locus-tag	class	description
FCL45_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
FCL45_RS00015	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FCL45_RS00020	ENOG4108JA2	transcriptioN-repair coupling factor
FCL45_RS00025	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
FCL45_RS00030	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
FCL45_RS00035	ENOG4107QX3	carboxylase
FCL45_RS00045	ENOG4108JIK	carboxylase
FCL45_RS00080	ENOG4107RCI	amp-dependent synthetase and ligase
FCL45_RS00085	ENOG4105DEU	major facilitator superfamily
FCL45_RS00095	ENOG4105CHM	Aminotransferase
FCL45_RS00115	ENOG41073TP	transcriptional regulator
FCL45_RS00120	ENOG4105CGD	Nad-dependent epimerase dehydratase
FCL45_RS00130	ENOG4107QNK	)-transporter
FCL45_RS00135	ENOG4105QUH	Domain of unknown function (DUF2088)
FCL45_RS00140	ENOG4105DNZ	Alpha Beta Hydrolase
FCL45_RS00155	ENOG4105CH2	amidohydrolase
FCL45_RS00190	ENOG4108JUA	Transcriptional regulator
FCL45_RS00205	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
FCL45_RS00210	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
FCL45_RS00215	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL45_RS00220	ENOG4108IJ0	Aspartate ammonia-lyase
FCL45_RS00225	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
FCL45_RS00235	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
FCL45_RS00240	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
FCL45_RS00245	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FCL45_RS00250	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FCL45_RS00255	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
FCL45_RS00260	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
FCL45_RS00275	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
FCL45_RS00280	ENOG4108VGW	abc transporter atp-binding protein
FCL45_RS00285	ENOG4105CXZ	ABC transporter, permease
FCL45_RS00290	ENOG4105VNH	ABC transporter solute-binding protein
FCL45_RS00295	ENOG4107SVH	Potassium channel protein
FCL45_RS00305	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
FCL45_RS00315	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
FCL45_RS00320	ENOG4105EB3	Histidine kinase
FCL45_RS00380	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS00385	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS00395	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
FCL45_RS00405	ENOG4105ECQ	AraC Family Transcriptional Regulator
FCL45_RS00425	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS00440	ENOG4105H1G	trap transporter solute receptor taxi family
FCL45_RS00450	ENOG4105CQB	FAD linked oxidase domain protein
FCL45_RS00470	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
FCL45_RS00475	ENOG4107QMS	site-determining protein
FCL45_RS00480	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
FCL45_RS00490	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
FCL45_RS00505	ENOG4105CDA	abc transporter atp-binding protein
FCL45_RS00510	ENOG4105DRP	amino acid AbC transporter
FCL45_RS00515	ENOG4105EZ7	amino acid ABC transporter
FCL45_RS00520	ENOG4107QXX	ABC transporter
FCL45_RS00525	ENOG4105F0I	Aminotransferase
FCL45_RS00530	ENOG4107S8C	mandelate racemase muconate lactonizing
FCL45_RS00540	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
FCL45_RS00550	ENOG4105DC7	peptidase M24
FCL45_RS00580	ENOG4105E33	succinate dehydrogenase
FCL45_RS00585	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
FCL45_RS00610	ENOG4105C3M	thioredoxin reductase
FCL45_RS00615	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
FCL45_RS00620	ENOG4105ECY	inositol monophosphatase
FCL45_RS00625	ENOG4107QM5	aconitate hydratase
FCL45_RS00650	ENOG4105CJ1	ABC, transporter
FCL45_RS00660	ENOG4105CUZ	uba thif-type nad fad binding protein
FCL45_RS00665	ENOG4107XID	2'-5' rna ligase
FCL45_RS00705	ENOG41086KC	Transcriptional regulator
FCL45_RS00710	ENOG4108XDW	curli assembly protein CsgE
FCL45_RS00720	ENOG4105P8Q	Curli production assembly transport component CsgG
FCL45_RS00735	ENOG4105KVH	Transcriptional regulator
FCL45_RS00745	ENOG41084UG	Pfam:DUF1458
FCL45_RS00780	ENOG4107YCY	Transcriptional regulator
FCL45_RS00790	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
FCL45_RS00795	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
FCL45_RS00800	ENOG4105NAU	thioesterase Superfamily protein
FCL45_RS00805	ENOG4105DKW	ABC transporter
FCL45_RS00830	ENOG4107SVV	electron transport complex, RnfABCDGE type, B subunit
FCL45_RS00835	ENOG4105DGN	Electron transport complex
FCL45_RS00840	ENOG4105DZB	Electron transport complex
FCL45_RS00845	ENOG41080WF	Electron transport complex, RnfABCDGE type, G subunit
FCL45_RS00850	ENOG4105D6A	Electron transport complex
FCL45_RS00855	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
FCL45_RS00860	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
FCL45_RS00875	ENOG4105CQ7	ATP-dependent helicase
FCL45_RS00930	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
FCL45_RS00945	ENOG4105C9M	aspartyl-trna synthetase
FCL45_RS00950	ENOG4105CUT	histidyl-tRNA synthetase
FCL45_RS00955	ENOG4105EA8	2-Nitropropane dioxygenase
FCL45_RS00960	ENOG4105DJ0	Poly(A) Polymerase
FCL45_RS00965	ENOG4105E3S	small subunit
FCL45_RS00970	ENOG4105DPX	Hydrogenase, large subunit
FCL45_RS00990	ENOG4105CQS	hydrogenase expression formation protein HypD
FCL45_RS00995	ENOG4105C45	hydrogenase expression formation protein (HypE)
FCL45_RS01000	ENOG4108USZ	hydrogenase
FCL45_RS01015	ENOG4108IGT	Dipeptidase
FCL45_RS01020	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
FCL45_RS01040	ENOG4107RSD	Multi-copper polyphenol oxidoreductase laccase
FCL45_RS01060	ENOG4108YZA	Nitrogen regulatory protein pii
FCL45_RS01070	ENOG4108JUA	Transcriptional regulator
FCL45_RS01075	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
FCL45_RS01085	ENOG4108YZA	Nitrogen regulatory protein pii
FCL45_RS01100	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
FCL45_RS01125	ENOG4105EX9	Membrane
FCL45_RS01145	ENOG4105EJ9	Membrane
FCL45_RS01155	ENOG4107XQ1	cobalamin (vitamin B12) biosynthesis CbiM protein
FCL45_RS01160	ENOG4108A51	
FCL45_RS01175	ENOG4108JJB	ABC transporter
FCL45_RS01195	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
FCL45_RS01200	ENOG4105CDV	Ompa motb domain protein
FCL45_RS01210	ENOG4105CYC	Transferase
FCL45_RS01215	ENOG4105C6K	Malic enzyme
FCL45_RS01225	ENOG4105ED1	spovr family
FCL45_RS01240	ENOG4105KME	endoribonuclease L-psp
FCL45_RS01245	ENOG4105CEM	UPF0597 protein
FCL45_RS01250	ENOG4108ETH	Formylglycinamide ribotide synthetase
FCL45_RS01275	ENOG4108UXE	Protein tyrosine phosphatase
FCL45_RS01295	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
FCL45_RS01320	ENOG4105C7H	Helicase, RecD TraA family
FCL45_RS01365	ENOG4105BZU	Histidine kinase
FCL45_RS01385	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
FCL45_RS01395	ENOG4108UQY	Iron-storage protein
FCL45_RS01405	ENOG4107EFR	Flavocytochrome c
FCL45_RS01410	ENOG4107EFR	Flavocytochrome c
FCL45_RS01435	ENOG4105BZU	Histidine kinase
FCL45_RS01440	ENOG4105CFG	Acts as a chaperone (By similarity)
FCL45_RS01445	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
FCL45_RS01460	ENOG4105D6U	Sodium Glutamate Symporter
FCL45_RS01480	ENOG4105CD5	CoA-binding domain protein
FCL45_RS01520	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
FCL45_RS01525	ENOG4108JUA	Transcriptional regulator
FCL45_RS01535	ENOG4108JUB	Transcriptional regulator
FCL45_RS01550	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL45_RS01585	ENOG4105BZU	Histidine kinase
FCL45_RS01640	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
FCL45_RS01665	ENOG4107PP3	Acetylornithine deacetylase
FCL45_RS01670	ENOG4108RWI	nicotinamidase
FCL45_RS01675	ENOG4105DAP	Nicotinate phosphoribosyltransferase
FCL45_RS01685	ENOG4108TKH	Nitroreductase
FCL45_RS01690	ENOG4105CKK	Glycosyl transferase, family 2
FCL45_RS01700	ENOG4108VDT	Glycosyl transferase family protein
FCL45_RS01705	ENOG4105CG5	Glycosyl transferase (Group 1
FCL45_RS01710	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
FCL45_RS01715	ENOG4105C4M	(Ubiquinol oxidase) subunit I
FCL45_RS01725	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
FCL45_RS01735	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
FCL45_RS01770	ENOG4105JNK	Glycosyl transferase (Group 1
FCL45_RS01780	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS01785	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
FCL45_RS01790	ENOG4107QR9	Iron-sulfur cluster binding protein
FCL45_RS01800	ENOG4105CBP	Major Facilitator
FCL45_RS01820	ENOG4108UTP	(2Fe-2S)-binding domain protein
FCL45_RS01825	ENOG4105C7W	Xanthine dehydrogenase
FCL45_RS01830	ENOG4105MJ6	selenium-dependent hydroxylase accessory protein YqeC
FCL45_RS01840	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
FCL45_RS01845	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
FCL45_RS01855	ENOG4105C3G	gtp-binding protein
FCL45_RS01860	ENOG4105D0M	Protease HtpX homolog
FCL45_RS01880	ENOG4105DG4	malate L-lactate dehydrogenase
FCL45_RS01895	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
FCL45_RS01905	ENOG4108BGM	Quinol dehydrogenase periplasmic component
FCL45_RS01915	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
FCL45_RS01925	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
FCL45_RS01935	ENOG4108UT2	hemolysin iii
FCL45_RS01940	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FCL45_RS01945	ENOG4108UVJ	appr-1-p processing domain protein
FCL45_RS01950	ENOG4105F1S	paraquat-inducible protein a
FCL45_RS01955	ENOG4105DY2	Paraquat-inducible protein b
FCL45_RS01965	ENOG4107FQ9	ethanolamine ammonia-lyase
FCL45_RS01970	ENOG4105CPD	ethanolamine ammonia-lyase
FCL45_RS01975	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL45_RS01990	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
FCL45_RS01995	ENOG4105CFH	Aspartokinase
FCL45_RS02010	ENOG4105E5H	Transposase
FCL45_RS02135	ENOG4105CFP	Peptidase U32
FCL45_RS02155	ENOG4105CHU	acetyl-coa acetyltransferase
FCL45_RS02160	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
FCL45_RS02165	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
FCL45_RS02175	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL45_RS02185	ENOG4105CH5	extracellular solute-binding protein, family 7
FCL45_RS02190	ENOG4105CY0	Metallo-Beta-Lactamase
FCL45_RS02200	ENOG4105VEQ	Cold shock protein
FCL45_RS02210	ENOG4105M71	acetolactate synthase 1 regulatory subunit
FCL45_RS02215	ENOG4105C7K	acetolactate synthase
FCL45_RS02220	ENOG4105C0A	alcohol dehydrogenase
FCL45_RS02225	ENOG4105BZU	Histidine kinase
FCL45_RS02250	ENOG4105F1A	Pyruvate formate-lyase
FCL45_RS02255	ENOG4105C6N	Formate acetyltransferase
FCL45_RS02260	ENOG4105CGF	Aromatic amino acid aminotransferase
FCL45_RS02270	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
FCL45_RS02275	ENOG4105C6K	Malic enzyme
FCL45_RS02280	ENOG4105CH5	extracellular solute-binding protein, family 7
FCL45_RS02285	ENOG4107PPM	cobalt chelatase
FCL45_RS02290	ENOG4107RA9	decarboxylase
FCL45_RS02305	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FCL45_RS02315	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FCL45_RS02320	ENOG4108JQ7	(ABC) transporter
FCL45_RS02325	ENOG4105C3U	ABC transporter
FCL45_RS02330	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FCL45_RS02335	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
FCL45_RS02340	ENOG4107QSI	ABC, transporter
FCL45_RS02350	ENOG41082X2	rubredoxin
FCL45_RS02355	ENOG4108IYU	L-aspartate oxidase
FCL45_RS02375	ENOG4107SVN	transposase
FCL45_RS02395	ENOG41081QV	Universal stress protein
FCL45_RS02425	ENOG4105CJW	magnesium transporter
FCL45_RS02435	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
FCL45_RS02440	ENOG4105EMY	transcriptional regulator
FCL45_RS02445	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
FCL45_RS02450	ENOG4105C1A	potassium transporter peripheral membrane
FCL45_RS02455	ENOG41067CV	Integrase
FCL45_RS02515	ENOG4105C0D	helicase
FCL45_RS02605	ENOG4105E7U	AraC family transcriptional regulator
FCL45_RS02610	ENOG4105N14	lysine exporter protein LysE YggA
FCL45_RS02615	ENOG4105BZU	Histidine kinase
FCL45_RS02620	ENOG4105DY9	regulatoR
FCL45_RS02625	ENOG4108HRK	Histidine kinase
FCL45_RS02655	ENOG4105M4H	endoribonuclease L-psp
FCL45_RS02665	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL45_RS02670	ENOG4105GQU	Trap dicarboxylate transporter, dctp subunit
FCL45_RS02695	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
FCL45_RS02700	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
FCL45_RS02715	ENOG4105CP2	von willebrand factor, type a
FCL45_RS02730	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
FCL45_RS02735	ENOG4105D9Q	decarboxylase (Beta subunit)
FCL45_RS02745	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
FCL45_RS02750	ENOG4107Y6J	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
FCL45_RS02770	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
FCL45_RS02775	ENOG4105DCF	alanine dehydrogenase
FCL45_RS02795	ENOG4108JUB	Transcriptional regulator
FCL45_RS02800	ENOG4105F1A	Pyruvate formate-lyase
FCL45_RS02805	ENOG4105C6N	Formate acetyltransferase
FCL45_RS02810	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL45_RS02815	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
FCL45_RS02840	ENOG4107QP3	malate synthase g
FCL45_RS02845	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
FCL45_RS02895	ENOG4105E0X	reductase
FCL45_RS02900	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
FCL45_RS02905	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
FCL45_RS02910	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
FCL45_RS02920	ENOG4108R96	Methyltransferase, YaeB family
FCL45_RS02925	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
FCL45_RS02945	ENOG4105NBF	ammecr1 domain protein
FCL45_RS02950	ENOG4105E2T	synthase III
FCL45_RS02955	ENOG4105BZU	Histidine kinase
FCL45_RS02970	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
FCL45_RS02980	ENOG4105KCK	Peptidoglycan-associated lipoprotein
FCL45_RS02985	ENOG4105CAT	Cytidine monophosphate kinase
FCL45_RS02990	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FCL45_RS02995	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
FCL45_RS03000	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FCL45_RS03005	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FCL45_RS03010	ENOG4105CUC	YeeE YedE family protein
FCL45_RS03015	ENOG4105VFE	sira family
FCL45_RS03040	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
FCL45_RS03045	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FCL45_RS03050	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FCL45_RS03055	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
FCL45_RS03060	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
FCL45_RS03065	ENOG4105WPN	DNA integration recombination invertion protein
FCL45_RS03070	ENOG4108JUA	Transcriptional regulator
FCL45_RS03090	ENOG4105FA0	parb-like partition protein
FCL45_RS03095	ENOG4107QJE	Chromosome Partitioning Protein
FCL45_RS03100	ENOG4108IYU	L-aspartate oxidase
