locus-tag	class	description
DSCA_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DSCA_RS00010	COG0277	FAD linked oxidase domain protein
DSCA_RS00020	COG0483	inositol monophosphate 1-phosphatase activity
DSCA_RS00030	COG0305	Participates in initiation and elongation during chromosome replication
DSCA_RS00035	COG0359	binds to the 23S rRNA
DSCA_RS00045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DSCA_RS00050	COG0360	Binds together with S18 to 16S ribosomal RNA
DSCA_RS00065	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DSCA_RS00075	COG0739	heme binding
DSCA_RS00095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DSCA_RS00105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DSCA_RS00120	COG1268	BioY protein
DSCA_RS00125	COG1122	ATPase activity
DSCA_RS00130	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DSCA_RS00135	COG3344	reverse transcriptase
DSCA_RS00140	COG0569	domain protein
DSCA_RS00170	COG1047	Peptidyl-prolyl cis-trans
DSCA_RS00185	COG2918	glutathione biosynthetic process
DSCA_RS00185	COG1181	Belongs to the D-alanine--D-alanine ligase family
DSCA_RS00190	COG0367	asparagine synthase
DSCA_RS00200	COG3100	YcgL domain-containing protein
DSCA_RS00200	COG0561	phosphatase activity
DSCA_RS00230	COG3437	response regulator, receiver
DSCA_RS00240	COG4585	Histidine kinase
DSCA_RS00280	COG3409	Peptidoglycan-binding domain 1 protein
DSCA_RS00280	COG3267	Type II secretory pathway component ExeA
DSCA_RS00290	COG4974	Belongs to the 'phage' integrase family
DSCA_RS00295	COG0582	viral genome integration into host DNA
DSCA_RS00300	COG4974	Belongs to the 'phage' integrase family
DSCA_RS00315	COG0569	domain protein
DSCA_RS00320	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DSCA_RS00325	COG1058	Belongs to the CinA family
DSCA_RS00325	COG1546	Belongs to the CinA family
DSCA_RS00340	COG1490	D-aminoacyl-tRNA deacylase activity
DSCA_RS00345	COG2183	response to ionizing radiation
DSCA_RS00350	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DSCA_RS00355	COG0758	DNA mediated transformation
DSCA_RS00360	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DSCA_RS00365	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DSCA_RS00370	COG1862	Preprotein translocase
DSCA_RS00375	COG1530	ribonuclease E activity
DSCA_RS00380	COG0495	leucyl-tRNA aminoacylation
DSCA_RS00390	COG0268	Binds directly to 16S ribosomal RNA
DSCA_RS00400	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DSCA_RS00415	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DSCA_RS00420	COG1573	uracil-dna glycosylase
DSCA_RS00440	COG4974	Belongs to the 'phage' integrase family
DSCA_RS00445	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DSCA_RS00450	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DSCA_RS00455	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DSCA_RS00460	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DSCA_RS00465	COG0137	argininosuccinate synthase activity
DSCA_RS00470	COG0165	Argininosuccinate lyase
DSCA_RS00480	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DSCA_RS00485	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DSCA_RS00495	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DSCA_RS00500	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DSCA_RS00540	COG0357	Ribosomal RNA small subunit methyltransferase G
DSCA_RS00545	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DSCA_RS00555	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DSCA_RS00560	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DSCA_RS00580	COG0559	Belongs to the binding-protein-dependent transport system permease family
DSCA_RS00600	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DSCA_RS00605	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DSCA_RS00610	COG0739	heme binding
DSCA_RS00615	COG0653	protein targeting
DSCA_RS00625	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DSCA_RS00630	COG0542	response to heat
DSCA_RS00635	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DSCA_RS00670	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DSCA_RS00675	COG0277	FAD linked oxidase domain protein
DSCA_RS00700	COG0776	regulation of translation
DSCA_RS00710	COG2204	response regulator
DSCA_RS00735	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DSCA_RS00755	COG3850	Histidine kinase
DSCA_RS00755	COG3437	response regulator, receiver
DSCA_RS00755	COG4999	Histidine kinase
DSCA_RS00755	COG2205	protein histidine kinase activity
DSCA_RS00770	COG1606	tRNA processing
DSCA_RS00780	COG4591	ABC-type transport system involved in lipoprotein release permease component
DSCA_RS00790	COG0791	NLP P60 protein
DSCA_RS00805	COG0116	Belongs to the methyltransferase superfamily
DSCA_RS00810	COG0488	(ABC) transporter
DSCA_RS00845	COG3064	Membrane
DSCA_RS00845	COG1073	alpha beta
DSCA_RS00845	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
DSCA_RS00880	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DSCA_RS00910	COG1881	PFAM PEBP family protein
DSCA_RS00940	COG0745	RESPONSE REGULATOR receiver
DSCA_RS00945	COG5002	protein histidine kinase activity
DSCA_RS00960	COG0626	cystathionine gamma-synthase activity
DSCA_RS00965	COG5598	trimethylamine methyltransferase
DSCA_RS00980	COG0494	nUDIX hydrolase
DSCA_RS00990	COG5002	protein histidine kinase activity
DSCA_RS00990	COG5001	Diguanylate cyclase
DSCA_RS00990	COG3447	MASE1 domain protein
DSCA_RS01000	COG0519	Catalyzes the synthesis of GMP from XMP
DSCA_RS01030	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DSCA_RS01050	COG3829	transcription factor binding
DSCA_RS01075	COG3409	Peptidoglycan-binding domain 1 protein
DSCA_RS01075	COG3267	Type II secretory pathway component ExeA
DSCA_RS01100	COG1204	response to ionizing radiation
DSCA_RS01105	COG2217	Heavy metal translocating P-type atpase
DSCA_RS01115	COG0515	serine threonine protein kinase
DSCA_RS01130	COG4191	Histidine kinase
DSCA_RS01150	COG2132	Multicopper oxidase
DSCA_RS01160	COG0556	nucleotide-excision repair
DSCA_RS01185	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DSCA_RS01270	COG1216	Glycosyl transferase, family 2
DSCA_RS01400	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DSCA_RS01425	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DSCA_RS01485	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DSCA_RS01525	COG1484	DNA-dependent DNA replication
DSCA_RS01530	COG4584	PFAM Integrase catalytic
DSCA_RS01570	COG1752	Esterase of the alpha-beta hydrolase superfamily
DSCA_RS01590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSCA_RS01605	COG1309	transcriptional regulator
DSCA_RS01870	COG0358	DNA primase activity
DSCA_RS01875	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DSCA_RS01925	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DSCA_RS01940	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DSCA_RS01950	COG2937	Belongs to the GPAT DAPAT family
DSCA_RS01975	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DSCA_RS01985	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DSCA_RS01985	COG3620	sequence-specific DNA binding
DSCA_RS01985	COG0617	tRNA 3'-terminal CCA addition
DSCA_RS01990	COG0731	radical SAM domain protein
DSCA_RS01990	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DSCA_RS01995	COG1459	type II secretion system
DSCA_RS02000	COG3852	Histidine kinase
DSCA_RS02010	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DSCA_RS02015	COG0673	inositol 2-dehydrogenase activity
DSCA_RS02020	COG3494	Protein of unknown function (DUF1009)
DSCA_RS02025	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DSCA_RS02030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DSCA_RS02035	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DSCA_RS02045	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DSCA_RS02050	COG1136	(ABC) transporter
DSCA_RS02055	COG4591	ABC-type transport system involved in lipoprotein release permease component
DSCA_RS02060	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DSCA_RS02065	COG1047	Peptidyl-prolyl cis-trans
DSCA_RS02070	COG0114	fumarate hydratase activity
DSCA_RS02085	COG2235	arginine
DSCA_RS02090	COG1254	Belongs to the acylphosphatase family
DSCA_RS02105	COG0438	transferase activity, transferring glycosyl groups
DSCA_RS02110	COG0366	Alpha amylase catalytic
DSCA_RS02115	COG0427	acetyl-CoA hydrolase
DSCA_RS02135	COG1228	amidohydrolase
DSCA_RS02140	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DSCA_RS02155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DSCA_RS02155	COG0426	domain, Protein
DSCA_RS02170	COG1028	Short-chain dehydrogenase reductase Sdr
DSCA_RS02175	COG1028	Short-chain dehydrogenase reductase Sdr
DSCA_RS02180	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DSCA_RS02220	COG3409	Peptidoglycan-binding domain 1 protein
DSCA_RS02220	COG3267	Type II secretory pathway component ExeA
DSCA_RS02255	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DSCA_RS02260	COG0149	triose-phosphate isomerase activity
DSCA_RS02275	COG1660	Displays ATPase and GTPase activities
DSCA_RS02280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSCA_RS02295	COG1137	ATPase activity
DSCA_RS02310	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DSCA_RS02315	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DSCA_RS02335	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DSCA_RS02340	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DSCA_RS02355	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DSCA_RS02360	COG2937	Belongs to the GPAT DAPAT family
DSCA_RS02375	COG3876	Protein conserved in bacteria
DSCA_RS02405	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DSCA_RS02410	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DSCA_RS02420	COG0616	signal peptide processing
DSCA_RS02425	COG1192	Involved in chromosome partitioning
DSCA_RS02435	COG0009	L-threonylcarbamoyladenylate synthase
DSCA_RS02440	COG0517	IMP dehydrogenase activity
DSCA_RS02440	COG0516	GMP reductase activity
DSCA_RS02445	COG0587	DNA-directed DNA polymerase activity
DSCA_RS02455	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DSCA_RS02465	COG0109	protoheme IX farnesyltransferase activity
DSCA_RS02480	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DSCA_RS02490	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DSCA_RS02495	COG1234	tRNA 3'-trailer cleavage
DSCA_RS02505	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DSCA_RS02505	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DSCA_RS02510	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DSCA_RS02530	COG0791	NLP P60 protein
DSCA_RS02530	COG1388	LysM domain
DSCA_RS02540	COG1342	Belongs to the UPF0251 family
DSCA_RS02545	COG0489	protein tyrosine kinase activity
DSCA_RS02560	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DSCA_RS02565	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DSCA_RS02570	COG1214	PFAM Peptidase M22, glycoprotease
DSCA_RS02575	COG0688	phosphatidylethanolamine metabolic process
DSCA_RS02580	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DSCA_RS02585	COG1758	RNA polymerase activity
DSCA_RS02590	COG0037	tRNA processing
DSCA_RS02595	COG1469	GTP cyclohydrolase I activity
DSCA_RS02605	COG4191	Histidine kinase
DSCA_RS02630	COG2204	response regulator
DSCA_RS02635	COG2204	response regulator
DSCA_RS02680	COG0456	acetyltransferase
DSCA_RS02820	COG0154	amidase activity
DSCA_RS02830	COG3920	Histidine kinase
DSCA_RS02840	COG3321	synthase
DSCA_RS02840	COG0604	alcohol dehydrogenase
DSCA_RS02840	COG1028	Short-chain dehydrogenase reductase Sdr
DSCA_RS02875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DSCA_RS02885	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DSCA_RS02900	COG2204	response regulator
DSCA_RS02905	COG5002	protein histidine kinase activity
DSCA_RS02925	COG0667	Aldo Keto reductase
DSCA_RS02930	COG0702	epimerase
DSCA_RS02965	COG2204	response regulator
DSCA_RS02980	COG0471	metal ion transport
DSCA_RS02985	COG2204	response regulator
DSCA_RS03005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DSCA_RS03005	COG0045	succinate-CoA ligase (ADP-forming) activity
DSCA_RS03005	COG1042	CoA-binding domain protein
DSCA_RS03015	COG0516	GMP reductase activity
DSCA_RS03015	COG0517	IMP dehydrogenase activity
DSCA_RS03035	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DSCA_RS03035	COG0446	pyridine nucleotide-disulphide oxidoreductase
DSCA_RS03050	COG0559	Belongs to the binding-protein-dependent transport system permease family
DSCA_RS03085	COG3344	reverse transcriptase
DSCA_RS03090	COG3260	NADH ubiquinone oxidoreductase 20
DSCA_RS03095	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSCA_RS03095	COG0649	NAD binding
DSCA_RS03100	COG0651	ATP synthesis coupled electron transport
DSCA_RS03110	COG0650	Formate hydrogenlyase subunit 4
DSCA_RS03115	COG0651	ATP synthesis coupled electron transport
DSCA_RS03140	COG0440	acetolactate synthase activity
DSCA_RS03165	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DSCA_RS03180	COG2089	acid synthase
DSCA_RS03190	COG1083	cytidylyl-transferase
DSCA_RS03220	COG0535	radical SAM domain protein
DSCA_RS03280	COG0438	transferase activity, transferring glycosyl groups
DSCA_RS03290	COG0438	transferase activity, transferring glycosyl groups
DSCA_RS03295	COG1215	transferase activity, transferring glycosyl groups
DSCA_RS03300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSCA_RS03355	COG0463	Glycosyl transferase, family 2
DSCA_RS03355	COG0457	Tetratricopeptide repeat
DSCA_RS03360	COG5442	Flagellar protein FlaF
DSCA_RS03365	COG5443	negative regulation of bacterial-type flagellum assembly
DSCA_RS03385	COG2204	response regulator
DSCA_RS03390	COG1815	bacterial-type flagellum-dependent cell motility
DSCA_RS03395	COG1558	bacterial-type flagellum-dependent cell motility
DSCA_RS03400	COG1677	Flagellar hook-basal body complex protein FliE
DSCA_RS03410	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DSCA_RS03420	COG1157	protein secretion by the type III secretion system
DSCA_RS03435	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DSCA_RS03465	COG1338	Plays a role in the flagellum-specific transport system
DSCA_RS03470	COG1987	bacterial-type flagellum assembly
DSCA_RS03475	COG1684	flagellar biosynthetic protein fliR
DSCA_RS03480	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DSCA_RS03485	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DSCA_RS03500	COG1191	sigma factor activity
DSCA_RS03510	COG4786	Flagellar basal body rod
DSCA_RS03525	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DSCA_RS03530	COG1706	bacterial-type flagellum-dependent cell motility
DSCA_RS03550	COG4786	Flagellar basal body rod
DSCA_RS03550	COG1256	bacterial-type flagellum assembly
DSCA_RS03560	COG1360	Flagellar Motor Protein
DSCA_RS03565	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DSCA_RS03575	COG0537	adenosine 5'-monophosphoramidase activity
DSCA_RS03580	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DSCA_RS03590	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DSCA_RS03590	COG0519	Catalyzes the synthesis of GMP from XMP
DSCA_RS03595	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
DSCA_RS03600	COG0135	phosphoribosylanthranilate isomerase activity
DSCA_RS03605	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DSCA_RS03615	COG4536	flavin adenine dinucleotide binding
DSCA_RS03620	COG1111	helicase
DSCA_RS03620	COG1205	dead DEAH box helicase
DSCA_RS03630	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DSCA_RS03635	COG0602	queuosine metabolic process
DSCA_RS03640	COG1482	cell wall glycoprotein biosynthetic process
DSCA_RS03660	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DSCA_RS03665	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DSCA_RS03695	COG3028	Belongs to the UPF0307 family
DSCA_RS03715	COG2257	FlhB HrpN YscU SpaS Family
DSCA_RS03725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DSCA_RS03735	COG0840	transmembrane signaling receptor activity
DSCA_RS03740	COG0179	Fumarylacetoacetate (FAA) hydrolase
DSCA_RS03745	COG3321	synthase
DSCA_RS03745	COG0604	alcohol dehydrogenase
DSCA_RS03745	COG3321	synthase
DSCA_RS03745	COG0604	alcohol dehydrogenase
DSCA_RS03755	COG2070	2-Nitropropane dioxygenase
DSCA_RS03755	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DSCA_RS03770	COG0006	proline dipeptidase activity
DSCA_RS03775	COG2050	protein possibly involved in aromatic compounds catabolism
DSCA_RS03775	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DSCA_RS03780	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
DSCA_RS03785	COG2414	aldehyde ferredoxin oxidoreductase
DSCA_RS03800	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DSCA_RS03840	COG4932	domain protein
DSCA_RS03840	COG1388	LysM domain
DSCA_RS03880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DSCA_RS03885	COG0745	RESPONSE REGULATOR receiver
DSCA_RS03910	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DSCA_RS03920	COG1217	gtp-binding protein TYPA
DSCA_RS03925	COG1250	3-hydroxyacyl-CoA dehydrogenase
DSCA_RS03935	COG0484	heat shock protein binding
DSCA_RS03940	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DSCA_RS03955	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DSCA_RS03960	COG2084	Dehydrogenase
DSCA_RS03970	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DSCA_RS04000	COG2264	protein methyltransferase activity
DSCA_RS04035	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DSCA_RS04040	COG1115	amino acid carrier protein
DSCA_RS04050	COG2414	aldehyde ferredoxin oxidoreductase
DSCA_RS04085	COG3409	Peptidoglycan-binding domain 1 protein
DSCA_RS04085	COG3267	Type II secretory pathway component ExeA
DSCA_RS04095	COG3344	reverse transcriptase
DSCA_RS04120	COG1401	restriction endodeoxyribonuclease activity
DSCA_RS04125	COG4268	DNA restriction-modification system
