locus-tag	class	description
DMR_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DMR_RS00020	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DMR_RS00035	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DMR_RS00050	COG0330	HflC and HflK could
DMR_RS00065	COG1192	Involved in chromosome partitioning
DMR_RS00075	COG1475	DNA binding
DMR_RS00090	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DMR_RS00125	COG0129	dihydroxy-acid dehydratase activity
DMR_RS00135	COG0124	histidyl-tRNA synthetase
DMR_RS00140	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DMR_RS00145	COG0242	peptide deformylase activity
DMR_RS00150	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DMR_RS00160	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DMR_RS00160	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DMR_RS00165	COG1902	pentaerythritol trinitrate reductase activity
DMR_RS00170	COG0840	transmembrane signaling receptor activity
DMR_RS00200	COG1027	Aspartate ammonia-lyase
DMR_RS00215	COG0058	SHG alpha-glucan phosphorylase activity
DMR_RS00220	COG5001	Diguanylate cyclase
DMR_RS00220	COG5002	protein histidine kinase activity
DMR_RS00220	COG3447	MASE1 domain protein
DMR_RS00250	COG2204	response regulator
DMR_RS00255	COG1218	3'(2'),5'-bisphosphate nucleotidase
DMR_RS00275	COG0367	asparagine synthase
DMR_RS00285	COG0784	Response regulator, receiver
DMR_RS00285	COG0835	chemotaxis
DMR_RS00300	COG0288	reversible hydration of carbon dioxide
DMR_RS00320	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DMR_RS00325	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DMR_RS00340	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DMR_RS00350	COG0617	tRNA 3'-terminal CCA addition
DMR_RS00355	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DMR_RS00360	COG0540	Belongs to the ATCase OTCase family
DMR_RS00365	COG4822	anaerobic cobalamin biosynthetic process
DMR_RS00370	COG2177	Part of the ABC transporter FtsEX involved in
DMR_RS00375	COG2884	Cell division ATP-binding protein ftsE
DMR_RS00380	COG0497	DNA recombination
DMR_RS00385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMR_RS00390	COG0601	transmembrane transport
DMR_RS00460	COG0582	viral genome integration into host DNA
DMR_RS00510	COG2207	Transcriptional regulator
DMR_RS00515	COG1979	alcohol dehydrogenase
DMR_RS00595	COG0745	RESPONSE REGULATOR receiver
DMR_RS00655	COG0724	RNA recognition motif
DMR_RS00670	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DMR_RS00675	COG0569	domain protein
DMR_RS00685	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DMR_RS00700	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DMR_RS00705	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DMR_RS00720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DMR_RS00740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DMR_RS00745	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DMR_RS00750	COG1454	alcohol dehydrogenase
DMR_RS00760	COG2048	Heterodisulfide reductase, subunit B
DMR_RS00765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DMR_RS00800	COG3852	Histidine kinase
DMR_RS00805	COG2204	response regulator
DMR_RS00815	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DMR_RS00830	COG0525	valine-tRNA ligase activity
DMR_RS00840	COG5001	Diguanylate cyclase
DMR_RS00840	COG3300	MHYT domain
DMR_RS00850	COG0517	IMP dehydrogenase activity
DMR_RS00860	COG0655	NAD(P)H dehydrogenase (quinone) activity
DMR_RS00865	COG2274	protein secretion by the type I secretion system
DMR_RS00870	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DMR_RS00880	COG0579	oxidoreductase
DMR_RS00885	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DMR_RS00890	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DMR_RS00905	COG1794	racemase activity, acting on amino acids and derivatives
DMR_RS00915	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DMR_RS00935	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DMR_RS00940	COG0776	regulation of translation
DMR_RS00945	COG0537	adenosine 5'-monophosphoramidase activity
DMR_RS00960	COG0402	S-adenosylhomocysteine deaminase activity
DMR_RS00965	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DMR_RS00980	COG1335	isochorismatase
DMR_RS01000	COG3852	Histidine kinase
DMR_RS01005	COG2204	response regulator
DMR_RS01010	COG5001	Diguanylate cyclase
DMR_RS01010	COG4251	negative regulation of phosphorylation
DMR_RS01010	COG3706	GGDEF domain
DMR_RS01010	COG2203	Gaf domain
DMR_RS01020	COG0840	transmembrane signaling receptor activity
DMR_RS01050	COG1027	Aspartate ammonia-lyase
DMR_RS01055	COG1686	Belongs to the peptidase S11 family
DMR_RS01060	COG5002	protein histidine kinase activity
DMR_RS01115	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DMR_RS01120	COG5002	protein histidine kinase activity
DMR_RS01125	COG0745	RESPONSE REGULATOR receiver
DMR_RS01135	COG5002	protein histidine kinase activity
DMR_RS01145	COG1492	cobalamin metabolic process
DMR_RS01160	COG0459	protein refolding
DMR_RS01165	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DMR_RS01170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DMR_RS01170	COG2111	Na H antiporter
DMR_RS01175	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DMR_RS01180	COG3260	NADH ubiquinone oxidoreductase 20
DMR_RS01190	COG3261	NADH dehydrogenase
DMR_RS01190	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
DMR_RS01205	COG0470	DNA polymerase III
DMR_RS01215	COG0529	Catalyzes the synthesis of activated sulfate
DMR_RS01215	COG2046	Belongs to the sulfate adenylyltransferase family
DMR_RS01225	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DMR_RS01230	COG3437	response regulator, receiver
DMR_RS01235	COG2198	Histidine kinase
DMR_RS01235	COG0643	Histidine kinase
DMR_RS01275	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
DMR_RS01295	COG0784	Response regulator, receiver
DMR_RS01295	COG2205	protein histidine kinase activity
DMR_RS01295	COG2198	Histidine kinase
DMR_RS01305	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DMR_RS01310	COG1215	transferase activity, transferring glycosyl groups
DMR_RS01330	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
DMR_RS01350	COG2274	protein secretion by the type I secretion system
DMR_RS01355	COG0438	transferase activity, transferring glycosyl groups
DMR_RS01375	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DMR_RS01380	COG1079	Belongs to the binding-protein-dependent transport system permease family
DMR_RS01390	COG1129	ABC transporter
DMR_RS01395	COG1744	ABC transporter substrate-binding protein PnrA-like
DMR_RS01415	COG0438	transferase activity, transferring glycosyl groups
DMR_RS01435	COG0138	bifunctional purine biosynthesis protein purh
DMR_RS01445	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DMR_RS01490	COG0438	transferase activity, transferring glycosyl groups
DMR_RS01560	COG0488	(ABC) transporter
DMR_RS01620	COG2221	Nitrite and sulphite reductase 4Fe-4S
DMR_RS01625	COG2221	Nitrite and sulphite reductase 4Fe-4S
DMR_RS01635	COG1797	cobyrinic acid a,c-diamide synthase activity
DMR_RS01705	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DMR_RS01715	COG0346	lactoylglutathione lyase activity
DMR_RS01720	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DMR_RS01750	COG1214	PFAM Peptidase M22, glycoprotease
DMR_RS01755	COG0750	zinc metalloprotease
DMR_RS01760	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DMR_RS01770	COG0575	Belongs to the CDS family
DMR_RS01790	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DMR_RS01815	COG1516	flagellar protein fliS
DMR_RS01820	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DMR_RS01820	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DMR_RS01825	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DMR_RS01845	COG4566	intracellular signal transduction
DMR_RS01865	COG2204	response regulator
DMR_RS01980	COG1720	tRNA m6t6A37 methyltransferase activity
DMR_RS01990	COG0840	transmembrane signaling receptor activity
DMR_RS01995	COG2201	protein-glutamate methylesterase activity
DMR_RS02005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMR_RS02015	COG0735	belongs to the Fur family
DMR_RS02020	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DMR_RS02030	COG0058	SHG alpha-glucan phosphorylase activity
DMR_RS02035	COG0535	radical SAM domain protein
DMR_RS02060	COG0113	porphobilinogen synthase activity
DMR_RS02070	COG0535	radical SAM domain protein
DMR_RS02085	COG1131	(ABC) transporter
DMR_RS02095	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DMR_RS02110	COG0495	leucyl-tRNA aminoacylation
DMR_RS02125	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DMR_RS02130	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DMR_RS02135	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DMR_RS02135	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DMR_RS02155	COG0307	riboflavin synthase, alpha
DMR_RS02160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DMR_RS02175	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DMR_RS02180	COG1077	Cell shape determining protein MreB Mrl
DMR_RS02195	COG0768	penicillin binding
DMR_RS02200	COG0772	Belongs to the SEDS family
DMR_RS02220	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DMR_RS02225	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DMR_RS02230	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DMR_RS02275	COG1692	metallophosphoesterase
DMR_RS02290	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DMR_RS02300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DMR_RS02305	COG0438	transferase activity, transferring glycosyl groups
DMR_RS02335	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DMR_RS02345	COG0012	GTP binding
DMR_RS02405	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DMR_RS02415	COG0469	pyruvate kinase activity
DMR_RS02420	COG2095	MarC family integral membrane protein
DMR_RS02425	COG0477	Major facilitator Superfamily
DMR_RS02430	COG0704	Plays a role in the regulation of phosphate uptake
DMR_RS02440	COG2204	response regulator
DMR_RS02450	COG0159	tryptophan synthase activity
DMR_RS02455	COG0133	tryptophan synthase activity
DMR_RS02460	COG0135	phosphoribosylanthranilate isomerase activity
DMR_RS02465	COG0134	indole-3-glycerol-phosphate synthase activity
DMR_RS02470	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DMR_RS02475	COG1895	HEPN domain
DMR_RS02485	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DMR_RS02490	COG1605	Chorismate mutase
DMR_RS02490	COG0287	Prephenate dehydrogenase
DMR_RS02505	COG1465	3-dehydroquinate synthase
DMR_RS02510	COG1830	Aldolase
DMR_RS02560	COG2208	phosphoserine phosphatase activity
DMR_RS02565	COG3409	Peptidoglycan-binding domain 1 protein
DMR_RS02565	COG5632	N-Acetylmuramoyl-L-alanine amidase
DMR_RS02575	COG0840	transmembrane signaling receptor activity
DMR_RS02595	COG0363	glucosamine-6-phosphate deaminase activity
DMR_RS02600	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DMR_RS02605	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DMR_RS02620	COG3956	TIGRFAM MazG family protein
DMR_RS02625	COG1286	toxin biosynthetic process
DMR_RS02630	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DMR_RS02635	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DMR_RS02635	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DMR_RS02640	COG2131	deaminase
DMR_RS02650	COG0471	metal ion transport
DMR_RS02670	COG0784	Response regulator, receiver
DMR_RS02670	COG2205	protein histidine kinase activity
DMR_RS02675	COG4191	Histidine kinase
DMR_RS02675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DMR_RS02685	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DMR_RS02695	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DMR_RS02695	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DMR_RS02700	COG1301	dicarboxylic acid transport
DMR_RS02710	COG1053	succinate dehydrogenase
DMR_RS02715	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DMR_RS02750	COG1414	Transcriptional regulator
DMR_RS02760	COG0559	Belongs to the binding-protein-dependent transport system permease family
DMR_RS02785	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DMR_RS02825	COG2226	methyltransferase