FCL45_RS03140	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FCL45_RS03145	ENOG4105W5Q	DNA repair protein (RadC
FCL45_RS03150	ENOG4105CSA	Coproporphyrinogen iii oxidase
FCL45_RS03165	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
FCL45_RS03175	ENOG4105C0H	protease
FCL45_RS03180	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
FCL45_RS03190	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
FCL45_RS03200	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
FCL45_RS03240	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
FCL45_RS03245	ENOG4107XGZ	Hydrolase
FCL45_RS03265	ENOG4105C5Q	Transcriptional regulator
FCL45_RS03275	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
FCL45_RS03290	ENOG4107R8N	Glycosyl transferase, family 2
FCL45_RS03295	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
FCL45_RS03300	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL45_RS03330	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FCL45_RS03335	ENOG4108IUZ	ABC transporter
FCL45_RS03345	ENOG4105CAS	nag kinase
FCL45_RS03350	ENOG4105C8Y	Acetylornithine aminotransferase
FCL45_RS03355	ENOG4105DBV	ornithine carbamoyltransferase
FCL45_RS03360	ENOG4105CDH	Citrulline--aspartate ligase
FCL45_RS03365	ENOG4105CH7	arginosuccinase
FCL45_RS03375	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
FCL45_RS03380	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FCL45_RS03385	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
FCL45_RS03390	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FCL45_RS03400	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
FCL45_RS03405	ENOG4105E4C	Lytic transglycosylase catalytic
FCL45_RS03410	ENOG4105CHH	sulfate transporter
FCL45_RS03420	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FCL45_RS03435	ENOG4105K59	histidine triad (HIT) protein
FCL45_RS03545	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FCL45_RS03555	ENOG4108J5H	Homocysteine s-methyltransferase
FCL45_RS03565	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
FCL45_RS03570	ENOG4106KR7	LysR family Transcriptional regulator
FCL45_RS03580	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
FCL45_RS03585	ENOG4105BZU	Histidine kinase
FCL45_RS03590	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS03595	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS03645	ENOG4105DHT	Metal Dependent Phosphohydrolase
FCL45_RS03650	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
FCL45_RS03680	ENOG4105C1G	acyl-Coa dehydrogenase
FCL45_RS03700	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
FCL45_RS03715	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FCL45_RS03745	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
FCL45_RS03750	ENOG4105EB3	Histidine kinase
FCL45_RS03780	ENOG4108IYU	L-aspartate oxidase
FCL45_RS03820	ENOG4105CGU	Enoyl-CoA hydratase
FCL45_RS03830	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
FCL45_RS03835	ENOG4108J2R	molybdopterin oxidoreductase
FCL45_RS03850	ENOG4105BZU	Histidine kinase
FCL45_RS03855	ENOG4107YZX	Universal stress protein
FCL45_RS03920	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
FCL45_RS03950	ENOG4105R1U	AraC Family Transcriptional Regulator
FCL45_RS03965	ENOG4107R39	(ABC) transporter
FCL45_RS03990	ENOG4105E8R	UPF0173 metal-dependent hydrolase
FCL45_RS04000	ENOG4105CFC	Transporter
FCL45_RS04005	ENOG4105W3S	hemerythrin-like, metal-binding protein
FCL45_RS04020	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
FCL45_RS04040	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
FCL45_RS04065	ENOG4106V2I	dimethylaminohydrolase
FCL45_RS04075	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FCL45_RS04080	ENOG4105CS2	ec 3.2.1.21
FCL45_RS04135	ENOG4105F8J	Adenylate Guanylate cyclase
FCL45_RS04160	ENOG4108MJI	response regulator
FCL45_RS04165	ENOG4105BZ1	(ABC) transporter
FCL45_RS04165	ENOG4105BZ1	(ABC) transporter
FCL45_RS04180	ENOG41083UI	stage II sporulation protein
FCL45_RS04200	ENOG4105BZU	Histidine kinase
FCL45_RS04205	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
FCL45_RS04210	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
FCL45_RS04215	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
FCL45_RS04230	ENOG4105EGD	dinuclear metal center protein, YbgI family
FCL45_RS04240	ENOG4105D0M	Protease HtpX homolog
FCL45_RS04245	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
FCL45_RS04250	ENOG4107QHF	type ii secretion system protein e
FCL45_RS04255	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
FCL45_RS04265	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
FCL45_RS04275	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
FCL45_RS04280	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FCL45_RS04285	ENOG4105BZA	Phosphoglycerate kinase
FCL45_RS04290	ENOG4105BZA	Phosphoglycerate kinase
FCL45_RS04295	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
FCL45_RS04310	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
FCL45_RS04335	ENOG4105E98	transcriptional regulator DeoR family
FCL45_RS04340	ENOG4105C5I	Dehydrogenase
FCL45_RS04350	ENOG4105C26	Dehydrogenase
FCL45_RS04400	ENOG4107SVH	Potassium channel protein
FCL45_RS04405	ENOG4108ZAI	phosphatidylglycerophosphatase a
FCL45_RS04410	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
FCL45_RS04415	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
FCL45_RS04420	ENOG4105H1G	trap transporter solute receptor taxi family
FCL45_RS04435	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
FCL45_RS04475	ENOG4108RAC	Rubrerythrin
FCL45_RS04485	ENOG4105QNF	Outer membrane lipoprotein
FCL45_RS04505	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
FCL45_RS04510	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
FCL45_RS04515	ENOG4105DAA	L-lactate
FCL45_RS04525	ENOG4105DAA	L-lactate
FCL45_RS04530	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
FCL45_RS04555	ENOG4108IJ9	(ABC) transporter
FCL45_RS04560	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FCL45_RS04565	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
FCL45_RS04570	ENOG4105E98	transcriptional regulator DeoR family
FCL45_RS04580	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
FCL45_RS04585	ENOG4105C2W	permease
FCL45_RS04590	ENOG4105DEF	Extracellular solute-binding protein, family 5
FCL45_RS04595	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
FCL45_RS04600	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FCL45_RS04605	ENOG4105C3U	ABC transporter
FCL45_RS04610	ENOG4108JQ7	(ABC) transporter
FCL45_RS04615	ENOG4105J4Q	Transcriptional regulator
FCL45_RS04620	ENOG4108IUS	Transketolase
FCL45_RS04625	ENOG410829K	Lysine exporter protein (Lyse ygga)
FCL45_RS04640	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
FCL45_RS04655	ENOG4107QWE	)-transporter
FCL45_RS04660	ENOG4107SVN	transposase
FCL45_RS04665	ENOG4105ERH	Fumarylacetoacetate hydrolase
FCL45_RS04680	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
FCL45_RS04685	ENOG4105HF0	Membrane
FCL45_RS04695	ENOG41073TP	transcriptional regulator
FCL45_RS04705	ENOG4107S0N	DJ-1 family
FCL45_RS04715	ENOG4107ZS6	Flavodoxin
FCL45_RS04720	ENOG4105CHH	sulfate transporter
FCL45_RS04745	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
FCL45_RS04755	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
FCL45_RS04775	ENOG4105NF4	modulator of drug activity
FCL45_RS04780	ENOG4108IPT	Naphthoate synthase
FCL45_RS04785	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
FCL45_RS04800	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
FCL45_RS04810	ENOG4108Q71	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
FCL45_RS04815	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
FCL45_RS04825	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FCL45_RS04865	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
FCL45_RS04875	ENOG4108R6G	acetyltransferase
FCL45_RS04880	ENOG4105JQZ	Methyltransferase
FCL45_RS04890	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
FCL45_RS04895	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
FCL45_RS04915	ENOG4106PMH	Extracellular solute-binding protein family 3
FCL45_RS04920	ENOG4105EAD	ABC transporter
FCL45_RS04935	ENOG4105UIB	(ABC) transporter
FCL45_RS04945	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
FCL45_RS04950	ENOG4108JQ9	ABC transporter
FCL45_RS04965	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FCL45_RS04975	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
FCL45_RS04980	ENOG4105CQB	FAD linked oxidase domain protein
FCL45_RS04990	ENOG4105BZU	Histidine kinase
FCL45_RS05000	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
FCL45_RS05010	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
FCL45_RS05030	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL45_RS05050	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
FCL45_RS05050	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
FCL45_RS05055	ENOG4107SEY	Conserved Protein
FCL45_RS05060	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
FCL45_RS05065	ENOG4105CYC	Transferase
FCL45_RS05085	ENOG41074CX	linocin_m18 bacteriocin protein
FCL45_RS05090	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
FCL45_RS05100	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
FCL45_RS05105	ENOG4105DVI	reductase, NrfD
FCL45_RS05110	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
FCL45_RS05115	ENOG4108J2R	molybdopterin oxidoreductase
FCL45_RS05125	ENOG41073TP	transcriptional regulator
FCL45_RS05130	ENOG4105CH5	extracellular solute-binding protein, family 7
FCL45_RS05140	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL45_RS05160	ENOG4108IQE	Amp-dependent synthetase and ligase
FCL45_RS05195	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
FCL45_RS05215	ENOG4108I5C	dEAD DEAH box helicase
FCL45_RS05230	ENOG4105CDU	Replicative dna helicase
FCL45_RS05285	ENOG41064T2	transcriptional regulator, lysR family
FCL45_RS05295	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FCL45_RS05345	ENOG4105CYC	Transferase
FCL45_RS05350	ENOG4105E39	Enoyl-CoA hydratase
FCL45_RS05375	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
FCL45_RS05385	ENOG4105E39	Enoyl-CoA hydratase
FCL45_RS05480	ENOG4105C6N	Formate acetyltransferase
FCL45_RS05485	ENOG4105F1A	Pyruvate formate-lyase
FCL45_RS05495	ENOG4107QXX	ABC transporter
FCL45_RS05500	ENOG4105EZ7	amino acid ABC transporter
FCL45_RS05505	ENOG4105DRP	amino acid AbC transporter
FCL45_RS05510	ENOG4105CDA	abc transporter atp-binding protein
FCL45_RS05525	ENOG4105CDV	Ompa motb domain protein
FCL45_RS05535	ENOG4105CIS	alcohol dehydrogenase
FCL45_RS05540	ENOG4107NQ8	LysR family Transcriptional regulator
FCL45_RS05545	ENOG4105CDV	Ompa motb domain protein
FCL45_RS05550	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
FCL45_RS05565	ENOG4105HMI	Membrane
FCL45_RS05580	ENOG4105BZU	Histidine kinase
FCL45_RS05585	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS05600	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS05610	ENOG4108U5N	UPF0316 protein
FCL45_RS05645	ENOG4105DMF	Dehydrogenase
FCL45_RS05660	ENOG4105C9B	Cysteine desulfurase
FCL45_RS05670	ENOG4105E5Q	amino acid AbC transporter
FCL45_RS05675	ENOG4105E89	ABC transporter
FCL45_RS05680	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FCL45_RS05695	ENOG4107EFR	Flavocytochrome c
FCL45_RS05760	ENOG4107QWE	)-transporter
FCL45_RS05765	ENOG410812K	response regulator receiver protein
FCL45_RS05770	ENOG4108ZXC	Two component transcriptional regulator, luxr family
FCL45_RS05775	ENOG4108JUB	Transcriptional regulator
FCL45_RS05790	ENOG4105ETX	regulatoR
FCL45_RS05795	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
FCL45_RS05810	ENOG4107SVN	transposase
FCL45_RS05820	ENOG4105BZU	Histidine kinase
FCL45_RS05825	ENOG4105MYT	Heat shock protein
FCL45_RS05835	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FCL45_RS05840	ENOG4105CIZ	coA-substrate-specific enzyme activase
FCL45_RS05845	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
FCL45_RS05865	ENOG4105Z0W	Dissimilatory sulfite reductase D
FCL45_RS05945	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
FCL45_RS05950	ENOG4108RA0	tripartite ATP-independent periplasmic transporter, DctQ component
FCL45_RS05955	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL45_RS05960	ENOG4105CQB	FAD linked oxidase domain protein
FCL45_RS06005	ENOG4105BZU	Histidine kinase
FCL45_RS06030	ENOG4105T40	surface antigen msp4 family protein
FCL45_RS06080	ENOG4105C0F	tryptophanase EC 4.1.99.1
FCL45_RS06090	ENOG4105EW9	transcriptional regulator AsnC family
FCL45_RS06100	ENOG4105CNG	UPF0061 protein
FCL45_RS06110	ENOG4105E5J	UV damage endonuclease
FCL45_RS06135	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
FCL45_RS06145	ENOG4105C26	Dehydrogenase
FCL45_RS06155	ENOG4105CM2	brancheD-chain amino acid aminotransferase
FCL45_RS06160	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
FCL45_RS06165	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
FCL45_RS06175	ENOG4105CFI	type iii restriction protein res subunit
FCL45_RS06225	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FCL45_RS06270	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
FCL45_RS06280	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
FCL45_RS06285	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
FCL45_RS06325	ENOG4105C3F	Signal peptidase i
FCL45_RS06330	ENOG4105CXT	aspartate transcarbamylase
FCL45_RS06335	ENOG4105CD3	dihydroorotase
FCL45_RS06340	ENOG4105PW4	Sugar fermentation stimulation protein homolog
FCL45_RS06345	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
FCL45_RS06355	ENOG4105BZA	Phosphoglycerate kinase
FCL45_RS06360	ENOG4105CP7	Triose-phosphate isomerase
FCL45_RS06365	ENOG4107EJC	Preprotein translocase subunit SecG
FCL45_RS06375	ENOG4107RU9	Transcriptional regulator, Crp Fnr family
FCL45_RS06380	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
FCL45_RS06385	ENOG4106HK8	GPR1 FUN34 yaaH family protein
FCL45_RS06420	ENOG4107R1I	NAD-dependent malic enzyme
FCL45_RS06425	ENOG4105EAB	amino acid AbC transporter
FCL45_RS06430	ENOG4105E5Q	amino acid AbC transporter
FCL45_RS06435	ENOG4105CDA	abc transporter atp-binding protein
FCL45_RS06440	ENOG4107RHR	regulatoR
FCL45_RS06445	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
FCL45_RS06450	ENOG4105GQU	Trap dicarboxylate transporter, dctp subunit
FCL45_RS06460	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL45_RS06475	ENOG4105DWD	nucleoside recognition domain protein
FCL45_RS06480	ENOG4105BZU	Histidine kinase
FCL45_RS06495	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS06500	ENOG4105BZU	Histidine kinase
FCL45_RS06510	ENOG4105D63	family UPF0324
FCL45_RS06520	ENOG4105D63	family UPF0324
FCL45_RS06580	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FCL45_RS06610	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
FCL45_RS06615	ENOG4108W6G	cytochrome C
FCL45_RS06620	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
FCL45_RS06655	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
