locus-tag	class	description
DND132_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DND132_RS00010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DND132_RS00025	COG0750	zinc metalloprotease
DND132_RS00030	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DND132_RS00035	COG4589	Belongs to the CDS family
DND132_RS00045	COG0233	cytoplasmic translational termination
DND132_RS00060	COG0052	Belongs to the universal ribosomal protein uS2 family
DND132_RS00075	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DND132_RS00100	COG3681	Belongs to the UPF0597 family
DND132_RS00110	COG0038	chloride channel
DND132_RS00135	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DND132_RS00140	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DND132_RS00145	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DND132_RS00150	COG0509	glycine decarboxylation via glycine cleavage system
DND132_RS00160	COG0864	Transcriptional regulator
DND132_RS00165	COG1469	GTP cyclohydrolase I activity
DND132_RS00170	COG1558	bacterial-type flagellum-dependent cell motility
DND132_RS00175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DND132_RS00190	COG1355	regulation of microtubule-based process
DND132_RS00205	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DND132_RS00210	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DND132_RS00220	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DND132_RS00230	COG3266	domain, Protein
DND132_RS00230	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DND132_RS00230	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DND132_RS00230	COG3266	domain, Protein
DND132_RS00240	COG0195	Participates in both transcription termination and antitermination
DND132_RS00255	COG4786	Flagellar basal body rod
DND132_RS00270	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DND132_RS00275	COG1706	bacterial-type flagellum-dependent cell motility
DND132_RS00290	COG4786	Flagellar basal body rod
DND132_RS00290	COG1256	bacterial-type flagellum assembly
DND132_RS00290	COG4786	Flagellar basal body rod
DND132_RS00290	COG1256	bacterial-type flagellum assembly
DND132_RS00300	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DND132_RS00305	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
DND132_RS00320	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DND132_RS00330	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
DND132_RS00340	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DND132_RS00345	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DND132_RS00350	COG1160	GTP binding
DND132_RS00360	COG0842	Transport permease protein
DND132_RS00365	COG0842	Transport permease protein
DND132_RS00370	COG1131	(ABC) transporter
DND132_RS00395	COG3454	Phosphonate metabolism
DND132_RS00405	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DND132_RS00410	COG3639	organic phosphonate transmembrane transporter activity
DND132_RS00420	COG0529	Catalyzes the synthesis of activated sulfate
DND132_RS00445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DND132_RS00450	COG0577	efflux transmembrane transporter activity
DND132_RS00450	COG1136	(ABC) transporter
DND132_RS00465	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DND132_RS00480	COG2204	response regulator
DND132_RS00505	COG1175	transmembrane transport
DND132_RS00515	COG3842	ATPase activity
DND132_RS00520	COG3842	ATPase activity
DND132_RS00525	COG0535	radical SAM domain protein
DND132_RS00530	COG0243	molybdopterin cofactor binding
DND132_RS00535	COG3384	dioxygenase
DND132_RS00555	COG3956	TIGRFAM MazG family protein
DND132_RS00565	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
DND132_RS00570	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
DND132_RS00570	COG0662	Cupin 2, conserved barrel domain protein
DND132_RS00580	COG0243	molybdopterin cofactor binding
DND132_RS00585	COG0437	4 iron, 4 sulfur cluster binding
DND132_RS00590	COG5557	Pfam Polysulphide reductase, NrfD
DND132_RS00595	COG2358	TRAP transporter, solute receptor (TAXI family
DND132_RS00600	COG1126	abc transporter atp-binding protein
DND132_RS00605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DND132_RS00610	COG0765	amino acid transport
DND132_RS00615	COG0765	amino acid transport
DND132_RS00630	COG0674	pyruvate-flavodoxin oxidoreductase activity
DND132_RS00630	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DND132_RS00635	COG1013	pyruvate-flavodoxin oxidoreductase activity
DND132_RS00655	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DND132_RS00660	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DND132_RS00675	COG0439	Biotin carboxylase
DND132_RS00680	COG0825	malonyl-CoA metabolic process
DND132_RS00700	COG1396	sequence-specific DNA binding
DND132_RS00730	COG2226	methyltransferase
DND132_RS00740	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DND132_RS00750	COG3608	succinylglutamate desuccinylase aspartoacylase
DND132_RS00750	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DND132_RS00755	COG2068	MobA-Related Protein
DND132_RS00770	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DND132_RS00795	COG0765	amino acid transport
DND132_RS00800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DND132_RS00810	COG1760	l-serine dehydratase
DND132_RS00815	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DND132_RS00820	COG0745	RESPONSE REGULATOR receiver
DND132_RS00835	COG2204	response regulator
DND132_RS00860	COG2204	response regulator
DND132_RS00880	COG4658	electron transport chain
DND132_RS00890	COG4660	Part of a membrane complex involved in electron transport
DND132_RS00895	COG4657	Part of a membrane complex involved in electron transport
DND132_RS00905	COG1166	arginine decarboxylase activity
DND132_RS00910	COG2204	response regulator
DND132_RS00920	COG2855	membrane
DND132_RS00935	COG0642	Histidine kinase
DND132_RS00955	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DND132_RS00980	COG1185	polyribonucleotide nucleotidyltransferase activity
DND132_RS00990	COG0305	Participates in initiation and elongation during chromosome replication
DND132_RS01010	COG0438	transferase activity, transferring glycosyl groups
DND132_RS01055	COG0463	Glycosyl transferase, family 2
DND132_RS01065	COG0438	transferase activity, transferring glycosyl groups
DND132_RS01075	COG2201	protein-glutamate methylesterase activity
DND132_RS01085	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DND132_RS01090	COG0745	RESPONSE REGULATOR receiver
DND132_RS01095	COG2198	Histidine kinase
DND132_RS01095	COG0643	Histidine kinase
DND132_RS01095	COG0784	Response regulator, receiver
DND132_RS01095	COG0643	Histidine kinase
DND132_RS01095	COG2198	Histidine kinase
DND132_RS01095	COG0784	Response regulator, receiver
DND132_RS01110	COG0758	DNA mediated transformation
DND132_RS01115	COG2119	membrane
DND132_RS01140	COG4974	Belongs to the 'phage' integrase family
DND132_RS01150	COG2070	2-Nitropropane dioxygenase
DND132_RS01155	COG0579	oxidoreductase
DND132_RS01170	COG1074	ATP-dependent DNA helicase activity
DND132_RS01185	COG0564	pseudouridine synthase activity
DND132_RS01195	COG0539	negative regulation of cytoplasmic translation
DND132_RS01200	COG0552	protein localization to endoplasmic reticulum
DND132_RS01205	COG0017	Asparaginyl-tRNA synthetase
DND132_RS01265	COG0352	thiamine-phosphate diphosphorylase activity
DND132_RS01265	COG0351	phosphomethylpyrimidine kinase
DND132_RS01275	COG0544	peptidyl-prolyl cis-trans isomerase activity
DND132_RS01280	COG0740	serine-type endopeptidase activity
DND132_RS01290	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DND132_RS01310	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DND132_RS01320	COG0489	protein tyrosine kinase activity
DND132_RS01325	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DND132_RS01355	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DND132_RS01360	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DND132_RS01365	COG3118	belongs to the thioredoxin family
DND132_RS01370	COG0492	ferredoxin-NADP+ reductase activity
DND132_RS01375	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DND132_RS01385	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DND132_RS01400	COG0643	Histidine kinase
DND132_RS01400	COG2198	Histidine kinase
DND132_RS01405	COG2201	protein-glutamate methylesterase activity
DND132_RS01410	COG1993	acr, cog1993
DND132_RS01415	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DND132_RS01425	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DND132_RS01430	COG0542	response to heat
DND132_RS01435	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DND132_RS01445	COG0556	nucleotide-excision repair
DND132_RS01455	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DND132_RS01460	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DND132_RS01465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DND132_RS01470	COG0534	Mate efflux family protein
DND132_RS01505	COG0799	negative regulation of ribosome biogenesis
DND132_RS01510	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DND132_RS01540	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DND132_RS01545	COG0742	ribosomal rna small subunit methyltransferase
DND132_RS01555	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DND132_RS01575	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DND132_RS01580	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DND132_RS01610	COG1872	DUF167
DND132_RS01620	COG0028	Belongs to the TPP enzyme family
DND132_RS01625	COG0440	acetolactate synthase activity
DND132_RS01630	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DND132_RS01635	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
DND132_RS01645	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
DND132_RS01655	COG0243	molybdopterin cofactor binding
DND132_RS01655	COG3383	formate dehydrogenase (NAD+) activity
DND132_RS01660	COG0243	molybdopterin cofactor binding
DND132_RS01660	COG3383	formate dehydrogenase (NAD+) activity
DND132_RS01665	COG0437	4 iron, 4 sulfur cluster binding
DND132_RS01675	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DND132_RS01685	COG2267	carboxylic ester hydrolase activity
DND132_RS01695	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DND132_RS01700	COG0210	DNA helicase
DND132_RS01720	COG1122	ATPase activity
DND132_RS01725	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DND132_RS01735	COG4608	Belongs to the ABC transporter superfamily
DND132_RS01740	COG0444	Belongs to the ABC transporter superfamily
DND132_RS01745	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DND132_RS01750	COG2873	o-acetylhomoserine
DND132_RS01770	COG0765	amino acid transport
DND132_RS01775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DND132_RS01780	COG0765	amino acid transport
DND132_RS01785	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DND132_RS01795	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DND132_RS01805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DND132_RS01810	COG0527	aspartate kinase activity
DND132_RS01815	COG0802	atpase or kinase
DND132_RS01820	COG0516	GMP reductase activity
DND132_RS01820	COG0517	IMP dehydrogenase activity
DND132_RS01825	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DND132_RS01825	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DND132_RS01830	COG0736	holo-[acyl-carrier-protein] synthase activity
DND132_RS01835	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DND132_RS01850	COG0835	chemotaxis
DND132_RS01865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DND132_RS01875	COG1381	Involved in DNA repair and RecF pathway recombination
DND132_RS01880	COG0752	glycyl-tRNA synthetase alpha subunit
DND132_RS01885	COG0751	glycine-tRNA ligase activity
DND132_RS01890	COG0268	Binds directly to 16S ribosomal RNA
DND132_RS01920	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DND132_RS01925	COG0569	domain protein
