locus-tag	class	description
E8L03_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
E8L03_RS00020	ENOG4105BZU	Histidine kinase
E8L03_RS00030	ENOG4105VEQ	Cold shock protein
E8L03_RS00035	ENOG4105VEQ	Cold shock protein
E8L03_RS00050	ENOG4108HM5	NADH-ubiquinone oxidoreductase chain 49kDa
E8L03_RS00060	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
E8L03_RS00065	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
E8L03_RS00070	ENOG4105D65	subunit l
E8L03_RS00085	ENOG4105PGM	cation diffusion facilitator family transporter
E8L03_RS00090	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
E8L03_RS00105	ENOG4105C8U	phosphate abc transporter
E8L03_RS00110	ENOG4105HFZ	Membrane
E8L03_RS00115	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
E8L03_RS00120	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
E8L03_RS00145	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
E8L03_RS00165	ENOG4108IYU	L-aspartate oxidase
E8L03_RS00170	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
E8L03_RS00175	ENOG4105C01	Dihydroxy-acid dehydratase
E8L03_RS00190	ENOG4107REC	cytoplasmic protein
E8L03_RS00195	ENOG4107R1Q	Membrane protein FdrA
E8L03_RS00210	ENOG4105C1A	potassium transporter peripheral membrane
E8L03_RS00260	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
E8L03_RS00285	ENOG4107QHF	type ii secretion system protein e
E8L03_RS00300	ENOG4108V1U	phospholipid-binding protein
E8L03_RS00305	ENOG4107PPM	cobalt chelatase
E8L03_RS00310	ENOG4105BZU	Histidine kinase
E8L03_RS00365	ENOG4105EJQ	L-serine dehydratase
E8L03_RS00395	ENOG4105IDI	abc transporter atp-binding protein
E8L03_RS00460	ENOG4105DJ9	glucan biosynthesis protein
E8L03_RS00475	ENOG4105BZU	Histidine kinase
E8L03_RS00520	ENOG4105CZN	Potassium uptake protein
E8L03_RS00525	ENOG4107ZYR	domain protein
E8L03_RS00530	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
E8L03_RS00550	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E8L03_RS00560	ENOG41082AN	stage II sporulation protein
E8L03_RS00585	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E8L03_RS00590	ENOG4107RBB	ABC transporter, permease
E8L03_RS00610	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
E8L03_RS00615	ENOG4107T8Q	Glycosyl transferase (Group 1
E8L03_RS00625	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
E8L03_RS00630	ENOG4105EQK	-acetyltransferase
E8L03_RS00670	ENOG4105DHJ	ABC, transporter
E8L03_RS00710	ENOG4108JEJ	Pyruvoyl-dependent arginine decarboxylase
E8L03_RS00725	ENOG4105C75	arginyL-tRNA synthetase
E8L03_RS00730	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
E8L03_RS00745	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
E8L03_RS00755	ENOG4107ZAZ	Oligosaccharyl transferase, STT3 subunit
E8L03_RS00755	ENOG4107ZAZ	Oligosaccharyl transferase, STT3 subunit
E8L03_RS00760	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
E8L03_RS00780	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
E8L03_RS00785	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
E8L03_RS00795	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
E8L03_RS00810	ENOG4108URH	decarboxylase
E8L03_RS00815	ENOG4105CY0	Metallo-Beta-Lactamase
E8L03_RS00820	ENOG4106H78	methyltransferase
E8L03_RS00830	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
E8L03_RS00835	ENOG4105JFG	SpoIID LytB domain protein
E8L03_RS00840	ENOG4105MA4	psp1 domain protein
E8L03_RS00845	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
E8L03_RS00855	ENOG4108K88	Membrane
E8L03_RS00870	ENOG4105EZ5	reductase
E8L03_RS00875	ENOG4108JUB	Transcriptional regulator
E8L03_RS00880	ENOG4105C3M	thioredoxin reductase
E8L03_RS00905	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E8L03_RS00910	ENOG4107HP6	Transcriptional regulator
E8L03_RS00915	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
E8L03_RS00925	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8L03_RS00935	ENOG4105CTX	dehydratase
E8L03_RS00940	ENOG4107YRA	Uptake of L-rhamnose across the boundary membrane with the concomitant transport of protons into the cell (symport system) (By similarity)
E8L03_RS01005	ENOG4105DF6	Fe-S oxidoreductase
E8L03_RS01010	ENOG4105DF6	Fe-S oxidoreductase
E8L03_RS01030	ENOG4105CJ1	ABC, transporter
E8L03_RS01040	ENOG4105CH6	catalase
E8L03_RS01075	ENOG4108HRK	Histidine kinase
E8L03_RS01080	ENOG4105DY9	regulatoR
E8L03_RS01100	ENOG4105C8S	subunit m
E8L03_RS01115	ENOG4108JPZ	Monovalent cation H antiporter subunit D
E8L03_RS01120	ENOG4108JPZ	Monovalent cation H antiporter subunit D
E8L03_RS01125	ENOG4105MKQ	Monovalent cation H antiporter subunit C
E8L03_RS01160	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
E8L03_RS01205	ENOG4105K64	Glycosyl transferase, family 2
E8L03_RS01210	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
E8L03_RS01215	ENOG4105K64	Glycosyl transferase, family 2
E8L03_RS01225	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
E8L03_RS01250	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E8L03_RS01260	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
E8L03_RS01275	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
E8L03_RS01280	ENOG4108HHA	Transketolase
E8L03_RS01285	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
E8L03_RS01295	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
E8L03_RS01305	ENOG4105C5E	polysaccharide biosynthesis protein
E8L03_RS01310	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
E8L03_RS01315	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
E8L03_RS01320	ENOG4107SJB	teichoic acid biosynthesis
E8L03_RS01330	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
E8L03_RS01335	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
E8L03_RS01340	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
E8L03_RS01345	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
E8L03_RS01355	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
E8L03_RS01360	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
E8L03_RS01365	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
E8L03_RS01375	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
E8L03_RS01380	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
E8L03_RS01385	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
E8L03_RS01390	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
E8L03_RS01395	ENOG41082SA	50s ribosomal protein l29
E8L03_RS01400	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
E8L03_RS01405	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
E8L03_RS01415	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
E8L03_RS01420	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
E8L03_RS01425	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
E8L03_RS01430	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
E8L03_RS01435	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
E8L03_RS01440	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
E8L03_RS01445	ENOG41087HB	50S ribosomal protein L30
E8L03_RS01450	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
E8L03_RS01455	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
E8L03_RS01470	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
E8L03_RS01480	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
E8L03_RS01490	ENOG4108ZT0	50S ribosomal protein l17
E8L03_RS01505	ENOG4105CI3	gtp-binding protein typa
E8L03_RS01540	ENOG4108IAJ	Nad-dependent epimerase dehydratase
E8L03_RS01555	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
E8L03_RS01560	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
E8L03_RS01565	ENOG4107EFR	Flavocytochrome c
E8L03_RS01580	ENOG4108KK1	membrane protein AbrB duplication
E8L03_RS01595	ENOG4108SHN	Glycosyl transferase, family 2
E8L03_RS01610	ENOG4107QXV	Phosphate transporter
E8L03_RS01615	ENOG4105BZU	Histidine kinase
E8L03_RS01625	ENOG4106VK6	Flagellar motor protein
E8L03_RS01660	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
E8L03_RS01670	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
E8L03_RS01715	ENOG4105D3Q	Sugar transferase
E8L03_RS01720	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8L03_RS01730	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
E8L03_RS01740	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
E8L03_RS01745	ENOG4105C2C	drug resistance transporter, Bcr CflA
E8L03_RS01755	ENOG4105EAB	amino acid AbC transporter
E8L03_RS01760	ENOG4105E5Q	amino acid AbC transporter
E8L03_RS01785	ENOG4105HTX	biosynthesis protein
E8L03_RS01820	ENOG4107BJW	polysaccharide deacetylase
E8L03_RS01840	ENOG4107R51	Glycosyl transferase, family 2
E8L03_RS01870	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS01875	ENOG4105VFE	sira family
E8L03_RS01885	ENOG4105EWK	phytoene
E8L03_RS01915	ENOG4105HF9	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
E8L03_RS01925	ENOG4108DBC	nitroreductase
E8L03_RS01975	ENOG4105CF7	AraC family transcriptional regulator
E8L03_RS01995	ENOG41090A1	ferritin
E8L03_RS02010	ENOG4105DQU	oxidoreductase, subunit beta
E8L03_RS02030	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
E8L03_RS02035	ENOG4105CHH	sulfate transporter
E8L03_RS02045	ENOG4105DQU	oxidoreductase, subunit beta
E8L03_RS02050	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
E8L03_RS02070	ENOG4105C34	Pseudouridine synthase
E8L03_RS02075	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
E8L03_RS02080	ENOG4105C2W	permease
E8L03_RS02090	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
E8L03_RS02100	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
E8L03_RS02135	ENOG4105C8Q	Methyl-accepting chemotaxis
E8L03_RS02155	ENOG4107U14	binding-protein-dependent transport systems inner membrane Component
E8L03_RS02165	ENOG4105VNH	ABC transporter solute-binding protein
E8L03_RS02170	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E8L03_RS02180	ENOG4107XQ1	cobalamin (vitamin B12) biosynthesis CbiM protein
E8L03_RS02185	ENOG4108A51	
E8L03_RS02185	ENOG4108A51	
E8L03_RS02210	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
E8L03_RS02220	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
E8L03_RS02240	ENOG4105C0H	protease
E8L03_RS02245	ENOG4105GR3	Histidine kinase
E8L03_RS02250	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E8L03_RS02260	ENOG4105BZU	Histidine kinase
E8L03_RS02285	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
E8L03_RS02305	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
E8L03_RS02310	ENOG4105BZU	Histidine kinase
E8L03_RS02320	ENOG4105K4P	CoA-binding domain protein
E8L03_RS02330	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
E8L03_RS02340	ENOG4105DKB	L-sorbosone dehydrogenase
E8L03_RS02355	ENOG4105DIW	FeS assembly protein SUFB
E8L03_RS02360	ENOG4105C3K	feS assembly ATPase SufC
E8L03_RS02375	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
E8L03_RS02380	ENOG4105FR1	rard protein
E8L03_RS02385	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
E8L03_RS02395	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
E8L03_RS02410	ENOG4105I03	Flagellin
E8L03_RS02415	ENOG4105EEQ	Na H antiporter
E8L03_RS02420	ENOG4107TT5	NLP P60 protein
E8L03_RS02425	ENOG4105E3B	Multicopper oxidase
E8L03_RS02460	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
E8L03_RS02500	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
E8L03_RS02505	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
E8L03_RS02510	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
E8L03_RS02520	ENOG410873E	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
E8L03_RS02530	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
E8L03_RS02535	ENOG4105CEY	Amp-dependent synthetase and ligase
E8L03_RS02540	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
E8L03_RS02545	ENOG4105DZS	Phenylacetate-CoA ligase
E8L03_RS02550	ENOG410890F	Dynamin family
E8L03_RS02565	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
E8L03_RS02585	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
E8L03_RS02650	ENOG4105C7K	acetolactate synthase
E8L03_RS02660	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
E8L03_RS02695	ENOG4105H1G	trap transporter solute receptor taxi family
E8L03_RS02700	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
E8L03_RS02705	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
E8L03_RS02710	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E8L03_RS02715	ENOG4105BZU	Histidine kinase
E8L03_RS02735	ENOG4107U4H	Methyl-accepting chemotaxis
E8L03_RS02755	ENOG41082YX	Transcriptional regulator, arsr family
E8L03_RS02765	ENOG41084T3	4fe-4S ferredoxin iron-sulfur binding domain-containing protein
