locus-tag	class	description
FGL65_RS00035	COG1538	Outer membrane efflux protein
FGL65_RS00040	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FGL65_RS00050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGL65_RS00070	COG4657	Part of a membrane complex involved in electron transport
FGL65_RS00075	COG4660	Part of a membrane complex involved in electron transport
FGL65_RS00085	COG4658	electron transport chain
FGL65_RS00100	COG0583	DNA-binding transcription factor activity
FGL65_RS00110	COG1346	cytolysis
FGL65_RS00120	COG1124	(ABC) transporter
FGL65_RS00125	COG0444	Belongs to the ABC transporter superfamily
FGL65_RS00130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGL65_RS00135	COG0601	transmembrane transport
FGL65_RS00140	COG0747	negative chemotaxis
FGL65_RS00150	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FGL65_RS00150	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FGL65_RS00170	COG4771	TonB-dependent receptor
FGL65_RS00180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FGL65_RS00185	COG2823	Periplasmic or secreted lipoprotein
FGL65_RS00190	COG0791	NLP P60 protein
FGL65_RS00235	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FGL65_RS00240	COG0459	protein refolding
FGL65_RS00250	COG3706	GGDEF domain
FGL65_RS00280	COG0784	Response regulator, receiver
FGL65_RS00280	COG0835	chemotaxis
FGL65_RS00285	COG2089	acid synthase
FGL65_RS00295	COG0318	PFAM AMP-dependent synthetase and ligase
FGL65_RS00310	COG1797	cobyrinic acid a,c-diamide synthase activity
FGL65_RS00320	COG2221	Nitrite and sulphite reductase 4Fe-4S
FGL65_RS00325	COG2221	Nitrite and sulphite reductase 4Fe-4S
FGL65_RS00355	COG0438	transferase activity, transferring glycosyl groups
FGL65_RS00360	COG0367	asparagine synthase
FGL65_RS00365	COG2264	protein methyltransferase activity
FGL65_RS00375	COG0110	maltose O-acetyltransferase activity
FGL65_RS00385	COG1132	(ABC) transporter
FGL65_RS00400	COG2226	methyltransferase
FGL65_RS00420	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FGL65_RS00430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGL65_RS00435	COG0367	asparagine synthase
FGL65_RS00450	COG0535	radical SAM domain protein
FGL65_RS00460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FGL65_RS00465	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FGL65_RS00470	COG0363	glucosamine-6-phosphate deaminase activity
FGL65_RS00480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGL65_RS00490	COG1846	Transcriptional regulator
FGL65_RS00490	COG1940	carbohydrate kinase activity
FGL65_RS00495	COG0529	Catalyzes the synthesis of activated sulfate
FGL65_RS00500	COG1132	(ABC) transporter
FGL65_RS00505	COG0297	glycogen (starch) synthase activity
FGL65_RS00525	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FGL65_RS00535	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FGL65_RS00535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGL65_RS00540	COG2089	acid synthase
FGL65_RS00550	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FGL65_RS00555	COG1028	Short-chain dehydrogenase reductase Sdr
FGL65_RS00580	COG0107	imidazoleglycerol-phosphate synthase activity
FGL65_RS00585	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FGL65_RS00590	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FGL65_RS00595	COG1083	cytidylyl-transferase
FGL65_RS00600	COG1086	Polysaccharide biosynthesis protein
FGL65_RS00610	COG2089	acid synthase
FGL65_RS00615	COG0463	Glycosyl transferase, family 2
FGL65_RS00615	COG1216	Glycosyl transferase, family 2
FGL65_RS00640	COG5002	protein histidine kinase activity
FGL65_RS00645	COG0668	transmembrane transport
FGL65_RS00660	COG1131	(ABC) transporter
FGL65_RS00675	COG0612	Peptidase, M16
FGL65_RS00680	COG4166	transmembrane transport
FGL65_RS00685	COG4174	ABC transporter (Permease)
FGL65_RS00690	COG4239	(ABC) transporter, permease
FGL65_RS00695	COG4172	Belongs to the ABC transporter superfamily
FGL65_RS00705	COG0811	peptide transport
FGL65_RS00710	COG0811	peptide transport
FGL65_RS00715	COG0848	biopolymer transport protein
FGL65_RS00740	COG1811	Na channel or pump
FGL65_RS00760	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FGL65_RS00775	COG1725	Transcriptional regulator
FGL65_RS00780	COG0861	Integral membrane protein TerC family
FGL65_RS00790	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FGL65_RS00795	COG0363	glucosamine-6-phosphate deaminase activity
FGL65_RS00810	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FGL65_RS00815	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FGL65_RS00820	COG1349	DNA-binding transcription factor activity
FGL65_RS00835	COG0697	spore germination
FGL65_RS00840	COG2207	Transcriptional regulator
FGL65_RS00855	COG0745	RESPONSE REGULATOR receiver
FGL65_RS00860	COG0084	hydrolase, TatD family'
FGL65_RS00865	COG0215	cysteine-tRNA ligase activity
FGL65_RS00875	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FGL65_RS00875	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FGL65_RS00890	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FGL65_RS00910	COG1215	transferase activity, transferring glycosyl groups
FGL65_RS00915	COG0438	transferase activity, transferring glycosyl groups
FGL65_RS00920	COG2204	response regulator
FGL65_RS00925	COG0584	glycerophosphoryl diester phosphodiesterase
FGL65_RS00935	COG3063	Type IV pilus biogenesis stability protein PilW
FGL65_RS00945	COG0616	signal peptide processing
FGL65_RS00950	COG2183	response to ionizing radiation
FGL65_RS00950	COG0539	negative regulation of cytoplasmic translation
FGL65_RS00955	COG0704	Plays a role in the regulation of phosphate uptake
FGL65_RS00960	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FGL65_RS00980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGL65_RS00985	COG0251	oxidation-reduction process
FGL65_RS01010	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FGL65_RS01020	COG1683	Conserved Protein
FGL65_RS01035	COG0697	spore germination
FGL65_RS01055	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FGL65_RS01065	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FGL65_RS01085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGL65_RS01090	COG0765	amino acid transport
FGL65_RS01095	COG1126	abc transporter atp-binding protein
FGL65_RS01110	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FGL65_RS01120	COG4106	trans-aconitate 2-methyltransferase activity
FGL65_RS01140	COG0242	peptide deformylase activity
FGL65_RS01145	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FGL65_RS01150	COG0124	histidyl-tRNA synthetase
FGL65_RS01165	COG0129	dihydroxy-acid dehydratase activity
FGL65_RS01180	COG2608	mercury ion transmembrane transporter activity
FGL65_RS01185	COG2217	Heavy metal translocating P-type atpase
FGL65_RS01195	COG0543	2 iron, 2 sulfur cluster binding
FGL65_RS01200	COG0493	'glutamate synthase
FGL65_RS01215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FGL65_RS01215	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FGL65_RS01230	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FGL65_RS01235	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FGL65_RS01240	COG1360	Flagellar Motor Protein
FGL65_RS01265	COG1338	Plays a role in the flagellum-specific transport system
FGL65_RS01270	COG1987	bacterial-type flagellum assembly
FGL65_RS01295	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FGL65_RS01300	COG1388	LysM domain
FGL65_RS01300	COG3942	CHAP domain
FGL65_RS01310	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FGL65_RS01315	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FGL65_RS01330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FGL65_RS01340	COG0318	PFAM AMP-dependent synthetase and ligase
FGL65_RS01355	COG4619	ABC transporter
FGL65_RS01360	COG0390	transport system, permease component
FGL65_RS01385	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FGL65_RS01390	COG2208	phosphoserine phosphatase activity
FGL65_RS01390	COG2770	Histidine kinase
FGL65_RS01420	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FGL65_RS01450	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FGL65_RS01460	COG0456	acetyltransferase
FGL65_RS01470	COG0571	ribonuclease III activity
FGL65_RS01475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGL65_RS01475	COG1042	CoA-binding domain protein
FGL65_RS01475	COG0045	succinate-CoA ligase (ADP-forming) activity
FGL65_RS01480	COG0857	belongs to the CobB CobQ family
FGL65_RS01505	COG4191	Histidine kinase
FGL65_RS01515	COG1846	Transcriptional regulator
FGL65_RS01640	COG0471	metal ion transport
FGL65_RS01650	COG2200	EAL domain
FGL65_RS01655	COG0346	lactoylglutathione lyase activity
FGL65_RS01665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FGL65_RS01685	COG0438	transferase activity, transferring glycosyl groups
FGL65_RS01730	COG0720	synthase
FGL65_RS01735	COG1490	D-aminoacyl-tRNA deacylase activity
FGL65_RS01740	COG0606	chelatase, subunit chli
FGL65_RS01790	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FGL65_RS01795	COG1067	ATP-dependent peptidase activity
FGL65_RS01810	COG1494	fructose-1,6-bisphosphatase
FGL65_RS01820	COG0698	ribose 5-phosphate isomerase
FGL65_RS01840	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FGL65_RS01845	COG1410	methionine synthase
FGL65_RS01845	COG0646	methionine synthase
FGL65_RS01850	COG3118	belongs to the thioredoxin family
FGL65_RS01855	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FGL65_RS01870	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FGL65_RS01870	COG2199	diguanylate cyclase activity
FGL65_RS01880	COG1917	Cupin 2, conserved barrel domain protein
FGL65_RS01880	COG2207	Transcriptional regulator
FGL65_RS01900	COG1294	oxidase, subunit
FGL65_RS01905	COG1271	oxidase subunit
FGL65_RS01920	COG0438	transferase activity, transferring glycosyl groups
FGL65_RS01925	COG0004	ammonium transporteR
FGL65_RS01955	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FGL65_RS01960	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FGL65_RS01965	COG0071	Belongs to the small heat shock protein (HSP20) family
FGL65_RS01990	COG0326	Molecular chaperone. Has ATPase activity
FGL65_RS01995	COG3279	Response regulator of the LytR AlgR family
FGL65_RS02000	COG3275	phosphorelay sensor kinase activity
FGL65_RS02005	COG1966	Carbon starvation protein
FGL65_RS02045	COG1090	epimerase
FGL65_RS02050	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FGL65_RS02060	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FGL65_RS02075	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FGL65_RS02080	COG0438	transferase activity, transferring glycosyl groups
FGL65_RS02085	COG0367	asparagine synthase
FGL65_RS02140	COG2204	response regulator
FGL65_RS02145	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FGL65_RS02155	COG2193	ferroxidase activity
FGL65_RS02165	COG2239	Acts as a magnesium transporter
FGL65_RS02190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGL65_RS02200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FGL65_RS02210	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FGL65_RS02215	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FGL65_RS02220	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FGL65_RS02225	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FGL65_RS02235	COG0295	cytidine deaminase activity
FGL65_RS02240	COG1079	Belongs to the binding-protein-dependent transport system permease family
FGL65_RS02245	COG4603	Belongs to the binding-protein-dependent transport system permease family
FGL65_RS02250	COG3845	ABC transporter
FGL65_RS02255	COG1744	ABC transporter substrate-binding protein PnrA-like
FGL65_RS02260	COG0243	molybdopterin cofactor binding
FGL65_RS02265	COG0438	transferase activity, transferring glycosyl groups
FGL65_RS02335	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FGL65_RS02340	COG0540	Belongs to the ATCase OTCase family