DND132_RS01940	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DND132_RS01950	COG2239	Acts as a magnesium transporter
DND132_RS01980	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DND132_RS01985	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DND132_RS01995	COG1045	serine acetyltransferase
DND132_RS02005	COG1104	cysteine desulfurase activity
DND132_RS02035	COG1067	ATP-dependent peptidase activity
DND132_RS02040	COG0028	Belongs to the TPP enzyme family
DND132_RS02045	COG0440	acetolactate synthase activity
DND132_RS02065	COG0835	chemotaxis
DND132_RS02075	COG0396	ATPase activity
DND132_RS02080	COG0719	Fe-S assembly protein
DND132_RS02085	COG1309	transcriptional regulator
DND132_RS02095	COG0438	transferase activity, transferring glycosyl groups
DND132_RS02115	COG0617	tRNA 3'-terminal CCA addition
DND132_RS02125	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DND132_RS02150	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DND132_RS02170	COG0243	molybdopterin cofactor binding
DND132_RS02175	COG0437	4 iron, 4 sulfur cluster binding
DND132_RS02205	COG1968	undecaprenyl-diphosphatase activity
DND132_RS02225	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DND132_RS02230	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DND132_RS02235	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DND132_RS02240	COG1674	ftsk spoiiie
DND132_RS02245	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DND132_RS02250	COG1187	pseudouridine synthase activity
DND132_RS02265	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DND132_RS02280	COG0483	inositol monophosphate 1-phosphatase activity
DND132_RS02290	COG0456	acetyltransferase
DND132_RS02295	COG0126	phosphoglycerate kinase activity
DND132_RS02300	COG0149	triose-phosphate isomerase activity
DND132_RS02305	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DND132_RS02370	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DND132_RS02375	COG0436	Aminotransferase
DND132_RS02380	COG4974	Belongs to the 'phage' integrase family
DND132_RS02385	COG3620	sequence-specific DNA binding
DND132_RS02385	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DND132_RS02385	COG0617	tRNA 3'-terminal CCA addition
DND132_RS02400	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DND132_RS02405	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DND132_RS02415	COG0019	diaminopimelate decarboxylase activity
DND132_RS02420	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DND132_RS02425	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DND132_RS02430	COG4641	Protein conserved in bacteria
DND132_RS02440	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DND132_RS02440	COG1648	precorrin-2 dehydrogenase activity
DND132_RS02450	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DND132_RS02460	COG0037	tRNA processing
DND132_RS02465	COG0563	adenylate kinase activity
DND132_RS02480	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DND132_RS02485	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DND132_RS02490	COG1862	Preprotein translocase
DND132_RS02500	COG0067	glutamate synthase
DND132_RS02505	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DND132_RS02510	COG0493	'glutamate synthase
DND132_RS02510	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DND132_RS02520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DND132_RS02530	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DND132_RS02540	COG2264	protein methyltransferase activity
DND132_RS02555	COG0793	Belongs to the peptidase S41A family
DND132_RS02575	COG4120	Belongs to the binding-protein-dependent transport system permease family
DND132_RS02580	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DND132_RS02585	COG0105	UTP biosynthetic process
DND132_RS02590	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DND132_RS02595	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DND132_RS02605	COG0358	DNA primase activity
DND132_RS02610	COG1193	negative regulation of DNA recombination
DND132_RS02615	COG1610	YqeY-like protein
DND132_RS02620	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DND132_RS02625	COG0776	regulation of translation
DND132_RS02630	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DND132_RS02635	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DND132_RS02640	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DND132_RS02645	COG0402	S-adenosylhomocysteine deaminase activity
DND132_RS02655	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DND132_RS02660	COG0445	tRNA wobble uridine modification
DND132_RS02665	COG4535	Mg2 and Co2 transporter CorC
DND132_RS02675	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DND132_RS02690	COG0776	regulation of translation
DND132_RS02700	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DND132_RS02710	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DND132_RS02715	COG3842	ATPase activity
DND132_RS02720	COG1176	ABC-type spermidine putrescine transport system, permease component I
DND132_RS02725	COG1177	transmembrane transport
DND132_RS02735	COG1227	inorganic diphosphatase activity
DND132_RS02745	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DND132_RS02755	COG1660	Displays ATPase and GTPase activities
DND132_RS02760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DND132_RS02775	COG1137	ATPase activity
DND132_RS02790	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DND132_RS02800	COG0504	CTP synthase activity
DND132_RS02805	COG0047	phosphoribosylformylglycinamidine synthase activity
DND132_RS02835	COG0732	type I restriction modification DNA specificity domain
DND132_RS02845	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
DND132_RS02870	COG3695	enzyme binding
DND132_RS02900	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DND132_RS02905	COG0439	Biotin carboxylase
DND132_RS02910	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DND132_RS02920	COG0488	(ABC) transporter
DND132_RS02925	COG1013	pyruvate-flavodoxin oxidoreductase activity
DND132_RS02930	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DND132_RS02930	COG0674	pyruvate-flavodoxin oxidoreductase activity
DND132_RS02940	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DND132_RS02945	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DND132_RS02950	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DND132_RS02955	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DND132_RS02965	COG0436	Aminotransferase
DND132_RS02975	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
DND132_RS02980	COG0824	Thioesterase
DND132_RS02995	COG2210	Belongs to the sulfur carrier protein TusA family
DND132_RS03005	COG0765	amino acid transport
DND132_RS03010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DND132_RS03015	COG3845	ABC transporter
DND132_RS03020	COG1079	Belongs to the binding-protein-dependent transport system permease family
DND132_RS03025	COG4603	Belongs to the binding-protein-dependent transport system permease family
DND132_RS03035	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DND132_RS03040	COG0837	glucose binding
DND132_RS03045	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DND132_RS03055	COG0424	maF-like protein
DND132_RS03065	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DND132_RS03070	COG1247	-acetyltransferase
DND132_RS03085	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DND132_RS03095	COG0823	Involved in the tonB-independent uptake of proteins
DND132_RS03125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DND132_RS03130	COG0529	Catalyzes the synthesis of activated sulfate
DND132_RS03140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DND132_RS03145	COG1324	tolerance protein
DND132_RS03150	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DND132_RS03155	COG0343	queuine tRNA-ribosyltransferase activity
DND132_RS03160	COG1295	ribonuclease BN
DND132_RS03175	COG3494	Protein of unknown function (DUF1009)
DND132_RS03190	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DND132_RS03200	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DND132_RS03205	COG1136	(ABC) transporter
DND132_RS03215	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DND132_RS03230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DND132_RS03240	COG0011	TIGRFAM Protein of
DND132_RS03245	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DND132_RS03250	COG0352	thiamine-phosphate diphosphorylase activity
DND132_RS03260	COG2205	protein histidine kinase activity
DND132_RS03265	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
DND132_RS03275	COG2943	transferase activity, transferring hexosyl groups
DND132_RS03290	COG1454	alcohol dehydrogenase
DND132_RS03300	COG0006	proline dipeptidase activity
DND132_RS03315	COG0484	heat shock protein binding
DND132_RS03320	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DND132_RS03325	COG0107	imidazoleglycerol-phosphate synthase activity
DND132_RS03330	COG0315	cyclic pyranopterin monophosphate synthase activity
DND132_RS03340	COG1758	RNA polymerase activity
DND132_RS03350	COG0037	tRNA processing
DND132_RS03355	COG0739	heme binding
DND132_RS03360	COG1684	flagellar biosynthetic protein fliR
DND132_RS03365	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DND132_RS03370	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DND132_RS03415	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DND132_RS03420	COG2890	protein-(glutamine-N5) methyltransferase activity
DND132_RS03425	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DND132_RS03430	COG3872	metal-dependent enzyme
DND132_RS03435	COG0254	rRNA binding
DND132_RS03440	COG2920	part of a sulfur-relay system
DND132_RS03460	COG0745	RESPONSE REGULATOR receiver
DND132_RS03475	COG0492	ferredoxin-NADP+ reductase activity
DND132_RS03500	COG4658	electron transport chain
DND132_RS03510	COG4660	Part of a membrane complex involved in electron transport
DND132_RS03520	COG4657	Part of a membrane complex involved in electron transport
DND132_RS03545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DND132_RS03545	COG0723	plastoquinol--plastocyanin reductase activity
DND132_RS03560	COG3119	arylsulfatase activity
DND132_RS03565	COG0583	DNA-binding transcription factor activity
DND132_RS03580	COG2414	aldehyde ferredoxin oxidoreductase
DND132_RS03590	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DND132_RS03600	COG2998	abc-type tungstate transport system, permease component
DND132_RS03605	COG4662	Binding-protein-dependent transport system inner membrane component
DND132_RS03620	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DND132_RS03630	COG1091	dTDP-4-dehydrorhamnose reductase activity
DND132_RS03645	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DND132_RS03650	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DND132_RS03660	COG0494	nUDIX hydrolase
DND132_RS03665	COG0488	(ABC) transporter
DND132_RS03670	COG2827	Endonuclease containing a URI domain
DND132_RS03685	COG0473	3-isopropylmalate dehydrogenase activity
DND132_RS03695	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DND132_RS03700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DND132_RS03705	COG1183	phosphatidylcholine synthase activity
DND132_RS03710	COG0688	phosphatidylethanolamine metabolic process
DND132_RS03770	COG0588	phosphoglycerate mutase activity
DND132_RS03805	COG0521	Mo-molybdopterin cofactor biosynthetic process
DND132_RS03815	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DND132_RS03855	COG0531	amino acid
DND132_RS03865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DND132_RS03870	COG4597	amino acid ABC transporter
DND132_RS03875	COG0765	amino acid transport
DND132_RS03880	COG1126	abc transporter atp-binding protein
DND132_RS03890	COG0659	secondary active sulfate transmembrane transporter activity
DND132_RS03895	COG4974	Belongs to the 'phage' integrase family
DND132_RS03905	COG4149	molybdate abc transporter