E8L03_RS02770	ENOG4108J2R	molybdopterin oxidoreductase
E8L03_RS02780	ENOG4108IJ9	(ABC) transporter
E8L03_RS02790	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
E8L03_RS02820	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS02825	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
E8L03_RS02855	ENOG4105CVN	desaturase
E8L03_RS02880	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS02890	ENOG4105MFQ	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity)
E8L03_RS02895	ENOG4105HRV	phosphonate c-p lyase system protein phnl
E8L03_RS02900	ENOG4105ENV	phosphonate C-P lyase system protein PhnK
E8L03_RS02905	ENOG4105FT8	Phosphonate metabolism
E8L03_RS02925	ENOG4105FDP	GntR family transcriptional regulator
E8L03_RS02930	ENOG4105FD8	phosphonate metabolism protein PhnM
E8L03_RS02940	ENOG4106ZX3	phosphonate ABC transporter, periplasmic phosphonate-binding protein
E8L03_RS02960	ENOG4105MFQ	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity)
E8L03_RS02965	ENOG4105FD8	phosphonate metabolism protein PhnM
E8L03_RS02975	ENOG4105BZU	Histidine kinase
E8L03_RS02980	ENOG4105K64	Glycosyl transferase, family 2
E8L03_RS02990	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
E8L03_RS03010	ENOG4105CKK	Glycosyl transferase, family 2
E8L03_RS03020	ENOG4105CG5	Glycosyl transferase (Group 1
E8L03_RS03045	ENOG4108QV3	biosynthesis protein
E8L03_RS03105	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS03130	ENOG4107V1M	polysaccharide export protein
E8L03_RS03140	ENOG4108RZE	Tetr family transcriptional regulator
E8L03_RS03145	ENOG4105ENX	hydrolase
E8L03_RS03150	ENOG4105CK5	oxidoreductase
E8L03_RS03175	ENOG4105C6N	Formate acetyltransferase
E8L03_RS03185	ENOG4108JUB	Transcriptional regulator
E8L03_RS03195	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E8L03_RS03215	ENOG4105CIH	Imidazole acetol-phosphate transaminase
E8L03_RS03235	ENOG4105BZS	acriflavin resistance protein
E8L03_RS03250	ENOG4105QUH	Domain of unknown function (DUF2088)
E8L03_RS03255	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
E8L03_RS03280	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
E8L03_RS03290	ENOG4108JJA	ABC, transporter
E8L03_RS03315	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
E8L03_RS03340	ENOG41060M0	Crispr-associated protein, cse4 family
E8L03_RS03355	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
E8L03_RS03360	ENOG4105PWE	CRISPR-associated protein cas2
E8L03_RS03400	ENOG4108Z6B	deaminase
E8L03_RS03405	ENOG4108ETH	Formylglycinamide ribotide synthetase
E8L03_RS03415	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
E8L03_RS03420	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E8L03_RS03430	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
E8L03_RS03435	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
E8L03_RS03445	ENOG4105KPI	PTS system sorbose subfamily IIB component
E8L03_RS03455	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
E8L03_RS03460	ENOG4105BZU	Histidine kinase
E8L03_RS03470	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
E8L03_RS03495	ENOG4105BZU	Histidine kinase
E8L03_RS03505	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
E8L03_RS03510	ENOG4108JU5	Magnesium and cobalt efflux protein
E8L03_RS03520	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
E8L03_RS03525	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
E8L03_RS03540	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
E8L03_RS03545	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
E8L03_RS03550	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
E8L03_RS03555	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
E8L03_RS03560	ENOG4105VIE	preprotein translocase, subunit YajC
E8L03_RS03565	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E8L03_RS03570	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E8L03_RS03580	ENOG4105EUB	pirin domain protein
E8L03_RS03595	ENOG4108IYU	L-aspartate oxidase
E8L03_RS03605	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
E8L03_RS03610	ENOG4105CJW	magnesium transporter
E8L03_RS03615	ENOG4105BZU	Histidine kinase
E8L03_RS03625	ENOG4105VDW	Csbd family
E8L03_RS03710	ENOG4108IAJ	Nad-dependent epimerase dehydratase
E8L03_RS03715	ENOG4107JPU	
E8L03_RS03750	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
E8L03_RS03760	ENOG4108IFG	nitrite reductase, (NAD(P)H)
E8L03_RS03770	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
E8L03_RS03775	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
E8L03_RS03780	ENOG4105CNU	cell division protein FtsK
E8L03_RS03805	ENOG4105VFE	sira family
E8L03_RS03810	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
E8L03_RS03830	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E8L03_RS03835	ENOG4105CHM	Aminotransferase
E8L03_RS03840	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E8L03_RS03850	ENOG4108JYZ	YitT family
E8L03_RS03875	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
E8L03_RS03905	ENOG4105CP7	Triose-phosphate isomerase
E8L03_RS03940	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
E8L03_RS03945	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
E8L03_RS03965	ENOG4108JQB	penicillin-binding protein 1C
E8L03_RS03970	ENOG4105DN3	alpha-2-macroglobulin domain protein
E8L03_RS03975	ENOG4105E4C	Lytic transglycosylase catalytic
E8L03_RS03985	ENOG4108Z7R	Chaperone CsaA
E8L03_RS04040	ENOG4105D9P	serine threonine protein kinase
E8L03_RS04075	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
E8L03_RS04105	ENOG4108SHN	Glycosyl transferase, family 2
E8L03_RS04120	ENOG4105HF0	Membrane
E8L03_RS04130	ENOG4107YCY	Transcriptional regulator
E8L03_RS04145	ENOG4105C0H	protease
E8L03_RS04150	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
E8L03_RS04155	ENOG4105CAS	nag kinase
E8L03_RS04175	ENOG4105C94	Transporter
E8L03_RS04180	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
E8L03_RS04230	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
E8L03_RS04250	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
E8L03_RS04255	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
E8L03_RS04270	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
E8L03_RS04275	ENOG4105C1A	potassium transporter peripheral membrane
E8L03_RS04280	ENOG4108317	Binds directly to 16S ribosomal RNA (By similarity)
E8L03_RS04285	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
E8L03_RS04290	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
E8L03_RS04295	ENOG4107Z50	Involved in DNA repair and RecF pathway recombination (By similarity)
E8L03_RS04300	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
E8L03_RS04305	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
E8L03_RS04315	ENOG4108JA2	transcriptioN-repair coupling factor
E8L03_RS04320	ENOG4108V3W	Chemotaxis protein, CheW
E8L03_RS04330	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
E8L03_RS04335	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
E8L03_RS04340	ENOG410829W	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
E8L03_RS04345	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
E8L03_RS04350	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E8L03_RS04355	ENOG4108097	ATP-binding protein
E8L03_RS04360	ENOG4105CFH	Aspartokinase
E8L03_RS04365	ENOG4105BZU	Histidine kinase
E8L03_RS04370	ENOG4105BZU	Histidine kinase
E8L03_RS04385	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E8L03_RS04390	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
E8L03_RS04395	ENOG4105C98	muts2 protein
E8L03_RS04405	ENOG41084JP	30S ribosomal protein S21
E8L03_RS04415	ENOG4105K70	DNA-binding protein
E8L03_RS04420	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
E8L03_RS04425	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
E8L03_RS04440	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
E8L03_RS04450	ENOG4107SG8	outer membrane assembly lipoprotein YfiO
E8L03_RS04455	ENOG4105C3M	thioredoxin reductase
E8L03_RS04460	ENOG4105K63	Thioredoxin
E8L03_RS04495	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
E8L03_RS04500	ENOG4105E4C	Lytic transglycosylase catalytic
E8L03_RS04505	ENOG4105D1F	ATP-binding protein
E8L03_RS04510	ENOG4108UM1	dedA family
E8L03_RS04515	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
E8L03_RS04520	ENOG4105W87	Cbs domain
E8L03_RS04540	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
E8L03_RS04545	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
E8L03_RS04550	ENOG4108EKN	Biotin protein ligase C terminal domain
E8L03_RS04560	ENOG4107XM9	(LipO)protein
E8L03_RS04570	ENOG4105C8N	cysteinyl-tRNA synthetase
E8L03_RS04575	ENOG4105ERG	peptidase m48, ste24p
E8L03_RS04585	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
E8L03_RS04590	ENOG4107Z7S	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
E8L03_RS04600	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
E8L03_RS04605	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
E8L03_RS04610	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
E8L03_RS04620	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
E8L03_RS04635	ENOG4108USZ	hydrogenase
E8L03_RS04650	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
E8L03_RS04655	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
E8L03_RS04660	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
E8L03_RS04675	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
E8L03_RS04690	ENOG4105C3M	thioredoxin reductase
E8L03_RS04700	ENOG4105EGD	dinuclear metal center protein, YbgI family
E8L03_RS04740	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
E8L03_RS04780	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
E8L03_RS04790	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
E8L03_RS04800	ENOG410830I	Protein CrcB homolog
E8L03_RS04805	ENOG4105KJJ	Uncharacterized ACR, COG1993
E8L03_RS04810	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
E8L03_RS04815	ENOG4105BZU	Histidine kinase
E8L03_RS04820	ENOG4105CBS	Chea signal transduction histidine kinase
E8L03_RS04825	ENOG4108VYJ	response regulator receiver protein
E8L03_RS04835	ENOG4105C8Q	Methyl-accepting chemotaxis
E8L03_RS04840	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
E8L03_RS04850	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
E8L03_RS04870	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E8L03_RS04885	ENOG4108YZG	isomerase
E8L03_RS04915	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
E8L03_RS04935	ENOG4105DGU	Histone deacetylase
E8L03_RS04945	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
E8L03_RS05005	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
E8L03_RS05010	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS05030	ENOG4107QQM	Cysteine-rich domain
E8L03_RS05035	ENOG4108SX7	hmc operon protein 5
E8L03_RS05045	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
E8L03_RS05050	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
E8L03_RS05055	ENOG4105F1C	cytochrome c
E8L03_RS05100	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
E8L03_RS05105	ENOG4108FN7	Aldo keto reductase
E8L03_RS05115	ENOG4105BZP	glycoside hydrolase 15-related
E8L03_RS05120	ENOG4105CS1	NAD(P)H quinone oxidoreductase
E8L03_RS05140	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
E8L03_RS05145	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
E8L03_RS05150	ENOG4105C0A	alcohol dehydrogenase
E8L03_RS05155	ENOG4107SJI	Dehydrogenase
E8L03_RS05160	ENOG4105DZC	cytosine deaminase
E8L03_RS05180	ENOG4107FQX	Alpha-acetolactate decarboxylase
E8L03_RS05185	ENOG4105C1J	atp-dependent rna helicase
E8L03_RS05190	ENOG4108IJ9	(ABC) transporter
E8L03_RS05195	ENOG4105BZ7	extracellular solute-binding protein family 1
E8L03_RS05210	ENOG4105CJ1	ABC, transporter
E8L03_RS05225	ENOG4105CKK	Glycosyl transferase, family 2
E8L03_RS05240	ENOG4107STW	synthase
E8L03_RS05315	ENOG4105DJ9	glucan biosynthesis protein
E8L03_RS05320	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
E8L03_RS05325	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
E8L03_RS05330	ENOG4105KHS	type IV fimbrial pilin protein
E8L03_RS05340	ENOG4108JUA	Transcriptional regulator
E8L03_RS05355	ENOG4105E4G	Type IV pilus
E8L03_RS05380	ENOG4108JUA	Transcriptional regulator
E8L03_RS05400	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
E8L03_RS05405	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
E8L03_RS05420	ENOG4105I03	Flagellin
E8L03_RS05425	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E8L03_RS05430	ENOG4105C0D	helicase
E8L03_RS05435	ENOG4105C6X	Major Facilitator
E8L03_RS05450	ENOG4105CEP	NADH dehydrogenase
E8L03_RS05460	ENOG4108UUM	single-stranded DNA-binding protein