FCL45_RS06665	ENOG4105E3S	small subunit
FCL45_RS06675	ENOG4105E3S	small subunit
FCL45_RS06680	ENOG4105DPX	Hydrogenase, large subunit
FCL45_RS06700	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
FCL45_RS06715	ENOG4105BZU	Histidine kinase
FCL45_RS06725	ENOG4106AXJ	AraC family transcriptional regulator
FCL45_RS06740	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
FCL45_RS06755	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
FCL45_RS06760	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
FCL45_RS06765	ENOG4108VKG	metal-dependent hydrolase
FCL45_RS06770	ENOG4105DR4	Methyltransferase
FCL45_RS06780	ENOG4108JUA	Transcriptional regulator
FCL45_RS06865	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
FCL45_RS06890	ENOG4108Z7R	Chaperone CsaA
FCL45_RS06900	ENOG4105GR3	Histidine kinase
FCL45_RS06905	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FCL45_RS06910	ENOG4105CKK	Glycosyl transferase, family 2
FCL45_RS06915	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
FCL45_RS06920	ENOG4105MRR	Transcriptional regulator (By similarity)
FCL45_RS06935	ENOG4105EAD	ABC transporter
FCL45_RS06940	ENOG4105EAB	amino acid AbC transporter
FCL45_RS06945	ENOG4105E5Q	amino acid AbC transporter
FCL45_RS06960	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
FCL45_RS07005	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
FCL45_RS07015	ENOG4105BZU	Histidine kinase
FCL45_RS07020	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS07030	ENOG4105CEY	Amp-dependent synthetase and ligase
FCL45_RS07045	ENOG4105BZU	Histidine kinase
FCL45_RS07050	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS07060	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
FCL45_RS07075	ENOG41067SE	Tetr family transcriptional regulator
FCL45_RS07110	ENOG4105BZU	Histidine kinase
FCL45_RS07120	ENOG4105KVH	Transcriptional regulator
FCL45_RS07130	ENOG4108YXU	transcriptional regulator AsnC family
FCL45_RS07140	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
FCL45_RS07145	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
FCL45_RS07150	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
FCL45_RS07160	ENOG4105DYY	Reactivating factor for ethanolamine ammonia lyase
FCL45_RS07165	ENOG4107FQ9	ethanolamine ammonia-lyase
FCL45_RS07170	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
FCL45_RS07180	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL45_RS07240	ENOG4105CA9	Pyruvate kinase
FCL45_RS07270	ENOG4108Z0Z	intracellular protease Pfpi family
FCL45_RS07275	ENOG4105S0E	allantoin catabolism protein
FCL45_RS07280	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
FCL45_RS07285	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
FCL45_RS07295	ENOG4105E5Q	amino acid AbC transporter
FCL45_RS07300	ENOG4105DRP	amino acid AbC transporter
FCL45_RS07305	ENOG4107RP9	extracellular solute-binding protein, family 3
FCL45_RS07315	ENOG4105CGY	Dna recombination protein
FCL45_RS07340	ENOG4105KJJ	Uncharacterized ACR, COG1993
FCL45_RS07350	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL45_RS07360	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
FCL45_RS07365	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
FCL45_RS07370	ENOG4107YU2	histidine triad (hIT) protein
FCL45_RS07375	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
FCL45_RS07380	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FCL45_RS07385	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
FCL45_RS07400	ENOG4105D7N	magnesium and cobalt transport protein CorA
FCL45_RS07410	ENOG4105EGS	Mechanosensitive ion channel
FCL45_RS07425	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
FCL45_RS07435	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
FCL45_RS07445	ENOG4105C01	Dihydroxy-acid dehydratase
FCL45_RS07450	ENOG4105CZX	twitching motility protein
FCL45_RS07460	ENOG4105C1J	atp-dependent rna helicase
FCL45_RS07465	ENOG41082J7	Rhodanese domain protein
FCL45_RS07470	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
FCL45_RS07475	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
FCL45_RS07480	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
FCL45_RS07485	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FCL45_RS07490	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FCL45_RS07505	ENOG4105CHC	glucokinase (EC 2.7.1.2)
FCL45_RS07535	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FCL45_RS07550	ENOG4108I0N	Transporter, RarD family, DMT superfamily protein
FCL45_RS07570	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
FCL45_RS07575	ENOG4105C1J	atp-dependent rna helicase
FCL45_RS07585	ENOG4105BZU	Histidine kinase
FCL45_RS07590	ENOG4107R11	Transcriptional regulator
FCL45_RS07595	ENOG4107X42	5-methylthioadenosine S-adenosylhomocysteine nucleosidase
FCL45_RS07600	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
FCL45_RS07615	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
FCL45_RS07625	ENOG41073TP	transcriptional regulator
FCL45_RS07640	ENOG4105CX8	fg-gap repeat protein
FCL45_RS07650	ENOG4108RC0	Electron transport protein
FCL45_RS07655	ENOG4107QHI	-hydrogenase
FCL45_RS07660	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
FCL45_RS07665	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS07670	ENOG4105D41	biosynthesis protein thiH
FCL45_RS07675	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
FCL45_RS07680	ENOG4108IJ0	Aspartate ammonia-lyase
FCL45_RS07685	ENOG4107QW8	radical SAM domain protein
FCL45_RS07695	ENOG4107QHI	-hydrogenase
FCL45_RS07700	ENOG4105S7S	phosphonate abc transporter
FCL45_RS07705	ENOG4105D5T	phosphonate abc transporter
FCL45_RS07710	ENOG4107T9Q	phosphonate abc transporter
FCL45_RS07725	ENOG4105J0Q	Transcriptional regulator
FCL45_RS07765	ENOG4105K8R	UPF0145 protein
FCL45_RS07795	ENOG4106AXJ	AraC family transcriptional regulator
FCL45_RS07810	ENOG4107QUY	Guanine deaminase
FCL45_RS07820	ENOG4107QY8	reductase
FCL45_RS07825	ENOG4107QWJ	nitrate reductase beta subunit
FCL45_RS07845	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
FCL45_RS07850	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS07855	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
FCL45_RS07860	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
FCL45_RS07865	ENOG4105DEF	Extracellular solute-binding protein, family 5
FCL45_RS07880	ENOG4105C3U	ABC transporter
FCL45_RS07885	ENOG4108JQ7	(ABC) transporter
FCL45_RS07895	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
FCL45_RS07905	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
FCL45_RS07915	ENOG4107IFA	Lipase (EC 3.1.1.3)
FCL45_RS07925	ENOG4108IQE	Amp-dependent synthetase and ligase
FCL45_RS07945	ENOG4105DJ4	phosphatidylserine decarboxylase
FCL45_RS07965	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
FCL45_RS07970	ENOG4105CHR	reductase
FCL45_RS07975	ENOG4105CHU	acetyl-coa acetyltransferase
FCL45_RS07980	ENOG4105C94	Transporter
FCL45_RS08005	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
FCL45_RS08010	ENOG4105CE1	Ferrous iron transport protein b
FCL45_RS08015	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
FCL45_RS08035	ENOG4105C94	Transporter
FCL45_RS08045	ENOG41080XP	Cbs domain
FCL45_RS08055	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
FCL45_RS08075	ENOG4105UYK	outer membrane protein a
FCL45_RS08085	ENOG4109066	lysm domain bon superfamily protein
FCL45_RS08100	ENOG4107BVJ	4,5-dihydroxyphthalate decarboxylase
FCL45_RS08145	ENOG4107YD3	Thioesterase
FCL45_RS08150	ENOG4105E3H	phosphoglycerate mutase
FCL45_RS08155	ENOG4105D6E	homoserine dehydrogenase
FCL45_RS08160	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
FCL45_RS08210	ENOG4105C0D	helicase
FCL45_RS08215	ENOG4105EIN	peptidylprolyl cis-trans isomerase
FCL45_RS08220	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
FCL45_RS08225	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
FCL45_RS08240	ENOG4105DR5	peptidase
FCL45_RS08245	ENOG4105C5H	ABC transporter
FCL45_RS08255	ENOG4105D9P	serine threonine protein kinase
FCL45_RS08260	ENOG4105BZU	Histidine kinase
FCL45_RS08265	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS08280	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL45_RS08300	ENOG4107SW0	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
FCL45_RS08305	ENOG4105C5W	Aldolase
FCL45_RS08345	ENOG4107QRS	glycosyltransferase group 2 family protein
FCL45_RS08355	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
FCL45_RS08365	ENOG4105CMR	udp-glucose 4-epimerase
FCL45_RS08405	ENOG4105CQS	hydrogenase expression formation protein HypD
FCL45_RS08450	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FCL45_RS08485	ENOG4108YZG	isomerase
FCL45_RS08500	ENOG4105EYW	Ion transport protein
FCL45_RS08505	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FCL45_RS08510	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
FCL45_RS08515	ENOG4107QKW	extracellular solute-binding protein family 1
FCL45_RS08535	ENOG4108UIN	ybak prolyl-trna synthetase associated region
FCL45_RS08560	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
FCL45_RS08565	ENOG4108UR8	BAX protein
FCL45_RS08570	ENOG4105E09	nadh pyrophosphatase
FCL45_RS08580	ENOG4107SA6	carbon-phosphorus lyase complex accessory protein
FCL45_RS08590	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
FCL45_RS08595	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FCL45_RS08605	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
FCL45_RS08625	ENOG4105DCF	alanine dehydrogenase
FCL45_RS08640	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
FCL45_RS08645	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FCL45_RS08650	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FCL45_RS08655	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FCL45_RS08660	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FCL45_RS08665	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FCL45_RS08695	ENOG4108V0P	LemA family
FCL45_RS08705	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
FCL45_RS08730	ENOG4105DHT	Metal Dependent Phosphohydrolase
FCL45_RS08765	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
FCL45_RS08775	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
FCL45_RS08785	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
FCL45_RS08800	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
FCL45_RS08820	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
FCL45_RS08825	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL45_RS08835	ENOG4105DRR	Transcriptional regulator, GntR family
FCL45_RS08855	ENOG4105K6H	D-cysteine desulfhydrase
FCL45_RS08880	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
FCL45_RS08890	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
FCL45_RS08895	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
FCL45_RS08900	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
FCL45_RS08940	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
FCL45_RS08945	ENOG4105DQU	oxidoreductase, subunit beta
FCL45_RS08950	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
FCL45_RS08955	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
FCL45_RS08970	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
FCL45_RS08975	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
FCL45_RS08980	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
FCL45_RS09045	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
FCL45_RS09055	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL45_RS09065	ENOG4105DRR	Transcriptional regulator, GntR family
FCL45_RS09080	ENOG4105VCQ	rubredoxin
FCL45_RS09085	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
FCL45_RS09095	ENOG4105F9F	transposase
FCL45_RS09110	ENOG4105EPW	hflc protein
FCL45_RS09115	ENOG4107RIZ	hflk protein
FCL45_RS09130	ENOG4108FYC	transcriptional regulator MERR family
FCL45_RS09140	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FCL45_RS09145	ENOG4105DZQ	phospholipase D Transphosphatidylase
FCL45_RS09195	ENOG4105DQU	oxidoreductase, subunit beta
FCL45_RS09210	ENOG4105D82	Glutamate dehydrogenase
FCL45_RS09220	ENOG4105CK7	Sodium proline symporter
FCL45_RS09225	ENOG4105KPY	Small multidrug resistance protein
FCL45_RS09230	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
FCL45_RS09245	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FCL45_RS09260	ENOG4108JUB	Transcriptional regulator
FCL45_RS09275	ENOG4105C0A	alcohol dehydrogenase
FCL45_RS09280	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
FCL45_RS09295	ENOG4105EWV	Sodium calcium exchanger membrane region
FCL45_RS09305	ENOG4107SGM	protein serine threonine phosphatase
FCL45_RS09310	ENOG4108Z0R	Transferase
FCL45_RS09335	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FCL45_RS09345	ENOG4107NA1	Endonuclease Exonuclease phosphatase
FCL45_RS09350	ENOG4108UQV	Membrane
FCL45_RS09360	ENOG4107STQ	Multicopper oxidase
FCL45_RS09365	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
FCL45_RS09420	ENOG4107VAM	peptidase, m28
FCL45_RS09445	ENOG4105DVA	methyltransferase
FCL45_RS09465	ENOG4108Z5K	methylglyoxal synthase
FCL45_RS09485	ENOG4108Z66	YbaK ebsC protein
FCL45_RS09500	ENOG4105CHU	acetyl-coa acetyltransferase
FCL45_RS09505	ENOG4105C1G	acyl-Coa dehydrogenase
FCL45_RS09515	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FCL45_RS09545	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL45_RS09550	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL45_RS09555	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
FCL45_RS09625	ENOG4105C1J	atp-dependent rna helicase
FCL45_RS09635	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
FCL45_RS09640	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
FCL45_RS09645	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL45_RS09655	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
FCL45_RS09665	ENOG4105CHR	reductase
FCL45_RS09675	ENOG4107FQ9	ethanolamine ammonia-lyase
FCL45_RS09685	ENOG4105E98	transcriptional regulator DeoR family
FCL45_RS09695	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FCL45_RS09720	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
FCL45_RS09725	ENOG4105E0F	Histidine kinase
FCL45_RS09750	ENOG4108JJB	ABC transporter
FCL45_RS09770	ENOG4105D38	putrescine abc transporter
FCL45_RS09775	ENOG4105F38	ABC transporter, permease
FCL45_RS09780	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FCL45_RS09785	ENOG4107RUE	extracellular solute-binding protein family 1
FCL45_RS09790	ENOG4105CHR	reductase
FCL45_RS09795	ENOG4107TFB	basic membrane
FCL45_RS09800	ENOG4108JQ9	ABC transporter
FCL45_RS09805	ENOG41083U2	ABC transporter, permease
FCL45_RS09815	ENOG4105DZC	cytosine deaminase
FCL45_RS09820	ENOG41085PJ	rdd domain containing protein
FCL45_RS09845	ENOG4105CZQ	inner membrane transport protein YdhC
FCL45_RS09865	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL45_RS09870	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
FCL45_RS09875	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
FCL45_RS09895	ENOG4108Z86	Glutamine amidotransferase
