locus-tag	class	description
FCL46_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
FCL46_RS00010	ENOG4105C1Q	protoporphyrinogen oxidase
FCL46_RS00020	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
FCL46_RS00030	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
FCL46_RS00040	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FCL46_RS00060	ENOG4108USZ	hydrogenase
FCL46_RS00065	ENOG4105D1Q	UPF0246 protein
FCL46_RS00080	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
FCL46_RS00090	ENOG4108IY8	ABC, transporter
FCL46_RS00100	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
FCL46_RS00110	ENOG4108PYU	two-component system response regulator
FCL46_RS00130	ENOG4105CAG	UPF0210 protein
FCL46_RS00135	ENOG4105VUC	UPF0237 protein
FCL46_RS00145	ENOG4105BZU	Histidine kinase
FCL46_RS00150	ENOG4105C7B	Threonine dehydratase
FCL46_RS00160	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
FCL46_RS00165	ENOG4105C3G	gtp-binding protein
FCL46_RS00170	ENOG4105EQI	Metal Dependent Phosphohydrolase
FCL46_RS00175	ENOG4105FA2	dna polymerase iii
FCL46_RS00180	ENOG4105MA4	psp1 domain protein
FCL46_RS00185	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
FCL46_RS00200	ENOG4105VZ9	UPF0235 protein
FCL46_RS00205	ENOG4105CP7	Triose-phosphate isomerase
FCL46_RS00215	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
FCL46_RS00220	ENOG4108HU6	Metal dependent phosphohydrolase
FCL46_RS00225	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FCL46_RS00235	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
FCL46_RS00250	ENOG4105DJV	ribulose-phosphate 3-epimerase
FCL46_RS00255	ENOG4107QP8	phosphohexose isomerase
FCL46_RS00260	ENOG4105CY1	sulfite reductase, dissimilatory-type alpha subunit
FCL46_RS00265	ENOG4105PJW	Sulfite reductase dissimilatory-type beta subunit
FCL46_RS00270	ENOG4105Z0W	Dissimilatory sulfite reductase D
FCL46_RS00275	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
FCL46_RS00280	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
FCL46_RS00285	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
FCL46_RS00290	ENOG4105C2X	Arabinose 5-phosphate isomerase
FCL46_RS00315	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FCL46_RS00320	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
FCL46_RS00340	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FCL46_RS00345	ENOG4105C3M	thioredoxin reductase
FCL46_RS00350	ENOG4105K63	Thioredoxin
FCL46_RS00355	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
FCL46_RS00370	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
FCL46_RS00375	ENOG4105VH4	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FCL46_RS00380	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
FCL46_RS00385	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
FCL46_RS00390	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
FCL46_RS00395	ENOG4105FE9	pseudouridine synthase
FCL46_RS00400	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
FCL46_RS00410	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
FCL46_RS00430	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
FCL46_RS00450	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FCL46_RS00460	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
FCL46_RS00470	ENOG410835G	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
FCL46_RS00475	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FCL46_RS00480	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
FCL46_RS00485	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
FCL46_RS00490	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
FCL46_RS00495	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
FCL46_RS00500	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
FCL46_RS00505	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
FCL46_RS00515	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
FCL46_RS00530	ENOG4108QV3	biosynthesis protein
FCL46_RS00535	ENOG4105CCT	upf0313 protein
FCL46_RS00545	ENOG4105CHH	sulfate transporter
FCL46_RS00555	ENOG4105WH1	Two component transcriptional regulator luxr family
FCL46_RS00565	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
FCL46_RS00570	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
FCL46_RS00575	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
FCL46_RS00580	ENOG4105VG0	50S ribosomal protein l34
FCL46_RS00585	ENOG41084AH	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
FCL46_RS00595	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FCL46_RS00605	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
FCL46_RS00610	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
FCL46_RS00645	ENOG4105CKK	Glycosyl transferase, family 2
FCL46_RS00660	ENOG4107QPH	glycogen) synthase
FCL46_RS00665	ENOG4107RA4	Glycosyl transferase (Group 1
FCL46_RS00730	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
FCL46_RS00760	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
FCL46_RS00765	ENOG4107QKV	phosphomannomutase
FCL46_RS00770	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
FCL46_RS00785	ENOG4105BZU	Histidine kinase
FCL46_RS00790	ENOG4108YZA	Nitrogen regulatory protein pii
FCL46_RS00795	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
FCL46_RS00810	ENOG4105C8N	cysteinyl-tRNA synthetase
FCL46_RS00830	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FCL46_RS00870	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
FCL46_RS00930	ENOG4105CPK	Glycosyl transferase (Group 1
FCL46_RS00950	ENOG4107XB0	Lipopolysaccharide 1,2-N-acetylglucosaminetransferase
FCL46_RS00960	ENOG4107RA4	Glycosyl transferase (Group 1
FCL46_RS00965	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FCL46_RS00980	ENOG4105D75	Capsular exopolysaccharide family
FCL46_RS01020	ENOG4105BZ4	penicillin-binding protein
FCL46_RS01025	ENOG4107RIQ	Sulfate adenylate transferase
FCL46_RS01050	ENOG410667J	hydrolase
FCL46_RS01065	ENOG41087YS	Phage shock protein A
FCL46_RS01070	ENOG4105E51	psp operon transcriptional activator
FCL46_RS01090	ENOG4105D4A	Cell wall formation (By similarity)
FCL46_RS01105	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
FCL46_RS01110	ENOG4107QSN	dihydrolipoamide acetyltransferase
FCL46_RS01115	ENOG4107QN2	dihydrolipoyl dehydrogenase
FCL46_RS01120	ENOG4105C4R	Atp-dependent dna helicase
FCL46_RS01130	ENOG4107AYK	membrAne
FCL46_RS01170	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
FCL46_RS01205	ENOG4105ECK	Fatty Acid Desaturase
FCL46_RS01220	ENOG4105VCQ	rubredoxin
FCL46_RS01225	ENOG4105DC7	peptidase M24
FCL46_RS01230	ENOG4107QUV	Domain protein
FCL46_RS01235	ENOG4105KAK	Plasmid pRiA4b ORF-3 family protein
FCL46_RS01245	ENOG4105BZU	Histidine kinase
FCL46_RS01275	ENOG4105BZ1	(ABC) transporter
FCL46_RS01280	ENOG4105BZ1	(ABC) transporter
FCL46_RS01285	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FCL46_RS01295	ENOG4108UJV	acyl-CoA thioesterase i
FCL46_RS01300	ENOG4108JUB	Transcriptional regulator
FCL46_RS01340	ENOG4105DY8	decarboxylase
FCL46_RS01345	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
FCL46_RS01360	ENOG4105CI3	gtp-binding protein typa
FCL46_RS01375	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
FCL46_RS01410	ENOG4105DGN	Electron transport complex
FCL46_RS01415	ENOG4105DZB	Electron transport complex
FCL46_RS01425	ENOG4105D6A	Electron transport complex
FCL46_RS01460	ENOG4105CGH	5'-nucleotidase
FCL46_RS01485	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
FCL46_RS01495	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
FCL46_RS01500	ENOG4105C0B	DNA polymerase III (alpha subunit)
FCL46_RS01505	ENOG4105DZ1	carboxypeptidase
FCL46_RS01510	ENOG4108IQE	Amp-dependent synthetase and ligase
FCL46_RS01520	ENOG4108Z4T	Peptidase M50
FCL46_RS01530	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FCL46_RS01540	ENOG4105CQB	FAD linked oxidase domain protein
FCL46_RS01545	ENOG4105CPF	Cell wall formation (By similarity)
FCL46_RS01550	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
FCL46_RS01560	ENOG4105BZU	Histidine kinase
FCL46_RS01570	ENOG4108M11	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FCL46_RS01590	ENOG4105QAX	Iron-sulfur
FCL46_RS01600	ENOG4105D3R	alkyl hydroperoxide reductase
FCL46_RS01615	ENOG4105D8X	mechanosensitive ion channel
FCL46_RS01625	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
FCL46_RS01630	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
FCL46_RS01655	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
FCL46_RS01680	ENOG4105BZ1	(ABC) transporter
FCL46_RS01700	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FCL46_RS01705	ENOG4107RBB	ABC transporter, permease
FCL46_RS01725	ENOG4105CG5	Glycosyl transferase (Group 1
FCL46_RS01755	ENOG4105BZU	Histidine kinase
FCL46_RS01760	ENOG4105DVT	helicase
FCL46_RS01765	ENOG4105EAH	synthase
FCL46_RS01770	ENOG4105CK5	oxidoreductase
FCL46_RS01785	ENOG4105DC1	bifunctional purine biosynthesis protein purh
FCL46_RS01790	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
FCL46_RS01795	ENOG4105BZ1	(ABC) transporter
FCL46_RS01835	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FCL46_RS01850	ENOG4105CTQ	phosphohexokinase
FCL46_RS01860	ENOG4105BZE	flagellar hook protein, FlgE
FCL46_RS01870	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
FCL46_RS01880	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
FCL46_RS01885	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
FCL46_RS01895	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
FCL46_RS01920	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
FCL46_RS01935	ENOG4105CNI	cell division protein FtsW
FCL46_RS01940	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
FCL46_RS01950	ENOG4105C2M	dna polymerase I
FCL46_RS01960	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
FCL46_RS01970	ENOG4105EPW	hflc protein
FCL46_RS01975	ENOG4107RIZ	hflk protein
FCL46_RS02015	ENOG4108R6K	riboflavin synthase, subunit alpha
FCL46_RS02020	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
FCL46_RS02025	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
FCL46_RS02030	ENOG4105M7K	Involved in the transcription termination process (By similarity)
FCL46_RS02035	ENOG4105CNU	cell division protein FtsK
FCL46_RS02050	ENOG4105EWK	phytoene
FCL46_RS02085	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
FCL46_RS02090	ENOG41084ED	50S ribosomal protein L33
FCL46_RS02105	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
FCL46_RS02110	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
FCL46_RS02115	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
FCL46_RS02120	ENOG4108VZM	50s ribosomal protein L10
FCL46_RS02125	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
FCL46_RS02130	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FCL46_RS02135	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FCL46_RS02140	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
FCL46_RS02145	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
FCL46_RS02150	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FCL46_RS02155	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
FCL46_RS02160	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
FCL46_RS02165	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
FCL46_RS02170	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
FCL46_RS02175	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
FCL46_RS02180	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FCL46_RS02185	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
FCL46_RS02190	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
FCL46_RS02195	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
FCL46_RS02200	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
FCL46_RS02205	ENOG41082SA	50s ribosomal protein l29
FCL46_RS02210	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
FCL46_RS02215	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
FCL46_RS02220	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
FCL46_RS02225	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FCL46_RS02230	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
FCL46_RS02245	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
FCL46_RS02250	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
FCL46_RS02255	ENOG4105VPB	50S ribosomal protein L30
FCL46_RS02260	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
FCL46_RS02265	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
FCL46_RS02275	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
FCL46_RS02280	ENOG41086F9	50S ribosomal protein L36
FCL46_RS02285	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FCL46_RS02290	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
FCL46_RS02295	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
FCL46_RS02300	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FCL46_RS02305	ENOG4108ZT0	50S ribosomal protein l17
FCL46_RS02315	ENOG4105CE9	30S ribosomal protein S2
FCL46_RS02320	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
FCL46_RS02325	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
FCL46_RS02330	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
FCL46_RS02335	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
FCL46_RS02340	ENOG4105KNE	Phosphatidate cytidylyltransferase
FCL46_RS02345	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
FCL46_RS02350	ENOG4105DZP	Membrane-associated zinc metalloprotease
FCL46_RS02355	ENOG41072GX	Peptidase M22 Glycoprotease
FCL46_RS02360	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
FCL46_RS02365	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
FCL46_RS02370	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
FCL46_RS02390	ENOG4105C8Q	Methyl-accepting chemotaxis
FCL46_RS02395	ENOG4108V1T	peptidylprolyl cis-trans isomerase
FCL46_RS02410	ENOG4105WMR	Protein CrcB homolog
FCL46_RS02420	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
FCL46_RS02485	ENOG4105VEQ	Cold shock protein
FCL46_RS02500	ENOG4105CF7	AraC family transcriptional regulator
FCL46_RS02505	ENOG4108I6A	alcohol dehydrogenase
FCL46_RS02515	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
FCL46_RS02520	ENOG4105BZU	Histidine kinase
FCL46_RS02525	ENOG4105D0M	Protease HtpX homolog
FCL46_RS02570	ENOG4105D9M	gamma-glutamylcysteine synthetase
FCL46_RS02590	ENOG4105BZU	Histidine kinase
FCL46_RS02595	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
FCL46_RS02610	ENOG4108N5C	SNARE associated Golgi protein-related protein
FCL46_RS02670	ENOG4105CVJ	phosphoglycerate mutase
FCL46_RS02685	ENOG41082EJ	Flavodoxin
FCL46_RS02695	ENOG4108V0P	LemA family
FCL46_RS02720	ENOG4105G5W	regulator Fur family
FCL46_RS02725	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
FCL46_RS02735	ENOG4105KVH	Transcriptional regulator
FCL46_RS02805	ENOG4105CVE	Lytic murein transglycosylase
FCL46_RS02810	ENOG4108ZG0	Ompa motb domain protein
FCL46_RS02820	ENOG4105CZK	Aspartate kinase
FCL46_RS02830	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FCL46_RS02835	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FCL46_RS02840	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FCL46_RS02860	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
FCL46_RS02880	ENOG4105D65	subunit l
FCL46_RS02890	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FCL46_RS02895	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FCL46_RS02905	ENOG410828M	hemerythrin-like, metal-binding protein
FCL46_RS02915	ENOG4105BZ4	penicillin-binding protein
FCL46_RS02920	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
FCL46_RS02925	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
FCL46_RS02935	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
FCL46_RS02990	ENOG4105K8R	UPF0145 protein
FCL46_RS03005	ENOG4105DAA	L-lactate
FCL46_RS03010	ENOG4105CQB	FAD linked oxidase domain protein
FCL46_RS03015	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
FCL46_RS03040	ENOG4105BZU	Histidine kinase
FCL46_RS03045	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
FCL46_RS03055	ENOG4105BZU	Histidine kinase
FCL46_RS03075	ENOG4105N1F	Hnh endonuclease
FCL46_RS03080	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
FCL46_RS03095	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS03105	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS03115	ENOG4105JAB	phenazine biosynthesis protein, phzf family
FCL46_RS03140	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FCL46_RS03145	ENOG4105BZU	Histidine kinase
FCL46_RS03155	ENOG4105CKW	Inner membrane protein yedI
FCL46_RS03170	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FCL46_RS03185	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS03200	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS03205	ENOG4105ETX	regulatoR
FCL46_RS03210	ENOG410812K	response regulator receiver protein
FCL46_RS03215	ENOG4108ZXC	Two component transcriptional regulator, luxr family
FCL46_RS03230	ENOG4105D0M	Protease HtpX homolog
FCL46_RS03235	ENOG4105C8Q	Methyl-accepting chemotaxis
FCL46_RS03255	ENOG4105BZU	Histidine kinase
FCL46_RS03260	ENOG41080IJ	Diacylglycerol kinase
FCL46_RS03290	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