E8L03_RS05475	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
E8L03_RS05480	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
E8L03_RS05490	ENOG4106VK6	Flagellar motor protein
E8L03_RS05495	ENOG4105E14	MotA TolQ exbB proton channel
E8L03_RS05500	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
E8L03_RS05555	ENOG4107RBB	ABC transporter, permease
E8L03_RS05560	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
E8L03_RS05575	ENOG4107QPH	glycogen) synthase
E8L03_RS05585	ENOG4105CPQ	Dehydrogenase
E8L03_RS05620	ENOG4108JQ5	ABC transporter
E8L03_RS05625	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
E8L03_RS05630	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
E8L03_RS05635	ENOG4105E43	Extracellular solute-binding protein, family 5
E8L03_RS05645	ENOG4107RSM	transcriptional regulator
E8L03_RS05665	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
E8L03_RS05670	ENOG4105EQI	Metal Dependent Phosphohydrolase
E8L03_RS05675	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
E8L03_RS05700	ENOG4107QI6	Cysteine desulfurase
E8L03_RS05710	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
E8L03_RS05715	ENOG4105DA4	cytochrome c-type biogenesis protein
E8L03_RS05730	ENOG41060IM	Heme exporter protein
E8L03_RS05750	ENOG4105C32	Amino acid ABC transporter (Permease)
E8L03_RS05755	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
E8L03_RS05760	ENOG4105C0Z	ABC transporter
E8L03_RS05765	ENOG4108IV0	ABC, transporter
E8L03_RS05770	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E8L03_RS05785	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
E8L03_RS05790	ENOG4105CTQ	phosphohexokinase
E8L03_RS05795	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
E8L03_RS05835	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E8L03_RS05840	ENOG4105BZU	Histidine kinase
E8L03_RS05855	ENOG4105C79	DNA protecting protein DprA
E8L03_RS05885	ENOG4108V3W	Chemotaxis protein, CheW
E8L03_RS05890	ENOG4107QJE	Chromosome Partitioning Protein
E8L03_RS05895	ENOG4105BZU	Histidine kinase
E8L03_RS05905	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
E8L03_RS05920	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
E8L03_RS05925	ENOG4107U4H	Methyl-accepting chemotaxis
E8L03_RS05935	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
E8L03_RS05940	ENOG4105Q9Y	Universal stress protein
E8L03_RS05950	ENOG4105WH1	Two component transcriptional regulator luxr family
E8L03_RS05960	ENOG4108M4U	conserved membrane protein
E8L03_RS06005	ENOG4105CQZ	Histidine kinase
E8L03_RS06055	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
E8L03_RS06080	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E8L03_RS06085	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
E8L03_RS06090	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
E8L03_RS06095	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
E8L03_RS06100	ENOG4107QN2	dihydrolipoyl dehydrogenase
E8L03_RS06105	ENOG4105UYK	outer membrane protein a
E8L03_RS06115	ENOG4105D3R	alkyl hydroperoxide reductase
E8L03_RS06125	ENOG4105F4G	Membrane
E8L03_RS06130	ENOG4105G6Z	alkaline phosphatase
E8L03_RS06150	ENOG4105D58	Diguanylate phosphodiesterase
E8L03_RS06160	ENOG4105II7	pyrroline-5-carboxylate reductase
E8L03_RS06165	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
E8L03_RS06170	ENOG4105PXI	polysaccharide deacetylase
E8L03_RS06175	ENOG4105CN1	protease
E8L03_RS06190	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
E8L03_RS06195	ENOG4105DRP	amino acid AbC transporter
E8L03_RS06200	ENOG4105EAD	ABC transporter
E8L03_RS06205	ENOG4107RP9	extracellular solute-binding protein, family 3
E8L03_RS06225	ENOG4105C8Y	Acetylornithine aminotransferase
E8L03_RS06240	ENOG4107UZ6	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)
E8L03_RS06270	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
E8L03_RS06275	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
E8L03_RS06280	ENOG4105BZU	Histidine kinase
E8L03_RS06285	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E8L03_RS06295	ENOG4105DPN	Oligoendopeptidase f
E8L03_RS06300	ENOG4105C25	Primosomal protein n'
E8L03_RS06305	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
E8L03_RS06310	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
E8L03_RS06320	ENOG4105C8B	TIGR00159 family
E8L03_RS06325	ENOG4105EEI	dihydropteroate synthase
E8L03_RS06330	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
E8L03_RS06340	ENOG4105CH7	arginosuccinase
E8L03_RS06345	ENOG4105CDH	Citrulline--aspartate ligase
E8L03_RS06350	ENOG4105DBV	ornithine carbamoyltransferase
E8L03_RS06370	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
E8L03_RS06375	ENOG41084FD	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
E8L03_RS06380	ENOG4105CTJ	Metal Dependent Phosphohydrolase
E8L03_RS06385	ENOG4105C9A	Phoh family
E8L03_RS06410	ENOG4105CEV	competence damage-inducible protein
E8L03_RS06415	ENOG4107QY8	reductase
E8L03_RS06420	ENOG4107QWJ	nitrate reductase beta subunit
E8L03_RS06465	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
E8L03_RS06470	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E8L03_RS06495	ENOG4105C8Q	Methyl-accepting chemotaxis
E8L03_RS06500	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E8L03_RS06520	ENOG4105CZX	twitching motility protein
E8L03_RS06525	ENOG4105CZX	twitching motility protein
E8L03_RS06535	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
E8L03_RS06540	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
E8L03_RS06550	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E8L03_RS06565	ENOG4105C26	Dehydrogenase
E8L03_RS06585	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
E8L03_RS06610	ENOG4105VB9	50S ribosomal protein l28
E8L03_RS06620	ENOG41084CW	50S ribosomal protein L32
E8L03_RS06630	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
E8L03_RS06635	ENOG4105CHR	reductase
E8L03_RS06640	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
E8L03_RS06645	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E8L03_RS06655	ENOG4108UK2	deaminase
E8L03_RS06660	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
E8L03_RS06665	ENOG4108R6K	riboflavin synthase, subunit alpha
E8L03_RS06670	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
E8L03_RS06675	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
E8L03_RS06700	ENOG4105W5Q	DNA repair protein (RadC
E8L03_RS06705	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
E8L03_RS06710	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
E8L03_RS06735	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS06755	ENOG4105BZU	Histidine kinase
E8L03_RS06760	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
E8L03_RS06765	ENOG4105CFM	UPF0317 protein
E8L03_RS06775	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
E8L03_RS06800	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
E8L03_RS06805	ENOG4105BZU	Histidine kinase
E8L03_RS06840	ENOG4105D06	uba thif-type nad fad binding protein
E8L03_RS06855	ENOG41083X2	DNA polymerase III, epsilon subunit
E8L03_RS06865	ENOG4107QN1	sodium solute
E8L03_RS06880	ENOG4105DXN	mazG family
E8L03_RS06885	ENOG4105CAT	Cytidine monophosphate kinase
E8L03_RS06890	ENOG4105CIH	Imidazole acetol-phosphate transaminase
E8L03_RS06895	ENOG4105Q9Y	Universal stress protein
E8L03_RS06910	ENOG4105CEV	competence damage-inducible protein
E8L03_RS06935	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
E8L03_RS06940	ENOG4105D48	metallophosphoesterase
E8L03_RS06945	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
E8L03_RS06960	ENOG4105BZU	Histidine kinase
E8L03_RS06965	ENOG4105C7H	Helicase, RecD TraA family
E8L03_RS06970	ENOG4105BZU	Histidine kinase
E8L03_RS06975	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
E8L03_RS06980	ENOG4107ZC0	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
E8L03_RS06990	ENOG4108UQV	Membrane
E8L03_RS07020	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
E8L03_RS07025	ENOG41080HI	glycine oxidase
E8L03_RS07030	ENOG4107KMQ	bfd domain protein (2fe-2s)-binding domain protein
E8L03_RS07040	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
E8L03_RS07045	ENOG4105CBC	glutamate synthase
E8L03_RS07055	ENOG4105EYU	Glutamine amido-transferase
E8L03_RS07060	ENOG4105C5F	glutamine synthetase
E8L03_RS07075	ENOG4107KGK	dmso reductase anchor subunit
E8L03_RS07080	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
E8L03_RS07085	ENOG4107QY8	reductase
E8L03_RS07095	ENOG4108ZXC	Two component transcriptional regulator, luxr family
E8L03_RS07100	ENOG4105BZU	Histidine kinase
E8L03_RS07105	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E8L03_RS07110	ENOG4105BZU	Histidine kinase
E8L03_RS07115	ENOG4108JUA	Transcriptional regulator
E8L03_RS07120	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
E8L03_RS07125	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
E8L03_RS07135	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8L03_RS07140	ENOG4105C26	Dehydrogenase
E8L03_RS07150	ENOG4105VP7	SAF domain protein
E8L03_RS07155	ENOG4105CTX	dehydratase
E8L03_RS07165	ENOG41086B8	CoB-CoM heterodisulfide reductase
E8L03_RS07170	ENOG4107QN2	dihydrolipoyl dehydrogenase
E8L03_RS07190	ENOG4107SHJ	sulfite reductase subunit b
E8L03_RS07220	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
E8L03_RS07225	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
E8L03_RS07240	ENOG4105ENH	Sulfatase
E8L03_RS07265	ENOG4105CF7	AraC family transcriptional regulator
E8L03_RS07270	ENOG4105F9N	Major Facilitator Superfamily
E8L03_RS07280	ENOG4108FN7	Aldo keto reductase
E8L03_RS07285	ENOG4105C8M	UPF0272 protein
E8L03_RS07295	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
E8L03_RS07300	ENOG41067MG	lrgb family
E8L03_RS07310	ENOG4105CMU	LysR family (Transcriptional regulator
E8L03_RS07315	ENOG4105C28	cystathionine
E8L03_RS07320	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8L03_RS07325	ENOG41069H7	transport system small permease component
E8L03_RS07330	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
E8L03_RS07335	ENOG4108MRH	transcriptional regulatory protein
E8L03_RS07340	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
E8L03_RS07345	ENOG4108SGR	YheO domain-containing protein
E8L03_RS07375	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
E8L03_RS07415	ENOG4105CTX	dehydratase
E8L03_RS07420	ENOG4105VP7	SAF domain protein
E8L03_RS07425	ENOG4105QUH	Domain of unknown function (DUF2088)
E8L03_RS07435	ENOG4108JUA	Transcriptional regulator
E8L03_RS07440	ENOG4108PJD	permease
E8L03_RS07450	ENOG4107SDU	Methyl-accepting chemotaxis
E8L03_RS07460	ENOG4107NQ8	LysR family Transcriptional regulator
E8L03_RS07475	ENOG4107YZX	Universal stress protein
E8L03_RS07495	ENOG41080XS	Cobyrinic acid ac-diamide synthase
E8L03_RS07500	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
E8L03_RS07515	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
E8L03_RS07520	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
E8L03_RS07525	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8L03_RS07530	ENOG4105CHM	Aminotransferase
E8L03_RS07535	ENOG4105CQB	FAD linked oxidase domain protein
E8L03_RS07540	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
E8L03_RS07550	ENOG4105DUM	transcriptional regulator, lysR family
E8L03_RS07555	ENOG4105C6K	Malic enzyme
E8L03_RS07560	ENOG4105QUH	Domain of unknown function (DUF2088)
E8L03_RS07570	ENOG4105DIQ	Transcriptional regulator
E8L03_RS07575	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E8L03_RS07605	ENOG4105CC5	ABC transporter
E8L03_RS07610	ENOG4105DIK	(ABC) transporter
E8L03_RS07620	ENOG4107SIG	periplasmic solute binding protein
E8L03_RS07645	ENOG4105C59	p-type ATPase
E8L03_RS07660	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
E8L03_RS07670	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
E8L03_RS07675	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
E8L03_RS07680	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8L03_RS07685	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
E8L03_RS07695	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
E8L03_RS07700	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
E8L03_RS07705	ENOG41084M4	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
E8L03_RS07710	ENOG4108753	50S ribosomal protein l34
E8L03_RS07740	ENOG4108J6I	peptidase, M16
E8L03_RS07750	ENOG4107QX8	SPFH domain, Band 7 family protein
E8L03_RS07765	ENOG4107PPM	cobalt chelatase
E8L03_RS07770	ENOG4105EHG	Permease protein
E8L03_RS07775	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
E8L03_RS07795	ENOG4105C3G	gtp-binding protein
E8L03_RS07800	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
E8L03_RS07805	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
E8L03_RS07815	ENOG4105C0B	DNA polymerase III (alpha subunit)
E8L03_RS07820	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
E8L03_RS07825	ENOG4108KQ5	Integrase catalytic subunit
E8L03_RS07835	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
E8L03_RS07840	ENOG4107QQR	Sporulation
E8L03_RS07860	ENOG4105E14	MotA TolQ exbB proton channel
E8L03_RS07865	ENOG4106VK6	Flagellar motor protein
E8L03_RS07885	ENOG4105W00	Flagellar hook capping protein
E8L03_RS07890	ENOG4105BZE	flagellar hook protein, FlgE
E8L03_RS07895	ENOG4105I03	Flagellin
E8L03_RS07900	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
E8L03_RS07925	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
E8L03_RS07930	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
E8L03_RS07940	ENOG4105D4A	Cell wall formation (By similarity)
E8L03_RS07945	ENOG4105DFU	Cell wall formation (By similarity)
E8L03_RS07955	ENOG4105CNI	cell division protein FtsW
E8L03_RS07965	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
E8L03_RS07970	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
E8L03_RS07975	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
E8L03_RS07980	ENOG4105CJN	penicillin-binding protein
E8L03_RS07990	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
E8L03_RS08000	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E8L03_RS08050	ENOG410829K	Lysine exporter protein (Lyse ygga)
E8L03_RS08055	ENOG4108J2R	molybdopterin oxidoreductase
E8L03_RS08070	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
E8L03_RS08075	ENOG4108UJD	30S ribosomal protein S9
E8L03_RS08080	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
E8L03_RS08100	ENOG4105C8Q	Methyl-accepting chemotaxis
E8L03_RS08105	ENOG4105BZU	Histidine kinase
E8L03_RS08125	ENOG4105ERG	peptidase m48, ste24p
E8L03_RS08130	ENOG4105F8J	Adenylate Guanylate cyclase
E8L03_RS08135	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E8L03_RS08145	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS08180	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
E8L03_RS08200	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E8L03_RS08210	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
E8L03_RS08220	ENOG4105CVE	Lytic murein transglycosylase
E8L03_RS08250	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
E8L03_RS08270	ENOG4105D58	Diguanylate phosphodiesterase
E8L03_RS08275	ENOG4107QHF	type ii secretion system protein e
E8L03_RS08280	ENOG4105EU4	polysulphide reductase NrfD
E8L03_RS08285	ENOG4107SFQ	iron-sulfur binding
E8L03_RS08290	ENOG4107UQT	molybdopterin oxidoreductase
E8L03_RS08300	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
E8L03_RS08320	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
E8L03_RS08330	ENOG4105EPW	hflc protein
E8L03_RS08335	ENOG4107QJR	hflk protein
E8L03_RS08340	ENOG4107QKV	phosphomannomutase
E8L03_RS08345	ENOG4105CHM	Aminotransferase
E8L03_RS08350	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS08355	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
E8L03_RS08370	ENOG4107QI1	Mate efflux family protein
E8L03_RS08385	ENOG4108JQ9	ABC transporter
E8L03_RS08395	ENOG4105UIB	(ABC) transporter
E8L03_RS08405	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
E8L03_RS08420	ENOG41090WU	lipolytic protein G-D-S-L family
E8L03_RS08425	ENOG4105BZU	Histidine kinase
E8L03_RS08430	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
E8L03_RS08440	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
E8L03_RS08445	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
E8L03_RS08450	ENOG4105N42	UPF0307 protein
E8L03_RS08460	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
E8L03_RS08480	ENOG4105C8Q	Methyl-accepting chemotaxis
E8L03_RS08485	ENOG4105BZU	Histidine kinase
E8L03_RS08490	ENOG4105BZU	Histidine kinase
E8L03_RS08495	ENOG4105CA9	Pyruvate kinase
E8L03_RS08535	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
E8L03_RS08565	ENOG4105BZU	Histidine kinase
E8L03_RS08575	ENOG41061AI	Protein of unknown function (DUF2905)
E8L03_RS08585	ENOG4105HF9	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
E8L03_RS08595	ENOG4108UQS	dipeptidase
E8L03_RS08600	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
E8L03_RS08635	ENOG4105K78	MarR family Transcriptional regulator
E8L03_RS08660	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
E8L03_RS08665	ENOG4107WHI	formate dehydrogenase, beta subunit
E8L03_RS08690	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E8L03_RS08765	ENOG4105BZU	Histidine kinase
E8L03_RS08775	ENOG4105BZU	Histidine kinase
E8L03_RS08815	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
E8L03_RS08835	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
E8L03_RS08840	ENOG4105EB3	Histidine kinase
E8L03_RS08865	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
E8L03_RS08880	ENOG4105SYT	Methylenetetrahydrofolate reductase
E8L03_RS08885	ENOG4105M6F	mutator MutT protein
E8L03_RS08920	ENOG4108JJB	ABC transporter
E8L03_RS08935	ENOG4105DC8	reductase
E8L03_RS08965	ENOG4105C8V	SAICAR synthetase
E8L03_RS08970	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
E8L03_RS08980	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
E8L03_RS09005	ENOG4105ESV	Glycosyl transferase, family 4
E8L03_RS09035	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
E8L03_RS09050	ENOG4105F0R	Cytidylyltransferase
E8L03_RS09070	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
E8L03_RS09075	ENOG4105DKW	ABC transporter
E8L03_RS09095	ENOG4108VYJ	response regulator receiver protein
E8L03_RS09120	ENOG4106M28	alanine racemase domain protein
E8L03_RS09130	ENOG4105D0M	Protease HtpX homolog
E8L03_RS09135	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
E8L03_RS09145	ENOG4105BZU	Histidine kinase
E8L03_RS09150	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
E8L03_RS09155	ENOG4105CBS	Chea signal transduction histidine kinase
E8L03_RS09160	ENOG4105C8Q	Methyl-accepting chemotaxis
E8L03_RS09160	ENOG4105C8Q	Methyl-accepting chemotaxis
E8L03_RS09170	ENOG4105BZU	Histidine kinase
E8L03_RS09180	ENOG4108IJ7	Glycine betaine
E8L03_RS09195	ENOG4105BZU	Histidine kinase
E8L03_RS09200	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
E8L03_RS09215	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
E8L03_RS09235	ENOG4105BZU	Histidine kinase
E8L03_RS09245	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
E8L03_RS09295	ENOG4106855	Competence protein
E8L03_RS09310	ENOG4105EMN	RNA polymerase sigma factor
E8L03_RS09315	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E8L03_RS09335	ENOG4105C6T	cysteine synthase
E8L03_RS09365	ENOG41083MR	nifu domain-containing protein
E8L03_RS09370	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
E8L03_RS09375	ENOG4105D58	Diguanylate phosphodiesterase
E8L03_RS09380	ENOG4105CJR	Integral membrane protein (MviN
E8L03_RS09385	ENOG4107VT3	K03386 peroxiredoxin (alkyl hydroperoxide reductase subunit C) EC 1.11.1.15
E8L03_RS09400	ENOG4105C7K	acetolactate synthase
E8L03_RS09410	ENOG4107U4H	Methyl-accepting chemotaxis
E8L03_RS09420	ENOG4105BZU	Histidine kinase
E8L03_RS09425	ENOG4105CIY	formyltetrahydrofolate deformylase
E8L03_RS09430	ENOG4105D64	Mechanosensitive ion channel
E8L03_RS09440	ENOG4105HMI	Membrane
E8L03_RS09445	ENOG4105DUM	transcriptional regulator, lysR family
E8L03_RS09455	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
E8L03_RS09460	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
E8L03_RS09465	ENOG4105CHM	Aminotransferase
E8L03_RS09470	ENOG4105D6E	homoserine dehydrogenase
E8L03_RS09475	ENOG4105E3H	phosphoglycerate mutase
E8L03_RS09480	ENOG4107YD3	Thioesterase
E8L03_RS09490	ENOG4107RZH	Nitrite and sulphite reductase 4Fe-4S region
E8L03_RS09535	ENOG4105CHR	reductase
E8L03_RS09555	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
E8L03_RS09565	ENOG4105CN5	Metallo-Beta-Lactamase
E8L03_RS09570	ENOG4105CE9	30S ribosomal protein S2
E8L03_RS09580	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
E8L03_RS09600	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
E8L03_RS09605	ENOG4105DZP	Membrane-associated zinc metalloprotease
E8L03_RS09610	ENOG41072GX	Peptidase M22 Glycoprotease
E8L03_RS09615	ENOG4105I03	Flagellin
E8L03_RS09625	ENOG4105MQ3	flagellar protein FliS
E8L03_RS09640	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
E8L03_RS09660	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
E8L03_RS09665	ENOG4105D52	delta-aminolevulinic acid dehydratase
E8L03_RS09685	ENOG4108SX7	hmc operon protein 5
E8L03_RS09710	ENOG4107RIQ	Sulfate adenylate transferase
E8L03_RS09725	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E8L03_RS09730	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
E8L03_RS09750	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
E8L03_RS09755	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
E8L03_RS09765	ENOG4105CQB	FAD linked oxidase domain protein
E8L03_RS09770	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
E8L03_RS09775	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
E8L03_RS09780	ENOG4105KZ7	phosphocarrier protein hpr
E8L03_RS09790	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
E8L03_RS09795	ENOG41082RQ	UPF0102 protein
E8L03_RS09800	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
E8L03_RS09805	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
E8L03_RS09810	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
E8L03_RS09820	ENOG4105VB6	UPF0109 protein
E8L03_RS09825	ENOG4105K5M	30s ribosomal protein S16
E8L03_RS09840	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E8L03_RS09845	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E8L03_RS09855	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
E8L03_RS09870	ENOG4105C32	Amino acid ABC transporter (Permease)
E8L03_RS09880	ENOG4105C0Z	ABC transporter
E8L03_RS09885	ENOG4108IV0	ABC, transporter
E8L03_RS09890	ENOG4105DZS	Phenylacetate-CoA ligase
E8L03_RS09910	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
E8L03_RS09915	ENOG4105C30	Nad-dependent epimerase dehydratase
E8L03_RS09935	ENOG4108WBK	V-type ATP synthase subunit D
E8L03_RS09940	ENOG4107RQX	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
E8L03_RS09945	ENOG4107RVI	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
E8L03_RS09960	ENOG4105BZU	Histidine kinase
E8L03_RS09985	ENOG410630Q	Methylamine utilization
E8L03_RS10000	ENOG4105VFU	Rna-binding protein
E8L03_RS10005	ENOG4105CJR	Integral membrane protein (MviN
E8L03_RS10010	ENOG4105BZ8	glutamate synthase
E8L03_RS10065	ENOG4105CX6	glutaminyL-tRNA synthetase
E8L03_RS10070	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
E8L03_RS10080	ENOG4105BZU	Histidine kinase
E8L03_RS10110	ENOG4108IV0	ABC, transporter
E8L03_RS10115	ENOG4105C0Z	ABC transporter
E8L03_RS10125	ENOG4105C32	Amino acid ABC transporter (Permease)
E8L03_RS10150	ENOG4108JCI	Transcriptional regulator
E8L03_RS10170	ENOG4105C8Q	Methyl-accepting chemotaxis
E8L03_RS10180	ENOG4105DIH	basic membrane
E8L03_RS10185	ENOG4105CVK	Glutamate decarboxylase
E8L03_RS10225	ENOG4108HMX	isocitrate dehydrogenase (NADP)
E8L03_RS10240	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E8L03_RS10250	ENOG4105BZU	Histidine kinase
E8L03_RS10255	ENOG4105FS7	Transcriptional regulator
E8L03_RS10270	ENOG4105BZ1	(ABC) transporter
E8L03_RS10290	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
E8L03_RS10295	ENOG4105C4M	(Ubiquinol oxidase) subunit I
E8L03_RS10300	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
E8L03_RS10310	ENOG4105VCQ	rubredoxin
E8L03_RS10315	ENOG4107U4H	Methyl-accepting chemotaxis
E8L03_RS10320	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
E8L03_RS10325	ENOG4105EAH	synthase
E8L03_RS10345	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
E8L03_RS10360	ENOG4105E4R	Precorrin-3B C17-methyltransferase
E8L03_RS10365	ENOG4108P62	biosynthesis protein (CbiG)
E8L03_RS10370	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
E8L03_RS10380	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
E8L03_RS10385	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
E8L03_RS10390	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
E8L03_RS10395	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
E8L03_RS10400	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
E8L03_RS10410	ENOG41081F0	Precorrin-8x methylmutase
E8L03_RS10415	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