DND132_RS03915	COG1132	(ABC) transporter
DND132_RS03925	COG0493	'glutamate synthase
DND132_RS03945	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
DND132_RS03950	COG0628	permease
DND132_RS03965	COG0765	amino acid transport
DND132_RS03975	COG2755	lipolytic protein G-D-S-L family
DND132_RS03975	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DND132_RS03985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DND132_RS03990	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DND132_RS03995	COG2089	acid synthase
DND132_RS04000	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DND132_RS04010	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DND132_RS04015	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DND132_RS04020	COG1028	Short-chain dehydrogenase reductase Sdr
DND132_RS04040	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DND132_RS04040	COG1918	ferrous iron import across plasma membrane
DND132_RS04050	COG0251	oxidation-reduction process
DND132_RS04055	COG1830	Aldolase
DND132_RS04065	COG0741	lytic transglycosylase activity
DND132_RS04100	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DND132_RS04120	COG0747	negative chemotaxis
DND132_RS04125	COG0601	transmembrane transport
DND132_RS04130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DND132_RS04135	COG0444	Belongs to the ABC transporter superfamily
DND132_RS04140	COG4608	Belongs to the ABC transporter superfamily
DND132_RS04145	COG0446	pyridine nucleotide-disulphide oxidoreductase
DND132_RS04150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DND132_RS04165	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DND132_RS04175	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DND132_RS04180	COG1053	succinate dehydrogenase
DND132_RS04195	COG1309	transcriptional regulator
DND132_RS04210	COG3647	Membrane
DND132_RS04215	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DND132_RS04220	COG0569	domain protein
DND132_RS04225	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DND132_RS04230	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DND132_RS04235	COG0012	GTP binding
DND132_RS04265	COG1007	ATP synthesis coupled electron transport
DND132_RS04275	COG0651	ATP synthesis coupled electron transport
DND132_RS04285	COG0651	ATP synthesis coupled electron transport
DND132_RS04290	COG0713	ATP synthesis coupled electron transport
DND132_RS04300	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DND132_RS04305	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DND132_RS04310	COG0649	NAD binding
DND132_RS04320	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DND132_RS04325	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DND132_RS04340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DND132_RS04345	COG0438	transferase activity, transferring glycosyl groups
DND132_RS04350	COG0671	phosphoesterase, PA-phosphatase related
DND132_RS04375	COG0667	Aldo Keto reductase
DND132_RS04390	COG0471	metal ion transport
DND132_RS04410	COG1063	alcohol dehydrogenase
DND132_RS04415	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DND132_RS04420	COG0352	thiamine-phosphate diphosphorylase activity
DND132_RS04430	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DND132_RS04435	COG2022	thiamine diphosphate biosynthetic process
DND132_RS04460	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DND132_RS04470	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DND132_RS04475	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DND132_RS04485	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DND132_RS04490	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DND132_RS04495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DND132_RS04500	COG0165	Argininosuccinate lyase
DND132_RS04505	COG0137	argininosuccinate synthase activity
DND132_RS04510	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DND132_RS04520	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DND132_RS04525	COG1702	phosphate starvation-inducible protein PhoH
DND132_RS04550	COG0640	Transcriptional regulator
DND132_RS04560	COG0784	Response regulator, receiver
DND132_RS04560	COG0835	chemotaxis
DND132_RS04595	COG0163	prenyltransferase activity
DND132_RS04600	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DND132_RS04610	COG0322	excinuclease ABC activity
DND132_RS04620	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DND132_RS04625	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DND132_RS04630	COG0360	Binds together with S18 to 16S ribosomal RNA
DND132_RS04635	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DND132_RS04640	COG0359	binds to the 23S rRNA
DND132_RS04645	COG0305	Participates in initiation and elongation during chromosome replication
DND132_RS04650	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DND132_RS04670	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DND132_RS04675	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DND132_RS04695	COG1122	ATPase activity
DND132_RS04715	COG0385	Bile acid
DND132_RS04720	COG5002	protein histidine kinase activity
DND132_RS04720	COG0784	Response regulator, receiver
DND132_RS04720	COG2205	protein histidine kinase activity
DND132_RS04740	COG0167	dihydroorotate dehydrogenase activity
DND132_RS04745	COG0543	2 iron, 2 sulfur cluster binding
DND132_RS04750	COG0826	peptidase U32
DND132_RS04780	COG0517	IMP dehydrogenase activity
DND132_RS04780	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DND132_RS04785	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DND132_RS04790	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DND132_RS04810	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DND132_RS04810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DND132_RS04815	COG1774	PSP1 C-terminal conserved region
DND132_RS04820	COG0784	Response regulator, receiver
DND132_RS04820	COG5002	protein histidine kinase activity
DND132_RS04820	COG2205	protein histidine kinase activity
DND132_RS04825	COG1234	tRNA 3'-trailer cleavage
DND132_RS04840	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DND132_RS04870	COG1362	aminopeptidase activity
DND132_RS04875	COG1921	L-seryl-tRNASec selenium transferase activity
DND132_RS04880	COG0285	dihydrofolate synthase activity
DND132_RS04885	COG0840	transmembrane signaling receptor activity
DND132_RS04975	COG1216	Glycosyl transferase, family 2
DND132_RS04990	COG1408	metallophosphoesterase
DND132_RS04995	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DND132_RS05015	COG0840	transmembrane signaling receptor activity
DND132_RS05025	COG3604	Transcriptional regulator
DND132_RS05050	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DND132_RS05070	COG2204	response regulator
DND132_RS05075	COG0519	Catalyzes the synthesis of GMP from XMP
DND132_RS05085	COG1620	l-lactate permease
DND132_RS05090	COG0277	FAD linked oxidase domain protein
DND132_RS05095	COG0247	lactate metabolic process
DND132_RS05100	COG0857	belongs to the CobB CobQ family
DND132_RS05100	COG0280	phosphate acetyltransferase
DND132_RS05105	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DND132_RS05110	COG1556	Lactate utilization protein
DND132_RS05115	COG1139	Iron-sulfur cluster binding protein
DND132_RS05120	COG0840	transmembrane signaling receptor activity
DND132_RS05125	COG0776	regulation of translation
DND132_RS05145	COG1217	gtp-binding protein TYPA
DND132_RS05150	COG0725	ABC transporter, periplasmic molybdate-binding protein
DND132_RS05155	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DND132_RS05160	COG3842	ATPase activity
DND132_RS05165	COG0697	spore germination
DND132_RS05225	COG1773	rubredoxin
DND132_RS05235	COG0632	four-way junction helicase activity
DND132_RS05245	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DND132_RS05255	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DND132_RS05275	COG3290	protein histidine kinase activity
DND132_RS05275	COG3829	transcription factor binding
DND132_RS05285	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DND132_RS05295	COG3842	ATPase activity
DND132_RS05300	COG1176	ABC-type spermidine putrescine transport system, permease component I
DND132_RS05305	COG1177	transmembrane transport
DND132_RS05310	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DND132_RS05325	COG1012	belongs to the aldehyde dehydrogenase family
DND132_RS05360	COG0745	RESPONSE REGULATOR receiver
DND132_RS05370	COG0318	PFAM AMP-dependent synthetase and ligase
DND132_RS05375	COG1794	racemase activity, acting on amino acids and derivatives
DND132_RS05385	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DND132_RS05390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DND132_RS05395	COG2962	Rard protein
DND132_RS05415	COG1335	isochorismatase
DND132_RS05460	COG2329	Antibiotic biosynthesis monooxygenase
DND132_RS05465	COG1757	Na H antiporter
DND132_RS05470	COG0454	-acetyltransferase
DND132_RS05480	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DND132_RS05490	COG0840	transmembrane signaling receptor activity
DND132_RS05495	COG0138	bifunctional purine biosynthesis protein purh
DND132_RS05500	COG4095	Psort location CytoplasmicMembrane, score
DND132_RS05505	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
DND132_RS05510	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DND132_RS05515	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DND132_RS05540	COG1815	bacterial-type flagellum-dependent cell motility
DND132_RS05550	COG1677	Flagellar hook-basal body complex protein FliE
DND132_RS05560	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DND132_RS05570	COG1157	protein secretion by the type III secretion system
DND132_RS05575	COG2982	Protein involved in outer membrane biogenesis
DND132_RS05580	COG0789	Transcriptional regulator
DND132_RS05590	COG0072	phenylalanine-tRNA ligase activity
DND132_RS05590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DND132_RS05605	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DND132_RS05610	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DND132_RS05615	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DND132_RS05655	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
DND132_RS05670	COG1278	Cold shock
DND132_RS05675	COG0724	RNA recognition motif
DND132_RS05680	COG1119	ATPase activity
DND132_RS05685	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
DND132_RS05690	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
DND132_RS05700	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DND132_RS05705	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DND132_RS05705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DND132_RS05710	COG0840	transmembrane signaling receptor activity
DND132_RS05715	COG0277	FAD linked oxidase domain protein
DND132_RS05730	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DND132_RS05735	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DND132_RS05755	COG0251	oxidation-reduction process
DND132_RS05760	COG0463	Glycosyl transferase, family 2
DND132_RS05760	COG1216	Glycosyl transferase, family 2
DND132_RS05765	COG0037	tRNA processing
DND132_RS05775	COG2204	response regulator
DND132_RS05785	COG1994	Peptidase M50
DND132_RS05790	COG0180	Tryptophanyl-tRNA synthetase
DND132_RS05795	COG1047	Peptidyl-prolyl cis-trans
DND132_RS05800	COG0436	Aminotransferase
DND132_RS05815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DND132_RS05870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DND132_RS05880	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DND132_RS05885	COG0778	Nitroreductase
DND132_RS05890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DND132_RS05900	COG0437	4 iron, 4 sulfur cluster binding
DND132_RS05915	COG0513	Belongs to the DEAD box helicase family
DND132_RS05925	COG3437	response regulator, receiver
DND132_RS05965	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DND132_RS05970	COG2814	Major facilitator Superfamily
