locus-tag	class	description
DAES_RS00010	COG1192	Involved in chromosome partitioning
DAES_RS00020	COG1475	DNA binding
DAES_RS00030	COG0205	6-phosphofructokinase activity
DAES_RS00045	COG2226	methyltransferase
DAES_RS00060	COG0482	sulfurtransferase activity
DAES_RS00065	COG1691	(AIR) carboxylase
DAES_RS00070	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
DAES_RS00080	COG1136	(ABC) transporter
DAES_RS00080	COG0577	efflux transmembrane transporter activity
DAES_RS00120	COG0784	Response regulator, receiver
DAES_RS00120	COG3437	response regulator, receiver
DAES_RS00140	COG1215	transferase activity, transferring glycosyl groups
DAES_RS00155	COG2202	Pas domain
DAES_RS00155	COG2205	protein histidine kinase activity
DAES_RS00165	COG0784	Response regulator, receiver
DAES_RS00165	COG2198	Histidine kinase
DAES_RS00165	COG5002	protein histidine kinase activity
DAES_RS00170	COG1151	hydroxylamine reductase activity
DAES_RS00180	COG2770	Histidine kinase
DAES_RS00180	COG3437	response regulator, receiver
DAES_RS00190	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DAES_RS00195	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DAES_RS00210	COG0440	acetolactate synthase activity
DAES_RS00215	COG0280	phosphate acetyltransferase
DAES_RS00220	COG3426	butyrate kinase activity
DAES_RS00250	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DAES_RS00255	COG1704	LemA family
DAES_RS00275	COG0583	DNA-binding transcription factor activity
DAES_RS00280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DAES_RS00290	COG0114	fumarate hydratase activity
DAES_RS00305	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
DAES_RS00315	COG0745	RESPONSE REGULATOR receiver
DAES_RS00320	COG5002	protein histidine kinase activity
DAES_RS00330	COG0659	secondary active sulfate transmembrane transporter activity
DAES_RS00350	COG0415	Belongs to the DNA photolyase family
DAES_RS00360	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DAES_RS00375	COG3959	Transketolase, thiamine diphosphate binding domain
DAES_RS00380	COG3958	Transketolase
DAES_RS00385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DAES_RS00395	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DAES_RS00405	COG0398	Pfam SNARE associated Golgi protein
DAES_RS00420	COG2703	oxygen carrier activity
DAES_RS00435	COG2226	methyltransferase
DAES_RS00440	COG1216	Glycosyl transferase, family 2
DAES_RS00505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DAES_RS00510	COG1088	dTDP-glucose 4,6-dehydratase activity
DAES_RS00520	COG1083	cytidylyl-transferase
DAES_RS00525	COG1215	transferase activity, transferring glycosyl groups
DAES_RS00530	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DAES_RS00545	COG4999	Histidine kinase
DAES_RS00545	COG3850	Histidine kinase
DAES_RS00545	COG3437	response regulator, receiver
DAES_RS00545	COG2205	protein histidine kinase activity
DAES_RS00550	COG3676	manually curated
DAES_RS00555	COG5433	transposase activity
DAES_RS00560	COG0840	transmembrane signaling receptor activity
DAES_RS00565	COG0784	Response regulator, receiver
DAES_RS00565	COG2205	protein histidine kinase activity
DAES_RS00575	COG2204	response regulator
DAES_RS00580	COG4191	Histidine kinase
DAES_RS00585	COG0745	RESPONSE REGULATOR receiver
DAES_RS00590	COG0574	Belongs to the PEP-utilizing enzyme family
DAES_RS00590	COG3848	Pyruvate phosphate dikinase
DAES_RS00600	COG0589	response to stress
DAES_RS00610	COG0730	response to heat
DAES_RS00630	COG0745	RESPONSE REGULATOR receiver
DAES_RS00635	COG0574	Belongs to the PEP-utilizing enzyme family
DAES_RS00635	COG3848	Pyruvate phosphate dikinase
DAES_RS00640	COG3676	manually curated
DAES_RS00645	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DAES_RS00655	COG2813	Specifically methylates the guanine in position
DAES_RS00700	COG2884	Cell division ATP-binding protein ftsE
DAES_RS00705	COG2183	response to ionizing radiation
DAES_RS00720	COG5000	phosphorelay sensor kinase activity
DAES_RS00725	COG1090	epimerase
DAES_RS00730	COG2204	response regulator
DAES_RS00735	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DAES_RS00740	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DAES_RS00765	COG0517	IMP dehydrogenase activity
DAES_RS00795	COG0437	4 iron, 4 sulfur cluster binding
DAES_RS00820	COG0303	'Molybdopterin
DAES_RS00825	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DAES_RS00830	COG1763	Mo-molybdopterin cofactor biosynthetic process
DAES_RS00835	COG0746	molybdenum cofactor guanylyltransferase activity
DAES_RS00840	COG1073	alpha beta
DAES_RS00860	COG4122	O-methyltransferase activity
DAES_RS00865	COG0731	radical SAM domain protein
DAES_RS00865	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DAES_RS00870	COG1530	ribonuclease E activity
DAES_RS00875	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DAES_RS00885	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DAES_RS00895	COG0328	RNA-DNA hybrid ribonuclease activity
DAES_RS00910	COG0577	efflux transmembrane transporter activity
DAES_RS00910	COG1136	(ABC) transporter
DAES_RS00915	COG4591	ABC-type transport system involved in lipoprotein release permease component
DAES_RS00915	COG1136	(ABC) transporter
DAES_RS00930	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DAES_RS00935	COG0330	HflC and HflK could
DAES_RS00940	COG0330	HflC and HflK could
DAES_RS00950	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DAES_RS00975	COG0438	transferase activity, transferring glycosyl groups
DAES_RS00980	COG1042	CoA-binding domain protein
DAES_RS00980	COG0045	succinate-CoA ligase (ADP-forming) activity
DAES_RS00980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DAES_RS00990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DAES_RS00995	COG0835	chemotaxis
DAES_RS01005	COG1228	amidohydrolase
DAES_RS01010	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DAES_RS01015	COG1830	Aldolase
DAES_RS01065	COG0840	transmembrane signaling receptor activity
DAES_RS01070	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DAES_RS01090	COG1705	Flagellar rod assembly protein muramidase FlgJ
DAES_RS01090	COG1388	LysM domain
DAES_RS01095	COG0084	hydrolase, TatD family'
DAES_RS01145	COG0242	peptide deformylase activity
DAES_RS01150	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DAES_RS01155	COG0124	histidyl-tRNA synthetase
DAES_RS01160	COG3383	formate dehydrogenase (NAD+) activity
DAES_RS01170	COG4603	Belongs to the binding-protein-dependent transport system permease family
DAES_RS01175	COG3845	ABC transporter
DAES_RS01180	COG1744	ABC transporter substrate-binding protein PnrA-like
DAES_RS01185	COG0326	Molecular chaperone. Has ATPase activity
DAES_RS01240	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DAES_RS01250	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DAES_RS01265	COG1360	Flagellar Motor Protein
DAES_RS01285	COG1338	Plays a role in the flagellum-specific transport system
DAES_RS01290	COG1987	bacterial-type flagellum assembly
DAES_RS01295	COG1067	ATP-dependent peptidase activity
DAES_RS01305	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DAES_RS01325	COG2208	phosphoserine phosphatase activity
DAES_RS01350	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DAES_RS01360	COG0018	arginyl-trna synthetase
DAES_RS01380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DAES_RS01395	COG0166	Belongs to the GPI family
DAES_RS01430	COG0601	transmembrane transport
DAES_RS01450	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DAES_RS01455	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DAES_RS01465	COG1027	Aspartate ammonia-lyase
DAES_RS01485	COG4624	Iron only hydrogenase large subunit, C-terminal domain
DAES_RS01485	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DAES_RS01490	COG2207	Transcriptional regulator
DAES_RS01495	COG0697	spore germination
DAES_RS01500	COG0697	spore germination
DAES_RS01525	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DAES_RS01530	COG0438	transferase activity, transferring glycosyl groups
DAES_RS01540	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DAES_RS01550	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DAES_RS01550	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DAES_RS01560	COG0215	cysteine-tRNA ligase activity
DAES_RS01655	COG0697	spore germination
DAES_RS01705	COG5002	protein histidine kinase activity
DAES_RS01705	COG5001	Diguanylate cyclase
DAES_RS01705	COG3447	MASE1 domain protein
DAES_RS01730	COG0778	Nitroreductase
DAES_RS01745	COG3527	Alpha-acetolactate decarboxylase
DAES_RS01750	COG0438	transferase activity, transferring glycosyl groups
DAES_RS01765	COG0840	transmembrane signaling receptor activity
DAES_RS01780	COG5002	protein histidine kinase activity
DAES_RS01790	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
DAES_RS01810	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DAES_RS01815	COG1058	Belongs to the CinA family
DAES_RS01815	COG1546	Belongs to the CinA family
DAES_RS01825	COG0437	4 iron, 4 sulfur cluster binding
DAES_RS01850	COG5002	protein histidine kinase activity
DAES_RS01850	COG5001	Diguanylate cyclase
DAES_RS01850	COG3447	MASE1 domain protein
DAES_RS01865	COG0577	efflux transmembrane transporter activity
DAES_RS01865	COG1136	(ABC) transporter
DAES_RS01890	COG1294	oxidase, subunit
DAES_RS01895	COG1271	oxidase subunit
DAES_RS01920	COG1408	metallophosphoesterase
DAES_RS01930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DAES_RS01965	COG3181	Tripartite tricarboxylate transporter family receptor
DAES_RS02010	COG2801	Transposase and inactivated derivatives
DAES_RS02030	COG2184	nucleotidyltransferase activity
DAES_RS02185	COG4695	Portal protein
DAES_RS02240	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DAES_RS02275	COG3093	addiction module antidote protein HigA
DAES_RS02350	COG2963	transposase activity
DAES_RS02355	COG2801	Transposase and inactivated derivatives
DAES_RS02395	COG4974	Belongs to the 'phage' integrase family
DAES_RS02435	COG2963	transposase activity
DAES_RS02465	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DAES_RS02470	COG0693	protein deglycase activity
DAES_RS02475	COG0148	phosphopyruvate hydratase activity
DAES_RS02480	COG0640	Transcriptional regulator
DAES_RS02520	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DAES_RS02530	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DAES_RS02545	COG5002	protein histidine kinase activity
DAES_RS02565	COG0778	Nitroreductase
DAES_RS02570	COG1733	regulation of RNA biosynthetic process
DAES_RS02575	COG2205	protein histidine kinase activity
DAES_RS02575	COG3437	response regulator, receiver
DAES_RS02575	COG3850	Histidine kinase
DAES_RS02575	COG4999	Histidine kinase
DAES_RS02580	COG3676	manually curated
DAES_RS02610	COG1151	hydroxylamine reductase activity
DAES_RS02620	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DAES_RS02625	COG0861	Integral membrane protein TerC family