DMR_RS02835	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DMR_RS02840	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DMR_RS02845	COG3608	succinylglutamate desuccinylase aspartoacylase
DMR_RS02845	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DMR_RS02875	COG0174	glutamine synthetase
DMR_RS02880	COG0586	Pfam SNARE associated Golgi protein
DMR_RS02890	COG1830	Aldolase
DMR_RS02905	COG0840	transmembrane signaling receptor activity
DMR_RS02915	COG0196	riboflavin kinase activity
DMR_RS02995	COG2204	response regulator
DMR_RS03010	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DMR_RS03010	COG2050	protein possibly involved in aromatic compounds catabolism
DMR_RS03055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DMR_RS03080	COG3005	denitrification pathway
DMR_RS03085	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
DMR_RS03105	COG0251	oxidation-reduction process
DMR_RS03125	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
DMR_RS03150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DMR_RS03155	COG3279	Response regulator of the LytR AlgR family
DMR_RS03160	COG2805	Type II/IV secretion system protein
DMR_RS03205	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DMR_RS03210	COG1459	type II secretion system
DMR_RS03255	COG0741	lytic transglycosylase activity
DMR_RS03260	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DMR_RS03290	COG1192	Involved in chromosome partitioning
DMR_RS03300	COG0534	Mate efflux family protein
DMR_RS03315	COG1271	oxidase subunit
DMR_RS03330	COG0784	Response regulator, receiver
DMR_RS03330	COG4191	Histidine kinase
DMR_RS03350	COG0210	DNA helicase
DMR_RS03370	COG2703	oxygen carrier activity
DMR_RS03450	COG0546	phosphoglycolate phosphatase activity
DMR_RS03485	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DMR_RS03515	COG2814	Major facilitator Superfamily
DMR_RS03535	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DMR_RS03550	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DMR_RS03550	COG0674	pyruvate-flavodoxin oxidoreductase activity
DMR_RS03580	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DMR_RS03585	COG0653	protein targeting
DMR_RS03590	COG0247	lactate metabolic process
DMR_RS03595	COG0277	FAD linked oxidase domain protein
DMR_RS03605	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DMR_RS03635	COG2226	methyltransferase
DMR_RS03675	COG2873	o-acetylhomoserine
DMR_RS03680	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DMR_RS03695	COG1346	cytolysis
DMR_RS03725	COG0840	transmembrane signaling receptor activity
DMR_RS03725	COG3290	protein histidine kinase activity
DMR_RS03730	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
DMR_RS03740	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DMR_RS03745	COG3852	Histidine kinase
DMR_RS03790	COG0784	Response regulator, receiver
DMR_RS03790	COG2205	protein histidine kinase activity
DMR_RS03795	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DMR_RS03810	COG0649	NAD binding
DMR_RS03815	COG0651	ATP synthesis coupled electron transport
DMR_RS03830	COG0651	ATP synthesis coupled electron transport
DMR_RS03835	COG0840	transmembrane signaling receptor activity
DMR_RS03840	COG2226	methyltransferase
DMR_RS03845	COG3012	SEC-C Motif Domain Protein
DMR_RS03850	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DMR_RS03885	COG1774	PSP1 C-terminal conserved region
DMR_RS03890	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DMR_RS03890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DMR_RS03895	COG0840	transmembrane signaling receptor activity
DMR_RS03910	COG0181	hydroxymethylbilane synthase activity
DMR_RS03920	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DMR_RS03925	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DMR_RS03950	COG0577	efflux transmembrane transporter activity
DMR_RS03950	COG1136	(ABC) transporter
DMR_RS03975	COG1846	Transcriptional regulator
DMR_RS03980	COG0243	molybdopterin cofactor binding
DMR_RS03985	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMR_RS03990	COG0437	4 iron, 4 sulfur cluster binding
DMR_RS04010	COG3706	GGDEF domain
DMR_RS04025	COG2814	Major facilitator Superfamily
DMR_RS04030	COG1566	PFAM secretion protein HlyD family protein
DMR_RS04040	COG1914	H( )-stimulated, divalent metal cation uptake system
DMR_RS04060	COG0840	transmembrane signaling receptor activity
DMR_RS04065	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DMR_RS04070	COG2233	PERMEase
DMR_RS04080	COG1215	transferase activity, transferring glycosyl groups
DMR_RS04095	COG3858	chitin binding
DMR_RS04105	COG1592	Rubrerythrin
DMR_RS04110	COG0450	alkyl hydroperoxide reductase
DMR_RS04120	COG0626	cystathionine gamma-synthase activity
DMR_RS04130	COG1785	Belongs to the alkaline phosphatase family
DMR_RS04170	COG0840	transmembrane signaling receptor activity
DMR_RS04185	COG5002	protein histidine kinase activity
DMR_RS04195	COG0306	phosphate transporter
DMR_RS04210	COG2208	phosphoserine phosphatase activity
DMR_RS04210	COG2770	Histidine kinase
DMR_RS04215	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DMR_RS04220	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DMR_RS04235	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DMR_RS04245	COG0702	epimerase
DMR_RS04255	COG0840	transmembrane signaling receptor activity
DMR_RS04255	COG0840	transmembrane signaling receptor activity
DMR_RS04300	COG0582	viral genome integration into host DNA
DMR_RS04335	COG3437	response regulator, receiver
DMR_RS04340	COG2201	protein-glutamate methylesterase activity
DMR_RS04375	COG2824	Alkylphosphonate utilization operon protein PhnA
DMR_RS04405	COG1022	Amp-dependent synthetase and ligase
DMR_RS04425	COG3436	PFAM IS66 Orf2 family protein
DMR_RS04430	COG4372	Transposase
DMR_RS04455	COG4372	Transposase
DMR_RS04460	COG3436	PFAM IS66 Orf2 family protein
DMR_RS04480	COG0745	RESPONSE REGULATOR receiver
DMR_RS04485	COG2205	protein histidine kinase activity
DMR_RS04490	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DMR_RS04495	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DMR_RS04500	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DMR_RS04505	COG0835	chemotaxis
DMR_RS04525	COG0582	viral genome integration into host DNA
DMR_RS04555	COG2201	protein-glutamate methylesterase activity
DMR_RS04560	COG5002	protein histidine kinase activity
DMR_RS04585	COG0582	viral genome integration into host DNA
DMR_RS04620	COG2205	protein histidine kinase activity
DMR_RS04620	COG0784	Response regulator, receiver
DMR_RS04625	COG0840	transmembrane signaling receptor activity
DMR_RS04625	COG0840	transmembrane signaling receptor activity
DMR_RS04630	COG0835	chemotaxis
DMR_RS04650	COG0582	viral genome integration into host DNA
DMR_RS04700	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DMR_RS04735	COG0784	Response regulator, receiver
DMR_RS04735	COG2198	Histidine kinase
DMR_RS04735	COG5002	protein histidine kinase activity
DMR_RS04745	COG0835	chemotaxis
DMR_RS04745	COG0784	Response regulator, receiver
DMR_RS04755	COG0840	transmembrane signaling receptor activity
DMR_RS04755	COG0840	transmembrane signaling receptor activity
DMR_RS04760	COG0835	chemotaxis
DMR_RS04785	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DMR_RS04790	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DMR_RS04795	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DMR_RS04800	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DMR_RS04805	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DMR_RS04810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DMR_RS04810	COG0072	phenylalanine-tRNA ligase activity
DMR_RS04830	COG1595	DNA-templated transcription, initiation
DMR_RS04860	COG0840	transmembrane signaling receptor activity
DMR_RS04870	COG0724	RNA recognition motif
DMR_RS04875	COG1136	(ABC) transporter
DMR_RS04875	COG0577	efflux transmembrane transporter activity
DMR_RS04895	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DMR_RS04910	COG0730	response to heat
DMR_RS04935	COG0697	spore germination
DMR_RS04950	COG2201	protein-glutamate methylesterase activity
DMR_RS04970	COG2119	membrane
DMR_RS04995	COG0303	'Molybdopterin
DMR_RS05040	COG4191	Histidine kinase
DMR_RS05055	COG5002	protein histidine kinase activity
DMR_RS05065	COG1040	competence protein
DMR_RS05075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DMR_RS05135	COG0489	protein tyrosine kinase activity
DMR_RS05160	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DMR_RS05175	COG4177	L-phenylalanine transmembrane transporter activity
DMR_RS05205	COG0586	Pfam SNARE associated Golgi protein
DMR_RS05210	COG0326	Molecular chaperone. Has ATPase activity
DMR_RS05230	COG0776	regulation of translation
DMR_RS05245	COG4977	sequence-specific DNA binding
DMR_RS05260	COG0084	hydrolase, TatD family'
DMR_RS05275	COG0784	Response regulator, receiver
DMR_RS05275	COG5002	protein histidine kinase activity
DMR_RS05275	COG2205	protein histidine kinase activity
DMR_RS05295	COG0724	RNA recognition motif
DMR_RS05310	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DMR_RS05315	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DMR_RS05320	COG0148	phosphopyruvate hydratase activity
DMR_RS05330	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DMR_RS05340	COG1136	(ABC) transporter
DMR_RS05350	COG0328	RNA-DNA hybrid ribonuclease activity
DMR_RS05375	COG0045	succinate-CoA ligase (ADP-forming) activity
DMR_RS05375	COG1042	CoA-binding domain protein
DMR_RS05375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DMR_RS05395	COG1522	sequence-specific DNA binding
DMR_RS05400	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DMR_RS05405	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DMR_RS05410	COG1797	cobyrinic acid a,c-diamide synthase activity
DMR_RS05415	COG0432	Pfam Uncharacterised protein family UPF0047
DMR_RS05440	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DMR_RS05460	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DMR_RS05465	COG3613	nucleoside 2-deoxyribosyltransferase
DMR_RS05480	COG1918	ferrous iron import across plasma membrane
DMR_RS05480	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DMR_RS05485	COG1124	(ABC) transporter
DMR_RS05490	COG0444	Belongs to the ABC transporter superfamily
DMR_RS05495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMR_RS05500	COG0601	transmembrane transport
DMR_RS05505	COG0747	negative chemotaxis
DMR_RS05510	COG0788	formyltetrahydrofolate deformylase activity
DMR_RS05525	COG4177	L-phenylalanine transmembrane transporter activity
DMR_RS05560	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DMR_RS05565	COG0049	tRNA binding
DMR_RS05570	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DMR_RS05575	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DMR_RS05580	COG0051	transcription antitermination factor activity, RNA binding
DMR_RS05585	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DMR_RS05590	COG0088	Forms part of the polypeptide exit tunnel
DMR_RS05595	COG0089	rRNA binding
DMR_RS05600	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DMR_RS05605	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DMR_RS05610	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DMR_RS05615	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DMR_RS05620	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DMR_RS05625	COG0255	Belongs to the universal ribosomal protein uL29 family
DMR_RS05630	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DMR_RS05635	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DMR_RS05640	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DMR_RS05645	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DMR_RS05650	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DMR_RS05655	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DMR_RS05665	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DMR_RS05670	COG1841	ribosomal large subunit assembly
DMR_RS05675	COG0200	Binds to the 23S rRNA
DMR_RS05690	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DMR_RS05695	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DMR_RS05700	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DMR_RS05705	COG0202	RNA polymerase activity