FGL65_RS02360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGL65_RS02365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGL65_RS02370	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FGL65_RS02380	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FGL65_RS02400	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FGL65_RS02405	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FGL65_RS02410	COG2226	methyltransferase
FGL65_RS02420	COG2089	acid synthase
FGL65_RS02440	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FGL65_RS02450	COG1083	cytidylyl-transferase
FGL65_RS02480	COG3980	spore coat polysaccharide biosynthesis protein
FGL65_RS02485	COG0367	asparagine synthase
FGL65_RS02490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FGL65_RS02490	COG0519	Catalyzes the synthesis of GMP from XMP
FGL65_RS02495	COG1216	Glycosyl transferase, family 2
FGL65_RS02535	COG0367	asparagine synthase
FGL65_RS02555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGL65_RS02565	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FGL65_RS02565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FGL65_RS02585	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FGL65_RS02590	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FGL65_RS02590	COG0512	Glutamine amidotransferase of anthranilate synthase
FGL65_RS02600	COG0644	oxidoreductase
FGL65_RS02605	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FGL65_RS02605	COG0519	Catalyzes the synthesis of GMP from XMP
FGL65_RS02615	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FGL65_RS02625	COG0187	DNA topoisomerase II activity
FGL65_RS02630	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FGL65_RS02645	COG3655	Transcriptional regulator
FGL65_RS02725	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FGL65_RS02740	COG0330	HflC and HflK could
FGL65_RS02750	COG1192	Involved in chromosome partitioning
FGL65_RS02760	COG1475	DNA binding
FGL65_RS02765	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FGL65_RS02765	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FGL65_RS02795	COG0534	Mate efflux family protein
FGL65_RS02800	COG1606	tRNA processing
FGL65_RS02805	COG1691	(AIR) carboxylase
FGL65_RS02810	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FGL65_RS02815	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
FGL65_RS02825	COG1136	(ABC) transporter
FGL65_RS02825	COG0577	efflux transmembrane transporter activity
FGL65_RS02850	COG1309	transcriptional regulator
FGL65_RS02865	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FGL65_RS02880	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FGL65_RS02895	COG3706	GGDEF domain
FGL65_RS02905	COG1215	transferase activity, transferring glycosyl groups
FGL65_RS02910	COG0784	Response regulator, receiver
FGL65_RS02910	COG2205	protein histidine kinase activity
FGL65_RS02920	COG2205	protein histidine kinase activity
FGL65_RS02925	COG2202	Pas domain
FGL65_RS02925	COG2205	protein histidine kinase activity
FGL65_RS02930	COG1454	alcohol dehydrogenase
FGL65_RS02935	COG2198	Histidine kinase
FGL65_RS02935	COG5002	protein histidine kinase activity
FGL65_RS02935	COG0784	Response regulator, receiver
FGL65_RS02940	COG1151	hydroxylamine reductase activity
FGL65_RS02950	COG0018	arginyl-trna synthetase
FGL65_RS02955	COG0440	acetolactate synthase activity
FGL65_RS02960	COG0280	phosphate acetyltransferase
FGL65_RS02965	COG3426	butyrate kinase activity
FGL65_RS02970	COG2205	protein histidine kinase activity
FGL65_RS02970	COG0784	Response regulator, receiver
FGL65_RS02995	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FGL65_RS03020	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FGL65_RS03075	COG0517	IMP dehydrogenase activity
FGL65_RS03080	COG0280	phosphate acetyltransferase
FGL65_RS03085	COG2205	protein histidine kinase activity
FGL65_RS03085	COG0784	Response regulator, receiver
FGL65_RS03105	COG0071	Belongs to the small heat shock protein (HSP20) family
FGL65_RS03110	COG2835	tetraacyldisaccharide 4'-kinase activity
FGL65_RS03115	COG0784	Response regulator, receiver
FGL65_RS03115	COG0835	chemotaxis
FGL65_RS03120	COG0587	DNA-directed DNA polymerase activity
FGL65_RS03135	COG1739	Uncharacterized protein family UPF0029
FGL65_RS03140	COG1966	Carbon starvation protein
FGL65_RS03155	COG0697	spore germination
FGL65_RS03160	COG0586	Pfam SNARE associated Golgi protein
FGL65_RS03175	COG1136	(ABC) transporter
FGL65_RS03195	COG1309	transcriptional regulator
FGL65_RS03215	COG2169	Transcriptional regulator
FGL65_RS03215	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FGL65_RS03220	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FGL65_RS03225	COG0513	Belongs to the DEAD box helicase family
FGL65_RS03245	COG1584	GPR1 FUN34 yaaH family protein
FGL65_RS03250	COG0693	protein deglycase activity
FGL65_RS03265	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FGL65_RS03310	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FGL65_RS03310	COG4106	trans-aconitate 2-methyltransferase activity
FGL65_RS03330	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FGL65_RS03370	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FGL65_RS03380	COG3437	response regulator, receiver
FGL65_RS03380	COG2770	Histidine kinase
FGL65_RS03385	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
FGL65_RS03390	COG0352	thiamine-phosphate diphosphorylase activity
FGL65_RS03395	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FGL65_RS03405	COG5002	protein histidine kinase activity
FGL65_RS03405	COG0784	Response regulator, receiver
FGL65_RS03410	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FGL65_RS03415	COG0840	transmembrane signaling receptor activity
FGL65_RS03420	COG0826	peptidase U32
FGL65_RS03435	COG0517	IMP dehydrogenase activity
FGL65_RS03440	COG1073	alpha beta
FGL65_RS03565	COG2204	response regulator
FGL65_RS03585	COG4964	Belongs to the GSP D family
FGL65_RS03645	COG5000	phosphorelay sensor kinase activity
FGL65_RS03665	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FGL65_RS03670	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FGL65_RS03685	COG2201	protein-glutamate methylesterase activity
FGL65_RS03700	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FGL65_RS03705	COG1830	Aldolase
FGL65_RS03760	COG2853	Lipoprotein
FGL65_RS03765	COG0708	Exodeoxyribonuclease III
FGL65_RS03770	COG2081	HI0933 family
FGL65_RS03790	COG1120	ATPase activity
FGL65_RS03795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGL65_RS03805	COG0697	spore germination
FGL65_RS03815	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FGL65_RS03905	COG0438	transferase activity, transferring glycosyl groups
FGL65_RS03970	COG1366	Belongs to the anti-sigma-factor antagonist family
FGL65_RS03995	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FGL65_RS04015	COG0006	proline dipeptidase activity
FGL65_RS04030	COG0573	inorganic phosphate transmembrane transporter activity
FGL65_RS04035	COG0581	inorganic phosphate transmembrane transporter activity
FGL65_RS04040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGL65_RS04060	COG0686	Belongs to the AlaDH PNT family
FGL65_RS04070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGL65_RS04075	COG0577	efflux transmembrane transporter activity
FGL65_RS04075	COG1136	(ABC) transporter
FGL65_RS04080	COG1136	(ABC) transporter
FGL65_RS04080	COG0577	efflux transmembrane transporter activity
FGL65_RS04095	COG0697	spore germination
FGL65_RS04105	COG0784	Response regulator, receiver
FGL65_RS04105	COG5002	protein histidine kinase activity
FGL65_RS04120	COG0860	N-Acetylmuramoyl-L-alanine amidase
FGL65_RS04130	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FGL65_RS04135	COG2964	Protein conserved in bacteria
FGL65_RS04140	COG0251	oxidation-reduction process
FGL65_RS04145	COG1301	dicarboxylic acid transport
FGL65_RS04150	COG3681	Belongs to the UPF0597 family
FGL65_RS04155	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FGL65_RS04160	COG1757	Na H antiporter
FGL65_RS04170	COG1242	4 iron, 4 sulfur cluster binding
FGL65_RS04175	COG1077	Cell shape determining protein MreB Mrl
FGL65_RS04190	COG0768	penicillin binding
FGL65_RS04195	COG0772	Belongs to the SEDS family
FGL65_RS04210	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FGL65_RS04215	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FGL65_RS04220	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FGL65_RS04225	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FGL65_RS04230	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FGL65_RS04240	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FGL65_RS04255	COG1418	mRNA catabolic process
FGL65_RS04265	COG1692	metallophosphoesterase
FGL65_RS04270	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FGL65_RS04275	COG0438	transferase activity, transferring glycosyl groups
FGL65_RS04280	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FGL65_RS04285	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FGL65_RS04290	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FGL65_RS04295	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FGL65_RS04310	COG0589	response to stress
FGL65_RS04320	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FGL65_RS04325	COG0109	protoheme IX farnesyltransferase activity
FGL65_RS04330	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FGL65_RS04330	COG3264	Mechanosensitive ion channel
FGL65_RS04350	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FGL65_RS04360	COG0148	phosphopyruvate hydratase activity
FGL65_RS04375	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FGL65_RS04380	COG0436	Aminotransferase
FGL65_RS04390	COG0583	DNA-binding transcription factor activity
FGL65_RS04405	COG0583	DNA-binding transcription factor activity
FGL65_RS04410	COG0583	DNA-binding transcription factor activity
FGL65_RS04420	COG0151	Belongs to the GarS family
FGL65_RS04425	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FGL65_RS04435	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FGL65_RS04440	COG3279	Response regulator of the LytR AlgR family
FGL65_RS04450	COG2814	Major facilitator Superfamily
FGL65_RS04455	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FGL65_RS04460	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FGL65_RS04465	COG2205	protein histidine kinase activity
FGL65_RS04485	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FGL65_RS04510	COG2192	nodulation
FGL65_RS04515	COG5002	protein histidine kinase activity
FGL65_RS04525	COG1309	transcriptional regulator
FGL65_RS04535	COG0560	Phosphoserine phosphatase
FGL65_RS04535	COG3830	Belongs to the UPF0237 family
FGL65_RS04545	COG0701	Predicted permease
FGL65_RS04550	COG1104	cysteine desulfurase activity
FGL65_RS04555	COG5002	protein histidine kinase activity
FGL65_RS04560	COG0628	permease
FGL65_RS04570	COG0840	transmembrane signaling receptor activity
FGL65_RS04585	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FGL65_RS04595	COG0598	Magnesium transport protein CorA
FGL65_RS04600	COG0668	transmembrane transport
FGL65_RS04605	COG1360	Flagellar Motor Protein
FGL65_RS04610	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FGL65_RS04630	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FGL65_RS04640	COG0330	HflC and HflK could
FGL65_RS04645	COG0330	HflC and HflK could
FGL65_RS04660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGL65_RS04665	COG0577	efflux transmembrane transporter activity
FGL65_RS04665	COG1136	(ABC) transporter
FGL65_RS04670	COG1136	(ABC) transporter
FGL65_RS04670	COG0577	efflux transmembrane transporter activity
FGL65_RS04680	COG0481	GTPase activity
FGL65_RS04700	COG0640	Transcriptional regulator
FGL65_RS04720	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FGL65_RS04740	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FGL65_RS04750	COG0537	adenosine 5'-monophosphoramidase activity
FGL65_RS04755	COG0776	regulation of translation
FGL65_RS04765	COG2177	Part of the ABC transporter FtsEX involved in
FGL65_RS04770	COG2884	Cell division ATP-binding protein ftsE
FGL65_RS04775	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FGL65_RS04785	COG0328	RNA-DNA hybrid ribonuclease activity