DAES_RS02630	COG0363	glucosamine-6-phosphate deaminase activity
DAES_RS02635	COG2207	Transcriptional regulator
DAES_RS02635	COG3708	Transcriptional regulator
DAES_RS02655	COG1136	(ABC) transporter
DAES_RS02675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DAES_RS02685	COG0318	PFAM AMP-dependent synthetase and ligase
DAES_RS02700	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DAES_RS02705	COG0390	transport system, permease component
DAES_RS02710	COG2204	response regulator
DAES_RS02730	COG0438	transferase activity, transferring glycosyl groups
DAES_RS02740	COG0116	Belongs to the methyltransferase superfamily
DAES_RS02740	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DAES_RS02755	COG1366	Belongs to the anti-sigma-factor antagonist family
DAES_RS02805	COG1132	(ABC) transporter
DAES_RS02810	COG4771	TonB-dependent receptor
DAES_RS02840	COG0811	peptide transport
DAES_RS02845	COG0811	peptide transport
DAES_RS02850	COG0848	biopolymer transport protein
DAES_RS02885	COG4771	TonB-dependent receptor
DAES_RS02895	COG1132	(ABC) transporter
DAES_RS02900	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DAES_RS02915	COG1846	Transcriptional regulator
DAES_RS02920	COG4172	Belongs to the ABC transporter superfamily
DAES_RS02925	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DAES_RS02930	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DAES_RS02940	COG1027	Aspartate ammonia-lyase
DAES_RS02960	COG4624	Iron only hydrogenase large subunit, C-terminal domain
DAES_RS02960	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DAES_RS02965	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DAES_RS02970	COG0531	amino acid
DAES_RS02990	COG1136	(ABC) transporter
DAES_RS03015	COG1490	D-aminoacyl-tRNA deacylase activity
DAES_RS03025	COG0720	synthase
DAES_RS03040	COG0471	metal ion transport
DAES_RS03045	COG0784	Response regulator, receiver
DAES_RS03045	COG2198	Histidine kinase
DAES_RS03045	COG2205	protein histidine kinase activity
DAES_RS03105	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DAES_RS03110	COG4585	Histidine kinase
DAES_RS03120	COG2801	Transposase and inactivated derivatives
DAES_RS03125	COG2963	transposase activity
DAES_RS03130	COG3210	domain, Protein
DAES_RS03160	COG1473	amidohydrolase
DAES_RS03165	COG1760	l-serine dehydratase
DAES_RS03175	COG3842	ATPase activity
DAES_RS03180	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DAES_RS03185	COG0395	ABC-type sugar transport system, permease component
DAES_RS03190	COG1175	transmembrane transport
DAES_RS03195	COG0647	UMP catabolic process
DAES_RS03205	COG1301	dicarboxylic acid transport
DAES_RS03220	COG0840	transmembrane signaling receptor activity
DAES_RS03250	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DAES_RS03260	COG0004	ammonium transporteR
DAES_RS03270	COG0560	Phosphoserine phosphatase
DAES_RS03270	COG3830	Belongs to the UPF0237 family
DAES_RS03285	COG0598	Magnesium transport protein CorA
DAES_RS03295	COG1280	lysine exporter protein (LysE YggA)
DAES_RS03300	COG0628	permease
DAES_RS03305	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DAES_RS03310	COG3279	Response regulator of the LytR AlgR family
DAES_RS03325	COG0427	acetyl-CoA hydrolase
DAES_RS03355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DAES_RS03360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DAES_RS03375	COG0745	RESPONSE REGULATOR receiver
DAES_RS03415	COG0436	Aminotransferase
DAES_RS03420	COG0616	signal peptide processing
DAES_RS03425	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DAES_RS03430	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
DAES_RS03435	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DAES_RS03455	COG2801	Transposase and inactivated derivatives
DAES_RS03460	COG2963	transposase activity
DAES_RS03480	COG0367	asparagine synthase
DAES_RS03495	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DAES_RS03505	COG0506	proline dehydrogenase activity
DAES_RS03510	COG3708	Transcriptional regulator
DAES_RS03510	COG2207	Transcriptional regulator
DAES_RS03525	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DAES_RS03545	COG0438	transferase activity, transferring glycosyl groups
DAES_RS03555	COG0367	asparagine synthase
DAES_RS03565	COG0438	transferase activity, transferring glycosyl groups
DAES_RS03575	COG1546	Belongs to the CinA family
DAES_RS03590	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DAES_RS03600	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DAES_RS03645	COG1797	cobyrinic acid a,c-diamide synthase activity
DAES_RS03650	COG2270	Major facilitator Superfamily
DAES_RS03655	COG2078	PFAM AMMECR1 domain protein
DAES_RS03695	COG0525	valine-tRNA ligase activity
DAES_RS03710	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DAES_RS03715	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DAES_RS03720	COG0702	epimerase
DAES_RS03730	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DAES_RS03735	COG1522	sequence-specific DNA binding
DAES_RS03740	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DAES_RS03780	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DAES_RS03785	COG0228	four-way junction DNA binding
DAES_RS03790	COG1837	Belongs to the UPF0109 family
DAES_RS03795	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DAES_RS03800	COG0336	Belongs to the RNA methyltransferase TrmD family
DAES_RS03800	COG4752	Belongs to the RNA methyltransferase TrmD family
DAES_RS03805	COG0335	large ribosomal subunit rRNA binding
DAES_RS03825	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DAES_RS03830	COG1268	BioY protein
DAES_RS03840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DAES_RS03845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DAES_RS03850	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DAES_RS03860	COG2204	response regulator
DAES_RS03885	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
DAES_RS03895	COG2048	Heterodisulfide reductase, subunit B
DAES_RS03905	COG0247	lactate metabolic process
DAES_RS03915	COG5557	Pfam Polysulphide reductase, NrfD
DAES_RS03920	COG3064	Membrane
DAES_RS03920	COG0437	4 iron, 4 sulfur cluster binding
DAES_RS03930	COG0277	FAD linked oxidase domain protein
DAES_RS03945	COG0653	protein targeting
DAES_RS03965	COG2226	methyltransferase
DAES_RS03985	COG0142	geranyltranstransferase activity
DAES_RS03990	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DAES_RS04000	COG0840	transmembrane signaling receptor activity
DAES_RS04010	COG1592	Rubrerythrin
DAES_RS04015	COG2033	superoxide reductase activity
DAES_RS04020	COG1773	rubredoxin
DAES_RS04030	COG1671	Belongs to the UPF0178 family
DAES_RS04035	COG4895	conserved protein (DUF2196)
DAES_RS04055	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DAES_RS04060	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DAES_RS04075	COG0840	transmembrane signaling receptor activity
DAES_RS04080	COG5002	protein histidine kinase activity
DAES_RS04085	COG0306	phosphate transporter
DAES_RS04100	COG0129	dihydroxy-acid dehydratase activity
DAES_RS04105	COG3547	Transposase (IS116 IS110 IS902 family)
DAES_RS04110	COG0753	catalase activity
DAES_RS04120	COG0724	RNA recognition motif
DAES_RS04130	COG2193	ferroxidase activity
DAES_RS04140	COG0481	GTPase activity
DAES_RS04175	COG1595	DNA-templated transcription, initiation
DAES_RS04195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DAES_RS04200	COG0765	amino acid transport
DAES_RS04210	COG1509	lysine 2,3-aminomutase activity
DAES_RS04280	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DAES_RS04290	COG1942	4-Oxalocrotonate Tautomerase
DAES_RS04300	COG0484	heat shock protein binding
DAES_RS04305	COG0437	4 iron, 4 sulfur cluster binding
DAES_RS04305	COG3064	Membrane
DAES_RS04310	COG5557	Pfam Polysulphide reductase, NrfD
DAES_RS04320	COG2181	nitrate reductase activity
DAES_RS04325	COG0247	lactate metabolic process
DAES_RS04330	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DAES_RS04335	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DAES_RS04340	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DAES_RS04345	COG0010	Belongs to the arginase family
DAES_RS04355	COG0196	riboflavin kinase activity
DAES_RS04360	COG4783	chaperone-mediated protein folding
DAES_RS04365	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DAES_RS04375	COG0193	aminoacyl-tRNA hydrolase activity
DAES_RS04385	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DAES_RS04395	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DAES_RS04410	COG3961	Belongs to the TPP enzyme family
DAES_RS04415	COG2205	protein histidine kinase activity
DAES_RS04420	COG0840	transmembrane signaling receptor activity
DAES_RS04425	COG2353	YceI-like domain
DAES_RS04435	COG1120	ATPase activity
DAES_RS04440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DAES_RS04465	COG1166	arginine decarboxylase activity
DAES_RS04470	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DAES_RS04480	COG2274	protein secretion by the type I secretion system
DAES_RS04485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DAES_RS04520	COG2205	protein histidine kinase activity
DAES_RS04525	COG2172	sigma factor antagonist activity
DAES_RS04530	COG3180	Ammonia monooxygenase
DAES_RS04535	COG1570	exodeoxyribonuclease VII activity
DAES_RS04540	COG0739	heme binding
DAES_RS04545	COG1722	exodeoxyribonuclease VII activity
DAES_RS04550	COG0142	geranyltranstransferase activity
DAES_RS04555	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DAES_RS04560	COG3012	SEC-C Motif Domain Protein
DAES_RS04565	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DAES_RS04585	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DAES_RS04600	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DAES_RS04610	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DAES_RS04620	COG0784	Response regulator, receiver
DAES_RS04620	COG3437	response regulator, receiver
DAES_RS04625	COG0784	Response regulator, receiver
DAES_RS04625	COG4191	Histidine kinase
DAES_RS04645	COG0513	Belongs to the DEAD box helicase family
DAES_RS04650	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DAES_RS04655	COG0724	RNA recognition motif
DAES_RS04685	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DAES_RS04725	COG0159	tryptophan synthase activity
DAES_RS04730	COG0133	tryptophan synthase activity
DAES_RS04735	COG0135	phosphoribosylanthranilate isomerase activity
DAES_RS04740	COG0134	indole-3-glycerol-phosphate synthase activity
DAES_RS04745	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DAES_RS04750	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DAES_RS04750	COG0512	Glutamine amidotransferase of anthranilate synthase
DAES_RS04755	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DAES_RS04765	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DAES_RS04775	COG1465	3-dehydroquinate synthase
DAES_RS04780	COG1830	Aldolase
DAES_RS04785	COG0004	ammonium transporteR
