f9ea123f184e50bffe859452 205 PANTHER PTHR10108 4 157 3.0E-17 T 22-04-2016 HRM2_RS21655 908b30d0f9ea123f184e50bffe859452 205 SUPERFAMILY SSF53335 8 187 2.46E-25 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS21655 908b30d0f9ea123f184e50bffe859452 205 Pfam PF13649 Methyltransferase domain 39 130 2.2E-15 T 22-04-2016 HRM2_RS09840 1f7ebad74d0c632e0d0855d096b5365b 414 TIGRFAM TIGR03087 stp1: sugar transferase, PEP-CTERM/EpsH1 system associated 3 408 1.4E-137 T 22-04-2016 IPR017521 Sugar transferase, PEP-CTERM, Stp1 HRM2_RS09840 1f7ebad74d0c632e0d0855d096b5365b 414 PANTHER PTHR12526 175 407 2.7E-23 T 22-04-2016 HRM2_RS09840 1f7ebad74d0c632e0d0855d096b5365b 414 SUPERFAMILY SSF53756 2 406 7.63E-39 T 22-04-2016 HRM2_RS09840 1f7ebad74d0c632e0d0855d096b5365b 414 Gene3D G3DSA:3.40.50.2000 202 352 4.7E-5 T 22-04-2016 HRM2_RS09840 1f7ebad74d0c632e0d0855d096b5365b 414 Pfam PF13692 Glycosyl transferases group 1 237 373 7.2E-31 T 22-04-2016 HRM2_RS07905 d51fe34baa4c8e1689a122457cdad789 83 SUPERFAMILY SSF52242 1 82 3.66E-24 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS07905 d51fe34baa4c8e1689a122457cdad789 83 Gene3D G3DSA:3.40.50.280 1 82 1.8E-26 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS07905 d51fe34baa4c8e1689a122457cdad789 83 Pfam PF02310 B12 binding domain 2 70 3.3E-14 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS08115 bd88ac34e9131682dc90e7e620649a1d 453 PANTHER PTHR32024 14 453 8.5E-154 T 22-04-2016 HRM2_RS08115 bd88ac34e9131682dc90e7e620649a1d 453 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 27 425 3.4E-100 T 22-04-2016 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 HRM2_RS08115 bd88ac34e9131682dc90e7e620649a1d 453 PANTHER PTHR32024:SF1 14 453 8.5E-154 T 22-04-2016 HRM2_RS08115 bd88ac34e9131682dc90e7e620649a1d 453 Pfam PF02386 Cation transport protein 37 431 6.7E-62 T 22-04-2016 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 HRM2_RS05595 f78e3890e47594cd52a291b6c2c7a0c7 290 Pfam PF13502 AsmA-like C-terminal region 100 286 2.1E-5 T 22-04-2016 IPR032712 AsmA-like, C-terminal HRM2_RS05595 f78e3890e47594cd52a291b6c2c7a0c7 290 TIGRFAM TIGR04411 T2SS_GspN_Lepto: type II secretion system protein N 5 288 1.5E-68 T 22-04-2016 IPR030925 Type II secretion system protein N, Leptospira-type HRM2_RS19775 ce05f9bc9c177e7f25d3c1d601fc2e15 473 SUPERFAMILY SSF56954 23 471 3.01E-85 T 22-04-2016 HRM2_RS19775 ce05f9bc9c177e7f25d3c1d601fc2e15 473 Gene3D G3DSA:1.20.1600.10 53 471 4.7E-71 T 22-04-2016 HRM2_RS19775 ce05f9bc9c177e7f25d3c1d601fc2e15 473 Pfam PF02321 Outer membrane efflux protein 291 471 3.4E-34 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS19775 ce05f9bc9c177e7f25d3c1d601fc2e15 473 Pfam PF02321 Outer membrane efflux protein 58 269 3.4E-23 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS19775 ce05f9bc9c177e7f25d3c1d601fc2e15 473 PANTHER PTHR30026 1 473 2.5E-57 T 22-04-2016 HRM2_RS11300 d48a241f50ea816c4926beb7a1610817 131 SUPERFAMILY SSF53098 63 118 8.09E-5 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS11300 d48a241f50ea816c4926beb7a1610817 131 Gene3D G3DSA:3.30.420.10 60 117 2.1E-5 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS14705 3851ddf35ee2c952cb69ce3cf423c050 319 PANTHER PTHR22926 30 317 1.5E-54 T 22-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HRM2_RS14705 3851ddf35ee2c952cb69ce3cf423c050 319 PANTHER PTHR22926:SF3 30 317 1.5E-54 T 22-04-2016 HRM2_RS14705 3851ddf35ee2c952cb69ce3cf423c050 319 Pfam PF00953 Glycosyl transferase family 4 68 207 6.0E-28 T 22-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HRM2_RS07255 92b26615d716737bd50caa78fa2c7d78 339 PANTHER PTHR30365 3 339 3.7E-125 T 22-04-2016 HRM2_RS07255 92b26615d716737bd50caa78fa2c7d78 339 PANTHER PTHR30365:SF4 3 339 3.7E-125 T 22-04-2016 HRM2_RS07255 92b26615d716737bd50caa78fa2c7d78 339 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 10 201 7.1E-42 T 22-04-2016 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 HRM2_RS07255 92b26615d716737bd50caa78fa2c7d78 339 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 10 329 2.9E-91 T 22-04-2016 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 HRM2_RS20305 b20943cb3ddc6f90f91021e1563bf7e6 312 SUPERFAMILY SSF103481 226 310 6.41E-11 T 22-04-2016 HRM2_RS20305 b20943cb3ddc6f90f91021e1563bf7e6 312 SUPERFAMILY SSF103481 63 161 3.53E-11 T 22-04-2016 HRM2_RS20305 b20943cb3ddc6f90f91021e1563bf7e6 312 PANTHER PTHR22911 27 312 1.4E-44 T 22-04-2016 HRM2_RS20305 b20943cb3ddc6f90f91021e1563bf7e6 312 PANTHER PTHR22911:SF23 27 312 1.4E-44 T 22-04-2016 HRM2_RS20305 b20943cb3ddc6f90f91021e1563bf7e6 312 Pfam PF00892 EamA-like transporter family 27 161 4.8E-21 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS20305 b20943cb3ddc6f90f91021e1563bf7e6 312 Pfam PF00892 EamA-like transporter family 174 306 7.3E-18 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS04690 ac6111462d3ecf6b912e8279f15dd19e 239 Pfam PF03803 Scramblase 36 236 2.8E-38 T 22-04-2016 IPR005552 Scramblase HRM2_RS04690 ac6111462d3ecf6b912e8279f15dd19e 239 SUPERFAMILY SSF54518 106 233 3.66E-8 T 22-04-2016 IPR025659 Tubby C-terminal-like domain HRM2_RS04690 ac6111462d3ecf6b912e8279f15dd19e 239 PANTHER PTHR23248 45 239 2.8E-45 T 22-04-2016 IPR005552 Scramblase HRM2_RS12650 e6c6211f387901f989f8ef80e5ff7c3b 546 PANTHER PTHR34614 1 534 1.6E-123 T 22-04-2016 HRM2_RS12650 e6c6211f387901f989f8ef80e5ff7c3b 546 Pfam PF01609 Transposase DDE domain 151 452 2.1E-7 T 22-04-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 HRM2_RS12650 e6c6211f387901f989f8ef80e5ff7c3b 546 Pfam PF14104 Domain of unknown function (DUF4277) 4 110 5.9E-38 T 22-04-2016 IPR025457 Domain of unknown function DUF4277 HRM2_RS19020 18fd999c22623b1c8dc196dcca4e4bdc 431 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 276 389 3.9E-7 T 22-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HRM2_RS19020 18fd999c22623b1c8dc196dcca4e4bdc 431 SUPERFAMILY SSF53323 265 377 1.24E-7 T 22-04-2016 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 HRM2_RS19020 18fd999c22623b1c8dc196dcca4e4bdc 431 PANTHER PTHR18968:SF89 7 234 1.3E-57 T 22-04-2016 HRM2_RS19020 18fd999c22623b1c8dc196dcca4e4bdc 431 SUPERFAMILY SSF52518 9 240 1.01E-52 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS19020 18fd999c22623b1c8dc196dcca4e4bdc 431 Gene3D G3DSA:3.40.920.10 263 427 5.4E-9 T 22-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HRM2_RS19020 18fd999c22623b1c8dc196dcca4e4bdc 431 PANTHER PTHR18968 7 234 1.3E-57 T 22-04-2016 HRM2_RS19020 18fd999c22623b1c8dc196dcca4e4bdc 431 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 45 190 5.5E-27 T 22-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HRM2_RS19020 18fd999c22623b1c8dc196dcca4e4bdc 431 Gene3D G3DSA:3.40.50.970 9 201 1.8E-50 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS15610 4a600822638d4804818293f29e95f9e0 454 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 410 425 3.4E-42 T 22-04-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 HRM2_RS15610 4a600822638d4804818293f29e95f9e0 454 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 120 140 3.4E-42 T 22-04-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 HRM2_RS15610 4a600822638d4804818293f29e95f9e0 454 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 159 176 3.4E-42 T 22-04-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 HRM2_RS15610 4a600822638d4804818293f29e95f9e0 454 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 282 300 3.4E-42 T 22-04-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 HRM2_RS15610 4a600822638d4804818293f29e95f9e0 454 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 87 103 3.4E-42 T 22-04-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 HRM2_RS15610 4a600822638d4804818293f29e95f9e0 454 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 321 337 3.4E-42 T 22-04-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 HRM2_RS15610 4a600822638d4804818293f29e95f9e0 454 Pfam PF02127 Aminopeptidase I zinc metalloprotease (M18) 23 441 1.5E-132 T 22-04-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 HRM2_RS15610 4a600822638d4804818293f29e95f9e0 454 PANTHER PTHR28570 12 453 5.7E-160 T 22-04-2016 HRM2_RS15610 4a600822638d4804818293f29e95f9e0 454 Gene3D G3DSA:2.30.250.10 98 238 1.4E-34 T 22-04-2016 IPR023358 Peptidase M18, domain 2 GO:0004177 HRM2_RS15610 4a600822638d4804818293f29e95f9e0 454 SUPERFAMILY SSF53187 234 443 2.51E-97 T 22-04-2016 HRM2_RS15610 4a600822638d4804818293f29e95f9e0 454 SUPERFAMILY SSF53187 14 98 2.51E-97 T 22-04-2016 HRM2_RS15610 4a600822638d4804818293f29e95f9e0 454 SUPERFAMILY SSF101821 99 232 3.2E-29 T 22-04-2016 HRM2_RS15610 4a600822638d4804818293f29e95f9e0 454 Gene3D G3DSA:3.40.630.10 243 443 1.7E-110 T 22-04-2016 HRM2_RS15610 4a600822638d4804818293f29e95f9e0 454 Gene3D G3DSA:3.40.630.10 15 97 1.7E-110 T 22-04-2016 HRM2_RS07065 5b627daeb5f2ad3cc2c8b41b7e08278c 358 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 6 344 7.3E-56 T 22-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 HRM2_RS07065 5b627daeb5f2ad3cc2c8b41b7e08278c 358 SUPERFAMILY SSF51726 3 345 9.77E-58 T 22-04-2016 HRM2_RS07065 5b627daeb5f2ad3cc2c8b41b7e08278c 358 Gene3D G3DSA:3.20.20.210 2 345 2.1E-47 T 22-04-2016 HRM2_RS22085 4864c184b4298a32adb2c76b44c9706e 295 Pfam PF01256 Carbohydrate kinase 115 257 1.1E-7 T 22-04-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 HRM2_RS22085 4864c184b4298a32adb2c76b44c9706e 295 Gene3D G3DSA:3.40.1190.20 111 276 1.0E-14 T 22-04-2016 IPR029056 Ribokinase-like HRM2_RS22085 4864c184b4298a32adb2c76b44c9706e 295 SUPERFAMILY SSF53613 94 281 3.64E-20 T 22-04-2016 IPR029056 Ribokinase-like HRM2_RS00470 82ca5b7c753e198808fd0e8b54f5908b 77 Gene3D G3DSA:3.30.300.120 26 69 4.7E-6 T 22-04-2016 HRM2_RS00470 82ca5b7c753e198808fd0e8b54f5908b 77 Hamap MF_00088 UPF0109 protein . 1 75 20.896 T 22-04-2016 IPR020627 Uncharacterised protein family UPF0109 HRM2_RS00470 82ca5b7c753e198808fd0e8b54f5908b 77 SUPERFAMILY SSF54814 6 61 1.9E-6 T 22-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 HRM2_RS00470 82ca5b7c753e198808fd0e8b54f5908b 77 Pfam PF13083 KH domain 2 74 7.6E-21 T 22-04-2016 HRM2_RS00470 82ca5b7c753e198808fd0e8b54f5908b 77 PANTHER PTHR34654 1 77 3.5E-26 T 22-04-2016 HRM2_RS20995 7dc9b528c865a526d55060b1338c2a48 116 Pfam PF07883 Cupin domain 41 108 1.6E-12 T 22-04-2016 IPR013096 Cupin 2, conserved barrel HRM2_RS20995 7dc9b528c865a526d55060b1338c2a48 116 SUPERFAMILY SSF51182 19 112 1.7E-21 T 22-04-2016 IPR011051 RmlC-like cupin domain HRM2_RS20995 7dc9b528c865a526d55060b1338c2a48 116 Gene3D G3DSA:2.60.120.10 1 113 2.7E-26 T 22-04-2016 IPR014710 RmlC-like jelly roll fold HRM2_RS03645 8c4b90e418ed290c24e85a8955b07722 210 SMART SM01018 1 84 1.3E-28 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain HRM2_RS03645 8c4b90e418ed290c24e85a8955b07722 210 SUPERFAMILY SSF52242 69 210 4.19E-42 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS03645 8c4b90e418ed290c24e85a8955b07722 210 Pfam PF02607 B12 binding domain 5 77 8.3E-19 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain HRM2_RS03645 8c4b90e418ed290c24e85a8955b07722 210 Gene3D G3DSA:3.40.50.280 75 209 2.5E-48 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS03645 8c4b90e418ed290c24e85a8955b07722 210 Pfam PF02310 B12 binding domain 90 192 1.4E-25 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 HRM2_RS03645 8c4b90e418ed290c24e85a8955b07722 210 Gene3D G3DSA:1.10.1240.10 5 74 2.8E-21 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain HRM2_RS03645 8c4b90e418ed290c24e85a8955b07722 210 SUPERFAMILY SSF47644 2 83 6.54E-22 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain HRM2_RS08745 ce1f65827c1328e708d2505025b3d57b 129 Pfam PF10722 Putative bacterial sensory transduction regulator 7 124 2.1E-7 T 22-04-2016 IPR019660 Putative sensory transduction regulator YbjN HRM2_RS08745 ce1f65827c1328e708d2505025b3d57b 129 Gene3D G3DSA:3.30.1460.10 40 127 4.4E-9 T 22-04-2016 HRM2_RS08745 ce1f65827c1328e708d2505025b3d57b 129 SUPERFAMILY SSF69635 41 127 9.03E-11 T 22-04-2016 HRM2_RS15255 94676c6d23b7b2e7efd23609bbba716c 294 Gene3D G3DSA:3.20.20.220 1 287 5.7E-35 T 22-04-2016 IPR029041 FAD-linked oxidoreductase-like HRM2_RS15255 94676c6d23b7b2e7efd23609bbba716c 294 Pfam PF02219 Methylenetetrahydrofolate reductase 3 286 8.6E-24 T 22-04-2016 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 HRM2_RS15255 94676c6d23b7b2e7efd23609bbba716c 294 SUPERFAMILY SSF51730 1 288 1.1E-45 T 22-04-2016 IPR029041 FAD-linked oxidoreductase-like HRM2_RS21980 8ddd95605681f6c8354933195beba6dc 80 Pfam PF05717 IS66 Orf2 like protein 9 79 5.9E-34 T 22-04-2016 IPR008878 Transposase IS66, Orf2 HRM2_RS21980 8ddd95605681f6c8354933195beba6dc 80 PANTHER PTHR36455:SF1 2 79 5.0E-29 T 22-04-2016 HRM2_RS21980 8ddd95605681f6c8354933195beba6dc 80 PANTHER PTHR36455 2 79 5.0E-29 T 22-04-2016 HRM2_RS16640 9a8e62f8fe14b21fc20636ef61b8b66e 88 Pfam PF00589 Phage integrase family 46 73 1.2E-5 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS16640 9a8e62f8fe14b21fc20636ef61b8b66e 88 SUPERFAMILY SSF56349 44 80 2.56E-8 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HRM2_RS16640 9a8e62f8fe14b21fc20636ef61b8b66e 88 Gene3D G3DSA:1.10.443.10 44 81 1.2E-8 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 HRM2_RS20475 f58ff6103a22ca86c64027fddc0fdd23 249 PANTHER PTHR30572 121 248 1.2E-23 T 22-04-2016 HRM2_RS20475 f58ff6103a22ca86c64027fddc0fdd23 249 Pfam PF02687 FtsX-like permease family 123 241 2.4E-14 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 HRM2_RS04735 07c1618e5358832260dd1f3b4a52bb2d 114 Pfam PF02417 Chromate transporter 4 107 4.7E-14 T 22-04-2016 IPR003370 Chromate transporter GO:0015109|GO:0015703 HRM2_RS04735 07c1618e5358832260dd1f3b4a52bb2d 114 PANTHER PTHR33567 3 108 6.6E-15 T 22-04-2016 HRM2_RS04735 07c1618e5358832260dd1f3b4a52bb2d 114 PANTHER PTHR33567:SF1 3 108 6.6E-15 T 22-04-2016 HRM2_RS00860 6f67f7b1eb7fae44766ff1b278b1cb38 84 SUPERFAMILY SSF53850 1 74 6.24E-16 T 22-04-2016 HRM2_RS00860 6f67f7b1eb7fae44766ff1b278b1cb38 84 Pfam PF12849 PBP superfamily domain 1 44 1.7E-6 T 22-04-2016 IPR024370 PBP domain HRM2_RS05345 0de99e8b036e854e21b48c67aafe9363 357 SUPERFAMILY SSF102114 5 262 4.58E-47 T 22-04-2016 HRM2_RS05345 0de99e8b036e854e21b48c67aafe9363 357 Pfam PF16199 Radical_SAM C-terminal domain 187 272 1.0E-16 T 22-04-2016 IPR032432 Radical SAM, C-terminal extension HRM2_RS05345 0de99e8b036e854e21b48c67aafe9363 357 Gene3D G3DSA:3.80.30.20 15 207 6.8E-29 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe HRM2_RS05345 0de99e8b036e854e21b48c67aafe9363 357 Pfam PF04055 Radical SAM superfamily 14 180 1.3E-18 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS05345 0de99e8b036e854e21b48c67aafe9363 357 PANTHER PTHR11135 8 273 3.0E-42 T 22-04-2016 HRM2_RS05345 0de99e8b036e854e21b48c67aafe9363 357 SMART SM00729 8 226 1.4E-31 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS16030 6dd8b0aa521bab462c9dd6dfad116202 134 SUPERFAMILY SSF54593 1 133 1.36E-33 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HRM2_RS16030 6dd8b0aa521bab462c9dd6dfad116202 134 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 117 2.9E-23 T 22-04-2016 HRM2_RS16030 6dd8b0aa521bab462c9dd6dfad116202 134 PANTHER PTHR21366:SF0 1 132 4.9E-35 T 22-04-2016 HRM2_RS16030 6dd8b0aa521bab462c9dd6dfad116202 134 Gene3D G3DSA:3.10.180.10 1 133 2.8E-43 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HRM2_RS16030 6dd8b0aa521bab462c9dd6dfad116202 134 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 5 132 2.4E-48 T 22-04-2016 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384 HRM2_RS16030 6dd8b0aa521bab462c9dd6dfad116202 134 PANTHER PTHR21366 1 132 4.9E-35 T 22-04-2016 HRM2_RS08900 669ed35e7e5933b79de62a73750b257d 262 SUPERFAMILY SSF64438 7 254 1.06E-70 T 22-04-2016 IPR011324 Cytotoxic necrotizing factor-like, catalytic HRM2_RS08900 669ed35e7e5933b79de62a73750b257d 262 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 33 253 1.4E-51 T 22-04-2016 IPR003730 Multi-copper polyphenol oxidoreductase, laccase HRM2_RS08900 669ed35e7e5933b79de62a73750b257d 262 PANTHER PTHR30616 6 256 3.5E-73 T 22-04-2016 HRM2_RS08900 669ed35e7e5933b79de62a73750b257d 262 Gene3D G3DSA:3.60.140.10 8 254 9.2E-72 T 22-04-2016 IPR003730 Multi-copper polyphenol oxidoreductase, laccase HRM2_RS08900 669ed35e7e5933b79de62a73750b257d 262 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 28 252 1.0E-67 T 22-04-2016 IPR003730 Multi-copper polyphenol oxidoreductase, laccase HRM2_RS00800 eb43628eff1e6759451e6a191d8e3aa1 466 Pfam PF13372 Alginate export 43 444 2.9E-43 T 22-04-2016 IPR025388 Alginate export domain UniPathway: UPA00286 HRM2_RS13765 1c81a04eed3a8578b8b6625a48c732a4 459 Gene3D G3DSA:2.70.70.10 333 439 2.9E-35 T 22-04-2016 HRM2_RS13765 1c81a04eed3a8578b8b6625a48c732a4 459 PANTHER PTHR21666 335 449 1.3E-29 T 22-04-2016 HRM2_RS13765 1c81a04eed3a8578b8b6625a48c732a4 459 SUPERFAMILY SSF51261 287 437 3.19E-41 T 22-04-2016 IPR011055 Duplicated hybrid motif HRM2_RS13765 1c81a04eed3a8578b8b6625a48c732a4 459 Pfam PF01551 Peptidase family M23 340 434 9.9E-26 T 22-04-2016 IPR016047 Peptidase M23 HRM2_RS01145 e3e042565cde294f633afda1cf271313 268 Gene3D G3DSA:3.60.40.10 9 207 1.1E-8 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 HRM2_RS01145 e3e042565cde294f633afda1cf271313 268 SUPERFAMILY SSF81606 8 266 1.05E-11 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 HRM2_RS01145 e3e042565cde294f633afda1cf271313 268 Pfam PF13672 Protein phosphatase 2C 12 222 3.6E-9 T 22-04-2016 HRM2_RS23570 0d4b7d2fd062006c64bcbbee3b3bf452 127 Gene3D G3DSA:3.30.450.20 28 125 3.4E-7 T 22-04-2016 HRM2_RS23570 0d4b7d2fd062006c64bcbbee3b3bf452 127 Pfam PF08269 Cache domain 48 124 2.0E-6 T 22-04-2016 IPR004010 Double Cache domain 2 HRM2_RS22955 9cb64a1a3f7ba0b6985e7fb23b49c214 466 PANTHER PTHR22913 112 330 4.2E-45 T 22-04-2016 IPR026107 Hyaluronan synthase/nodulation protein C HRM2_RS22955 9cb64a1a3f7ba0b6985e7fb23b49c214 466 Gene3D G3DSA:3.90.550.10 85 325 1.5E-30 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS22955 9cb64a1a3f7ba0b6985e7fb23b49c214 466 PANTHER PTHR22913:SF12 112 330 4.2E-45 T 22-04-2016 HRM2_RS22955 9cb64a1a3f7ba0b6985e7fb23b49c214 466 SUPERFAMILY SSF53448 77 343 5.06E-44 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS22955 9cb64a1a3f7ba0b6985e7fb23b49c214 466 Pfam PF00535 Glycosyl transferase family 2 86 257 2.2E-28 T 22-04-2016 IPR001173 Glycosyltransferase 2-like HRM2_RS06670 e73106a4f7ad6716ccb95b51f2db9889 344 Gene3D G3DSA:3.40.50.1980 41 162 2.8E-18 T 22-04-2016 HRM2_RS06670 e73106a4f7ad6716ccb95b51f2db9889 344 SUPERFAMILY SSF53807 28 328 3.53E-54 T 22-04-2016 HRM2_RS06670 e73106a4f7ad6716ccb95b51f2db9889 344 PANTHER PTHR30535 3 337 4.3E-54 T 22-04-2016 HRM2_RS06670 e73106a4f7ad6716ccb95b51f2db9889 344 Gene3D G3DSA:3.40.50.1980 163 312 4.2E-22 T 22-04-2016 HRM2_RS06670 e73106a4f7ad6716ccb95b51f2db9889 344 Pfam PF01497 Periplasmic binding protein 44 278 2.6E-27 T 22-04-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 HRM2_RS15840 32bc8630c4e4333d9ff1e2be2a616536 197 PANTHER PTHR36118:SF1 1 195 1.7E-35 T 22-04-2016 HRM2_RS15840 32bc8630c4e4333d9ff1e2be2a616536 197 Hamap MF_00479 Electron transport complex subunit RsxG [rsxG]. 1 183 22.264 T 22-04-2016 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 HRM2_RS15840 32bc8630c4e4333d9ff1e2be2a616536 197 TIGRFAM TIGR01947 rnfG: electron transport complex, RnfABCDGE type, G subunit 9 181 8.2E-38 T 22-04-2016 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 HRM2_RS15840 32bc8630c4e4333d9ff1e2be2a616536 197 PIRSF PIRSF006091 1 192 4.0E-37 T 22-04-2016 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 HRM2_RS15840 32bc8630c4e4333d9ff1e2be2a616536 197 Pfam PF04205 FMN-binding domain 93 177 6.4E-17 T 22-04-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 HRM2_RS15840 32bc8630c4e4333d9ff1e2be2a616536 197 SMART SM00900 93 181 2.6E-17 T 22-04-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 HRM2_RS15840 32bc8630c4e4333d9ff1e2be2a616536 197 PANTHER PTHR36118 1 195 1.7E-35 T 22-04-2016 HRM2_RS25095 a50b4d59d905587197ba157c9c3b3f3e 183 Pfam PF13785 Domain of unknown function (DUF4178) 32 170 4.7E-22 T 22-04-2016 IPR025235 Domain of unknown function DUF4178 HRM2_RS04355 9bc09457e5b889b54df0f0ad648f1158 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 62 3.9E-12 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS04355 9bc09457e5b889b54df0f0ad648f1158 206 Gene3D G3DSA:1.10.357.10 6 204 9.2E-36 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HRM2_RS04355 9bc09457e5b889b54df0f0ad648f1158 206 PANTHER PTHR30055 2 199 3.9E-25 T 22-04-2016 HRM2_RS04355 9bc09457e5b889b54df0f0ad648f1158 206 SUPERFAMILY SSF48498 87 205 5.56E-13 T 22-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal HRM2_RS04355 9bc09457e5b889b54df0f0ad648f1158 206 SUPERFAMILY SSF46689 5 77 3.34E-16 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS04355 9bc09457e5b889b54df0f0ad648f1158 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 2.7E-5 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS04355 9bc09457e5b889b54df0f0ad648f1158 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 2.7E-5 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS19140 c2408e5b8a489c9352fdee1bea4f3a3a 537 Gene3D G3DSA:3.30.450.20 75 206 7.7E-46 T 22-04-2016 HRM2_RS19140 c2408e5b8a489c9352fdee1bea4f3a3a 537 SUPERFAMILY SSF103190 38 207 2.71E-51 T 22-04-2016 IPR029151 Periplasmic sensor domain-like HRM2_RS19140 c2408e5b8a489c9352fdee1bea4f3a3a 537 PANTHER PTHR10799:SF774 301 530 2.7E-49 T 22-04-2016 HRM2_RS19140 c2408e5b8a489c9352fdee1bea4f3a3a 537 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 372 534 2.5E-45 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS19140 c2408e5b8a489c9352fdee1bea4f3a3a 537 SUPERFAMILY SSF55073 379 533 6.98E-52 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS19140 c2408e5b8a489c9352fdee1bea4f3a3a 537 PANTHER PTHR10799 301 530 2.7E-49 T 22-04-2016 HRM2_RS19140 c2408e5b8a489c9352fdee1bea4f3a3a 537 Pfam PF00990 Diguanylate cyclase, GGDEF domain 374 531 3.0E-51 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS19140 c2408e5b8a489c9352fdee1bea4f3a3a 537 SMART SM00267 363 535 4.6E-64 T 22-04-2016 IPR000160 GGDEF domain HRM2_RS19140 c2408e5b8a489c9352fdee1bea4f3a3a 537 Gene3D G3DSA:3.30.70.270 376 534 6.2E-58 T 22-04-2016 HRM2_RS19140 c2408e5b8a489c9352fdee1bea4f3a3a 537 SUPERFAMILY SSF103190 215 284 7.53E-23 T 22-04-2016 IPR029151 Periplasmic sensor domain-like HRM2_RS19140 c2408e5b8a489c9352fdee1bea4f3a3a 537 SUPERFAMILY SSF103190 312 328 7.53E-23 T 22-04-2016 IPR029151 Periplasmic sensor domain-like HRM2_RS19140 c2408e5b8a489c9352fdee1bea4f3a3a 537 Gene3D G3DSA:3.30.450.20 215 330 4.4E-28 T 22-04-2016 HRM2_RS11265 a83460caba3614705568470b8aca2c44 210 SUPERFAMILY SSF52172 69 192 7.12E-14 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS11265 a83460caba3614705568470b8aca2c44 210 Gene3D G3DSA:3.40.50.2300 67 195 2.1E-11 T 22-04-2016 HRM2_RS10275 712c8378067efdcad126e18c2b1082aa 278 Pfam PF07589 PEP-CTERM motif 253 276 7.6E-8 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain HRM2_RS10275 712c8378067efdcad126e18c2b1082aa 278 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 254 277 9.4E-6 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain HRM2_RS10275 712c8378067efdcad126e18c2b1082aa 278 Gene3D G3DSA:3.40.50.410 41 78 1.9E-4 T 22-04-2016 IPR002035 von Willebrand factor, type A HRM2_RS10275 712c8378067efdcad126e18c2b1082aa 278 SUPERFAMILY SSF53300 41 196 8.56E-6 T 22-04-2016 IPR002035 von Willebrand factor, type A HRM2_RS05385 7038c0c82e6d987faf08e238e37564d3 350 Gene3D G3DSA:1.10.1200.80 274 336 2.7E-5 T 22-04-2016 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 HRM2_RS05385 7038c0c82e6d987faf08e238e37564d3 350 PANTHER PTHR11082:SF25 23 339 4.0E-79 T 22-04-2016 HRM2_RS05385 7038c0c82e6d987faf08e238e37564d3 350 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 118 136 - T 22-04-2016 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 HRM2_RS05385 7038c0c82e6d987faf08e238e37564d3 350 Pfam PF01207 Dihydrouridine synthase (Dus) 36 289 4.6E-61 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 HRM2_RS05385 7038c0c82e6d987faf08e238e37564d3 350 PANTHER PTHR11082 23 339 4.0E-79 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 HRM2_RS05385 7038c0c82e6d987faf08e238e37564d3 350 Gene3D G3DSA:3.20.20.70 30 265 1.0E-68 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS05385 7038c0c82e6d987faf08e238e37564d3 350 PIRSF PIRSF006621 23 343 6.1E-71 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 HRM2_RS05385 7038c0c82e6d987faf08e238e37564d3 350 SUPERFAMILY SSF51395 32 335 4.52E-71 T 22-04-2016 HRM2_RS19860 0d998cc3df348c02328a888846b88dc8 176 Gene3D G3DSA:3.10.580.10 106 168 1.5E-11 T 22-04-2016 HRM2_RS19860 0d998cc3df348c02328a888846b88dc8 176 Gene3D G3DSA:3.10.580.10 6 67 1.5E-11 T 22-04-2016 HRM2_RS19860 0d998cc3df348c02328a888846b88dc8 176 Pfam PF00571 CBS domain 5 62 7.4E-5 T 22-04-2016 IPR000644 CBS domain HRM2_RS19860 0d998cc3df348c02328a888846b88dc8 176 SUPERFAMILY SSF54631 1 168 5.18E-13 T 22-04-2016 HRM2_RS00435 8b1155326640f214421b6faa18e17a81 432 Gene3D G3DSA:2.40.50.100 96 131 2.5E-8 T 22-04-2016 HRM2_RS00435 8b1155326640f214421b6faa18e17a81 432 Gene3D G3DSA:2.40.50.100 210 242 2.5E-8 T 22-04-2016 HRM2_RS00435 8b1155326640f214421b6faa18e17a81 432 SUPERFAMILY SSF111369 88 338 3.79E-21 T 22-04-2016 HRM2_RS00435 8b1155326640f214421b6faa18e17a81 432 PANTHER PTHR30469 22 423 3.4E-37 T 22-04-2016 HRM2_RS00435 8b1155326640f214421b6faa18e17a81 432 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 92 263 1.0E-9 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain HRM2_RS00435 8b1155326640f214421b6faa18e17a81 432 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 71 411 1.5E-37 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 HRM2_RS21925 4c129e587bb972812a447ff4af311ba7 354 Pfam PF04986 Putative transposase 142 303 1.2E-33 T 22-04-2016 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 HRM2_RS21925 4c129e587bb972812a447ff4af311ba7 354 PANTHER PTHR37023 2 345 2.9E-37 T 22-04-2016 HRM2_RS21925 4c129e587bb972812a447ff4af311ba7 354 Pfam PF14319 Transposase zinc-binding domain 7 116 2.1E-31 T 22-04-2016 IPR026889 Transposase zinc-binding domain HRM2_RS09780 4c129e587bb972812a447ff4af311ba7 354 Pfam PF04986 Putative transposase 142 303 1.2E-33 T 22-04-2016 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 HRM2_RS09780 4c129e587bb972812a447ff4af311ba7 354 PANTHER PTHR37023 2 345 2.9E-37 T 22-04-2016 HRM2_RS09780 4c129e587bb972812a447ff4af311ba7 354 Pfam PF14319 Transposase zinc-binding domain 7 116 2.1E-31 T 22-04-2016 IPR026889 Transposase zinc-binding domain HRM2_RS06215 4c129e587bb972812a447ff4af311ba7 354 Pfam PF04986 Putative transposase 142 303 1.2E-33 T 22-04-2016 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 HRM2_RS06215 4c129e587bb972812a447ff4af311ba7 354 PANTHER PTHR37023 2 345 2.9E-37 T 22-04-2016 HRM2_RS06215 4c129e587bb972812a447ff4af311ba7 354 Pfam PF14319 Transposase zinc-binding domain 7 116 2.1E-31 T 22-04-2016 IPR026889 Transposase zinc-binding domain HRM2_RS00070 4c129e587bb972812a447ff4af311ba7 354 Pfam PF04986 Putative transposase 142 303 1.2E-33 T 22-04-2016 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 HRM2_RS00070 4c129e587bb972812a447ff4af311ba7 354 PANTHER PTHR37023 2 345 2.9E-37 T 22-04-2016 HRM2_RS00070 4c129e587bb972812a447ff4af311ba7 354 Pfam PF14319 Transposase zinc-binding domain 7 116 2.1E-31 T 22-04-2016 IPR026889 Transposase zinc-binding domain HRM2_RS08305 bf9f829db0a74c612d63906345a01e70 210 Pfam PF04961 Formiminotransferase-cyclodeaminase 7 187 1.2E-63 T 22-04-2016 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00379 HRM2_RS08305 bf9f829db0a74c612d63906345a01e70 210 PANTHER PTHR12234 1 167 7.9E-64 T 22-04-2016 HRM2_RS08305 bf9f829db0a74c612d63906345a01e70 210 SUPERFAMILY SSF101262 3 208 1.96E-59 T 22-04-2016 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00379 HRM2_RS13700 f36f1fc545d701b33f794eecff506715 219 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 5 29 1.7E-8 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site HRM2_RS13700 f36f1fc545d701b33f794eecff506715 219 SUPERFAMILY SSF54523 10 120 2.12E-5 T 22-04-2016 HRM2_RS13700 f36f1fc545d701b33f794eecff506715 219 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 21 5.1E-5 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site HRM2_RS22825 992ff71cec84b63dd123867bd38903a1 282 Gene3D G3DSA:3.40.1160.10 30 281 8.7E-22 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HRM2_RS22825 992ff71cec84b63dd123867bd38903a1 282 SUPERFAMILY SSF53633 47 281 3.27E-24 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HRM2_RS22825 992ff71cec84b63dd123867bd38903a1 282 Pfam PF00696 Amino acid kinase family 47 230 2.8E-16 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HRM2_RS22825 992ff71cec84b63dd123867bd38903a1 282 PIRSF PIRSF039097 6 282 1.8E-119 T 22-04-2016 IPR030669 Molybdenum storage protein subunit alpha/beta GO:0005737|GO:0030151 HRM2_RS04205 7767e9b3102727ecc000df73fce57a12 286 SUPERFAMILY SSF51430 15 270 9.69E-39 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain HRM2_RS04205 7767e9b3102727ecc000df73fce57a12 286 Gene3D G3DSA:3.20.20.100 16 270 6.4E-32 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain HRM2_RS04205 7767e9b3102727ecc000df73fce57a12 286 PRINTS PR00069 Aldo-keto reductase signature 139 156 4.7E-6 T 22-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HRM2_RS04205 7767e9b3102727ecc000df73fce57a12 286 PRINTS PR00069 Aldo-keto reductase signature 102 120 4.7E-6 T 22-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HRM2_RS04205 7767e9b3102727ecc000df73fce57a12 286 PRINTS PR00069 Aldo-keto reductase signature 47 71 4.7E-6 T 22-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HRM2_RS04205 7767e9b3102727ecc000df73fce57a12 286 Pfam PF00248 Aldo/keto reductase family 34 211 1.6E-24 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain HRM2_RS04205 7767e9b3102727ecc000df73fce57a12 286 PANTHER PTHR11732 37 243 5.4E-30 T 22-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta HRM2_RS07660 c897b29f4c29f596edfb10b753405930 152 PANTHER PTHR33387:SF3 5 132 9.7E-26 T 22-04-2016 HRM2_RS07660 c897b29f4c29f596edfb10b753405930 152 Pfam PF06172 Cupin superfamily (DUF985) 3 128 4.7E-37 T 22-04-2016 IPR009327 Cupin domain of unknown function DUF985 HRM2_RS07660 c897b29f4c29f596edfb10b753405930 152 SUPERFAMILY SSF51182 4 133 1.06E-39 T 22-04-2016 IPR011051 RmlC-like cupin domain HRM2_RS07660 c897b29f4c29f596edfb10b753405930 152 PANTHER PTHR33387 5 132 9.7E-26 T 22-04-2016 HRM2_RS07660 c897b29f4c29f596edfb10b753405930 152 Gene3D G3DSA:2.60.120.10 5 132 2.8E-38 T 22-04-2016 IPR014710 RmlC-like jelly roll fold HRM2_RS04785 6b8e28624e226c0b9072a00fb8fd405b 458 PANTHER PTHR33712:SF6 1 449 8.9E-159 T 22-04-2016 HRM2_RS04785 6b8e28624e226c0b9072a00fb8fd405b 458 Gene3D G3DSA:3.40.50.1980 180 286 3.4E-39 T 22-04-2016 HRM2_RS04785 6b8e28624e226c0b9072a00fb8fd405b 458 PANTHER PTHR33712 1 449 8.9E-159 T 22-04-2016 HRM2_RS04785 6b8e28624e226c0b9072a00fb8fd405b 458 Gene3D G3DSA:3.40.50.1980 316 449 7.7E-42 T 22-04-2016 HRM2_RS04785 6b8e28624e226c0b9072a00fb8fd405b 458 TIGRFAM TIGR01283 nifE: nitrogenase MoFe cofactor biosynthesis protein NifE 12 449 1.6E-189 T 22-04-2016 IPR005973 Nitrogenase MoFe cofactor biosynthesis protein NifE GO:0006461|GO:0009399 UniPathway: UPA00782 HRM2_RS04785 6b8e28624e226c0b9072a00fb8fd405b 458 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 40 437 1.0E-109 T 22-04-2016 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 HRM2_RS04785 6b8e28624e226c0b9072a00fb8fd405b 458 SUPERFAMILY SSF53807 19 446 4.58E-132 T 22-04-2016 HRM2_RS04785 6b8e28624e226c0b9072a00fb8fd405b 458 ProSitePatterns PS00699 Nitrogenases component 1 alpha and beta subunits signature 1. 58 65 - T 22-04-2016 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 HRM2_RS04785 6b8e28624e226c0b9072a00fb8fd405b 458 Gene3D G3DSA:3.40.50.1980 40 175 8.3E-51 T 22-04-2016 HRM2_RS18060 dfd5d86c4d22ce13f57e56800377d7f7 386 Pfam PF01594 Domain of unknown function DUF20 32 362 1.4E-39 T 22-04-2016 IPR002549 Transmembrane protein TqsA-like HRM2_RS18060 dfd5d86c4d22ce13f57e56800377d7f7 386 PANTHER PTHR21716:SF13 19 363 3.5E-52 T 22-04-2016 HRM2_RS18060 dfd5d86c4d22ce13f57e56800377d7f7 386 PANTHER PTHR21716 19 363 3.5E-52 T 22-04-2016 IPR002549 Transmembrane protein TqsA-like HRM2_RS05310 d36501b9f78fec750cc10fa52d0ca26b 98 SMART SM00507 27 78 5.2E-9 T 22-04-2016 IPR003615 HNH nuclease HRM2_RS05310 d36501b9f78fec750cc10fa52d0ca26b 98 PANTHER PTHR33877 14 91 8.9E-23 T 22-04-2016 HRM2_RS05310 d36501b9f78fec750cc10fa52d0ca26b 98 Pfam PF14279 HNH endonuclease 38 85 8.8E-16 T 22-04-2016 IPR029471 HNH endonuclease 5 HRM2_RS11485 5887300019da56865aceda26fd875b10 230 SUPERFAMILY SSF51419 1 227 5.37E-75 T 22-04-2016 IPR029066 PLP-binding barrel HRM2_RS11485 5887300019da56865aceda26fd875b10 230 Pfam PF01168 Alanine racemase, N-terminal domain 8 229 2.1E-26 T 22-04-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HRM2_RS11485 5887300019da56865aceda26fd875b10 230 PANTHER PTHR10146 1 229 9.1E-93 T 22-04-2016 IPR011078 Uncharacterised protein family UPF0001 HRM2_RS11485 5887300019da56865aceda26fd875b10 230 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 1 229 9.0E-68 T 22-04-2016 IPR011078 Uncharacterised protein family UPF0001 HRM2_RS11485 5887300019da56865aceda26fd875b10 230 PIRSF PIRSF004848 1 230 3.6E-79 T 22-04-2016 IPR011078 Uncharacterised protein family UPF0001 HRM2_RS11485 5887300019da56865aceda26fd875b10 230 Gene3D G3DSA:3.20.20.10 1 229 5.1E-84 T 22-04-2016 IPR029066 PLP-binding barrel HRM2_RS16405 0619472813ccdc799784091342c7b478 547 Pfam PF03060 Nitronate monooxygenase 89 359 1.2E-9 T 22-04-2016 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 HRM2_RS16405 0619472813ccdc799784091342c7b478 547 PANTHER PTHR10982 195 547 8.2E-197 T 22-04-2016 HRM2_RS16405 0619472813ccdc799784091342c7b478 547 PANTHER PTHR10982 26 165 8.2E-197 T 22-04-2016 HRM2_RS16405 0619472813ccdc799784091342c7b478 547 Gene3D G3DSA:3.20.20.70 249 366 6.9E-18 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS16405 0619472813ccdc799784091342c7b478 547 Gene3D G3DSA:3.20.20.70 90 209 6.9E-18 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS16405 0619472813ccdc799784091342c7b478 547 SUPERFAMILY SSF51412 180 389 1.92E-20 T 22-04-2016 HRM2_RS16405 0619472813ccdc799784091342c7b478 547 SUPERFAMILY SSF51412 90 144 1.92E-20 T 22-04-2016 HRM2_RS16405 0619472813ccdc799784091342c7b478 547 PANTHER PTHR10982:SF11 195 547 8.2E-197 T 22-04-2016 HRM2_RS16405 0619472813ccdc799784091342c7b478 547 PANTHER PTHR10982:SF11 26 165 8.2E-197 T 22-04-2016 HRM2_RS16405 0619472813ccdc799784091342c7b478 547 TIGRFAM TIGR02814 pfaD_fam: PfaD family protein 78 515 2.9E-187 T 22-04-2016 IPR014179 PfaD family protein KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388|UniPathway: UPA01003 HRM2_RS17640 0740fbbb0df0ebc2c91c9201bf2158aa 99 Pfam PF04316 Anti-sigma-28 factor, FlgM 38 90 1.5E-18 T 22-04-2016 IPR031316 Anti-sigma-28 factor FlgM, C-terminal HRM2_RS17640 0740fbbb0df0ebc2c91c9201bf2158aa 99 SUPERFAMILY SSF101498 1 93 6.41E-16 T 22-04-2016 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 HRM2_RS17640 0740fbbb0df0ebc2c91c9201bf2158aa 99 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 3 91 1.3E-19 T 22-04-2016 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 HRM2_RS23960 c86d0a1efabcd95a88e5fc8d43738817 220 Gene3D G3DSA:2.40.50.90 69 169 3.7E-27 T 22-04-2016 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold HRM2_RS23960 c86d0a1efabcd95a88e5fc8d43738817 220 Pfam PF00565 Staphylococcal nuclease homologue 98 200 5.0E-22 T 22-04-2016 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold HRM2_RS23960 c86d0a1efabcd95a88e5fc8d43738817 220 SUPERFAMILY SSF50199 69 203 8.37E-32 T 22-04-2016 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold HRM2_RS23960 c86d0a1efabcd95a88e5fc8d43738817 220 PANTHER PTHR12302:SF0 69 220 1.1E-34 T 22-04-2016 HRM2_RS23960 c86d0a1efabcd95a88e5fc8d43738817 220 PANTHER PTHR12302 69 220 1.1E-34 T 22-04-2016 HRM2_RS23960 c86d0a1efabcd95a88e5fc8d43738817 220 SMART SM00318 64 202 1.3E-22 T 22-04-2016 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold HRM2_RS21940 2d52f15b88b5ab11e04f87f2827b2c34 106 SUPERFAMILY SSF47413 10 79 2.09E-13 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS21940 2d52f15b88b5ab11e04f87f2827b2c34 106 Pfam PF01381 Helix-turn-helix 23 60 6.4E-9 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS21940 2d52f15b88b5ab11e04f87f2827b2c34 106 Gene3D G3DSA:1.10.260.40 14 71 4.3E-12 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS21940 2d52f15b88b5ab11e04f87f2827b2c34 106 SMART SM00530 22 77 5.0E-7 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HRM2_RS23920 c1853c80e2a02b3333bb6a4c83c80f1c 247 SUPERFAMILY SSF56988 61 136 5.75E-8 T 22-04-2016 HRM2_RS23920 c1853c80e2a02b3333bb6a4c83c80f1c 247 Pfam PF07589 PEP-CTERM motif 216 233 8.3E-6 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain HRM2_RS23920 c1853c80e2a02b3333bb6a4c83c80f1c 247 Gene3D G3DSA:3.90.182.10 65 175 3.7E-14 T 22-04-2016 IPR011658 PA14 domain HRM2_RS23920 c1853c80e2a02b3333bb6a4c83c80f1c 247 Pfam PF07691 PA14 domain 63 171 2.8E-7 T 22-04-2016 IPR011658 PA14 domain HRM2_RS23920 c1853c80e2a02b3333bb6a4c83c80f1c 247 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 217 236 3.6E-4 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain HRM2_RS09900 e16c316e6812b9915337c9e0048fa9c3 374 PANTHER PTHR12526 9 374 7.4E-57 T 22-04-2016 HRM2_RS09900 e16c316e6812b9915337c9e0048fa9c3 374 Gene3D G3DSA:3.40.50.2000 167 334 3.0E-24 T 22-04-2016 HRM2_RS09900 e16c316e6812b9915337c9e0048fa9c3 374 Pfam PF13439 Glycosyltransferase Family 4 20 172 3.0E-21 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain HRM2_RS09900 e16c316e6812b9915337c9e0048fa9c3 374 Pfam PF00534 Glycosyl transferases group 1 183 332 2.3E-30 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 HRM2_RS09900 e16c316e6812b9915337c9e0048fa9c3 374 SUPERFAMILY SSF53756 15 373 8.48E-74 T 22-04-2016 HRM2_RS22310 21f3e27f7d4d16c1a0a921d43d18b2da 126 Gene3D G3DSA:1.10.10.10 5 89 6.3E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS22310 21f3e27f7d4d16c1a0a921d43d18b2da 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 71 1.7E-15 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HRM2_RS22310 21f3e27f7d4d16c1a0a921d43d18b2da 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 8 23 1.7E-15 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HRM2_RS22310 21f3e27f7d4d16c1a0a921d43d18b2da 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 41 56 1.7E-15 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HRM2_RS22310 21f3e27f7d4d16c1a0a921d43d18b2da 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 28 39 1.7E-15 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HRM2_RS22310 21f3e27f7d4d16c1a0a921d43d18b2da 126 SUPERFAMILY SSF46785 2 97 7.39E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS22310 21f3e27f7d4d16c1a0a921d43d18b2da 126 PANTHER PTHR33154 7 99 3.6E-17 T 22-04-2016 HRM2_RS22310 21f3e27f7d4d16c1a0a921d43d18b2da 126 Pfam PF12840 Helix-turn-helix domain 7 65 1.9E-9 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS22310 21f3e27f7d4d16c1a0a921d43d18b2da 126 SMART SM00418 6 90 2.7E-18 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HRM2_RS19045 900451946b5c134f09be7e69238a55dd 198 Gene3D G3DSA:3.30.70.240 57 148 3.6E-10 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain HRM2_RS19045 900451946b5c134f09be7e69238a55dd 198 Pfam PF00679 Elongation factor G C-terminus 66 147 3.4E-11 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain HRM2_RS19045 900451946b5c134f09be7e69238a55dd 198 SUPERFAMILY SSF54980 66 148 1.53E-9 T 22-04-2016 IPR009022 Elongation factor G, III-V domain HRM2_RS19910 1719bf9ddd0ab979ed022e51844346e0 119 PANTHER PTHR26402:SF471 4 115 9.8E-33 T 22-04-2016 HRM2_RS19910 1719bf9ddd0ab979ed022e51844346e0 119 PANTHER PTHR26402 4 115 9.8E-33 T 22-04-2016 HRM2_RS19910 1719bf9ddd0ab979ed022e51844346e0 119 SUPERFAMILY SSF52172 1 118 2.85E-33 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS19910 1719bf9ddd0ab979ed022e51844346e0 119 SMART SM00448 4 115 2.7E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS19910 1719bf9ddd0ab979ed022e51844346e0 119 Pfam PF00072 Response regulator receiver domain 6 115 4.4E-24 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS19910 1719bf9ddd0ab979ed022e51844346e0 119 Gene3D G3DSA:3.40.50.2300 4 117 7.7E-33 T 22-04-2016 HRM2_RS23340 561e6eda154efd7771c7f142e0c20060 243 SMART SM00729 18 231 0.0042 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS23340 561e6eda154efd7771c7f142e0c20060 243 Gene3D G3DSA:3.20.20.70 28 228 2.2E-17 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS23340 561e6eda154efd7771c7f142e0c20060 243 SUPERFAMILY SSF102114 28 227 2.62E-20 T 22-04-2016 HRM2_RS23340 561e6eda154efd7771c7f142e0c20060 243 PANTHER PTHR11228:SF25 8 235 9.1E-51 T 22-04-2016 HRM2_RS23340 561e6eda154efd7771c7f142e0c20060 243 PANTHER PTHR11228 8 235 9.1E-51 T 22-04-2016 HRM2_RS23340 561e6eda154efd7771c7f142e0c20060 243 Pfam PF04055 Radical SAM superfamily 26 188 1.5E-11 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS20195 209fc65452905374741e5547be540199 193 SUPERFAMILY SSF52833 42 191 1.05E-37 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS20195 209fc65452905374741e5547be540199 193 PANTHER PTHR10681 41 191 4.6E-32 T 22-04-2016 HRM2_RS20195 209fc65452905374741e5547be540199 193 Gene3D G3DSA:3.40.30.10 42 191 2.0E-43 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS20195 209fc65452905374741e5547be540199 193 Pfam PF00578 AhpC/TSA family 44 169 2.7E-28 T 22-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 HRM2_RS04550 5a16f86bdd160f5f12550cd25acf8517 122 Pfam PF09350 Domain of unknown function (DUF1992) 8 73 1.4E-22 T 22-04-2016 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain HRM2_RS04550 5a16f86bdd160f5f12550cd25acf8517 122 PANTHER PTHR39158 1 122 9.1E-18 T 22-04-2016 HRM2_RS02470 395f055f7a7a281983272ce399278628 360 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 4 343 4.5E-138 T 22-04-2016 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 HRM2_RS02470 395f055f7a7a281983272ce399278628 360 PANTHER PTHR30486 4 356 6.3E-173 T 22-04-2016 HRM2_RS02470 395f055f7a7a281983272ce399278628 360 Gene3D G3DSA:3.40.50.300 101 341 9.4E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02470 395f055f7a7a281983272ce399278628 360 SMART SM00382 123 248 6.8E-4 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS02470 395f055f7a7a281983272ce399278628 360 Pfam PF00437 Type II/IV secretion system protein 93 266 1.6E-40 T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 HRM2_RS02470 395f055f7a7a281983272ce399278628 360 PANTHER PTHR30486:SF6 4 356 6.3E-173 T 22-04-2016 HRM2_RS02470 395f055f7a7a281983272ce399278628 360 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 194 208 - T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 HRM2_RS02470 395f055f7a7a281983272ce399278628 360 SUPERFAMILY SSF52540 4 337 1.03E-65 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS07845 38186e7f898c0b5a1ad9ba6c28dbe35d 339 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 109 312 1.4E-20 T 22-04-2016 HRM2_RS07845 38186e7f898c0b5a1ad9ba6c28dbe35d 339 SUPERFAMILY SSF53850 109 301 3.85E-11 T 22-04-2016 HRM2_RS13030 6c8cbd6ed86e3cd95378f75f8b5289ac 223 Pfam PF08388 Group II intron, maturase-specific domain 94 170 3.5E-21 T 22-04-2016 IPR013597 Group II intron, maturase-specific HRM2_RS15945 b42b66f254009fb2d7079104a7ed7993 286 SUPERFAMILY SSF111321 1 280 9.68E-75 T 22-04-2016 IPR002791 Domain of unknown function DUF89 HRM2_RS15945 b42b66f254009fb2d7079104a7ed7993 286 PIRSF PIRSF006593 1 284 7.2E-81 T 22-04-2016 IPR014444 Uncharacterised conserved protein UCP006593 HRM2_RS15945 b42b66f254009fb2d7079104a7ed7993 286 Pfam PF01937 Protein of unknown function DUF89 3 276 8.6E-44 T 22-04-2016 IPR002791 Domain of unknown function DUF89 HRM2_RS09020 1cbba448761f560491b92bc81a43c37f 391 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 5 362 3.1E-75 T 22-04-2016 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 HRM2_RS09020 1cbba448761f560491b92bc81a43c37f 391 PANTHER PTHR33529 1 390 1.2E-82 T 22-04-2016 HRM2_RS09020 1cbba448761f560491b92bc81a43c37f 391 PANTHER PTHR33529:SF2 1 390 1.2E-82 T 22-04-2016 HRM2_RS09020 1cbba448761f560491b92bc81a43c37f 391 Pfam PF03739 Predicted permease YjgP/YjgQ family 7 362 2.1E-79 T 22-04-2016 IPR005495 Permease LptG/LptF-related GO:0016021 HRM2_RS22920 9adf8b75ad282b974fafc62e44b02ada 145 SUPERFAMILY SSF55785 16 59 5.98E-6 T 22-04-2016 IPR000014 PAS domain HRM2_RS22920 9adf8b75ad282b974fafc62e44b02ada 145 Gene3D G3DSA:3.30.450.20 15 59 2.2E-6 T 22-04-2016 HRM2_RS00240 1d823660fa56139409943a6b42fc06e7 266 Gene3D G3DSA:3.20.20.20 4 259 6.0E-78 T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 HRM2_RS00240 1d823660fa56139409943a6b42fc06e7 266 Pfam PF00809 Pterin binding enzyme 7 228 1.2E-23 T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 HRM2_RS00240 1d823660fa56139409943a6b42fc06e7 266 SUPERFAMILY SSF51717 3 259 1.44E-68 T 22-04-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 HRM2_RS00320 2c93a98772abfde8518cb89c20bbc5a2 202 SUPERFAMILY SSF48498 84 199 3.46E-20 T 22-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal HRM2_RS00320 2c93a98772abfde8518cb89c20bbc5a2 202 PANTHER PTHR30055 1 179 2.0E-28 T 22-04-2016 HRM2_RS00320 2c93a98772abfde8518cb89c20bbc5a2 202 Gene3D G3DSA:1.10.10.60 11 64 1.4E-17 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS00320 2c93a98772abfde8518cb89c20bbc5a2 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 5.0E-11 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS00320 2c93a98772abfde8518cb89c20bbc5a2 202 SUPERFAMILY SSF46689 7 87 2.0E-15 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS00320 2c93a98772abfde8518cb89c20bbc5a2 202 Gene3D G3DSA:1.10.357.10 65 200 2.1E-26 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HRM2_RS00320 2c93a98772abfde8518cb89c20bbc5a2 202 Pfam PF08359 YsiA-like protein, C-terminal region 70 175 3.2E-5 T 22-04-2016 IPR013570 Transcription regulator YsiA, C-terminal HRM2_RS04215 1ada97082c9b97f1b7762e60e7d38cd2 423 PANTHER PTHR37822:SF2 142 383 8.2E-31 T 22-04-2016 HRM2_RS04215 1ada97082c9b97f1b7762e60e7d38cd2 423 PANTHER PTHR37822 142 383 8.2E-31 T 22-04-2016 HRM2_RS00340 24eb9bdec0334fb4a94a4baa4cc1e8a2 493 PANTHER PTHR30203:SF3 1 487 1.9E-64 T 22-04-2016 HRM2_RS00340 24eb9bdec0334fb4a94a4baa4cc1e8a2 493 Gene3D G3DSA:1.20.1600.10 53 486 1.8E-85 T 22-04-2016 HRM2_RS00340 24eb9bdec0334fb4a94a4baa4cc1e8a2 493 Pfam PF02321 Outer membrane efflux protein 310 486 5.7E-21 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS00340 24eb9bdec0334fb4a94a4baa4cc1e8a2 493 Pfam PF02321 Outer membrane efflux protein 87 278 8.9E-19 