FGL65_RS04805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FGL65_RS04815	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FGL65_RS04850	COG1136	(ABC) transporter
FGL65_RS04885	COG1530	ribonuclease E activity
FGL65_RS04890	COG0731	radical SAM domain protein
FGL65_RS04890	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FGL65_RS04905	COG4977	sequence-specific DNA binding
FGL65_RS04940	COG3706	GGDEF domain
FGL65_RS04945	COG0346	lactoylglutathione lyase activity
FGL65_RS04950	COG2205	protein histidine kinase activity
FGL65_RS04950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGL65_RS04960	COG0784	Response regulator, receiver
FGL65_RS04960	COG2205	protein histidine kinase activity
FGL65_RS04965	COG1489	DNA binding
FGL65_RS04975	COG1607	acyl-coa hydrolase
FGL65_RS04985	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FGL65_RS04985	COG0116	Belongs to the methyltransferase superfamily
FGL65_RS05010	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FGL65_RS05015	COG1268	BioY protein
FGL65_RS05025	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGL65_RS05035	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FGL65_RS05045	COG2414	aldehyde ferredoxin oxidoreductase
FGL65_RS05050	COG0251	oxidation-reduction process
FGL65_RS05065	COG0166	Belongs to the GPI family
FGL65_RS05070	COG4191	Histidine kinase
FGL65_RS05075	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FGL65_RS05080	COG3852	Histidine kinase
FGL65_RS05090	COG0277	FAD linked oxidase domain protein
FGL65_RS05095	COG2814	Major facilitator Superfamily
FGL65_RS05125	COG0653	protein targeting
FGL65_RS05135	COG0189	ligase activity
FGL65_RS05135	COG4067	protein conserved in archaea
FGL65_RS05140	COG0189	ligase activity
FGL65_RS05160	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FGL65_RS05170	COG1205	dead DEAH box helicase
FGL65_RS05170	COG1111	helicase
FGL65_RS05185	COG2204	response regulator
FGL65_RS05195	COG0515	serine threonine protein kinase
FGL65_RS05195	COG2815	serine threonine protein kinase
FGL65_RS05210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FGL65_RS05215	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FGL65_RS05220	COG1671	Belongs to the UPF0178 family
FGL65_RS05235	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FGL65_RS05250	COG1058	Belongs to the CinA family
FGL65_RS05250	COG1546	Belongs to the CinA family
FGL65_RS05255	COG1328	CTP reductase activity
FGL65_RS05255	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FGL65_RS05265	COG1328	CTP reductase activity
FGL65_RS05265	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FGL65_RS05300	COG2226	methyltransferase
FGL65_RS05320	COG0142	geranyltranstransferase activity
FGL65_RS05325	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FGL65_RS05335	COG0840	transmembrane signaling receptor activity
FGL65_RS05345	COG1592	Rubrerythrin
FGL65_RS05350	COG2033	superoxide reductase activity
FGL65_RS05355	COG1773	rubredoxin
FGL65_RS05370	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FGL65_RS05375	COG1127	ABC transporter
FGL65_RS05390	COG2853	Lipoprotein
FGL65_RS05400	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FGL65_RS05410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FGL65_RS05430	COG2046	Belongs to the sulfate adenylyltransferase family
FGL65_RS05445	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FGL65_RS05450	COG2081	HI0933 family
FGL65_RS05490	COG2205	protein histidine kinase activity
FGL65_RS05490	COG0784	Response regulator, receiver
FGL65_RS05500	COG1522	sequence-specific DNA binding
FGL65_RS05505	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FGL65_RS05545	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FGL65_RS05555	COG2135	peptidase activity
FGL65_RS05560	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FGL65_RS05565	COG0228	four-way junction DNA binding
FGL65_RS05570	COG1837	Belongs to the UPF0109 family
FGL65_RS05575	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FGL65_RS05580	COG0336	Belongs to the RNA methyltransferase TrmD family
FGL65_RS05580	COG4752	Belongs to the RNA methyltransferase TrmD family
FGL65_RS05585	COG0335	large ribosomal subunit rRNA binding
FGL65_RS05615	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FGL65_RS05620	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FGL65_RS05625	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FGL65_RS05640	COG5002	protein histidine kinase activity
FGL65_RS05655	COG0375	protein maturation
FGL65_RS05660	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FGL65_RS05680	COG0489	protein tyrosine kinase activity
FGL65_RS05685	COG0348	domain, Protein
FGL65_RS05705	COG1115	amino acid carrier protein
FGL65_RS05710	COG0686	Belongs to the AlaDH PNT family
FGL65_RS05720	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FGL65_RS05760	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FGL65_RS05770	COG1215	transferase activity, transferring glycosyl groups
FGL65_RS05785	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FGL65_RS05810	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FGL65_RS05835	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FGL65_RS05860	COG0668	transmembrane transport
FGL65_RS05865	COG0179	Fumarylacetoacetate (FAA) hydrolase
FGL65_RS05880	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FGL65_RS05905	COG4134	Bacterial extracellular solute-binding protein
FGL65_RS05910	COG0133	tryptophan synthase activity
FGL65_RS05940	COG2731	YhcH YjgK YiaL family protein
FGL65_RS05945	COG0778	Nitroreductase
FGL65_RS05950	COG1162	GTPase activity
FGL65_RS06010	COG3829	transcription factor binding
FGL65_RS06010	COG3290	protein histidine kinase activity
FGL65_RS06035	COG4191	Histidine kinase
FGL65_RS06040	COG2204	response regulator
FGL65_RS06045	COG1414	Transcriptional regulator
FGL65_RS06060	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGL65_RS06085	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FGL65_RS06090	COG2076	Multidrug Resistance protein
FGL65_RS06100	COG2184	nucleotidyltransferase activity
FGL65_RS06175	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
FGL65_RS06180	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FGL65_RS06215	COG4191	Histidine kinase
FGL65_RS06225	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FGL65_RS06230	COG2205	protein histidine kinase activity
FGL65_RS06230	COG0784	Response regulator, receiver
FGL65_RS06260	COG0746	molybdenum cofactor guanylyltransferase activity
FGL65_RS06270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGL65_RS06270	COG0045	succinate-CoA ligase (ADP-forming) activity
FGL65_RS06270	COG1042	CoA-binding domain protein
FGL65_RS06285	COG3033	Beta-eliminating lyase
FGL65_RS06290	COG0733	neurotransmitter:sodium symporter activity
FGL65_RS06300	COG0251	oxidation-reduction process
FGL65_RS06340	COG2204	response regulator
FGL65_RS06360	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FGL65_RS06360	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FGL65_RS06365	COG1760	l-serine dehydratase
FGL65_RS06370	COG1760	l-serine dehydratase
FGL65_RS06390	COG0459	protein refolding
FGL65_RS06395	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FGL65_RS06415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FGL65_RS06420	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FGL65_RS06460	COG3104	oligopeptide transport
FGL65_RS06480	COG0492	ferredoxin-NADP+ reductase activity
FGL65_RS06490	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FGL65_RS06495	COG4978	Transcriptional regulator
FGL65_RS06495	COG0789	Transcriptional regulator
FGL65_RS06515	COG1012	belongs to the aldehyde dehydrogenase family
FGL65_RS06515	COG1454	alcohol dehydrogenase
FGL65_RS06520	COG1882	Formate acetyltransferase
FGL65_RS06525	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FGL65_RS06535	COG1454	alcohol dehydrogenase
FGL65_RS06535	COG1012	belongs to the aldehyde dehydrogenase family
FGL65_RS06545	COG4869	propanediol catabolic process
FGL65_RS06560	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
FGL65_RS06585	COG4656	Part of a membrane complex involved in electron transport
FGL65_RS06615	COG2376	Dihydroxyacetone kinase
FGL65_RS06620	COG1461	Dihydroxyacetone kinase
FGL65_RS06625	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FGL65_RS06630	COG0745	RESPONSE REGULATOR receiver
FGL65_RS06635	COG4191	Histidine kinase
FGL65_RS06650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGL65_RS06670	COG1132	(ABC) transporter
FGL65_RS06695	COG0494	nUDIX hydrolase
FGL65_RS06705	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FGL65_RS06745	COG4106	trans-aconitate 2-methyltransferase activity
FGL65_RS06765	COG0837	glucose binding
FGL65_RS06770	COG1879	ABC-type sugar transport system periplasmic component
FGL65_RS06775	COG4214	carbohydrate transport
FGL65_RS06785	COG4213	ABC transporter substrate-binding protein
FGL65_RS06790	COG1940	carbohydrate kinase activity
FGL65_RS06795	COG1454	alcohol dehydrogenase
FGL65_RS06805	COG3852	Histidine kinase
FGL65_RS06815	COG1803	Methylglyoxal synthase
FGL65_RS06860	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FGL65_RS06870	COG0303	'Molybdopterin
FGL65_RS06890	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FGL65_RS06890	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FGL65_RS06930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FGL65_RS06960	COG1994	Peptidase M50
FGL65_RS06965	COG0180	Tryptophanyl-tRNA synthetase
FGL65_RS06970	COG1047	Peptidyl-prolyl cis-trans
FGL65_RS06975	COG0436	Aminotransferase
FGL65_RS06980	COG2204	response regulator
FGL65_RS06990	COG0037	tRNA processing
FGL65_RS06995	COG1215	transferase activity, transferring glycosyl groups
FGL65_RS07005	COG0393	Putative heavy-metal-binding
FGL65_RS07020	COG0681	Belongs to the peptidase S26 family
FGL65_RS07030	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FGL65_RS07035	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FGL65_RS07050	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FGL65_RS07070	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FGL65_RS07075	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
FGL65_RS07080	COG1119	ATPase activity
FGL65_RS07085	COG1278	Cold shock
FGL65_RS07115	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FGL65_RS07120	COG0673	inositol 2-dehydrogenase activity
FGL65_RS07135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGL65_RS07140	COG0038	chloride channel
FGL65_RS07150	COG4783	chaperone-mediated protein folding
FGL65_RS07155	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FGL65_RS07165	COG0193	aminoacyl-tRNA hydrolase activity
FGL65_RS07170	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FGL65_RS07175	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FGL65_RS07190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FGL65_RS07220	COG1720	tRNA m6t6A37 methyltransferase activity
FGL65_RS07230	COG0733	neurotransmitter:sodium symporter activity
FGL65_RS07240	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FGL65_RS07255	COG1063	alcohol dehydrogenase
FGL65_RS07260	COG0438	transferase activity, transferring glycosyl groups
FGL65_RS07260	COG1216	Glycosyl transferase, family 2
FGL65_RS07265	COG4948	Mandelate Racemase Muconate Lactonizing
FGL65_RS07270	COG4608	Belongs to the ABC transporter superfamily
FGL65_RS07275	COG0444	Belongs to the ABC transporter superfamily
FGL65_RS07280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGL65_RS07285	COG0601	transmembrane transport
FGL65_RS07290	COG0747	negative chemotaxis
FGL65_RS07295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FGL65_RS07305	COG1522	sequence-specific DNA binding
FGL65_RS07320	COG0840	transmembrane signaling receptor activity
FGL65_RS07325	COG0840	transmembrane signaling receptor activity
FGL65_RS07335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGL65_RS07340	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FGL65_RS07350	COG1794	racemase activity, acting on amino acids and derivatives