DND132_RS05975	COG1566	PFAM secretion protein HlyD family protein
DND132_RS05980	COG1309	transcriptional regulator
DND132_RS05990	COG2204	response regulator
DND132_RS05995	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DND132_RS06005	COG0471	metal ion transport
DND132_RS06005	COG3273	potassium ion transport
DND132_RS06010	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DND132_RS06020	COG1803	Methylglyoxal synthase
DND132_RS06025	COG2193	ferroxidase activity
DND132_RS06030	COG1012	belongs to the aldehyde dehydrogenase family
DND132_RS06040	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DND132_RS06050	COG0438	transferase activity, transferring glycosyl groups
DND132_RS06065	COG2244	polysaccharide biosynthetic process
DND132_RS06070	COG0438	transferase activity, transferring glycosyl groups
DND132_RS06085	COG0438	transferase activity, transferring glycosyl groups
DND132_RS06110	COG2204	response regulator
DND132_RS06135	COG3409	Peptidoglycan-binding domain 1 protein
DND132_RS06135	COG3267	Type II secretory pathway component ExeA
DND132_RS06150	COG1596	polysaccharide export
DND132_RS06155	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DND132_RS06190	COG2226	methyltransferase
DND132_RS06215	COG2204	response regulator
DND132_RS06225	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DND132_RS06235	COG2814	Major facilitator Superfamily
DND132_RS06245	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DND132_RS06245	COG1328	CTP reductase activity
DND132_RS06260	COG1979	alcohol dehydrogenase
DND132_RS06265	COG2207	Transcriptional regulator
DND132_RS06270	COG0583	DNA-binding transcription factor activity
DND132_RS06285	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DND132_RS06325	COG2207	Transcriptional regulator
DND132_RS06345	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DND132_RS06380	COG0251	oxidation-reduction process
DND132_RS06385	COG2271	Major facilitator Superfamily
DND132_RS06395	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DND132_RS06400	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DND132_RS06405	COG3924	membrane
DND132_RS06410	COG4145	pantothenate transmembrane transporter activity
DND132_RS06420	COG2186	Transcriptional regulator
DND132_RS06425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DND132_RS06430	COG0765	amino acid transport
DND132_RS06435	COG0765	amino acid transport
DND132_RS06450	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DND132_RS06455	COG3257	ureidoglycine aminohydrolase activity
DND132_RS06460	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DND132_RS06500	COG1538	Outer membrane efflux protein
DND132_RS06505	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DND132_RS06505	COG2199	diguanylate cyclase activity
DND132_RS06520	COG2274	protein secretion by the type I secretion system
DND132_RS06525	COG3321	synthase
DND132_RS06525	COG0604	alcohol dehydrogenase
DND132_RS06530	COG1032	radical SAM domain protein
DND132_RS06550	COG0535	radical SAM domain protein
DND132_RS06550	COG1433	Dinitrogenase iron-molybdenum cofactor
DND132_RS06575	COG1433	Dinitrogenase iron-molybdenum cofactor
DND132_RS06575	COG0535	radical SAM domain protein
DND132_RS06600	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
DND132_RS06605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DND132_RS06695	COG0798	PFAM Bile acid sodium symporter
DND132_RS06700	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DND132_RS06705	COG4175	Glycine betaine
DND132_RS06710	COG4176	ABC-type proline glycine betaine transport system permease component
DND132_RS06715	COG2113	Glycine betaine
DND132_RS06720	COG2204	response regulator
DND132_RS06735	COG2204	response regulator
DND132_RS06740	COG2204	response regulator
DND132_RS06745	COG0471	metal ion transport
DND132_RS06755	COG2204	response regulator
DND132_RS06770	COG2204	response regulator
DND132_RS06775	COG4191	Histidine kinase
DND132_RS06780	COG0745	RESPONSE REGULATOR receiver
DND132_RS06785	COG3852	Histidine kinase
DND132_RS06795	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DND132_RS06805	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DND132_RS06810	COG3842	ATPase activity
DND132_RS06815	COG1176	ABC-type spermidine putrescine transport system, permease component I
DND132_RS06820	COG1177	transmembrane transport
DND132_RS06830	COG3829	transcription factor binding
DND132_RS06840	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DND132_RS06845	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DND132_RS06850	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DND132_RS06865	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DND132_RS06870	COG4651	solute:proton antiporter activity
DND132_RS06870	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DND132_RS06890	COG2204	response regulator
DND132_RS06895	COG4191	Histidine kinase
DND132_RS06915	COG1555	photosystem II stabilization
DND132_RS06915	COG1596	polysaccharide export
DND132_RS06960	COG2204	response regulator
DND132_RS06965	COG3848	Pyruvate phosphate dikinase
DND132_RS06965	COG0574	Belongs to the PEP-utilizing enzyme family
DND132_RS06975	COG0730	response to heat
DND132_RS06985	COG2204	response regulator
DND132_RS06990	COG4191	Histidine kinase
DND132_RS07015	COG3852	Histidine kinase
DND132_RS07020	COG2204	response regulator
DND132_RS07040	COG2048	Heterodisulfide reductase, subunit B
DND132_RS07045	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DND132_RS07050	COG2201	protein-glutamate methylesterase activity
DND132_RS07115	COG1177	transmembrane transport
DND132_RS07120	COG1176	ABC-type spermidine putrescine transport system, permease component I
DND132_RS07130	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DND132_RS07135	COG4302	ethanolamine ammonia-lyase activity
DND132_RS07140	COG4303	Ethanolamine ammonia lyase large subunit
DND132_RS07160	COG0493	'glutamate synthase
DND132_RS07205	COG0848	biopolymer transport protein
DND132_RS07245	COG0765	amino acid transport
DND132_RS07250	COG4598	ABC transporter
DND132_RS07260	COG0829	nickel cation binding
DND132_RS07265	COG0831	urea catabolic process
DND132_RS07270	COG0832	Belongs to the urease beta subunit family
DND132_RS07275	COG0804	urea catabolic process
DND132_RS07280	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
DND132_RS07285	COG0830	nickel cation binding
DND132_RS07305	COG1074	ATP-dependent DNA helicase activity
DND132_RS07325	COG0601	transmembrane transport
DND132_RS07330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DND132_RS07345	COG0497	DNA recombination
DND132_RS07350	COG2095	MarC family integral membrane protein
DND132_RS07370	COG3153	acetyltransferase
DND132_RS07375	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DND132_RS07405	COG1595	DNA-templated transcription, initiation
DND132_RS07415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DND132_RS07430	COG1040	competence protein
DND132_RS07435	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DND132_RS07440	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DND132_RS07455	COG0583	DNA-binding transcription factor activity
DND132_RS07460	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DND132_RS07465	COG2814	Major facilitator Superfamily
DND132_RS07480	COG0528	UMP kinase activity
DND132_RS07495	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DND132_RS07510	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DND132_RS07525	COG0438	transferase activity, transferring glycosyl groups
DND132_RS07530	COG0463	Glycosyl transferase, family 2
DND132_RS07610	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DND132_RS07615	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
DND132_RS07645	COG1136	(ABC) transporter
DND132_RS07665	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DND132_RS07670	COG1846	Transcriptional regulator
DND132_RS07685	COG0840	transmembrane signaling receptor activity
DND132_RS07700	COG0848	biopolymer transport protein
DND132_RS07705	COG0811	peptide transport
DND132_RS07710	COG0523	cobalamin synthesis protein
DND132_RS07745	COG0437	4 iron, 4 sulfur cluster binding
DND132_RS07750	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DND132_RS07755	COG3842	ATPase activity
DND132_RS07775	COG1595	DNA-templated transcription, initiation
DND132_RS07820	COG0484	heat shock protein binding
DND132_RS07825	COG0437	4 iron, 4 sulfur cluster binding
DND132_RS07825	COG3064	Membrane
DND132_RS07830	COG5557	Pfam Polysulphide reductase, NrfD
DND132_RS07840	COG2181	nitrate reductase activity
DND132_RS07845	COG0247	lactate metabolic process
DND132_RS07855	COG2204	response regulator
DND132_RS07860	COG2204	response regulator
DND132_RS07865	COG2204	response regulator
DND132_RS07870	COG1959	2 iron, 2 sulfur cluster binding
DND132_RS07880	COG3005	denitrification pathway
DND132_RS07895	COG0492	ferredoxin-NADP+ reductase activity
DND132_RS07905	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DND132_RS07940	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DND132_RS07970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DND132_RS07975	COG2770	Histidine kinase
DND132_RS07975	COG2208	phosphoserine phosphatase activity
DND132_RS08015	COG3829	transcription factor binding
DND132_RS08025	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DND132_RS08055	COG2203	Gaf domain
DND132_RS08055	COG3706	GGDEF domain
DND132_RS08055	COG5001	Diguanylate cyclase
DND132_RS08055	COG4251	negative regulation of phosphorylation
DND132_RS08065	COG0557	exoribonuclease II activity
DND132_RS08070	COG1663	tetraacyldisaccharide 4'-kinase activity
DND132_RS08075	COG0670	Belongs to the BI1 family
DND132_RS08080	COG3304	Inner membrane component domain
DND132_RS08090	COG1785	Belongs to the alkaline phosphatase family
DND132_RS08095	COG2226	methyltransferase
DND132_RS08100	COG0180	Tryptophanyl-tRNA synthetase
DND132_RS08120	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DND132_RS08125	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DND132_RS08130	COG2814	Major facilitator Superfamily
DND132_RS08135	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DND132_RS08140	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DND132_RS08155	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DND132_RS08195	COG0733	neurotransmitter:sodium symporter activity
DND132_RS08215	COG1272	protein, Hemolysin III
DND132_RS08220	COG1959	2 iron, 2 sulfur cluster binding
DND132_RS08230	COG0310	cobalt ion transport
DND132_RS08240	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DND132_RS08270	COG0469	pyruvate kinase activity
DND132_RS08275	COG2001	Belongs to the MraZ family
DND132_RS08280	COG0275	rRNA processing
DND132_RS08295	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DND132_RS08300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DND132_RS08305	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DND132_RS08310	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DND132_RS08315	COG0772	Belongs to the SEDS family
DND132_RS08320	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DND132_RS08325	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DND132_RS08330	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DND132_RS08350	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DND132_RS08360	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DND132_RS08365	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DND132_RS08370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DND132_RS08380	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DND132_RS08390	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DND132_RS08400	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DND132_RS08410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DND132_RS08415	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DND132_RS08465	COG4191	Histidine kinase