DMR_RS05710	COG0203	ribosomal protein L17
DMR_RS05725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DMR_RS05735	COG4662	Binding-protein-dependent transport system inner membrane component
DMR_RS05750	COG5002	protein histidine kinase activity
DMR_RS05780	COG0517	IMP dehydrogenase activity
DMR_RS05785	COG0347	Belongs to the P(II) protein family
DMR_RS05815	COG1360	Flagellar Motor Protein
DMR_RS05825	COG0439	Biotin carboxylase
DMR_RS05830	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DMR_RS05845	COG0629	single-stranded DNA binding
DMR_RS05855	COG0789	Transcriptional regulator
DMR_RS05875	COG2204	response regulator
DMR_RS05890	COG0484	heat shock protein binding
DMR_RS05895	COG0437	4 iron, 4 sulfur cluster binding
DMR_RS05895	COG3064	Membrane
DMR_RS05900	COG5557	Pfam Polysulphide reductase, NrfD
DMR_RS05905	COG2181	nitrate reductase activity
DMR_RS05910	COG0247	lactate metabolic process
DMR_RS05915	COG0589	response to stress
DMR_RS05920	COG2204	response regulator
DMR_RS05925	COG2204	response regulator
DMR_RS05935	COG0701	Predicted permease
DMR_RS05940	COG4178	(ABC) transporter
DMR_RS05955	COG0446	pyridine nucleotide-disulphide oxidoreductase
DMR_RS05965	COG4191	Histidine kinase
DMR_RS05980	COG2204	response regulator
DMR_RS05990	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DMR_RS06005	COG1132	(ABC) transporter
DMR_RS06010	COG1216	Glycosyl transferase, family 2
DMR_RS06030	COG2204	response regulator
DMR_RS06035	COG2201	protein-glutamate methylesterase activity
DMR_RS06045	COG1252	NADH dehydrogenase
DMR_RS06070	COG2205	protein histidine kinase activity
DMR_RS06075	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DMR_RS06075	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DMR_RS06130	COG1007	ATP synthesis coupled electron transport
DMR_RS06140	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DMR_RS06145	COG0713	ATP synthesis coupled electron transport
DMR_RS06155	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMR_RS06160	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DMR_RS06165	COG1034	ATP synthesis coupled electron transport
DMR_RS06180	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMR_RS06180	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMR_RS06180	COG0649	NAD binding
DMR_RS06185	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMR_RS06225	COG2200	EAL domain
DMR_RS06240	COG2089	acid synthase
DMR_RS06245	COG1127	ABC transporter
DMR_RS06280	COG2204	response regulator
DMR_RS06290	COG0492	ferredoxin-NADP+ reductase activity
DMR_RS06310	COG1490	D-aminoacyl-tRNA deacylase activity
DMR_RS06335	COG0859	PFAM glycosyl transferase family 9
DMR_RS06345	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DMR_RS06355	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DMR_RS06360	COG0571	ribonuclease III activity
DMR_RS06380	COG0583	DNA-binding transcription factor activity
DMR_RS06390	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DMR_RS06410	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DMR_RS06430	COG0823	Involved in the tonB-independent uptake of proteins
DMR_RS06435	COG2885	chlorophyll binding
DMR_RS06460	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DMR_RS06470	COG0840	transmembrane signaling receptor activity
DMR_RS06480	COG2204	response regulator
DMR_RS06520	COG0318	PFAM AMP-dependent synthetase and ligase
DMR_RS06525	COG2814	Major facilitator Superfamily
DMR_RS06535	COG0583	DNA-binding transcription factor activity
DMR_RS06590	COG2204	response regulator
DMR_RS06595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DMR_RS06595	COG4191	Histidine kinase
DMR_RS06605	COG1882	Formate acetyltransferase
DMR_RS06610	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DMR_RS06670	COG1518	maintenance of DNA repeat elements
DMR_RS06685	COG1484	DNA-dependent DNA replication
DMR_RS06690	COG4584	PFAM Integrase catalytic
DMR_RS06780	COG4974	Belongs to the 'phage' integrase family
DMR_RS06830	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DMR_RS06835	COG0594	ribonuclease P activity
DMR_RS06840	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DMR_RS06845	COG0706	membrane insertase activity
DMR_RS06850	COG1847	R3H domain protein
DMR_RS06850	COG1847	R3H domain protein
DMR_RS06855	COG0697	spore germination
DMR_RS06880	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DMR_RS06890	COG1845	cytochrome c oxidase, subunit III
DMR_RS06900	COG0109	protoheme IX farnesyltransferase activity
DMR_RS06905	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DMR_RS06935	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
DMR_RS06965	COG0582	viral genome integration into host DNA
DMR_RS06975	COG0683	leucine binding
DMR_RS06980	COG0683	leucine binding
DMR_RS06995	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DMR_RS07010	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DMR_RS07045	COG0582	viral genome integration into host DNA
DMR_RS07050	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DMR_RS07060	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DMR_RS07070	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DMR_RS07085	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DMR_RS07090	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DMR_RS07105	COG0402	S-adenosylhomocysteine deaminase activity
DMR_RS07110	COG3224	Antibiotic biosynthesis monooxygenase
DMR_RS07120	COG2271	Major facilitator Superfamily
DMR_RS07135	COG2197	response regulator
DMR_RS07140	COG0346	lactoylglutathione lyase activity
DMR_RS07145	COG1760	l-serine dehydratase
DMR_RS07160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DMR_RS07165	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DMR_RS07170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DMR_RS07175	COG4822	anaerobic cobalamin biosynthetic process
DMR_RS07240	COG1360	Flagellar Motor Protein
DMR_RS07245	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DMR_RS07255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DMR_RS07280	COG0437	4 iron, 4 sulfur cluster binding
DMR_RS07285	COG0243	molybdopterin cofactor binding
DMR_RS07285	COG3383	formate dehydrogenase (NAD+) activity
DMR_RS07290	COG0243	molybdopterin cofactor binding
DMR_RS07290	COG3383	formate dehydrogenase (NAD+) activity
DMR_RS07315	COG2205	protein histidine kinase activity
DMR_RS07325	COG0805	protein transport
DMR_RS07330	COG3158	transport of potassium into the cell
DMR_RS07350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMR_RS07360	COG2920	part of a sulfur-relay system
DMR_RS07385	COG0071	Belongs to the small heat shock protein (HSP20) family
DMR_RS07405	COG0688	phosphatidylethanolamine metabolic process
DMR_RS07410	COG1183	phosphatidylcholine synthase activity
DMR_RS07415	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DMR_RS07420	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DMR_RS07425	COG0066	3-isopropylmalate dehydratase activity
DMR_RS07430	COG0473	3-isopropylmalate dehydrogenase activity
DMR_RS07435	COG0488	(ABC) transporter
DMR_RS07440	COG0494	nUDIX hydrolase
DMR_RS07445	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DMR_RS07450	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DMR_RS07500	COG0745	RESPONSE REGULATOR receiver
DMR_RS07520	COG2204	response regulator
DMR_RS07525	COG4191	Histidine kinase
DMR_RS07530	COG0840	transmembrane signaling receptor activity
DMR_RS07535	COG0596	Alpha beta hydrolase
DMR_RS07550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DMR_RS07555	COG0543	2 iron, 2 sulfur cluster binding
DMR_RS07560	COG0167	dihydroorotate dehydrogenase activity
DMR_RS07570	COG0004	ammonium transporteR
DMR_RS07615	COG1959	2 iron, 2 sulfur cluster binding
DMR_RS07625	COG0563	adenylate kinase activity
DMR_RS07630	COG0037	tRNA processing
DMR_RS07640	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DMR_RS07645	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DMR_RS07650	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DMR_RS07650	COG1648	precorrin-2 dehydrogenase activity
DMR_RS07665	COG1749	Flagellar hook protein flgE
DMR_RS07700	COG1280	lysine exporter protein (LysE YggA)
DMR_RS07705	COG0531	amino acid
DMR_RS07710	COG1380	Effector of murein hydrolase LrgA
DMR_RS07715	COG1346	cytolysis
DMR_RS07720	COG1691	(AIR) carboxylase
DMR_RS07725	COG1606	tRNA processing
DMR_RS07730	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
DMR_RS07735	COG0667	Aldo Keto reductase
DMR_RS07740	COG2207	Transcriptional regulator
DMR_RS07770	COG0840	transmembrane signaling receptor activity
DMR_RS07780	COG1918	ferrous iron import across plasma membrane
DMR_RS07780	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DMR_RS07800	COG0442	prolyl-tRNA aminoacylation
DMR_RS07815	COG0514	ATP-dependent DNA helicase (RecQ)
DMR_RS07825	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DMR_RS07830	COG0151	Belongs to the GarS family
DMR_RS07865	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DMR_RS07875	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DMR_RS07880	COG0602	queuosine metabolic process
DMR_RS07890	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DMR_RS07900	COG5599	Phosphatase
DMR_RS07905	COG0671	phosphoesterase, PA-phosphatase related
DMR_RS07940	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DMR_RS07950	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DMR_RS07955	COG2205	protein histidine kinase activity
DMR_RS07955	COG2198	Histidine kinase
DMR_RS07955	COG0784	Response regulator, receiver
DMR_RS07960	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DMR_RS07970	COG1530	ribonuclease E activity
DMR_RS07975	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DMR_RS07980	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DMR_RS07990	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DMR_RS07995	COG0105	UTP biosynthetic process
DMR_RS08000	COG1993	acr, cog1993
DMR_RS08005	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DMR_RS08015	COG1104	cysteine desulfurase activity
DMR_RS08025	COG1045	serine acetyltransferase
DMR_RS08040	COG1659	Linocin_M18 bacteriocin protein
DMR_RS08055	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DMR_RS08060	COG1704	LemA family
DMR_RS08065	COG0613	PHP domain protein
DMR_RS08075	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DMR_RS08080	COG0114	fumarate hydratase activity
DMR_RS08090	COG3048	D-serine ammonia-lyase activity
DMR_RS08100	COG0529	Catalyzes the synthesis of activated sulfate
DMR_RS08100	COG2895	sulfate adenylyltransferase (ATP) activity
DMR_RS08120	COG0482	sulfurtransferase activity
DMR_RS08125	COG0154	amidase activity
DMR_RS08130	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DMR_RS08140	COG0443	Heat shock 70 kDa protein
DMR_RS08145	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DMR_RS08150	COG1420	regulation of RNA biosynthetic process
DMR_RS08160	COG2186	Transcriptional regulator
DMR_RS08185	COG0725	ABC transporter, periplasmic molybdate-binding protein
DMR_RS08190	COG4149	molybdate abc transporter
DMR_RS08205	COG1433	Dinitrogenase iron-molybdenum cofactor
DMR_RS08205	COG0535	radical SAM domain protein
DMR_RS08240	COG4953	penicillin-binding protein 1C
DMR_RS08245	COG0745	RESPONSE REGULATOR receiver
DMR_RS08260	COG2033	superoxide reductase activity
DMR_RS08280	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DMR_RS08285	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DMR_RS08300	COG0793	Belongs to the peptidase S41A family
DMR_RS08330	COG1032	radical SAM domain protein
DMR_RS08340	COG3852	Histidine kinase
DMR_RS08345	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DMR_RS08355	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DMR_RS08365	COG0492	ferredoxin-NADP+ reductase activity
DMR_RS08380	COG0523	cobalamin synthesis protein
DMR_RS08395	COG0589	response to stress
DMR_RS08405	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DMR_RS08410	COG0527	aspartate kinase activity
DMR_RS08415	COG0802	atpase or kinase
DMR_RS08425	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DMR_RS08425	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DMR_RS08435	COG1234	tRNA 3'-trailer cleavage