FGL65_RS07355	COG0318	PFAM AMP-dependent synthetase and ligase
FGL65_RS07420	COG2855	membrane
FGL65_RS07430	COG2204	response regulator
FGL65_RS07465	COG1215	transferase activity, transferring glycosyl groups
FGL65_RS07465	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FGL65_RS07485	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FGL65_RS07490	COG0217	transcriptional regulatory protein
FGL65_RS07495	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FGL65_RS07500	COG0632	four-way junction helicase activity
FGL65_RS07510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FGL65_RS07535	COG2205	protein histidine kinase activity
FGL65_RS07600	COG0432	Pfam Uncharacterised protein family UPF0047
FGL65_RS07630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGL65_RS07635	COG0601	transmembrane transport
FGL65_RS07645	COG1733	regulation of RNA biosynthetic process
FGL65_RS07690	COG3706	GGDEF domain
FGL65_RS07700	COG1404	Belongs to the peptidase S8 family
FGL65_RS07705	COG2195	Cleaves the N-terminal amino acid of tripeptides
FGL65_RS07715	COG1408	metallophosphoesterase
FGL65_RS07725	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FGL65_RS07740	COG2814	Major facilitator Superfamily
FGL65_RS07745	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FGL65_RS07750	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FGL65_RS07755	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FGL65_RS07760	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FGL65_RS07770	COG1040	competence protein
FGL65_RS07780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FGL65_RS07790	COG1595	DNA-templated transcription, initiation
FGL65_RS07815	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FGL65_RS07820	COG3153	acetyltransferase
FGL65_RS07835	COG2095	MarC family integral membrane protein
FGL65_RS07840	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FGL65_RS07855	COG3829	transcription factor binding
FGL65_RS07870	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FGL65_RS07880	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FGL65_RS07885	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FGL65_RS07885	COG3608	succinylglutamate desuccinylase aspartoacylase
FGL65_RS07890	COG0402	S-adenosylhomocysteine deaminase activity
FGL65_RS07895	COG2252	PERMEase
FGL65_RS07900	COG2233	PERMEase
FGL65_RS07905	COG2233	PERMEase
FGL65_RS07910	COG2080	2 iron, 2 sulfur cluster binding
FGL65_RS07915	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FGL65_RS07920	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FGL65_RS07925	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FGL65_RS07925	COG3608	succinylglutamate desuccinylase aspartoacylase
FGL65_RS07935	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FGL65_RS07935	COG2080	2 iron, 2 sulfur cluster binding
FGL65_RS07940	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FGL65_RS07945	COG0493	'glutamate synthase
FGL65_RS07945	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FGL65_RS07955	COG0402	S-adenosylhomocysteine deaminase activity
FGL65_RS07965	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FGL65_RS07970	COG0549	Belongs to the carbamate kinase family
FGL65_RS07975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FGL65_RS07980	COG0497	DNA recombination
FGL65_RS07985	COG1247	-acetyltransferase
FGL65_RS07990	COG0456	acetyltransferase
FGL65_RS07995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGL65_RS08000	COG0601	transmembrane transport
FGL65_RS08015	COG1280	lysine exporter protein (LysE YggA)
FGL65_RS08040	COG4771	TonB-dependent receptor
FGL65_RS08050	COG1132	(ABC) transporter
FGL65_RS08055	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FGL65_RS08070	COG4771	TonB-dependent receptor
FGL65_RS08075	COG2223	nitrite transmembrane transporter activity
FGL65_RS08115	COG1309	transcriptional regulator
FGL65_RS08120	COG0840	transmembrane signaling receptor activity
FGL65_RS08135	COG4191	Histidine kinase
FGL65_RS08140	COG2204	response regulator
FGL65_RS08155	COG2204	response regulator
FGL65_RS08165	COG0471	metal ion transport
FGL65_RS08170	COG4566	intracellular signal transduction
FGL65_RS08175	COG2204	response regulator
FGL65_RS08185	COG3852	Histidine kinase
FGL65_RS08200	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
FGL65_RS08225	COG0535	radical SAM domain protein
FGL65_RS08225	COG1433	Dinitrogenase iron-molybdenum cofactor
FGL65_RS08250	COG0535	radical SAM domain protein
FGL65_RS08250	COG1433	Dinitrogenase iron-molybdenum cofactor
FGL65_RS08280	COG0445	tRNA wobble uridine modification
FGL65_RS08295	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FGL65_RS08310	COG2345	Transcriptional regulator
FGL65_RS08315	COG4771	TonB-dependent receptor
FGL65_RS08320	COG4977	sequence-specific DNA binding
FGL65_RS08335	COG0848	biopolymer transport protein
FGL65_RS08340	COG0811	peptide transport
FGL65_RS08345	COG0811	peptide transport
FGL65_RS08365	COG0297	glycogen (starch) synthase activity
FGL65_RS08385	COG0437	4 iron, 4 sulfur cluster binding
FGL65_RS08390	COG0243	molybdopterin cofactor binding
FGL65_RS08390	COG3383	formate dehydrogenase (NAD+) activity
FGL65_RS08395	COG0437	4 iron, 4 sulfur cluster binding
FGL65_RS08420	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FGL65_RS08445	COG4145	pantothenate transmembrane transporter activity
FGL65_RS08480	COG3695	enzyme binding
FGL65_RS08495	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FGL65_RS08500	COG1085	galactose-1-phosphate uridylyltransferase
FGL65_RS08505	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FGL65_RS08510	COG1609	Transcriptional regulator
FGL65_RS08520	COG3842	ATPase activity
FGL65_RS08535	COG0395	ABC-type sugar transport system, permease component
FGL65_RS08540	COG0513	Belongs to the DEAD box helicase family
FGL65_RS08545	COG0724	RNA recognition motif
FGL65_RS08575	COG0784	Response regulator, receiver
FGL65_RS08575	COG2205	protein histidine kinase activity
FGL65_RS08580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGL65_RS08590	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
FGL65_RS08595	COG0840	transmembrane signaling receptor activity
FGL65_RS08600	COG1446	asparaginase
FGL65_RS08605	COG2962	Rard protein
FGL65_RS08610	COG0724	RNA recognition motif
FGL65_RS08615	COG4999	Histidine kinase
FGL65_RS08615	COG3850	Histidine kinase
FGL65_RS08615	COG3437	response regulator, receiver
FGL65_RS08615	COG2205	protein histidine kinase activity
FGL65_RS08620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGL65_RS08625	COG0765	amino acid transport
FGL65_RS08635	COG0840	transmembrane signaling receptor activity
FGL65_RS08660	COG0859	PFAM glycosyl transferase family 9
FGL65_RS08690	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FGL65_RS08710	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FGL65_RS08715	COG0778	Nitroreductase
FGL65_RS08745	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FGL65_RS08755	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FGL65_RS08765	COG0859	PFAM glycosyl transferase family 9
FGL65_RS08770	COG1253	flavin adenine dinucleotide binding
FGL65_RS08775	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FGL65_RS08780	COG1138	Cytochrome C-type biogenesis protein
FGL65_RS08790	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FGL65_RS08795	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FGL65_RS08835	COG0517	IMP dehydrogenase activity
FGL65_RS08835	COG0516	GMP reductase activity
FGL65_RS08840	COG0519	Catalyzes the synthesis of GMP from XMP
FGL65_RS08845	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FGL65_RS08850	COG0805	protein transport
FGL65_RS08855	COG0131	Imidazoleglycerol-phosphate dehydratase
FGL65_RS08865	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FGL65_RS08870	COG0463	Glycosyl transferase, family 2
FGL65_RS08875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGL65_RS08880	COG1757	Na H antiporter
FGL65_RS08885	COG0668	transmembrane transport
FGL65_RS08895	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FGL65_RS08900	COG0564	pseudouridine synthase activity
FGL65_RS08915	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
FGL65_RS08935	COG0542	response to heat
FGL65_RS08940	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FGL65_RS08945	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FGL65_RS08955	COG2226	methyltransferase
FGL65_RS08965	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FGL65_RS08975	COG0521	Mo-molybdopterin cofactor biosynthetic process
FGL65_RS08975	COG0315	cyclic pyranopterin monophosphate synthase activity
FGL65_RS08985	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FGL65_RS08990	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FGL65_RS09015	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FGL65_RS09020	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FGL65_RS09025	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FGL65_RS09035	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FGL65_RS09045	COG1027	Aspartate ammonia-lyase
FGL65_RS09065	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FGL65_RS09065	COG4624	Iron only hydrogenase large subunit, C-terminal domain
FGL65_RS09070	COG0429	hydrolase of the alpha beta-hydrolase fold
FGL65_RS09080	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FGL65_RS09085	COG0443	Heat shock 70 kDa protein
FGL65_RS09100	COG0154	amidase activity
FGL65_RS09115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FGL65_RS09115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FGL65_RS09120	COG0450	alkyl hydroperoxide reductase
FGL65_RS09130	COG0482	sulfurtransferase activity
FGL65_RS09140	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FGL65_RS09145	COG1561	YicC-like family, N-terminal region
FGL65_RS09150	COG2052	Domain of unknown function (DUF370)
FGL65_RS09155	COG0194	GDP metabolic process
FGL65_RS09160	COG0284	orotidine-5'-phosphate decarboxylase activity
FGL65_RS09175	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FGL65_RS09190	COG0436	Aminotransferase
FGL65_RS09210	COG4166	transmembrane transport
FGL65_RS09230	COG0583	DNA-binding transcription factor activity
FGL65_RS09235	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FGL65_RS09255	COG1217	gtp-binding protein TYPA
FGL65_RS09265	COG1027	Aspartate ammonia-lyase
FGL65_RS09285	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FGL65_RS09300	COG2204	response regulator
FGL65_RS09310	COG1620	l-lactate permease
FGL65_RS09315	COG0277	FAD linked oxidase domain protein
FGL65_RS09325	COG0857	belongs to the CobB CobQ family
FGL65_RS09325	COG0280	phosphate acetyltransferase
FGL65_RS09330	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FGL65_RS09340	COG1139	Iron-sulfur cluster binding protein
FGL65_RS09370	COG0549	Belongs to the carbamate kinase family
FGL65_RS09380	COG4974	Belongs to the 'phage' integrase family
FGL65_RS09385	COG3842	ATPase activity
FGL65_RS09395	COG4149	molybdate abc transporter
FGL65_RS09420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGL65_RS09425	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FGL65_RS09430	COG3273	potassium ion transport
FGL65_RS09430	COG0471	metal ion transport
FGL65_RS09440	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FGL65_RS09445	COG2204	response regulator
FGL65_RS09470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGL65_RS09515	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FGL65_RS09520	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FGL65_RS09525	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FGL65_RS09535	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FGL65_RS09540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGL65_RS09540	COG0072	phenylalanine-tRNA ligase activity
FGL65_RS09545	COG2113	Glycine betaine
FGL65_RS09550	COG4176	ABC-type proline glycine betaine transport system permease component