DND132_RS08485	COG2131	deaminase
DND132_RS08510	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DND132_RS08515	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DND132_RS08520	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DND132_RS08520	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DND132_RS08545	COG2003	Belongs to the UPF0758 family
DND132_RS08550	COG1254	Belongs to the acylphosphatase family
DND132_RS08555	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DND132_RS08575	COG0181	hydroxymethylbilane synthase activity
DND132_RS08605	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DND132_RS08610	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DND132_RS08650	COG1022	Amp-dependent synthetase and ligase
DND132_RS08675	COG0243	molybdopterin cofactor binding
DND132_RS08685	COG2853	Lipoprotein
DND132_RS08690	COG3275	phosphorelay sensor kinase activity
DND132_RS08705	COG0481	GTPase activity
DND132_RS08710	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DND132_RS08725	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
DND132_RS08730	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DND132_RS08740	COG0616	signal peptide processing
DND132_RS08745	COG0436	Aminotransferase
DND132_RS08750	COG0840	transmembrane signaling receptor activity
DND132_RS08755	COG0129	dihydroxy-acid dehydratase activity
DND132_RS08765	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DND132_RS08770	COG0375	protein maturation
DND132_RS08775	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DND132_RS08790	COG0489	protein tyrosine kinase activity
DND132_RS08805	COG1392	Phosphate transport regulator
DND132_RS08810	COG0306	phosphate transporter
DND132_RS08815	COG5002	protein histidine kinase activity
DND132_RS08825	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DND132_RS08830	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DND132_RS08835	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DND132_RS08860	COG4895	conserved protein (DUF2196)
DND132_RS08865	COG1671	Belongs to the UPF0178 family
DND132_RS08875	COG1773	rubredoxin
DND132_RS08880	COG2033	superoxide reductase activity
DND132_RS08885	COG1592	Rubrerythrin
DND132_RS08895	COG0840	transmembrane signaling receptor activity
DND132_RS08900	COG0737	Belongs to the 5'-nucleotidase family
DND132_RS08905	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DND132_RS08910	COG0142	geranyltranstransferase activity
DND132_RS08930	COG2226	methyltransferase
DND132_RS08945	COG3045	CreA protein
DND132_RS08960	COG0653	protein targeting
DND132_RS08995	COG0277	FAD linked oxidase domain protein
DND132_RS09015	COG0328	RNA-DNA hybrid ribonuclease activity
DND132_RS09025	COG1136	(ABC) transporter
DND132_RS09025	COG0577	efflux transmembrane transporter activity
DND132_RS09030	COG1136	(ABC) transporter
DND132_RS09030	COG0577	efflux transmembrane transporter activity
DND132_RS09035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DND132_RS09045	COG0330	HflC and HflK could
DND132_RS09050	COG0330	HflC and HflK could
DND132_RS09060	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DND132_RS09075	COG5002	protein histidine kinase activity
DND132_RS09080	COG1280	lysine exporter protein (LysE YggA)
DND132_RS09085	COG0628	permease
DND132_RS09090	COG3830	Belongs to the UPF0237 family
DND132_RS09090	COG0560	Phosphoserine phosphatase
DND132_RS09105	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DND132_RS09110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DND132_RS09115	COG1120	ATPase activity
DND132_RS09125	COG5632	N-Acetylmuramoyl-L-alanine amidase
DND132_RS09125	COG3409	Peptidoglycan-binding domain 1 protein
DND132_RS09130	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DND132_RS09150	COG0326	Molecular chaperone. Has ATPase activity
DND132_RS09170	COG3594	Acyltransferase
DND132_RS09175	COG0686	Belongs to the AlaDH PNT family
DND132_RS09185	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
DND132_RS09195	COG5002	protein histidine kinase activity
DND132_RS09220	COG1530	ribonuclease E activity
DND132_RS09225	COG0731	radical SAM domain protein
DND132_RS09225	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DND132_RS09235	COG4122	O-methyltransferase activity
DND132_RS09240	COG3706	GGDEF domain
DND132_RS09275	COG1546	Belongs to the CinA family
DND132_RS09275	COG1058	Belongs to the CinA family
DND132_RS09320	COG0778	Nitroreductase
DND132_RS09340	COG2199	diguanylate cyclase activity
DND132_RS09355	COG2358	TRAP transporter, solute receptor (TAXI family
DND132_RS09370	COG0281	malic enzyme
DND132_RS09370	COG0280	phosphate acetyltransferase
DND132_RS09385	COG0708	Exodeoxyribonuclease III
DND132_RS09390	COG0693	protein deglycase activity
DND132_RS09395	COG2081	HI0933 family
DND132_RS09400	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DND132_RS09445	COG2208	phosphoserine phosphatase activity
DND132_RS09455	COG1136	(ABC) transporter
DND132_RS09480	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DND132_RS09500	COG1692	metallophosphoesterase
DND132_RS09510	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DND132_RS09515	COG0110	maltose O-acetyltransferase activity
DND132_RS09525	COG0018	arginyl-trna synthetase
DND132_RS09540	COG0697	spore germination
DND132_RS09570	COG1234	tRNA 3'-trailer cleavage
DND132_RS09580	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DND132_RS09585	COG0753	catalase activity
DND132_RS09595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DND132_RS09610	COG2815	serine threonine protein kinase
DND132_RS09610	COG0515	serine threonine protein kinase
DND132_RS09615	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DND132_RS09620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DND132_RS09630	COG0776	regulation of translation
DND132_RS09635	COG0537	adenosine 5'-monophosphoramidase activity
DND132_RS09640	COG0110	maltose O-acetyltransferase activity
DND132_RS09645	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DND132_RS09650	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DND132_RS09655	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DND132_RS09665	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DND132_RS09675	COG0860	N-Acetylmuramoyl-L-alanine amidase
DND132_RS09675	COG2247	cell wall binding repeat
DND132_RS09690	COG1111	helicase
DND132_RS09690	COG1205	dead DEAH box helicase
DND132_RS09710	COG2204	response regulator
DND132_RS09715	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DND132_RS09755	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DND132_RS09765	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DND132_RS09770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DND132_RS09785	COG2208	phosphoserine phosphatase activity
DND132_RS09800	COG0116	Belongs to the methyltransferase superfamily
DND132_RS09800	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DND132_RS09805	COG0697	spore germination
DND132_RS09880	COG3158	transport of potassium into the cell
DND132_RS09890	COG1607	acyl-coa hydrolase
DND132_RS09900	COG1489	DNA binding
DND132_RS09905	COG0346	lactoylglutathione lyase activity
DND132_RS09915	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DND132_RS09925	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DND132_RS09950	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DND132_RS09960	COG0004	ammonium transporteR
DND132_RS09965	COG0347	Belongs to the P(II) protein family
DND132_RS09970	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DND132_RS09975	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DND132_RS09980	COG0252	asparaginase activity
DND132_RS09985	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DND132_RS09995	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DND132_RS09995	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DND132_RS10020	COG0124	histidyl-tRNA synthetase
DND132_RS10025	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DND132_RS10030	COG0242	peptide deformylase activity
DND132_RS10050	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DND132_RS10055	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DND132_RS10065	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DND132_RS10085	COG1410	methionine synthase
DND132_RS10085	COG0646	methionine synthase
DND132_RS10110	COG0698	ribose 5-phosphate isomerase
DND132_RS10120	COG1494	fructose-1,6-bisphosphatase
DND132_RS10140	COG0084	hydrolase, TatD family'
DND132_RS10165	COG3290	protein histidine kinase activity
DND132_RS10165	COG3829	transcription factor binding
DND132_RS10170	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DND132_RS10175	COG1882	Formate acetyltransferase
DND132_RS10185	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DND132_RS10195	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DND132_RS10195	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DND132_RS10200	COG0656	L-ascorbic acid biosynthetic process
DND132_RS10205	COG0438	transferase activity, transferring glycosyl groups
DND132_RS10210	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DND132_RS10240	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DND132_RS10260	COG2078	PFAM AMMECR1 domain protein
DND132_RS10290	COG0432	Pfam Uncharacterised protein family UPF0047
DND132_RS10305	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DND132_RS10310	COG3422	double-strand break repair
DND132_RS10320	COG0525	valine-tRNA ligase activity
DND132_RS10335	COG0101	tRNA pseudouridine synthase activity
DND132_RS10355	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DND132_RS10360	COG1797	cobyrinic acid a,c-diamide synthase activity
DND132_RS10370	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DND132_RS10400	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DND132_RS10405	COG1127	ABC transporter
DND132_RS10410	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DND132_RS10420	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DND132_RS10435	COG1763	Mo-molybdopterin cofactor biosynthetic process
DND132_RS10450	COG0573	inorganic phosphate transmembrane transporter activity
DND132_RS10455	COG0581	inorganic phosphate transmembrane transporter activity
DND132_RS10460	COG0438	transferase activity, transferring glycosyl groups
DND132_RS10485	COG0517	IMP dehydrogenase activity
DND132_RS10520	COG0826	peptidase U32
DND132_RS10525	COG0613	PHP domain protein
DND132_RS10530	COG2835	tetraacyldisaccharide 4'-kinase activity
DND132_RS10545	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DND132_RS10550	COG1704	LemA family
DND132_RS10560	COG1739	Uncharacterized protein family UPF0029
DND132_RS10610	COG3258	Cytochrome c
DND132_RS10655	COG0746	molybdenum cofactor guanylyltransferase activity
DND132_RS10665	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DND132_RS10670	COG3426	butyrate kinase activity
DND132_RS10675	COG0280	phosphate acetyltransferase
DND132_RS10710	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DND132_RS10715	COG0728	peptidoglycan biosynthetic process
DND132_RS10720	COG2890	protein-(glutamine-N5) methyltransferase activity
DND132_RS10765	COG3118	belongs to the thioredoxin family
DND132_RS10825	COG1830	Aldolase
DND132_RS10830	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DND132_RS10835	COG1228	amidohydrolase
DND132_RS10845	COG2205	protein histidine kinase activity
DND132_RS10845	COG0784	Response regulator, receiver
DND132_RS10845	COG5002	protein histidine kinase activity
DND132_RS10850	COG0745	RESPONSE REGULATOR receiver
DND132_RS10855	COG0517	IMP dehydrogenase activity
DND132_RS10885	COG2197	response regulator
DND132_RS10895	COG0071	Belongs to the small heat shock protein (HSP20) family
DND132_RS10900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DND132_RS10910	COG0114	fumarate hydratase activity
DND132_RS10920	COG1705	Flagellar rod assembly protein muramidase FlgJ
DND132_RS10920	COG1388	LysM domain