E8L03_RS10430	ENOG4106MP8	UPF0754 membrane protein
E8L03_RS10465	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
E8L03_RS10470	ENOG4107S2Z	UPF0761 membrane protein
E8L03_RS10475	ENOG4108IQE	Amp-dependent synthetase and ligase
E8L03_RS10520	ENOG4108V3W	Chemotaxis protein, CheW
E8L03_RS10525	ENOG4105C8Q	Methyl-accepting chemotaxis
E8L03_RS10560	ENOG410841Q	phosphoesterase PA-phosphatase related protein
E8L03_RS10570	ENOG4107S9Q	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
E8L03_RS10580	ENOG4107R91	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
E8L03_RS10615	ENOG4105BZU	Histidine kinase
E8L03_RS10625	ENOG4108Z0Z	intracellular protease Pfpi family
E8L03_RS10685	ENOG41082IR	Excinuclease ABC C subunit domain protein
E8L03_RS10705	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
E8L03_RS10710	ENOG4105VFU	Rna-binding protein
E8L03_RS10715	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
E8L03_RS10730	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
E8L03_RS10740	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
E8L03_RS10755	ENOG4105BZU	Histidine kinase
E8L03_RS10780	ENOG4105C8Q	Methyl-accepting chemotaxis
E8L03_RS10790	ENOG4105D0M	Protease HtpX homolog
E8L03_RS10810	ENOG4105CW7	secretion protein, HlyD family
E8L03_RS10815	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
E8L03_RS10825	ENOG4105EQ0	Major Facilitator superfamily
E8L03_RS10840	ENOG4108JUB	Transcriptional regulator
E8L03_RS10850	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
E8L03_RS10855	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
E8L03_RS10895	ENOG4105EM7	Selenocysteine-specific translation elongation factor
E8L03_RS10900	ENOG4105DFM	M18 family aminopeptidase
E8L03_RS10910	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
E8L03_RS10915	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
E8L03_RS10950	ENOG4107R3N	Filamentation induced by cAMP protein fic
E8L03_RS10955	ENOG4107QMH	DNA methylase
E8L03_RS10975	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
E8L03_RS10980	ENOG41069D7	Methyl-accepting chemotaxis
E8L03_RS11000	ENOG4105DMF	Dehydrogenase
E8L03_RS11010	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS11015	ENOG4105DAA	L-lactate
E8L03_RS11020	ENOG4105CQB	FAD linked oxidase domain protein
E8L03_RS11025	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
E8L03_RS11030	ENOG4105C6K	Malic enzyme
E8L03_RS11035	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
E8L03_RS11045	ENOG4107QR9	Iron-sulfur cluster binding protein
E8L03_RS11055	ENOG4107VRP	DNA repair exonuclease
E8L03_RS11070	ENOG4105F0R	Cytidylyltransferase
E8L03_RS11125	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
E8L03_RS11175	ENOG4105CIF	Ornithine Cyclodeaminase
E8L03_RS11190	ENOG4105CBX	hi0933 family
E8L03_RS11210	ENOG4105C5I	Dehydrogenase
E8L03_RS11215	ENOG4105HEE	Binding Domain protein
E8L03_RS11235	ENOG4105ECR	NmrA family
E8L03_RS11240	ENOG4105CHR	reductase
E8L03_RS11275	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
E8L03_RS11280	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
E8L03_RS11320	ENOG4108R96	Methyltransferase, YaeB family
E8L03_RS11325	ENOG4105VKD	bioY protein
E8L03_RS11330	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
E8L03_RS11335	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
E8L03_RS11345	ENOG4105C4R	Atp-dependent dna helicase
E8L03_RS11365	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
E8L03_RS11375	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E8L03_RS11400	ENOG4105KVH	Transcriptional regulator
E8L03_RS11405	ENOG4105CS1	NAD(P)H quinone oxidoreductase
E8L03_RS11410	ENOG4106TD9	Diguanylate cyclase
E8L03_RS11430	ENOG4105D9P	serine threonine protein kinase
E8L03_RS11500	ENOG4106P37	HTH-type transcriptional regulator YjhI
E8L03_RS11515	ENOG4105DQU	oxidoreductase, subunit beta
E8L03_RS11535	ENOG4105CK7	Sodium proline symporter
E8L03_RS11540	ENOG4105KPY	Small multidrug resistance protein
E8L03_RS11545	ENOG4105CQB	FAD linked oxidase domain protein
E8L03_RS11550	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
E8L03_RS11560	ENOG4108JUA	Transcriptional regulator
E8L03_RS11565	ENOG41089BK	Glutamine amido-transferase
E8L03_RS11575	ENOG4105F4R	Transcriptional regulator mode
E8L03_RS11605	ENOG4105CBS	Chea signal transduction histidine kinase
E8L03_RS11615	ENOG4108V3W	Chemotaxis protein, CheW
E8L03_RS11625	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
E8L03_RS11630	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
E8L03_RS11635	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
E8L03_RS11640	ENOG4108IEH	NADH dehydrogenase subunit g
E8L03_RS11650	ENOG4105GKE	subunit e
E8L03_RS11655	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E8L03_RS11660	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
E8L03_RS11665	ENOG4105C4M	(Ubiquinol oxidase) subunit I
E8L03_RS11675	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E8L03_RS11680	ENOG4107UFS	subunit j
E8L03_RS11685	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E8L03_RS11690	ENOG4105D65	subunit l
E8L03_RS11695	ENOG4105C8S	subunit m
E8L03_RS11700	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E8L03_RS11725	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E8L03_RS11730	ENOG4105CHR	reductase
E8L03_RS11735	ENOG4105DEI	Mannitol dehydrogenase
E8L03_RS11740	ENOG4105CMG	Carbohydrate kinase
E8L03_RS11755	ENOG4105EHG	Permease protein
E8L03_RS11770	ENOG4108JJB	ABC transporter
E8L03_RS11775	ENOG4107S16	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
E8L03_RS11815	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
E8L03_RS11830	ENOG4105DSF	transport protein
E8L03_RS11835	ENOG4105DZW	Dipeptidase
E8L03_RS11840	ENOG4107STF	Involved in phosphonate degradation (By similarity)
E8L03_RS11850	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
E8L03_RS11855	ENOG4108JQ7	(ABC) transporter
E8L03_RS11860	ENOG4105C3U	ABC transporter
E8L03_RS11880	ENOG4105DUM	transcriptional regulator, lysR family
E8L03_RS11890	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E8L03_RS11895	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
E8L03_RS11900	ENOG4105E0C	molybdate abc transporter
E8L03_RS11905	ENOG4105F4R	Transcriptional regulator mode
E8L03_RS11910	ENOG4108R96	Methyltransferase, YaeB family
E8L03_RS11955	ENOG41089UC	methyltransferase, type 11
E8L03_RS11965	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E8L03_RS11975	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
E8L03_RS11995	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
E8L03_RS12005	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS12010	ENOG4108S24	Fumarate reduCtase
E8L03_RS12015	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
E8L03_RS12020	ENOG4105E33	succinate dehydrogenase
E8L03_RS12035	ENOG4105C6K	Malic enzyme
E8L03_RS12040	ENOG4107QWE	)-transporter
E8L03_RS12050	ENOG4105BZU	Histidine kinase
E8L03_RS12055	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS12060	ENOG4105C0A	alcohol dehydrogenase
E8L03_RS12070	ENOG41086B8	CoB-CoM heterodisulfide reductase
E8L03_RS12075	ENOG4107QN2	dihydrolipoyl dehydrogenase
E8L03_RS12095	ENOG4107SHJ	sulfite reductase subunit b
E8L03_RS12120	ENOG4108IYU	L-aspartate oxidase
E8L03_RS12130	ENOG4105CIZ	coA-substrate-specific enzyme activase
E8L03_RS12135	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
E8L03_RS12145	ENOG4105BZU	Histidine kinase
E8L03_RS12150	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS12160	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS12165	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS12185	ENOG4105BZU	Histidine kinase
E8L03_RS12195	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E8L03_RS12210	ENOG4105D8X	mechanosensitive ion channel
E8L03_RS12215	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
E8L03_RS12225	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS12240	ENOG4105M3Z	response regulator
E8L03_RS12250	ENOG41067B5	Histone deacetylase superfamily protein
E8L03_RS12265	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
E8L03_RS12275	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS12280	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
E8L03_RS12310	ENOG4105CGK	Exodeoxyribonuclease III
E8L03_RS12325	ENOG4108S24	Fumarate reduCtase
E8L03_RS12330	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
E8L03_RS12335	ENOG4105E33	succinate dehydrogenase
E8L03_RS12350	ENOG4105JAB	phenazine biosynthesis protein, phzf family
E8L03_RS12360	ENOG4107R88	Chemotaxis protein (CheV)
E8L03_RS12365	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
E8L03_RS12375	ENOG4108JQ7	(ABC) transporter
E8L03_RS12385	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E8L03_RS12390	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
E8L03_RS12395	ENOG4105DEF	Extracellular solute-binding protein, family 5
E8L03_RS12410	ENOG4105DWV	Homoserine O-trans-acetylase
E8L03_RS12415	ENOG4108I5G	Major Facilitator superfamily
E8L03_RS12435	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
E8L03_RS12445	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
E8L03_RS12470	ENOG4105Z5G	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
E8L03_RS12475	ENOG4105C0H	protease
E8L03_RS12505	ENOG4105CE1	Ferrous iron transport protein b
E8L03_RS12515	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
E8L03_RS12520	ENOG4105D00	flagellar biosynthetic protein flhB
E8L03_RS12525	ENOG4105D7B	Flagellar biosynthesis protein flha
E8L03_RS12530	ENOG4105FZW	flagellar biosynthesis regulator FlhF
E8L03_RS12540	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E8L03_RS12585	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
E8L03_RS12605	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS12635	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS12645	ENOG4105CBS	Chea signal transduction histidine kinase
E8L03_RS12655	ENOG4108V3W	Chemotaxis protein, CheW
E8L03_RS12670	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS12685	ENOG4107R7Y	intracellular protease Pfpi family
E8L03_RS12695	ENOG4105C4X	radical SAM domain protein
E8L03_RS12700	ENOG4105CBG	Sulfatase
E8L03_RS12730	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E8L03_RS12735	ENOG4107FQ9	ethanolamine ammonia-lyase
E8L03_RS12740	ENOG4105CPD	ethanolamine ammonia-lyase
E8L03_RS12745	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8L03_RS12760	ENOG4108JUB	Transcriptional regulator
E8L03_RS12765	ENOG4108JPW	Aminotransferase
E8L03_RS12775	ENOG4105C32	Amino acid ABC transporter (Permease)
E8L03_RS12785	ENOG4105C0Z	ABC transporter
E8L03_RS12790	ENOG4108IV0	ABC, transporter
E8L03_RS12795	ENOG4105C26	Dehydrogenase
E8L03_RS12800	ENOG4105N14	lysine exporter protein LysE YggA
E8L03_RS12805	ENOG4105BZU	Histidine kinase
E8L03_RS12815	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
E8L03_RS12830	ENOG4108IJ6	ABC transporter
E8L03_RS12840	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
E8L03_RS12845	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS12850	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
E8L03_RS12880	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E8L03_RS12885	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E8L03_RS12895	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
E8L03_RS12900	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8L03_RS12910	ENOG4108MGF	sugar kinase
E8L03_RS12915	ENOG4105D2N	Aldolase
E8L03_RS12920	ENOG4105E98	transcriptional regulator DeoR family
E8L03_RS12930	ENOG4105C0P	Mg chelatase subunit ChlI
E8L03_RS12935	ENOG4105C3F	Signal peptidase i
E8L03_RS12940	ENOG4105C3F	Signal peptidase i
E8L03_RS12945	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
E8L03_RS12960	ENOG4105DY0	carbon monoxide dehydrogenase operon C protein
E8L03_RS12980	ENOG410823F	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
E8L03_RS13000	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
E8L03_RS13010	ENOG4108IYU	L-aspartate oxidase
E8L03_RS13040	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
E8L03_RS13050	ENOG4107QKV	phosphomannomutase
E8L03_RS13060	ENOG4108TGR	phosphatase
E8L03_RS13100	ENOG4105CKK	Glycosyl transferase, family 2
E8L03_RS13110	ENOG4107EF8	Glycosyl transferase (Group 1
E8L03_RS13145	ENOG4107Y2G	Glycosyl transferase (Group 1
E8L03_RS13165	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E8L03_RS13195	ENOG4105C3M	thioredoxin reductase
E8L03_RS13200	ENOG4105K63	Thioredoxin
E8L03_RS13205	ENOG4108MR7	Arylsulfotransferase
E8L03_RS13210	ENOG4105CHR	reductase
E8L03_RS13215	ENOG4105C6K	Malic enzyme