FGL65_RS09555	COG4175	Glycine betaine
FGL65_RS09560	COG1454	alcohol dehydrogenase
FGL65_RS09565	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FGL65_RS09595	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FGL65_RS09600	COG1157	protein secretion by the type III secretion system
FGL65_RS09610	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FGL65_RS09620	COG1677	Flagellar hook-basal body complex protein FliE
FGL65_RS09630	COG1815	bacterial-type flagellum-dependent cell motility
FGL65_RS09650	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FGL65_RS09655	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FGL65_RS09665	COG0138	bifunctional purine biosynthesis protein purh
FGL65_RS09670	COG0840	transmembrane signaling receptor activity
FGL65_RS09680	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FGL65_RS09720	COG0840	transmembrane signaling receptor activity
FGL65_RS09750	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FGL65_RS09760	COG0306	phosphate transporter
FGL65_RS09765	COG1392	Phosphate transport regulator
FGL65_RS09780	COG2954	triphosphatase activity
FGL65_RS09785	COG0583	DNA-binding transcription factor activity
FGL65_RS09795	COG2274	protein secretion by the type I secretion system
FGL65_RS09800	COG2994	toxin metabolic process
FGL65_RS09830	COG0285	dihydrofolate synthase activity
FGL65_RS09835	COG1921	L-seryl-tRNASec selenium transferase activity
FGL65_RS09840	COG1362	aminopeptidase activity
FGL65_RS09870	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FGL65_RS09880	COG1639	'signal transduction protein
FGL65_RS09885	COG1234	tRNA 3'-trailer cleavage
FGL65_RS09895	COG0745	RESPONSE REGULATOR receiver
FGL65_RS09900	COG1774	PSP1 C-terminal conserved region
FGL65_RS09905	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGL65_RS09905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGL65_RS09915	COG3272	Protein of unknown function (DUF1722)
FGL65_RS09925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGL65_RS09930	COG0765	amino acid transport
FGL65_RS09935	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FGL65_RS09940	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FGL65_RS09945	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FGL65_RS09945	COG0517	IMP dehydrogenase activity
FGL65_RS09970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGL65_RS09975	COG0826	peptidase U32
FGL65_RS09980	COG0543	2 iron, 2 sulfur cluster binding
FGL65_RS09985	COG0167	dihydroorotate dehydrogenase activity
FGL65_RS10000	COG0385	Bile acid
FGL65_RS10020	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FGL65_RS10035	COG1054	Belongs to the UPF0176 family
FGL65_RS10060	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FGL65_RS10070	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FGL65_RS10075	COG0305	Participates in initiation and elongation during chromosome replication
FGL65_RS10080	COG0359	binds to the 23S rRNA
FGL65_RS10085	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FGL65_RS10090	COG0360	Binds together with S18 to 16S ribosomal RNA
FGL65_RS10095	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FGL65_RS10100	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FGL65_RS10150	COG0835	chemotaxis
FGL65_RS10150	COG0784	Response regulator, receiver
FGL65_RS10155	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FGL65_RS10160	COG0640	Transcriptional regulator
FGL65_RS10175	COG1702	phosphate starvation-inducible protein PhoH
FGL65_RS10180	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FGL65_RS10190	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FGL65_RS10195	COG0137	argininosuccinate synthase activity
FGL65_RS10200	COG0165	Argininosuccinate lyase
FGL65_RS10205	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FGL65_RS10210	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FGL65_RS10215	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FGL65_RS10225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FGL65_RS10230	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FGL65_RS10240	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FGL65_RS10280	COG0671	phosphoesterase, PA-phosphatase related
FGL65_RS10285	COG0438	transferase activity, transferring glycosyl groups
FGL65_RS10295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGL65_RS10295	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FGL65_RS10305	COG1304	FMN binding
FGL65_RS10310	COG0730	response to heat
FGL65_RS10315	COG2186	Transcriptional regulator
FGL65_RS10335	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FGL65_RS10340	COG4134	Bacterial extracellular solute-binding protein
FGL65_RS10345	COG4149	molybdate abc transporter
FGL65_RS10350	COG4176	ABC-type proline glycine betaine transport system permease component
FGL65_RS10355	COG0012	GTP binding
FGL65_RS10360	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FGL65_RS10370	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FGL65_RS10380	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FGL65_RS10395	COG1309	transcriptional regulator
FGL65_RS10400	COG0612	Peptidase, M16
FGL65_RS10410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGL65_RS10415	COG0446	pyridine nucleotide-disulphide oxidoreductase
FGL65_RS10420	COG3437	response regulator, receiver
FGL65_RS10420	COG2205	protein histidine kinase activity
FGL65_RS10420	COG4999	Histidine kinase
FGL65_RS10420	COG3850	Histidine kinase
FGL65_RS10425	COG1846	Transcriptional regulator
FGL65_RS10430	COG4608	Belongs to the ABC transporter superfamily
FGL65_RS10435	COG0444	Belongs to the ABC transporter superfamily
FGL65_RS10440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGL65_RS10445	COG0601	transmembrane transport
FGL65_RS10470	COG2223	nitrite transmembrane transporter activity
FGL65_RS10475	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FGL65_RS10490	COG0859	PFAM glycosyl transferase family 9
FGL65_RS10510	COG0741	lytic transglycosylase activity
FGL65_RS10520	COG1830	Aldolase
FGL65_RS10525	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FGL65_RS10565	COG1126	abc transporter atp-binding protein
FGL65_RS10570	COG0765	amino acid transport
FGL65_RS10585	COG0628	permease
FGL65_RS10590	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FGL65_RS10600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGL65_RS10605	COG2721	sulfolactate sulfo-lyase activity
FGL65_RS10610	COG2721	sulfolactate sulfo-lyase activity
FGL65_RS10705	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FGL65_RS10715	COG0521	Mo-molybdopterin cofactor biosynthetic process
FGL65_RS10730	COG0438	transferase activity, transferring glycosyl groups
FGL65_RS10740	COG0588	phosphoglycerate mutase activity
FGL65_RS10800	COG0688	phosphatidylethanolamine metabolic process
FGL65_RS10805	COG1183	phosphatidylcholine synthase activity
FGL65_RS10810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FGL65_RS10815	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FGL65_RS10820	COG0066	3-isopropylmalate dehydratase activity
FGL65_RS10825	COG0473	3-isopropylmalate dehydrogenase activity
FGL65_RS10840	COG2827	Endonuclease containing a URI domain
FGL65_RS10845	COG0488	(ABC) transporter
FGL65_RS10855	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FGL65_RS10860	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FGL65_RS10880	COG1091	dTDP-4-dehydrorhamnose reductase activity
FGL65_RS10890	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FGL65_RS10905	COG4662	Binding-protein-dependent transport system inner membrane component
FGL65_RS10910	COG2998	abc-type tungstate transport system, permease component
FGL65_RS10930	COG0840	transmembrane signaling receptor activity
FGL65_RS10955	COG4657	Part of a membrane complex involved in electron transport
FGL65_RS10960	COG4660	Part of a membrane complex involved in electron transport
FGL65_RS10970	COG4658	electron transport chain
FGL65_RS11010	COG0492	ferredoxin-NADP+ reductase activity
FGL65_RS11030	COG4999	Histidine kinase
FGL65_RS11030	COG3850	Histidine kinase
FGL65_RS11030	COG3437	response regulator, receiver
FGL65_RS11030	COG2205	protein histidine kinase activity
FGL65_RS11050	COG2920	part of a sulfur-relay system
FGL65_RS11055	COG0254	rRNA binding
FGL65_RS11060	COG3872	metal-dependent enzyme
FGL65_RS11065	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FGL65_RS11070	COG2890	protein-(glutamine-N5) methyltransferase activity
FGL65_RS11075	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FGL65_RS11105	COG1191	sigma factor activity
FGL65_RS11120	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FGL65_RS11125	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FGL65_RS11130	COG1684	flagellar biosynthetic protein fliR
FGL65_RS11135	COG0739	heme binding
FGL65_RS11140	COG0037	tRNA processing
FGL65_RS11150	COG1758	RNA polymerase activity
FGL65_RS11155	COG0484	heat shock protein binding
FGL65_RS11160	COG0315	cyclic pyranopterin monophosphate synthase activity
FGL65_RS11165	COG0107	imidazoleglycerol-phosphate synthase activity
FGL65_RS11170	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FGL65_RS11175	COG0484	heat shock protein binding
FGL65_RS11195	COG2268	Band 7 protein
FGL65_RS11210	COG4232	protein-disulfide reductase activity
FGL65_RS11245	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FGL65_RS11255	COG1136	(ABC) transporter
FGL65_RS11260	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FGL65_RS11270	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FGL65_RS11280	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FGL65_RS11285	COG3494	Protein of unknown function (DUF1009)
FGL65_RS11295	COG2894	cell division
FGL65_RS11300	COG0489	protein tyrosine kinase activity
FGL65_RS11310	COG1295	ribonuclease BN
FGL65_RS11320	COG0343	queuine tRNA-ribosyltransferase activity
FGL65_RS11325	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FGL65_RS11330	COG1324	tolerance protein
FGL65_RS11335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGL65_RS11350	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FGL65_RS11380	COG0823	Involved in the tonB-independent uptake of proteins
FGL65_RS11390	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FGL65_RS11395	COG1280	lysine exporter protein (LysE YggA)
FGL65_RS11415	COG0784	Response regulator, receiver
FGL65_RS11415	COG2205	protein histidine kinase activity
FGL65_RS11420	COG0424	maF-like protein
FGL65_RS11430	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FGL65_RS11440	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FGL65_RS11450	COG4603	Belongs to the binding-protein-dependent transport system permease family
FGL65_RS11455	COG1079	Belongs to the binding-protein-dependent transport system permease family
FGL65_RS11460	COG3845	ABC transporter
FGL65_RS11470	COG0765	amino acid transport
FGL65_RS11475	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FGL65_RS11490	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
FGL65_RS11500	COG0436	Aminotransferase
FGL65_RS11510	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FGL65_RS11515	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FGL65_RS11520	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FGL65_RS11525	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FGL65_RS11540	COG0488	(ABC) transporter
FGL65_RS11550	COG5002	protein histidine kinase activity
FGL65_RS11550	COG0784	Response regulator, receiver
FGL65_RS11550	COG2205	protein histidine kinase activity
FGL65_RS11555	COG2200	EAL domain
FGL65_RS11560	COG0825	malonyl-CoA metabolic process
FGL65_RS11565	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FGL65_RS11570	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FGL65_RS11615	COG4191	Histidine kinase
FGL65_RS11615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGL65_RS11625	COG0601	transmembrane transport
FGL65_RS11630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGL65_RS11635	COG0444	Belongs to the ABC transporter superfamily