DSCA_RS04160	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DSCA_RS04180	COG3654	unkown
DSCA_RS04215	COG3034	peptidoglycan biosynthetic process
DSCA_RS04220	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
DSCA_RS04240	COG2197	response regulator
DSCA_RS04245	COG0745	RESPONSE REGULATOR receiver
DSCA_RS04260	COG0484	heat shock protein binding
DSCA_RS04280	COG0784	Response regulator, receiver
DSCA_RS04280	COG4191	Histidine kinase
DSCA_RS04305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSCA_RS04310	COG0318	PFAM AMP-dependent synthetase and ligase
DSCA_RS04315	COG0596	Alpha beta hydrolase
DSCA_RS04360	COG1399	metal-binding, possibly nucleic acid-binding protein
DSCA_RS04365	COG0450	alkyl hydroperoxide reductase
DSCA_RS04370	COG0737	Belongs to the 5'-nucleotidase family
DSCA_RS04385	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DSCA_RS04390	COG5002	protein histidine kinase activity
DSCA_RS04415	COG0166	Belongs to the GPI family
DSCA_RS04420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DSCA_RS04440	COG0438	transferase activity, transferring glycosyl groups
DSCA_RS04465	COG1215	transferase activity, transferring glycosyl groups
DSCA_RS04480	COG2814	Major facilitator Superfamily
DSCA_RS04485	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DSCA_RS04520	COG2165	general secretion pathway protein
DSCA_RS04530	COG1459	type II secretion system
DSCA_RS04535	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DSCA_RS04540	COG3409	Peptidoglycan-binding domain 1 protein
DSCA_RS04540	COG3267	Type II secretory pathway component ExeA
DSCA_RS04570	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DSCA_RS04575	COG0215	cysteine-tRNA ligase activity
DSCA_RS04580	COG0556	nucleotide-excision repair
DSCA_RS04585	COG0322	excinuclease ABC activity
DSCA_RS04590	COG0039	L-malate dehydrogenase activity
DSCA_RS04600	COG1100	Small GTP-binding protein
DSCA_RS04615	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DSCA_RS04625	COG1309	transcriptional regulator
DSCA_RS04630	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DSCA_RS04645	COG0745	RESPONSE REGULATOR receiver
DSCA_RS04650	COG5002	protein histidine kinase activity
DSCA_RS04650	COG2176	DNA-directed DNA polymerase activity
DSCA_RS04665	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DSCA_RS04670	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DSCA_RS04675	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DSCA_RS04685	COG1722	exodeoxyribonuclease VII activity
DSCA_RS04700	COG0670	Belongs to the BI1 family
DSCA_RS04705	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DSCA_RS04725	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DSCA_RS04730	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSCA_RS04735	COG0367	asparagine synthase
DSCA_RS04770	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DSCA_RS04795	COG0438	transferase activity, transferring glycosyl groups
DSCA_RS04825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSCA_RS04880	COG1215	transferase activity, transferring glycosyl groups
DSCA_RS04885	COG0297	glycogen (starch) synthase activity
DSCA_RS04885	COG0438	transferase activity, transferring glycosyl groups
DSCA_RS04895	COG1215	transferase activity, transferring glycosyl groups
DSCA_RS05015	COG4786	Flagellar basal body rod
DSCA_RS05025	COG0789	Transcriptional regulator
DSCA_RS05030	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS05035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSCA_RS05040	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DSCA_RS05065	COG4591	ABC-type transport system involved in lipoprotein release permease component
DSCA_RS05070	COG0577	efflux transmembrane transporter activity
DSCA_RS05070	COG1136	(ABC) transporter
DSCA_RS05095	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DSCA_RS05105	COG0494	nUDIX hydrolase
DSCA_RS05110	COG2204	response regulator
DSCA_RS05115	COG2204	response regulator
DSCA_RS05125	COG3437	response regulator, receiver
DSCA_RS05145	COG1253	flavin adenine dinucleotide binding
DSCA_RS05160	COG0438	transferase activity, transferring glycosyl groups
DSCA_RS05160	COG0297	glycogen (starch) synthase activity
DSCA_RS05170	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DSCA_RS05175	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DSCA_RS05175	COG0617	tRNA 3'-terminal CCA addition
DSCA_RS05175	COG3620	sequence-specific DNA binding
DSCA_RS05185	COG3830	Belongs to the UPF0237 family
DSCA_RS05190	COG2848	UPF0210 protein
DSCA_RS05200	COG1131	(ABC) transporter
DSCA_RS05205	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DSCA_RS05240	COG0776	regulation of translation
DSCA_RS05250	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DSCA_RS05255	COG1074	ATP-dependent DNA helicase activity
DSCA_RS05260	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DSCA_RS05285	COG1595	DNA-templated transcription, initiation
DSCA_RS05310	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DSCA_RS05325	COG0424	maF-like protein
DSCA_RS05330	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DSCA_RS05335	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DSCA_RS05345	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DSCA_RS05360	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DSCA_RS05365	COG1024	Enoyl-CoA hydratase
DSCA_RS05370	COG0860	N-Acetylmuramoyl-L-alanine amidase
DSCA_RS05370	COG1388	LysM domain
DSCA_RS05375	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DSCA_RS05390	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DSCA_RS05400	COG0489	protein tyrosine kinase activity
DSCA_RS05430	COG0745	RESPONSE REGULATOR receiver
DSCA_RS05435	COG1639	'signal transduction protein
DSCA_RS05455	COG0515	serine threonine protein kinase
DSCA_RS05455	COG2815	serine threonine protein kinase
DSCA_RS05460	COG0631	protein serine/threonine phosphatase activity
DSCA_RS05475	COG0726	polysaccharide deacetylase
DSCA_RS05665	COG0438	transferase activity, transferring glycosyl groups
DSCA_RS05685	COG2244	polysaccharide biosynthetic process
DSCA_RS05690	COG0463	Glycosyl transferase, family 2
DSCA_RS05720	COG0681	Belongs to the peptidase S26 family
DSCA_RS05725	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DSCA_RS05730	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
DSCA_RS05755	COG3267	Type II secretory pathway component ExeA
DSCA_RS05755	COG3409	Peptidoglycan-binding domain 1 protein
DSCA_RS05770	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DSCA_RS05775	COG0529	Catalyzes the synthesis of activated sulfate
DSCA_RS05775	COG2046	Belongs to the sulfate adenylyltransferase family
DSCA_RS05780	COG3209	COG3209 Rhs family protein
DSCA_RS05845	COG0367	asparagine synthase
DSCA_RS05870	COG4584	PFAM Integrase catalytic
DSCA_RS05885	COG4584	PFAM Integrase catalytic
DSCA_RS05890	COG1484	DNA-dependent DNA replication
DSCA_RS05925	COG0438	transferase activity, transferring glycosyl groups
DSCA_RS05930	COG1215	transferase activity, transferring glycosyl groups
DSCA_RS05940	COG0367	asparagine synthase
DSCA_RS05970	COG2244	polysaccharide biosynthetic process
DSCA_RS06030	COG0318	PFAM AMP-dependent synthetase and ligase
DSCA_RS06060	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DSCA_RS06090	COG1487	ribonuclease activity
DSCA_RS06105	COG2026	Addiction module toxin, RelE StbE family
DSCA_RS06115	COG0318	PFAM AMP-dependent synthetase and ligase
DSCA_RS06130	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DSCA_RS06175	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DSCA_RS06180	COG0489	protein tyrosine kinase activity
DSCA_RS06185	COG3944	biosynthesis protein
DSCA_RS06190	COG3604	Transcriptional regulator
DSCA_RS06210	COG2204	response regulator
DSCA_RS06225	COG2852	Protein conserved in bacteria
DSCA_RS06230	COG2271	Major facilitator Superfamily
DSCA_RS06235	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DSCA_RS06240	COG0482	sulfurtransferase activity
DSCA_RS06255	COG0501	Belongs to the peptidase M48B family
DSCA_RS06265	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DSCA_RS06290	COG0011	TIGRFAM Protein of
DSCA_RS06300	COG0644	oxidoreductase
DSCA_RS06320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DSCA_RS06330	COG2186	Transcriptional regulator
DSCA_RS06335	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DSCA_RS06340	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DSCA_RS06350	COG0540	Belongs to the ATCase OTCase family
DSCA_RS06355	COG1196	nuclear chromosome segregation
DSCA_RS06360	COG0552	protein localization to endoplasmic reticulum
DSCA_RS06370	COG2267	carboxylic ester hydrolase activity
DSCA_RS06375	COG0708	Exodeoxyribonuclease III
DSCA_RS06380	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DSCA_RS06385	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DSCA_RS06395	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DSCA_RS06400	COG1940	carbohydrate kinase activity
DSCA_RS06405	COG0587	DNA-directed DNA polymerase activity
DSCA_RS06425	COG2195	Cleaves the N-terminal amino acid of tripeptides
DSCA_RS06445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DSCA_RS06455	COG5002	protein histidine kinase activity
DSCA_RS06475	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DSCA_RS06510	COG0667	Aldo Keto reductase
DSCA_RS06535	COG2264	protein methyltransferase activity
DSCA_RS06545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DSCA_RS06555	COG0328	RNA-DNA hybrid ribonuclease activity
DSCA_RS06560	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DSCA_RS06590	COG1024	Enoyl-CoA hydratase
DSCA_RS06595	COG1028	Short-chain dehydrogenase reductase Sdr
DSCA_RS06630	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DSCA_RS06635	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DSCA_RS06660	COG0183	Belongs to the thiolase family
DSCA_RS06670	COG1837	Belongs to the UPF0109 family
DSCA_RS06675	COG2937	Belongs to the GPAT DAPAT family
DSCA_RS06695	COG0513	Belongs to the DEAD box helicase family
DSCA_RS06735	COG0196	riboflavin kinase activity
DSCA_RS06740	COG0242	peptide deformylase activity
DSCA_RS06745	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DSCA_RS06750	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DSCA_RS06750	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DSCA_RS06755	COG1459	type II secretion system
DSCA_RS06810	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DSCA_RS06815	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DSCA_RS06830	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DSCA_RS06835	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DSCA_RS06845	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DSCA_RS06850	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DSCA_RS06870	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DSCA_RS06885	COG0358	DNA primase activity
DSCA_RS06890	COG0131	Imidazoleglycerol-phosphate dehydratase
DSCA_RS06910	COG2217	Heavy metal translocating P-type atpase
DSCA_RS06915	COG1192	Involved in chromosome partitioning
DSCA_RS06925	COG1678	Uncharacterized ACR, COG1678
DSCA_RS06930	COG0129	dihydroxy-acid dehydratase activity
DSCA_RS06935	COG0028	Belongs to the TPP enzyme family
DSCA_RS06940	COG0440	acetolactate synthase activity
DSCA_RS06945	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DSCA_RS06950	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DSCA_RS06955	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DSCA_RS06975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSCA_RS07055	COG4968	Prepilin-type N-terminal cleavage methylation domain
DSCA_RS07060	COG1663	tetraacyldisaccharide 4'-kinase activity
DSCA_RS07065	COG1519	Transferase
DSCA_RS07085	COG0433	COG0433 Predicted ATPase
DSCA_RS07090	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
DSCA_RS07095	COG1253	flavin adenine dinucleotide binding
DSCA_RS07105	COG0006	proline dipeptidase activity
DSCA_RS07110	COG0747	negative chemotaxis
DSCA_RS07115	COG0601	transmembrane transport
DSCA_RS07120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DSCA_RS07125	COG0444	Belongs to the ABC transporter superfamily
DSCA_RS07130	COG4608	Belongs to the ABC transporter superfamily
DSCA_RS07170	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DSCA_RS07175	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DSCA_RS07185	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DSCA_RS07195	COG0101	tRNA pseudouridine synthase activity
DSCA_RS07200	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DSCA_RS07200	COG4651	solute:proton antiporter activity
DSCA_RS07210	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
DSCA_RS07250	COG0436	Aminotransferase
DSCA_RS07260	COG0668	transmembrane transport
DSCA_RS07280	COG0517	IMP dehydrogenase activity
DSCA_RS07280	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DSCA_RS07285	COG0205	6-phosphofructokinase activity
DSCA_RS07325	COG3956	TIGRFAM MazG family protein
DSCA_RS07335	COG1702	phosphate starvation-inducible protein PhoH
DSCA_RS07340	COG1480	7TM receptor with intracellular HD hydrolase
DSCA_RS07345	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DSCA_RS07350	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DSCA_RS07355	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DSCA_RS07355	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DSCA_RS07360	COG0802	atpase or kinase
DSCA_RS07365	COG0527	aspartate kinase activity
DSCA_RS07370	COG0284	orotidine-5'-phosphate decarboxylase activity
DSCA_RS07400	COG1051	belongs to the nudix hydrolase family
DSCA_RS07405	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS07410	COG2086	electron transfer activity
DSCA_RS07415	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DSCA_RS07420	COG1051	belongs to the nudix hydrolase family
DSCA_RS07430	COG3108	Peptidase M15
DSCA_RS07440	COG1278	Cold shock
DSCA_RS07455	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DSCA_RS07470	COG3119	arylsulfatase activity
DSCA_RS07495	COG1538	Outer membrane efflux protein
DSCA_RS07525	COG3040	lipid binding
DSCA_RS07550	COG1012	belongs to the aldehyde dehydrogenase family
DSCA_RS07555	COG2186	Transcriptional regulator
DSCA_RS07565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DSCA_RS07570	COG1120	ATPase activity
DSCA_RS07575	COG0811	peptide transport
DSCA_RS07580	COG0848	biopolymer transport protein
DSCA_RS07595	COG0803	Belongs to the bacterial solute-binding protein 9 family
DSCA_RS07600	COG1121	(ABC) transporter
DSCA_RS07605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DSCA_RS07605	COG1321	iron dependent repressor
DSCA_RS07610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DSCA_RS07615	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
DSCA_RS07620	COG1309	transcriptional regulator
DSCA_RS07625	COG2162	N-hydroxyarylamine O-acetyltransferase activity
DSCA_RS07660	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DSCA_RS07685	COG3008	intermembrane lipid transfer
DSCA_RS07690	COG2995	paraquat-inducible protein a
DSCA_RS07720	COG2204	response regulator
DSCA_RS07735	COG0489	protein tyrosine kinase activity
DSCA_RS07750	COG0731	radical SAM domain protein
DSCA_RS07750	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DSCA_RS07755	COG0655	NAD(P)H dehydrogenase (quinone) activity
DSCA_RS07760	COG3706	GGDEF domain
DSCA_RS07765	COG0840	transmembrane signaling receptor activity
DSCA_RS07775	COG0277	FAD linked oxidase domain protein
DSCA_RS07780	COG0456	acetyltransferase
DSCA_RS07800	COG2204	response regulator
DSCA_RS07835	COG1733	regulation of RNA biosynthetic process
DSCA_RS07850	COG2814	Major facilitator Superfamily
DSCA_RS07865	COG1538	Outer membrane efflux protein
DSCA_RS07870	COG0642	Histidine kinase
DSCA_RS07890	COG1518	maintenance of DNA repeat elements
DSCA_RS07945	COG1278	Cold shock
DSCA_RS07950	COG2067	long-chain fatty acid transport protein
DSCA_RS07970	COG3706	GGDEF domain
DSCA_RS07985	COG1022	Amp-dependent synthetase and ligase
DSCA_RS08015	COG0822	iron-sulfur transferase activity
DSCA_RS08035	COG1378	Sugar-specific transcriptional regulator TrmB
DSCA_RS08055	COG0683	leucine binding
DSCA_RS08080	COG0765	amino acid transport
DSCA_RS08090	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DSCA_RS08090	COG0519	Catalyzes the synthesis of GMP from XMP
DSCA_RS08095	COG0205	6-phosphofructokinase activity
DSCA_RS08105	COG0295	cytidine deaminase activity
DSCA_RS08135	COG0210	DNA helicase
DSCA_RS08155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DSCA_RS08165	COG2239	Acts as a magnesium transporter
DSCA_RS08170	COG1381	Involved in DNA repair and RecF pathway recombination
DSCA_RS08185	COG0752	glycyl-tRNA synthetase alpha subunit
DSCA_RS08190	COG0751	glycine-tRNA ligase activity
DSCA_RS08200	COG0813	purine-nucleoside phosphorylase activity
DSCA_RS08205	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DSCA_RS08210	COG0746	molybdenum cofactor guanylyltransferase activity
DSCA_RS08215	COG0406	alpha-ribazole phosphatase activity
DSCA_RS08220	COG1132	(ABC) transporter
DSCA_RS08225	COG1132	(ABC) transporter
DSCA_RS08230	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DSCA_RS08235	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DSCA_RS08235	COG1776	CheC inhibitor of MCP methylation
DSCA_RS08245	COG0589	response to stress
DSCA_RS08250	COG0237	dephospho-CoA kinase activity
DSCA_RS08255	COG2199	diguanylate cyclase activity
DSCA_RS08255	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DSCA_RS08260	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DSCA_RS08270	COG0778	Nitroreductase
DSCA_RS08285	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DSCA_RS08295	COG0105	UTP biosynthetic process
DSCA_RS08300	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
DSCA_RS08305	COG1119	ATPase activity
DSCA_RS08310	COG0473	3-isopropylmalate dehydrogenase activity
DSCA_RS08315	COG3409	Peptidoglycan-binding domain 1 protein