FCL46_RS03300	ENOG4105CJW	magnesium transporter
FCL46_RS03305	ENOG4107VAM	peptidase, m28
FCL46_RS03315	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
FCL46_RS03335	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
FCL46_RS03455	ENOG4105DNP	FAD linked oxidase domain protein
FCL46_RS03460	ENOG4107SGM	protein serine threonine phosphatase
FCL46_RS03475	ENOG4105C8Q	Methyl-accepting chemotaxis
FCL46_RS03480	ENOG4108JUA	Transcriptional regulator
FCL46_RS03515	ENOG4105DZQ	phospholipase D Transphosphatidylase
FCL46_RS03540	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
FCL46_RS03555	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
FCL46_RS03565	ENOG4105ENH	Sulfatase
FCL46_RS03595	ENOG4105BZU	Histidine kinase
FCL46_RS03610	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL46_RS03620	ENOG4105GQU	Trap dicarboxylate transporter, dctp subunit
FCL46_RS03625	ENOG4105ETE	Transcriptional regulator (LacI family
FCL46_RS03655	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
FCL46_RS03670	ENOG4105C8U	phosphate abc transporter
FCL46_RS03675	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
FCL46_RS03680	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FCL46_RS03685	ENOG4105BZU	Histidine kinase
FCL46_RS03690	ENOG4105BZU	Histidine kinase
FCL46_RS03700	ENOG4105BZU	Histidine kinase
FCL46_RS03715	ENOG4108Z4K	mutator MutT protein
FCL46_RS03735	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
FCL46_RS03740	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
FCL46_RS03745	ENOG4105G5W	regulator Fur family
FCL46_RS03750	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FCL46_RS03765	ENOG4105KCK	Peptidoglycan-associated lipoprotein
FCL46_RS03775	ENOG4105DSJ	YicC domain protein
FCL46_RS03780	ENOG4105KC4	UPF0296 protein
FCL46_RS03785	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
FCL46_RS03790	ENOG4105C2N	RNA methyltransferase TrmH family group 3
FCL46_RS03795	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
FCL46_RS03815	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
FCL46_RS03825	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
FCL46_RS03835	ENOG4105E63	Pfam:DUF178
FCL46_RS03845	ENOG4105EB3	Histidine kinase
FCL46_RS03880	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FCL46_RS03895	ENOG4107R37	Glutamate dehydrogenase
FCL46_RS03900	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
FCL46_RS03935	ENOG4105BZU	Histidine kinase
FCL46_RS03940	ENOG4105D1H	recombination factor protein RarA
FCL46_RS04010	ENOG4105CDU	Replicative dna helicase
FCL46_RS04050	ENOG4105CH5	extracellular solute-binding protein, family 7
FCL46_RS04060	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
FCL46_RS04070	ENOG4105KST	dependent repressor
FCL46_RS04075	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
FCL46_RS04090	ENOG4105E2K	Glycosyl transferase (Group 1
FCL46_RS04100	ENOG4105CUY	Mechanosensitive ion channel
FCL46_RS04110	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
FCL46_RS04115	ENOG4105CDY	transcriptional regulatory protein
FCL46_RS04125	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
FCL46_RS04130	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
FCL46_RS04135	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
FCL46_RS04140	ENOG4108V6E	Cell division protein mraZ
FCL46_RS04145	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
FCL46_RS04155	ENOG4105CJN	penicillin-binding protein
FCL46_RS04160	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
FCL46_RS04165	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
FCL46_RS04170	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
FCL46_RS04175	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
FCL46_RS04180	ENOG4105DFU	Cell wall formation (By similarity)
FCL46_RS04185	ENOG410812A	polypeptide-transport-associated domain protein, FtsQ-type
FCL46_RS04190	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
FCL46_RS04195	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
FCL46_RS04200	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FCL46_RS04205	ENOG4105BZU	Histidine kinase
FCL46_RS04210	ENOG4108T5I	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
FCL46_RS04220	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
FCL46_RS04225	ENOG4108VYJ	response regulator receiver protein
FCL46_RS04275	ENOG4105D17	glycoside hydrolase, family 3 domain protein
FCL46_RS04280	ENOG4105BZU	Histidine kinase
FCL46_RS04290	ENOG4105C4R	Atp-dependent dna helicase
FCL46_RS04295	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
FCL46_RS04335	ENOG4105C8Q	Methyl-accepting chemotaxis
FCL46_RS04375	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FCL46_RS04380	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FCL46_RS04385	ENOG4108MP6	LysR family Transcriptional regulator
FCL46_RS04395	ENOG4105DHZ	alpha beta
FCL46_RS04400	ENOG4105DZ0	fad dependent oxidoreductase
FCL46_RS04415	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
FCL46_RS04450	ENOG4105CFU	surface antigen
FCL46_RS04465	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FCL46_RS04470	ENOG4105CD5	CoA-binding domain protein
FCL46_RS04490	ENOG4105D64	Mechanosensitive ion channel
FCL46_RS04495	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL46_RS04505	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
FCL46_RS04510	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS04515	ENOG4105CQZ	Histidine kinase
FCL46_RS04520	ENOG4108JUB	Transcriptional regulator
FCL46_RS04525	ENOG4108JPW	Aminotransferase
FCL46_RS04530	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
FCL46_RS04555	ENOG4105W87	Cbs domain
FCL46_RS04585	ENOG4108JUA	Transcriptional regulator
FCL46_RS04590	ENOG4105CBG	Sulfatase
FCL46_RS04605	ENOG4105C94	Transporter
FCL46_RS04625	ENOG4108Z5K	methylglyoxal synthase
FCL46_RS04645	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
FCL46_RS04660	ENOG4107T8V	it plays a direct role in the translocation of protons across the membrane (By similarity)
FCL46_RS04670	ENOG4108Q71	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
FCL46_RS04675	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
FCL46_RS04680	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
FCL46_RS04690	ENOG4105D0S	secretion protein (HlyD
FCL46_RS04690	ENOG4105D0S	secretion protein (HlyD
FCL46_RS04695	ENOG4105CJ1	ABC, transporter
FCL46_RS04700	ENOG4107QWP	ABC-2 type transporter
FCL46_RS04705	ENOG4107QWP	ABC-2 type transporter
FCL46_RS04725	ENOG4105CPN	adenine deaminase
FCL46_RS04730	ENOG4108VAU	general secretion pathway protein G
FCL46_RS04735	ENOG4108ESY	Metal dependent phosphohydrolase
FCL46_RS04755	ENOG4108ESY	Metal dependent phosphohydrolase
FCL46_RS04790	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
FCL46_RS04805	ENOG4105D52	delta-aminolevulinic acid dehydratase
FCL46_RS04810	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS04815	ENOG4105ES5	Histidine kinase
FCL46_RS04830	ENOG4105VYW	UPF0251 protein
FCL46_RS04835	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
FCL46_RS04845	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
FCL46_RS04850	ENOG4105EYH	Exonuclease
FCL46_RS04855	ENOG4107RH8	nuclease SbcCD subunit D
FCL46_RS04860	ENOG410829K	Lysine exporter protein (Lyse ygga)
FCL46_RS04890	ENOG4108KMV	Glycosyl transferase (Group 1
FCL46_RS04900	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
FCL46_RS04925	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
FCL46_RS04930	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
FCL46_RS04935	ENOG41082RQ	UPF0102 protein
FCL46_RS04940	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FCL46_RS04945	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
FCL46_RS04950	ENOG4108WTY	tRNA (Guanine-N(1)-)-methyltransferase
FCL46_RS04955	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
FCL46_RS04960	ENOG41082N4	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
FCL46_RS04965	ENOG4105VB6	UPF0109 protein
FCL46_RS04970	ENOG4105K5M	30s ribosomal protein S16
FCL46_RS04980	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
FCL46_RS04985	ENOG4105FAE	von Willebrand factor, type A
FCL46_RS04995	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
FCL46_RS05000	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
FCL46_RS05005	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
FCL46_RS05010	ENOG4105CY3	ABC transporter, permease
FCL46_RS05045	ENOG41084CW	50S ribosomal protein L32
FCL46_RS05050	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
FCL46_RS05055	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
FCL46_RS05065	ENOG4105BZJ	Electron transfer flavoprotein
FCL46_RS05070	ENOG4105C10	Electron transfer flavoprotein
FCL46_RS05075	ENOG4105CHR	reductase
FCL46_RS05080	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FCL46_RS05085	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FCL46_RS05090	ENOG4108YZG	isomerase
FCL46_RS05095	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
FCL46_RS05100	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
FCL46_RS05105	ENOG4105FA0	parb-like partition protein
FCL46_RS05110	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
FCL46_RS05125	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
FCL46_RS05130	ENOG4105DFA	alanine racemase domain protein
FCL46_RS05135	ENOG4105F8V	Hydrolase, tatD family
FCL46_RS05145	ENOG4105CXV	gliding motility protein
FCL46_RS05165	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
FCL46_RS05170	ENOG4106H78	methyltransferase
FCL46_RS05175	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
FCL46_RS05180	ENOG4108ZP8	Acetolactate synthase small subunit
FCL46_RS05185	ENOG4105C7K	acetolactate synthase
FCL46_RS05190	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
FCL46_RS05205	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
FCL46_RS05215	ENOG4105C30	Nad-dependent epimerase dehydratase
FCL46_RS05270	ENOG4108IAJ	Nad-dependent epimerase dehydratase
FCL46_RS05275	ENOG4105CY0	Metallo-Beta-Lactamase
FCL46_RS05280	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
FCL46_RS05285	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
FCL46_RS05290	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
FCL46_RS05295	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
FCL46_RS05310	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
FCL46_RS05315	ENOG4105PSV	Polysaccharide Biosynthesis Protein
FCL46_RS05325	ENOG4107TAE	Glycosyl transferase (Group 1
FCL46_RS05335	ENOG4108UW5	maltose o-acetyltransferase
FCL46_RS05345	ENOG4105CTC	Lipopolysaccharide biosynthesis protein-like protein
FCL46_RS05355	ENOG4107S6X	Glycosyl transferase, family 2
FCL46_RS05360	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
FCL46_RS05410	ENOG4105ESV	Glycosyl transferase, family 4
FCL46_RS05430	ENOG4105D75	Capsular exopolysaccharide family
FCL46_RS05465	ENOG4108RH0	Crea protein
FCL46_RS05485	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
FCL46_RS05490	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
FCL46_RS05495	ENOG4105KY8	Rubrerythrin
FCL46_RS05500	ENOG4107TPS	domain protein
FCL46_RS05510	ENOG4105WZW	rhodanese family
FCL46_RS05520	ENOG4105CNW	domain protein
FCL46_RS05540	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FCL46_RS05545	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
FCL46_RS05555	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
FCL46_RS05575	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
FCL46_RS05580	ENOG4105C75	arginyL-tRNA synthetase
FCL46_RS05590	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
FCL46_RS05595	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
FCL46_RS05600	ENOG4105CSR	polyphosphate kinase 2
FCL46_RS05605	ENOG4105CSR	polyphosphate kinase 2
FCL46_RS05615	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
FCL46_RS05625	ENOG4107QJE	Chromosome Partitioning Protein
FCL46_RS05650	ENOG4105JKW	Valine--pyruvate aminotransferase
FCL46_RS05670	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
FCL46_RS05680	ENOG4105EMN	RNA polymerase sigma factor
FCL46_RS05690	ENOG4105CE1	Ferrous iron transport protein b
FCL46_RS05715	ENOG4105CX6	glutaminyL-tRNA synthetase
FCL46_RS05720	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
FCL46_RS05735	ENOG4107Z7S	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
FCL46_RS05745	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FCL46_RS05750	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
FCL46_RS05755	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
FCL46_RS05760	ENOG4108VJ1	Transcriptional regulator (CarD family
FCL46_RS05765	ENOG4105C34	Pseudouridine synthase
FCL46_RS05770	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
FCL46_RS05780	ENOG41082DI	50s ribosomal protein l31
FCL46_RS05785	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
FCL46_RS05790	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
FCL46_RS05795	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
FCL46_RS05810	ENOG4105BZU	Histidine kinase
FCL46_RS05815	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS05820	ENOG41082IR	Excinuclease ABC C subunit domain protein
FCL46_RS05830	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
FCL46_RS05855	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
FCL46_RS05865	ENOG41084YM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FCL46_RS05870	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FCL46_RS05875	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
FCL46_RS05880	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
FCL46_RS05895	ENOG4105C0B	DNA polymerase III (alpha subunit)
FCL46_RS05900	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
FCL46_RS05905	ENOG4105C8J	)-transporter
FCL46_RS05915	ENOG4105CBX	hi0933 family
FCL46_RS05935	ENOG4105HEE	Binding Domain protein
FCL46_RS05945	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
FCL46_RS05950	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FCL46_RS05955	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
FCL46_RS05960	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
FCL46_RS05965	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
FCL46_RS05970	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FCL46_RS05975	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS06005	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
FCL46_RS06015	ENOG4105CRK	lysyL-tRNA synthetase
FCL46_RS06020	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
FCL46_RS06030	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FCL46_RS06035	ENOG4105CFG	Acts as a chaperone (By similarity)
FCL46_RS06050	ENOG4105CTD	carboxy-peptidase
FCL46_RS06065	ENOG4105D94	Major Facilitator Superfamily
FCL46_RS06085	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
FCL46_RS06095	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
FCL46_RS06105	ENOG4105D4P	Coproporphyrinogen iii oxidase
FCL46_RS06110	ENOG4108JQ1	Dehydrogenase
FCL46_RS06120	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
FCL46_RS06125	ENOG4108Z03	MAF-like protein
FCL46_RS06145	ENOG4107QHF	type ii secretion system protein e
FCL46_RS06165	ENOG4105BZU	Histidine kinase
FCL46_RS06170	ENOG4105BZU	Histidine kinase
FCL46_RS06175	ENOG4108JIF	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
FCL46_RS06185	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
FCL46_RS06190	ENOG4108JQC	penicillin-binding protein 1A
FCL46_RS06195	ENOG4105VEQ	Cold shock protein
FCL46_RS06205	ENOG4105CJ3	phosphate transporter
FCL46_RS06210	ENOG4107IX6	phosphate transport regulator
FCL46_RS06220	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
FCL46_RS06230	ENOG4105BZ8	glutamate synthase
FCL46_RS06250	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
FCL46_RS06255	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
FCL46_RS06260	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
FCL46_RS06270	ENOG4105D98	threonine synthase
FCL46_RS06280	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FCL46_RS06285	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
FCL46_RS06290	ENOG4105CHV	Transcription elongation factor NusA
FCL46_RS06300	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
FCL46_RS06305	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
FCL46_RS06315	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
FCL46_RS06320	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
FCL46_RS06325	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
FCL46_RS06330	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
FCL46_RS06335	ENOG4105Q2H	domain protein
FCL46_RS06340	ENOG4105HBR	Rna-binding protein
FCL46_RS06350	ENOG41068JE	domain protein
FCL46_RS06355	ENOG4108JQC	penicillin-binding protein 1A
FCL46_RS06365	ENOG4107QHF	type ii secretion system protein e
FCL46_RS06390	ENOG4105C8Q	Methyl-accepting chemotaxis
FCL46_RS06395	ENOG4105BZU	Histidine kinase
FCL46_RS06405	ENOG4107Z36	nucleotidyl transferase
FCL46_RS06485	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
FCL46_RS06490	ENOG4107SFQ	iron-sulfur binding
FCL46_RS06495	ENOG4105DB1	molybdopterin oxidoreductase