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS00340 24eb9bdec0334fb4a94a4baa4cc1e8a2 493 SUPERFAMILY SSF56954 6 41 5.1E-94 T 22-04-2016 HRM2_RS00340 24eb9bdec0334fb4a94a4baa4cc1e8a2 493 SUPERFAMILY SSF56954 78 488 5.1E-94 T 22-04-2016 HRM2_RS00340 24eb9bdec0334fb4a94a4baa4cc1e8a2 493 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 21 486 2.3E-107 T 22-04-2016 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 HRM2_RS00340 24eb9bdec0334fb4a94a4baa4cc1e8a2 493 PANTHER PTHR30203 1 487 1.9E-64 T 22-04-2016 HRM2_RS11925 9e903829b3daf38bd7455215bf3fabb9 378 Gene3D G3DSA:1.10.3210.10 25 216 1.4E-42 T 22-04-2016 IPR006674 HD domain HRM2_RS11925 9e903829b3daf38bd7455215bf3fabb9 378 PANTHER PTHR11373 1 167 7.4E-43 T 22-04-2016 HRM2_RS11925 9e903829b3daf38bd7455215bf3fabb9 378 PANTHER PTHR11373:SF25 1 167 7.4E-43 T 22-04-2016 HRM2_RS11925 9e903829b3daf38bd7455215bf3fabb9 378 Pfam PF13286 Phosphohydrolase-associated domain 272 366 5.0E-9 T 22-04-2016 IPR026875 Phosphohydrolase-associated domain HRM2_RS11925 9e903829b3daf38bd7455215bf3fabb9 378 SUPERFAMILY SSF109604 37 169 6.7E-55 T 22-04-2016 HRM2_RS11925 9e903829b3daf38bd7455215bf3fabb9 378 SUPERFAMILY SSF109604 200 369 6.7E-55 T 22-04-2016 HRM2_RS11925 9e903829b3daf38bd7455215bf3fabb9 378 Gene3D G3DSA:1.10.3550.10 262 365 3.1E-4 T 22-04-2016 IPR027432 Deoxyguanosinetriphosphate triphosphohydrolase, C-terminal domain HRM2_RS11925 9e903829b3daf38bd7455215bf3fabb9 378 SMART SM00471 70 229 1.1E-5 T 22-04-2016 IPR003607 HD/PDEase domain HRM2_RS11925 9e903829b3daf38bd7455215bf3fabb9 378 Gene3D G3DSA:1.10.3410.10 217 250 2.5E-6 T 22-04-2016 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain HRM2_RS11925 9e903829b3daf38bd7455215bf3fabb9 378 Pfam PF01966 HD domain 77 218 1.5E-11 T 22-04-2016 IPR006674 HD domain HRM2_RS11330 e62cb471d17f2e46d79a8cc8af5cae65 440 SMART SM00922 137 245 1.5E-20 T 22-04-2016 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal HRM2_RS11330 e62cb471d17f2e46d79a8cc8af5cae65 440 Gene3D G3DSA:3.30.390.10 3 122 1.2E-16 T 22-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HRM2_RS11330 e62cb471d17f2e46d79a8cc8af5cae65 440 PANTHER PTHR13794 1 402 1.0E-57 T 22-04-2016 IPR001354 Mandelate racemase/muconate lactonizing enzyme/methylaspartate ammonia-lyase GO:0003824|GO:0008152 HRM2_RS11330 e62cb471d17f2e46d79a8cc8af5cae65 440 Gene3D G3DSA:3.20.20.120 123 376 3.6E-59 T 22-04-2016 IPR029065 Enolase C-terminal domain-like HRM2_RS11330 e62cb471d17f2e46d79a8cc8af5cae65 440 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 33 119 5.8E-7 T 22-04-2016 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain HRM2_RS11330 e62cb471d17f2e46d79a8cc8af5cae65 440 SUPERFAMILY SSF51604 107 376 1.31E-54 T 22-04-2016 IPR029065 Enolase C-terminal domain-like HRM2_RS11330 e62cb471d17f2e46d79a8cc8af5cae65 440 Pfam PF13378 Enolase C-terminal domain-like 141 370 3.0E-51 T 22-04-2016 IPR029065 Enolase C-terminal domain-like HRM2_RS11330 e62cb471d17f2e46d79a8cc8af5cae65 440 SUPERFAMILY SSF54826 4 119 1.16E-13 T 22-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HRM2_RS15450 aa4516f80fd262789851d2b17b34020c 142 Gene3D G3DSA:3.40.140.10 1 136 9.5E-43 T 22-04-2016 HRM2_RS15450 aa4516f80fd262789851d2b17b34020c 142 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 68 103 - T 22-04-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 HRM2_RS15450 aa4516f80fd262789851d2b17b34020c 142 SUPERFAMILY SSF53927 1 137 3.18E-38 T 22-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 HRM2_RS15450 aa4516f80fd262789851d2b17b34020c 142 PANTHER PTHR11086:SF17 1 133 6.9E-50 T 22-04-2016 HRM2_RS15450 aa4516f80fd262789851d2b17b34020c 142 PIRSF PIRSF006019 1 141 1.4E-48 T 22-04-2016 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210 HRM2_RS15450 aa4516f80fd262789851d2b17b34020c 142 PANTHER PTHR11086 1 133 6.9E-50 T 22-04-2016 IPR015517 Deoxycytidylate deaminase-related HRM2_RS15450 aa4516f80fd262789851d2b17b34020c 142 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 1 114 1.5E-23 T 22-04-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 HRM2_RS06170 61c1667b74cef80331bb652271017974 457 PANTHER PTHR39338:SF2 1 457 1.4E-65 T 22-04-2016 HRM2_RS06170 61c1667b74cef80331bb652271017974 457 Pfam PF05762 VWA domain containing CoxE-like protein 234 446 1.4E-31 T 22-04-2016 IPR008912 Uncharacterised protein family CoxE-like HRM2_RS06170 61c1667b74cef80331bb652271017974 457 PANTHER PTHR39338 1 457 1.4E-65 T 22-04-2016 HRM2_RS02625 4b2564ad9274e36ebc5bceefd0b75809 738 PANTHER PTHR38032 234 572 3.7E-13 T 22-04-2016 HRM2_RS02625 4b2564ad9274e36ebc5bceefd0b75809 738 Pfam PF03961 Protein of unknown function (DUF342) 237 584 4.3E-42 T 22-04-2016 IPR005646 Protein of unknown function DUF342 HRM2_RS05400 f4ce720dbe4d083c2eead4df27065618 155 SMART SM00287 96 152 0.035 T 22-04-2016 IPR003646 SH3-like domain, bacterial-type HRM2_RS05400 f4ce720dbe4d083c2eead4df27065618 155 SMART SM00287 33 95 0.78 T 22-04-2016 IPR003646 SH3-like domain, bacterial-type HRM2_RS05400 f4ce720dbe4d083c2eead4df27065618 155 Pfam PF06347 Bacterial SH3 domain 40 92 3.5E-10 T 22-04-2016 IPR010466 Protein of unknown function DUF1058 HRM2_RS05400 f4ce720dbe4d083c2eead4df27065618 155 Pfam PF06347 Bacterial SH3 domain 102 155 6.4E-16 T 22-04-2016 IPR010466 Protein of unknown function DUF1058 HRM2_RS18015 5d7f389b3d120bc8db401fff1c94fbc8 149 Gene3D G3DSA:2.30.30.40 92 141 1.5E-8 T 22-04-2016 HRM2_RS18015 5d7f389b3d120bc8db401fff1c94fbc8 149 SMART SM00260 10 147 4.7E-25 T 22-04-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HRM2_RS18015 5d7f389b3d120bc8db401fff1c94fbc8 149 SUPERFAMILY SSF50341 13 148 4.19E-33 T 22-04-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HRM2_RS18015 5d7f389b3d120bc8db401fff1c94fbc8 149 Pfam PF01584 CheW-like domain 15 148 8.2E-30 T 22-04-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HRM2_RS18015 5d7f389b3d120bc8db401fff1c94fbc8 149 Gene3D G3DSA:2.40.50.180 53 91 3.3E-8 T 22-04-2016 HRM2_RS18015 5d7f389b3d120bc8db401fff1c94fbc8 149 PANTHER PTHR22617 13 149 8.5E-35 T 22-04-2016 HRM2_RS00455 a61415cd2ce409c1982830641da30516 71 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 41 52 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS00455 a61415cd2ce409c1982830641da30516 71 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS00455 a61415cd2ce409c1982830641da30516 71 Pfam PF14697 4Fe-4S dicluster domain 8 57 3.6E-9 T 22-04-2016 HRM2_RS00455 a61415cd2ce409c1982830641da30516 71 Gene3D G3DSA:3.30.70.20 9 59 1.2E-14 T 22-04-2016 HRM2_RS00455 a61415cd2ce409c1982830641da30516 71 SUPERFAMILY SSF54862 8 61 6.93E-17 T 22-04-2016 HRM2_RS17920 854607d8aa163fe882ebaa5113dc1503 123 PIRSF PIRSF002133 1 123 4.4E-55 T 22-04-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17920 854607d8aa163fe882ebaa5113dc1503 123 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 6.0E-68 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 HRM2_RS17920 854607d8aa163fe882ebaa5113dc1503 123 Pfam PF00164 Ribosomal protein S12/S23 3 123 6.6E-42 T 22-04-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17920 854607d8aa163fe882ebaa5113dc1503 123 Gene3D G3DSA:2.40.50.140 1 123 2.6E-65 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS17920 854607d8aa163fe882ebaa5113dc1503 123 PRINTS PR01034 Ribosomal protein S12 signature 77 94 2.1E-60 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 HRM2_RS17920 854607d8aa163fe882ebaa5113dc1503 123 PRINTS PR01034 Ribosomal protein S12 signature 58 77 2.1E-60 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 HRM2_RS17920 854607d8aa163fe882ebaa5113dc1503 123 PRINTS PR01034 Ribosomal protein S12 signature 110 122 2.1E-60 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 HRM2_RS17920 854607d8aa163fe882ebaa5113dc1503 123 PRINTS PR01034 Ribosomal protein S12 signature 27 42 2.1E-60 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 HRM2_RS17920 854607d8aa163fe882ebaa5113dc1503 123 PRINTS PR01034 Ribosomal protein S12 signature 94 110 2.1E-60 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 HRM2_RS17920 854607d8aa163fe882ebaa5113dc1503 123 PRINTS PR01034 Ribosomal protein S12 signature 42 57 2.1E-60 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 HRM2_RS17920 854607d8aa163fe882ebaa5113dc1503 123 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 40.669 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 HRM2_RS17920 854607d8aa163fe882ebaa5113dc1503 123 SUPERFAMILY SSF50249 2 123 6.51E-52 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS17920 854607d8aa163fe882ebaa5113dc1503 123 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 22-04-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17920 854607d8aa163fe882ebaa5113dc1503 123 PANTHER PTHR11652 1 116 2.0E-70 T 22-04-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HRM2_RS17920 854607d8aa163fe882ebaa5113dc1503 123 PANTHER PTHR11652:SF17 1 116 2.0E-70 T 22-04-2016 HRM2_RS24355 1b42bab1736937baa134a5e50e72de9a 373 Gene3D G3DSA:3.30.750.24 11 94 5.0E-12 T 22-04-2016 IPR002645 STAS domain HRM2_RS24355 1b42bab1736937baa134a5e50e72de9a 373 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 157 369 3.3E-67 T 22-04-2016 IPR003453 ABC transport permease subunit MlaE, Proteobacteria HRM2_RS24355 1b42bab1736937baa134a5e50e72de9a 373 Pfam PF02405 Permease MlaE 162 367 1.3E-70 T 22-04-2016 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 HRM2_RS24355 1b42bab1736937baa134a5e50e72de9a 373 PANTHER PTHR30188:SF3 32 372 3.7E-86 T 22-04-2016 HRM2_RS24355 1b42bab1736937baa134a5e50e72de9a 373 PANTHER PTHR30188 32 372 3.7E-86 T 22-04-2016 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 HRM2_RS24355 1b42bab1736937baa134a5e50e72de9a 373 SUPERFAMILY SSF52091 12 94 1.94E-12 T 22-04-2016 IPR002645 STAS domain HRM2_RS24355 1b42bab1736937baa134a5e50e72de9a 373 Pfam PF13466 STAS domain 16 92 5.4E-12 T 22-04-2016 IPR002645 STAS domain HRM2_RS09040 76129dc7cc8487ef46d4ff937437db77 259 PANTHER PTHR10859 2 108 5.2E-26 T 22-04-2016 HRM2_RS09040 76129dc7cc8487ef46d4ff937437db77 259 PANTHER PTHR10859:SF99 2 108 5.2E-26 T 22-04-2016 HRM2_RS09040 76129dc7cc8487ef46d4ff937437db77 259 Pfam PF00535 Glycosyl transferase family 2 7 108 9.2E-20 T 22-04-2016 IPR001173 Glycosyltransferase 2-like HRM2_RS09040 76129dc7cc8487ef46d4ff937437db77 259 Gene3D G3DSA:3.90.550.10 3 131 5.3E-18 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS09040 76129dc7cc8487ef46d4ff937437db77 259 SUPERFAMILY SSF53448 168 228 1.48E-25 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS09040 76129dc7cc8487ef46d4ff937437db77 259 SUPERFAMILY SSF53448 4 122 1.48E-25 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS03465 a514dad13af8a092fc0a529b9bd5dff0 263 Gene3D G3DSA:3.40.50.300 1 185 4.1E-24 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03465 a514dad13af8a092fc0a529b9bd5dff0 263 Pfam PF13189 Cytidylate kinase-like family 3 168 1.4E-18 T 22-04-2016 IPR026865 Cytidylate kinase-like family MetaCyc: PWY-7205 HRM2_RS15635 a00c8d9af163102bcc464b3b421d918e 274 PANTHER PTHR11938 122 273 1.5E-40 T 22-04-2016 HRM2_RS15635 a00c8d9af163102bcc464b3b421d918e 274 PANTHER PTHR11938 51 89 1.5E-40 T 22-04-2016 HRM2_RS15635 a00c8d9af163102bcc464b3b421d918e 274 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 169 180 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS15635 a00c8d9af163102bcc464b3b421d918e 274 SUPERFAMILY SSF54862 71 273 7.43E-44 T 22-04-2016 HRM2_RS15635 a00c8d9af163102bcc464b3b421d918e 274 Gene3D G3DSA:3.30.70.20 52 82 1.9E-38 T 22-04-2016 HRM2_RS15635 a00c8d9af163102bcc464b3b421d918e 274 Gene3D G3DSA:3.30.70.20 213 273 1.9E-38 T 22-04-2016 HRM2_RS15635 a00c8d9af163102bcc464b3b421d918e 274 Gene3D G3DSA:3.30.70.20 130 169 1.9E-38 T 22-04-2016 HRM2_RS15635 a00c8d9af163102bcc464b3b421d918e 274 Pfam PF13247 4Fe-4S dicluster domain 136 185 7.9E-12 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS15635 a00c8d9af163102bcc464b3b421d918e 274 PANTHER PTHR11938:SF86 122 273 1.5E-40 T 22-04-2016 HRM2_RS15635 a00c8d9af163102bcc464b3b421d918e 274 PANTHER PTHR11938:SF86 51 89 1.5E-40 T 22-04-2016 HRM2_RS15635 a00c8d9af163102bcc464b3b421d918e 274 Gene3D G3DSA:1.10.1060.10 170 195 2.8E-4 T 22-04-2016 HRM2_RS05075 0c34c9d719b437c3979cb633785ef0dc 199 ProSitePatterns PS01265 Tpx family signature. 83 94 - T 22-04-2016 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 HRM2_RS05075 0c34c9d719b437c3979cb633785ef0dc 199 PANTHER PTHR10681 5 165 6.6E-45 T 22-04-2016 HRM2_RS05075 0c34c9d719b437c3979cb633785ef0dc 199 Gene3D G3DSA:3.40.30.10 3 166 1.1E-45 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS05075 0c34c9d719b437c3979cb633785ef0dc 199 PANTHER PTHR10681:SF81 5 165 6.6E-45 T 22-04-2016 HRM2_RS05075 0c34c9d719b437c3979cb633785ef0dc 199 Pfam PF08534 Redoxin 19 162 2.5E-24 T 22-04-2016 IPR013740 Redoxin GO:0016491 HRM2_RS05075 0c34c9d719b437c3979cb633785ef0dc 199 Hamap MF_00269 Probable thiol peroxidase [tpx]. 3 166 35.922 T 22-04-2016 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 HRM2_RS05075 0c34c9d719b437c3979cb633785ef0dc 199 SUPERFAMILY SSF52833 1 162 1.89E-42 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS10545 facb658dfa603b12d5bb35532367587d 253 Pfam PF00005 ABC transporter 20 164 1.0E-25 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS10545 facb658dfa603b12d5bb35532367587d 253 PANTHER PTHR24220:SF358 5 236 6.9E-107 T 22-04-2016 HRM2_RS10545 facb658dfa603b12d5bb35532367587d 253 PANTHER PTHR24220 5 236 6.9E-107 T 22-04-2016 HRM2_RS10545 facb658dfa603b12d5bb35532367587d 253 SMART SM00382 28 213 1.4E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS10545 facb658dfa603b12d5bb35532367587d 253 SUPERFAMILY SSF52540 3 235 7.83E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10545 facb658dfa603b12d5bb35532367587d 253 Gene3D G3DSA:3.40.50.300 3 230 1.3E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10545 facb658dfa603b12d5bb35532367587d 253 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 213 235 8.6E-7 T 22-04-2016 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal HRM2_RS18935 a4a2d2568a14e9f6885070efb825b334 350 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 49 326 4.3E-36 T 22-04-2016 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 HRM2_RS18935 a4a2d2568a14e9f6885070efb825b334 350 PANTHER PTHR33376 1 346 8.5E-48 T 22-04-2016 HRM2_RS15510 912d36b6d99c7ed70f7c009cc60bae27 352 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 2 352 44.47 T 22-04-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 HRM2_RS15510 912d36b6d99c7ed70f7c009cc60bae27 352 Gene3D G3DSA:3.40.1780.10 2 63 1.5E-97 T 22-04-2016 HRM2_RS15510 912d36b6d99c7ed70f7c009cc60bae27 352 Gene3D G3DSA:3.40.1780.10 189 351 1.5E-97 T 22-04-2016 HRM2_RS15510 912d36b6d99c7ed70f7c009cc60bae27 352 Gene3D G3DSA:2.40.10.240 65 149 3.8E-13 T 22-04-2016 HRM2_RS15510 912d36b6d99c7ed70f7c009cc60bae27 352 Pfam PF02547 Queuosine biosynthesis protein 4 351 1.9E-133 T 22-04-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 HRM2_RS15510 912d36b6d99c7ed70f7c009cc60bae27 352 PANTHER PTHR30307:SF0 3 351 6.5E-157 T 22-04-2016 HRM2_RS15510 912d36b6d99c7ed70f7c009cc60bae27 352 SUPERFAMILY SSF111337 3 351 5.1E-128 T 22-04-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 HRM2_RS15510 912d36b6d99c7ed70f7c009cc60bae27 352 PANTHER PTHR30307 3 351 6.5E-157 T 22-04-2016 HRM2_RS15510 912d36b6d99c7ed70f7c009cc60bae27 352 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 3 351 2.9E-123 T 22-04-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 HRM2_RS02830 4e7a9fa89274f96981e6c56a0ad55ed2 405 PANTHER PTHR30572:SF7 1 405 2.7E-118 T 22-04-2016 HRM2_RS02830 4e7a9fa89274f96981e6c56a0ad55ed2 405 Pfam PF12704 MacB-like periplasmic core domain 21 244 4.9E-39 T 22-04-2016 IPR025857 MacB-like periplasmic core domain HRM2_RS02830 4e7a9fa89274f96981e6c56a0ad55ed2 405 Pfam PF02687 FtsX-like permease family 286 398 2.0E-21 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 HRM2_RS02830 4e7a9fa89274f96981e6c56a0ad55ed2 405 PANTHER PTHR30572 1 405 2.7E-118 T 22-04-2016 HRM2_RS01660 52cb92230894e019120e935c5b864910 98 PANTHER PTHR10314:SF3 5 83 5.8E-19 T 22-04-2016 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 HRM2_RS01660 52cb92230894e019120e935c5b864910 98 Gene3D G3DSA:3.40.50.1100 7 90 2.3E-26 T 22-04-2016 HRM2_RS01660 52cb92230894e019120e935c5b864910 98 SUPERFAMILY SSF53686 2 87 9.56E-25 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HRM2_RS01660 52cb92230894e019120e935c5b864910 98 PANTHER PTHR10314 5 83 5.8E-19 T 22-04-2016 HRM2_RS09285 94a1f247297909e929de9966df537c5d 310 Pfam PF09991 Predicted membrane protein (DUF2232) 6 293 3.0E-55 T 22-04-2016 IPR018710 Protein of unknown function DUF2232 HRM2_RS24910 00b898c25f48a719a09ee806a43fb510 1267 SUPERFAMILY SSF53474 454 498 2.96E-8 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS24910 00b898c25f48a719a09ee806a43fb510 1267 SUPERFAMILY SSF53474 232 356 2.96E-8 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS24910 00b898c25f48a719a09ee806a43fb510 1267 SUPERFAMILY SSF53474 390 421 2.96E-8 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS24910 00b898c25f48a719a09ee806a43fb510 1267 Gene3D G3DSA:3.40.50.1820 235 355 7.8E-10 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS24910 00b898c25f48a719a09ee806a43fb510 1267 Gene3D G3DSA:3.40.50.1820 483 534 7.8E-10 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS24910 00b898c25f48a719a09ee806a43fb510 1267 Gene3D G3DSA:3.40.50.1820 434 449 7.8E-10 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS24910 00b898c25f48a719a09ee806a43fb510 1267 Pfam PF12770 CHAT domain 1077 1257 6.5E-18 T 22-04-2016 IPR024983 CHAT domain HRM2_RS03685 154001fa1e2cdba150f65681620b0f88 939 Gene3D G3DSA:3.40.50.1460 671 929 1.1E-48 T 22-04-2016 IPR029030 Caspase-like domain HRM2_RS03685 154001fa1e2cdba150f65681620b0f88 939 SUPERFAMILY SSF52129 639 820 1.62E-8 T 22-04-2016 IPR029030 Caspase-like domain HRM2_RS03685 154001fa1e2cdba150f65681620b0f88 939 SUPERFAMILY SSF52129 856 912 1.62E-8 T 22-04-2016 IPR029030 Caspase-like domain HRM2_RS03685 154001fa1e2cdba150f65681620b0f88 939 PANTHER PTHR31773 673 809 6.0E-32 T 22-04-2016 HRM2_RS03685 154001fa1e2cdba150f65681620b0f88 939 SMART SM00701 5 143 0.0019 T 22-04-2016 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 HRM2_RS03685 154001fa1e2cdba150f65681620b0f88 939 SUPERFAMILY SSF55846 18 159 2.22E-28 T 22-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 HRM2_RS03685 154001fa1e2cdba150f65681620b0f88 939 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 24 156 5.6E-5 T 22-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 HRM2_RS03685 154001fa1e2cdba150f65681620b0f88 939 Gene3D G3DSA:3.40.80.10 20 159 4.6E-24 T 22-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 HRM2_RS03685 154001fa1e2cdba150f65681620b0f88 939 Pfam PF00656 Caspase domain 673 925 1.7E-27 T 22-04-2016 HRM2_RS18240 8c94f66ae994d18e9ef58a8a453d5faa 166 Pfam PF05130 FlgN protein 5 135 3.8E-12 T 22-04-2016 IPR007809 FlgN-like protein GO:0005515|GO:0044780 HRM2_RS18240 8c94f66ae994d18e9ef58a8a453d5faa 166 Gene3D G3DSA:1.20.58.300 6 71 5.4E-7 T 22-04-2016 IPR007809 FlgN-like protein GO:0005515|GO:0044780 HRM2_RS18240 8c94f66ae994d18e9ef58a8a453d5faa 166 SUPERFAMILY SSF140566 5 134 3.92E-10 T 22-04-2016 IPR007809 FlgN-like protein GO:0005515|GO:0044780 HRM2_RS14225 16da8227c85330e57cbfa3a46491df54 170 Gene3D G3DSA:2.30.110.10 26 138 7.1E-7 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 HRM2_RS14225 16da8227c85330e57cbfa3a46491df54 170 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 25 108 2.7E-5 T 22-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 HRM2_RS14225 16da8227c85330e57cbfa3a46491df54 170 SUPERFAMILY SSF50475 25 164 2.62E-11 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 HRM2_RS15410 8536c8ef63e3a5b5acdc49bca8d775d1 71 Gene3D G3DSA:2.60.40.360 29 70 3.2E-5 T 22-04-2016 IPR008962 PapD-like HRM2_RS10625 025675200957d34adcd47cc46dff8aea 607 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 384 529 2.1E-22 T 22-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HRM2_RS10625 025675200957d34adcd47cc46dff8aea 607 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 21 186 1.4E-10 T 22-04-2016 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 HRM2_RS10625 025675200957d34adcd47cc46dff8aea 607 Pfam PF13187 4Fe-4S dicluster domain 556 602 1.5E-6 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS10625 025675200957d34adcd47cc46dff8aea 607 SUPERFAMILY SSF52518 6 186 6.28E-48 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS10625 025675200957d34adcd47cc46dff8aea 607 Gene3D G3DSA:3.40.50.970 353 550 6.4E-26 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS10625 025675200957d34adcd47cc46dff8aea 607 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 588 599 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS10625 025675200957d34adcd47cc46dff8aea 607 PANTHER PTHR18968:SF91 283 599 7.3E-68 T 22-04-2016 HRM2_RS10625 025675200957d34adcd47cc46dff8aea 607 PANTHER PTHR18968 283 599 7.3E-68 T 22-04-2016 HRM2_RS10625 025675200957d34adcd47cc46dff8aea 607 Gene3D G3DSA:3.40.50.970 3 184 1.3E-48 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS10625 025675200957d34adcd47cc46dff8aea 607 SUPERFAMILY SSF54862 551 606 2.33E-11 T 22-04-2016 HRM2_RS10625 025675200957d34adcd47cc46dff8aea 607 PIRSF PIRSF006439 1 607 9.8E-208 T 22-04-2016 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 HRM2_RS10625 025675200957d34adcd47cc46dff8aea 607 SUPERFAMILY SSF52518 353 551 7.36E-31 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS10625 025675200957d34adcd47cc46dff8aea 607 Gene3D G3DSA:3.30.70.20 554 604 4.7E-12 T 22-04-2016 HRM2_RS09775 27e642c51a6d68e1fc63f4c01398f60d 477 SUPERFAMILY SSF56935 240 433 6.72E-6 T 22-04-2016 HRM2_RS09775 27e642c51a6d68e1fc63f4c01398f60d 477 SUPERFAMILY SSF56935 99 212 6.72E-6 T 22-04-2016 HRM2_RS09775 27e642c51a6d68e1fc63f4c01398f60d 477 Pfam PF10082 Putative beta-barrel porin 2 339 453 3.1E-8 T 22-04-2016 IPR018759 Putative beta-barrel porin 2 HRM2_RS09775 27e642c51a6d68e1fc63f4c01398f60d 477 Gene3D G3DSA:2.40.170.20 101 295 3.9E-5 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 HRM2_RS12875 d25fce15301d59fcf6f6e6568e006cc9 341 SUPERFAMILY SSF159501 33 314 1.73E-52 T 22-04-2016 HRM2_RS12875 d25fce15301d59fcf6f6e6568e006cc9 341 Pfam PF04187 Haem-binding uptake, Tiki superfamily, ChaN 51 268 1.1E-49 T 22-04-2016 IPR007314 Haem-binding uptake, Tiki superfamily, ChaN HRM2_RS09185 1c1c82cadcb4118215c707b6ee4a27f8 179 Pfam PF14385 Domain of unknown function (DUF4416) 9 168 4.4E-67 T 22-04-2016 IPR025529 Protein of unknown function DUF4416 HRM2_RS10825 cb8f3e091b385df1744b4d638be5c9e9 216 Pfam PF00717 Peptidase S24-like 129 194 1.3E-10 T 22-04-2016 IPR019759 Peptidase S24/S26A/S26B HRM2_RS10825 cb8f3e091b385df1744b4d638be5c9e9 216 Gene3D G3DSA:1.10.260.40 19 58 3.3E-4 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS10825 cb8f3e091b385df1744b4d638be5c9e9 216 PANTHER PTHR40661 2 210 2.2E-16 T 22-04-2016 HRM2_RS10825 cb8f3e091b385df1744b4d638be5c9e9 216 Gene3D G3DSA:2.10.109.10 85 215 2.0E-28 T 22-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain HRM2_RS10825 cb8f3e091b385df1744b4d638be5c9e9 216 Pfam PF07022 Bacteriophage CI repressor helix-turn-helix domain 7 69 3.5E-7 T 22-04-2016 IPR010744 Bacteriophage CI repressor GO:0003677|GO:0045892 HRM2_RS10825 cb8f3e091b385df1744b4d638be5c9e9 216 SUPERFAMILY SSF51306 83 213 9.29E-25 T 22-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C HRM2_RS02950 a0fc24084b63a67e3cdac5f539956797 350 Pfam PF00793 DAHP synthetase I family 43 337 4.4E-85 T 22-04-2016 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 HRM2_RS02950 a0fc24084b63a67e3cdac5f539956797 350 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 6 346 6.3E-138 T 22-04-2016 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 HRM2_RS02950 a0fc24084b63a67e3cdac5f539956797 350 PANTHER PTHR21225 1 347 9.1E-200 T 22-04-2016 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 HRM2_RS02950 a0fc24084b63a67e3cdac5f539956797 350 Gene3D G3DSA:3.20.20.70 9 348 1.6E-139 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS02950 a0fc24084b63a67e3cdac5f539956797 350 SUPERFAMILY SSF51569 6 346 1.78E-126 T 22-04-2016 HRM2_RS02950 a0fc24084b63a67e3cdac5f539956797 350 PIRSF PIRSF001361 1 350 1.3E-150 T 22-04-2016 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 HRM2_RS13290 0f8b272b5a749875d3dc5237abf86dc1 544 SUPERFAMILY SSF52540 5 271 6.25E-124 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13290 0f8b272b5a749875d3dc5237abf86dc1 544 Gene3D G3DSA:3.40.50.300 3 286 3.3E-134 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13290 0f8b272b5a749875d3dc5237abf86dc1 544 TIGRFAM TIGR00337 PyrG: CTP synthase 4 539 9.5E-253 T 22-04-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 HRM2_RS13290 0f8b272b5a749875d3dc5237abf86dc1 544 Hamap MF_01227 CTP synthase [pyrG]. 5 544 52.515 T 22-04-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 HRM2_RS13290 0f8b272b5a749875d3dc5237abf86dc1 544 Pfam PF00117 Glutamine amidotransferase class-I 303 539 4.7E-55 T 22-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 HRM2_RS13290 0f8b272b5a749875d3dc5237abf86dc1 544 Pfam PF06418 CTP synthase N-terminus 6 268 1.7E-126 T 22-04-2016 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 HRM2_RS13290 0f8b272b5a749875d3dc5237abf86dc1 544 Gene3D G3DSA:3.40.50.880 290 543 4.8E-98 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS13290 0f8b272b5a749875d3dc5237abf86dc1 544 SUPERFAMILY SSF52317 290 543 3.88E-82 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like HRM2_RS13290 0f8b272b5a749875d3dc5237abf86dc1 544 PANTHER PTHR11550 1 541 0.0 T 22-04-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 HRM2_RS02675 1410f04c2a9e5e8e572fd952cd362240 364 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 157 252 1.9E-18 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HRM2_RS02675 1410f04c2a9e5e8e572fd952cd362240 364 SUPERFAMILY SSF161098 155 356 3.92E-39 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS02675 1410f04c2a9e5e8e572fd952cd362240 364 PANTHER PTHR30085 65 363 6.8E-123 T 22-04-2016 HRM2_RS02675 1410f04c2a9e5e8e572fd952cd362240 364 Gene3D G3DSA:1.10.3720.10 153 361 1.3E-43 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS02675 1410f04c2a9e5e8e572fd952cd362240 364 PANTHER PTHR30085:SF3 65 363 6.8E-123 T 22-04-2016 HRM2_RS02675 1410f04c2a9e5e8e572fd952cd362240 364 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 174 359 3.0E-22 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS02510 2cae17ff23cd392995af6e8425455f37 362 SUPERFAMILY SSF82829 222 330 1.02E-13 T 22-04-2016 HRM2_RS02510 2cae17ff23cd392995af6e8425455f37 362 PANTHER PTHR11807:SF2 10 246 1.7E-64 T 22-04-2016 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 HRM2_RS02510 2cae17ff23cd392995af6e8425455f37 362 Pfam PF01171 PP-loop family 30 211 1.6E-49 T 22-04-2016 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal HRM2_RS02510 2cae17ff23cd392995af6e8425455f37 362 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 20 325 22.925 T 22-04-2016 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 HRM2_RS02510 2cae17ff23cd392995af6e8425455f37 362 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 30 214 2.3E-50 T 22-04-2016 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 HRM2_RS02510 2cae17ff23cd392995af6e8425455f37 362 PANTHER PTHR11807 10 246 1.7E-64 T 22-04-2016 HRM2_RS02510 2cae17ff23cd392995af6e8425455f37 362 Gene3D G3DSA:3.40.50.620 24 187 1.4E-16 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS02510 2cae17ff23cd392995af6e8425455f37 362 SUPERFAMILY SSF52402 16 242 3.94E-53 T 22-04-2016 HRM2_RS03305 d74228856aa7bea302df1a22b73dafef 470 PANTHER PTHR20852 160 470 5.4E-237 T 22-04-2016 HRM2_RS03305 d74228856aa7bea302df1a22b73dafef 470 PANTHER PTHR20852 1 138 5.4E-237 T 22-04-2016 HRM2_RS03305 d74228856aa7bea302df1a22b73dafef 470 Gene3D G3DSA:3.10.20.70 3 105 6.6E-35 T 22-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HRM2_RS03305 d74228856aa7bea302df1a22b73dafef 470 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 14 95 1.5E-25 T 22-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HRM2_RS03305 d74228856aa7bea302df1a22b73dafef 470 PANTHER PTHR20852:SF15 160 470 5.4E-237 T 22-04-2016 HRM2_RS03305 d74228856aa7bea302df1a22b73dafef 470 PANTHER PTHR20852:SF15 1 138 5.4E-237 T 22-04-2016 HRM2_RS03305 d74228856aa7bea302df1a22b73dafef 470 Pfam PF00120 Glutamine synthetase, catalytic domain 103 466 1.2E-128 T 22-04-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HRM2_RS03305 d74228856aa7bea302df1a22b73dafef 470 Gene3D G3DSA:3.30.590.10 106 450 1.3E-132 T 22-04-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 HRM2_RS03305 d74228856aa7bea302df1a22b73dafef 470 SUPERFAMILY SSF54368 3 101 2.22E-31 T 22-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HRM2_RS03305 d74228856aa7bea302df1a22b73dafef 470 SMART SM01230 102 379 1.2E-143 T 22-04-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HRM2_RS03305 d74228856aa7bea302df1a22b73dafef 470 SUPERFAMILY SSF55931 103 469 9.81E-131 T 22-04-2016 HRM2_RS03305 d74228856aa7bea302df1a22b73dafef 470 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 5 469 6.8E-195 T 22-04-2016 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HRM2_RS03305 d74228856aa7bea302df1a22b73dafef 470 ProSitePatterns PS00180 Glutamine synthetase signature 1. 50 68 - T 22-04-2016 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HRM2_RS03305 d74228856aa7bea302df1a22b73dafef 470 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 386 398 - T 22-04-2016 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HRM2_RS03305 d74228856aa7bea302df1a22b73dafef 470 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 258 273 - T 22-04-2016 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HRM2_RS12265 338c7b2722d2ba1919ed77d8e29dce3d 179 Gene3D G3DSA:1.10.3210.10 20 119 2.0E-8 T 22-04-2016 IPR006674 HD domain HRM2_RS12265 338c7b2722d2ba1919ed77d8e29dce3d 179 SUPERFAMILY SSF109604 16 129 2.9E-14 T 22-04-2016 HRM2_RS12265 338c7b2722d2ba1919ed77d8e29dce3d 179 TIGRFAM TIGR00277 HDIG: HDIG domain 21 98 8.9E-11 T 22-04-2016 IPR006675 HDIG domain HRM2_RS12265 338c7b2722d2ba1919ed77d8e29dce3d 179 SMART SM00471 18 152 6.3E-4 T 22-04-2016 IPR003607 HD/PDEase domain HRM2_RS12265 338c7b2722d2ba1919ed77d8e29dce3d 179 Pfam PF01966 HD domain 23 119 4.8E-9 T 22-04-2016 IPR006674 HD domain HRM2_RS16530 ff1e1dfd21ad933d1fc7cf56a3ba03e0 590 PANTHER PTHR11814 1 569 3.7E-162 T 22-04-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Reactome: REACT_15518 HRM2_RS16530 ff1e1dfd21ad933d1fc7cf56a3ba03e0 590 SUPERFAMILY SSF52091 441 548 2.16E-16 T 22-04-2016 IPR002645 STAS domain HRM2_RS16530 ff1e1dfd21ad933d1fc7cf56a3ba03e0 590 Pfam PF00916 Sulfate permease family 19 386 1.8E-88 T 22-04-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 HRM2_RS16530 ff1e1dfd21ad933d1fc7cf56a3ba03e0 590 Pfam PF01740 STAS domain 443 542 9.7E-10 T 22-04-2016 IPR002645 STAS domain HRM2_RS16530 ff1e1dfd21ad933d1fc7cf56a3ba03e0 590 PANTHER PTHR11814:SF71 1 569 3.7E-162 T 22-04-2016 HRM2_RS16530 ff1e1dfd21ad933d1fc7cf56a3ba03e0 590 Gene3D G3DSA:3.30.750.24 442 549 8.7E-14 T 22-04-2016 IPR002645 STAS domain HRM2_RS01025 8f077504e02361e0a74d78fc97207e4f 73 Gene3D G3DSA:3.40.1690.10 2 44 1.2E-7 T 22-04-2016 IPR029025 Type III secretion system substrate exporter, C-terminal HRM2_RS01025 8f077504e02361e0a74d78fc97207e4f 73 SUPERFAMILY SSF160544 2 45 1.07E-7 T 22-04-2016 IPR029025 Type III secretion system substrate exporter, C-terminal HRM2_RS01025 8f077504e02361e0a74d78fc97207e4f 73 Pfam PF01312 FlhB HrpN YscU SpaS Family 2 40 7.0E-6 T 22-04-2016 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HRM2_RS07450 c165d69cded3441c65c13918664dbcc0 291 SMART SM00729 15 233 9.3E-15 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS07450 c165d69cded3441c65c13918664dbcc0 291 SUPERFAMILY SSF102114 11 235 2.09E-27 T 22-04-2016 HRM2_RS07450 c165d69cded3441c65c13918664dbcc0 291 PANTHER PTHR11918 8 275 4.9E-36 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein HRM2_RS07450 c165d69cded3441c65c13918664dbcc0 291 Pfam PF04055 Radical SAM superfamily 21 174 2.7E-15 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS07450 c165d69cded3441c65c13918664dbcc0 291 Gene3D G3DSA:3.80.30.20 17 173 1.2E-19 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe HRM2_RS07450 c165d69cded3441c65c13918664dbcc0 291 PANTHER PTHR11918:SF47 8 275 4.9E-36 T 22-04-2016 HRM2_RS17195 debd6adf14f115edeafd1f5e960be7ca 77 Gene3D G3DSA:3.40.50.1000 20 51 5.5E-5 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS08970 b7732b166fe81491b6e9c3c9a93fdd95 214 PANTHER PTHR11807:SF17 1 208 6.3E-48 T 22-04-2016 HRM2_RS08970 b7732b166fe81491b6e9c3c9a93fdd95 214 TIGRFAM TIGR00268 TIGR00268: TIGR00268 family protein 2 201 1.0E-55 T 22-04-2016 IPR005232 Conserved hypothetical protein CHP00268 HRM2_RS08970 b7732b166fe81491b6e9c3c9a93fdd95 214 SUPERFAMILY SSF52402 2 156 1.82E-22 T 22-04-2016 HRM2_RS08970 b7732b166fe81491b6e9c3c9a93fdd95 214 Gene3D G3DSA:3.40.50.620 1 104 2.6E-16 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS08970 b7732b166fe81491b6e9c3c9a93fdd95 214 PANTHER PTHR11807 1 208 6.3E-48 T 22-04-2016 HRM2_RS06555 218e22b7b5b085101842e980c37e790e 191 Pfam PF14065 Protein of unknown function (DUF4255) 9 182 3.2E-32 T 22-04-2016 IPR025351 Protein of unknown function DUF4255 HRM2_RS04415 c64b172820d84be5cb305fccbab7bfcf 353 PANTHER PTHR10426:SF4 11 353 3.0E-146 T 22-04-2016 HRM2_RS04415 c64b172820d84be5cb305fccbab7bfcf 353 Gene3D G3DSA:2.120.10.30 11 350 2.2E-60 T 22-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like HRM2_RS04415 c64b172820d84be5cb305fccbab7bfcf 353 SUPERFAMILY SSF63829 300 352 1.37E-52 T 22-04-2016 HRM2_RS04415 c64b172820d84be5cb305fccbab7bfcf 353 SUPERFAMILY SSF63829 29 267 1.37E-52 T 22-04-2016 HRM2_RS04415 c64b172820d84be5cb305fccbab7bfcf 353 Pfam PF03088 Strictosidine synthase 147 234 1.3E-29 T 22-04-2016 IPR018119 Strictosidine synthase, conserved region GO:0009058|GO:0016844 HRM2_RS04415 c64b172820d84be5cb305fccbab7bfcf 353 PANTHER PTHR10426 11 353 3.0E-146 T 22-04-2016 IPR004141 Strictosidine synthase GO:0009058|GO:0016844 HRM2_RS16740 3f173721b823a00e3cdae78a42c077de 405 Gene3D G3DSA:1.20.1250.20 234 398 5.3E-12 T 22-04-2016 HRM2_RS16740 3f173721b823a00e3cdae78a42c077de 405 Gene3D G3DSA:1.20.1250.20 28 205 1.2E-23 T 22-04-2016 HRM2_RS16740 3f173721b823a00e3cdae78a42c077de 405 PANTHER PTHR23501:SF79 23 399 4.4E-130 T 22-04-2016 HRM2_RS16740 3f173721b823a00e3cdae78a42c077de 405 SUPERFAMILY SSF103473 5 398 5.23E-52 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS16740 3f173721b823a00e3cdae78a42c077de 405 PANTHER PTHR23501 23 399 4.4E-130 T 22-04-2016 HRM2_RS16740 3f173721b823a00e3cdae78a42c077de 405 Pfam PF07690 Major Facilitator Superfamily 37 310 9.9E-26 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS20480 168d6ea0dbce343ea1eb433bbe3cd0ba 421 PANTHER PTHR21015 125 416 7.8E-54 T 22-04-2016 HRM2_RS20480 168d6ea0dbce343ea1eb433bbe3cd0ba 421 PANTHER PTHR21015 9 109 7.8E-54 T 22-04-2016 HRM2_RS20480 168d6ea0dbce343ea1eb433bbe3cd0ba 421 PANTHER PTHR21015:SF23 125 416 7.8E-54 T 22-04-2016 IPR016683 Glycosyl transferase, family 28, RedA, predicted HRM2_RS20480 168d6ea0dbce343ea1eb433bbe3cd0ba 421 PANTHER PTHR21015:SF23 9 109 7.8E-54 T 22-04-2016 IPR016683 Glycosyl transferase, family 28, RedA, predicted HRM2_RS20480 168d6ea0dbce343ea1eb433bbe3cd0ba 421 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 258 372 2.8E-11 T 22-04-2016 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HRM2_RS20480 168d6ea0dbce343ea1eb433bbe3cd0ba 421 Gene3D G3DSA:3.40.50.2000 192 378 1.4E-24 T 22-04-2016 HRM2_RS20480 168d6ea0dbce343ea1eb433bbe3cd0ba 421 SUPERFAMILY SSF53756 9 380 5.76E-17 T 22-04-2016 HRM2_RS03545 fc2cd00ec898e08f01cd3f53d1fd466e 63 Gene3D G3DSA:3.50.30.50 8 56 2.6E-4 T 22-04-2016 HRM2_RS03545 fc2cd00ec898e08f01cd3f53d1fd466e 63 SUPERFAMILY SSF102198 5 48 2.49E-5 T 22-04-2016 HRM2_RS05845 5da25b572764744c093a39a69bbd75ef 229 PANTHER PTHR32071 1 142 5.3E-34 T 22-04-2016 HRM2_RS05845 5da25b572764744c093a39a69bbd75ef 229 PANTHER PTHR32071:SF18 1 142 5.3E-34 T 22-04-2016 HRM2_RS05845 5da25b572764744c093a39a69bbd75ef 229 Pfam PF00072 Response regulator receiver domain 18 127 4.2E-27 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS05845 5da25b572764744c093a39a69bbd75ef 229 Gene3D G3DSA:3.40.50.2300 16 163 3.5E-33 T 22-04-2016 HRM2_RS05845 5da25b572764744c093a39a69bbd75ef 229 SMART SM00448 16 127 3.5E-29 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS05845 5da25b572764744c093a39a69bbd75ef 229 SUPERFAMILY SSF52172 16 131 2.42E-33 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS25615 4be51e2d99b89a66e74de64b6c159591 601 Pfam PF13271 Domain of unknown function (DUF4062) 6 87 5.5E-28 T 22-04-2016 IPR025139 Domain of unknown function DUF4062 HRM2_RS09135 50ea0f8dfa8c26229a0112134f5df235 254 Pfam PF00535 Glycosyl transferase family 2 10 173 3.8E-25 T 22-04-2016 IPR001173 Glycosyltransferase 2-like HRM2_RS09135 50ea0f8dfa8c26229a0112134f5df235 254 PANTHER PTHR10859 2 242 5.6E-69 T 22-04-2016 HRM2_RS09135 50ea0f8dfa8c26229a0112134f5df235 254 SUPERFAMILY SSF53448 5 237 2.25E-41 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS09135 50ea0f8dfa8c26229a0112134f5df235 254 Gene3D G3DSA:3.90.550.10 7 181 1.4E-27 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS09135 50ea0f8dfa8c26229a0112134f5df235 254 PANTHER PTHR10859:SF49 2 242 5.6E-69 T 22-04-2016 HRM2_RS15515 2937c79d0a55896c80fed19d7c3e922e 63 Pfam PF09838 Uncharacterized protein conserved in bacteria (DUF2065) 4 58 5.2E-21 T 22-04-2016 IPR019201 Protein of unknown function DUF2065 HRM2_RS04840 14743dc8f18dcf86b3a7033d4b767d07 256 Pfam PF07357 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) 1 252 1.6E-105 T 22-04-2016 IPR009953 Dinitrogenase reductase ADP-ribosyltransferase HRM2_RS24045 bb5d1551cde5649978a1517bda3cf217 298 PANTHER PTHR31290 36 298 1.5E-56 T 22-04-2016 HRM2_RS24045 bb5d1551cde5649978a1517bda3cf217 298 Pfam PF03851 UV-endonuclease UvdE 20 261 1.0E-62 T 22-04-2016 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 HRM2_RS24045 bb5d1551cde5649978a1517bda3cf217 298 Gene3D G3DSA:3.20.20.150 117 253 1.4E-7 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain HRM2_RS24045 bb5d1551cde5649978a1517bda3cf217 298 SUPERFAMILY SSF51658 77 280 1.37E-16 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain HRM2_RS24045 bb5d1551cde5649978a1517bda3cf217 298 TIGRFAM TIGR00629 uvde: UV damage endonuclease UvdE 12 296 1.3E-57 T 22-04-2016 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 HRM2_RS01360 a7c6d02fac62f6d45009448187ea6d96 302 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 286 1.5E-46 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 HRM2_RS01360 a7c6d02fac62f6d45009448187ea6d96 302 PANTHER PTHR11795:SF371 1 302 1.6E-117 T 22-04-2016 HRM2_RS01360 a7c6d02fac62f6d45009448187ea6d96 302 PANTHER PTHR11795 1 302 1.6E-117 T 22-04-2016 HRM2_RS20250 b7a3e21831c242448e7adb02269086e5 198 Gene3D G3DSA:2.20.28.10 1 36 1.3E-18 T 22-04-2016 IPR004039 Rubredoxin-type fold HRM2_RS20250 b7a3e21831c242448e7adb02269086e5 198 SUPERFAMILY SSF57802 1 38 4.71E-11 T 22-04-2016 HRM2_RS21535 5dcd59c482f22b9958c6b94e7b83f7e5 221 Gene3D G3DSA:1.10.3720.10 10 213 1.2E-42 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS21535 5dcd59c482f22b9958c6b94e7b83f7e5 221 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 108 9.2E-26 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HRM2_RS21535 5dcd59c482f22b9958c6b94e7b83f7e5 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 213 3.2E-18 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS21535 5dcd59c482f22b9958c6b94e7b83f7e5 221 PANTHER PTHR30614 1 219 1.2E-74 T 22-04-2016 HRM2_RS21535 5dcd59c482f22b9958c6b94e7b83f7e5 221 SUPERFAMILY SSF161098 12 199 1.19E-37 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS11830 dcd0a43cf6d5a5665da8b511450c2c9d 231 PIRSF PIRSF006102 4 229 9.4E-42 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 HRM2_RS11830 dcd0a43cf6d5a5665da8b511450c2c9d 231 PANTHER PTHR30335:SF0 5 225 6.1E-74 T 22-04-2016 HRM2_RS11830 dcd0a43cf6d5a5665da8b511450c2c9d 231 PANTHER PTHR30335 5 225 6.1E-74 T 22-04-2016 HRM2_RS11830 dcd0a43cf6d5a5665da8b511450c2c9d 231 Pfam PF02508 Rnf-Nqr subunit, membrane protein 8 222 6.6E-49 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 HRM2_RS24150 b20d89e4a0a28b563fbe6186b498c10b 638 PANTHER PTHR11731:SF140 77 637 5.1E-127 T 22-04-2016 HRM2_RS24150 b20d89e4a0a28b563fbe6186b498c10b 638 PANTHER PTHR11731 77 637 5.1E-127 T 22-04-2016 HRM2_RS24150 b20d89e4a0a28b563fbe6186b498c10b 638 Gene3D G3DSA:3.40.50.1820 322 629 1.1E-93 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS24150 b20d89e4a0a28b563fbe6186b498c10b 638 SUPERFAMILY SSF53474 376 629 2.53E-72 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS24150 b20d89e4a0a28b563fbe6186b498c10b 638 Gene3D G3DSA:2.120.10.30 42 274 2.1E-22 T 22-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like HRM2_RS24150 b20d89e4a0a28b563fbe6186b498c10b 638 SUPERFAMILY SSF82171 46 369 7.26E-19 T 22-04-2016 HRM2_RS24150 b20d89e4a0a28b563fbe6186b498c10b 638 Pfam PF00326 Prolyl oligopeptidase family 418 630 8.1E-47 T 22-04-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 HRM2_RS20650 7f19d3cc07705a156f6b4891cceec5fd 271 SMART SM00062 15 254 2.6E-4 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS20650 7f19d3cc07705a156f6b4891cceec5fd 271 Gene3D G3DSA:3.40.190.10 95 211 9.4E-6 T 22-04-2016 HRM2_RS20650 7f19d3cc07705a156f6b4891cceec5fd 271 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 18 251 1.4E-20 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HRM2_RS20650 7f19d3cc07705a156f6b4891cceec5fd 271 SUPERFAMILY SSF53850 16 252 1.97E-33 T 22-04-2016 HRM2_RS20650 7f19d3cc07705a156f6b4891cceec5fd 271 Gene3D G3DSA:3.40.190.10 12 94 1.6E-20 T 22-04-2016 HRM2_RS20650 7f19d3cc07705a156f6b4891cceec5fd 271 Gene3D G3DSA:3.40.190.10 212 251 1.6E-20 T 22-04-2016 HRM2_RS20650 7f19d3cc07705a156f6b4891cceec5fd 271 PANTHER PTHR18966 75 252 5.8E-13 T 22-04-2016 HRM2_RS20650 7f19d3cc07705a156f6b4891cceec5fd 271 PANTHER PTHR18966 22 57 5.8E-13 T 22-04-2016 HRM2_RS14030 b6fadcc726ee2ca37d4586b3371657d1 492 PANTHER PTHR30121 22 444 2.8E-162 T 22-04-2016 HRM2_RS14030 b6fadcc726ee2ca37d4586b3371657d1 492 PANTHER PTHR30121:SF3 22 444 2.8E-162 T 22-04-2016 HRM2_RS14030 b6fadcc726ee2ca37d4586b3371657d1 492 Gene3D G3DSA:3.40.50.300 23 110 3.4E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14030 b6fadcc726ee2ca37d4586b3371657d1 492 Gene3D G3DSA:3.40.50.300 206 387 3.4E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14030 b6fadcc726ee2ca37d4586b3371657d1 492 SUPERFAMILY SSF52540 23 387 2.83E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS14030 b6fadcc726ee2ca37d4586b3371657d1 492 Pfam PF05872 Bacterial protein of unknown function (DUF853) 17 492 3.8E-217 T 22-04-2016 IPR033186 Helicase HerA-like C-terminal HRM2_RS25595 0cb8949a71c0a7ff9bb3adde1c6521a1 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 9.2E-10 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS25595 0cb8949a71c0a7ff9bb3adde1c6521a1 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 9.2E-10 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS25595 0cb8949a71c0a7ff9bb3adde1c6521a1 205 PANTHER PTHR30055 5 184 7.3E-21 T 22-04-2016 HRM2_RS25595 0cb8949a71c0a7ff9bb3adde1c6521a1 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 1.8E-16 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS25595 0cb8949a71c0a7ff9bb3adde1c6521a1 205 SUPERFAMILY SSF46689 11 79 1.75E-16 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS25595 0cb8949a71c0a7ff9bb3adde1c6521a1 205 Gene3D G3DSA:1.10.357.10 12 183 7.5E-29 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HRM2_RS08315 4e5275bcf3eccbc21e9219316dcfe1b7 149 PANTHER PTHR10093 33 148 7.8E-15 T 22-04-2016 HRM2_RS08315 4e5275bcf3eccbc21e9219316dcfe1b7 149 SUPERFAMILY SSF82649 30 142 7.85E-24 T 22-04-2016 HRM2_RS08315 4e5275bcf3eccbc21e9219316dcfe1b7 149 Gene3D G3DSA:3.90.1010.10 29 143 6.4E-21 T 22-04-2016 HRM2_RS08315 4e5275bcf3eccbc21e9219316dcfe1b7 149 PANTHER PTHR10093:SF1 33 148 7.8E-15 T 22-04-2016 HRM2_RS08315 4e5275bcf3eccbc21e9219316dcfe1b7 149 Pfam PF01592 NifU-like N terminal domain 29 140 7.9E-20 T 22-04-2016 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 HRM2_RS23660 1b16fda6438e8b142d15034772a990a3 252 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 227 1.7E-24 T 22-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 HRM2_RS23660 1b16fda6438e8b142d15034772a990a3 252 SUPERFAMILY SSF52096 13 241 8.22E-37 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS23660 1b16fda6438e8b142d15034772a990a3 252 PANTHER PTHR11941 38 244 4.3E-27 T 22-04-2016 HRM2_RS23660 1b16fda6438e8b142d15034772a990a3 252 Gene3D G3DSA:3.90.226.10 13 237 5.6E-38 T 22-04-2016 IPR029045 ClpP/crotonase-like domain HRM2_RS09645 d18a1195da7359335f765695aa8e0fde 187 PANTHER PTHR30471 33 179 5.9E-45 T 22-04-2016 HRM2_RS09645 d18a1195da7359335f765695aa8e0fde 187 Pfam PF04002 RadC-like JAB domain 56 178 1.5E-40 T 22-04-2016 IPR025657 RadC-like JAB domain HRM2_RS09645 d18a1195da7359335f765695aa8e0fde 187 Gene3D G3DSA:3.40.140.10 51 179 2.7E-41 T 22-04-2016 HRM2_RS09645 d18a1195da7359335f765695aa8e0fde 187 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 126 131 - T 22-04-2016 IPR020891 Uncharacterised protein family UPF0758, conserved site HRM2_RS11050 51c6890f3e581fe714c3c80c334a4790 336 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 204 214 1.6E-18 T 22-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 HRM2_RS11050 51c6890f3e581fe714c3c80c334a4790 336 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 69 88 1.6E-18 T 22-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 HRM2_RS11050 51c6890f3e581fe714c3c80c334a4790 336 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 153 174 1.6E-18 T 22-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 HRM2_RS11050 51c6890f3e581fe714c3c80c334a4790 336 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 17 33 1.6E-18 T 22-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 HRM2_RS11050 51c6890f3e581fe714c3c80c334a4790 336 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 6 333 8.2E-90 T 22-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 HRM2_RS11050 51c6890f3e581fe714c3c80c334a4790 336 PANTHER PTHR10055 7 336 2.9E-170 T 22-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 HRM2_RS11050 51c6890f3e581fe714c3c80c334a4790 336 SUPERFAMILY SSF52374 8 333 1.75E-83 T 22-04-2016 HRM2_RS11050 51c6890f3e581fe714c3c80c334a4790 336 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 4 334 35.409 T 22-04-2016 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2 HRM2_RS11050 51c6890f3e581fe714c3c80c334a4790 336 Gene3D G3DSA:3.40.50.620 3 213 9.1E-76 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS11050 51c6890f3e581fe714c3c80c334a4790 336 Gene3D G3DSA:1.10.240.10 214 299 3.2E-29 T 22-04-2016 HRM2_RS11050 51c6890f3e581fe714c3c80c334a4790 336 Pfam PF00579 tRNA synthetases class I (W and Y) 4 288 1.0E-54 T 22-04-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HRM2_RS11050 51c6890f3e581fe714c3c80c334a4790 336 PANTHER PTHR10055:SF11 7 336 2.9E-170 T 22-04-2016 HRM2_RS02375 cfa5d1b63237805456df64d798079a19 173 Pfam PF01202 Shikimate kinase 16 165 2.2E-31 T 22-04-2016 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS02375 cfa5d1b63237805456df64d798079a19 173 PANTHER PTHR21087 1 166 2.6E-35 T 22-04-2016 HRM2_RS02375 cfa5d1b63237805456df64d798079a19 173 Gene3D G3DSA:3.40.50.300 4 167 3.6E-40 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02375 cfa5d1b63237805456df64d798079a19 173 Hamap MF_00109 Shikimate kinase [aroK]. 