DMR_RS08445	COG0791	NLP P60 protein
DMR_RS08460	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
DMR_RS08465	COG0662	Cupin 2, conserved barrel domain protein
DMR_RS08465	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
DMR_RS08475	COG0243	molybdopterin cofactor binding
DMR_RS08480	COG0437	4 iron, 4 sulfur cluster binding
DMR_RS08485	COG5557	Pfam Polysulphide reductase, NrfD
DMR_RS08490	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DMR_RS08520	COG0306	phosphate transporter
DMR_RS08525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DMR_RS08530	COG0739	heme binding
DMR_RS08540	COG0584	glycerophosphoryl diester phosphodiesterase
DMR_RS08570	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DMR_RS08585	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DMR_RS08590	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DMR_RS08605	COG1077	Cell shape determining protein MreB Mrl
DMR_RS08610	COG0483	inositol monophosphate 1-phosphatase activity
DMR_RS08615	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DMR_RS08620	COG0456	acetyltransferase
DMR_RS08625	COG0126	phosphoglycerate kinase activity
DMR_RS08635	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DMR_RS08655	COG0210	DNA helicase
DMR_RS08700	COG3436	PFAM IS66 Orf2 family protein
DMR_RS08705	COG4372	Transposase
DMR_RS08710	COG1484	DNA-dependent DNA replication
DMR_RS08760	COG2801	Transposase and inactivated derivatives
DMR_RS08770	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DMR_RS08800	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DMR_RS08800	COG0674	pyruvate-flavodoxin oxidoreductase activity
DMR_RS08805	COG1013	pyruvate-flavodoxin oxidoreductase activity
DMR_RS08815	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DMR_RS08825	COG3850	Histidine kinase
DMR_RS08825	COG2205	protein histidine kinase activity
DMR_RS08825	COG4999	Histidine kinase
DMR_RS08825	COG3437	response regulator, receiver
DMR_RS08835	COG3437	response regulator, receiver
DMR_RS08845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DMR_RS08850	COG0730	response to heat
DMR_RS08875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DMR_RS08885	COG2204	response regulator
DMR_RS08900	COG4106	trans-aconitate 2-methyltransferase activity
DMR_RS08900	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DMR_RS08910	COG0156	8-amino-7-oxononanoate synthase activity
DMR_RS08920	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DMR_RS08925	COG1285	pathogenesis
DMR_RS08930	COG1830	Aldolase
DMR_RS08940	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DMR_RS08950	COG0745	RESPONSE REGULATOR receiver
DMR_RS08960	COG0643	Histidine kinase
DMR_RS08960	COG2198	Histidine kinase
DMR_RS08985	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DMR_RS08985	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DMR_RS09000	COG1366	Belongs to the anti-sigma-factor antagonist family
DMR_RS09020	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DMR_RS09065	COG0726	polysaccharide deacetylase
DMR_RS09075	COG1686	Belongs to the peptidase S11 family
DMR_RS09115	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DMR_RS09135	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DMR_RS09155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DMR_RS09175	COG0725	ABC transporter, periplasmic molybdate-binding protein
DMR_RS09185	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DMR_RS09200	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DMR_RS09205	COG0725	ABC transporter, periplasmic molybdate-binding protein
DMR_RS09210	COG4149	molybdate abc transporter
DMR_RS09230	COG0840	transmembrane signaling receptor activity
DMR_RS09235	COG0577	efflux transmembrane transporter activity
DMR_RS09235	COG1136	(ABC) transporter
DMR_RS09250	COG4191	Histidine kinase
DMR_RS09255	COG2204	response regulator
DMR_RS09260	COG0318	PFAM AMP-dependent synthetase and ligase
DMR_RS09275	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DMR_RS09310	COG3162	membrane
DMR_RS09315	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DMR_RS09330	COG2176	DNA-directed DNA polymerase activity
DMR_RS09335	COG0735	belongs to the Fur family
DMR_RS09340	COG1592	Rubrerythrin
DMR_RS09345	COG1773	rubredoxin
DMR_RS09355	COG2205	protein histidine kinase activity
DMR_RS09360	COG0628	permease
DMR_RS09375	COG2205	protein histidine kinase activity
DMR_RS09390	COG0577	efflux transmembrane transporter activity
DMR_RS09395	COG1136	(ABC) transporter
DMR_RS09420	COG1758	RNA polymerase activity
DMR_RS09425	COG0484	heat shock protein binding
DMR_RS09435	COG0315	cyclic pyranopterin monophosphate synthase activity
DMR_RS09440	COG1139	Iron-sulfur cluster binding protein
DMR_RS09445	COG1556	Lactate utilization protein
DMR_RS09450	COG1620	l-lactate permease
DMR_RS09455	COG1492	cobalamin metabolic process
DMR_RS09460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DMR_RS09460	COG0045	succinate-CoA ligase (ADP-forming) activity
DMR_RS09460	COG1042	CoA-binding domain protein
DMR_RS09470	COG0277	FAD linked oxidase domain protein
DMR_RS09480	COG2204	response regulator
DMR_RS09490	COG0552	protein localization to endoplasmic reticulum
DMR_RS09530	COG0017	Asparaginyl-tRNA synthetase
DMR_RS09535	COG0463	Glycosyl transferase, family 2
DMR_RS09540	COG4106	trans-aconitate 2-methyltransferase activity
DMR_RS09550	COG0297	glycogen (starch) synthase activity
DMR_RS09560	COG5001	Diguanylate cyclase
DMR_RS09565	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DMR_RS09570	COG0704	Plays a role in the regulation of phosphate uptake
DMR_RS09580	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DMR_RS09605	COG0505	Belongs to the CarA family
DMR_RS09610	COG1181	Belongs to the D-alanine--D-alanine ligase family
DMR_RS09625	COG0298	carbon dioxide binding
DMR_RS09640	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DMR_RS09645	COG1201	RNA secondary structure unwinding
DMR_RS09665	COG0745	RESPONSE REGULATOR receiver
DMR_RS09675	COG1704	LemA family
DMR_RS09685	COG0243	molybdopterin cofactor binding
DMR_RS09720	COG0347	Belongs to the P(II) protein family
DMR_RS09725	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
DMR_RS09730	COG2183	response to ionizing radiation
DMR_RS09760	COG0297	glycogen (starch) synthase activity
DMR_RS09765	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DMR_RS09780	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DMR_RS09790	COG1193	negative regulation of DNA recombination
DMR_RS09795	COG0358	DNA primase activity
DMR_RS09805	COG1671	Belongs to the UPF0178 family
DMR_RS09815	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DMR_RS09825	COG2309	aminopeptidase activity
DMR_RS09835	COG0835	chemotaxis
DMR_RS09850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DMR_RS09860	COG1381	Involved in DNA repair and RecF pathway recombination
DMR_RS09865	COG0752	glycyl-tRNA synthetase alpha subunit
DMR_RS09870	COG0751	glycine-tRNA ligase activity
DMR_RS09875	COG0268	Binds directly to 16S ribosomal RNA
DMR_RS09905	COG1132	(ABC) transporter
DMR_RS09920	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
DMR_RS09925	COG3394	polysaccharide catabolic process
DMR_RS09935	COG2198	Histidine kinase
DMR_RS09935	COG0784	Response regulator, receiver
DMR_RS09935	COG2205	protein histidine kinase activity
DMR_RS09940	COG1217	gtp-binding protein TYPA
DMR_RS09965	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DMR_RS09975	COG0107	imidazoleglycerol-phosphate synthase activity
DMR_RS09980	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DMR_RS09990	COG1494	fructose-1,6-bisphosphatase
DMR_RS10000	COG0698	ribose 5-phosphate isomerase
DMR_RS10015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DMR_RS10020	COG1410	methionine synthase
DMR_RS10020	COG0646	methionine synthase
DMR_RS10025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DMR_RS10035	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DMR_RS10065	COG0019	diaminopimelate decarboxylase activity
DMR_RS10125	COG0322	excinuclease ABC activity
DMR_RS10135	COG4895	conserved protein (DUF2196)
DMR_RS10150	COG0519	Catalyzes the synthesis of GMP from XMP
DMR_RS10155	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DMR_RS10170	COG0484	heat shock protein binding
DMR_RS10185	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DMR_RS10210	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DMR_RS10215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DMR_RS10230	COG0517	IMP dehydrogenase activity
DMR_RS10230	COG0516	GMP reductase activity
DMR_RS10235	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DMR_RS10240	COG0489	protein tyrosine kinase activity
DMR_RS10245	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DMR_RS10270	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DMR_RS10275	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DMR_RS10280	COG3118	belongs to the thioredoxin family
DMR_RS10285	COG0492	ferredoxin-NADP+ reductase activity
DMR_RS10290	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DMR_RS10300	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DMR_RS10310	COG0742	ribosomal rna small subunit methyltransferase
DMR_RS10315	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DMR_RS10320	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DMR_RS10330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DMR_RS10360	COG1872	DUF167
DMR_RS10370	COG0028	Belongs to the TPP enzyme family
DMR_RS10375	COG0440	acetolactate synthase activity
DMR_RS10380	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DMR_RS10410	COG0456	acetyltransferase
DMR_RS10420	COG0375	protein maturation
DMR_RS10425	COG1811	Na channel or pump
DMR_RS10435	COG0343	queuine tRNA-ribosyltransferase activity
DMR_RS10440	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DMR_RS10465	COG0436	Aminotransferase
DMR_RS10475	COG0617	tRNA 3'-terminal CCA addition
DMR_RS10475	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DMR_RS10475	COG3620	sequence-specific DNA binding
DMR_RS10480	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DMR_RS10485	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DMR_RS10505	COG0667	Aldo Keto reductase
DMR_RS10515	COG1846	Transcriptional regulator
DMR_RS10540	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DMR_RS10545	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DMR_RS10550	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DMR_RS10555	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DMR_RS10585	COG1122	ATPase activity
DMR_RS10590	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DMR_RS10615	COG4946	Tricorn protease homolog
DMR_RS10615	COG1506	peptidase
DMR_RS10615	COG0823	Involved in the tonB-independent uptake of proteins
DMR_RS10620	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DMR_RS10640	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DMR_RS10650	COG0131	Imidazoleglycerol-phosphate dehydratase
DMR_RS10655	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DMR_RS10660	COG0519	Catalyzes the synthesis of GMP from XMP
DMR_RS10665	COG0517	IMP dehydrogenase activity
DMR_RS10665	COG0516	GMP reductase activity
DMR_RS10700	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DMR_RS10710	COG1131	(ABC) transporter
DMR_RS10715	COG1138	Cytochrome C-type biogenesis protein
DMR_RS10720	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DMR_RS10725	COG1253	flavin adenine dinucleotide binding
DMR_RS10735	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DMR_RS10740	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DMR_RS10780	COG3829	transcription factor binding
DMR_RS10780	COG3290	protein histidine kinase activity
DMR_RS10785	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DMR_RS10795	COG0559	Belongs to the binding-protein-dependent transport system permease family
DMR_RS10820	COG0517	IMP dehydrogenase activity
DMR_RS10860	COG1028	Short-chain dehydrogenase reductase Sdr
DMR_RS10865	COG0835	chemotaxis
DMR_RS10885	COG2414	aldehyde ferredoxin oxidoreductase
DMR_RS10890	COG0166	Belongs to the GPI family
DMR_RS10895	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DMR_RS10900	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DMR_RS10920	COG0009	L-threonylcarbamoyladenylate synthase