DSCA_RS08315	COG3267	Type II secretory pathway component ExeA
DSCA_RS08330	COG1918	ferrous iron import across plasma membrane
DSCA_RS08330	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DSCA_RS08340	COG0701	Predicted permease
DSCA_RS08345	COG0640	Transcriptional regulator
DSCA_RS08350	COG0235	Class ii aldolase
DSCA_RS08375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSCA_RS08375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DSCA_RS08380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DSCA_RS08385	COG5002	protein histidine kinase activity
DSCA_RS08430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSCA_RS08450	COG3681	Belongs to the UPF0597 family
DSCA_RS08470	COG2204	response regulator
DSCA_RS08560	COG1278	Cold shock
DSCA_RS08580	COG4191	Histidine kinase
DSCA_RS08590	COG2197	response regulator
DSCA_RS08635	COG1872	DUF167
DSCA_RS08640	COG0824	Thioesterase
DSCA_RS08680	COG0840	transmembrane signaling receptor activity
DSCA_RS08685	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
DSCA_RS08690	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DSCA_RS08695	COG2224	Isocitrate lyase
DSCA_RS08720	COG0559	Belongs to the binding-protein-dependent transport system permease family
DSCA_RS08740	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DSCA_RS08745	COG0123	including yeast histone deacetylase and acetoin utilization protein
DSCA_RS08755	COG0124	histidyl-tRNA synthetase
DSCA_RS08760	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DSCA_RS08765	COG1067	ATP-dependent peptidase activity
DSCA_RS08770	COG2204	response regulator
DSCA_RS08775	COG5002	protein histidine kinase activity
DSCA_RS08785	COG5012	cobalamin binding
DSCA_RS08795	COG0405	Gamma-glutamyltransferase
DSCA_RS08815	COG1177	transmembrane transport
DSCA_RS08825	COG3842	ATPase activity
DSCA_RS08835	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DSCA_RS08850	COG0628	permease
DSCA_RS08855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DSCA_RS08865	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DSCA_RS08870	COG2962	Rard protein
DSCA_RS08890	COG0525	valine-tRNA ligase activity
DSCA_RS08905	COG1032	radical SAM domain protein
DSCA_RS08910	COG1028	Short-chain dehydrogenase reductase Sdr
DSCA_RS08940	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DSCA_RS08945	COG1250	3-hydroxyacyl-CoA dehydrogenase
DSCA_RS08945	COG1024	Enoyl-CoA hydratase
DSCA_RS08950	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DSCA_RS08970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DSCA_RS08975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DSCA_RS08985	COG0251	oxidation-reduction process
DSCA_RS08990	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DSCA_RS09000	COG2205	protein histidine kinase activity
DSCA_RS09005	COG0745	RESPONSE REGULATOR receiver
DSCA_RS09020	COG0745	RESPONSE REGULATOR receiver
DSCA_RS09055	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DSCA_RS09060	COG0693	protein deglycase activity
DSCA_RS09070	COG0456	acetyltransferase
DSCA_RS09070	COG1214	PFAM Peptidase M22, glycoprotease
DSCA_RS09075	COG3706	GGDEF domain
DSCA_RS09080	COG0481	GTPase activity
DSCA_RS09085	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DSCA_RS09090	COG0066	3-isopropylmalate dehydratase activity
DSCA_RS09095	COG3273	potassium ion transport
DSCA_RS09095	COG0471	metal ion transport
DSCA_RS09105	COG4974	Belongs to the 'phage' integrase family
DSCA_RS09145	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DSCA_RS09160	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DSCA_RS09220	COG4822	anaerobic cobalamin biosynthetic process
DSCA_RS09225	COG1122	ATPase activity
DSCA_RS09230	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DSCA_RS09235	COG0310	cobalt ion transport
DSCA_RS09245	COG1408	metallophosphoesterase
DSCA_RS09255	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DSCA_RS09295	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DSCA_RS09300	COG0501	Belongs to the peptidase M48B family
DSCA_RS09325	COG0861	Integral membrane protein TerC family
DSCA_RS09355	COG0778	Nitroreductase
DSCA_RS09365	COG0517	IMP dehydrogenase activity
DSCA_RS09375	COG4974	Belongs to the 'phage' integrase family
DSCA_RS09455	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS09465	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS09470	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DSCA_RS09510	COG0840	transmembrane signaling receptor activity
DSCA_RS09520	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DSCA_RS09525	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DSCA_RS09575	COG0784	Response regulator, receiver
DSCA_RS09575	COG4191	Histidine kinase
DSCA_RS09590	COG0076	glutamate decarboxylase activity
DSCA_RS09625	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DSCA_RS09690	COG0318	PFAM AMP-dependent synthetase and ligase
DSCA_RS09695	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DSCA_RS09695	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DSCA_RS09710	COG0183	Belongs to the thiolase family
DSCA_RS09715	COG1250	3-hydroxyacyl-CoA dehydrogenase
DSCA_RS09715	COG1024	Enoyl-CoA hydratase
DSCA_RS09720	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DSCA_RS09720	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DSCA_RS09730	COG1024	Enoyl-CoA hydratase
DSCA_RS09735	COG1703	isobutyryl-CoA mutase activity
DSCA_RS09740	COG3604	Transcriptional regulator
DSCA_RS09745	COG0183	Belongs to the thiolase family
DSCA_RS09755	COG1250	3-hydroxyacyl-CoA dehydrogenase
DSCA_RS09760	COG2181	nitrate reductase activity
DSCA_RS09760	COG0247	lactate metabolic process
DSCA_RS09775	COG4656	Part of a membrane complex involved in electron transport
DSCA_RS09780	COG4658	electron transport chain
DSCA_RS09785	COG4659	FMN binding
DSCA_RS09790	COG4660	Part of a membrane complex involved in electron transport
DSCA_RS09795	COG4657	Part of a membrane complex involved in electron transport
DSCA_RS09800	COG2878	Part of a membrane complex involved in electron transport
DSCA_RS09805	COG0004	ammonium transporteR
DSCA_RS09835	COG0438	transferase activity, transferring glycosyl groups
DSCA_RS09840	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
DSCA_RS09865	COG0726	polysaccharide deacetylase
DSCA_RS09925	COG3267	Type II secretory pathway component ExeA
DSCA_RS09925	COG3409	Peptidoglycan-binding domain 1 protein
DSCA_RS09930	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DSCA_RS09960	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DSCA_RS10050	COG1639	'signal transduction protein
DSCA_RS10060	COG3409	Peptidoglycan-binding domain 1 protein
DSCA_RS10060	COG3267	Type II secretory pathway component ExeA
DSCA_RS10135	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DSCA_RS10145	COG0730	response to heat
DSCA_RS10155	COG3360	Dodecin
DSCA_RS10170	COG2204	response regulator
DSCA_RS10175	COG3852	Histidine kinase
DSCA_RS10185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DSCA_RS10190	COG1116	anion transmembrane transporter activity
DSCA_RS10230	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DSCA_RS10255	COG1309	transcriptional regulator
DSCA_RS10270	COG0028	Belongs to the TPP enzyme family
DSCA_RS10275	COG1028	Short-chain dehydrogenase reductase Sdr
DSCA_RS10285	COG0508	dehydrogenase complex catalyzes the overall conversion of
DSCA_RS10285	COG0596	Alpha beta hydrolase
DSCA_RS10300	COG0010	Belongs to the arginase family
DSCA_RS10310	COG0642	Histidine kinase
DSCA_RS10315	COG5002	protein histidine kinase activity
DSCA_RS10340	COG3706	GGDEF domain
DSCA_RS10345	COG0156	8-amino-7-oxononanoate synthase activity
DSCA_RS10360	COG2814	Major facilitator Superfamily
DSCA_RS10370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DSCA_RS10390	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DSCA_RS10390	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DSCA_RS10395	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DSCA_RS10405	COG0203	ribosomal protein L17
DSCA_RS10410	COG0202	RNA polymerase activity
DSCA_RS10415	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DSCA_RS10420	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DSCA_RS10425	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DSCA_RS10430	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DSCA_RS10435	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DSCA_RS10440	COG0201	protein transport
DSCA_RS10445	COG0200	Binds to the 23S rRNA
DSCA_RS10450	COG1841	ribosomal large subunit assembly
DSCA_RS10455	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DSCA_RS10460	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DSCA_RS10465	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DSCA_RS10470	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DSCA_RS10475	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DSCA_RS10480	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DSCA_RS10485	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DSCA_RS10490	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DSCA_RS10495	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DSCA_RS10500	COG0255	Belongs to the universal ribosomal protein uL29 family
DSCA_RS10505	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DSCA_RS10510	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DSCA_RS10515	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DSCA_RS10520	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DSCA_RS10525	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DSCA_RS10530	COG0089	rRNA binding
DSCA_RS10535	COG0088	Forms part of the polypeptide exit tunnel
DSCA_RS10540	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DSCA_RS10545	COG0051	transcription antitermination factor activity, RNA binding
DSCA_RS10550	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DSCA_RS10555	COG0049	tRNA binding
DSCA_RS10560	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DSCA_RS10565	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DSCA_RS10570	COG0085	RNA polymerase activity
DSCA_RS10575	COG0222	ribosome binding
DSCA_RS10580	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DSCA_RS10585	COG0081	regulation of translation
DSCA_RS10590	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DSCA_RS10595	COG0250	Participates in transcription elongation, termination and antitermination
DSCA_RS10600	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DSCA_RS10610	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DSCA_RS10615	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DSCA_RS10640	COG0741	lytic transglycosylase activity
DSCA_RS10640	COG1388	LysM domain
DSCA_RS10685	COG0686	Belongs to the AlaDH PNT family
DSCA_RS10740	COG2982	Protein involved in outer membrane biogenesis
DSCA_RS10745	COG0469	pyruvate kinase activity
DSCA_RS10750	COG2379	hydroxypyruvate reductase
DSCA_RS10770	COG1522	sequence-specific DNA binding
DSCA_RS10775	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DSCA_RS10780	COG1846	Transcriptional regulator
DSCA_RS10785	COG0346	lactoylglutathione lyase activity
DSCA_RS10790	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DSCA_RS10850	COG1575	Belongs to the MenA family. Type 1 subfamily
DSCA_RS10865	COG1121	(ABC) transporter
DSCA_RS10880	COG0501	Belongs to the peptidase M48B family
DSCA_RS10890	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DSCA_RS10895	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DSCA_RS10900	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DSCA_RS10905	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DSCA_RS10940	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DSCA_RS10975	COG0024	Methionine aminopeptidase
DSCA_RS10990	COG1950	PFAM Membrane protein of
DSCA_RS11005	COG2204	response regulator
DSCA_RS11080	COG2270	Major facilitator Superfamily
DSCA_RS11095	COG0318	PFAM AMP-dependent synthetase and ligase
DSCA_RS11100	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DSCA_RS11110	COG2204	response regulator
DSCA_RS11165	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DSCA_RS11165	COG0438	transferase activity, transferring glycosyl groups
DSCA_RS11210	COG0765	amino acid transport
DSCA_RS11215	COG0765	amino acid transport
DSCA_RS11220	COG1126	abc transporter atp-binding protein
DSCA_RS11225	COG2843	Capsule synthesis protein
DSCA_RS11230	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DSCA_RS11235	COG1181	Belongs to the D-alanine--D-alanine ligase family
DSCA_RS11290	COG0811	peptide transport
DSCA_RS11305	COG1047	Peptidyl-prolyl cis-trans
DSCA_RS11355	COG0737	Belongs to the 5'-nucleotidase family
DSCA_RS11380	COG3409	Peptidoglycan-binding domain 1 protein
DSCA_RS11380	COG3267	Type II secretory pathway component ExeA
DSCA_RS11425	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DSCA_RS11440	COG0438	transferase activity, transferring glycosyl groups
DSCA_RS11445	COG0438	transferase activity, transferring glycosyl groups
DSCA_RS11455	COG1216	Glycosyl transferase, family 2
DSCA_RS11460	COG1216	Glycosyl transferase, family 2
DSCA_RS11495	COG0529	Catalyzes the synthesis of activated sulfate
DSCA_RS11500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSCA_RS11545	COG0330	HflC and HflK could
DSCA_RS11560	COG1785	Belongs to the alkaline phosphatase family
DSCA_RS11565	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DSCA_RS11595	COG3153	acetyltransferase
DSCA_RS11640	COG1592	Rubrerythrin
DSCA_RS11640	COG1773	rubredoxin
DSCA_RS11655	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DSCA_RS11660	COG5002	protein histidine kinase activity
DSCA_RS11665	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DSCA_RS11670	COG0581	inorganic phosphate transmembrane transporter activity
DSCA_RS11675	COG0573	inorganic phosphate transmembrane transporter activity
DSCA_RS11680	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DSCA_RS11685	COG5002	protein histidine kinase activity
DSCA_RS11690	COG0745	RESPONSE REGULATOR receiver
DSCA_RS11700	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DSCA_RS11715	COG0573	inorganic phosphate transmembrane transporter activity
DSCA_RS11730	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DSCA_RS11745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DSCA_RS11760	COG1322	Protein conserved in bacteria
DSCA_RS11780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DSCA_RS11795	COG0745	RESPONSE REGULATOR receiver
DSCA_RS11800	COG5002	protein histidine kinase activity
DSCA_RS11810	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DSCA_RS11810	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DSCA_RS11820	COG1013	pyruvate-flavodoxin oxidoreductase activity
DSCA_RS11825	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DSCA_RS11825	COG0674	pyruvate-flavodoxin oxidoreductase activity
DSCA_RS11855	COG0277	FAD linked oxidase domain protein
DSCA_RS11860	COG2226	methyltransferase
DSCA_RS11895	COG1013	pyruvate-flavodoxin oxidoreductase activity
DSCA_RS11900	COG0674	pyruvate-flavodoxin oxidoreductase activity
DSCA_RS11900	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DSCA_RS11910	COG0588	phosphoglycerate mutase activity
DSCA_RS11925	COG2414	aldehyde ferredoxin oxidoreductase
DSCA_RS11940	COG0071	Belongs to the small heat shock protein (HSP20) family
DSCA_RS11960	COG0058	SHG alpha-glucan phosphorylase activity
DSCA_RS11965	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DSCA_RS11990	COG1309	transcriptional regulator
DSCA_RS12000	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DSCA_RS12020	COG0702	epimerase
DSCA_RS12055	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DSCA_RS12085	COG0604	alcohol dehydrogenase
DSCA_RS12125	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DSCA_RS12125	COG0574	Belongs to the PEP-utilizing enzyme family
DSCA_RS12130	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DSCA_RS12155	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DSCA_RS12160	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DSCA_RS12170	COG0501	Belongs to the peptidase M48B family
DSCA_RS12190	COG1122	ATPase activity
DSCA_RS12195	COG4120	Belongs to the binding-protein-dependent transport system permease family
DSCA_RS12210	COG0778	Nitroreductase
DSCA_RS12220	COG1785	Belongs to the alkaline phosphatase family
DSCA_RS12230	COG2414	aldehyde ferredoxin oxidoreductase
DSCA_RS12270	COG0318	PFAM AMP-dependent synthetase and ligase
DSCA_RS12275	COG0583	DNA-binding transcription factor activity
DSCA_RS12295	COG1720	tRNA m6t6A37 methyltransferase activity
DSCA_RS12310	COG1120	ATPase activity
DSCA_RS12315	COG4139	cobalamin transport
DSCA_RS12320	COG0427	acetyl-CoA hydrolase
DSCA_RS12330	COG0425	Belongs to the sulfur carrier protein TusA family
DSCA_RS12370	COG3209	COG3209 Rhs family protein
DSCA_RS12405	COG4974	Belongs to the 'phage' integrase family
DSCA_RS12410	COG4974	Belongs to the 'phage' integrase family
DSCA_RS12415	COG0358	DNA primase activity
DSCA_RS12500	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DSCA_RS12505	COG1176	ABC-type spermidine putrescine transport system, permease component I
DSCA_RS12520	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DSCA_RS12530	COG0573	inorganic phosphate transmembrane transporter activity
DSCA_RS12540	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
DSCA_RS12550	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
DSCA_RS12595	COG0840	transmembrane signaling receptor activity
DSCA_RS12605	COG0811	peptide transport
DSCA_RS12610	COG0848	biopolymer transport protein
DSCA_RS12640	COG0776	regulation of translation
DSCA_RS12650	COG1022	Amp-dependent synthetase and ligase
DSCA_RS12665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSCA_RS12700	COG1757	Na H antiporter
DSCA_RS12705	COG1522	sequence-specific DNA binding