6 169 20.367 T 22-04-2016 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 HRM2_RS02375 cfa5d1b63237805456df64d798079a19 173 PANTHER PTHR21087:SF0 1 166 2.6E-35 T 22-04-2016 HRM2_RS02375 cfa5d1b63237805456df64d798079a19 173 SUPERFAMILY SSF52540 1 167 9.76E-22 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS02375 cfa5d1b63237805456df64d798079a19 173 PRINTS PR01100 Shikimate kinase family signature 99 116 1.2E-17 T 22-04-2016 HRM2_RS02375 cfa5d1b63237805456df64d798079a19 173 PRINTS PR01100 Shikimate kinase family signature 78 87 1.2E-17 T 22-04-2016 HRM2_RS02375 cfa5d1b63237805456df64d798079a19 173 PRINTS PR01100 Shikimate kinase family signature 9 24 1.2E-17 T 22-04-2016 HRM2_RS02375 cfa5d1b63237805456df64d798079a19 173 PRINTS PR01100 Shikimate kinase family signature 33 46 1.2E-17 T 22-04-2016 HRM2_RS02375 cfa5d1b63237805456df64d798079a19 173 PRINTS PR01100 Shikimate kinase family signature 61 69 1.2E-17 T 22-04-2016 HRM2_RS19160 5391cec7c71b334a14a463044daf1769 425 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 16 421 2.0E-115 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS19160 5391cec7c71b334a14a463044daf1769 425 PANTHER PTHR33362:SF2 1 424 4.9E-110 T 22-04-2016 HRM2_RS19160 5391cec7c71b334a14a463044daf1769 425 PANTHER PTHR33362 1 424 4.9E-110 T 22-04-2016 HRM2_RS19160 5391cec7c71b334a14a463044daf1769 425 PIRSF PIRSF006066 1 425 3.9E-130 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS19160 5391cec7c71b334a14a463044daf1769 425 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 6 416 2.3E-107 T 22-04-2016 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit HRM2_RS24850 5225237783fa850c8dc9d137761fc98d 268 SUPERFAMILY SSF52402 8 263 4.05E-45 T 22-04-2016 HRM2_RS24850 5225237783fa850c8dc9d137761fc98d 268 PANTHER PTHR21294:SF0 8 268 8.0E-47 T 22-04-2016 HRM2_RS24850 5225237783fa850c8dc9d137761fc98d 268 PANTHER PTHR21294 8 268 8.0E-47 T 22-04-2016 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 HRM2_RS24850 5225237783fa850c8dc9d137761fc98d 268 PIRSF PIRSF000090 8 268 1.8E-49 T 22-04-2016 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 HRM2_RS24850 5225237783fa850c8dc9d137761fc98d 268 Gene3D G3DSA:3.40.50.620 8 267 7.7E-64 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS24850 5225237783fa850c8dc9d137761fc98d 268 Pfam PF01012 Electron transfer flavoprotein domain 22 221 4.6E-29 T 22-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 HRM2_RS24850 5225237783fa850c8dc9d137761fc98d 268 SMART SM00893 16 228 1.8E-24 T 22-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 HRM2_RS14280 875f56286ec9d02b19eed3aa938bfe6c 296 PANTHER PTHR11358:SF2 1 295 2.8E-110 T 22-04-2016 HRM2_RS14280 875f56286ec9d02b19eed3aa938bfe6c 296 PANTHER PTHR11358 1 295 2.8E-110 T 22-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 HRM2_RS14280 875f56286ec9d02b19eed3aa938bfe6c 296 TIGRFAM TIGR01229 rocF_arginase: arginase 6 295 3.1E-92 T 22-04-2016 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: REACT_13|UniPathway: UPA00158 HRM2_RS14280 875f56286ec9d02b19eed3aa938bfe6c 296 PIRSF PIRSF036979 1 294 3.4E-39 T 22-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 HRM2_RS14280 875f56286ec9d02b19eed3aa938bfe6c 296 ProSitePatterns PS01053 Arginase family signature. 221 242 - T 22-04-2016 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 Reactome: REACT_13 HRM2_RS14280 875f56286ec9d02b19eed3aa938bfe6c 296 PRINTS PR00116 Arginase signature 94 109 2.9E-32 T 22-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 HRM2_RS14280 875f56286ec9d02b19eed3aa938bfe6c 296 PRINTS PR00116 Arginase signature 253 267 2.9E-32 T 22-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 HRM2_RS14280 875f56286ec9d02b19eed3aa938bfe6c 296 PRINTS PR00116 Arginase signature 170 188 2.9E-32 T 22-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 HRM2_RS14280 875f56286ec9d02b19eed3aa938bfe6c 296 PRINTS PR00116 Arginase signature 218 247 2.9E-32 T 22-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 HRM2_RS14280 875f56286ec9d02b19eed3aa938bfe6c 296 Pfam PF00491 Arginase family 4 291 9.3E-76 T 22-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 HRM2_RS14280 875f56286ec9d02b19eed3aa938bfe6c 296 SUPERFAMILY SSF52768 3 293 4.32E-87 T 22-04-2016 HRM2_RS14280 875f56286ec9d02b19eed3aa938bfe6c 296 Gene3D G3DSA:3.40.800.10 2 293 1.4E-92 T 22-04-2016 IPR023696 Ureohydrolase domain HRM2_RS21760 b1c5f86b8039b930c4f9f6559dae7299 481 Pfam PF06253 Trimethylamine methyltransferase (MTTB) 10 476 4.6E-85 T 22-04-2016 IPR010426 Trimethylamine methyltransferase GO:0008168|GO:0015948 KEGG: 00680+2.1.1.250|MetaCyc: PWY-5250|UniPathway: UPA00645 HRM2_RS24060 536b230436672a33e7d5f622b90646af 426 PANTHER PTHR10742 10 422 3.2E-114 T 22-04-2016 HRM2_RS24060 536b230436672a33e7d5f622b90646af 426 Gene3D G3DSA:3.50.50.60 7 102 6.0E-32 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS24060 536b230436672a33e7d5f622b90646af 426 Gene3D G3DSA:3.50.50.60 149 150 6.0E-32 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS24060 536b230436672a33e7d5f622b90646af 426 Gene3D G3DSA:3.50.50.60 209 309 6.0E-32 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS24060 536b230436672a33e7d5f622b90646af 426 Pfam PF01593 Flavin containing amine oxidoreductase 18 313 2.5E-21 T 22-04-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 HRM2_RS24060 536b230436672a33e7d5f622b90646af 426 PANTHER PTHR10742:SF275 10 422 3.2E-114 T 22-04-2016 HRM2_RS24060 536b230436672a33e7d5f622b90646af 426 SUPERFAMILY SSF51905 391 420 9.06E-49 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS24060 536b230436672a33e7d5f622b90646af 426 SUPERFAMILY SSF51905 10 309 9.06E-49 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS08040 dbdef675c2582b9134aba2127ae8014f 338 Gene3D G3DSA:1.10.3470.10 6 336 4.7E-102 T 22-04-2016 IPR029022 ABC transporter, BtuC-like HRM2_RS08040 dbdef675c2582b9134aba2127ae8014f 338 PANTHER PTHR30472 5 338 8.3E-136 T 22-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 HRM2_RS08040 dbdef675c2582b9134aba2127ae8014f 338 Pfam PF01032 FecCD transport family 21 331 4.2E-87 T 22-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 HRM2_RS08040 dbdef675c2582b9134aba2127ae8014f 338 PANTHER PTHR30472:SF34 5 338 8.3E-136 T 22-04-2016 HRM2_RS08040 dbdef675c2582b9134aba2127ae8014f 338 SUPERFAMILY SSF81345 5 331 4.45E-74 T 22-04-2016 IPR029022 ABC transporter, BtuC-like HRM2_RS24365 0fcf8fc69dfa7a4a929991538819bc2f 339 Pfam PF02470 MlaD protein 44 132 7.4E-8 T 22-04-2016 IPR003399 Mce/MlaD HRM2_RS18560 aeb957d622afb830aa17df55b7279a0f 242 PANTHER PTHR32071 9 121 4.3E-18 T 22-04-2016 HRM2_RS18560 aeb957d622afb830aa17df55b7279a0f 242 SUPERFAMILY SSF52172 8 187 9.53E-22 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS18560 aeb957d622afb830aa17df55b7279a0f 242 PANTHER PTHR32071:SF39 9 121 4.3E-18 T 22-04-2016 HRM2_RS18560 aeb957d622afb830aa17df55b7279a0f 242 Pfam PF00072 Response regulator receiver domain 20 121 3.9E-10 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18560 aeb957d622afb830aa17df55b7279a0f 242 Gene3D G3DSA:3.40.50.2300 8 129 2.5E-17 T 22-04-2016 HRM2_RS18560 aeb957d622afb830aa17df55b7279a0f 242 SMART SM00448 7 121 5.7E-8 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS01135 df78ae2cd2d4d92691aac1e70ef15749 330 PANTHER PTHR30472 1 330 1.4E-106 T 22-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 HRM2_RS01135 df78ae2cd2d4d92691aac1e70ef15749 330 SUPERFAMILY SSF81345 2 326 6.28E-80 T 22-04-2016 IPR029022 ABC transporter, BtuC-like HRM2_RS01135 df78ae2cd2d4d92691aac1e70ef15749 330 Gene3D G3DSA:1.10.3470.10 2 328 1.6E-101 T 22-04-2016 IPR029022 ABC transporter, BtuC-like HRM2_RS01135 df78ae2cd2d4d92691aac1e70ef15749 330 Pfam PF01032 FecCD transport family 7 325 1.4E-94 T 22-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 HRM2_RS01135 df78ae2cd2d4d92691aac1e70ef15749 330 PANTHER PTHR30472:SF3 1 330 1.4E-106 T 22-04-2016 HRM2_RS10685 a041baea074a39d03aa2e53433e2a290 287 PANTHER PTHR11825:SF38 4 274 1.2E-78 T 22-04-2016 HRM2_RS10685 a041baea074a39d03aa2e53433e2a290 287 Pfam PF01063 Amino-transferase class IV 30 254 2.3E-38 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 HRM2_RS10685 a041baea074a39d03aa2e53433e2a290 287 SUPERFAMILY SSF56752 3 279 9.68E-70 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 HRM2_RS10685 a041baea074a39d03aa2e53433e2a290 287 PANTHER PTHR11825 4 274 1.2E-78 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 HRM2_RS10685 a041baea074a39d03aa2e53433e2a290 287 Gene3D G3DSA:3.20.10.10 130 278 2.2E-40 T 22-04-2016 HRM2_RS10685 a041baea074a39d03aa2e53433e2a290 287 Gene3D G3DSA:3.30.470.10 4 120 2.3E-30 T 22-04-2016 HRM2_RS18575 a07ebffbe6ea5821e44e15fc7a6ef463 180 PANTHER PTHR11921 5 155 1.1E-29 T 22-04-2016 HRM2_RS18575 a07ebffbe6ea5821e44e15fc7a6ef463 180 Pfam PF02754 Cysteine-rich domain 38 129 1.2E-11 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS18575 a07ebffbe6ea5821e44e15fc7a6ef463 180 PANTHER PTHR11921:SF24 5 155 1.1E-29 T 22-04-2016 HRM2_RS23695 dbef02ca231fb81421af705fc8cdd610 482 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 335 449 5.6E-15 T 22-04-2016 IPR003390 DNA integrity scanning protein, DisA, N-terminal HRM2_RS23695 dbef02ca231fb81421af705fc8cdd610 482 SUPERFAMILY SSF143597 321 449 2.75E-12 T 22-04-2016 HRM2_RS23695 dbef02ca231fb81421af705fc8cdd610 482 Gene3D G3DSA:3.40.1700.10 329 449 4.1E-8 T 22-04-2016 HRM2_RS24880 91b7bcbf3596208541c98afe0300954b 137 PANTHER PTHR23241 22 137 3.7E-13 T 22-04-2016 HRM2_RS24880 91b7bcbf3596208541c98afe0300954b 137 Gene3D G3DSA:1.20.120.20 82 135 7.4E-5 T 22-04-2016 HRM2_RS24880 91b7bcbf3596208541c98afe0300954b 137 Gene3D G3DSA:1.20.120.20 27 81 6.6E-4 T 22-04-2016 HRM2_RS24880 91b7bcbf3596208541c98afe0300954b 137 SUPERFAMILY SSF58113 34 135 2.09E-9 T 22-04-2016 HRM2_RS18135 0a311c4e85d964d5612eb30d770c31de 410 SUPERFAMILY SSF63825 206 364 2.35E-16 T 22-04-2016 HRM2_RS18135 0a311c4e85d964d5612eb30d770c31de 410 SUPERFAMILY SSF63825 132 167 2.35E-16 T 22-04-2016 HRM2_RS18135 0a311c4e85d964d5612eb30d770c31de 410 Gene3D G3DSA:2.130.10.10 132 167 1.7E-9 T 22-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 HRM2_RS18135 0a311c4e85d964d5612eb30d770c31de 410 Gene3D G3DSA:2.130.10.10 206 362 1.7E-9 T 22-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 HRM2_RS18135 0a311c4e85d964d5612eb30d770c31de 410 Pfam PF16261 Domain of unknown function (DUF4915) 267 373 2.4E-9 T 22-04-2016 IPR017481 Conserved hypothetical protein CHP03032 HRM2_RS21970 0e874d7041f4a063ad9234b31a1d0f1f 199 SUPERFAMILY SSF53335 11 152 3.73E-19 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS21970 0e874d7041f4a063ad9234b31a1d0f1f 199 Gene3D G3DSA:3.40.50.150 11 163 1.8E-18 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS21970 0e874d7041f4a063ad9234b31a1d0f1f 199 Pfam PF13847 Methyltransferase domain 26 143 9.3E-11 T 22-04-2016 IPR025714 Methyltransferase domain HRM2_RS07435 652b5227760db0fd0b1713aa6290f960 61 Pfam PF11127 Protein of unknown function (DUF2892) 1 61 7.2E-22 T 22-04-2016 IPR021309 Protein of unknown function DUF2892 HRM2_RS02305 5949868c6317a348b0aaab16a9a182c3 119 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 4 114 2.2E-29 T 22-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 HRM2_RS02305 5949868c6317a348b0aaab16a9a182c3 119 ProSitePatterns PS01319 Ribosome-binding factor A signature. 75 96 - T 22-04-2016 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 HRM2_RS02305 5949868c6317a348b0aaab16a9a182c3 119 Pfam PF02033 Ribosome-binding factor A 6 109 3.1E-31 T 22-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 HRM2_RS02305 5949868c6317a348b0aaab16a9a182c3 119 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 8 96 4.0E-17 T 22-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 HRM2_RS02305 5949868c6317a348b0aaab16a9a182c3 119 SUPERFAMILY SSF89919 2 111 7.33E-33 T 22-04-2016 IPR023799 Ribosome-binding factor A domain HRM2_RS02305 5949868c6317a348b0aaab16a9a182c3 119 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 2 116 21.237 T 22-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 HRM2_RS02305 5949868c6317a348b0aaab16a9a182c3 119 PANTHER PTHR33515 1 119 5.2E-41 T 22-04-2016 HRM2_RS02305 5949868c6317a348b0aaab16a9a182c3 119 Gene3D G3DSA:3.30.300.20 4 115 2.0E-36 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta HRM2_RS25175 14c6ff0e3c5424710bd868082bc08007 453 PANTHER PTHR21666 188 424 2.7E-45 T 22-04-2016 HRM2_RS25175 14c6ff0e3c5424710bd868082bc08007 453 Pfam PF01551 Peptidase family M23 309 403 5.8E-34 T 22-04-2016 IPR016047 Peptidase M23 HRM2_RS25175 14c6ff0e3c5424710bd868082bc08007 453 Gene3D G3DSA:2.70.70.10 269 406 1.2E-46 T 22-04-2016 HRM2_RS25175 14c6ff0e3c5424710bd868082bc08007 453 SUPERFAMILY SSF51261 187 405 1.62E-64 T 22-04-2016 IPR011055 Duplicated hybrid motif HRM2_RS25175 14c6ff0e3c5424710bd868082bc08007 453 PANTHER PTHR21666:SF221 188 424 2.7E-45 T 22-04-2016 HRM2_RS05490 b1f981ff9f674e05201b20e996ca3236 125 Pfam PF03692 Putative zinc- or iron-chelating domain 17 118 2.0E-9 T 22-04-2016 IPR005358 Putative zinc- or iron-chelating domain containing protein HRM2_RS25285 ad7873bc7b2415239c35debd0fb1d5f6 190 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 165 188 2.5E-5 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain HRM2_RS25285 ad7873bc7b2415239c35debd0fb1d5f6 190 Pfam PF07589 PEP-CTERM motif 164 187 7.6E-9 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain HRM2_RS18370 a839cb3ea0a3f7bfa1f2d9d80490179e 615 Pfam PF02120 Flagellar hook-length control protein FliK 485 566 5.2E-16 T 22-04-2016 IPR021136 Flagellar hook-length control protein-like, C-terminal HRM2_RS06270 6aa5f61626f5e455884611f54245b1cd 106 Pfam PF04999 Cell division protein FtsL 26 102 7.2E-8 T 22-04-2016 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 HRM2_RS20430 15db0c294eef62b1fc6a5791ae1e42e9 64 Gene3D G3DSA:3.30.565.10 2 59 1.3E-4 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS22060 eb02efbe940b049a0c0d21a9412f9e9b 658 Gene3D G3DSA:3.40.50.300 1 188 1.8E-26 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22060 eb02efbe940b049a0c0d21a9412f9e9b 658 Gene3D G3DSA:3.40.50.300 255 419 1.8E-26 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22060 eb02efbe940b049a0c0d21a9412f9e9b 658 Pfam PF13175 AAA ATPase domain 1 402 1.2E-46 T 22-04-2016 HRM2_RS22060 eb02efbe940b049a0c0d21a9412f9e9b 658 PANTHER PTHR32182:SF7 465 559 7.8E-12 T 22-04-2016 HRM2_RS22060 eb02efbe940b049a0c0d21a9412f9e9b 658 PANTHER PTHR32182:SF7 1 444 7.8E-12 T 22-04-2016 HRM2_RS22060 eb02efbe940b049a0c0d21a9412f9e9b 658 PANTHER PTHR32182 465 559 7.8E-12 T 22-04-2016 HRM2_RS22060 eb02efbe940b049a0c0d21a9412f9e9b 658 PANTHER PTHR32182 1 444 7.8E-12 T 22-04-2016 HRM2_RS22060 eb02efbe940b049a0c0d21a9412f9e9b 658 SUPERFAMILY SSF52540 1 88 1.65E-19 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS22060 eb02efbe940b049a0c0d21a9412f9e9b 658 SUPERFAMILY SSF52540 250 410 1.65E-19 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11010 2edf1ed73ec6af7dd34531c5a3919de1 152 SUPERFAMILY SSF52172 9 136 9.96E-23 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS11010 2edf1ed73ec6af7dd34531c5a3919de1 152 PANTHER PTHR26402:SF210 7 133 1.3E-17 T 22-04-2016 HRM2_RS11010 2edf1ed73ec6af7dd34531c5a3919de1 152 Gene3D G3DSA:3.40.50.2300 9 133 2.0E-22 T 22-04-2016 HRM2_RS11010 2edf1ed73ec6af7dd34531c5a3919de1 152 PANTHER PTHR26402 7 133 1.3E-17 T 22-04-2016 HRM2_RS11010 2edf1ed73ec6af7dd34531c5a3919de1 152 SMART SM00448 7 127 1.9E-11 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS11010 2edf1ed73ec6af7dd34531c5a3919de1 152 Pfam PF00072 Response regulator receiver domain 10 127 5.5E-14 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS04175 6b507d148814dffdc31659d8282a96fc 159 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 24 153 8.0E-29 T 22-04-2016 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component HRM2_RS04175 6b507d148814dffdc31659d8282a96fc 159 PANTHER PTHR35011 1 154 1.1E-23 T 22-04-2016 HRM2_RS21205 a5e356fd1fd650a13a77b2ee054a201b 255 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 3 251 4.0E-86 T 22-04-2016 IPR008275 CoA enzyme activase HRM2_RS21205 a5e356fd1fd650a13a77b2ee054a201b 255 SUPERFAMILY SSF53067 1 253 1.74E-36 T 22-04-2016 HRM2_RS21205 a5e356fd1fd650a13a77b2ee054a201b 255 PANTHER PTHR32329 1 255 1.8E-108 T 22-04-2016 HRM2_RS21205 a5e356fd1fd650a13a77b2ee054a201b 255 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 5 252 3.4E-59 T 22-04-2016 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type HRM2_RS21205 a5e356fd1fd650a13a77b2ee054a201b 255 Gene3D G3DSA:3.30.420.40 97 233 1.4E-49 T 22-04-2016 HRM2_RS23865 df888fd2b01aa7cb92bbe3d64a89b170 355 PANTHER PTHR34184 37 355 5.3E-163 T 22-04-2016 HRM2_RS23865 df888fd2b01aa7cb92bbe3d64a89b170 355 PANTHER PTHR34184:SF2 37 355 5.3E-163 T 22-04-2016 HRM2_RS23865 df888fd2b01aa7cb92bbe3d64a89b170 355 Pfam PF03773 Predicted permease 60 352 5.6E-72 T 22-04-2016 IPR005524 Predicted permease DUF318 HRM2_RS20235 da27c0b5670c805e03e17d0c02e01a22 60 Gene3D G3DSA:2.20.25.10 20 47 3.8E-4 T 22-04-2016 HRM2_RS01615 d95c8885a1c1245e3d7b7eca5a17aa2a 96 Gene3D G3DSA:2.60.40.10 7 83 1.0E-15 T 22-04-2016 IPR013783 Immunoglobulin-like fold HRM2_RS01615 d95c8885a1c1245e3d7b7eca5a17aa2a 96 SUPERFAMILY SSF81296 15 95 8.2E-23 T 22-04-2016 IPR014756 Immunoglobulin E-set HRM2_RS01615 d95c8885a1c1245e3d7b7eca5a17aa2a 96 Pfam PF16561 Glycogen recognition site of AMP-activated protein kinase 16 96 8.6E-16 T 22-04-2016 IPR032640 AMP-activated protein kinase, glycogen-binding domain HRM2_RS12545 dcd1cea0573c64d94651bdd4bdaef592 291 Pfam PF00483 Nucleotidyl transferase 3 238 1.4E-68 T 22-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 HRM2_RS12545 dcd1cea0573c64d94651bdd4bdaef592 291 PANTHER PTHR22572 3 270 2.5E-168 T 22-04-2016 HRM2_RS12545 dcd1cea0573c64d94651bdd4bdaef592 291 SUPERFAMILY SSF53448 2 287 1.94E-89 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS12545 dcd1cea0573c64d94651bdd4bdaef592 291 PANTHER PTHR22572:SF105 3 270 2.5E-168 T 22-04-2016 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 HRM2_RS12545 dcd1cea0573c64d94651bdd4bdaef592 291 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 3 287 8.2E-150 T 22-04-2016 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 HRM2_RS12545 dcd1cea0573c64d94651bdd4bdaef592 291 Gene3D G3DSA:3.90.550.10 1 264 9.4E-68 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS00960 dd83751aeb81028ef517506f22a19908 451 PANTHER PTHR10283 11 451 2.4E-142 T 22-04-2016 HRM2_RS00960 dd83751aeb81028ef517506f22a19908 451 PANTHER PTHR10283:SF91 11 451 2.4E-142 T 22-04-2016 HRM2_RS00960 dd83751aeb81028ef517506f22a19908 451 Pfam PF03600 Citrate transporter 22 396 1.4E-70 T 22-04-2016 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 HRM2_RS18840 1bf5afe413ac72cbbefd3e00fad5782d 140 Gene3D G3DSA:3.40.50.2300 8 134 1.2E-25 T 22-04-2016 HRM2_RS18840 1bf5afe413ac72cbbefd3e00fad5782d 140 SUPERFAMILY SSF52172 8 134 1.57E-26 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS18840 1bf5afe413ac72cbbefd3e00fad5782d 140 Pfam PF00072 Response regulator receiver domain 13 129 2.8E-19 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18840 1bf5afe413ac72cbbefd3e00fad5782d 140 SMART SM00448 10 129 8.3E-18 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS18840 1bf5afe413ac72cbbefd3e00fad5782d 140 PANTHER PTHR26402 10 130 1.6E-21 T 22-04-2016 HRM2_RS17705 c59709047b5759a1826bdf7d471284d8 162 SUPERFAMILY SSF54427 25 128 1.64E-31 T 22-04-2016 IPR032710 NTF2-like domain HRM2_RS17705 c59709047b5759a1826bdf7d471284d8 162 PANTHER PTHR33747 1 162 2.0E-33 T 22-04-2016 HRM2_RS17705 c59709047b5759a1826bdf7d471284d8 162 PANTHER PTHR33747:SF1 1 162 2.0E-33 T 22-04-2016 HRM2_RS17705 c59709047b5759a1826bdf7d471284d8 162 SUPERFAMILY SSF103642 141 161 1.32E-7 T 22-04-2016 HRM2_RS17705 c59709047b5759a1826bdf7d471284d8 162 Gene3D G3DSA:3.10.450.50 2 162 6.1E-52 T 22-04-2016 IPR032710 NTF2-like domain HRM2_RS17705 c59709047b5759a1826bdf7d471284d8 162 Pfam PF02810 SEC-C motif 144 162 9.7E-10 T 22-04-2016 IPR004027 SEC-C motif HRM2_RS19010 65532bb8be973810e4a03e20578c9ae2 140 PANTHER PTHR33570 43 139 2.1E-18 T 22-04-2016 HRM2_RS19010 65532bb8be973810e4a03e20578c9ae2 140 Pfam PF02627 Carboxymuconolactone decarboxylase family 46 128 1.7E-17 T 22-04-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 HRM2_RS19010 65532bb8be973810e4a03e20578c9ae2 140 PANTHER PTHR33570:SF2 43 139 2.1E-18 T 22-04-2016 HRM2_RS19010 65532bb8be973810e4a03e20578c9ae2 140 SUPERFAMILY SSF69118 16 136 4.8E-28 T 22-04-2016 IPR029032 AhpD-like HRM2_RS19010 65532bb8be973810e4a03e20578c9ae2 140 Gene3D G3DSA:1.20.1290.10 25 135 6.7E-23 T 22-04-2016 IPR029032 AhpD-like HRM2_RS19365 21004d5a02bed12c08a9136d7908b695 327 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 3 311 6.8E-76 T 22-04-2016 IPR004481 Sodium/potassium/calcium exchanger Reactome: REACT_15518 HRM2_RS19365 21004d5a02bed12c08a9136d7908b695 327 Pfam PF01699 Sodium/calcium exchanger protein 174 317 2.0E-34 T 22-04-2016 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: REACT_15518 HRM2_RS19365 21004d5a02bed12c08a9136d7908b695 327 Pfam PF01699 Sodium/calcium exchanger protein 6 143 2.7E-26 T 22-04-2016 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: REACT_15518 HRM2_RS19365 21004d5a02bed12c08a9136d7908b695 327 PANTHER PTHR10846 19 318 1.1E-64 T 22-04-2016 IPR004481 Sodium/potassium/calcium exchanger Reactome: REACT_15518 HRM2_RS07920 88d988a529084101adde3036c7a1474a 493 Pfam PF06253 Trimethylamine methyltransferase (MTTB) 8 472 5.8E-86 T 22-04-2016 IPR010426 Trimethylamine methyltransferase GO:0008168|GO:0015948 KEGG: 00680+2.1.1.250|MetaCyc: PWY-5250|UniPathway: UPA00645 HRM2_RS01795 2b55f8b6b6c95ee9cd6fb4172a485b54 477 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 22-04-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 HRM2_RS01795 2b55f8b6b6c95ee9cd6fb4172a485b54 477 PANTHER PTHR11699 2 470 2.7E-182 T 22-04-2016 HRM2_RS01795 2b55f8b6b6c95ee9cd6fb4172a485b54 477 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 247 254 - T 22-04-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 HRM2_RS01795 2b55f8b6b6c95ee9cd6fb4172a485b54 477 SUPERFAMILY SSF53720 4 474 1.23E-148 T 22-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 HRM2_RS01795 2b55f8b6b6c95ee9cd6fb4172a485b54 477 Gene3D G3DSA:3.40.309.10 262 440 1.4E-63 T 22-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 HRM2_RS01795 2b55f8b6b6c95ee9cd6fb4172a485b54 477 Gene3D G3DSA:3.40.605.10 4 261 8.7E-86 T 22-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 HRM2_RS01795 2b55f8b6b6c95ee9cd6fb4172a485b54 477 Pfam PF00171 Aldehyde dehydrogenase family 15 471 3.3E-156 T 22-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 HRM2_RS23370 2333c88100327e761b272189ba296c44 200 Pfam PF12822 Protein of unknown function (DUF3816) 12 179 1.8E-10 T 22-04-2016 IPR024529 ECF transporter, substrate-specific component GO:0005215 HRM2_RS05810 cf742f3b7e51e58769ae1b2617bfa6ca 449 SUPERFAMILY SSF56762 1 449 6.41E-118 T 22-04-2016 IPR029014 NiFe hydrogenase-like HRM2_RS05810 cf742f3b7e51e58769ae1b2617bfa6ca 449 Gene3D G3DSA:1.10.645.10 1 449 5.0E-102 T 22-04-2016 IPR029014 NiFe hydrogenase-like HRM2_RS05810 cf742f3b7e51e58769ae1b2617bfa6ca 449 PANTHER PTHR11993:SF9 259 449 2.1E-129 T 22-04-2016 HRM2_RS05810 cf742f3b7e51e58769ae1b2617bfa6ca 449 PANTHER PTHR11993:SF9 3 117 2.1E-129 T 22-04-2016 HRM2_RS05810 cf742f3b7e51e58769ae1b2617bfa6ca 449 PANTHER PTHR11993:SF9 136 204 2.1E-129 T 22-04-2016 HRM2_RS05810 cf742f3b7e51e58769ae1b2617bfa6ca 449 PANTHER PTHR11993 259 449 2.1E-129 T 22-04-2016 HRM2_RS05810 cf742f3b7e51e58769ae1b2617bfa6ca 449 PANTHER PTHR11993 3 117 2.1E-129 T 22-04-2016 HRM2_RS05810 cf742f3b7e51e58769ae1b2617bfa6ca 449 PANTHER PTHR11993 136 204 2.1E-129 T 22-04-2016 HRM2_RS05810 cf742f3b7e51e58769ae1b2617bfa6ca 449 Pfam PF00374 Nickel-dependent hydrogenase 360 427 9.4E-7 T 22-04-2016 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 HRM2_RS05810 cf742f3b7e51e58769ae1b2617bfa6ca 449 Pfam PF00374 Nickel-dependent hydrogenase 40 118 1.0E-20 T 22-04-2016 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 HRM2_RS19185 dc1402c0a45b9b26fefc7e00b4420856 165 PANTHER PTHR33169 6 156 3.4E-20 T 22-04-2016 HRM2_RS19185 dc1402c0a45b9b26fefc7e00b4420856 165 Pfam PF10400 Virulence activator alpha C-term 90 156 1.2E-9 T 22-04-2016 IPR018309 Transcription regulator PadR, C-terminal HRM2_RS19185 dc1402c0a45b9b26fefc7e00b4420856 165 Gene3D G3DSA:1.10.10.10 1 82 2.0E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS19185 dc1402c0a45b9b26fefc7e00b4420856 165 SUPERFAMILY SSF46785 3 161 2.21E-30 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS19185 dc1402c0a45b9b26fefc7e00b4420856 165 PANTHER PTHR33169:SF4 6 156 3.4E-20 T 22-04-2016 HRM2_RS19185 dc1402c0a45b9b26fefc7e00b4420856 165 Pfam PF03551 Transcriptional regulator PadR-like family 6 79 4.4E-12 T 22-04-2016 IPR005149 Transcription regulator PadR, N-terminal HRM2_RS11480 2931f5153a2cf55adab36708241eeeb7 176 Pfam PF02677 Uncharacterized BCR, COG1636 3 170 5.2E-57 T 22-04-2016 IPR003828 Protein of unknown function DUF208 HRM2_RS11480 2931f5153a2cf55adab36708241eeeb7 176 PANTHER PTHR36701 2 176 2.9E-64 T 22-04-2016 HRM2_RS19525 5943a18e80b0df5ca00bd17094b6be98 453 Gene3D G3DSA:3.40.50.620 21 132 1.6E-11 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS19525 5943a18e80b0df5ca00bd17094b6be98 453 Gene3D G3DSA:1.10.579.10 297 446 4.1E-15 T 22-04-2016 HRM2_RS19525 5943a18e80b0df5ca00bd17094b6be98 453 SUPERFAMILY SSF52425 20 184 7.06E-33 T 22-04-2016 IPR006050 DNA photolyase, N-terminal HRM2_RS19525 5943a18e80b0df5ca00bd17094b6be98 453 PANTHER PTHR10211:SF0 16 453 9.4E-148 T 22-04-2016 IPR008148 DNA photolyase class 2 GO:0003904|GO:0006281 HRM2_RS19525 5943a18e80b0df5ca00bd17094b6be98 453 Pfam PF00875 DNA photolyase 21 177 8.5E-23 T 22-04-2016 IPR006050 DNA photolyase, N-terminal HRM2_RS19525 5943a18e80b0df5ca00bd17094b6be98 453 SUPERFAMILY SSF48173 209 448 1.31E-51 T 22-04-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain HRM2_RS19525 5943a18e80b0df5ca00bd17094b6be98 453 PANTHER PTHR10211 16 453 9.4E-148 T 22-04-2016 HRM2_RS19525 5943a18e80b0df5ca00bd17094b6be98 453 Gene3D G3DSA:1.25.40.80 197 296 8.7E-25 T 22-04-2016 HRM2_RS03060 ac7a62d7db38e8d8023764758698f639 140 Pfam PF04277 Oxaloacetate decarboxylase, gamma chain 11 61 4.3E-6 T 22-04-2016 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0071436 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 HRM2_RS23365 726e6cb8d424ae90c95a43e14e3a9cc5 132 Gene3D G3DSA:3.30.1330.80 1 130 5.8E-43 T 22-04-2016 HRM2_RS23365 726e6cb8d424ae90c95a43e14e3a9cc5 132 PANTHER PTHR34988 4 132 1.0E-36 T 22-04-2016 HRM2_RS23365 726e6cb8d424ae90c95a43e14e3a9cc5 132 SUPERFAMILY SSF117856 3 128 6.28E-34 T 22-04-2016 HRM2_RS23365 726e6cb8d424ae90c95a43e14e3a9cc5 132 Pfam PF03479 Domain of unknown function (DUF296) 4 107 7.2E-24 T 22-04-2016 IPR005175 PPC domain HRM2_RS12585 fa7f59c8cb909312c2bf938cc90ec763 371 Pfam PF04230 Polysaccharide pyruvyl transferase 16 299 1.4E-14 T 22-04-2016 IPR007345 Polysaccharide pyruvyl transferase HRM2_RS12525 72ab598e32159ba084dc662b88385bd9 298 Pfam PF04754 Putative transposase, YhgA-like 3 186 1.9E-5 T 22-04-2016 IPR006842 Transposase (putative), YhgA-like HRM2_RS11665 c2252ec3c94fc3c8ed55d629c02a6485 321 SUPERFAMILY SSF53474 34 320 5.97E-65 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS11665 c2252ec3c94fc3c8ed55d629c02a6485 321 PANTHER PTHR10992 36 320 4.3E-58 T 22-04-2016 HRM2_RS11665 c2252ec3c94fc3c8ed55d629c02a6485 321 PRINTS PR00111 Alpha/beta hydrolase fold signature 84 99 1.9E-5 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HRM2_RS11665 c2252ec3c94fc3c8ed55d629c02a6485 321 PRINTS PR00111 Alpha/beta hydrolase fold signature 146 159 1.9E-5 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HRM2_RS11665 c2252ec3c94fc3c8ed55d629c02a6485 321 PRINTS PR00111 Alpha/beta hydrolase fold signature 132 145 1.9E-5 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HRM2_RS11665 c2252ec3c94fc3c8ed55d629c02a6485 321 Pfam PF00561 alpha/beta hydrolase fold 60 307 2.2E-30 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HRM2_RS11665 c2252ec3c94fc3c8ed55d629c02a6485 321 PRINTS PR00412 Epoxide hydrolase signature 65 83 2.5E-7 T 22-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 HRM2_RS11665 c2252ec3c94fc3c8ed55d629c02a6485 321 PRINTS PR00412 Epoxide hydrolase signature 295 317 2.5E-7 T 22-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 HRM2_RS11665 c2252ec3c94fc3c8ed55d629c02a6485 321 PRINTS PR00412 Epoxide hydrolase signature 262 278 2.5E-7 T 22-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 HRM2_RS11665 c2252ec3c94fc3c8ed55d629c02a6485 321 PRINTS PR00412 Epoxide hydrolase signature 132 145 2.5E-7 T 22-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 HRM2_RS11665 c2252ec3c94fc3c8ed55d629c02a6485 321 PANTHER PTHR10992:SF773 36 320 4.3E-58 T 22-04-2016 HRM2_RS11665 c2252ec3c94fc3c8ed55d629c02a6485 321 Gene3D G3DSA:3.40.50.1820 34 320 3.7E-68 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS10720 e8fb731120e93d91627e52e7e49fcb02 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 60 2.9E-15 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS10720 e8fb731120e93d91627e52e7e49fcb02 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 3.2E-8 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS10720 e8fb731120e93d91627e52e7e49fcb02 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 3.2E-8 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS10720 e8fb731120e93d91627e52e7e49fcb02 210 SUPERFAMILY SSF48498 86 208 5.5E-10 T 22-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal HRM2_RS10720 e8fb731120e93d91627e52e7e49fcb02 210 Gene3D G3DSA:1.10.357.10 7 208 6.5E-39 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HRM2_RS10720 e8fb731120e93d91627e52e7e49fcb02 210 PANTHER PTHR30055 3 178 1.4E-24 T 22-04-2016 HRM2_RS10720 e8fb731120e93d91627e52e7e49fcb02 210 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 60 - T 22-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site HRM2_RS10720 e8fb731120e93d91627e52e7e49fcb02 210 SUPERFAMILY SSF46689 8 81 2.64E-18 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS23550 e5e7183bf9d8707face3a572a0a4fff9 319 Pfam PF00676 Dehydrogenase E1 component 14 310 8.5E-86 T 22-04-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 HRM2_RS23550 e5e7183bf9d8707face3a572a0a4fff9 319 Gene3D G3DSA:3.40.50.970 2 319 3.1E-129 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS23550 e5e7183bf9d8707face3a572a0a4fff9 319 PANTHER PTHR11516 3 319 5.4E-143 T 22-04-2016 HRM2_RS23550 e5e7183bf9d8707face3a572a0a4fff9 319 SUPERFAMILY SSF52518 2 319 7.68E-106 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold HRM2_RS14270 fe1fe4077d875930088d5989c1d8dde0 205 SUPERFAMILY SSF53335 29 184 7.05E-30 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS14270 fe1fe4077d875930088d5989c1d8dde0 205 PANTHER PTHR10108 20 181 7.3E-24 T 22-04-2016 HRM2_RS14270 fe1fe4077d875930088d5989c1d8dde0 205 Gene3D G3DSA:3.40.50.150 27 183 6.2E-27 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS14270 fe1fe4077d875930088d5989c1d8dde0 205 Pfam PF08241 Methyltransferase domain 38 134 3.6E-17 T 22-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 HRM2_RS14270 fe1fe4077d875930088d5989c1d8dde0 205 PANTHER PTHR10108:SF714 20 181 7.3E-24 T 22-04-2016 HRM2_RS22105 4d0c9ed46b1132cf4bb97dbf2e320f55 372 PANTHER PTHR10108:SF795 103 278 2.8E-89 T 22-04-2016 HRM2_RS22105 4d0c9ed46b1132cf4bb97dbf2e320f55 372 PANTHER PTHR10108:SF795 294 363 2.8E-89 T 22-04-2016 HRM2_RS22105 4d0c9ed46b1132cf4bb97dbf2e320f55 372 PIRSF PIRSF003085 3 371 5.7E-107 T 22-04-2016 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 HRM2_RS22105 4d0c9ed46b1132cf4bb97dbf2e320f55 372 Gene3D G3DSA:3.40.50.150 108 361 2.2E-83 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS22105 4d0c9ed46b1132cf4bb97dbf2e320f55 372 PANTHER PTHR10108 103 278 2.8E-89 T 22-04-2016 HRM2_RS22105 4d0c9ed46b1132cf4bb97dbf2e320f55 372 PANTHER PTHR10108 294 363 2.8E-89 T 22-04-2016 HRM2_RS22105 4d0c9ed46b1132cf4bb97dbf2e320f55 372 SUPERFAMILY SSF53335 108 362 4.06E-72 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS22105 4d0c9ed46b1132cf4bb97dbf2e320f55 372 Pfam PF02353 Mycolic acid cyclopropane synthetase 103 357 6.2E-83 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS06110 f38fb2fe86f77b9cddd9402c3cce98e7 228 SUPERFAMILY SSF48452 30 108 3.8E-10 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS06110 f38fb2fe86f77b9cddd9402c3cce98e7 228 SUPERFAMILY SSF48452 171 204 3.8E-10 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS06110 f38fb2fe86f77b9cddd9402c3cce98e7 228 Pfam PF13525 Outer membrane lipoprotein 29 207 1.6E-44 T 22-04-2016 HRM2_RS06110 f38fb2fe86f77b9cddd9402c3cce98e7 228 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 5 212 9.8E-63 T 22-04-2016 IPR017689 Outer membrane protein assembly factor BamD HRM2_RS06110 f38fb2fe86f77b9cddd9402c3cce98e7 228 PANTHER PTHR37423 1 209 9.4E-29 T 22-04-2016 HRM2_RS06110 f38fb2fe86f77b9cddd9402c3cce98e7 228 Gene3D G3DSA:1.25.40.10 33 197 1.6E-10 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS06930 c46c2a0bfc26c8bdd8bd686dc56f89b8 114 SUPERFAMILY SSF56935 8 113 1.53E-7 T 22-04-2016 HRM2_RS06930 c46c2a0bfc26c8bdd8bd686dc56f89b8 114 Gene3D G3DSA:2.40.170.20 2 104 2.2E-7 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 HRM2_RS09170 148ec360ab09d1f4be302a49525b2cf2 562 Gene3D G3DSA:3.40.190.10 183 428 5.7E-38 T 22-04-2016 HRM2_RS09170 148ec360ab09d1f4be302a49525b2cf2 562 SUPERFAMILY SSF53850 53 502 9.66E-59 T 22-04-2016 HRM2_RS09170 148ec360ab09d1f4be302a49525b2cf2 562 PIRSF PIRSF035859 2 561 1.3E-282 T 22-04-2016 IPR014597 ABC transporter, periplasmic substrate-binding protein GO:0005215 HRM2_RS09170 148ec360ab09d1f4be302a49525b2cf2 562 Gene3D G3DSA:3.40.190.10 68 182 4.5E-11 T 22-04-2016 HRM2_RS09170 148ec360ab09d1f4be302a49525b2cf2 562 Pfam PF01547 Bacterial extracellular solute-binding protein 68 405 6.1E-11 T 22-04-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 HRM2_RS09170 148ec360ab09d1f4be302a49525b2cf2 562 PANTHER PTHR30061 70 522 1.0E-16 T 22-04-2016 HRM2_RS16170 1f86c83b696b79739ec55569c54f7432 295 Pfam PF08668 HDOD domain 24 220 1.7E-52 T 22-04-2016 IPR013976 Metal-dependent hydrolase HDOD HRM2_RS16170 1f86c83b696b79739ec55569c54f7432 295 SUPERFAMILY SSF109604 15 282 2.08E-62 T 22-04-2016 HRM2_RS16170 1f86c83b696b79739ec55569c54f7432 295 Gene3D G3DSA:1.10.3150.10 8 285 2.3E-71 T 22-04-2016 IPR013976 Metal-dependent hydrolase HDOD HRM2_RS16170 1f86c83b696b79739ec55569c54f7432 295 PANTHER PTHR33525:SF3 24 295 1.5E-55 T 22-04-2016 HRM2_RS16170 1f86c83b696b79739ec55569c54f7432 295 PANTHER PTHR33525 24 295 1.5E-55 T 22-04-2016 HRM2_RS02605 9a91239ca3ec0e8c155c398a4273e332 266 PANTHER PTHR30566 17 253 4.8E-48 T 22-04-2016 HRM2_RS02605 9a91239ca3ec0e8c155c398a4273e332 266 SUPERFAMILY SSF50182 96 160 2.65E-12 T 22-04-2016 IPR010920 LSM domain HRM2_RS02605 9a91239ca3ec0e8c155c398a4273e332 266 PANTHER PTHR30566:SF11 17 253 4.8E-48 T 22-04-2016 HRM2_RS02605 9a91239ca3ec0e8c155c398a4273e332 266 Pfam PF00924 Mechanosensitive ion channel 55 250 1.5E-33 T 22-04-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 HRM2_RS02605 9a91239ca3ec0e8c155c398a4273e332 266 Gene3D G3DSA:2.30.30.60 112 160 5.7E-12 T 22-04-2016 HRM2_RS08760 2fb88e10c2bdb303ddc66928125c6c8f 203 PANTHER PTHR30055 5 184 2.4E-22 T 22-04-2016 HRM2_RS08760 2fb88e10c2bdb303ddc66928125c6c8f 203 Gene3D G3DSA:1.10.357.10 11 182 4.2E-28 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HRM2_RS08760 2fb88e10c2bdb303ddc66928125c6c8f 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 5.5E-15 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS08760 2fb88e10c2bdb303ddc66928125c6c8f 203 SUPERFAMILY SSF46689 11 79 1.42E-17 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS08760 2fb88e10c2bdb303ddc66928125c6c8f 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 1.9E-9 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS08760 2fb88e10c2bdb303ddc66928125c6c8f 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 1.9E-9 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS02915 8bb54d4b1511f33ae50904819b4d690f 222 Pfam PF07796 Protein of unknown function (DUF1638) 31 197 2.3E-38 T 22-04-2016 IPR012437 Domain of unknown function DUF1638 HRM2_RS06925 2e67177ab8538c3fc0d3ce88209f73f4 99 Pfam PF14026 Protein of unknown function (DUF4242) 7 77 1.9E-12 T 22-04-2016 IPR025336 Protein of unknown function DUF4242 HRM2_RS10030 90aca47eb98a85e22bcc0be5ef6bf15e 307 Pfam PF07589 PEP-CTERM motif 281 304 4.6E-7 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain HRM2_RS10030 90aca47eb98a85e22bcc0be5ef6bf15e 307 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 282 306 4.1E-5 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain HRM2_RS07600 9416c24c622eab590816382414bb09eb 219 SUPERFAMILY SSF46785 4 72 2.49E-14 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS07600 9416c24c622eab590816382414bb09eb 219 Pfam PF07729 FCD domain 79 209 1.1E-19 T 22-04-2016 IPR011711 GntR, C-terminal HRM2_RS07600 9416c24c622eab590816382414bb09eb 219 Gene3D G3DSA:1.10.10.10 3 68 8.7E-17 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS07600 9416c24c622eab590816382414bb09eb 219 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 4.48E-5 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS07600 9416c24c622eab590816382414bb09eb 219 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 4.48E-5 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS07600 9416c24c622eab590816382414bb09eb 219 Gene3D G3DSA:1.20.120.530 72 215 1.4E-23 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS07600 9416c24c622eab590816382414bb09eb 219 PANTHER PTHR11751 11 94 1.4E-16 T 22-04-2016 HRM2_RS07600 9416c24c622eab590816382414bb09eb 219 SMART SM00345 10 68 2.3E-7 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS07600 9416c24c622eab590816382414bb09eb 219 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 68 9.0E-13 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HRM2_RS07600 9416c24c622eab590816382414bb09eb 219 SMART SM00895 78 210 2.0E-17 T 22-04-2016 IPR011711 GntR, C-terminal HRM2_RS07600 9416c24c622eab590816382414bb09eb 219 SUPERFAMILY SSF48008 73 215 2.88E-21 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal HRM2_RS07910 caf4d6df351010d8c5e366b7c9f3f927 490 Pfam PF06253 Trimethylamine methyltransferase (MTTB) 11 472 1.3E-103 T 22-04-2016 IPR010426 Trimethylamine methyltransferase GO:0008168|GO:0015948 KEGG: 00680+2.1.1.250|MetaCyc: PWY-5250|UniPathway: UPA00645 HRM2_RS03655 31431d4c463b5c5b6b63c42679a160b8 499 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 53 492 2.6E-128 T 22-04-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 HRM2_RS03655 31431d4c463b5c5b6b63c42679a160b8 499 PANTHER PTHR30047 10 493 7.2E-160 T 22-04-2016 HRM2_RS03655 31431d4c463b5c5b6b63c42679a160b8 499 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 14 492 2.6E-158 T 22-04-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 HRM2_RS03655 31431d4c463b5c5b6b63c42679a160b8 499 ProSitePatterns PS01303 BCCT family of transporters signature. 