DND132_RS10925	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DND132_RS10925	COG2199	diguanylate cyclase activity
DND132_RS10985	COG2205	protein histidine kinase activity
DND132_RS10985	COG2202	Pas domain
DND132_RS10990	COG1454	alcohol dehydrogenase
DND132_RS10995	COG0784	Response regulator, receiver
DND132_RS10995	COG5002	protein histidine kinase activity
DND132_RS10995	COG2198	Histidine kinase
DND132_RS11005	COG0384	phenazine biosynthesis protein PhzF
DND132_RS11010	COG1151	hydroxylamine reductase activity
DND132_RS11020	COG3437	response regulator, receiver
DND132_RS11020	COG0784	Response regulator, receiver
DND132_RS11030	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DND132_RS11035	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DND132_RS11040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DND132_RS11055	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DND132_RS11070	COG4974	Belongs to the 'phage' integrase family
DND132_RS11100	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DND132_RS11120	COG3645	SOS response
DND132_RS11155	COG2807	transmembrane transport
DND132_RS11170	COG0842	Transport permease protein
DND132_RS11175	COG0842	Transport permease protein
DND132_RS11175	COG1129	ABC transporter
DND132_RS11180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DND132_RS11185	COG1309	transcriptional regulator
DND132_RS11195	COG0840	transmembrane signaling receptor activity
DND132_RS11205	COG0247	lactate metabolic process
DND132_RS11225	COG0513	Belongs to the DEAD box helicase family
DND132_RS11235	COG0071	Belongs to the small heat shock protein (HSP20) family
DND132_RS11240	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
DND132_RS11255	COG2188	Transcriptional regulator
DND132_RS11260	COG3624	Phosphonate C-P lyase system protein PhnG
DND132_RS11270	COG3626	phosphonate metabolism
DND132_RS11275	COG3627	carbon phosphorus lyase activity
DND132_RS11280	COG4107	phosphonate C-P lyase system protein PhnK
DND132_RS11285	COG4778	phosphonate C-P lyase system protein PhnL
DND132_RS11290	COG3454	Phosphonate metabolism
DND132_RS11295	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DND132_RS11305	COG3639	organic phosphonate transmembrane transporter activity
DND132_RS11345	COG1309	transcriptional regulator
DND132_RS11350	COG0577	efflux transmembrane transporter activity
DND132_RS11350	COG1136	(ABC) transporter
DND132_RS11365	COG1691	(AIR) carboxylase
DND132_RS11370	COG1606	tRNA processing
DND132_RS11380	COG1846	Transcriptional regulator
DND132_RS11395	COG0205	6-phosphofructokinase activity
DND132_RS11405	COG1475	DNA binding
DND132_RS11415	COG1192	Involved in chromosome partitioning
DND132_RS11430	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DND132_RS11455	COG0674	pyruvate-flavodoxin oxidoreductase activity
DND132_RS11455	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DND132_RS11475	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DND132_RS11490	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DND132_RS11500	COG0438	transferase activity, transferring glycosyl groups
DND132_RS11510	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DND132_RS11515	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DND132_RS11525	COG0583	DNA-binding transcription factor activity
DND132_RS11530	COG0583	DNA-binding transcription factor activity
DND132_RS11540	COG2884	Cell division ATP-binding protein ftsE
DND132_RS11545	COG1592	Rubrerythrin
DND132_RS11555	COG0606	chelatase, subunit chli
DND132_RS11560	COG0840	transmembrane signaling receptor activity
DND132_RS11565	COG0784	Response regulator, receiver
DND132_RS11565	COG2205	protein histidine kinase activity
DND132_RS11565	COG2198	Histidine kinase
DND132_RS11585	COG0330	HflC and HflK could
DND132_RS11650	COG0589	response to stress
DND132_RS11675	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DND132_RS11680	COG0151	Belongs to the GarS family
DND132_RS11690	COG0724	RNA recognition motif
DND132_RS11695	COG0741	lytic transglycosylase activity
DND132_RS11700	COG2208	phosphoserine phosphatase activity
DND132_RS11720	COG3383	formate dehydrogenase (NAD+) activity
DND132_RS11750	COG1280	lysine exporter protein (LysE YggA)
DND132_RS11775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DND132_RS11815	COG5002	protein histidine kinase activity
DND132_RS11815	COG3850	Histidine kinase
DND132_RS11835	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DND132_RS11840	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DND132_RS11850	COG0295	cytidine deaminase activity
DND132_RS11855	COG1079	Belongs to the binding-protein-dependent transport system permease family
DND132_RS11860	COG4603	Belongs to the binding-protein-dependent transport system permease family
DND132_RS11865	COG3845	ABC transporter
DND132_RS11870	COG1744	ABC transporter substrate-binding protein PnrA-like
DND132_RS11875	COG1744	ABC transporter substrate-binding protein PnrA-like
DND132_RS11885	COG2304	oxidoreductase activity
DND132_RS11940	COG0438	transferase activity, transferring glycosyl groups
DND132_RS11980	COG1696	Membrane protein involved in D-alanine export
DND132_RS12040	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DND132_RS12045	COG0546	phosphoglycolate phosphatase activity
DND132_RS12055	COG2414	aldehyde ferredoxin oxidoreductase
DND132_RS12070	COG0163	prenyltransferase activity
DND132_RS12075	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DND132_RS12080	COG0583	DNA-binding transcription factor activity
DND132_RS12095	COG1090	epimerase
DND132_RS12100	COG5000	phosphorelay sensor kinase activity
DND132_RS12125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DND132_RS12130	COG1120	ATPase activity
DND132_RS12135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DND132_RS12140	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DND132_RS12165	COG0275	rRNA processing
DND132_RS12175	COG1846	Transcriptional regulator
DND132_RS12185	COG2204	response regulator
DND132_RS12190	COG0644	oxidoreductase
DND132_RS12205	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DND132_RS12205	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DND132_RS12230	COG1216	Glycosyl transferase, family 2
DND132_RS12230	COG1442	glycosyl transferase family 8
DND132_RS12250	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DND132_RS12255	COG1088	dTDP-glucose 4,6-dehydratase activity
DND132_RS12290	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DND132_RS12315	COG0540	Belongs to the ATCase OTCase family
DND132_RS12320	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DND132_RS12335	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DND132_RS12345	COG0148	phosphopyruvate hydratase activity
DND132_RS12365	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DND132_RS12395	COG0714	Associated with various cellular activities
DND132_RS12475	COG2204	response regulator
DND132_RS12520	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DND132_RS12545	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DND132_RS12555	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DND132_RS12560	COG0668	transmembrane transport
DND132_RS12575	COG1846	Transcriptional regulator
DND132_RS12580	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DND132_RS12590	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DND132_RS12600	COG0709	Synthesizes selenophosphate from selenide and ATP
DND132_RS12605	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DND132_RS12610	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DND132_RS12645	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DND132_RS12650	COG0861	Integral membrane protein TerC family
DND132_RS12655	COG2226	methyltransferase
DND132_RS12725	COG1902	pentaerythritol trinitrate reductase activity
DND132_RS12740	COG0432	Pfam Uncharacterised protein family UPF0047
DND132_RS12745	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DND132_RS12750	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DND132_RS12765	COG0539	negative regulation of cytoplasmic translation
DND132_RS12770	COG0616	signal peptide processing
DND132_RS12825	COG0778	Nitroreductase
DND132_RS12830	COG1733	regulation of RNA biosynthetic process
DND132_RS12845	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DND132_RS12860	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DND132_RS12865	COG4191	Histidine kinase
DND132_RS12865	COG0784	Response regulator, receiver
DND132_RS12890	COG1683	Conserved Protein
DND132_RS12915	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DND132_RS12920	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DND132_RS12925	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DND132_RS12930	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DND132_RS12935	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DND132_RS12945	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DND132_RS12955	COG0772	Belongs to the SEDS family
DND132_RS12960	COG0768	penicillin binding
DND132_RS12975	COG1077	Cell shape determining protein MreB Mrl
DND132_RS12980	COG1242	4 iron, 4 sulfur cluster binding
DND132_RS13010	COG2814	Major facilitator Superfamily
DND132_RS13020	COG0543	2 iron, 2 sulfur cluster binding
DND132_RS13025	COG0493	'glutamate synthase
DND132_RS13030	COG2358	TRAP transporter, solute receptor (TAXI family
DND132_RS13035	COG3279	Response regulator of the LytR AlgR family
DND132_RS13040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DND132_RS13055	COG3047	cAMP biosynthetic process
DND132_RS13055	COG2885	chlorophyll binding
DND132_RS13070	COG0243	molybdopterin cofactor binding
DND132_RS13075	COG0437	4 iron, 4 sulfur cluster binding
DND132_RS13085	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DND132_RS13105	COG1937	Protein conserved in bacteria
DND132_RS13140	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DND132_RS13140	COG0519	Catalyzes the synthesis of GMP from XMP
DND132_RS13145	COG0501	Belongs to the peptidase M48B family
DND132_RS13155	COG1228	amidohydrolase
DND132_RS13170	COG2204	response regulator
DND132_RS13175	COG0438	transferase activity, transferring glycosyl groups
DND132_RS13200	COG1366	Belongs to the anti-sigma-factor antagonist family
DND132_RS13205	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DND132_RS13210	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
DND132_RS13225	COG1294	oxidase, subunit
DND132_RS13230	COG1271	oxidase subunit
DND132_RS13245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DND132_RS13250	COG2226	methyltransferase
DND132_RS13255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DND132_RS13260	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DND132_RS13285	COG0697	spore germination
DND132_RS13295	COG2046	Belongs to the sulfate adenylyltransferase family
DND132_RS13315	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DND132_RS13335	COG4221	oxidoreductase activity
DND132_RS13370	COG0589	response to stress
DND132_RS13375	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DND132_RS13380	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DND132_RS13395	COG2169	Transcriptional regulator
DND132_RS13395	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DND132_RS13410	COG4191	Histidine kinase
DND132_RS13415	COG0166	Belongs to the GPI family
DND132_RS13435	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DND132_RS13440	COG0702	epimerase
DND132_RS13450	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DND132_RS13455	COG1522	sequence-specific DNA binding
DND132_RS13460	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DND132_RS13485	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DND132_RS13510	COG0348	domain, Protein
DND132_RS13520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DND132_RS13525	COG2135	peptidase activity
DND132_RS13530	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DND132_RS13535	COG0228	four-way junction DNA binding