FCL45_RS09900	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
FCL45_RS09905	ENOG4108JQ7	(ABC) transporter
FCL45_RS09910	ENOG4105C3U	ABC transporter
FCL45_RS09915	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FCL45_RS09920	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
FCL45_RS09925	ENOG4105DEF	Extracellular solute-binding protein, family 5
FCL45_RS09945	ENOG4105D9M	gamma-glutamylcysteine synthetase
FCL45_RS09970	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
FCL45_RS09975	ENOG4105D3W	isochorismatase
FCL45_RS09980	ENOG4105C8Y	Acetylornithine aminotransferase
FCL45_RS09985	ENOG4108QSZ	General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity)
FCL45_RS09990	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FCL45_RS09995	ENOG4107QSA	Oxaloacetate decarboxylase
FCL45_RS10000	ENOG4105DMQ	Methyltransferase
FCL45_RS10005	ENOG4107SWG	transcriptional regulator MERR family
FCL45_RS10010	ENOG4105C1G	acyl-Coa dehydrogenase
FCL45_RS10015	ENOG4105DF6	Fe-S oxidoreductase
FCL45_RS10020	ENOG4105BZJ	Electron transfer flavoprotein
FCL45_RS10025	ENOG4105C10	Electron transfer flavoprotein
FCL45_RS10035	ENOG4108TGP	Thioesterase superfamily protein
FCL45_RS10040	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
FCL45_RS10050	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FCL45_RS10055	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
FCL45_RS10075	ENOG4105FDK	ABC transporter
FCL45_RS10080	ENOG4107VVP	(ABC) transporter
FCL45_RS10085	ENOG4107R7I	amino acid
FCL45_RS10100	ENOG4105BZU	Histidine kinase
FCL45_RS10105	ENOG4105CPQ	Dehydrogenase
FCL45_RS10110	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FCL45_RS10130	ENOG4106PMH	Extracellular solute-binding protein family 3
FCL45_RS10135	ENOG4105DRP	amino acid AbC transporter
FCL45_RS10150	ENOG4105DIK	(ABC) transporter
FCL45_RS10155	ENOG4105CC5	ABC transporter
FCL45_RS10160	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
FCL45_RS10165	ENOG4105C4M	(Ubiquinol oxidase) subunit I
FCL45_RS10170	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FCL45_RS10225	ENOG4105CHR	reductase
FCL45_RS10235	ENOG4105DE4	1-phosphofructokinase
FCL45_RS10240	ENOG4105D2N	Aldolase
FCL45_RS10255	ENOG4108YZN	class I peptide chain release factor
FCL45_RS10275	ENOG4108YZY	peptidylprolyl cis-trans isomerase
FCL45_RS10295	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
FCL45_RS10300	ENOG4108NIW	Leucine export protein LeuE
FCL45_RS10325	ENOG4108JUB	Transcriptional regulator
FCL45_RS10335	ENOG4105EJQ	L-serine dehydratase
FCL45_RS10340	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
FCL45_RS10355	ENOG4105CIR	epoxide hydrolase
FCL45_RS10365	ENOG4105E0Y	RtcB Protein
FCL45_RS10370	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
FCL45_RS10385	ENOG4105DRS	transport system, permease
FCL45_RS10390	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
FCL45_RS10400	ENOG4105D3G	Pseudouridine synthase
FCL45_RS10410	ENOG4105E27	serine threonine protein kinase
FCL45_RS10420	ENOG4107YTP	response regulator receiver protein
FCL45_RS10425	ENOG4105UQX	Mate efflux family protein
FCL45_RS10440	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
FCL45_RS10465	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
FCL45_RS10475	ENOG4105C7J	ABC transporter, permease
FCL45_RS10485	ENOG4108W15	Protein of unknown function (DUF1456)
FCL45_RS10520	ENOG410812K	response regulator receiver protein
FCL45_RS10525	ENOG4107QSI	ABC, transporter
FCL45_RS10530	ENOG4105BZU	Histidine kinase
FCL45_RS10535	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS10580	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
FCL45_RS10620	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
FCL45_RS10625	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
FCL45_RS10635	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
FCL45_RS10640	ENOG4105Y7M	Transcriptional regulator, TetR family
FCL45_RS10675	ENOG4105DU6	RNA polymerase
FCL45_RS10700	ENOG4105ENH	Sulfatase
FCL45_RS10710	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
FCL45_RS10720	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
FCL45_RS10735	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
FCL45_RS10760	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FCL45_RS10815	ENOG4107PBV	potassium channel
FCL45_RS10820	ENOG4108MJI	response regulator
FCL45_RS10830	ENOG4105ECQ	AraC Family Transcriptional Regulator
FCL45_RS10835	ENOG4108W2Y	isochorismatase
FCL45_RS10840	ENOG4105C8P	)-transporter
FCL45_RS10855	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
FCL45_RS10890	ENOG4105C1G	acyl-Coa dehydrogenase
FCL45_RS10895	ENOG4107QX3	carboxylase
FCL45_RS10910	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
FCL45_RS10915	ENOG4107T4Z	adenosine kinase
FCL45_RS10930	ENOG4105CP9	extracellular ligand-binding receptor
FCL45_RS10935	ENOG4105BZU	Histidine kinase
FCL45_RS10990	ENOG4107SGM	protein serine threonine phosphatase
FCL45_RS11015	ENOG410841Q	phosphoesterase PA-phosphatase related protein
FCL45_RS11020	ENOG4105BZ8	glutamate synthase
FCL45_RS11025	ENOG4105CBC	glutamate synthase
FCL45_RS11040	ENOG4108DBC	nitroreductase
FCL45_RS11055	ENOG4105E5Q	amino acid AbC transporter
FCL45_RS11065	ENOG4105E5Q	amino acid AbC transporter
FCL45_RS11070	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
FCL45_RS11100	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
FCL45_RS11105	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
FCL45_RS11110	ENOG4108YBP	pseudouridine synthase
FCL45_RS11115	ENOG4105C1J	atp-dependent rna helicase
FCL45_RS11125	ENOG4105PTV	Nudix Hydrolase
FCL45_RS11140	ENOG4105C32	Amino acid ABC transporter (Permease)
FCL45_RS11155	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
FCL45_RS11160	ENOG4105C0Z	ABC transporter
FCL45_RS11165	ENOG4105DZS	Phenylacetate-CoA ligase
FCL45_RS11175	ENOG4105CK7	Sodium proline symporter
FCL45_RS11195	ENOG4105HMI	Membrane
FCL45_RS11200	ENOG4105DUM	transcriptional regulator, lysR family
FCL45_RS11205	ENOG4105G6Z	alkaline phosphatase
FCL45_RS11215	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FCL45_RS11225	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
FCL45_RS11230	ENOG4105C5H	ABC transporter
FCL45_RS11235	ENOG4105C5H	ABC transporter
FCL45_RS11240	ENOG4105D5P	Methylmalonyl-coA mutase
FCL45_RS11255	ENOG4107QN2	dihydrolipoyl dehydrogenase
FCL45_RS11260	ENOG4105C7S	Dehydrogenase
FCL45_RS11265	ENOG4105CPP	Dehydrogenase, E1 component
FCL45_RS11270	ENOG4107RUY	(E1 component), alpha subunit
FCL45_RS11280	ENOG4105EMK	carboxylate amino acid amine transporter
FCL45_RS11295	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
FCL45_RS11300	ENOG4105C8U	phosphate abc transporter
FCL45_RS11305	ENOG4105E2Z	phosphate ABC transporter (Permease
FCL45_RS11310	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
FCL45_RS11355	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
FCL45_RS11395	ENOG4105CKW	Inner membrane protein yedI
FCL45_RS11435	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
FCL45_RS11440	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
FCL45_RS11445	ENOG4108YI8	ABC transporter
FCL45_RS11450	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
FCL45_RS11455	ENOG4107Z6I	Thiamine biosynthesis protein
FCL45_RS11515	ENOG4105FR1	rard protein
FCL45_RS11525	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FCL45_RS11535	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
FCL45_RS11540	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
FCL45_RS11545	ENOG4105ETE	Transcriptional regulator (LacI family
FCL45_RS11565	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
FCL45_RS11575	ENOG4105BZM	domain protein
FCL45_RS11590	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FCL45_RS11595	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
FCL45_RS11600	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
FCL45_RS11605	ENOG4105CHR	reductase
FCL45_RS11615	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
FCL45_RS11620	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
FCL45_RS11655	ENOG410826D	Involved in DNA repair and RecF pathway recombination (By similarity)
FCL45_RS11665	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
FCL45_RS11680	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
FCL45_RS11690	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
FCL45_RS11700	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
FCL45_RS11715	ENOG4105CN1	protease
FCL45_RS11740	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
FCL45_RS11760	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
FCL45_RS11765	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
FCL45_RS11770	ENOG4105FF2	Type I DHQase
FCL45_RS11775	ENOG4105E2X	shikimate dehydrogenase
FCL45_RS11780	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
FCL45_RS11795	ENOG4105CVE	Lytic murein transglycosylase
FCL45_RS11805	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
FCL45_RS11810	ENOG4107QQB	Ribonuclease E
FCL45_RS11860	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS11880	ENOG4105CPN	adenine deaminase
FCL45_RS11890	ENOG4107RM6	sulfurtransferase
FCL45_RS11990	ENOG4105D7Q	type ii secretion system
FCL45_RS12000	ENOG4108VAU	general secretion pathway protein G
FCL45_RS12010	ENOG4105X5Z	General secretion pathway protein I
FCL45_RS12045	ENOG4105GVR	general secretion pathway protein D
FCL45_RS12050	ENOG4107QHF	type ii secretion system protein e
FCL45_RS12060	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
FCL45_RS12065	ENOG4105Q84	sucrose synthase
FCL45_RS12070	ENOG4105Q84	sucrose synthase
FCL45_RS12075	ENOG4105DUM	transcriptional regulator, lysR family
FCL45_RS12080	ENOG4105C6T	cysteine synthase
FCL45_RS12085	ENOG4105D7W	serine acetyltransferase
FCL45_RS12090	ENOG4105DTA	methyltransferase
FCL45_RS12095	ENOG4105DWV	Homoserine O-trans-acetylase
FCL45_RS12120	ENOG4105Q9Y	Universal stress protein
FCL45_RS12135	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
FCL45_RS12145	ENOG4105C5H	ABC transporter
FCL45_RS12165	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FCL45_RS12185	ENOG4105D6U	Sodium Glutamate Symporter
FCL45_RS12195	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
FCL45_RS12200	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
FCL45_RS12205	ENOG4105C19	ABC transporter
FCL45_RS12210	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FCL45_RS12245	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
FCL45_RS12250	ENOG4107QZM	n-acetylglutamate synthase
FCL45_RS12255	ENOG4105W87	Cbs domain
FCL45_RS12270	ENOG4105DZS	Phenylacetate-CoA ligase
FCL45_RS12280	ENOG4105DZS	Phenylacetate-CoA ligase
FCL45_RS12290	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
FCL45_RS12295	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
FCL45_RS12300	ENOG4105E5N	succinylglutamate desuccinylase aspartoacylase
FCL45_RS12305	ENOG4105CJW	magnesium transporter
FCL45_RS12330	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL45_RS12340	ENOG4105RD8	TRAP dicarboxylate transporter
FCL45_RS12345	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
FCL45_RS12350	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
FCL45_RS12365	ENOG4105HDD	phospholipase
FCL45_RS12385	ENOG4105C8J	)-transporter
FCL45_RS12390	ENOG4105CBX	hi0933 family
FCL45_RS12400	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
FCL45_RS12405	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FCL45_RS12410	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
FCL45_RS12415	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
FCL45_RS12420	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
FCL45_RS12425	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FCL45_RS12430	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS12445	ENOG4107RZC	phospholipase d
FCL45_RS12450	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
FCL45_RS12460	ENOG4105CRK	lysyL-tRNA synthetase
FCL45_RS12465	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
FCL45_RS12480	ENOG4105HDK	L-asparaginase
FCL45_RS12485	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS12495	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FCL45_RS12500	ENOG4105CFG	Acts as a chaperone (By similarity)
FCL45_RS12520	ENOG4105CTD	carboxy-peptidase
FCL45_RS12535	ENOG4105K63	Thioredoxin
FCL45_RS12560	ENOG4105DFD	Na H antiporter
FCL45_RS12600	ENOG4105C26	Dehydrogenase
FCL45_RS12615	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
FCL45_RS12620	ENOG41063Z6	transcriptional regulator, lysR family
FCL45_RS12665	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FCL45_RS12705	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
FCL45_RS12710	ENOG4107XZQ	multidrug resistance protein
FCL45_RS12715	ENOG4105DEF	Extracellular solute-binding protein, family 5
FCL45_RS12720	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
FCL45_RS12725	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FCL45_RS12730	ENOG4105C3U	ABC transporter
FCL45_RS12735	ENOG4108JQ7	(ABC) transporter
FCL45_RS12740	ENOG4107SN7	NLP P60 protein
FCL45_RS12770	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
FCL45_RS12775	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
FCL45_RS12790	ENOG4108JQ1	Dehydrogenase
FCL45_RS12805	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
FCL45_RS12810	ENOG4108Z03	MAF-like protein
FCL45_RS12820	ENOG4105CDU	Replicative dna helicase
FCL45_RS12825	ENOG4105BZU	Histidine kinase
FCL45_RS12830	ENOG4108JIF	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
FCL45_RS12840	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
FCL45_RS12845	ENOG4108JQC	penicillin-binding protein 1A
FCL45_RS12850	ENOG4105CJ3	phosphate transporter
FCL45_RS12855	ENOG4107IX6	phosphate transport regulator
FCL45_RS12865	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
FCL45_RS12870	ENOG4105BZ8	glutamate synthase
FCL45_RS12885	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
FCL45_RS12890	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
FCL45_RS12895	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
FCL45_RS12905	ENOG4105D98	threonine synthase
FCL45_RS12910	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
FCL45_RS12915	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FCL45_RS12920	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
FCL45_RS12925	ENOG4105CHV	Transcription elongation factor NusA
FCL45_RS12935	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
FCL45_RS12940	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
FCL45_RS12950	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
FCL45_RS12955	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
FCL45_RS12960	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
FCL45_RS12965	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
FCL45_RS12970	ENOG4105Q2H	domain protein
FCL45_RS12975	ENOG410812S	Rna-binding protein
FCL45_RS12985	ENOG4105K4H	Nlp p60 protein
FCL45_RS12990	ENOG4108JQC	penicillin-binding protein 1A
FCL45_RS13000	ENOG4107QHF	type ii secretion system protein e
FCL45_RS13015	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
FCL45_RS13025	ENOG4105BZU	Histidine kinase
FCL45_RS13030	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
FCL45_RS13035	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
FCL45_RS13055	ENOG4107QKW	extracellular solute-binding protein family 1
FCL45_RS13060	ENOG4105EYA	deoxyribonuclease
FCL45_RS13080	ENOG4108J2R	molybdopterin oxidoreductase
FCL45_RS13085	ENOG4105F04	LysR family Transcriptional regulator
FCL45_RS13095	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
FCL45_RS13115	ENOG4105CEY	Amp-dependent synthetase and ligase
FCL45_RS13125	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
FCL45_RS13135	ENOG4105BZU	Histidine kinase
FCL45_RS13140	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FCL45_RS13160	ENOG4105EWK	phytoene
FCL45_RS13175	ENOG4105BZU	Histidine kinase
FCL45_RS13255	ENOG4107STQ	Multicopper oxidase
FCL45_RS13265	ENOG4105D9M	gamma-glutamylcysteine synthetase
FCL45_RS13290	ENOG4107QN2	dihydrolipoyl dehydrogenase
FCL45_RS13350	ENOG4105BZU	Histidine kinase
FCL45_RS13390	ENOG4105CKU	formyltetrahydrofolate synthetase
FCL45_RS13400	ENOG4105C72	UPF0176 protein
FCL45_RS13410	ENOG41076HS	cation diffusion facilitator family transporter
FCL45_RS13415	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
FCL45_RS13420	ENOG4107QR9	Iron-sulfur cluster binding protein
FCL45_RS13425	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
FCL45_RS13480	ENOG4107RIQ	Sulfate adenylate transferase
FCL45_RS13490	ENOG4107RJC	Iron-containing alcohol dehydrogenase
FCL45_RS13495	ENOG4105M3Z	response regulator
FCL45_RS13515	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
FCL45_RS13525	ENOG4105CP9	extracellular ligand-binding receptor
FCL45_RS13530	ENOG4105C8Q	Methyl-accepting chemotaxis
FCL45_RS13540	ENOG4105CGK	Exodeoxyribonuclease III
FCL45_RS13545	ENOG4105EAQ	(twin-arginine translocation) pathway signal
FCL45_RS13560	ENOG4105EW9	transcriptional regulator AsnC family
FCL45_RS13575	ENOG4107U32	Beta-lactamase domain protein
FCL45_RS13580	ENOG4105CKK	Glycosyl transferase, family 2
FCL45_RS13585	ENOG4105C9Q	fumarate hydratase class II
FCL45_RS13590	ENOG4105MAX	Superoxide reductase
FCL45_RS13615	ENOG4105CCU	oxidase (Subunit III)
FCL45_RS13625	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
FCL45_RS13630	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
FCL45_RS13645	ENOG4105VCQ	rubredoxin
FCL45_RS13655	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
FCL45_RS13660	ENOG4107TH8	cina domain protein
FCL45_RS13665	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FCL45_RS13670	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
FCL45_RS13675	ENOG4105CFP	Peptidase U32
FCL45_RS13680	ENOG4107GFK	fumarate
FCL45_RS13690	ENOG4105CHM	Aminotransferase
FCL45_RS13695	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FCL45_RS13705	ENOG4105D06	uba thif-type nad fad binding protein
FCL45_RS13725	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
FCL45_RS13765	ENOG4108I5D	sulfate abc transporter
FCL45_RS13770	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FCL45_RS13790	ENOG4108V1U	phospholipid-binding protein
FCL45_RS13795	ENOG4105C28	cystathionine
FCL45_RS13800	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
FCL45_RS13805	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL45_RS13820	ENOG4105EB3	Histidine kinase
FCL45_RS13855	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FCL45_RS13860	ENOG4105DVY	radical SAM domain protein
FCL45_RS13865	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
FCL45_RS13875	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
FCL45_RS13880	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
FCL45_RS13890	ENOG4105C8V	SAICAR synthetase
FCL45_RS13895	ENOG4105ECP	epimerase
FCL45_RS13900	ENOG4105VXR	cytoplasmic protein
FCL45_RS13905	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
FCL45_RS13935	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
FCL45_RS13940	ENOG4107RAN	Peptidase, M16
FCL45_RS13950	ENOG4105DVK	Precorrin-2 c20-methyltransferase
FCL45_RS13960	ENOG4105E0A	ABC, transporter
FCL45_RS13965	ENOG4105EHG	Permease protein
FCL45_RS13975	ENOG4105D07	Signal peptide peptidase, SppA
FCL45_RS13980	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
FCL45_RS13985	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
FCL45_RS14010	ENOG4105DB7	PHP domain protein
FCL45_RS14015	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS14020	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
FCL45_RS14025	ENOG4105W49	UPF0434 protein
FCL45_RS14055	ENOG4107QHF	type ii secretion system protein e
FCL45_RS14070	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
FCL45_RS14085	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
FCL45_RS14090	ENOG4108UJU	UPF0301 protein
FCL45_RS14100	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
FCL45_RS14105	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
FCL45_RS14110	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
FCL45_RS14115	ENOG4105CHW	UPF0052 protein
FCL45_RS14120	ENOG4108UNF	response regulator
FCL45_RS14130	ENOG4105CQ7	ATP-dependent helicase
FCL45_RS14135	ENOG4105C25	Primosomal protein n'
FCL45_RS14140	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
FCL45_RS14145	ENOG4107R1I	NAD-dependent malic enzyme
FCL45_RS14150	ENOG4105VEQ	Cold shock protein
FCL45_RS14155	ENOG4108J2P	Alpha beta hydrolase fold
FCL45_RS14160	ENOG410680H	amp-dependent synthetase and ligase
FCL45_RS14165	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
FCL45_RS14175	ENOG4105DX0	Hemolysin A
FCL45_RS14185	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
FCL45_RS14195	ENOG4105SG9	biopolymer transport protein, ExbD
FCL45_RS14200	ENOG4105E02	MotA TolQ exbB proton channel
FCL45_RS14205	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
FCL45_RS14210	ENOG4105CHR	reductase
FCL45_RS14225	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FCL45_RS14230	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FCL45_RS14250	ENOG4105CJR	Integral membrane protein (MviN
FCL45_RS14255	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FCL45_RS14260	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
FCL45_RS14265	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
FCL45_RS14275	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
FCL45_RS14280	ENOG4105CJW	magnesium transporter
FCL45_RS14285	ENOG4105C0H	protease
FCL45_RS14295	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
FCL45_RS14300	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
FCL45_RS14310	ENOG4105C8T	Leucyl-tRNA synthetase
FCL45_RS14315	ENOG4105CDU	Replicative dna helicase
FCL45_RS14320	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
FCL45_RS14330	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
FCL45_RS14335	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
FCL45_RS14340	ENOG4108IY2	MazG family
FCL45_RS14350	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
FCL45_RS14355	ENOG4105K46	50S ribosomal protein l27
FCL45_RS14360	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FCL45_RS14365	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
FCL45_RS14370	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
FCL45_RS14375	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
FCL45_RS14380	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
FCL45_RS14385	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
FCL45_RS14390	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FCL45_RS14395	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
FCL45_RS14410	ENOG4105C03	ribonuclease
FCL45_RS14440	ENOG4105KWG	Pfam:DUF1696
FCL45_RS14455	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FCL45_RS14485	ENOG4105DVC	DnaJ domain protein
FCL45_RS14495	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FCL45_RS14505	ENOG4105VEQ	Cold shock protein
FCL45_RS14510	ENOG4105K8N	protein family UPF0079, ATPase
FCL45_RS14530	ENOG4105ETX	regulatoR
FCL45_RS14535	ENOG4105BZU	Histidine kinase
FCL45_RS14540	ENOG4108P62	biosynthesis protein (CbiG)
FCL45_RS14545	ENOG4105E4R	Precorrin-3B C17-methyltransferase
FCL45_RS14560	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
FCL45_RS14565	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
FCL45_RS14570	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
FCL45_RS14575	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
FCL45_RS14580	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
FCL45_RS14585	ENOG41081F0	Precorrin-8x methylmutase
FCL45_RS14590	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
FCL45_RS14595	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FCL45_RS14605	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
FCL45_RS14610	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
FCL45_RS14620	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
FCL45_RS14625	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FCL45_RS14630	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
FCL45_RS14635	ENOG4105CP9	extracellular ligand-binding receptor
FCL45_RS14640	ENOG4105C32	Amino acid ABC transporter (Permease)
FCL45_RS14645	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
FCL45_RS14650	ENOG4105C0Z	ABC transporter
FCL45_RS14655	ENOG4108IV0	ABC, transporter
FCL45_RS14665	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FCL45_RS14670	ENOG4105C98	muts2 protein
FCL45_RS14675	ENOG4105C34	Pseudouridine synthase
FCL45_RS14680	ENOG4107QQG	Dehydrogenase
FCL45_RS14695	ENOG4105C0P	Mg chelatase subunit ChlI
FCL45_RS14710	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
FCL45_RS14715	ENOG4107YWA	deoxycytidylate deaminase
FCL45_RS14745	ENOG4108JJB	ABC transporter
FCL45_RS14770	ENOG4108R4U	Hnh endonuclease
FCL45_RS14780	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FCL45_RS14845	ENOG4108I5C	dEAD DEAH box helicase
FCL45_RS14855	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
FCL45_RS14860	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
FCL45_RS14875	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
FCL45_RS14880	ENOG4105DF5	DNA topoisomerase IV, subunit A
FCL45_RS14885	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FCL45_RS14900	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
FCL45_RS14905	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
FCL45_RS14915	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
FCL45_RS14920	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
FCL45_RS14930	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
FCL45_RS14940	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
FCL45_RS14945	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
FCL45_RS14950	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FCL45_RS14955	ENOG4108JPZ	Monovalent cation H antiporter subunit D
FCL45_RS14970	ENOG4108JPZ	Monovalent cation H antiporter subunit D
FCL45_RS14985	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS14995	ENOG4108UH6	UPF0754 membrane protein
FCL45_RS15000	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
FCL45_RS15020	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
FCL45_RS15045	ENOG4105CD8	aminopeptidase N
FCL45_RS15050	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
FCL45_RS15055	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
FCL45_RS15065	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL45_RS15070	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
FCL45_RS15075	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
FCL45_RS15085	ENOG4105CQZ	Histidine kinase
FCL45_RS15090	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
FCL45_RS15100	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
FCL45_RS15105	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
FCL45_RS15115	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
FCL45_RS15120	ENOG4105K70	DNA-binding protein
FCL45_RS15130	ENOG4105CQC	Prephenate dehydratase
FCL45_RS15135	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FCL45_RS15145	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
FCL45_RS15150	ENOG4107QW4	alcohol dehydrogenase
FCL45_RS15160	ENOG410848D	S4 domain protein YaaA
FCL45_RS15170	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
FCL45_RS15190	ENOG4107QY8	reductase
FCL45_RS15195	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
FCL45_RS15200	ENOG4105C5H	ABC transporter
FCL45_RS15210	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FCL45_RS15215	ENOG4105C12	Phosphoribosylglycinamide synthetase
FCL45_RS15220	ENOG4107Z3H	Transcriptional regulator, TetR family
FCL45_RS15225	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
FCL45_RS15240	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FCL45_RS15245	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
FCL45_RS15265	ENOG4105C26	Dehydrogenase
FCL45_RS15280	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL45_RS15300	ENOG4105EJQ	L-serine dehydratase
FCL45_RS15310	ENOG4105EB3	Histidine kinase
FCL45_RS15320	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS15330	ENOG410804T	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
FCL45_RS15335	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
FCL45_RS15345	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FCL45_RS15355	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
FCL45_RS15365	ENOG4107TEJ	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
FCL45_RS15370	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
FCL45_RS15375	ENOG4105CAK	Cell division ATP-binding protein ftsE
FCL45_RS15380	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
FCL45_RS15390	ENOG4105CN1	protease
FCL45_RS15395	ENOG4105VTS	DnaJ-like, subfamily C
FCL45_RS15405	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
FCL45_RS15410	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
FCL45_RS15430	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
FCL45_RS15435	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
FCL45_RS15445	ENOG4105EWC	Purine nucleoside phosphorylase
FCL45_RS15465	ENOG4105VB9	50S ribosomal protein l28
FCL45_RS15470	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
FCL45_RS15485	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
FCL45_RS15490	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
FCL45_RS15495	ENOG410812K	response regulator receiver protein
FCL45_RS15510	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FCL45_RS15515	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FCL45_RS15520	ENOG41084BP	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
FCL45_RS15525	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
FCL45_RS15530	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
FCL45_RS15535	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
FCL45_RS15570	ENOG4105D49	3-dehydroquinate synthase
FCL45_RS15575	ENOG4107RIQ	Sulfate adenylate transferase
FCL45_RS15625	ENOG4105BZU	Histidine kinase
FCL45_RS15670	ENOG4105CMM	transposase