DSCA_RS12710	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DSCA_RS12710	COG0515	serine threonine protein kinase
DSCA_RS12715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DSCA_RS12720	COG0765	amino acid transport
DSCA_RS12725	COG0765	amino acid transport
DSCA_RS12735	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DSCA_RS12740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DSCA_RS12750	COG1757	Na H antiporter
DSCA_RS12760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DSCA_RS12765	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DSCA_RS12775	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DSCA_RS12785	COG0840	transmembrane signaling receptor activity
DSCA_RS12800	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DSCA_RS12805	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DSCA_RS12855	COG0683	leucine binding
DSCA_RS12885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DSCA_RS12895	COG0747	negative chemotaxis
DSCA_RS12900	COG4608	Belongs to the ABC transporter superfamily
DSCA_RS12905	COG0444	Belongs to the ABC transporter superfamily
DSCA_RS12925	COG0277	FAD linked oxidase domain protein
DSCA_RS12935	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DSCA_RS12940	COG4895	conserved protein (DUF2196)
DSCA_RS12955	COG3012	SEC-C Motif Domain Protein
DSCA_RS12980	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DSCA_RS13025	COG2358	TRAP transporter, solute receptor (TAXI family
DSCA_RS13030	COG1216	Glycosyl transferase, family 2
DSCA_RS13065	COG3384	dioxygenase
DSCA_RS13100	COG1643	Atp-dependent helicase
DSCA_RS13125	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
DSCA_RS13140	COG0427	acetyl-CoA hydrolase
DSCA_RS13155	COG1151	hydroxylamine reductase activity
DSCA_RS13195	COG0437	4 iron, 4 sulfur cluster binding
DSCA_RS13210	COG0730	response to heat
DSCA_RS13225	COG3852	Histidine kinase
DSCA_RS13230	COG2204	response regulator
DSCA_RS13235	COG0071	Belongs to the small heat shock protein (HSP20) family
DSCA_RS13255	COG2096	Adenosyltransferase
DSCA_RS13270	COG0574	Belongs to the PEP-utilizing enzyme family
DSCA_RS13270	COG3848	Pyruvate phosphate dikinase
DSCA_RS13275	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DSCA_RS13285	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DSCA_RS13315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DSCA_RS13320	COG0352	thiamine-phosphate diphosphorylase activity
DSCA_RS13330	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DSCA_RS13335	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DSCA_RS13360	COG0596	Alpha beta hydrolase
DSCA_RS13375	COG2770	Histidine kinase
DSCA_RS13375	COG2208	phosphoserine phosphatase activity
DSCA_RS13400	COG0668	transmembrane transport
DSCA_RS13435	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DSCA_RS13440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DSCA_RS13460	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DSCA_RS13480	COG0557	exoribonuclease II activity
DSCA_RS13485	COG1309	transcriptional regulator
DSCA_RS13490	COG1811	Na channel or pump
DSCA_RS13515	COG0252	asparaginase activity
DSCA_RS13525	COG0456	acetyltransferase
DSCA_RS13535	COG1802	Transcriptional regulator
DSCA_RS13540	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DSCA_RS13545	COG1882	Formate acetyltransferase
DSCA_RS13560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DSCA_RS13600	COG1151	hydroxylamine reductase activity
DSCA_RS13605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DSCA_RS13615	COG1278	Cold shock
DSCA_RS13695	COG2951	lytic endotransglycosylase activity
DSCA_RS13700	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DSCA_RS13705	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DSCA_RS13710	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DSCA_RS13715	COG0217	transcriptional regulatory protein
DSCA_RS13720	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DSCA_RS13725	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DSCA_RS13750	COG3852	Histidine kinase
DSCA_RS13780	COG1522	sequence-specific DNA binding
DSCA_RS13785	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DSCA_RS13790	COG1333	cytochrome c biogenesis protein
DSCA_RS13810	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
DSCA_RS13825	COG1151	hydroxylamine reductase activity
DSCA_RS13865	COG2871	sodium ion transport
DSCA_RS13870	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
DSCA_RS13875	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
DSCA_RS13900	COG0372	Belongs to the citrate synthase family
DSCA_RS13905	COG1592	Rubrerythrin
DSCA_RS13905	COG1773	rubredoxin
DSCA_RS13910	COG0492	ferredoxin-NADP+ reductase activity
DSCA_RS13915	COG1607	acyl-coa hydrolase
DSCA_RS13950	COG0765	amino acid transport
DSCA_RS13955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DSCA_RS13960	COG0765	amino acid transport
DSCA_RS13975	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DSCA_RS13985	COG1172	Belongs to the binding-protein-dependent transport system permease family
DSCA_RS14065	COG1136	(ABC) transporter
DSCA_RS14075	COG0437	4 iron, 4 sulfur cluster binding
DSCA_RS14130	COG2217	Heavy metal translocating P-type atpase
DSCA_RS14135	COG0446	pyridine nucleotide-disulphide oxidoreductase
DSCA_RS14160	COG1028	Short-chain dehydrogenase reductase Sdr
DSCA_RS14180	COG1294	oxidase, subunit
DSCA_RS14185	COG1271	oxidase subunit
DSCA_RS14220	COG1671	Belongs to the UPF0178 family
DSCA_RS14225	COG0840	transmembrane signaling receptor activity
DSCA_RS14240	COG0745	RESPONSE REGULATOR receiver
DSCA_RS14245	COG2198	Histidine kinase
DSCA_RS14245	COG0643	Histidine kinase
DSCA_RS14250	COG0840	transmembrane signaling receptor activity
DSCA_RS14255	COG0835	chemotaxis
DSCA_RS14265	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DSCA_RS14270	COG2201	protein-glutamate methylesterase activity
DSCA_RS14295	COG0247	lactate metabolic process
DSCA_RS14350	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DSCA_RS14355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DSCA_RS14385	COG0076	glutamate decarboxylase activity
DSCA_RS14470	COG4717	serine-type aminopeptidase activity
DSCA_RS14475	COG0420	3'-5' exonuclease activity
DSCA_RS14490	COG0840	transmembrane signaling receptor activity
DSCA_RS14505	COG0840	transmembrane signaling receptor activity
DSCA_RS14510	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DSCA_RS14535	COG1024	Enoyl-CoA hydratase
DSCA_RS14550	COG2226	methyltransferase
DSCA_RS14575	COG3852	Histidine kinase
DSCA_RS14580	COG2855	membrane
DSCA_RS14600	COG2204	response regulator
DSCA_RS14625	COG0508	dehydrogenase complex catalyzes the overall conversion of
DSCA_RS14635	COG2267	carboxylic ester hydrolase activity
DSCA_RS14655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DSCA_RS14700	COG0735	belongs to the Fur family
DSCA_RS14715	COG0277	FAD linked oxidase domain protein
DSCA_RS14720	COG2721	sulfolactate sulfo-lyase activity
DSCA_RS14730	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DSCA_RS14740	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DSCA_RS14750	COG1013	pyruvate-flavodoxin oxidoreductase activity
DSCA_RS14755	COG0674	pyruvate-flavodoxin oxidoreductase activity
DSCA_RS14775	COG0443	Heat shock 70 kDa protein
DSCA_RS14795	COG1024	Enoyl-CoA hydratase
DSCA_RS14820	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DSCA_RS14950	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DSCA_RS14955	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DSCA_RS14960	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS14970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DSCA_RS14975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DSCA_RS14980	COG0698	ribose 5-phosphate isomerase
DSCA_RS14985	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DSCA_RS14990	COG2131	deaminase
DSCA_RS14995	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DSCA_RS15000	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DSCA_RS15000	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DSCA_RS15010	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DSCA_RS15010	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DSCA_RS15015	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DSCA_RS15020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DSCA_RS15025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSCA_RS15030	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DSCA_RS15035	COG0442	prolyl-tRNA aminoacylation
DSCA_RS15045	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DSCA_RS15050	COG1683	Conserved Protein
DSCA_RS15055	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DSCA_RS15060	COG3118	belongs to the thioredoxin family
DSCA_RS15065	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DSCA_RS15070	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DSCA_RS15080	COG0714	Associated with various cellular activities
DSCA_RS15110	COG0606	chelatase, subunit chli
DSCA_RS15115	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DSCA_RS15125	COG5000	phosphorelay sensor kinase activity
DSCA_RS15130	COG2204	response regulator
DSCA_RS15135	COG0742	ribosomal rna small subunit methyltransferase
DSCA_RS15140	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DSCA_RS15150	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DSCA_RS15155	COG0756	dUTP diphosphatase activity
DSCA_RS15160	COG0612	Peptidase, M16
DSCA_RS15165	COG1185	polyribonucleotide nucleotidyltransferase activity
DSCA_RS15170	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DSCA_RS15175	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DSCA_RS15180	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DSCA_RS15185	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DSCA_RS15195	COG3064	Membrane
DSCA_RS15195	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DSCA_RS15195	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DSCA_RS15195	COG3064	Membrane
DSCA_RS15200	COG0195	Participates in both transcription termination and antitermination
DSCA_RS15205	COG0779	Required for maturation of 30S ribosomal subunits
DSCA_RS15220	COG0072	phenylalanine-tRNA ligase activity
DSCA_RS15225	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DSCA_RS15230	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DSCA_RS15235	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DSCA_RS15240	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DSCA_RS15245	COG0590	tRNA wobble adenosine to inosine editing
DSCA_RS15255	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DSCA_RS15275	COG2983	Belongs to the UPF0260 family
DSCA_RS15295	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DSCA_RS15300	COG0741	lytic transglycosylase activity
DSCA_RS15310	COG0411	ABC transporter
DSCA_RS15330	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DSCA_RS15345	COG3344	reverse transcriptase
DSCA_RS15385	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DSCA_RS15390	COG2226	methyltransferase
DSCA_RS15400	COG0515	serine threonine protein kinase
DSCA_RS15400	COG2815	serine threonine protein kinase
DSCA_RS15435	COG1022	Amp-dependent synthetase and ligase
DSCA_RS15450	COG1615	UPF0182 protein
DSCA_RS15460	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DSCA_RS15460	COG2111	Na H antiporter
DSCA_RS15465	COG2111	Na H antiporter
DSCA_RS15470	COG1006	Multisubunit Na H antiporter MnhC subunit
DSCA_RS15475	COG0651	ATP synthesis coupled electron transport
DSCA_RS15480	COG1863	multisubunit Na H antiporter MnhE subunit
DSCA_RS15490	COG1320	monovalent cation:proton antiporter activity
DSCA_RS15495	COG2373	Large extracellular alpha-helical protein
DSCA_RS15500	COG4953	penicillin-binding protein 1C
DSCA_RS15515	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DSCA_RS15540	COG1245	4Fe-4S binding domain
DSCA_RS15540	COG2878	Part of a membrane complex involved in electron transport
DSCA_RS15560	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DSCA_RS15565	COG0402	S-adenosylhomocysteine deaminase activity
DSCA_RS15570	COG0402	S-adenosylhomocysteine deaminase activity
DSCA_RS15575	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DSCA_RS15595	COG1763	Mo-molybdopterin cofactor biosynthetic process
DSCA_RS15605	COG5002	protein histidine kinase activity
DSCA_RS15620	COG1595	DNA-templated transcription, initiation
DSCA_RS15630	COG5002	protein histidine kinase activity
DSCA_RS15635	COG4191	Histidine kinase
DSCA_RS15635	COG0784	Response regulator, receiver
DSCA_RS15650	COG1355	regulation of microtubule-based process
DSCA_RS15680	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DSCA_RS15690	COG1090	epimerase
DSCA_RS15695	COG3118	belongs to the thioredoxin family
DSCA_RS15700	COG0346	lactoylglutathione lyase activity
DSCA_RS15705	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DSCA_RS15740	COG1592	Rubrerythrin
DSCA_RS15745	COG2033	superoxide reductase activity
DSCA_RS15750	COG0426	domain, Protein
DSCA_RS15760	COG1271	oxidase subunit
DSCA_RS15765	COG1294	oxidase, subunit
DSCA_RS15780	COG1773	rubredoxin
DSCA_RS15790	COG0426	domain, Protein
DSCA_RS15820	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DSCA_RS15825	COG0154	amidase activity
DSCA_RS15830	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DSCA_RS15840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSCA_RS15890	COG0528	UMP kinase activity
DSCA_RS15910	COG3272	Protein of unknown function (DUF1722)
DSCA_RS15915	COG0300	oxidoreductase activity
DSCA_RS15920	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
DSCA_RS15955	COG0427	acetyl-CoA hydrolase
DSCA_RS15970	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DSCA_RS15970	COG0674	pyruvate-flavodoxin oxidoreductase activity
DSCA_RS15980	COG0446	pyridine nucleotide-disulphide oxidoreductase
DSCA_RS15990	COG0012	GTP binding
DSCA_RS15995	COG4822	anaerobic cobalamin biosynthetic process
DSCA_RS16015	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DSCA_RS16020	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DSCA_RS16025	COG0505	Belongs to the CarA family
DSCA_RS16030	COG0493	'glutamate synthase
DSCA_RS16045	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DSCA_RS16050	COG3850	Histidine kinase
DSCA_RS16050	COG3437	response regulator, receiver
DSCA_RS16050	COG2205	protein histidine kinase activity
DSCA_RS16050	COG4999	Histidine kinase
DSCA_RS16075	COG1959	2 iron, 2 sulfur cluster binding
DSCA_RS16085	COG0484	heat shock protein binding
DSCA_RS16090	COG3064	Membrane
DSCA_RS16090	COG0437	4 iron, 4 sulfur cluster binding
DSCA_RS16095	COG5557	Pfam Polysulphide reductase, NrfD
DSCA_RS16100	COG2181	nitrate reductase activity
DSCA_RS16105	COG0247	lactate metabolic process
DSCA_RS16115	COG0589	response to stress
DSCA_RS16125	COG2204	response regulator
DSCA_RS16135	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
DSCA_RS16140	COG3038	cytochrome b561
DSCA_RS16145	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DSCA_RS16145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DSCA_RS16175	COG5012	cobalamin binding
DSCA_RS16190	COG1737	Transcriptional regulator
DSCA_RS16195	COG0840	transmembrane signaling receptor activity
DSCA_RS16225	COG1007	ATP synthesis coupled electron transport
DSCA_RS16230	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSCA_RS16235	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DSCA_RS16240	COG0713	ATP synthesis coupled electron transport
DSCA_RS16250	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSCA_RS16255	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DSCA_RS16260	COG1034	ATP synthesis coupled electron transport
DSCA_RS16275	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSCA_RS16275	COG0649	NAD binding
DSCA_RS16275	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSCA_RS16280	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSCA_RS16300	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DSCA_RS16335	COG0492	ferredoxin-NADP+ reductase activity
DSCA_RS16340	COG0539	negative regulation of cytoplasmic translation
DSCA_RS16395	COG0784	Response regulator, receiver
DSCA_RS16395	COG2205	protein histidine kinase activity
DSCA_RS16420	COG0653	protein targeting
DSCA_RS16435	COG1595	DNA-templated transcription, initiation
DSCA_RS16460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DSCA_RS16475	COG0006	proline dipeptidase activity
DSCA_RS16480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DSCA_RS16485	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DSCA_RS16490	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DSCA_RS16490	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DSCA_RS16495	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DSCA_RS16500	COG1473	amidohydrolase
DSCA_RS16510	COG0006	proline dipeptidase activity
DSCA_RS16515	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DSCA_RS16525	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DSCA_RS16530	COG1414	Transcriptional regulator
DSCA_RS16535	COG1309	transcriptional regulator
DSCA_RS16540	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS16545	COG1703	isobutyryl-CoA mutase activity
DSCA_RS16545	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DSCA_RS16545	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DSCA_RS16555	COG1250	3-hydroxyacyl-CoA dehydrogenase
DSCA_RS16565	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS16580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DSCA_RS16650	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DSCA_RS16695	COG4191	Histidine kinase
DSCA_RS16700	COG2204	response regulator
DSCA_RS16705	COG2116	formate transmembrane transporter activity
DSCA_RS16715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSCA_RS16725	COG1538	Outer membrane efflux protein
DSCA_RS16735	COG1027	Aspartate ammonia-lyase
DSCA_RS16740	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DSCA_RS16750	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DSCA_RS16765	COG1309	transcriptional regulator
DSCA_RS16770	COG1902	pentaerythritol trinitrate reductase activity
DSCA_RS16780	COG1278	Cold shock
DSCA_RS16805	COG4977	sequence-specific DNA binding
DSCA_RS16820	COG0693	protein deglycase activity
DSCA_RS16835	COG1752	Esterase of the alpha-beta hydrolase superfamily
DSCA_RS16875	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DSCA_RS16885	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DSCA_RS16915	COG3852	Histidine kinase
DSCA_RS16920	COG2204	response regulator
DSCA_RS16925	COG0784	Response regulator, receiver
DSCA_RS16925	COG3437	response regulator, receiver
DSCA_RS16930	COG1280	lysine exporter protein (LysE YggA)
DSCA_RS16940	COG0564	pseudouridine synthase activity
DSCA_RS16950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DSCA_RS16960	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DSCA_RS16980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DSCA_RS16985	COG1522	sequence-specific DNA binding
DSCA_RS16990	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DSCA_RS17000	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DSCA_RS17005	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DSCA_RS17010	COG0321	lipoyl(octanoyl) transferase activity
DSCA_RS17020	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DSCA_RS17030	COG0741	lytic transglycosylase activity
DSCA_RS17040	COG4106	trans-aconitate 2-methyltransferase activity
DSCA_RS17045	COG0500	methyltransferase
DSCA_RS17055	COG0393	Putative heavy-metal-binding
DSCA_RS17075	COG0730	response to heat
DSCA_RS17080	COG2046	Belongs to the sulfate adenylyltransferase family
DSCA_RS17105	COG0142	geranyltranstransferase activity
DSCA_RS17110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DSCA_RS17115	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DSCA_RS17120	COG2086	electron transfer activity
DSCA_RS17125	COG1477	protein flavinylation
DSCA_RS17135	COG0409	Hydrogenase expression formation protein
DSCA_RS17140	COG3344	reverse transcriptase
DSCA_RS17145	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
DSCA_RS17150	COG0298	carbon dioxide binding
DSCA_RS17155	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
DSCA_RS17175	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
DSCA_RS17180	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
DSCA_RS17205	COG3108	Peptidase M15
DSCA_RS17210	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DSCA_RS17220	COG0154	amidase activity
DSCA_RS17225	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DSCA_RS17235	COG0018	arginyl-trna synthetase
DSCA_RS17245	COG1045	serine acetyltransferase
DSCA_RS17250	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DSCA_RS17295	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DSCA_RS17310	COG1605	Chorismate mutase
DSCA_RS17310	COG0077	Prephenate dehydratase
DSCA_RS17320	COG0436	Aminotransferase
DSCA_RS17325	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DSCA_RS17330	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DSCA_RS17335	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DSCA_RS17340	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DSCA_RS17345	COG0077	Prephenate dehydratase
DSCA_RS17345	COG1605	Chorismate mutase
DSCA_RS17350	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DSCA_RS17350	COG2111	Na H antiporter
DSCA_RS17355	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DSCA_RS17360	COG3260	NADH ubiquinone oxidoreductase 20
DSCA_RS17370	COG0649	NAD binding
DSCA_RS17400	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSCA_RS17410	COG0477	Major facilitator Superfamily
DSCA_RS17415	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DSCA_RS17425	COG3706	GGDEF domain
DSCA_RS17430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DSCA_RS17435	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DSCA_RS17460	COG1584	GPR1 FUN34 yaaH family protein
DSCA_RS17465	COG2204	response regulator
DSCA_RS17475	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DSCA_RS17480	COG0343	queuine tRNA-ribosyltransferase activity
DSCA_RS17485	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DSCA_RS17495	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DSCA_RS17495	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DSCA_RS17500	COG1703	isobutyryl-CoA mutase activity
DSCA_RS17505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DSCA_RS17520	COG0045	succinate-CoA ligase (ADP-forming) activity
DSCA_RS17525	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DSCA_RS17530	COG0375	protein maturation
DSCA_RS17535	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DSCA_RS17540	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DSCA_RS17625	COG1335	isochorismatase
DSCA_RS17645	COG0668	transmembrane transport
DSCA_RS17660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DSCA_RS17670	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DSCA_RS17670	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DSCA_RS17705	COG2267	carboxylic ester hydrolase activity
DSCA_RS17720	COG0765	amino acid transport
DSCA_RS17725	COG1126	abc transporter atp-binding protein
DSCA_RS17735	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
DSCA_RS17760	COG0477	Major facilitator Superfamily
DSCA_RS17775	COG0840	transmembrane signaling receptor activity
DSCA_RS17815	COG0277	FAD linked oxidase domain protein
DSCA_RS17830	COG0840	transmembrane signaling receptor activity
DSCA_RS17845	COG4191	Histidine kinase
DSCA_RS17850	COG3852	Histidine kinase
DSCA_RS17855	COG3852	Histidine kinase
DSCA_RS17875	COG2204	response regulator
DSCA_RS17885	COG3547	Transposase (IS116 IS110 IS902 family)
DSCA_RS17895	COG2197	response regulator
DSCA_RS17910	COG0559	Belongs to the binding-protein-dependent transport system permease family
DSCA_RS17930	COG1022	Amp-dependent synthetase and ligase
DSCA_RS17965	COG2030	dehydratase
DSCA_RS17970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DSCA_RS17985	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
DSCA_RS17990	COG0318	PFAM AMP-dependent synthetase and ligase
DSCA_RS18000	COG0511	ligase activity, forming carbon-carbon bonds
DSCA_RS18010	COG1024	Enoyl-CoA hydratase
DSCA_RS18015	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DSCA_RS18025	COG1309	transcriptional regulator
DSCA_RS18035	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DSCA_RS18045	COG1309	transcriptional regulator
DSCA_RS18055	COG3246	L-lysine catabolic process to acetate
DSCA_RS18070	COG0318	PFAM AMP-dependent synthetase and ligase
DSCA_RS18075	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS18100	COG0318	PFAM AMP-dependent synthetase and ligase
DSCA_RS18105	COG0318	PFAM AMP-dependent synthetase and ligase
DSCA_RS18110	COG0318	PFAM AMP-dependent synthetase and ligase
DSCA_RS18115	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DSCA_RS18135	COG0318	PFAM AMP-dependent synthetase and ligase
DSCA_RS18140	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS18145	COG0318	PFAM AMP-dependent synthetase and ligase
DSCA_RS18150	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS18175	COG0439	Biotin carboxylase
DSCA_RS18180	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DSCA_RS18195	COG1024	Enoyl-CoA hydratase
DSCA_RS18200	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS18205	COG0318	PFAM AMP-dependent synthetase and ligase
DSCA_RS18210	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS18225	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS18230	COG0318	PFAM AMP-dependent synthetase and ligase
DSCA_RS18255	COG0439	Biotin carboxylase
DSCA_RS18260	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DSCA_RS18275	COG2204	response regulator
DSCA_RS18295	COG0318	PFAM AMP-dependent synthetase and ligase
DSCA_RS18300	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS18315	COG1028	Short-chain dehydrogenase reductase Sdr
DSCA_RS18320	COG2030	dehydratase
DSCA_RS18325	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS18360	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS18365	COG0318	PFAM AMP-dependent synthetase and ligase
DSCA_RS18370	COG1024	Enoyl-CoA hydratase
DSCA_RS18385	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS18390	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DSCA_RS18400	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS18405	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS18410	COG1021	2,3-dihydroxybenzoate-AMP ligase
DSCA_RS18435	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS18445	COG0318	PFAM AMP-dependent synthetase and ligase
DSCA_RS18450	COG0183	Belongs to the thiolase family
DSCA_RS18455	COG1028	Short-chain dehydrogenase reductase Sdr
DSCA_RS18460	COG1028	Short-chain dehydrogenase reductase Sdr
DSCA_RS18480	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS18500	COG1024	Enoyl-CoA hydratase
DSCA_RS18515	COG3829	transcription factor binding
DSCA_RS18515	COG3290	protein histidine kinase activity
DSCA_RS18520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DSCA_RS18525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DSCA_RS18555	COG0840	transmembrane signaling receptor activity
DSCA_RS18575	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS18580	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DSCA_RS18585	COG1250	3-hydroxyacyl-CoA dehydrogenase
DSCA_RS18590	COG1846	Transcriptional regulator
DSCA_RS18600	COG1028	Short-chain dehydrogenase reductase Sdr
DSCA_RS18605	COG1042	CoA-binding domain protein
DSCA_RS18605	COG0045	succinate-CoA ligase (ADP-forming) activity
DSCA_RS18605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DSCA_RS18620	COG0183	Belongs to the thiolase family
DSCA_RS18625	COG1024	Enoyl-CoA hydratase
DSCA_RS18630	COG1250	3-hydroxyacyl-CoA dehydrogenase
DSCA_RS18655	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
DSCA_RS18660	COG1802	Transcriptional regulator
DSCA_RS18690	COG0745	RESPONSE REGULATOR receiver
DSCA_RS18700	COG2181	nitrate reductase activity
DSCA_RS18730	COG0564	pseudouridine synthase activity
DSCA_RS18745	COG3243	poly(R)-hydroxyalkanoic acid synthase
DSCA_RS18780	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
DSCA_RS18790	COG2030	dehydratase
DSCA_RS18825	COG3344	reverse transcriptase
DSCA_RS18860	COG1402	creatininase
DSCA_RS18870	COG0714	Associated with various cellular activities
DSCA_RS18890	COG2304	oxidoreductase activity
DSCA_RS18915	COG1121	(ABC) transporter
DSCA_RS18920	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DSCA_RS18930	COG0701	Predicted permease
DSCA_RS18945	COG2207	Transcriptional regulator
DSCA_RS18950	COG1979	alcohol dehydrogenase
DSCA_RS18965	COG1178	ABC-type Fe3 transport system permease component
DSCA_RS18990	COG1104	cysteine desulfurase activity
DSCA_RS19010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DSCA_RS19010	COG0357	Ribosomal RNA small subunit methyltransferase G
DSCA_RS19020	COG1233	COG1233 Phytoene dehydrogenase and related
DSCA_RS19025	COG1233	COG1233 Phytoene dehydrogenase and related
DSCA_RS19045	COG1028	Short-chain dehydrogenase reductase Sdr
DSCA_RS19095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DSCA_RS19105	COG0542	response to heat
DSCA_RS19115	COG2204	response regulator
DSCA_RS19125	COG0123	including yeast histone deacetylase and acetoin utilization protein
DSCA_RS19130	COG4191	Histidine kinase
DSCA_RS19135	COG2204	response regulator
DSCA_RS19150	COG2204	response regulator
DSCA_RS19170	COG0861	Integral membrane protein TerC family
DSCA_RS19180	COG1794	racemase activity, acting on amino acids and derivatives
DSCA_RS19185	COG0631	protein serine/threonine phosphatase activity
DSCA_RS19205	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DSCA_RS19230	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DSCA_RS19235	COG0356	it plays a direct role in the translocation of protons across the membrane
DSCA_RS19250	COG1234	tRNA 3'-trailer cleavage
DSCA_RS19255	COG1648	precorrin-2 dehydrogenase activity
DSCA_RS19255	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DSCA_RS19260	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DSCA_RS19265	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DSCA_RS19270	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DSCA_RS19280	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DSCA_RS19285	COG0613	PHP domain protein
DSCA_RS19290	COG0571	ribonuclease III activity
DSCA_RS19305	COG2358	TRAP transporter, solute receptor (TAXI family
DSCA_RS19325	COG0076	glutamate decarboxylase activity
DSCA_RS19340	COG1042	CoA-binding domain protein
DSCA_RS19340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DSCA_RS19340	COG0045	succinate-CoA ligase (ADP-forming) activity
DSCA_RS19345	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DSCA_RS19350	COG1027	Aspartate ammonia-lyase
DSCA_RS19375	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DSCA_RS19390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DSCA_RS19430	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DSCA_RS19435	COG1918	ferrous iron import across plasma membrane
DSCA_RS19475	COG1937	Protein conserved in bacteria
DSCA_RS19500	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DSCA_RS19520	COG3383	formate dehydrogenase (NAD+) activity
DSCA_RS19535	COG0446	pyridine nucleotide-disulphide oxidoreductase
DSCA_RS19535	COG1902	pentaerythritol trinitrate reductase activity
DSCA_RS19540	COG0402	S-adenosylhomocysteine deaminase activity
DSCA_RS19545	COG1079	Belongs to the binding-protein-dependent transport system permease family
DSCA_RS19550	COG4603	Belongs to the binding-protein-dependent transport system permease family
DSCA_RS19555	COG3845	ABC transporter
DSCA_RS19595	COG3093	addiction module antidote protein HigA
DSCA_RS19615	COG1061	Type III restriction enzyme res subunit
DSCA_RS19650	COG1196	nuclear chromosome segregation
DSCA_RS19650	COG3264	Mechanosensitive ion channel
DSCA_RS19660	COG0070	glutamate synthase
DSCA_RS19660	COG0067	glutamate synthase
DSCA_RS19660	COG0069	glutamate synthase activity
DSCA_RS19675	COG0004	ammonium transporteR
DSCA_RS19685	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DSCA_RS19690	COG0069	glutamate synthase activity
DSCA_RS19715	COG3848	Pyruvate phosphate dikinase
DSCA_RS19715	COG0574	Belongs to the PEP-utilizing enzyme family
DSCA_RS19730	COG0308	aminopeptidase N
DSCA_RS19740	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DSCA_RS19785	COG1177	transmembrane transport
DSCA_RS19790	COG1176	ABC-type spermidine putrescine transport system, permease component I
DSCA_RS19795	COG3842	ATPase activity
DSCA_RS19800	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DSCA_RS19810	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DSCA_RS19830	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DSCA_RS19840	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DSCA_RS19850	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
DSCA_RS19865	COG2223	nitrite transmembrane transporter activity
DSCA_RS19885	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DSCA_RS19905	COG0116	Belongs to the methyltransferase superfamily
DSCA_RS19910	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
DSCA_RS19925	COG0629	single-stranded DNA binding
DSCA_RS19930	COG1151	hydroxylamine reductase activity
DSCA_RS19945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DSCA_RS19955	COG1028	Short-chain dehydrogenase reductase Sdr
DSCA_RS19980	COG1024	Enoyl-CoA hydratase
DSCA_RS19985	COG0584	glycerophosphoryl diester phosphodiesterase
DSCA_RS20005	COG1175	transmembrane transport
DSCA_RS20010	COG1653	transport
DSCA_RS20015	COG3842	ATPase activity
DSCA_RS20020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DSCA_RS20025	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DSCA_RS20030	COG3118	belongs to the thioredoxin family
DSCA_RS20045	COG1342	Belongs to the UPF0251 family
DSCA_RS20095	COG0653	protein targeting
DSCA_RS20125	COG2204	response regulator
DSCA_RS20140	COG0446	pyridine nucleotide-disulphide oxidoreductase
DSCA_RS20155	COG3118	belongs to the thioredoxin family
DSCA_RS20165	COG0395	ABC-type sugar transport system, permease component
DSCA_RS20170	COG1175	transmembrane transport
DSCA_RS20180	COG3842	ATPase activity
DSCA_RS20185	COG1349	DNA-binding transcription factor activity
DSCA_RS20190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSCA_RS20190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DSCA_RS20200	COG5557	Pfam Polysulphide reductase, NrfD
DSCA_RS20205	COG0437	4 iron, 4 sulfur cluster binding
DSCA_RS20205	COG3064	Membrane
DSCA_RS20220	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DSCA_RS20225	COG0745	RESPONSE REGULATOR receiver
DSCA_RS20230	COG0646	methionine synthase
DSCA_RS20230	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DSCA_RS20245	COG0493	'glutamate synthase
DSCA_RS20255	COG2204	response regulator
DSCA_RS20270	COG3845	ABC transporter
DSCA_RS20285	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
DSCA_RS20310	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DSCA_RS20315	COG1847	R3H domain protein
DSCA_RS20320	COG0706	membrane insertase activity
DSCA_RS20325	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DSCA_RS20330	COG0594	ribonuclease P activity
DSCA_RS20335	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DSCA_RS20350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DSCA_RS20355	COG0017	Asparaginyl-tRNA synthetase
DSCA_RS20360	COG0187	DNA topoisomerase II activity
DSCA_RS20365	COG0592	DNA-directed DNA polymerase activity
DSCA_RS20380	COG0210	DNA helicase
DSCA_RS20395	COG2197	response regulator
DSCA_RS20410	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DSCA_RS20415	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DSCA_RS20420	COG0436	Aminotransferase
DSCA_RS20450	COG5002	protein histidine kinase activity
DSCA_RS20465	COG1694	Mazg nucleotide pyrophosphohydrolase
DSCA_RS20470	COG0521	Mo-molybdopterin cofactor biosynthetic process
DSCA_RS20475	COG0746	molybdenum cofactor guanylyltransferase activity
DSCA_RS20485	COG0315	cyclic pyranopterin monophosphate synthase activity
DSCA_RS20490	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
DSCA_RS20495	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DSCA_RS20500	COG0805	protein transport
DSCA_RS20515	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DSCA_RS20530	COG1797	cobyrinic acid a,c-diamide synthase activity
DSCA_RS20540	COG2221	Nitrite and sulphite reductase 4Fe-4S
DSCA_RS20545	COG2221	Nitrite and sulphite reductase 4Fe-4S
DSCA_RS20560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DSCA_RS20580	COG0395	ABC-type sugar transport system, permease component
DSCA_RS20585	COG1175	transmembrane transport
DSCA_RS20595	COG3842	ATPase activity
DSCA_RS20600	COG1349	DNA-binding transcription factor activity
DSCA_RS20605	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DSCA_RS20610	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
DSCA_RS20635	COG0484	heat shock protein binding
DSCA_RS20640	COG0720	synthase
DSCA_RS20645	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DSCA_RS20655	COG2884	Cell division ATP-binding protein ftsE
DSCA_RS20660	COG2177	Part of the ABC transporter FtsEX involved in
DSCA_RS20670	COG0793	Belongs to the peptidase S41A family
DSCA_RS20700	COG2264	protein methyltransferase activity
DSCA_RS20720	COG0310	cobalt ion transport
DSCA_RS20730	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DSCA_RS20735	COG1122	ATPase activity
DSCA_RS20760	COG1802	Transcriptional regulator
DSCA_RS20770	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DSCA_RS20775	COG1127	ABC transporter
DSCA_RS20780	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DSCA_RS20790	COG2853	Lipoprotein
DSCA_RS20800	COG3267	Type II secretory pathway component ExeA
DSCA_RS20800	COG3409	Peptidoglycan-binding domain 1 protein
DSCA_RS20810	COG0739	heme binding
DSCA_RS20845	COG4822	anaerobic cobalamin biosynthetic process
DSCA_RS20885	COG1793	dna ligase
DSCA_RS20955	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DSCA_RS20955	COG0475	glutathione-regulated potassium exporter activity
DSCA_RS20960	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DSCA_RS20975	COG0598	Magnesium transport protein CorA
DSCA_RS20985	COG4948	Mandelate Racemase Muconate Lactonizing
DSCA_RS21000	COG0133	tryptophan synthase activity
DSCA_RS21020	COG2204	response regulator
DSCA_RS21030	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DSCA_RS21035	COG0459	protein refolding
DSCA_RS21060	COG1278	Cold shock
DSCA_RS21065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DSCA_RS21095	COG0534	Mate efflux family protein
DSCA_RS21105	COG2030	dehydratase
DSCA_RS21105	COG1012	belongs to the aldehyde dehydrogenase family
DSCA_RS21110	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DSCA_RS21115	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DSCA_RS21120	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DSCA_RS21145	COG3246	L-lysine catabolic process to acetate
DSCA_RS21150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DSCA_RS21155	COG2031	fatty acid transporter
DSCA_RS21165	COG3530	Putative quorum-sensing-regulated virulence factor
DSCA_RS21170	COG4181	ATPase activity
DSCA_RS21175	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
DSCA_RS21190	COG4302	ethanolamine ammonia-lyase activity
DSCA_RS21195	COG4303	Ethanolamine ammonia lyase large subunit
DSCA_RS21205	COG0702	epimerase
DSCA_RS21260	COG1272	protein, Hemolysin III
DSCA_RS21265	COG0668	transmembrane transport
DSCA_RS21275	COG3422	double-strand break repair
DSCA_RS21300	COG2204	response regulator
DSCA_RS21310	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DSCA_RS21310	COG2199	diguanylate cyclase activity
DSCA_RS21315	COG0484	heat shock protein binding
DSCA_RS21320	COG0489	protein tyrosine kinase activity
DSCA_RS21325	COG0735	belongs to the Fur family
DSCA_RS21330	COG1592	Rubrerythrin
DSCA_RS21350	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
DSCA_RS21355	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DSCA_RS21360	COG0318	PFAM AMP-dependent synthetase and ligase
DSCA_RS21385	COG3141	response to X-ray
DSCA_RS21405	COG3132	Protein of unknown function, DUF480
DSCA_RS21415	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DSCA_RS21425	COG4608	Belongs to the ABC transporter superfamily
DSCA_RS21430	COG0444	Belongs to the ABC transporter superfamily
DSCA_RS21435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DSCA_RS21440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DSCA_RS21450	COG0747	negative chemotaxis
DSCA_RS21455	COG2005	Transcriptional regulator
DSCA_RS21460	COG1012	belongs to the aldehyde dehydrogenase family
DSCA_RS21465	COG1012	belongs to the aldehyde dehydrogenase family
DSCA_RS21485	COG2204	response regulator
DSCA_RS21490	COG4191	Histidine kinase
DSCA_RS21490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DSCA_RS21495	COG0446	pyridine nucleotide-disulphide oxidoreductase
DSCA_RS21495	COG1902	pentaerythritol trinitrate reductase activity
DSCA_RS21510	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DSCA_RS21510	COG1017	nitric oxide dioxygenase activity
DSCA_RS21530	COG0367	asparagine synthase
DSCA_RS21535	COG0174	glutamine synthetase
DSCA_RS21540	COG0347	Belongs to the P(II) protein family
DSCA_RS21545	COG0004	ammonium transporteR
DSCA_RS21550	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DSCA_RS21555	COG0004	ammonium transporteR
DSCA_RS21560	COG0347	Belongs to the P(II) protein family
DSCA_RS21565	COG0436	Aminotransferase
DSCA_RS21570	COG0346	lactoylglutathione lyase activity
DSCA_RS21580	COG2204	response regulator
DSCA_RS21585	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
DSCA_RS21595	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DSCA_RS21600	COG0247	lactate metabolic process
DSCA_RS21605	COG1139	Iron-sulfur cluster binding protein
DSCA_RS21615	COG0277	FAD linked oxidase domain protein
DSCA_RS21620	COG0247	lactate metabolic process
DSCA_RS21625	COG2186	Transcriptional regulator
DSCA_RS21650	COG0436	Aminotransferase
DSCA_RS21655	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DSCA_RS21665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSCA_RS21675	COG2197	response regulator
DSCA_RS21695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSCA_RS21720	COG5002	protein histidine kinase activity
DSCA_RS21725	COG1902	pentaerythritol trinitrate reductase activity
DSCA_RS21725	COG0446	pyridine nucleotide-disulphide oxidoreductase
DSCA_RS21740	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS21745	COG1024	Enoyl-CoA hydratase
DSCA_RS21800	COG4191	Histidine kinase
DSCA_RS21805	COG2204	response regulator
DSCA_RS21815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DSCA_RS21835	COG0497	DNA recombination
DSCA_RS21840	COG1070	Carbohydrate kinase
DSCA_RS21845	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DSCA_RS21870	COG2719	SpoVR family
DSCA_RS21890	COG0697	spore germination
DSCA_RS21900	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DSCA_RS21900	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DSCA_RS21905	COG0616	signal peptide processing
DSCA_RS21920	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DSCA_RS21955	COG1024	Enoyl-CoA hydratase
DSCA_RS21955	COG1250	3-hydroxyacyl-CoA dehydrogenase
DSCA_RS21960	COG0183	Belongs to the thiolase family
DSCA_RS21965	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DSCA_RS21975	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DSCA_RS22000	COG1295	ribonuclease BN
DSCA_RS22005	COG0488	(ABC) transporter
DSCA_RS22015	COG5012	cobalamin binding
DSCA_RS22020	COG5598	trimethylamine methyltransferase
DSCA_RS22025	COG3829	transcription factor binding
DSCA_RS22035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DSCA_RS22085	COG0411	ABC transporter
DSCA_RS22090	COG2197	response regulator
DSCA_RS22095	COG1611	Belongs to the LOG family
DSCA_RS22100	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSCA_RS22105	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DSCA_RS22110	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DSCA_RS22120	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DSCA_RS22125	COG1720	tRNA m6t6A37 methyltransferase activity
DSCA_RS22150	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DSCA_RS22160	COG2197	response regulator
DSCA_RS22165	COG0840	transmembrane signaling receptor activity
DSCA_RS22180	COG0514	ATP-dependent DNA helicase (RecQ)
DSCA_RS22185	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DSCA_RS22200	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DSCA_RS22215	COG0543	2 iron, 2 sulfur cluster binding
DSCA_RS22245	COG0697	spore germination
DSCA_RS22260	COG3852	Histidine kinase
DSCA_RS22265	COG0745	RESPONSE REGULATOR receiver
DSCA_RS22280	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DSCA_RS22285	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DSCA_RS22290	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DSCA_RS22305	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DSCA_RS22330	COG5002	protein histidine kinase activity
DSCA_RS22330	COG0784	Response regulator, receiver
DSCA_RS22330	COG2205	protein histidine kinase activity
DSCA_RS22340	COG1082	Xylose isomerase domain protein TIM barrel
DSCA_RS22350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DSCA_RS22355	COG0601	transmembrane transport
DSCA_RS22360	COG0747	negative chemotaxis
DSCA_RS22365	COG2188	Transcriptional regulator
DSCA_RS22405	COG5598	trimethylamine methyltransferase
DSCA_RS22415	COG2186	Transcriptional regulator
DSCA_RS22445	COG0247	lactate metabolic process
DSCA_RS22450	COG1139	Iron-sulfur cluster binding protein
DSCA_RS22455	COG1556	Lactate utilization protein
DSCA_RS22460	COG0517	IMP dehydrogenase activity
DSCA_RS22490	COG0318	PFAM AMP-dependent synthetase and ligase
DSCA_RS22520	COG1946	Acyl-CoA thioesterase
DSCA_RS22540	COG0667	Aldo Keto reductase
DSCA_RS22575	COG1028	Short-chain dehydrogenase reductase Sdr
DSCA_RS22585	COG0583	DNA-binding transcription factor activity
DSCA_RS22590	COG3829	transcription factor binding
DSCA_RS22605	COG5012	cobalamin binding
DSCA_RS22690	COG2186	Transcriptional regulator
DSCA_RS22695	COG0686	Belongs to the AlaDH PNT family
DSCA_RS22715	COG3360	Dodecin
DSCA_RS22725	COG0745	RESPONSE REGULATOR receiver
DSCA_RS22765	COG2223	nitrite transmembrane transporter activity
DSCA_RS22775	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DSCA_RS22780	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DSCA_RS22810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DSCA_RS22820	COG4608	Belongs to the ABC transporter superfamily
DSCA_RS22825	COG0444	Belongs to the ABC transporter superfamily
DSCA_RS22830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DSCA_RS22835	COG0601	transmembrane transport
DSCA_RS22840	COG0747	negative chemotaxis
DSCA_RS22895	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DSCA_RS22900	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DSCA_RS22905	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DSCA_RS22910	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DSCA_RS22915	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DSCA_RS22920	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DSCA_RS22925	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DSCA_RS22935	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DSCA_RS22965	COG0506	proline dehydrogenase activity
DSCA_RS22970	COG3437	response regulator, receiver
DSCA_RS22970	COG2770	Histidine kinase
DSCA_RS22975	COG1910	domain protein
DSCA_RS22980	COG2998	abc-type tungstate transport system, permease component
DSCA_RS22985	COG4662	Binding-protein-dependent transport system inner membrane component
DSCA_RS23010	COG1528	Iron-storage protein
DSCA_RS23015	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DSCA_RS23030	COG0668	transmembrane transport
DSCA_RS23035	COG4191	Histidine kinase
DSCA_RS23035	COG0784	Response regulator, receiver
DSCA_RS23060	COG2186	Transcriptional regulator
DSCA_RS23070	COG3938	Belongs to the proline racemase family
DSCA_RS23075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DSCA_RS23080	COG2226	methyltransferase
DSCA_RS23090	COG0725	ABC transporter, periplasmic molybdate-binding protein
DSCA_RS23095	COG4208	sulfate ABC transporter
DSCA_RS23100	COG3842	ATPase activity
DSCA_RS23105	COG0667	Aldo Keto reductase
DSCA_RS23115	COG0667	Aldo Keto reductase
DSCA_RS23135	COG3344	reverse transcriptase
DSCA_RS23140	COG1704	LemA family
DSCA_RS23145	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DSCA_RS23155	COG1473	amidohydrolase
DSCA_RS23160	COG0700	Nucleoside recognition
DSCA_RS23165	COG0045	succinate-CoA ligase (ADP-forming) activity
DSCA_RS23165	COG1042	CoA-binding domain protein
DSCA_RS23165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DSCA_RS23170	COG1024	Enoyl-CoA hydratase
DSCA_RS23175	COG0667	Aldo Keto reductase
DSCA_RS23180	COG0348	domain, Protein
DSCA_RS23195	COG1902	pentaerythritol trinitrate reductase activity
DSCA_RS23205	COG2340	Cysteine-rich secretory protein family
DSCA_RS23245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DSCA_RS23275	COG0427	acetyl-CoA hydrolase
DSCA_RS23280	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DSCA_RS23285	COG0697	spore germination
DSCA_RS23305	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DSCA_RS23310	COG0745	RESPONSE REGULATOR receiver
DSCA_RS23315	COG3239	Fatty acid desaturase
DSCA_RS23320	COG0840	transmembrane signaling receptor activity
DSCA_RS23325	COG4771	TonB-dependent receptor
DSCA_RS23335	COG0784	Response regulator, receiver
DSCA_RS23335	COG2205	protein histidine kinase activity
DSCA_RS23335	COG5002	protein histidine kinase activity
DSCA_RS23360	COG2193	ferroxidase activity
DSCA_RS23365	COG0646	methionine synthase
DSCA_RS23365	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DSCA_RS23390	COG1643	Atp-dependent helicase
DSCA_RS23395	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DSCA_RS23415	COG0003	Pfam Anion-transporting ATPase
DSCA_RS23430	COG1966	Carbon starvation protein
DSCA_RS23435	COG4566	intracellular signal transduction
DSCA_RS23440	COG1522	sequence-specific DNA binding
DSCA_RS23445	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DSCA_RS23455	COG2204	response regulator
DSCA_RS23460	COG5002	protein histidine kinase activity
DSCA_RS23465	COG0469	pyruvate kinase activity
DSCA_RS23485	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DSCA_RS23490	COG1592	Rubrerythrin
DSCA_RS23510	COG0183	Belongs to the thiolase family
DSCA_RS23515	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS23520	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS23530	COG1309	transcriptional regulator
DSCA_RS23550	COG0318	PFAM AMP-dependent synthetase and ligase
DSCA_RS23555	COG2030	dehydratase
DSCA_RS23560	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS23620	COG0697	spore germination
DSCA_RS23630	COG0456	acetyltransferase
DSCA_RS23640	COG2188	Transcriptional regulator
DSCA_RS23645	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DSCA_RS23650	COG2986	histidine ammonia-lyase
DSCA_RS23700	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DSCA_RS23705	COG0432	Pfam Uncharacterised protein family UPF0047
DSCA_RS23720	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DSCA_RS23730	COG1473	amidohydrolase
DSCA_RS23735	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DSCA_RS23750	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DSCA_RS23755	COG0204	Acyl-transferase
DSCA_RS23790	COG0653	protein targeting
DSCA_RS23800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSCA_RS23850	COG2030	dehydratase
DSCA_RS23850	COG1012	belongs to the aldehyde dehydrogenase family
DSCA_RS23880	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DSCA_RS23885	COG1410	methionine synthase
DSCA_RS23885	COG0646	methionine synthase
DSCA_RS23900	COG2130	NADP-dependent
DSCA_RS23935	COG1335	isochorismatase
DSCA_RS23940	COG0537	adenosine 5'-monophosphoramidase activity
DSCA_RS23975	COG3021	interspecies interaction between organisms
DSCA_RS24010	COG0745	RESPONSE REGULATOR receiver
DSCA_RS24060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DSCA_RS24065	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DSCA_RS24070	COG1333	cytochrome c biogenesis protein
DSCA_RS24140	COG0860	N-Acetylmuramoyl-L-alanine amidase
DSCA_RS24150	COG0544	peptidyl-prolyl cis-trans isomerase activity
DSCA_RS24155	COG0740	serine-type endopeptidase activity
DSCA_RS24160	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DSCA_RS24165	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DSCA_RS24215	COG0366	Alpha amylase catalytic
DSCA_RS24230	COG0297	glycogen (starch) synthase activity
DSCA_RS24235	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DSCA_RS24245	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DSCA_RS24285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DSCA_RS24305	COG0066	3-isopropylmalate dehydratase activity
DSCA_RS24310	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DSCA_RS24315	COG0028	Belongs to the TPP enzyme family
DSCA_RS24325	COG0129	dihydroxy-acid dehydratase activity
DSCA_RS24335	COG1968	undecaprenyl-diphosphatase activity
DSCA_RS24350	COG1910	domain protein
DSCA_RS24355	COG0303	'Molybdopterin
DSCA_RS24370	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DSCA_RS24405	COG1620	l-lactate permease
DSCA_RS24415	COG2186	Transcriptional regulator
DSCA_RS24430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DSCA_RS24435	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DSCA_RS24440	COG0444	Belongs to the ABC transporter superfamily
DSCA_RS24445	COG4608	Belongs to the ABC transporter superfamily
DSCA_RS24455	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DSCA_RS24460	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
DSCA_RS24465	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
DSCA_RS24470	COG0427	acetyl-CoA hydrolase
DSCA_RS24475	COG0517	IMP dehydrogenase activity
DSCA_RS24510	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
DSCA_RS24515	COG0347	Belongs to the P(II) protein family
DSCA_RS24520	COG0347	Belongs to the P(II) protein family
DSCA_RS24545	COG0535	radical SAM domain protein
DSCA_RS24545	COG1433	Dinitrogenase iron-molybdenum cofactor
DSCA_RS24565	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DSCA_RS24600	COG4608	Belongs to the ABC transporter superfamily
DSCA_RS24605	COG0444	Belongs to the ABC transporter superfamily
DSCA_RS24610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DSCA_RS24615	COG0601	transmembrane transport
DSCA_RS24620	COG0747	negative chemotaxis
DSCA_RS24640	COG3842	ATPase activity
DSCA_RS24650	COG1177	transmembrane transport
DSCA_RS24680	COG4974	Belongs to the 'phage' integrase family
DSCA_RS24685	COG0582	viral genome integration into host DNA
DSCA_RS24690	COG4974	Belongs to the 'phage' integrase family
DSCA_RS24695	COG1272	protein, Hemolysin III
DSCA_RS24720	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DSCA_RS24740	COG1837	Belongs to the UPF0109 family
DSCA_RS24760	COG0438	transferase activity, transferring glycosyl groups
DSCA_RS24765	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
DSCA_RS24770	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
DSCA_RS24775	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DSCA_RS24790	COG4974	Belongs to the 'phage' integrase family
DSCA_RS24805	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DSCA_RS24810	COG2223	nitrite transmembrane transporter activity
DSCA_RS24815	COG0646	methionine synthase
DSCA_RS24815	COG1410	methionine synthase
DSCA_RS24830	COG3604	Transcriptional regulator
DSCA_RS24840	COG2176	DNA-directed DNA polymerase activity
DSCA_RS24850	COG0840	transmembrane signaling receptor activity
DSCA_RS24865	COG1942	4-Oxalocrotonate Tautomerase
DSCA_RS24880	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DSCA_RS24895	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DSCA_RS24905	COG3290	protein histidine kinase activity
DSCA_RS24905	COG3829	transcription factor binding
DSCA_RS24910	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DSCA_RS24920	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DSCA_RS24925	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DSCA_RS24975	COG1120	ATPase activity
DSCA_RS24980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DSCA_RS24995	COG3344	reverse transcriptase
DSCA_RS25020	COG4206	TonB-dependent receptor
DSCA_RS25030	COG0848	biopolymer transport protein
DSCA_RS25035	COG0811	peptide transport
DSCA_RS25055	COG0023	Translation Initiation Factor
DSCA_RS25095	COG1917	Cupin 2, conserved barrel domain protein
DSCA_RS25095	COG1396	sequence-specific DNA binding
DSCA_RS25125	COG2204	response regulator
DSCA_RS25130	COG2204	response regulator
DSCA_RS25145	COG2204	response regulator
DSCA_RS25165	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DSCA_RS25170	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DSCA_RS25175	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DSCA_RS25180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DSCA_RS25185	COG0318	PFAM AMP-dependent synthetase and ligase
DSCA_RS25210	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DSCA_RS25215	COG5598	trimethylamine methyltransferase
DSCA_RS25230	COG0488	(ABC) transporter
DSCA_RS25295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DSCA_RS25310	COG0140	phosphoribosyl-ATP diphosphatase activity
DSCA_RS25315	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DSCA_RS25325	COG1331	Highly conserved protein containing a thioredoxin domain
DSCA_RS25370	COG4656	Part of a membrane complex involved in electron transport
DSCA_RS25375	COG4658	electron transport chain
DSCA_RS25380	COG4659	FMN binding
DSCA_RS25385	COG4660	Part of a membrane complex involved in electron transport
DSCA_RS25390	COG4657	Part of a membrane complex involved in electron transport
DSCA_RS25395	COG2878	Part of a membrane complex involved in electron transport
DSCA_RS25400	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DSCA_RS25415	COG3707	response regulator
DSCA_RS25425	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DSCA_RS25430	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DSCA_RS25440	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
DSCA_RS25445	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DSCA_RS25485	COG1309	transcriptional regulator
DSCA_RS25490	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS25495	COG0318	PFAM AMP-dependent synthetase and ligase
DSCA_RS25500	COG0247	lactate metabolic process
DSCA_RS25500	COG2181	nitrate reductase activity
DSCA_RS25525	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DSCA_RS25535	COG3005	denitrification pathway
DSCA_RS25555	COG4783	chaperone-mediated protein folding
DSCA_RS25560	COG1192	Involved in chromosome partitioning
DSCA_RS25565	COG1475	DNA binding
DSCA_RS25585	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DSCA_RS25590	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DSCA_RS25610	COG0339	signal peptide processing
DSCA_RS25665	COG0826	peptidase U32
DSCA_RS25680	COG0658	competence protein
DSCA_RS25680	COG2333	competence protein COMEC
DSCA_RS25720	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
DSCA_RS25725	COG4191	Histidine kinase
DSCA_RS25730	COG2204	response regulator
DSCA_RS25765	COG1752	Esterase of the alpha-beta hydrolase superfamily
DSCA_RS25770	COG0204	Acyl-transferase
DSCA_RS25775	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DSCA_RS25775	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DSCA_RS25780	COG2186	Transcriptional regulator
DSCA_RS25785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DSCA_RS25785	COG1042	CoA-binding domain protein
DSCA_RS25785	COG0045	succinate-CoA ligase (ADP-forming) activity
DSCA_RS25790	COG0427	acetyl-CoA hydrolase
DSCA_RS25805	COG1691	(AIR) carboxylase
DSCA_RS25815	COG0840	transmembrane signaling receptor activity
DSCA_RS25840	COG2116	formate transmembrane transporter activity
DSCA_RS25850	COG1122	ATPase activity
DSCA_RS25860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DSCA_RS25865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DSCA_RS25875	COG0531	amino acid
DSCA_RS25880	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DSCA_RS25910	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DSCA_RS25915	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DSCA_RS25920	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DSCA_RS25930	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DSCA_RS25930	COG0574	Belongs to the PEP-utilizing enzyme family
DSCA_RS25950	COG0513	Belongs to the DEAD box helicase family
DSCA_RS26035	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DSCA_RS26100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DSCA_RS26105	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DSCA_RS26140	COG0210	DNA helicase
DSCA_RS26150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DSCA_RS26255	COG3604	Transcriptional regulator
DSCA_RS26335	COG2258	MOSC domain
DSCA_RS26340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DSCA_RS26340	COG1017	nitric oxide dioxygenase activity
DSCA_RS26365	COG3604	Transcriptional regulator
DSCA_RS26400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DSCA_RS26450	COG2226	methyltransferase
DSCA_RS26455	COG0438	transferase activity, transferring glycosyl groups
DSCA_RS26460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DSCA_RS26475	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DSCA_RS26485	COG3706	GGDEF domain
DSCA_RS26495	COG0318	PFAM AMP-dependent synthetase and ligase
DSCA_RS26515	COG0693	protein deglycase activity
DSCA_RS26525	COG2197	response regulator
DSCA_RS26530	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DSCA_RS26540	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DSCA_RS26545	COG1028	Short-chain dehydrogenase reductase Sdr
DSCA_RS26550	COG0318	PFAM AMP-dependent synthetase and ligase
DSCA_RS26560	COG1063	alcohol dehydrogenase
DSCA_RS26565	COG0346	lactoylglutathione lyase activity
DSCA_RS26580	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DSCA_RS26585	COG1028	Short-chain dehydrogenase reductase Sdr
DSCA_RS26600	COG4191	Histidine kinase
DSCA_RS26620	COG0133	tryptophan synthase activity
DSCA_RS26625	COG0159	tryptophan synthase activity
DSCA_RS26630	COG1454	alcohol dehydrogenase
DSCA_RS26645	COG1837	Belongs to the UPF0109 family
DSCA_RS26650	COG1538	Outer membrane efflux protein
DSCA_RS26655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSCA_RS26680	COG0432	Pfam Uncharacterised protein family UPF0047
DSCA_RS26685	COG2920	part of a sulfur-relay system
DSCA_RS26690	COG0543	2 iron, 2 sulfur cluster binding
DSCA_RS26715	COG5002	protein histidine kinase activity
DSCA_RS26730	COG0509	glycine decarboxylation via glycine cleavage system
DSCA_RS26735	COG0509	glycine decarboxylation via glycine cleavage system
DSCA_RS26745	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DSCA_RS26775	COG2048	Heterodisulfide reductase, subunit B
DSCA_RS26785	COG2204	response regulator
DSCA_RS26825	COG2204	response regulator
DSCA_RS26830	COG5002	protein histidine kinase activity
DSCA_RS26835	COG2050	protein possibly involved in aromatic compounds catabolism
DSCA_RS26845	COG2937	Belongs to the GPAT DAPAT family
DSCA_RS26855	COG1674	ftsk spoiiie
DSCA_RS26885	COG1309	transcriptional regulator
DSCA_RS26890	COG0471	metal ion transport
DSCA_RS26890	COG3273	potassium ion transport
DSCA_RS26895	COG1024	Enoyl-CoA hydratase
DSCA_RS26900	COG0840	transmembrane signaling receptor activity
DSCA_RS26925	COG0840	transmembrane signaling receptor activity
DSCA_RS26940	COG0504	CTP synthase activity
DSCA_RS26950	COG0148	phosphopyruvate hydratase activity
DSCA_RS26960	COG0577	efflux transmembrane transporter activity
DSCA_RS26960	COG1136	(ABC) transporter
DSCA_RS26965	COG0577	efflux transmembrane transporter activity
DSCA_RS26965	COG1136	(ABC) transporter
DSCA_RS26985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSCA_RS26990	COG1151	hydroxylamine reductase activity
DSCA_RS27030	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DSCA_RS27035	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DSCA_RS27040	COG0531	amino acid
DSCA_RS27055	COG2755	lipolytic protein G-D-S-L family
DSCA_RS27075	COG0745	RESPONSE REGULATOR receiver
DSCA_RS27080	COG2205	protein histidine kinase activity
DSCA_RS27085	COG1994	Peptidase M50
DSCA_RS27120	COG3457	Alanine racemase
DSCA_RS27145	COG1272	protein, Hemolysin III
DSCA_RS27150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSCA_RS27155	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DSCA_RS27170	COG0585	pseudouridine synthase activity
DSCA_RS27210	COG0438	transferase activity, transferring glycosyl groups
DSCA_RS27215	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DSCA_RS27230	COG1032	radical SAM domain protein
DSCA_RS27240	COG0517	IMP dehydrogenase activity
DSCA_RS27265	COG4191	Histidine kinase
DSCA_RS27270	COG2204	response regulator
DSCA_RS27280	COG1309	transcriptional regulator
DSCA_RS27295	COG2197	response regulator
DSCA_RS27300	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DSCA_RS27305	COG0512	Glutamine amidotransferase of anthranilate synthase
DSCA_RS27310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DSCA_RS27315	COG0134	indole-3-glycerol-phosphate synthase activity
DSCA_RS27320	COG0135	phosphoribosylanthranilate isomerase activity
DSCA_RS27325	COG3089	Belongs to the UPF0270 family
DSCA_RS27330	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DSCA_RS27335	COG2321	neutral zinc metallopeptidase
DSCA_RS27350	COG0714	Associated with various cellular activities
DSCA_RS27370	COG5012	cobalamin binding
DSCA_RS27375	COG0410	ABC transporter
DSCA_RS27405	COG5598	trimethylamine methyltransferase
DSCA_RS27410	COG5598	trimethylamine methyltransferase
DSCA_RS27425	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DSCA_RS27430	COG0745	RESPONSE REGULATOR receiver
DSCA_RS27440	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DSCA_RS27455	COG0351	phosphomethylpyrimidine kinase
DSCA_RS27455	COG0352	thiamine-phosphate diphosphorylase activity
DSCA_RS27470	COG0602	queuosine metabolic process
DSCA_RS27480	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DSCA_RS27495	COG0785	Cytochrome C biogenesis protein
DSCA_RS27505	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DSCA_RS27510	COG2186	Transcriptional regulator
DSCA_RS27570	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DSCA_RS27580	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DSCA_RS27585	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DSCA_RS27590	COG0037	tRNA processing
DSCA_RS27605	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DSCA_RS27610	COG0443	Heat shock 70 kDa protein
DSCA_RS27625	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DSCA_RS27635	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DSCA_RS27645	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DSCA_RS27650	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DSCA_RS27655	COG0193	aminoacyl-tRNA hydrolase activity
DSCA_RS27660	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DSCA_RS27670	COG0564	pseudouridine synthase activity
DSCA_RS27680	COG4657	Part of a membrane complex involved in electron transport
DSCA_RS27685	COG4660	Part of a membrane complex involved in electron transport
DSCA_RS27690	COG4659	FMN binding
DSCA_RS27715	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DSCA_RS27720	COG1234	tRNA 3'-trailer cleavage
DSCA_RS27725	COG2264	protein methyltransferase activity
DSCA_RS27730	COG0517	IMP dehydrogenase activity
DSCA_RS27755	COG3485	protocatechuate 3,4-dioxygenase
DSCA_RS27765	COG3385	transposase activity
DSCA_RS27830	COG2133	pyrroloquinoline quinone binding
DSCA_RS27835	COG3409	Peptidoglycan-binding domain 1 protein
DSCA_RS27835	COG3267	Type II secretory pathway component ExeA
DSCA_RS27840	COG2358	TRAP transporter, solute receptor (TAXI family
DSCA_RS27885	COG4657	Part of a membrane complex involved in electron transport
DSCA_RS27890	COG4660	Part of a membrane complex involved in electron transport
DSCA_RS27895	COG4659	FMN binding
DSCA_RS27900	COG4658	electron transport chain
DSCA_RS27905	COG4656	Part of a membrane complex involved in electron transport
DSCA_RS27915	COG0243	molybdopterin cofactor binding
DSCA_RS27930	COG2204	response regulator
DSCA_RS27935	COG4566	intracellular signal transduction
DSCA_RS27940	COG4191	Histidine kinase
DSCA_RS27945	COG2204	response regulator
DSCA_RS27960	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSCA_RS28000	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DSCA_RS28005	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DSCA_RS28010	COG0228	four-way junction DNA binding
DSCA_RS28015	COG1837	Belongs to the UPF0109 family
DSCA_RS28020	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DSCA_RS28025	COG0336	Belongs to the RNA methyltransferase TrmD family
DSCA_RS28030	COG4752	Belongs to the RNA methyltransferase TrmD family
DSCA_RS28035	COG0335	large ribosomal subunit rRNA binding
DSCA_RS28040	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DSCA_RS28045	COG0792	nuclease activity
DSCA_RS28050	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DSCA_RS28055	COG2091	lysine biosynthetic process via aminoadipic acid
DSCA_RS28060	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DSCA_RS28090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DSCA_RS28110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DSCA_RS28120	COG3829	transcription factor binding
DSCA_RS28130	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DSCA_RS28135	COG1802	Transcriptional regulator
DSCA_RS28145	COG2414	aldehyde ferredoxin oxidoreductase
DSCA_RS28155	COG5598	trimethylamine methyltransferase
DSCA_RS28160	COG5012	cobalamin binding
DSCA_RS28165	COG0683	leucine binding
DSCA_RS28195	COG2086	electron transfer activity
DSCA_RS28200	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DSCA_RS28205	COG0247	lactate metabolic process
DSCA_RS28205	COG2181	nitrate reductase activity
DSCA_RS28220	COG0534	Mate efflux family protein
DSCA_RS28235	COG0601	transmembrane transport
DSCA_RS28240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DSCA_RS28260	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DSCA_RS28265	COG2204	response regulator
DSCA_RS28290	COG2204	response regulator
DSCA_RS28305	COG2204	response regulator
DSCA_RS28325	COG0668	transmembrane transport
DSCA_RS28335	COG0598	Magnesium transport protein CorA
DSCA_RS28340	COG0668	transmembrane transport
DSCA_RS28365	COG3264	Mechanosensitive ion channel
DSCA_RS28365	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
DSCA_RS28380	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DSCA_RS28405	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DSCA_RS28410	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DSCA_RS28425	COG0138	bifunctional purine biosynthesis protein purh
DSCA_RS28430	COG0138	bifunctional purine biosynthesis protein purh
DSCA_RS28435	COG1418	mRNA catabolic process
DSCA_RS28440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSCA_RS28445	COG2001	Belongs to the MraZ family
DSCA_RS28450	COG0275	rRNA processing
DSCA_RS28455	COG3116	cell division