DND132_RS13540	COG1837	Belongs to the UPF0109 family
DND132_RS13545	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DND132_RS13550	COG0336	Belongs to the RNA methyltransferase TrmD family
DND132_RS13550	COG4752	Belongs to the RNA methyltransferase TrmD family
DND132_RS13580	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DND132_RS13585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DND132_RS13590	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DND132_RS13600	COG1268	BioY protein
DND132_RS13605	COG1268	BioY protein
DND132_RS13610	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DND132_RS13620	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DND132_RS13625	COG0792	nuclease activity
DND132_RS13630	COG0673	inositol 2-dehydrogenase activity
DND132_RS13635	COG0390	transport system, permease component
DND132_RS13640	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DND132_RS13655	COG0318	PFAM AMP-dependent synthetase and ligase
DND132_RS13665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DND132_RS13670	COG1914	H( )-stimulated, divalent metal cation uptake system
DND132_RS13680	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DND132_RS13695	COG1067	ATP-dependent peptidase activity
DND132_RS13720	COG4946	Tricorn protease homolog
DND132_RS13720	COG0823	Involved in the tonB-independent uptake of proteins
DND132_RS13720	COG1506	peptidase
DND132_RS13725	COG1987	bacterial-type flagellum assembly
DND132_RS13730	COG1338	Plays a role in the flagellum-specific transport system
DND132_RS13760	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DND132_RS13765	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DND132_RS13775	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DND132_RS13785	COG0215	cysteine-tRNA ligase activity
DND132_RS13805	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DND132_RS13820	COG2207	Transcriptional regulator
DND132_RS13825	COG0506	proline dehydrogenase activity
DND132_RS13830	COG0857	belongs to the CobB CobQ family
DND132_RS13835	COG1042	CoA-binding domain protein
DND132_RS13835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DND132_RS13835	COG0045	succinate-CoA ligase (ADP-forming) activity
DND132_RS13840	COG0571	ribonuclease III activity
DND132_RS13850	COG1749	Flagellar hook protein flgE
DND132_RS13855	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DND132_RS13880	COG1490	D-aminoacyl-tRNA deacylase activity
DND132_RS13890	COG0720	synthase
DND132_RS13925	COG0471	metal ion transport
DND132_RS13985	COG0745	RESPONSE REGULATOR receiver
DND132_RS13995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DND132_RS14025	COG1335	isochorismatase
DND132_RS14035	COG1346	cytolysis
DND132_RS14040	COG1380	Effector of murein hydrolase LrgA
DND132_RS14045	COG0583	DNA-binding transcription factor activity
DND132_RS14050	COG1012	belongs to the aldehyde dehydrogenase family
DND132_RS14065	COG0167	dihydroorotate dehydrogenase activity
DND132_RS14070	COG0543	2 iron, 2 sulfur cluster binding
DND132_RS14080	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DND132_RS14085	COG0418	dihydroorotase activity
DND132_RS14095	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DND132_RS14160	COG2221	Nitrite and sulphite reductase 4Fe-4S
DND132_RS14165	COG2221	Nitrite and sulphite reductase 4Fe-4S
DND132_RS14175	COG1797	cobyrinic acid a,c-diamide synthase activity
DND132_RS14225	COG0318	PFAM AMP-dependent synthetase and ligase
DND132_RS14235	COG2089	acid synthase
DND132_RS14240	COG0835	chemotaxis
DND132_RS14240	COG0784	Response regulator, receiver
DND132_RS14260	COG0459	protein refolding
DND132_RS14265	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DND132_RS14270	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DND132_RS14290	COG0791	NLP P60 protein
DND132_RS14340	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DND132_RS14350	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DND132_RS14350	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
DND132_RS14370	COG2414	aldehyde ferredoxin oxidoreductase
DND132_RS14375	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DND132_RS14380	COG1546	Belongs to the CinA family
DND132_RS14380	COG1058	Belongs to the CinA family
DND132_RS14415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DND132_RS14420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DND132_RS14430	COG0433	COG0433 Predicted ATPase
DND132_RS14455	COG0857	belongs to the CobB CobQ family
DND132_RS14455	COG0280	phosphate acetyltransferase
DND132_RS14465	COG4657	Part of a membrane complex involved in electron transport
DND132_RS14470	COG4660	Part of a membrane complex involved in electron transport
DND132_RS14475	COG4659	FMN binding
DND132_RS14480	COG4658	electron transport chain
DND132_RS14495	COG0471	metal ion transport
DND132_RS14500	COG0280	phosphate acetyltransferase
DND132_RS14500	COG0281	malic enzyme
DND132_RS14515	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DND132_RS14520	COG1053	succinate dehydrogenase
DND132_RS14535	COG4191	Histidine kinase
DND132_RS14550	COG0288	reversible hydration of carbon dioxide
DND132_RS14580	COG0598	Magnesium transport protein CorA
DND132_RS14595	COG0189	ligase activity
DND132_RS14600	COG4067	protein conserved in archaea
DND132_RS14600	COG0189	ligase activity
DND132_RS14615	COG1879	ABC-type sugar transport system periplasmic component
DND132_RS14625	COG0784	Response regulator, receiver
DND132_RS14625	COG5002	protein histidine kinase activity
DND132_RS14625	COG2205	protein histidine kinase activity
DND132_RS14630	COG1079	Belongs to the binding-protein-dependent transport system permease family
DND132_RS14635	COG4603	Belongs to the binding-protein-dependent transport system permease family
DND132_RS14650	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DND132_RS14660	COG0564	pseudouridine synthase activity
DND132_RS14670	COG0668	transmembrane transport
DND132_RS14780	COG0737	Belongs to the 5'-nucleotidase family
DND132_RS14790	COG3123	guanosine phosphorylase activity
DND132_RS14800	COG1085	galactose-1-phosphate uridylyltransferase
DND132_RS14810	COG1609	Transcriptional regulator
DND132_RS14820	COG3842	ATPase activity
DND132_RS14830	COG1175	transmembrane transport
DND132_RS14835	COG0395	ABC-type sugar transport system, permease component
DND132_RS14860	COG2204	response regulator
DND132_RS14880	COG4964	Belongs to the GSP D family
DND132_RS14925	COG1840	ABC-type Fe3 transport system, periplasmic component
DND132_RS14930	COG3842	ATPase activity
DND132_RS14935	COG1178	ABC-type Fe3 transport system permease component
DND132_RS14965	COG0745	RESPONSE REGULATOR receiver
DND132_RS14970	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DND132_RS14980	COG0784	Response regulator, receiver
DND132_RS14980	COG0835	chemotaxis
DND132_RS14990	COG2205	protein histidine kinase activity
DND132_RS15015	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DND132_RS15055	COG0175	sulfate reduction
DND132_RS15060	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DND132_RS15060	COG2111	Na H antiporter
DND132_RS15070	COG3260	NADH ubiquinone oxidoreductase 20
DND132_RS15075	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DND132_RS15080	COG3261	NADH dehydrogenase
DND132_RS15080	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
DND132_RS15100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DND132_RS15110	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DND132_RS15115	COG0442	prolyl-tRNA aminoacylation
DND132_RS15120	COG1280	lysine exporter protein (LysE YggA)
DND132_RS15125	COG1570	exodeoxyribonuclease VII activity
DND132_RS15130	COG0741	lytic transglycosylase activity
DND132_RS15130	COG0739	heme binding
DND132_RS15130	COG1196	nuclear chromosome segregation
DND132_RS15140	COG1722	exodeoxyribonuclease VII activity
DND132_RS15145	COG0142	geranyltranstransferase activity
DND132_RS15150	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DND132_RS15160	COG3012	SEC-C Motif Domain Protein
DND132_RS15165	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DND132_RS15195	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DND132_RS15220	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DND132_RS15240	COG2204	response regulator
DND132_RS15250	COG0574	Belongs to the PEP-utilizing enzyme family
DND132_RS15250	COG3848	Pyruvate phosphate dikinase
DND132_RS15320	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DND132_RS15325	COG0109	protoheme IX farnesyltransferase activity
DND132_RS15345	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DND132_RS15365	COG0437	4 iron, 4 sulfur cluster binding
DND132_RS15395	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DND132_RS15415	COG1256	bacterial-type flagellum assembly
DND132_RS15420	COG1749	Flagellar hook protein flgE
DND132_RS15435	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DND132_RS15440	COG0745	RESPONSE REGULATOR receiver
DND132_RS15455	COG2205	protein histidine kinase activity
DND132_RS15460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DND132_RS15465	COG1566	PFAM secretion protein HlyD family protein
DND132_RS15480	COG1177	transmembrane transport
DND132_RS15490	COG3842	ATPase activity
DND132_RS15525	COG2204	response regulator
DND132_RS15540	COG0438	transferase activity, transferring glycosyl groups
DND132_RS15565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DND132_RS15570	COG0437	4 iron, 4 sulfur cluster binding
DND132_RS15570	COG3064	Membrane
DND132_RS15575	COG5557	Pfam Polysulphide reductase, NrfD
DND132_RS15595	COG3381	protein complex oligomerization
DND132_RS15600	COG0243	molybdopterin cofactor binding
DND132_RS15605	COG0437	4 iron, 4 sulfur cluster binding
DND132_RS15620	COG0508	dehydrogenase complex catalyzes the overall conversion of
DND132_RS15630	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DND132_RS15635	COG0022	dehydrogenase e1 component
DND132_RS15650	COG2050	protein possibly involved in aromatic compounds catabolism
DND132_RS15650	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DND132_RS15670	COG4585	Histidine kinase
DND132_RS15675	COG2197	response regulator
DND132_RS15720	COG1518	maintenance of DNA repeat elements
DND132_RS15730	COG1305	Transglutaminase-like
DND132_RS15745	COG2308	Evidence 4 Homologs of previously reported genes of
DND132_RS15765	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DND132_RS15775	COG0765	amino acid transport
DND132_RS15785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DND132_RS15795	COG1228	amidohydrolase
DND132_RS15800	COG2188	Transcriptional regulator
DND132_RS15815	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DND132_RS15845	COG4957	zinc ion binding
DND132_RS15910	COG0668	transmembrane transport
DND132_RS15920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DND132_RS15920	COG1042	CoA-binding domain protein
DND132_RS15920	COG0045	succinate-CoA ligase (ADP-forming) activity
DND132_RS15925	COG1942	4-Oxalocrotonate Tautomerase
DND132_RS15935	COG0010	Belongs to the arginase family
DND132_RS15940	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DND132_RS15945	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DND132_RS15970	COG4783	chaperone-mediated protein folding
DND132_RS15975	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DND132_RS15985	COG0193	aminoacyl-tRNA hydrolase activity
DND132_RS15990	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DND132_RS15995	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DND132_RS16005	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DND132_RS16020	COG5002	protein histidine kinase activity
DND132_RS16025	COG0513	Belongs to the DEAD box helicase family
DND132_RS16030	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DND132_RS16035	COG0724	RNA recognition motif