FCL46_RS06500	ENOG41080C8	DUF218 domain
FCL46_RS06505	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
FCL46_RS06515	ENOG4105BZU	Histidine kinase
FCL46_RS06530	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
FCL46_RS06550	ENOG4105HDK	L-asparaginase
FCL46_RS06555	ENOG4105BZG	amino acid carrier protein
FCL46_RS06560	ENOG4107QKW	extracellular solute-binding protein family 1
FCL46_RS06565	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
FCL46_RS06570	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FCL46_RS06575	ENOG4105EYA	deoxyribonuclease
FCL46_RS06590	ENOG4108J2R	molybdopterin oxidoreductase
FCL46_RS06665	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL46_RS06675	ENOG4105CH5	extracellular solute-binding protein, family 7
FCL46_RS06695	ENOG4105QNR	S1 RNA binding domain protein
FCL46_RS06710	ENOG4105C8Q	Methyl-accepting chemotaxis
FCL46_RS06720	ENOG4105DCF	alanine dehydrogenase
FCL46_RS06725	ENOG4105BZG	amino acid carrier protein
FCL46_RS06735	ENOG4105F04	LysR family Transcriptional regulator
FCL46_RS06745	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
FCL46_RS06750	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
FCL46_RS06760	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FCL46_RS06765	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
FCL46_RS06790	ENOG4106IPI	cyclase, family
FCL46_RS06800	ENOG4105DSP	amino acid AbC transporter
FCL46_RS06805	ENOG4105E89	ABC transporter
FCL46_RS06810	ENOG4108JEH	abc transporter atp-binding protein
FCL46_RS06815	ENOG4105BZG	amino acid carrier protein
FCL46_RS06845	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
FCL46_RS06850	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FCL46_RS06855	ENOG4105C8S	subunit m
FCL46_RS06860	ENOG4108JPZ	Monovalent cation H antiporter subunit D
FCL46_RS06870	ENOG4108JPZ	Monovalent cation H antiporter subunit D
FCL46_RS06875	ENOG4107EJQ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FCL46_RS06880	ENOG4107YX3	NADH dehydrogenase subunit j
FCL46_RS06885	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FCL46_RS06890	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
FCL46_RS06895	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FCL46_RS06900	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FCL46_RS06905	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FCL46_RS06910	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FCL46_RS06915	ENOG4108M0I	Transcriptional regulator
FCL46_RS06920	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
FCL46_RS06925	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
FCL46_RS06930	ENOG4108UJD	30S ribosomal protein S9
FCL46_RS06935	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
FCL46_RS06945	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
FCL46_RS06965	ENOG4105C5S	asparaginyl-tRNA synthetase
FCL46_RS06975	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
FCL46_RS06980	ENOG4108IQE	Amp-dependent synthetase and ligase
FCL46_RS07005	ENOG41081QV	Universal stress protein
FCL46_RS07020	ENOG4105DSY	exodeoxyribonuclease V, gamma
FCL46_RS07025	ENOG4107QKA	exodeoxyribonuclease V beta
FCL46_RS07030	ENOG4107QYX	exodeoxyribonuclease v alpha
FCL46_RS07035	ENOG4105CQB	FAD linked oxidase domain protein
FCL46_RS07045	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
FCL46_RS07070	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
FCL46_RS07075	ENOG4108ZJT	translation initiation factor, Sui1
FCL46_RS07140	ENOG4105K64	Glycosyl transferase, family 2
FCL46_RS07165	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS07170	ENOG4105BZU	Histidine kinase
FCL46_RS07180	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
FCL46_RS07185	ENOG4105WN5	stage II sporulation protein
FCL46_RS07195	ENOG41084GC	stage II sporulation protein
FCL46_RS07200	ENOG4105D3Q	Sugar transferase
FCL46_RS07215	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
FCL46_RS07220	ENOG4105DWP	Membrane
FCL46_RS07230	ENOG4105DHU	Bile acid
FCL46_RS07245	ENOG4105QUH	Domain of unknown function (DUF2088)
FCL46_RS07260	ENOG4105GQU	Trap dicarboxylate transporter, dctp subunit
FCL46_RS07265	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL46_RS07275	ENOG4105M4H	endoribonuclease L-psp
FCL46_RS07305	ENOG4107RZC	phospholipase d
FCL46_RS07315	ENOG4105DY2	Paraquat-inducible protein b
FCL46_RS07325	ENOG4105CY3	ABC transporter, permease
FCL46_RS07330	ENOG4105C1G	acyl-Coa dehydrogenase
FCL46_RS07360	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FCL46_RS07365	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FCL46_RS07375	ENOG4106HK8	GPR1 FUN34 yaaH family protein
FCL46_RS07385	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS07390	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
FCL46_RS07395	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FCL46_RS07405	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
FCL46_RS07410	ENOG4107QX3	carboxylase
FCL46_RS07425	ENOG4107QSA	Oxaloacetate decarboxylase
FCL46_RS07430	ENOG4108Z0R	Transferase
FCL46_RS07440	ENOG4105CB2	alcohol dehydrogenase
FCL46_RS07450	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
FCL46_RS07505	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
FCL46_RS07510	ENOG4105ENH	Sulfatase
FCL46_RS07515	ENOG4108VKG	metal-dependent hydrolase
FCL46_RS07530	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FCL46_RS07540	ENOG4105BZU	Histidine kinase
FCL46_RS07555	ENOG4108IYU	L-aspartate oxidase
FCL46_RS07560	ENOG4105BZU	Histidine kinase
FCL46_RS07565	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FCL46_RS07570	ENOG41083Z3	extracellular ligand-binding receptor
FCL46_RS07575	ENOG4105BZU	Histidine kinase
FCL46_RS07580	ENOG4105BZU	Histidine kinase
FCL46_RS07585	ENOG4107Z5C	methylesterase
FCL46_RS07600	ENOG4107S8C	mandelate racemase muconate lactonizing
FCL46_RS07615	ENOG4105BZU	Histidine kinase
FCL46_RS07625	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS07640	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
FCL46_RS07645	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
FCL46_RS07660	ENOG4105DGU	Histone deacetylase
FCL46_RS07665	ENOG4105EM2	membrane
FCL46_RS07685	ENOG4108Q52	Methyltransferase cognate corrinoid protein
FCL46_RS07720	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
FCL46_RS07735	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
FCL46_RS07755	ENOG4105DJT	lAO AO transport system ATPase
FCL46_RS07760	ENOG4105D5P	Methylmalonyl-coA mutase
FCL46_RS07765	ENOG4108ZVT	methylmalonyl-coA epimerase
FCL46_RS07775	ENOG4105D9Q	decarboxylase (Beta subunit)
FCL46_RS07780	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
FCL46_RS07795	ENOG4105DGU	Histone deacetylase
FCL46_RS07815	ENOG4107RZC	phospholipase d
FCL46_RS07830	ENOG4107RID	5-oxoprolinase (ATP-hydrolyzing)
FCL46_RS07855	ENOG4108JQ9	ABC transporter
FCL46_RS07865	ENOG4105RH4	Glycine cleavage system transcriptional repressor
FCL46_RS07870	ENOG4105D06	uba thif-type nad fad binding protein
FCL46_RS07895	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
FCL46_RS07905	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FCL46_RS07915	ENOG4105Y3U	Transglycosylase-associated protein
FCL46_RS07935	ENOG4105ENX	hydrolase
FCL46_RS07945	ENOG4105CV8	reductase
FCL46_RS07970	ENOG4105CPC	Aldo Keto reductase
FCL46_RS07980	ENOG4105CF7	AraC family transcriptional regulator
FCL46_RS08015	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FCL46_RS08080	ENOG4105F7P	transcriptional regulator AsnC family
FCL46_RS08095	ENOG4107QX8	SPFH domain, Band 7 family protein
FCL46_RS08120	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
FCL46_RS08125	ENOG4105W8H	transhydrogenase (subunit alpha
FCL46_RS08130	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
FCL46_RS08140	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS08145	ENOG4105E39	Enoyl-CoA hydratase
FCL46_RS08170	ENOG4108IQE	Amp-dependent synthetase and ligase
FCL46_RS08215	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
FCL46_RS08235	ENOG4105KWG	Pfam:DUF1696
FCL46_RS08250	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FCL46_RS08260	ENOG4105D94	Major Facilitator Superfamily
FCL46_RS08265	ENOG4107QUY	Guanine deaminase
FCL46_RS08270	ENOG4105C8Q	Methyl-accepting chemotaxis
FCL46_RS08295	ENOG4108I5D	sulfate abc transporter
FCL46_RS08300	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FCL46_RS08305	ENOG4105FJ0	thiamine
FCL46_RS08310	ENOG4105CEY	Amp-dependent synthetase and ligase
FCL46_RS08320	ENOG4105BZU	Histidine kinase
FCL46_RS08325	ENOG4105EKE	dihydroorotase
FCL46_RS08335	ENOG4105CYC	Transferase
FCL46_RS08340	ENOG4105ENE	Histidine kinase
FCL46_RS08350	ENOG4105CEY	Amp-dependent synthetase and ligase
FCL46_RS08355	ENOG4105E39	Enoyl-CoA hydratase
FCL46_RS08360	ENOG4105CHU	acetyl-coa acetyltransferase
FCL46_RS08365	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
FCL46_RS08375	ENOG4105C1G	acyl-Coa dehydrogenase
FCL46_RS08380	ENOG4105DF6	Fe-S oxidoreductase
FCL46_RS08385	ENOG4105BZJ	Electron transfer flavoprotein
FCL46_RS08390	ENOG4105C10	Electron transfer flavoprotein
FCL46_RS08395	ENOG4108ZP8	Acetolactate synthase small subunit
FCL46_RS08405	ENOG4105EJ9	Membrane
FCL46_RS08430	ENOG4105C5Q	Transcriptional regulator
FCL46_RS08435	ENOG4105BZU	Histidine kinase
FCL46_RS08440	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FCL46_RS08475	ENOG4105BZU	Histidine kinase
FCL46_RS08505	ENOG4105EWK	phytoene
FCL46_RS08540	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
FCL46_RS08545	ENOG4107QIZ	NADH dehydrogenase
FCL46_RS08575	ENOG4105CV8	reductase
FCL46_RS08580	ENOG4105BZU	Histidine kinase
FCL46_RS08585	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
FCL46_RS08620	ENOG4105CKU	formyltetrahydrofolate synthetase
FCL46_RS08625	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
FCL46_RS08630	ENOG41085GJ	domain protein
FCL46_RS08640	ENOG41076HS	cation diffusion facilitator family transporter
FCL46_RS08655	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
FCL46_RS08685	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
FCL46_RS08690	ENOG4105D8V	Glucose sorbosone dehydrogenase
FCL46_RS08700	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
FCL46_RS08730	ENOG4107RJC	Iron-containing alcohol dehydrogenase
FCL46_RS08735	ENOG4105M3Z	response regulator
FCL46_RS08760	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
FCL46_RS08770	ENOG4105C8Q	Methyl-accepting chemotaxis
FCL46_RS08800	ENOG4105CGK	Exodeoxyribonuclease III
FCL46_RS08805	ENOG4105EAQ	(twin-arginine translocation) pathway signal
FCL46_RS08820	ENOG4105EW9	transcriptional regulator AsnC family
FCL46_RS08840	ENOG4107U32	Beta-lactamase domain protein
FCL46_RS08845	ENOG4105CKK	Glycosyl transferase, family 2
FCL46_RS08850	ENOG4105C9Q	fumarate hydratase class II
FCL46_RS08860	ENOG4105MAX	Superoxide reductase
FCL46_RS08885	ENOG4105CCU	oxidase (Subunit III)
FCL46_RS08900	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
FCL46_RS08910	ENOG41090A1	ferritin
FCL46_RS08920	ENOG4105D3R	alkyl hydroperoxide reductase
FCL46_RS08925	ENOG4105VCQ	rubredoxin
FCL46_RS08935	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
FCL46_RS08940	ENOG4107TH8	cina domain protein
FCL46_RS08945	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FCL46_RS08950	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
FCL46_RS08955	ENOG4105CFP	Peptidase U32
FCL46_RS08960	ENOG4107GFK	fumarate
FCL46_RS08980	ENOG4105C28	cystathionine
FCL46_RS09000	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FCL46_RS09005	ENOG4105DVY	radical SAM domain protein
FCL46_RS09010	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
FCL46_RS09015	ENOG4105EV6	Pfam:DUF178
FCL46_RS09020	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
FCL46_RS09025	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
FCL46_RS09035	ENOG4105C8V	SAICAR synthetase
FCL46_RS09045	ENOG4105ECP	epimerase
FCL46_RS09050	ENOG4105VXR	cytoplasmic protein
FCL46_RS09055	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
FCL46_RS09085	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
FCL46_RS09090	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS09115	ENOG4105HMI	Membrane
FCL46_RS09115	ENOG4105HMI	Membrane
FCL46_RS09120	ENOG4107RAN	Peptidase, M16
FCL46_RS09160	ENOG4105E0A	ABC, transporter
FCL46_RS09165	ENOG4105EHG	Permease protein
FCL46_RS09180	ENOG4105D07	Signal peptide peptidase, SppA
FCL46_RS09185	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
FCL46_RS09190	ENOG4105IJJ	transcriptional regulator, crp fnr family
FCL46_RS09215	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
FCL46_RS09220	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
FCL46_RS09225	ENOG4105BZS	acriflavin resistance protein
FCL46_RS09230	ENOG4105ETX	regulatoR
FCL46_RS09235	ENOG4107WP9	Histidine kinase
FCL46_RS09240	ENOG4108IG5	Transcriptional regulator
FCL46_RS09245	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
FCL46_RS09250	ENOG4105BZS	acriflavin resistance protein
FCL46_RS09255	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
FCL46_RS09270	ENOG4107R7Y	intracellular protease Pfpi family
FCL46_RS09300	ENOG4105CSR	polyphosphate kinase 2
FCL46_RS09305	ENOG4105CSR	polyphosphate kinase 2
FCL46_RS09335	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
FCL46_RS09340	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
FCL46_RS09350	ENOG4105C4R	Atp-dependent dna helicase
FCL46_RS09410	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
FCL46_RS09420	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL46_RS09445	ENOG4105CQZ	Histidine kinase
FCL46_RS09450	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
FCL46_RS09455	ENOG4105ETE	Transcriptional regulator (LacI family
FCL46_RS09460	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
FCL46_RS09470	ENOG4105CNN	ABC, transporter
FCL46_RS09475	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
FCL46_RS09480	ENOG4108RVA	ribokinase
FCL46_RS09485	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
FCL46_RS09520	ENOG4108DBC	nitroreductase
FCL46_RS09530	ENOG4105E3A	(ABC) transporter
FCL46_RS09535	ENOG4105DA5	(ABC) transporter
FCL46_RS09550	ENOG4108IJ7	Glycine betaine
FCL46_RS09555	ENOG4108HQS	Glycine betaine
FCL46_RS09560	ENOG4105GIJ	Glycine betaine
FCL46_RS09590	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
FCL46_RS09595	ENOG4105BZU	Histidine kinase
FCL46_RS09610	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
FCL46_RS09625	ENOG4108EMV	Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity)
FCL46_RS09630	ENOG4108KPW	sugar kinase
FCL46_RS09635	ENOG4105CTQ	phosphohexokinase
FCL46_RS09660	ENOG4105DB7	PHP domain protein
FCL46_RS09665	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS09670	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
FCL46_RS09675	ENOG4105W49	UPF0434 protein
FCL46_RS09695	ENOG4105C3J	Cysteine desulfurase
FCL46_RS09705	ENOG4107QHF	type ii secretion system protein e
FCL46_RS09730	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
FCL46_RS09735	ENOG4108UJU	UPF0301 protein
FCL46_RS09745	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
FCL46_RS09750	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
FCL46_RS09755	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
FCL46_RS09760	ENOG4105CHW	UPF0052 protein
FCL46_RS09765	ENOG4105BZU	Histidine kinase
FCL46_RS09770	ENOG4105CQ7	ATP-dependent helicase
FCL46_RS09775	ENOG4105C25	Primosomal protein n'
FCL46_RS09780	ENOG4105BZU	Histidine kinase
FCL46_RS09790	ENOG4107R1I	NAD-dependent malic enzyme
FCL46_RS09795	ENOG4105VEQ	Cold shock protein
FCL46_RS09800	ENOG4108J2P	Alpha beta hydrolase fold
FCL46_RS09805	ENOG410680H	amp-dependent synthetase and ligase
FCL46_RS09810	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
FCL46_RS09815	ENOG4105ERG	peptidase m48, ste24p
FCL46_RS09820	ENOG4105DX0	Hemolysin A
FCL46_RS09830	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
FCL46_RS09840	ENOG4105SG9	biopolymer transport protein, ExbD
FCL46_RS09845	ENOG4105E02	MotA TolQ exbB proton channel
FCL46_RS09850	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
FCL46_RS09855	ENOG4105CHR	reductase
FCL46_RS09870	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FCL46_RS09875	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FCL46_RS09900	ENOG4105CJR	Integral membrane protein (MviN
FCL46_RS09905	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FCL46_RS09910	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
FCL46_RS09915	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
FCL46_RS09930	ENOG4105CJW	magnesium transporter
FCL46_RS09935	ENOG4105C0H	protease
FCL46_RS09945	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
FCL46_RS09960	ENOG4105C8T	Leucyl-tRNA synthetase
FCL46_RS09965	ENOG4105CDU	Replicative dna helicase
FCL46_RS09970	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
FCL46_RS09980	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
FCL46_RS09985	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
FCL46_RS09990	ENOG4108IY2	MazG family
FCL46_RS10000	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