FCL45_RS15690	ENOG4105DA5	(ABC) transporter
FCL45_RS15740	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
FCL45_RS15750	ENOG4105C8B	TIGR00159 family
FCL45_RS15760	ENOG4108RCM	Nitroreductase
FCL45_RS15775	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS15785	ENOG4105C8N	cysteinyl-tRNA synthetase
FCL45_RS15790	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
FCL45_RS15810	ENOG4105C3R	Methionine synthase
FCL45_RS15825	ENOG4105DFU	Cell wall formation (By similarity)
FCL45_RS15840	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
FCL45_RS15845	ENOG4105EM7	Selenocysteine-specific translation elongation factor
FCL45_RS15850	ENOG4105C5X	domain protein
FCL45_RS15855	ENOG4105D1F	ATP-binding protein
FCL45_RS15860	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FCL45_RS15865	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FCL45_RS15870	ENOG4105CHM	Aminotransferase
FCL45_RS15880	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
FCL45_RS15885	ENOG4105EHM	Aminoglycoside phosphotransferase
FCL45_RS15890	ENOG4107Z36	nucleotidyl transferase
FCL45_RS15895	ENOG4105GYT	Protein of unknown function (DUF1009)
FCL45_RS15900	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FCL45_RS15905	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
FCL45_RS15910	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FCL45_RS15915	ENOG4105EHZ	conserved protein UCP016719
FCL45_RS15920	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
FCL45_RS15925	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
FCL45_RS15955	ENOG4105HHA	aminodeoxychorismate lyase
FCL45_RS15960	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
FCL45_RS15965	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
FCL45_RS15985	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
FCL45_RS15990	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
FCL45_RS16000	ENOG4105DQU	oxidoreductase, subunit beta
FCL45_RS16005	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
FCL45_RS16015	ENOG4105DRR	Transcriptional regulator, GntR family
FCL45_RS16020	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
FCL45_RS16030	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
FCL45_RS16035	ENOG4105K5B	UPF0225 protein
FCL45_RS16040	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
FCL45_RS16045	ENOG4105HFZ	Membrane
FCL45_RS16050	ENOG4105D3Q	Sugar transferase
FCL45_RS16055	ENOG4105CND	Glycosyl transferase, family 2
FCL45_RS16070	ENOG4105CKK	Glycosyl transferase, family 2
FCL45_RS16090	ENOG4105K64	Glycosyl transferase, family 2
FCL45_RS16100	ENOG4105EY8	ABC transporter
FCL45_RS16145	ENOG4108UW5	maltose o-acetyltransferase
FCL45_RS16160	ENOG4105CKK	Glycosyl transferase, family 2
FCL45_RS16165	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
FCL45_RS16175	ENOG4105BZ1	(ABC) transporter
FCL45_RS16185	ENOG4105BZU	Histidine kinase
FCL45_RS16195	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
FCL45_RS16205	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
FCL45_RS16210	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
FCL45_RS16220	ENOG4105KK6	nuclease
FCL45_RS16225	ENOG4105EYW	Ion transport protein
FCL45_RS16290	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
FCL45_RS16295	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
FCL45_RS16300	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
FCL45_RS16305	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
FCL45_RS16315	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
FCL45_RS16320	ENOG4105C9A	Phoh family
FCL45_RS16325	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
FCL45_RS16335	ENOG4105DFP	Integrase
FCL45_RS16440	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FCL45_RS16450	ENOG4105RWS	endonuclease I
FCL45_RS16565	ENOG4105K6T	rare lipoprotein A
FCL45_RS16570	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
FCL45_RS16575	ENOG4105DK0	Indole-3-glycerol phosphate synthase
FCL45_RS16580	ENOG4107QYG	anthranilate phosphoribosyltransferase
FCL45_RS16585	ENOG4105DDQ	anthranilate synthase
FCL45_RS16595	ENOG4108317	Binds directly to 16S ribosomal RNA (By similarity)
FCL45_RS16605	ENOG4105CFP	Peptidase U32
FCL45_RS16610	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
FCL45_RS16615	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
FCL45_RS16620	ENOG4105DC1	bifunctional purine biosynthesis protein purh
FCL45_RS16625	ENOG4105VEJ	Heat shock protein
FCL45_RS16630	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
FCL45_RS16640	ENOG41061AI	Protein of unknown function (DUF2905)
FCL45_RS16645	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FCL45_RS16650	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
FCL45_RS16665	ENOG4105C5I	Dehydrogenase
FCL45_RS16675	ENOG4107TT5	NLP P60 protein
FCL45_RS16680	ENOG4105N42	UPF0307 protein
FCL45_RS16685	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FCL45_RS16695	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
FCL45_RS16700	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
FCL45_RS16715	ENOG4105BZU	Histidine kinase
FCL45_RS16720	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
FCL45_RS16725	ENOG4108JQ5	ABC transporter
FCL45_RS16730	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
FCL45_RS16735	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
FCL45_RS16755	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
FCL45_RS16760	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
FCL45_RS16765	ENOG4105CZX	twitching motility protein
FCL45_RS16770	ENOG4108URH	decarboxylase
FCL45_RS16780	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
FCL45_RS16810	ENOG4105BZG	amino acid carrier protein
FCL45_RS16815	ENOG4108JEH	abc transporter atp-binding protein
FCL45_RS16820	ENOG4105E89	ABC transporter
FCL45_RS16825	ENOG4105DSP	amino acid AbC transporter
FCL45_RS16865	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FCL45_RS16870	ENOG4105M3Z	response regulator
FCL45_RS16890	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FCL45_RS16915	ENOG4105ETE	Transcriptional regulator (LacI family
FCL45_RS16920	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
FCL45_RS16930	ENOG4105CTX	dehydratase
FCL45_RS16935	ENOG4105VP7	SAF domain protein
FCL45_RS16945	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
FCL45_RS16950	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL45_RS16955	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
FCL45_RS16960	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
FCL45_RS16965	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
FCL45_RS16970	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
FCL45_RS16975	ENOG4105CTX	dehydratase
FCL45_RS16980	ENOG4105VP7	SAF domain protein
FCL45_RS16990	ENOG4108JUA	Transcriptional regulator
FCL45_RS16995	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
FCL45_RS17020	ENOG4105DAN	ATP-dependent protease
FCL45_RS17030	ENOG4105CHR	reductase
FCL45_RS17035	ENOG4105EWT	decarboxylase family
FCL45_RS17040	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
FCL45_RS17050	ENOG4107QY8	reductase
FCL45_RS17055	ENOG4107SFQ	iron-sulfur binding
FCL45_RS17060	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
FCL45_RS17075	ENOG4108UPT	UPF0178 protein
FCL45_RS17090	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
FCL45_RS17115	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
FCL45_RS17120	ENOG4105EYW	Ion transport protein
FCL45_RS17130	ENOG4105D0C	transport protein
FCL45_RS17160	ENOG4105CCS	Glutamate formiminotransferase
FCL45_RS17165	ENOG4105CI2	imidazolone-5-propionate hydrolase
FCL45_RS17170	ENOG4105CGP	Urocanate hydratase
FCL45_RS17175	ENOG4105C84	Histidine ammonia-lyase
FCL45_RS17180	ENOG4105CZE	histidine utilization repressor
FCL45_RS17190	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
FCL45_RS17230	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
FCL45_RS17235	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS17255	ENOG4107SVN	transposase
FCL45_RS17260	ENOG4108IPJ	Membrane
FCL45_RS17265	ENOG4105VRT	cytoplasmic protein
FCL45_RS17280	ENOG4108Z4V	iron-sulfur cluster assembly
FCL45_RS17290	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
FCL45_RS17335	ENOG4105EWK	phytoene
FCL45_RS17370	ENOG4105BZU	Histidine kinase
FCL45_RS17375	ENOG4105DF6	Fe-S oxidoreductase
FCL45_RS17415	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
FCL45_RS17420	ENOG41080XS	Cobyrinic acid ac-diamide synthase
FCL45_RS17430	ENOG4107VP5	methyltetrahydrofolate corrinoid iron-sulfur protein methyltransferase
FCL45_RS17435	ENOG4105EYX	Acetyl-CoA decarbonylase synthase complex subunit gamma
FCL45_RS17440	ENOG4105E8X	CO dehydrogenase acetyl-CoA synthase complex beta subunit
FCL45_RS17445	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
FCL45_RS17450	ENOG4106HYN	CO dehydrogenase acetyl-CoA synthase delta subunit
FCL45_RS17465	ENOG4108RAC	Rubrerythrin
FCL45_RS17490	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
FCL45_RS17495	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
FCL45_RS17505	ENOG4107QN1	sodium solute
FCL45_RS17520	ENOG4105CJW	magnesium transporter
FCL45_RS17525	ENOG4108URH	decarboxylase
FCL45_RS17610	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FCL45_RS17615	ENOG4105CYC	Transferase
FCL45_RS17630	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
FCL45_RS17635	ENOG4105C1G	acyl-Coa dehydrogenase
FCL45_RS17640	ENOG4105E39	Enoyl-CoA hydratase
FCL45_RS17655	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
FCL45_RS17660	ENOG4105CHU	acetyl-coa acetyltransferase
FCL45_RS17665	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FCL45_RS17670	ENOG4105C1G	acyl-Coa dehydrogenase
FCL45_RS17675	ENOG4107Z3H	Transcriptional regulator, TetR family
FCL45_RS17680	ENOG4105D5P	Methylmalonyl-coA mutase
FCL45_RS17695	ENOG4108JQ9	ABC transporter
FCL45_RS17750	ENOG4108IJF	Heavy metal efflux pump, CzcA
FCL45_RS17760	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS17770	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
FCL45_RS17780	ENOG4108VCT	Sulfite exporter TauE/SafE
FCL45_RS17795	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
FCL45_RS17800	ENOG4107QY8	reductase
FCL45_RS17810	ENOG4105BZU	Histidine kinase
FCL45_RS17820	ENOG4105K56	Transcriptional regulator
FCL45_RS17825	ENOG4105EGS	Mechanosensitive ion channel
FCL45_RS17830	ENOG4105DGU	Histone deacetylase
FCL45_RS17845	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FCL45_RS17850	ENOG4105DGU	Histone deacetylase
FCL45_RS17865	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
FCL45_RS17870	ENOG4105D9Q	decarboxylase (Beta subunit)
FCL45_RS17880	ENOG4108ZVT	methylmalonyl-coA epimerase
FCL45_RS17885	ENOG4105D5P	Methylmalonyl-coA mutase
FCL45_RS17890	ENOG4105DJT	lAO AO transport system ATPase
FCL45_RS17895	ENOG4105DSF	transport protein
FCL45_RS17930	ENOG4108ZF3	Phosphatase
FCL45_RS17940	ENOG4105D9P	serine threonine protein kinase
FCL45_RS17945	ENOG4105BZU	Histidine kinase
FCL45_RS17960	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FCL45_RS18050	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FCL45_RS18070	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FCL45_RS18085	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
FCL45_RS18090	ENOG4108R5S	membrane
FCL45_RS18120	ENOG4105DTQ	mandelate racemase muconate lactonizing
FCL45_RS18130	ENOG4105E4C	Lytic transglycosylase catalytic
FCL45_RS18135	ENOG4105IPI	Membrane
FCL45_RS18150	ENOG4105EFX	secretion protein, HlyD family
FCL45_RS18160	ENOG4105C7B	Threonine dehydratase
FCL45_RS18165	ENOG4105EKE	dihydroorotase
FCL45_RS18170	ENOG4108Z0R	Transferase
FCL45_RS18175	ENOG4107QSA	Oxaloacetate decarboxylase
FCL45_RS18195	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
FCL45_RS18200	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
FCL45_RS18205	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FCL45_RS18215	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS18220	ENOG4106HK8	GPR1 FUN34 yaaH family protein
FCL45_RS18225	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FCL45_RS18230	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FCL45_RS18260	ENOG4105C1G	acyl-Coa dehydrogenase
FCL45_RS18280	ENOG4105CA9	Pyruvate kinase
FCL45_RS18285	ENOG4108ZJT	translation initiation factor, Sui1
FCL45_RS18290	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
FCL45_RS18315	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
FCL45_RS18320	ENOG4105CQB	FAD linked oxidase domain protein
FCL45_RS18325	ENOG4107QYX	exodeoxyribonuclease v alpha
FCL45_RS18330	ENOG4107QKA	exodeoxyribonuclease V beta
FCL45_RS18335	ENOG4105DSY	exodeoxyribonuclease V, gamma
FCL45_RS18350	ENOG41081QV	Universal stress protein
FCL45_RS18365	ENOG4108IQE	Amp-dependent synthetase and ligase
FCL45_RS18370	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
FCL45_RS18380	ENOG4105C5S	asparaginyl-tRNA synthetase
FCL45_RS18400	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
FCL45_RS18410	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
FCL45_RS18415	ENOG4108UJD	30S ribosomal protein S9
FCL45_RS18420	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
FCL45_RS18425	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
FCL45_RS18430	ENOG4108M0I	Transcriptional regulator
FCL45_RS18435	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FCL45_RS18440	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FCL45_RS18445	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FCL45_RS18450	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FCL45_RS18455	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
FCL45_RS18465	ENOG4107YX3	NADH dehydrogenase subunit j
FCL45_RS18470	ENOG4107EJQ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FCL45_RS18475	ENOG4108JPZ	Monovalent cation H antiporter subunit D
FCL45_RS18485	ENOG4108JPZ	Monovalent cation H antiporter subunit D
FCL45_RS18490	ENOG4105C8S	subunit m
FCL45_RS18495	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FCL45_RS18500	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
FCL45_RS18555	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
FCL45_RS18560	ENOG4105D6A	Electron transport complex
FCL45_RS18565	ENOG4108UQQ	Electron transport complex
FCL45_RS18570	ENOG4105DZB	Electron transport complex
FCL45_RS18575	ENOG4105DGN	Electron transport complex
FCL45_RS18580	ENOG4105BZ8	glutamate synthase
FCL45_RS18600	ENOG4105KNY	Microcompartments protein
FCL45_RS18605	ENOG4105C0A	alcohol dehydrogenase
FCL45_RS18610	ENOG4105C6N	Formate acetyltransferase
FCL45_RS18615	ENOG4105F1A	Pyruvate formate-lyase
FCL45_RS18620	ENOG4105KNY	Microcompartments protein
FCL45_RS18625	ENOG4105C0A	alcohol dehydrogenase
FCL45_RS18630	ENOG4105KNY	Microcompartments protein
FCL45_RS18635	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
FCL45_RS18640	ENOG4107RWI	ethanolamine utilization protein eutJ
FCL45_RS18650	ENOG4105WVM	ethanolamine utilization protein EutN carboxysome structural protein Ccml
FCL45_RS18665	ENOG4105KNY	Microcompartments protein