DND132_RS16050	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DND132_RS16065	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DND132_RS16070	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DND132_RS16075	COG0159	tryptophan synthase activity
DND132_RS16080	COG0133	tryptophan synthase activity
DND132_RS16085	COG0135	phosphoribosylanthranilate isomerase activity
DND132_RS16090	COG0134	indole-3-glycerol-phosphate synthase activity
DND132_RS16095	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DND132_RS16105	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DND132_RS16110	COG2084	Dehydrogenase
DND132_RS16115	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DND132_RS16120	COG1605	Chorismate mutase
DND132_RS16120	COG0077	Prephenate dehydratase
DND132_RS16125	COG1465	3-dehydroquinate synthase
DND132_RS16130	COG1830	Aldolase
DND132_RS16135	COG0004	ammonium transporteR
DND132_RS16140	COG0347	Belongs to the P(II) protein family
DND132_RS16145	COG2200	EAL domain
DND132_RS16150	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DND132_RS16155	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DND132_RS16160	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DND132_RS16165	COG5001	Diguanylate cyclase
DND132_RS16170	COG0501	Belongs to the peptidase M48B family
DND132_RS16185	COG0583	DNA-binding transcription factor activity
DND132_RS16200	COG0459	protein refolding
DND132_RS16225	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
DND132_RS16250	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DND132_RS16265	COG1847	R3H domain protein
DND132_RS16270	COG0706	membrane insertase activity
DND132_RS16275	COG0594	ribonuclease P activity
DND132_RS16295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DND132_RS16300	COG3706	GGDEF domain
DND132_RS16315	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
DND132_RS16335	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
DND132_RS16345	COG0028	Belongs to the TPP enzyme family
DND132_RS16350	COG0538	isocitrate dehydrogenase activity
DND132_RS16355	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DND132_RS16365	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DND132_RS16375	COG1472	Belongs to the glycosyl hydrolase 3 family
DND132_RS16385	COG1121	(ABC) transporter
DND132_RS16390	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DND132_RS16420	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DND132_RS16430	COG3118	belongs to the thioredoxin family
DND132_RS16455	COG1328	CTP reductase activity
DND132_RS16455	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DND132_RS16470	COG0668	transmembrane transport
DND132_RS16475	COG1408	metallophosphoesterase
DND132_RS16480	COG0531	amino acid
DND132_RS16485	COG2186	Transcriptional regulator
DND132_RS16490	COG1304	FMN binding
DND132_RS16495	COG0730	response to heat
DND132_RS16510	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DND132_RS16545	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DND132_RS16560	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DND132_RS16560	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DND132_RS16590	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DND132_RS16595	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DND132_RS16610	COG1253	flavin adenine dinucleotide binding
DND132_RS16615	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DND132_RS16620	COG1138	Cytochrome C-type biogenesis protein
DND132_RS16625	COG1131	(ABC) transporter
DND132_RS16635	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DND132_RS16645	COG0683	leucine binding
DND132_RS16650	COG0559	Belongs to the binding-protein-dependent transport system permease family
DND132_RS16670	COG0517	IMP dehydrogenase activity
DND132_RS16670	COG0516	GMP reductase activity
DND132_RS16675	COG0519	Catalyzes the synthesis of GMP from XMP
DND132_RS16680	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DND132_RS16685	COG0805	protein transport
DND132_RS16690	COG0131	Imidazoleglycerol-phosphate dehydratase
DND132_RS16700	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DND132_RS16705	COG0668	transmembrane transport
DND132_RS16710	COG0463	Glycosyl transferase, family 2
DND132_RS16720	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DND132_RS16725	COG0564	pseudouridine synthase activity
DND132_RS16740	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
DND132_RS16765	COG0542	response to heat
DND132_RS16770	COG2814	Major facilitator Superfamily
DND132_RS16790	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DND132_RS16795	COG0443	Heat shock 70 kDa protein
DND132_RS16810	COG0154	amidase activity
DND132_RS16820	COG0482	sulfurtransferase activity
DND132_RS16830	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DND132_RS16840	COG1561	YicC-like family, N-terminal region
DND132_RS16845	COG2052	Domain of unknown function (DUF370)
DND132_RS16850	COG0194	GDP metabolic process
DND132_RS16855	COG0284	orotidine-5'-phosphate decarboxylase activity
DND132_RS16865	COG1639	'signal transduction protein
DND132_RS16870	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DND132_RS16875	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DND132_RS16880	COG0321	lipoyl(octanoyl) transferase activity
DND132_RS16900	COG4822	anaerobic cobalamin biosynthetic process
DND132_RS16915	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DND132_RS16920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DND132_RS16925	COG4822	anaerobic cobalamin biosynthetic process
DND132_RS16930	COG0643	Histidine kinase
DND132_RS16930	COG2198	Histidine kinase
DND132_RS16940	COG2204	response regulator
DND132_RS16945	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DND132_RS16950	COG0009	L-threonylcarbamoyladenylate synthase
DND132_RS16960	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DND132_RS16975	COG0505	Belongs to the CarA family
DND132_RS16980	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DND132_RS16990	COG1181	Belongs to the D-alanine--D-alanine ligase family
DND132_RS17015	COG0784	Response regulator, receiver
DND132_RS17015	COG0835	chemotaxis
DND132_RS17020	COG3116	cell division
DND132_RS17020	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DND132_RS17040	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DND132_RS17055	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DND132_RS17060	COG0250	Participates in transcription elongation, termination and antitermination
DND132_RS17065	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DND132_RS17070	COG0081	regulation of translation
DND132_RS17075	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DND132_RS17080	COG0222	ribosome binding
DND132_RS17085	COG0085	RNA polymerase activity
DND132_RS17090	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DND132_RS17095	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DND132_RS17100	COG0049	tRNA binding
DND132_RS17105	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DND132_RS17110	COG0051	transcription antitermination factor activity, RNA binding
DND132_RS17115	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DND132_RS17120	COG0088	Forms part of the polypeptide exit tunnel
DND132_RS17125	COG0089	rRNA binding
DND132_RS17130	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DND132_RS17135	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DND132_RS17140	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DND132_RS17145	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DND132_RS17150	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DND132_RS17155	COG0255	Belongs to the universal ribosomal protein uL29 family
DND132_RS17160	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DND132_RS17165	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DND132_RS17175	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DND132_RS17180	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DND132_RS17190	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DND132_RS17195	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DND132_RS17200	COG1841	ribosomal large subunit assembly
DND132_RS17205	COG0200	Binds to the 23S rRNA
DND132_RS17210	COG0201	protein transport
DND132_RS17220	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DND132_RS17225	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DND132_RS17230	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DND132_RS17235	COG0202	RNA polymerase activity
DND132_RS17240	COG0203	ribosomal protein L17
DND132_RS17255	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DND132_RS17260	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DND132_RS17265	COG1309	transcriptional regulator
DND132_RS17270	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DND132_RS17275	COG0697	spore germination
DND132_RS17285	COG3028	Belongs to the UPF0307 family
DND132_RS17300	COG1127	ABC transporter
DND132_RS17305	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DND132_RS17315	COG1012	belongs to the aldehyde dehydrogenase family
DND132_RS17320	COG1309	transcriptional regulator
DND132_RS17325	COG0659	secondary active sulfate transmembrane transporter activity
DND132_RS17330	COG2204	response regulator
DND132_RS17335	COG5002	protein histidine kinase activity
DND132_RS17350	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
DND132_RS17360	COG0488	(ABC) transporter
DND132_RS17365	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DND132_RS17375	COG1522	sequence-specific DNA binding
DND132_RS17380	COG0535	radical SAM domain protein
DND132_RS17385	COG0113	porphobilinogen synthase activity
DND132_RS17390	COG0535	radical SAM domain protein
DND132_RS17415	COG0438	transferase activity, transferring glycosyl groups
DND132_RS17425	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DND132_RS17425	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DND132_RS17430	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DND132_RS17455	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DND132_RS17460	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
DND132_RS17535	COG0784	Response regulator, receiver
DND132_RS17535	COG2205	protein histidine kinase activity
DND132_RS17535	COG2198	Histidine kinase
DND132_RS17550	COG0784	Response regulator, receiver
DND132_RS17550	COG2205	protein histidine kinase activity
DND132_RS17550	COG5002	protein histidine kinase activity
DND132_RS17555	COG0463	Glycosyl transferase, family 2
DND132_RS17555	COG1216	Glycosyl transferase, family 2
DND132_RS17570	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DND132_RS17575	COG2414	aldehyde ferredoxin oxidoreductase
DND132_RS17585	COG0811	peptide transport
DND132_RS17590	COG0811	peptide transport
DND132_RS17595	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
DND132_RS17620	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DND132_RS17650	COG5002	protein histidine kinase activity
DND132_RS17680	COG2339	peptidase activity
DND132_RS17690	COG0840	transmembrane signaling receptor activity
DND132_RS17735	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DND132_RS17740	COG0500	methyltransferase
DND132_RS17755	COG0739	heme binding
DND132_RS17755	COG1196	nuclear chromosome segregation
DND132_RS17755	COG0741	lytic transglycosylase activity
DND132_RS17760	COG2205	protein histidine kinase activity
DND132_RS17760	COG0784	Response regulator, receiver
DND132_RS17765	COG2205	protein histidine kinase activity
DND132_RS17765	COG0784	Response regulator, receiver
DND132_RS17800	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DND132_RS17815	COG2205	protein histidine kinase activity
DND132_RS17815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DND132_RS17840	COG0671	phosphoesterase, PA-phosphatase related
DND132_RS17850	COG1309	transcriptional regulator
DND132_RS17855	COG2205	protein histidine kinase activity
DND132_RS17855	COG0784	Response regulator, receiver
DND132_RS17885	COG4106	trans-aconitate 2-methyltransferase activity