DAES_RS04790	COG0347	Belongs to the P(II) protein family
DAES_RS04795	COG2200	EAL domain
DAES_RS04830	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DAES_RS04835	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DAES_RS04845	COG5001	Diguanylate cyclase
DAES_RS04855	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DAES_RS04855	COG1328	CTP reductase activity
DAES_RS04865	COG0840	transmembrane signaling receptor activity
DAES_RS04875	COG0501	Belongs to the peptidase M48B family
DAES_RS04910	COG0747	negative chemotaxis
DAES_RS04915	COG0601	transmembrane transport
DAES_RS04920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DAES_RS04925	COG0444	Belongs to the ABC transporter superfamily
DAES_RS04935	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DAES_RS04960	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DAES_RS04995	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DAES_RS05000	COG2205	protein histidine kinase activity
DAES_RS05000	COG0784	Response regulator, receiver
DAES_RS05000	COG5002	protein histidine kinase activity
DAES_RS05015	COG2204	response regulator
DAES_RS05030	COG0730	response to heat
DAES_RS05035	COG2204	response regulator
DAES_RS05040	COG2204	response regulator
DAES_RS05045	COG2204	response regulator
DAES_RS05055	COG2204	response regulator
DAES_RS05060	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DAES_RS05060	COG0574	Belongs to the PEP-utilizing enzyme family
DAES_RS05065	COG0701	Predicted permease
DAES_RS05080	COG3443	Belongs to the bacterial solute-binding protein 9 family
DAES_RS05080	COG0803	Belongs to the bacterial solute-binding protein 9 family
DAES_RS05085	COG1924	4 iron, 4 sulfur cluster binding
DAES_RS05090	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
DAES_RS05100	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DAES_RS05105	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
DAES_RS05130	COG1433	Dinitrogenase iron-molybdenum cofactor
DAES_RS05130	COG0535	radical SAM domain protein
DAES_RS05150	COG0535	radical SAM domain protein
DAES_RS05150	COG1433	Dinitrogenase iron-molybdenum cofactor
DAES_RS05170	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DAES_RS05175	COG0573	inorganic phosphate transmembrane transporter activity
DAES_RS05180	COG0573	inorganic phosphate transmembrane transporter activity
DAES_RS05185	COG0840	transmembrane signaling receptor activity
DAES_RS05190	COG1032	radical SAM domain protein
DAES_RS05200	COG0513	Belongs to the DEAD box helicase family
DAES_RS05215	COG0437	4 iron, 4 sulfur cluster binding
DAES_RS05225	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DAES_RS05230	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DAES_RS05235	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
DAES_RS05240	COG4095	Psort location CytoplasmicMembrane, score
DAES_RS05245	COG0138	bifunctional purine biosynthesis protein purh
DAES_RS05250	COG0840	transmembrane signaling receptor activity
DAES_RS05265	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DAES_RS05270	COG0470	DNA polymerase III
DAES_RS05295	COG1217	gtp-binding protein TYPA
DAES_RS05305	COG1027	Aspartate ammonia-lyase
DAES_RS05325	COG2204	response regulator
DAES_RS05345	COG1620	l-lactate permease
DAES_RS05350	COG0277	FAD linked oxidase domain protein
DAES_RS05355	COG0247	lactate metabolic process
DAES_RS05360	COG0280	phosphate acetyltransferase
DAES_RS05360	COG0857	belongs to the CobB CobQ family
DAES_RS05365	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DAES_RS05370	COG1556	Lactate utilization protein
DAES_RS05375	COG1139	Iron-sulfur cluster binding protein
DAES_RS05380	COG0840	transmembrane signaling receptor activity
DAES_RS05430	COG1006	Multisubunit Na H antiporter MnhC subunit
DAES_RS05435	COG0651	ATP synthesis coupled electron transport
DAES_RS05440	COG0651	ATP synthesis coupled electron transport
DAES_RS05450	COG0651	ATP synthesis coupled electron transport
DAES_RS05480	COG4566	intracellular signal transduction
DAES_RS05500	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DAES_RS05505	COG0659	secondary active sulfate transmembrane transporter activity
DAES_RS05510	COG2204	response regulator
DAES_RS05520	COG1131	(ABC) transporter
DAES_RS05530	COG2205	protein histidine kinase activity
DAES_RS05545	COG0745	RESPONSE REGULATOR receiver
DAES_RS05550	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DAES_RS05565	COG1749	Flagellar hook protein flgE
DAES_RS05570	COG1256	bacterial-type flagellum assembly
DAES_RS05585	COG2205	protein histidine kinase activity
DAES_RS05605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DAES_RS05635	COG0577	efflux transmembrane transporter activity
DAES_RS05635	COG1136	(ABC) transporter
DAES_RS05640	COG1136	(ABC) transporter
DAES_RS05640	COG0577	efflux transmembrane transporter activity
DAES_RS05670	COG2205	protein histidine kinase activity
DAES_RS05670	COG0784	Response regulator, receiver
DAES_RS05675	COG2204	response regulator
DAES_RS05700	COG1175	transmembrane transport
DAES_RS05705	COG0395	ABC-type sugar transport system, permease component
DAES_RS05710	COG3842	ATPase activity
DAES_RS05715	COG3842	ATPase activity
DAES_RS05725	COG0243	molybdopterin cofactor binding
DAES_RS05750	COG1309	transcriptional regulator
DAES_RS05775	COG1921	L-seryl-tRNASec selenium transferase activity
DAES_RS05780	COG1362	aminopeptidase activity
DAES_RS05805	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DAES_RS05810	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DAES_RS05815	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
DAES_RS05830	COG2188	Transcriptional regulator
DAES_RS05835	COG3624	Phosphonate C-P lyase system protein PhnG
DAES_RS05845	COG3626	phosphonate metabolism
DAES_RS05850	COG3627	carbon phosphorus lyase activity
DAES_RS05855	COG4107	phosphonate C-P lyase system protein PhnK
DAES_RS05860	COG4778	phosphonate C-P lyase system protein PhnL
DAES_RS05865	COG3454	Phosphonate metabolism
DAES_RS05870	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DAES_RS05880	COG3639	organic phosphonate transmembrane transporter activity
DAES_RS05930	COG1192	Involved in chromosome partitioning
DAES_RS05940	COG0243	molybdopterin cofactor binding
DAES_RS05970	COG5002	protein histidine kinase activity
DAES_RS05975	COG2204	response regulator
DAES_RS05995	COG1639	'signal transduction protein
DAES_RS06005	COG0745	RESPONSE REGULATOR receiver
DAES_RS06010	COG1774	PSP1 C-terminal conserved region
DAES_RS06015	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DAES_RS06015	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DAES_RS06040	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DAES_RS06045	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DAES_RS06070	COG0826	peptidase U32
DAES_RS06075	COG0543	2 iron, 2 sulfur cluster binding
DAES_RS06080	COG0167	dihydroorotate dehydrogenase activity
DAES_RS06095	COG0385	Bile acid
DAES_RS06110	COG2067	long-chain fatty acid transport protein
DAES_RS06115	COG1122	ATPase activity
DAES_RS06140	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DAES_RS06150	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DAES_RS06155	COG0305	Participates in initiation and elongation during chromosome replication
DAES_RS06160	COG0359	binds to the 23S rRNA
DAES_RS06165	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DAES_RS06170	COG0360	Binds together with S18 to 16S ribosomal RNA
DAES_RS06175	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DAES_RS06180	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DAES_RS06190	COG0322	excinuclease ABC activity
DAES_RS06195	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DAES_RS06220	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DAES_RS06230	COG2198	Histidine kinase
DAES_RS06230	COG0784	Response regulator, receiver
DAES_RS06230	COG0643	Histidine kinase
DAES_RS06235	COG0835	chemotaxis
DAES_RS06235	COG0784	Response regulator, receiver
DAES_RS06245	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DAES_RS06250	COG0640	Transcriptional regulator
DAES_RS06265	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DAES_RS06270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DAES_RS06275	COG1702	phosphate starvation-inducible protein PhoH
DAES_RS06280	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DAES_RS06290	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DAES_RS06295	COG0137	argininosuccinate synthase activity
DAES_RS06300	COG0165	Argininosuccinate lyase
DAES_RS06305	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DAES_RS06310	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DAES_RS06315	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DAES_RS06325	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DAES_RS06330	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DAES_RS06340	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DAES_RS06365	COG2022	thiamine diphosphate biosynthetic process
DAES_RS06370	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DAES_RS06380	COG0352	thiamine-phosphate diphosphorylase activity
DAES_RS06385	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DAES_RS06410	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DAES_RS06430	COG0463	Glycosyl transferase, family 2
DAES_RS06445	COG0671	phosphoesterase, PA-phosphatase related
DAES_RS06450	COG0438	transferase activity, transferring glycosyl groups
DAES_RS06465	COG2045	Belongs to the ComB family
DAES_RS06480	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DAES_RS06485	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DAES_RS06490	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DAES_RS06495	COG0649	NAD binding
DAES_RS06500	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DAES_RS06505	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DAES_RS06510	COG0839	Belongs to the complex I subunit 6 family
DAES_RS06515	COG0713	ATP synthesis coupled electron transport
DAES_RS06520	COG0651	ATP synthesis coupled electron transport
DAES_RS06530	COG0651	ATP synthesis coupled electron transport
DAES_RS06540	COG1007	ATP synthesis coupled electron transport
DAES_RS06560	COG0012	GTP binding
DAES_RS06565	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DAES_RS06570	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DAES_RS06585	COG2827	Endonuclease containing a URI domain
DAES_RS06590	COG0488	(ABC) transporter
DAES_RS06595	COG0494	nUDIX hydrolase
DAES_RS06600	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DAES_RS06605	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DAES_RS06610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DAES_RS06625	COG1091	dTDP-4-dehydrorhamnose reductase activity
DAES_RS06635	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DAES_RS06650	COG4662	Binding-protein-dependent transport system inner membrane component
DAES_RS06655	COG2998	abc-type tungstate transport system, permease component