FCL45_RS18685	ENOG4105M3W	utilization protein
FCL45_RS18690	ENOG4105KTW	ethanolamine utilization protein
FCL45_RS18695	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
FCL45_RS18700	ENOG4105E0C	molybdate abc transporter
FCL45_RS18705	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
FCL45_RS18710	ENOG4105F4R	Transcriptional regulator mode
FCL45_RS18730	ENOG4107QX8	SPFH domain, Band 7 family protein
FCL45_RS18735	ENOG4108IAB	Phoh family
FCL45_RS18740	ENOG4105CTQ	phosphohexokinase
FCL45_RS18755	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
FCL45_RS18765	ENOG4105DPN	Oligoendopeptidase f
FCL45_RS18775	ENOG4108Z6B	deaminase
FCL45_RS18790	ENOG4105C6E	dna polymerase iii
FCL45_RS18795	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
FCL45_RS18800	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
FCL45_RS18810	ENOG4105C22	threonyL-tRNA synthetase
FCL45_RS18815	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
FCL45_RS18820	ENOG4105VJV	50s ribosomal protein L35
FCL45_RS18825	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
FCL45_RS18830	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
FCL45_RS18835	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
FCL45_RS18840	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
FCL45_RS18890	ENOG4105CY3	ABC transporter, permease
FCL45_RS18905	ENOG4105E0X	reductase
FCL45_RS18915	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
FCL45_RS18945	ENOG4105BZU	Histidine kinase
FCL45_RS18965	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
FCL45_RS18970	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
FCL45_RS18975	ENOG4105CBT	Fructose-1,6-bisphosphatase
FCL45_RS18980	ENOG4105E3S	small subunit
FCL45_RS18985	ENOG4105DPX	Hydrogenase, large subunit
FCL45_RS18995	ENOG4105BZU	Histidine kinase
FCL45_RS19000	ENOG4107RZH	Nitrite and sulphite reductase 4Fe-4S region
FCL45_RS19005	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
FCL45_RS19015	ENOG4105C0B	DNA polymerase III (alpha subunit)
FCL45_RS19030	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
FCL45_RS19035	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
FCL45_RS19040	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FCL45_RS19045	ENOG41084YM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FCL45_RS19055	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
FCL45_RS19080	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
FCL45_RS19090	ENOG41082IR	Excinuclease ABC C subunit domain protein
FCL45_RS19095	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS19100	ENOG4105BZU	Histidine kinase
FCL45_RS19130	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
FCL45_RS19140	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
FCL45_RS19145	ENOG41082DI	50s ribosomal protein l31
FCL45_RS19150	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
FCL45_RS19155	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
FCL45_RS19160	ENOG4105C34	Pseudouridine synthase
FCL45_RS19165	ENOG4108VJ1	Transcriptional regulator (CarD family
FCL45_RS19170	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
FCL45_RS19175	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
FCL45_RS19180	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FCL45_RS19190	ENOG4107Z7S	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
FCL45_RS19205	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
FCL45_RS19210	ENOG4105CX6	glutaminyL-tRNA synthetase
FCL45_RS19225	ENOG4105CE1	Ferrous iron transport protein b
FCL45_RS19235	ENOG4105EMN	RNA polymerase sigma factor
FCL45_RS19250	ENOG4105JKW	Valine--pyruvate aminotransferase
FCL45_RS19260	ENOG4105CVJ	phosphoglycerate mutase
FCL45_RS19265	ENOG4107QJE	Chromosome Partitioning Protein
FCL45_RS19275	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
FCL45_RS19290	ENOG4105CSR	polyphosphate kinase 2
FCL45_RS19295	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
FCL45_RS19305	ENOG4105C75	arginyL-tRNA synthetase
FCL45_RS19310	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
FCL45_RS19330	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
FCL45_RS19340	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
FCL45_RS19365	ENOG4105CNW	domain protein
FCL45_RS19375	ENOG4105WZW	rhodanese family
FCL45_RS19380	ENOG4107TPS	domain protein
FCL45_RS19390	ENOG4105KY8	Rubrerythrin
FCL45_RS19395	ENOG4105DXX	methyltransferase
FCL45_RS19400	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
FCL45_RS19405	ENOG4107RZH	Nitrite and sulphite reductase 4Fe-4S region
FCL45_RS19420	ENOG4108RH0	Crea protein
FCL45_RS19450	ENOG4107SVN	transposase
FCL45_RS19455	ENOG4107SVN	transposase
FCL45_RS19485	ENOG4105ESV	Glycosyl transferase, family 4
FCL45_RS19500	ENOG4105D3Q	Sugar transferase
FCL45_RS19510	ENOG4105D3Q	Sugar transferase
FCL45_RS19520	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
FCL45_RS19545	ENOG4108UW5	maltose o-acetyltransferase
FCL45_RS19580	ENOG4105K64	Glycosyl transferase, family 2
FCL45_RS19590	ENOG4108UT6	Transferase hexapeptide repeat containing protein
FCL45_RS19600	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
FCL45_RS19605	ENOG4107QQG	Dehydrogenase
FCL45_RS19610	ENOG4105CY0	Metallo-Beta-Lactamase
FCL45_RS19625	ENOG4107QQG	Dehydrogenase
FCL45_RS19645	ENOG4105CAQ	asparagine synthetase
FCL45_RS19680	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
FCL45_RS19685	ENOG4105C7K	acetolactate synthase
FCL45_RS19690	ENOG4108ZP8	Acetolactate synthase small subunit
FCL45_RS19695	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
FCL45_RS19700	ENOG4107SVN	transposase
FCL45_RS19710	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
FCL45_RS19715	ENOG4106H78	methyltransferase
FCL45_RS19720	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
FCL45_RS19740	ENOG4105CXV	gliding motility protein
FCL45_RS19750	ENOG4105F8V	Hydrolase, tatD family
FCL45_RS19755	ENOG4105DFA	alanine racemase domain protein
FCL45_RS19760	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
FCL45_RS19785	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
FCL45_RS19790	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
FCL45_RS19795	ENOG4108YZG	isomerase
FCL45_RS19800	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FCL45_RS19805	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FCL45_RS19810	ENOG4105CHR	reductase
FCL45_RS19815	ENOG4105C10	Electron transfer flavoprotein
FCL45_RS19820	ENOG4105BZJ	Electron transfer flavoprotein
FCL45_RS19830	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
FCL45_RS19835	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
FCL45_RS19840	ENOG41085D1	50S ribosomal protein L32
FCL45_RS19865	ENOG4107PE3	Mammalian cell entry related domain protein
FCL45_RS19870	ENOG4105DHJ	ABC, transporter
FCL45_RS19875	ENOG4105CY3	ABC transporter, permease
FCL45_RS19880	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
FCL45_RS19885	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
FCL45_RS19890	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
FCL45_RS19905	ENOG4105FAE	von Willebrand factor, type A
FCL45_RS19910	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
FCL45_RS19925	ENOG4105K5M	30s ribosomal protein S16
FCL45_RS19930	ENOG4105VB6	UPF0109 protein
FCL45_RS19935	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
FCL45_RS19940	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
FCL45_RS19945	ENOG4108WTY	tRNA (Guanine-N(1)-)-methyltransferase
FCL45_RS19950	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
FCL45_RS19955	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FCL45_RS19960	ENOG41082RQ	UPF0102 protein
FCL45_RS19965	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
FCL45_RS19970	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
FCL45_RS19990	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FCL45_RS20000	ENOG4107RA4	Glycosyl transferase (Group 1
FCL45_RS20030	ENOG4107RH8	nuclease SbcCD subunit D
FCL45_RS20035	ENOG4105EYH	Exonuclease
FCL45_RS20040	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
FCL45_RS20050	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
FCL45_RS20055	ENOG4105VYW	UPF0251 protein
FCL45_RS20070	ENOG4105ES5	Histidine kinase
FCL45_RS20075	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS20080	ENOG4105D52	delta-aminolevulinic acid dehydratase
FCL45_RS20090	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
FCL45_RS20100	ENOG4105EV9	Alpha Beta Hydrolase
FCL45_RS20105	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
FCL45_RS20135	ENOG4107KET	secretion protein, HlyD family
FCL45_RS20160	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
FCL45_RS20220	ENOG4105EN6	Membrane
FCL45_RS20295	ENOG4108RW8	Universal stress protein F
FCL45_RS20355	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
FCL45_RS20360	ENOG4105C4R	Atp-dependent dna helicase
FCL45_RS20395	ENOG4105CRQ	synthase (Component I)
FCL45_RS20420	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
FCL45_RS20430	ENOG41083J0	(ABC) transporter
FCL45_RS20435	ENOG4105BZU	Histidine kinase
FCL45_RS20440	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FCL45_RS20445	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
FCL45_RS20450	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
FCL45_RS20455	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
FCL45_RS20460	ENOG4105DFU	Cell wall formation (By similarity)
FCL45_RS20465	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
FCL45_RS20470	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
FCL45_RS20475	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
FCL45_RS20480	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
FCL45_RS20495	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
FCL45_RS20500	ENOG4108V6E	Cell division protein mraZ
FCL45_RS20505	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
FCL45_RS20510	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
FCL45_RS20515	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
FCL45_RS20520	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
FCL45_RS20525	ENOG4105CDY	transcriptional regulatory protein
FCL45_RS20530	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
FCL45_RS20540	ENOG4105CUY	Mechanosensitive ion channel
FCL45_RS20550	ENOG4108DBC	nitroreductase
FCL45_RS20555	ENOG4105RK9	auxin efflux carrier
FCL45_RS20565	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
FCL45_RS20615	ENOG41088T4	Helicase IV
FCL45_RS20645	ENOG4105RWS	endonuclease I
FCL45_RS20705	ENOG4107QYX	exodeoxyribonuclease v alpha
FCL45_RS20710	ENOG4108P8R	
FCL45_RS20720	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FCL45_RS20725	ENOG4105D1H	recombination factor protein RarA
FCL45_RS20735	ENOG4105CQB	FAD linked oxidase domain protein
FCL45_RS20760	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
FCL45_RS20765	ENOG4107R37	Glutamate dehydrogenase
FCL45_RS20780	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FCL45_RS20810	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
FCL45_RS20815	ENOG4105E63	Pfam:DUF178
FCL45_RS20825	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
FCL45_RS20835	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
FCL45_RS20850	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
FCL45_RS20855	ENOG4105C2N	RNA methyltransferase TrmH family group 3
FCL45_RS20860	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
FCL45_RS20865	ENOG4105KC4	UPF0296 protein
FCL45_RS20870	ENOG4105DSJ	YicC domain protein
FCL45_RS20880	ENOG4105KCK	Peptidoglycan-associated lipoprotein
FCL45_RS20885	ENOG4107R76	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
FCL45_RS20900	ENOG4105G5W	regulator Fur family
FCL45_RS20905	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
FCL45_RS20910	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
FCL45_RS20930	ENOG4108Z4K	mutator MutT protein
FCL45_RS20960	ENOG4107S2Z	UPF0761 membrane protein
FCL45_RS20965	ENOG4105BZU	Histidine kinase
FCL45_RS20970	ENOG4105BZU	Histidine kinase
FCL45_RS20975	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FCL45_RS20980	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
FCL45_RS20985	ENOG4105C8U	phosphate abc transporter
FCL45_RS21000	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
FCL45_RS21005	ENOG4108M19	cytochrome C
FCL45_RS21010	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS21015	ENOG4108ZP8	Acetolactate synthase small subunit
FCL45_RS21065	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
FCL45_RS21075	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
FCL45_RS21080	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
FCL45_RS21085	ENOG4105BZ4	penicillin-binding protein
FCL45_RS21095	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
FCL45_RS21100	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FCL45_RS21105	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FCL45_RS21110	ENOG4105C8S	subunit m
FCL45_RS21115	ENOG4105D65	subunit l
FCL45_RS21130	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FCL45_RS21135	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
FCL45_RS21140	ENOG4108IEH	NADH dehydrogenase subunit g
FCL45_RS21155	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FCL45_RS21160	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FCL45_RS21165	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FCL45_RS21170	ENOG4105CZK	Aspartate kinase
FCL45_RS21175	ENOG4105CDV	Ompa motb domain protein
FCL45_RS21180	ENOG4105CVE	Lytic murein transglycosylase
FCL45_RS21225	ENOG4108SAU	DNA-binding protein H-ns
FCL45_RS21240	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FCL45_RS21255	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS21260	ENOG4105ETX	regulatoR
FCL45_RS21265	ENOG410812K	response regulator receiver protein
FCL45_RS21270	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
FCL45_RS21290	ENOG4105D0M	Protease HtpX homolog
FCL45_RS21295	ENOG4105EPR	degv family
FCL45_RS21315	ENOG4108FN7	Aldo keto reductase
FCL45_RS21320	ENOG4105C8M	UPF0272 protein
FCL45_RS21350	ENOG4105EQR	Transposase IS116 IS110 IS902
FCL45_RS21375	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
FCL45_RS21390	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FCL45_RS21405	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
FCL45_RS21435	ENOG4105D06	uba thif-type nad fad binding protein
FCL45_RS21440	ENOG4105D41	biosynthesis protein thiH
FCL45_RS21445	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
FCL45_RS21450	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
FCL45_RS21465	ENOG4105Y3U	Transglycosylase-associated protein
FCL45_RS21485	ENOG4105KVH	Transcriptional regulator
FCL45_RS21490	ENOG4107QY8	reductase
FCL45_RS21495	ENOG4105ECQ	AraC Family Transcriptional Regulator
FCL45_RS21505	ENOG4105ECK	Fatty Acid Desaturase
FCL45_RS21535	ENOG4105F8D	glycoside hydrolase family 4
FCL45_RS21540	ENOG41071MT	Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane
FCL45_RS21545	ENOG4105C2J	ABC transporter
FCL45_RS21555	ENOG4105CPN	adenine deaminase