FCL46_RS10005	ENOG4105K46	50S ribosomal protein l27
FCL46_RS10010	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FCL46_RS10015	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
FCL46_RS10020	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
FCL46_RS10025	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
FCL46_RS10030	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
FCL46_RS10035	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
FCL46_RS10040	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FCL46_RS10045	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
FCL46_RS10060	ENOG4105C03	ribonuclease
FCL46_RS10065	ENOG4105K64	Glycosyl transferase, family 2
FCL46_RS10075	ENOG4108UUM	single-stranded DNA-binding protein
FCL46_RS10080	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FCL46_RS10085	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FCL46_RS10090	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FCL46_RS10100	ENOG4105VEQ	Cold shock protein
FCL46_RS10105	ENOG4105K8N	protein family UPF0079, ATPase
FCL46_RS10110	ENOG4105DDY	UPF0142 protein ycaO
FCL46_RS10125	ENOG4108P62	biosynthesis protein (CbiG)
FCL46_RS10130	ENOG4105E4R	Precorrin-3B C17-methyltransferase
FCL46_RS10145	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
FCL46_RS10150	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
FCL46_RS10155	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
FCL46_RS10160	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
FCL46_RS10165	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
FCL46_RS10170	ENOG41081F0	Precorrin-8x methylmutase
FCL46_RS10175	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
FCL46_RS10180	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FCL46_RS10190	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
FCL46_RS10195	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
FCL46_RS10205	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
FCL46_RS10210	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FCL46_RS10215	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
FCL46_RS10220	ENOG4105CP9	extracellular ligand-binding receptor
FCL46_RS10225	ENOG4105C32	Amino acid ABC transporter (Permease)
FCL46_RS10230	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
FCL46_RS10235	ENOG4105C0Z	ABC transporter
FCL46_RS10240	ENOG4108IV0	ABC, transporter
FCL46_RS10250	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FCL46_RS10255	ENOG4105C98	muts2 protein
FCL46_RS10260	ENOG4108YBP	pseudouridine synthase
FCL46_RS10265	ENOG4107QQG	Dehydrogenase
FCL46_RS10275	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
FCL46_RS10280	ENOG4105C0P	Mg chelatase subunit ChlI
FCL46_RS10295	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
FCL46_RS10300	ENOG4107YWA	deoxycytidylate deaminase
FCL46_RS10310	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS10315	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS10335	ENOG4108I5C	dEAD DEAH box helicase
FCL46_RS10345	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
FCL46_RS10350	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
FCL46_RS10375	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
FCL46_RS10380	ENOG4105DF5	DNA topoisomerase IV, subunit A
FCL46_RS10385	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FCL46_RS10400	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
FCL46_RS10405	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
FCL46_RS10415	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
FCL46_RS10420	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
FCL46_RS10430	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
FCL46_RS10575	ENOG4105BZU	Histidine kinase
FCL46_RS10655	ENOG4107ZQV	short-chain dehydrogenase reductase
FCL46_RS10670	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FCL46_RS10680	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
FCL46_RS10695	ENOG4105BZU	Histidine kinase
FCL46_RS10705	ENOG4105C7K	acetolactate synthase
FCL46_RS10710	ENOG4108ZP8	Acetolactate synthase small subunit
FCL46_RS10725	ENOG4105BZU	Histidine kinase
FCL46_RS10735	ENOG4105BZU	Histidine kinase
FCL46_RS10770	ENOG4105DFD	Na H antiporter
FCL46_RS10780	ENOG4108JQ6	ABC transporter
FCL46_RS10785	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FCL46_RS10790	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
FCL46_RS10805	ENOG4108ESY	Metal dependent phosphohydrolase
FCL46_RS10815	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL46_RS10825	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
FCL46_RS10830	ENOG4107FQ9	ethanolamine ammonia-lyase
FCL46_RS10835	ENOG4105DYY	Reactivating factor for ethanolamine ammonia lyase
FCL46_RS10840	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FCL46_RS10850	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
FCL46_RS10855	ENOG4105TMB	Formate nitrite transporter
FCL46_RS10870	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
FCL46_RS10920	ENOG4106851	UPF0270 protein
FCL46_RS10940	ENOG4105EJQ	L-serine dehydratase
FCL46_RS10965	ENOG4105CHR	reductase
FCL46_RS10975	ENOG4108SHQ	Glutathione S-transferase
FCL46_RS10980	ENOG4105C8Y	Acetylornithine aminotransferase
FCL46_RS11020	ENOG4105CYW	agmatinase
FCL46_RS11025	ENOG4105D63	family UPF0324
FCL46_RS11040	ENOG4105C8Q	Methyl-accepting chemotaxis
FCL46_RS11065	ENOG4105Q9Y	Universal stress protein
FCL46_RS11075	ENOG4105CJW	magnesium transporter
FCL46_RS11090	ENOG4105C32	Amino acid ABC transporter (Permease)
FCL46_RS11100	ENOG4105C0Z	ABC transporter
FCL46_RS11105	ENOG4108IV0	ABC, transporter
FCL46_RS11110	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
FCL46_RS11120	ENOG4105KI2	Urea amidohydrolase subunit beta
FCL46_RS11125	ENOG4105CQM	Urea amidohydrolase subunit alpha
FCL46_RS11130	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
FCL46_RS11135	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
FCL46_RS11140	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
FCL46_RS11160	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS11170	ENOG4105EGS	Mechanosensitive ion channel
FCL46_RS11225	ENOG4105DQ6	Transposase
FCL46_RS11240	ENOG4105D7N	magnesium and cobalt transport protein CorA
FCL46_RS11245	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
FCL46_RS11260	ENOG4105CJW	magnesium transporter
FCL46_RS11265	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
FCL46_RS11275	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
FCL46_RS11280	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
FCL46_RS11285	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS11305	ENOG4105K4H	Nlp p60 protein
FCL46_RS11345	ENOG41085KW	ppic-type peptidyL-prolyl cis-trans isomerase
FCL46_RS11355	ENOG4105ENH	Sulfatase
FCL46_RS11370	ENOG4105BZU	Histidine kinase
FCL46_RS11375	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FCL46_RS11400	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
FCL46_RS11410	ENOG4105GVR	general secretion pathway protein D
FCL46_RS11470	ENOG4105D9P	serine threonine protein kinase
FCL46_RS11485	ENOG4105E4C	Lytic transglycosylase catalytic
FCL46_RS11505	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
FCL46_RS11540	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FCL46_RS11545	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FCL46_RS11555	ENOG4105CZE	histidine utilization repressor
FCL46_RS11565	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
FCL46_RS11600	ENOG4105DR9	pseudouridine synthase
FCL46_RS11610	ENOG4108UH6	UPF0754 membrane protein
FCL46_RS11615	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
FCL46_RS11635	ENOG4107WAP	fad NAD(P)-binding domain
FCL46_RS11650	ENOG4105CD8	aminopeptidase N
FCL46_RS11655	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
FCL46_RS11660	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
FCL46_RS11670	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL46_RS11675	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
FCL46_RS11680	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
FCL46_RS11685	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS11690	ENOG4105CQZ	Histidine kinase
FCL46_RS11700	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
FCL46_RS11710	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
FCL46_RS11715	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
FCL46_RS11725	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
FCL46_RS11730	ENOG4105K70	DNA-binding protein
FCL46_RS11745	ENOG4105CQC	Prephenate dehydratase
FCL46_RS11750	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FCL46_RS11760	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
FCL46_RS11765	ENOG4107QW4	alcohol dehydrogenase
FCL46_RS11785	ENOG4105F8J	Adenylate Guanylate cyclase
FCL46_RS11795	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
FCL46_RS11835	ENOG4107QY8	reductase
FCL46_RS11840	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
FCL46_RS11845	ENOG4105C5H	ABC transporter
FCL46_RS11855	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FCL46_RS11860	ENOG4105C12	Phosphoribosylglycinamide synthetase
FCL46_RS11865	ENOG4107Z3H	Transcriptional regulator, TetR family
FCL46_RS11870	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
FCL46_RS11885	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FCL46_RS11890	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
FCL46_RS11900	ENOG4108IV0	ABC, transporter
FCL46_RS11905	ENOG4105C0Z	ABC transporter
FCL46_RS11910	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
FCL46_RS11915	ENOG4105C32	Amino acid ABC transporter (Permease)
FCL46_RS11925	ENOG4105C26	Dehydrogenase
FCL46_RS11940	ENOG4105EB3	Histidine kinase
FCL46_RS11950	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS11965	ENOG410804T	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
FCL46_RS11980	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FCL46_RS11990	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
FCL46_RS11995	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
FCL46_RS12000	ENOG4107TEJ	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
FCL46_RS12005	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
FCL46_RS12010	ENOG4105CAK	Cell division ATP-binding protein ftsE
FCL46_RS12015	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
FCL46_RS12025	ENOG4105CN1	protease
FCL46_RS12030	ENOG4105VTS	DnaJ-like, subfamily C
FCL46_RS12040	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
FCL46_RS12045	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
FCL46_RS12065	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
FCL46_RS12070	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
FCL46_RS12080	ENOG4105EWC	Purine nucleoside phosphorylase
FCL46_RS12100	ENOG4105VB9	50S ribosomal protein l28
FCL46_RS12105	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
FCL46_RS12120	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
FCL46_RS12125	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
FCL46_RS12140	ENOG4105SVQ	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression (By similarity)
FCL46_RS12145	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FCL46_RS12150	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FCL46_RS12155	ENOG41084BP	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
FCL46_RS12160	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
FCL46_RS12165	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
FCL46_RS12170	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
FCL46_RS12180	ENOG4108FWV	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
FCL46_RS12205	ENOG4105D49	3-dehydroquinate synthase
FCL46_RS12210	ENOG4107RIQ	Sulfate adenylate transferase
FCL46_RS12215	ENOG4105C59	p-type ATPase
FCL46_RS12250	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS12255	ENOG4105BZU	Histidine kinase
FCL46_RS12335	ENOG4106855	Competence protein
FCL46_RS12355	ENOG4108RS6	transposase
FCL46_RS12390	ENOG4107QRS	glycosyltransferase group 2 family protein
FCL46_RS12395	ENOG4105JNK	Glycosyl transferase (Group 1
FCL46_RS12400	ENOG4105K64	Glycosyl transferase, family 2
FCL46_RS12405	ENOG4107YYJ	Glycosyl transferase, family 2
FCL46_RS12435	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
FCL46_RS12445	ENOG4105C8B	TIGR00159 family
FCL46_RS12475	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS12480	ENOG4108001	transporter AmpG 1
FCL46_RS12485	ENOG4105C8N	cysteinyl-tRNA synthetase
FCL46_RS12490	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
FCL46_RS12505	ENOG4105DFU	Cell wall formation (By similarity)
FCL46_RS12520	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
FCL46_RS12525	ENOG4105EM7	Selenocysteine-specific translation elongation factor
FCL46_RS12530	ENOG4105C5X	domain protein
FCL46_RS12535	ENOG4105D1F	ATP-binding protein
FCL46_RS12540	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FCL46_RS12550	ENOG4105CHM	Aminotransferase
FCL46_RS12555	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
FCL46_RS12565	ENOG4107Z36	nucleotidyl transferase
FCL46_RS12575	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FCL46_RS12580	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
FCL46_RS12585	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FCL46_RS12590	ENOG4105EHZ	conserved protein UCP016719
FCL46_RS12595	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
FCL46_RS12600	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
FCL46_RS12625	ENOG4105HHA	aminodeoxychorismate lyase
FCL46_RS12630	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
FCL46_RS12635	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
FCL46_RS12655	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
FCL46_RS12660	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
FCL46_RS12670	ENOG4105DQU	oxidoreductase, subunit beta
FCL46_RS12675	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
FCL46_RS12685	ENOG4105DRR	Transcriptional regulator, GntR family
FCL46_RS12690	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
FCL46_RS12695	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
FCL46_RS12710	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
FCL46_RS12715	ENOG4105K5B	UPF0225 protein
FCL46_RS12720	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
FCL46_RS12725	ENOG4105D3Q	Sugar transferase
FCL46_RS12730	ENOG4108KBE	Glycosyl transferase, family 2
FCL46_RS12745	ENOG4105CKK	Glycosyl transferase, family 2
FCL46_RS12775	ENOG4105K64	Glycosyl transferase, family 2
FCL46_RS12800	ENOG4105CKK	Glycosyl transferase, family 2
FCL46_RS12815	ENOG4106WTF	Glycosyl transferase, family 2
FCL46_RS12830	ENOG4108PQP	glycosyl transferase group 1
FCL46_RS12840	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
FCL46_RS12855	ENOG4105D2T	synthase
FCL46_RS12860	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
FCL46_RS12865	ENOG4105F0R	Cytidylyltransferase
FCL46_RS12870	ENOG4105C26	Dehydrogenase
FCL46_RS12875	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
FCL46_RS12880	ENOG4105ECJ	Glycosyl Transferase
FCL46_RS12905	ENOG4105CPK	Glycosyl transferase (Group 1
FCL46_RS12930	ENOG4105EY8	ABC transporter
FCL46_RS12950	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
FCL46_RS12955	ENOG4107STW	synthase
FCL46_RS12960	ENOG4108SHN	Glycosyl transferase, family 2
FCL46_RS12980	ENOG4105EY8	ABC transporter
FCL46_RS12995	ENOG4105BZ1	(ABC) transporter
FCL46_RS13000	ENOG4105PF3	O-Antigen polymerase
FCL46_RS13005	ENOG4105BZU	Histidine kinase
FCL46_RS13015	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
FCL46_RS13020	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
FCL46_RS13025	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
FCL46_RS13030	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
FCL46_RS13040	ENOG4108V3W	Chemotaxis protein, CheW
FCL46_RS13045	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
FCL46_RS13050	ENOG4105BZU	Histidine kinase
FCL46_RS13055	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS13070	ENOG4105EYW	Ion transport protein
FCL46_RS13075	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS13100	ENOG4108VYJ	response regulator receiver protein
FCL46_RS13110	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
FCL46_RS13115	ENOG4108ZC9	flagellar basal-body rod protein flgc
FCL46_RS13120	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
FCL46_RS13125	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
FCL46_RS13130	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
FCL46_RS13160	ENOG4105W00	Flagellar hook capping protein
FCL46_RS13165	ENOG4105BZE	flagellar hook protein, FlgE
FCL46_RS13170	ENOG4105E14	MotA TolQ exbB proton channel
FCL46_RS13175	ENOG4105ER2	Ompa motb domain protein
FCL46_RS13180	ENOG4105X6C	Flagellar basal body-associated protein FliL
FCL46_RS13190	ENOG4105DD5	Flagellar motor switch protein
FCL46_RS13200	ENOG4105CN7	Flagellar biosynthetic protein FliP
FCL46_RS13205	ENOG4105VS8	Flagellar biosynthetic protein fliq
FCL46_RS13210	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
FCL46_RS13215	ENOG4105D00	flagellar biosynthetic protein flhB