DAES_RS06665	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DAES_RS06675	COG2414	aldehyde ferredoxin oxidoreductase
DAES_RS06680	COG3676	manually curated
DAES_RS06695	COG2204	response regulator
DAES_RS06725	COG4657	Part of a membrane complex involved in electron transport
DAES_RS06730	COG4660	Part of a membrane complex involved in electron transport
DAES_RS06740	COG4658	electron transport chain
DAES_RS06750	COG0484	heat shock protein binding
DAES_RS06765	COG0492	ferredoxin-NADP+ reductase activity
DAES_RS06770	COG2205	protein histidine kinase activity
DAES_RS06770	COG0784	Response regulator, receiver
DAES_RS06785	COG0745	RESPONSE REGULATOR receiver
DAES_RS06805	COG2920	part of a sulfur-relay system
DAES_RS06810	COG0254	rRNA binding
DAES_RS06815	COG3872	metal-dependent enzyme
DAES_RS06820	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DAES_RS06825	COG2890	protein-(glutamine-N5) methyltransferase activity
DAES_RS06830	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DAES_RS06860	COG1191	sigma factor activity
DAES_RS06875	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DAES_RS06880	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DAES_RS06885	COG1684	flagellar biosynthetic protein fliR
DAES_RS06890	COG0739	heme binding
DAES_RS06895	COG0037	tRNA processing
DAES_RS06905	COG1758	RNA polymerase activity
DAES_RS06910	COG0484	heat shock protein binding
DAES_RS06915	COG0315	cyclic pyranopterin monophosphate synthase activity
DAES_RS06920	COG0107	imidazoleglycerol-phosphate synthase activity
DAES_RS06925	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DAES_RS06930	COG0484	heat shock protein binding
DAES_RS06945	COG0006	proline dipeptidase activity
DAES_RS06955	COG1454	alcohol dehydrogenase
DAES_RS06990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DAES_RS06990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DAES_RS07005	COG0842	Transport permease protein
DAES_RS07010	COG1131	(ABC) transporter
DAES_RS07030	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DAES_RS07035	COG4591	ABC-type transport system involved in lipoprotein release permease component
DAES_RS07040	COG1136	(ABC) transporter
DAES_RS07045	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DAES_RS07055	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DAES_RS07065	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DAES_RS07070	COG3494	Protein of unknown function (DUF1009)
DAES_RS07085	COG1295	ribonuclease BN
DAES_RS07095	COG0343	queuine tRNA-ribosyltransferase activity
DAES_RS07100	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DAES_RS07105	COG1324	tolerance protein
DAES_RS07110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DAES_RS07120	COG2046	Belongs to the sulfate adenylyltransferase family
DAES_RS07120	COG0529	Catalyzes the synthesis of activated sulfate
DAES_RS07145	COG0848	biopolymer transport protein
DAES_RS07155	COG0823	Involved in the tonB-independent uptake of proteins
DAES_RS07165	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DAES_RS07175	COG0424	maF-like protein
DAES_RS07185	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DAES_RS07190	COG0837	glucose binding
DAES_RS07195	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DAES_RS07205	COG4603	Belongs to the binding-protein-dependent transport system permease family
DAES_RS07210	COG1079	Belongs to the binding-protein-dependent transport system permease family
DAES_RS07215	COG3845	ABC transporter
DAES_RS07220	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DAES_RS07240	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
DAES_RS07250	COG0436	Aminotransferase
DAES_RS07260	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DAES_RS07265	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DAES_RS07270	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DAES_RS07275	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DAES_RS07290	COG1013	pyruvate-flavodoxin oxidoreductase activity
DAES_RS07295	COG0488	(ABC) transporter
DAES_RS07305	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DAES_RS07310	COG0439	Biotin carboxylase
DAES_RS07315	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DAES_RS07335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DAES_RS07355	COG0840	transmembrane signaling receptor activity
DAES_RS07365	COG3676	manually curated
DAES_RS07375	COG2963	transposase activity
DAES_RS07380	COG3676	manually curated
DAES_RS07390	COG0047	phosphoribosylformylglycinamidine synthase activity
DAES_RS07395	COG0504	CTP synthase activity
DAES_RS07405	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DAES_RS07420	COG1137	ATPase activity
DAES_RS07425	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DAES_RS07435	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DAES_RS07440	COG1660	Displays ATPase and GTPase activities
DAES_RS07450	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DAES_RS07460	COG1227	inorganic diphosphatase activity
DAES_RS07465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DAES_RS07475	COG0776	regulation of translation
DAES_RS07490	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DAES_RS07495	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DAES_RS07505	COG0445	tRNA wobble uridine modification
DAES_RS07510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DAES_RS07520	COG0402	S-adenosylhomocysteine deaminase activity
DAES_RS07525	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DAES_RS07530	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DAES_RS07535	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DAES_RS07540	COG0776	regulation of translation
DAES_RS07545	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DAES_RS07550	COG1610	YqeY-like protein
DAES_RS07555	COG1193	negative regulation of DNA recombination
DAES_RS07560	COG0358	DNA primase activity
DAES_RS07570	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DAES_RS07580	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DAES_RS07585	COG0105	UTP biosynthetic process
DAES_RS07590	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DAES_RS07595	COG4120	Belongs to the binding-protein-dependent transport system permease family
DAES_RS07615	COG0793	Belongs to the peptidase S41A family
DAES_RS07630	COG2264	protein methyltransferase activity
DAES_RS07640	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DAES_RS07655	COG0069	glutamate synthase activity
DAES_RS07660	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DAES_RS07665	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DAES_RS07670	COG0067	glutamate synthase
DAES_RS07680	COG1862	Preprotein translocase
DAES_RS07685	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DAES_RS07690	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DAES_RS07695	COG0563	adenylate kinase activity
DAES_RS07700	COG0037	tRNA processing
DAES_RS07710	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DAES_RS07715	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DAES_RS07720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DAES_RS07720	COG1648	precorrin-2 dehydrogenase activity
DAES_RS07730	COG4641	Protein conserved in bacteria
DAES_RS07745	COG0019	diaminopimelate decarboxylase activity
DAES_RS07755	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DAES_RS07760	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DAES_RS07780	COG3620	sequence-specific DNA binding
DAES_RS07780	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DAES_RS07780	COG0617	tRNA 3'-terminal CCA addition
DAES_RS07785	COG4974	Belongs to the 'phage' integrase family
DAES_RS07790	COG0436	Aminotransferase
DAES_RS07795	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DAES_RS07820	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DAES_RS07830	COG0126	phosphoglycerate kinase activity
DAES_RS07835	COG0456	acetyltransferase
DAES_RS07845	COG0483	inositol monophosphate 1-phosphatase activity
DAES_RS07860	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DAES_RS07875	COG1187	pseudouridine synthase activity
DAES_RS07880	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DAES_RS07885	COG1674	ftsk spoiiie
DAES_RS07890	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DAES_RS07895	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DAES_RS07900	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DAES_RS07920	COG1968	undecaprenyl-diphosphatase activity
DAES_RS07940	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DAES_RS07955	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DAES_RS08005	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DAES_RS08010	COG0358	DNA primase activity
DAES_RS08280	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DAES_RS08305	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DAES_RS08320	COG0668	transmembrane transport
DAES_RS08325	COG0501	Belongs to the peptidase M48B family
DAES_RS08360	COG3676	manually curated
DAES_RS08365	COG2189	Belongs to the N(4) N(6)-methyltransferase family
DAES_RS08380	COG5002	protein histidine kinase activity
DAES_RS08380	COG0784	Response regulator, receiver
DAES_RS08380	COG2198	Histidine kinase
DAES_RS08395	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DAES_RS08425	COG0439	Biotin carboxylase
DAES_RS08435	COG0617	tRNA 3'-terminal CCA addition
DAES_RS08445	COG0784	Response regulator, receiver
DAES_RS08445	COG2205	protein histidine kinase activity
DAES_RS08445	COG5002	protein histidine kinase activity
DAES_RS08475	COG0719	Fe-S assembly protein
DAES_RS08480	COG0396	ATPase activity
DAES_RS08490	COG0835	chemotaxis
DAES_RS08510	COG0440	acetolactate synthase activity
DAES_RS08515	COG0028	Belongs to the TPP enzyme family
DAES_RS08525	COG2249	NAD(P)H dehydrogenase (quinone) activity
DAES_RS08530	COG1067	ATP-dependent peptidase activity
DAES_RS08560	COG1104	cysteine desulfurase activity
DAES_RS08570	COG1045	serine acetyltransferase
DAES_RS08580	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DAES_RS08585	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DAES_RS08615	COG2239	Acts as a magnesium transporter
DAES_RS08630	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DAES_RS08640	COG0569	domain protein
DAES_RS08645	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DAES_RS08650	COG0072	phenylalanine-tRNA ligase activity
DAES_RS08650	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DAES_RS08665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DAES_RS08670	COG0268	Binds directly to 16S ribosomal RNA
DAES_RS08675	COG0751	glycine-tRNA ligase activity
DAES_RS08680	COG0752	glycyl-tRNA synthetase alpha subunit
DAES_RS08685	COG1381	Involved in DNA repair and RecF pathway recombination
DAES_RS08695	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DAES_RS08710	COG0835	chemotaxis
DAES_RS08725	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DAES_RS08730	COG0736	holo-[acyl-carrier-protein] synthase activity