FGL65_RS11640	COG4608	Belongs to the ABC transporter superfamily
FGL65_RS11650	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FGL65_RS11660	COG0564	pseudouridine synthase activity
FGL65_RS11685	COG0590	tRNA wobble adenosine to inosine editing
FGL65_RS11690	COG0047	phosphoribosylformylglycinamidine synthase activity
FGL65_RS11695	COG0504	CTP synthase activity
FGL65_RS11700	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FGL65_RS11705	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FGL65_RS11720	COG1137	ATPase activity
FGL65_RS11725	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FGL65_RS11735	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGL65_RS11740	COG1660	Displays ATPase and GTPase activities
FGL65_RS11750	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGL65_RS11760	COG1227	inorganic diphosphatase activity
FGL65_RS11770	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGL65_RS11780	COG0776	regulation of translation
FGL65_RS11790	COG3706	GGDEF domain
FGL65_RS11795	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FGL65_RS11800	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FGL65_RS11805	COG4535	Mg2 and Co2 transporter CorC
FGL65_RS11810	COG0445	tRNA wobble uridine modification
FGL65_RS11815	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FGL65_RS11825	COG0402	S-adenosylhomocysteine deaminase activity
FGL65_RS11830	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FGL65_RS11835	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FGL65_RS11840	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FGL65_RS11845	COG0776	regulation of translation
FGL65_RS11850	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FGL65_RS11855	COG1610	YqeY-like protein
FGL65_RS11860	COG1193	negative regulation of DNA recombination
FGL65_RS11865	COG0358	DNA primase activity
FGL65_RS11875	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FGL65_RS11880	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FGL65_RS11885	COG0105	UTP biosynthetic process
FGL65_RS11890	COG1116	anion transmembrane transporter activity
FGL65_RS11890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FGL65_RS11895	COG4120	Belongs to the binding-protein-dependent transport system permease family
FGL65_RS11915	COG0793	Belongs to the peptidase S41A family
FGL65_RS11925	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FGL65_RS11930	COG2264	protein methyltransferase activity
FGL65_RS11940	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FGL65_RS11965	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FGL65_RS11970	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FGL65_RS11970	COG2146	nitrite reductase [NAD(P)H] activity
FGL65_RS11975	COG0067	glutamate synthase
FGL65_RS11985	COG1862	Preprotein translocase
FGL65_RS11990	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FGL65_RS11995	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FGL65_RS12005	COG1881	PFAM PEBP family protein
FGL65_RS12010	COG0563	adenylate kinase activity
FGL65_RS12015	COG0037	tRNA processing
FGL65_RS12025	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FGL65_RS12035	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FGL65_RS12035	COG1648	precorrin-2 dehydrogenase activity
FGL65_RS12060	COG0019	diaminopimelate decarboxylase activity
FGL65_RS12075	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FGL65_RS12090	COG3620	sequence-specific DNA binding
FGL65_RS12090	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FGL65_RS12090	COG0617	tRNA 3'-terminal CCA addition
FGL65_RS12095	COG4974	Belongs to the 'phage' integrase family
FGL65_RS12100	COG0436	Aminotransferase
FGL65_RS12105	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FGL65_RS12140	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FGL65_RS12145	COG0149	triose-phosphate isomerase activity
FGL65_RS12150	COG0126	phosphoglycerate kinase activity
FGL65_RS12155	COG0456	acetyltransferase
FGL65_RS12165	COG0483	inositol monophosphate 1-phosphatase activity
FGL65_RS12180	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FGL65_RS12195	COG1187	pseudouridine synthase activity
FGL65_RS12200	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FGL65_RS12205	COG1674	ftsk spoiiie
FGL65_RS12205	COG1178	ABC-type Fe3 transport system permease component
FGL65_RS12210	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FGL65_RS12215	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FGL65_RS12220	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FGL65_RS12240	COG1968	undecaprenyl-diphosphatase activity
FGL65_RS12265	COG0366	Alpha amylase catalytic
FGL65_RS12305	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FGL65_RS12325	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FGL65_RS12325	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FGL65_RS12335	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FGL65_RS12340	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FGL65_RS12340	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FGL65_RS12345	COG0617	tRNA 3'-terminal CCA addition
FGL65_RS12375	COG0719	Fe-S assembly protein
FGL65_RS12380	COG0396	ATPase activity
FGL65_RS12385	COG2840	Smr protein MutS2
FGL65_RS12390	COG0835	chemotaxis
FGL65_RS12410	COG1785	Belongs to the alkaline phosphatase family
FGL65_RS12445	COG1067	ATP-dependent peptidase activity
FGL65_RS12485	COG1045	serine acetyltransferase
FGL65_RS12490	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FGL65_RS12495	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FGL65_RS12500	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FGL65_RS12530	COG2239	Acts as a magnesium transporter
FGL65_RS12535	COG0157	Belongs to the NadC ModD family
FGL65_RS12540	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FGL65_RS12550	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FGL65_RS12570	COG0569	domain protein
FGL65_RS12575	COG3005	denitrification pathway
FGL65_RS12590	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FGL65_RS12610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FGL65_RS12615	COG0268	Binds directly to 16S ribosomal RNA
FGL65_RS12620	COG0751	glycine-tRNA ligase activity
FGL65_RS12625	COG0752	glycyl-tRNA synthetase alpha subunit
FGL65_RS12630	COG1381	Involved in DNA repair and RecF pathway recombination
FGL65_RS12635	COG1426	Protein conserved in bacteria
FGL65_RS12650	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FGL65_RS12655	COG0835	chemotaxis
FGL65_RS12675	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FGL65_RS12680	COG0736	holo-[acyl-carrier-protein] synthase activity
FGL65_RS12685	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FGL65_RS12685	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FGL65_RS12690	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FGL65_RS12695	COG0802	atpase or kinase
FGL65_RS12700	COG0527	aspartate kinase activity
FGL65_RS12705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FGL65_RS12720	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FGL65_RS12725	COG3481	metal-dependent phosphohydrolase, HD sub domain
FGL65_RS12730	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FGL65_RS12735	COG0765	amino acid transport
FGL65_RS12740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGL65_RS12745	COG0765	amino acid transport
FGL65_RS12765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FGL65_RS12770	COG2873	o-acetylhomoserine
FGL65_RS12775	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FGL65_RS12780	COG0444	Belongs to the ABC transporter superfamily
FGL65_RS12785	COG4608	Belongs to the ABC transporter superfamily
FGL65_RS12800	COG1122	ATPase activity
FGL65_RS12825	COG0210	DNA helicase
FGL65_RS12830	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FGL65_RS12845	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
FGL65_RS12850	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FGL65_RS12855	COG0440	acetolactate synthase activity
FGL65_RS12860	COG0028	Belongs to the TPP enzyme family
FGL65_RS12870	COG1872	DUF167
FGL65_RS12900	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FGL65_RS12905	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FGL65_RS12925	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FGL65_RS12935	COG0742	ribosomal rna small subunit methyltransferase
FGL65_RS12940	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FGL65_RS12945	COG1611	Belongs to the LOG family
FGL65_RS12965	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FGL65_RS12980	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FGL65_RS13000	COG0534	Mate efflux family protein
FGL65_RS13005	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FGL65_RS13010	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FGL65_RS13035	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FGL65_RS13040	COG0542	response to heat
FGL65_RS13045	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FGL65_RS13055	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FGL65_RS13060	COG1993	acr, cog1993
FGL65_RS13065	COG2201	protein-glutamate methylesterase activity
FGL65_RS13070	COG2198	Histidine kinase
FGL65_RS13070	COG0643	Histidine kinase
FGL65_RS13075	COG0840	transmembrane signaling receptor activity
FGL65_RS13085	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FGL65_RS13095	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FGL65_RS13100	COG0492	ferredoxin-NADP+ reductase activity
FGL65_RS13105	COG3118	belongs to the thioredoxin family
FGL65_RS13110	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FGL65_RS13115	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FGL65_RS13140	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FGL65_RS13145	COG0489	protein tyrosine kinase activity
FGL65_RS13155	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FGL65_RS13180	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FGL65_RS13190	COG0740	serine-type endopeptidase activity
FGL65_RS13195	COG0544	peptidyl-prolyl cis-trans isomerase activity
FGL65_RS13205	COG0351	phosphomethylpyrimidine kinase
FGL65_RS13230	COG2204	response regulator
FGL65_RS13255	COG2204	response regulator
FGL65_RS13265	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FGL65_RS13275	COG2169	Transcriptional regulator
FGL65_RS13275	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FGL65_RS13350	COG3708	Transcriptional regulator
FGL65_RS13350	COG2207	Transcriptional regulator
FGL65_RS13360	COG0017	Asparaginyl-tRNA synthetase
FGL65_RS13365	COG0552	protein localization to endoplasmic reticulum
FGL65_RS13370	COG0539	negative regulation of cytoplasmic translation
FGL65_RS13380	COG2610	gluconate transmembrane transporter activity
FGL65_RS13395	COG0564	pseudouridine synthase activity
FGL65_RS13410	COG1074	ATP-dependent DNA helicase activity
FGL65_RS13425	COG0579	oxidoreductase
FGL65_RS13435	COG0697	spore germination
FGL65_RS13445	COG4974	Belongs to the 'phage' integrase family
FGL65_RS13450	COG0745	RESPONSE REGULATOR receiver
FGL65_RS13465	COG2119	membrane
FGL65_RS13470	COG0758	DNA mediated transformation
FGL65_RS13485	COG0784	Response regulator, receiver
FGL65_RS13485	COG2198	Histidine kinase
FGL65_RS13485	COG0643	Histidine kinase
FGL65_RS13485	COG0784	Response regulator, receiver
FGL65_RS13485	COG2198	Histidine kinase
FGL65_RS13485	COG0643	Histidine kinase
FGL65_RS13490	COG0745	RESPONSE REGULATOR receiver
FGL65_RS13505	COG2201	protein-glutamate methylesterase activity
FGL65_RS13515	COG3158	transport of potassium into the cell
FGL65_RS13525	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FGL65_RS13530	COG1760	l-serine dehydratase
FGL65_RS13540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGL65_RS13545	COG0765	amino acid transport
FGL65_RS13570	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FGL65_RS13580	COG0784	Response regulator, receiver
FGL65_RS13580	COG2205	protein histidine kinase activity
FGL65_RS13590	COG4771	TonB-dependent receptor
FGL65_RS13610	COG0629	single-stranded DNA binding