317 326 - T 22-04-2016 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 HRM2_RS03655 31431d4c463b5c5b6b63c42679a160b8 499 PANTHER PTHR30047:SF2 10 493 7.2E-160 T 22-04-2016 HRM2_RS20135 5f9b8760a53e1a28e431643198326bd9 471 SUPERFAMILY SSF51735 165 463 7.55E-32 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS20135 5f9b8760a53e1a28e431643198326bd9 471 SUPERFAMILY SSF55961 16 143 5.79E-14 T 22-04-2016 HRM2_RS20135 5f9b8760a53e1a28e431643198326bd9 471 Pfam PF01370 NAD dependent epimerase/dehydratase family 166 377 1.5E-8 T 22-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 HRM2_RS20135 5f9b8760a53e1a28e431643198326bd9 471 Gene3D G3DSA:3.40.50.720 165 410 8.4E-19 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS20135 5f9b8760a53e1a28e431643198326bd9 471 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 166 456 5.7E-88 T 22-04-2016 IPR010099 Epimerase family protein SDR39U1 HRM2_RS20135 5f9b8760a53e1a28e431643198326bd9 471 Pfam PF08338 Domain of unknown function (DUF1731) 413 456 1.1E-12 T 22-04-2016 IPR013549 Domain of unknown function DUF1731 HRM2_RS20135 5f9b8760a53e1a28e431643198326bd9 471 PANTHER PTHR11092 158 465 1.1E-111 T 22-04-2016 IPR010099 Epimerase family protein SDR39U1 HRM2_RS20135 5f9b8760a53e1a28e431643198326bd9 471 PANTHER PTHR11092:SF0 158 465 1.1E-111 T 22-04-2016 HRM2_RS11980 685ab790e5c2b614393ce60da7837773 72 Pfam PF00578 AhpC/TSA family 16 48 8.7E-5 T 22-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 HRM2_RS11980 685ab790e5c2b614393ce60da7837773 72 Gene3D G3DSA:3.40.30.10 15 45 2.7E-4 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS19505 8ffd651d8dc88d7d31d0d093ded46922 232 SUPERFAMILY SSF141130 154 215 1.7E-34 T 22-04-2016 HRM2_RS19505 8ffd651d8dc88d7d31d0d093ded46922 232 SUPERFAMILY SSF141130 2 124 1.7E-34 T 22-04-2016 HRM2_RS19505 8ffd651d8dc88d7d31d0d093ded46922 232 Pfam PF03069 Acetamidase/Formamidase family 46 213 5.8E-34 T 22-04-2016 IPR004304 Acetamidase/Formamidase GO:0016811 HRM2_RS19505 8ffd651d8dc88d7d31d0d093ded46922 232 Gene3D G3DSA:2.60.120.580 1 107 5.3E-27 T 22-04-2016 HRM2_RS07615 1f9e5a9f2046d7690025556d948a23ea 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 47 216 2.9E-15 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS07615 1f9e5a9f2046d7690025556d948a23ea 222 PANTHER PTHR30614 1 222 6.5E-77 T 22-04-2016 HRM2_RS07615 1f9e5a9f2046d7690025556d948a23ea 222 Gene3D G3DSA:1.10.3720.10 13 216 2.6E-43 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS07615 1f9e5a9f2046d7690025556d948a23ea 222 SUPERFAMILY SSF161098 15 202 1.83E-43 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS07615 1f9e5a9f2046d7690025556d948a23ea 222 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 111 4.4E-30 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HRM2_RS14100 ccfde3e6e153a41f66de6c68ed7a491d 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 285 2.9E-18 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS14100 ccfde3e6e153a41f66de6c68ed7a491d 293 PANTHER PTHR30425 1 292 1.8E-52 T 22-04-2016 HRM2_RS14100 ccfde3e6e153a41f66de6c68ed7a491d 293 SUPERFAMILY SSF161098 18 282 9.16E-28 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS14100 ccfde3e6e153a41f66de6c68ed7a491d 293 Gene3D G3DSA:1.10.3720.10 15 286 4.7E-32 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS09805 ec8e506261d1d476e70bc98c031cb2a0 277 TIGRFAM TIGR04178 exo_archaeo: exosortase/archaeosortase family protein 178 269 2.9E-21 T 22-04-2016 IPR026392 Exosortase/Archaeosortase domain HRM2_RS09805 ec8e506261d1d476e70bc98c031cb2a0 277 Pfam PF09721 Transmembrane exosortase (Exosortase_EpsH) 19 269 2.5E-65 T 22-04-2016 IPR019127 Exosortase EpsH-related KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- HRM2_RS09805 ec8e506261d1d476e70bc98c031cb2a0 277 TIGRFAM TIGR02602 8TM_EpsH: exosortase 34 267 1.8E-61 T 22-04-2016 IPR013426 Exosortase, EpsH HRM2_RS13145 8ceab9af5a93cc62caa8eca3938852d8 204 Gene3D G3DSA:3.40.50.300 1 196 1.2E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13145 8ceab9af5a93cc62caa8eca3938852d8 204 Pfam PF00005 ABC transporter 18 150 1.9E-20 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS13145 8ceab9af5a93cc62caa8eca3938852d8 204 SUPERFAMILY SSF52540 2 195 1.05E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS13145 8ceab9af5a93cc62caa8eca3938852d8 204 PANTHER PTHR24220 3 193 9.0E-50 T 22-04-2016 HRM2_RS13145 8ceab9af5a93cc62caa8eca3938852d8 204 SMART SM00382 26 198 4.4E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS23720 3be83d5b2d69771de3ce4658e0e5daa6 102 Pfam PF12728 Helix-turn-helix domain 49 99 2.9E-6 T 22-04-2016 HRM2_RS05585 d5846f195d89d06db2b8497fe5b62993 653 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 44 625 4.4E-158 T 22-04-2016 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 HRM2_RS05585 d5846f195d89d06db2b8497fe5b62993 653 Pfam PF03958 Bacterial type II/III secretion system short domain 141 199 2.3E-6 T 22-04-2016 IPR005644 NolW-like HRM2_RS05585 d5846f195d89d06db2b8497fe5b62993 653 Pfam PF03958 Bacterial type II/III secretion system short domain 206 276 6.3E-9 T 22-04-2016 IPR005644 NolW-like HRM2_RS05585 d5846f195d89d06db2b8497fe5b62993 653 Pfam PF03958 Bacterial type II/III secretion system short domain 284 361 1.2E-15 T 22-04-2016 IPR005644 NolW-like HRM2_RS05585 d5846f195d89d06db2b8497fe5b62993 653 PANTHER PTHR30332 30 640 3.2E-104 T 22-04-2016 HRM2_RS05585 d5846f195d89d06db2b8497fe5b62993 653 PANTHER PTHR30332:SF8 30 640 3.2E-104 T 22-04-2016 HRM2_RS05585 d5846f195d89d06db2b8497fe5b62993 653 Pfam PF00263 Bacterial type II and III secretion system protein 451 618 2.9E-51 T 22-04-2016 IPR004846 Type II/III secretion system GO:0009306 HRM2_RS05585 d5846f195d89d06db2b8497fe5b62993 653 PRINTS PR00811 Bacterial general secretion pathway protein D signature 582 600 4.8E-22 T 22-04-2016 IPR001775 GspD/PilQ family HRM2_RS05585 d5846f195d89d06db2b8497fe5b62993 653 PRINTS PR00811 Bacterial general secretion pathway protein D signature 362 372 4.8E-22 T 22-04-2016 IPR001775 GspD/PilQ family HRM2_RS05585 d5846f195d89d06db2b8497fe5b62993 653 PRINTS PR00811 Bacterial general secretion pathway protein D signature 482 492 4.8E-22 T 22-04-2016 IPR001775 GspD/PilQ family HRM2_RS05585 d5846f195d89d06db2b8497fe5b62993 653 PRINTS PR00811 Bacterial general secretion pathway protein D signature 447 471 4.8E-22 T 22-04-2016 IPR001775 GspD/PilQ family HRM2_RS05585 d5846f195d89d06db2b8497fe5b62993 653 PRINTS PR00811 Bacterial general secretion pathway protein D signature 605 619 4.8E-22 T 22-04-2016 IPR001775 GspD/PilQ family HRM2_RS03145 f78c1b04acdd71e857b4f50c01ec46e1 326 SUPERFAMILY SSF53098 62 320 2.73E-18 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS03145 f78c1b04acdd71e857b4f50c01ec46e1 326 Pfam PF13546 DDE superfamily endonuclease 66 255 2.8E-14 T 22-04-2016 HRM2_RS15485 939dedb26d64363278351fe775702fdd 324 Pfam PF01875 Memo-like protein 36 315 4.7E-33 T 22-04-2016 IPR002737 MEMO1 family HRM2_RS15485 939dedb26d64363278351fe775702fdd 324 PANTHER PTHR11060:SF0 30 321 2.2E-17 T 22-04-2016 HRM2_RS15485 939dedb26d64363278351fe775702fdd 324 PANTHER PTHR11060 30 321 2.2E-17 T 22-04-2016 IPR002737 MEMO1 family HRM2_RS15485 939dedb26d64363278351fe775702fdd 324 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 35 317 1.4E-58 T 22-04-2016 IPR002737 MEMO1 family HRM2_RS24340 6e4fbb84f1f62f7ed73928f46fd36270 306 PANTHER PTHR30465 1 305 6.3E-147 T 22-04-2016 HRM2_RS24340 6e4fbb84f1f62f7ed73928f46fd36270 306 PANTHER PTHR30465:SF67 1 305 6.3E-147 T 22-04-2016 HRM2_RS24340 6e4fbb84f1f62f7ed73928f46fd36270 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 303 7.3E-30 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS24340 6e4fbb84f1f62f7ed73928f46fd36270 306 SUPERFAMILY SSF161098 87 289 3.14E-26 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS24340 6e4fbb84f1f62f7ed73928f46fd36270 306 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 14 63 6.7E-10 T 22-04-2016 IPR025966 Oligopeptide transport permease C-like, N-terminal domain HRM2_RS24340 6e4fbb84f1f62f7ed73928f46fd36270 306 Gene3D G3DSA:1.10.3720.10 86 301 3.8E-26 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS12675 8e760bfa5525d2042b97a7e2efed3bf8 353 Pfam PF04892 VanZ like family 210 340 1.4E-9 T 22-04-2016 IPR006976 VanZ-like HRM2_RS12675 8e760bfa5525d2042b97a7e2efed3bf8 353 Gene3D G3DSA:2.60.120.260 58 165 2.6E-5 T 22-04-2016 IPR008979 Galactose-binding domain-like HRM2_RS12700 085c6fe574ce0314c1609071bbc25daf 614 SUPERFAMILY SSF52540 357 609 6.07E-73 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12700 085c6fe574ce0314c1609071bbc25daf 614 Gene3D G3DSA:3.40.50.300 365 603 4.8E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12700 085c6fe574ce0314c1609071bbc25daf 614 Gene3D G3DSA:1.20.1560.10 32 311 3.3E-20 T 22-04-2016 HRM2_RS12700 085c6fe574ce0314c1609071bbc25daf 614 SUPERFAMILY SSF90123 20 322 1.44E-27 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HRM2_RS12700 085c6fe574ce0314c1609071bbc25daf 614 SMART SM00382 394 591 9.2E-14 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS12700 085c6fe574ce0314c1609071bbc25daf 614 PANTHER PTHR24221 76 613 1.8E-147 T 22-04-2016 HRM2_RS12700 085c6fe574ce0314c1609071bbc25daf 614 PANTHER PTHR24221 14 60 1.8E-147 T 22-04-2016 HRM2_RS12700 085c6fe574ce0314c1609071bbc25daf 614 Pfam PF00005 ABC transporter 385 538 7.3E-32 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS12700 085c6fe574ce0314c1609071bbc25daf 614 Pfam PF00664 ABC transporter transmembrane region 33 309 2.5E-8 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HRM2_RS12700 085c6fe574ce0314c1609071bbc25daf 614 PANTHER PTHR24221:SF157 76 613 1.8E-147 T 22-04-2016 HRM2_RS12700 085c6fe574ce0314c1609071bbc25daf 614 PANTHER PTHR24221:SF157 14 60 1.8E-147 T 22-04-2016 HRM2_RS11520 13905f35e5e8f5a9ea244fc74cc2e73d 203 PANTHER PTHR34229 2 196 1.8E-40 T 22-04-2016 HRM2_RS11520 13905f35e5e8f5a9ea244fc74cc2e73d 203 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 194 3.0E-50 T 22-04-2016 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 UniPathway: UPA00148 HRM2_RS11520 13905f35e5e8f5a9ea244fc74cc2e73d 203 PANTHER PTHR34229:SF1 2 196 1.8E-40 T 22-04-2016 HRM2_RS10675 de57765138dbe3ddc51f8b9466b2678d 282 SUPERFAMILY SSF161098 76 264 2.88E-28 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS10675 de57765138dbe3ddc51f8b9466b2678d 282 PANTHER PTHR30465:SF57 1 282 4.2E-120 T 22-04-2016 HRM2_RS10675 de57765138dbe3ddc51f8b9466b2678d 282 PANTHER PTHR30465 1 282 4.2E-120 T 22-04-2016 HRM2_RS10675 de57765138dbe3ddc51f8b9466b2678d 282 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 6 58 2.3E-13 T 22-04-2016 IPR025966 Oligopeptide transport permease C-like, N-terminal domain HRM2_RS10675 de57765138dbe3ddc51f8b9466b2678d 282 Gene3D G3DSA:1.10.3720.10 74 279 2.3E-24 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS10675 de57765138dbe3ddc51f8b9466b2678d 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 281 9.8E-27 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS24270 5da8f88d5001deac8cd31451e84e6c58 643 Pfam PF04326 Putative DNA-binding domain 12 140 3.1E-11 T 22-04-2016 IPR007421 Schlafen, AAA domain GO:0005524 HRM2_RS24270 5da8f88d5001deac8cd31451e84e6c58 643 SUPERFAMILY SSF46785 422 499 3.73E-7 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS24270 5da8f88d5001deac8cd31451e84e6c58 643 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 328 405 1.1E-8 T 22-04-2016 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain HRM2_RS24270 5da8f88d5001deac8cd31451e84e6c58 643 Gene3D G3DSA:1.10.10.10 428 499 4.1E-6 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS12645 314f616969b0657c6972bc4a2be810da 291 Pfam PF00535 Glycosyl transferase family 2 59 161 1.6E-11 T 22-04-2016 IPR001173 Glycosyltransferase 2-like HRM2_RS12645 314f616969b0657c6972bc4a2be810da 291 PANTHER PTHR15046:SF4 47 272 5.2E-31 T 22-04-2016 HRM2_RS12645 314f616969b0657c6972bc4a2be810da 291 SUPERFAMILY SSF53448 56 279 1.31E-22 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS12645 314f616969b0657c6972bc4a2be810da 291 PANTHER PTHR15046 47 272 5.2E-31 T 22-04-2016 HRM2_RS12645 314f616969b0657c6972bc4a2be810da 291 Gene3D G3DSA:3.90.550.10 58 166 1.6E-13 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS09560 1d7d43b072193bd33b7f3b8f0e12eeb2 96 Pfam PF01807 CHC2 zinc finger 9 89 2.9E-6 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS09560 1d7d43b072193bd33b7f3b8f0e12eeb2 96 SUPERFAMILY SSF57783 6 91 7.14E-13 T 22-04-2016 HRM2_RS09560 1d7d43b072193bd33b7f3b8f0e12eeb2 96 Gene3D G3DSA:3.90.580.10 5 91 2.3E-13 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HRM2_RS00825 3541703c41a998b9bcb8c350a3e1d623 138 PANTHER PTHR11717:SF18 1 138 1.1E-31 T 22-04-2016 HRM2_RS00825 3541703c41a998b9bcb8c350a3e1d623 138 SUPERFAMILY SSF52788 1 137 7.33E-34 T 22-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily HRM2_RS00825 3541703c41a998b9bcb8c350a3e1d623 138 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 136 7.5E-18 T 22-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily HRM2_RS00825 3541703c41a998b9bcb8c350a3e1d623 138 SMART SM00226 2 138 2.5E-34 T 22-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily HRM2_RS00825 3541703c41a998b9bcb8c350a3e1d623 138 PANTHER PTHR11717 1 138 1.1E-31 T 22-04-2016 HRM2_RS00825 3541703c41a998b9bcb8c350a3e1d623 138 Gene3D G3DSA:3.40.50.270 1 137 2.5E-35 T 22-04-2016 HRM2_RS09545 51c2a90b1c044ec12010ac5b004a4802 307 Pfam PF08535 KorB domain 116 193 1.7E-5 T 22-04-2016 IPR013741 Transcriptional repressor protein KorB HRM2_RS09545 51c2a90b1c044ec12010ac5b004a4802 307 SUPERFAMILY SSF110849 4 80 4.19E-5 T 22-04-2016 IPR003115 ParB/Sulfiredoxin HRM2_RS14875 f673fa438699d1bbd10ec62bfe9885db 761 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 145 738 1.1E-125 T 22-04-2016 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 HRM2_RS14875 f673fa438699d1bbd10ec62bfe9885db 761 PRINTS PR00811 Bacterial general secretion pathway protein D signature 693 711 6.3E-16 T 22-04-2016 IPR001775 GspD/PilQ family HRM2_RS14875 f673fa438699d1bbd10ec62bfe9885db 761 PRINTS PR00811 Bacterial general secretion pathway protein D signature 558 582 6.3E-16 T 22-04-2016 IPR001775 GspD/PilQ family HRM2_RS14875 f673fa438699d1bbd10ec62bfe9885db 761 PRINTS PR00811 Bacterial general secretion pathway protein D signature 500 510 6.3E-16 T 22-04-2016 IPR001775 GspD/PilQ family HRM2_RS14875 f673fa438699d1bbd10ec62bfe9885db 761 PRINTS PR00811 Bacterial general secretion pathway protein D signature 716 730 6.3E-16 T 22-04-2016 IPR001775 GspD/PilQ family HRM2_RS14875 f673fa438699d1bbd10ec62bfe9885db 761 Pfam PF03958 Bacterial type II/III secretion system short domain 384 500 4.8E-8 T 22-04-2016 IPR005644 NolW-like HRM2_RS14875 f673fa438699d1bbd10ec62bfe9885db 761 Pfam PF00263 Bacterial type II and III secretion system protein 562 728 7.0E-49 T 22-04-2016 IPR004846 Type II/III secretion system GO:0009306 HRM2_RS14875 f673fa438699d1bbd10ec62bfe9885db 761 PANTHER PTHR30332 142 738 2.2E-71 T 22-04-2016 HRM2_RS12085 f43a9f4e381602d98be7fcd44c04688b 184 PANTHER PTHR30574 1 183 3.7E-13 T 22-04-2016 HRM2_RS12085 f43a9f4e381602d98be7fcd44c04688b 184 PANTHER PTHR30574:SF1 1 183 3.7E-13 T 22-04-2016 HRM2_RS12085 f43a9f4e381602d98be7fcd44c04688b 184 Pfam PF04143 Sulphur transport 28 169 3.8E-12 T 22-04-2016 IPR007272 Sulphur transport domain HRM2_RS12680 1bc36c6d82ebde959c2d221168ba2d76 302 SUPERFAMILY SSF53795 150 204 8.24E-11 T 22-04-2016 HRM2_RS12680 1bc36c6d82ebde959c2d221168ba2d76 302 Gene3D G3DSA:3.40.50.300 148 206 3.5E-12 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08045 0f3a58aa4bd91287e3ebd63c93373c52 664 SUPERFAMILY SSF56935 34 664 1.95E-102 T 22-04-2016 HRM2_RS08045 0f3a58aa4bd91287e3ebd63c93373c52 664 Pfam PF07715 TonB-dependent Receptor Plug Domain 50 151 6.0E-21 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 HRM2_RS08045 0f3a58aa4bd91287e3ebd63c93373c52 664 Pfam PF00593 TonB dependent receptor 434 663 1.1E-28 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 HRM2_RS08045 0f3a58aa4bd91287e3ebd63c93373c52 664 PANTHER PTHR32552:SF0 43 664 3.9E-45 T 22-04-2016 HRM2_RS08045 0f3a58aa4bd91287e3ebd63c93373c52 664 Gene3D G3DSA:2.170.130.10 34 157 1.7E-27 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 HRM2_RS08045 0f3a58aa4bd91287e3ebd63c93373c52 664 PANTHER PTHR32552 43 664 3.9E-45 T 22-04-2016 HRM2_RS08045 0f3a58aa4bd91287e3ebd63c93373c52 664 Gene3D G3DSA:2.40.170.20 158 664 3.6E-79 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 HRM2_RS11815 179288a16d397af06b169592550c2921 328 Pfam PF03116 NQR2, RnfD, RnfE family 19 326 1.4E-102 T 22-04-2016 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 HRM2_RS11815 179288a16d397af06b169592550c2921 328 PANTHER PTHR30578 17 326 5.9E-87 T 22-04-2016 HRM2_RS11815 179288a16d397af06b169592550c2921 328 TIGRFAM TIGR01946 rnfD: electron transport complex, RnfABCDGE type, D subunit 22 326 3.4E-87 T 22-04-2016 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 HRM2_RS11815 179288a16d397af06b169592550c2921 328 PANTHER PTHR30578:SF0 17 326 5.9E-87 T 22-04-2016 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 HRM2_RS11815 179288a16d397af06b169592550c2921 328 Hamap MF_00462 Electron transport complex subunit RsxD [rsxD]. 17 328 23.925 T 22-04-2016 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 HRM2_RS21105 f8bead71fc3a74e8ef3b804418527284 318 PANTHER PTHR11002 84 301 1.9E-57 T 22-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 HRM2_RS21105 f8bead71fc3a74e8ef3b804418527284 318 PANTHER PTHR11002:SF17 84 301 1.9E-57 T 22-04-2016 HRM2_RS21105 f8bead71fc3a74e8ef3b804418527284 318 Pfam PF00484 Carbonic anhydrase 128 282 1.0E-33 T 22-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 HRM2_RS21105 f8bead71fc3a74e8ef3b804418527284 318 Gene3D G3DSA:3.40.1050.10 78 290 1.1E-45 T 22-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 HRM2_RS21105 f8bead71fc3a74e8ef3b804418527284 318 SMART SM00947 121 286 4.9E-40 T 22-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 HRM2_RS21105 f8bead71fc3a74e8ef3b804418527284 318 SUPERFAMILY SSF53056 83 289 1.83E-47 T 22-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 HRM2_RS08050 9cbbe0a96217b26a3d7152e553061603 296 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 40 284 2.6E-43 T 22-04-2016 HRM2_RS08050 9cbbe0a96217b26a3d7152e553061603 296 SUPERFAMILY SSF53850 49 242 4.41E-19 T 22-04-2016 HRM2_RS08050 9cbbe0a96217b26a3d7152e553061603 296 Gene3D G3DSA:3.40.190.10 126 249 2.7E-7 T 22-04-2016 HRM2_RS16920 b26d74a20b903b190ed354d8c6e4b325 72 PANTHER PTHR24423 1 69 7.2E-13 T 22-04-2016 HRM2_RS16920 b26d74a20b903b190ed354d8c6e4b325 72 Pfam PF00072 Response regulator receiver domain 1 59 5.9E-8 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS16920 b26d74a20b903b190ed354d8c6e4b325 72 PANTHER PTHR24423:SF544 1 69 7.2E-13 T 22-04-2016 HRM2_RS16920 b26d74a20b903b190ed354d8c6e4b325 72 SUPERFAMILY SSF52172 1 67 3.42E-11 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS16920 b26d74a20b903b190ed354d8c6e4b325 72 Gene3D G3DSA:3.40.50.2300 1 67 1.6E-13 T 22-04-2016 HRM2_RS24280 d668d1f6fd1fdfb1bb9d1256b09682a5 672 Pfam PF02384 N-6 DNA Methylase 535 646 2.4E-5 T 22-04-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 HRM2_RS24280 d668d1f6fd1fdfb1bb9d1256b09682a5 672 Pfam PF02384 N-6 DNA Methylase 296 477 1.8E-15 T 22-04-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 HRM2_RS24280 d668d1f6fd1fdfb1bb9d1256b09682a5 672 PANTHER PTHR30195 298 473 1.3E-21 T 22-04-2016 HRM2_RS24280 d668d1f6fd1fdfb1bb9d1256b09682a5 672 PANTHER PTHR30195 494 641 1.3E-21 T 22-04-2016 HRM2_RS24280 d668d1f6fd1fdfb1bb9d1256b09682a5 672 PANTHER PTHR30195:SF2 298 473 1.3E-21 T 22-04-2016 HRM2_RS24280 d668d1f6fd1fdfb1bb9d1256b09682a5 672 PANTHER PTHR30195:SF2 494 641 1.3E-21 T 22-04-2016 HRM2_RS24280 d668d1f6fd1fdfb1bb9d1256b09682a5 672 Gene3D G3DSA:3.40.50.150 321 466 9.7E-42 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS24280 d668d1f6fd1fdfb1bb9d1256b09682a5 672 Gene3D G3DSA:3.40.50.150 514 631 9.7E-42 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS24280 d668d1f6fd1fdfb1bb9d1256b09682a5 672 SUPERFAMILY SSF53335 164 468 2.43E-52 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS24280 d668d1f6fd1fdfb1bb9d1256b09682a5 672 SUPERFAMILY SSF53335 520 670 2.43E-52 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS24280 d668d1f6fd1fdfb1bb9d1256b09682a5 672 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 362 376 5.0E-13 T 22-04-2016 HRM2_RS24280 d668d1f6fd1fdfb1bb9d1256b09682a5 672 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 450 462 5.0E-13 T 22-04-2016 HRM2_RS24280 d668d1f6fd1fdfb1bb9d1256b09682a5 672 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 531 555 5.0E-13 T 22-04-2016 HRM2_RS24280 d668d1f6fd1fdfb1bb9d1256b09682a5 672 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 319 335 5.0E-13 T 22-04-2016 HRM2_RS05860 deee7f563a08ea51abb13714b2dfc44b 58 PANTHER PTHR10742:SF263 8 58 7.6E-26 T 22-04-2016 HRM2_RS05860 deee7f563a08ea51abb13714b2dfc44b 58 Pfam PF12831 FAD dependent oxidoreductase 8 45 4.7E-9 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS05860 deee7f563a08ea51abb13714b2dfc44b 58 PANTHER PTHR10742 8 58 7.6E-26 T 22-04-2016 HRM2_RS05860 deee7f563a08ea51abb13714b2dfc44b 58 Gene3D G3DSA:3.50.50.60 8 56 3.7E-18 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HRM2_RS05860 deee7f563a08ea51abb13714b2dfc44b 58 SUPERFAMILY SSF51971 8 55 7.89E-11 T 22-04-2016 HRM2_RS23730 1269cc636cb33bed101d33bc376814a1 560 PANTHER PTHR30153 38 186 3.8E-31 T 22-04-2016 HRM2_RS23730 1269cc636cb33bed101d33bc376814a1 560 Pfam PF00772 DnaB-like helicase N terminal domain 57 154 3.0E-28 T 22-04-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 HRM2_RS23730 1269cc636cb33bed101d33bc376814a1 560 Gene3D G3DSA:1.10.860.10 57 154 8.8E-30 T 22-04-2016 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal HRM2_RS23730 1269cc636cb33bed101d33bc376814a1 560 Pfam PF13481 AAA domain 213 393 1.8E-35 T 22-04-2016 HRM2_RS23730 1269cc636cb33bed101d33bc376814a1 560 SUPERFAMILY SSF48024 57 162 3.27E-28 T 22-04-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 HRM2_RS23730 1269cc636cb33bed101d33bc376814a1 560 Gene3D G3DSA:3.40.50.300 217 471 3.6E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23730 1269cc636cb33bed101d33bc376814a1 560 SUPERFAMILY SSF52540 228 400 9.71E-10 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08615 892c2adbcd789d6cf53b6aa4e78a1efd 180 Pfam PF04231 Endonuclease I 16 180 1.1E-29 T 22-04-2016 IPR007346 Endonuclease I GO:0004518 HRM2_RS08615 892c2adbcd789d6cf53b6aa4e78a1efd 180 PANTHER PTHR33607:SF2 71 180 7.6E-17 T 22-04-2016 HRM2_RS08615 892c2adbcd789d6cf53b6aa4e78a1efd 180 SUPERFAMILY SSF54060 9 179 8.83E-53 T 22-04-2016 HRM2_RS08615 892c2adbcd789d6cf53b6aa4e78a1efd 180 PANTHER PTHR33607 71 180 7.6E-17 T 22-04-2016 HRM2_RS02050 088c280ab31a65a75a52cc174180f646 221 Gene3D G3DSA:3.40.50.1240 4 198 1.2E-42 T 22-04-2016 IPR029033 Histidine phosphatase superfamily HRM2_RS02050 088c280ab31a65a75a52cc174180f646 221 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 198 9.7E-30 T 22-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 HRM2_RS02050 088c280ab31a65a75a52cc174180f646 221 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 8 17 - T 22-04-2016 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 UniPathway: UPA00109 HRM2_RS02050 088c280ab31a65a75a52cc174180f646 221 PANTHER PTHR23029:SF26 3 206 3.6E-59 T 22-04-2016 HRM2_RS02050 088c280ab31a65a75a52cc174180f646 221 SUPERFAMILY SSF53254 5 202 3.14E-39 T 22-04-2016 IPR029033 Histidine phosphatase superfamily HRM2_RS02050 088c280ab31a65a75a52cc174180f646 221 PANTHER PTHR23029 3 206 3.6E-59 T 22-04-2016 HRM2_RS02050 088c280ab31a65a75a52cc174180f646 221 SMART SM00855 5 167 7.6E-13 T 22-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 HRM2_RS01355 ed6d14c6a771e3dfb264c4da317e924b 401 Pfam PF02653 Branched-chain amino acid transport system / permease component 113 378 8.4E-47 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 HRM2_RS01355 ed6d14c6a771e3dfb264c4da317e924b 401 PANTHER PTHR30482:SF9 61 392 1.0E-122 T 22-04-2016 HRM2_RS01355 ed6d14c6a771e3dfb264c4da317e924b 401 PANTHER PTHR30482 61 392 1.0E-122 T 22-04-2016 HRM2_RS18140 627de3218fa07659f27c852efa76dc66 318 Gene3D G3DSA:3.40.50.150 106 266 3.9E-23 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS18140 627de3218fa07659f27c852efa76dc66 318 SUPERFAMILY SSF53335 103 267 5.63E-27 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS18140 627de3218fa07659f27c852efa76dc66 318 Pfam PF13489 Methyltransferase domain 119 260 9.0E-19 T 22-04-2016 HRM2_RS13390 734432d7d67142dfb58dd3a0435686eb 252 Hamap MF_00991 Futalosine hydrolase [mqnB]. 18 243 20.688 T 22-04-2016 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374|UniPathway: UPA00079 HRM2_RS13390 734432d7d67142dfb58dd3a0435686eb 252 SUPERFAMILY SSF53167 4 232 4.59E-27 T 22-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HRM2_RS13390 734432d7d67142dfb58dd3a0435686eb 252 Pfam PF01048 Phosphorylase superfamily 4 238 3.7E-24 T 22-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HRM2_RS13390 734432d7d67142dfb58dd3a0435686eb 252 TIGRFAM TIGR03664 fut_nucase: futalosine hydrolase 5 239 5.1E-44 T 22-04-2016 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374|UniPathway: UPA00079 HRM2_RS13390 734432d7d67142dfb58dd3a0435686eb 252 Gene3D G3DSA:3.40.50.1580 3 244 2.3E-40 T 22-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HRM2_RS12725 82f8ac480c9809a5c85ea3036665a4d5 776 Pfam PF04932 O-Antigen ligase 240 382 1.2E-21 T 22-04-2016 IPR007016 O-antigen ligase-related HRM2_RS12725 82f8ac480c9809a5c85ea3036665a4d5 776 SUPERFAMILY SSF48452 524 770 8.85E-21 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS12725 82f8ac480c9809a5c85ea3036665a4d5 776 Pfam PF13181 Tetratricopeptide repeat 738 766 0.038 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS12725 82f8ac480c9809a5c85ea3036665a4d5 776 PANTHER PTHR23083 527 632 9.7E-23 T 22-04-2016 HRM2_RS12725 82f8ac480c9809a5c85ea3036665a4d5 776 PANTHER PTHR23083 658 774 9.7E-23 T 22-04-2016 HRM2_RS12725 82f8ac480c9809a5c85ea3036665a4d5 776 SMART SM00028 662 695 420.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS12725 82f8ac480c9809a5c85ea3036665a4d5 776 SMART SM00028 734 767 6.4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS12725 82f8ac480c9809a5c85ea3036665a4d5 776 SMART SM00028 700 733 420.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS12725 82f8ac480c9809a5c85ea3036665a4d5 776 SMART SM00028 535 568 0.61 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HRM2_RS12725 82f8ac480c9809a5c85ea3036665a4d5 776 Gene3D G3DSA:1.25.40.10 521 774 3.0E-27 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS06790 e6df2aa29d2846794d6dd5068b94bc92 389 SUPERFAMILY SSF56796 3 381 6.15E-98 T 22-04-2016 HRM2_RS06790 e6df2aa29d2846794d6dd5068b94bc92 389 Gene3D G3DSA:1.20.1090.10 183 380 3.9E-40 T 22-04-2016 HRM2_RS06790 e6df2aa29d2846794d6dd5068b94bc92 389 Gene3D G3DSA:3.40.50.1970 2 182 6.6E-53 T 22-04-2016 HRM2_RS06790 e6df2aa29d2846794d6dd5068b94bc92 389 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 376 1.6E-100 T 22-04-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 HRM2_RS06790 e6df2aa29d2846794d6dd5068b94bc92 389 PANTHER PTHR11496 1 389 2.2E-89 T 22-04-2016 HRM2_RS04595 51667fe852bed1959b8fd3633dfe78f8 124 Gene3D G3DSA:1.10.10.10 47 112 4.5E-4 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS04595 51667fe852bed1959b8fd3633dfe78f8 124 Pfam PF08279 HTH domain 51 103 8.5E-5 T 22-04-2016 IPR013196 Helix-turn-helix, type 11 HRM2_RS00480 81e6e34938a8056b6a61ed205ecc2490 320 PANTHER PTHR30024 10 277 6.9E-13 T 22-04-2016 HRM2_RS00480 81e6e34938a8056b6a61ed205ecc2490 320 SUPERFAMILY SSF53850 46 316 1.66E-21 T 22-04-2016 HRM2_RS00480 81e6e34938a8056b6a61ed205ecc2490 320 Pfam PF09084 NMT1/THI5 like 58 201 1.2E-4 T 22-04-2016 IPR015168 SsuA/THI5-like HRM2_RS14815 f55feaf2a715b256f3d8cf861fca58cd 277 PANTHER PTHR30413 19 277 9.2E-57 T 22-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 HRM2_RS14815 f55feaf2a715b256f3d8cf861fca58cd 277 Pfam PF01061 ABC-2 type transporter 25 236 4.9E-28 T 22-04-2016 IPR013525 ABC-2 type transporter GO:0016020 HRM2_RS14815 f55feaf2a715b256f3d8cf861fca58cd 277 PANTHER PTHR30413:SF8 19 277 9.2E-57 T 22-04-2016 HRM2_RS14815 f55feaf2a715b256f3d8cf861fca58cd 277 PRINTS PR00164 ABC-2 type transport system membrane protein signature 158 182 4.8E-7 T 22-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 HRM2_RS14815 f55feaf2a715b256f3d8cf861fca58cd 277 PRINTS PR00164 ABC-2 type transport system membrane protein signature 45 66 4.8E-7 T 22-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 HRM2_RS14815 f55feaf2a715b256f3d8cf861fca58cd 277 PRINTS PR00164 ABC-2 type transport system membrane protein signature 195 214 4.8E-7 T 22-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 HRM2_RS17285 ebb83deed0305cb3d8f35ad3c6f4e6e9 155 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 20 150 3.6E-22 T 22-04-2016 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component HRM2_RS17285 ebb83deed0305cb3d8f35ad3c6f4e6e9 155 PANTHER PTHR35011 1 151 6.6E-14 T 22-04-2016 HRM2_RS04445 39dfc2d396f24c513d66f0e632e5c579 277 Pfam PF13482 RNase_H superfamily 87 236 6.5E-34 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS04445 39dfc2d396f24c513d66f0e632e5c579 277 Gene3D G3DSA:3.30.420.10 86 257 2.7E-22 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS04445 39dfc2d396f24c513d66f0e632e5c579 277 PANTHER PTHR38462 2 262 2.7E-53 T 22-04-2016 HRM2_RS04445 39dfc2d396f24c513d66f0e632e5c579 277 SUPERFAMILY SSF53098 86 245 1.63E-34 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS04715 1d55dd4fdbe46b182c3722af9f91ca6e 448 PANTHER PTHR21337 4 447 9.0E-259 T 22-04-2016 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 HRM2_RS04715 1d55dd4fdbe46b182c3722af9f91ca6e 448 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 7 447 3.6E-205 T 22-04-2016 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 HRM2_RS04715 1d55dd4fdbe46b182c3722af9f91ca6e 448 Pfam PF01474 Class-II DAHP synthetase family 7 443 6.3E-196 T 22-04-2016 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 HRM2_RS04715 1d55dd4fdbe46b182c3722af9f91ca6e 448 SUPERFAMILY SSF51569 4 447 3.37E-190 T 22-04-2016 HRM2_RS09745 c1ad5458395b6ae81917860d85bd6adc 261 SUPERFAMILY SSF52172 139 258 2.13E-15 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS09745 c1ad5458395b6ae81917860d85bd6adc 261 Gene3D G3DSA:3.40.50.2300 138 260 6.1E-17 T 22-04-2016 HRM2_RS09745 c1ad5458395b6ae81917860d85bd6adc 261 Pfam PF00072 Response regulator receiver domain 142 253 1.7E-9 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS09745 c1ad5458395b6ae81917860d85bd6adc 261 SMART SM00448 140 253 7.7E-4 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS11760 53c8a1886f92ebae7e2e32ee72373672 857 Pfam PF02687 FtsX-like permease family 264 373 4.8E-9 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 HRM2_RS11760 53c8a1886f92ebae7e2e32ee72373672 857 Pfam PF02687 FtsX-like permease family 737 851 1.1E-8 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 HRM2_RS11760 53c8a1886f92ebae7e2e32ee72373672 857 PANTHER PTHR30287 1 834 6.5E-71 T 22-04-2016 HRM2_RS20540 3b1b731fccbf025f4af805620e960b17 485 SUPERFAMILY SSF53756 202 404 2.13E-10 T 22-04-2016 HRM2_RS20540 3b1b731fccbf025f4af805620e960b17 485 Pfam PF00534 Glycosyl transferases group 1 273 400 3.8E-8 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 HRM2_RS02515 3a2bf3d82fbe4c4a96290ac4a705cd5b 305 SUPERFAMILY SSF64182 3 300 6.1E-10 T 22-04-2016 HRM2_RS15445 e360f3300a135ca98c80ac68f80e0f49 165 Pfam PF03477 ATP cone domain 50 136 6.1E-20 T 22-04-2016 IPR005144 ATP-cone domain HRM2_RS15445 e360f3300a135ca98c80ac68f80e0f49 165 PANTHER PTHR30455:SF2 2 156 7.3E-69 T 22-04-2016 HRM2_RS15445 e360f3300a135ca98c80ac68f80e0f49 165 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 157 79.519 T 22-04-2016 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 HRM2_RS15445 e360f3300a135ca98c80ac68f80e0f49 165 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 147 8.0E-59 T 22-04-2016 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 HRM2_RS15445 e360f3300a135ca98c80ac68f80e0f49 165 PANTHER PTHR30455 2 156 7.3E-69 T 22-04-2016 HRM2_RS12300 93d9ace57327fb5ed2be146c2fb3db28 390 PANTHER PTHR30480 21 389 4.5E-120 T 22-04-2016 HRM2_RS12300 93d9ace57327fb5ed2be146c2fb3db28 390 PIRSF PIRSF016719 2 390 2.8E-128 T 22-04-2016 IPR008302 Uncharacterised conserved protein UCP016719 HRM2_RS12300 93d9ace57327fb5ed2be146c2fb3db28 390 Pfam PF07075 Protein of unknown function (DUF1343) 25 389 3.5E-125 T 22-04-2016 IPR008302 Uncharacterised conserved protein UCP016719 HRM2_RS12300 93d9ace57327fb5ed2be146c2fb3db28 390 PANTHER PTHR30480:SF3 21 389 4.5E-120 T 22-04-2016 HRM2_RS10895 0e7ee8f7faaa90c838b1a3fe5ba993ca 207 Gene3D G3DSA:3.10.450.50 124 177 7.8E-16 T 22-04-2016 IPR032710 NTF2-like domain HRM2_RS10895 0e7ee8f7faaa90c838b1a3fe5ba993ca 207 Gene3D G3DSA:3.10.450.50 30 73 7.8E-16 T 22-04-2016 IPR032710 NTF2-like domain HRM2_RS10895 0e7ee8f7faaa90c838b1a3fe5ba993ca 207 Pfam PF05494 MlaC protein 36 202 6.1E-32 T 22-04-2016 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC HRM2_RS10895 0e7ee8f7faaa90c838b1a3fe5ba993ca 207 Gene3D G3DSA:1.10.10.640 74 114 1.3E-11 T 22-04-2016 IPR023094 Toluene tolerance protein, alpha-helical HRM2_RS10895 0e7ee8f7faaa90c838b1a3fe5ba993ca 207 Gene3D G3DSA:1.10.10.640 178 207 1.3E-11 T 22-04-2016 IPR023094 Toluene tolerance protein, alpha-helical HRM2_RS10895 0e7ee8f7faaa90c838b1a3fe5ba993ca 207 PANTHER PTHR36573 1 186 1.0E-19 T 22-04-2016 HRM2_RS02070 f54349da4fb59e75027a9b9069428ca3 480 SMART SM00248 88 117 46.0 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 HRM2_RS02070 f54349da4fb59e75027a9b9069428ca3 480 SMART SM00248 337 370 620.0 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 HRM2_RS02070 f54349da4fb59e75027a9b9069428ca3 480 SMART SM00248 232 261 3300.0 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 HRM2_RS02070 f54349da4fb59e75027a9b9069428ca3 480 SMART SM00248 53 82 0.038 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 HRM2_RS02070 f54349da4fb59e75027a9b9069428ca3 480 SMART SM00248 262 292 3600.0 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 HRM2_RS02070 f54349da4fb59e75027a9b9069428ca3 480 SMART SM00248 138 169 3100.0 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 HRM2_RS02070 f54349da4fb59e75027a9b9069428ca3 480 Gene3D G3DSA:1.25.40.20 237 342 6.5E-13 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain HRM2_RS02070 f54349da4fb59e75027a9b9069428ca3 480 Gene3D G3DSA:1.25.40.20 53 125 6.5E-13 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain HRM2_RS02070 f54349da4fb59e75027a9b9069428ca3 480 Pfam PF13637 Ankyrin repeats (many copies) 56 109 3.7E-5 T 22-04-2016 HRM2_RS02070 f54349da4fb59e75027a9b9069428ca3 480 SUPERFAMILY SSF48403 237 296 1.87E-11 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain HRM2_RS02070 f54349da4fb59e75027a9b9069428ca3 480 SUPERFAMILY SSF48403 51 125 1.87E-11 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain HRM2_RS06025 cc13f842819c6cf109dffbe53ef1022c 255 Pfam PF00005 ABC transporter 25 170 7.8E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS06025 cc13f842819c6cf109dffbe53ef1022c 255 PANTHER PTHR24220 11 215 2.6E-66 T 22-04-2016 HRM2_RS06025 cc13f842819c6cf109dffbe53ef1022c 255 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS06025 cc13f842819c6cf109dffbe53ef1022c 255 Gene3D G3DSA:3.40.50.300 8 216 5.4E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06025 cc13f842819c6cf109dffbe53ef1022c 255 SMART SM00382 34 239 2.0E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS06025 cc13f842819c6cf109dffbe53ef1022c 255 SUPERFAMILY SSF52540 7 215 1.17E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23080 1ddd2f642281b716d02f557fa1fc5913 272 Pfam PF04060 Putative Fe-S cluster 13 44 3.4E-12 T 22-04-2016 IPR007202 4Fe-4S domain GO:0051536 HRM2_RS23080 1ddd2f642281b716d02f557fa1fc5913 272 Pfam PF12654 Domain of unknown function (DUF3786) 91 268 3.1E-40 T 22-04-2016 IPR024264 Domain of unknown function DUF3786 HRM2_RS24275 51648c631895c4fdc3f22360d42ae506 527 SUPERFAMILY SSF116734 281 425 2.62E-18 T 22-04-2016 HRM2_RS24275 51648c631895c4fdc3f22360d42ae506 527 SUPERFAMILY SSF116734 66 232 1.46E-13 T 22-04-2016 HRM2_RS24275 51648c631895c4fdc3f22360d42ae506 527 Pfam PF01420 Type I restriction modification DNA specificity domain 335 424 9.5E-5 T 22-04-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 HRM2_RS09660 3ea44d5948f5e91d5cc803c9e18b032d 128 Pfam PF11171 Protein of unknown function (DUF2958) 28 94 5.0E-8 T 22-04-2016 IPR021341 Protein of unknown function DUF2958 HRM2_RS06490 5ecadff7a27980005614ad940feebd4f 455 PANTHER PTHR23073:SF24 244 446 4.6E-44 T 22-04-2016 HRM2_RS06490 5ecadff7a27980005614ad940feebd4f 455 SUPERFAMILY SSF52540 209 442 6.98E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06490 5ecadff7a27980005614ad940feebd4f 455 PANTHER PTHR23073 244 446 4.6E-44 T 22-04-2016 HRM2_RS06490 5ecadff7a27980005614ad940feebd4f 455 SMART SM00382 246 378 4.0E-14 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS06490 5ecadff7a27980005614ad940feebd4f 455 Gene3D G3DSA:3.40.50.300 216 410 3.6E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS06490 5ecadff7a27980005614ad940feebd4f 455 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 251 375 1.5E-28 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HRM2_RS08475 3465c2e5c788488875330d9144991acc 62 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 13 41 5.0E-4 T 22-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 HRM2_RS08475 3465c2e5c788488875330d9144991acc 62 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 2 55 11.628 T 22-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 HRM2_RS08475 3465c2e5c788488875330d9144991acc 62 Pfam PF01165 Ribosomal protein S21 2 55 2.0E-15 T 22-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 HRM2_RS08475 3465c2e5c788488875330d9144991acc 62 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 55 1.7E-15 T 22-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 HRM2_RS08080 c44ddd3d994d0e176a2ef5c705c07404 117 SUPERFAMILY SSF52540 7 70 2.4E-11 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS08080 c44ddd3d994d0e176a2ef5c705c07404 117 PANTHER PTHR24221:SF138 7 62 1.0E-16 T 22-04-2016 HRM2_RS08080 c44ddd3d994d0e176a2ef5c705c07404 117 PANTHER PTHR24221 7 62 1.0E-16 T 22-04-2016 HRM2_RS08080 c44ddd3d994d0e176a2ef5c705c07404 117 Gene3D G3DSA:3.40.50.300 8 70 3.7E-9 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS03680 d6262c994dafa1a76958ba3d823e2b80 515 Pfam PF12770 CHAT domain 324 511 1.3E-12 T 22-04-2016 IPR024983 CHAT domain HRM2_RS11350 f7af8eeea756d75f98b03448590a929f 125 Pfam PF01844 HNH endonuclease 39 87 2.2E-11 T 22-04-2016 IPR002711 HNH endonuclease GO:0003676|GO:0004519 HRM2_RS11350 f7af8eeea756d75f98b03448590a929f 125 SMART SM00507 27 82 1.0E-6 T 22-04-2016 IPR003615 HNH nuclease HRM2_RS15110 84d94d8651d7d6c89c24d4e79386aee4 95 PRINTS PR00297 10kDa chaperonin signature 25 46 6.9E-31 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HRM2_RS15110 84d94d8651d7d6c89c24d4e79386aee4 95 PRINTS PR00297 10kDa chaperonin signature 3 18 6.9E-31 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HRM2_RS15110 84d94d8651d7d6c89c24d4e79386aee4 95 PRINTS PR00297 10kDa chaperonin signature 60 72 6.9E-31 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HRM2_RS15110 84d94d8651d7d6c89c24d4e79386aee4 95 PRINTS PR00297 10kDa chaperonin signature 81 94 6.9E-31 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HRM2_RS15110 84d94d8651d7d6c89c24d4e79386aee4 95 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 22-04-2016 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 HRM2_RS15110 84d94d8651d7d6c89c24d4e79386aee4 95 SMART SM00883 2 94 1.5E-53 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HRM2_RS15110 84d94d8651d7d6c89c24d4e79386aee4 95 Gene3D G3DSA:2.30.33.40 2 95 2.7E-39 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HRM2_RS15110 84d94d8651d7d6c89c24d4e79386aee4 95 PANTHER PTHR10772 1 95 2.2E-45 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HRM2_RS15110 84d94d8651d7d6c89c24d4e79386aee4 95 Pfam PF00166 Chaperonin 10 Kd subunit 3 94 1.1E-34 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HRM2_RS15110 84d94d8651d7d6c89c24d4e79386aee4 95 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 26.434 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HRM2_RS15110 84d94d8651d7d6c89c24d4e79386aee4 95 SUPERFAMILY SSF50129 1 95 5.53E-35 T 22-04-2016 IPR011032 GroES-like HRM2_RS20760 b3049c1dfe0d7257a79d325c45a48300 134 Gene3D G3DSA:1.10.260.40 6 45 1.0E-7 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS20760 b3049c1dfe0d7257a79d325c45a48300 134 SUPERFAMILY SSF47413 5 50 8.45E-8 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HRM2_RS11840 fe22e58bcc03a9db736f83a15815bb26 91 Gene3D G3DSA:3.40.1080.10 10 88 2.0E-16 T 22-04-2016 HRM2_RS11840 fe22e58bcc03a9db736f83a15815bb26 91 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 9 59 1.8E-7 T 22-04-2016 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 HRM2_RS11840 fe22e58bcc03a9db736f83a15815bb26 91 SUPERFAMILY SSF100950 7 72 7.03E-10 T 22-04-2016 HRM2_RS17350 b7c0682d87d9040ceec4836566ba2dbb 88 Pfam PF06005 Protein of unknown function (DUF904) 21 83 3.6E-8 T 22-04-2016 IPR009252 Cell division protein ZapB GO:0000917|GO:0005737|GO:0043093 HRM2_RS03835 ab8bd8ad0c232c29c071c6451b960176 211 Pfam PF03358 NADPH-dependent FMN reductase 2 159 3.8E-28 T 22-04-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 HRM2_RS03835 ab8bd8ad0c232c29c071c6451b960176 211 Gene3D G3DSA:3.40.50.360 2 184 8.1E-37 T 22-04-2016 IPR029039 Flavoprotein-like domain HRM2_RS03835 ab8bd8ad0c232c29c071c6451b960176 211 SUPERFAMILY SSF52218 2 190 6.06E-40 T 22-04-2016 IPR029039 Flavoprotein-like domain HRM2_RS03835 ab8bd8ad0c232c29c071c6451b960176 211 PANTHER PTHR10204:SF43 1 194 1.2E-84 T 22-04-2016 HRM2_RS03835 ab8bd8ad0c232c29c071c6451b960176 211 PANTHER PTHR10204 1 194 1.2E-84 T 22-04-2016 HRM2_RS02815 85f91bd70573aba66ca6746c3ca98784 452 Pfam PF02321 Outer membrane efflux protein 43 221 2.8E-25 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS02815 85f91bd70573aba66ca6746c3ca98784 452 Pfam PF02321 Outer membrane efflux protein 249 438 1.3E-27 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS02815 85f91bd70573aba66ca6746c3ca98784 452 Gene3D G3DSA:1.20.1600.10 41 439 2.1E-68 T 22-04-2016 HRM2_RS02815 85f91bd70573aba66ca6746c3ca98784 452 SUPERFAMILY SSF56954 11 439 1.44E-75 T 22-04-2016 HRM2_RS02815 85f91bd70573aba66ca6746c3ca98784 452 PANTHER PTHR30203 43 440 2.8E-48 T 22-04-2016 HRM2_RS23005 53c6b2a24786db998daa26d84190f41a 351 Gene3D G3DSA:2.40.100.10 180 298 6.8E-7 T 22-04-2016 IPR029000 Cyclophilin-like domain HRM2_RS23005 53c6b2a24786db998daa26d84190f41a 351 PANTHER PTHR18866 151 351 5.1E-30 T 22-04-2016 HRM2_RS23005 53c6b2a24786db998daa26d84190f41a 351 SUPERFAMILY SSF50891 179 294 1.21E-9 T 22-04-2016 IPR029000 Cyclophilin-like domain HRM2_RS23005 53c6b2a24786db998daa26d84190f41a 351 Pfam PF02626 Allophanate hydrolase subunit 2 26 287 3.8E-84 T 22-04-2016 IPR003778 Carboxyltransferase domain, subdomain A and B HRM2_RS23005 53c6b2a24786db998daa26d84190f41a 351 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 7 310 1.0E-88 T 22-04-2016 IPR003778 Carboxyltransferase domain, subdomain A and B HRM2_RS23005 53c6b2a24786db998daa26d84190f41a 351 SMART SM00797 25 304 8.1E-123 T 22-04-2016 IPR003778 Carboxyltransferase domain, subdomain A and B HRM2_RS23005 53c6b2a24786db998daa26d84190f41a 351 PANTHER PTHR18866:SF74 151 351 5.1E-30 T 22-04-2016 HRM2_RS15350 0663fba99dbde15e5b70123e4ff41993 255 PANTHER PTHR24220 4 246 6.2E-78 T 22-04-2016 HRM2_RS15350 0663fba99dbde15e5b70123e4ff41993 255 Pfam PF00005 ABC transporter 23 162 2.1E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS15350 0663fba99dbde15e5b70123e4ff41993 255 Gene3D G3DSA:3.40.50.300 3 207 2.3E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS15350 0663fba99dbde15e5b70123e4ff41993 255 SUPERFAMILY SSF52540 3 236 2.35E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS15350 0663fba99dbde15e5b70123e4ff41993 255 PANTHER PTHR24220:SF589 4 246 6.2E-78 T 22-04-2016 HRM2_RS15350 0663fba99dbde15e5b70123e4ff41993 255 SMART SM00382 32 210 7.5E-14 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS06335 5bae35a51a07b7c1f4703837ca33a295 568 Gene3D G3DSA:3.80.30.20 240 460 2.5E-35 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe HRM2_RS06335 5bae35a51a07b7c1f4703837ca33a295 568 SUPERFAMILY SSF102114 237 557 9.03E-34 T 22-04-2016 HRM2_RS06335 5bae35a51a07b7c1f4703837ca33a295 568 PANTHER PTHR11918 27 175 1.7E-121 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein HRM2_RS06335 5bae35a51a07b7c1f4703837ca33a295 568 PANTHER PTHR11918 424 565 1.7E-121 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein HRM2_RS06335 5bae35a51a07b7c1f4703837ca33a295 568 PANTHER PTHR11918 192 404 1.7E-121 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein HRM2_RS06335 5bae35a51a07b7c1f4703837ca33a295 568 SMART SM00729 238 455 3.3E-29 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HRM2_RS06335 5bae35a51a07b7c1f4703837ca33a295 568 Pfam PF04055 Radical SAM superfamily 242 399 5.6E-14 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS06335 5bae35a51a07b7c1f4703837ca33a295 568 PANTHER PTHR11918:SF46 27 175 1.7E-121 T 22-04-2016 HRM2_RS06335 5bae35a51a07b7c1f4703837ca33a295 568 PANTHER PTHR11918:SF46 424 565 1.7E-121 T 22-04-2016 HRM2_RS06335 5bae35a51a07b7c1f4703837ca33a295 568 PANTHER PTHR11918:SF46 192 404 1.7E-121 T 22-04-2016 HRM2_RS21805 d422c1712cdc60a8f98de99da9148b28 479 Pfam PF06253 Trimethylamine methyltransferase (MTTB) 10 469 2.1E-82 T 22-04-2016 IPR010426 Trimethylamine methyltransferase GO:0008168|GO:0015948 KEGG: 00680+2.1.1.250|MetaCyc: PWY-5250|UniPathway: UPA00645 HRM2_RS13735 ce605e976543818453f57bec057c2e82 539 Pfam PF04932 O-Antigen ligase 187 320 3.7E-11 T 22-04-2016 IPR007016 O-antigen ligase-related HRM2_RS14850 814ab15ece3d762058d5785377efc542 447 Gene3D G3DSA:2.60.40.1120 370 422 3.6E-4 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain HRM2_RS09815 3e29005ae5a70fc05944beb71121b132 128 Pfam PF01850 PIN domain 4 120 1.8E-13 T 22-04-2016 IPR002716 PIN domain HRM2_RS09815 3e29005ae5a70fc05944beb71121b132 128 Gene3D G3DSA:3.40.50.1010 2 125 2.5E-21 T 22-04-2016 IPR029060 PIN domain-like HRM2_RS09815 3e29005ae5a70fc05944beb71121b132 128 SUPERFAMILY SSF88723 2 127 1.18E-22 T 22-04-2016 IPR029060 PIN domain-like HRM2_RS09615 e4f7c91b08ac3c5c04db0bfe218fa334 237 Gene3D G3DSA:3.30.70.1230 44 200 3.7E-11 T 22-04-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 HRM2_RS09615 e4f7c91b08ac3c5c04db0bfe218fa334 237 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 45 202 1.5E-5 T 22-04-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 HRM2_RS09615 e4f7c91b08ac3c5c04db0bfe218fa334 237 SUPERFAMILY SSF55073 43 199 1.57E-20 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS21675 701f68baf9f4c8afe6782e746deaa98c 532 Gene3D G3DSA:3.40.50.720 381 521 1.4E-40 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS21675 701f68baf9f4c8afe6782e746deaa98c 532 Pfam PF00999 Sodium/hydrogen exchanger family 4 346 6.7E-37 T 22-04-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 HRM2_RS21675 701f68baf9f4c8afe6782e746deaa98c 532 PANTHER PTHR16254:SF14 6 522 8.8E-115 T 22-04-2016 HRM2_RS21675 701f68baf9f4c8afe6782e746deaa98c 532 SUPERFAMILY SSF51735 388 518 6.68E-16 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS21675 701f68baf9f4c8afe6782e746deaa98c 532 PANTHER PTHR16254 6 522 8.8E-115 T 22-04-2016 HRM2_RS21675 701f68baf9f4c8afe6782e746deaa98c 532 Pfam PF02254 TrkA-N domain 388 504 7.7E-19 T 22-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 HRM2_RS21225 13b1930bc184c28ac03893c9a7781be5 132 ProSitePatterns PS01328 4-hydroxybenzoyl-CoA thioesterase family active site. 14 31 - T 22-04-2016 IPR008272 4-hydroxybenzoyl-CoA thioesterase, active site GO:0016787 HRM2_RS21225 13b1930bc184c28ac03893c9a7781be5 132 PIRSF PIRSF003230 1 130 1.2E-33 T 22-04-2016 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 HRM2_RS21225 13b1930bc184c28ac03893c9a7781be5 132 SUPERFAMILY SSF54637 8 128 1.58E-28 T 22-04-2016 IPR029069 HotDog domain HRM2_RS21225 13b1930bc184c28ac03893c9a7781be5 132 PANTHER PTHR31793 5 128 1.2E-26 T 22-04-2016 HRM2_RS21225 13b1930bc184c28ac03893c9a7781be5 132 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 14 118 6.5E-22 T 22-04-2016 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 HRM2_RS21225 13b1930bc184c28ac03893c9a7781be5 132 Pfam PF03061 Thioesterase superfamily 24 106 1.1E-10 T 22-04-2016 IPR006683 Thioesterase domain HRM2_RS21225 13b1930bc184c28ac03893c9a7781be5 132 Gene3D G3DSA:3.10.129.10 5 128 3.5E-32 T 22-04-2016 IPR029069 HotDog domain HRM2_RS21225 13b1930bc184c28ac03893c9a7781be5 132 PANTHER PTHR31793:SF9 5 128 1.2E-26 T 22-04-2016 HRM2_RS21110 53462c8cbeb22794c15fc4972d413b12 103 Pfam PF06167 Glucose-regulated metallo-peptidase M90 4 44 1.4E-6 T 22-04-2016 IPR010384 MtfA family HRM2_RS20365 a5a9fa0be4ee2580e980cc927e9994fa 410 SUPERFAMILY SSF56801 14 373 6.02E-35 T 22-04-2016 HRM2_RS20365 a5a9fa0be4ee2580e980cc927e9994fa 410 PANTHER PTHR36932:SF1 5 332 9.4E-47 T 22-04-2016 HRM2_RS20365 a5a9fa0be4ee2580e980cc927e9994fa 410 Gene3D G3DSA:3.30.300.30 320 408 1.0E-7 T 22-04-2016 HRM2_RS20365 a5a9fa0be4ee2580e980cc927e9994fa 410 PANTHER PTHR36932 5 332 9.4E-47 T 22-04-2016 HRM2_RS20365 a5a9fa0be4ee2580e980cc927e9994fa 410 Pfam PF00501 AMP-binding enzyme 151 280 7.4E-13 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS20365 a5a9fa0be4ee2580e980cc927e9994fa 410 Gene3D G3DSA:3.40.50.980 146 242 1.7E-10 T 22-04-2016 HRM2_RS04065 324d1a0c7caec06a439f863f48759fc1 525 PANTHER PTHR23150:SF19 168 279 2.5E-23 T 22-04-2016 HRM2_RS04065 324d1a0c7caec06a439f863f48759fc1 525 PANTHER PTHR23150:SF19 123 149 2.5E-23 T 22-04-2016 HRM2_RS04065 324d1a0c7caec06a439f863f48759fc1 525 PANTHER PTHR23150 168 279 2.5E-23 T 22-04-2016 HRM2_RS04065 324d1a0c7caec06a439f863f48759fc1 525 PANTHER PTHR23150 123 149 2.5E-23 T 22-04-2016 HRM2_RS04065 324d1a0c7caec06a439f863f48759fc1 525 SUPERFAMILY SSF56436 101 280 3.53E-32 T 22-04-2016 IPR016187 C-type lectin fold HRM2_RS04065 324d1a0c7caec06a439f863f48759fc1 525 Gene3D G3DSA:3.90.1580.10 64 281 3.7E-31 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme HRM2_RS04065 324d1a0c7caec06a439f863f48759fc1 525 Pfam PF03781 Sulfatase-modifying factor enzyme 1 107 278 2.0E-23 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme HRM2_RS00170 a7e504fac1732e31bf2be4d831b06dd4 174 Pfam PF04060 Putative Fe-S cluster 122 154 1.3E-10 T 22-04-2016 IPR007202 4Fe-4S domain GO:0051536 HRM2_RS05680 8e254e4923a858271a05ae6272055c22 372 Gene3D G3DSA:3.20.20.370 141 370 7.6E-81 T 22-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 HRM2_RS05680 8e254e4923a858271a05ae6272055c22 372 SUPERFAMILY SSF88713 152 368 2.67E-68 T 22-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 HRM2_RS05680 8e254e4923a858271a05ae6272055c22 372 Pfam PF04748 Divergent polysaccharide deacetylase 156 368 3.1E-73 T 22-04-2016 IPR006837 Protein of unknown function DUF610, YibQ HRM2_RS05680 8e254e4923a858271a05ae6272055c22 372 PANTHER PTHR30105 141 372 4.0E-67 T 22-04-2016 HRM2_RS05820 d911ef2749969f4e6a5e9e5b93675a2b 252 SUPERFAMILY SSF55073 79 144 2.83E-5 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS23395 983b60fe5ffff53bcc6bfdfaa7d4d1da 193 SUPERFAMILY SSF82057 120 191 2.75E-20 T 22-04-2016 HRM2_RS23395 983b60fe5ffff53bcc6bfdfaa7d4d1da 193 Pfam PF08274 PhnA Zinc-Ribbon 12 52 1.4E-6 T 22-04-2016 IPR013987 PhnA protein, N-terminal HRM2_RS23395 983b60fe5ffff53bcc6bfdfaa7d4d1da 193 Pfam PF03831 PhnA domain 127 191 1.1E-24 T 22-04-2016 IPR013988 PhnA protein, C-terminal HRM2_RS23395 983b60fe5ffff53bcc6bfdfaa7d4d1da 193 PANTHER PTHR30305 1 191 2.9E-79 T 22-04-2016 HRM2_RS23395 983b60fe5ffff53bcc6bfdfaa7d4d1da 193 SMART SM00782 6 52 3.2E-20 T 22-04-2016 IPR013991 PhnA protein N-terminal, proteobacterial HRM2_RS23395 983b60fe5ffff53bcc6bfdfaa7d4d1da 193 PANTHER PTHR30305:SF2 1 191 2.9E-79 T 22-04-2016 HRM2_RS23395 983b60fe5ffff53bcc6bfdfaa7d4d1da 193 Gene3D G3DSA:2.30.30.40 125 191 4.0E-22 T 22-04-2016 HRM2_RS20965 e895a4b0503cb28df4d295ed77ed06ed 293 Gene3D G3DSA:3.90.550.10 4 274 6.0E-70 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS20965 e895a4b0503cb28df4d295ed77ed06ed 293 SUPERFAMILY SSF53448 1 268 4.73E-63 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HRM2_RS20965 e895a4b0503cb28df4d295ed77ed06ed 293 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 3 262 1.4E-116 T 22-04-2016 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343 HRM2_RS20965 e895a4b0503cb28df4d295ed77ed06ed 293 PANTHER PTHR22572:SF14 5 286 5.0E-98 T 22-04-2016 HRM2_RS20965 e895a4b0503cb28df4d295ed77ed06ed 293 Pfam PF00483 Nucleotidyl transferase 10 240 2.7E-28 T 22-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 HRM2_RS20965 e895a4b0503cb28df4d295ed77ed06ed 293 PANTHER PTHR22572 5 286 5.0E-98 T 22-04-2016 HRM2_RS22520 82b4bd96b01bface9b4e335f73f73e6f 317 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 317 91.249 T 22-04-2016 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 UniPathway: UPA00148 HRM2_RS22520 82b4bd96b01bface9b4e335f73f73e6f 317 PANTHER PTHR34308 1 317 2.9E-98 T 22-04-2016 HRM2_RS22520 82b4bd96b01bface9b4e335f73f73e6f 317 Pfam PF03186 CobD/Cbib protein 12 299 1.3E-98 T 22-04-2016 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 UniPathway: UPA00148 HRM2_RS22520 82b4bd96b01bface9b4e335f73f73e6f 317 PANTHER PTHR34308:SF1 1 317 2.9E-98 T 22-04-2016 HRM2_RS22520 82b4bd96b01bface9b4e335f73f73e6f 317 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 