E8L03_RS13220	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E8L03_RS13225	ENOG4108IV0	ABC, transporter
E8L03_RS13230	ENOG4105C0Z	ABC transporter
E8L03_RS13240	ENOG4105C32	Amino acid ABC transporter (Permease)
E8L03_RS13250	ENOG4108R85	Short chain dehydrogenase
E8L03_RS13255	ENOG4105QUH	Domain of unknown function (DUF2088)
E8L03_RS13265	ENOG4105BZA	Phosphoglycerate kinase
E8L03_RS13275	ENOG4107KJX	Transcriptional regulator
E8L03_RS13290	ENOG4108EKI	Dehydrogenase
E8L03_RS13295	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
E8L03_RS13300	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
E8L03_RS13320	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
E8L03_RS13325	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
E8L03_RS13340	ENOG4107U32	Beta-lactamase domain protein
E8L03_RS13345	ENOG4105BZP	glycoside hydrolase 15-related
E8L03_RS13365	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
E8L03_RS13385	ENOG4105C57	major facilitator superfamily
E8L03_RS13400	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
E8L03_RS13410	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
E8L03_RS13415	ENOG4108YZA	Nitrogen regulatory protein pii
E8L03_RS13420	ENOG4105BZU	Histidine kinase
E8L03_RS13425	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
E8L03_RS13435	ENOG4108YZA	Nitrogen regulatory protein pii
E8L03_RS13445	ENOG41061GT	Aldolase
E8L03_RS13450	ENOG41061GT	Aldolase
E8L03_RS13455	ENOG4106M32	3-dehydroquinate synthase
E8L03_RS13460	ENOG4105CQC	Prephenate dehydratase
E8L03_RS13465	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
E8L03_RS13475	ENOG4105CRQ	synthase (Component I)
E8L03_RS13480	ENOG4105DDQ	anthranilate synthase
E8L03_RS13485	ENOG4108I0Q	anthranilate phosphoribosyltransferase
E8L03_RS13490	ENOG4105DK0	Indole-3-glycerol phosphate synthase
E8L03_RS13495	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
E8L03_RS13500	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
E8L03_RS13505	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
E8L03_RS13520	ENOG4105CPI	Metal Dependent Phosphohydrolase
E8L03_RS13545	ENOG4105C0Z	ABC transporter
E8L03_RS13550	ENOG4105CP9	extracellular ligand-binding receptor
E8L03_RS13555	ENOG4105C32	Amino acid ABC transporter (Permease)
E8L03_RS13560	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
E8L03_RS13565	ENOG4108IV0	ABC, transporter
E8L03_RS13595	ENOG41083UI	stage II sporulation protein
E8L03_RS13605	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
E8L03_RS13610	ENOG4105C8W	ABC transporter
E8L03_RS13625	ENOG410812K	response regulator receiver protein
E8L03_RS13650	ENOG4105DZ1	carboxypeptidase
E8L03_RS13660	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
E8L03_RS13670	ENOG4105DC1	bifunctional purine biosynthesis protein purh
E8L03_RS13680	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
E8L03_RS13690	ENOG4107QRG	dna polymerase iii
E8L03_RS13695	ENOG4108VYJ	response regulator receiver protein
E8L03_RS13705	ENOG4105KME	endoribonuclease L-psp
E8L03_RS13710	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E8L03_RS13715	ENOG4105C3M	thioredoxin reductase
E8L03_RS13725	ENOG4105BZU	Histidine kinase
E8L03_RS13730	ENOG410901E	Membrane
E8L03_RS13735	ENOG4105BZA	Phosphoglycerate kinase
E8L03_RS13755	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
E8L03_RS13760	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
E8L03_RS13770	ENOG4105VJV	50s ribosomal protein L35
E8L03_RS13780	ENOG4105C22	threonyL-tRNA synthetase
E8L03_RS13815	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
E8L03_RS13835	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
E8L03_RS13840	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
E8L03_RS13850	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
E8L03_RS13855	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
E8L03_RS13860	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E8L03_RS13880	ENOG4105CNI	cell division protein FtsW
E8L03_RS13885	ENOG4105CJN	penicillin-binding protein
E8L03_RS13905	ENOG4105N5T	Radical SAM Protein
E8L03_RS13920	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
E8L03_RS13930	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
E8L03_RS13935	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
E8L03_RS13955	ENOG4105C34	Pseudouridine synthase
E8L03_RS13960	ENOG4105C6K	Malic enzyme
E8L03_RS13990	ENOG41081FY	multiple antibiotic resistance (MarC)-related
E8L03_RS14015	ENOG4108UQY	Iron-storage protein
E8L03_RS14025	ENOG4108KJ1	Trap dicarboxylate transporter, dctp subunit
E8L03_RS14030	ENOG4108K1J	Transporter DctQ
E8L03_RS14035	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8L03_RS14045	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
E8L03_RS14065	ENOG4105ENR	peptidase, M24
E8L03_RS14070	ENOG4108RYR	transcriptional regulator AsnC family
E8L03_RS14075	ENOG4105DCF	alanine dehydrogenase
E8L03_RS14080	ENOG4105C26	Dehydrogenase
E8L03_RS14085	ENOG4105C8Y	Acetylornithine aminotransferase
E8L03_RS14100	ENOG4107U4H	Methyl-accepting chemotaxis
E8L03_RS14135	ENOG4105KBH	arsR family transcriptional regulator
E8L03_RS14155	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
E8L03_RS14165	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
E8L03_RS14170	ENOG4105DVY	radical SAM domain protein
E8L03_RS14175	ENOG4107Z3H	Transcriptional regulator, TetR family
E8L03_RS14180	ENOG4105E63	Pfam:DUF178
E8L03_RS14185	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
E8L03_RS14210	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
E8L03_RS14215	ENOG4108I5C	dEAD DEAH box helicase
E8L03_RS14220	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS14225	ENOG4105BZU	Histidine kinase
E8L03_RS14235	ENOG4105PW4	Sugar fermentation stimulation protein homolog
E8L03_RS14250	ENOG4105DFA	alanine racemase domain protein
E8L03_RS14255	ENOG4105E14	MotA TolQ exbB proton channel
E8L03_RS14260	ENOG4105ER2	Ompa motb domain protein
E8L03_RS14275	ENOG4105DD5	Flagellar motor switch protein
E8L03_RS14285	ENOG4105CN7	Flagellar biosynthetic protein FliP
E8L03_RS14290	ENOG4105VS8	Flagellar biosynthetic protein fliq
E8L03_RS14305	ENOG4105E2X	shikimate dehydrogenase
E8L03_RS14310	ENOG4105EJ5	oxidoreductase gamma subunit
E8L03_RS14320	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
E8L03_RS14330	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
E8L03_RS14340	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
E8L03_RS14355	ENOG4107QX8	SPFH domain, Band 7 family protein
E8L03_RS14370	ENOG4107QJE	Chromosome Partitioning Protein
E8L03_RS14380	ENOG4105FA0	parb-like partition protein
E8L03_RS14385	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
E8L03_RS14390	ENOG4107SGM	protein serine threonine phosphatase
E8L03_RS14395	ENOG41082AN	stage II sporulation protein
E8L03_RS14400	ENOG4105CY3	ABC transporter, permease
E8L03_RS14425	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
E8L03_RS14440	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
E8L03_RS14445	ENOG4105C9M	aspartyl-trna synthetase
E8L03_RS14450	ENOG4105CUT	histidyl-tRNA synthetase
E8L03_RS14455	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
E8L03_RS14460	ENOG4105C01	Dihydroxy-acid dehydratase
E8L03_RS14465	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
E8L03_RS14470	ENOG4105CAK	Cell division ATP-binding protein ftsE
E8L03_RS14480	ENOG4105C6X	Major Facilitator
E8L03_RS14485	ENOG4105E51	psp operon transcriptional activator
E8L03_RS14490	ENOG41087YS	Phage shock protein A
E8L03_RS14520	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
E8L03_RS14530	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E8L03_RS14535	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E8L03_RS14545	ENOG4105BZU	Histidine kinase
E8L03_RS14565	ENOG4105CEN	a g-specific adenine glycosylase
E8L03_RS14575	ENOG4105WZW	rhodanese family
E8L03_RS14595	ENOG4107YZB	Cobalt transport protein
E8L03_RS14620	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
E8L03_RS14630	ENOG4108MJI	response regulator
E8L03_RS14665	ENOG4108V3W	Chemotaxis protein, CheW
E8L03_RS14670	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
E8L03_RS14675	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
E8L03_RS14680	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
E8L03_RS14690	ENOG4105CD3	dihydroorotase
E8L03_RS14695	ENOG4105CXT	aspartate transcarbamylase
E8L03_RS14700	ENOG410857E	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
E8L03_RS14705	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
E8L03_RS14720	ENOG4105K59	histidine triad (HIT) protein
E8L03_RS14730	ENOG4105K6T	rare lipoprotein A
E8L03_RS14735	ENOG4107SDT	Homocitrate synthase
E8L03_RS14745	ENOG4105DAN	ATP-dependent protease
E8L03_RS14770	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
E8L03_RS14790	ENOG4105BZU	Histidine kinase
E8L03_RS14795	ENOG41081QV	Universal stress protein
E8L03_RS14815	ENOG4105D7N	magnesium and cobalt transport protein CorA
E8L03_RS14820	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS14825	ENOG4105BZU	Histidine kinase
E8L03_RS14830	ENOG4106C08	Zinc resistance-associated protein
E8L03_RS14840	ENOG4105D0M	Protease HtpX homolog
E8L03_RS14850	ENOG4108JUA	Transcriptional regulator
E8L03_RS14855	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
E8L03_RS14860	ENOG4108YZA	Nitrogen regulatory protein pii
E8L03_RS14865	ENOG4108YZA	Nitrogen regulatory protein pii
E8L03_RS14900	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
E8L03_RS14920	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
E8L03_RS14930	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
E8L03_RS14940	ENOG4105CKK	Glycosyl transferase, family 2
E8L03_RS14965	ENOG4105E0Y	RtcB Protein
E8L03_RS14980	ENOG4105MA0	exported protein
E8L03_RS14990	ENOG4108JQC	penicillin-binding protein 1A
E8L03_RS15005	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
E8L03_RS15010	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E8L03_RS15015	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
E8L03_RS15020	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E8L03_RS15025	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
E8L03_RS15040	ENOG4107EJQ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E8L03_RS15045	ENOG4108JPZ	Monovalent cation H antiporter subunit D
E8L03_RS15060	ENOG4105C8S	subunit m
E8L03_RS15065	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E8L03_RS15080	ENOG4105CY1	sulfite reductase, dissimilatory-type alpha subunit
E8L03_RS15085	ENOG4105PJW	Sulfite reductase dissimilatory-type beta subunit
E8L03_RS15090	ENOG4105Z0W	Dissimilatory sulfite reductase D
E8L03_RS15095	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
E8L03_RS15125	ENOG41083J0	(ABC) transporter
E8L03_RS15135	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
E8L03_RS15140	ENOG4105C12	Phosphoribosylglycinamide synthetase
E8L03_RS15145	ENOG4105DZS	Phenylacetate-CoA ligase
E8L03_RS15150	ENOG4105D58	Diguanylate phosphodiesterase
E8L03_RS15155	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
E8L03_RS15170	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
E8L03_RS15175	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
E8L03_RS15180	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
E8L03_RS15190	ENOG4105BZU	Histidine kinase
E8L03_RS15195	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
E8L03_RS15200	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
E8L03_RS15205	ENOG4105D07	Signal peptide peptidase, SppA
E8L03_RS15220	ENOG41082X2	rubredoxin
E8L03_RS15230	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
E8L03_RS15240	ENOG4105C83	adenylosuccinate lyase
E8L03_RS15245	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
E8L03_RS15280	ENOG4105C32	Amino acid ABC transporter (Permease)
E8L03_RS15290	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
E8L03_RS15295	ENOG41061GT	Aldolase
E8L03_RS15310	ENOG4105DTN	riboflavin biosynthesis protein ribF
E8L03_RS15330	ENOG4108S4H	thioesterase Superfamily protein
E8L03_RS15335	ENOG4108VCT	Sulfite exporter TauE/SafE
E8L03_RS15345	ENOG4105BZU	Histidine kinase
E8L03_RS15400	ENOG4107Y2X	deaminase
E8L03_RS15415	ENOG4105UZW	Tail fiber assembly protein
E8L03_RS15550	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
E8L03_RS15555	ENOG4105KT5	UmuD protein
E8L03_RS15615	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
E8L03_RS15620	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS15650	ENOG4105BZU	Histidine kinase
E8L03_RS15655	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E8L03_RS15660	ENOG4105CD5	CoA-binding domain protein
E8L03_RS15665	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E8L03_RS15670	ENOG4108JQC	penicillin-binding protein 1A
E8L03_RS15690	ENOG41074CX	linocin_m18 bacteriocin protein
E8L03_RS15700	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
E8L03_RS15705	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
E8L03_RS15725	ENOG4105FB9	CRISPR-associated protein
E8L03_RS15740	ENOG4105DBI	uridine monophosphokinase
E8L03_RS15765	ENOG4108SHN	Glycosyl transferase, family 2
E8L03_RS15805	ENOG4105DFH	Transport of potassium into the cell (By similarity)
E8L03_RS15810	ENOG4105BZU	Histidine kinase
E8L03_RS15815	ENOG4107258	Transcriptional regulator
E8L03_RS15820	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E8L03_RS15825	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
E8L03_RS15830	ENOG4108K1J	Transporter DctQ
E8L03_RS15835	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8L03_RS15840	ENOG4105C5I	Dehydrogenase
E8L03_RS15845	ENOG4105CNV	Aldolase
E8L03_RS15850	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
E8L03_RS15855	ENOG4105C8Q	Methyl-accepting chemotaxis
E8L03_RS15860	ENOG4105CEV	competence damage-inducible protein
E8L03_RS15875	ENOG4107WHI	formate dehydrogenase, beta subunit
E8L03_RS15885	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
E8L03_RS15930	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS15940	ENOG4105BZU	Histidine kinase
E8L03_RS15970	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
E8L03_RS15975	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS15985	ENOG4105HRV	phosphonate c-p lyase system protein phnl
E8L03_RS15990	ENOG4105ENV	phosphonate C-P lyase system protein PhnK
E8L03_RS15995	ENOG4105FT8	Phosphonate metabolism
E8L03_RS16015	ENOG4107RJJ	Transcriptional regulator
E8L03_RS16020	ENOG4105S7S	phosphonate abc transporter
E8L03_RS16025	ENOG4105D5T	phosphonate abc transporter
E8L03_RS16040	ENOG4107R3N	Filamentation induced by cAMP protein fic
E8L03_RS16050	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
E8L03_RS16055	ENOG410834F	Transcriptional regulator
E8L03_RS16090	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
E8L03_RS16100	ENOG4108VYJ	response regulator receiver protein
E8L03_RS16110	ENOG4105BZU	Histidine kinase
E8L03_RS16120	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E8L03_RS16125	ENOG4105C5X	domain protein
E8L03_RS16130	ENOG4105CUC	YeeE YedE family protein
E8L03_RS16145	ENOG4105E0X	reductase
E8L03_RS16170	ENOG4107QP3	malate synthase g
E8L03_RS16175	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
E8L03_RS16180	ENOG41090EK	ompa motb domain protein
E8L03_RS16190	ENOG4105CUY	Mechanosensitive ion channel
E8L03_RS16200	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
E8L03_RS16205	ENOG4105DG4	malate L-lactate dehydrogenase
E8L03_RS16210	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
E8L03_RS16240	ENOG4107U4H	Methyl-accepting chemotaxis
E8L03_RS16245	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
E8L03_RS16255	ENOG4105VN1	Heat shock protein
E8L03_RS16260	ENOG4105C8Q	Methyl-accepting chemotaxis
E8L03_RS16265	ENOG4105C26	Dehydrogenase
E8L03_RS16270	ENOG4108YXU	transcriptional regulator AsnC family
E8L03_RS16275	ENOG4105BZU	Histidine kinase
E8L03_RS16280	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
E8L03_RS16285	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E8L03_RS16290	ENOG4105D3Q	Sugar transferase
E8L03_RS16300	ENOG4105CGN	Glycosyl transferase (Group 1
E8L03_RS16310	ENOG4105DR5	peptidase
E8L03_RS16315	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
E8L03_RS16320	ENOG4105CIG	ABC transporter
E8L03_RS16350	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E8L03_RS16400	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
E8L03_RS16405	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
E8L03_RS16410	ENOG4105D8X	mechanosensitive ion channel
E8L03_RS16435	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
E8L03_RS16445	ENOG4105BZU	Histidine kinase
E8L03_RS16455	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
E8L03_RS16460	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
E8L03_RS16495	ENOG4108VYJ	response regulator receiver protein
E8L03_RS16525	ENOG4105CIZ	coA-substrate-specific enzyme activase
E8L03_RS16535	ENOG4105CJR	Integral membrane protein (MviN
E8L03_RS16545	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
E8L03_RS16555	ENOG4105C31	Tryptophanyl-tRNA synthetase
E8L03_RS16560	ENOG4108Z4T	Peptidase M50
E8L03_RS16580	ENOG4107R56	PP-loop domain protein
E8L03_RS16585	ENOG4108RYC	glycosyltransferase
E8L03_RS16595	ENOG4108RAV	Conserved protein
E8L03_RS16600	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
E8L03_RS16610	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
E8L03_RS16620	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
E8L03_RS16635	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS16640	ENOG4105BZU	Histidine kinase
E8L03_RS16645	ENOG4105BZU	Histidine kinase
E8L03_RS16660	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
E8L03_RS16670	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E8L03_RS16675	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
E8L03_RS16685	ENOG4105CRK	lysyL-tRNA synthetase
E8L03_RS16695	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
E8L03_RS16705	ENOG4107U4H	Methyl-accepting chemotaxis
E8L03_RS16710	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
E8L03_RS16720	ENOG4108V1U	phospholipid-binding protein
E8L03_RS16725	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E8L03_RS16740	ENOG4105CEY	Amp-dependent synthetase and ligase
E8L03_RS16750	ENOG4108ZXC	Two component transcriptional regulator, luxr family
E8L03_RS16820	ENOG4105DQE	DNA ligase
E8L03_RS16870	ENOG4108W2Y	isochorismatase
E8L03_RS16875	ENOG4105C5S	asparaginyl-tRNA synthetase
E8L03_RS16885	ENOG4105CPC	Aldo Keto reductase
E8L03_RS16920	ENOG4108ZC9	flagellar basal-body rod protein flgc
E8L03_RS16925	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
E8L03_RS16930	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
E8L03_RS16935	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
E8L03_RS16965	ENOG4105D7A	ATP-binding protein
E8L03_RS16980	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
E8L03_RS16985	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
E8L03_RS16995	ENOG4105CBJ	Metal-dependent enzyme
E8L03_RS17000	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
E8L03_RS17005	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
E8L03_RS17030	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
E8L03_RS17045	ENOG4105PM1	preprotein translocase subunit SecE
E8L03_RS17050	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
E8L03_RS17055	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
E8L03_RS17060	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
E8L03_RS17065	ENOG4108VZM	50s ribosomal protein L10
E8L03_RS17070	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
E8L03_RS17075	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E8L03_RS17080	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E8L03_RS17090	ENOG4108ESY	Metal dependent phosphohydrolase
E8L03_RS17095	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
E8L03_RS17105	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
E8L03_RS17125	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
E8L03_RS17135	ENOG4105CM2	brancheD-chain amino acid aminotransferase
E8L03_RS17140	ENOG4105C6E	dna polymerase iii
E8L03_RS17145	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
E8L03_RS17150	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
E8L03_RS17160	ENOG4105F8V	Hydrolase, tatD family
E8L03_RS17165	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
E8L03_RS17180	ENOG4105CSA	Coproporphyrinogen iii oxidase
E8L03_RS17185	ENOG4105WPN	DNA integration recombination invertion protein
E8L03_RS17190	ENOG4107QQB	Ribonuclease E
E8L03_RS17205	ENOG4105DZS	Phenylacetate-CoA ligase
E8L03_RS17215	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
E8L03_RS17220	ENOG4105C88	aminopeptidase
E8L03_RS17225	ENOG4106VK6	Flagellar motor protein
E8L03_RS17230	ENOG4105ER2	Ompa motb domain protein
E8L03_RS17235	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
E8L03_RS17270	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
E8L03_RS17280	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
E8L03_RS17285	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
E8L03_RS17290	ENOG4105CDU	Replicative dna helicase
E8L03_RS17295	ENOG4105DZS	Phenylacetate-CoA ligase
E8L03_RS17310	ENOG4105W87	Cbs domain
E8L03_RS17320	ENOG4105C8M	UPF0272 protein
E8L03_RS17325	ENOG4105CFP	Peptidase U32
E8L03_RS17330	ENOG4105DB7	PHP domain protein
E8L03_RS17335	ENOG4105W49	UPF0434 protein
E8L03_RS17340	ENOG4105C7Z	Conserved Protein
E8L03_RS17345	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
E8L03_RS17360	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
E8L03_RS17365	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
E8L03_RS17370	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
E8L03_RS17375	ENOG4105NBF	ammecr1 domain protein
E8L03_RS17390	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS17390	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS17395	ENOG4105K63	Thioredoxin
E8L03_RS17405	ENOG4108BGM	Quinol dehydrogenase periplasmic component
E8L03_RS17415	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
E8L03_RS17420	ENOG4107R88	Chemotaxis protein (CheV)
E8L03_RS17425	ENOG4105K70	DNA-binding protein
E8L03_RS17440	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
E8L03_RS17445	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E8L03_RS17460	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
E8L03_RS17470	ENOG4105C5H	ABC transporter
E8L03_RS17485	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
E8L03_RS17500	ENOG4105BZE	flagellar hook protein, FlgE
E8L03_RS17505	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS17515	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
E8L03_RS17520	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
E8L03_RS17530	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
E8L03_RS17550	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
E8L03_RS17565	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
E8L03_RS17570	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
E8L03_RS17575	ENOG4105SFS	phosphoesterase RecJ domain protein
E8L03_RS17580	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
E8L03_RS17590	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
E8L03_RS17600	ENOG4105CHV	Transcription elongation factor NusA
E8L03_RS17615	ENOG4105CGA	flagellar basal-body rod protein FlgG
E8L03_RS17620	ENOG4105CGA	flagellar basal-body rod protein FlgG
E8L03_RS17630	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
E8L03_RS17635	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
E8L03_RS17640	ENOG4105DR5	peptidase
E8L03_RS17650	ENOG4105E1Q	flagellar hook-associated protein
E8L03_RS17660	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
E8L03_RS17685	ENOG4108Z03	MAF-like protein
E8L03_RS17705	ENOG4105K5X	acetyltransferase
E8L03_RS17710	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
E8L03_RS17735	ENOG4107Z3H	Transcriptional regulator, TetR family
E8L03_RS17750	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
E8L03_RS17755	ENOG4105VUF	Transcriptional regulator
E8L03_RS17790	ENOG4108Z86	Glutamine amidotransferase
E8L03_RS17800	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
E8L03_RS17815	ENOG4105E4C	Lytic transglycosylase catalytic
E8L03_RS17835	ENOG4108ZF3	Phosphatase
E8L03_RS17840	ENOG4108ZF3	Phosphatase
E8L03_RS17845	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
E8L03_RS17850	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E8L03_RS17855	ENOG4105KCK	Peptidoglycan-associated lipoprotein
E8L03_RS17860	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
E8L03_RS17870	ENOG4105M8F	Biopolymer transport protein exbD tolR
E8L03_RS17875	ENOG4105E02	MotA TolQ exbB proton channel
E8L03_RS17880	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
E8L03_RS17895	ENOG4105BZU	Histidine kinase
E8L03_RS17930	ENOG4107T4Z	adenosine kinase
E8L03_RS17935	ENOG4105VF7	tolerance protein
E8L03_RS17975	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
E8L03_RS17980	ENOG4105K46	50S ribosomal protein l27
E8L03_RS17985	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
E8L03_RS17990	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
E8L03_RS18000	ENOG4105DWF	phosphomethylpyrimidine kinase
E8L03_RS18030	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
E8L03_RS18065	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
E8L03_RS18085	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
E8L03_RS18105	ENOG4105CAQ	asparagine synthetase
E8L03_RS18120	ENOG4107QJE	Chromosome Partitioning Protein
E8L03_RS18130	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
E8L03_RS18135	ENOG4105CPI	Metal Dependent Phosphohydrolase
E8L03_RS18140	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
E8L03_RS18150	ENOG4105BZE	flagellar hook protein, FlgE
E8L03_RS18160	ENOG4105UIB	(ABC) transporter
E8L03_RS18165	ENOG4105C2J	ABC transporter
E8L03_RS18195	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
E8L03_RS18225	ENOG4105CHC	glucokinase (EC 2.7.1.2)
E8L03_RS18235	ENOG4105E66	phosphoriboisomerase A
E8L03_RS18240	ENOG4105BZU	Histidine kinase
E8L03_RS18245	ENOG4105D58	Diguanylate phosphodiesterase
E8L03_RS18260	ENOG4108SX7	hmc operon protein 5
E8L03_RS18265	ENOG4107QQM	Cysteine-rich domain
E8L03_RS18280	ENOG4105EIE	fructose-bisphosphate aldolase
E8L03_RS18290	ENOG4105DDY	UPF0142 protein ycaO
E8L03_RS18300	ENOG4108I0Y	(ABC) transporter
E8L03_RS18305	ENOG4108UJV	acyl-CoA thioesterase i
E8L03_RS18325	ENOG4105BZU	Histidine kinase
E8L03_RS18330	ENOG4108URH	decarboxylase
E8L03_RS18345	ENOG4105DC7	peptidase M24
E8L03_RS18365	ENOG4107QHF	type ii secretion system protein e
E8L03_RS18380	ENOG4105CPK	Glycosyl transferase (Group 1
E8L03_RS18385	ENOG4105C8Q	Methyl-accepting chemotaxis
E8L03_RS18390	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
E8L03_RS18395	ENOG4105C0H	protease
E8L03_RS18405	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
E8L03_RS18425	ENOG4105BZU	Histidine kinase
E8L03_RS18430	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
E8L03_RS18435	ENOG4105CPI	Metal Dependent Phosphohydrolase
E8L03_RS18465	ENOG4105BZU	Histidine kinase
E8L03_RS18470	ENOG4105BZU	Histidine kinase
E8L03_RS18495	ENOG4105DQE	DNA ligase
E8L03_RS18500	ENOG4105DQE	DNA ligase
E8L03_RS18510	ENOG410690C	hydroxylamine oxidase
E8L03_RS18520	ENOG4105UHE	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
E8L03_RS18550	ENOG4108Q71	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
E8L03_RS18575	ENOG4105DJZ	UPF0182 protein
E8L03_RS18590	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
E8L03_RS18595	ENOG4108PCN	EamA-like transporter family
E8L03_RS18600	ENOG4108K01	transcriptional regulator
E8L03_RS18610	ENOG4105BZU	Histidine kinase
E8L03_RS18615	ENOG4105G5W	regulator Fur family
E8L03_RS18625	ENOG4105VCQ	rubredoxin
E8L03_RS18640	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
E8L03_RS18645	ENOG4105G5W	regulator Fur family
E8L03_RS18650	ENOG4108UQY	Iron-storage protein
E8L03_RS18655	ENOG4107TPS	domain protein
E8L03_RS18675	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
E8L03_RS18690	ENOG4105C8Q	Methyl-accepting chemotaxis
E8L03_RS18700	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
E8L03_RS18720	ENOG4105C94	Transporter
E8L03_RS18725	ENOG4108QBF	Transcriptional regulator
E8L03_RS18760	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E8L03_RS18765	ENOG4105D60	lipoprotein releasing system transmembrane protein
E8L03_RS18785	ENOG4107U4H	Methyl-accepting chemotaxis
E8L03_RS18820	ENOG4108IJ9	(ABC) transporter
E8L03_RS18825	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E8L03_RS18830	ENOG4105E98	transcriptional regulator DeoR family
E8L03_RS18835	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
E8L03_RS18840	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
E8L03_RS18855	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
E8L03_RS18860	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
E8L03_RS18880	ENOG4105E0F	Histidine kinase
E8L03_RS18885	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
E8L03_RS18895	ENOG4105I03	Flagellin
E8L03_RS18910	ENOG4105E1Q	flagellar hook-associated protein
E8L03_RS18915	ENOG4105BZE	flagellar hook protein, FlgE
E8L03_RS18920	ENOG4105W00	Flagellar hook capping protein
E8L03_RS18930	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
E8L03_RS18935	ENOG41069H7	transport system small permease component
E8L03_RS18940	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E8L03_RS18960	ENOG4108Q5Y	Membrane
E8L03_RS18970	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
E8L03_RS18975	ENOG4107QW8	radical SAM domain protein
E8L03_RS18980	ENOG4108IJ0	Aspartate ammonia-lyase
E8L03_RS19005	ENOG4107QHI	-hydrogenase
E8L03_RS19015	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
E8L03_RS19020	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
E8L03_RS19025	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E8L03_RS19035	ENOG4105EFJ	Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity)
E8L03_RS19050	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
E8L03_RS19095	ENOG4105C7J	ABC transporter, permease
E8L03_RS19120	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
E8L03_RS19125	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
E8L03_RS19130	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
E8L03_RS19145	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
E8L03_RS19150	ENOG4105KC4	UPF0296 protein
E8L03_RS19160	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
E8L03_RS19165	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
E8L03_RS19170	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
E8L03_RS19175	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
E8L03_RS19185	ENOG4105CFG	Acts as a chaperone (By similarity)
E8L03_RS19190	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
E8L03_RS19195	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
E8L03_RS19225	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
E8L03_RS19325	ENOG4105BZU	Histidine kinase
E8L03_RS19330	ENOG4105HHA	aminodeoxychorismate lyase
E8L03_RS19350	ENOG4108UMN	azlc family
E8L03_RS19355	ENOG4105CQB	FAD linked oxidase domain protein
E8L03_RS19365	ENOG4105CIH	Imidazole acetol-phosphate transaminase
E8L03_RS19370	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
E8L03_RS19390	ENOG4108JQC	penicillin-binding protein 1A
E8L03_RS19420	ENOG4108IAB	Phoh family
E8L03_RS19425	ENOG4105D64	Mechanosensitive ion channel
E8L03_RS19430	ENOG4105BZ8	glutamate synthase
E8L03_RS19435	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
E8L03_RS19445	ENOG4105D2N	Aldolase
E8L03_RS19470	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
E8L03_RS19475	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
E8L03_RS19515	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
E8L03_RS19520	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
E8L03_RS19525	ENOG4105CFP	Peptidase U32
E8L03_RS19540	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
E8L03_RS19545	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
E8L03_RS19560	ENOG410822N	TonB family
E8L03_RS19565	ENOG4105SG9	biopolymer transport protein, ExbD
E8L03_RS19570	ENOG4105E02	MotA TolQ exbB proton channel
E8L03_RS19575	ENOG4105E2Y	ABC, transporter
E8L03_RS19595	ENOG4107ZSV	Receptor
E8L03_RS19610	ENOG4105C3U	ABC transporter
E8L03_RS19615	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E8L03_RS19620	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
E8L03_RS19625	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
E8L03_RS19655	ENOG4105CE1	Ferrous iron transport protein b
E8L03_RS19680	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
E8L03_RS19685	ENOG4105BZU	Histidine kinase
E8L03_RS19730	ENOG4105GIJ	Glycine betaine
E8L03_RS19735	ENOG4108HQS	Glycine betaine
E8L03_RS19740	ENOG4108IJ7	Glycine betaine
E8L03_RS19745	ENOG410690C	hydroxylamine oxidase
E8L03_RS19750	ENOG4105CUW	cytochrome C-TYPE protein
E8L03_RS19775	ENOG4107QWP	ABC-2 type transporter
E8L03_RS19780	ENOG4107QWP	ABC-2 type transporter
E8L03_RS19785	ENOG4105CJ1	ABC, transporter
E8L03_RS19795	ENOG4107MVR	Transcriptional regulator
E8L03_RS19810	ENOG4108RAC	Rubrerythrin
E8L03_RS19845	ENOG4105BZU	Histidine kinase
E8L03_RS19850	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
E8L03_RS19855	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E8L03_RS19875	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
E8L03_RS19885	ENOG4105BZU	Histidine kinase
E8L03_RS19895	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
E8L03_RS19900	ENOG4105VEQ	Cold shock protein
E8L03_RS19905	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
E8L03_RS19945	ENOG4105BZU	Histidine kinase
E8L03_RS19950	ENOG4108R96	Methyltransferase, YaeB family
E8L03_RS19975	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
E8L03_RS19985	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E8L03_RS20010	ENOG4108VPT	UPF0234 protein
E8L03_RS20020	ENOG4108V0P	LemA family
E8L03_RS20030	ENOG4108V0P	LemA family
E8L03_RS20045	ENOG4105D9N	nucleoside
E8L03_RS20055	ENOG4105D17	glycoside hydrolase, family 3 domain protein
E8L03_RS20075	ENOG4105D60	lipoprotein releasing system transmembrane protein
E8L03_RS20120	ENOG4105BZU	Histidine kinase
E8L03_RS20155	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
E8L03_RS20160	ENOG4107NQ8	LysR family Transcriptional regulator
E8L03_RS20190	ENOG4105E5Q	amino acid AbC transporter
E8L03_RS20205	ENOG4105E5Q	amino acid AbC transporter
E8L03_RS20210	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
E8L03_RS20240	ENOG4105BZU	Histidine kinase
E8L03_RS20245	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E8L03_RS20280	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
E8L03_RS20310	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
E8L03_RS20315	ENOG4105CG5	Glycosyl transferase (Group 1
E8L03_RS20320	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E8L03_RS20345	ENOG4105D2T	synthase
E8L03_RS20350	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
E8L03_RS20355	ENOG4108JJB	ABC transporter
E8L03_RS20365	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
E8L03_RS20370	ENOG4105CMR	udp-glucose 4-epimerase
E8L03_RS20385	ENOG4105DIK	(ABC) transporter
E8L03_RS20405	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
E8L03_RS20410	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
E8L03_RS20415	ENOG4107U9B	transcriptional regulator
E8L03_RS20440	ENOG4107QP8	phosphohexose isomerase
E8L03_RS20445	ENOG4107TCE	N-acetyltransferase
E8L03_RS20450	ENOG4108UY2	Chloramphenicol acetyltransferase
E8L03_RS20460	ENOG4105DZ1	carboxypeptidase
E8L03_RS20465	ENOG4105D5T	phosphonate abc transporter
E8L03_RS20490	ENOG4107SFQ	iron-sulfur binding
E8L03_RS20530	ENOG4105DWY	Agmatine deiminase
E8L03_RS20545	ENOG4105D07	Signal peptide peptidase, SppA
E8L03_RS20560	ENOG4107QMS	site-determining protein
E8L03_RS20565	ENOG4105D1F	ATP-binding protein
E8L03_RS20580	ENOG4108JUA	Transcriptional regulator
E8L03_RS20585	ENOG4107RSS	Hydrogenase accessory protein HypB
E8L03_RS20590	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
E8L03_RS20600	ENOG4105C0Z	ABC transporter
E8L03_RS20605	ENOG4105CEY	Amp-dependent synthetase and ligase
E8L03_RS20620	ENOG4105C32	Amino acid ABC transporter (Permease)
E8L03_RS20635	ENOG4108IV0	ABC, transporter
E8L03_RS20670	ENOG4108YZA	Nitrogen regulatory protein pii
E8L03_RS20685	ENOG4106PMH	Extracellular solute-binding protein family 3
E8L03_RS20690	ENOG4105E5Q	amino acid AbC transporter
E8L03_RS20700	ENOG4105FDP	GntR family transcriptional regulator
E8L03_RS20710	ENOG4105CXK	mandelate racemase muconate lactonizing
E8L03_RS20720	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
E8L03_RS20725	ENOG4105CTX	dehydratase
E8L03_RS20730	ENOG4105CTX	dehydratase
E8L03_RS20745	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E8L03_RS20750	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
E8L03_RS20760	ENOG4105CP2	von willebrand factor, type a
E8L03_RS20765	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
E8L03_RS20770	ENOG41065SU	Two-component system sensor kinase
E8L03_RS20780	ENOG4108J5G	6-phosphogluconate dehydrogenase
E8L03_RS20785	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
E8L03_RS20790	ENOG4108HHA	Transketolase
E8L03_RS20795	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
E8L03_RS20820	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
E8L03_RS20825	ENOG4105CDY	transcriptional regulatory protein
E8L03_RS20830	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
E8L03_RS20835	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
E8L03_RS20845	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)