DAES_RS08735	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DAES_RS08735	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DAES_RS08740	COG0516	GMP reductase activity
DAES_RS08740	COG0517	IMP dehydrogenase activity
DAES_RS08755	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DAES_RS08770	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DAES_RS08775	COG3481	metal-dependent phosphohydrolase, HD sub domain
DAES_RS08780	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DAES_RS08785	COG0765	amino acid transport
DAES_RS08790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DAES_RS08795	COG0765	amino acid transport
DAES_RS08810	COG0750	zinc metalloprotease
DAES_RS08815	COG2873	o-acetylhomoserine
DAES_RS08820	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DAES_RS08825	COG0444	Belongs to the ABC transporter superfamily
DAES_RS08830	COG4608	Belongs to the ABC transporter superfamily
DAES_RS08845	COG1122	ATPase activity
DAES_RS08850	COG0534	Mate efflux family protein
DAES_RS08875	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DAES_RS08885	COG2267	carboxylic ester hydrolase activity
DAES_RS08890	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
DAES_RS08895	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DAES_RS08900	COG0440	acetolactate synthase activity
DAES_RS08905	COG0028	Belongs to the TPP enzyme family
DAES_RS08915	COG1872	DUF167
DAES_RS08945	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DAES_RS08965	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DAES_RS08975	COG0742	ribosomal rna small subunit methyltransferase
DAES_RS08980	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DAES_RS08990	COG0697	spore germination
DAES_RS09005	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DAES_RS09020	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DAES_RS09045	COG0534	Mate efflux family protein
DAES_RS09050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DAES_RS09055	COG3676	manually curated
DAES_RS09060	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DAES_RS09065	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DAES_RS09080	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DAES_RS09085	COG0542	response to heat
DAES_RS09090	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DAES_RS09100	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DAES_RS09105	COG1993	acr, cog1993
DAES_RS09110	COG2201	protein-glutamate methylesterase activity
DAES_RS09115	COG0643	Histidine kinase
DAES_RS09115	COG2198	Histidine kinase
DAES_RS09120	COG0840	transmembrane signaling receptor activity
DAES_RS09130	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DAES_RS09140	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DAES_RS09145	COG0492	ferredoxin-NADP+ reductase activity
DAES_RS09150	COG3118	belongs to the thioredoxin family
DAES_RS09160	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DAES_RS09185	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DAES_RS09190	COG0489	protein tyrosine kinase activity
DAES_RS09200	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DAES_RS09220	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DAES_RS09230	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DAES_RS09240	COG0740	serine-type endopeptidase activity
DAES_RS09245	COG0544	peptidyl-prolyl cis-trans isomerase activity
DAES_RS09255	COG0351	phosphomethylpyrimidine kinase
DAES_RS09275	COG4957	zinc ion binding
DAES_RS09305	COG0017	Asparaginyl-tRNA synthetase
DAES_RS09310	COG0552	protein localization to endoplasmic reticulum
DAES_RS09315	COG0539	negative regulation of cytoplasmic translation
DAES_RS09320	COG0564	pseudouridine synthase activity
DAES_RS09330	COG1074	ATP-dependent DNA helicase activity
DAES_RS09345	COG0579	oxidoreductase
DAES_RS09350	COG2070	2-Nitropropane dioxygenase
DAES_RS09355	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DAES_RS09360	COG4974	Belongs to the 'phage' integrase family
DAES_RS09370	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DAES_RS09370	COG1418	mRNA catabolic process
DAES_RS09380	COG0758	DNA mediated transformation
DAES_RS09400	COG0643	Histidine kinase
DAES_RS09400	COG0784	Response regulator, receiver
DAES_RS09400	COG2198	Histidine kinase
DAES_RS09400	COG2198	Histidine kinase
DAES_RS09400	COG0784	Response regulator, receiver
DAES_RS09400	COG0643	Histidine kinase
DAES_RS09405	COG0745	RESPONSE REGULATOR receiver
DAES_RS09410	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DAES_RS09420	COG2201	protein-glutamate methylesterase activity
DAES_RS09465	COG2801	Transposase and inactivated derivatives
DAES_RS09470	COG2963	transposase activity
DAES_RS09475	COG1696	Membrane protein involved in D-alanine export
DAES_RS09495	COG1215	transferase activity, transferring glycosyl groups
DAES_RS09510	COG1918	ferrous iron import across plasma membrane
DAES_RS09510	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DAES_RS09515	COG1918	ferrous iron import across plasma membrane
DAES_RS09530	COG0735	belongs to the Fur family
DAES_RS09540	COG3864	Putative metallopeptidase domain
DAES_RS09575	COG1760	l-serine dehydratase
DAES_RS09585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DAES_RS09590	COG0765	amino acid transport
DAES_RS09610	COG0473	3-isopropylmalate dehydrogenase activity
DAES_RS09615	COG0066	3-isopropylmalate dehydratase activity
DAES_RS09620	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DAES_RS09625	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DAES_RS09630	COG1183	phosphatidylcholine synthase activity
DAES_RS09635	COG0688	phosphatidylethanolamine metabolic process
DAES_RS09690	COG0588	phosphoglycerate mutase activity
DAES_RS09700	COG0463	Glycosyl transferase, family 2
DAES_RS09700	COG1216	Glycosyl transferase, family 2
DAES_RS09725	COG0521	Mo-molybdopterin cofactor biosynthetic process
DAES_RS09790	COG2801	Transposase and inactivated derivatives
DAES_RS09795	COG2963	transposase activity
DAES_RS09810	COG1342	Belongs to the UPF0251 family
DAES_RS09860	COG0493	'glutamate synthase
DAES_RS09880	COG1959	2 iron, 2 sulfur cluster binding
DAES_RS09890	COG0628	permease
DAES_RS09900	COG0765	amino acid transport
DAES_RS09945	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DAES_RS09950	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DAES_RS09955	COG3959	Transketolase, thiamine diphosphate binding domain
DAES_RS09960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DAES_RS09965	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DAES_RS09975	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DAES_RS09975	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DAES_RS09990	COG1215	transferase activity, transferring glycosyl groups
DAES_RS10005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DAES_RS10010	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DAES_RS10015	COG2089	acid synthase
DAES_RS10025	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DAES_RS10030	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DAES_RS10040	COG1028	Short-chain dehydrogenase reductase Sdr
DAES_RS10045	COG0107	imidazoleglycerol-phosphate synthase activity
DAES_RS10050	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DAES_RS10070	COG4251	negative regulation of phosphorylation
DAES_RS10075	COG0784	Response regulator, receiver
DAES_RS10080	COG4251	negative regulation of phosphorylation
DAES_RS10085	COG5002	protein histidine kinase activity
DAES_RS10105	COG1918	ferrous iron import across plasma membrane
DAES_RS10105	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DAES_RS10115	COG0138	bifunctional purine biosynthesis protein purh
DAES_RS10125	COG1815	bacterial-type flagellum-dependent cell motility
DAES_RS10135	COG1677	Flagellar hook-basal body complex protein FliE
DAES_RS10145	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DAES_RS10155	COG1157	protein secretion by the type III secretion system
DAES_RS10160	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DAES_RS10170	COG0789	Transcriptional regulator
DAES_RS10175	COG0072	phenylalanine-tRNA ligase activity
DAES_RS10175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DAES_RS10190	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DAES_RS10195	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DAES_RS10200	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DAES_RS10235	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
DAES_RS10250	COG1335	isochorismatase
DAES_RS10255	COG1032	radical SAM domain protein
DAES_RS10260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DAES_RS10260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DAES_RS10275	COG1830	Aldolase
DAES_RS10305	COG0859	PFAM glycosyl transferase family 9
DAES_RS10345	COG0601	transmembrane transport
DAES_RS10350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DAES_RS10355	COG0444	Belongs to the ABC transporter superfamily
DAES_RS10360	COG4608	Belongs to the ABC transporter superfamily
DAES_RS10365	COG2963	transposase activity
DAES_RS10370	COG2801	Transposase and inactivated derivatives
DAES_RS10375	COG0745	RESPONSE REGULATOR receiver
DAES_RS10380	COG0446	pyridine nucleotide-disulphide oxidoreductase
DAES_RS10385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DAES_RS10405	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DAES_RS10410	COG1053	succinate dehydrogenase
DAES_RS10420	COG0612	Peptidase, M16
DAES_RS10430	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DAES_RS10435	COG0569	domain protein
DAES_RS10450	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DAES_RS10480	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DAES_RS10485	COG0439	Biotin carboxylase
DAES_RS10500	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DAES_RS10520	COG1013	pyruvate-flavodoxin oxidoreductase activity
DAES_RS10525	COG0674	pyruvate-flavodoxin oxidoreductase activity
DAES_RS10525	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DAES_RS10540	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DAES_RS10545	COG0765	amino acid transport
DAES_RS10550	COG0765	amino acid transport
DAES_RS10555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DAES_RS10585	COG0402	S-adenosylhomocysteine deaminase activity
DAES_RS10590	COG5557	Pfam Polysulphide reductase, NrfD
DAES_RS10595	COG0437	4 iron, 4 sulfur cluster binding
DAES_RS10600	COG0243	molybdopterin cofactor binding
DAES_RS10615	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
DAES_RS10625	COG3956	TIGRFAM MazG family protein
DAES_RS10635	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DAES_RS10635	COG3608	succinylglutamate desuccinylase aspartoacylase
DAES_RS10640	COG2068	MobA-Related Protein
DAES_RS10670	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DAES_RS10675	COG0513	Belongs to the DEAD box helicase family
DAES_RS10685	COG0730	response to heat
DAES_RS10695	COG1160	GTP binding