6 314 7.5E-74 T 22-04-2016 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 UniPathway: UPA00148 HRM2_RS03125 a4f9b49e06364e446062135e50e784e9 594 Pfam PF01609 Transposase DDE domain 154 499 2.2E-5 T 22-04-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 HRM2_RS03125 a4f9b49e06364e446062135e50e784e9 594 Pfam PF14104 Domain of unknown function (DUF4277) 26 118 3.5E-6 T 22-04-2016 IPR025457 Domain of unknown function DUF4277 HRM2_RS21835 a4f9b49e06364e446062135e50e784e9 594 Pfam PF01609 Transposase DDE domain 154 499 2.2E-5 T 22-04-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 HRM2_RS21835 a4f9b49e06364e446062135e50e784e9 594 Pfam PF14104 Domain of unknown function (DUF4277) 26 118 3.5E-6 T 22-04-2016 IPR025457 Domain of unknown function DUF4277 HRM2_RS00855 a4f9b49e06364e446062135e50e784e9 594 Pfam PF01609 Transposase DDE domain 154 499 2.2E-5 T 22-04-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 HRM2_RS00855 a4f9b49e06364e446062135e50e784e9 594 Pfam PF14104 Domain of unknown function (DUF4277) 26 118 3.5E-6 T 22-04-2016 IPR025457 Domain of unknown function DUF4277 HRM2_RS04655 e0dfed05f8b4fc785236f22d18bed5cf 140 Gene3D G3DSA:3.30.1460.10 63 132 5.7E-4 T 22-04-2016 HRM2_RS04655 e0dfed05f8b4fc785236f22d18bed5cf 140 SUPERFAMILY SSF69635 45 128 7.22E-7 T 22-04-2016 HRM2_RS21380 21f6d3f0ab358d00b4a2339832502b8a 159 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 26 154 2.4E-29 T 22-04-2016 IPR005247 YbhB/YbcL HRM2_RS21380 21f6d3f0ab358d00b4a2339832502b8a 159 PANTHER PTHR30289 8 159 1.6E-33 T 22-04-2016 HRM2_RS21380 21f6d3f0ab358d00b4a2339832502b8a 159 Pfam PF01161 Phosphatidylethanolamine-binding protein 21 156 7.6E-34 T 22-04-2016 IPR008914 Phosphatidylethanolamine-binding protein HRM2_RS21380 21f6d3f0ab358d00b4a2339832502b8a 159 Gene3D G3DSA:3.90.280.10 7 158 1.2E-43 T 22-04-2016 IPR008914 Phosphatidylethanolamine-binding protein HRM2_RS21380 21f6d3f0ab358d00b4a2339832502b8a 159 SUPERFAMILY SSF49777 8 158 1.83E-41 T 22-04-2016 IPR008914 Phosphatidylethanolamine-binding protein HRM2_RS06710 5e06e3b2a6a25a05fd056f2e0600a5ef 147 SUPERFAMILY SSF53137 6 129 8.5E-11 T 22-04-2016 HRM2_RS19325 d3db35a0eabcfb08848975d5786e1630 229 Gene3D G3DSA:3.40.50.300 2 228 2.1E-70 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19325 d3db35a0eabcfb08848975d5786e1630 229 SUPERFAMILY SSF52540 3 226 6.12E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19325 d3db35a0eabcfb08848975d5786e1630 229 Pfam PF00005 ABC transporter 24 173 2.8E-33 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS19325 d3db35a0eabcfb08848975d5786e1630 229 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS19325 d3db35a0eabcfb08848975d5786e1630 229 PANTHER PTHR24220 5 225 2.3E-92 T 22-04-2016 HRM2_RS19325 d3db35a0eabcfb08848975d5786e1630 229 SMART SM00382 32 219 1.2E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS18900 c24420694f5db9c9c4b0352bb0a921a4 497 Pfam PF00939 Sodium:sulfate symporter transmembrane region 29 471 9.6E-40 T 22-04-2016 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 HRM2_RS18900 c24420694f5db9c9c4b0352bb0a921a4 497 PANTHER PTHR10283 17 477 4.2E-60 T 22-04-2016 HRM2_RS07540 e53613afed66880efa80b84e341dbed8 438 PANTHER PTHR34856:SF1 17 438 8.9E-166 T 22-04-2016 HRM2_RS07540 e53613afed66880efa80b84e341dbed8 438 PANTHER PTHR34856 17 438 8.9E-166 T 22-04-2016 HRM2_RS07540 e53613afed66880efa80b84e341dbed8 438 Pfam PF03916 Polysulphide reductase, NrfD 55 380 1.6E-22 T 22-04-2016 IPR005614 NrfD family HRM2_RS06805 74231ac70a43a785e17a28e5669370b1 157 Gene3D G3DSA:3.40.50.2300 26 154 1.3E-46 T 22-04-2016 HRM2_RS06805 74231ac70a43a785e17a28e5669370b1 157 SUPERFAMILY SSF52172 27 151 2.85E-41 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS06805 74231ac70a43a785e17a28e5669370b1 157 SMART SM00448 29 145 1.7E-40 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS06805 74231ac70a43a785e17a28e5669370b1 157 Pfam PF00072 Response regulator receiver domain 31 146 7.3E-29 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS06805 74231ac70a43a785e17a28e5669370b1 157 PANTHER PTHR24423 28 154 2.4E-51 T 22-04-2016 HRM2_RS09600 56d8fc563d868a8951626b8171f1c5ba 83 Pfam PF13411 MerR HTH family regulatory protein 5 72 3.8E-13 T 22-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HRM2_RS09600 56d8fc563d868a8951626b8171f1c5ba 83 Gene3D G3DSA:1.10.1660.10 5 68 9.0E-10 T 22-04-2016 HRM2_RS09600 56d8fc563d868a8951626b8171f1c5ba 83 SUPERFAMILY SSF46955 5 68 1.01E-7 T 22-04-2016 IPR009061 Putative DNA-binding domain HRM2_RS08720 7a40d7982da80a56337611aa9d0072cf 357 PANTHER PTHR12064:SF25 3 180 1.5E-38 T 22-04-2016 HRM2_RS08720 7a40d7982da80a56337611aa9d0072cf 357 PANTHER PTHR12064 3 180 1.5E-38 T 22-04-2016 HRM2_RS08720 7a40d7982da80a56337611aa9d0072cf 357 Pfam PF01595 Domain of unknown function DUF21 13 172 5.8E-35 T 22-04-2016 IPR002550 Domain of unknown function DUF21 HRM2_RS03000 634b7c7764e54c07e312af8fa35c5b9d 341 PANTHER PTHR19353 35 302 8.0E-80 T 22-04-2016 HRM2_RS03000 634b7c7764e54c07e312af8fa35c5b9d 341 Pfam PF00487 Fatty acid desaturase 69 312 2.8E-33 T 22-04-2016 IPR005804 Fatty acid desaturase domain GO:0006629 HRM2_RS03000 634b7c7764e54c07e312af8fa35c5b9d 341 PANTHER PTHR19353:SF27 35 302 8.0E-80 T 22-04-2016 HRM2_RS24190 3d94025debd7b9f6e489daeb35241e70 195 PANTHER PTHR23501 1 177 1.4E-20 T 22-04-2016 HRM2_RS24190 3d94025debd7b9f6e489daeb35241e70 195 Pfam PF07690 Major Facilitator Superfamily 11 186 8.1E-25 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS24190 3d94025debd7b9f6e489daeb35241e70 195 Gene3D G3DSA:1.20.1250.20 5 186 4.4E-29 T 22-04-2016 HRM2_RS24190 3d94025debd7b9f6e489daeb35241e70 195 SUPERFAMILY SSF103473 4 185 1.96E-30 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS01500 127d09780c8aa7fef19d626661b1197b 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 22-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 HRM2_RS01500 127d09780c8aa7fef19d626661b1197b 252 PANTHER PTHR24322 13 142 1.2E-51 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS01500 127d09780c8aa7fef19d626661b1197b 252 PANTHER PTHR24322 158 189 1.2E-51 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS01500 127d09780c8aa7fef19d626661b1197b 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 3.4E-12 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS01500 127d09780c8aa7fef19d626661b1197b 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 3.4E-12 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS01500 127d09780c8aa7fef19d626661b1197b 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 3.4E-12 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS01500 127d09780c8aa7fef19d626661b1197b 252 Gene3D G3DSA:3.40.50.720 2 252 1.7E-85 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS01500 127d09780c8aa7fef19d626661b1197b 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.1E-42 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS01500 127d09780c8aa7fef19d626661b1197b 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.1E-42 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS01500 127d09780c8aa7fef19d626661b1197b 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.1E-42 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS01500 127d09780c8aa7fef19d626661b1197b 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.1E-42 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS01500 127d09780c8aa7fef19d626661b1197b 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.1E-42 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS01500 127d09780c8aa7fef19d626661b1197b 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.1E-42 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS01500 127d09780c8aa7fef19d626661b1197b 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 250 1.5E-63 T 22-04-2016 HRM2_RS01500 127d09780c8aa7fef19d626661b1197b 252 SUPERFAMILY SSF51735 7 251 3.2E-84 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS07755 df57e40dfeb2b2b122cb8b799ab173ac 495 PANTHER PTHR30203:SF3 9 494 3.2E-104 T 22-04-2016 HRM2_RS07755 df57e40dfeb2b2b122cb8b799ab173ac 495 SUPERFAMILY SSF56954 9 34 3.01E-93 T 22-04-2016 HRM2_RS07755 df57e40dfeb2b2b122cb8b799ab173ac 495 SUPERFAMILY SSF56954 65 477 3.01E-93 T 22-04-2016 HRM2_RS07755 df57e40dfeb2b2b122cb8b799ab173ac 495 Gene3D G3DSA:1.20.1600.10 60 477 1.5E-94 T 22-04-2016 HRM2_RS07755 df57e40dfeb2b2b122cb8b799ab173ac 495 PANTHER PTHR30203 9 494 3.2E-104 T 22-04-2016 HRM2_RS07755 df57e40dfeb2b2b122cb8b799ab173ac 495 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 19 475 6.4E-91 T 22-04-2016 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 HRM2_RS07755 df57e40dfeb2b2b122cb8b799ab173ac 495 Pfam PF02321 Outer membrane efflux protein 295 473 1.1E-21 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS07755 df57e40dfeb2b2b122cb8b799ab173ac 495 Pfam PF02321 Outer membrane efflux protein 76 260 3.1E-18 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS12905 831fdbc24caf6172cf1f41eb696d4cc2 141 PANTHER PTHR31793 3 132 3.0E-24 T 22-04-2016 HRM2_RS12905 831fdbc24caf6172cf1f41eb696d4cc2 141 Gene3D G3DSA:3.10.129.10 5 133 3.3E-34 T 22-04-2016 IPR029069 HotDog domain HRM2_RS12905 831fdbc24caf6172cf1f41eb696d4cc2 141 Pfam PF13279 Thioesterase-like superfamily 15 131 3.7E-14 T 22-04-2016 HRM2_RS12905 831fdbc24caf6172cf1f41eb696d4cc2 141 SUPERFAMILY SSF54637 2 131 9.05E-33 T 22-04-2016 IPR029069 HotDog domain HRM2_RS25240 e36790ec8fbd18f9f37e9d460dc570c4 234 Pfam PF00075 RNase H 104 229 1.6E-24 T 22-04-2016 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 HRM2_RS25240 e36790ec8fbd18f9f37e9d460dc570c4 234 SUPERFAMILY SSF53098 102 230 4.05E-38 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS25240 e36790ec8fbd18f9f37e9d460dc570c4 234 PANTHER PTHR10642 100 231 9.2E-37 T 22-04-2016 HRM2_RS25240 e36790ec8fbd18f9f37e9d460dc570c4 234 Gene3D G3DSA:3.30.420.10 103 231 3.1E-36 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS18280 cc24fe4f89e223d1b979b10d9e463ef7 337 Pfam PF02120 Flagellar hook-length control protein FliK 238 313 5.2E-11 T 22-04-2016 IPR021136 Flagellar hook-length control protein-like, C-terminal HRM2_RS16840 526f67d2b426c01a6c791403a832cc9f 137 Gene3D G3DSA:1.10.357.10 2 119 7.1E-6 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HRM2_RS04105 330ea56bd21cfc3df8815553c26aabb5 232 Gene3D G3DSA:1.25.40.10 136 205 4.1E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS04105 330ea56bd21cfc3df8815553c26aabb5 232 SUPERFAMILY SSF48452 73 208 1.57E-14 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS04105 330ea56bd21cfc3df8815553c26aabb5 232 Gene3D G3DSA:1.25.40.10 25 126 3.0E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS08155 14924271f6239360acef7e8e9b0245cd 147 Gene3D G3DSA:1.10.10.10 9 143 8.6E-31 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS08155 14924271f6239360acef7e8e9b0245cd 147 PANTHER PTHR33164 11 147 1.2E-17 T 22-04-2016 HRM2_RS08155 14924271f6239360acef7e8e9b0245cd 147 Pfam PF01047 MarR family 36 94 1.2E-14 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS08155 14924271f6239360acef7e8e9b0245cd 147 SMART SM00347 29 129 2.6E-12 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS08155 14924271f6239360acef7e8e9b0245cd 147 SUPERFAMILY SSF46785 11 144 3.84E-26 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS08155 14924271f6239360acef7e8e9b0245cd 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 3.9E-5 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS08155 14924271f6239360acef7e8e9b0245cd 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 3.9E-5 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS08155 14924271f6239360acef7e8e9b0245cd 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 3.9E-5 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HRM2_RS12895 046f60a85196ba3435245cf57997149c 252 PANTHER PTHR23054 49 252 1.2E-21 T 22-04-2016 HRM2_RS12895 046f60a85196ba3435245cf57997149c 252 Pfam PF04784 Protein of unknown function, DUF547 76 186 4.4E-28 T 22-04-2016 IPR006869 Domain of unknown function DUF547 HRM2_RS12895 046f60a85196ba3435245cf57997149c 252 PANTHER PTHR23054:SF14 49 252 1.2E-21 T 22-04-2016 HRM2_RS07770 d3e1cdcebceb9e1afa025a79e43ae53b 377 PANTHER PTHR30294 7 375 6.7E-85 T 22-04-2016 HRM2_RS07770 d3e1cdcebceb9e1afa025a79e43ae53b 377 PANTHER PTHR30294:SF17 7 375 6.7E-85 T 22-04-2016 HRM2_RS07770 d3e1cdcebceb9e1afa025a79e43ae53b 377 Pfam PF12698 ABC-2 family transporter protein 28 365 1.6E-41 T 22-04-2016 HRM2_RS04800 213ddd4f090793d9605fb7e0fabc7f83 108 Gene3D G3DSA:3.40.30.10 4 104 5.5E-26 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS04800 213ddd4f090793d9605fb7e0fabc7f83 108 SUPERFAMILY SSF52833 4 104 6.82E-23 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS04800 213ddd4f090793d9605fb7e0fabc7f83 108 PANTHER PTHR11780 5 102 2.6E-15 T 22-04-2016 HRM2_RS04800 213ddd4f090793d9605fb7e0fabc7f83 108 PANTHER PTHR11780:SF12 5 102 2.6E-15 T 22-04-2016 HRM2_RS19490 6d37b0c6c8d597ef54ea538fc0fec7aa 220 Pfam PF13007 Transposase C of IS166 homeodomain 36 108 9.6E-20 T 22-04-2016 IPR024463 Transposase TnpC, homeodomain HRM2_RS19490 6d37b0c6c8d597ef54ea538fc0fec7aa 220 PANTHER PTHR33678 8 220 3.0E-20 T 22-04-2016 HRM2_RS19490 6d37b0c6c8d597ef54ea538fc0fec7aa 220 PANTHER PTHR33678:SF1 8 220 3.0E-20 T 22-04-2016 HRM2_RS19490 6d37b0c6c8d597ef54ea538fc0fec7aa 220 Pfam PF13005 zinc-finger binding domain of transposase IS66 117 159 1.4E-13 T 22-04-2016 IPR024474 Zinc-finger binding domain of transposase IS66 HRM2_RS19490 6d37b0c6c8d597ef54ea538fc0fec7aa 220 Pfam PF03050 Transposase IS66 family 181 220 6.7E-7 T 22-04-2016 IPR004291 Transposase, IS66 HRM2_RS06970 d5effb83e2f5602c893312f9e7a2ad9c 250 Pfam PF02589 Uncharacterised ACR, YkgG family COG1556 54 247 1.9E-31 T 22-04-2016 IPR003741 LUD domain HRM2_RS06970 d5effb83e2f5602c893312f9e7a2ad9c 250 PANTHER PTHR32479:SF11 130 247 5.3E-22 T 22-04-2016 HRM2_RS06970 d5effb83e2f5602c893312f9e7a2ad9c 250 Gene3D G3DSA:3.40.50.10420 53 247 6.0E-43 T 22-04-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain HRM2_RS06970 d5effb83e2f5602c893312f9e7a2ad9c 250 SUPERFAMILY SSF100950 53 247 8.79E-32 T 22-04-2016 HRM2_RS06970 d5effb83e2f5602c893312f9e7a2ad9c 250 PANTHER PTHR32479 130 247 5.3E-22 T 22-04-2016 HRM2_RS22175 a84df36b4d905f113eb847970df45797 134 Pfam PF02085 Class III cytochrome C family 38 130 5.9E-11 T 22-04-2016 IPR020942 Class III cytochrome C GO:0009055|GO:0020037 HRM2_RS22175 a84df36b4d905f113eb847970df45797 134 Gene3D G3DSA:3.90.10.10 38 131 1.3E-11 T 22-04-2016 HRM2_RS22175 a84df36b4d905f113eb847970df45797 134 PRINTS PR00609 Class III cytochrome C signature 123 130 4.0E-5 T 22-04-2016 IPR002322 Cytochrome c, class III GO:0009055|GO:0020037 HRM2_RS22175 a84df36b4d905f113eb847970df45797 134 PRINTS PR00609 Class III cytochrome C signature 56 63 4.0E-5 T 22-04-2016 IPR002322 Cytochrome c, class III GO:0009055|GO:0020037 HRM2_RS22175 a84df36b4d905f113eb847970df45797 134 PRINTS PR00609 Class III cytochrome C signature 104 115 4.0E-5 T 22-04-2016 IPR002322 Cytochrome c, class III GO:0009055|GO:0020037 HRM2_RS22175 a84df36b4d905f113eb847970df45797 134 PRINTS PR00609 Class III cytochrome C signature 44 53 4.0E-5 T 22-04-2016 IPR002322 Cytochrome c, class III GO:0009055|GO:0020037 HRM2_RS22175 a84df36b4d905f113eb847970df45797 134 SUPERFAMILY SSF48695 40 131 3.25E-13 T 22-04-2016 IPR011031 Multihaem cytochrome HRM2_RS15640 7b47c9982935f45d564465e8f39d6d7a 385 PANTHER PTHR34856 2 382 3.8E-95 T 22-04-2016 HRM2_RS15640 7b47c9982935f45d564465e8f39d6d7a 385 PANTHER PTHR34856:SF3 2 382 3.8E-95 T 22-04-2016 HRM2_RS15640 7b47c9982935f45d564465e8f39d6d7a 385 Pfam PF03916 Polysulphide reductase, NrfD 41 335 1.7E-38 T 22-04-2016 IPR005614 NrfD family HRM2_RS23485 660f665f9d0cdd272ab2ea3864f7788d 177 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 41 169 1.7E-27 T 22-04-2016 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component HRM2_RS23485 660f665f9d0cdd272ab2ea3864f7788d 177 PANTHER PTHR35011:SF2 1 171 1.5E-23 T 22-04-2016 HRM2_RS23485 660f665f9d0cdd272ab2ea3864f7788d 177 PANTHER PTHR35011 1 171 1.5E-23 T 22-04-2016 HRM2_RS12570 6bb3ac20e23846ab67f7ea91227dfe61 377 SUPERFAMILY SSF53756 26 374 1.02E-45 T 22-04-2016 HRM2_RS12570 6bb3ac20e23846ab67f7ea91227dfe61 377 Pfam PF00534 Glycosyl transferases group 1 201 345 1.1E-23 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 HRM2_RS12570 6bb3ac20e23846ab67f7ea91227dfe61 377 Gene3D G3DSA:3.40.50.2000 198 342 7.1E-18 T 22-04-2016 HRM2_RS12570 6bb3ac20e23846ab67f7ea91227dfe61 377 PANTHER PTHR12526 202 377 1.1E-27 T 22-04-2016 HRM2_RS12570 6bb3ac20e23846ab67f7ea91227dfe61 377 PANTHER PTHR12526:SF399 202 377 1.1E-27 T 22-04-2016 HRM2_RS00105 0460d097780ed8733e3eb2daa8551815 461 PIRSF PIRSF006603 4 459 6.7E-71 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 HRM2_RS00105 0460d097780ed8733e3eb2daa8551815 461 TIGRFAM TIGR00797 matE: MATE efflux family protein 18 424 4.8E-62 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 HRM2_RS00105 0460d097780ed8733e3eb2daa8551815 461 Pfam PF01554 MatE 246 403 3.7E-24 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 HRM2_RS00105 0460d097780ed8733e3eb2daa8551815 461 Pfam PF01554 MatE 18 176 2.0E-17 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 HRM2_RS00105 0460d097780ed8733e3eb2daa8551815 461 PANTHER PTHR11206 9 457 1.5E-65 T 22-04-2016 HRM2_RS00105 0460d097780ed8733e3eb2daa8551815 461 PANTHER PTHR11206:SF95 9 457 1.5E-65 T 22-04-2016 HRM2_RS20400 4bc88a580bfe3c8c779e88a0bac9b1db 82 Pfam PF17195 Protein of unknown function (DUF5132) 33 77 1.2E-11 T 22-04-2016 IPR033456 Protein of unknown function DUF5132 HRM2_RS02365 a07d528b6f6757f0f54ac354aa54ae80 265 TIGRFAM TIGR00277 HDIG: HDIG domain 35 102 2.8E-7 T 22-04-2016 IPR006675 HDIG domain HRM2_RS02365 a07d528b6f6757f0f54ac354aa54ae80 265 SUPERFAMILY SSF109604 28 164 2.24E-19 T 22-04-2016 HRM2_RS02365 a07d528b6f6757f0f54ac354aa54ae80 265 Gene3D G3DSA:1.10.3210.10 35 152 3.8E-15 T 22-04-2016 IPR006674 HD domain HRM2_RS02365 a07d528b6f6757f0f54ac354aa54ae80 265 Pfam PF01966 HD domain 35 126 9.4E-9 T 22-04-2016 IPR006674 HD domain HRM2_RS21115 05da94f50d179ccc7787a96c15069024 361 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 37 287 2.6E-64 T 22-04-2016 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 HRM2_RS21115 05da94f50d179ccc7787a96c15069024 361 PIRSF PIRSF006470 1 333 7.9E-81 T 22-04-2016 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 HRM2_RS21115 05da94f50d179ccc7787a96c15069024 361 PANTHER PTHR33376 2 336 5.3E-78 T 22-04-2016 HRM2_RS21115 05da94f50d179ccc7787a96c15069024 361 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 37 311 6.2E-77 T 22-04-2016 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 HRM2_RS22320 3b3f5facd0aa44371b2a03a846129bd3 255 Gene3D G3DSA:3.40.50.720 2 248 7.2E-69 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS22320 3b3f5facd0aa44371b2a03a846129bd3 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 1.9E-9 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS22320 3b3f5facd0aa44371b2a03a846129bd3 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.9E-9 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS22320 3b3f5facd0aa44371b2a03a846129bd3 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.9E-9 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS22320 3b3f5facd0aa44371b2a03a846129bd3 255 Pfam PF00106 short chain dehydrogenase 7 204 2.7E-46 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS22320 3b3f5facd0aa44371b2a03a846129bd3 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 7.8E-26 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS22320 3b3f5facd0aa44371b2a03a846129bd3 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 7.8E-26 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS22320 3b3f5facd0aa44371b2a03a846129bd3 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 7.8E-26 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS22320 3b3f5facd0aa44371b2a03a846129bd3 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 7.8E-26 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS22320 3b3f5facd0aa44371b2a03a846129bd3 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 7.8E-26 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS22320 3b3f5facd0aa44371b2a03a846129bd3 255 SUPERFAMILY SSF51735 3 247 3.23E-61 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS22320 3b3f5facd0aa44371b2a03a846129bd3 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 22-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 HRM2_RS22320 3b3f5facd0aa44371b2a03a846129bd3 255 PANTHER PTHR24322 10 145 9.0E-59 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS22320 3b3f5facd0aa44371b2a03a846129bd3 255 PANTHER PTHR24322 161 197 9.0E-59 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS22320 3b3f5facd0aa44371b2a03a846129bd3 255 PANTHER PTHR24322:SF356 10 145 9.0E-59 T 22-04-2016 HRM2_RS22320 3b3f5facd0aa44371b2a03a846129bd3 255 PANTHER PTHR24322:SF356 161 197 9.0E-59 T 22-04-2016 HRM2_RS22320 3b3f5facd0aa44371b2a03a846129bd3 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 200 0.0088 T 22-04-2016 HRM2_RS18230 c5614df88dace2aef6b20ca5df19db66 692 SUPERFAMILY SSF64518 389 441 1.96E-53 T 22-04-2016 HRM2_RS18230 c5614df88dace2aef6b20ca5df19db66 692 SUPERFAMILY SSF64518 1 190 1.96E-53 T 22-04-2016 HRM2_RS18230 c5614df88dace2aef6b20ca5df19db66 692 SUPERFAMILY SSF64518 304 360 1.96E-53 T 22-04-2016 HRM2_RS18230 c5614df88dace2aef6b20ca5df19db66 692 SUPERFAMILY SSF64518 577 692 1.96E-53 T 22-04-2016 HRM2_RS18230 c5614df88dace2aef6b20ca5df19db66 692 SUPERFAMILY SSF64518 220 262 1.96E-53 T 22-04-2016 HRM2_RS18230 c5614df88dace2aef6b20ca5df19db66 692 PANTHER PTHR30244 522 692 3.3E-46 T 22-04-2016 HRM2_RS18230 c5614df88dace2aef6b20ca5df19db66 692 PANTHER PTHR30244 1 187 3.3E-46 T 22-04-2016 HRM2_RS18230 c5614df88dace2aef6b20ca5df19db66 692 Gene3D G3DSA:1.20.1330.10 52 177 3.3E-22 T 22-04-2016 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 HRM2_RS18230 c5614df88dace2aef6b20ca5df19db66 692 Gene3D G3DSA:1.20.1330.10 597 649 3.3E-22 T 22-04-2016 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 HRM2_RS18230 c5614df88dace2aef6b20ca5df19db66 692 PANTHER PTHR30244:SF5 522 692 3.3E-46 T 22-04-2016 HRM2_RS18230 c5614df88dace2aef6b20ca5df19db66 692 PANTHER PTHR30244:SF5 1 187 3.3E-46 T 22-04-2016 HRM2_RS18230 c5614df88dace2aef6b20ca5df19db66 692 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 247 1.4E-43 T 22-04-2016 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 HRM2_RS18230 c5614df88dace2aef6b20ca5df19db66 692 Pfam PF00669 Bacterial flagellin N-terminal helical region 8 138 2.5E-12 T 22-04-2016 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 HRM2_RS18230 c5614df88dace2aef6b20ca5df19db66 692 Pfam PF00700 Bacterial flagellin C-terminal helical region 611 692 1.0E-5 T 22-04-2016 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 HRM2_RS10940 de4ed0e4eeabb79594fda2199de27ca0 66 PANTHER PTHR24960 8 66 2.2E-13 T 22-04-2016 HRM2_RS10940 de4ed0e4eeabb79594fda2199de27ca0 66 PANTHER PTHR24960:SF37 8 66 2.2E-13 T 22-04-2016 HRM2_RS10940 de4ed0e4eeabb79594fda2199de27ca0 66 Pfam PF02662 Methyl-viologen-reducing hydrogenase, delta subunit 8 66 1.2E-26 T 22-04-2016 IPR003813 Methyl-viologen-reducing hydrogenase, delta subunit GO:0015948|GO:0055114 HRM2_RS18385 bb4069b254cd3a94e7d05fc32b18ecf1 451 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 151 361 2.1E-75 T 22-04-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS18385 bb4069b254cd3a94e7d05fc32b18ecf1 451 SMART SM00382 163 345 8.0E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS18385 bb4069b254cd3a94e7d05fc32b18ecf1 451 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 352 361 - T 22-04-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS18385 bb4069b254cd3a94e7d05fc32b18ecf1 451 Gene3D G3DSA:3.40.50.300 99 363 1.6E-97 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18385 bb4069b254cd3a94e7d05fc32b18ecf1 451 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 30 93 8.1E-8 T 22-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS18385 bb4069b254cd3a94e7d05fc32b18ecf1 451 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 14 441 2.9E-168 T 22-04-2016 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS18385 bb4069b254cd3a94e7d05fc32b18ecf1 451 PANTHER PTHR15184 4 441 5.2E-209 T 22-04-2016 HRM2_RS18385 bb4069b254cd3a94e7d05fc32b18ecf1 451 SUPERFAMILY SSF52540 99 366 3.39E-99 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS18385 bb4069b254cd3a94e7d05fc32b18ecf1 451 PANTHER PTHR15184:SF9 4 441 5.2E-209 T 22-04-2016 IPR032463 ATPase, type III secretion system, FliI GO:0016887|GO:0030257|GO:0044780 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HRM2_RS02865 f16d5976384b6a3bb9b4128b6e2924f0 100 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 7 91 3.4E-28 T 22-04-2016 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2 HRM2_RS02865 f16d5976384b6a3bb9b4128b6e2924f0 100 PANTHER PTHR10160 7 93 7.0E-16 T 22-04-2016 HRM2_RS22330 7f50596ceb32bd1979a17a0b03f0eb43 136 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 50 112 9.5E-18 T 22-04-2016 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal HRM2_RS22330 7f50596ceb32bd1979a17a0b03f0eb43 136 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 13 47 6.7E-6 T 22-04-2016 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal HRM2_RS22330 7f50596ceb32bd1979a17a0b03f0eb43 136 SUPERFAMILY SSF50249 7 118 3.77E-27 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS22330 7f50596ceb32bd1979a17a0b03f0eb43 136 PANTHER PTHR34075 7 112 3.9E-21 T 22-04-2016 HRM2_RS24315 4d4bd48df3ff748da203daa6f21898b8 165 Pfam PF00436 Single-strand binding protein family 4 101 7.5E-32 T 22-04-2016 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 HRM2_RS24315 4d4bd48df3ff748da203daa6f21898b8 165 PANTHER PTHR10302 1 165 1.1E-35 T 22-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 HRM2_RS24315 4d4bd48df3ff748da203daa6f21898b8 165 SUPERFAMILY SSF50249 3 165 7.2E-45 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS24315 4d4bd48df3ff748da203daa6f21898b8 165 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 165 8.8E-37 T 22-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 HRM2_RS24315 4d4bd48df3ff748da203daa6f21898b8 165 Gene3D G3DSA:2.40.50.140 1 165 1.2E-41 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS24315 4d4bd48df3ff748da203daa6f21898b8 165 Hamap MF_00984 Single-stranded DNA-binding protein. 4 106 28.307 T 22-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 HRM2_RS23700 bf0c55a350fb8713279124a76f095aca 283 Pfam PF12146 Serine aminopeptidase, S33 35 148 6.5E-14 T 22-04-2016 IPR022742 Serine aminopeptidase, S33 HRM2_RS23700 bf0c55a350fb8713279124a76f095aca 283 SUPERFAMILY SSF53474 7 282 8.19E-34 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS23700 bf0c55a350fb8713279124a76f095aca 283 Gene3D G3DSA:3.40.50.1820 8 282 1.0E-33 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS23990 7d020948836725a32dd07316b3192c77 487 PANTHER PTHR30203:SF3 21 474 2.8E-146 T 22-04-2016 HRM2_RS23990 7d020948836725a32dd07316b3192c77 487 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 17 471 1.5E-109 T 22-04-2016 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 HRM2_RS23990 7d020948836725a32dd07316b3192c77 487 SUPERFAMILY SSF56954 11 37 1.7E-106 T 22-04-2016 HRM2_RS23990 7d020948836725a32dd07316b3192c77 487 SUPERFAMILY SSF56954 64 473 1.7E-106 T 22-04-2016 HRM2_RS23990 7d020948836725a32dd07316b3192c77 487 Gene3D G3DSA:1.20.1600.10 61 473 4.9E-112 T 22-04-2016 HRM2_RS23990 7d020948836725a32dd07316b3192c77 487 Pfam PF02321 Outer membrane efflux protein 288 469 7.1E-19 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS23990 7d020948836725a32dd07316b3192c77 487 Pfam PF02321 Outer membrane efflux protein 75 259 1.1E-24 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS23990 7d020948836725a32dd07316b3192c77 487 PANTHER PTHR30203 21 474 2.8E-146 T 22-04-2016 HRM2_RS21235 b8f2823d95671819d8aaae07731f1270 157 Gene3D G3DSA:3.90.1300.10 37 153 4.0E-24 T 22-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HRM2_RS21235 b8f2823d95671819d8aaae07731f1270 157 SUPERFAMILY SSF75304 39 156 1.83E-26 T 22-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HRM2_RS21235 b8f2823d95671819d8aaae07731f1270 157 Pfam PF01425 Amidase 42 138 1.4E-16 T 22-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HRM2_RS21235 b8f2823d95671819d8aaae07731f1270 157 PANTHER PTHR11895 37 155 2.0E-25 T 22-04-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HRM2_RS19330 7f64a7985a7958c595e41c439501543c 414 Pfam PF02687 FtsX-like permease family 286 407 1.3E-16 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 HRM2_RS19330 7f64a7985a7958c595e41c439501543c 414 Pfam PF12704 MacB-like periplasmic core domain 19 245 1.2E-11 T 22-04-2016 IPR025857 MacB-like periplasmic core domain HRM2_RS19330 7f64a7985a7958c595e41c439501543c 414 PANTHER PTHR30489 4 414 1.5E-44 T 22-04-2016 HRM2_RS01885 4ca3cad1595b68ddb20ae1b97a83324b 451 PANTHER PTHR40269 23 449 1.3E-77 T 22-04-2016 HRM2_RS01885 4ca3cad1595b68ddb20ae1b97a83324b 451 Pfam PF11737 Protein of unknown function (DUF3300) 45 269 1.2E-85 T 22-04-2016 IPR021728 Protein of unknown function DUF3300 HRM2_RS01885 4ca3cad1595b68ddb20ae1b97a83324b 451 PANTHER PTHR40269:SF1 23 449 1.3E-77 T 22-04-2016 HRM2_RS20440 3d3dd5bf31ee401ee7ad4b2e11ecaddd 446 Pfam PF14319 Transposase zinc-binding domain 34 140 9.0E-27 T 22-04-2016 IPR026889 Transposase zinc-binding domain HRM2_RS20440 3d3dd5bf31ee401ee7ad4b2e11ecaddd 446 Pfam PF04986 Putative transposase 167 336 9.4E-22 T 22-04-2016 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 HRM2_RS23935 72a69f711168afa28aed4cd3565d3f0f 357 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 38 355 7.8E-53 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 HRM2_RS23935 72a69f711168afa28aed4cd3565d3f0f 357 PANTHER PTHR30469 7 357 9.0E-55 T 22-04-2016 HRM2_RS23935 72a69f711168afa28aed4cd3565d3f0f 357 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 49 264 9.2E-19 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain HRM2_RS23935 72a69f711168afa28aed4cd3565d3f0f 357 SUPERFAMILY SSF111369 52 263 6.93E-20 T 22-04-2016 HRM2_RS23935 72a69f711168afa28aed4cd3565d3f0f 357 Gene3D G3DSA:2.40.50.100 65 95 2.4E-12 T 22-04-2016 HRM2_RS23935 72a69f711168afa28aed4cd3565d3f0f 357 Gene3D G3DSA:2.40.50.100 170 200 2.4E-12 T 22-04-2016 HRM2_RS22700 8414540dd2906148f4f9546c246de04f 473 Pfam PF06253 Trimethylamine methyltransferase (MTTB) 4 471 1.3E-125 T 22-04-2016 IPR010426 Trimethylamine methyltransferase GO:0008168|GO:0015948 KEGG: 00680+2.1.1.250|MetaCyc: PWY-5250|UniPathway: UPA00645 HRM2_RS22700 8414540dd2906148f4f9546c246de04f 473 PIRSF PIRSF037567 1 473 5.8E-124 T 22-04-2016 IPR010426 Trimethylamine methyltransferase GO:0008168|GO:0015948 KEGG: 00680+2.1.1.250|MetaCyc: PWY-5250|UniPathway: UPA00645 HRM2_RS03940 f3c6df49589c36044323338fd80d7ca4 322 SUPERFAMILY SSF51735 2 311 2.83E-84 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS03940 f3c6df49589c36044323338fd80d7ca4 322 PANTHER PTHR10366:SF323 4 312 4.8E-140 T 22-04-2016 HRM2_RS03940 f3c6df49589c36044323338fd80d7ca4 322 PANTHER PTHR10366 4 312 4.8E-140 T 22-04-2016 HRM2_RS03940 f3c6df49589c36044323338fd80d7ca4 322 Gene3D G3DSA:3.40.50.720 2 170 1.3E-56 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS03940 f3c6df49589c36044323338fd80d7ca4 322 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 301 6.9E-51 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS03940 f3c6df49589c36044323338fd80d7ca4 322 Gene3D G3DSA:3.90.25.10 171 312 1.7E-47 T 22-04-2016 HRM2_RS10650 92f2fd59360937159974cee7e6e08733 434 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 22 430 8.8E-88 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS10650 92f2fd59360937159974cee7e6e08733 434 PIRSF PIRSF006066 6 434 7.3E-85 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 HRM2_RS10650 92f2fd59360937159974cee7e6e08733 434 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 12 425 3.5E-81 T 22-04-2016 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit HRM2_RS10650 92f2fd59360937159974cee7e6e08733 434 PANTHER PTHR33362:SF5 6 430 3.4E-142 T 22-04-2016 HRM2_RS10650 92f2fd59360937159974cee7e6e08733 434 PANTHER PTHR33362 6 430 3.4E-142 T 22-04-2016 HRM2_RS09985 af42b25e39cb43c3523a7b085a94a7a9 430 Pfam PF10996 Beta-Casp domain 233 358 3.4E-25 T 22-04-2016 IPR022712 Beta-Casp domain HRM2_RS09985 af42b25e39cb43c3523a7b085a94a7a9 430 SMART SM00849 13 216 2.3E-17 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS09985 af42b25e39cb43c3523a7b085a94a7a9 430 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 376 428 1.6E-13 T 22-04-2016 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain HRM2_RS09985 af42b25e39cb43c3523a7b085a94a7a9 430 SMART SM01027 232 358 4.8E-48 T 22-04-2016 IPR022712 Beta-Casp domain HRM2_RS09985 af42b25e39cb43c3523a7b085a94a7a9 430 PANTHER PTHR11203 1 428 5.2E-110 T 22-04-2016 HRM2_RS09985 af42b25e39cb43c3523a7b085a94a7a9 430 SUPERFAMILY SSF56281 1 428 6.47E-119 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS09985 af42b25e39cb43c3523a7b085a94a7a9 430 PANTHER PTHR11203:SF11 1 428 5.2E-110 T 22-04-2016 HRM2_RS09985 af42b25e39cb43c3523a7b085a94a7a9 430 Pfam PF00753 Metallo-beta-lactamase superfamily 11 178 2.1E-14 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS09985 af42b25e39cb43c3523a7b085a94a7a9 430 Gene3D G3DSA:3.60.15.10 1 238 6.3E-47 T 22-04-2016 IPR001279 Metallo-beta-lactamase HRM2_RS12335 b8cec2de54d99b26966a7870e33ea847 1184 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 310 741 1.7E-164 T 22-04-2016 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS12335 b8cec2de54d99b26966a7870e33ea847 1184 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 8 1037 0.0 T 22-04-2016 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS12335 b8cec2de54d99b26966a7870e33ea847 1184 PANTHER PTHR32294 4 1164 0.0 T 22-04-2016 HRM2_RS12335 b8cec2de54d99b26966a7870e33ea847 1184 PANTHER PTHR32294:SF0 4 1164 0.0 T 22-04-2016 HRM2_RS12335 b8cec2de54d99b26966a7870e33ea847 1184 Pfam PF14579 Helix-hairpin-helix motif 815 903 6.0E-30 T 22-04-2016 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HRM2_RS12335 b8cec2de54d99b26966a7870e33ea847 1184 SUPERFAMILY SSF89550 8 272 2.55E-34 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 HRM2_RS12335 b8cec2de54d99b26966a7870e33ea847 1184 SUPERFAMILY SSF160975 840 887 4.18E-5 T 22-04-2016 HRM2_RS12335 b8cec2de54d99b26966a7870e33ea847 1184 Gene3D G3DSA:1.10.150.280 840 886 1.2E-7 T 22-04-2016 HRM2_RS12335 b8cec2de54d99b26966a7870e33ea847 1184 Pfam PF02811 PHP domain 10 181 1.0E-47 T 22-04-2016 IPR004013 PHP domain GO:0003824 HRM2_RS12335 b8cec2de54d99b26966a7870e33ea847 1184 SMART SM00481 9 76 3.9E-27 T 22-04-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 HRM2_RS12335 b8cec2de54d99b26966a7870e33ea847 1184 Gene3D G3DSA:3.20.20.140 8 263 1.5E-48 T 22-04-2016 HRM2_RS02705 581c00e4383b0d943fa26fecfb84db4c 221 ProDom PD089226 MA1928 MM0560 MJ0978 76 220 1.0E-22 T 22-04-2016 IPR020209 Uncharacterised protein family, MJ0978 HRM2_RS03505 9e2bb206c085535b8e488dba72a375f6 312 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 5 310 3.5E-51 T 22-04-2016 IPR016833 Putative sodium bile acid cotransporter HRM2_RS03505 9e2bb206c085535b8e488dba72a375f6 312 PANTHER PTHR18640:SF9 41 303 1.3E-35 T 22-04-2016 HRM2_RS03505 9e2bb206c085535b8e488dba72a375f6 312 PANTHER PTHR18640 41 303 1.3E-35 T 22-04-2016 IPR016833 Putative sodium bile acid cotransporter HRM2_RS07215 4d345136da2275801d016d0f03c8f3e3 382 Pfam PF02687 FtsX-like permease family 246 366 2.1E-7 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 HRM2_RS19995 c27cf4645e2a4e201d9832f1d4c21ef1 470 SUPERFAMILY SSF109604 182 274 1.81E-19 T 22-04-2016 HRM2_RS19995 c27cf4645e2a4e201d9832f1d4c21ef1 470 SUPERFAMILY SSF109604 307 384 1.81E-19 T 22-04-2016 HRM2_RS19995 c27cf4645e2a4e201d9832f1d4c21ef1 470 Gene3D G3DSA:1.10.3210.10 196 295 8.6E-9 T 22-04-2016 IPR006674 HD domain HRM2_RS19995 c27cf4645e2a4e201d9832f1d4c21ef1 470 Gene3D G3DSA:1.10.3210.10 330 348 8.6E-9 T 22-04-2016 IPR006674 HD domain HRM2_RS19995 c27cf4645e2a4e201d9832f1d4c21ef1 470 Pfam PF01966 HD domain 199 345 7.6E-7 T 22-04-2016 IPR006674 HD domain HRM2_RS11685 a1f0d4f499cd9dcae31930b745aebe26 315 SUPERFAMILY SSF103481 49 151 3.27E-14 T 22-04-2016 HRM2_RS11685 a1f0d4f499cd9dcae31930b745aebe26 315 Pfam PF00892 EamA-like transporter family 14 149 1.0E-24 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS11685 a1f0d4f499cd9dcae31930b745aebe26 315 Pfam PF00892 EamA-like transporter family 163 298 1.4E-20 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HRM2_RS11685 a1f0d4f499cd9dcae31930b745aebe26 315 PANTHER PTHR12715 15 301 4.8E-64 T 22-04-2016 HRM2_RS11685 a1f0d4f499cd9dcae31930b745aebe26 315 SUPERFAMILY SSF103481 199 299 6.02E-12 T 22-04-2016 HRM2_RS11685 a1f0d4f499cd9dcae31930b745aebe26 315 PANTHER PTHR12715:SF12 15 301 4.8E-64 T 22-04-2016 HRM2_RS25030 bbbbe66183fe2c8473c57381c1000571 321 PANTHER PTHR41247 185 306 2.8E-14 T 22-04-2016 HRM2_RS25030 bbbbe66183fe2c8473c57381c1000571 321 SMART SM00746 189 229 0.0077 T 22-04-2016 IPR011017 TRASH domain HRM2_RS25030 bbbbe66183fe2c8473c57381c1000571 321 SMART SM00746 49 88 67.0 T 22-04-2016 IPR011017 TRASH domain HRM2_RS25030 bbbbe66183fe2c8473c57381c1000571 321 Pfam PF05573 NosL 178 304 4.7E-21 T 22-04-2016 IPR008719 Nitrous oxide reductase accessory protein NosL HRM2_RS25030 bbbbe66183fe2c8473c57381c1000571 321 Pfam PF05573 NosL 47 153 4.6E-8 T 22-04-2016 IPR008719 Nitrous oxide reductase accessory protein NosL HRM2_RS25030 bbbbe66183fe2c8473c57381c1000571 321 SUPERFAMILY SSF160387 205 306 6.54E-24 T 22-04-2016 HRM2_RS25030 bbbbe66183fe2c8473c57381c1000571 321 SUPERFAMILY SSF160387 64 172 2.22E-20 T 22-04-2016 HRM2_RS23815 2fb1f0994324b01eca1ab22b02611b9b 272 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 16 224 4.1E-17 T 22-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 HRM2_RS23815 2fb1f0994324b01eca1ab22b02611b9b 272 SUPERFAMILY SSF56784 10 258 1.88E-25 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS23815 2fb1f0994324b01eca1ab22b02611b9b 272 Gene3D G3DSA:3.40.50.1000 137 159 7.2E-15 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS23815 2fb1f0994324b01eca1ab22b02611b9b 272 Gene3D G3DSA:3.40.50.1000 12 80 7.2E-15 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS23815 2fb1f0994324b01eca1ab22b02611b9b 272 Gene3D G3DSA:3.40.50.1000 196 257 7.2E-15 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS09110 7d83db26e9184ad4ee2e0374974e6ca6 434 PANTHER PTHR23417 37 120 1.1E-36 T 22-04-2016 HRM2_RS09110 7d83db26e9184ad4ee2e0374974e6ca6 434 PANTHER PTHR23417 139 149 1.1E-36 T 22-04-2016 HRM2_RS09110 7d83db26e9184ad4ee2e0374974e6ca6 434 PANTHER PTHR23417 197 431 1.1E-36 T 22-04-2016 HRM2_RS09110 7d83db26e9184ad4ee2e0374974e6ca6 434 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 42 216 5.5E-45 T 22-04-2016 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675|UniPathway: UPA00958 HRM2_RS09110 7d83db26e9184ad4ee2e0374974e6ca6 434 PANTHER PTHR23417:SF2 37 120 1.1E-36 T 22-04-2016 HRM2_RS09110 7d83db26e9184ad4ee2e0374974e6ca6 434 PANTHER PTHR23417:SF2 139 149 1.1E-36 T 22-04-2016 HRM2_RS09110 7d83db26e9184ad4ee2e0374974e6ca6 434 PANTHER PTHR23417:SF2 197 431 1.1E-36 T 22-04-2016 HRM2_RS09110 7d83db26e9184ad4ee2e0374974e6ca6 434 SUPERFAMILY SSF53756 54 414 3.14E-6 T 22-04-2016 HRM2_RS09795 577da1ecb51150a0693f171cda3ab230 134 SUPERFAMILY SSF81301 4 91 5.38E-14 T 22-04-2016 HRM2_RS09795 577da1ecb51150a0693f171cda3ab230 134 Pfam PF01909 Nucleotidyltransferase domain 12 68 3.8E-7 T 22-04-2016 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 HRM2_RS09795 577da1ecb51150a0693f171cda3ab230 134 Gene3D G3DSA:3.30.460.10 2 91 1.2E-16 T 22-04-2016 HRM2_RS04630 18bb18c47161b175e6a75dc851fb4096 451 SUPERFAMILY SSF53098 64 439 2.73E-40 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS04630 18bb18c47161b175e6a75dc851fb4096 451 Gene3D G3DSA:3.90.350.10 309 349 2.8E-5 T 22-04-2016 IPR014736 Transposase, Tn5-like, core HRM2_RS04630 18bb18c47161b175e6a75dc851fb4096 451 Pfam PF13546 DDE superfamily endonuclease 66 255 5.1E-13 T 22-04-2016 HRM2_RS04115 18bb18c47161b175e6a75dc851fb4096 451 SUPERFAMILY SSF53098 64 439 2.73E-40 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS04115 18bb18c47161b175e6a75dc851fb4096 451 Gene3D G3DSA:3.90.350.10 309 349 2.8E-5 T 22-04-2016 IPR014736 Transposase, Tn5-like, core HRM2_RS04115 18bb18c47161b175e6a75dc851fb4096 451 Pfam PF13546 DDE superfamily endonuclease 66 255 5.1E-13 T 22-04-2016 HRM2_RS03775 4db3526ab17917f5b1f23caaa7333d1c 615 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 4 34 1.4E-7 T 22-04-2016 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria HRM2_RS03775 4db3526ab17917f5b1f23caaa7333d1c 615 PANTHER PTHR10909 9 478 2.3E-130 T 22-04-2016 HRM2_RS03775 4db3526ab17917f5b1f23caaa7333d1c 615 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 284 452 4.2E-25 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS03775 4db3526ab17917f5b1f23caaa7333d1c 615 Gene3D G3DSA:2.40.110.10 161 265 1.2E-24 T 22-04-2016 HRM2_RS03775 4db3526ab17917f5b1f23caaa7333d1c 615 Gene3D G3DSA:1.10.540.10 39 158 2.1E-11 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS03775 4db3526ab17917f5b1f23caaa7333d1c 615 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 39 155 2.9E-7 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HRM2_RS03775 4db3526ab17917f5b1f23caaa7333d1c 615 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 469 610 2.1E-27 T 22-04-2016 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain HRM2_RS03775 4db3526ab17917f5b1f23caaa7333d1c 615 PANTHER PTHR10909:SF296 9 478 2.3E-130 T 22-04-2016 HRM2_RS03775 4db3526ab17917f5b1f23caaa7333d1c 615 SUPERFAMILY SSF47203 288 474 3.22E-46 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 HRM2_RS03775 4db3526ab17917f5b1f23caaa7333d1c 615 SUPERFAMILY SSF56645 39 269 4.32E-46 T 22-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 HRM2_RS03775 4db3526ab17917f5b1f23caaa7333d1c 615 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 161 269 1.9E-17 T 22-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 HRM2_RS03775 4db3526ab17917f5b1f23caaa7333d1c 615 Gene3D G3DSA:1.20.140.10 266 460 2.5E-50 T 22-04-2016 HRM2_RS22975 58273856eb8a34cf3058dbe740d84f84 152 Pfam PF04773 FecR protein 65 150 7.5E-10 T 22-04-2016 IPR006860 FecR protein HRM2_RS22090 180315bf64c6bdd80cb240c065bbef94 186 Pfam PF11823 Protein of unknown function (DUF3343) 26 92 1.3E-16 T 22-04-2016 IPR021778 Protein of unknown function DUF3343 HRM2_RS25505 699c2108bbeac8a7c312b7b413f41ea6 291 PANTHER PTHR12029 120 277 3.5E-43 T 22-04-2016 HRM2_RS25505 699c2108bbeac8a7c312b7b413f41ea6 291 SUPERFAMILY SSF75217 127 278 1.96E-42 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases HRM2_RS25505 699c2108bbeac8a7c312b7b413f41ea6 291 Pfam PF00588 SpoU rRNA Methylase family 134 274 3.9E-34 T 22-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 HRM2_RS25505 699c2108bbeac8a7c312b7b413f41ea6 291 Gene3D G3DSA:3.40.1280.10 127 278 6.0E-43 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HRM2_RS19295 f0885d15dce5896e796ed619e84b5230 304 SUPERFAMILY SSF109604 134 262 2.04E-17 T 22-04-2016 HRM2_RS19295 f0885d15dce5896e796ed619e84b5230 304 Pfam PF13487 HD domain 192 243 1.4E-10 T 22-04-2016 HRM2_RS19295 f0885d15dce5896e796ed619e84b5230 304 Gene3D G3DSA:1.10.3210.10 134 263 1.1E-15 T 22-04-2016 IPR006674 HD domain HRM2_RS23045 271d7420a9e432bd03aa2cbfc97bbaf9 327 PANTHER PTHR33376 26 321 2.9E-66 T 22-04-2016 HRM2_RS23045 271d7420a9e432bd03aa2cbfc97bbaf9 327 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 37 312 4.4E-37 T 22-04-2016 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 HRM2_RS23045 271d7420a9e432bd03aa2cbfc97bbaf9 327 PANTHER PTHR33376:SF1 26 321 2.9E-66 T 22-04-2016 HRM2_RS21070 6418ef1ef3299697d152d92d6293e603 215 Gene3D G3DSA:3.60.21.10 42 110 2.1E-15 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS21070 6418ef1ef3299697d152d92d6293e603 215 Gene3D G3DSA:3.60.21.10 143 208 2.1E-15 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS21070 6418ef1ef3299697d152d92d6293e603 215 Pfam PF00149 Calcineurin-like phosphoesterase 46 187 1.1E-8 T 22-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 HRM2_RS21070 6418ef1ef3299697d152d92d6293e603 215 SUPERFAMILY SSF56300 22 206 9.12E-22 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like HRM2_RS15240 a7f9dc914878db404701db6bfce21096 119 PANTHER PTHR24960 4 112 3.2E-23 T 22-04-2016 HRM2_RS15240 a7f9dc914878db404701db6bfce21096 119 Pfam PF02662 Methyl-viologen-reducing hydrogenase, delta subunit 2 104 3.6E-36 T 22-04-2016 IPR003813 Methyl-viologen-reducing hydrogenase, delta subunit GO:0015948|GO:0055114 HRM2_RS15240 a7f9dc914878db404701db6bfce21096 119 PANTHER PTHR24960:SF37 4 112 3.2E-23 T 22-04-2016 HRM2_RS19740 c481dfdb9cdcd53a6a90f3597e16d09a 270 PANTHER PTHR13939 5 256 3.4E-57 T 22-04-2016 HRM2_RS19740 c481dfdb9cdcd53a6a90f3597e16d09a 270 SMART SM00852 8 183 7.5E-30 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS19740 c481dfdb9cdcd53a6a90f3597e16d09a 270 Pfam PF00994 Probable molybdopterin binding domain 8 181 5.8E-34 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS19740 c481dfdb9cdcd53a6a90f3597e16d09a 270 Gene3D G3DSA:3.40.980.10 4 218 8.8E-36 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS19740 c481dfdb9cdcd53a6a90f3597e16d09a 270 SUPERFAMILY SSF53218 141 198 1.31E-35 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS19740 c481dfdb9cdcd53a6a90f3597e16d09a 270 SUPERFAMILY SSF53218 6 109 1.31E-35 T 22-04-2016 IPR001453 MoaB/Mog domain HRM2_RS18175 03e8d9a9bde5b8baa0b3f58013cf7a5a 245 Gene3D G3DSA:3.20.20.70 8 243 4.2E-66 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS18175 03e8d9a9bde5b8baa0b3f58013cf7a5a 245 SUPERFAMILY SSF51366 4 243 6.04E-58 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 HRM2_RS18175 03e8d9a9bde5b8baa0b3f58013cf7a5a 245 Pfam PF00977 Histidine biosynthesis protein 5 226 9.8E-61 T 22-04-2016 IPR006062 Histidine biosynthesis GO:0000105 HRM2_RS18175 03e8d9a9bde5b8baa0b3f58013cf7a5a 245 PANTHER PTHR21235:SF2 10 245 6.6E-67 T 22-04-2016 HRM2_RS18175 03e8d9a9bde5b8baa0b3f58013cf7a5a 245 PANTHER PTHR21235 10 245 6.6E-67 T 22-04-2016 HRM2_RS17290 e61f81b82934f94cd9fd394859c9686d 351 PANTHER PTHR33376 1 339 1.9E-58 T 22-04-2016 HRM2_RS17290 e61f81b82934f94cd9fd394859c9686d 351 SUPERFAMILY SSF53850 23 125 6.91E-8 T 22-04-2016 HRM2_RS17290 e61f81b82934f94cd9fd394859c9686d 351 SUPERFAMILY SSF53850 159 267 6.91E-8 T 22-04-2016 HRM2_RS17290 e61f81b82934f94cd9fd394859c9686d 351 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 39 318 4.0E-48 T 22-04-2016 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 HRM2_RS01000 bd06624f6e1ef15a3fcbe5847459ab78 351 PANTHER PTHR40690:SF1 1 348 5.9E-92 T 22-04-2016 HRM2_RS01000 bd06624f6e1ef15a3fcbe5847459ab78 351 Gene3D G3DSA:3.40.50.720 6 143 7.3E-47 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS01000 bd06624f6e1ef15a3fcbe5847459ab78 351 PANTHER PTHR40690 1 348 5.9E-92 T 22-04-2016 HRM2_RS01000 bd06624f6e1ef15a3fcbe5847459ab78 351 Gene3D G3DSA:3.40.50.300 149 349 3.3E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01000 bd06624f6e1ef15a3fcbe5847459ab78 351 PIRSF PIRSF026760 6 349 1.4E-101 T 22-04-2016 IPR011669 Protein of unknown function DUF1611 HRM2_RS01000 bd06624f6e1ef15a3fcbe5847459ab78 351 SUPERFAMILY SSF52540 7 348 2.44E-82 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS01000 bd06624f6e1ef15a3fcbe5847459ab78 351 Pfam PF07755 Protein of unknown function (DUF1611) 42 345 7.7E-82 T 22-04-2016 IPR011669 Protein of unknown function DUF1611 HRM2_RS17345 5ecabd4c244816996de1b4bfb3c7ec31 97 SUPERFAMILY SSF102829 5 94 1.05E-7 T 22-04-2016 IPR007838 Cell division protein ZapA-like HRM2_RS17345 5ecabd4c244816996de1b4bfb3c7ec31 97 Pfam PF05164 Cell division protein ZapA 5 92 4.0E-8 T 22-04-2016 IPR007838 Cell division protein ZapA-like HRM2_RS23870 8079e66fa4d3de2b6a7454eb7cc85151 78 Pfam PF13192 Thioredoxin domain 1 75 1.1E-28 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS23870 8079e66fa4d3de2b6a7454eb7cc85151 78 TIGRFAM TIGR00412 redox_disulf_2: redox-active disulfide protein 2 1 75 1.2E-27 T 22-04-2016 IPR005243 Redox-active disulphide protein 2 HRM2_RS23870 8079e66fa4d3de2b6a7454eb7cc85151 78 PANTHER PTHR36450:SF1 1 75 4.1E-30 T 22-04-2016 HRM2_RS23870 8079e66fa4d3de2b6a7454eb7cc85151 78 PIRSF PIRSF037031 1 77 7.5E-32 T 22-04-2016 IPR005243 Redox-active disulphide protein 2 HRM2_RS23870 8079e66fa4d3de2b6a7454eb7cc85151 78 PANTHER PTHR36450 1 75 4.1E-30 T 22-04-2016 HRM2_RS23870 8079e66fa4d3de2b6a7454eb7cc85151 78 Gene3D G3DSA:3.40.30.10 2 75 3.2E-30 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS23870 8079e66fa4d3de2b6a7454eb7cc85151 78 SUPERFAMILY SSF52833 2 75 1.78E-21 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS19685 a145579849e48e7b3fe030d945d9bcea 298 Gene3D G3DSA:3.30.300.30 189 287 1.6E-12 T 22-04-2016 HRM2_RS19685 a145579849e48e7b3fe030d945d9bcea 298 PANTHER PTHR24096 1 285 4.0E-39 T 22-04-2016 HRM2_RS19685 a145579849e48e7b3fe030d945d9bcea 298 Pfam PF00501 AMP-binding enzyme 3 177 1.9E-20 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HRM2_RS19685 a145579849e48e7b3fe030d945d9bcea 298 Gene3D G3DSA:2.30.38.10 104 179 5.5E-14 T 22-04-2016 HRM2_RS19685 a145579849e48e7b3fe030d945d9bcea 298 Gene3D G3DSA:3.40.50.980 2 90 2.5E-7 T 22-04-2016 HRM2_RS19685 a145579849e48e7b3fe030d945d9bcea 298 SUPERFAMILY SSF56801 2 286 4.84E-45 T 22-04-2016 HRM2_RS19685 a145579849e48e7b3fe030d945d9bcea 298 Pfam PF13193 AMP-binding enzyme C-terminal domain 199 276 9.8E-6 T 22-04-2016 IPR025110 AMP-binding enzyme C-terminal domain HRM2_RS19550 8ca720f6586ed70dd6e620d0cada71a7 455 Pfam PF12323 Helix-turn-helix domain 1 31 2.5E-6 T 22-04-2016 IPR021027 Transposase, putative, helix-turn-helix domain HRM2_RS19550 8ca720f6586ed70dd6e620d0cada71a7 455 Pfam PF07282 Putative transposase DNA-binding domain 334 403 6.7E-15 T 22-04-2016 IPR010095 Transposase IS605, OrfB, C-terminal HRM2_RS19550 8ca720f6586ed70dd6e620d0cada71a7 455 PANTHER PTHR30405:SF5 326 396 2.0E-37 T 22-04-2016 HRM2_RS19550 8ca720f6586ed70dd6e620d0cada71a7 455 PANTHER PTHR30405:SF5 1 178 2.0E-37 T 22-04-2016 HRM2_RS19550 8ca720f6586ed70dd6e620d0cada71a7 455 PANTHER PTHR30405:SF5 196 310 2.0E-37 T 22-04-2016 HRM2_RS19550 8ca720f6586ed70dd6e620d0cada71a7 455 PANTHER PTHR30405 326 396 2.0E-37 T 22-04-2016 HRM2_RS19550 8ca720f6586ed70dd6e620d0cada71a7 455 PANTHER PTHR30405 1 178 2.0E-37 T 22-04-2016 HRM2_RS19550 8ca720f6586ed70dd6e620d0cada71a7 455 PANTHER PTHR30405 196 310 2.0E-37 T 22-04-2016 HRM2_RS19550 8ca720f6586ed70dd6e620d0cada71a7 455 Pfam PF01385 Probable transposase 204 305 1.3E-12 T 22-04-2016 IPR001959 Probable transposase, IS891/IS1136/IS1341 HRM2_RS25150 9bea973ff3f0219a2dfd7cdc7a1c350b 1044 SUPERFAMILY SSF51126 82 516 3.01E-37 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor HRM2_RS25150 9bea973ff3f0219a2dfd7cdc7a1c350b 1044 Pfam PF13229 Right handed beta helix region 695 878 3.2E-11 T 22-04-2016 HRM2_RS25150 9bea973ff3f0219a2dfd7cdc7a1c350b 1044 Pfam PF13229 Right handed beta helix region 170 358 8.2E-8 T 22-04-2016 HRM2_RS25150 9bea973ff3f0219a2dfd7cdc7a1c350b 1044 SMART SM00710 292 315 530.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat HRM2_RS25150 9bea973ff3f0219a2dfd7cdc7a1c350b 1044 SMART SM00710 730 756 2700.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat HRM2_RS25150 9bea973ff3f0219a2dfd7cdc7a1c350b 1044 SMART SM00710 388 410 2600.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat HRM2_RS25150 9bea973ff3f0219a2dfd7cdc7a1c350b 1044 SMART SM00710 343 381 1400.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat HRM2_RS25150 9bea973ff3f0219a2dfd7cdc7a1c350b 1044 SMART SM00710 780 806 8500.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat HRM2_RS25150 9bea973ff3f0219a2dfd7cdc7a1c350b 1044 SMART SM00710 757 779 3.6 T 22-04-2016 IPR006626 Parallel beta-helix repeat HRM2_RS25150 9bea973ff3f0219a2dfd7cdc7a1c350b 1044 SMART SM00710 846 881 4800.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat HRM2_RS25150 9bea973ff3f0219a2dfd7cdc7a1c350b 1044 SMART SM00710 176 202 860.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat HRM2_RS25150 9bea973ff3f0219a2dfd7cdc7a1c350b 1044 SMART SM00710 211 232 970.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat HRM2_RS25150 9bea973ff3f0219a2dfd7cdc7a1c350b 1044 SMART SM00710 317 339 180.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat HRM2_RS25150 9bea973ff3f0219a2dfd7cdc7a1c350b 1044 SMART SM00710 234 256 210.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat HRM2_RS25150 9bea973ff3f0219a2dfd7cdc7a1c350b 1044 SMART SM00710 154 175 1700.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat HRM2_RS25150 9bea973ff3f0219a2dfd7cdc7a1c350b 1044 SMART SM00710 700 722 410.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat HRM2_RS25150 9bea973ff3f0219a2dfd7cdc7a1c350b 1044 Gene3D G3DSA:2.160.20.10 292 516 1.2E-33 T 22-04-2016 IPR012334 Pectin lyase fold HRM2_RS25150 9bea973ff3f0219a2dfd7cdc7a1c350b 1044 Gene3D G3DSA:2.160.20.10 82 259 1.2E-33 T 22-04-2016 IPR012334 Pectin lyase fold HRM2_RS25150 9bea973ff3f0219a2dfd7cdc7a1c350b 1044 Gene3D G3DSA:2.160.20.10 633 879 2.3E-22 T 22-04-2016 IPR012334 Pectin lyase fold HRM2_RS25150 9bea973ff3f0219a2dfd7cdc7a1c350b 1044 SUPERFAMILY SSF51126 632 880 4.43E-28 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor HRM2_RS17165 137fc5898dd537369cfd18641b3d2270 264 SUPERFAMILY SSF54637 123 263 2.86E-7 T 22-04-2016 IPR029069 HotDog domain HRM2_RS17165 137fc5898dd537369cfd18641b3d2270 264 Pfam PF13622 Thioesterase-like superfamily 27 260 6.9E-34 T 22-04-2016 HRM2_RS06950 2c5c068fbd99c014c0e1579401b0bf58 172 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 30 161 7.6E-25 T 22-04-2016 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component HRM2_RS06950 2c5c068fbd99c014c0e1579401b0bf58 172 PANTHER PTHR35011:SF4 6 161 6.1E-13 T 22-04-2016 HRM2_RS06950 2c5c068fbd99c014c0e1579401b0bf58 172 PANTHER PTHR35011 6 161 6.1E-13 T 22-04-2016 HRM2_RS12360 eacc26a1b1b95b9600ec509632ee6023 229 Gene3D G3DSA:3.40.50.300 21 168 1.3E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12360 eacc26a1b1b95b9600ec509632ee6023 229 SUPERFAMILY SSF52540 21 172 3.33E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12230 9e81dd75b18c0119eaae0bb3597b73b6 271 Pfam PF02535 ZIP Zinc transporter 114 266 4.0E-13 T 22-04-2016 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 HRM2_RS12230 9e81dd75b18c0119eaae0bb3597b73b6 271 PANTHER PTHR11040:SF33 1 271 3.4E-116 T 22-04-2016 HRM2_RS12230 9e81dd75b18c0119eaae0bb3597b73b6 271 PANTHER PTHR11040 1 271 3.4E-116 T 22-04-2016 HRM2_RS18820 432f5b768b0c4c226b7e9012c956e8c1 424 PANTHER PTHR30269 76 372 9.0E-72 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 HRM2_RS18820 432f5b768b0c4c226b7e9012c956e8c1 424 PANTHER PTHR30269:SF15 76 372 9.0E-72 T 22-04-2016 HRM2_RS18820 432f5b768b0c4c226b7e9012c956e8c1 424 Pfam PF01925 Sulfite exporter TauE/SafE 85 357 2.3E-34 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 HRM2_RS14470 663a90b745d4d98c7aab30a225a1053d 211 PANTHER PTHR30055 4 184 1.9E-25 T 22-04-2016 HRM2_RS14470 663a90b745d4d98c7aab30a225a1053d 211 Gene3D G3DSA:1.10.357.10 9 198 2.4E-33 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HRM2_RS14470 663a90b745d4d98c7aab30a225a1053d 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 3.1E-9 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS14470 663a90b745d4d98c7aab30a225a1053d 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 3.1E-9 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS14470 663a90b745d4d98c7aab30a225a1053d 211 SUPERFAMILY SSF46689 9 83 6.8E-17 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 HRM2_RS14470 663a90b745d4d98c7aab30a225a1053d 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 1.6E-14 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HRM2_RS24040 63f882b424ebecc0a1f225bd4c8fe118 134 PANTHER PTHR28630 1 132 1.9E-14 T 22-04-2016 IPR032801 Peroxiredoxin-like FAM213/AAED1 HRM2_RS24040 63f882b424ebecc0a1f225bd4c8fe118 134 Gene3D G3DSA:3.40.30.10 2 63 3.2E-7 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS24040 63f882b424ebecc0a1f225bd4c8fe118 134 Gene3D G3DSA:3.40.30.10 97 120 3.2E-7 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS24040 63f882b424ebecc0a1f225bd4c8fe118 134 Pfam PF13911 AhpC/TSA antioxidant enzyme 10 114 5.4E-11 T 22-04-2016 IPR032801 Peroxiredoxin-like FAM213/AAED1 HRM2_RS24040 63f882b424ebecc0a1f225bd4c8fe118 134 SUPERFAMILY SSF52833 2 134 1.73E-8 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS25070 7e42688d81f4d5514d235b066255c15f 263 Pfam PF01026 TatD related DNase 9 226 1.9E-12 T 22-04-2016 IPR001130 TatD family GO:0016788 HRM2_RS25070 7e42688d81f4d5514d235b066255c15f 263 Gene3D G3DSA:3.20.20.140 6 228 2.2E-20 T 22-04-2016 HRM2_RS25070 7e42688d81f4d5514d235b066255c15f 263 SUPERFAMILY SSF51556 8 259 3.1E-21 T 22-04-2016 IPR032466 Metal-dependent hydrolase HRM2_RS21905 4c9e87d27bd3b6cc63e54903b5f7705b 99 PANTHER PTHR11067:SF9 1 78 2.2E-17 T 22-04-2016 HRM2_RS21905 4c9e87d27bd3b6cc63e54903b5f7705b 99 Pfam PF01725 Ham1 family 3 86 1.7E-12 T 22-04-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 HRM2_RS21905 4c9e87d27bd3b6cc63e54903b5f7705b 99 PANTHER PTHR11067 1 78 2.2E-17 T 22-04-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 HRM2_RS21905 4c9e87d27bd3b6cc63e54903b5f7705b 99 Gene3D G3DSA:3.90.950.10 2 88 5.9E-19 T 22-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like HRM2_RS21905 4c9e87d27bd3b6cc63e54903b5f7705b 99 SUPERFAMILY SSF52972 2 91 2.41E-21 T 22-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like HRM2_RS12215 a1de1fe00530d4b9444f9b817ed24dc2 552 Gene3D G3DSA:3.30.70.1230 288 465 1.3E-17 T 22-04-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 HRM2_RS12215 a1de1fe00530d4b9444f9b817ed24dc2 552 SUPERFAMILY SSF55073 287 467 3.3E-22 T 22-04-2016 IPR029787 Nucleotide cyclase HRM2_RS12215 a1de1fe00530d4b9444f9b817ed24dc2 552 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 293 466 1.3E-11 T 22-04-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 HRM2_RS02100 95543a8c97ab254dc3f4b513c963a8f2 224 TIGRFAM TIGR02494 PFLE_PFLC: glycyl-radical enzyme activating protein 3 217 3.8E-65 T 22-04-2016 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 HRM2_RS02100 95543a8c97ab254dc3f4b513c963a8f2 224 PANTHER PTHR30352 22 224 7.6E-61 T 22-04-2016 HRM2_RS02100 95543a8c97ab254dc3f4b513c963a8f2 224 Pfam PF04055 Radical SAM superfamily 22 153 7.6E-22 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS02100 95543a8c97ab254dc3f4b513c963a8f2 224 Gene3D G3DSA:3.80.30.10 47 223 1.0E-58 T 22-04-2016 HRM2_RS02100 95543a8c97ab254dc3f4b513c963a8f2 224 Gene3D G3DSA:3.30.70.20 2 27 3.6E-7 T 22-04-2016 HRM2_RS02100 95543a8c97ab254dc3f4b513c963a8f2 224 SUPERFAMILY SSF54862 3 66 1.59E-6 T 22-04-2016 HRM2_RS02100 95543a8c97ab254dc3f4b513c963a8f2 224 PANTHER PTHR30352:SF4 22 224 7.6E-61 T 22-04-2016 HRM2_RS02100 95543a8c97ab254dc3f4b513c963a8f2 224 SUPERFAMILY SSF102114 50 191 1.69E-22 T 22-04-2016 HRM2_RS16605 05de0c2c4f002a0ab68c3c89f92f7dbe 288 SUPERFAMILY SSF53335 27 232 5.73E-23 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS16605 05de0c2c4f002a0ab68c3c89f92f7dbe 288 Pfam PF13649 Methyltransferase domain 75 167 7.1E-10 T 22-04-2016 HRM2_RS16605 05de0c2c4f002a0ab68c3c89f92f7dbe 288 PANTHER PTHR10108 23 152 1.1E-15 T 22-04-2016 HRM2_RS16605 05de0c2c4f002a0ab68c3c89f92f7dbe 288 Gene3D G3DSA:3.40.50.150 35 152 3.6E-18 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS23555 90c49b272d7522081a99c205a9916987 134 Gene3D G3DSA:3.30.1330.20 3 119 8.6E-40 T 22-04-2016 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain HRM2_RS23555 90c49b272d7522081a99c205a9916987 134 Pfam PF09585 Conserved hypothetical protein (Lin0512_fam) 5 116 7.4E-39 T 22-04-2016 IPR011719 Conserved hypothetical protein CHP02058 HRM2_RS23555 90c49b272d7522081a99c205a9916987 134 PANTHER PTHR34784 1 118 4.3E-28 T 22-04-2016 HRM2_RS23555 90c49b272d7522081a99c205a9916987 134 TIGRFAM TIGR02058 lin0512_fam: conserved hypothetical protein 4 117 1.9E-27 T 22-04-2016 IPR011719 Conserved hypothetical protein CHP02058 HRM2_RS15630 b456866528acbe50ca8f41cafe4e8d34 131 Gene3D G3DSA:1.10.3820.10 76 128 1.0E-5 T 22-04-2016 HRM2_RS15630 b456866528acbe50ca8f41cafe4e8d34 131 SUPERFAMILY SSF48695 83 128 4.01E-8 T 22-04-2016 IPR011031 Multihaem cytochrome HRM2_RS22400 cd49f29b705fd0dfe31cd34e591a796c 284 PANTHER PTHR30193:SF20 17 275 1.6E-40 T 22-04-2016 HRM2_RS22400 cd49f29b705fd0dfe31cd34e591a796c 284 SUPERFAMILY SSF161098 18 270 7.85E-40 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS22400 cd49f29b705fd0dfe31cd34e591a796c 284 PANTHER PTHR30193 17 275 1.6E-40 T 22-04-2016 HRM2_RS22400 cd49f29b705fd0dfe31cd34e591a796c 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 280 2.1E-11 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS22400 cd49f29b705fd0dfe31cd34e591a796c 284 Gene3D G3DSA:1.10.3720.10 16 282 4.4E-42 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS21210 53acf0300580c577074766be222dee08 409 PANTHER PTHR30548:SF4 1 408 2.9E-97 T 22-04-2016 HRM2_RS21210 53acf0300580c577074766be222dee08 409 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 46 404 1.6E-67 T 22-04-2016 IPR010327 FldB/FldC dehydratase alpha/beta subunit HRM2_RS21210 53acf0300580c577074766be222dee08 409 PANTHER PTHR30548 1 408 2.9E-97 T 22-04-2016 HRM2_RS22600 29b2f903367704c52d79d149a30cd5dd 434 PRINTS PR00173 Glutamate-aspartate symporter signature 297 323 2.6E-40 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HRM2_RS22600 29b2f903367704c52d79d149a30cd5dd 434 PRINTS PR00173 Glutamate-aspartate symporter signature 231 250 2.6E-40 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HRM2_RS22600 29b2f903367704c52d79d149a30cd5dd 434 PRINTS PR00173 Glutamate-aspartate symporter signature 359 379 2.6E-40 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HRM2_RS22600 29b2f903367704c52d79d149a30cd5dd 434 PRINTS PR00173 Glutamate-aspartate symporter signature 196 215 2.6E-40 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HRM2_RS22600 29b2f903367704c52d79d149a30cd5dd 434 PRINTS PR00173 Glutamate-aspartate symporter signature 332 351 2.6E-40 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HRM2_RS22600 29b2f903367704c52d79d149a30cd5dd 434 PRINTS PR00173 Glutamate-aspartate symporter signature 10 30 2.6E-40 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HRM2_RS22600 29b2f903367704c52d79d149a30cd5dd 434 PRINTS PR00173 Glutamate-aspartate symporter signature 76 101 2.6E-40 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HRM2_RS22600 29b2f903367704c52d79d149a30cd5dd 434 Pfam PF00375 Sodium:dicarboxylate symporter family 12 411 1.2E-120 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HRM2_RS22600 29b2f903367704c52d79d149a30cd5dd 434 PANTHER PTHR11958 1 423 4.1E-145 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HRM2_RS22600 29b2f903367704c52d79d149a30cd5dd 434 Gene3D G3DSA:1.10.3860.10 3 418 1.6E-133 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HRM2_RS22600 29b2f903367704c52d79d149a30cd5dd 434 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 39 54 - T 22-04-2016 IPR018107 Sodium:dicarboxylate symporter, conserved site Reactome: REACT_15518|Reactome: REACT_19419 HRM2_RS22600 29b2f903367704c52d79d149a30cd5dd 434 SUPERFAMILY SSF118215 12 413 1.02E-116 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HRM2_RS11275 b3348a66299fe338e6b7df7ddc9730be 140 PANTHER PTHR24960:SF37 8 124 4.7E-28 T 22-04-2016 HRM2_RS11275 b3348a66299fe338e6b7df7ddc9730be 140 PANTHER PTHR24960 8 124 4.7E-28 T 22-04-2016 HRM2_RS11275 b3348a66299fe338e6b7df7ddc9730be 140 Pfam PF02662 Methyl-viologen-reducing hydrogenase, delta subunit 8 130 2.4E-53 T 22-04-2016 IPR003813 Methyl-viologen-reducing hydrogenase, delta subunit GO:0015948|GO:0055114 HRM2_RS07180 9682a764a2f0f34398745b9e075a2ce7 165 Pfam PF03928 Haem-degrading 35 161 5.9E-31 T 22-04-2016 IPR005624 Haem-degrading HRM2_RS07180 9682a764a2f0f34398745b9e075a2ce7 165 SUPERFAMILY SSF143744 35 164 6.67E-37 T 22-04-2016 HRM2_RS07180 9682a764a2f0f34398745b9e075a2ce7 165 PANTHER PTHR34309:SF1 34 165 1.0E-31 T 22-04-2016 HRM2_RS07180 9682a764a2f0f34398745b9e075a2ce7 165 PANTHER PTHR34309 34 165 1.0E-31 T 22-04-2016 HRM2_RS25420 a852b07abafebfae83567b694e0ca54b 846 PANTHER PTHR23150 514 841 9.1E-46 T 22-04-2016 HRM2_RS25420 a852b07abafebfae83567b694e0ca54b 846 PANTHER PTHR23150 28 40 9.1E-46 T 22-04-2016 HRM2_RS25420 a852b07abafebfae83567b694e0ca54b 846 Pfam PF03781 Sulfatase-modifying factor enzyme 1 598 841 1.7E-41 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme HRM2_RS25420 a852b07abafebfae83567b694e0ca54b 846 SUPERFAMILY SSF56436 596 841 1.62E-52 T 22-04-2016 IPR016187 C-type lectin fold HRM2_RS25420 a852b07abafebfae83567b694e0ca54b 846 Gene3D G3DSA:3.90.1580.10 590 842 2.9E-51 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme HRM2_RS12460 68deaa3ee7cbb3f0a49a84b4c0b41161 304 PANTHER PTHR11795:SF371 1 295 5.4E-81 T 22-04-2016 HRM2_RS12460 68deaa3ee7cbb3f0a49a84b4c0b41161 304 PANTHER PTHR11795 1 295 5.4E-81 T 22-04-2016 HRM2_RS12460 68deaa3ee7cbb3f0a49a84b4c0b41161 304 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 286 5.6E-32 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 HRM2_RS07265 df3cc6a82a728307d72352f224343075 260 SUPERFAMILY SSF51658 2 255 1.57E-56 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain HRM2_RS07265 df3cc6a82a728307d72352f224343075 260 PANTHER PTHR12110:SF21 1 259 7.0E-50 T 22-04-2016 HRM2_RS07265 df3cc6a82a728307d72352f224343075 260 Gene3D G3DSA:3.20.20.150 2 255 3.1E-61 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain HRM2_RS07265 df3cc6a82a728307d72352f224343075 260 Pfam PF01261 Xylose isomerase-like TIM barrel 2 208 1.2E-37 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain HRM2_RS07265 df3cc6a82a728307d72352f224343075 260 PANTHER PTHR12110 1 259 7.0E-50 T 22-04-2016 HRM2_RS19960 edc3d7845927b2a563d0fc1f24f8b42b 273 PANTHER PTHR37296 1 272 7.5E-84 T 22-04-2016 HRM2_RS19960 edc3d7845927b2a563d0fc1f24f8b42b 273 Pfam PF13509 S1 domain 69 114 1.1E-8 T 22-04-2016 HRM2_RS19960 edc3d7845927b2a563d0fc1f24f8b42b 273 Pfam PF13509 S1 domain 4 62 3.5E-24 T 22-04-2016 HRM2_RS19960 edc3d7845927b2a563d0fc1f24f8b42b 273 PIRSF PIRSF012524 1 273 5.9E-73 T 22-04-2016 IPR014464 Conserved virulence factor B HRM2_RS21635 f18e7d40f1a8b2c5615899045ae0b073 185 PANTHER PTHR14119 11 185 2.4E-57 T 22-04-2016 HRM2_RS21635 f18e7d40f1a8b2c5615899045ae0b073 185 Gene3D G3DSA:3.40.50.850 8 185 6.9E-53 T 22-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 HRM2_RS21635 f18e7d40f1a8b2c5615899045ae0b073 185 SUPERFAMILY SSF52499 6 185 3.27E-42 T 22-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 HRM2_RS21635 f18e7d40f1a8b2c5615899045ae0b073 185 Pfam PF00857 Isochorismatase family 13 162 7.0E-31 T 22-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 HRM2_RS03290 533b9eafde0f0d9513c1c01addeddb21 250 Pfam PF16537 Type II secretion system protein B 191 244 2.4E-8 T 22-04-2016 IPR032389 Type II secretion system protein B HRM2_RS19575 f4607246a6fd433166fa3db3703b0615 250 Pfam PF01939 Protein of unknown function DUF91 122 222 2.1E-10 T 22-04-2016 IPR002793 Endonuclease NucS HRM2_RS14540 e998eb9255d4a2446859d659eec76b24 173 SUPERFAMILY SSF50630 11 144 4.73E-44 T 22-04-2016 IPR021109 Aspartic peptidase domain HRM2_RS14540 e998eb9255d4a2446859d659eec76b24 173 PANTHER PTHR38037 11 158 6.3E-49 T 22-04-2016 HRM2_RS14540 e998eb9255d4a2446859d659eec76b24 173 Pfam PF05618 Putative ATP-dependant zinc protease 11 145 3.9E-33 T 22-04-2016 HRM2_RS14540 e998eb9255d4a2446859d659eec76b24 173 Gene3D G3DSA:2.40.70.10 10 138 1.9E-42 T 22-04-2016 IPR021109 Aspartic peptidase domain HRM2_RS20825 6d8130b28522b057923c536d3376cd17 262 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 7 71 7.1E-16 T 22-04-2016 IPR002831 Transcription regulator TrmB, N-terminal HRM2_RS20825 6d8130b28522b057923c536d3376cd17 262 Pfam PF11495 Archaeal transcriptional regulator TrmB 104 203 1.1E-6 T 22-04-2016 IPR021586 Transcription regulator TrmB, C-terminal HRM2_RS20825 6d8130b28522b057923c536d3376cd17 262 Gene3D G3DSA:1.10.10.10 6 92 5.3E-8 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS20825 6d8130b28522b057923c536d3376cd17 262 SUPERFAMILY SSF46785 5 92 8.62E-6 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS20825 6d8130b28522b057923c536d3376cd17 262 PANTHER PTHR34293 1 256 1.1E-34 T 22-04-2016 HRM2_RS20825 6d8130b28522b057923c536d3376cd17 262 PANTHER PTHR34293:SF1 1 256 1.1E-34 T 22-04-2016 HRM2_RS00540 3b4b7682462a956f2a20667fa61f33a3 203 SMART SM00287 135 197 5.2E-8 T 22-04-2016 IPR003646 SH3-like domain, bacterial-type HRM2_RS00540 3b4b7682462a956f2a20667fa61f33a3 203 Pfam PF08239 Bacterial SH3 domain 145 192 1.7E-8 T 22-04-2016 IPR003646 SH3-like domain, bacterial-type HRM2_RS04770 076bb8b449356c82ab998f72a32d1489 126 PRINTS PR00340 P-II protein signature 63 86 6.0E-18 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HRM2_RS04770 076bb8b449356c82ab998f72a32d1489 126 PRINTS PR00340 P-II protein signature 23 41 6.0E-18 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HRM2_RS04770 076bb8b449356c82ab998f72a32d1489 126 PRINTS PR00340 P-II protein signature 2 17 6.0E-18 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HRM2_RS04770 076bb8b449356c82ab998f72a32d1489 126 PRINTS PR00340 P-II protein signature 94 114 6.0E-18 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HRM2_RS04770 076bb8b449356c82ab998f72a32d1489 126 PANTHER PTHR30115 1 123 2.5E-23 T 22-04-2016 HRM2_RS04770 076bb8b449356c82ab998f72a32d1489 126 PANTHER PTHR30115:SF14 1 123 2.5E-23 T 22-04-2016 HRM2_RS04770 076bb8b449356c82ab998f72a32d1489 126 Gene3D G3DSA:3.30.70.120 1 121 5.3E-31 T 22-04-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal HRM2_RS04770 076bb8b449356c82ab998f72a32d1489 126 Pfam PF00543 Nitrogen regulatory protein P-II 4 116 1.3E-24 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HRM2_RS04770 076bb8b449356c82ab998f72a32d1489 126 SUPERFAMILY SSF54913 1 122 5.72E-27 T 22-04-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta HRM2_RS04770 076bb8b449356c82ab998f72a32d1489 126 SMART SM00938 4 116 4.4E-31 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HRM2_RS00265 61ef73b83a1644241cff2b9378eaa496 138 SUPERFAMILY SSF118196 1 132 5.1E-39 T 22-04-2016 IPR023370 TsaA-like domain HRM2_RS00265 61ef73b83a1644241cff2b9378eaa496 138 Pfam PF01980 Uncharacterised protein family UPF0066 18 128 7.7E-32 T 22-04-2016 IPR023370 TsaA-like domain HRM2_RS00265 61ef73b83a1644241cff2b9378eaa496 138 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 1 129 1.0E-31 T 22-04-2016 IPR023370 TsaA-like domain HRM2_RS00265 61ef73b83a1644241cff2b9378eaa496 138 PANTHER PTHR12818 1 127 3.7E-37 T 22-04-2016 HRM2_RS00265 61ef73b83a1644241cff2b9378eaa496 138 Gene3D G3DSA:2.40.30.70 4 134 1.9E-40 T 22-04-2016 IPR023370 TsaA-like domain HRM2_RS05690 1e00530f148da371ab766c730d805945 283 SUPERFAMILY SSF53335 87 270 1.39E-23 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS05690 1e00530f148da371ab766c730d805945 283 Gene3D G3DSA:3.40.50.150 110 262 2.1E-21 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS05690 1e00530f148da371ab766c730d805945 283 PANTHER PTHR18895 112 264 5.1E-26 T 22-04-2016 HRM2_RS05690 1e00530f148da371ab766c730d805945 283 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 73 276 5.2E-37 T 22-04-2016 HRM2_RS05690 1e00530f148da371ab766c730d805945 283 PANTHER PTHR18895:SF3 112 264 5.1E-26 T 22-04-2016 HRM2_RS18245 dc45ace5ca9a3d6febeace92f9d3a440 101 Pfam PF10135 Rod binding protein 49 96 2.1E-15 T 22-04-2016 IPR019301 Flagellar protein FlgJ, N-terminal HRM2_RS20150 1f92090064bf44f4d9bb575da901825e 293 PANTHER PTHR30614 162 293 1.7E-71 T 22-04-2016 HRM2_RS20150 1f92090064bf44f4d9bb575da901825e 293 PANTHER PTHR30614:SF0 62 140 1.7E-71 T 22-04-2016 HRM2_RS20150 1f92090064bf44f4d9bb575da901825e 293 PANTHER PTHR30614:SF0 162 293 1.7E-71 T 22-04-2016 HRM2_RS20150 1f92090064bf44f4d9bb575da901825e 293 SUPERFAMILY SSF161098 158 275 5.36E-42 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS20150 1f92090064bf44f4d9bb575da901825e 293 SUPERFAMILY SSF161098 60 129 5.36E-42 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS20150 1f92090064bf44f4d9bb575da901825e 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 290 7.2E-20 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS20150 1f92090064bf44f4d9bb575da901825e 293 Gene3D G3DSA:1.10.3720.10 60 290 3.7E-44 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS20150 1f92090064bf44f4d9bb575da901825e 293 PANTHER PTHR30614 62 140 1.7E-71 T 22-04-2016 HRM2_RS20150 1f92090064bf44f4d9bb575da901825e 293 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 61 132 3.1E-15 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HRM2_RS21015 059ca3d1dad8e083a094692f00b534bf 231 Gene3D G3DSA:3.40.50.300 34 226 2.0E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS21015 059ca3d1dad8e083a094692f00b534bf 231 Pfam PF13189 Cytidylate kinase-like family 36 207 2.7E-42 T 22-04-2016 IPR026865 Cytidylate kinase-like family MetaCyc: PWY-7205 HRM2_RS20550 e5fbea65a65c73800ab138609dbefd6a 386 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 224 355 4.1E-12 T 22-04-2016 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HRM2_RS20550 e5fbea65a65c73800ab138609dbefd6a 386 Gene3D G3DSA:3.40.50.2000 202 356 2.6E-22 T 22-04-2016 HRM2_RS20550 e5fbea65a65c73800ab138609dbefd6a 386 SUPERFAMILY SSF53756 191 356 1.66E-16 T 22-04-2016 HRM2_RS20550 e5fbea65a65c73800ab138609dbefd6a 386 PANTHER PTHR21015:SF22 137 355 3.1E-15 T 22-04-2016 HRM2_RS20550 e5fbea65a65c73800ab138609dbefd6a 386 PANTHER PTHR21015 137 355 3.1E-15 T 22-04-2016 HRM2_RS04185 46dd6ec4254962f99afd58ee4ca27c25 241 PANTHER PTHR11558:SF4 62 207 3.2E-15 T 22-04-2016 HRM2_RS04185 46dd6ec4254962f99afd58ee4ca27c25 241 SUPERFAMILY SSF53335 60 224 2.09E-18 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS04185 46dd6ec4254962f99afd58ee4ca27c25 241 Gene3D G3DSA:3.40.50.150 67 216 9.1E-22 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS04185 46dd6ec4254962f99afd58ee4ca27c25 241 PANTHER PTHR11558 62 207 3.2E-15 T 22-04-2016 HRM2_RS10535 64fe1cd5f928c679de89d1f91295d284 286 PANTHER PTHR11795 1 285 1.8E-72 T 22-04-2016 HRM2_RS10535 64fe1cd5f928c679de89d1f91295d284 286 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 276 2.2E-39 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 HRM2_RS10535 64fe1cd5f928c679de89d1f91295d284 286 PANTHER PTHR11795:SF371 1 285 1.8E-72 T 22-04-2016 HRM2_RS11450 ddff035c05bb3dbc363c46479fd13108 614 Pfam PF00005 ABC transporter 300 430 1.8E-23 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS11450 ddff035c05bb3dbc363c46479fd13108 614 Pfam PF00005 ABC transporter 19 148 1.5E-23 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HRM2_RS11450 ddff035c05bb3dbc363c46479fd13108 614 PANTHER PTHR19211 514 552 6.0E-189 T 22-04-2016 HRM2_RS11450 ddff035c05bb3dbc363c46479fd13108 614 PANTHER PTHR19211 1 487 6.0E-189 T 22-04-2016 HRM2_RS11450 ddff035c05bb3dbc363c46479fd13108 614 Pfam PF12848 ABC transporter 189 264 2.8E-13 T 22-04-2016 IPR032781 ABC-transporter extension domain HRM2_RS11450 ddff035c05bb3dbc363c46479fd13108 614 SUPERFAMILY SSF52540 2 202 9.91E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11450 ddff035c05bb3dbc363c46479fd13108 614 SUPERFAMILY SSF52540 268 484 1.65E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11450 ddff035c05bb3dbc363c46479fd13108 614 Gene3D G3DSA:3.40.50.300 280 501 7.2E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11450 ddff035c05bb3dbc363c46479fd13108 614 Gene3D G3DSA:3.40.50.300 1 230 2.5E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS11450 ddff035c05bb3dbc363c46479fd13108 614 ProSitePatterns PS00211 ABC transporters family signature. 402 416 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HRM2_RS11450 ddff035c05bb3dbc363c46479fd13108 614 SMART SM00382 308 475 1.8E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS11450 ddff035c05bb3dbc363c46479fd13108 614 SMART SM00382 26 198 2.6E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS09165 2c577ecbf705737997e0d7acfe25a540 90 Pfam PF09928 Predicted small integral membrane protein (DUF2160) 3 90 2.0E-41 T 22-04-2016 IPR018678 Protein of unknown function DUF2160, transmembrane HRM2_RS08555 198dc3d83e0af7bf47fde8d3875bcef3 204 Pfam PF05908 Poly-gamma-glutamate hydrolase 5 192 7.7E-68 T 22-04-2016 IPR008585 Poly-gamma-glutamate hydrolase HRM2_RS13300 a8474248c6922284fe2c60792a0f2c41 160 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 2 134 8.5E-39 T 22-04-2016 IPR023370 TsaA-like domain HRM2_RS13300 a8474248c6922284fe2c60792a0f2c41 160 Gene3D G3DSA:2.40.30.70 2 143 3.9E-50 T 22-04-2016 IPR023370 TsaA-like domain HRM2_RS13300 a8474248c6922284fe2c60792a0f2c41 160 Pfam PF01980 Uncharacterised protein family UPF0066 19 131 5.9E-35 T 22-04-2016 IPR023370 TsaA-like domain HRM2_RS13300 a8474248c6922284fe2c60792a0f2c41 160 PANTHER PTHR12818 1 160 1.1E-52 T 22-04-2016 HRM2_RS13300 a8474248c6922284fe2c60792a0f2c41 160 SUPERFAMILY SSF118196 1 157 1.07E-50 T 22-04-2016 IPR023370 TsaA-like domain HRM2_RS10770 5ea139ffee506dd13f19d2fc1b2d814b 308 Pfam PF02374 Anion-transporting ATPase 6 252 5.1E-46 T 22-04-2016 IPR025723 Anion-transporting ATPase-like domain HRM2_RS10770 5ea139ffee506dd13f19d2fc1b2d814b 308 Gene3D G3DSA:3.40.50.300 197 255 2.2E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10770 5ea139ffee506dd13f19d2fc1b2d814b 308 Gene3D G3DSA:3.40.50.300 6 163 2.2E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10770 5ea139ffee506dd13f19d2fc1b2d814b 308 PANTHER PTHR10803:SF0 2 252 4.0E-47 T 22-04-2016 HRM2_RS10770 5ea139ffee506dd13f19d2fc1b2d814b 308 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 8 252 1.1E-44 T 22-04-2016 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 HRM2_RS10770 5ea139ffee506dd13f19d2fc1b2d814b 308 SUPERFAMILY SSF52540 6 254 2.09E-30 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS10770 5ea139ffee506dd13f19d2fc1b2d814b 308 PANTHER PTHR10803 2 252 4.0E-47 T 22-04-2016 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 HRM2_RS06960 886d9f514695dd2f76fcaa9477da6390 243 PANTHER PTHR30296:SF0 6 240 9.4E-102 T 22-04-2016 HRM2_RS06960 886d9f514695dd2f76fcaa9477da6390 243 PANTHER PTHR30296 6 240 9.4E-102 T 22-04-2016 HRM2_RS06960 886d9f514695dd2f76fcaa9477da6390 243 Pfam PF02754 Cysteine-rich domain 7 87 4.4E-16 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS06960 886d9f514695dd2f76fcaa9477da6390 243 Pfam PF02754 Cysteine-rich domain 136 221 1.0E-14 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS23465 4f4bf685e64252f79e5e601850123bf1 140 PANTHER PTHR11075 8 139 4.5E-39 T 22-04-2016 HRM2_RS23465 4f4bf685e64252f79e5e601850123bf1 140 Gene3D G3DSA:3.30.160.200 3 107 2.0E-35 T 22-04-2016 HRM2_RS23465 4f4bf685e64252f79e5e601850123bf1 140 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 21 37 - T 22-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 HRM2_RS23465 4f4bf685e64252f79e5e601850123bf1 140 Pfam PF00472 RF-1 domain 5 132 4.2E-27 T 22-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 HRM2_RS23465 4f4bf685e64252f79e5e601850123bf1 140 SUPERFAMILY SSF75620 7 108 1.29E-13 T 22-04-2016 HRM2_RS00285 e75d1fbee2a0a8061fae2a8368c19ddf 436 PANTHER PTHR11119 1 424 1.9E-16 T 22-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 HRM2_RS00285 e75d1fbee2a0a8061fae2a8368c19ddf 436 PANTHER PTHR11119:SF4 1 424 1.9E-16 T 22-04-2016 HRM2_RS00285 e75d1fbee2a0a8061fae2a8368c19ddf 436 Pfam PF00860 Permease family 18 391 6.1E-37 T 22-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 HRM2_RS18580 56d9aea35f4593a4155fc0259d553f15 126 Pfam PF04892 VanZ like family 36 115 7.1E-13 T 22-04-2016 IPR006976 VanZ-like HRM2_RS22840 d01a4932d63c0a942b4db52e18c67dd2 61 Gene3D G3DSA:3.40.250.10 2 61 8.6E-4 T 22-04-2016 IPR001763 Rhodanese-like domain HRM2_RS10740 458d5e01086454db4b670302422aefee 69 Pfam PF16256 Domain of unknown function (DUF4911) 8 64 2.4E-20 T 22-04-2016 IPR032587 Protein of unknown function DUF4911 HRM2_RS08985 fd7f427e43f1dbffd7fb90c0cd200f7f 280 Pfam PF03748 Flagellar basal body-associated protein FliL 151 249 9.1E-8 T 22-04-2016 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 HRM2_RS14555 6e53cf0a73251a43706eec78ff21aa2f 217 Pfam PF12118 SprA-related family 34 214 2.5E-35 T 22-04-2016 IPR021973 SprA-related family HRM2_RS09525 e54a7b3f86deb46fe0c3e1c605016f74 294 SUPERFAMILY SSF56672 44 229 3.78E-11 T 22-04-2016 HRM2_RS09525 e54a7b3f86deb46fe0c3e1c605016f74 294 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 45 234 5.8E-19 T 22-04-2016 IPR000477 Reverse transcriptase domain HRM2_RS09525 e54a7b3f86deb46fe0c3e1c605016f74 294 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 85 99 4.8E-18 T 22-04-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HRM2_RS09525 e54a7b3f86deb46fe0c3e1c605016f74 294 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 232 238 4.8E-18 T 22-04-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HRM2_RS09525 e54a7b3f86deb46fe0c3e1c605016f74 294 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 40 53 4.8E-18 T 22-04-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HRM2_RS09525 e54a7b3f86deb46fe0c3e1c605016f74 294 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 101 119 4.8E-18 T 22-04-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HRM2_RS09525 e54a7b3f86deb46fe0c3e1c605016f74 294 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 182 193 4.8E-18 T 22-04-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HRM2_RS09525 e54a7b3f86deb46fe0c3e1c605016f74 294 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 55 67 4.8E-18 T 22-04-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HRM2_RS09525 e54a7b3f86deb46fe0c3e1c605016f74 294 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 167 180 4.8E-18 T 22-04-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HRM2_RS09525 e54a7b3f86deb46fe0c3e1c605016f74 294 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 149 162 4.8E-18 T 22-04-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 HRM2_RS22360 14bcee776ed6a9416f1b345a78c04451 534 PANTHER PTHR32057 1 534 2.7E-217 T 22-04-2016 HRM2_RS22360 14bcee776ed6a9416f1b345a78c04451 534 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 33 500 5.1E-137 T 22-04-2016 IPR003846 Uncharacterised protein family UPF0061 HRM2_RS22360 14bcee776ed6a9416f1b345a78c04451 534 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 14 516 41.301 T 22-04-2016 IPR003846 Uncharacterised protein family UPF0061 HRM2_RS22210 7d1cde2b184d01114260652d95cdc68e 350 PANTHER PTHR10067:SF2 123 321 7.0E-23 T 22-04-2016 HRM2_RS22210 7d1cde2b184d01114260652d95cdc68e 350 Pfam PF02666 Phosphatidylserine decarboxylase 111 320 3.7E-37 T 22-04-2016 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|UniPathway: UPA00558 HRM2_RS22210 7d1cde2b184d01114260652d95cdc68e 350 PANTHER PTHR10067 123 321 7.0E-23 T 22-04-2016 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|UniPathway: UPA00558 HRM2_RS01440 90350b9881d52e9e9f5875b9ffc5209b 156 Pfam PF13490 Putative zinc-finger 12 39 1.4E-7 T 22-04-2016 IPR027383 Putative zinc-finger HRM2_RS02635 85f50bb19bfc987e3f3895b4c1d2d602 412 Pfam PF00860 Permease family 18 385 3.0E-89 T 22-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 HRM2_RS02635 85f50bb19bfc987e3f3895b4c1d2d602 412 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 16 409 1.4E-107 T 22-04-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 HRM2_RS02635 85f50bb19bfc987e3f3895b4c1d2d602 412 PANTHER PTHR11119:SF49 15 412 2.7E-156 T 22-04-2016 HRM2_RS02635 85f50bb19bfc987e3f3895b4c1d2d602 412 PANTHER PTHR11119 15 412 2.7E-156 T 22-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 HRM2_RS02635 85f50bb19bfc987e3f3895b4c1d2d602 412 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 333 353 - T 22-04-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 HRM2_RS05045 cda274e652b1634e87cc6efcb62f3e1f 304 PANTHER PTHR31752:SF13 107 304 1.9E-22 T 22-04-2016 HRM2_RS05045 cda274e652b1634e87cc6efcb62f3e1f 304 PANTHER PTHR31752 107 304 1.9E-22 T 22-04-2016 HRM2_RS05045 cda274e652b1634e87cc6efcb62f3e1f 304 Pfam PF03547 Membrane transport protein 160 300 1.2E-11 T 22-04-2016 IPR004776 Auxin efflux carrier GO:0016021|GO:0055085 HRM2_RS08845 bc53156ee8b55f4ed2c35ceea24b1054 160 Pfam PF01957 NfeD-like C-terminal, partner-binding 10 156 1.5E-10 T 22-04-2016 IPR002810 NfeD-like, C-terminal domain HRM2_RS22100 faff18e6dde2f405ee47d2192dc025a2 364 PANTHER PTHR30574:SF1 2 337 3.0E-33 T 22-04-2016 HRM2_RS22100 faff18e6dde2f405ee47d2192dc025a2 364 PANTHER PTHR30574 2 337 3.0E-33 T 22-04-2016 HRM2_RS22100 faff18e6dde2f405ee47d2192dc025a2 364 TIGRFAM TIGR04112 seleno_YedE: putative selenium metabolism protein, YedE family 12 355 3.9E-149 T 22-04-2016 IPR026366 Putative selenium metabolism protein, YedE family HRM2_RS22100 faff18e6dde2f405ee47d2192dc025a2 364 Pfam PF04143 Sulphur transport 219 329 1.8E-9 T 22-04-2016 IPR007272 Sulphur transport domain HRM2_RS24080 1b45636e33ff4da3a6bc8da1a27d2026 310 Pfam PF13536 Putative multidrug resistance efflux transporter 39 304 1.8E-95 T 22-04-2016 IPR032713 Putative multidrug resistance efflux transporter HRM2_RS23575 e8bd1509154f0f46d64681b51124488f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 1.0E-18 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS23575 e8bd1509154f0f46d64681b51124488f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.0E-18 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS23575 e8bd1509154f0f46d64681b51124488f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.0E-18 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS23575 e8bd1509154f0f46d64681b51124488f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.0E-18 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS23575 e8bd1509154f0f46d64681b51124488f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 1.0E-18 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS23575 e8bd1509154f0f46d64681b51124488f 261 PANTHER PTHR24322 15 189 4.7E-35 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HRM2_RS23575 e8bd1509154f0f46d64681b51124488f 261 Gene3D G3DSA:3.40.50.720 7 259 1.7E-53 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS23575 e8bd1509154f0f46d64681b51124488f 261 SUPERFAMILY SSF51735 5 259 1.26E-50 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS23575 e8bd1509154f0f46d64681b51124488f 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 258 6.7E-37 T 22-04-2016 HRM2_RS07195 811f5779b6525c2d3eaeaf656183cdee 69 Pfam PF00072 Response regulator receiver domain 1 60 2.6E-8 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HRM2_RS07195 811f5779b6525c2d3eaeaf656183cdee 69 SUPERFAMILY SSF52172 2 67 2.13E-13 T 22-04-2016 IPR011006 CheY-like superfamily HRM2_RS07195 811f5779b6525c2d3eaeaf656183cdee 69 Gene3D G3DSA:3.40.50.2300 1 67 9.3E-13 T 22-04-2016 HRM2_RS08335 0b15f48b67748acb126a2941b870b27c 102 Pfam PF08899 Domain of unknown function (DUF1844) 25 97 3.8E-30 T 22-04-2016 IPR014995 Protein of unknown function DUF1844 HRM2_RS14260 26711f14842aab07e929b863512840c4 270 Pfam PF12654 Domain of unknown function (DUF3786) 84 255 4.3E-46 T 22-04-2016 IPR024264 Domain of unknown function DUF3786 HRM2_RS14260 26711f14842aab07e929b863512840c4 270 Pfam PF04060 Putative Fe-S cluster 14 46 8.8E-10 T 22-04-2016 IPR007202 4Fe-4S domain GO:0051536 HRM2_RS19855 e9d5c4e18fcc4de5cff308e36652e692 185 SUPERFAMILY SSF54631 3 77 7.96E-15 T 22-04-2016 HRM2_RS19855 e9d5c4e18fcc4de5cff308e36652e692 185 SUPERFAMILY SSF54631 117 177 7.96E-15 T 22-04-2016 HRM2_RS19855 e9d5c4e18fcc4de5cff308e36652e692 185 Gene3D G3DSA:3.10.580.10 5 75 1.2E-11 T 22-04-2016 HRM2_RS19855 e9d5c4e18fcc4de5cff308e36652e692 185 Gene3D G3DSA:3.10.580.10 116 177 1.2E-11 T 22-04-2016 HRM2_RS19855 e9d5c4e18fcc4de5cff308e36652e692 185 Pfam PF00571 CBS domain 5 70 6.3E-4 T 22-04-2016 IPR000644 CBS domain HRM2_RS19855 e9d5c4e18fcc4de5cff308e36652e692 185 Pfam PF00571 CBS domain 122 176 7.6E-5 T 22-04-2016 IPR000644 CBS domain HRM2_RS21625 5420773d51c33b6fbf2c787774f2377c 548 SUPERFAMILY SSF58104 225 547 2.62E-64 T 22-04-2016 HRM2_RS21625 5420773d51c33b6fbf2c787774f2377c 548 SMART SM00283 286 547 1.8E-59 T 22-04-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HRM2_RS21625 5420773d51c33b6fbf2c787774f2377c 548 Pfam PF00672 HAMP domain 191 253 7.2E-11 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS21625 5420773d51c33b6fbf2c787774f2377c 548 SMART SM00304 205 257 6.9E-9 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HRM2_RS21625 5420773d51c33b6fbf2c787774f2377c 548 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 454 483 1.6E-23 T 22-04-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HRM2_RS21625 5420773d51c33b6fbf2c787774f2377c 548 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 406 435 1.6E-23 T 22-04-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HRM2_RS21625 5420773d51c33b6fbf2c787774f2377c 548 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 300 329 1.6E-23 T 22-04-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HRM2_RS21625 5420773d51c33b6fbf2c787774f2377c 548 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 377 404 1.6E-23 T 22-04-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HRM2_RS21625 5420773d51c33b6fbf2c787774f2377c 548 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 17 42 1.6E-23 T 22-04-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HRM2_RS21625 5420773d51c33b6fbf2c787774f2377c 548 Gene3D G3DSA:1.10.287.950 294 503 4.3E-47 T 22-04-2016 HRM2_RS21625 5420773d51c33b6fbf2c787774f2377c 548 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 349 546 4.2E-35 T 22-04-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HRM2_RS21625 5420773d51c33b6fbf2c787774f2377c 548 PANTHER PTHR32089 149 548 1.3E-99 T 22-04-2016 HRM2_RS00595 e54e1e869360f6751992abea4ac9eac9 99 SUPERFAMILY SSF51717 3 92 1.44E-22 T 22-04-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 HRM2_RS00595 e54e1e869360f6751992abea4ac9eac9 99 Gene3D G3DSA:3.20.20.20 3 93 7.9E-24 T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 HRM2_RS00595 e54e1e869360f6751992abea4ac9eac9 99 Pfam PF00809 Pterin binding enzyme 6 88 4.9E-9 T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 HRM2_RS12005 5aad57d2fb84a1291ccb3a6a5a78055f 222 SUPERFAMILY SSF51735 3 85 2.55E-5 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS12005 5aad57d2fb84a1291ccb3a6a5a78055f 222 Gene3D G3DSA:3.40.50.720 4 55 7.0E-7 T 22-04-2016 IPR016040 NAD(P)-binding domain HRM2_RS12005 5aad57d2fb84a1291ccb3a6a5a78055f 222 Pfam PF02254 TrkA-N domain 5 55 1.4E-5 T 22-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 HRM2_RS16535 14dab180cbb7f40128f6f44e0ebd3e89 369 PANTHER PTHR31332 12 319 2.6E-44 T 22-04-2016 HRM2_RS16535 14dab180cbb7f40128f6f44e0ebd3e89 369 SUPERFAMILY SSF54862 5 66 2.03E-8 T 22-04-2016 HRM2_RS16535 14dab180cbb7f40128f6f44e0ebd3e89 369 Gene3D G3DSA:3.30.70.20 10 60 1.9E-6 T 22-04-2016 HRM2_RS16535 14dab180cbb7f40128f6f44e0ebd3e89 369 Pfam PF00037 4Fe-4S binding domain 13 31 1.0E-5 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS16535 14dab180cbb7f40128f6f44e0ebd3e89 369 Pfam PF04432 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus 169 322 1.4E-31 T 22-04-2016 IPR007525 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal HRM2_RS16535 14dab180cbb7f40128f6f44e0ebd3e89 369 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 19 30 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS16535 14dab180cbb7f40128f6f44e0ebd3e89 369 Pfam PF04422 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term 97 160 6.9E-13 T 22-04-2016 IPR007516 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal HRM2_RS06780 3bbf0506e7c2c3fb9a6f82aaa0d72b5f 236 SMART SM00287 34 97 2.2E-6 T 22-04-2016 IPR003646 SH3-like domain, bacterial-type HRM2_RS06780 3bbf0506e7c2c3fb9a6f82aaa0d72b5f 236 TIGRFAM TIGR04211 SH3_and_anchor: SH3 domain protein 38 230 2.0E-38 T 22-04-2016 IPR016476 SH3 domain protein HRM2_RS06780 3bbf0506e7c2c3fb9a6f82aaa0d72b5f 236 Pfam PF08239 Bacterial SH3 domain 46 94 1.4E-12 T 22-04-2016 IPR003646 SH3-like domain, bacterial-type HRM2_RS21100 1d5ab8be50c669def53c914cd5e1cdb7 143 SUPERFAMILY SSF52833 26 138 3.36E-21 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS21100 1d5ab8be50c669def53c914cd5e1cdb7 143 Pfam PF01323 DSBA-like thioredoxin domain 4 134 9.1E-15 T 22-04-2016 IPR001853 DSBA-like thioredoxin domain GO:0015035 HRM2_RS21100 1d5ab8be50c669def53c914cd5e1cdb7 143 Gene3D G3DSA:3.40.30.10 7 136 3.5E-18 T 22-04-2016 IPR012336 Thioredoxin-like fold HRM2_RS07880 31e8a10738bba1cd4eb34b8d8eab64fc 475 SUPERFAMILY SSF56954 4 33 2.88E-96 T 22-04-2016 HRM2_RS07880 31e8a10738bba1cd4eb34b8d8eab64fc 475 SUPERFAMILY SSF56954 62 473 2.88E-96 T 22-04-2016 HRM2_RS07880 31e8a10738bba1cd4eb34b8d8eab64fc 475 PANTHER PTHR30203 4 473 2.0E-130 T 22-04-2016 HRM2_RS07880 31e8a10738bba1cd4eb34b8d8eab64fc 475 Pfam PF02321 Outer membrane efflux protein 73 260 1.4E-20 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS07880 31e8a10738bba1cd4eb34b8d8eab64fc 475 Pfam PF02321 Outer membrane efflux protein 289 471 2.4E-26 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HRM2_RS07880 31e8a10738bba1cd4eb34b8d8eab64fc 475 Gene3D G3DSA:1.20.1600.10 61 473 1.9E-102 T 22-04-2016 HRM2_RS07880 31e8a10738bba1cd4eb34b8d8eab64fc 475 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 14 473 1.3E-107 T 22-04-2016 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 HRM2_RS07880 31e8a10738bba1cd4eb34b8d8eab64fc 475 PANTHER PTHR30203:SF15 4 473 2.0E-130 T 22-04-2016 HRM2_RS14935 d81883c147c52acdc5bc88461e6cff47 409 PANTHER PTHR30012 