DMR_RS10930	COG0842	Transport permease protein
DMR_RS10935	COG1131	(ABC) transporter
DMR_RS10950	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DMR_RS10965	COG2853	Lipoprotein
DMR_RS10970	COG2207	Transcriptional regulator
DMR_RS10990	COG1388	LysM domain
DMR_RS10990	COG1376	ErfK ybiS ycfS ynhG family protein
DMR_RS10995	COG0778	Nitroreductase
DMR_RS11000	COG0791	NLP P60 protein
DMR_RS11005	COG3852	Histidine kinase
DMR_RS11010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DMR_RS11010	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DMR_RS11030	COG0784	Response regulator, receiver
DMR_RS11030	COG2205	protein histidine kinase activity
DMR_RS11050	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DMR_RS11050	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DMR_RS11055	COG0215	cysteine-tRNA ligase activity
DMR_RS11065	COG0708	Exodeoxyribonuclease III
DMR_RS11080	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DMR_RS11085	COG1496	oxidoreductase activity
DMR_RS11095	COG1090	epimerase
DMR_RS11105	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DMR_RS11120	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DMR_RS11125	COG0018	arginyl-trna synthetase
DMR_RS11135	COG1945	arginine decarboxylase activity
DMR_RS11140	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DMR_RS11170	COG1187	pseudouridine synthase activity
DMR_RS11185	COG0719	Fe-S assembly protein
DMR_RS11195	COG2204	response regulator
DMR_RS11200	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DMR_RS11240	COG1331	Highly conserved protein containing a thioredoxin domain
DMR_RS11250	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
DMR_RS11275	COG0564	pseudouridine synthase activity
DMR_RS11285	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DMR_RS11295	COG2985	domain, Protein
DMR_RS11300	COG0556	nucleotide-excision repair
DMR_RS11320	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DMR_RS11325	COG0542	response to heat
DMR_RS11330	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DMR_RS11340	COG2201	protein-glutamate methylesterase activity
DMR_RS11345	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DMR_RS11350	COG0835	chemotaxis
DMR_RS11355	COG2198	Histidine kinase
DMR_RS11355	COG0643	Histidine kinase
DMR_RS11370	COG3852	Histidine kinase
DMR_RS11375	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DMR_RS11380	COG1639	'signal transduction protein
DMR_RS11385	COG0037	tRNA processing
DMR_RS11395	COG1684	flagellar biosynthetic protein fliR
DMR_RS11400	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DMR_RS11405	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DMR_RS11410	COG1419	protein localization to endoplasmic reticulum
DMR_RS11420	COG1191	sigma factor activity
DMR_RS11450	COG1674	ftsk spoiiie
DMR_RS11450	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DMR_RS11455	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DMR_RS11460	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DMR_RS11465	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DMR_RS11475	COG1968	undecaprenyl-diphosphatase activity
DMR_RS11535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DMR_RS11555	COG0535	radical SAM domain protein
DMR_RS11560	COG1192	Involved in chromosome partitioning
DMR_RS11580	COG1011	Hydrolase
DMR_RS11615	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DMR_RS11620	COG0778	Nitroreductase
DMR_RS11625	COG0142	geranyltranstransferase activity
DMR_RS11630	COG1722	exodeoxyribonuclease VII activity
DMR_RS11635	COG1570	exodeoxyribonuclease VII activity
DMR_RS11640	COG0442	prolyl-tRNA aminoacylation
DMR_RS11645	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DMR_RS11670	COG3852	Histidine kinase
DMR_RS11700	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DMR_RS11705	COG0746	molybdenum cofactor guanylyltransferase activity
DMR_RS11710	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DMR_RS11720	COG2985	domain, Protein
DMR_RS11720	COG0569	domain protein
DMR_RS11725	COG4783	chaperone-mediated protein folding
DMR_RS11740	COG1083	cytidylyl-transferase
DMR_RS11745	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DMR_RS11750	COG0641	radical SAM
DMR_RS11755	COG2089	acid synthase
DMR_RS11765	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DMR_RS11805	COG4974	Belongs to the 'phage' integrase family
DMR_RS11975	COG3621	Patatin-like phospholipase
DMR_RS12030	COG0305	Participates in initiation and elongation during chromosome replication
DMR_RS12045	COG1396	sequence-specific DNA binding
DMR_RS12045	COG3800	Transcriptional regulator
DMR_RS12055	COG1598	PFAM Uncharacterised protein family UPF0150
DMR_RS12065	COG0351	phosphomethylpyrimidine kinase
DMR_RS12075	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DMR_RS12080	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DMR_RS12085	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DMR_RS12110	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DMR_RS12135	COG0750	zinc metalloprotease
DMR_RS12145	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DMR_RS12150	COG0799	negative regulation of ribosome biogenesis
DMR_RS12155	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DMR_RS12170	COG2198	Histidine kinase
DMR_RS12170	COG0784	Response regulator, receiver
DMR_RS12170	COG2205	protein histidine kinase activity
DMR_RS12175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DMR_RS12180	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DMR_RS12190	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DMR_RS12230	COG0859	PFAM glycosyl transferase family 9
DMR_RS12240	COG1472	Belongs to the glycosyl hydrolase 3 family
DMR_RS12245	COG0840	transmembrane signaling receptor activity
DMR_RS12245	COG3290	protein histidine kinase activity
DMR_RS12275	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DMR_RS12280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DMR_RS12290	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DMR_RS12295	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DMR_RS12300	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DMR_RS12305	COG0745	RESPONSE REGULATOR receiver
DMR_RS12320	COG1151	hydroxylamine reductase activity
DMR_RS12330	COG1227	inorganic diphosphatase activity
DMR_RS12345	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DMR_RS12360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DMR_RS12370	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DMR_RS12375	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DMR_RS12380	COG0504	CTP synthase activity
DMR_RS12385	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DMR_RS12385	COG0047	phosphoribosylformylglycinamidine synthase activity
DMR_RS12390	COG0590	tRNA wobble adenosine to inosine editing
DMR_RS12400	COG1032	radical SAM domain protein
DMR_RS12405	COG2855	membrane
DMR_RS12425	COG0277	FAD linked oxidase domain protein
DMR_RS12430	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DMR_RS12435	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DMR_RS12440	COG0402	S-adenosylhomocysteine deaminase activity
DMR_RS12450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DMR_RS12455	COG2226	methyltransferase
DMR_RS12470	COG4535	Mg2 and Co2 transporter CorC
DMR_RS12475	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DMR_RS12480	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DMR_RS12485	COG3706	GGDEF domain
DMR_RS12495	COG0776	regulation of translation
DMR_RS12515	COG1215	transferase activity, transferring glycosyl groups
DMR_RS12545	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DMR_RS12550	COG0432	Pfam Uncharacterised protein family UPF0047
DMR_RS12560	COG3961	Belongs to the TPP enzyme family
DMR_RS12565	COG0784	Response regulator, receiver
DMR_RS12565	COG2205	protein histidine kinase activity
DMR_RS12600	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DMR_RS12635	COG1942	4-Oxalocrotonate Tautomerase
DMR_RS12640	COG2249	NAD(P)H dehydrogenase (quinone) activity
DMR_RS12645	COG3655	Transcriptional regulator
DMR_RS12670	COG0539	negative regulation of cytoplasmic translation
DMR_RS12675	COG0488	(ABC) transporter
DMR_RS12680	COG0840	transmembrane signaling receptor activity
DMR_RS12695	COG0137	argininosuccinate synthase activity
DMR_RS12735	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DMR_RS12740	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DMR_RS12745	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DMR_RS12750	COG0835	chemotaxis
DMR_RS12750	COG0784	Response regulator, receiver
DMR_RS12800	COG1305	Transglutaminase-like
DMR_RS12815	COG1032	radical SAM domain protein
DMR_RS12825	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DMR_RS12840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DMR_RS12845	COG1121	(ABC) transporter
DMR_RS12850	COG3443	Belongs to the bacterial solute-binding protein 9 family
DMR_RS12850	COG0803	Belongs to the bacterial solute-binding protein 9 family
DMR_RS12870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DMR_RS12895	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DMR_RS12900	COG0778	Nitroreductase
DMR_RS12920	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DMR_RS12930	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DMR_RS12935	COG0305	Participates in initiation and elongation during chromosome replication
DMR_RS12940	COG0359	binds to the 23S rRNA
DMR_RS12945	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DMR_RS12950	COG0360	Binds together with S18 to 16S ribosomal RNA
DMR_RS12970	COG0330	HflC and HflK could
DMR_RS12975	COG0330	HflC and HflK could
DMR_RS12995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMR_RS13000	COG1136	(ABC) transporter
DMR_RS13000	COG0577	efflux transmembrane transporter activity
DMR_RS13005	COG1136	(ABC) transporter
DMR_RS13005	COG0577	efflux transmembrane transporter activity
DMR_RS13010	COG4372	Transposase
DMR_RS13015	COG3436	PFAM IS66 Orf2 family protein
DMR_RS13025	COG0835	chemotaxis
DMR_RS13045	COG3385	transposase activity
DMR_RS13055	COG5002	protein histidine kinase activity
DMR_RS13070	COG1639	'signal transduction protein
DMR_RS13115	COG0210	DNA helicase
DMR_RS13125	COG4372	Transposase
DMR_RS13130	COG3436	PFAM IS66 Orf2 family protein
DMR_RS13145	COG0840	transmembrane signaling receptor activity
DMR_RS13145	COG0840	transmembrane signaling receptor activity
DMR_RS13160	COG1595	DNA-templated transcription, initiation
DMR_RS13165	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DMR_RS13175	COG1139	Iron-sulfur cluster binding protein
DMR_RS13180	COG0247	lactate metabolic process
DMR_RS13190	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
DMR_RS13190	COG3264	Mechanosensitive ion channel
DMR_RS13215	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DMR_RS13220	COG0736	holo-[acyl-carrier-protein] synthase activity
DMR_RS13230	COG0667	Aldo Keto reductase
DMR_RS13235	COG0348	domain, Protein
DMR_RS13235	COG3901	Regulator of nitric oxide reductase transcription
DMR_RS13260	COG4206	TonB-dependent receptor
DMR_RS13270	COG1122	ATPase activity
DMR_RS13295	COG2390	Transcriptional regulator
DMR_RS13300	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DMR_RS13305	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DMR_RS13310	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DMR_RS13330	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DMR_RS13335	COG0649	NAD binding
DMR_RS13340	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMR_RS13340	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMR_RS13340	COG0649	NAD binding
DMR_RS13345	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMR_RS13350	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMR_RS13355	COG1007	ATP synthesis coupled electron transport
DMR_RS13365	COG0651	ATP synthesis coupled electron transport
DMR_RS13375	COG0651	ATP synthesis coupled electron transport
DMR_RS13380	COG0713	ATP synthesis coupled electron transport
DMR_RS13405	COG2814	Major facilitator Superfamily
DMR_RS13415	COG0436	Aminotransferase
DMR_RS13435	COG0835	chemotaxis
DMR_RS13435	COG0784	Response regulator, receiver
DMR_RS13440	COG4651	solute:proton antiporter activity
DMR_RS13440	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DMR_RS13460	COG2423	ornithine cyclodeaminase activity
DMR_RS13470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMR_RS13480	COG3264	Mechanosensitive ion channel
DMR_RS13480	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
DMR_RS13495	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DMR_RS13520	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DMR_RS13530	COG0740	serine-type endopeptidase activity
DMR_RS13535	COG0544	peptidyl-prolyl cis-trans isomerase activity
DMR_RS13555	COG0538	isocitrate dehydrogenase activity
DMR_RS13570	COG1388	LysM domain
DMR_RS13570	COG3584	3D domain protein
DMR_RS13575	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DMR_RS13585	COG2816	NAD+ diphosphatase activity
DMR_RS13595	COG1271	oxidase subunit
DMR_RS13600	COG1294	oxidase, subunit
DMR_RS13635	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DMR_RS13640	COG1309	transcriptional regulator
DMR_RS13675	COG1459	type II secretion system
DMR_RS13685	COG4970	Tfp pilus assembly protein FimT
DMR_RS13725	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DMR_RS13730	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DMR_RS13775	COG1584	GPR1 FUN34 yaaH family protein
DMR_RS13780	COG3706	GGDEF domain
DMR_RS13790	COG2201	protein-glutamate methylesterase activity
DMR_RS13800	COG2198	Histidine kinase
DMR_RS13800	COG0643	Histidine kinase
DMR_RS13820	COG2308	Evidence 4 Homologs of previously reported genes of
DMR_RS13830	COG3852	Histidine kinase
DMR_RS13835	COG1846	Transcriptional regulator
DMR_RS13870	COG1702	phosphate starvation-inducible protein PhoH
DMR_RS13875	COG1480	7TM receptor with intracellular HD hydrolase
DMR_RS13880	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DMR_RS13895	COG2078	PFAM AMMECR1 domain protein
DMR_RS13910	COG0861	Integral membrane protein TerC family
DMR_RS13925	COG0840	transmembrane signaling receptor activity
DMR_RS13940	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
DMR_RS13950	COG0436	Aminotransferase
DMR_RS13965	COG1484	DNA-dependent DNA replication
DMR_RS13970	COG4584	PFAM Integrase catalytic
DMR_RS13975	COG2205	protein histidine kinase activity
DMR_RS13975	COG0784	Response regulator, receiver
DMR_RS14020	COG0840	transmembrane signaling receptor activity
DMR_RS14050	COG4585	Histidine kinase
DMR_RS14055	COG2414	aldehyde ferredoxin oxidoreductase
DMR_RS14095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMR_RS14100	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DMR_RS14110	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DMR_RS14115	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DMR_RS14120	COG0193	aminoacyl-tRNA hydrolase activity
DMR_RS14130	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DMR_RS14135	COG4783	chaperone-mediated protein folding
DMR_RS14150	COG2373	Large extracellular alpha-helical protein
DMR_RS14155	COG2805	Type II/IV secretion system protein
DMR_RS14180	COG0023	Translation Initiation Factor
DMR_RS14225	COG0784	Response regulator, receiver
DMR_RS14225	COG5002	protein histidine kinase activity
DMR_RS14225	COG2205	protein histidine kinase activity
DMR_RS14240	COG0471	metal ion transport
DMR_RS14255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DMR_RS14260	COG0437	4 iron, 4 sulfur cluster binding
DMR_RS14265	COG2414	aldehyde ferredoxin oxidoreductase
DMR_RS14275	COG0443	Heat shock 70 kDa protein
DMR_RS14290	COG1309	transcriptional regulator
DMR_RS14295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMR_RS14310	COG3436	PFAM IS66 Orf2 family protein
DMR_RS14315	COG4372	Transposase
DMR_RS14320	COG0840	transmembrane signaling receptor activity
DMR_RS14330	COG0840	transmembrane signaling receptor activity
DMR_RS14330	COG0840	transmembrane signaling receptor activity
DMR_RS14340	COG0835	chemotaxis
DMR_RS14340	COG0784	Response regulator, receiver
DMR_RS14375	COG2365	Tyrosine phosphatase family
DMR_RS14445	COG0582	viral genome integration into host DNA
DMR_RS14450	COG0582	viral genome integration into host DNA
DMR_RS14525	COG0582	viral genome integration into host DNA
DMR_RS14555	COG0285	dihydrofolate synthase activity
DMR_RS14560	COG1921	L-seryl-tRNASec selenium transferase activity
DMR_RS14570	COG1362	aminopeptidase activity
DMR_RS14580	COG0180	Tryptophanyl-tRNA synthetase
DMR_RS14585	COG1994	Peptidase M50
DMR_RS14600	COG0037	tRNA processing
DMR_RS14615	COG1216	Glycosyl transferase, family 2
DMR_RS14625	COG0542	response to heat
DMR_RS14630	COG0789	Transcriptional regulator
DMR_RS14650	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DMR_RS14655	COG2226	methyltransferase
DMR_RS14670	COG0352	thiamine-phosphate diphosphorylase activity
DMR_RS14675	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DMR_RS14680	COG5002	protein histidine kinase activity
DMR_RS14680	COG0784	Response regulator, receiver
DMR_RS14680	COG2205	protein histidine kinase activity
DMR_RS14690	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DMR_RS14695	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
DMR_RS14700	COG2255	four-way junction helicase activity
DMR_RS14705	COG0632	four-way junction helicase activity
DMR_RS14710	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DMR_RS14715	COG0217	transcriptional regulatory protein
DMR_RS14720	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DMR_RS14755	COG0628	permease
DMR_RS14770	COG0765	amino acid transport
DMR_RS14820	COG1126	abc transporter atp-binding protein
DMR_RS14830	COG0277	FAD linked oxidase domain protein
DMR_RS14845	COG3706	GGDEF domain
DMR_RS14850	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DMR_RS14850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DMR_RS14860	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DMR_RS14870	COG3706	GGDEF domain
DMR_RS14875	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DMR_RS14880	COG0085	RNA polymerase activity
DMR_RS14885	COG0222	ribosome binding
DMR_RS14890	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DMR_RS14895	COG0081	regulation of translation
DMR_RS14900	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DMR_RS14910	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DMR_RS14925	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DMR_RS14950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DMR_RS14960	COG2890	protein-(glutamine-N5) methyltransferase activity
DMR_RS14965	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DMR_RS14970	COG3872	metal-dependent enzyme
DMR_RS14975	COG0254	rRNA binding
DMR_RS14980	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DMR_RS14985	COG0588	phosphoglycerate mutase activity
DMR_RS14990	COG1160	GTP binding
DMR_RS15025	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DMR_RS15030	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DMR_RS15035	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
DMR_RS15045	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DMR_RS15060	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
DMR_RS15065	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DMR_RS15075	COG1256	bacterial-type flagellum assembly
DMR_RS15085	COG0739	heme binding
DMR_RS15090	COG1706	bacterial-type flagellum-dependent cell motility
DMR_RS15095	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DMR_RS15105	COG4786	Flagellar basal body rod
DMR_RS15110	COG4786	Flagellar basal body rod
DMR_RS15125	COG0195	Participates in both transcription termination and antitermination
DMR_RS15130	COG3266	domain, Protein
DMR_RS15130	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DMR_RS15150	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DMR_RS15155	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DMR_RS15170	COG1355	regulation of microtubule-based process
DMR_RS15205	COG1469	GTP cyclohydrolase I activity
DMR_RS15210	COG0864	Transcriptional regulator
DMR_RS15220	COG0509	glycine decarboxylation via glycine cleavage system
DMR_RS15225	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DMR_RS15230	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DMR_RS15235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DMR_RS15245	COG0424	maF-like protein
DMR_RS15335	COG4974	Belongs to the 'phage' integrase family
DMR_RS15340	COG0582	viral genome integration into host DNA
DMR_RS15375	COG1396	sequence-specific DNA binding
DMR_RS15390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DMR_RS15405	COG4957	zinc ion binding
DMR_RS15425	COG4957	zinc ion binding
DMR_RS15435	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DMR_RS15445	COG1561	YicC-like family, N-terminal region
DMR_RS15450	COG2052	Domain of unknown function (DUF370)
DMR_RS15455	COG0194	GDP metabolic process
DMR_RS15480	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DMR_RS15480	COG3008	intermembrane lipid transfer
DMR_RS15490	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DMR_RS15505	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DMR_RS15510	COG3279	Response regulator of the LytR AlgR family
DMR_RS15515	COG3275	phosphorelay sensor kinase activity
DMR_RS15520	COG1966	Carbon starvation protein
DMR_RS15545	COG0704	Plays a role in the regulation of phosphate uptake
DMR_RS15550	COG0560	Phosphoserine phosphatase
DMR_RS15550	COG3830	Belongs to the UPF0237 family
DMR_RS15575	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DMR_RS15580	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DMR_RS15585	COG0277	FAD linked oxidase domain protein
DMR_RS15590	COG0668	transmembrane transport
DMR_RS15605	COG2855	membrane
DMR_RS15610	COG0589	response to stress
DMR_RS15620	COG2204	response regulator
DMR_RS15625	COG1280	lysine exporter protein (LysE YggA)
DMR_RS15635	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DMR_RS15645	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DMR_RS15650	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DMR_RS15655	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DMR_RS15660	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DMR_RS15665	COG0772	Belongs to the SEDS family
DMR_RS15670	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DMR_RS15675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DMR_RS15680	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DMR_RS15685	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DMR_RS15690	COG0768	penicillin binding
DMR_RS15700	COG0275	rRNA processing
DMR_RS15705	COG2001	Belongs to the MraZ family
DMR_RS15735	COG2198	Histidine kinase
DMR_RS15735	COG0784	Response regulator, receiver
DMR_RS15735	COG0643	Histidine kinase
DMR_RS15735	COG0643	Histidine kinase
DMR_RS15735	COG0784	Response regulator, receiver
DMR_RS15735	COG2198	Histidine kinase
DMR_RS15740	COG0745	RESPONSE REGULATOR receiver
DMR_RS15745	COG0835	chemotaxis
DMR_RS15750	COG1192	Involved in chromosome partitioning
DMR_RS15755	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DMR_RS15765	COG2201	protein-glutamate methylesterase activity
DMR_RS15790	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DMR_RS15800	COG0163	prenyltransferase activity
DMR_RS15805	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DMR_RS15810	COG0163	prenyltransferase activity
DMR_RS15855	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DMR_RS15860	COG2081	HI0933 family
DMR_RS15880	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DMR_RS15885	COG0741	lytic transglycosylase activity
DMR_RS15955	COG4964	Belongs to the GSP D family
DMR_RS15965	COG2204	response regulator
DMR_RS16020	COG0564	pseudouridine synthase activity
DMR_RS16025	COG1074	ATP-dependent DNA helicase activity
DMR_RS16045	COG4974	Belongs to the 'phage' integrase family
DMR_RS16065	COG0758	DNA mediated transformation
DMR_RS16090	COG1309	transcriptional regulator
DMR_RS16095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMR_RS16100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DMR_RS16110	COG5002	protein histidine kinase activity
DMR_RS16120	COG0028	Belongs to the TPP enzyme family
DMR_RS16140	COG0753	catalase activity
DMR_RS16150	COG3045	CreA protein
DMR_RS16160	COG1301	dicarboxylic acid transport
DMR_RS16170	COG1053	succinate dehydrogenase
DMR_RS16175	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DMR_RS16180	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DMR_RS16185	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DMR_RS16190	COG0543	2 iron, 2 sulfur cluster binding
DMR_RS16195	COG0493	'glutamate synthase
DMR_RS16200	COG0280	phosphate acetyltransferase
DMR_RS16200	COG0281	malic enzyme
DMR_RS16215	COG4957	zinc ion binding
DMR_RS16220	COG0110	maltose O-acetyltransferase activity
DMR_RS16240	COG1032	radical SAM domain protein
DMR_RS16250	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DMR_RS16375	COG0792	nuclease activity
DMR_RS16380	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DMR_RS16385	COG0335	large ribosomal subunit rRNA binding
DMR_RS16390	COG0336	Belongs to the RNA methyltransferase TrmD family
DMR_RS16390	COG4752	Belongs to the RNA methyltransferase TrmD family
DMR_RS16400	COG1837	Belongs to the UPF0109 family
DMR_RS16405	COG0228	four-way junction DNA binding
DMR_RS16410	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DMR_RS16415	COG0724	RNA recognition motif
DMR_RS16425	COG0436	Aminotransferase
DMR_RS16430	COG0826	peptidase U32
DMR_RS16435	COG0406	alpha-ribazole phosphatase activity
DMR_RS16455	COG1902	pentaerythritol trinitrate reductase activity
DMR_RS16470	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DMR_RS16485	COG0450	alkyl hydroperoxide reductase
DMR_RS16490	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DMR_RS16495	COG0347	Belongs to the P(II) protein family
DMR_RS16500	COG0004	ammonium transporteR
DMR_RS16505	COG0745	RESPONSE REGULATOR receiver
DMR_RS16525	COG2205	protein histidine kinase activity
DMR_RS16525	COG2198	Histidine kinase
DMR_RS16525	COG0784	Response regulator, receiver
DMR_RS16530	COG0438	transferase activity, transferring glycosyl groups
DMR_RS16555	COG2084	Dehydrogenase
DMR_RS16560	COG3622	Belongs to the hyi family
DMR_RS16570	COG4999	Histidine kinase
DMR_RS16570	COG2205	protein histidine kinase activity
DMR_RS16570	COG3437	response regulator, receiver
DMR_RS16570	COG3850	Histidine kinase
DMR_RS16585	COG0714	Associated with various cellular activities
DMR_RS16620	COG2304	oxidoreductase activity
DMR_RS16625	COG2304	oxidoreductase activity
DMR_RS16675	COG1733	regulation of RNA biosynthetic process
DMR_RS16690	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DMR_RS16730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DMR_RS16740	COG1151	hydroxylamine reductase activity
DMR_RS16775	COG1216	Glycosyl transferase, family 2
DMR_RS16820	COG0205	6-phosphofructokinase activity
DMR_RS16830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DMR_RS16835	COG1366	Belongs to the anti-sigma-factor antagonist family
DMR_RS16845	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
DMR_RS16850	COG2376	Dihydroxyacetone kinase
DMR_RS16855	COG1461	Dihydroxyacetone kinase
DMR_RS16860	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DMR_RS16860	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DMR_RS16875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DMR_RS16880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMR_RS16905	COG1196	nuclear chromosome segregation
DMR_RS16905	COG3264	Mechanosensitive ion channel
DMR_RS16940	COG2226	methyltransferase
DMR_RS16960	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DMR_RS16965	COG0142	geranyltranstransferase activity
DMR_RS16970	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DMR_RS16980	COG0840	transmembrane signaling receptor activity
DMR_RS16985	COG1773	rubredoxin
DMR_RS17040	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DMR_RS17050	COG2226	methyltransferase
DMR_RS17190	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DMR_RS17200	COG5001	Diguanylate cyclase
DMR_RS17200	COG4251	negative regulation of phosphorylation
DMR_RS17200	COG3706	GGDEF domain
DMR_RS17200	COG2203	Gaf domain
DMR_RS17205	COG5499	transcription regulator containing HTH domain
DMR_RS17215	COG4294	response to UV
DMR_RS17225	COG0745	RESPONSE REGULATOR receiver
DMR_RS17230	COG2703	oxygen carrier activity
DMR_RS17250	COG3437	response regulator, receiver
DMR_RS17260	COG0784	Response regulator, receiver
DMR_RS17260	COG2205	protein histidine kinase activity
DMR_RS17260	COG5002	protein histidine kinase activity
DMR_RS17340	COG1045	serine acetyltransferase
DMR_RS17345	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DMR_RS17345	COG3608	succinylglutamate desuccinylase aspartoacylase
DMR_RS17350	COG1104	cysteine desulfurase activity
DMR_RS17355	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DMR_RS17365	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DMR_RS17370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DMR_RS17375	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DMR_RS17380	COG1116	anion transmembrane transporter activity
DMR_RS17385	COG0626	cystathionine gamma-synthase activity
DMR_RS17390	COG0626	cystathionine gamma-synthase activity
DMR_RS17395	COG1959	2 iron, 2 sulfur cluster binding
DMR_RS17430	COG3848	Pyruvate phosphate dikinase
DMR_RS17430	COG0574	Belongs to the PEP-utilizing enzyme family
DMR_RS17435	COG2059	Chromate
DMR_RS17440	COG3678	ATP-independent chaperone mediated protein folding
DMR_RS17445	COG2226	methyltransferase
DMR_RS17450	COG1595	DNA-templated transcription, initiation
DMR_RS17455	COG0589	response to stress
DMR_RS17475	COG0640	Transcriptional regulator
DMR_RS17480	COG0798	PFAM Bile acid sodium symporter
DMR_RS17555	COG2203	Gaf domain
DMR_RS17555	COG3706	GGDEF domain
DMR_RS17555	COG5001	Diguanylate cyclase
DMR_RS17555	COG4251	negative regulation of phosphorylation
DMR_RS17560	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DMR_RS17605	COG2274	protein secretion by the type I secretion system
DMR_RS17645	COG2204	response regulator
DMR_RS17650	COG2204	response regulator
DMR_RS17655	COG0492	ferredoxin-NADP+ reductase activity
DMR_RS17685	COG0557	exoribonuclease II activity
DMR_RS17700	COG2205	protein histidine kinase activity
DMR_RS17700	COG0784	Response regulator, receiver
DMR_RS17715	COG0745	RESPONSE REGULATOR receiver
DMR_RS17730	COG1733	regulation of RNA biosynthetic process
DMR_RS17750	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DMR_RS17755	COG0233	cytoplasmic translational termination
DMR_RS17760	COG0528	UMP kinase activity
DMR_RS17765	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DMR_RS17770	COG0052	Belongs to the universal ribosomal protein uS2 family
DMR_RS17775	COG0179	Fumarylacetoacetate (FAA) hydrolase
DMR_RS17780	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DMR_RS17810	COG1083	cytidylyl-transferase
DMR_RS17815	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DMR_RS17835	COG2132	Multicopper oxidase
DMR_RS17845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DMR_RS17850	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DMR_RS17865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMR_RS17875	COG1215	transferase activity, transferring glycosyl groups
DMR_RS17890	COG0463	Glycosyl transferase, family 2
DMR_RS17900	COG2264	protein methyltransferase activity
DMR_RS17915	COG1388	LysM domain
DMR_RS17915	COG1705	Flagellar rod assembly protein muramidase FlgJ
DMR_RS17920	COG1696	Membrane protein involved in D-alanine export
DMR_RS17955	COG0840	transmembrane signaling receptor activity
DMR_RS17970	COG1842	Phage shock protein A
DMR_RS17975	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DMR_RS17980	COG0612	Peptidase, M16
DMR_RS17985	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DMR_RS17990	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DMR_RS17995	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DMR_RS18000	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DMR_RS18010	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DMR_RS18040	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DMR_RS18045	COG2197	response regulator
DMR_RS18065	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DMR_RS18075	COG1136	(ABC) transporter
DMR_RS18080	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DMR_RS18100	COG1342	Belongs to the UPF0251 family
DMR_RS18115	COG3604	Transcriptional regulator
DMR_RS18130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DMR_RS18165	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
DMR_RS18190	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
DMR_RS18205	COG1639	'signal transduction protein
DMR_RS18210	COG5002	protein histidine kinase activity
DMR_RS18215	COG1959	2 iron, 2 sulfur cluster binding
DMR_RS18220	COG2204	response regulator
DMR_RS18225	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DMR_RS18235	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DMR_RS18240	COG0581	inorganic phosphate transmembrane transporter activity
DMR_RS18245	COG0573	inorganic phosphate transmembrane transporter activity
DMR_RS18250	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DMR_RS18255	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DMR_RS18270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMR_RS18300	COG0564	pseudouridine synthase activity
DMR_RS18305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DMR_RS18310	COG3942	CHAP domain
DMR_RS18310	COG1388	LysM domain
DMR_RS18315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DMR_RS18320	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DMR_RS18325	COG0778	Nitroreductase
DMR_RS18335	COG5002	protein histidine kinase activity
DMR_RS18385	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DMR_RS18390	COG0521	Mo-molybdopterin cofactor biosynthetic process
DMR_RS18410	COG2264	protein methyltransferase activity
DMR_RS18425	COG0598	Magnesium transport protein CorA
DMR_RS18430	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DMR_RS18440	COG0589	response to stress
DMR_RS18470	COG1846	Transcriptional regulator
DMR_RS18480	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DMR_RS18495	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DMR_RS18520	COG1012	belongs to the aldehyde dehydrogenase family
DMR_RS18535	COG3180	Ammonia monooxygenase
DMR_RS18540	COG0681	Belongs to the peptidase S26 family
DMR_RS18545	COG0481	GTPase activity
DMR_RS18550	COG2046	Belongs to the sulfate adenylyltransferase family
DMR_RS18555	COG0640	Transcriptional regulator
DMR_RS18590	COG0110	maltose O-acetyltransferase activity
DMR_RS18640	COG0494	nUDIX hydrolase
DMR_RS18645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMR_RS18655	COG2835	tetraacyldisaccharide 4'-kinase activity
DMR_RS18665	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DMR_RS18670	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DMR_RS18675	COG1360	Flagellar Motor Protein
DMR_RS18680	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DMR_RS18685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DMR_RS18685	COG2205	protein histidine kinase activity
DMR_RS18695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DMR_RS18705	COG0765	amino acid transport
DMR_RS18720	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DMR_RS18725	COG3481	metal-dependent phosphohydrolase, HD sub domain
DMR_RS18730	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DMR_RS18745	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DMR_RS18760	COG1253	flavin adenine dinucleotide binding
DMR_RS18770	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DMR_RS18780	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DMR_RS18800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DMR_RS18805	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DMR_RS18820	COG1733	regulation of RNA biosynthetic process
DMR_RS18825	COG0702	epimerase
DMR_RS18835	COG4191	Histidine kinase
DMR_RS18835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DMR_RS18840	COG2204	response regulator
DMR_RS18850	COG0745	RESPONSE REGULATOR receiver
DMR_RS18880	COG2204	response regulator
DMR_RS18945	COG1086	Polysaccharide biosynthesis protein
DMR_RS18950	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DMR_RS18955	COG1215	transferase activity, transferring glycosyl groups
DMR_RS18955	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DMR_RS18980	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DMR_RS18985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMR_RS18990	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DMR_RS18995	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DMR_RS19000	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DMR_RS19020	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DMR_RS19025	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DMR_RS19035	COG2089	acid synthase
DMR_RS19040	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
DMR_RS19075	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
DMR_RS19085	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DMR_RS19110	COG1309	transcriptional regulator
DMR_RS19160	COG4372	Transposase
DMR_RS19165	COG3436	PFAM IS66 Orf2 family protein
DMR_RS19190	COG0745	RESPONSE REGULATOR receiver
DMR_RS19195	COG0745	RESPONSE REGULATOR receiver
DMR_RS19210	COG3158	transport of potassium into the cell
DMR_RS19280	COG1077	Cell shape determining protein MreB Mrl
DMR_RS19320	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DMR_RS19335	COG0348	domain, Protein
DMR_RS19335	COG3901	Regulator of nitric oxide reductase transcription
DMR_RS19355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMR_RS19425	COG3829	transcription factor binding
DMR_RS19450	COG0730	response to heat
DMR_RS19495	COG4372	Transposase
DMR_RS19500	COG3436	PFAM IS66 Orf2 family protein
DMR_RS19530	COG0835	chemotaxis
DMR_RS19560	COG4372	Transposase
DMR_RS19565	COG3436	PFAM IS66 Orf2 family protein
DMR_RS19605	COG3328	transposase activity
DMR_RS19620	COG0210	DNA helicase
DMR_RS19695	COG0210	DNA helicase
DMR_RS19775	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DMR_RS19780	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DMR_RS19790	COG0101	tRNA pseudouridine synthase activity
DMR_RS19805	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DMR_RS19830	COG0356	it plays a direct role in the translocation of protons across the membrane
DMR_RS19840	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DMR_RS19845	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DMR_RS19860	COG0589	response to stress
DMR_RS19870	COG0730	response to heat
DMR_RS19905	COG1595	DNA-templated transcription, initiation
DMR_RS19915	COG1830	Aldolase
DMR_RS19925	COG0791	NLP P60 protein
DMR_RS19940	COG0517	IMP dehydrogenase activity
DMR_RS19980	COG0784	Response regulator, receiver
DMR_RS19980	COG2205	protein histidine kinase activity
DMR_RS20000	COG0247	lactate metabolic process
DMR_RS20005	COG2181	nitrate reductase activity
DMR_RS20015	COG0741	lytic transglycosylase activity
DMR_RS20035	COG1914	H( )-stimulated, divalent metal cation uptake system
DMR_RS20050	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
DMR_RS20060	COG1607	acyl-coa hydrolase
DMR_RS20120	COG0367	asparagine synthase
DMR_RS20140	COG0463	Glycosyl transferase, family 2
DMR_RS20165	COG1136	(ABC) transporter
DMR_RS20170	COG1136	(ABC) transporter
DMR_RS20170	COG0577	efflux transmembrane transporter activity
DMR_RS20195	COG3706	GGDEF domain
DMR_RS20230	COG2198	Histidine kinase
DMR_RS20230	COG0643	Histidine kinase
DMR_RS20235	COG0643	Histidine kinase
DMR_RS20235	COG2198	Histidine kinase
DMR_RS20250	COG1940	carbohydrate kinase activity
DMR_RS20280	COG4942	peptidase
DMR_RS20280	COG1388	LysM domain
DMR_RS20305	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DMR_RS20310	COG1640	4-alpha-glucanotransferase
DMR_RS20320	COG0596	Alpha beta hydrolase
DMR_RS20325	COG0179	Fumarylacetoacetate (FAA) hydrolase
DMR_RS20330	COG0616	signal peptide processing
DMR_RS20340	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DMR_RS20345	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DMR_RS20380	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DMR_RS20400	COG0284	orotidine-5'-phosphate decarboxylase activity
DMR_RS20410	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DMR_RS20425	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DMR_RS20440	COG0784	Response regulator, receiver
DMR_RS20440	COG2205	protein histidine kinase activity
DMR_RS20500	COG0493	'glutamate synthase
DMR_RS20500	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DMR_RS20510	COG3383	formate dehydrogenase (NAD+) activity
DMR_RS20515	COG0243	molybdopterin cofactor binding
DMR_RS20525	COG0840	transmembrane signaling receptor activity
DMR_RS20555	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DMR_RS20575	COG1309	transcriptional regulator
DMR_RS20590	COG0737	Belongs to the 5'-nucleotidase family
DMR_RS20595	COG1522	sequence-specific DNA binding
DMR_RS20600	COG1012	belongs to the aldehyde dehydrogenase family
DMR_RS20610	COG3093	addiction module antidote protein HigA
DMR_RS20625	COG0513	Belongs to the DEAD box helicase family
DMR_RS20640	COG1131	(ABC) transporter
DMR_RS20645	COG0842	Transport permease protein
DMR_RS20665	COG2201	protein-glutamate methylesterase activity
DMR_RS20670	COG0784	Response regulator, receiver
DMR_RS20670	COG2205	protein histidine kinase activity
DMR_RS20670	COG2198	Histidine kinase
DMR_RS20705	COG0528	UMP kinase activity
DMR_RS20710	COG0730	response to heat
DMR_RS20715	COG0348	domain, Protein
DMR_RS20720	COG0745	RESPONSE REGULATOR receiver
DMR_RS20730	COG0534	Mate efflux family protein
DMR_RS20740	COG1136	(ABC) transporter
DMR_RS20740	COG0577	efflux transmembrane transporter activity
DMR_RS20765	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DMR_RS20775	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DMR_RS20815	COG0739	heme binding
DMR_RS20825	COG0784	Response regulator, receiver
DMR_RS20825	COG0835	chemotaxis
DMR_RS20830	COG1132	(ABC) transporter
DMR_RS20845	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DMR_RS20855	COG2045	Belongs to the ComB family
DMR_RS20880	COG2860	membrane
DMR_RS20905	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DMR_RS20905	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DMR_RS20915	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DMR_RS20925	COG2192	nodulation
DMR_RS20935	COG0840	transmembrane signaling receptor activity
DMR_RS20935	COG3290	protein histidine kinase activity
DMR_RS20945	COG1522	sequence-specific DNA binding
DMR_RS20990	COG5001	Diguanylate cyclase
DMR_RS20990	COG3300	MHYT domain
DMR_RS20995	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DMR_RS21065	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DMR_RS21070	COG1254	Belongs to the acylphosphatase family
DMR_RS21075	COG2003	Belongs to the UPF0758 family
DMR_RS21090	COG0531	amino acid
DMR_RS21125	COG0330	HflC and HflK could
DMR_RS21145	COG0765	amino acid transport
DMR_RS21150	COG0765	amino acid transport
DMR_RS21155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DMR_RS21175	COG0484	heat shock protein binding
DMR_RS21190	COG1663	tetraacyldisaccharide 4'-kinase activity
DMR_RS21195	COG0670	Belongs to the BI1 family
DMR_RS21205	COG4608	Belongs to the ABC transporter superfamily
DMR_RS21220	COG4957	zinc ion binding
DMR_RS21235	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DMR_RS21240	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DMR_RS21245	COG0138	bifunctional purine biosynthesis protein purh
DMR_RS21265	COG1677	Flagellar hook-basal body complex protein FliE
DMR_RS21275	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DMR_RS21285	COG1157	protein secretion by the type III secretion system
DMR_RS21290	COG0436	Aminotransferase
DMR_RS21295	COG0784	Response regulator, receiver
DMR_RS21295	COG2205	protein histidine kinase activity
DMR_RS21350	COG3678	ATP-independent chaperone mediated protein folding
DMR_RS21375	COG0463	Glycosyl transferase, family 2
DMR_RS21415	COG0640	Transcriptional regulator
DMR_RS21425	COG0784	Response regulator, receiver
DMR_RS21425	COG2205	protein histidine kinase activity
DMR_RS21430	COG4977	sequence-specific DNA binding
DMR_RS21445	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DMR_RS21490	COG0583	DNA-binding transcription factor activity
DMR_RS21505	COG0191	fructose-bisphosphate aldolase activity
DMR_RS21515	COG0697	spore germination
DMR_RS21525	COG0784	Response regulator, receiver
DMR_RS21525	COG2198	Histidine kinase
DMR_RS21525	COG2205	protein histidine kinase activity
DMR_RS21560	COG0756	dUTP diphosphatase activity
DMR_RS21565	COG0686	Belongs to the AlaDH PNT family
DMR_RS21575	COG0058	SHG alpha-glucan phosphorylase activity
DMR_RS21620	COG1639	'signal transduction protein
DMR_RS21660	COG1067	ATP-dependent peptidase activity
DMR_RS21665	COG2814	Major facilitator Superfamily
DMR_RS21685	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DMR_RS21690	COG5002	protein histidine kinase activity
DMR_RS21700	COG1489	DNA binding
DMR_RS21710	COG3852	Histidine kinase
DMR_RS21715	COG2204	response regulator
DMR_RS21725	COG1111	helicase
DMR_RS21725	COG1205	dead DEAH box helicase
DMR_RS21760	COG0493	'glutamate synthase
DMR_RS21795	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DMR_RS21800	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DMR_RS21810	COG1580	Controls the rotational direction of flagella during chemotaxis
DMR_RS21825	COG1338	Plays a role in the flagellum-specific transport system
DMR_RS21830	COG1987	bacterial-type flagellum assembly
DMR_RS21850	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DMR_RS21855	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DMR_RS21890	COG0187	DNA topoisomerase II activity
DMR_RS21905	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DMR_RS21915	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DMR_RS21945	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DMR_RS21945	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DMR_RS21985	COG0129	dihydroxy-acid dehydratase activity
DMR_RS22215	COG0840	transmembrane signaling receptor activity
DMR_RS22240	COG2091	lysine biosynthetic process via aminoadipic acid
DMR_RS22245	COG2205	protein histidine kinase activity
DMR_RS22245	COG0784	Response regulator, receiver
DMR_RS22250	COG0784	Response regulator, receiver
DMR_RS22250	COG2205	protein histidine kinase activity
DMR_RS22255	COG0681	Belongs to the peptidase S26 family
DMR_RS22265	COG2205	protein histidine kinase activity
DMR_RS22265	COG0784	Response regulator, receiver
DMR_RS22280	COG0840	transmembrane signaling receptor activity
DMR_RS22285	COG0840	transmembrane signaling receptor activity
DMR_RS22290	COG0840	transmembrane signaling receptor activity
DMR_RS22295	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DMR_RS22300	COG0745	RESPONSE REGULATOR receiver
DMR_RS22310	COG0840	transmembrane signaling receptor activity
DMR_RS22320	COG2205	protein histidine kinase activity
DMR_RS22320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DMR_RS22325	COG5002	protein histidine kinase activity
DMR_RS22355	COG5002	protein histidine kinase activity
DMR_RS22360	COG0732	type I restriction modification DNA specificity domain
DMR_RS22380	COG0784	Response regulator, receiver
DMR_RS22380	COG2205	protein histidine kinase activity
DMR_RS22390	COG5002	protein histidine kinase activity
DMR_RS22390	COG0784	Response regulator, receiver
DMR_RS22410	COG0784	Response regulator, receiver
DMR_RS22410	COG5002	protein histidine kinase activity
DMR_RS22445	COG0784	Response regulator, receiver
DMR_RS22445	COG2205	protein histidine kinase activity
DMR_RS22460	COG4566	intracellular signal transduction
DMR_RS22470	COG0745	RESPONSE REGULATOR receiver
DMR_RS22480	COG0776	regulation of translation
DMR_RS22485	COG4566	intracellular signal transduction
DMR_RS22520	COG1475	DNA binding
DMR_RS22535	COG2703	oxygen carrier activity
DMR_RS22555	COG5002	protein histidine kinase activity
DMR_RS22565	COG1215	transferase activity, transferring glycosyl groups
DMR_RS22585	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DMR_RS22590	COG0542	response to heat
DMR_RS22595	COG0455	bacterial-type flagellum organization
DMR_RS22645	COG0784	Response regulator, receiver
DMR_RS22645	COG2205	protein histidine kinase activity
DMR_RS22660	COG2205	protein histidine kinase activity
DMR_RS22660	COG0784	Response regulator, receiver
DMR_RS22670	COG0784	Response regulator, receiver
DMR_RS22670	COG2205	protein histidine kinase activity
DMR_RS22675	COG3706	GGDEF domain