FCL45_RS21560	ENOG4105CPN	adenine deaminase
FCL45_RS21660	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
FCL45_RS21670	ENOG4105WMR	Protein CrcB homolog
FCL45_RS21685	ENOG4108V1T	peptidylprolyl cis-trans isomerase
FCL45_RS21695	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
FCL45_RS21700	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
FCL45_RS21705	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
FCL45_RS21710	ENOG41072GX	Peptidase M22 Glycoprotease
FCL45_RS21715	ENOG4105DZP	Membrane-associated zinc metalloprotease
FCL45_RS21720	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
FCL45_RS21725	ENOG4105KNE	Phosphatidate cytidylyltransferase
FCL45_RS21730	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
FCL45_RS21735	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
FCL45_RS21740	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
FCL45_RS21745	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
FCL45_RS21750	ENOG4105CE9	30S ribosomal protein S2
FCL45_RS21760	ENOG4108ZT0	50S ribosomal protein l17
FCL45_RS21765	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FCL45_RS21770	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
FCL45_RS21775	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
FCL45_RS21780	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FCL45_RS21785	ENOG41086F9	50S ribosomal protein L36
FCL45_RS21790	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
FCL45_RS21800	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
FCL45_RS21805	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
FCL45_RS21810	ENOG4105VPB	50S ribosomal protein L30
FCL45_RS21815	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
FCL45_RS21820	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
FCL45_RS21835	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
FCL45_RS21840	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FCL45_RS21845	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
FCL45_RS21850	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
FCL45_RS21855	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
FCL45_RS21860	ENOG41082SA	50s ribosomal protein l29
FCL45_RS21865	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
FCL45_RS21870	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
FCL45_RS21875	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
FCL45_RS21880	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
FCL45_RS21885	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FCL45_RS21890	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
FCL45_RS21895	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
FCL45_RS21900	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
FCL45_RS21905	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
FCL45_RS21910	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
FCL45_RS21915	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FCL45_RS21920	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
FCL45_RS21925	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
FCL45_RS21930	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FCL45_RS21935	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FCL45_RS21940	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
FCL45_RS21945	ENOG4108VZM	50s ribosomal protein L10
FCL45_RS21950	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
FCL45_RS21955	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
FCL45_RS21960	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
FCL45_RS21975	ENOG41084ED	50S ribosomal protein L33
FCL45_RS21980	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
FCL45_RS22015	ENOG4105EWK	phytoene
FCL45_RS22030	ENOG4105CNU	cell division protein FtsK
FCL45_RS22035	ENOG4105M7K	Involved in the transcription termination process (By similarity)
FCL45_RS22040	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
FCL45_RS22045	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
FCL45_RS22090	ENOG4107RIZ	hflk protein
FCL45_RS22095	ENOG4105EPW	hflc protein
FCL45_RS22105	ENOG4105BZN	citrate synthase
FCL45_RS22110	ENOG4105C2M	dna polymerase I
FCL45_RS22120	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
FCL45_RS22125	ENOG4105CNI	cell division protein FtsW
FCL45_RS22130	ENOG4105CJN	penicillin-binding protein
FCL45_RS22160	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
FCL45_RS22170	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
FCL45_RS22175	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
FCL45_RS22185	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
FCL45_RS22200	ENOG4105CTQ	phosphohexokinase
FCL45_RS22215	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FCL45_RS22280	ENOG4105BZ1	(ABC) transporter
FCL45_RS22285	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
FCL45_RS22290	ENOG4105DC1	bifunctional purine biosynthesis protein purh
FCL45_RS22300	ENOG41080IJ	Diacylglycerol kinase
FCL45_RS22310	ENOG4105EAH	synthase
FCL45_RS22315	ENOG4105DVT	helicase
FCL45_RS22320	ENOG4105BZU	Histidine kinase
FCL45_RS22350	ENOG4107TYR	Glycosyl Transferase
FCL45_RS22370	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FCL45_RS22375	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FCL45_RS22435	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
FCL45_RS22440	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
FCL45_RS22445	ENOG4105D8X	mechanosensitive ion channel
FCL45_RS22470	ENOG4105QAX	Iron-sulfur
FCL45_RS22500	ENOG4105BZU	Histidine kinase
FCL45_RS22510	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
FCL45_RS22515	ENOG4105CPF	Cell wall formation (By similarity)
FCL45_RS22520	ENOG4105CQB	FAD linked oxidase domain protein
FCL45_RS22530	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FCL45_RS22540	ENOG4108Z4T	Peptidase M50
FCL45_RS22545	ENOG4108IQE	Amp-dependent synthetase and ligase
FCL45_RS22550	ENOG4105DZ1	carboxypeptidase
FCL45_RS22555	ENOG4105C0B	DNA polymerase III (alpha subunit)
FCL45_RS22560	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
FCL45_RS22570	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
FCL45_RS22585	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
FCL45_RS22590	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
FCL45_RS22600	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS22605	ENOG4105BZN	citrate synthase
FCL45_RS22645	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
FCL45_RS22665	ENOG4105CI3	gtp-binding protein typa
FCL45_RS22670	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
FCL45_RS22680	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
FCL45_RS22710	ENOG4107U53	septum site-determining protein minD
FCL45_RS22735	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL45_RS22745	ENOG4105CV6	ABC transporter, permease
FCL45_RS22750	ENOG4108I0Y	(ABC) transporter
FCL45_RS22755	ENOG4105BZ1	(ABC) transporter
FCL45_RS22760	ENOG4105BZ1	(ABC) transporter
FCL45_RS22780	ENOG4105BZU	Histidine kinase
FCL45_RS22785	ENOG4105KAK	Plasmid pRiA4b ORF-3 family protein
FCL45_RS22790	ENOG4107QUV	Domain protein
FCL45_RS22805	ENOG4105VCQ	rubredoxin
FCL45_RS22835	ENOG4105GIJ	Glycine betaine
FCL45_RS22840	ENOG4108HQS	Glycine betaine
FCL45_RS22845	ENOG4108IJ7	Glycine betaine
FCL45_RS22865	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
FCL45_RS22870	ENOG41069P5	Protein slyX homolog
FCL45_RS22880	ENOG4107AYK	membrAne
FCL45_RS22885	ENOG410829K	Lysine exporter protein (Lyse ygga)
FCL45_RS22895	ENOG4107QN2	dihydrolipoyl dehydrogenase
FCL45_RS22900	ENOG4107QSN	dihydrolipoamide acetyltransferase
FCL45_RS22905	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
FCL45_RS22920	ENOG4107QWW	Cell wall formation (By similarity)
FCL45_RS22930	ENOG4105E51	psp operon transcriptional activator
FCL45_RS22935	ENOG41087YS	Phage shock protein A
FCL45_RS22950	ENOG410667J	hydrolase
FCL45_RS22960	ENOG4108YZY	peptidylprolyl cis-trans isomerase
FCL45_RS22970	ENOG4105CGZ	zinc metallopeptidase
FCL45_RS22975	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FCL45_RS23010	ENOG4105C2D	reductase
FCL45_RS23015	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FCL45_RS23020	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FCL45_RS23030	ENOG4107IQ5	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FCL45_RS23085	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
FCL45_RS23110	ENOG41082EJ	Flavodoxin
FCL45_RS23125	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
FCL45_RS23130	ENOG4105BZS	acriflavin resistance protein
FCL45_RS23135	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
FCL45_RS23145	ENOG4105ETX	regulatoR
FCL45_RS23150	ENOG4105GR3	Histidine kinase
FCL45_RS23155	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
FCL45_RS23160	ENOG4105CI1	PTS System
FCL45_RS23215	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
FCL45_RS23220	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
FCL45_RS23230	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
FCL45_RS23250	ENOG4107XI7	Tetr family transcriptional regulator
FCL45_RS23255	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
FCL45_RS23280	ENOG4105VEQ	Cold shock protein
FCL45_RS23290	ENOG4105C8N	cysteinyl-tRNA synthetase
FCL45_RS23305	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
FCL45_RS23310	ENOG4108YZA	Nitrogen regulatory protein pii
FCL45_RS23315	ENOG4105BZU	Histidine kinase
FCL45_RS23335	ENOG4107QKV	phosphomannomutase
FCL45_RS23340	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
FCL45_RS23370	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
FCL45_RS23445	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
FCL45_RS23450	ENOG4105J5G	Transferase hexapeptide repeat containing protein
FCL45_RS23455	ENOG4108IAJ	Nad-dependent epimerase dehydratase
FCL45_RS23460	ENOG4105CVN	desaturase
FCL45_RS23465	ENOG4105K64	Glycosyl transferase, family 2
FCL45_RS23475	ENOG4107R8N	Glycosyl transferase, family 2
FCL45_RS23480	ENOG4107UU3	sucrose-phosphate synthase (EC 2.4.1.14)
FCL45_RS23490	ENOG4105CKK	Glycosyl transferase, family 2
FCL45_RS23505	ENOG4108KMV	Glycosyl transferase (Group 1
FCL45_RS23510	ENOG4105K64	Glycosyl transferase, family 2
FCL45_RS23530	ENOG4108SHN	Glycosyl transferase, family 2
FCL45_RS23545	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
FCL45_RS23585	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
FCL45_RS23590	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
FCL45_RS23600	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FCL45_RS23610	ENOG41084AH	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
FCL45_RS23620	ENOG4108BSC	Methyltransferase
FCL45_RS23625	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
FCL45_RS23630	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
FCL45_RS23640	ENOG4105WH1	Two component transcriptional regulator luxr family
FCL45_RS23650	ENOG4105CHH	sulfate transporter
FCL45_RS23655	ENOG4105DN9	Na H antiporter
FCL45_RS23660	ENOG4105CCT	upf0313 protein
FCL45_RS23665	ENOG4108QV3	biosynthesis protein
FCL45_RS23675	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
FCL45_RS23680	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
FCL45_RS23690	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
FCL45_RS23695	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
FCL45_RS23700	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
FCL45_RS23705	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
FCL45_RS23710	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
FCL45_RS23715	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
FCL45_RS23720	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FCL45_RS23725	ENOG410835G	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
FCL45_RS23735	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
FCL45_RS23760	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
FCL45_RS23770	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
FCL45_RS23775	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
FCL45_RS23780	ENOG4107ZC0	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
FCL45_RS23785	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
FCL45_RS23795	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
FCL45_RS23800	ENOG4105FE9	pseudouridine synthase
FCL45_RS23805	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
FCL45_RS23810	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
FCL45_RS23820	ENOG4105VH4	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FCL45_RS23825	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
FCL45_RS23840	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
FCL45_RS23845	ENOG4105K63	Thioredoxin
FCL45_RS23850	ENOG4105C3M	thioredoxin reductase
FCL45_RS23855	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FCL45_RS23875	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FCL45_RS23900	ENOG4105C2X	Arabinose 5-phosphate isomerase
FCL45_RS23905	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
FCL45_RS23910	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
FCL45_RS23920	ENOG4105Z0W	Dissimilatory sulfite reductase D
FCL45_RS23925	ENOG4105PJW	Sulfite reductase dissimilatory-type beta subunit
FCL45_RS23930	ENOG4105CY1	sulfite reductase, dissimilatory-type alpha subunit
FCL45_RS23935	ENOG4107QP8	phosphohexose isomerase
FCL45_RS23940	ENOG4105DJV	ribulose-phosphate 3-epimerase
FCL45_RS23950	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FCL45_RS23955	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
FCL45_RS23970	ENOG4107QZF	nitrite reductase NADPH large subunit
FCL45_RS23975	ENOG4105CP7	Triose-phosphate isomerase
FCL45_RS23980	ENOG4105VZ9	UPF0235 protein
FCL45_RS23995	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
FCL45_RS24000	ENOG4105MA4	psp1 domain protein
FCL45_RS24005	ENOG4107QRG	dna polymerase iii
FCL45_RS24010	ENOG4105EQI	Metal Dependent Phosphohydrolase
FCL45_RS24015	ENOG4105C3G	gtp-binding protein
FCL45_RS24020	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
FCL45_RS24025	ENOG4105CHR	reductase
FCL45_RS24035	ENOG4105C7B	Threonine dehydratase
FCL45_RS24040	ENOG4108DBC	nitroreductase
FCL45_RS24075	ENOG41080WF	Electron transport complex, RnfABCDGE type, G subunit
FCL45_RS24105	ENOG4107EFR	Flavocytochrome c
FCL45_RS24115	ENOG41061ZR	Transcriptional regulator
FCL45_RS24145	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
FCL45_RS24155	ENOG4105VUC	UPF0237 protein
FCL45_RS24160	ENOG4105CAG	UPF0210 protein
FCL45_RS24165	ENOG4107YZX	Universal stress protein
FCL45_RS24185	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
FCL45_RS24200	ENOG4108PYU	two-component system response regulator
FCL45_RS24210	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
FCL45_RS24220	ENOG4108IY8	ABC, transporter
FCL45_RS24230	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
FCL45_RS24245	ENOG4105D1Q	UPF0246 protein
FCL45_RS24280	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
FCL45_RS24290	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
FCL45_RS24300	ENOG4105C1Q	protoporphyrinogen oxidase