FCL46_RS13220	ENOG4105D7B	Flagellar biosynthesis protein flha
FCL46_RS13225	ENOG4105FZW	flagellar biosynthesis regulator FlhF
FCL46_RS13235	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FCL46_RS13245	ENOG4108JQA	flagellar
FCL46_RS13250	ENOG4105CGA	flagellar basal-body rod protein FlgG
FCL46_RS13260	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
FCL46_RS13265	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
FCL46_RS13270	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
FCL46_RS13275	ENOG4105CQZ	Histidine kinase
FCL46_RS13300	ENOG4105CGA	flagellar basal-body rod protein FlgG
FCL46_RS13310	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
FCL46_RS13315	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
FCL46_RS13320	ENOG4105I03	Flagellin
FCL46_RS13335	ENOG4105I03	Flagellin
FCL46_RS13350	ENOG4107RT6	flagellar hook-associated
FCL46_RS13395	ENOG4105QAS	Iron-sulfur cluster assembly accessory protein
FCL46_RS13405	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
FCL46_RS13445	ENOG4105EWK	phytoene
FCL46_RS13465	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FCL46_RS13480	ENOG4105BZU	Histidine kinase
FCL46_RS13485	ENOG4105DF6	Fe-S oxidoreductase
FCL46_RS13510	ENOG4105C8Q	Methyl-accepting chemotaxis
FCL46_RS13530	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
FCL46_RS13535	ENOG41080XS	Cobyrinic acid ac-diamide synthase
FCL46_RS13545	ENOG4107VP5	methyltetrahydrofolate corrinoid iron-sulfur protein methyltransferase
FCL46_RS13550	ENOG4105EYX	Acetyl-CoA decarbonylase synthase complex subunit gamma
FCL46_RS13555	ENOG4105E8X	CO dehydrogenase acetyl-CoA synthase complex beta subunit
FCL46_RS13560	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
FCL46_RS13565	ENOG4106HYN	CO dehydrogenase acetyl-CoA synthase delta subunit
FCL46_RS13580	ENOG4108RAC	Rubrerythrin
FCL46_RS13595	ENOG4105C28	cystathionine
FCL46_RS13605	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
FCL46_RS13610	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FCL46_RS13615	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
FCL46_RS13620	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
FCL46_RS13630	ENOG4107QN1	sodium solute
FCL46_RS13640	ENOG4105CYC	Transferase
FCL46_RS13655	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
FCL46_RS13660	ENOG4105C1G	acyl-Coa dehydrogenase
FCL46_RS13665	ENOG4105E39	Enoyl-CoA hydratase
FCL46_RS13675	ENOG4105DC7	peptidase M24
FCL46_RS13680	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
FCL46_RS13685	ENOG4105CHU	acetyl-coa acetyltransferase
FCL46_RS13690	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FCL46_RS13695	ENOG4105C1G	acyl-Coa dehydrogenase
FCL46_RS13700	ENOG4105BZJ	Electron transfer flavoprotein
FCL46_RS13705	ENOG4105C10	Electron transfer flavoprotein
FCL46_RS13710	ENOG4107Z3H	Transcriptional regulator, TetR family
FCL46_RS13715	ENOG4105D5P	Methylmalonyl-coA mutase
FCL46_RS13725	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
FCL46_RS13730	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
FCL46_RS13735	ENOG4105ENH	Sulfatase
FCL46_RS13750	ENOG4106HWW	Acyltransferase family
FCL46_RS13755	ENOG4108IJ9	(ABC) transporter
FCL46_RS13760	ENOG4105CHM	Aminotransferase
FCL46_RS13765	ENOG4105EJQ	L-serine dehydratase
FCL46_RS13770	ENOG4105D0C	transport protein
FCL46_RS13775	ENOG4105FE9	pseudouridine synthase
FCL46_RS13790	ENOG4107SFQ	iron-sulfur binding
FCL46_RS13810	ENOG4105KIP	Thioesterase
FCL46_RS13830	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
FCL46_RS13840	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
FCL46_RS13855	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS13860	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
FCL46_RS13865	ENOG4105DAN	ATP-dependent protease
FCL46_RS13880	ENOG4105C8Q	Methyl-accepting chemotaxis
FCL46_RS13885	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
FCL46_RS13890	ENOG4105EWT	decarboxylase family
FCL46_RS13895	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
FCL46_RS13910	ENOG4105EPR	degv family
FCL46_RS13915	ENOG4105CDA	abc transporter atp-binding protein
FCL46_RS13920	ENOG4105DRP	amino acid AbC transporter
FCL46_RS13925	ENOG4105EZ7	amino acid ABC transporter
FCL46_RS13930	ENOG4107QXX	ABC transporter
FCL46_RS13935	ENOG4107RP9	extracellular solute-binding protein, family 3
FCL46_RS13940	ENOG4105E5Q	amino acid AbC transporter
FCL46_RS13945	ENOG4105E5Q	amino acid AbC transporter
FCL46_RS13950	ENOG4105CDA	abc transporter atp-binding protein
FCL46_RS13960	ENOG4105S0E	allantoin catabolism protein
FCL46_RS13965	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
FCL46_RS13990	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
FCL46_RS14010	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
FCL46_RS14015	ENOG4105EYW	Ion transport protein
FCL46_RS14040	ENOG4105BZU	Histidine kinase
FCL46_RS14045	ENOG4105EFI	regulatoR
FCL46_RS14050	ENOG4107QY8	reductase
FCL46_RS14055	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
FCL46_RS14085	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS14095	ENOG4105CCS	Glutamate formiminotransferase
FCL46_RS14100	ENOG4105CI2	imidazolone-5-propionate hydrolase
FCL46_RS14105	ENOG4105CGP	Urocanate hydratase
FCL46_RS14110	ENOG4105C84	Histidine ammonia-lyase
FCL46_RS14115	ENOG4105CZE	histidine utilization repressor
FCL46_RS14120	ENOG4105VRT	cytoplasmic protein
FCL46_RS14175	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
FCL46_RS14180	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
FCL46_RS14185	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
FCL46_RS14190	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
FCL46_RS14205	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
FCL46_RS14210	ENOG4105C9A	Phoh family
FCL46_RS14215	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
FCL46_RS14270	ENOG4105IBP	Cyclic peptide transporter
FCL46_RS14275	ENOG4108HM4	ABC transporter
FCL46_RS14310	ENOG4107UBR	Extracellular solute-binding protein family 3
FCL46_RS14325	ENOG4105K6T	rare lipoprotein A
FCL46_RS14330	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
FCL46_RS14335	ENOG4105DK0	Indole-3-glycerol phosphate synthase
FCL46_RS14340	ENOG4107QYG	anthranilate phosphoribosyltransferase
FCL46_RS14345	ENOG4105DDQ	anthranilate synthase
FCL46_RS14350	ENOG4105CRQ	synthase (Component I)
FCL46_RS14355	ENOG4108317	Binds directly to 16S ribosomal RNA (By similarity)
FCL46_RS14365	ENOG4105CFP	Peptidase U32
FCL46_RS14370	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
FCL46_RS14375	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
FCL46_RS14380	ENOG4105DC1	bifunctional purine biosynthesis protein purh
FCL46_RS14385	ENOG4105VEJ	Heat shock protein
FCL46_RS14390	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
FCL46_RS14405	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FCL46_RS14425	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
FCL46_RS14440	ENOG4105C8Q	Methyl-accepting chemotaxis
FCL46_RS14445	ENOG4105D8X	mechanosensitive ion channel
FCL46_RS14495	ENOG4108BUD	transposase
FCL46_RS14500	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
FCL46_RS14520	ENOG4105C5I	Dehydrogenase
FCL46_RS14530	ENOG4107TT5	NLP P60 protein
FCL46_RS14535	ENOG4105N42	UPF0307 protein
FCL46_RS14540	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FCL46_RS14550	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
FCL46_RS14555	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
FCL46_RS14570	ENOG4105BZU	Histidine kinase
FCL46_RS14575	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
FCL46_RS14580	ENOG4108JQ5	ABC transporter
FCL46_RS14585	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
FCL46_RS14590	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
FCL46_RS14615	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
FCL46_RS14620	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
FCL46_RS14625	ENOG4105CZX	twitching motility protein
FCL46_RS14630	ENOG4108URH	decarboxylase
FCL46_RS14640	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
FCL46_RS14685	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS14705	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FCL46_RS14715	ENOG4105BZU	Histidine kinase
FCL46_RS14720	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS14735	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FCL46_RS14750	ENOG4105CTQ	phosphohexokinase
FCL46_RS14765	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
FCL46_RS14775	ENOG41085EG	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
FCL46_RS14780	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
FCL46_RS14785	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
FCL46_RS14790	ENOG4105DPN	Oligoendopeptidase f
FCL46_RS14795	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS14800	ENOG4108Z6B	deaminase
FCL46_RS14815	ENOG4105C6E	dna polymerase iii
FCL46_RS14820	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
FCL46_RS14825	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
FCL46_RS14835	ENOG4105C22	threonyL-tRNA synthetase
FCL46_RS14840	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
FCL46_RS14845	ENOG4105VJV	50s ribosomal protein L35
FCL46_RS14850	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
FCL46_RS14855	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
FCL46_RS14860	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
FCL46_RS14865	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
FCL46_RS14880	ENOG4108C33	Resolvase
FCL46_RS14910	ENOG4108CHM	Preferentially cleaves peptide bonds on the carboxyl- terminal side of aspartate and glutamate. Along with other extracellular proteases it is involved in colonization and infection of human tissues. Required for proteolytic maturation of thiol protease SspB and inactivation of SspC, an inhibitor of SspB. It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A, which are involved in adherence to host cells. May also protect bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG, IgA and IgM. May be involved in the stability of secreted lipases
FCL46_RS15010	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FCL46_RS15015	ENOG41084GC	stage II sporulation protein
FCL46_RS15035	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
FCL46_RS15040	ENOG4105CBT	Fructose-1,6-bisphosphatase
FCL46_RS15050	ENOG4105DPX	Hydrogenase, large subunit
FCL46_RS15060	ENOG4105BZU	Histidine kinase
FCL46_RS15065	ENOG4107RZH	Nitrite and sulphite reductase 4Fe-4S region
FCL46_RS15070	ENOG4106VK6	Flagellar motor protein
FCL46_RS15075	ENOG4107R0U	MotA TolQ exbB proton channel
FCL46_RS15080	ENOG4105C3F	Signal peptidase i
FCL46_RS15105	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
FCL46_RS15115	ENOG4105RD8	TRAP dicarboxylate transporter
FCL46_RS15125	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL46_RS15140	ENOG4107RCW	fructose-bisphosphate aldolase
FCL46_RS15145	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FCL46_RS15160	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FCL46_RS15165	ENOG4105D0M	Protease HtpX homolog
FCL46_RS15180	ENOG4105MYT	Heat shock protein
FCL46_RS15275	ENOG4107EFR	Flavocytochrome c
FCL46_RS15290	ENOG4105VNH	ABC transporter solute-binding protein
FCL46_RS15300	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
FCL46_RS15310	ENOG41064T2	transcriptional regulator, lysR family
FCL46_RS15315	ENOG4105JVC	membrAne
FCL46_RS15335	ENOG4105C3M	thioredoxin reductase
FCL46_RS15340	ENOG4105K63	Thioredoxin
FCL46_RS15345	ENOG4108MR7	Arylsulfotransferase
FCL46_RS15365	ENOG41061ZR	Transcriptional regulator
FCL46_RS15370	ENOG4105D8X	mechanosensitive ion channel
FCL46_RS15385	ENOG41080WF	Electron transport complex, RnfABCDGE type, G subunit
FCL46_RS15435	ENOG4107R1I	NAD-dependent malic enzyme
FCL46_RS15440	ENOG4105DZS	Phenylacetate-CoA ligase
FCL46_RS15450	ENOG4105DZS	Phenylacetate-CoA ligase
FCL46_RS15465	ENOG4105W87	Cbs domain
FCL46_RS15470	ENOG4107QZM	n-acetylglutamate synthase
FCL46_RS15490	ENOG4105C19	ABC transporter
FCL46_RS15510	ENOG4105C5H	ABC transporter
FCL46_RS15520	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
FCL46_RS15545	ENOG4105DWV	Homoserine O-trans-acetylase
FCL46_RS15550	ENOG4105DTA	methyltransferase
FCL46_RS15555	ENOG4105D7W	serine acetyltransferase
FCL46_RS15560	ENOG4105C6T	cysteine synthase
FCL46_RS15570	ENOG4105DUM	transcriptional regulator, lysR family
FCL46_RS15575	ENOG4105Q84	sucrose synthase
FCL46_RS15585	ENOG4107QHF	type ii secretion system protein e
FCL46_RS15590	ENOG4105GVR	general secretion pathway protein D
FCL46_RS15635	ENOG4108VAU	general secretion pathway protein G
FCL46_RS15645	ENOG4105D7Q	type ii secretion system
FCL46_RS15665	ENOG4105BZU	Histidine kinase
FCL46_RS15670	ENOG4107TFB	basic membrane
FCL46_RS15675	ENOG4107TFB	basic membrane
FCL46_RS15695	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL46_RS15700	ENOG4105CPD	ethanolamine ammonia-lyase
FCL46_RS15705	ENOG4107FQ9	ethanolamine ammonia-lyase
FCL46_RS15725	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
FCL46_RS15730	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
FCL46_RS15735	ENOG4105CNN	ABC, transporter
FCL46_RS15740	ENOG41071MT	Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane
FCL46_RS15745	ENOG4105C2J	ABC transporter
FCL46_RS15750	ENOG4105D4B	ABC, transporter
FCL46_RS15755	ENOG4105C9J	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde (By similarity)
FCL46_RS15760	ENOG4105DKG	l-rhamnose isomerase
FCL46_RS15765	ENOG4105DET	Rhamnulokinase
FCL46_RS15775	ENOG4107EFR	Flavocytochrome c
FCL46_RS15780	ENOG4107EFR	Flavocytochrome c
FCL46_RS15795	ENOG4105CYC	Transferase
FCL46_RS15845	ENOG4105EMU	Dehydrogenase
FCL46_RS15880	ENOG4107QQB	Ribonuclease E
FCL46_RS15885	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
FCL46_RS15895	ENOG4105CVE	Lytic murein transglycosylase
FCL46_RS15910	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
FCL46_RS15915	ENOG4105E2X	shikimate dehydrogenase
FCL46_RS15920	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
FCL46_RS15925	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
FCL46_RS15945	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
FCL46_RS15970	ENOG4105CN1	protease
FCL46_RS15985	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
FCL46_RS15990	ENOG4105CRE	cytochrome C
FCL46_RS15995	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
FCL46_RS16005	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
FCL46_RS16015	ENOG4107QX9	Thiol disulfide interChange protein
FCL46_RS16020	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
FCL46_RS16030	ENOG410826D	Involved in DNA repair and RecF pathway recombination (By similarity)
FCL46_RS16060	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
FCL46_RS16065	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
FCL46_RS16075	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
FCL46_RS16080	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
FCL46_RS16090	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FCL46_RS16105	ENOG4105BZM	domain protein
FCL46_RS16115	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
FCL46_RS16130	ENOG4108IJ9	(ABC) transporter
FCL46_RS16135	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FCL46_RS16145	ENOG4105C8Q	Methyl-accepting chemotaxis
FCL46_RS16150	ENOG4105BZU	Histidine kinase
FCL46_RS16155	ENOG4105BZU	Histidine kinase
FCL46_RS16170	ENOG4107Z3H	Transcriptional regulator, TetR family
FCL46_RS16175	ENOG410624X	efflux transporter, rnd family, mfp subunit
FCL46_RS16195	ENOG4105BZU	Histidine kinase
FCL46_RS16210	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FCL46_RS16225	ENOG4105DQ6	Transposase
FCL46_RS16235	ENOG4105C1G	acyl-Coa dehydrogenase
FCL46_RS16240	ENOG4105FCD	Major Facilitator
FCL46_RS16250	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
FCL46_RS16265	ENOG4105C10	Electron transfer flavoprotein
FCL46_RS16270	ENOG4105TPV	
FCL46_RS16275	ENOG4105DF6	Fe-S oxidoreductase
FCL46_RS16280	ENOG4105D2S	major facilitator superfamily
FCL46_RS16290	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
FCL46_RS16305	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
FCL46_RS16325	ENOG4105BZU	Histidine kinase
FCL46_RS16355	ENOG4108V06	Glutathione peroxidase
FCL46_RS16385	ENOG4105CGD	Nad-dependent epimerase dehydratase
FCL46_RS16395	ENOG4108RZE	Tetr family transcriptional regulator
FCL46_RS16405	ENOG4107Z6I	Thiamine biosynthesis protein
FCL46_RS16410	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
FCL46_RS16415	ENOG4108YI8	ABC transporter
FCL46_RS16420	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
FCL46_RS16425	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
FCL46_RS16430	ENOG4107PBV	potassium channel
FCL46_RS16445	ENOG4107RUY	(E1 component), alpha subunit
FCL46_RS16450	ENOG4105CPP	Dehydrogenase, E1 component
FCL46_RS16455	ENOG4105C7S	Dehydrogenase
FCL46_RS16460	ENOG4107QN2	dihydrolipoyl dehydrogenase
FCL46_RS16465	ENOG4105D82	Glutamate dehydrogenase
FCL46_RS16475	ENOG4105D5P	Methylmalonyl-coA mutase
FCL46_RS16500	ENOG4105C5H	ABC transporter
FCL46_RS16505	ENOG4105C5H	ABC transporter
FCL46_RS16510	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
FCL46_RS16515	ENOG4105E0C	molybdate abc transporter
FCL46_RS16520	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
FCL46_RS16525	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
FCL46_RS16535	ENOG4108Z0Z	intracellular protease Pfpi family
FCL46_RS16555	ENOG4105C1J	atp-dependent rna helicase
FCL46_RS16565	ENOG4105I03	Flagellin
FCL46_RS16615	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
FCL46_RS16620	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS16640	ENOG4105QAX	Iron-sulfur
FCL46_RS16655	ENOG4105DT3	PTS system, galactitol-specific IIc component
FCL46_RS16670	ENOG4105D7N	magnesium and cobalt transport protein CorA
FCL46_RS16675	ENOG4107TPS	domain protein
FCL46_RS16695	ENOG4105C8B	TIGR00159 family
FCL46_RS16735	ENOG4107V40	secretion protein, HlyD family
FCL46_RS16755	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL46_RS16765	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
FCL46_RS16775	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS16780	ENOG4105CQZ	Histidine kinase
FCL46_RS16790	ENOG4105H1G	trap transporter solute receptor taxi family
FCL46_RS16800	ENOG4105CQB	FAD linked oxidase domain protein
FCL46_RS16810	ENOG4105C94	Transporter
FCL46_RS16815	ENOG4105ETT	transcriptional Regulator, LysR family
FCL46_RS16820	ENOG4108IJ0	Aspartate ammonia-lyase
FCL46_RS16830	ENOG4105CPC	Aldo Keto reductase
FCL46_RS16835	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
FCL46_RS16840	ENOG4105C26	Dehydrogenase
FCL46_RS16845	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
FCL46_RS16855	ENOG4105C6N	Formate acetyltransferase
FCL46_RS16860	ENOG4105BZU	Histidine kinase
FCL46_RS16865	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS16875	ENOG4105C2C	drug resistance transporter, Bcr CflA
FCL46_RS16880	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL46_RS16890	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
FCL46_RS16900	ENOG4107QWJ	nitrate reductase beta subunit
FCL46_RS16905	ENOG4108J2R	molybdopterin oxidoreductase
FCL46_RS16920	ENOG4105NBK	UPF0345 protein
FCL46_RS16925	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
FCL46_RS16940	ENOG4105FUX	Conserved Protein
FCL46_RS16945	ENOG4108P9J	Phage shock protein A
FCL46_RS16950	ENOG4107VNS	Protein of unknown function (DUF2491)
FCL46_RS16960	ENOG4105F1G	UPF0441 protein
FCL46_RS16965	ENOG4106032	Glutathionylspermidine synthase
FCL46_RS16980	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
FCL46_RS16985	ENOG4105C1A	potassium transporter peripheral membrane
FCL46_RS16990	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
FCL46_RS16995	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FCL46_RS17000	ENOG4108JPZ	Monovalent cation H antiporter subunit D
FCL46_RS17015	ENOG4108JPZ	Monovalent cation H antiporter subunit D
FCL46_RS17110	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS17115	ENOG4105BZU	Histidine kinase
FCL46_RS17120	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
FCL46_RS17125	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FCL46_RS17130	ENOG4106KE4	Dehydrogenase
FCL46_RS17135	ENOG4105BZU	Histidine kinase
FCL46_RS17155	ENOG4107T4Z	adenosine kinase
FCL46_RS17160	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
FCL46_RS17170	ENOG4108IPT	Naphthoate synthase
FCL46_RS17175	ENOG4107QX3	carboxylase
FCL46_RS17180	ENOG4105C1G	acyl-Coa dehydrogenase
FCL46_RS17195	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
FCL46_RS17205	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
FCL46_RS17210	ENOG4105ECP	epimerase
FCL46_RS17220	ENOG4105PTV	Nudix Hydrolase
FCL46_RS17275	ENOG4105CP7	Triose-phosphate isomerase
FCL46_RS17280	ENOG4105BZA	Phosphoglycerate kinase
FCL46_RS17285	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
FCL46_RS17290	ENOG4108IJ9	(ABC) transporter
FCL46_RS17295	ENOG4108IJ9	(ABC) transporter
FCL46_RS17305	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
FCL46_RS17320	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
FCL46_RS17340	ENOG4105C8P	)-transporter
FCL46_RS17345	ENOG4105CA9	Pyruvate kinase
FCL46_RS17360	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
FCL46_RS17365	ENOG4107X42	5-methylthioadenosine S-adenosylhomocysteine nucleosidase
FCL46_RS17390	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
FCL46_RS17400	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
FCL46_RS17440	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FCL46_RS17445	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FCL46_RS17450	ENOG4105EEQ	Na H antiporter
FCL46_RS17460	ENOG4108HMN	Caspase domain
FCL46_RS17490	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
FCL46_RS17495	ENOG4108MJI	response regulator
FCL46_RS17530	ENOG4105BZS	acriflavin resistance protein
FCL46_RS17535	ENOG4106HB6	Alpha beta hydrolase
FCL46_RS17545	ENOG4106TD9	Diguanylate cyclase
FCL46_RS17600	ENOG4105DRR	Transcriptional regulator, GntR family
FCL46_RS17640	ENOG4108YBP	pseudouridine synthase
FCL46_RS17645	ENOG4105C1J	atp-dependent rna helicase
FCL46_RS17660	ENOG4105WH1	Two component transcriptional regulator luxr family
FCL46_RS17665	ENOG4105ENE	Histidine kinase
FCL46_RS17670	ENOG4108HWW	ABC transporter
FCL46_RS17680	ENOG4105DFW	ABC transporter
FCL46_RS17685	ENOG4105E2R	ROK family
FCL46_RS17695	ENOG4105CMG	Carbohydrate kinase
FCL46_RS17700	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
FCL46_RS17720	ENOG4105CHH	sulfate transporter
FCL46_RS17725	ENOG4108W15	Protein of unknown function (DUF1456)
FCL46_RS17730	ENOG4108JJB	ABC transporter
FCL46_RS17735	ENOG4105C7J	ABC transporter, permease
FCL46_RS17745	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
FCL46_RS17765	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
FCL46_RS17775	ENOG4105UQX	Mate efflux family protein
FCL46_RS17780	ENOG4107YTP	response regulator receiver protein
FCL46_RS17785	ENOG4105I7M	spermidine synthase
FCL46_RS17795	ENOG4105E27	serine threonine protein kinase
FCL46_RS17805	ENOG4105D3G	Pseudouridine synthase
FCL46_RS17815	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
FCL46_RS17825	ENOG4105E0Y	RtcB Protein
FCL46_RS17845	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FCL46_RS17850	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
FCL46_RS17875	ENOG4108YZN	class I peptide chain release factor
FCL46_RS17880	ENOG4107QI6	Cysteine desulfurase
FCL46_RS17915	ENOG4107EMZ	glycosyl transferase family
FCL46_RS17925	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
FCL46_RS17940	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
FCL46_RS17960	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FCL46_RS17965	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FCL46_RS17975	ENOG4105BZU	Histidine kinase
FCL46_RS18055	ENOG41090A1	ferritin
FCL46_RS18065	ENOG4105C4M	(Ubiquinol oxidase) subunit I
FCL46_RS18070	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
FCL46_RS18080	ENOG4105CC5	ABC transporter
FCL46_RS18085	ENOG4105DIK	(ABC) transporter
FCL46_RS18105	ENOG4105DRP	amino acid AbC transporter
FCL46_RS18110	ENOG4107R0W	ABC transporter
FCL46_RS18120	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FCL46_RS18125	ENOG4105CPQ	Dehydrogenase
FCL46_RS18130	ENOG4105BZU	Histidine kinase
FCL46_RS18140	ENOG4107R7I	amino acid
FCL46_RS18150	ENOG4105CC5	ABC transporter
FCL46_RS18155	ENOG4105FDK	ABC transporter
FCL46_RS18160	ENOG4107XSR	periplasmic solute binding protein
FCL46_RS18195	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
FCL46_RS18200	ENOG4105BZU	Histidine kinase
FCL46_RS18210	ENOG4108YZA	Nitrogen regulatory protein pii
FCL46_RS18225	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
FCL46_RS18245	ENOG41066FR	extracellular solute-binding protein
FCL46_RS18255	ENOG4105EAC	phosphoserine phosphatase
FCL46_RS18260	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
FCL46_RS18265	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FCL46_RS18275	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
FCL46_RS18280	ENOG4108TGP	Thioesterase superfamily protein
FCL46_RS18290	ENOG4105C10	Electron transfer flavoprotein
FCL46_RS18295	ENOG4105BZJ	Electron transfer flavoprotein
FCL46_RS18300	ENOG4105DF6	Fe-S oxidoreductase
FCL46_RS18305	ENOG4105C1G	acyl-Coa dehydrogenase
FCL46_RS18325	ENOG4107QSA	Oxaloacetate decarboxylase
FCL46_RS18330	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FCL46_RS18370	ENOG4105EN6	Membrane
FCL46_RS18385	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
FCL46_RS18400	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
FCL46_RS18425	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FCL46_RS18435	ENOG4105C1G	acyl-Coa dehydrogenase
FCL46_RS18440	ENOG4105CHU	acetyl-coa acetyltransferase
FCL46_RS18455	ENOG4105CHU	acetyl-coa acetyltransferase
FCL46_RS18460	ENOG4107XW0	Spermidine putrescine ABC transporter periplasmic spermidine putrescine-binding protein
FCL46_RS18465	ENOG4105BZU	Histidine kinase
FCL46_RS18470	ENOG4108Z66	YbaK ebsC protein
FCL46_RS18475	ENOG4108UQV	Membrane
FCL46_RS18500	ENOG4105Q9Y	Universal stress protein
FCL46_RS18520	ENOG4105WH1	Two component transcriptional regulator luxr family
FCL46_RS18530	ENOG41063TF	transcriptional regulator (AraC
FCL46_RS18535	ENOG4108W2Y	isochorismatase
FCL46_RS18540	ENOG4105C1J	atp-dependent rna helicase
FCL46_RS18545	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS18560	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS18570	ENOG410812K	response regulator receiver protein
FCL46_RS18575	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FCL46_RS18590	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS18600	ENOG4106PMH	Extracellular solute-binding protein family 3
FCL46_RS18605	ENOG4105E39	Enoyl-CoA hydratase
FCL46_RS18630	ENOG4105K63	Thioredoxin
FCL46_RS18695	ENOG4105KNY	Microcompartments protein
FCL46_RS18700	ENOG4105C0A	alcohol dehydrogenase
FCL46_RS18705	ENOG4105C6N	Formate acetyltransferase
FCL46_RS18710	ENOG4105F1A	Pyruvate formate-lyase
FCL46_RS18715	ENOG4105KNY	Microcompartments protein
FCL46_RS18720	ENOG4105C0A	alcohol dehydrogenase
FCL46_RS18725	ENOG4105KNY	Microcompartments protein
FCL46_RS18730	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
FCL46_RS18735	ENOG4107YMV	ethanolamine utilization protein
FCL46_RS18745	ENOG4105WVM	ethanolamine utilization protein EutN carboxysome structural protein Ccml
FCL46_RS18760	ENOG4105KNY	Microcompartments protein
FCL46_RS18770	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
FCL46_RS18780	ENOG4105M3W	utilization protein
FCL46_RS18785	ENOG4105KTW	ethanolamine utilization protein
FCL46_RS18810	ENOG4105BZU	Histidine kinase
FCL46_RS18860	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
FCL46_RS18865	ENOG4107SJI	Dehydrogenase
FCL46_RS18870	ENOG4105CD3	dihydroorotase
FCL46_RS18875	ENOG4105C26	Dehydrogenase
FCL46_RS18880	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
FCL46_RS18885	ENOG4108JPW	Aminotransferase
FCL46_RS18890	ENOG4105EW9	transcriptional regulator AsnC family
FCL46_RS18895	ENOG4107YZX	Universal stress protein
FCL46_RS18945	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
FCL46_RS18950	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
FCL46_RS18955	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
FCL46_RS18980	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
FCL46_RS18985	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
FCL46_RS19005	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
FCL46_RS19080	ENOG4108JQC	penicillin-binding protein 1A
FCL46_RS19085	ENOG4105K4T	epimerase
FCL46_RS19090	ENOG4105VW4	glutaredoxin 3
FCL46_RS19105	ENOG4105Y7M	Transcriptional regulator, TetR family
FCL46_RS19110	ENOG41088CC	tellurite resistance protein tehB
FCL46_RS19120	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
FCL46_RS19200	ENOG4105DHT	Metal Dependent Phosphohydrolase
FCL46_RS19215	ENOG4105BZS	acriflavin resistance protein
FCL46_RS19220	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
FCL46_RS19225	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
FCL46_RS19245	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FCL46_RS19250	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FCL46_RS19255	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FCL46_RS19260	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FCL46_RS19265	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FCL46_RS19270	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
FCL46_RS19285	ENOG4105DCF	alanine dehydrogenase
FCL46_RS19320	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
FCL46_RS19325	ENOG4108JU5	Magnesium and cobalt efflux protein
FCL46_RS19330	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FCL46_RS19335	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
FCL46_RS19345	ENOG4107SA6	carbon-phosphorus lyase complex accessory protein
FCL46_RS19385	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
FCL46_RS19395	ENOG4105BZ8	glutamate synthase
FCL46_RS19400	ENOG4105CBC	glutamate synthase
FCL46_RS19405	ENOG4107TFB	basic membrane
FCL46_RS19410	ENOG4107TFB	basic membrane
FCL46_RS19435	ENOG4105CQS	hydrogenase expression formation protein HypD
FCL46_RS19475	ENOG4105CMR	udp-glucose 4-epimerase
FCL46_RS19530	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
FCL46_RS19545	ENOG4105C5W	Aldolase
FCL46_RS19550	ENOG4105D9P	serine threonine protein kinase
FCL46_RS19560	ENOG4105C5H	ABC transporter
FCL46_RS19565	ENOG4105DR5	peptidase
FCL46_RS19585	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
FCL46_RS19590	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
FCL46_RS19595	ENOG4105C0D	helicase
FCL46_RS19610	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
FCL46_RS19615	ENOG4105D6E	homoserine dehydrogenase
FCL46_RS19620	ENOG4105E3H	phosphoglycerate mutase
FCL46_RS19625	ENOG4107YD3	Thioesterase
FCL46_RS19645	ENOG4105CFP	Peptidase U32
FCL46_RS19655	ENOG4105UQX	Mate efflux family protein
FCL46_RS19665	ENOG4108HRK	Histidine kinase
FCL46_RS19670	ENOG4105DY9	regulatoR
FCL46_RS19685	ENOG4105CNW	domain protein
FCL46_RS19705	ENOG4105DCF	alanine dehydrogenase
FCL46_RS19710	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
FCL46_RS19715	ENOG4105HM0	Sulfoacetaldehyde acetyltransferase
FCL46_RS19720	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL46_RS19725	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
FCL46_RS19730	ENOG4105GQU	Trap dicarboxylate transporter, dctp subunit
FCL46_RS19735	ENOG4105CIF	Ornithine Cyclodeaminase
FCL46_RS19750	ENOG4105DDR	sarcosine oxidase (Beta subunit)
FCL46_RS19855	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
FCL46_RS19860	ENOG4108U5N	UPF0316 protein
FCL46_RS19880	ENOG4105CDV	Ompa motb domain protein
FCL46_RS19885	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
FCL46_RS19920	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
FCL46_RS19925	ENOG4108MRH	transcriptional regulatory protein
FCL46_RS19930	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
FCL46_RS19940	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
FCL46_RS19985	ENOG4105D03	DNA-3-methyladenine glycosylase II
FCL46_RS19990	ENOG4105K8R	UPF0145 protein
FCL46_RS20015	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FCL46_RS20030	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
FCL46_RS20055	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FCL46_RS20060	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FCL46_RS20065	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
FCL46_RS20070	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
FCL46_RS20075	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
FCL46_RS20080	ENOG41082J7	Rhodanese domain protein
FCL46_RS20085	ENOG4105C1J	atp-dependent rna helicase
FCL46_RS20095	ENOG4105CZX	twitching motility protein
FCL46_RS20100	ENOG4105C01	Dihydroxy-acid dehydratase
FCL46_RS20110	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
FCL46_RS20140	ENOG4105C8Q	Methyl-accepting chemotaxis
FCL46_RS20145	ENOG4105TQK	DNA polymerase iii, delta' subunit
FCL46_RS20150	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
FCL46_RS20155	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FCL46_RS20160	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
FCL46_RS20165	ENOG4107YU2	histidine triad (hIT) protein
FCL46_RS20170	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
FCL46_RS20175	ENOG4105CGY	Dna recombination protein
FCL46_RS20190	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS20195	ENOG4105BZU	Histidine kinase
FCL46_RS20210	ENOG4105CEY	Amp-dependent synthetase and ligase
FCL46_RS20215	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
FCL46_RS20230	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS20235	ENOG4105BZU	Histidine kinase
FCL46_RS20245	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
FCL46_RS20265	ENOG4105E5Q	amino acid AbC transporter
FCL46_RS20270	ENOG4105EAB	amino acid AbC transporter
FCL46_RS20275	ENOG4105EAD	ABC transporter
FCL46_RS20285	ENOG4105MRR	Transcriptional regulator (By similarity)
FCL46_RS20310	ENOG4105BZU	Histidine kinase
FCL46_RS20325	ENOG4108ISE	4Fe-4S ferredoxin, iron-sulfur binding
FCL46_RS20350	ENOG4107EJC	Preprotein translocase subunit SecG
FCL46_RS20355	ENOG4105CP7	Triose-phosphate isomerase
FCL46_RS20365	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
FCL46_RS20370	ENOG4105PW4	Sugar fermentation stimulation protein homolog
FCL46_RS20375	ENOG4105CD3	dihydroorotase
FCL46_RS20380	ENOG4105CXT	aspartate transcarbamylase
FCL46_RS20385	ENOG4105C3F	Signal peptidase i
FCL46_RS20415	ENOG4105GVR	general secretion pathway protein D
FCL46_RS20425	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
FCL46_RS20430	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
FCL46_RS20435	ENOG4105K4P	CoA-binding domain protein
FCL46_RS20440	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
FCL46_RS20470	ENOG4108RTU	Aldolase
FCL46_RS20475	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
FCL46_RS20480	ENOG4105CXK	mandelate racemase muconate lactonizing
FCL46_RS20490	ENOG4105GQU	Trap dicarboxylate transporter, dctp subunit
FCL46_RS20500	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL46_RS20505	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
FCL46_RS20510	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
FCL46_RS20520	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
FCL46_RS20525	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
FCL46_RS20530	ENOG4105CM2	brancheD-chain amino acid aminotransferase
FCL46_RS20535	ENOG4105F4G	Membrane
FCL46_RS20540	ENOG4105BZU	Histidine kinase
FCL46_RS20580	ENOG4105CNG	UPF0061 protein
FCL46_RS20590	ENOG4108YXU	transcriptional regulator AsnC family
FCL46_RS20605	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS20610	ENOG4105BZU	Histidine kinase
FCL46_RS20615	ENOG4105C0F	tryptophanase EC 4.1.99.1
FCL46_RS20645	ENOG4105DIN	metallophosphoesterase
FCL46_RS20655	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
FCL46_RS20665	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
FCL46_RS20710	ENOG4105VEQ	Cold shock protein
FCL46_RS20720	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
FCL46_RS20735	ENOG4108K0D	peptidase, M48
FCL46_RS20765	ENOG4105C6N	Formate acetyltransferase
FCL46_RS20775	ENOG4105HDD	phospholipase
FCL46_RS20780	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FCL46_RS20785	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
FCL46_RS20790	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
FCL46_RS20795	ENOG4105BZU	Histidine kinase
FCL46_RS20810	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
FCL46_RS20825	ENOG4105BZU	Histidine kinase
FCL46_RS20830	ENOG4107104	thymidine kinase
FCL46_RS20835	ENOG4105KG3	cytidine deaminase
FCL46_RS20840	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
FCL46_RS20855	ENOG4105IUR	peptidase C10
FCL46_RS20875	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
FCL46_RS20925	ENOG41079CX	
FCL46_RS20955	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
FCL46_RS20960	ENOG4107QXX	ABC transporter
FCL46_RS20965	ENOG4105EZ7	amino acid ABC transporter
FCL46_RS20970	ENOG4105DRP	amino acid AbC transporter
FCL46_RS20975	ENOG4105CDA	abc transporter atp-binding protein
FCL46_RS20985	ENOG41073TP	transcriptional regulator
FCL46_RS20990	ENOG4105CH5	extracellular solute-binding protein, family 7
FCL46_RS21000	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL46_RS21005	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
FCL46_RS21010	ENOG4107QR9	Iron-sulfur cluster binding protein
FCL46_RS21040	ENOG4105UIB	(ABC) transporter
FCL46_RS21045	ENOG4108JQ9	ABC transporter
FCL46_RS21050	ENOG4105DIH	basic membrane
FCL46_RS21060	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
FCL46_RS21070	ENOG4105C6N	Formate acetyltransferase
FCL46_RS21075	ENOG4105F87	Dehydratase
FCL46_RS21080	ENOG4105CNA	YD repeat protein
FCL46_RS21095	ENOG4105ENH	Sulfatase
FCL46_RS21145	ENOG4108DBC	nitroreductase
FCL46_RS21170	ENOG4105EFZ	amidohydrolase
FCL46_RS21230	ENOG41061ZR	Transcriptional regulator
FCL46_RS21265	ENOG4107RZC	phospholipase d
FCL46_RS21270	ENOG4105M0Y	
FCL46_RS21275	ENOG4107NA1	Endonuclease Exonuclease phosphatase
FCL46_RS21285	ENOG4105IPI	Membrane
FCL46_RS21300	ENOG4105J12	Multidrug resistance protein mdtN
FCL46_RS21320	ENOG4105BZU	Histidine kinase
FCL46_RS21350	ENOG4108WYP	Transcriptional regulator
FCL46_RS21355	ENOG4105F1A	Pyruvate formate-lyase
FCL46_RS21360	ENOG4105C6N	Formate acetyltransferase
FCL46_RS21370	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
FCL46_RS21375	ENOG4105S7S	phosphonate abc transporter
FCL46_RS21385	ENOG4105D5T	phosphonate abc transporter
FCL46_RS21415	ENOG4105DR4	Methyltransferase
FCL46_RS21440	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
FCL46_RS21445	ENOG4105BZN	citrate synthase
FCL46_RS21450	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS21455	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
FCL46_RS21460	ENOG4105EB3	Histidine kinase
FCL46_RS21520	ENOG4105DIH	basic membrane
FCL46_RS21525	ENOG4108JQ9	ABC transporter
FCL46_RS21530	ENOG41083U2	ABC transporter, permease
FCL46_RS21540	ENOG4105DZC	cytosine deaminase
FCL46_RS21550	ENOG4105EPH	radical SAM domain protein
FCL46_RS21555	ENOG41062JF	Transcriptional regulator
FCL46_RS21560	ENOG4105DDK	oxidoreductase, beta subunit
FCL46_RS21565	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
FCL46_RS21575	ENOG4105VN1	Heat shock protein
FCL46_RS21595	ENOG4105BZU	Histidine kinase
FCL46_RS21625	ENOG4105C9B	Cysteine desulfurase
FCL46_RS21630	ENOG4108IQE	Amp-dependent synthetase and ligase
FCL46_RS21655	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL46_RS21665	ENOG4105CH5	extracellular solute-binding protein, family 7
FCL46_RS21670	ENOG41073TP	transcriptional regulator
FCL46_RS21680	ENOG4105CD5	CoA-binding domain protein
FCL46_RS21685	ENOG4105CYC	Transferase
FCL46_RS21690	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
FCL46_RS21695	ENOG4107SEY	Conserved Protein
FCL46_RS21700	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FCL46_RS21705	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
FCL46_RS21720	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL46_RS21740	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
FCL46_RS21760	ENOG4105C8Q	Methyl-accepting chemotaxis
FCL46_RS21770	ENOG4105CQB	FAD linked oxidase domain protein
FCL46_RS21775	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
FCL46_RS21780	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
FCL46_RS21785	ENOG4107V1M	polysaccharide export protein
FCL46_RS21790	ENOG4105E12	capsule polysaccharide
FCL46_RS21795	ENOG41090SZ	ABC-2 type transporter
FCL46_RS21885	ENOG41084CK	capsule polysaccharide
FCL46_RS21890	ENOG41061N2	exported protein
FCL46_RS21895	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FCL46_RS21920	ENOG4105C2J	ABC transporter
FCL46_RS21925	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
FCL46_RS21935	ENOG4105EAD	ABC transporter
FCL46_RS21940	ENOG4106PMH	Extracellular solute-binding protein family 3
FCL46_RS21955	ENOG41082BV	acetyltransferase
FCL46_RS21960	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
FCL46_RS21965	ENOG4108R6G	acetyltransferase
FCL46_RS21975	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
FCL46_RS21980	ENOG4107QMS	site-determining protein
FCL46_RS21985	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
FCL46_RS21995	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FCL46_RS22030	ENOG4107YCY	Transcriptional regulator
FCL46_RS22040	ENOG4105HF0	Membrane
FCL46_RS22050	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
FCL46_RS22065	ENOG4105ERH	Fumarylacetoacetate hydrolase
FCL46_RS22080	ENOG4107QWE	)-transporter
FCL46_RS22090	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
FCL46_RS22095	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
FCL46_RS22120	ENOG410829K	Lysine exporter protein (Lyse ygga)
FCL46_RS22135	ENOG4108JQ7	(ABC) transporter
FCL46_RS22140	ENOG4105C3U	ABC transporter
FCL46_RS22145	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FCL46_RS22150	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
FCL46_RS22155	ENOG4105DEF	Extracellular solute-binding protein, family 5
FCL46_RS22160	ENOG4105C2W	permease
FCL46_RS22165	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
FCL46_RS22175	ENOG4105E98	transcriptional regulator DeoR family
FCL46_RS22185	ENOG4108IJ9	(ABC) transporter
FCL46_RS22200	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
FCL46_RS22215	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
FCL46_RS22220	ENOG4105DAA	L-lactate
FCL46_RS22225	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
FCL46_RS22250	ENOG4105QNF	Outer membrane lipoprotein
FCL46_RS22255	ENOG4108RAC	Rubrerythrin
FCL46_RS22260	ENOG4108ZXC	Two component transcriptional regulator, luxr family
FCL46_RS22265	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
FCL46_RS22270	ENOG4108JJA	ABC, transporter
FCL46_RS22280	ENOG4105BZU	Histidine kinase
FCL46_RS22290	ENOG4105DFG	type I secretion outer membrane protein
FCL46_RS22295	ENOG4105C72	UPF0176 protein
FCL46_RS22315	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
FCL46_RS22320	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FCL46_RS22340	ENOG4105H1G	trap transporter solute receptor taxi family
FCL46_RS22345	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
FCL46_RS22350	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
FCL46_RS22355	ENOG4105C8M	UPF0272 protein
FCL46_RS22360	ENOG4108ZAI	phosphatidylglycerophosphatase a
FCL46_RS22365	ENOG4107SVH	Potassium channel protein
FCL46_RS22395	ENOG4107SSZ	Phosphatase
FCL46_RS22440	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
FCL46_RS22485	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FCL46_RS22500	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
FCL46_RS22505	ENOG4105C4M	(Ubiquinol oxidase) subunit I
FCL46_RS22515	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
FCL46_RS22520	ENOG4108YZA	Nitrogen regulatory protein pii
FCL46_RS22530	ENOG4108JUA	Transcriptional regulator
FCL46_RS22535	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
FCL46_RS22540	ENOG4108YZA	Nitrogen regulatory protein pii
FCL46_RS22590	ENOG4105EX9	Membrane
FCL46_RS22630	ENOG4107XQ1	cobalamin (vitamin B12) biosynthesis CbiM protein
FCL46_RS22635	ENOG4108A51	
FCL46_RS22650	ENOG4108JJB	ABC transporter
FCL46_RS22670	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
FCL46_RS22675	ENOG4105CDV	Ompa motb domain protein
FCL46_RS22685	ENOG4105CYC	Transferase
FCL46_RS22690	ENOG4105C6K	Malic enzyme
FCL46_RS22700	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
FCL46_RS22715	ENOG4105E6M	Sulphatase-modifying factor protein
FCL46_RS22735	ENOG4105E6M	Sulphatase-modifying factor protein
FCL46_RS22750	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
FCL46_RS22755	ENOG4105ETX	regulatoR
FCL46_RS22760	ENOG4106F60	Histidine kinase
FCL46_RS22790	ENOG4105EFX	secretion protein, HlyD family
FCL46_RS22795	ENOG4105KK7	inner membrane protein YiaW
FCL46_RS22810	ENOG4105W39	Membrane
FCL46_RS22820	ENOG4105JNK	Glycosyl transferase (Group 1
FCL46_RS22830	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS22835	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
FCL46_RS22840	ENOG4107QR9	Iron-sulfur cluster binding protein
FCL46_RS22865	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
FCL46_RS22890	ENOG4105BZU	Histidine kinase
FCL46_RS22895	ENOG4107EFR	Flavocytochrome c
FCL46_RS22900	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FCL46_RS22920	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FCL46_RS22950	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FCL46_RS22960	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FCL46_RS22970	ENOG4105C2D	reductase
FCL46_RS23005	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FCL46_RS23045	ENOG4105BZU	Histidine kinase
FCL46_RS23065	ENOG4105C7W	Xanthine dehydrogenase
FCL46_RS23070	ENOG4105MJ6	selenium-dependent hydroxylase accessory protein YqeC
FCL46_RS23080	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
FCL46_RS23085	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
FCL46_RS23095	ENOG4108YZY	peptidylprolyl cis-trans isomerase
FCL46_RS23110	ENOG4105C3G	gtp-binding protein
FCL46_RS23135	ENOG4108ETH	Formylglycinamide ribotide synthetase
FCL46_RS23160	ENOG4105EHG	Permease protein
FCL46_RS23165	ENOG4105E0A	ABC, transporter
FCL46_RS23180	ENOG4108UXE	Protein tyrosine phosphatase
FCL46_RS23200	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
FCL46_RS23230	ENOG4105C7H	Helicase, RecD TraA family
FCL46_RS23260	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FCL46_RS23295	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
FCL46_RS23320	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
FCL46_RS23415	ENOG4105M6F	mutator MutT protein
FCL46_RS23440	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
FCL46_RS23465	ENOG4105CVR	type I restriction-modification system
FCL46_RS23470	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
FCL46_RS23475	ENOG4108I5C	dEAD DEAH box helicase
FCL46_RS23480	ENOG4105DXI	Major Facilitator superfamily
FCL46_RS23490	ENOG4105DXI	Major Facilitator superfamily
FCL46_RS23495	ENOG4105DY8	decarboxylase
FCL46_RS23505	ENOG4105K6H	D-cysteine desulfhydrase
FCL46_RS23515	ENOG4105DRR	Transcriptional regulator, GntR family
FCL46_RS23565	ENOG4107XWB	Zinc finger, swim domain protein
FCL46_RS23570	ENOG4105C0D	helicase
FCL46_RS23595	ENOG4105CBC	glutamate synthase
FCL46_RS23605	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
FCL46_RS23610	ENOG4105DZ0	fad dependent oxidoreductase
FCL46_RS23625	ENOG4105CEY	Amp-dependent synthetase and ligase
FCL46_RS23640	ENOG4105EMK	carboxylate amino acid amine transporter
FCL46_RS23655	ENOG4105WH1	Two component transcriptional regulator luxr family
FCL46_RS23770	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
FCL46_RS23775	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
FCL46_RS23785	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
FCL46_RS23790	ENOG4105EAB	amino acid AbC transporter
FCL46_RS23795	ENOG4105E5Q	amino acid AbC transporter
FCL46_RS23820	ENOG4105CHU	acetyl-coa acetyltransferase
FCL46_RS23830	ENOG4108JJB	ABC transporter
FCL46_RS23835	ENOG4108JJB	ABC transporter
FCL46_RS23850	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
FCL46_RS23865	ENOG4105C2J	ABC transporter
FCL46_RS23880	ENOG4108JQ7	(ABC) transporter
FCL46_RS23885	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FCL46_RS23890	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FCL46_RS23915	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
FCL46_RS23920	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
FCL46_RS23965	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
FCL46_RS23980	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
FCL46_RS23985	ENOG4105BZS	acriflavin resistance protein
FCL46_RS24020	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FCL46_RS24030	ENOG4105D49	3-dehydroquinate synthase
FCL46_RS24045	ENOG4107S9B	Shikimate dehydrogenase
FCL46_RS24050	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL46_RS24060	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
FCL46_RS24065	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
FCL46_RS24070	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
FCL46_RS24080	ENOG4105DQU	oxidoreductase, subunit beta
FCL46_RS24085	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
FCL46_RS24100	ENOG4108N2Y	auxin Efflux
FCL46_RS24105	ENOG4105C7K	acetolactate synthase
FCL46_RS24120	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
FCL46_RS24130	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
FCL46_RS24135	ENOG4107258	Transcriptional regulator
FCL46_RS24140	ENOG4105E4C	Lytic transglycosylase catalytic
FCL46_RS24145	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
FCL46_RS24155	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FCL46_RS24160	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
FCL46_RS24165	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FCL46_RS24170	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
FCL46_RS24180	ENOG4105CH7	arginosuccinase
FCL46_RS24185	ENOG4105CDH	Citrulline--aspartate ligase
FCL46_RS24190	ENOG4105DBV	ornithine carbamoyltransferase
FCL46_RS24195	ENOG4105C8Y	Acetylornithine aminotransferase
FCL46_RS24200	ENOG4105CAS	nag kinase
FCL46_RS24210	ENOG4108IUZ	ABC transporter
FCL46_RS24215	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FCL46_RS24240	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL46_RS24250	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
FCL46_RS24255	ENOG4105CND	Glycosyl transferase, family 2
FCL46_RS24270	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
FCL46_RS24275	ENOG4105F3H	Histidine kinase
FCL46_RS24285	ENOG4105DUM	transcriptional regulator, lysR family
FCL46_RS24305	ENOG4105C3R	Methionine synthase
FCL46_RS24330	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
FCL46_RS24340	ENOG4105BZ1	(ABC) transporter
FCL46_RS24350	ENOG4105MYT	Heat shock protein
FCL46_RS24360	ENOG4105D78	K07001 NTE family protein
FCL46_RS24380	ENOG4105D1F	ATP-binding protein
FCL46_RS24390	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
FCL46_RS24395	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
FCL46_RS24400	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
FCL46_RS24435	ENOG4105W3S	hemerythrin-like, metal-binding protein
FCL46_RS24455	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
FCL46_RS24475	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
FCL46_RS24480	ENOG4105C0H	protease
FCL46_RS24485	ENOG41063Z6	transcriptional regulator, lysR family
FCL46_RS24505	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
FCL46_RS24510	ENOG4105CRE	cytochrome C
FCL46_RS24520	ENOG4108R9S	DSBA oxidoreductase
FCL46_RS24530	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
FCL46_RS24545	ENOG4105CSA	Coproporphyrinogen iii oxidase
FCL46_RS24550	ENOG4105W5Q	DNA repair protein (RadC
FCL46_RS24555	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FCL46_RS24595	ENOG4108IYU	L-aspartate oxidase
FCL46_RS24600	ENOG4107QJE	Chromosome Partitioning Protein
FCL46_RS24605	ENOG4105FA0	parb-like partition protein
FCL46_RS24610	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
FCL46_RS24625	ENOG4108JUA	Transcriptional regulator
FCL46_RS24630	ENOG4105WPN	DNA integration recombination invertion protein
FCL46_RS24635	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
FCL46_RS24640	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
FCL46_RS24645	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FCL46_RS24650	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FCL46_RS24655	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
FCL46_RS24660	ENOG4107S1E	Beta-lactamase
FCL46_RS24680	ENOG4105VFE	sira family
FCL46_RS24685	ENOG4105CUC	YeeE YedE family protein
FCL46_RS24690	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FCL46_RS24695	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FCL46_RS24700	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
FCL46_RS24705	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FCL46_RS24710	ENOG4105CAT	Cytidine monophosphate kinase
FCL46_RS24715	ENOG4105KCK	Peptidoglycan-associated lipoprotein
FCL46_RS24725	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
FCL46_RS24740	ENOG4105BZU	Histidine kinase
FCL46_RS24745	ENOG4105E2T	synthase III
FCL46_RS24765	ENOG4105BZU	Histidine kinase
FCL46_RS24775	ENOG4108R96	Methyltransferase, YaeB family
FCL46_RS24790	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
FCL46_RS24795	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
FCL46_RS24800	ENOG4105E0X	reductase
FCL46_RS24820	ENOG4105CGZ	zinc metallopeptidase
FCL46_RS24840	ENOG4105D05	Receptor
FCL46_RS24860	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
FCL46_RS24870	ENOG4105E0X	reductase
FCL46_RS24875	ENOG4105EB3	Histidine kinase
FCL46_RS24880	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FCL46_RS24885	ENOG4105GVF	(ABC) transporter
FCL46_RS24900	ENOG4107QP3	malate synthase g
FCL46_RS24925	ENOG4107SWG	transcriptional regulator MERR family
FCL46_RS24965	ENOG4105E7U	AraC family transcriptional regulator
FCL46_RS24995	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FCL46_RS25005	ENOG4105C19	ABC transporter
FCL46_RS25025	ENOG4105C0A	alcohol dehydrogenase
FCL46_RS25030	ENOG4105KNY	Microcompartments protein
FCL46_RS25035	ENOG4105KNY	Microcompartments protein
FCL46_RS25040	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
FCL46_RS25060	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
FCL46_RS25070	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
FCL46_RS25075	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL46_RS25080	ENOG4105C6N	Formate acetyltransferase
FCL46_RS25085	ENOG4105F1A	Pyruvate formate-lyase
FCL46_RS25115	ENOG4105CNU	cell division protein FtsK
FCL46_RS25120	ENOG4105E9K	Isocitrate dehydrogenase
FCL46_RS25125	ENOG4105D58	Diguanylate phosphodiesterase
FCL46_RS25130	ENOG4105C5W	Aldolase
FCL46_RS25140	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FCL46_RS25155	ENOG4105D9Q	decarboxylase (Beta subunit)
FCL46_RS25160	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
FCL46_RS25175	ENOG4105CP2	von willebrand factor, type a
FCL46_RS25190	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
FCL46_RS25195	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
FCL46_RS25205	ENOG4105EMF	GntR family transcriptional regulator
FCL46_RS25220	ENOG4107YBY	Hydrolase
FCL46_RS25255	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
FCL46_RS25260	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
FCL46_RS25270	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
FCL46_RS25275	ENOG4107QR9	Iron-sulfur cluster binding protein
FCL46_RS25280	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
FCL46_RS25285	ENOG4108JUA	Transcriptional regulator
FCL46_RS25295	ENOG4107ZS6	Flavodoxin
FCL46_RS25335	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
FCL46_RS25360	ENOG4105F8J	Adenylate Guanylate cyclase
FCL46_RS25370	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
FCL46_RS25385	ENOG4105BZ1	(ABC) transporter
FCL46_RS25385	ENOG4105BZ1	(ABC) transporter
FCL46_RS25400	ENOG41083UI	stage II sporulation protein
FCL46_RS25420	ENOG4105BZU	Histidine kinase
FCL46_RS25430	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
FCL46_RS25435	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
FCL46_RS25450	ENOG4105EGD	dinuclear metal center protein, YbgI family
FCL46_RS25465	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
FCL46_RS25470	ENOG4107QHF	type ii secretion system protein e
FCL46_RS25475	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
FCL46_RS25500	ENOG4107S1Q	Phosphatase
FCL46_RS25515	ENOG4105BZU	Histidine kinase
FCL46_RS25525	ENOG4105E7U	AraC family transcriptional regulator
FCL46_RS25530	ENOG4108UPT	UPF0178 protein
FCL46_RS25550	ENOG4105C1A	potassium transporter peripheral membrane
FCL46_RS25560	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
FCL46_RS25565	ENOG4105EMY	transcriptional regulator
FCL46_RS25570	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
FCL46_RS25580	ENOG4105CJW	magnesium transporter
FCL46_RS25610	ENOG41081QV	Universal stress protein
FCL46_RS25640	ENOG4108IYU	L-aspartate oxidase
FCL46_RS25645	ENOG41082X2	rubredoxin
FCL46_RS25655	ENOG4105KTH	gatB Yqey
FCL46_RS25660	ENOG4105CQB	FAD linked oxidase domain protein
FCL46_RS25665	ENOG4107QSI	ABC, transporter
FCL46_RS25670	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
FCL46_RS25675	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FCL46_RS25680	ENOG4105C3U	ABC transporter
FCL46_RS25685	ENOG4108JQ7	(ABC) transporter
FCL46_RS25750	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FCL46_RS25765	ENOG4107RA9	decarboxylase
FCL46_RS25770	ENOG4107PPM	cobalt chelatase
FCL46_RS25785	ENOG4108NEV	two component transcriptional regulator, LytTR family
FCL46_RS25790	ENOG4108HRK	Histidine kinase
FCL46_RS25795	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL46_RS25805	ENOG4105CH5	extracellular solute-binding protein, family 7
FCL46_RS25810	ENOG4105C6K	Malic enzyme
FCL46_RS25815	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
FCL46_RS25840	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
FCL46_RS25870	ENOG4108MJI	response regulator
FCL46_RS25875	ENOG4105CGF	Aromatic amino acid aminotransferase
FCL46_RS25885	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
FCL46_RS25915	ENOG4105C6N	Formate acetyltransferase
FCL46_RS25920	ENOG4105F1A	Pyruvate formate-lyase
FCL46_RS25950	ENOG4105BZU	Histidine kinase
FCL46_RS25955	ENOG4105C0A	alcohol dehydrogenase
FCL46_RS25960	ENOG4105C7K	acetolactate synthase
FCL46_RS25965	ENOG4105M71	acetolactate synthase 1 regulatory subunit
FCL46_RS25970	ENOG4105VEQ	Cold shock protein
FCL46_RS25980	ENOG4105CY0	Metallo-Beta-Lactamase
FCL46_RS25985	ENOG4105CH5	extracellular solute-binding protein, family 7
FCL46_RS25995	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL46_RS26010	ENOG4107R0K	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
FCL46_RS26015	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
FCL46_RS26020	ENOG4105CHU	acetyl-coa acetyltransferase
FCL46_RS26045	ENOG4105CFP	Peptidase U32
FCL46_RS26055	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FCL46_RS26120	ENOG41081FY	multiple antibiotic resistance (MarC)-related
FCL46_RS26155	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
FCL46_RS26160	ENOG4105C4X	radical SAM domain protein
FCL46_RS26170	ENOG41090Y0	FMN-binding protein
FCL46_RS26175	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
FCL46_RS26180	ENOG4108JYZ	YitT family
FCL46_RS26195	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FCL46_RS26205	ENOG4107T9Q	phosphonate abc transporter
FCL46_RS26210	ENOG4105D5T	phosphonate abc transporter
FCL46_RS26215	ENOG4105S7S	phosphonate abc transporter
FCL46_RS26250	ENOG4108QV3	biosynthesis protein
FCL46_RS26260	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FCL46_RS26305	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
FCL46_RS26315	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
FCL46_RS26325	ENOG4107RA4	Glycosyl transferase (Group 1
FCL46_RS26330	ENOG4105CAQ	asparagine synthetase
FCL46_RS26335	ENOG4108PQP	glycosyl transferase group 1
FCL46_RS26340	ENOG4105CPC	Aldo Keto reductase
FCL46_RS26350	ENOG4105SHT	UspA domain-containing protein
FCL46_RS26365	ENOG4105E0Y	RtcB Protein
FCL46_RS26370	ENOG4105CYB	regulatoR
FCL46_RS26385	ENOG4105DY2	Paraquat-inducible protein b
FCL46_RS26390	ENOG4105F1S	paraquat-inducible protein a
FCL46_RS26400	ENOG4108UVJ	appr-1-p processing domain protein
FCL46_RS26410	ENOG4105BZU	Histidine kinase
FCL46_RS26415	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FCL46_RS26425	ENOG4108YXU	transcriptional regulator AsnC family
FCL46_RS26430	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
FCL46_RS26435	ENOG4107QSN	dihydrolipoamide acetyltransferase
FCL46_RS26440	ENOG4108UT2	hemolysin iii
FCL46_RS26445	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
FCL46_RS26455	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
FCL46_RS26465	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS26470	ENOG4105BZU	Histidine kinase
FCL46_RS26480	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
FCL46_RS26490	ENOG4108BGM	Quinol dehydrogenase periplasmic component
FCL46_RS26495	ENOG4105HEE	Binding Domain protein
FCL46_RS26500	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
FCL46_RS26505	ENOG4105WD1	Membrane
FCL46_RS26510	ENOG4105CEM	UPF0597 protein
FCL46_RS26515	ENOG4105KME	endoribonuclease L-psp
FCL46_RS26530	ENOG4105ED1	spovr family
FCL46_RS26540	ENOG4107PPM	cobalt chelatase
FCL46_RS26550	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
FCL46_RS26560	ENOG4108YBA	Histidine kinase
FCL46_RS26570	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
FCL46_RS26585	ENOG4105C0D	helicase
FCL46_RS26590	ENOG41067QW	Transcriptional regulator
FCL46_RS26600	ENOG4105CQB	FAD linked oxidase domain protein
FCL46_RS26605	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FCL46_RS26610	ENOG4108RA0	tripartite ATP-independent periplasmic transporter, DctQ component
FCL46_RS26615	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
FCL46_RS26630	ENOG4108USZ	hydrogenase
FCL46_RS26635	ENOG4105C45	hydrogenase expression formation protein (HypE)
FCL46_RS26640	ENOG4105CQS	hydrogenase expression formation protein HypD
FCL46_RS26660	ENOG4105DPX	Hydrogenase, large subunit
FCL46_RS26665	ENOG4105E3S	small subunit
FCL46_RS26670	ENOG4105DJ0	Poly(A) Polymerase
FCL46_RS26675	ENOG4105EA8	2-Nitropropane dioxygenase
FCL46_RS26680	ENOG4105CUT	histidyl-tRNA synthetase
FCL46_RS26685	ENOG4105C9M	aspartyl-trna synthetase
FCL46_RS26700	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
FCL46_RS26735	ENOG4105CQ7	ATP-dependent helicase
FCL46_RS26745	ENOG4108594	Permease of the drug metabolite transporter
FCL46_RS26750	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
FCL46_RS26755	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
FCL46_RS26760	ENOG4105D6A	Electron transport complex
FCL46_RS26765	ENOG41080WF	Electron transport complex, RnfABCDGE type, G subunit
FCL46_RS26770	ENOG4105DZB	Electron transport complex
FCL46_RS26775	ENOG4105DGN	Electron transport complex
FCL46_RS26780	ENOG4107SVV	electron transport complex, RnfABCDGE type, B subunit
FCL46_RS26805	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
FCL46_RS26820	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
FCL46_RS26840	ENOG4105CJ2	(LipO)protein
FCL46_RS26860	ENOG4108Q5Y	Membrane
FCL46_RS26865	ENOG4105DKW	ABC transporter
FCL46_RS26875	ENOG4105NAU	thioesterase Superfamily protein
FCL46_RS26885	ENOG4108IPJ	Membrane
FCL46_RS26890	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FCL46_RS26895	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
FCL46_RS26940	ENOG4107YCY	Transcriptional regulator
FCL46_RS26970	ENOG41084UG	Pfam:DUF1458
FCL46_RS26980	ENOG4105KVH	Transcriptional regulator
FCL46_RS26985	ENOG4105CS1	NAD(P)H quinone oxidoreductase
FCL46_RS27015	ENOG41081HM	2'-5' rna ligase
FCL46_RS27020	ENOG4105CUZ	uba thif-type nad fad binding protein
FCL46_RS27055	ENOG4107QM5	aconitate hydratase
FCL46_RS27060	ENOG4105ECY	inositol monophosphatase
FCL46_RS27065	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
FCL46_RS27070	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
FCL46_RS27075	ENOG4105E33	succinate dehydrogenase
FCL46_RS27105	ENOG4108IAB	Phoh family
FCL46_RS27110	ENOG4105DC7	peptidase M24
FCL46_RS27120	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
FCL46_RS27125	ENOG4107QXX	ABC transporter
FCL46_RS27145	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
FCL46_RS27175	ENOG4108UW5	maltose o-acetyltransferase
FCL46_RS27185	ENOG4105CAQ	asparagine synthetase
FCL46_RS27205	ENOG4105EXC	Acyl-transferase
FCL46_RS27225	ENOG4105CTS	PTS system mannitol-specific
FCL46_RS27230	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
FCL46_RS27235	ENOG4105CPQ	Dehydrogenase
FCL46_RS27240	ENOG4105DE4	1-phosphofructokinase
FCL46_RS27245	ENOG4105D2N	Aldolase
FCL46_RS27255	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
FCL46_RS27260	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
FCL46_RS27305	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS27315	ENOG4105BZU	Histidine kinase
FCL46_RS27325	ENOG4105BZU	Histidine kinase
FCL46_RS27335	ENOG4105EB3	Histidine kinase
FCL46_RS27345	ENOG4105E2K	Glycosyl transferase (Group 1
FCL46_RS27355	ENOG4105D78	K07001 NTE family protein
FCL46_RS27370	ENOG4105MYT	Heat shock protein
FCL46_RS27375	ENOG4105VN1	Heat shock protein
FCL46_RS27380	ENOG4108IV0	ABC, transporter
FCL46_RS27385	ENOG4105C0Z	ABC transporter
FCL46_RS27395	ENOG4105C32	Amino acid ABC transporter (Permease)
FCL46_RS27415	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
FCL46_RS27435	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
FCL46_RS27440	ENOG4105MSB	protein, conserved in bacteria
FCL46_RS27445	ENOG4108RAC	Rubrerythrin
FCL46_RS27470	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
FCL46_RS27485	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS27490	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCL46_RS27495	ENOG4105BZU	Histidine kinase
FCL46_RS27520	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
FCL46_RS27545	ENOG4105BZU	Histidine kinase
FCL46_RS27570	ENOG4105EB3	Histidine kinase
FCL46_RS27575	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
FCL46_RS27585	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
FCL46_RS27590	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
FCL46_RS27600	ENOG4107SVH	Potassium channel protein
FCL46_RS27605	ENOG4105VNH	ABC transporter solute-binding protein
FCL46_RS27610	ENOG4105CXZ	ABC transporter, permease
FCL46_RS27615	ENOG4108VGW	abc transporter atp-binding protein
FCL46_RS27620	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
FCL46_RS27650	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
FCL46_RS27655	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
FCL46_RS27660	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FCL46_RS27665	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FCL46_RS27670	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
FCL46_RS27675	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
FCL46_RS27710	ENOG4105D58	Diguanylate phosphodiesterase
FCL46_RS27745	ENOG4105DNZ	Alpha Beta Hydrolase
FCL46_RS27765	ENOG4108YXG	UPF0502 protein
FCL46_RS27770	ENOG4107RM6	sulfurtransferase
FCL46_RS27775	ENOG41073TP	transcriptional regulator
FCL46_RS27800	ENOG4107VXZ	Hydrolase
FCL46_RS27815	ENOG4105DEU	major facilitator superfamily
FCL46_RS27850	ENOG4105CIZ	coA-substrate-specific enzyme activase
FCL46_RS27885	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
FCL46_RS27890	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
FCL46_RS27895	ENOG4108JA2	transcriptioN-repair coupling factor
FCL46_RS27900	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FCL46_RS27905	ENOG4105MJ2	Competence protein