DSCA_RS28465	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DSCA_RS28470	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DSCA_RS28475	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DSCA_RS28480	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DSCA_RS28485	COG0772	Belongs to the SEDS family
DSCA_RS28490	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DSCA_RS28495	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DSCA_RS28500	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DSCA_RS28510	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DSCA_RS28520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DSCA_RS28525	COG3829	transcription factor binding
DSCA_RS28565	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DSCA_RS28570	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DSCA_RS28575	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DSCA_RS28580	COG1238	metal cluster binding
DSCA_RS28600	COG0840	transmembrane signaling receptor activity
DSCA_RS28605	COG1193	negative regulation of DNA recombination
DSCA_RS28625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DSCA_RS28640	COG0612	Peptidase, M16
DSCA_RS28660	COG1131	(ABC) transporter
DSCA_RS28670	COG0243	molybdopterin cofactor binding
DSCA_RS28675	COG0437	4 iron, 4 sulfur cluster binding
DSCA_RS28680	COG5557	Pfam Polysulphide reductase, NrfD
DSCA_RS28705	COG0577	efflux transmembrane transporter activity
DSCA_RS28705	COG1136	(ABC) transporter
DSCA_RS28720	COG1307	EDD domain protein, DegV family
DSCA_RS28725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DSCA_RS28730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DSCA_RS28735	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DSCA_RS28750	COG3046	protein related to deoxyribodipyrimidine photolyase
DSCA_RS28760	COG1053	succinate dehydrogenase
DSCA_RS28765	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DSCA_RS28780	COG1960	acyl-CoA dehydrogenase activity
DSCA_RS28805	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DSCA_RS28830	COG0741	lytic transglycosylase activity
DSCA_RS28855	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DSCA_RS28860	COG3344	reverse transcriptase
DSCA_RS28870	COG2022	thiamine diphosphate biosynthetic process
DSCA_RS28885	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DSCA_RS28895	COG1045	serine acetyltransferase
DSCA_RS28905	COG1522	sequence-specific DNA binding
DSCA_RS28915	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DSCA_RS28920	COG2204	response regulator
DSCA_RS28925	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DSCA_RS28940	COG1028	Short-chain dehydrogenase reductase Sdr
DSCA_RS28950	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DSCA_RS28965	COG1181	Belongs to the D-alanine--D-alanine ligase family
DSCA_RS28980	COG3604	Transcriptional regulator
DSCA_RS28985	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DSCA_RS29005	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DSCA_RS29010	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DSCA_RS29015	COG3706	GGDEF domain
DSCA_RS29030	COG2186	Transcriptional regulator
DSCA_RS29035	COG5598	trimethylamine methyltransferase
DSCA_RS29045	COG0519	Catalyzes the synthesis of GMP from XMP
DSCA_RS29055	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DSCA_RS29060	COG1454	alcohol dehydrogenase
DSCA_RS29065	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DSCA_RS29075	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DSCA_RS29075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DSCA_RS29080	COG1774	PSP1 C-terminal conserved region
DSCA_RS29090	COG0776	regulation of translation
DSCA_RS29095	COG0250	Participates in transcription elongation, termination and antitermination
DSCA_RS29100	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DSCA_RS29105	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DSCA_RS29110	COG3481	metal-dependent phosphohydrolase, HD sub domain
DSCA_RS29115	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DSCA_RS29120	COG0215	cysteine-tRNA ligase activity
DSCA_RS29135	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DSCA_RS29135	COG2169	Transcriptional regulator
DSCA_RS29155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSCA_RS29205	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DSCA_RS29215	COG2211	Major facilitator Superfamily
DSCA_RS29240	COG0189	ligase activity
DSCA_RS29255	COG0189	ligase activity
DSCA_RS29265	COG0601	transmembrane transport
DSCA_RS29270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DSCA_RS29275	COG0444	Belongs to the ABC transporter superfamily
DSCA_RS29290	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DSCA_RS29290	COG0515	serine threonine protein kinase
DSCA_RS29300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSCA_RS29310	COG1024	Enoyl-CoA hydratase
DSCA_RS29320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSCA_RS29440	COG1619	proteins homologs of microcin C7 resistance protein MccF
DSCA_RS29450	COG1077	Cell shape determining protein MreB Mrl
DSCA_RS29465	COG0768	penicillin binding
DSCA_RS29470	COG0772	Belongs to the SEDS family
DSCA_RS29480	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DSCA_RS29485	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DSCA_RS29490	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DSCA_RS29495	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DSCA_RS29500	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DSCA_RS29505	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DSCA_RS29510	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DSCA_RS29530	COG1418	mRNA catabolic process
DSCA_RS29535	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DSCA_RS29590	COG3852	Histidine kinase
DSCA_RS29595	COG2204	response regulator
DSCA_RS29605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DSCA_RS29610	COG4597	amino acid ABC transporter
DSCA_RS29615	COG0765	amino acid transport
DSCA_RS29620	COG1126	abc transporter atp-binding protein
DSCA_RS29625	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DSCA_RS29630	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DSCA_RS29630	COG1672	PFAM Archaeal ATPase
DSCA_RS29640	COG1160	GTP binding
DSCA_RS29645	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DSCA_RS29660	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DSCA_RS29670	COG0842	Transport permease protein
DSCA_RS29675	COG0842	Transport permease protein
DSCA_RS29680	COG1131	(ABC) transporter
DSCA_RS29685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSCA_RS29695	COG1242	4 iron, 4 sulfur cluster binding
DSCA_RS29700	COG0445	tRNA wobble uridine modification
DSCA_RS29710	COG0390	transport system, permease component
DSCA_RS29715	COG0484	heat shock protein binding
DSCA_RS29720	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DSCA_RS29750	COG3409	Peptidoglycan-binding domain 1 protein
DSCA_RS29750	COG3267	Type II secretory pathway component ExeA
DSCA_RS29785	COG3409	Peptidoglycan-binding domain 1 protein
DSCA_RS29785	COG3267	Type II secretory pathway component ExeA
DSCA_RS29825	COG1181	Belongs to the D-alanine--D-alanine ligase family
DSCA_RS29830	COG0151	Belongs to the GarS family
DSCA_RS29835	COG0009	L-threonylcarbamoyladenylate synthase
DSCA_RS29855	COG3485	protocatechuate 3,4-dioxygenase
DSCA_RS29950	COG3620	sequence-specific DNA binding
DSCA_RS29960	COG0358	DNA primase activity
DSCA_RS29965	COG4974	Belongs to the 'phage' integrase family
DSCA_RS29970	COG4974	Belongs to the 'phage' integrase family
DSCA_RS29985	COG3620	sequence-specific DNA binding
DSCA_RS30080	COG3620	sequence-specific DNA binding
DSCA_RS30085	COG0358	DNA primase activity
DSCA_RS30115	COG0697	spore germination
DSCA_RS30125	COG2226	methyltransferase
DSCA_RS30130	COG3437	response regulator, receiver
DSCA_RS30130	COG0784	Response regulator, receiver
DSCA_RS30140	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DSCA_RS30150	COG0181	hydroxymethylbilane synthase activity
DSCA_RS30165	COG1921	L-seryl-tRNASec selenium transferase activity
DSCA_RS30175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DSCA_RS30180	COG1120	ATPase activity
DSCA_RS30190	COG1797	cobyrinic acid a,c-diamide synthase activity
DSCA_RS30210	COG1472	Belongs to the glycosyl hydrolase 3 family
DSCA_RS30215	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DSCA_RS30220	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DSCA_RS30225	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DSCA_RS30230	COG0436	Aminotransferase
DSCA_RS30245	COG0243	molybdopterin cofactor binding
DSCA_RS30250	COG1058	Belongs to the CinA family
DSCA_RS30250	COG1546	Belongs to the CinA family
DSCA_RS30260	COG3321	synthase
DSCA_RS30260	COG0604	alcohol dehydrogenase
DSCA_RS30265	COG1733	regulation of RNA biosynthetic process
DSCA_RS30285	COG2204	response regulator
DSCA_RS30300	COG0745	RESPONSE REGULATOR receiver
DSCA_RS30305	COG2204	response regulator
DSCA_RS30320	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DSCA_RS30320	COG0574	Belongs to the PEP-utilizing enzyme family
DSCA_RS30325	COG3938	Belongs to the proline racemase family
DSCA_RS30345	COG2814	Major facilitator Superfamily
DSCA_RS30350	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DSCA_RS30365	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DSCA_RS30395	COG0183	Belongs to the thiolase family
DSCA_RS30400	COG0628	permease
DSCA_RS30410	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DSCA_RS30415	COG2003	Belongs to the UPF0758 family
DSCA_RS30425	COG0126	phosphoglycerate kinase activity
DSCA_RS30440	COG2267	carboxylic ester hydrolase activity
DSCA_RS30450	COG1534	Rna-binding protein
DSCA_RS30455	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DSCA_RS30470	COG0826	peptidase U32
DSCA_RS30480	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DSCA_RS30485	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DSCA_RS30490	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DSCA_RS30500	COG1492	cobalamin metabolic process
DSCA_RS30505	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
DSCA_RS30530	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DSCA_RS30535	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DSCA_RS30545	COG2197	response regulator
DSCA_RS30550	COG0493	'glutamate synthase
DSCA_RS30550	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DSCA_RS30555	COG2414	aldehyde ferredoxin oxidoreductase
DSCA_RS30565	COG1233	COG1233 Phytoene dehydrogenase and related
DSCA_RS30585	COG0674	pyruvate-flavodoxin oxidoreductase activity
DSCA_RS30585	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DSCA_RS30585	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DSCA_RS30585	COG1013	pyruvate-flavodoxin oxidoreductase activity
DSCA_RS30590	COG0437	4 iron, 4 sulfur cluster binding
DSCA_RS30595	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DSCA_RS30615	COG0640	Transcriptional regulator
DSCA_RS30630	COG3118	belongs to the thioredoxin family
DSCA_RS30645	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DSCA_RS30650	COG0798	PFAM Bile acid sodium symporter
DSCA_RS30670	COG2201	protein-glutamate methylesterase activity
DSCA_RS30685	COG2204	response regulator
DSCA_RS30695	COG4191	Histidine kinase
DSCA_RS30720	COG0745	RESPONSE REGULATOR receiver
DSCA_RS30740	COG0277	FAD linked oxidase domain protein
DSCA_RS30750	COG0674	pyruvate-flavodoxin oxidoreductase activity
DSCA_RS30750	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DSCA_RS30755	COG1013	pyruvate-flavodoxin oxidoreductase activity
DSCA_RS30765	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DSCA_RS30790	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DSCA_RS30810	COG1234	tRNA 3'-trailer cleavage
DSCA_RS30885	COG2135	peptidase activity
DSCA_RS30900	COG0500	methyltransferase
DSCA_RS30935	COG0516	GMP reductase activity
DSCA_RS30965	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DSCA_RS30975	COG0459	protein refolding
DSCA_RS30980	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DSCA_RS31000	COG0330	HflC and HflK could
DSCA_RS31015	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DSCA_RS31035	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DSCA_RS31040	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DSCA_RS31045	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DSCA_RS31070	COG0038	chloride channel
DSCA_RS31080	COG0668	transmembrane transport
DSCA_RS31085	COG2204	response regulator
DSCA_RS31090	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DSCA_RS31095	COG2201	protein-glutamate methylesterase activity
DSCA_RS31105	COG2198	Histidine kinase
DSCA_RS31105	COG0643	Histidine kinase
DSCA_RS31115	COG1053	succinate dehydrogenase
DSCA_RS31145	COG0823	Involved in the tonB-independent uptake of proteins
DSCA_RS31150	COG2885	chlorophyll binding
DSCA_RS31160	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DSCA_RS31165	COG0632	four-way junction helicase activity
DSCA_RS31170	COG2255	four-way junction helicase activity
DSCA_RS31195	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DSCA_RS31200	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DSCA_RS31210	COG4174	ABC transporter (Permease)
DSCA_RS31215	COG4239	(ABC) transporter, permease
DSCA_RS31230	COG4608	Belongs to the ABC transporter superfamily
DSCA_RS31245	COG2414	aldehyde ferredoxin oxidoreductase
DSCA_RS31255	COG2181	nitrate reductase activity
DSCA_RS31255	COG0247	lactate metabolic process
DSCA_RS31280	COG2703	oxygen carrier activity
DSCA_RS31285	COG0674	pyruvate-flavodoxin oxidoreductase activity
DSCA_RS31285	COG1013	pyruvate-flavodoxin oxidoreductase activity
DSCA_RS31285	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DSCA_RS31285	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSCA_RS31290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DSCA_RS31305	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DSCA_RS31310	COG3604	Transcriptional regulator
DSCA_RS31320	COG2721	sulfolactate sulfo-lyase activity
DSCA_RS31335	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DSCA_RS31340	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DSCA_RS31345	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DSCA_RS31345	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DSCA_RS31350	COG2414	aldehyde ferredoxin oxidoreductase
DSCA_RS31365	COG1028	Short-chain dehydrogenase reductase Sdr
DSCA_RS31370	COG1063	alcohol dehydrogenase
DSCA_RS31390	COG0436	Aminotransferase
DSCA_RS31400	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DSCA_RS31405	COG1993	acr, cog1993
DSCA_RS31420	COG0840	transmembrane signaling receptor activity
DSCA_RS31425	COG2201	protein-glutamate methylesterase activity
DSCA_RS31430	COG0835	chemotaxis
DSCA_RS31435	COG2201	protein-glutamate methylesterase activity
DSCA_RS31440	COG0643	Histidine kinase
DSCA_RS31440	COG0784	Response regulator, receiver
DSCA_RS31440	COG2198	Histidine kinase
DSCA_RS31445	COG2201	protein-glutamate methylesterase activity
DSCA_RS31450	COG1192	Involved in chromosome partitioning
DSCA_RS31465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DSCA_RS31470	COG1116	anion transmembrane transporter activity
DSCA_RS31485	COG1100	Small GTP-binding protein
DSCA_RS31525	COG0535	radical SAM domain protein
DSCA_RS31530	COG0113	porphobilinogen synthase activity
DSCA_RS31535	COG0535	radical SAM domain protein
DSCA_RS31545	COG0613	PHP domain protein
DSCA_RS31575	COG0746	molybdenum cofactor guanylyltransferase activity
DSCA_RS31625	COG0405	Gamma-glutamyltransferase
DSCA_RS31630	COG2186	Transcriptional regulator
DSCA_RS31635	COG0745	RESPONSE REGULATOR receiver
DSCA_RS31640	COG4191	Histidine kinase
DSCA_RS31655	COG2204	response regulator
DSCA_RS31670	COG0285	dihydrofolate synthase activity
DSCA_RS31675	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DSCA_RS31680	COG0563	adenylate kinase activity
DSCA_RS31685	COG0617	tRNA 3'-terminal CCA addition
DSCA_RS31690	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DSCA_RS31695	COG0254	rRNA binding
DSCA_RS31700	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DSCA_RS31705	COG2890	protein-(glutamine-N5) methyltransferase activity
DSCA_RS31710	COG0052	Belongs to the universal ribosomal protein uS2 family
DSCA_RS31715	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DSCA_RS31720	COG0528	UMP kinase activity
DSCA_RS31725	COG0233	cytoplasmic translational termination
DSCA_RS31740	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DSCA_RS31750	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DSCA_RS31755	COG0047	phosphoribosylformylglycinamidine synthase activity
DSCA_RS31760	COG1560	Kdo2-lipid A biosynthetic process
DSCA_RS31765	COG0859	PFAM glycosyl transferase family 9
DSCA_RS31770	COG0859	PFAM glycosyl transferase family 9
DSCA_RS31775	COG1216	Glycosyl transferase, family 2
DSCA_RS31775	COG1442	glycosyl transferase family 8
DSCA_RS31800	COG0438	transferase activity, transferring glycosyl groups
DSCA_RS31805	COG1132	(ABC) transporter
DSCA_RS31815	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DSCA_RS31820	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DSCA_RS31820	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DSCA_RS31825	COG2835	tetraacyldisaccharide 4'-kinase activity
DSCA_RS31835	COG1561	YicC-like family, N-terminal region
DSCA_RS31840	COG2052	Domain of unknown function (DUF370)
DSCA_RS31845	COG0194	GDP metabolic process
DSCA_RS31850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DSCA_RS31855	COG0538	isocitrate dehydrogenase activity
DSCA_RS31860	COG1040	competence protein
DSCA_RS31870	COG0543	2 iron, 2 sulfur cluster binding
DSCA_RS31885	COG0356	it plays a direct role in the translocation of protons across the membrane
DSCA_RS31890	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DSCA_RS31895	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DSCA_RS31900	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)