FGL65_RS13625	COG0825	malonyl-CoA metabolic process
FGL65_RS13630	COG0439	Biotin carboxylase
FGL65_RS13645	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FGL65_RS13650	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FGL65_RS13670	COG1013	pyruvate-flavodoxin oxidoreductase activity
FGL65_RS13675	COG0674	pyruvate-flavodoxin oxidoreductase activity
FGL65_RS13675	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FGL65_RS13680	COG1144	Oxidoreductase
FGL65_RS13690	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FGL65_RS13695	COG0765	amino acid transport
FGL65_RS13700	COG0765	amino acid transport
FGL65_RS13710	COG1126	abc transporter atp-binding protein
FGL65_RS13730	COG1053	succinate dehydrogenase
FGL65_RS13735	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FGL65_RS13750	COG0281	malic enzyme
FGL65_RS13750	COG0280	phosphate acetyltransferase
FGL65_RS13755	COG0471	metal ion transport
FGL65_RS13760	COG0280	phosphate acetyltransferase
FGL65_RS13760	COG0857	belongs to the CobB CobQ family
FGL65_RS13780	COG5557	Pfam Polysulphide reductase, NrfD
FGL65_RS13785	COG0437	4 iron, 4 sulfur cluster binding
FGL65_RS13790	COG0243	molybdopterin cofactor binding
FGL65_RS13805	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FGL65_RS13815	COG3956	TIGRFAM MazG family protein
FGL65_RS13830	COG2048	Heterodisulfide reductase, subunit B
FGL65_RS13870	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FGL65_RS13880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGL65_RS13885	COG1120	ATPase activity
FGL65_RS13890	COG0500	methyltransferase
FGL65_RS13900	COG1160	GTP binding
FGL65_RS13905	COG1331	Highly conserved protein containing a thioredoxin domain
FGL65_RS13910	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FGL65_RS13915	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FGL65_RS13925	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FGL65_RS13935	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FGL65_RS13950	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FGL65_RS13955	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FGL65_RS13960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FGL65_RS13965	COG4786	Flagellar basal body rod
FGL65_RS13965	COG1256	bacterial-type flagellum assembly
FGL65_RS13980	COG1706	bacterial-type flagellum-dependent cell motility
FGL65_RS14000	COG4786	Flagellar basal body rod
FGL65_RS14010	COG0779	Required for maturation of 30S ribosomal subunits
FGL65_RS14015	COG0195	Participates in both transcription termination and antitermination
FGL65_RS14025	COG3266	domain, Protein
FGL65_RS14025	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FGL65_RS14035	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FGL65_RS14040	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FGL65_RS14045	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FGL65_RS14050	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FGL65_RS14055	COG1185	polyribonucleotide nucleotidyltransferase activity
FGL65_RS14075	COG1355	regulation of microtubule-based process
FGL65_RS14105	COG1469	GTP cyclohydrolase I activity
FGL65_RS14110	COG0864	Transcriptional regulator
FGL65_RS14120	COG0509	glycine decarboxylation via glycine cleavage system
FGL65_RS14125	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FGL65_RS14130	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FGL65_RS14135	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FGL65_RS14150	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FGL65_RS14160	COG2048	Heterodisulfide reductase, subunit B
FGL65_RS14165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FGL65_RS14210	COG3681	Belongs to the UPF0597 family
FGL65_RS14220	COG0038	chloride channel
FGL65_RS14230	COG1028	Short-chain dehydrogenase reductase Sdr
FGL65_RS14235	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FGL65_RS14250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGL65_RS14270	COG0602	queuosine metabolic process
FGL65_RS14305	COG0463	Glycosyl transferase, family 2
FGL65_RS14315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGL65_RS14320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FGL65_RS14340	COG0673	inositol 2-dehydrogenase activity
FGL65_RS14345	COG0531	amino acid
FGL65_RS14350	COG0076	glutamate decarboxylase activity
FGL65_RS14355	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FGL65_RS14370	COG0659	secondary active sulfate transmembrane transporter activity
FGL65_RS14380	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FGL65_RS14390	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FGL65_RS14395	COG0052	Belongs to the universal ribosomal protein uS2 family
FGL65_RS14410	COG0233	cytoplasmic translational termination
FGL65_RS14420	COG4589	Belongs to the CDS family
FGL65_RS14425	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FGL65_RS14430	COG0750	zinc metalloprotease
FGL65_RS14440	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FGL65_RS14445	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FGL65_RS14475	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FGL65_RS14475	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FGL65_RS14485	COG0438	transferase activity, transferring glycosyl groups
FGL65_RS14510	COG0535	radical SAM domain protein
FGL65_RS14515	COG0113	porphobilinogen synthase activity
FGL65_RS14520	COG0535	radical SAM domain protein
FGL65_RS14525	COG1522	sequence-specific DNA binding
FGL65_RS14535	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FGL65_RS14540	COG0488	(ABC) transporter
FGL65_RS14555	COG1127	ABC transporter
FGL65_RS14570	COG1012	belongs to the aldehyde dehydrogenase family
FGL65_RS14575	COG2188	Transcriptional regulator
FGL65_RS14580	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FGL65_RS14585	COG1228	amidohydrolase
FGL65_RS14595	COG2986	histidine ammonia-lyase
FGL65_RS14625	COG2204	response regulator
FGL65_RS14645	COG1181	Belongs to the D-alanine--D-alanine ligase family
FGL65_RS14650	COG1181	Belongs to the D-alanine--D-alanine ligase family
FGL65_RS14655	COG1509	lysine 2,3-aminomutase activity
FGL65_RS14685	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FGL65_RS14690	COG2342	PFAM TM1410 hypothetical-related protein
FGL65_RS14695	COG1335	isochorismatase
FGL65_RS14730	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FGL65_RS14740	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FGL65_RS14745	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FGL65_RS14760	COG0583	DNA-binding transcription factor activity
FGL65_RS14765	COG0203	ribosomal protein L17
FGL65_RS14770	COG0202	RNA polymerase activity
FGL65_RS14775	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FGL65_RS14780	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FGL65_RS14785	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FGL65_RS14810	COG0200	Binds to the 23S rRNA
FGL65_RS14815	COG1841	ribosomal large subunit assembly
FGL65_RS14820	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FGL65_RS14830	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FGL65_RS14835	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FGL65_RS14840	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FGL65_RS14845	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FGL65_RS14855	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FGL65_RS14860	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FGL65_RS14865	COG0255	Belongs to the universal ribosomal protein uL29 family
FGL65_RS14870	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FGL65_RS14875	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FGL65_RS14880	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FGL65_RS14885	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FGL65_RS14890	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FGL65_RS14895	COG0089	rRNA binding
FGL65_RS14900	COG0088	Forms part of the polypeptide exit tunnel
FGL65_RS14905	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FGL65_RS14910	COG0051	transcription antitermination factor activity, RNA binding
FGL65_RS14915	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FGL65_RS14920	COG0049	tRNA binding
FGL65_RS14930	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FGL65_RS14935	COG0085	RNA polymerase activity
FGL65_RS14940	COG0222	ribosome binding
FGL65_RS14945	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FGL65_RS14955	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FGL65_RS14960	COG0250	Participates in transcription elongation, termination and antitermination
FGL65_RS14980	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FGL65_RS15010	COG0835	chemotaxis
FGL65_RS15010	COG0784	Response regulator, receiver
FGL65_RS15015	COG2267	carboxylic ester hydrolase activity
FGL65_RS15020	COG0309	Hydrogenase expression formation protein (HypE)
FGL65_RS15030	COG2920	part of a sulfur-relay system
FGL65_RS15050	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FGL65_RS15055	COG0505	Belongs to the CarA family
FGL65_RS15065	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FGL65_RS15070	COG0384	phenazine biosynthesis protein PhzF
FGL65_RS15080	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FGL65_RS15085	COG0494	nUDIX hydrolase
FGL65_RS15090	COG5002	protein histidine kinase activity
FGL65_RS15095	COG0009	L-threonylcarbamoyladenylate synthase
FGL65_RS15100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FGL65_RS15105	COG2204	response regulator
FGL65_RS15115	COG0643	Histidine kinase
FGL65_RS15115	COG2198	Histidine kinase
FGL65_RS15120	COG4822	anaerobic cobalamin biosynthetic process
FGL65_RS15125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGL65_RS15130	COG1120	ATPase activity
FGL65_RS15145	COG4822	anaerobic cobalamin biosynthetic process
FGL65_RS15165	COG0321	lipoyl(octanoyl) transferase activity
FGL65_RS15170	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FGL65_RS15175	COG0784	Response regulator, receiver
FGL65_RS15175	COG2205	protein histidine kinase activity
FGL65_RS15180	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FGL65_RS15185	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FGL65_RS15185	COG1328	CTP reductase activity
FGL65_RS15195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FGL65_RS15225	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FGL65_RS15260	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FGL65_RS15265	COG1121	(ABC) transporter
FGL65_RS15290	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FGL65_RS15295	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FGL65_RS15310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FGL65_RS15325	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FGL65_RS15330	COG0594	ribonuclease P activity
FGL65_RS15335	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FGL65_RS15340	COG0706	membrane insertase activity
FGL65_RS15345	COG1847	R3H domain protein
FGL65_RS15365	COG0463	Glycosyl transferase, family 2
FGL65_RS15390	COG0693	protein deglycase activity
FGL65_RS15400	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FGL65_RS15405	COG0538	isocitrate dehydrogenase activity
FGL65_RS15410	COG1280	lysine exporter protein (LysE YggA)
FGL65_RS15440	COG0840	transmembrane signaling receptor activity
FGL65_RS15450	COG1309	transcriptional regulator
FGL65_RS15465	COG2198	Histidine kinase
FGL65_RS15465	COG0784	Response regulator, receiver
FGL65_RS15465	COG2205	protein histidine kinase activity
FGL65_RS15475	COG3437	response regulator, receiver
FGL65_RS15520	COG0557	exoribonuclease II activity
FGL65_RS15525	COG1663	tetraacyldisaccharide 4'-kinase activity
FGL65_RS15530	COG0670	Belongs to the BI1 family
FGL65_RS15555	COG0840	transmembrane signaling receptor activity
FGL65_RS15560	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FGL65_RS15580	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FGL65_RS15585	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FGL65_RS15605	COG1979	alcohol dehydrogenase