DAES_RS10700	COG0840	transmembrane signaling receptor activity
DAES_RS10705	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DAES_RS10710	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DAES_RS10730	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DAES_RS10745	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
DAES_RS10750	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DAES_RS10760	COG4786	Flagellar basal body rod
DAES_RS10760	COG1256	bacterial-type flagellum assembly
DAES_RS10760	COG4786	Flagellar basal body rod
DAES_RS10760	COG1256	bacterial-type flagellum assembly
DAES_RS10775	COG1706	bacterial-type flagellum-dependent cell motility
DAES_RS10795	COG4786	Flagellar basal body rod
DAES_RS10805	COG0779	Required for maturation of 30S ribosomal subunits
DAES_RS10810	COG0195	Participates in both transcription termination and antitermination
DAES_RS10820	COG3266	domain, Protein
DAES_RS10820	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DAES_RS10820	COG3266	domain, Protein
DAES_RS10820	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DAES_RS10830	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DAES_RS10840	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DAES_RS10845	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DAES_RS10850	COG1185	polyribonucleotide nucleotidyltransferase activity
DAES_RS10855	COG1355	regulation of microtubule-based process
DAES_RS10875	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
DAES_RS10890	COG1469	GTP cyclohydrolase I activity
DAES_RS10895	COG0864	Transcriptional regulator
DAES_RS10905	COG0509	glycine decarboxylation via glycine cleavage system
DAES_RS10910	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DAES_RS10915	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DAES_RS10920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DAES_RS10925	COG1028	Short-chain dehydrogenase reductase Sdr
DAES_RS10945	COG3681	Belongs to the UPF0597 family
DAES_RS10970	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DAES_RS11000	COG0052	Belongs to the universal ribosomal protein uS2 family
DAES_RS11015	COG0233	cytoplasmic translational termination
DAES_RS11020	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DAES_RS11025	COG4589	Belongs to the CDS family
DAES_RS11030	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DAES_RS11035	COG0750	zinc metalloprotease
DAES_RS11040	COG1214	PFAM Peptidase M22, glycoprotease
DAES_RS11045	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DAES_RS11050	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
DAES_RS11080	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DAES_RS11085	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DAES_RS11095	COG0438	transferase activity, transferring glycosyl groups
DAES_RS11120	COG0535	radical SAM domain protein
DAES_RS11125	COG0113	porphobilinogen synthase activity
DAES_RS11130	COG0535	radical SAM domain protein
DAES_RS11135	COG1522	sequence-specific DNA binding
DAES_RS11145	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DAES_RS11150	COG0488	(ABC) transporter
DAES_RS11160	COG1012	belongs to the aldehyde dehydrogenase family
DAES_RS11165	COG1522	sequence-specific DNA binding
DAES_RS11170	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DAES_RS11175	COG1127	ABC transporter
DAES_RS11190	COG3028	Belongs to the UPF0307 family
DAES_RS11200	COG0697	spore germination
DAES_RS11205	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DAES_RS11215	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DAES_RS11220	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DAES_RS11230	COG0583	DNA-binding transcription factor activity
DAES_RS11235	COG0203	ribosomal protein L17
DAES_RS11240	COG0202	RNA polymerase activity
DAES_RS11245	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DAES_RS11250	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DAES_RS11255	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DAES_RS11270	COG0200	Binds to the 23S rRNA
DAES_RS11275	COG1841	ribosomal large subunit assembly
DAES_RS11280	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DAES_RS11290	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DAES_RS11295	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DAES_RS11300	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DAES_RS11305	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DAES_RS11310	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DAES_RS11315	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DAES_RS11320	COG0255	Belongs to the universal ribosomal protein uL29 family
DAES_RS11325	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DAES_RS11330	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DAES_RS11335	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DAES_RS11340	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DAES_RS11345	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DAES_RS11350	COG0089	rRNA binding
DAES_RS11355	COG0088	Forms part of the polypeptide exit tunnel
DAES_RS11360	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DAES_RS11365	COG0051	transcription antitermination factor activity, RNA binding
DAES_RS11380	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DAES_RS11390	COG0085	RNA polymerase activity
DAES_RS11395	COG0222	ribosome binding
DAES_RS11400	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DAES_RS11405	COG0081	regulation of translation
DAES_RS11410	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DAES_RS11415	COG0250	Participates in transcription elongation, termination and antitermination
DAES_RS11420	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DAES_RS11435	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DAES_RS11460	COG3116	cell division
DAES_RS11460	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DAES_RS11465	COG0784	Response regulator, receiver
DAES_RS11465	COG0835	chemotaxis
DAES_RS11475	COG0409	Hydrogenase expression formation protein
DAES_RS11495	COG1181	Belongs to the D-alanine--D-alanine ligase family
DAES_RS11510	COG0505	Belongs to the CarA family
DAES_RS11520	COG1053	succinate dehydrogenase
DAES_RS11530	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DAES_RS11535	COG0494	nUDIX hydrolase
DAES_RS11540	COG0009	L-threonylcarbamoyladenylate synthase
DAES_RS11545	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DAES_RS11550	COG2204	response regulator
DAES_RS11560	COG2198	Histidine kinase
DAES_RS11560	COG0643	Histidine kinase
DAES_RS11565	COG4822	anaerobic cobalamin biosynthetic process
DAES_RS11570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DAES_RS11575	COG1120	ATPase activity
DAES_RS11590	COG4822	anaerobic cobalamin biosynthetic process
DAES_RS11595	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DAES_RS11625	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DAES_RS11630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DAES_RS11655	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DAES_RS11670	COG0284	orotidine-5'-phosphate decarboxylase activity
DAES_RS11675	COG0194	GDP metabolic process
DAES_RS11680	COG2052	Domain of unknown function (DUF370)
DAES_RS11685	COG1561	YicC-like family, N-terminal region
DAES_RS11695	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DAES_RS11710	COG0482	sulfurtransferase activity
DAES_RS11715	COG0371	Dehydrogenase
DAES_RS11725	COG0154	amidase activity
DAES_RS11740	COG0443	Heat shock 70 kDa protein
DAES_RS11745	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DAES_RS11760	COG0429	hydrolase of the alpha beta-hydrolase fold
DAES_RS11770	COG0542	response to heat
DAES_RS11785	COG2823	Periplasmic or secreted lipoprotein
DAES_RS11790	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
DAES_RS11805	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DAES_RS11810	COG2233	PERMEase
DAES_RS11815	COG0463	Glycosyl transferase, family 2
DAES_RS11820	COG0668	transmembrane transport
DAES_RS11825	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DAES_RS11860	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DAES_RS11865	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DAES_RS11900	COG1216	Glycosyl transferase, family 2
DAES_RS11915	COG1278	Cold shock
DAES_RS11920	COG1119	ATPase activity
DAES_RS11925	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
DAES_RS11930	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
DAES_RS11935	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DAES_RS11945	COG0442	prolyl-tRNA aminoacylation
DAES_RS11950	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DAES_RS11975	COG3260	NADH ubiquinone oxidoreductase 20
DAES_RS11985	COG2111	Na H antiporter
DAES_RS11985	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DAES_RS11990	COG0175	sulfate reduction
DAES_RS12005	COG2801	Transposase and inactivated derivatives
DAES_RS12040	COG3778	Protein conserved in bacteria
DAES_RS12045	COG3299	homolog of phage Mu protein gp47
DAES_RS12050	COG4381	Mu-like prophage protein gp46
DAES_RS12055	COG4384	Bacteriophage Mu Gp45 protein
DAES_RS12065	COG4228	DNA circulation
DAES_RS12080	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
DAES_RS12090	COG4386	tail sheath protein
DAES_RS12120	COG4397	Mu-like prophage major head subunit gpT
DAES_RS12140	COG4383	Mu-like prophage protein gp29
DAES_RS12145	COG4373	Mu-like prophage FluMu protein gp28
DAES_RS12235	COG3409	Peptidoglycan-binding domain 1 protein
DAES_RS12235	COG3267	Type II secretory pathway component ExeA
DAES_RS12300	COG0277	FAD linked oxidase domain protein
DAES_RS12305	COG3852	Histidine kinase
DAES_RS12315	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DAES_RS12320	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DAES_RS12330	COG1216	Glycosyl transferase, family 2
DAES_RS12335	COG0037	tRNA processing
DAES_RS12345	COG2204	response regulator
DAES_RS12350	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DAES_RS12360	COG2801	Transposase and inactivated derivatives
DAES_RS12365	COG2963	transposase activity
DAES_RS12370	COG3676	manually curated
DAES_RS12380	COG0131	Imidazoleglycerol-phosphate dehydratase
DAES_RS12390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DAES_RS12395	COG0519	Catalyzes the synthesis of GMP from XMP
DAES_RS12400	COG0516	GMP reductase activity
DAES_RS12400	COG0517	IMP dehydrogenase activity
DAES_RS12420	COG0559	Belongs to the binding-protein-dependent transport system permease family
DAES_RS12435	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DAES_RS12445	COG1131	(ABC) transporter
DAES_RS12450	COG1138	Cytochrome C-type biogenesis protein
DAES_RS12455	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DAES_RS12460	COG1253	flavin adenine dinucleotide binding
DAES_RS12470	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DAES_RS12475	COG1994	Peptidase M50
DAES_RS12480	COG0180	Tryptophanyl-tRNA synthetase
DAES_RS12485	COG1047	Peptidyl-prolyl cis-trans
DAES_RS12490	COG0436	Aminotransferase
DAES_RS12495	COG2853	Lipoprotein
DAES_RS12505	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DAES_RS12505	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DAES_RS12520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DAES_RS12525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DAES_RS12560	COG0730	response to heat
DAES_RS12565	COG1304	FMN binding
DAES_RS12570	COG2186	Transcriptional regulator
DAES_RS12580	COG1408	metallophosphoesterase
DAES_RS12590	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DAES_RS12590	COG1328	CTP reductase activity
DAES_RS12635	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DAES_RS12640	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DAES_RS12665	COG1254	Belongs to the acylphosphatase family
DAES_RS12670	COG5002	protein histidine kinase activity
DAES_RS12680	COG0835	chemotaxis
DAES_RS12680	COG0784	Response regulator, receiver
DAES_RS12695	COG0745	RESPONSE REGULATOR receiver
DAES_RS12700	COG5002	protein histidine kinase activity
DAES_RS12715	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DAES_RS12735	COG2963	transposase activity
DAES_RS12740	COG2801	Transposase and inactivated derivatives
DAES_RS12795	COG0572	uridine kinase
DAES_RS12800	COG1494	fructose-1,6-bisphosphatase
DAES_RS12810	COG2204	response regulator
DAES_RS12820	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DAES_RS12825	COG0191	fructose-bisphosphate aldolase activity
DAES_RS12830	COG0469	pyruvate kinase activity
DAES_RS12835	COG0126	phosphoglycerate kinase activity
DAES_RS12840	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DAES_RS12845	COG0644	oxidoreductase
DAES_RS12850	COG2801	Transposase and inactivated derivatives
DAES_RS12855	COG2963	transposase activity
DAES_RS12865	COG2801	Transposase and inactivated derivatives
DAES_RS12885	COG3210	domain, Protein
DAES_RS12925	COG1847	R3H domain protein
DAES_RS12930	COG0706	membrane insertase activity
DAES_RS12935	COG0594	ribonuclease P activity
DAES_RS12950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DAES_RS12970	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
DAES_RS12975	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
DAES_RS12985	COG0737	Belongs to the 5'-nucleotidase family
DAES_RS12995	COG3123	guanosine phosphorylase activity
DAES_RS13040	COG1945	arginine decarboxylase activity
DAES_RS13060	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DAES_RS13065	COG0459	protein refolding
DAES_RS13070	COG2329	Antibiotic biosynthesis monooxygenase
DAES_RS13080	COG2414	aldehyde ferredoxin oxidoreductase
DAES_RS13095	COG0798	PFAM Bile acid sodium symporter
DAES_RS13120	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DAES_RS13125	COG0217	transcriptional regulatory protein
DAES_RS13130	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DAES_RS13140	COG0632	four-way junction helicase activity
DAES_RS13150	COG1773	rubredoxin
DAES_RS13165	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DAES_RS13185	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DAES_RS13190	COG4372	Transposase
DAES_RS13200	COG3447	MASE1 domain protein
DAES_RS13200	COG5002	protein histidine kinase activity
DAES_RS13200	COG5001	Diguanylate cyclase
DAES_RS13200	COG5002	protein histidine kinase activity
DAES_RS13200	COG5001	Diguanylate cyclase
DAES_RS13200	COG3447	MASE1 domain protein
DAES_RS13205	COG2703	oxygen carrier activity
DAES_RS13235	COG2204	response regulator
DAES_RS13240	COG2204	response regulator
DAES_RS13245	COG2204	response regulator
DAES_RS13250	COG2204	response regulator
DAES_RS13270	COG0247	lactate metabolic process
DAES_RS13315	COG0745	RESPONSE REGULATOR receiver
DAES_RS13330	COG0318	PFAM AMP-dependent synthetase and ligase
DAES_RS13345	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DAES_RS13350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DAES_RS13355	COG2962	Rard protein
DAES_RS13405	COG3072	Adenylate cyclase
DAES_RS13410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DAES_RS13415	COG1121	(ABC) transporter
DAES_RS13425	COG1472	Belongs to the glycosyl hydrolase 3 family
DAES_RS13435	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DAES_RS13440	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DAES_RS13445	COG0538	isocitrate dehydrogenase activity
DAES_RS13470	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DAES_RS13480	COG1129	ABC transporter
DAES_RS13485	COG4603	Belongs to the binding-protein-dependent transport system permease family
DAES_RS13490	COG1079	Belongs to the binding-protein-dependent transport system permease family
DAES_RS13495	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DAES_RS13505	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DAES_RS13515	COG4191	Histidine kinase
DAES_RS13525	COG2204	response regulator
DAES_RS13530	COG2204	response regulator
DAES_RS13545	COG2204	response regulator
DAES_RS13580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DAES_RS13590	COG0438	transferase activity, transferring glycosyl groups
DAES_RS13620	COG1509	lysine 2,3-aminomutase activity
DAES_RS13625	COG1181	Belongs to the D-alanine--D-alanine ligase family
DAES_RS13630	COG1181	Belongs to the D-alanine--D-alanine ligase family
DAES_RS13645	COG0406	alpha-ribazole phosphatase activity
DAES_RS13665	COG4251	negative regulation of phosphorylation
DAES_RS13665	COG5001	Diguanylate cyclase
DAES_RS13665	COG3706	GGDEF domain
DAES_RS13665	COG2203	Gaf domain
DAES_RS13675	COG0557	exoribonuclease II activity
DAES_RS13680	COG1663	tetraacyldisaccharide 4'-kinase activity
DAES_RS13685	COG0670	Belongs to the BI1 family
DAES_RS13715	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DAES_RS13720	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DAES_RS13725	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DAES_RS13730	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DAES_RS13745	COG0310	cobalt ion transport
DAES_RS13755	COG1959	2 iron, 2 sulfur cluster binding
DAES_RS13770	COG0724	RNA recognition motif
DAES_RS13780	COG0489	protein tyrosine kinase activity
DAES_RS13790	COG2204	response regulator
DAES_RS13795	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DAES_RS13800	COG0375	protein maturation
DAES_RS13810	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DAES_RS13820	COG0456	acetyltransferase
DAES_RS13825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DAES_RS13830	COG0601	transmembrane transport
DAES_RS13865	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DAES_RS13870	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DAES_RS13895	COG3437	response regulator, receiver
DAES_RS13900	COG0469	pyruvate kinase activity
DAES_RS13905	COG2001	Belongs to the MraZ family
DAES_RS13910	COG0275	rRNA processing
DAES_RS13925	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DAES_RS13930	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DAES_RS13935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DAES_RS13945	COG0772	Belongs to the SEDS family
DAES_RS13950	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DAES_RS13955	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DAES_RS13960	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DAES_RS13980	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DAES_RS13990	COG2801	Transposase and inactivated derivatives
DAES_RS14000	COG3547	Transposase (IS116 IS110 IS902 family)
DAES_RS14010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DAES_RS14015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DAES_RS14025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DAES_RS14035	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DAES_RS14045	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DAES_RS14075	COG0437	4 iron, 4 sulfur cluster binding
DAES_RS14080	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DAES_RS14085	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DAES_RS14090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DAES_RS14100	COG4191	Histidine kinase
DAES_RS14115	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DAES_RS14115	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DAES_RS14120	COG2264	protein methyltransferase activity
DAES_RS14140	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DAES_RS14140	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DAES_RS14145	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DAES_RS14150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DAES_RS14160	COG0725	ABC transporter, periplasmic molybdate-binding protein
DAES_RS14190	COG2003	Belongs to the UPF0758 family
DAES_RS14195	COG1254	Belongs to the acylphosphatase family
DAES_RS14200	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DAES_RS14230	COG0181	hydroxymethylbilane synthase activity
DAES_RS14265	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DAES_RS14270	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DAES_RS14310	COG1022	Amp-dependent synthetase and ligase
DAES_RS14330	COG0590	tRNA wobble adenosine to inosine editing
DAES_RS14345	COG0497	DNA recombination
DAES_RS14350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DAES_RS14405	COG0778	Nitroreductase
DAES_RS14425	COG1040	competence protein
DAES_RS14430	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DAES_RS14435	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DAES_RS14445	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DAES_RS14450	COG2814	Major facilitator Superfamily
DAES_RS14460	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DAES_RS14465	COG2703	oxygen carrier activity
DAES_RS14470	COG0303	'Molybdopterin
DAES_RS14480	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DAES_RS14545	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DAES_RS14550	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DAES_RS14565	COG0686	Belongs to the AlaDH PNT family
DAES_RS14615	COG4964	Belongs to the GSP D family
DAES_RS14635	COG2204	response regulator
DAES_RS14660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DAES_RS14670	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DAES_RS14675	COG0490	domain, Protein
DAES_RS14680	COG0475	glutathione-regulated potassium exporter activity
DAES_RS14700	COG3676	manually curated
DAES_RS14735	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DAES_RS14735	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
DAES_RS14745	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DAES_RS14785	COG0791	NLP P60 protein
DAES_RS14795	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DAES_RS14800	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DAES_RS14830	COG1054	Belongs to the UPF0176 family
DAES_RS14835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DAES_RS14840	COG2770	Histidine kinase
DAES_RS14840	COG2208	phosphoserine phosphatase activity
DAES_RS14865	COG0012	GTP binding
DAES_RS14885	COG0840	transmembrane signaling receptor activity
DAES_RS14900	COG0784	Response regulator, receiver
DAES_RS14900	COG0835	chemotaxis
DAES_RS14905	COG2089	acid synthase
DAES_RS14915	COG0318	PFAM AMP-dependent synthetase and ligase
DAES_RS14965	COG1797	cobyrinic acid a,c-diamide synthase activity
DAES_RS14975	COG2221	Nitrite and sulphite reductase 4Fe-4S
DAES_RS14980	COG2221	Nitrite and sulphite reductase 4Fe-4S
DAES_RS14995	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DAES_RS15000	COG4191	Histidine kinase
DAES_RS15010	COG3547	Transposase (IS116 IS110 IS902 family)
DAES_RS15015	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DAES_RS15030	COG0280	phosphate acetyltransferase
DAES_RS15030	COG0281	malic enzyme
DAES_RS15045	COG2358	TRAP transporter, solute receptor (TAXI family
DAES_RS15055	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DAES_RS15075	COG0101	tRNA pseudouridine synthase activity
DAES_RS15080	COG0697	spore germination
DAES_RS15095	COG0432	Pfam Uncharacterised protein family UPF0047
DAES_RS15115	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DAES_RS15120	COG0708	Exodeoxyribonuclease III
DAES_RS15125	COG2081	HI0933 family
DAES_RS15130	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DAES_RS15135	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DAES_RS15140	COG0589	response to stress
DAES_RS15175	COG2113	Glycine betaine
DAES_RS15180	COG4176	ABC-type proline glycine betaine transport system permease component
DAES_RS15185	COG4175	Glycine betaine
DAES_RS15220	COG2046	Belongs to the sulfate adenylyltransferase family
DAES_RS15235	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DAES_RS15265	COG1749	Flagellar hook protein flgE
DAES_RS15275	COG0571	ribonuclease III activity
DAES_RS15285	COG0857	belongs to the CobB CobQ family
DAES_RS15300	COG0519	Catalyzes the synthesis of GMP from XMP
DAES_RS15300	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DAES_RS15305	COG0616	signal peptide processing
DAES_RS15310	COG0539	negative regulation of cytoplasmic translation
DAES_RS15315	COG0704	Plays a role in the regulation of phosphate uptake
DAES_RS15320	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DAES_RS15345	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DAES_RS15355	COG1683	Conserved Protein
DAES_RS15400	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DAES_RS15410	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DAES_RS15415	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DAES_RS15430	COG0709	Synthesizes selenophosphate from selenide and ATP
DAES_RS15445	COG1607	acyl-coa hydrolase
DAES_RS15450	COG0346	lactoylglutathione lyase activity
DAES_RS15460	COG1489	DNA binding
DAES_RS15485	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DAES_RS15500	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DAES_RS15505	COG3238	Protein conserved in bacteria
DAES_RS15520	COG3547	Transposase (IS116 IS110 IS902 family)
DAES_RS15540	COG2226	methyltransferase
DAES_RS15550	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DAES_RS15555	COG1692	metallophosphoesterase
DAES_RS15575	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DAES_RS15580	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DAES_RS15585	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DAES_RS15590	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DAES_RS15595	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DAES_RS15600	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DAES_RS15620	COG0772	Belongs to the SEDS family
DAES_RS15625	COG0768	penicillin binding
DAES_RS15640	COG1077	Cell shape determining protein MreB Mrl
DAES_RS15655	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DAES_RS15660	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DAES_RS15675	COG5336	function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex
DAES_RS15700	COG1410	methionine synthase
DAES_RS15700	COG0646	methionine synthase
DAES_RS15725	COG0698	ribose 5-phosphate isomerase
DAES_RS15735	COG1494	fructose-1,6-bisphosphatase
DAES_RS15765	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DAES_RS15765	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DAES_RS15770	COG2217	Heavy metal translocating P-type atpase
DAES_RS15775	COG0529	Catalyzes the synthesis of activated sulfate
DAES_RS15785	COG1111	helicase
DAES_RS15785	COG1205	dead DEAH box helicase
DAES_RS15810	COG2204	response regulator
DAES_RS15815	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DAES_RS15825	COG2015	COG2015, Alkyl sulfatase and related hydrolases
DAES_RS15845	COG0776	regulation of translation
DAES_RS15850	COG0537	adenosine 5'-monophosphoramidase activity
DAES_RS15860	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DAES_RS15870	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DAES_RS15875	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DAES_RS15890	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DAES_RS15895	COG1132	(ABC) transporter
DAES_RS15905	COG0860	N-Acetylmuramoyl-L-alanine amidase
DAES_RS15910	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DAES_RS15925	COG0243	molybdopterin cofactor binding
DAES_RS15930	COG0437	4 iron, 4 sulfur cluster binding
DAES_RS15960	COG1937	Protein conserved in bacteria
DAES_RS15975	COG1404	Belongs to the peptidase S8 family
DAES_RS15980	COG0826	peptidase U32
DAES_RS15985	COG0071	Belongs to the small heat shock protein (HSP20) family
DAES_RS15995	COG2835	tetraacyldisaccharide 4'-kinase activity
DAES_RS16000	COG0613	PHP domain protein
DAES_RS16005	COG0617	tRNA 3'-terminal CCA addition
DAES_RS16010	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DAES_RS16015	COG0540	Belongs to the ATCase OTCase family
DAES_RS16020	COG0402	S-adenosylhomocysteine deaminase activity
DAES_RS16030	COG2608	mercury ion transmembrane transporter activity
DAES_RS16035	COG2197	response regulator
DAES_RS16050	COG0517	IMP dehydrogenase activity
DAES_RS16055	COG0745	RESPONSE REGULATOR receiver
DAES_RS16060	COG5002	protein histidine kinase activity
DAES_RS16060	COG2205	protein histidine kinase activity
DAES_RS16060	COG0784	Response regulator, receiver
DAES_RS16065	COG3676	manually curated
DAES_RS16100	COG3547	Transposase (IS116 IS110 IS902 family)
DAES_RS16105	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DAES_RS16130	COG2801	Transposase and inactivated derivatives
DAES_RS16135	COG2963	transposase activity
DAES_RS16150	COG3676	manually curated
DAES_RS16170	COG2172	sigma factor antagonist activity
DAES_RS16210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DAES_RS16215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DAES_RS16265	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DAES_RS16275	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DAES_RS16280	COG0534	Mate efflux family protein
DAES_RS16310	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
DAES_RS16315	COG3005	denitrification pathway
DAES_RS16320	COG1309	transcriptional regulator
DAES_RS16340	COG2373	Large extracellular alpha-helical protein
DAES_RS16345	COG4953	penicillin-binding protein 1C
DAES_RS16355	COG0297	glycogen (starch) synthase activity
DAES_RS16375	COG1132	(ABC) transporter
DAES_RS16395	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DAES_RS16410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DAES_RS16420	COG5433	transposase activity
DAES_RS16425	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DAES_RS16425	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DAES_RS16440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DAES_RS16445	COG0450	alkyl hydroperoxide reductase
DAES_RS16460	COG0589	response to stress
DAES_RS16465	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DAES_RS16485	COG3264	Mechanosensitive ion channel
DAES_RS16485	COG1196	nuclear chromosome segregation
DAES_RS16490	COG0546	phosphoglycolate phosphatase activity
DAES_RS16495	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DAES_RS16505	COG0724	RNA recognition motif
DAES_RS16510	COG1280	lysine exporter protein (LysE YggA)
DAES_RS16515	COG3676	manually curated
DAES_RS16520	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DAES_RS16525	COG0606	chelatase, subunit chli
DAES_RS16545	COG0583	DNA-binding transcription factor activity
DAES_RS16565	COG0367	asparagine synthase
DAES_RS16595	COG0438	transferase activity, transferring glycosyl groups
DAES_RS16610	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DAES_RS16615	COG0187	DNA topoisomerase II activity
DAES_RS16625	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DAES_RS16635	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DAES_RS16640	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DAES_RS16645	COG0512	Glutamine amidotransferase of anthranilate synthase
DAES_RS16650	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DAES_RS16655	COG0151	Belongs to the GarS family
DAES_RS16675	COG3676	manually curated
DAES_RS16685	COG2801	Transposase and inactivated derivatives
DAES_RS16700	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DAES_RS16700	COG0674	pyruvate-flavodoxin oxidoreductase activity
DAES_RS16725	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DAES_RS16760	COG2205	protein histidine kinase activity
DAES_RS16760	COG4999	Histidine kinase
DAES_RS16760	COG3850	Histidine kinase
DAES_RS16760	COG3437	response regulator, receiver
DAES_RS16770	COG1215	transferase activity, transferring glycosyl groups
DAES_RS16775	COG1083	cytidylyl-transferase
DAES_RS16780	COG1216	Glycosyl transferase, family 2
DAES_RS16835	COG4977	sequence-specific DNA binding
DAES_RS16845	COG0784	Response regulator, receiver
DAES_RS16845	COG2205	protein histidine kinase activity
DAES_RS16860	COG2770	Histidine kinase
DAES_RS16860	COG2208	phosphoserine phosphatase activity
DAES_RS16865	COG0784	Response regulator, receiver
DAES_RS16865	COG4191	Histidine kinase
DAES_RS16870	COG2226	methyltransferase
DAES_RS16880	COG1132	(ABC) transporter
DAES_RS16905	COG2205	protein histidine kinase activity
DAES_RS16905	COG0784	Response regulator, receiver
DAES_RS16930	COG2801	Transposase and inactivated derivatives
DAES_RS16945	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DAES_RS16965	COG2205	protein histidine kinase activity
DAES_RS16965	COG2198	Histidine kinase
DAES_RS16965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DAES_RS16965	COG0784	Response regulator, receiver
DAES_RS16980	COG0840	transmembrane signaling receptor activity
DAES_RS16995	COG0681	Belongs to the peptidase S26 family
DAES_RS17000	COG0805	protein transport
DAES_RS17005	COG2205	protein histidine kinase activity
DAES_RS17005	COG2202	Pas domain
DAES_RS17040	COG3920	Histidine kinase
DAES_RS17070	COG5002	protein histidine kinase activity
DAES_RS17085	COG2205	protein histidine kinase activity
DAES_RS17085	COG0784	Response regulator, receiver
DAES_RS17115	COG2202	Pas domain
DAES_RS17115	COG2205	protein histidine kinase activity