2 409 7.6E-135 T 22-04-2016 HRM2_RS14935 d81883c147c52acdc5bc88461e6cff47 409 PRINTS PR00812 Bacterial general secretion pathway protein F signature 71 83 4.8E-16 T 22-04-2016 IPR003004 GspF/PilC family HRM2_RS14935 d81883c147c52acdc5bc88461e6cff47 409 PRINTS PR00812 Bacterial general secretion pathway protein F signature 170 198 4.8E-16 T 22-04-2016 IPR003004 GspF/PilC family HRM2_RS14935 d81883c147c52acdc5bc88461e6cff47 409 PRINTS PR00812 Bacterial general secretion pathway protein F signature 389 408 4.8E-16 T 22-04-2016 IPR003004 GspF/PilC family HRM2_RS14935 d81883c147c52acdc5bc88461e6cff47 409 PRINTS PR00812 Bacterial general secretion pathway protein F signature 373 387 4.8E-16 T 22-04-2016 IPR003004 GspF/PilC family HRM2_RS14935 d81883c147c52acdc5bc88461e6cff47 409 PANTHER PTHR30012:SF0 2 409 7.6E-135 T 22-04-2016 HRM2_RS14935 d81883c147c52acdc5bc88461e6cff47 409 Pfam PF00482 Type II secretion system (T2SS), protein F 75 198 2.7E-27 T 22-04-2016 IPR018076 Type II secretion system F domain HRM2_RS14935 d81883c147c52acdc5bc88461e6cff47 409 Pfam PF00482 Type II secretion system (T2SS), protein F 279 399 5.1E-29 T 22-04-2016 IPR018076 Type II secretion system F domain HRM2_RS25570 6ffa00e5d83ee45473cfaa31e2364a5b 123 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 66 120 6.5E-7 T 22-04-2016 IPR008792 Coenzyme PQQ synthesis D UniPathway: UPA00539 HRM2_RS21530 3dcc992e220e0b69ab4d8b85642bf442 240 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 19 125 1.7E-16 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HRM2_RS21530 3dcc992e220e0b69ab4d8b85642bf442 240 SUPERFAMILY SSF161098 19 222 2.09E-37 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS21530 3dcc992e220e0b69ab4d8b85642bf442 240 Gene3D G3DSA:1.10.3720.10 17 229 2.8E-40 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS21530 3dcc992e220e0b69ab4d8b85642bf442 240 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 39 215 1.5E-16 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS21530 3dcc992e220e0b69ab4d8b85642bf442 240 PANTHER PTHR30614 1 236 2.2E-58 T 22-04-2016 HRM2_RS13725 18568871ad0d677601c346c097c9507b 276 Pfam PF12679 ABC-2 family transporter protein 74 261 9.3E-9 T 22-04-2016 IPR032688 ABC-2 family transporter protein GO:0006810 HRM2_RS15235 7dce1e9a98fc3ecd8820519faa7470c4 222 PANTHER PTHR38755 1 218 4.0E-18 T 22-04-2016 HRM2_RS15235 7dce1e9a98fc3ecd8820519faa7470c4 222 Pfam PF12225 Methylene-tetrahydrofolate reductase C terminal 112 205 2.6E-37 T 22-04-2016 IPR022026 Methylene-tetrahydrofolate reductase C-terminal HRM2_RS15235 7dce1e9a98fc3ecd8820519faa7470c4 222 PANTHER PTHR38755:SF1 1 218 4.0E-18 T 22-04-2016 HRM2_RS04475 46ed8977701120912625041a439d3076 476 Pfam PF06253 Trimethylamine methyltransferase (MTTB) 7 474 1.3E-123 T 22-04-2016 IPR010426 Trimethylamine methyltransferase GO:0008168|GO:0015948 KEGG: 00680+2.1.1.250|MetaCyc: PWY-5250|UniPathway: UPA00645 HRM2_RS04475 46ed8977701120912625041a439d3076 476 PIRSF PIRSF037567 2 475 9.8E-127 T 22-04-2016 IPR010426 Trimethylamine methyltransferase GO:0008168|GO:0015948 KEGG: 00680+2.1.1.250|MetaCyc: PWY-5250|UniPathway: UPA00645 HRM2_RS02350 e3c911533bf79c1a25d8b04f83ac8936 192 PANTHER PTHR38659 6 192 4.0E-89 T 22-04-2016 HRM2_RS02350 e3c911533bf79c1a25d8b04f83ac8936 192 PANTHER PTHR38659:SF2 6 192 4.0E-89 T 22-04-2016 HRM2_RS02350 e3c911533bf79c1a25d8b04f83ac8936 192 SUPERFAMILY SSF109604 17 163 4.89E-12 T 22-04-2016 HRM2_RS02350 e3c911533bf79c1a25d8b04f83ac8936 192 Gene3D G3DSA:1.10.3210.10 6 157 3.0E-30 T 22-04-2016 IPR006674 HD domain HRM2_RS19460 824b5bd3f1a6ff05b17544cfac860137 121 Gene3D G3DSA:2.40.10.220 33 101 3.4E-4 T 22-04-2016 HRM2_RS19460 824b5bd3f1a6ff05b17544cfac860137 121 SUPERFAMILY SSF141371 33 101 4.71E-7 T 22-04-2016 HRM2_RS19460 824b5bd3f1a6ff05b17544cfac860137 121 Pfam PF07238 PilZ domain 33 100 2.5E-6 T 22-04-2016 IPR009875 PilZ domain GO:0035438 HRM2_RS04085 a9622af960ca52d41bd6e5b9a945eed4 727 Gene3D G3DSA:3.40.50.410 246 380 4.8E-6 T 22-04-2016 IPR002035 von Willebrand factor, type A HRM2_RS04085 a9622af960ca52d41bd6e5b9a945eed4 727 SUPERFAMILY SSF53300 247 440 3.89E-10 T 22-04-2016 IPR002035 von Willebrand factor, type A HRM2_RS01070 5fed932b9493579f72a4b72509c46a2e 147 Gene3D G3DSA:3.10.129.10 2 147 2.3E-39 T 22-04-2016 IPR029069 HotDog domain HRM2_RS01070 5fed932b9493579f72a4b72509c46a2e 147 SUPERFAMILY SSF54637 7 144 8.25E-23 T 22-04-2016 IPR029069 HotDog domain HRM2_RS01070 5fed932b9493579f72a4b72509c46a2e 147 Pfam PF14539 Domain of unknown function (DUF4442) 7 143 3.0E-23 T 22-04-2016 IPR027961 Protein of unknown function DUF4442 HRM2_RS13150 ec915592dbf2c3abe6834a3ebc4d2ac9 249 PANTHER PTHR30151 8 248 3.0E-31 T 22-04-2016 HRM2_RS13150 ec915592dbf2c3abe6834a3ebc4d2ac9 249 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 236 3.6E-11 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS13150 ec915592dbf2c3abe6834a3ebc4d2ac9 249 Gene3D G3DSA:1.10.3720.10 48 237 1.0E-14 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS13150 ec915592dbf2c3abe6834a3ebc4d2ac9 249 SUPERFAMILY SSF161098 49 229 9.29E-18 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS12135 ea405249210beeb35738d3b029de0afa 314 Gene3D G3DSA:1.25.40.10 58 294 2.3E-6 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS12135 ea405249210beeb35738d3b029de0afa 314 SUPERFAMILY SSF48452 244 292 4.93E-8 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS12135 ea405249210beeb35738d3b029de0afa 314 SUPERFAMILY SSF48452 50 157 4.93E-8 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS04190 4fb115921945ecb35c163658656eb068 396 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 5 354 1.7E-69 T 22-04-2016 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 HRM2_RS04190 4fb115921945ecb35c163658656eb068 396 Pfam PF07690 Major Facilitator Superfamily 13 348 1.4E-46 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS04190 4fb115921945ecb35c163658656eb068 396 PANTHER PTHR23502:SF19 1 381 1.4E-78 T 22-04-2016 HRM2_RS04190 4fb115921945ecb35c163658656eb068 396 PANTHER PTHR23502 1 381 1.4E-78 T 22-04-2016 HRM2_RS04190 4fb115921945ecb35c163658656eb068 396 Gene3D G3DSA:1.20.1250.20 200 353 2.2E-11 T 22-04-2016 HRM2_RS04190 4fb115921945ecb35c163658656eb068 396 SUPERFAMILY SSF103473 5 381 6.41E-63 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS04190 4fb115921945ecb35c163658656eb068 396 Gene3D G3DSA:1.20.1250.20 4 185 8.0E-33 T 22-04-2016 HRM2_RS11020 d3e0bd3d8c9c1bd27d6d8a7ec2e90640 243 SUPERFAMILY SSF52266 43 241 1.25E-25 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain HRM2_RS11020 d3e0bd3d8c9c1bd27d6d8a7ec2e90640 243 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 47 230 1.1E-17 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain HRM2_RS11020 d3e0bd3d8c9c1bd27d6d8a7ec2e90640 243 Gene3D G3DSA:3.40.50.1110 43 240 1.2E-26 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain HRM2_RS09870 7bf9ea3e722db87471622580c77dbf04 538 Gene3D G3DSA:3.20.20.370 211 429 1.8E-22 T 22-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 HRM2_RS09870 7bf9ea3e722db87471622580c77dbf04 538 SUPERFAMILY SSF88713 207 430 4.7E-23 T 22-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 HRM2_RS06505 e41edf8f1a0b50cd0e1b7418b4c2bf2b 1026 SUPERFAMILY SSF160113 756 815 3.01E-6 T 22-04-2016 IPR010879 Domain of unknown function DUF1508 HRM2_RS06505 e41edf8f1a0b50cd0e1b7418b4c2bf2b 1026 Gene3D G3DSA:3.30.160.160 757 804 2.7E-4 T 22-04-2016 IPR010879 Domain of unknown function DUF1508 HRM2_RS09370 46e76c8a4356cb26d67e3d7339236ea8 93 Pfam PF13616 PPIC-type PPIASE domain 5 91 7.5E-23 T 22-04-2016 HRM2_RS09370 46e76c8a4356cb26d67e3d7339236ea8 93 Gene3D G3DSA:3.10.50.40 3 92 5.1E-34 T 22-04-2016 HRM2_RS09370 46e76c8a4356cb26d67e3d7339236ea8 93 PANTHER PTHR10657 6 93 2.0E-38 T 22-04-2016 HRM2_RS09370 46e76c8a4356cb26d67e3d7339236ea8 93 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 30 50 - T 22-04-2016 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site HRM2_RS09370 46e76c8a4356cb26d67e3d7339236ea8 93 SUPERFAMILY SSF54534 3 89 2.81E-29 T 22-04-2016 HRM2_RS15140 f4a3b6ddd88b97cfb467384ea471da6f 445 Gene3D G3DSA:3.80.30.20 208 378 6.2E-12 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe HRM2_RS15140 f4a3b6ddd88b97cfb467384ea471da6f 445 SUPERFAMILY SSF102114 211 365 4.45E-13 T 22-04-2016 HRM2_RS15620 5f858c813c303f21dae2b9df5984327e 335 Gene3D G3DSA:1.20.950.20 28 61 3.4E-49 T 22-04-2016 HRM2_RS15620 5f858c813c303f21dae2b9df5984327e 335 Gene3D G3DSA:1.20.950.20 102 290 3.4E-49 T 22-04-2016 HRM2_RS15620 5f858c813c303f21dae2b9df5984327e 335 SUPERFAMILY SSF103501 106 302 3.27E-51 T 22-04-2016 IPR023234 NarG-like domain HRM2_RS15620 5f858c813c303f21dae2b9df5984327e 335 SUPERFAMILY SSF103501 28 51 3.27E-51 T 22-04-2016 IPR023234 NarG-like domain HRM2_RS15620 5f858c813c303f21dae2b9df5984327e 335 Pfam PF02665 Nitrate reductase gamma subunit 98 282 9.3E-15 T 22-04-2016 IPR023234 NarG-like domain HRM2_RS15755 6b4266f4d2f13eb55c47c8b2e35ace02 307 Pfam PF01553 Acyltransferase 77 228 5.0E-14 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 HRM2_RS15755 6b4266f4d2f13eb55c47c8b2e35ace02 307 SMART SM00563 89 231 4.2E-21 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 HRM2_RS15755 6b4266f4d2f13eb55c47c8b2e35ace02 307 PANTHER PTHR10983:SF15 1 294 1.1E-120 T 22-04-2016 HRM2_RS15755 6b4266f4d2f13eb55c47c8b2e35ace02 307 SUPERFAMILY SSF69593 16 298 3.4E-30 T 22-04-2016 HRM2_RS15755 6b4266f4d2f13eb55c47c8b2e35ace02 307 PANTHER PTHR10983 1 294 1.1E-120 T 22-04-2016 HRM2_RS22855 7edf77f1c90a2fe94e475f551f5a3748 349 Pfam PF02653 Branched-chain amino acid transport system / permease component 59 320 4.7E-36 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 HRM2_RS22855 7edf77f1c90a2fe94e475f551f5a3748 349 PANTHER PTHR32196 1 348 7.0E-66 T 22-04-2016 HRM2_RS22855 7edf77f1c90a2fe94e475f551f5a3748 349 PANTHER PTHR32196:SF30 1 348 7.0E-66 T 22-04-2016 HRM2_RS03085 508d2e4a89e02ac8443ab93355d888f2 306 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 279 1.7E-33 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 HRM2_RS03085 508d2e4a89e02ac8443ab93355d888f2 306 PANTHER PTHR32196:SF33 15 304 6.1E-108 T 22-04-2016 HRM2_RS03085 508d2e4a89e02ac8443ab93355d888f2 306 PANTHER PTHR32196 15 304 6.1E-108 T 22-04-2016 HRM2_RS09935 f671d5a032024f417af2fe5759668c96 309 TIGRFAM TIGR03790 TIGR03790: TIGR03790 family protein 152 293 3.3E-54 T 22-04-2016 IPR022265 Conserved hypothetical protein CHP03790 HRM2_RS09935 f671d5a032024f417af2fe5759668c96 309 TIGRFAM TIGR03790 TIGR03790: TIGR03790 family protein 12 144 1.1E-26 T 22-04-2016 IPR022265 Conserved hypothetical protein CHP03790 HRM2_RS05750 0aece03d5bcc7993ac79a7b877c557f5 331 Pfam PF11383 Protein of unknown function (DUF3187) 7 331 1.5E-123 T 22-04-2016 IPR021523 Protein of unknown function DUF3187 HRM2_RS14770 68e34658615fe1ace0d04c5dec6b76d6 135 Pfam PF04138 GtrA-like protein 16 126 2.7E-12 T 22-04-2016 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 HRM2_RS18725 b8a1d350829cf39a1757d7dea7c2a561 508 SUPERFAMILY SSF55874 45 145 1.1E-8 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS18725 b8a1d350829cf39a1757d7dea7c2a561 508 Gene3D G3DSA:3.30.565.10 41 146 3.3E-8 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS18725 b8a1d350829cf39a1757d7dea7c2a561 508 PANTHER PTHR35526 17 158 8.0E-13 T 22-04-2016 HRM2_RS18725 b8a1d350829cf39a1757d7dea7c2a561 508 Pfam PF00583 Acetyltransferase (GNAT) family 230 306 6.5E-6 T 22-04-2016 IPR000182 GNAT domain GO:0008080 HRM2_RS18725 b8a1d350829cf39a1757d7dea7c2a561 508 Pfam PF13581 Histidine kinase-like ATPase domain 20 147 1.0E-22 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HRM2_RS18725 b8a1d350829cf39a1757d7dea7c2a561 508 SUPERFAMILY SSF55729 114 311 1.54E-17 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS18725 b8a1d350829cf39a1757d7dea7c2a561 508 Gene3D G3DSA:3.40.630.30 175 310 2.8E-12 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS12670 e732ad25c25afb80c07583d4120f4650 77 Pfam PF11903 ParD-like antitoxin of type II bacterial toxin-antitoxin system 4 71 3.6E-20 T 22-04-2016 IPR021831 ParD-like antitoxin of type II bacterial toxin-antitoxin system HRM2_RS14050 51025c9e7bc936a1f383d9f943147f67 169 Pfam PF02754 Cysteine-rich domain 29 120 1.4E-9 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS14050 51025c9e7bc936a1f383d9f943147f67 169 PANTHER PTHR11921 1 123 8.7E-19 T 22-04-2016 HRM2_RS14050 51025c9e7bc936a1f383d9f943147f67 169 PANTHER PTHR11921:SF24 1 123 8.7E-19 T 22-04-2016 HRM2_RS08860 eeaf44b593f37532a4308bdf656939f5 191 SUPERFAMILY SSF55811 25 181 5.9E-29 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HRM2_RS08860 eeaf44b593f37532a4308bdf656939f5 191 ProSitePatterns PS00893 Nudix box signature. 86 107 - T 22-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 HRM2_RS08860 eeaf44b593f37532a4308bdf656939f5 191 Gene3D G3DSA:3.90.79.10 15 186 1.5E-37 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HRM2_RS08860 eeaf44b593f37532a4308bdf656939f5 191 PANTHER PTHR11839 51 173 2.0E-29 T 22-04-2016 HRM2_RS08860 eeaf44b593f37532a4308bdf656939f5 191 Pfam PF00293 NUDIX domain 52 165 4.2E-14 T 22-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 HRM2_RS19350 5c13b614dd37ecef17f420d931c59da0 278 Pfam PF13189 Cytidylate kinase-like family 3 167 9.5E-39 T 22-04-2016 IPR026865 Cytidylate kinase-like family MetaCyc: PWY-7205 HRM2_RS19350 5c13b614dd37ecef17f420d931c59da0 278 Gene3D G3DSA:3.40.50.300 1 184 1.8E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19350 5c13b614dd37ecef17f420d931c59da0 278 SUPERFAMILY SSF52540 17 186 6.86E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS09360 2c0f4930334cf2f2fe5d9311fbbfe081 111 Gene3D G3DSA:3.30.70.830 1 103 2.6E-38 T 22-04-2016 HRM2_RS09360 2c0f4930334cf2f2fe5d9311fbbfe081 111 PANTHER PTHR13799 2 105 1.1E-34 T 22-04-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 HRM2_RS09360 2c0f4930334cf2f2fe5d9311fbbfe081 111 SUPERFAMILY SSF102705 4 103 1.29E-22 T 22-04-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 HRM2_RS09360 2c0f4930334cf2f2fe5d9311fbbfe081 111 PANTHER PTHR13799:SF18 2 105 1.1E-34 T 22-04-2016 HRM2_RS00355 53d6daa2e646b72d907f4ef61f59ea6a 505 Pfam PF12225 Methylene-tetrahydrofolate reductase C terminal 398 478 9.3E-27 T 22-04-2016 IPR022026 Methylene-tetrahydrofolate reductase C-terminal HRM2_RS00355 53d6daa2e646b72d907f4ef61f59ea6a 505 Gene3D G3DSA:3.20.20.220 7 309 4.5E-44 T 22-04-2016 IPR029041 FAD-linked oxidoreductase-like HRM2_RS00355 53d6daa2e646b72d907f4ef61f59ea6a 505 Pfam PF02219 Methylenetetrahydrofolate reductase 12 290 1.9E-19 T 22-04-2016 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 HRM2_RS00355 53d6daa2e646b72d907f4ef61f59ea6a 505 SUPERFAMILY SSF51730 8 299 3.53E-45 T 22-04-2016 IPR029041 FAD-linked oxidoreductase-like HRM2_RS01930 b3ecddae6c5e8a5a358c79be55d5bf66 179 Pfam PF13302 Acetyltransferase (GNAT) domain 25 163 1.1E-7 T 22-04-2016 IPR000182 GNAT domain GO:0008080 HRM2_RS01930 b3ecddae6c5e8a5a358c79be55d5bf66 179 PANTHER PTHR33303 19 162 1.0E-11 T 22-04-2016 HRM2_RS01930 b3ecddae6c5e8a5a358c79be55d5bf66 179 PANTHER PTHR33303:SF4 19 162 1.0E-11 T 22-04-2016 HRM2_RS01930 b3ecddae6c5e8a5a358c79be55d5bf66 179 Gene3D G3DSA:3.40.630.30 25 166 1.8E-14 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS01930 b3ecddae6c5e8a5a358c79be55d5bf66 179 SUPERFAMILY SSF55729 21 166 3.6E-16 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS01965 666eaa81dad6e793da75920c01d9fa45 203 PANTHER PTHR10920 1 201 1.5E-63 T 22-04-2016 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 HRM2_RS01965 666eaa81dad6e793da75920c01d9fa45 203 PIRSF PIRSF005461 1 203 1.5E-65 T 22-04-2016 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 HRM2_RS01965 666eaa81dad6e793da75920c01d9fa45 203 SUPERFAMILY SSF53335 26 202 2.19E-35 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS01965 666eaa81dad6e793da75920c01d9fa45 203 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 7 202 24.306 T 22-04-2016 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 HRM2_RS01965 666eaa81dad6e793da75920c01d9fa45 203 Pfam PF01728 FtsJ-like methyltransferase 27 201 1.1E-49 T 22-04-2016 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 HRM2_RS01965 666eaa81dad6e793da75920c01d9fa45 203 Gene3D G3DSA:3.40.50.150 10 203 1.4E-58 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS05620 c9dd474104d5a219969890f4106e5ec9 131 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 27 3.8E-6 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site HRM2_RS05620 c9dd474104d5a219969890f4106e5ec9 131 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 8 28 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site HRM2_RS05620 c9dd474104d5a219969890f4106e5ec9 131 Pfam PF13633 Prokaryotic N-terminal methylation site 8 32 6.3E-7 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site HRM2_RS24830 2450a41fd6bddf328fb688817e17aef9 364 Pfam PF02663 FmdE, Molybdenum formylmethanofuran dehydrogenase operon 132 245 3.2E-12 T 22-04-2016 IPR003814 Formylmethanofuran dehydrogenase, subunit E domain HRM2_RS14160 549e4375eb1885a6cf6af80efa07612f 121 Pfam PF07238 PilZ domain 9 106 9.4E-6 T 22-04-2016 IPR009875 PilZ domain GO:0035438 HRM2_RS14160 549e4375eb1885a6cf6af80efa07612f 121 SUPERFAMILY SSF141371 3 109 1.51E-6 T 22-04-2016 HRM2_RS23890 6dd01b513041bd33fc16bfb5661b1c3d 244 Gene3D G3DSA:3.40.50.300 67 226 2.0E-27 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23890 6dd01b513041bd33fc16bfb5661b1c3d 244 SMART SM00382 96 232 4.7E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain HRM2_RS23890 6dd01b513041bd33fc16bfb5661b1c3d 244 SUPERFAMILY SSF52540 63 226 1.1E-23 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS23890 6dd01b513041bd33fc16bfb5661b1c3d 244 PIRSF PIRSF003073 1 244 1.4E-82 T 22-04-2016 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein HRM2_RS23890 6dd01b513041bd33fc16bfb5661b1c3d 244 PANTHER PTHR30050 10 242 1.4E-57 T 22-04-2016 HRM2_RS23890 6dd01b513041bd33fc16bfb5661b1c3d 244 Pfam PF01695 IstB-like ATP binding protein 52 228 1.7E-57 T 22-04-2016 IPR002611 IstB-like ATP-binding protein GO:0005524 HRM2_RS10020 5322faae82587261c73fcdbfb77c8f8b 604 Pfam PF11741 AMIN domain 49 114 4.9E-10 T 22-04-2016 IPR021731 AMIN domain HRM2_RS04380 49bfab6174f8e188e860db19e7466c37 263 Gene3D G3DSA:3.40.50.1820 22 250 5.4E-30 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS04380 49bfab6174f8e188e860db19e7466c37 263 SUPERFAMILY SSF53474 13 256 2.97E-35 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS04380 49bfab6174f8e188e860db19e7466c37 263 PANTHER PTHR12277 28 263 4.0E-36 T 22-04-2016 HRM2_RS04380 49bfab6174f8e188e860db19e7466c37 263 Pfam PF12146 Serine aminopeptidase, S33 61 170 6.4E-13 T 22-04-2016 IPR022742 Serine aminopeptidase, S33 HRM2_RS24075 58b74f35025af2a1f43e9146aeb59a48 345 SUPERFAMILY SSF54197 194 338 1.33E-8 T 22-04-2016 IPR011146 HIT-like domain GO:0003824 HRM2_RS24075 58b74f35025af2a1f43e9146aeb59a48 345 Gene3D G3DSA:3.30.428.10 148 335 3.5E-16 T 22-04-2016 IPR011146 HIT-like domain GO:0003824 HRM2_RS24075 58b74f35025af2a1f43e9146aeb59a48 345 SUPERFAMILY SSF54197 22 179 5.1E-18 T 22-04-2016 IPR011146 HIT-like domain GO:0003824 HRM2_RS05430 622264e36fd43a2ba6a7cbe445164b5c 193 PANTHER PTHR40278 1 175 1.4E-19 T 22-04-2016 HRM2_RS05430 622264e36fd43a2ba6a7cbe445164b5c 193 Pfam PF05137 Fimbrial assembly protein (PilN) 101 177 3.4E-17 T 22-04-2016 IPR007813 Fimbrial assembly PilN HRM2_RS20090 0a33ef0b95b238b77b1da06a10d74462 66 Pfam PF11127 Protein of unknown function (DUF2892) 2 56 2.7E-13 T 22-04-2016 IPR021309 Protein of unknown function DUF2892 HRM2_RS24410 8ad73fd34758e51ea0d20c355cfe5c5b 245 Pfam PF12281 Nucleotidyltransferase 113 221 2.3E-28 T 22-04-2016 IPR022550 Nucleotidyltransferase 8 HRM2_RS09845 51620f4a3555d2d3edbc2f659351ce13 379 SUPERFAMILY SSF53756 78 353 1.78E-18 T 22-04-2016 HRM2_RS09845 51620f4a3555d2d3edbc2f659351ce13 379 Pfam PF13692 Glycosyl transferases group 1 216 347 3.3E-11 T 22-04-2016 HRM2_RS12255 518ad2b38d55c23e691bf3ab8d61cfbd 738 SUPERFAMILY SSF52540 214 338 5.79E-21 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12255 518ad2b38d55c23e691bf3ab8d61cfbd 738 SUPERFAMILY SSF52540 50 128 5.79E-21 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12255 518ad2b38d55c23e691bf3ab8d61cfbd 738 Gene3D G3DSA:3.40.50.300 214 311 4.8E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12255 518ad2b38d55c23e691bf3ab8d61cfbd 738 Gene3D G3DSA:3.40.50.300 52 128 4.8E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12255 518ad2b38d55c23e691bf3ab8d61cfbd 738 Pfam PF00350 Dynamin family 57 281 7.0E-13 T 22-04-2016 IPR022812 Dynamin superfamily HRM2_RS19115 aa7642df509b82316f430206ec6916f3 352 PANTHER PTHR33376 4 350 2.4E-47 T 22-04-2016 HRM2_RS19115 aa7642df509b82316f430206ec6916f3 352 SUPERFAMILY SSF53850 133 275 8.15E-7 T 22-04-2016 HRM2_RS19115 aa7642df509b82316f430206ec6916f3 352 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 49 329 8.6E-44 T 22-04-2016 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 HRM2_RS02010 c05cbfcd0ee608723664998bb51da353 480 Pfam PF11855 Protein of unknown function (DUF3375) 11 478 1.5E-150 T 22-04-2016 IPR021804 Protein of unknown function DUF3375 HRM2_RS05130 d2a1a60cc7b0e504e7c87dd69f395b82 251 Pfam PF05023 Phytochelatin synthase 50 230 1.3E-9 T 22-04-2016 IPR007719 Phytochelatin synthase GO:0010038|GO:0016756|GO:0046872|GO:0046938 MetaCyc: PWY-6745 HRM2_RS05130 d2a1a60cc7b0e504e7c87dd69f395b82 251 SUPERFAMILY SSF54001 45 230 6.87E-12 T 22-04-2016 HRM2_RS18660 60f4df1de72050ab3014fb3381a62af1 306 SUPERFAMILY SSF52402 167 300 3.35E-17 T 22-04-2016 HRM2_RS18660 60f4df1de72050ab3014fb3381a62af1 306 PRINTS PR01438 Universal stress protein signature 284 306 8.88E-6 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS18660 60f4df1de72050ab3014fb3381a62af1 306 PRINTS PR01438 Universal stress protein signature 166 184 8.88E-6 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS18660 60f4df1de72050ab3014fb3381a62af1 306 PRINTS PR01438 Universal stress protein signature 266 278 8.88E-6 T 22-04-2016 IPR006015 Universal stress protein A HRM2_RS18660 60f4df1de72050ab3014fb3381a62af1 306 Pfam PF00582 Universal stress protein family 167 299 2.3E-17 T 22-04-2016 IPR006016 UspA GO:0006950 HRM2_RS18660 60f4df1de72050ab3014fb3381a62af1 306 Pfam PF00582 Universal stress protein family 9 149 2.8E-8 T 22-04-2016 IPR006016 UspA GO:0006950 HRM2_RS18660 60f4df1de72050ab3014fb3381a62af1 306 Gene3D G3DSA:3.40.50.620 9 149 2.1E-16 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS18660 60f4df1de72050ab3014fb3381a62af1 306 Gene3D G3DSA:3.40.50.620 167 300 9.4E-21 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS18660 60f4df1de72050ab3014fb3381a62af1 306 SUPERFAMILY SSF52402 9 150 5.27E-14 T 22-04-2016 HRM2_RS03220 2d1695e7a932dbe99212cee34e72c023 218 Pfam PF03692 Putative zinc- or iron-chelating domain 36 140 4.8E-6 T 22-04-2016 IPR005358 Putative zinc- or iron-chelating domain containing protein HRM2_RS06650 2c7aa32c1bb56bfa82ad38bf490955ac 129 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 1 80 5.3E-12 T 22-04-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 HRM2_RS06650 2c7aa32c1bb56bfa82ad38bf490955ac 129 SUPERFAMILY SSF51344 1 83 1.26E-14 T 22-04-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 HRM2_RS06650 2c7aa32c1bb56bfa82ad38bf490955ac 129 TIGRFAM TIGR03166 alt_F1F0_F1_eps: alternate F1F0 ATPase, F1 subunit epsilon 3 123 2.8E-31 T 22-04-2016 IPR024037 Alternate F1F0 ATPase, F1 subunit epsilon HRM2_RS06650 2c7aa32c1bb56bfa82ad38bf490955ac 129 Gene3D G3DSA:2.60.15.10 1 85 4.7E-10 T 22-04-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 HRM2_RS17275 09ba38cbc4931cd186a82eedd356b0a5 265 PANTHER PTHR30269 1 264 2.9E-86 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 HRM2_RS17275 09ba38cbc4931cd186a82eedd356b0a5 265 Pfam PF01925 Sulfite exporter TauE/SafE 9 260 1.1E-55 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 HRM2_RS17275 09ba38cbc4931cd186a82eedd356b0a5 265 PANTHER PTHR30269:SF18 1 264 2.9E-86 T 22-04-2016 HRM2_RS19340 3be63521348a62559d9f13b23f891db1 253 Pfam PF17131 Outer membrane lipoprotein-sorting protein 76 248 2.8E-39 T 22-04-2016 IPR033399 Putative outer membrane lipoprotein-sorting protein HRM2_RS19340 3be63521348a62559d9f13b23f891db1 253 Gene3D G3DSA:2.50.20.10 28 249 4.7E-54 T 22-04-2016 HRM2_RS07495 cefcb3eec3fd783c05e9dce4c963ffff 171 SUPERFAMILY SSF46626 74 167 1.13E-12 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 HRM2_RS07495 cefcb3eec3fd783c05e9dce4c963ffff 171 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 84 163 7.9E-11 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 HRM2_RS07495 cefcb3eec3fd783c05e9dce4c963ffff 171 Gene3D G3DSA:1.10.760.10 75 168 2.0E-12 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 HRM2_RS24115 7f161246ae8f8ae47d18bc3b3afa59d0 290 PANTHER PTHR30482:SF10 2 290 5.3E-87 T 22-04-2016 HRM2_RS24115 7f161246ae8f8ae47d18bc3b3afa59d0 290 Pfam PF02653 Branched-chain amino acid transport system / permease component 6 277 2.1E-50 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 HRM2_RS24115 7f161246ae8f8ae47d18bc3b3afa59d0 290 PANTHER PTHR30482 2 290 5.3E-87 T 22-04-2016 HRM2_RS15340 8a10960b3f6591e122b0ceae2bdf26ab 297 PANTHER PTHR30151 52 286 2.9E-53 T 22-04-2016 HRM2_RS15340 8a10960b3f6591e122b0ceae2bdf26ab 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 283 2.5E-18 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS15340 8a10960b3f6591e122b0ceae2bdf26ab 297 SUPERFAMILY SSF161098 97 282 2.09E-29 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS15340 8a10960b3f6591e122b0ceae2bdf26ab 297 Gene3D G3DSA:1.10.3720.10 96 287 2.8E-22 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HRM2_RS15340 8a10960b3f6591e122b0ceae2bdf26ab 297 PANTHER PTHR30151:SF7 52 286 2.9E-53 T 22-04-2016 HRM2_RS00450 b30ae6d7bd89e0073ae787e716a3b3d9 213 Pfam PF01794 Ferric reductase like transmembrane component 45 166 6.0E-12 T 22-04-2016 IPR013130 Ferric reductase transmembrane component-like domain HRM2_RS08560 ed48ed91fc0f041f7c017f44e34d6de8 200 Pfam PF05908 Poly-gamma-glutamate hydrolase 5 192 4.6E-68 T 22-04-2016 IPR008585 Poly-gamma-glutamate hydrolase HRM2_RS08790 1a1ad20201ea39e8fb11234740e09e6b 335 Gene3D G3DSA:3.40.50.1820 47 333 9.0E-36 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS08790 1a1ad20201ea39e8fb11234740e09e6b 335 Pfam PF12146 Serine aminopeptidase, S33 66 320 3.7E-44 T 22-04-2016 IPR022742 Serine aminopeptidase, S33 HRM2_RS08790 1a1ad20201ea39e8fb11234740e09e6b 335 PANTHER PTHR11614:SF100 40 333 8.8E-70 T 22-04-2016 HRM2_RS08790 1a1ad20201ea39e8fb11234740e09e6b 335 PANTHER PTHR11614 40 333 8.8E-70 T 22-04-2016 HRM2_RS08790 1a1ad20201ea39e8fb11234740e09e6b 335 SUPERFAMILY SSF53474 42 329 2.68E-39 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS20755 a6a0edfd1e067e2633f2c8269f61244f 149 SUPERFAMILY SSF54637 1 142 5.36E-42 T 22-04-2016 IPR029069 HotDog domain HRM2_RS20755 a6a0edfd1e067e2633f2c8269f61244f 149 Gene3D G3DSA:3.10.129.10 5 134 4.6E-46 T 22-04-2016 IPR029069 HotDog domain HRM2_RS20755 a6a0edfd1e067e2633f2c8269f61244f 149 PANTHER PTHR13078 1 134 1.8E-41 T 22-04-2016 HRM2_RS20755 a6a0edfd1e067e2633f2c8269f61244f 149 Pfam PF01575 MaoC like domain 11 115 3.5E-26 T 22-04-2016 IPR002539 MaoC-like domain HRM2_RS20160 2d45dfee40f69ccda6b18e07a09b6135 204 SMART SM00287 136 199 1.2E-7 T 22-04-2016 IPR003646 SH3-like domain, bacterial-type HRM2_RS20160 2d45dfee40f69ccda6b18e07a09b6135 204 Pfam PF08239 Bacterial SH3 domain 146 195 6.3E-7 T 22-04-2016 IPR003646 SH3-like domain, bacterial-type HRM2_RS12175 7379a9c385d2f97c4a1c4e1ce940aa0a 455 SUPERFAMILY SSF55729 150 285 2.32E-7 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS12175 7379a9c385d2f97c4a1c4e1ce940aa0a 455 Gene3D G3DSA:3.40.630.30 151 282 1.2E-6 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS01950 706d5958eba564e98757ed60dfc2041b 70 Pfam PF13396 Phospholipase_D-nuclease N-terminal 16 57 2.4E-8 T 22-04-2016 IPR027379 Cardiolipin synthase N-terminal HRM2_RS09550 fcd218f9a35ea95834cceca27afa956a 483 Pfam PF00665 Integrase core domain 97 222 3.2E-7 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 HRM2_RS09550 fcd218f9a35ea95834cceca27afa956a 483 Gene3D G3DSA:3.30.420.10 95 257 9.8E-5 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS17140 989922d4888d9e238cdaff2d83b8f546 217 Pfam PF03358 NADPH-dependent FMN reductase 4 135 1.1E-16 T 22-04-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 HRM2_RS17140 989922d4888d9e238cdaff2d83b8f546 217 Gene3D G3DSA:3.40.50.360 4 209 2.1E-36 T 22-04-2016 IPR029039 Flavoprotein-like domain HRM2_RS17140 989922d4888d9e238cdaff2d83b8f546 217 SUPERFAMILY SSF52218 4 156 1.14E-27 T 22-04-2016 IPR029039 Flavoprotein-like domain HRM2_RS17140 989922d4888d9e238cdaff2d83b8f546 217 PANTHER PTHR10204 3 122 1.9E-19 T 22-04-2016 HRM2_RS17140 989922d4888d9e238cdaff2d83b8f546 217 PANTHER PTHR10204:SF5 3 122 1.9E-19 T 22-04-2016 HRM2_RS20260 edfa8c85b1df898860243868f40191e9 109 PANTHER PTHR35113 1 109 1.0E-26 T 22-04-2016 HRM2_RS20260 edfa8c85b1df898860243868f40191e9 109 SUPERFAMILY SSF57662 3 104 2.75E-31 T 22-04-2016 IPR004209 Ferredoxin thioredoxin reductase catalytic beta subunit GO:0016730|GO:0055114 HRM2_RS20260 edfa8c85b1df898860243868f40191e9 109 Pfam PF02943 Ferredoxin thioredoxin reductase catalytic beta chain 5 93 8.1E-23 T 22-04-2016 IPR004209 Ferredoxin thioredoxin reductase catalytic beta subunit GO:0016730|GO:0055114 HRM2_RS20260 edfa8c85b1df898860243868f40191e9 109 PANTHER PTHR35113:SF1 1 109 1.0E-26 T 22-04-2016 HRM2_RS20260 edfa8c85b1df898860243868f40191e9 109 Gene3D G3DSA:3.90.460.10 3 107 3.8E-30 T 22-04-2016 IPR004209 Ferredoxin thioredoxin reductase catalytic beta subunit GO:0016730|GO:0055114 HRM2_RS03665 caa5abc358ed0796768dd88282aac4cb 550 PANTHER PTHR30047:SF2 23 540 1.9E-141 T 22-04-2016 HRM2_RS03665 caa5abc358ed0796768dd88282aac4cb 550 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 29 533 5.2E-153 T 22-04-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 HRM2_RS03665 caa5abc358ed0796768dd88282aac4cb 550 PANTHER PTHR30047 23 540 1.9E-141 T 22-04-2016 HRM2_RS21375 3feb8588456ac8c63aebc841ebdf4f66 107 Pfam PF11287 Protein of unknown function (DUF3088) 1 101 4.1E-32 T 22-04-2016 IPR021439 Protein of unknown function DUF3088 HRM2_RS24975 4e56a340e77efc265b9d6544d308ffe5 342 Gene3D G3DSA:2.70.70.10 203 340 8.8E-43 T 22-04-2016 HRM2_RS24975 4e56a340e77efc265b9d6544d308ffe5 342 SUPERFAMILY SSF51261 151 338 9.94E-47 T 22-04-2016 IPR011055 Duplicated hybrid motif HRM2_RS24975 4e56a340e77efc265b9d6544d308ffe5 342 Pfam PF01551 Peptidase family M23 240 334 5.0E-28 T 22-04-2016 IPR016047 Peptidase M23 HRM2_RS24975 4e56a340e77efc265b9d6544d308ffe5 342 PANTHER PTHR21666 15 338 4.4E-39 T 22-04-2016 HRM2_RS21795 8401b7718cc286f13f35bbc5ab2e6f95 489 Pfam PF06253 Trimethylamine methyltransferase (MTTB) 5 474 1.9E-98 T 22-04-2016 IPR010426 Trimethylamine methyltransferase GO:0008168|GO:0015948 KEGG: 00680+2.1.1.250|MetaCyc: PWY-5250|UniPathway: UPA00645 HRM2_RS18845 d42715aeb9de868209fc90564368aa4d 160 Gene3D G3DSA:3.60.20.10 3 116 8.8E-5 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal HRM2_RS04390 f5e28635223a4db50a77a500e042ecb8 568 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 492 540 3.7E-7 T 22-04-2016 IPR003776 YcaO-like domain HRM2_RS04390 f5e28635223a4db50a77a500e042ecb8 568 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 248 467 8.5E-34 T 22-04-2016 IPR003776 YcaO-like domain HRM2_RS06765 81a5d55c04e7de9bf10625049fa8294e 118 ProDom PD053081 COIL MM0410 AF2262 COILED 61 92 0.003 T 22-04-2016 HRM2_RS05720 a913c5c0d82d7fa490122ac79dbecceb 103 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 87 6.6E-5 T 22-04-2016 IPR000361 FeS cluster biogenesis HRM2_RS05720 a913c5c0d82d7fa490122ac79dbecceb 103 SUPERFAMILY SSF89360 1 79 1.47E-8 T 22-04-2016 IPR000361 FeS cluster biogenesis HRM2_RS05720 a913c5c0d82d7fa490122ac79dbecceb 103 Gene3D G3DSA:2.60.300.12 1 79 3.3E-10 T 22-04-2016 IPR000361 FeS cluster biogenesis HRM2_RS03340 6cd0cc72c6ef262f1d854687a9896a6f 166 SUPERFAMILY SSF47240 1 152 2.2E-16 T 22-04-2016 IPR009078 Ferritin-like superfamily HRM2_RS03340 6cd0cc72c6ef262f1d854687a9896a6f 166 Gene3D G3DSA:1.20.1260.10 2 148 4.2E-20 T 22-04-2016 IPR012347 Ferritin-related HRM2_RS03340 6cd0cc72c6ef262f1d854687a9896a6f 166 Pfam PF02915 Rubrerythrin 5 141 4.0E-7 T 22-04-2016 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 HRM2_RS04220 9a67dfa8176590f9916858b059eef6fe 239 Pfam PF01925 Sulfite exporter TauE/SafE 6 233 1.2E-21 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 HRM2_RS06145 da9fdf1fe4b9675f7fa9900ebc21e388 139 Gene3D G3DSA:2.60.120.10 3 127 6.7E-21 T 22-04-2016 IPR014710 RmlC-like jelly roll fold HRM2_RS06145 da9fdf1fe4b9675f7fa9900ebc21e388 139 Pfam PF00027 Cyclic nucleotide-binding domain 27 111 1.9E-14 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain HRM2_RS06145 da9fdf1fe4b9675f7fa9900ebc21e388 139 SMART SM00100 8 124 2.3E-13 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain HRM2_RS06145 da9fdf1fe4b9675f7fa9900ebc21e388 139 SUPERFAMILY SSF51206 3 126 2.62E-22 T 22-04-2016 IPR018490 Cyclic nucleotide-binding-like HRM2_RS11295 0fa0c24413fbfa01aab6c8adc1ff4719 296 Pfam PF02754 Cysteine-rich domain 3 87 3.5E-14 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS11295 0fa0c24413fbfa01aab6c8adc1ff4719 296 Pfam PF02754 Cysteine-rich domain 150 234 1.9E-9 T 22-04-2016 IPR004017 Cysteine-rich domain HRM2_RS11295 0fa0c24413fbfa01aab6c8adc1ff4719 296 PANTHER PTHR32479:SF12 1 292 1.1E-46 T 22-04-2016 HRM2_RS11295 0fa0c24413fbfa01aab6c8adc1ff4719 296 PANTHER PTHR32479 1 292 1.1E-46 T 22-04-2016 HRM2_RS15615 d45a3d4e9600b24b768b84cb4679b94d 170 Pfam PF14361 RsbT co-antagonist protein rsbRD N-terminal domain 7 108 1.6E-19 T 22-04-2016 IPR025751 RsbT co-antagonist protein RsbRD, N-terminal domain HRM2_RS03935 ef9edb516f61eddc766dcb9469f6145c 223 Pfam PF03016 Exostosin family 54 175 3.7E-10 T 22-04-2016 IPR004263 Exostosin-like HRM2_RS09915 6f44fcc27bfb4d7ec772ce2806372143 423 Gene3D G3DSA:3.40.50.20 35 132 9.3E-7 T 22-04-2016 IPR016185 Pre-ATP-grasp domain HRM2_RS09915 6f44fcc27bfb4d7ec772ce2806372143 423 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 258 299 6.3E-6 T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HRM2_RS09915 6f44fcc27bfb4d7ec772ce2806372143 423 SUPERFAMILY SSF56059 130 303 8.49E-23 T 22-04-2016 HRM2_RS09915 6f44fcc27bfb4d7ec772ce2806372143 423 Gene3D G3DSA:3.30.470.20 133 314 4.8E-21 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS01675 57fab3c0b32a23e56223b9948371cf0f 133 Pfam PF13673 Acetyltransferase (GNAT) domain 37 122 1.1E-12 T 22-04-2016 IPR000182 GNAT domain GO:0008080 HRM2_RS01675 57fab3c0b32a23e56223b9948371cf0f 133 SUPERFAMILY SSF55729 1 123 4.56E-21 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS01675 57fab3c0b32a23e56223b9948371cf0f 133 Gene3D G3DSA:3.40.630.30 1 123 1.8E-23 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS13460 a648c47a518bd08f51191ad78b7c7afb 171 Pfam PF04390 Lipopolysaccharide-assembly 12 167 1.3E-15 T 22-04-2016 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 HRM2_RS22135 2b18f37c1df14e771f03d8adfd852bc3 228 Gene3D G3DSA:3.40.50.1820 1 225 1.8E-25 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS22135 2b18f37c1df14e771f03d8adfd852bc3 228 SUPERFAMILY SSF53474 2 225 4.85E-33 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS22135 2b18f37c1df14e771f03d8adfd852bc3 228 Pfam PF01738 Dienelactone hydrolase family 79 225 3.7E-7 T 22-04-2016 IPR002925 Dienelactone hydrolase GO:0016787 HRM2_RS22135 2b18f37c1df14e771f03d8adfd852bc3 228 PANTHER PTHR13136:SF4 1 224 3.6E-35 T 22-04-2016 HRM2_RS22135 2b18f37c1df14e771f03d8adfd852bc3 228 PANTHER PTHR13136 1 224 3.6E-35 T 22-04-2016 IPR026555 KAT8 regulatory NSL complex subunit 3/Testis-expressed sequence 30 protein HRM2_RS17090 467daa773e770b381f0373b74fb76831 313 Pfam PF02653 Branched-chain amino acid transport system / permease component 33 297 2.2E-41 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 HRM2_RS17090 467daa773e770b381f0373b74fb76831 313 PANTHER PTHR32196 1 301 1.8E-71 T 22-04-2016 HRM2_RS17090 467daa773e770b381f0373b74fb76831 313 PANTHER PTHR32196:SF21 1 301 1.8E-71 T 22-04-2016 HRM2_RS12505 5790135bbc15bf3d8e936b42b85634e6 131 Pfam PF07238 PilZ domain 3 98 3.0E-9 T 22-04-2016 IPR009875 PilZ domain GO:0035438 HRM2_RS25085 6dc25fe9c0debf0e0df3e60dfb39f8c3 232 Pfam PF03692 Putative zinc- or iron-chelating domain 20 119 1.7E-10 T 22-04-2016 IPR005358 Putative zinc- or iron-chelating domain containing protein HRM2_RS07700 514b8b15a951270771d4e1336297be1b 253 PANTHER PTHR11931 1 248 1.1E-154 T 22-04-2016 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484|UniPathway: UPA00109 HRM2_RS07700 514b8b15a951270771d4e1336297be1b 253 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 129 203 9.2E-5 T 22-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 HRM2_RS07700 514b8b15a951270771d4e1336297be1b 253 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 123 3.7E-27 T 22-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 HRM2_RS07700 514b8b15a951270771d4e1336297be1b 253 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 22-04-2016 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 UniPathway: UPA00109 HRM2_RS07700 514b8b15a951270771d4e1336297be1b 253 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 228 45.106 T 22-04-2016 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484|UniPathway: UPA00109 HRM2_RS07700 514b8b15a951270771d4e1336297be1b 253 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 3 244 1.4E-118 T 22-04-2016 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484|UniPathway: UPA00109 HRM2_RS07700 514b8b15a951270771d4e1336297be1b 253 SMART SM00855 3 189 2.0E-26 T 22-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 HRM2_RS07700 514b8b15a951270771d4e1336297be1b 253 SUPERFAMILY SSF53254 1 244 5.1E-76 T 22-04-2016 IPR029033 Histidine phosphatase superfamily HRM2_RS07700 514b8b15a951270771d4e1336297be1b 253 Gene3D G3DSA:3.40.50.1240 1 247 9.9E-95 T 22-04-2016 IPR029033 Histidine phosphatase superfamily HRM2_RS09855 b2eb1f246a0a158dbf434e066c7b1d86 515 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 352 494 5.9E-11 T 22-04-2016 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain HRM2_RS09855 b2eb1f246a0a158dbf434e066c7b1d86 515 Pfam PF13440 Polysaccharide biosynthesis protein 100 332 1.9E-9 T 22-04-2016 HRM2_RS09855 b2eb1f246a0a158dbf434e066c7b1d86 515 PANTHER PTHR30250 1 513 1.7E-13 T 22-04-2016 HRM2_RS09220 1e805a6073c29905409b3b3185d1e8fe 291 Gene3D G3DSA:3.40.50.2020 104 290 9.5E-25 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like HRM2_RS09220 1e805a6073c29905409b3b3185d1e8fe 291 PANTHER PTHR11907 69 290 1.0E-38 T 22-04-2016 HRM2_RS09220 1e805a6073c29905409b3b3185d1e8fe 291 PANTHER PTHR11907:SF9 69 290 1.0E-38 T 22-04-2016 HRM2_RS09220 1e805a6073c29905409b3b3185d1e8fe 291 SUPERFAMILY SSF53271 116 289 1.44E-22 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like HRM2_RS25645 5eff9fcfdf2359695406c196701f6e7b 927 Pfam PF07603 Protein of unknown function (DUF1566) 255 377 2.0E-24 T 22-04-2016 IPR011460 Protein of unknown function DUF1566 HRM2_RS25645 5eff9fcfdf2359695406c196701f6e7b 927 Pfam PF07603 Protein of unknown function (DUF1566) 751 819 1.3E-15 T 22-04-2016 IPR011460 Protein of unknown function DUF1566 HRM2_RS25645 5eff9fcfdf2359695406c196701f6e7b 927 Pfam PF07603 Protein of unknown function (DUF1566) 114 239 4.7E-22 T 22-04-2016 IPR011460 Protein of unknown function DUF1566 HRM2_RS25645 5eff9fcfdf2359695406c196701f6e7b 927 Pfam PF07603 Protein of unknown function (DUF1566) 526 645 7.7E-22 T 22-04-2016 IPR011460 Protein of unknown function DUF1566 HRM2_RS13430 70fb544451f4461bd9df144a57fc8041 148 Pfam PF07291 Methylamine utilisation protein MauE 8 140 2.1E-21 T 22-04-2016 IPR009908 Methylamine utilisation protein, MauE GO:0016021|GO:0030416 UniPathway: UPA00895 HRM2_RS09455 aed81093b0c6b1537be64b567364ce02 199 Gene3D G3DSA:3.90.79.10 82 194 8.4E-5 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HRM2_RS15365 6acdf73e0a365e4b3407cffc730a993e 109 Gene3D G3DSA:1.20.58.340 44 99 1.4E-4 T 22-04-2016 HRM2_RS05180 af206a0c91c327b1cff2a9608c2756f2 426 Pfam PF13535 ATP-grasp domain 151 305 1.4E-11 T 22-04-2016 HRM2_RS05180 af206a0c91c327b1cff2a9608c2756f2 426 SUPERFAMILY SSF56059 114 326 4.95E-25 T 22-04-2016 HRM2_RS05180 af206a0c91c327b1cff2a9608c2756f2 426 Gene3D G3DSA:3.30.470.20 109 327 9.2E-23 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HRM2_RS00650 67ae871b55bc6425ae519b0518873695 213 SUPERFAMILY SSF53335 9 163 5.02E-32 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS00650 67ae871b55bc6425ae519b0518873695 213 Gene3D G3DSA:3.40.50.150 9 161 3.5E-32 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS00650 67ae871b55bc6425ae519b0518873695 213 Pfam PF13649 Methyltransferase domain 52 146 5.9E-19 T 22-04-2016 HRM2_RS00650 67ae871b55bc6425ae519b0518873695 213 PANTHER PTHR10108 8 153 7.0E-30 T 22-04-2016 HRM2_RS17240 39703236c76c03dd7ef52d4a96388616 819 SUPERFAMILY SSF102114 205 427 1.7E-14 T 22-04-2016 HRM2_RS17240 39703236c76c03dd7ef52d4a96388616 819 PANTHER PTHR30538 199 441 4.8E-41 T 22-04-2016 HRM2_RS17240 39703236c76c03dd7ef52d4a96388616 819 PANTHER PTHR30538 459 535 4.8E-41 T 22-04-2016 HRM2_RS17240 39703236c76c03dd7ef52d4a96388616 819 Pfam PF04055 Radical SAM superfamily 215 320 7.0E-8 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS17240 39703236c76c03dd7ef52d4a96388616 819 Pfam PF13394 4Fe-4S single cluster domain 209 280 2.8E-8 T 22-04-2016 HRM2_RS17240 39703236c76c03dd7ef52d4a96388616 819 Gene3D G3DSA:3.20.20.70 207 400 1.9E-14 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS24835 7a2898908e33d0a67e5eafa32c9c35be 817 PANTHER PTHR23501 450 797 2.4E-15 T 22-04-2016 HRM2_RS24835 7a2898908e33d0a67e5eafa32c9c35be 817 Gene3D G3DSA:1.20.1250.20 635 802 1.6E-16 T 22-04-2016 HRM2_RS24835 7a2898908e33d0a67e5eafa32c9c35be 817 Gene3D G3DSA:1.20.1250.20 416 597 1.6E-21 T 22-04-2016 HRM2_RS24835 7a2898908e33d0a67e5eafa32c9c35be 817 SUPERFAMILY SSF103473 415 798 4.05E-42 T 22-04-2016 IPR020846 Major facilitator superfamily domain HRM2_RS24835 7a2898908e33d0a67e5eafa32c9c35be 817 Pfam PF07690 Major Facilitator Superfamily 415 736 1.2E-25 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HRM2_RS16610 be98de47b71c37a376f7e30f21e713b3 126 Gene3D G3DSA:1.10.10.10 65 115 1.3E-6 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS16610 be98de47b71c37a376f7e30f21e713b3 126 SUPERFAMILY SSF46785 62 117 8.91E-6 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS20775 41b41afb1ce61e0cc88c495abe5d5464 147 Pfam PF04024 PspC domain 33 87 2.1E-10 T 22-04-2016 IPR007168 Phage shock protein, PspC, N-terminal HRM2_RS05110 a36cb5730a6c6a25b229f60b10ff5181 216 Pfam PF01794 Ferric reductase like transmembrane component 59 169 1.6E-6 T 22-04-2016 IPR013130 Ferric reductase transmembrane component-like domain HRM2_RS24930 a8639a8b576d398d863701476fc525b9 97 SUPERFAMILY SSF55166 3 34 2.9E-7 T 22-04-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain HRM2_RS24930 a8639a8b576d398d863701476fc525b9 97 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 3 32 3.7E-9 T 22-04-2016 HRM2_RS12090 36d52e1f2ddab713433c7459bed47c7c 188 Pfam PF04143 Sulphur transport 2 177 9.3E-16 T 22-04-2016 IPR007272 Sulphur transport domain HRM2_RS16685 3b9088d960d1531ffe44677f23548f39 310 PANTHER PTHR11795 6 310 3.8E-114 T 22-04-2016 HRM2_RS16685 3b9088d960d1531ffe44677f23548f39 310 PANTHER PTHR11795:SF371 6 310 3.8E-114 T 22-04-2016 HRM2_RS16685 3b9088d960d1531ffe44677f23548f39 310 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 294 2.4E-48 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 HRM2_RS06945 4aad153523bbc6cc4114d5efc33c5790 348 PIRSF PIRSF039026 1 348 9.2E-107 T 22-04-2016 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like HRM2_RS06945 4aad153523bbc6cc4114d5efc33c5790 348 PANTHER PTHR33376 1 339 8.2E-73 T 22-04-2016 HRM2_RS06945 4aad153523bbc6cc4114d5efc33c5790 348 PANTHER PTHR33376:SF5 1 339 8.2E-73 T 22-04-2016 HRM2_RS06945 4aad153523bbc6cc4114d5efc33c5790 348 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 33 315 1.1E-44 T 22-04-2016 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 HRM2_RS09945 a8a0305bff13689b459e41e9a991c3b7 410 Pfam PF04892 VanZ like family 8 117 3.4E-10 T 22-04-2016 IPR006976 VanZ-like HRM2_RS05485 8f322136b21d0d6678a35c22a3ad6f3d 193 Pfam PF09335 SNARE associated Golgi protein 38 154 2.8E-11 T 22-04-2016 IPR032816 SNARE associated Golgi protein HRM2_RS18885 5cd1e69efeff6755e80eaa3537189e27 617 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 163 606 7.0E-65 T 22-04-2016 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 HRM2_RS18885 5cd1e69efeff6755e80eaa3537189e27 617 Pfam PF00939 Sodium:sulfate symporter transmembrane region 169 606 2.0E-47 T 22-04-2016 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 HRM2_RS18885 5cd1e69efeff6755e80eaa3537189e27 617 PANTHER PTHR10283 133 606 3.3E-68 T 22-04-2016 HRM2_RS17105 8ec4ffac7d600ee9ac251fabf2191364 210 Pfam PF12654 Domain of unknown function (DUF3786) 22 197 1.1E-48 T 22-04-2016 IPR024264 Domain of unknown function DUF3786 HRM2_RS22925 653cb0abf7da336b157f5e6c618e9170 69 Pfam PF04102 SlyX 3 69 2.3E-23 T 22-04-2016 IPR007236 SlyX HRM2_RS22925 653cb0abf7da336b157f5e6c618e9170 69 PANTHER PTHR36508 3 69 3.7E-15 T 22-04-2016 HRM2_RS22925 653cb0abf7da336b157f5e6c618e9170 69 Hamap MF_00715 Protein SlyX [slyX]. 1 69 14.142 T 22-04-2016 IPR007236 SlyX HRM2_RS22925 653cb0abf7da336b157f5e6c618e9170 69 Gene3D G3DSA:1.20.5.300 3 47 1.5E-15 T 22-04-2016 HRM2_RS24960 c4a58978970bf0222dd88bcd55693d4a 599 Pfam PF12704 MacB-like periplasmic core domain 30 198 2.8E-8 T 22-04-2016 IPR025857 MacB-like periplasmic core domain HRM2_RS24960 c4a58978970bf0222dd88bcd55693d4a 599 Pfam PF02687 FtsX-like permease family 483 592 1.0E-7 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 HRM2_RS24960 c4a58978970bf0222dd88bcd55693d4a 599 PANTHER PTHR30572 418 599 1.3E-14 T 22-04-2016 HRM2_RS24025 c53260cd25e61ca11464f6c352707c89 239 Gene3D G3DSA:3.40.50.1010 5 143 1.1E-30 T 22-04-2016 IPR029060 PIN domain-like HRM2_RS24025 c53260cd25e61ca11464f6c352707c89 239 Pfam PF01936 NYN domain 8 141 8.7E-32 T 22-04-2016 IPR021139 NYN domain, limkain-b1-type HRM2_RS24025 c53260cd25e61ca11464f6c352707c89 239 Pfam PF12872 OST-HTH/LOTUS domain 159 223 2.9E-15 T 22-04-2016 IPR025605 OST-HTH/LOTUS domain HRM2_RS24025 c53260cd25e61ca11464f6c352707c89 239 PANTHER PTHR35811 5 236 6.4E-52 T 22-04-2016 HRM2_RS24025 c53260cd25e61ca11464f6c352707c89 239 PANTHER PTHR35811:SF1 5 236 6.4E-52 T 22-04-2016 HRM2_RS11935 cc8bb7c7001821f9b64362bcafa656e8 257 Pfam PF14125 Domain of unknown function (DUF4292) 83 229 4.6E-6 T 22-04-2016 IPR025634 Protein of unknown function DUF4292 HRM2_RS11615 4b0f06723670dc9627b1236cef4a8686 1302 PANTHER PTHR38760 676 1235 2.1E-81 T 22-04-2016 HRM2_RS11615 4b0f06723670dc9627b1236cef4a8686 1302 Pfam PF12633 Adenylate cyclase NT domain 684 875 1.0E-46 T 22-04-2016 IPR024685 Adenylate cyclase class-I, N-terminal domain KEGG: 00230+4.6.1.1 HRM2_RS11615 4b0f06723670dc9627b1236cef4a8686 1302 Pfam PF13599 Pentapeptide repeats (9 copies) 546 613 2.8E-9 T 22-04-2016 IPR001646 Pentapeptide repeat HRM2_RS11615 4b0f06723670dc9627b1236cef4a8686 1302 SUPERFAMILY SSF141571 464 626 8.24E-23 T 22-04-2016 HRM2_RS11615 4b0f06723670dc9627b1236cef4a8686 1302 Pfam PF01295 Adenylate cyclase, class-I 903 1236 2.0E-49 T 22-04-2016 IPR000274 Adenylate cyclase, class-I GO:0004016|GO:0006171 KEGG: 00230+4.6.1.1 HRM2_RS04980 1c8d37cafa05990dcbebfacba005514b 162 Pfam PF11322 Protein of unknown function (DUF3124) 35 157 1.1E-50 T 22-04-2016 IPR021471 Protein of unknown function DUF3124 HRM2_RS14925 9571ffdc2cf53b3359bdd7fc7bd7a93b 166 SUPERFAMILY SSF54523 1 65 2.12E-5 T 22-04-2016 HRM2_RS06600 bc21b348ffd7cac1948e5d90b22c20cd 419 TIGRFAM TIGR03790 TIGR03790: TIGR03790 family protein 32 401 7.0E-107 T 22-04-2016 IPR022265 Conserved hypothetical protein CHP03790 HRM2_RS07775 de6e5e8ee1170024e2ca86e57b9eab94 373 Pfam PF12698 ABC-2 family transporter protein 27 364 6.2E-41 T 22-04-2016 HRM2_RS07775 de6e5e8ee1170024e2ca86e57b9eab94 373 PANTHER PTHR30294 1 373 1.9E-86 T 22-04-2016 HRM2_RS07775 de6e5e8ee1170024e2ca86e57b9eab94 373 PANTHER PTHR30294:SF12 1 373 1.9E-86 T 22-04-2016 HRM2_RS00785 3aabe52ae21ae9125848cf20f097d6b5 443 Pfam PF07804 HipA-like C-terminal domain 280 418 8.9E-26 T 22-04-2016 IPR012893 HipA-like, C-terminal HRM2_RS00785 3aabe52ae21ae9125848cf20f097d6b5 443 Pfam PF13657 HipA N-terminal domain 8 122 3.0E-20 T 22-04-2016 IPR017508 HipA, N-terminal subdomain 1 HRM2_RS00785 3aabe52ae21ae9125848cf20f097d6b5 443 Pfam PF07805 HipA-like N-terminal domain 182 274 1.7E-17 T 22-04-2016 IPR012894 HipA, N-terminal subdomain 2 HRM2_RS00785 3aabe52ae21ae9125848cf20f097d6b5 443 PANTHER PTHR37419 168 359 1.0E-12 T 22-04-2016 HRM2_RS00785 3aabe52ae21ae9125848cf20f097d6b5 443 PANTHER PTHR37419:SF2 168 359 1.0E-12 T 22-04-2016 HRM2_RS12770 e6698ddf00eb492cf17754bd6d06b480 304 PANTHER PTHR12001:SF23 3 299 1.2E-114 T 22-04-2016 HRM2_RS12770 e6698ddf00eb492cf17754bd6d06b480 304 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 83 99 - T 22-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 HRM2_RS12770 e6698ddf00eb492cf17754bd6d06b480 304 PANTHER PTHR12001 3 299 1.2E-114 T 22-04-2016 IPR017446 Polyprenyl synthetase-related HRM2_RS12770 e6698ddf00eb492cf17754bd6d06b480 304 SUPERFAMILY SSF48576 7 286 2.7E-87 T 22-04-2016 IPR008949 Isoprenoid synthase domain HRM2_RS12770 e6698ddf00eb492cf17754bd6d06b480 304 Gene3D G3DSA:1.10.600.10 4 299 1.7E-94 T 22-04-2016 IPR008949 Isoprenoid synthase domain HRM2_RS12770 e6698ddf00eb492cf17754bd6d06b480 304 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 222 234 - T 22-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 HRM2_RS12770 e6698ddf00eb492cf17754bd6d06b480 304 Pfam PF00348 Polyprenyl synthetase 34 279 9.5E-61 T 22-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 HRM2_RS14420 e50fecc1d505e6ecabd21ded00b1629b 87 Pfam PF13657 HipA N-terminal domain 34 83 3.6E-5 T 22-04-2016 IPR017508 HipA, N-terminal subdomain 1 HRM2_RS15045 5496179ff1c484dca1b4c66ef52028ea 150 Pfam PF04519 Polymer-forming cytoskeletal 25 120 3.9E-18 T 22-04-2016 IPR007607 Protein of unknown function DUF583 HRM2_RS23085 2a20e6615b554b52142f71fae7a3ec1f 99 PANTHER PTHR33606 1 88 6.6E-14 T 22-04-2016 HRM2_RS23085 2a20e6615b554b52142f71fae7a3ec1f 99 SUPERFAMILY SSF54909 3 89 5.9E-15 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel HRM2_RS23085 2a20e6615b554b52142f71fae7a3ec1f 99 Gene3D G3DSA:3.30.70.1060 1 92 6.7E-23 T 22-04-2016 HRM2_RS23085 2a20e6615b554b52142f71fae7a3ec1f 99 Pfam PF03795 YCII-related domain 1 89 8.3E-10 T 22-04-2016 IPR005545 YCII-related HRM2_RS24980 3909effa8d25b2c1056d1738f32d280e 331 Pfam PF08774 VRR-NUC domain 254 315 4.6E-8 T 22-04-2016 IPR014883 VRR-NUC domain GO:0016788 HRM2_RS24980 3909effa8d25b2c1056d1738f32d280e 331 SMART SM00990 227 327 5.6E-6 T 22-04-2016 IPR014883 VRR-NUC domain GO:0016788 HRM2_RS12695 9eeae7a13f0e7ff6b714192ba363e538 276 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 250 274 3.0E-7 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain HRM2_RS12695 9eeae7a13f0e7ff6b714192ba363e538 276 Pfam PF07589 PEP-CTERM motif 249 272 1.0E-8 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain HRM2_RS18145 d97a2a71966d731a38b68a64400aba17 336 SUPERFAMILY SSF52402 15 165 8.15E-12 T 22-04-2016 HRM2_RS18145 d97a2a71966d731a38b68a64400aba17 336 TIGRFAM TIGR03573 WbuX: N-acetyl sugar amidotransferase 1 322 9.8E-115 T 22-04-2016 IPR020022 N-acetyl sugar amidotransferase HRM2_RS18145 d97a2a71966d731a38b68a64400aba17 336 Gene3D G3DSA:3.40.50.620 59 93 4.1E-4 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HRM2_RS17210 5506b65baab4c99ecc4a737879a722cc 211 Pfam PF07589 PEP-CTERM motif 186 207 6.8E-7 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain HRM2_RS17210 5506b65baab4c99ecc4a737879a722cc 211 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 186 208 3.1E-4 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain HRM2_RS21600 cddc06d1e9d5aa680df2bce79d1508cf 218 Pfam PF04536 Acid phosphatase of thylakoid lumen protein 113 194 8.3E-8 T 22-04-2016 IPR007621 TPM domain HRM2_RS24225 de7823da5ccd28c96d22515f2a7cabf4 360 Gene3D G3DSA:3.40.50.150 176 193 1.3E-12 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS24225 de7823da5ccd28c96d22515f2a7cabf4 360 Gene3D G3DSA:3.40.50.150 253 325 1.3E-12 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS24225 de7823da5ccd28c96d22515f2a7cabf4 360 SUPERFAMILY SSF53335 253 322 5.3E-27 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS24225 de7823da5ccd28c96d22515f2a7cabf4 360 SUPERFAMILY SSF53335 38 193 5.3E-27 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HRM2_RS21605 35d82b55480b9db5c3bd6b5b075c2bb1 321 Pfam PF04536 Acid phosphatase of thylakoid lumen protein 57 178 2.2E-35 T 22-04-2016 IPR007621 TPM domain HRM2_RS21605 35d82b55480b9db5c3bd6b5b075c2bb1 321 PANTHER PTHR30373:SF2 2 321 8.9E-58 T 22-04-2016 HRM2_RS21605 35d82b55480b9db5c3bd6b5b075c2bb1 321 PANTHER PTHR30373 2 321 8.9E-58 T 22-04-2016 HRM2_RS04180 0e30ba2796fb04c9b057c403dae617f5 344 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 34 325 8.5E-84 T 22-04-2016 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 HRM2_RS04180 0e30ba2796fb04c9b057c403dae617f5 344 PIRSF PIRSF006470 5 340 1.5E-91 T 22-04-2016 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 HRM2_RS04180 0e30ba2796fb04c9b057c403dae617f5 344 PANTHER PTHR33376:SF2 1 344 1.6E-78 T 22-04-2016 HRM2_RS04180 0e30ba2796fb04c9b057c403dae617f5 344 PANTHER PTHR33376 1 344 1.6E-78 T 22-04-2016 HRM2_RS04180 0e30ba2796fb04c9b057c403dae617f5 344 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 34 277 7.0E-71 T 22-04-2016 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 HRM2_RS12750 5918be8bd60ba5c4ceb220b4d3f11b80 143 SUPERFAMILY SSF56784 39 135 2.56E-14 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS12750 5918be8bd60ba5c4ceb220b4d3f11b80 143 Gene3D G3DSA:3.40.50.1000 40 130 2.1E-10 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS12285 47e88a44cee9d01fc7d3bda842ada7b2 904 SMART SM00563 380 507 1.2E-24 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 HRM2_RS12285 47e88a44cee9d01fc7d3bda842ada7b2 904 Pfam PF01553 Acyltransferase 373 504 6.8E-19 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 HRM2_RS12285 47e88a44cee9d01fc7d3bda842ada7b2 904 SUPERFAMILY SSF69593 323 567 3.01E-20 T 22-04-2016 HRM2_RS12285 47e88a44cee9d01fc7d3bda842ada7b2 904 PANTHER PTHR12563 286 876 9.1E-126 T 22-04-2016 IPR022284 Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase GO:0008374|GO:0044255 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|UniPathway: UPA00557 HRM2_RS18570 b111e429ac01868890b5794fecae6532 243 SUPERFAMILY SSF46548 29 104 1.15E-15 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HRM2_RS18570 b111e429ac01868890b5794fecae6532 243 Pfam PF13183 4Fe-4S dicluster domain 30 91 2.4E-9 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HRM2_RS18570 b111e429ac01868890b5794fecae6532 243 Gene3D G3DSA:1.10.1060.10 29 107 5.6E-14 T 22-04-2016 HRM2_RS18570 b111e429ac01868890b5794fecae6532 243 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 33 44 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS18570 b111e429ac01868890b5794fecae6532 243 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 77 88 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HRM2_RS17160 52a33ef78b8b49a0809881c119df2f51 171 SUPERFAMILY SSF52218 1 166 2.02E-22 T 22-04-2016 IPR029039 Flavoprotein-like domain HRM2_RS17160 52a33ef78b8b49a0809881c119df2f51 171 Gene3D G3DSA:3.40.50.360 1 169 1.8E-26 T 22-04-2016 IPR029039 Flavoprotein-like domain HRM2_RS17160 52a33ef78b8b49a0809881c119df2f51 171 Pfam PF12641 Flavodoxin domain 4 166 3.9E-15 T 22-04-2016 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 HRM2_RS04325 4067d303e7f0d7d83a431af1443738e0 62 Pfam PF10133 Predicted RNA-binding protein 1 59 6.7E-25 T 22-04-2016 IPR019300 RNA-binding protein, predicted HRM2_RS23470 02ade2e8bc5d9c7bb057ee744c425ca1 355 Pfam PF01594 Domain of unknown function DUF20 20 345 3.5E-61 T 22-04-2016 IPR002549 Transmembrane protein TqsA-like HRM2_RS23470 02ade2e8bc5d9c7bb057ee744c425ca1 355 PANTHER PTHR21716 1 352 3.6E-91 T 22-04-2016 IPR002549 Transmembrane protein TqsA-like HRM2_RS23470 02ade2e8bc5d9c7bb057ee744c425ca1 355 PANTHER PTHR21716:SF19 1 352 3.6E-91 T 22-04-2016 HRM2_RS14450 56efc4343f4de50f8dbe15dfc45af019 386 Pfam PF04285 Protein of unknown function (DUF444) 60 171 5.3E-6 T 22-04-2016 IPR006698 Uncharacterised protein family UPF0229 HRM2_RS14450 56efc4343f4de50f8dbe15dfc45af019 386 Pfam PF04285 Protein of unknown function (DUF444) 185 373 2.2E-27 T 22-04-2016 IPR006698 Uncharacterised protein family UPF0229 HRM2_RS14450 56efc4343f4de50f8dbe15dfc45af019 386 PANTHER PTHR30510 8 386 6.8E-97 T 22-04-2016 HRM2_RS14450 56efc4343f4de50f8dbe15dfc45af019 386 SUPERFAMILY SSF53300 207 348 5.68E-7 T 22-04-2016 IPR002035 von Willebrand factor, type A HRM2_RS08195 1d36837ac2fc062fcbf3592a3485eef9 101 PANTHER PTHR36456 7 96 1.1E-13 T 22-04-2016 HRM2_RS08195 1d36837ac2fc062fcbf3592a3485eef9 101 Pfam PF05258 Protein of unknown function (DUF721) 7 94 1.6E-17 T 22-04-2016 IPR007922 Protein of unknown function DUF721/UPF0232 HRM2_RS16245 bb4f0df2ba87cff36a2ae96e258cbd4a 307 PANTHER PTHR36838 1 307 5.8E-31 T 22-04-2016 HRM2_RS16245 bb4f0df2ba87cff36a2ae96e258cbd4a 307 Pfam PF03547 Membrane transport protein 158 302 3.7E-11 T 22-04-2016 IPR004776 Auxin efflux carrier GO:0016021|GO:0055085 HRM2_RS16245 bb4f0df2ba87cff36a2ae96e258cbd4a 307 Pfam PF03547 Membrane transport protein 3 143 3.5E-11 T 22-04-2016 IPR004776 Auxin efflux carrier GO:0016021|GO:0055085 HRM2_RS03885 271b35b4cd5ee052a98ace9cec49cefb 464 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 2 460 6.4E-109 T 22-04-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 HRM2_RS03885 271b35b4cd5ee052a98ace9cec49cefb 464 PANTHER PTHR30047 1 458 5.1E-106 T 22-04-2016 HRM2_RS25280 a9ad202303a1f7dd0091cc2bb7f08acf 169 SUPERFAMILY SSF53098 44 139 8.34E-7 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS09890 c5acc712c9b61a5071fadb1822ee767d 442 Pfam PF04932 O-Antigen ligase 214 352 1.1E-16 T 22-04-2016 IPR007016 O-antigen ligase-related HRM2_RS05065 fe5a940db6a43f915e1c4837613c60dd 69 PANTHER PTHR30060:SF1 8 68 1.3E-23 T 22-04-2016 HRM2_RS05065 fe5a940db6a43f915e1c4837613c60dd 69 PANTHER PTHR30060 8 68 1.3E-23 T 22-04-2016 HRM2_RS17660 d162ba66b4c226e8e076b1459959cd35 273 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 35 107 5.1E-25 T 22-04-2016 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core HRM2_RS17660 d162ba66b4c226e8e076b1459959cd35 273 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 177 235 9.6E-10 T 22-04-2016 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core HRM2_RS17660 d162ba66b4c226e8e076b1459959cd35 273 SUPERFAMILY SSF101386 11 110 1.96E-26 T 22-04-2016 HRM2_RS17660 d162ba66b4c226e8e076b1459959cd35 273 PANTHER PTHR30522:SF0 16 272 1.6E-96 T 22-04-2016 IPR011551 NTP pyrophosphohydrolase MazG HRM2_RS17660 d162ba66b4c226e8e076b1459959cd35 273 Gene3D G3DSA:1.10.287.1080 143 231 1.1E-10 T 22-04-2016 HRM2_RS17660 d162ba66b4c226e8e076b1459959cd35 273 Gene3D G3DSA:1.10.287.1080 28 81 1.4E-12 T 22-04-2016 HRM2_RS17660 d162ba66b4c226e8e076b1459959cd35 273 TIGRFAM TIGR00444 mazG: MazG family protein 19 266 6.8E-78 T 22-04-2016 IPR011551 NTP pyrophosphohydrolase MazG HRM2_RS17660 d162ba66b4c226e8e076b1459959cd35 273 SUPERFAMILY SSF101386 147 243 3.43E-21 T 22-04-2016 HRM2_RS17660 d162ba66b4c226e8e076b1459959cd35 273 PANTHER PTHR30522 16 272 1.6E-96 T 22-04-2016 HRM2_RS16445 fe5083be2950f051e7b22b24e9e20fe8 293 Pfam PF16811 TRAP transporter T-component 50 293 3.4E-63 T 22-04-2016 IPR031823 TRAP transporter T-component HRM2_RS20670 b54e8fb167da99fd70cbf8758c2ff8cb 142 Pfam PF13211 Protein of unknown function (DUF4019) 33 136 9.8E-36 T 22-04-2016 IPR025091 Protein of unknown function DUF4019 HRM2_RS15775 3f5ac99a17264b324805ddfc74452c0b 216 Pfam PF04250 Protein of unknown function (DUF429) 8 199 1.8E-19 T 22-04-2016 IPR007362 Protein of unknown function DUF429 HRM2_RS16095 6a67e73ee0900d0572dfe0b982d0d759 234 PANTHER PTHR30294 1 232 3.5E-44 T 22-04-2016 HRM2_RS16095 6a67e73ee0900d0572dfe0b982d0d759 234 Pfam PF12679 ABC-2 family transporter protein 57 187 3.8E-8 T 22-04-2016 IPR032688 ABC-2 family transporter protein GO:0006810 HRM2_RS16095 6a67e73ee0900d0572dfe0b982d0d759 234 PANTHER PTHR30294:SF5 1 232 3.5E-44 T 22-04-2016 HRM2_RS00890 c97b91ccb1e9b7fdf465ffae06e425b0 229 Pfam PF02517 CAAX protease self-immunity 134 219 1.2E-8 T 22-04-2016 IPR003675 CAAX amino terminal protease GO:0016020 HRM2_RS04590 a97f17cff8d558c99c0041c25e20333f 86 Pfam PF13711 Domain of unknown function (DUF4160) 9 71 1.7E-19 T 22-04-2016 IPR025427 Protein of unknown function DUF4160 HRM2_RS03105 10eb51e0100d7e94e2069d91e1b60028 261 Pfam PF12787 EcsC protein family 6 243 9.2E-38 T 22-04-2016 IPR024787 EcsC protein HRM2_RS02545 f9d7b0cad95c4e8549042038167447de 141 PIRSF PIRSF032131 1 139 3.5E-34 T 22-04-2016 IPR009562 Protein of unknown function DUF1178 HRM2_RS02545 f9d7b0cad95c4e8549042038167447de 141 Pfam PF06676 Protein of unknown function (DUF1178) 1 134 3.4E-41 T 22-04-2016 IPR009562 Protein of unknown function DUF1178 HRM2_RS23225 5ac511513d41f9a4864489483d6c2e7d 214 Pfam PF01184 GPR1/FUN34/yaaH family 5 185 2.4E-6 T 22-04-2016 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 HRM2_RS20990 cf3327ce270e9a441fb59a53352f3696 156 SUPERFAMILY SSF56784 15 117 8.53E-10 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS20990 cf3327ce270e9a441fb59a53352f3696 156 Gene3D G3DSA:3.40.50.1000 16 135 6.4E-7 T 22-04-2016 IPR023214 HAD-like domain HRM2_RS08740 0bc7253ce995c828cdcfb19f4d3a96ca 233 Pfam PF04012 PspA/IM30 family 3 211 2.9E-38 T 22-04-2016 IPR007157 PspA/IM30 HRM2_RS08740 0bc7253ce995c828cdcfb19f4d3a96ca 233 PANTHER PTHR31088 2 233 1.1E-33 T 22-04-2016 HRM2_RS19370 3d959826e2bed1813b59115246055567 193 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 167 190 4.5E-4 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain HRM2_RS19370 3d959826e2bed1813b59115246055567 193 Pfam PF07589 PEP-CTERM motif 166 189 2.7E-4 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain HRM2_RS09850 0f9000ece426bdee3f1708d9ff869c25 353 Pfam PF01757 Acyltransferase family 7 324 3.1E-17 T 22-04-2016 IPR002656 Acyltransferase 3 GO:0016747 HRM2_RS18655 7abffd3750322a9a5569b1d9d21b2059 354 SUPERFAMILY SSF51726 103 352 5.62E-22 T 22-04-2016 HRM2_RS20545 4386304f73f4994d03ee189129a05dd4 262 Gene3D G3DSA:3.20.20.370 45 258 6.9E-10 T 22-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 HRM2_RS20545 4386304f73f4994d03ee189129a05dd4 262 SUPERFAMILY SSF88713 35 215 4.45E-13 T 22-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 HRM2_RS20545 4386304f73f4994d03ee189129a05dd4 262 Pfam PF01522 Polysaccharide deacetylase 35 166 1.7E-5 T 22-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 HRM2_RS22910 27228196e3f60b3a5d032ddf9823a08c 562 Gene3D G3DSA:3.30.420.10 153 298 3.5E-5 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS01925 71e438e1fd4e1f7900ab9a8046b52245 82 Pfam PF04226 Transglycosylase associated protein 34 82 2.4E-11 T 22-04-2016 IPR007341 Transglycosylase-associated protein GO:0016021 HRM2_RS01925 71e438e1fd4e1f7900ab9a8046b52245 82 PANTHER PTHR33884:SF1 1 81 3.0E-23 T 22-04-2016 HRM2_RS01925 71e438e1fd4e1f7900ab9a8046b52245 82 PANTHER PTHR33884 1 81 3.0E-23 T 22-04-2016 HRM2_RS16625 b57afeca29724b60d255e8e62a4c89b3 576 Pfam PF16949 Putative ATP-binding cassette 40 571 5.9E-96 T 22-04-2016 IPR031599 Putative ATP-binding cassette HRM2_RS14060 b8fc25edaf29a12b6e2696bfc1ee85cf 234 Pfam PF10056 Uncharacterized conserved protein (DUF2293) 122 207 5.5E-19 T 22-04-2016 IPR018744 Domain of unknown function DUF2293 HRM2_RS17665 ea59ca434d5fa26ac6f49a58bc4047a8 182 PANTHER PTHR36926:SF1 1 153 5.3E-21 T 22-04-2016 HRM2_RS17665 ea59ca434d5fa26ac6f49a58bc4047a8 182 PANTHER PTHR36926 1 153 5.3E-21 T 22-04-2016 HRM2_RS17665 ea59ca434d5fa26ac6f49a58bc4047a8 182 Pfam PF02674 Colicin V production protein 4 144 9.6E-36 T 22-04-2016 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 HRM2_RS05600 8d871595fc9fff63d4303b5a4ee79ecc 177 Pfam PF04612 Type II secretion system (T2SS), protein M 3 156 1.7E-6 T 22-04-2016 IPR007690 Type II secretion system, protein M GO:0006858 HRM2_RS05600 8d871595fc9fff63d4303b5a4ee79ecc 177 Gene3D G3DSA:3.30.70.60 81 160 1.3E-4 T 22-04-2016 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 HRM2_RS17390 cb755eab5b39b6961cb5f386af7efb3a 141 Pfam PF00430 ATP synthase B/B' CF(0) 8 137 7.3E-12 T 22-04-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 HRM2_RS09070 5df72cd028d1d4038ae68bfd3bd83928 355 SUPERFAMILY SSF53756 128 351 1.15E-8 T 22-04-2016 HRM2_RS09070 5df72cd028d1d4038ae68bfd3bd83928 355 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 128 351 6.7E-11 T 22-04-2016 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 HRM2_RS22645 c3b8c4f7a952fcd749554f6dcd84b695 422 Pfam PF05036 Sporulation related domain 346 418 4.9E-12 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 HRM2_RS22645 c3b8c4f7a952fcd749554f6dcd84b695 422 Gene3D G3DSA:3.30.70.1070 342 416 1.0E-9 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 HRM2_RS22645 c3b8c4f7a952fcd749554f6dcd84b695 422 SUPERFAMILY SSF110997 343 412 4.58E-10 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 HRM2_RS14680 f71e34ba2b0dec4cebae964ce181b884 242 Pfam PF10816 Domain of unknown function (DUF2760) 121 240 2.9E-50 T 22-04-2016 IPR021212 Domain of unknown function DUF2760 HRM2_RS13585 97d123f925eb3d9931cabbd426091a50 1200 Gene3D G3DSA:3.30.1330.60 1020 1062 9.6E-6 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS13585 97d123f925eb3d9931cabbd426091a50 1200 Gene3D G3DSA:3.30.1330.60 1146 1177 9.6E-6 T 22-04-2016 IPR006665 OmpA-like domain HRM2_RS13585 97d123f925eb3d9931cabbd426091a50 1200 Pfam PF05359 Domain of Unknown Function (DUF748) 589 740 3.3E-22 T 22-04-2016 IPR008023 Protein of unknown function DUF748 HRM2_RS13585 97d123f925eb3d9931cabbd426091a50 1200 Pfam PF05359 Domain of Unknown Function (DUF748) 807 952 4.0E-32 T 22-04-2016 IPR008023 Protein of unknown function DUF748 HRM2_RS13585 97d123f925eb3d9931cabbd426091a50 1200 Pfam PF05359 Domain of Unknown Function (DUF748) 149 301 9.5E-13 T 22-04-2016 IPR008023 Protein of unknown function DUF748 HRM2_RS13585 97d123f925eb3d9931cabbd426091a50 1200 Pfam PF05359 Domain of Unknown Function (DUF748) 369 515 1.5E-15 T 22-04-2016 IPR008023 Protein of unknown function DUF748 HRM2_RS03620 1277440f9bb3d5f8807b1f1c96b8c3ba 191 Pfam PF03692 Putative zinc- or iron-chelating domain 28 108 6.9E-8 T 22-04-2016 IPR005358 Putative zinc- or iron-chelating domain containing protein HRM2_RS05095 97b2e97a17b22d6248360465a2af8bea 353 Pfam PF02253 Phospholipase A1 85 349 1.1E-103 T 22-04-2016 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 HRM2_RS05095 97b2e97a17b22d6248360465a2af8bea 353 PRINTS PR01486 Bacterial phospholipase A1 protein signature 132 149 8.7E-29 T 22-04-2016 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 HRM2_RS05095 97b2e97a17b22d6248360465a2af8bea 353 PRINTS PR01486 Bacterial phospholipase A1 protein signature 322 342 8.7E-29 T 22-04-2016 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 HRM2_RS05095 97b2e97a17b22d6248360465a2af8bea 353 PRINTS PR01486 Bacterial phospholipase A1 protein signature 265 283 8.7E-29 T 22-04-2016 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 HRM2_RS05095 97b2e97a17b22d6248360465a2af8bea 353 PRINTS PR01486 Bacterial phospholipase A1 protein signature 178 197 8.7E-29 T 22-04-2016 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 HRM2_RS05095 97b2e97a17b22d6248360465a2af8bea 353 PRINTS PR01486 Bacterial phospholipase A1 protein signature 300 317 8.7E-29 T 22-04-2016 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 HRM2_RS05095 97b2e97a17b22d6248360465a2af8bea 353 SUPERFAMILY SSF56931 87 352 7.19E-87 T 22-04-2016 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 HRM2_RS05095 97b2e97a17b22d6248360465a2af8bea 353 Gene3D G3DSA:2.40.230.10 85 352 1.1E-94 T 22-04-2016 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 HRM2_RS05095 97b2e97a17b22d6248360465a2af8bea 353 PANTHER PTHR40457 77 353 8.9E-86 T 22-04-2016 HRM2_RS11395 df10b0bb205a050b5d8e54137f214a02 180 Pfam PF09831 Uncharacterized protein conserved in bacteria (DUF2058) 4 172 2.5E-38 T 22-04-2016 IPR018636 Protein of unknown function DUF2058 HRM2_RS06365 17b19e9ec5d64b3109b9bc17b2196167 222 PANTHER PTHR12677 6 220 2.1E-40 T 22-04-2016 IPR015414 Transmembrane protein TMEM64/TMEM41 GO:0016021 HRM2_RS06365 17b19e9ec5d64b3109b9bc17b2196167 222 Pfam PF09335 SNARE associated Golgi protein 67 183 1.1E-21 T 22-04-2016 IPR032816 SNARE associated Golgi protein HRM2_RS10475 7682108609b0813937c3652eb962e461 269 Pfam PF09359 VTC domain 15 251 5.6E-32 T 22-04-2016 IPR018966 VTC domain HRM2_RS25560 9b5bd4aba72841e370ab0effcd213966 242 SUPERFAMILY SSF48695 135 239 3.63E-12 T 22-04-2016 IPR011031 Multihaem cytochrome HRM2_RS25560 9b5bd4aba72841e370ab0effcd213966 242 Gene3D G3DSA:3.90.10.10 185 240 5.8E-5 T 22-04-2016 HRM2_RS25560 9b5bd4aba72841e370ab0effcd213966 242 Pfam PF02085 Class III cytochrome C family 134 239 2.5E-13 T 22-04-2016 IPR020942 Class III cytochrome C GO:0009055|GO:0020037 HRM2_RS25560 9b5bd4aba72841e370ab0effcd213966 242 Gene3D G3DSA:3.90.10.10 134 184 6.5E-9 T 22-04-2016 HRM2_RS23285 f898abbbcb842c7ed2cd411d92ccadd6 836 SUPERFAMILY SSF48371 86 202 1.02E-5 T 22-04-2016 IPR016024 Armadillo-type fold GO:0005488 HRM2_RS23285 f898abbbcb842c7ed2cd411d92ccadd6 836 SUPERFAMILY SSF48371 385 446 1.02E-5 T 22-04-2016 IPR016024 Armadillo-type fold GO:0005488 HRM2_RS23285 f898abbbcb842c7ed2cd411d92ccadd6 836 Gene3D G3DSA:1.25.10.10 69 198 6.3E-5 T 22-04-2016 IPR011989 Armadillo-like helical HRM2_RS10525 6757a5857b490e644929e849bf7390ca 249 Pfam PF11141 Protein of unknown function (DUF2914) 187 247 1.0E-18 T 22-04-2016 IPR022606 Protein of unknown function DUF2914 HRM2_RS11505 6d528740af0d27d09652f70bc28053c9 66 Pfam PF13617 YnbE-like lipoprotein 8 56 3.9E-6 T 22-04-2016 IPR025985 YnbE-like lipoprotein HRM2_RS22295 7b7e1f2e513007671a0a06ec61a3a3d9 180 Pfam PF13689 Domain of unknown function (DUF4154) 30 172 1.2E-44 T 22-04-2016 IPR025293 Protein of unknown function DUF4154 HRM2_RS22055 a9b84015c10c7bb6f0ea5e8edf3b3c3c 661 Pfam PF04471 Restriction endonuclease 64 159 2.4E-6 T 22-04-2016 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 HRM2_RS25045 78a76a5e964b22501848134f245b51a4 181 Gene3D G3DSA:1.25.40.10 82 178 3.5E-10 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS25045 78a76a5e964b22501848134f245b51a4 181 SUPERFAMILY SSF48452 78 176 4.03E-10 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HRM2_RS14405 496c79a4cf9f5cce5fcf4a26565d7277 339 Pfam PF08902 Domain of unknown function (DUF1848) 24 316 1.1E-97 T 22-04-2016 IPR014998 Protein of unknown function DUF1848 HRM2_RS12110 f621dc170b4de5ddf5b349ea8e15667f 107 SUPERFAMILY SSF52218 13 100 8.38E-7 T 22-04-2016 IPR029039 Flavoprotein-like domain HRM2_RS12110 f621dc170b4de5ddf5b349ea8e15667f 107 Gene3D G3DSA:3.40.50.360 15 105 6.0E-10 T 22-04-2016 IPR029039 Flavoprotein-like domain HRM2_RS00885 54227864f5d161a6c86c4ab9b4d052b0 530 Gene3D G3DSA:2.40.50.140 20 89 2.0E-4 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold HRM2_RS00885 54227864f5d161a6c86c4ab9b4d052b0 530 SUPERFAMILY SSF64182 140 526 6.8E-28 T 22-04-2016 HRM2_RS09085 0bb95e22210c4bb482e45dbe78abfc85 412 Pfam PF04932 O-Antigen ligase 184 340 7.1E-10 T 22-04-2016 IPR007016 O-antigen ligase-related HRM2_RS24990 be1c3c59aed665743b0e0b448cd6b587 296 Pfam PF08478 POTRA domain, FtsQ-type 63 131 3.3E-15 T 22-04-2016 IPR013685 Polypeptide-transport-associated, FtsQ-type HRM2_RS24990 be1c3c59aed665743b0e0b448cd6b587 296 PANTHER PTHR35851:SF1 32 173 1.0E-16 T 22-04-2016 HRM2_RS24990 be1c3c59aed665743b0e0b448cd6b587 296 PANTHER PTHR35851 32 173 1.0E-16 T 22-04-2016 HRM2_RS12965 619938cce82a9006e09aa0563079816f 222 SUPERFAMILY SSF52540 5 214 3.71E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12965 619938cce82a9006e09aa0563079816f 222 Gene3D G3DSA:3.40.50.300 12 150 1.8E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19690 619938cce82a9006e09aa0563079816f 222 SUPERFAMILY SSF52540 5 214 3.71E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS19690 619938cce82a9006e09aa0563079816f 222 Gene3D G3DSA:3.40.50.300 12 150 1.8E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HRM2_RS12125 ddadaa5efa181147ab350e79a84be450 62 SUPERFAMILY SSF56935 2 55 7.32E-5 T 22-04-2016 HRM2_RS12125 ddadaa5efa181147ab350e79a84be450 62 Gene3D G3DSA:2.170.130.10 2 51 1.3E-4 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 HRM2_RS07535 31ecd6d27660a7ff0aea94f5de94781c 171 Pfam PF11821 Protein of unknown function (DUF3341) 8 163 1.0E-42 T 22-04-2016 IPR021776 Protein of unknown function DUF3341 HRM2_RS09035 8636aab163b9dc372a2b6f6735e31ca6 364 PANTHER PTHR30606 57 360 8.4E-57 T 22-04-2016 HRM2_RS09035 8636aab163b9dc372a2b6f6735e31ca6 364 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 80 358 6.2E-49 T 22-04-2016 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 HRM2_RS12105 ba1f1af0943ed9453e02a2ce08551ba3 187 Pfam PF07796 Protein of unknown function (DUF1638) 31 180 1.4E-20 T 22-04-2016 IPR012437 Domain of unknown function DUF1638 HRM2_RS15900 8190bb331ea146f91975b5b6f536b52a 278 Pfam PF00561 alpha/beta hydrolase fold 57 154 3.6E-12 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HRM2_RS15900 8190bb331ea146f91975b5b6f536b52a 278 Gene3D G3DSA:3.40.50.1820 38 275 2.6E-50 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS15900 8190bb331ea146f91975b5b6f536b52a 278 SUPERFAMILY SSF53474 35 275 7.88E-52 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold HRM2_RS15900 8190bb331ea146f91975b5b6f536b52a 278 PANTHER PTHR10992 37 277 1.8E-45 T 22-04-2016 HRM2_RS08165 3d2e75862fe3025ea99e828768a5df23 143 Pfam PF03692 Putative zinc- or iron-chelating domain 13 111 6.7E-12 T 22-04-2016 IPR005358 Putative zinc- or iron-chelating domain containing protein HRM2_RS06645 00f4c2da2fc0dc76a2d0357b14f597ec 98 TIGRFAM TIGR02230 ATPase_gene1: putative F0F1-ATPase subunit 10 96 1.4E-24 T 22-04-2016 IPR011744 F0F1-ATPase subunit, putative HRM2_RS06645 00f4c2da2fc0dc76a2d0357b14f597ec 98 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 39 92 1.1E-10 T 22-04-2016 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter HRM2_RS05830 77c01dc5163369264a76f261371a6cfd 79 Gene3D G3DSA:1.10.720.30 14 71 7.7E-32 T 22-04-2016 IPR003034 SAP domain HRM2_RS05830 77c01dc5163369264a76f261371a6cfd 79 Pfam PF09905 Uncharacterized conserved protein (DUF2132) 7 68 1.5E-34 T 22-04-2016 IPR018668 DNA-binding protein VF530-like, bacteria GO:0003677 HRM2_RS18800 64c8d4b53fb585536e6d68dd88c0e47d 408 Pfam PF01566 Natural resistance-associated macrophage protein 39 381 1.6E-55 T 22-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 HRM2_RS12865 1c794f4fc8579ece65e67b61ef1e5793 1263 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 913 1262 2.5E-41 T 22-04-2016 IPR007452 Translocation and assembly module TamB HRM2_RS09420 8e37ee8c1261ee820cabcf8f86ec304f 216 ProDom PD032436 LIPOPROTEIN UNCHARACTERIZED PROBABLE CJ0457C SIMILAR TRANSFERASE BACTERIA PRECURSOR SIGNAL CC0304 17 133 4.0E-8 T 22-04-2016 IPR007172 Domain of unknown function DUF374 HRM2_RS09420 8e37ee8c1261ee820cabcf8f86ec304f 216 Pfam PF04028 Domain of unknown function (DUF374) 68 133 2.9E-18 T 22-04-2016 IPR007172 Domain of unknown function DUF374 HRM2_RS20740 1c2a8f144246bb7b9c16c23383f57c24 299 Pfam PF09712 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) 76 289 7.8E-22 T 22-04-2016 IPR010123 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaE subunit HRM2_RS21745 81cff7da48d161e1b9b073b793a73360 485 Pfam PF06253 Trimethylamine methyltransferase (MTTB) 6 471 6.2E-86 T 22-04-2016 IPR010426 Trimethylamine methyltransferase GO:0008168|GO:0015948 KEGG: 00680+2.1.1.250|MetaCyc: PWY-5250|UniPathway: UPA00645 HRM2_RS02445 3ec8a9337f23392c36d27c90c689cd2b 300 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 284 1.6E-40 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 HRM2_RS02445 3ec8a9337f23392c36d27c90c689cd2b 300 PANTHER PTHR11795 1 300 9.4E-105 T 22-04-2016 HRM2_RS02445 3ec8a9337f23392c36d27c90c689cd2b 300 PANTHER PTHR11795:SF371 1 300 9.4E-105 T 22-04-2016 HRM2_RS16230 f615366c63c03a5d35217a81752f76b0 121 Pfam PF11141 Protein of unknown function (DUF2914) 60 119 4.4E-17 T 22-04-2016 IPR022606 Protein of unknown function DUF2914 HRM2_RS12155 6613b6dd113a60df02e13c9aab974635 278 Pfam PF02405 Permease MlaE 63 274 8.9E-46 T 22-04-2016 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 HRM2_RS12155 6613b6dd113a60df02e13c9aab974635 278 PANTHER PTHR30188 12 277 1.8E-28 T 22-04-2016 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 HRM2_RS09705 ecdb68228238fc6753d3f32ff94468b2 284 Pfam PF07589 PEP-CTERM motif 258 280 1.2E-7 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain HRM2_RS09705 ecdb68228238fc6753d3f32ff94468b2 284 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 258 282 0.0013 T 22-04-2016 IPR013424 PEP-CTERM protein-sorting domain HRM2_RS14900 822d6145b50c718ac34d00bc668a52c9 214 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 29 7.2E-4 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site HRM2_RS15955 6f994d36c1cecd8169d1acbc359829db 119 ProDom PD050957 AF2391 PREDICTED 1 25 0.008 T 22-04-2016 HRM2_RS06185 406c9eac122b27e841e5605d648d76d8 303 Pfam PF01619 Proline dehydrogenase 37 293 5.6E-32 T 22-04-2016 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|UniPathway: UPA00261 HRM2_RS06185 406c9eac122b27e841e5605d648d76d8 303 SUPERFAMILY SSF51730 28 298 2.47E-63 T 22-04-2016 IPR029041 FAD-linked oxidoreductase-like HRM2_RS06185 406c9eac122b27e841e5605d648d76d8 303 PIRSF PIRSF000196 5 303 1.8E-93 T 22-04-2016 IPR008219 Proline dehydrogenase GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|UniPathway: UPA00261 HRM2_RS06185 406c9eac122b27e841e5605d648d76d8 303 Gene3D G3DSA:3.20.20.220 27 296 3.1E-58 T 22-04-2016 IPR029041 FAD-linked oxidoreductase-like HRM2_RS02040 d8a79b4bdde1298bdd1b49c7e6eaa27e 92 Pfam PF09084 NMT1/THI5 like 20 90 4.3E-10 T 22-04-2016 IPR015168 SsuA/THI5-like HRM2_RS03415 b76b6dc9984417534f778a36ccaa653c 151 Pfam PF09719 Putative redox-active protein (C_GCAxxG_C_C) 16 136 1.8E-19 T 22-04-2016 IPR010181 CGCAxxGCC motif HRM2_RS25155 c95832b7c2db6cb4be969053bb1ccf7a 140 Pfam PF04892 VanZ like family 38 121 4.3E-14 T 22-04-2016 IPR006976 VanZ-like HRM2_RS05710 8b32925ce7edab0064be3f724a30328d 441 Gene3D G3DSA:3.20.20.70 203 389 1.4E-15 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HRM2_RS05710 8b32925ce7edab0064be3f724a30328d 441 Pfam PF04055 Radical SAM superfamily 203 366 4.1E-10 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HRM2_RS05710 8b32925ce7edab0064be3f724a30328d 441 SUPERFAMILY SSF102114 203 401 2.16E-18 T 22-04-2016 HRM2_RS13155 30b28e7e391438a1a87a7b5b60e3735e 307 Gene3D G3DSA:3.40.190.10 113 189 4.0E-5 T 22-04-2016 HRM2_RS13155 30b28e7e391438a1a87a7b5b60e3735e 307 SUPERFAMILY SSF53850 54 291 1.03E-18 T 22-04-2016 HRM2_RS04365 4d29568500e542808980609a7bdf3b6d 303 Pfam PF01145 SPFH domain / Band 7 family 47 232 7.9E-15 T 22-04-2016 IPR001107 Band 7 domain HRM2_RS04365 4d29568500e542808980609a7bdf3b6d 303 SUPERFAMILY SSF117892 98 219 6.15E-11 T 22-04-2016 IPR001107 Band 7 domain HRM2_RS22050 294a1502360b655748b53035a8d469cf 616 Pfam PF13910 Domain of unknown function (DUF4209) 506 595 2.3E-12 T 22-04-2016 IPR025209 Domain of unknown function DUF4209 HRM2_RS06240 80afa52f7a330c8b6503b47edc57d026 115 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 13 107 4.2E-22 T 22-04-2016 IPR008407 Branched-chain amino acid transport, AzlD HRM2_RS20630 9dec5c8035cad50509ede9346b44615b 165 Pfam PF13801 Heavy-metal resistance 10 122 1.8E-21 T 22-04-2016 IPR025961 Heavy-metal resistance protein HRM2_RS11740 903c3d1f0b5fe7cf899a44eca0715926 147 Pfam PF07238 PilZ domain 23 124 6.8E-9 T 22-04-2016 IPR009875 PilZ domain GO:0035438 HRM2_RS11740 903c3d1f0b5fe7cf899a44eca0715926 147 Gene3D G3DSA:2.40.10.220 25 131 3.7E-6 T 22-04-2016 HRM2_RS21215 aa3aafa2cb5e002ddd2b46a581c35a8c 370 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 33 369 2.9E-59 T 22-04-2016 IPR010327 FldB/FldC dehydratase alpha/beta subunit HRM2_RS21215 aa3aafa2cb5e002ddd2b46a581c35a8c 370 PANTHER PTHR30548 2 370 5.0E-57 T 22-04-2016 HRM2_RS19285 8ee4070e47030474f2eebc3ab6c85604 68 SUPERFAMILY SSF140683 1 65 1.83E-6 T 22-04-2016 HRM2_RS22220 e60c45889a5b0ff44c6b7dd8af3dd01b 277 Pfam PF14358 Domain of unknown function (DUF4405) 6 72 5.2E-15 T 22-04-2016 IPR025517 Domain of unknown function DUF4405 HRM2_RS25265 b804265972eb59bc9baeb7a6eb6ed935 125 Pfam PF13701 Transposase DDE domain group 1 22 117 3.5E-8 T 22-04-2016 IPR025668 Transposase DDE domain HRM2_RS25320 e5466d8c08f714ad0418235aa354d492 191 Pfam PF14341 PilX N-terminal 8 56 1.1E-14 T 22-04-2016 IPR025746 Type 4 fimbrial biogenesis protein PilX, N-terminal domain HRM2_RS25700 f8462954325b774a7ccb25266f4b9933 210 SUPERFAMILY SSF159594 46 204 7.59E-17 T 22-04-2016 HRM2_RS25700 f8462954325b774a7ccb25266f4b9933 210 Gene3D G3DSA:3.40.50.10610 44 204 4.2E-10 T 22-04-2016 IPR005586 ABC-type transport auxiliary lipoprotein component HRM2_RS15530 bdd643238c2bcd033457b87a5de9c098 484 SUPERFAMILY SSF56935 382 459 5.95E-10 T 22-04-2016 HRM2_RS15530 bdd643238c2bcd033457b87a5de9c098 484 SUPERFAMILY SSF56935 298 332 5.95E-10 T 22-04-2016 HRM2_RS15530 bdd643238c2bcd033457b87a5de9c098 484 SUPERFAMILY SSF56935 24 222 5.95E-10 T 22-04-2016 HRM2_RS07595 18ad180788a847d3686ec364468fbf7c 472 SUPERFAMILY SSF56935 36 311 3.44E-7 T 22-04-2016 HRM2_RS11910 faa166741b9d9ca3e541cefcb49b3337 63 Pfam PF10133 Predicted RNA-binding protein 1 60 8.0E-22 T 22-04-2016 IPR019300 RNA-binding protein, predicted HRM2_RS21440 4e75b109455c8e7cc9777020038abdca 379 Gene3D G3DSA:3.20.20.210 118 367 4.7E-11 T 22-04-2016 HRM2_RS21440 4e75b109455c8e7cc9777020038abdca 379 SUPERFAMILY SSF51726 198 366 2.44E-10 T 22-04-2016 HRM2_RS16090 e3ebebd7c9609e6cb47ef4bcd55f71bb 743 Pfam PF09822 ABC-type uncharacterized transport system 31 180 2.2E-44 T 22-04-2016 IPR019196 ABC-type uncharacterised transport system HRM2_RS16090 e3ebebd7c9609e6cb47ef4bcd55f71bb 743 Pfam PF09822 ABC-type uncharacterized transport system 183 463 9.3E-36 T 22-04-2016 IPR019196 ABC-type uncharacterised transport system HRM2_RS25500 b074a446621b82e6cd19d9fd2c1b3a76 258 PANTHER PTHR22936:SF27 112 250 4.6E-24 T 22-04-2016 HRM2_RS25500 b074a446621b82e6cd19d9fd2c1b3a76 258 Gene3D G3DSA:1.20.1540.10 79 251 6.9E-21 T 22-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 HRM2_RS25500 b074a446621b82e6cd19d9fd2c1b3a76 258 PANTHER PTHR22936 112 250 4.6E-24 T 22-04-2016 IPR002610 Peptidase S54, rhomboid GO:0004252|GO:0006508|GO:0016021 HRM2_RS25500 b074a446621b82e6cd19d9fd2c1b3a76 258 Pfam PF01694 Rhomboid family 113 253 1.5E-19 T 22-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 HRM2_RS25500 b074a446621b82e6cd19d9fd2c1b3a76 258 SUPERFAMILY SSF144091 79 252 7.46E-25 T 22-04-2016 HRM2_RS01840 b75eb37e0f6dee7b1e2a81ebe59c441e 343 Pfam PF12698 ABC-2 family transporter protein 22 334 1.4E-29 T 22-04-2016 HRM2_RS05970 d5d4c2999540cf9be261b493fb9af281 148 Gene3D G3DSA:1.10.10.10 81 135 4.4E-5 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HRM2_RS10470 eb318c9df169a24715230f8464abc8ad 228 Pfam PF16316 Domain of unknown function (DUF4956) 35 169 3.7E-11 T 22-04-2016 IPR032531 Protein of unknown function DUF4956 HRM2_RS24870 c1ca8ac12d0d46e19d6aa72a7f9a2551 543 Pfam PF07603 Protein of unknown function (DUF1566) 380 458 6.4E-15 T 22-04-2016 IPR011460 Protein of unknown function DUF1566 HRM2_RS24870 c1ca8ac12d0d46e19d6aa72a7f9a2551 543 Pfam PF07603 Protein of unknown function (DUF1566) 154 276 3.9E-25 T 22-04-2016 IPR011460 Protein of unknown function DUF1566 HRM2_RS10175 812e6916b2e8cecc85e8c55f8c7cc908 321 SUPERFAMILY SSF55729 27 183 2.12E-7 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase HRM2_RS02970 a5980f8055a831d5ab1b2bd85423be85 130 Pfam PF09656 Putative transmembrane protein (PGPGW) 57 88 1.5E-8 T 22-04-2016 IPR019099 Uncharacterised protein family PGPGW, transmembrane HRM2_RS24940 f69a56499f7332c9950511a83a1d5be9 234 Pfam PF03692 Putative zinc- or iron-chelating domain 61 149 1.1E-6 T 22-04-2016 IPR005358 Putative zinc- or iron-chelating domain containing protein HRM2_RS07590 34d99b54bddeeba547a2fb41c767edda 589 SUPERFAMILY SSF69318 255 333 3.01E-7 T 22-04-2016 HRM2_RS08025 94d75d69fda3c27ba26c260b5ce6ffba 426 Pfam PF09861 Domain of unknown function (DUF2088) 66 191 1.0E-5 T 22-04-2016 IPR018657 Domain of unknown function DUF2088 HRM2_RS01115 182ac53e2cba6216720598bcf9897ff2 351 PANTHER PTHR38139:SF1 33 351 2.7E-38 T 22-04-2016 HRM2_RS01115 182ac53e2cba6216720598bcf9897ff2 351 PANTHER PTHR38139 33 351 2.7E-38 T 22-04-2016 HRM2_RS10075 7d40d7fd842a99a9512e11d1ea5eb12d 424 Pfam PF04015 Domain of unknown function (DUF362) 66 203 2.9E-5 T 22-04-2016 IPR007160 Domain of unknown function DUF362 HRM2_RS14950 178a0b15091d67f1ef184d68967d8e20 289 Pfam PF03994 Domain of Unknown Function (DUF350) 155 204 1.4E-10 T 22-04-2016 IPR007140 Protein of unknown function DUF350 HRM2_RS14950 178a0b15091d67f1ef184d68967d8e20 289 Pfam PF03994 Domain of Unknown Function (DUF350) 84 139 3.0E-5 T 22-04-2016 IPR007140 Protein of unknown function DUF350 HRM2_RS18355 458d2168b64618ddb478cebf856aa4a0 166 Pfam PF03748 Flagellar basal body-associated protein FliL 80 166 6.5E-11 T 22-04-2016 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 HRM2_RS09910 1db4108594548b59599aba35aa4f2341 96 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 3 88 9.1E-9 T 22-04-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family HRM2_RS21520 36d04ef7cdf91525af1a4c2a3041a894 1180 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 638 703 7.6E-4 T 22-04-2016 IPR010221 VCBS repeat HRM2_RS04330 9b443df0353211528c001291f8ad72ce 151 Pfam PF12953 Domain of unknown function (DUF3842) 8 135 2.6E-53 T 22-04-2016 IPR024208 Protein of unknown function DUF3842 HRM2_RS20485 5d251affa957a4a6fa0e8c7b601e8b2c 320 Pfam PF08885 GSCFA family 47 310 7.9E-50 T 22-04-2016 IPR014982 GSCFA HRM2_RS23685 2c1e049ca2f4e54a2a6eb90faed6e921 2194 TIGRFAM TIGR04534 ELWxxDGT_rpt: ELWxxDGT repeat 1779 1811 3.5E-11 T 22-04-2016 IPR030916 ELWxxDGT repeat HRM2_RS23685 2c1e049ca2f4e54a2a6eb90faed6e921 2194 TIGRFAM TIGR04534 ELWxxDGT_rpt: ELWxxDGT repeat 1888 1913 8.2E-7 T 22-04-2016 IPR030916 ELWxxDGT repeat HRM2_RS23685 2c1e049ca2f4e54a2a6eb90faed6e921 2194 TIGRFAM TIGR04534 ELWxxDGT_rpt: ELWxxDGT repeat 1935 1961 2.3E-5 T 22-04-2016 IPR030916 ELWxxDGT repeat HRM2_RS23685 2c1e049ca2f4e54a2a6eb90faed6e921 2194 TIGRFAM TIGR04534 ELWxxDGT_rpt: ELWxxDGT repeat 1981 2024 8.7E-9 T 22-04-2016 IPR030916 ELWxxDGT repeat HRM2_RS23820 93238e3f90e352cea2c0ee411e63b657 448 PANTHER PTHR38075 1 448 6.7E-46 T 22-04-2016 HRM2_RS23820 93238e3f90e352cea2c0ee411e63b657 448 Pfam PF13598 Domain of unknown function (DUF4139) 309 446 6.8E-8 T 22-04-2016 IPR011935 Conserved hypothetical protein CHP02231 HRM2_RS01555 dc5b552e2d5a95596e10c58903462d62 200 PANTHER PTHR35011:SF2 3 40 1.2E-20 T 22-04-2016 HRM2_RS01555 dc5b552e2d5a95596e10c58903462d62 200 PANTHER PTHR35011:SF2 59 195 1.2E-20 T 22-04-2016 HRM2_RS01555 dc5b552e2d5a95596e10c58903462d62 200 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 26 168 1.1E-18 T 22-04-2016 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component HRM2_RS01555 dc5b552e2d5a95596e10c58903462d62 200 PANTHER PTHR35011 3 40 1.2E-20 T 22-04-2016 HRM2_RS01555 dc5b552e2d5a95596e10c58903462d62 200 PANTHER PTHR35011 59 195 1.2E-20 T 22-04-2016 HRM2_RS12740 7c93ad4994e6ec3273f4fcb56426a5be 256 SUPERFAMILY SSF109998 29 155 4.71E-6 T 22-04-2016 IPR027304 Trigger factor/SurA domain HRM2_RS12145 7ebce28bacdb4aed7ee19a9e0d0407a2 348 Pfam PF02470 MlaD protein 53 120 2.0E-6 T 22-04-2016 IPR003399 Mce/MlaD HRM2_RS18985 5e11fd674b76b2df465f401d393ea941 246 Gene3D G3DSA:3.40.50.1860 52 107 1.6E-4 T 22-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HRM2_RS16085 f4479beb3d988e97cd80348a1d800f81 323 Pfam PF14238 Domain of unknown function (DUF4340) 65 240 5.3E-27 T 22-04-2016 IPR025641 Domain of unknown function DUF4340 HRM2_RS14625 a422ad1bde7911498ddd73bef03ee43a 499 Pfam PF01609 Transposase DDE domain 260 474 3.5E-5 T 22-04-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 HRM2_RS13345 93dd12356e98473afe2f577cbacd27f5 251 PANTHER PTHR33514 7 224 6.5E-24 T 22-04-2016 HRM2_RS13345 93dd12356e98473afe2f577cbacd27f5 251 Pfam PF02361 Cobalt transport protein 19 221 3.7E-29 T 22-04-2016 IPR003339 ABC/ECF transporter, transmembrane component HRM2_RS24995 959bd696b02e1dbcc2884091b07ca0a9 1549 Gene3D G3DSA:1.10.150.280 1473 1529 2.7E-5 T 22-04-2016 HRM2_RS21045 9e0d6f0d2b8aed3f529f97fbe40846b5 177 Pfam PF03692 Putative zinc- or iron-chelating domain 31 101 2.2E-7 T 22-04-2016 IPR005358 Putative zinc- or iron-chelating domain containing protein HRM2_RS12685 865418d160c142e4c2dd682be46ad406 105 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 25 96 7.0E-18 T 22-04-2016 IPR008792 Coenzyme PQQ synthesis D UniPathway: UPA00539 HRM2_RS11510 d9f111a5d9d84b3e2b5dd4590a388fbd 123 Pfam PF07027 Protein of unknown function (DUF1318) 35 123 4.5E-21 T 22-04-2016 IPR008309 Uncharacterised conserved protein UCP025560 HRM2_RS10220 79d740a1c740122a36f3949864b179af 128 Pfam PF11171 Protein of unknown function (DUF2958) 28 94 5.0E-7 T 22-04-2016 IPR021341 Protein of unknown function DUF2958 HRM2_RS20660 8f6c5511703b12a4b8f46bbf3c1f67c4 396 SUPERFAMILY SSF56935 32 396 2.44E-16 T 22-04-2016 HRM2_RS02235 95037fbbae1b8dd33ec726551f581a8d 247 Pfam PF03692 Putative zinc- or iron-chelating domain 18 115 1.4E-10 T 22-04-2016 IPR005358 Putative zinc- or iron-chelating domain containing protein HRM2_RS17170 b3edc3357235d4493a8fbd78f8cc5859 328 Gene3D G3DSA:1.10.101.10 7 89 4.4E-8 T 22-04-2016 IPR002477 Peptidoglycan binding-like HRM2_RS25415 2c2a699f9ba794a0e3500cdf4f331338 238 Pfam PF01713 Smr domain 153 236 3.6E-10 T 22-04-2016 IPR002625 Smr domain HRM2_RS25415 2c2a699f9ba794a0e3500cdf4f331338 238 SUPERFAMILY SSF160443 152 236 1.83E-8 T 22-04-2016 IPR002625 Smr domain HRM2_RS02495 290e371d702f237a5745fc177042a87f 317 Pfam PF07949 YbbR-like protein 145 216 1.3E-8 T 22-04-2016 IPR012505 YbbR-like HRM2_RS15550 943ec32d4ebffdf60a0ed4c176362037 510 SUPERFAMILY SSF69318 183 253 2.44E-10 T 22-04-2016 HRM2_RS15550 943ec32d4ebffdf60a0ed4c176362037 510 SUPERFAMILY SSF69318 375 480 2.44E-10 T 22-04-2016 HRM2_RS15550 943ec32d4ebffdf60a0ed4c176362037 510 Gene3D G3DSA:2.130.10.130 364 481 1.1E-4 T 22-04-2016 HRM2_RS19870 e6581dfabd92fa516fbe700311d4f18a 419 SUPERFAMILY SSF56059 12 213 4.12E-5 T 22-04-2016 HRM2_RS24180 b4863699be52bc675efd35f06ceb54f0 554 Gene3D G3DSA:3.30.420.10 147 288 5.9E-4 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HRM2_RS10645 4dc9ff857175bd260786cbc13b09ae36 156 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 23 151 3.5E-20 T 22-04-2016 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component HRM2_RS15160 2cf6d75299adcde6eddf554794824002 516 Pfam PF14574 Domain of unknown function (DUF4445) 88 496 3.4E-127 T 22-04-2016 IPR027980 Protein of unknown function DUF4445 HRM2_RS14905 d809481f8558eb903ac746b995b99e0e 138 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 8 28 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site HRM2_RS00040 df37d95527dff6c797745997101b68d1 263 Pfam PF11932 Protein of unknown function (DUF3450) 18 257 3.6E-70 T 22-04-2016 IPR016866 Uncharacterised conserved protein UCP028069 HRM2_RS12655 c54214fad8a9188a78394df6551eb5ac 348 Pfam PF14907 Uncharacterised nucleotidyltransferase 12 232 6.5E-41 T 22-04-2016 HRM2_RS16670 45728f5a2953cefab6c2f39ec6cbac7c 92 TIGRFAM TIGR04076 TIGR04076: TIGR04076 family protein 1 91 1.4E-23 T 22-04-2016 IPR023811 Conserved hypothetical protein CHP04076 HRM2_RS10415 59868a7b3ba333ea0d1ba197e5bc8136 336 Gene3D G3DSA:1.10.10.700 21 50 1.8E-4 T 22-04-2016 HRM2_RS14460 45bf09434740ca0c1f560de2235616ff 463 Pfam PF13411 MerR HTH family regulatory protein 10 75 1.4E-4 T 22-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HRM2_RS14755 043d4bf9b715acc4c8b885ec6f640073 477 Pfam PF16822 SGNH hydrolase-like domain, acetyltransferase AlgX 99 277 2.7E-18 T 22-04-2016 IPR031811 AlgX, SGNH hydrolase-like domain KEGG: 00061+2.3.1.-|KEGG: 00253+2.3.1.-|KEGG: 00261+2.3.1.-|KEGG: 00310+2.3.1.-|KEGG: 00330+2.3.1.-|KEGG: 00332+2.3.1.-|KEGG: 00340+2.3.1.-|KEGG: 00350+2.3.1.-|KEGG: 00564+2.3.1.-|KEGG: 00565+2.3.1.-|KEGG: 00604+2.3.1.-|KEGG: 00623+2.3.1.-|KEGG: 00626+2.3.1.-|KEGG: 00627+2.3.1.-|KEGG: 00642+2.3.1.-|KEGG: 00650+2.3.1.-|KEGG: 00680+2.3.1.-|KEGG: 00903+2.3.1.-|KEGG: 00904+2.3.1.-|KEGG: 00906+2.3.1.-|KEGG: 00940+2.3.1.-|KEGG: 00942+2.3.1.-|KEGG: 00950+2.3.1.-|KEGG: 00960+2.3.1.-|KEGG: 00965+2.3.1.-|UniPathway: UPA00286 HRM2_RS10040 b040177a0ae0429a69eb0f9ca5164d67 160 Pfam PF07592 Rhodopirellula transposase DDE domain 4 156 2.6E-32 T 22-04-2016 IPR011518 Transposase, Rhodopirellula-type HRM2_RS23500 e1c3ff31f50cd08710288200c902f446 140 Pfam PF12646 Domain of unknown function (DUF3783) 81 136 1.5E-16 T 22-04-2016 IPR016621 Uncharacterised conserved protein UCP014543 HRM2_RS03740 06aac72060d1c8565892d47044c668cb 221 Pfam PF07796 Protein of unknown function (DUF1638) 39 207 6.2E-21 T 22-04-2016 IPR012437 Domain of unknown function DUF1638 HRM2_RS06375 5c3756002ef5a34ee938e08747ecba65 341 SUPERFAMILY SSF51726 44 292 4.97E-11 T 22-04-2016