FGL65_RS15610	COG2207	Transcriptional regulator
FGL65_RS15615	COG0640	Transcriptional regulator
FGL65_RS15620	COG0655	NAD(P)H dehydrogenase (quinone) activity
FGL65_RS15630	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FGL65_RS15670	COG2814	Major facilitator Superfamily
FGL65_RS15675	COG1959	2 iron, 2 sulfur cluster binding
FGL65_RS15685	COG0310	cobalt ion transport
FGL65_RS15710	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FGL65_RS15740	COG0469	pyruvate kinase activity
FGL65_RS15745	COG2001	Belongs to the MraZ family
FGL65_RS15750	COG0275	rRNA processing
FGL65_RS15765	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FGL65_RS15770	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FGL65_RS15775	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FGL65_RS15780	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FGL65_RS15785	COG0772	Belongs to the SEDS family
FGL65_RS15790	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FGL65_RS15795	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FGL65_RS15800	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FGL65_RS15805	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FGL65_RS15820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FGL65_RS15845	COG4191	Histidine kinase
FGL65_RS15865	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FGL65_RS15875	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FGL65_RS15885	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FGL65_RS15895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FGL65_RS15905	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGL65_RS15910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FGL65_RS15920	COG2131	deaminase
FGL65_RS15935	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FGL65_RS15940	COG1309	transcriptional regulator
FGL65_RS15960	COG0519	Catalyzes the synthesis of GMP from XMP
FGL65_RS15970	COG5557	Pfam Polysulphide reductase, NrfD
FGL65_RS15975	COG0437	4 iron, 4 sulfur cluster binding
FGL65_RS15975	COG3064	Membrane
FGL65_RS15980	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FGL65_RS15980	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FGL65_RS15985	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FGL65_RS15990	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FGL65_RS15995	COG0495	leucyl-tRNA aminoacylation
FGL65_RS16010	COG2003	Belongs to the UPF0758 family
FGL65_RS16015	COG1254	Belongs to the acylphosphatase family
FGL65_RS16020	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FGL65_RS16045	COG0181	hydroxymethylbilane synthase activity
FGL65_RS16065	COG3012	SEC-C Motif Domain Protein
FGL65_RS16095	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FGL65_RS16105	COG1722	exodeoxyribonuclease VII activity
FGL65_RS16120	COG0739	heme binding
FGL65_RS16130	COG1570	exodeoxyribonuclease VII activity
FGL65_RS16135	COG1280	lysine exporter protein (LysE YggA)
FGL65_RS16140	COG0442	prolyl-tRNA aminoacylation
FGL65_RS16145	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FGL65_RS16150	COG1592	Rubrerythrin
FGL65_RS16160	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FGL65_RS16165	COG0702	epimerase
FGL65_RS16175	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FGL65_RS16185	COG2270	Major facilitator Superfamily
FGL65_RS16190	COG2078	PFAM AMMECR1 domain protein
FGL65_RS16225	COG0432	Pfam Uncharacterised protein family UPF0047
FGL65_RS16245	COG1215	transferase activity, transferring glycosyl groups
FGL65_RS16260	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FGL65_RS16275	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FGL65_RS16275	COG1587	Uroporphyrinogen-III synthase
FGL65_RS16280	COG0525	valine-tRNA ligase activity
FGL65_RS16295	COG1191	sigma factor activity
FGL65_RS16310	COG1749	Flagellar hook protein flgE
FGL65_RS16315	COG1256	bacterial-type flagellum assembly
FGL65_RS16325	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FGL65_RS16330	COG1595	DNA-templated transcription, initiation
FGL65_RS16355	COG0101	tRNA pseudouridine synthase activity
FGL65_RS16375	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FGL65_RS16390	COG1797	cobyrinic acid a,c-diamide synthase activity
FGL65_RS16430	COG3261	NADH dehydrogenase
FGL65_RS16430	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FGL65_RS16440	COG3260	NADH ubiquinone oxidoreductase 20
FGL65_RS16445	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FGL65_RS16450	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FGL65_RS16450	COG2111	Na H antiporter
FGL65_RS16455	COG0175	sulfate reduction
FGL65_RS16485	COG3422	double-strand break repair
FGL65_RS16515	COG1842	Phage shock protein A
FGL65_RS16520	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FGL65_RS16540	COG2264	protein methyltransferase activity
FGL65_RS16580	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FGL65_RS16585	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FGL65_RS16605	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FGL65_RS16605	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FGL65_RS16620	COG3842	ATPase activity
FGL65_RS16630	COG1177	transmembrane transport
FGL65_RS16660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGL65_RS16710	COG0574	Belongs to the PEP-utilizing enzyme family
FGL65_RS16710	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FGL65_RS16720	COG1254	Belongs to the acylphosphatase family
FGL65_RS16725	COG5002	protein histidine kinase activity
FGL65_RS16730	COG2204	response regulator
FGL65_RS16740	COG0835	chemotaxis
FGL65_RS16740	COG0784	Response regulator, receiver
FGL65_RS16750	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FGL65_RS16755	COG0745	RESPONSE REGULATOR receiver
FGL65_RS16760	COG5002	protein histidine kinase activity
FGL65_RS16770	COG2205	protein histidine kinase activity
FGL65_RS16770	COG2202	Pas domain
FGL65_RS16775	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FGL65_RS16795	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FGL65_RS16820	COG0110	maltose O-acetyltransferase activity
FGL65_RS16830	COG1979	alcohol dehydrogenase
FGL65_RS16845	COG0583	DNA-binding transcription factor activity
FGL65_RS16870	COG4191	Histidine kinase
FGL65_RS16870	COG0784	Response regulator, receiver
FGL65_RS16880	COG2207	Transcriptional regulator
FGL65_RS16880	COG4753	response regulator
FGL65_RS16900	COG1937	Protein conserved in bacteria
FGL65_RS16910	COG0028	Belongs to the TPP enzyme family
FGL65_RS16915	COG0440	acetolactate synthase activity
FGL65_RS16920	COG0733	neurotransmitter:sodium symporter activity
FGL65_RS16930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGL65_RS16940	COG4191	Histidine kinase
FGL65_RS16940	COG2205	protein histidine kinase activity
FGL65_RS16940	COG0745	RESPONSE REGULATOR receiver
FGL65_RS16955	COG0778	Nitroreductase
FGL65_RS16995	COG0688	phosphatidylethanolamine metabolic process
FGL65_RS17035	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FGL65_RS17040	COG4895	conserved protein (DUF2196)
FGL65_RS17045	COG1280	lysine exporter protein (LysE YggA)
FGL65_RS17055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGL65_RS17075	COG0840	transmembrane signaling receptor activity
FGL65_RS17090	COG2204	response regulator
FGL65_RS17105	COG5002	protein histidine kinase activity
FGL65_RS17120	COG1309	transcriptional regulator
FGL65_RS17140	COG1121	(ABC) transporter
FGL65_RS17170	COG1918	ferrous iron import across plasma membrane
FGL65_RS17170	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FGL65_RS17195	COG0735	belongs to the Fur family
FGL65_RS17215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FGL65_RS17240	COG0737	Belongs to the 5'-nucleotidase family
FGL65_RS17255	COG0513	Belongs to the DEAD box helicase family
FGL65_RS17260	COG1177	transmembrane transport
FGL65_RS17265	COG1176	ABC-type spermidine putrescine transport system, permease component I
FGL65_RS17270	COG3842	ATPase activity
FGL65_RS17275	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FGL65_RS17280	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FGL65_RS17295	COG2205	protein histidine kinase activity
FGL65_RS17295	COG2198	Histidine kinase
FGL65_RS17295	COG0784	Response regulator, receiver
FGL65_RS17300	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FGL65_RS17310	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FGL65_RS17330	COG0840	transmembrane signaling receptor activity
FGL65_RS17330	COG3290	protein histidine kinase activity
FGL65_RS17340	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FGL65_RS17355	COG2204	response regulator
FGL65_RS17360	COG0574	Belongs to the PEP-utilizing enzyme family
FGL65_RS17360	COG3848	Pyruvate phosphate dikinase
FGL65_RS17375	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FGL65_RS17380	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FGL65_RS17390	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FGL65_RS17405	COG1012	belongs to the aldehyde dehydrogenase family
FGL65_RS17410	COG0583	DNA-binding transcription factor activity
FGL65_RS17415	COG0583	DNA-binding transcription factor activity
FGL65_RS17420	COG0583	DNA-binding transcription factor activity
FGL65_RS17430	COG0583	DNA-binding transcription factor activity
FGL65_RS17440	COG0583	DNA-binding transcription factor activity
FGL65_RS17460	COG0840	transmembrane signaling receptor activity
FGL65_RS17505	COG0534	Mate efflux family protein
FGL65_RS17525	COG5001	Diguanylate cyclase
FGL65_RS17535	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FGL65_RS17540	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FGL65_RS17555	COG2200	EAL domain
FGL65_RS17560	COG0347	Belongs to the P(II) protein family
FGL65_RS17565	COG0004	ammonium transporteR
FGL65_RS17570	COG1830	Aldolase
FGL65_RS17575	COG1465	3-dehydroquinate synthase
FGL65_RS17580	COG0077	Prephenate dehydratase
FGL65_RS17580	COG1605	Chorismate mutase
FGL65_RS17585	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FGL65_RS17595	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FGL65_RS17605	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FGL65_RS17610	COG0134	indole-3-glycerol-phosphate synthase activity
FGL65_RS17615	COG0135	phosphoribosylanthranilate isomerase activity
FGL65_RS17625	COG0159	tryptophan synthase activity
FGL65_RS17665	COG0583	DNA-binding transcription factor activity
FGL65_RS17670	COG0243	molybdopterin cofactor binding
FGL65_RS17675	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGL65_RS17680	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGL65_RS17685	COG0649	NAD binding
FGL65_RS17690	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FGL65_RS17700	COG0839	Belongs to the complex I subunit 6 family
FGL65_RS17705	COG0713	ATP synthesis coupled electron transport
FGL65_RS17710	COG0651	ATP synthesis coupled electron transport
FGL65_RS17720	COG0651	ATP synthesis coupled electron transport
FGL65_RS17730	COG1007	ATP synthesis coupled electron transport
FGL65_RS17750	COG0589	response to stress
FGL65_RS17775	COG2203	Gaf domain
FGL65_RS17775	COG5001	Diguanylate cyclase
FGL65_RS17775	COG4251	negative regulation of phosphorylation
FGL65_RS17775	COG3706	GGDEF domain
FGL65_RS17785	COG5002	protein histidine kinase activity
FGL65_RS17805	COG0024	Methionine aminopeptidase
FGL65_RS17815	COG2824	Alkylphosphonate utilization operon protein PhnA
FGL65_RS17830	COG0531	amino acid
FGL65_RS17845	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FGL65_RS17865	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FGL65_RS17895	COG3267	Type II secretory pathway component ExeA
FGL65_RS17895	COG3409	Peptidoglycan-binding domain 1 protein
FGL65_RS17915	COG4966	pilus assembly protein PilW
FGL65_RS17990	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FGL65_RS17995	COG1122	ATPase activity
FGL65_RS18000	COG1122	ATPase activity
FGL65_RS18015	COG0437	4 iron, 4 sulfur cluster binding
FGL65_RS18035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FGL65_RS18040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain