locus-tag	class	description
G7047_RS00095	COG0582	viral genome integration into host DNA
G7047_RS00105	COG3276	selenocysteine insertion sequence binding
G7047_RS00110	COG1921	L-seryl-tRNASec selenium transferase activity
G7047_RS00120	COG2864	formate dehydrogenase
G7047_RS00125	COG0437	4 iron, 4 sulfur cluster binding
G7047_RS00135	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G7047_RS00140	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
G7047_RS00155	COG0737	Belongs to the 5'-nucleotidase family
G7047_RS00160	COG3209	COG3209 Rhs family protein
G7047_RS00165	COG1193	negative regulation of DNA recombination
G7047_RS00170	COG2003	Belongs to the UPF0758 family
G7047_RS00180	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G7047_RS00185	COG1253	flavin adenine dinucleotide binding
G7047_RS00190	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G7047_RS00205	COG0745	RESPONSE REGULATOR receiver
G7047_RS00210	COG5002	protein histidine kinase activity
G7047_RS00240	COG0405	Gamma-glutamyltransferase
G7047_RS00255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G7047_RS00265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7047_RS00270	COG1301	dicarboxylic acid transport
G7047_RS00280	COG0583	DNA-binding transcription factor activity
G7047_RS00285	COG2080	2 iron, 2 sulfur cluster binding
G7047_RS00290	COG2010	Cytochrome c
G7047_RS00290	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G7047_RS00295	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G7047_RS00295	COG2010	Cytochrome c
G7047_RS00325	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G7047_RS00330	COG2199	diguanylate cyclase activity
G7047_RS00335	COG0252	asparaginase activity
G7047_RS00340	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G7047_RS00345	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G7047_RS00360	COG4191	Histidine kinase
G7047_RS00370	COG1846	Transcriptional regulator
G7047_RS00380	COG3119	arylsulfatase activity
G7047_RS00385	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G7047_RS00390	COG1216	Glycosyl transferase, family 2
G7047_RS00390	COG0438	transferase activity, transferring glycosyl groups
G7047_RS00400	COG2205	protein histidine kinase activity
G7047_RS00405	COG0745	RESPONSE REGULATOR receiver
G7047_RS00445	COG4774	siderophore transport
G7047_RS00545	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G7047_RS00550	COG0672	)-iron permease
G7047_RS00565	COG0789	Transcriptional regulator
G7047_RS00640	COG0582	viral genome integration into host DNA
G7047_RS00695	COG0402	S-adenosylhomocysteine deaminase activity
G7047_RS00700	COG0523	cobalamin synthesis protein
G7047_RS00715	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G7047_RS00720	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS00735	COG1414	Transcriptional regulator
G7047_RS00750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G7047_RS00755	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
G7047_RS00760	COG4521	taurine ABC transporter
G7047_RS00775	COG1113	amino acid transport
G7047_RS00780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G7047_RS00790	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G7047_RS00800	COG5002	protein histidine kinase activity
G7047_RS00810	COG0745	RESPONSE REGULATOR receiver
G7047_RS00815	COG0180	Tryptophanyl-tRNA synthetase
G7047_RS00820	COG1994	Peptidase M50
G7047_RS00825	COG0009	L-threonylcarbamoyladenylate synthase
G7047_RS00830	COG0613	PHP domain protein
G7047_RS00845	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G7047_RS00855	COG4591	ABC-type transport system involved in lipoprotein release permease component
G7047_RS00860	COG1136	(ABC) transporter
G7047_RS00865	COG2304	oxidoreductase activity
G7047_RS00875	COG0714	Associated with various cellular activities
G7047_RS00880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G7047_RS00885	COG0084	hydrolase, TatD family'
G7047_RS00895	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
G7047_RS00900	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G7047_RS00915	COG0697	spore germination
G7047_RS00920	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS00930	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G7047_RS00950	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS00970	COG0412	Dienelactone hydrolase
G7047_RS00985	COG3275	phosphorelay sensor kinase activity
G7047_RS00990	COG0165	Argininosuccinate lyase
G7047_RS01010	COG1802	Transcriptional regulator
G7047_RS01030	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G7047_RS01040	COG1304	FMN binding
G7047_RS01055	COG1309	transcriptional regulator
G7047_RS01065	COG1309	transcriptional regulator
G7047_RS01080	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G7047_RS01085	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G7047_RS01085	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G7047_RS01095	COG3022	response to hydroperoxide
G7047_RS01100	COG1530	ribonuclease E activity
G7047_RS01120	COG0616	signal peptide processing
G7047_RS01120	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G7047_RS01125	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
G7047_RS01130	COG0424	maF-like protein
G7047_RS01135	COG1399	metal-binding, possibly nucleic acid-binding protein
G7047_RS01140	COG0333	Belongs to the bacterial ribosomal protein bL32 family
G7047_RS01145	COG0416	fatty acid biosynthetic process
G7047_RS01150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G7047_RS01160	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS01165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G7047_RS01170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G7047_RS01195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G7047_RS01200	COG0481	GTPase activity
G7047_RS01205	COG0681	Belongs to the peptidase S26 family
G7047_RS01215	COG0571	ribonuclease III activity
G7047_RS01220	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G7047_RS01225	COG1381	Involved in DNA repair and RecF pathway recombination
G7047_RS01230	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
G7047_RS01235	COG0736	holo-[acyl-carrier-protein] synthase activity
G7047_RS01240	COG1472	Belongs to the glycosyl hydrolase 3 family
G7047_RS01245	COG0583	DNA-binding transcription factor activity
G7047_RS01250	COG4178	(ABC) transporter
G7047_RS01265	COG3706	GGDEF domain
G7047_RS01270	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G7047_RS01285	COG1215	transferase activity, transferring glycosyl groups
G7047_RS01295	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G7047_RS01300	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G7047_RS01315	COG0762	integral membrane protein
G7047_RS01325	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G7047_RS01330	COG0159	tryptophan synthase activity
G7047_RS01335	COG0133	tryptophan synthase activity
G7047_RS01340	COG0135	phosphoribosylanthranilate isomerase activity
G7047_RS01345	COG0101	tRNA pseudouridine synthase activity
G7047_RS01355	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G7047_RS01360	COG3422	double-strand break repair
G7047_RS01365	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G7047_RS01375	COG0473	3-isopropylmalate dehydrogenase activity
G7047_RS01380	COG0066	3-isopropylmalate dehydratase activity
G7047_RS01390	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G7047_RS01400	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
G7047_RS01405	COG0163	prenyltransferase activity
G7047_RS01415	COG3154	lipid carrier protein
G7047_RS01420	COG0826	peptidase U32
G7047_RS01425	COG0826	peptidase U32
G7047_RS01430	COG1297	OPT oligopeptide transporter protein
G7047_RS01435	COG0484	heat shock protein binding
G7047_RS01440	COG0443	Heat shock 70 kDa protein
G7047_RS01445	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G7047_RS01450	COG0360	Binds together with S18 to 16S ribosomal RNA
G7047_RS01455	COG2965	DNA replication, synthesis of RNA primer
G7047_RS01460	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G7047_RS01465	COG0359	binds to the 23S rRNA
G7047_RS01470	COG0305	Participates in initiation and elongation during chromosome replication
G7047_RS01485	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G7047_RS01490	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G7047_RS01500	COG0436	Aminotransferase
G7047_RS01515	COG1763	Mo-molybdopterin cofactor biosynthetic process
G7047_RS01520	COG0303	'Molybdopterin
G7047_RS01525	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
G7047_RS01565	COG0314	molybdopterin synthase activity
G7047_RS01575	COG0542	response to heat
G7047_RS01600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G7047_RS01735	COG1802	Transcriptional regulator
G7047_RS01750	COG2353	YceI-like domain
G7047_RS01760	COG1289	transmembrane transporter activity
G7047_RS01770	COG1960	acyl-CoA dehydrogenase activity
G7047_RS01785	COG0280	phosphate acetyltransferase
G7047_RS01785	COG0281	malic enzyme
G7047_RS01790	COG2233	PERMEase
G7047_RS01800	COG2814	Major facilitator Superfamily
G7047_RS01805	COG0583	DNA-binding transcription factor activity
G7047_RS01825	COG2159	amidohydrolase
G7047_RS01835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G7047_RS01850	COG2186	Transcriptional regulator
G7047_RS01880	COG0402	S-adenosylhomocysteine deaminase activity
G7047_RS01885	COG0717	Belongs to the dCTP deaminase family
G7047_RS01890	COG2321	neutral zinc metallopeptidase
G7047_RS01895	COG0513	Belongs to the DEAD box helicase family
G7047_RS01905	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
G7047_RS01920	COG3901	Regulator of nitric oxide reductase transcription
G7047_RS01920	COG0348	domain, Protein
G7047_RS01925	COG4263	nitrous-oxide reductase activity
G7047_RS01935	COG3245	cytochrome
G7047_RS01940	COG1477	protein flavinylation
G7047_RS01945	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G7047_RS01955	COG2916	Histone family protein nucleoid-structuring protein H-NS
G7047_RS01960	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G7047_RS01965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G7047_RS01975	COG1968	undecaprenyl-diphosphatase activity
G7047_RS01980	COG2267	carboxylic ester hydrolase activity
G7047_RS01995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G7047_RS02010	COG0165	Argininosuccinate lyase
G7047_RS02030	COG3275	phosphorelay sensor kinase activity
G7047_RS02040	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
G7047_RS02050	COG0583	DNA-binding transcription factor activity
G7047_RS02075	COG0446	pyridine nucleotide-disulphide oxidoreductase
G7047_RS02080	COG3540	Alkaline phosphatase
G7047_RS02085	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G7047_RS02090	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G7047_RS02100	COG0564	pseudouridine synthase activity
G7047_RS02105	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G7047_RS02110	COG1187	pseudouridine synthase activity
G7047_RS02115	COG0105	UTP biosynthetic process
G7047_RS02120	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G7047_RS02135	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G7047_RS02140	COG0124	histidyl-tRNA synthetase
G7047_RS02150	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G7047_RS02155	COG1160	GTP binding
G7047_RS02160	COG1923	regulation of RNA biosynthetic process
G7047_RS02165	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G7047_RS02170	COG0330	HflC and HflK could
G7047_RS02175	COG0330	HflC and HflK could
G7047_RS02180	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
G7047_RS02185	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
G7047_RS02190	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G7047_RS02220	COG1187	pseudouridine synthase activity
G7047_RS02245	COG1546	Belongs to the CinA family
G7047_RS02245	COG1058	Belongs to the CinA family
G7047_RS02250	COG0174	glutamine synthetase
G7047_RS02260	COG3852	Histidine kinase
G7047_RS02265	COG2204	response regulator
G7047_RS02275	COG1595	DNA-templated transcription, initiation
G7047_RS02285	COG0708	Exodeoxyribonuclease III
G7047_RS02445	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G7047_RS02510	COG1595	DNA-templated transcription, initiation
G7047_RS02535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G7047_RS02560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G7047_RS02570	COG4774	siderophore transport
G7047_RS02590	COG2366	antibiotic biosynthetic process
G7047_RS02630	COG0735	belongs to the Fur family
G7047_RS02650	COG4771	TonB-dependent receptor
G7047_RS02705	COG4771	TonB-dependent receptor
G7047_RS02730	COG1132	(ABC) transporter
G7047_RS02795	COG2003	Belongs to the UPF0758 family
G7047_RS02885	COG1475	DNA binding
G7047_RS02985	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G7047_RS02995	COG0277	FAD linked oxidase domain protein
G7047_RS03005	COG1295	ribonuclease BN
G7047_RS03030	COG1840	ABC-type Fe3 transport system, periplasmic component
G7047_RS03035	COG1178	ABC-type Fe3 transport system permease component
G7047_RS03040	COG3842	ATPase activity
G7047_RS03050	COG0560	Phosphoserine phosphatase
G7047_RS03060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7047_RS03065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G7047_RS03085	COG0544	peptidyl-prolyl cis-trans isomerase activity
G7047_RS03090	COG0740	serine-type endopeptidase activity
G7047_RS03095	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G7047_RS03100	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G7047_RS03130	COG1451	nucleotide metabolic process
G7047_RS03135	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G7047_RS03150	COG0431	NADPH-dependent FMN reductase
G7047_RS03170	COG0154	amidase activity
G7047_RS03195	COG0114	fumarate hydratase activity
G7047_RS03205	COG0745	RESPONSE REGULATOR receiver
G7047_RS03210	COG2205	protein histidine kinase activity
G7047_RS03215	COG2113	Glycine betaine
G7047_RS03220	COG2113	Glycine betaine
G7047_RS03225	COG4176	ABC-type proline glycine betaine transport system permease component
G7047_RS03230	COG4175	Glycine betaine
G7047_RS03235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS03260	COG0559	Belongs to the binding-protein-dependent transport system permease family
G7047_RS03280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G7047_RS03305	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G7047_RS03315	COG4654	Cytochrome c, class I
G7047_RS03325	COG0129	dihydroxy-acid dehydratase activity
G7047_RS03330	COG1335	isochorismatase
G7047_RS03340	COG0583	DNA-binding transcription factor activity
G7047_RS03360	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G7047_RS03365	COG2267	carboxylic ester hydrolase activity
G7047_RS03390	COG1414	Transcriptional regulator
G7047_RS03395	COG1802	Transcriptional regulator
G7047_RS03415	COG1024	Enoyl-CoA hydratase
G7047_RS03430	COG0318	PFAM AMP-dependent synthetase and ligase
G7047_RS03445	COG2217	Heavy metal translocating P-type atpase
G7047_RS03455	COG3278	Belongs to the heme-copper respiratory oxidase family
G7047_RS03475	COG0348	domain, Protein
G7047_RS03490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G7047_RS03515	COG4206	TonB-dependent receptor
G7047_RS03525	COG4607	ABC-type enterochelin transport system periplasmic component
G7047_RS03530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G7047_RS03535	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
G7047_RS03540	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
G7047_RS03545	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
G7047_RS03555	COG1492	cobalamin metabolic process
G7047_RS03560	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
G7047_RS03570	COG0477	Major facilitator Superfamily
G7047_RS03575	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G7047_RS03595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G7047_RS03600	COG2900	Belongs to the SlyX family
G7047_RS03605	COG0667	Aldo Keto reductase
G7047_RS03610	COG0583	DNA-binding transcription factor activity
G7047_RS03620	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS03625	COG3530	Putative quorum-sensing-regulated virulence factor
G7047_RS03635	COG1882	Formate acetyltransferase
G7047_RS03650	COG3842	ATPase activity
G7047_RS03655	COG1840	ABC-type Fe3 transport system, periplasmic component
G7047_RS03685	COG0583	DNA-binding transcription factor activity
G7047_RS03705	COG1464	Belongs to the NlpA lipoprotein family
G7047_RS03710	COG0560	Phosphoserine phosphatase
G7047_RS03725	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G7047_RS03730	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G7047_RS03730	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
G7047_RS03735	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
G7047_RS03735	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G7047_RS03745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G7047_RS03750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7047_RS03755	COG2205	protein histidine kinase activity
G7047_RS03760	COG0745	RESPONSE REGULATOR receiver
G7047_RS03780	COG0517	IMP dehydrogenase activity
G7047_RS03785	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G7047_RS03790	COG0655	NAD(P)H dehydrogenase (quinone) activity
G7047_RS03795	COG1538	Outer membrane efflux protein
G7047_RS03800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7047_RS03805	COG1136	(ABC) transporter
G7047_RS03805	COG0577	efflux transmembrane transporter activity
G7047_RS03810	COG0577	efflux transmembrane transporter activity
G7047_RS03810	COG1136	(ABC) transporter
G7047_RS03830	COG0683	leucine binding
G7047_RS03840	COG2951	lytic endotransglycosylase activity
G7047_RS03855	COG0714	Associated with various cellular activities
G7047_RS03870	COG3264	Mechanosensitive ion channel
G7047_RS03870	COG1196	nuclear chromosome segregation
G7047_RS03885	COG1960	acyl-CoA dehydrogenase activity
G7047_RS03895	COG0477	Major facilitator Superfamily
G7047_RS03905	COG4988	ABC transporter
G7047_RS03910	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
G7047_RS03915	COG1271	oxidase subunit
G7047_RS03920	COG1294	oxidase, subunit
G7047_RS03935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G7047_RS03945	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
G7047_RS03950	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
G7047_RS03965	COG0372	Belongs to the citrate synthase family
G7047_RS03970	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
G7047_RS03975	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G7047_RS03980	COG1053	succinate dehydrogenase
G7047_RS03990	COG2009	succinate dehydrogenase
G7047_RS03995	COG2188	Transcriptional regulator
G7047_RS04000	COG0039	L-malate dehydrogenase activity
G7047_RS04005	COG4106	trans-aconitate 2-methyltransferase activity
G7047_RS04045	COG0583	DNA-binding transcription factor activity
G7047_RS04050	COG1960	acyl-CoA dehydrogenase activity
G7047_RS04060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS04085	COG2954	triphosphatase activity
G7047_RS04090	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
G7047_RS04105	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G7047_RS04110	COG1845	cytochrome c oxidase, subunit III
G7047_RS04115	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G7047_RS04120	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G7047_RS04125	COG0477	Major facilitator Superfamily
G7047_RS04150	COG0824	Thioesterase
G7047_RS04155	COG0436	Aminotransferase
G7047_RS04160	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G7047_RS04165	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G7047_RS04180	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS04185	COG2918	glutathione biosynthetic process
G7047_RS04195	COG1752	Esterase of the alpha-beta hydrolase superfamily
G7047_RS04220	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
G7047_RS04235	COG0564	pseudouridine synthase activity
G7047_RS04255	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS04260	COG1024	Enoyl-CoA hydratase
G7047_RS04265	COG0583	DNA-binding transcription factor activity
G7047_RS04285	COG1960	acyl-CoA dehydrogenase activity
G7047_RS04290	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G7047_RS04305	COG3064	Membrane
G7047_RS04310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G7047_RS04315	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G7047_RS04320	COG0670	Belongs to the BI1 family
G7047_RS04325	COG3193	protein, possibly involved in utilization of glycolate and propanediol
G7047_RS04360	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G7047_RS04370	COG2224	Isocitrate lyase
G7047_RS04380	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G7047_RS04385	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G7047_RS04390	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G7047_RS04395	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G7047_RS04400	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G7047_RS04405	COG0072	phenylalanine-tRNA ligase activity
G7047_RS04405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G7047_RS04410	COG0776	regulation of translation
G7047_RS04415	COG0789	Transcriptional regulator
G7047_RS04450	COG2099	Precorrin-6x reductase
G7047_RS04465	COG2875	Belongs to the precorrin methyltransferase family
G7047_RS04480	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
G7047_RS04485	COG0583	DNA-binding transcription factor activity
G7047_RS04495	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G7047_RS04505	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G7047_RS04515	COG0583	DNA-binding transcription factor activity
G7047_RS04520	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS04525	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G7047_RS04550	COG0776	regulation of translation
G7047_RS04555	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G7047_RS04560	COG0322	excinuclease ABC activity
G7047_RS04590	COG0583	DNA-binding transcription factor activity
G7047_RS04615	COG2159	amidohydrolase
G7047_RS04625	COG2271	Major facilitator Superfamily
G7047_RS04630	COG3384	dioxygenase
G7047_RS04640	COG0028	Belongs to the TPP enzyme family
G7047_RS04675	COG2706	6-phosphogluconolactonase activity
G7047_RS04680	COG4946	Tricorn protease homolog
G7047_RS04680	COG1506	peptidase
G7047_RS04680	COG0823	Involved in the tonB-independent uptake of proteins
G7047_RS04685	COG1012	belongs to the aldehyde dehydrogenase family
G7047_RS04700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS04705	COG0604	alcohol dehydrogenase
G7047_RS04710	COG1960	acyl-CoA dehydrogenase activity
G7047_RS04715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS04720	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS04735	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS04820	COG0513	Belongs to the DEAD box helicase family
G7047_RS04825	COG0488	(ABC) transporter
G7047_RS04840	COG3191	aminopeptidase activity
G7047_RS04855	COG1464	Belongs to the NlpA lipoprotein family
G7047_RS04875	COG0129	dihydroxy-acid dehydratase activity
G7047_RS04890	COG0519	Catalyzes the synthesis of GMP from XMP
G7047_RS04890	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G7047_RS04895	COG0582	viral genome integration into host DNA
G7047_RS04940	COG4372	Transposase
G7047_RS04970	COG1476	TRANSCRIPTIONal
G7047_RS04980	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
G7047_RS05060	COG0640	Transcriptional regulator
G7047_RS05065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G7047_RS05070	COG0506	proline dehydrogenase activity
G7047_RS05070	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G7047_RS05070	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G7047_RS05090	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G7047_RS05150	COG0583	DNA-binding transcription factor activity
G7047_RS05180	COG3618	amidohydrolase
G7047_RS05195	COG1522	sequence-specific DNA binding
G7047_RS05200	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
G7047_RS05210	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS05225	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G7047_RS05245	COG0215	cysteine-tRNA ligase activity
G7047_RS05255	COG0825	malonyl-CoA metabolic process
G7047_RS05260	COG0037	tRNA processing
G7047_RS05280	COG2267	carboxylic ester hydrolase activity
G7047_RS05285	COG1902	pentaerythritol trinitrate reductase activity
G7047_RS05290	COG4221	oxidoreductase activity
G7047_RS05295	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS05300	COG0604	alcohol dehydrogenase
G7047_RS05305	COG1309	transcriptional regulator
G7047_RS05320	COG0583	DNA-binding transcription factor activity
G7047_RS05325	COG2814	Major facilitator Superfamily
G7047_RS05330	COG0431	NADPH-dependent FMN reductase
G7047_RS05415	COG4372	Transposase
G7047_RS05485	COG1414	Transcriptional regulator
G7047_RS05495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G7047_RS05515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G7047_RS05520	COG0179	Fumarylacetoacetate (FAA) hydrolase
G7047_RS05530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G7047_RS05540	COG2814	Major facilitator Superfamily
G7047_RS05605	COG2186	Transcriptional regulator
G7047_RS05615	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G7047_RS05625	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
G7047_RS05640	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
G7047_RS05645	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
G7047_RS05650	COG0298	carbon dioxide binding
G7047_RS05655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G7047_RS05660	COG1773	rubredoxin
G7047_RS05665	COG1773	rubredoxin
G7047_RS05670	COG1773	rubredoxin
G7047_RS05675	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
G7047_RS05680	COG0375	protein maturation
G7047_RS05685	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
G7047_RS05690	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
G7047_RS05695	COG0298	carbon dioxide binding
G7047_RS05700	COG0409	Hydrogenase expression formation protein
G7047_RS05705	COG0309	Hydrogenase expression formation protein (HypE)
G7047_RS05710	COG2204	response regulator
G7047_RS05760	COG1309	transcriptional regulator
G7047_RS05765	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G7047_RS05770	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G7047_RS05775	COG1703	isobutyryl-CoA mutase activity
G7047_RS05835	COG1959	2 iron, 2 sulfur cluster binding
G7047_RS05845	COG0688	phosphatidylethanolamine metabolic process
G7047_RS05850	COG0517	IMP dehydrogenase activity
G7047_RS05850	COG1125	glycine betaine transport
G7047_RS05855	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G7047_RS05885	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G7047_RS05895	COG2917	probably involved in intracellular septation
G7047_RS05900	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G7047_RS05905	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
G7047_RS05910	COG0318	PFAM AMP-dependent synthetase and ligase
G7047_RS05915	COG0559	Belongs to the binding-protein-dependent transport system permease family
G7047_RS05935	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G7047_RS05940	COG1250	3-hydroxyacyl-CoA dehydrogenase
G7047_RS05940	COG1024	Enoyl-CoA hydratase
G7047_RS05945	COG0183	Belongs to the thiolase family
G7047_RS05950	COG1960	acyl-CoA dehydrogenase activity
G7047_RS05955	COG1840	ABC-type Fe3 transport system, periplasmic component
G7047_RS05960	COG1178	ABC-type Fe3 transport system permease component
G7047_RS05965	COG3842	ATPase activity
G7047_RS05975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G7047_RS05980	COG0235	Class ii aldolase
G7047_RS05990	COG0601	transmembrane transport
G7047_RS05995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G7047_RS06000	COG4172	Belongs to the ABC transporter superfamily
G7047_RS06005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G7047_RS06040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G7047_RS06055	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
G7047_RS06065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G7047_RS06075	COG2814	Major facilitator Superfamily
G7047_RS06080	COG1566	PFAM secretion protein HlyD family protein
G7047_RS06130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G7047_RS06135	COG0642	Histidine kinase
G7047_RS06145	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS06160	COG0183	Belongs to the thiolase family
G7047_RS06190	COG0318	PFAM AMP-dependent synthetase and ligase
G7047_RS06210	COG0477	Major facilitator Superfamily
G7047_RS06235	COG4654	Cytochrome c, class I
G7047_RS06240	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G7047_RS06245	COG4654	Cytochrome c, class I
G7047_RS06270	COG0737	Belongs to the 5'-nucleotidase family
G7047_RS06275	COG2391	methyltransferase activity
G7047_RS06315	COG0625	glutathione transferase activity
G7047_RS06320	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
G7047_RS06325	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
G7047_RS06330	COG1770	oligopeptidase
G7047_RS06355	COG1011	Hydrolase
G7047_RS06390	COG1125	glycine betaine transport
G7047_RS06390	COG0517	IMP dehydrogenase activity
G7047_RS06395	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G7047_RS06400	COG0372	Belongs to the citrate synthase family
G7047_RS06405	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS06410	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G7047_RS06415	COG1797	cobyrinic acid a,c-diamide synthase activity
G7047_RS06420	COG1595	DNA-templated transcription, initiation
G7047_RS06425	COG3712	iron ion homeostasis
G7047_RS06440	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G7047_RS06445	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G7047_RS06450	COG0741	lytic transglycosylase activity
G7047_RS06495	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G7047_RS06495	COG2010	Cytochrome c
G7047_RS06505	COG0779	Required for maturation of 30S ribosomal subunits
G7047_RS06510	COG0195	Participates in both transcription termination and antitermination
G7047_RS06515	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
G7047_RS06520	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G7047_RS06525	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G7047_RS06535	COG0004	ammonium transporteR
G7047_RS06540	COG0683	leucine binding
G7047_RS06545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS06590	COG1024	Enoyl-CoA hydratase
G7047_RS06595	COG1858	cytochrome C peroxidase
G7047_RS06600	COG4771	TonB-dependent receptor
G7047_RS06605	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G7047_RS06610	COG2867	negative regulation of translational initiation
G7047_RS06625	COG0390	transport system, permease component
G7047_RS06630	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G7047_RS06650	COG2132	Multicopper oxidase
G7047_RS06670	COG2267	carboxylic ester hydrolase activity
G7047_RS06675	COG0346	lactoylglutathione lyase activity
G7047_RS06690	COG0583	DNA-binding transcription factor activity
G7047_RS06710	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G7047_RS06715	COG0477	Major facilitator Superfamily
G7047_RS06745	COG1309	transcriptional regulator
G7047_RS06780	COG4638	Rieske (2fe-2S)
G7047_RS06785	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS06795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G7047_RS06815	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
G7047_RS06835	COG1607	acyl-coa hydrolase
G7047_RS06850	COG2828	Protein conserved in bacteria
G7047_RS06855	COG1741	Belongs to the pirin family
G7047_RS06860	COG0583	DNA-binding transcription factor activity
G7047_RS06885	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G7047_RS06890	COG4605	iron ion homeostasis
G7047_RS06895	COG4604	ABC transporter, ATP-binding protein
G7047_RS06900	COG4607	ABC-type enterochelin transport system periplasmic component
G7047_RS06905	COG4774	siderophore transport
G7047_RS06910	COG5001	Diguanylate cyclase
G7047_RS06910	COG2203	Gaf domain
G7047_RS06910	COG4251	negative regulation of phosphorylation
G7047_RS06910	COG3706	GGDEF domain
G7047_RS06930	COG1917	Cupin 2, conserved barrel domain protein
G7047_RS06945	COG3971	2-oxopent-4-enoate hydratase activity
G7047_RS06960	COG2814	Major facilitator Superfamily
G7047_RS06965	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G7047_RS06970	COG1802	Transcriptional regulator
G7047_RS06985	COG4120	Belongs to the binding-protein-dependent transport system permease family
G7047_RS06995	COG0415	Belongs to the DNA photolyase family
G7047_RS07015	COG1960	acyl-CoA dehydrogenase activity
G7047_RS07025	COG2175	clavaminate synthase activity
G7047_RS07045	COG0318	PFAM AMP-dependent synthetase and ligase
G7047_RS07080	COG0789	Transcriptional regulator
G7047_RS07085	COG3246	L-lysine catabolic process to acetate
G7047_RS07090	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS07100	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS07105	COG3246	L-lysine catabolic process to acetate
G7047_RS07115	COG0745	RESPONSE REGULATOR receiver
G7047_RS07120	COG2205	protein histidine kinase activity
G7047_RS07125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7047_RS07130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G7047_RS07175	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G7047_RS07180	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G7047_RS07185	COG0470	DNA polymerase III
G7047_RS07195	COG0084	hydrolase, TatD family'
G7047_RS07205	COG1132	(ABC) transporter
G7047_RS07210	COG0823	Involved in the tonB-independent uptake of proteins
G7047_RS07225	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G7047_RS07240	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
G7047_RS07245	COG1216	Glycosyl transferase, family 2
G7047_RS07245	COG0463	Glycosyl transferase, family 2
G7047_RS07270	COG0604	alcohol dehydrogenase
G7047_RS07270	COG3321	synthase
G7047_RS07270	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS07275	COG1733	regulation of RNA biosynthetic process
G7047_RS07285	COG1090	epimerase
G7047_RS07295	COG5000	phosphorelay sensor kinase activity
G7047_RS07305	COG2814	Major facilitator Superfamily
G7047_RS07335	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
G7047_RS07340	COG3118	belongs to the thioredoxin family
G7047_RS07385	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G7047_RS07390	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G7047_RS07400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G7047_RS07405	COG1388	LysM domain
G7047_RS07405	COG0741	lytic transglycosylase activity
G7047_RS07410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G7047_RS07415	COG2226	methyltransferase
G7047_RS07420	COG0328	RNA-DNA hybrid ribonuclease activity
G7047_RS07430	COG0303	'Molybdopterin
G7047_RS07440	COG0746	molybdenum cofactor guanylyltransferase activity
G7047_RS07445	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G7047_RS07465	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G7047_RS07470	COG0835	chemotaxis
G7047_RS07485	COG0347	Belongs to the P(II) protein family
G7047_RS07490	COG0559	Belongs to the binding-protein-dependent transport system permease family
G7047_RS07515	COG0318	PFAM AMP-dependent synthetase and ligase
G7047_RS07530	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
G7047_RS07555	COG0028	Belongs to the TPP enzyme family
G7047_RS07560	COG0440	acetolactate synthase activity
G7047_RS07565	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G7047_RS07570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G7047_RS07575	COG1686	Belongs to the peptidase S11 family
G7047_RS07580	COG1414	Transcriptional regulator
G7047_RS07605	COG3842	ATPase activity
G7047_RS07620	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS07625	COG1960	acyl-CoA dehydrogenase activity
G7047_RS07650	COG1454	alcohol dehydrogenase
G7047_RS07660	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G7047_RS07670	COG0583	DNA-binding transcription factor activity
G7047_RS07690	COG1960	acyl-CoA dehydrogenase activity
G7047_RS07700	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS07705	COG2951	lytic endotransglycosylase activity
G7047_RS07710	COG2925	Exonuclease
G7047_RS07720	COG0628	permease
G7047_RS07730	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G7047_RS07740	COG0625	glutathione transferase activity
G7047_RS07750	COG0583	DNA-binding transcription factor activity
G7047_RS07755	COG0433	COG0433 Predicted ATPase
G7047_RS07760	COG0217	transcriptional regulatory protein
G7047_RS07765	COG0151	Belongs to the GarS family
G7047_RS07770	COG0408	coproporphyrinogen oxidase activity
G7047_RS07775	COG0799	negative regulation of ribosome biogenesis
G7047_RS07780	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
G7047_RS07785	COG0424	maF-like protein
G7047_RS07805	COG3256	nitric oxide reductase
G7047_RS07810	COG2010	Cytochrome c
G7047_RS07820	COG1845	cytochrome c oxidase, subunit III
G7047_RS07850	COG3391	amine dehydrogenase activity
G7047_RS07855	COG2010	Cytochrome c
G7047_RS07865	COG1648	precorrin-2 dehydrogenase activity
G7047_RS07865	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G7047_RS07870	COG1530	ribonuclease E activity
G7047_RS07880	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS07895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS07905	COG1024	Enoyl-CoA hydratase
G7047_RS07910	COG0318	PFAM AMP-dependent synthetase and ligase
G7047_RS07915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G7047_RS07925	COG2197	response regulator
G7047_RS07930	COG0436	Aminotransferase
G7047_RS07935	COG0583	DNA-binding transcription factor activity
G7047_RS07955	COG1477	protein flavinylation
G7047_RS07960	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G7047_RS07980	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G7047_RS08000	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G7047_RS08015	COG0589	response to stress
G7047_RS08030	COG0183	Belongs to the thiolase family
G7047_RS08035	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS08040	COG2207	Transcriptional regulator
G7047_RS08040	COG1917	Cupin 2, conserved barrel domain protein
G7047_RS08065	COG0559	Belongs to the binding-protein-dependent transport system permease family
G7047_RS08075	COG0564	pseudouridine synthase activity
G7047_RS08080	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G7047_RS08080	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G7047_RS08085	COG0509	glycine decarboxylation via glycine cleavage system
G7047_RS08090	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G7047_RS08105	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G7047_RS08115	COG0833	amino acid
G7047_RS08150	COG0642	Histidine kinase
G7047_RS08185	COG1022	Amp-dependent synthetase and ligase
G7047_RS08190	COG1802	Transcriptional regulator
G7047_RS08195	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G7047_RS08195	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G7047_RS08200	COG1703	isobutyryl-CoA mutase activity
G7047_RS08205	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G7047_RS08210	COG4770	biotin carboxylase activity
G7047_RS08220	COG0583	DNA-binding transcription factor activity
G7047_RS08230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS08240	COG0730	response to heat
G7047_RS08260	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
G7047_RS08285	COG3237	CsbD-like
G7047_RS08300	COG0583	DNA-binding transcription factor activity
G7047_RS08305	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS08315	COG0183	Belongs to the thiolase family
G7047_RS08325	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G7047_RS08330	COG1960	acyl-CoA dehydrogenase activity
G7047_RS08335	COG1960	acyl-CoA dehydrogenase activity
G7047_RS08360	COG1024	Enoyl-CoA hydratase
G7047_RS08370	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G7047_RS08410	COG0583	DNA-binding transcription factor activity
G7047_RS08440	COG1024	Enoyl-CoA hydratase
G7047_RS08445	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS08455	COG1960	acyl-CoA dehydrogenase activity
G7047_RS08470	COG1960	acyl-CoA dehydrogenase activity
G7047_RS08480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G7047_RS08485	COG1960	acyl-CoA dehydrogenase activity
G7047_RS08495	COG0318	PFAM AMP-dependent synthetase and ligase
G7047_RS08540	COG4772	TonB-dependent receptor
G7047_RS08570	COG1484	DNA-dependent DNA replication
G7047_RS08580	COG0583	DNA-binding transcription factor activity
G7047_RS08585	COG1960	acyl-CoA dehydrogenase activity
G7047_RS08590	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
G7047_RS08595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS08600	COG2301	Belongs to the HpcH HpaI aldolase family
G7047_RS08610	COG0477	Major facilitator Superfamily
G7047_RS08620	COG0235	Class ii aldolase
G7047_RS08625	COG2084	Dehydrogenase
G7047_RS08630	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G7047_RS08650	COG1012	belongs to the aldehyde dehydrogenase family
G7047_RS08700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS08705	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G7047_RS08705	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G7047_RS08710	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G7047_RS08710	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G7047_RS08715	COG1024	Enoyl-CoA hydratase
G7047_RS08730	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G7047_RS08780	COG0318	PFAM AMP-dependent synthetase and ligase
G7047_RS08835	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G7047_RS08840	COG0346	lactoylglutathione lyase activity
G7047_RS08855	COG0778	Nitroreductase
G7047_RS08860	COG2186	Transcriptional regulator
G7047_RS08900	COG1024	Enoyl-CoA hydratase
G7047_RS08900	COG1250	3-hydroxyacyl-CoA dehydrogenase
G7047_RS08905	COG1960	acyl-CoA dehydrogenase activity
G7047_RS08910	COG1960	acyl-CoA dehydrogenase activity
G7047_RS08915	COG0318	PFAM AMP-dependent synthetase and ligase
G7047_RS08925	COG1902	pentaerythritol trinitrate reductase activity
G7047_RS08930	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS08950	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G7047_RS08960	COG1960	acyl-CoA dehydrogenase activity
G7047_RS09005	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS09010	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS09030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G7047_RS09035	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS09040	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS09045	COG1012	belongs to the aldehyde dehydrogenase family
G7047_RS09080	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G7047_RS09095	COG0583	DNA-binding transcription factor activity
G7047_RS09100	COG3706	GGDEF domain
G7047_RS09105	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G7047_RS09110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G7047_RS09115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G7047_RS09120	COG0583	DNA-binding transcription factor activity
G7047_RS09125	COG1741	Belongs to the pirin family
G7047_RS09130	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
G7047_RS09135	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
G7047_RS09140	COG3171	Protein conserved in bacteria
G7047_RS09185	COG1960	acyl-CoA dehydrogenase activity
G7047_RS09200	COG0583	DNA-binding transcription factor activity
G7047_RS09205	COG1113	amino acid transport
G7047_RS09210	COG2814	Major facilitator Superfamily
G7047_RS09215	COG1132	(ABC) transporter
G7047_RS09225	COG1742	UPF0060 membrane protein
G7047_RS09230	COG1196	nuclear chromosome segregation
G7047_RS09240	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G7047_RS09250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G7047_RS09280	COG3243	poly(R)-hydroxyalkanoic acid synthase
G7047_RS09285	COG0183	Belongs to the thiolase family
G7047_RS09290	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS09295	COG0488	(ABC) transporter
G7047_RS09305	COG2890	protein-(glutamine-N5) methyltransferase activity
G7047_RS09310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G7047_RS09320	COG2171	N-acyltransferase activity
G7047_RS09325	COG0436	Aminotransferase
G7047_RS09330	COG2878	Part of a membrane complex involved in electron transport
G7047_RS09355	COG1252	NADH dehydrogenase
G7047_RS09380	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS09400	COG0587	DNA-directed DNA polymerase activity
G7047_RS09415	COG1960	acyl-CoA dehydrogenase activity
G7047_RS09420	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS09435	COG0583	DNA-binding transcription factor activity
G7047_RS09460	COG2084	Dehydrogenase
G7047_RS09475	COG2084	Dehydrogenase
G7047_RS09500	COG2197	response regulator
G7047_RS09520	COG4372	Transposase
G7047_RS09525	COG4585	Histidine kinase
G7047_RS09530	COG2982	Protein involved in outer membrane biogenesis
G7047_RS09540	COG0564	pseudouridine synthase activity
G7047_RS09605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G7047_RS09620	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
G7047_RS09710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G7047_RS09715	COG1960	acyl-CoA dehydrogenase activity
G7047_RS09740	COG1484	DNA-dependent DNA replication
G7047_RS09770	COG0559	Belongs to the binding-protein-dependent transport system permease family
G7047_RS09795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS09805	COG1960	acyl-CoA dehydrogenase activity
G7047_RS09810	COG1024	Enoyl-CoA hydratase
G7047_RS09815	COG1902	pentaerythritol trinitrate reductase activity
G7047_RS09840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS09865	COG1960	acyl-CoA dehydrogenase activity
G7047_RS09875	COG1024	Enoyl-CoA hydratase
G7047_RS09880	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS09900	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS09905	COG1609	Transcriptional regulator
G7047_RS10000	COG1522	sequence-specific DNA binding
G7047_RS10015	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS10025	COG0183	Belongs to the thiolase family
G7047_RS10035	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
G7047_RS10040	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
G7047_RS10060	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS10070	COG1012	belongs to the aldehyde dehydrogenase family
G7047_RS10075	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS10110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7047_RS10115	COG0577	efflux transmembrane transporter activity
G7047_RS10115	COG1136	(ABC) transporter
G7047_RS10120	COG1538	Outer membrane efflux protein
G7047_RS10135	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G7047_RS10140	COG4566	intracellular signal transduction
G7047_RS10155	COG0508	dehydrogenase complex catalyzes the overall conversion of
G7047_RS10160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G7047_RS10185	COG0583	DNA-binding transcription factor activity
G7047_RS10190	COG1960	acyl-CoA dehydrogenase activity
G7047_RS10200	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS10240	COG1012	belongs to the aldehyde dehydrogenase family
G7047_RS10255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G7047_RS10270	COG0791	NLP P60 protein
G7047_RS10275	COG2133	pyrroloquinoline quinone binding
G7047_RS10300	COG0697	spore germination
G7047_RS10305	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G7047_RS10310	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
G7047_RS10325	COG0045	succinate-CoA ligase (ADP-forming) activity
G7047_RS10325	COG1042	CoA-binding domain protein
G7047_RS10325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G7047_RS10345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS10350	COG0583	DNA-binding transcription factor activity
G7047_RS10355	COG1960	acyl-CoA dehydrogenase activity
G7047_RS10395	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS10405	COG2030	dehydratase
G7047_RS10410	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS10415	COG0579	oxidoreductase
G7047_RS10435	COG0167	dihydroorotate dehydrogenase activity
G7047_RS10440	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
G7047_RS10455	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G7047_RS10460	COG1309	transcriptional regulator
G7047_RS10465	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G7047_RS10475	COG4771	TonB-dependent receptor
G7047_RS10495	COG0259	pyridoxamine-phosphate oxidase activity
G7047_RS10500	COG2032	superoxide dismutase activity
G7047_RS10515	COG1609	Transcriptional regulator
G7047_RS10520	COG3265	gluconokinase activity
G7047_RS10525	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
G7047_RS10530	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G7047_RS10535	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G7047_RS10545	COG0800	Aldolase
G7047_RS10550	COG0724	RNA recognition motif
G7047_RS10555	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G7047_RS10565	COG0346	lactoylglutathione lyase activity
G7047_RS10570	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS10620	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G7047_RS10620	COG0515	serine threonine protein kinase
G7047_RS10635	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS10640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G7047_RS10650	COG1414	Transcriptional regulator
G7047_RS10655	COG1404	Belongs to the peptidase S8 family
G7047_RS10820	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G7047_RS10845	COG4585	Histidine kinase
G7047_RS10850	COG1960	acyl-CoA dehydrogenase activity
G7047_RS10855	COG1960	acyl-CoA dehydrogenase activity
G7047_RS10860	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS10870	COG0183	Belongs to the thiolase family
G7047_RS10880	COG1960	acyl-CoA dehydrogenase activity
G7047_RS10890	COG2070	2-Nitropropane dioxygenase
G7047_RS10895	COG1024	Enoyl-CoA hydratase
G7047_RS10910	COG0346	lactoylglutathione lyase activity
G7047_RS10915	COG1902	pentaerythritol trinitrate reductase activity
G7047_RS10925	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS10930	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS10935	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G7047_RS10950	COG3415	Transposase
G7047_RS10950	COG2801	Transposase and inactivated derivatives
G7047_RS10975	COG0583	DNA-binding transcription factor activity
G7047_RS10995	COG3833	ABC-type maltose transport systems, permease component
G7047_RS11000	COG3842	ATPase activity
G7047_RS11015	COG0735	belongs to the Fur family
G7047_RS11030	COG0346	lactoylglutathione lyase activity
G7047_RS11040	COG0798	PFAM Bile acid sodium symporter
G7047_RS11045	COG4774	siderophore transport
G7047_RS11050	COG3128	pkhd-type hydroxylase
G7047_RS11075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS11080	COG1960	acyl-CoA dehydrogenase activity
G7047_RS11090	COG1960	acyl-CoA dehydrogenase activity
G7047_RS11095	COG0183	Belongs to the thiolase family
G7047_RS11120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G7047_RS11125	COG0508	dehydrogenase complex catalyzes the overall conversion of
G7047_RS11130	COG1024	Enoyl-CoA hydratase
G7047_RS11135	COG0022	dehydrogenase e1 component
G7047_RS11140	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G7047_RS11165	COG1960	acyl-CoA dehydrogenase activity
G7047_RS11195	COG3829	transcription factor binding
G7047_RS11205	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G7047_RS11205	COG2755	lipolytic protein G-D-S-L family
G7047_RS11210	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G7047_RS11210	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G7047_RS11215	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS11230	COG0251	oxidation-reduction process
G7047_RS11235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G7047_RS11285	COG0251	oxidation-reduction process
G7047_RS11300	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
G7047_RS11305	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G7047_RS11310	COG4208	sulfate ABC transporter
G7047_RS11315	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
G7047_RS11320	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G7047_RS11325	COG0583	DNA-binding transcription factor activity
G7047_RS11330	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G7047_RS11335	COG0513	Belongs to the DEAD box helicase family
G7047_RS11340	COG1346	cytolysis
G7047_RS11350	COG1122	ATPase activity
G7047_RS11355	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
G7047_RS11360	COG1268	BioY protein
G7047_RS11365	COG0318	PFAM AMP-dependent synthetase and ligase
G7047_RS11375	COG0778	Nitroreductase
G7047_RS11375	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
G7047_RS11385	COG1464	Belongs to the NlpA lipoprotein family
G7047_RS11405	COG2011	ABC-type metal ion transport system permease component
G7047_RS11410	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G7047_RS11440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G7047_RS11465	COG0583	DNA-binding transcription factor activity
G7047_RS11485	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G7047_RS11490	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
G7047_RS11495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G7047_RS11495	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
G7047_RS11530	COG0175	sulfate reduction
G7047_RS11535	COG2895	sulfate adenylyltransferase (ATP) activity
G7047_RS11540	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G7047_RS11545	COG0492	ferredoxin-NADP+ reductase activity
G7047_RS11570	COG0351	phosphomethylpyrimidine kinase
G7047_RS11585	COG2022	thiamine diphosphate biosynthetic process
G7047_RS11595	COG1250	3-hydroxyacyl-CoA dehydrogenase
G7047_RS11600	COG1024	Enoyl-CoA hydratase
G7047_RS11625	COG0542	response to heat
G7047_RS11630	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G7047_RS11645	COG1199	ATP-dependent helicase activity
G7047_RS11660	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G7047_RS11665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G7047_RS11670	COG0508	dehydrogenase complex catalyzes the overall conversion of
G7047_RS11675	COG0567	Dehydrogenase, E1 component
G7047_RS11680	COG0628	permease
G7047_RS11685	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS11700	COG0583	DNA-binding transcription factor activity
G7047_RS11705	COG0589	response to stress
G7047_RS11710	COG0596	Alpha beta hydrolase
G7047_RS11715	COG4172	Belongs to the ABC transporter superfamily
G7047_RS11720	COG4239	(ABC) transporter, permease
G7047_RS11730	COG4174	ABC transporter (Permease)
G7047_RS11745	COG1414	Transcriptional regulator
G7047_RS11750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G7047_RS11755	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS11760	COG0077	Prephenate dehydratase
G7047_RS11765	COG1982	Orn Lys Arg decarboxylase major
G7047_RS11785	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS11795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G7047_RS11800	COG1116	anion transmembrane transporter activity
G7047_RS12020	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G7047_RS12030	COG0443	Heat shock 70 kDa protein
G7047_RS12035	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
G7047_RS12040	COG0316	Belongs to the HesB IscA family
G7047_RS12045	COG0822	iron-sulfur transferase activity
G7047_RS12050	COG1104	cysteine desulfurase activity
G7047_RS12055	COG1959	2 iron, 2 sulfur cluster binding
G7047_RS12060	COG0556	nucleotide-excision repair
G7047_RS12070	COG3384	dioxygenase
G7047_RS12075	COG1278	Cold shock
G7047_RS12095	COG1739	Uncharacterized protein family UPF0029
G7047_RS12100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G7047_RS12110	COG3550	peptidyl-serine autophosphorylation
G7047_RS12140	COG1643	Atp-dependent helicase
G7047_RS12145	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G7047_RS12150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G7047_RS12165	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
G7047_RS12170	COG4181	ATPase activity
G7047_RS12180	COG0626	cystathionine gamma-synthase activity
G7047_RS12185	COG2823	Periplasmic or secreted lipoprotein
G7047_RS12190	COG0659	secondary active sulfate transmembrane transporter activity
G7047_RS12200	COG1741	Belongs to the pirin family
G7047_RS12225	COG0217	transcriptional regulatory protein
G7047_RS12255	COG1619	proteins homologs of microcin C7 resistance protein MccF
G7047_RS12270	COG1397	ADP-ribosylglycohydrolase
G7047_RS12290	COG0826	peptidase U32
G7047_RS12305	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G7047_RS12310	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
G7047_RS12335	COG4177	L-phenylalanine transmembrane transporter activity
G7047_RS12345	COG0410	ABC transporter
G7047_RS12355	COG3047	cAMP biosynthetic process
G7047_RS12360	COG2354	Protein conserved in bacteria
G7047_RS12365	COG0047	phosphoribosylformylglycinamidine synthase activity
G7047_RS12365	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G7047_RS12375	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
G7047_RS12380	COG0242	peptide deformylase activity
G7047_RS12385	COG2832	Protein of unknown function (DUF454)
G7047_RS12445	COG0583	DNA-binding transcription factor activity
G7047_RS12450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G7047_RS12455	COG1570	exodeoxyribonuclease VII activity
G7047_RS12460	COG0811	peptide transport
G7047_RS12465	COG0848	biopolymer transport protein
G7047_RS12470	COG1663	tetraacyldisaccharide 4'-kinase activity
G7047_RS12475	COG2835	tetraacyldisaccharide 4'-kinase activity
G7047_RS12480	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
G7047_RS12485	COG0563	adenylate kinase activity
G7047_RS12490	COG0252	asparaginase activity
G7047_RS12495	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G7047_RS12515	COG0656	L-ascorbic acid biosynthetic process
G7047_RS12520	COG0583	DNA-binding transcription factor activity
G7047_RS12530	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
G7047_RS12545	COG2183	response to ionizing radiation
G7047_RS12565	COG1522	sequence-specific DNA binding
G7047_RS12570	COG2423	ornithine cyclodeaminase activity
G7047_RS12575	COG2814	Major facilitator Superfamily
G7047_RS12585	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G7047_RS12600	COG2153	protein acetylation
G7047_RS12620	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G7047_RS12645	COG2807	transmembrane transport
G7047_RS12655	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G7047_RS12660	COG1012	belongs to the aldehyde dehydrogenase family
G7047_RS12665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G7047_RS12670	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G7047_RS12675	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G7047_RS12680	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G7047_RS12685	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G7047_RS12690	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G7047_RS12705	COG0750	zinc metalloprotease
G7047_RS12710	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G7047_RS12715	COG0575	Belongs to the CDS family
G7047_RS12720	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G7047_RS12725	COG0233	cytoplasmic translational termination
G7047_RS12730	COG0528	UMP kinase activity
G7047_RS12735	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G7047_RS12740	COG0052	Belongs to the universal ribosomal protein uS2 family
G7047_RS12750	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G7047_RS12750	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G7047_RS12785	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
G7047_RS12790	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G7047_RS12795	COG3135	benzoate transporter
G7047_RS12805	COG2814	Major facilitator Superfamily
G7047_RS12810	COG0251	oxidation-reduction process
G7047_RS12815	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS12835	COG3485	protocatechuate 3,4-dioxygenase
G7047_RS12850	COG2205	protein histidine kinase activity
G7047_RS12875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7047_RS12880	COG0842	Transport permease protein
G7047_RS12880	COG1129	ABC transporter
G7047_RS12885	COG0842	Transport permease protein
G7047_RS12890	COG0254	rRNA binding
G7047_RS12900	COG0534	Mate efflux family protein
G7047_RS12910	COG0745	RESPONSE REGULATOR receiver
G7047_RS12915	COG0704	Plays a role in the regulation of phosphate uptake
G7047_RS12920	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G7047_RS12925	COG0581	inorganic phosphate transmembrane transporter activity
G7047_RS12930	COG0573	inorganic phosphate transmembrane transporter activity
G7047_RS12935	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G7047_RS12960	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G7047_RS12970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G7047_RS12980	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G7047_RS12985	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
G7047_RS12990	COG1534	Rna-binding protein
G7047_RS13005	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G7047_RS13010	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G7047_RS13015	COG0505	Belongs to the CarA family
G7047_RS13025	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G7047_RS13035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G7047_RS13045	COG3485	protocatechuate 3,4-dioxygenase
G7047_RS13065	COG1137	ATPase activity
G7047_RS13090	COG1012	belongs to the aldehyde dehydrogenase family
G7047_RS13105	COG0583	DNA-binding transcription factor activity
G7047_RS13115	COG4172	Belongs to the ABC transporter superfamily
G7047_RS13125	COG0601	transmembrane transport
G7047_RS13130	COG0747	negative chemotaxis
G7047_RS13135	COG3048	D-serine ammonia-lyase activity
G7047_RS13140	COG0583	DNA-binding transcription factor activity
G7047_RS13145	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS13150	COG2188	Transcriptional regulator
G7047_RS13155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS13165	COG1024	Enoyl-CoA hydratase
G7047_RS13175	COG3781	membrane
G7047_RS13195	COG0582	viral genome integration into host DNA
G7047_RS13210	COG4983	Phage plasmid primase, P4 family domain protein
G7047_RS13260	COG3501	Rhs element vgr protein
G7047_RS13280	COG5484	DNA packaging
G7047_RS13280	COG3728	DNA packaging
G7047_RS13315	COG4191	Histidine kinase
G7047_RS13360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G7047_RS13385	COG0582	viral genome integration into host DNA
G7047_RS13660	COG5377	YqaJ viral recombinase family
G7047_RS13675	COG3039	Transposase
G7047_RS13690	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
G7047_RS13695	COG1063	alcohol dehydrogenase
G7047_RS13730	COG4372	Transposase
G7047_RS13770	COG5377	YqaJ viral recombinase family
G7047_RS13805	COG1431	PFAM Stem cell self-renewal protein Piwi
G7047_RS13820	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G7047_RS13835	COG0582	viral genome integration into host DNA
G7047_RS13845	COG0546	phosphoglycolate phosphatase activity
G7047_RS13850	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G7047_RS13865	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G7047_RS13875	COG0287	Prephenate dehydrogenase
G7047_RS13880	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G7047_RS13890	COG0776	regulation of translation
G7047_RS13900	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
G7047_RS13910	COG2111	Na H antiporter
G7047_RS13910	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G7047_RS13915	COG1006	Multisubunit Na H antiporter MnhC subunit
G7047_RS13920	COG0651	ATP synthesis coupled electron transport
G7047_RS13930	COG2212	antiporter activity
G7047_RS13945	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G7047_RS13950	COG1611	Belongs to the LOG family
G7047_RS13970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G7047_RS13980	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
G7047_RS13985	COG0824	Thioesterase
G7047_RS14040	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G7047_RS14060	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
G7047_RS14065	COG0285	dihydrofolate synthase activity
G7047_RS14070	COG1393	Belongs to the ArsC family
G7047_RS14080	COG3123	guanosine phosphorylase activity
G7047_RS14085	COG0137	argininosuccinate synthase activity
G7047_RS14090	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS14100	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G7047_RS14105	COG1666	GTP binding
G7047_RS14120	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
G7047_RS14125	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G7047_RS14130	COG0667	Aldo Keto reductase
G7047_RS14165	COG0308	aminopeptidase N
G7047_RS14170	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
G7047_RS14175	COG0582	viral genome integration into host DNA
G7047_RS14260	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G7047_RS14265	COG3593	DNA synthesis involved in DNA repair
G7047_RS14290	COG0582	viral genome integration into host DNA
G7047_RS14370	COG2766	serine protein kinase
G7047_RS14375	COG2718	Belongs to the UPF0229 family
G7047_RS14380	COG2719	SpoVR family
G7047_RS14390	COG1113	amino acid transport
G7047_RS14410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G7047_RS14415	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS14425	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G7047_RS14450	COG0824	Thioesterase
G7047_RS14465	COG0463	Glycosyl transferase, family 2
G7047_RS14480	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G7047_RS14485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G7047_RS14490	COG0204	Acyl-transferase
G7047_RS14510	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS14520	COG1960	acyl-CoA dehydrogenase activity
G7047_RS14525	COG0318	PFAM AMP-dependent synthetase and ligase
G7047_RS14540	COG3209	COG3209 Rhs family protein
G7047_RS14565	COG3209	COG3209 Rhs family protein
G7047_RS14615	COG1783	phage Terminase large subunit
G7047_RS14640	COG0305	Participates in initiation and elongation during chromosome replication
G7047_RS14715	COG3617	BRO family, N-terminal domain
G7047_RS14740	COG0582	viral genome integration into host DNA
G7047_RS14750	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G7047_RS14760	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS14770	COG0745	RESPONSE REGULATOR receiver
G7047_RS14775	COG2205	protein histidine kinase activity
G7047_RS14780	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G7047_RS14800	COG1607	acyl-coa hydrolase
G7047_RS14810	COG2081	HI0933 family
G7047_RS14820	COG0828	Belongs to the bacterial ribosomal protein bS21 family
G7047_RS14825	COG1610	YqeY-like protein
G7047_RS14830	COG1522	sequence-specific DNA binding
G7047_RS14840	COG0583	DNA-binding transcription factor activity
G7047_RS14845	COG0473	3-isopropylmalate dehydrogenase activity
G7047_RS14885	COG0446	pyridine nucleotide-disulphide oxidoreductase
G7047_RS14900	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G7047_RS14905	COG4521	taurine ABC transporter
G7047_RS14925	COG0312	modulator of DNA gyrase
G7047_RS14935	COG0521	Mo-molybdopterin cofactor biosynthetic process
G7047_RS14940	COG0584	glycerophosphoryl diester phosphodiesterase
G7047_RS14945	COG2814	Major facilitator Superfamily
G7047_RS14955	COG1011	Hydrolase
G7047_RS14960	COG1045	serine acetyltransferase
G7047_RS15025	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
G7047_RS15025	COG3608	succinylglutamate desuccinylase aspartoacylase
G7047_RS15045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G7047_RS15060	COG0583	DNA-binding transcription factor activity
G7047_RS15070	COG2814	Major facilitator Superfamily
G7047_RS15085	COG0179	Fumarylacetoacetate (FAA) hydrolase
G7047_RS15105	COG0318	PFAM AMP-dependent synthetase and ligase
G7047_RS15110	COG0358	DNA primase activity
G7047_RS15115	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G7047_RS15125	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G7047_RS15140	COG3384	dioxygenase
G7047_RS15150	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G7047_RS15165	COG0583	DNA-binding transcription factor activity
G7047_RS15185	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G7047_RS15200	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
G7047_RS15205	COG1032	radical SAM domain protein
G7047_RS15235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G7047_RS15240	COG4558	Periplasmic binding protein
G7047_RS15245	COG3720	iron ion transport
G7047_RS15255	COG3634	alkyl hydroperoxide reductase activity
G7047_RS15260	COG0450	alkyl hydroperoxide reductase
G7047_RS15275	COG1289	transmembrane transporter activity
G7047_RS15280	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
G7047_RS15285	COG0181	hydroxymethylbilane synthase activity
G7047_RS15330	COG0583	DNA-binding transcription factor activity
G7047_RS15340	COG0604	alcohol dehydrogenase
G7047_RS15345	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS15355	COG0525	valine-tRNA ligase activity
G7047_RS15360	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G7047_RS15365	COG0697	spore germination
G7047_RS15370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G7047_RS15375	COG0425	Belongs to the sulfur carrier protein TusA family
G7047_RS15395	COG0778	Nitroreductase
G7047_RS15405	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS15425	COG0604	alcohol dehydrogenase
G7047_RS15430	COG1960	acyl-CoA dehydrogenase activity
G7047_RS15455	COG0583	DNA-binding transcription factor activity
G7047_RS15460	COG1960	acyl-CoA dehydrogenase activity
G7047_RS15465	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS15485	COG2910	NAD(P)H-binding
G7047_RS15490	COG0583	DNA-binding transcription factor activity
G7047_RS15510	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G7047_RS15510	COG0543	2 iron, 2 sulfur cluster binding
G7047_RS15525	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G7047_RS15530	COG0617	tRNA 3'-terminal CCA addition
G7047_RS15535	COG2217	Heavy metal translocating P-type atpase
G7047_RS15540	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G7047_RS15545	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G7047_RS15555	COG0589	response to stress
G7047_RS15570	COG0728	peptidoglycan biosynthetic process
G7047_RS15575	COG0268	Binds directly to 16S ribosomal RNA
G7047_RS15600	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G7047_RS15605	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G7047_RS15620	COG0583	DNA-binding transcription factor activity
G7047_RS15665	COG1053	succinate dehydrogenase
G7047_RS15705	COG0446	pyridine nucleotide-disulphide oxidoreductase
G7047_RS15730	COG0727	PFAM Uncharacterised protein family (UPF0153)
G7047_RS15735	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
G7047_RS15750	COG3483	tryptophan 2,3-dioxygenase activity
G7047_RS15760	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G7047_RS15790	COG1126	abc transporter atp-binding protein
G7047_RS15795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G7047_RS15825	COG1129	ABC transporter
G7047_RS15840	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G7047_RS15845	COG2814	Major facilitator Superfamily
G7047_RS15850	COG5001	Diguanylate cyclase
G7047_RS15850	COG3447	MASE1 domain protein
G7047_RS15850	COG5002	protein histidine kinase activity
G7047_RS15860	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
G7047_RS15875	COG0251	oxidation-reduction process
G7047_RS15890	COG0537	adenosine 5'-monophosphoramidase activity
G7047_RS15900	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G7047_RS15905	COG1136	(ABC) transporter
G7047_RS15935	COG0559	Belongs to the binding-protein-dependent transport system permease family
G7047_RS15975	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
G7047_RS15995	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G7047_RS16000	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G7047_RS16010	COG1722	exodeoxyribonuclease VII activity
G7047_RS16070	COG2308	Evidence 4 Homologs of previously reported genes of
G7047_RS16085	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
G7047_RS16095	COG2197	response regulator
G7047_RS16100	COG4585	Histidine kinase
G7047_RS16105	COG2329	Antibiotic biosynthesis monooxygenase
G7047_RS16120	COG0741	lytic transglycosylase activity
G7047_RS16145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G7047_RS16150	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
G7047_RS16155	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
G7047_RS16170	COG2850	peptidyl-arginine hydroxylation
G7047_RS16175	COG1047	Peptidyl-prolyl cis-trans
G7047_RS16185	COG0756	dUTP diphosphatase activity
G7047_RS16195	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G7047_RS16200	COG0504	CTP synthase activity
G7047_RS16205	COG2877	3-deoxy-8-phosphooctulonate synthase activity
G7047_RS16210	COG0148	phosphopyruvate hydratase activity
G7047_RS16215	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
G7047_RS16225	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
G7047_RS16235	COG2833	Protein of unknown function (DUF455)
G7047_RS16250	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS16255	COG4974	Belongs to the 'phage' integrase family
G7047_RS16260	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS16270	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
G7047_RS16275	COG0802	atpase or kinase
G7047_RS16280	COG0860	N-Acetylmuramoyl-L-alanine amidase
G7047_RS16290	COG0586	Pfam SNARE associated Golgi protein
G7047_RS16295	COG1131	(ABC) transporter
G7047_RS16310	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G7047_RS16320	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G7047_RS16325	COG1280	lysine exporter protein (LysE YggA)
G7047_RS16330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7047_RS16385	COG1007	ATP synthesis coupled electron transport
G7047_RS16400	COG0713	ATP synthesis coupled electron transport
G7047_RS16410	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G7047_RS16415	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G7047_RS16420	COG1034	ATP synthesis coupled electron transport
G7047_RS16435	COG0649	NAD binding
G7047_RS16440	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G7047_RS16445	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G7047_RS16450	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G7047_RS16465	COG0149	triose-phosphate isomerase activity
G7047_RS16470	COG3321	synthase
G7047_RS16470	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS16470	COG0604	alcohol dehydrogenase
G7047_RS16475	COG1185	polyribonucleotide nucleotidyltransferase activity
G7047_RS16480	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G7047_RS16495	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G7047_RS16500	COG1758	RNA polymerase activity
G7047_RS16505	COG0194	GDP metabolic process
G7047_RS16510	COG1561	YicC-like family, N-terminal region
G7047_RS16515	COG0515	serine threonine protein kinase
G7047_RS16515	COG2815	serine threonine protein kinase
G7047_RS16530	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G7047_RS16535	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G7047_RS16545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G7047_RS16560	COG0745	RESPONSE REGULATOR receiver
G7047_RS16565	COG2205	protein histidine kinase activity
G7047_RS16570	COG1414	Transcriptional regulator
G7047_RS16575	COG1012	belongs to the aldehyde dehydrogenase family
G7047_RS16580	COG0318	PFAM AMP-dependent synthetase and ligase
G7047_RS16585	COG2271	Major facilitator Superfamily
G7047_RS16590	COG0582	viral genome integration into host DNA
G7047_RS16685	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
G7047_RS16745	COG1420	regulation of RNA biosynthetic process
G7047_RS16750	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G7047_RS16755	COG0497	DNA recombination
G7047_RS16760	COG1660	Displays ATPase and GTPase activities
G7047_RS16770	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
G7047_RS16775	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G7047_RS16790	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
G7047_RS16800	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G7047_RS16805	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
G7047_RS16810	COG0193	aminoacyl-tRNA hydrolase activity
G7047_RS16820	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G7047_RS16830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G7047_RS16840	COG4608	Belongs to the ABC transporter superfamily
G7047_RS16845	COG0747	negative chemotaxis
G7047_RS16850	COG0154	amidase activity
G7047_RS16855	COG1280	lysine exporter protein (LysE YggA)
G7047_RS16885	COG0302	gtp cyclohydrolase
G7047_RS16910	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G7047_RS16925	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G7047_RS16930	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G7047_RS16945	COG2226	methyltransferase
G7047_RS16965	COG1960	acyl-CoA dehydrogenase activity
G7047_RS16970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G7047_RS16995	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G7047_RS17000	COG1653	transport
G7047_RS17005	COG1175	transmembrane transport
G7047_RS17010	COG0395	ABC-type sugar transport system, permease component
G7047_RS17015	COG3842	ATPase activity
G7047_RS17025	COG0584	glycerophosphoryl diester phosphodiesterase
G7047_RS17030	COG3264	Mechanosensitive ion channel
G7047_RS17030	COG1511	domain protein
G7047_RS17035	COG2375	cellular response to nickel ion
G7047_RS17050	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
G7047_RS17055	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G7047_RS17060	COG2890	protein-(glutamine-N5) methyltransferase activity
G7047_RS17065	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G7047_RS17070	COG1253	flavin adenine dinucleotide binding
G7047_RS17080	COG0442	prolyl-tRNA aminoacylation
G7047_RS17085	COG0494	nUDIX hydrolase
G7047_RS17090	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G7047_RS17095	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G7047_RS17100	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G7047_RS17105	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G7047_RS17110	COG0142	geranyltranstransferase activity
G7047_RS17130	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
G7047_RS17135	COG0237	dephospho-CoA kinase activity
G7047_RS17140	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
G7047_RS17145	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
G7047_RS17150	COG0494	nUDIX hydrolase
G7047_RS17160	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G7047_RS17165	COG0653	protein targeting
G7047_RS17265	COG2969	positive regulation of protein catabolic process
G7047_RS17270	COG0625	glutathione transferase activity
G7047_RS17275	COG2857	Cytochrome c1
G7047_RS17280	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G7047_RS17285	COG0723	plastoquinol--plastocyanin reductase activity
G7047_RS17290	COG1970	mechanosensitive ion channel activity
G7047_RS17295	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G7047_RS17300	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G7047_RS17310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G7047_RS17315	COG0805	protein transport
G7047_RS17320	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G7047_RS17325	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G7047_RS17330	COG0537	adenosine 5'-monophosphoramidase activity
G7047_RS17345	COG0140	phosphoribosyl-ATP diphosphatase activity
G7047_RS17350	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G7047_RS17355	COG0107	imidazoleglycerol-phosphate synthase activity
G7047_RS17365	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G7047_RS17370	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G7047_RS17380	COG0131	Imidazoleglycerol-phosphate dehydratase
G7047_RS17385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G7047_RS17410	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G7047_RS17415	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G7047_RS17425	COG0842	Transport permease protein
G7047_RS17430	COG1131	(ABC) transporter
G7047_RS17450	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G7047_RS17455	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G7047_RS17460	COG1127	ABC transporter
G7047_RS17465	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
G7047_RS17470	COG1126	abc transporter atp-binding protein
G7047_RS17475	COG0765	amino acid transport
G7047_RS17490	COG2814	Major facilitator Superfamily
G7047_RS17495	COG0513	Belongs to the DEAD box helicase family
G7047_RS17500	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
G7047_RS17505	COG0501	Belongs to the peptidase M48B family
G7047_RS17510	COG2154	pterin-4-alpha-carbinolamine dehydratase
G7047_RS17515	COG1162	GTPase activity
G7047_RS17530	COG0745	RESPONSE REGULATOR receiver
G7047_RS17535	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
G7047_RS17545	COG0335	large ribosomal subunit rRNA binding
G7047_RS17550	COG0336	Belongs to the RNA methyltransferase TrmD family
G7047_RS17555	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G7047_RS17560	COG0228	four-way junction DNA binding
G7047_RS17570	COG2314	TM2 domain
G7047_RS17575	COG0306	phosphate transporter
G7047_RS17580	COG1392	Phosphate transport regulator
G7047_RS17605	COG0559	Belongs to the binding-protein-dependent transport system permease family
G7047_RS17610	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G7047_RS17635	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
G7047_RS17640	COG1674	ftsk spoiiie
G7047_RS17645	COG0492	ferredoxin-NADP+ reductase activity
G7047_RS17650	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G7047_RS17655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G7047_RS17670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G7047_RS17670	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G7047_RS17685	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G7047_RS17690	COG3132	Protein of unknown function, DUF480
G7047_RS17695	COG1960	acyl-CoA dehydrogenase activity
G7047_RS17700	COG1960	acyl-CoA dehydrogenase activity
G7047_RS17705	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G7047_RS17710	COG2011	ABC-type metal ion transport system permease component
G7047_RS17715	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G7047_RS17720	COG1464	Belongs to the NlpA lipoprotein family
G7047_RS17730	COG1116	anion transmembrane transporter activity
G7047_RS17790	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G7047_RS17825	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G7047_RS17830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G7047_RS17840	COG1045	serine acetyltransferase
G7047_RS17855	COG0196	riboflavin kinase activity
G7047_RS17860	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G7047_RS17865	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G7047_RS17880	COG0183	Belongs to the thiolase family
G7047_RS17885	COG1960	acyl-CoA dehydrogenase activity
G7047_RS17895	COG2030	dehydratase
G7047_RS17900	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS17925	COG1609	Transcriptional regulator
G7047_RS17935	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
G7047_RS17940	COG1177	transmembrane transport
G7047_RS17945	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G7047_RS17950	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G7047_RS17955	COG1473	amidohydrolase
G7047_RS17960	COG1283	sodium-dependent phosphate transmembrane transporter activity
G7047_RS17970	COG0583	DNA-binding transcription factor activity
G7047_RS17975	COG2816	NAD+ diphosphatase activity
G7047_RS18000	COG0210	DNA helicase
G7047_RS18005	COG0516	GMP reductase activity
G7047_RS18040	COG0067	glutamate synthase
G7047_RS18040	COG0070	glutamate synthase
G7047_RS18040	COG0069	glutamate synthase activity
G7047_RS18085	COG4372	Transposase
G7047_RS18115	COG0232	Belongs to the dGTPase family. Type 2 subfamily
G7047_RS18120	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G7047_RS18160	COG1965	Belongs to the frataxin family
G7047_RS18170	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
G7047_RS18175	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G7047_RS18180	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G7047_RS18185	COG1333	cytochrome c biogenesis protein
G7047_RS18195	COG0218	Necessary for normal cell division and for the maintenance of normal septation
G7047_RS18200	COG1560	Kdo2-lipid A biosynthetic process
G7047_RS18210	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G7047_RS18230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
G7047_RS18235	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G7047_RS18235	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G7047_RS18240	COG1056	cytidyltransferase-related domain
G7047_RS18240	COG1051	belongs to the nudix hydrolase family
G7047_RS18255	COG0438	transferase activity, transferring glycosyl groups
G7047_RS18265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G7047_RS18270	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
G7047_RS18285	COG0463	Glycosyl transferase, family 2
G7047_RS18330	COG0419	ATPase involved in DNA repair
G7047_RS18335	COG0420	3'-5' exonuclease activity
G7047_RS18340	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G7047_RS18345	COG0459	protein refolding
G7047_RS18350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7047_RS18355	COG0166	Belongs to the GPI family
G7047_RS18360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G7047_RS18365	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G7047_RS18375	COG0737	Belongs to the 5'-nucleotidase family
G7047_RS18380	COG4608	Belongs to the ABC transporter superfamily
G7047_RS18385	COG0444	Belongs to the ABC transporter superfamily
G7047_RS18390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G7047_RS18395	COG1473	amidohydrolase
G7047_RS18410	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
G7047_RS18415	COG1765	OsmC-like protein
G7047_RS18420	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G7047_RS18425	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
G7047_RS18495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G7047_RS18520	COG1132	(ABC) transporter
G7047_RS18525	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G7047_RS18525	COG0189	ligase activity
G7047_RS18530	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G7047_RS18530	COG0189	ligase activity
G7047_RS18535	COG3045	CreA protein
G7047_RS18540	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G7047_RS18560	COG0411	ABC transporter
G7047_RS18585	COG0745	RESPONSE REGULATOR receiver
G7047_RS18590	COG0318	PFAM AMP-dependent synthetase and ligase
G7047_RS18595	COG0183	Belongs to the thiolase family
G7047_RS18610	COG0693	protein deglycase activity
G7047_RS18620	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G7047_RS18625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7047_RS18630	COG2274	protein secretion by the type I secretion system
G7047_RS18635	COG1538	Outer membrane efflux protein
G7047_RS18650	COG1522	sequence-specific DNA binding
G7047_RS18665	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G7047_RS18675	COG0583	DNA-binding transcription factor activity
G7047_RS18685	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G7047_RS18695	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G7047_RS18700	COG0316	Belongs to the HesB IscA family
G7047_RS18705	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G7047_RS18710	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G7047_RS18720	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
G7047_RS18725	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G7047_RS18730	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
G7047_RS18740	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G7047_RS18745	COG0745	RESPONSE REGULATOR receiver
G7047_RS18750	COG2205	protein histidine kinase activity
G7047_RS18755	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
G7047_RS18765	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
G7047_RS18775	COG2814	Major facilitator Superfamily
G7047_RS18785	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G7047_RS18800	COG2076	Multidrug Resistance protein
G7047_RS18820	COG1126	abc transporter atp-binding protein
G7047_RS18825	COG0765	amino acid transport
G7047_RS18830	COG0765	amino acid transport
G7047_RS18845	COG0583	DNA-binding transcription factor activity
G7047_RS18860	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G7047_RS18865	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G7047_RS18885	COG2369	cell adhesion
G7047_RS18890	COG4383	Mu-like prophage protein gp29
G7047_RS18895	COG4373	Mu-like prophage FluMu protein gp28
G7047_RS18905	COG0640	Transcriptional regulator
G7047_RS19015	COG2974	May be involved in recombination
G7047_RS19050	COG4397	Mu-like prophage major head subunit gpT
G7047_RS19125	COG0022	dehydrogenase e1 component
G7047_RS19130	COG5265	(ABC) transporter
G7047_RS19135	COG1607	acyl-coa hydrolase
G7047_RS19145	COG2050	protein possibly involved in aromatic compounds catabolism
G7047_RS19150	COG1024	Enoyl-CoA hydratase
G7047_RS19160	COG0183	Belongs to the thiolase family
G7047_RS19165	COG1250	3-hydroxyacyl-CoA dehydrogenase
G7047_RS19165	COG1024	Enoyl-CoA hydratase
G7047_RS19175	COG1960	acyl-CoA dehydrogenase activity
G7047_RS19430	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G7047_RS19445	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G7047_RS19455	COG2226	methyltransferase
G7047_RS19475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G7047_RS19490	COG1450	Type ii and iii secretion system protein
G7047_RS19520	COG2165	general secretion pathway protein
G7047_RS19530	COG2165	general secretion pathway protein
G7047_RS19535	COG1459	type II secretion system
G7047_RS19540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G7047_RS19580	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
G7047_RS19585	COG1652	LysM domain
G7047_RS19605	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
G7047_RS19610	COG0751	glycine-tRNA ligase activity
G7047_RS19615	COG0752	glycyl-tRNA synthetase alpha subunit
G7047_RS19625	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G7047_RS19630	COG0815	Transfers the fatty acyl group on membrane lipoproteins
G7047_RS19635	COG4535	Mg2 and Co2 transporter CorC
G7047_RS19645	COG1522	sequence-specific DNA binding
G7047_RS19660	COG3186	Phenylalanine-4-hydroxylase
G7047_RS19670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G7047_RS19675	COG4774	siderophore transport
G7047_RS19680	COG3128	pkhd-type hydroxylase
G7047_RS19695	COG0739	heme binding
G7047_RS19695	COG0741	lytic transglycosylase activity
G7047_RS19695	COG1196	nuclear chromosome segregation
G7047_RS19700	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G7047_RS19705	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G7047_RS19715	COG0617	tRNA 3'-terminal CCA addition
G7047_RS19730	COG1877	trehalose-phosphatase activity
G7047_RS19735	COG3387	PFAM Glycoside hydrolase 15-related
G7047_RS19740	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
G7047_RS19765	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS19780	COG0037	tRNA processing
G7047_RS19815	COG3552	Protein containing von Willebrand factor type A (VWA) domain
G7047_RS19830	COG0326	Molecular chaperone. Has ATPase activity
G7047_RS19835	COG0714	Associated with various cellular activities
G7047_RS19870	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G7047_RS19880	COG2255	four-way junction helicase activity
G7047_RS19885	COG1802	Transcriptional regulator
G7047_RS19900	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
G7047_RS19905	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G7047_RS19910	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
G7047_RS19915	COG4770	biotin carboxylase activity
G7047_RS19930	COG0443	Heat shock 70 kDa protein
G7047_RS19960	COG0583	DNA-binding transcription factor activity
G7047_RS19965	COG0730	response to heat
G7047_RS19970	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G7047_RS19975	COG1702	phosphate starvation-inducible protein PhoH
G7047_RS19980	COG0632	four-way junction helicase activity
G7047_RS20000	COG1490	D-aminoacyl-tRNA deacylase activity
G7047_RS20005	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
G7047_RS20010	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G7047_RS20020	COG1250	3-hydroxyacyl-CoA dehydrogenase
G7047_RS20040	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G7047_RS20060	COG0326	Molecular chaperone. Has ATPase activity
G7047_RS20085	COG1187	pseudouridine synthase activity
G7047_RS20090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G7047_RS20100	COG3409	Peptidoglycan-binding domain 1 protein
G7047_RS20100	COG3267	Type II secretory pathway component ExeA
G7047_RS20105	COG1022	Amp-dependent synthetase and ligase
G7047_RS20150	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G7047_RS20160	COG2818	Glycosylase
G7047_RS20180	COG1473	amidohydrolase
G7047_RS20190	COG0243	molybdopterin cofactor binding
G7047_RS20235	COG3945	hemerythrin HHE cation binding domain
G7047_RS20250	COG0288	reversible hydration of carbon dioxide
G7047_RS20255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G7047_RS20260	COG2181	nitrate reductase activity
G7047_RS20265	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
G7047_RS20270	COG1140	nitrate reductase beta subunit
G7047_RS20275	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
G7047_RS20280	COG2223	nitrite transmembrane transporter activity
G7047_RS20290	COG2197	response regulator
G7047_RS20295	COG3850	Histidine kinase
G7047_RS20320	COG0583	DNA-binding transcription factor activity
G7047_RS20325	COG0277	FAD linked oxidase domain protein
G7047_RS20340	COG2733	membrane
G7047_RS20345	COG0545	Peptidyl-prolyl cis-trans isomerase
G7047_RS20370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G7047_RS20380	COG2084	Dehydrogenase
G7047_RS20385	COG2823	Periplasmic or secreted lipoprotein
G7047_RS20390	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
G7047_RS20395	COG0792	nuclease activity
G7047_RS20415	COG0318	PFAM AMP-dependent synthetase and ligase
G7047_RS20430	COG0411	ABC transporter
G7047_RS20435	COG0559	Belongs to the binding-protein-dependent transport system permease family
G7047_RS20445	COG0443	Heat shock 70 kDa protein
G7047_RS20455	COG0203	ribosomal protein L17
G7047_RS20460	COG0202	RNA polymerase activity
G7047_RS20465	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G7047_RS20470	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G7047_RS20475	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G7047_RS20480	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G7047_RS20485	COG0201	protein transport
G7047_RS20490	COG0200	Binds to the 23S rRNA
G7047_RS20495	COG1841	ribosomal large subunit assembly
G7047_RS20500	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G7047_RS20505	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G7047_RS20510	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G7047_RS20515	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G7047_RS20520	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G7047_RS20525	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G7047_RS20530	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
G7047_RS20535	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G7047_RS20555	COG0395	ABC-type sugar transport system, permease component
G7047_RS20565	COG3842	ATPase activity
G7047_RS20580	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G7047_RS20585	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G7047_RS20615	COG3384	dioxygenase
G7047_RS20620	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G7047_RS20630	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G7047_RS20640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G7047_RS20645	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS20655	COG4604	ABC transporter, ATP-binding protein
G7047_RS20660	COG4605	iron ion homeostasis
G7047_RS20665	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G7047_RS20670	COG4607	ABC-type enterochelin transport system periplasmic component
G7047_RS20695	COG0583	DNA-binding transcription factor activity
G7047_RS20700	COG4589	Belongs to the CDS family
G7047_RS20715	COG0671	phosphoesterase, PA-phosphatase related
G7047_RS20715	COG2453	phosphatase
G7047_RS20720	COG2267	carboxylic ester hydrolase activity
G7047_RS20725	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G7047_RS20730	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G7047_RS20745	COG0134	indole-3-glycerol-phosphate synthase activity
G7047_RS20750	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G7047_RS20755	COG0512	Glutamine amidotransferase of anthranilate synthase
G7047_RS20775	COG0840	transmembrane signaling receptor activity
G7047_RS20780	COG0546	phosphoglycolate phosphatase activity
G7047_RS20795	COG2967	ApaG domain
G7047_RS20810	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
G7047_RS20830	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G7047_RS20835	COG1546	Belongs to the CinA family
G7047_RS20840	COG1869	D-ribose catabolic process
G7047_RS20845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G7047_RS20855	COG1172	Belongs to the binding-protein-dependent transport system permease family
G7047_RS20860	COG1129	ABC transporter
G7047_RS20870	COG0653	protein targeting
G7047_RS20875	COG0069	glutamate synthase activity
G7047_RS20895	COG1960	acyl-CoA dehydrogenase activity
G7047_RS20905	COG0183	Belongs to the thiolase family
G7047_RS20920	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS20935	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G7047_RS20955	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G7047_RS20955	COG0116	Belongs to the methyltransferase superfamily
G7047_RS20960	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G7047_RS20980	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
G7047_RS20985	COG1137	ATPase activity
G7047_RS20990	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
G7047_RS20995	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G7047_RS21005	COG0018	arginyl-trna synthetase
G7047_RS21035	COG5002	protein histidine kinase activity
G7047_RS21040	COG0745	RESPONSE REGULATOR receiver
G7047_RS21050	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G7047_RS21055	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
G7047_RS21065	COG1215	transferase activity, transferring glycosyl groups
G7047_RS21085	COG1696	Membrane protein involved in D-alanine export
G7047_RS21090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G7047_RS21095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G7047_RS21105	COG1960	acyl-CoA dehydrogenase activity
G7047_RS21125	COG1942	4-Oxalocrotonate Tautomerase
G7047_RS21135	COG0121	glutamine amidotransferase
G7047_RS21245	COG1704	LemA family
G7047_RS21260	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G7047_RS21265	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G7047_RS21270	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G7047_RS21275	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G7047_RS21280	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G7047_RS21285	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G7047_RS21295	COG0356	it plays a direct role in the translocation of protons across the membrane
G7047_RS21305	COG2921	Belongs to the UPF0250 family
G7047_RS21310	COG0321	lipoyl(octanoyl) transferase activity
G7047_RS21315	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G7047_RS21320	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G7047_RS21330	COG3604	Transcriptional regulator
G7047_RS21335	COG1017	nitric oxide dioxygenase activity
G7047_RS21335	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G7047_RS21340	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G7047_RS21345	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G7047_RS21360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G7047_RS21365	COG3909	cytochrome
G7047_RS21375	COG0456	acetyltransferase
G7047_RS21380	COG1683	Conserved Protein
G7047_RS21385	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS21390	COG0678	peroxiredoxin activity
G7047_RS21395	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G7047_RS21400	COG0255	Belongs to the universal ribosomal protein uL29 family
G7047_RS21405	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G7047_RS21410	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G7047_RS21415	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G7047_RS21420	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G7047_RS21425	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G7047_RS21430	COG0089	rRNA binding
G7047_RS21435	COG0088	Forms part of the polypeptide exit tunnel
G7047_RS21440	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G7047_RS21445	COG0051	transcription antitermination factor activity, RNA binding
G7047_RS21450	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G7047_RS21455	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G7047_RS21460	COG0049	tRNA binding
G7047_RS21465	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G7047_RS21475	COG1686	Belongs to the peptidase S11 family
G7047_RS21480	COG2945	thiolester hydrolase activity
G7047_RS21500	COG0501	Belongs to the peptidase M48B family
G7047_RS21510	COG0598	Magnesium transport protein CorA
G7047_RS21530	COG0412	Dienelactone hydrolase
G7047_RS21535	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS21540	COG2095	MarC family integral membrane protein
G7047_RS21545	COG0745	RESPONSE REGULATOR receiver
G7047_RS21550	COG2205	protein histidine kinase activity
G7047_RS21555	COG4452	Inner membrane protein CreD
G7047_RS21570	COG0024	Methionine aminopeptidase
G7047_RS21595	COG1127	ABC transporter
G7047_RS21600	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G7047_RS21610	COG1802	Transcriptional regulator
G7047_RS21635	COG0277	FAD linked oxidase domain protein
G7047_RS21635	COG0247	lactate metabolic process
G7047_RS21645	COG0477	Major facilitator Superfamily
G7047_RS21650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G7047_RS21680	COG0004	ammonium transporteR
G7047_RS21695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7047_RS21700	COG0765	amino acid transport
G7047_RS21715	COG0768	penicillin binding
G7047_RS21730	COG1077	Cell shape determining protein MreB Mrl
G7047_RS21735	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G7047_RS21740	COG0154	amidase activity
G7047_RS21745	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G7047_RS21775	COG5001	Diguanylate cyclase
G7047_RS21775	COG3300	MHYT domain
G7047_RS21785	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G7047_RS21790	COG0708	Exodeoxyribonuclease III
G7047_RS21795	COG2819	hydrolase of the alpha beta superfamily
G7047_RS21805	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS21820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G7047_RS21845	COG1846	Transcriptional regulator
G7047_RS21850	COG1960	acyl-CoA dehydrogenase activity
G7047_RS21865	COG1024	Enoyl-CoA hydratase
G7047_RS21870	COG1012	belongs to the aldehyde dehydrogenase family
G7047_RS21880	COG4372	Transposase
G7047_RS21895	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G7047_RS21920	COG0018	arginyl-trna synthetase
G7047_RS21925	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G7047_RS21935	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G7047_RS21940	COG0251	oxidation-reduction process
G7047_RS21960	COG0625	glutathione transferase activity
G7047_RS21965	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G7047_RS21975	COG2207	Transcriptional regulator
G7047_RS21985	COG0189	ligase activity
G7047_RS22000	COG0471	metal ion transport
G7047_RS22015	COG1573	uracil-dna glycosylase
G7047_RS22040	COG4372	Transposase
G7047_RS22060	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G7047_RS22085	COG2944	sequence-specific DNA binding
G7047_RS22095	COG1794	racemase activity, acting on amino acids and derivatives
G7047_RS22120	COG0583	DNA-binding transcription factor activity
G7047_RS22130	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G7047_RS22155	COG4372	Transposase
G7047_RS22185	COG4372	Transposase
G7047_RS22210	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G7047_RS22215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G7047_RS22225	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G7047_RS22230	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G7047_RS22235	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G7047_RS22250	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G7047_RS22255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G7047_RS22265	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS22270	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS22280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G7047_RS22340	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS22345	COG1802	Transcriptional regulator
G7047_RS22355	COG0559	Belongs to the binding-protein-dependent transport system permease family
G7047_RS22360	COG4177	L-phenylalanine transmembrane transporter activity
G7047_RS22380	COG1744	ABC transporter substrate-binding protein PnrA-like
G7047_RS22400	COG0402	S-adenosylhomocysteine deaminase activity
G7047_RS22430	COG4290	ribonuclease
G7047_RS22445	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G7047_RS22450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G7047_RS22455	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
G7047_RS22465	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G7047_RS22480	COG1196	nuclear chromosome segregation
G7047_RS22495	COG2267	carboxylic ester hydrolase activity
G7047_RS22505	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G7047_RS22510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G7047_RS22515	COG2119	membrane
G7047_RS22520	COG0724	RNA recognition motif
G7047_RS22525	COG0724	RNA recognition motif
G7047_RS22555	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G7047_RS22585	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS22595	COG3622	Belongs to the hyi family
G7047_RS22600	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
G7047_RS22640	COG3451	type IV secretory pathway VirB4
G7047_RS22650	COG3838	Conjugal transfer protein Trbc
G7047_RS22655	COG4962	Type ii secretion system protein e
G7047_RS22675	COG0583	DNA-binding transcription factor activity
G7047_RS22690	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
G7047_RS22695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS22700	COG0583	DNA-binding transcription factor activity
G7047_RS22720	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
G7047_RS22740	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS22750	COG0129	dihydroxy-acid dehydratase activity
G7047_RS22770	COG1881	PFAM PEBP family protein
G7047_RS22780	COG4959	Type IV secretory pathway protease TraF
G7047_RS22795	COG1192	Involved in chromosome partitioning
G7047_RS22835	COG5489	Protein of unknown function (DUF736)
G7047_RS22870	COG1475	DNA binding
G7047_RS22895	COG4804	nuclease activity
G7047_RS22910	COG0706	membrane insertase activity
G7047_RS22915	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G7047_RS22920	COG0594	ribonuclease P activity
G7047_RS22925	COG0230	Belongs to the bacterial ribosomal protein bL34 family
G7047_RS22930	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G7047_RS22945	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G7047_RS22950	COG0659	secondary active sulfate transmembrane transporter activity
G7047_RS22955	COG0829	nickel cation binding
G7047_RS22975	COG0559	Belongs to the binding-protein-dependent transport system permease family
G7047_RS22985	COG0831	urea catabolic process
G7047_RS22995	COG0832	Belongs to the urease beta subunit family
G7047_RS23000	COG0804	urea catabolic process
G7047_RS23010	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
G7047_RS23015	COG0830	nickel cation binding
G7047_RS23025	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
G7047_RS23030	COG1414	Transcriptional regulator
G7047_RS23035	COG1414	Transcriptional regulator
G7047_RS23055	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS23060	COG1024	Enoyl-CoA hydratase
G7047_RS23065	COG1024	Enoyl-CoA hydratase
G7047_RS23070	COG1024	Enoyl-CoA hydratase
G7047_RS23095	COG1024	Enoyl-CoA hydratase
G7047_RS23110	COG0028	Belongs to the TPP enzyme family
G7047_RS23115	COG0430	RNA-3'-phosphate cyclase activity
G7047_RS23125	COG3541	Predicted nucleotidyltransferase
G7047_RS23130	COG1690	Belongs to the RtcB family
G7047_RS23140	COG4650	regulator
G7047_RS23145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7047_RS23150	COG0765	amino acid transport
G7047_RS23155	COG0765	amino acid transport
G7047_RS23185	COG2271	Major facilitator Superfamily
G7047_RS23200	COG5002	protein histidine kinase activity
G7047_RS23225	COG1764	response to oxidative stress
G7047_RS23235	COG0243	molybdopterin cofactor binding
G7047_RS23240	COG2146	nitrite reductase [NAD(P)H] activity
G7047_RS23245	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G7047_RS23250	COG1116	anion transmembrane transporter activity
G7047_RS23255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G7047_RS23260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G7047_RS23265	COG3707	response regulator
G7047_RS23275	COG0210	DNA helicase
G7047_RS23280	COG1199	ATP-dependent helicase activity
G7047_RS23310	COG1794	racemase activity, acting on amino acids and derivatives
G7047_RS23320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G7047_RS23335	COG2096	Adenosyltransferase
G7047_RS23345	COG0277	FAD linked oxidase domain protein
G7047_RS23395	COG5507	3-demethylubiquinone-9 3-methyltransferase
G7047_RS23405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G7047_RS23430	COG1192	Involved in chromosome partitioning
G7047_RS23440	COG0357	Ribosomal RNA small subunit methyltransferase G
G7047_RS23445	COG0445	tRNA wobble uridine modification
G7047_RS23450	COG0625	glutathione transferase activity
G7047_RS23460	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS23465	COG0179	Fumarylacetoacetate (FAA) hydrolase
G7047_RS23485	COG0431	NADPH-dependent FMN reductase
G7047_RS23490	COG1902	pentaerythritol trinitrate reductase activity
G7047_RS23520	COG2217	Heavy metal translocating P-type atpase
G7047_RS23525	COG4772	TonB-dependent receptor
G7047_RS23535	COG3284	Transcriptional regulator
G7047_RS23570	COG0446	pyridine nucleotide-disulphide oxidoreductase
G7047_RS23600	COG0789	Transcriptional regulator
G7047_RS23605	COG0583	DNA-binding transcription factor activity
G7047_RS23615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G7047_RS23625	COG2715	membrane protein required for spore maturation
G7047_RS23635	COG0583	DNA-binding transcription factor activity
G7047_RS23650	COG2205	protein histidine kinase activity
G7047_RS23650	COG0784	Response regulator, receiver
G7047_RS23655	COG1301	dicarboxylic acid transport
G7047_RS23665	COG2974	May be involved in recombination
G7047_RS23695	COG1024	Enoyl-CoA hydratase
G7047_RS23710	COG1960	acyl-CoA dehydrogenase activity
G7047_RS23715	COG1960	acyl-CoA dehydrogenase activity
G7047_RS23720	COG1737	Transcriptional regulator
G7047_RS23725	COG0477	Major facilitator Superfamily
G7047_RS23740	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS23745	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G7047_RS23750	COG3209	COG3209 Rhs family protein
G7047_RS23755	COG0791	NLP P60 protein
G7047_RS23760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G7047_RS23765	COG2050	protein possibly involved in aromatic compounds catabolism
G7047_RS23780	COG2233	PERMEase
G7047_RS23790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS23835	COG0583	DNA-binding transcription factor activity
G7047_RS23845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS23850	COG1960	acyl-CoA dehydrogenase activity
G7047_RS23855	COG1960	acyl-CoA dehydrogenase activity
G7047_RS23865	COG1183	phosphatidylcholine synthase activity
G7047_RS23875	COG0850	regulation of cytokinetic process
G7047_RS23885	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
G7047_RS23890	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G7047_RS23895	COG1073	alpha beta
G7047_RS23930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G7047_RS23935	COG0583	DNA-binding transcription factor activity
G7047_RS23970	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
G7047_RS23980	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G7047_RS23985	COG1960	acyl-CoA dehydrogenase activity
G7047_RS23995	COG2205	protein histidine kinase activity
G7047_RS24000	COG0745	RESPONSE REGULATOR receiver
G7047_RS24015	COG0577	efflux transmembrane transporter activity
G7047_RS24015	COG1136	(ABC) transporter
G7047_RS24050	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G7047_RS24085	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS24090	COG0583	DNA-binding transcription factor activity
G7047_RS24125	COG1760	l-serine dehydratase
G7047_RS24130	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G7047_RS24130	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G7047_RS24160	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
G7047_RS24165	COG1960	acyl-CoA dehydrogenase activity
G7047_RS24190	COG0477	Major facilitator Superfamily
G7047_RS24195	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
G7047_RS24200	COG1414	Transcriptional regulator
G7047_RS24220	COG3949	Membrane
G7047_RS24230	COG2223	nitrite transmembrane transporter activity
G7047_RS24235	COG2207	Transcriptional regulator
G7047_RS24290	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G7047_RS24295	COG2326	polyphosphate kinase activity
G7047_RS24300	COG2814	Major facilitator Superfamily
G7047_RS24325	COG0402	S-adenosylhomocysteine deaminase activity
G7047_RS24330	COG0583	DNA-binding transcription factor activity
G7047_RS24340	COG0583	DNA-binding transcription factor activity
G7047_RS24360	COG0583	DNA-binding transcription factor activity
G7047_RS24375	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS24395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS24400	COG2072	flavoprotein involved in K transport
G7047_RS24405	COG0583	DNA-binding transcription factor activity
G7047_RS24415	COG1410	methionine synthase
G7047_RS24415	COG0646	methionine synthase
G7047_RS24420	COG0584	glycerophosphoryl diester phosphodiesterase
G7047_RS24430	COG0133	tryptophan synthase activity
G7047_RS24435	COG2186	Transcriptional regulator
G7047_RS24440	COG1301	dicarboxylic acid transport
G7047_RS24465	COG0457	Tetratricopeptide repeat
G7047_RS24475	COG1305	Transglutaminase-like
G7047_RS24480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G7047_RS24485	COG2197	response regulator
G7047_RS24490	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G7047_RS24510	COG1024	Enoyl-CoA hydratase
G7047_RS24510	COG1250	3-hydroxyacyl-CoA dehydrogenase
G7047_RS24515	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G7047_RS24520	COG0439	Biotin carboxylase
G7047_RS24525	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G7047_RS24535	COG1414	Transcriptional regulator
G7047_RS24560	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
G7047_RS24580	COG0307	riboflavin synthase, alpha
G7047_RS24595	COG0494	nUDIX hydrolase
G7047_RS24625	COG0747	negative chemotaxis
G7047_RS24630	COG4608	Belongs to the ABC transporter superfamily
G7047_RS24635	COG0444	Belongs to the ABC transporter superfamily
G7047_RS24640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G7047_RS24645	COG0601	transmembrane transport
G7047_RS24650	COG2072	flavoprotein involved in K transport
G7047_RS24685	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G7047_RS24685	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G7047_RS24695	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS24715	COG0583	DNA-binding transcription factor activity
G7047_RS24720	COG1380	Effector of murein hydrolase LrgA
G7047_RS24725	COG1346	cytolysis
G7047_RS24735	COG4585	Histidine kinase
G7047_RS24745	COG0583	DNA-binding transcription factor activity
G7047_RS24760	COG1012	belongs to the aldehyde dehydrogenase family
G7047_RS24775	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G7047_RS24800	COG0318	PFAM AMP-dependent synthetase and ligase
G7047_RS24810	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G7047_RS24815	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS24820	COG1846	Transcriptional regulator
G7047_RS24830	COG0411	ABC transporter
G7047_RS24845	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS24850	COG0606	chelatase, subunit chli
G7047_RS24865	COG0004	ammonium transporteR
G7047_RS24880	COG0277	FAD linked oxidase domain protein
G7047_RS24885	COG0247	lactate metabolic process
G7047_RS24910	COG0386	Belongs to the glutathione peroxidase family
G7047_RS24915	COG0583	DNA-binding transcription factor activity
G7047_RS24920	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G7047_RS24940	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G7047_RS24950	COG1858	cytochrome C peroxidase
G7047_RS24955	COG0625	glutathione transferase activity
G7047_RS24980	COG3971	2-oxopent-4-enoate hydratase activity
G7047_RS25000	COG1012	belongs to the aldehyde dehydrogenase family
G7047_RS25010	COG0179	Fumarylacetoacetate (FAA) hydrolase
G7047_RS25015	COG1846	Transcriptional regulator
G7047_RS25075	COG1216	Glycosyl transferase, family 2
G7047_RS25100	COG0477	Major facilitator Superfamily
G7047_RS25120	COG0662	Cupin 2, conserved barrel domain protein
G7047_RS25120	COG2207	Transcriptional regulator
G7047_RS25125	COG0697	spore germination
G7047_RS25135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G7047_RS25150	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS25155	COG4628	conserved protein (DUF2132)
G7047_RS25185	COG0583	DNA-binding transcription factor activity
G7047_RS25205	COG0443	Heat shock 70 kDa protein
G7047_RS25220	COG0482	sulfurtransferase activity
G7047_RS25225	COG1620	l-lactate permease
G7047_RS25235	COG2084	Dehydrogenase
G7047_RS25240	COG3622	Belongs to the hyi family
G7047_RS25245	COG3960	tartronate-semialdehyde synthase activity
G7047_RS25250	COG0583	DNA-binding transcription factor activity
G7047_RS25255	COG1716	ATPase activity
G7047_RS25255	COG5001	Diguanylate cyclase
G7047_RS25300	COG2948	multi-organism process
G7047_RS25315	COG3846	protein secretion by the type IV secretion system
G7047_RS25330	COG3451	type IV secretory pathway VirB4
G7047_RS25340	COG3838	Conjugal transfer protein Trbc
G7047_RS25345	COG4962	Type ii secretion system protein e
G7047_RS25365	COG0583	DNA-binding transcription factor activity
G7047_RS25370	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
G7047_RS25375	COG2194	sulfuric ester hydrolase activity
G7047_RS25405	COG3038	cytochrome b561
G7047_RS25415	COG0642	Histidine kinase
G7047_RS25455	COG1192	Involved in chromosome partitioning
G7047_RS25500	COG5489	Protein of unknown function (DUF736)
G7047_RS25525	COG1475	DNA binding
G7047_RS25545	COG3039	Transposase
G7047_RS25550	COG2217	Heavy metal translocating P-type atpase
G7047_RS25570	COG2132	Multicopper oxidase
G7047_RS25580	COG2205	protein histidine kinase activity
G7047_RS25595	COG3039	Transposase
G7047_RS25690	COG4372	Transposase
G7047_RS25715	COG1111	helicase
G7047_RS25715	COG1205	dead DEAH box helicase
G7047_RS25745	COG4974	Belongs to the 'phage' integrase family
G7047_RS25750	COG0629	single-stranded DNA binding
G7047_RS25755	COG2814	Major facilitator Superfamily
G7047_RS25760	COG2194	sulfuric ester hydrolase activity
G7047_RS25780	COG1012	belongs to the aldehyde dehydrogenase family
G7047_RS25800	COG0583	DNA-binding transcription factor activity
G7047_RS25805	COG0284	orotidine-5'-phosphate decarboxylase activity
G7047_RS25825	COG0126	phosphoglycerate kinase activity
G7047_RS25840	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G7047_RS25850	COG0242	peptide deformylase activity
G7047_RS25855	COG1652	LysM domain
G7047_RS25860	COG0758	DNA mediated transformation
G7047_RS25865	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G7047_RS25870	COG0045	succinate-CoA ligase (ADP-forming) activity
G7047_RS25875	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G7047_RS25880	COG0861	Integral membrane protein TerC family
G7047_RS25885	COG0861	Integral membrane protein TerC family
G7047_RS25900	COG4969	Belongs to the N-Me-Phe pilin family
G7047_RS25910	COG0315	cyclic pyranopterin monophosphate synthase activity
G7047_RS25915	COG4783	chaperone-mediated protein folding
G7047_RS25920	COG1950	PFAM Membrane protein of
G7047_RS25930	COG0861	Integral membrane protein TerC family
G7047_RS25960	COG0625	glutathione transferase activity
G7047_RS25980	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G7047_RS26000	COG4566	intracellular signal transduction
G7047_RS26015	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
G7047_RS26035	COG1522	sequence-specific DNA binding
G7047_RS26045	COG1862	Preprotein translocase
G7047_RS26050	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G7047_RS26055	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G7047_RS26070	COG2137	regulation of response to DNA damage stimulus
G7047_RS26075	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G7047_RS26085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G7047_RS26095	COG1012	belongs to the aldehyde dehydrogenase family
G7047_RS26105	COG1802	Transcriptional regulator
G7047_RS26110	COG1840	ABC-type Fe3 transport system, periplasmic component
G7047_RS26115	COG3842	ATPase activity
G7047_RS26135	COG0642	Histidine kinase
G7047_RS26145	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS26155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS26165	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
G7047_RS26170	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS26175	COG2084	Dehydrogenase
G7047_RS26190	COG0411	ABC transporter
G7047_RS26200	COG3386	PFAM SMP-30 Gluconolaconase
G7047_RS26225	COG1335	isochorismatase
G7047_RS26250	COG1802	Transcriptional regulator
G7047_RS26280	COG0644	oxidoreductase
G7047_RS26295	COG1566	PFAM secretion protein HlyD family protein
G7047_RS26325	COG2084	Dehydrogenase
G7047_RS26330	COG1012	belongs to the aldehyde dehydrogenase family
G7047_RS26365	COG0457	Tetratricopeptide repeat
G7047_RS26365	COG0463	Glycosyl transferase, family 2
G7047_RS26415	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS26425	COG0583	DNA-binding transcription factor activity
G7047_RS26440	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS26455	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G7047_RS26480	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G7047_RS26485	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G7047_RS26500	COG0006	proline dipeptidase activity
G7047_RS26545	COG2159	amidohydrolase
G7047_RS26550	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS26555	COG0179	Fumarylacetoacetate (FAA) hydrolase
G7047_RS26570	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS26580	COG1690	Belongs to the RtcB family
G7047_RS26585	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
G7047_RS26590	COG0469	pyruvate kinase activity
G7047_RS26625	COG0318	PFAM AMP-dependent synthetase and ligase
G7047_RS26630	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G7047_RS26635	COG0598	Magnesium transport protein CorA
G7047_RS26650	COG1214	PFAM Peptidase M22, glycoprotease
G7047_RS26675	COG0009	L-threonylcarbamoyladenylate synthase
G7047_RS26680	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G7047_RS26685	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G7047_RS26690	COG3118	belongs to the thioredoxin family
G7047_RS26700	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G7047_RS26705	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G7047_RS26715	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
G7047_RS26720	COG0735	belongs to the Fur family
G7047_RS26725	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G7047_RS26730	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G7047_RS26755	COG0668	transmembrane transport
G7047_RS26760	COG0495	leucyl-tRNA aminoacylation
G7047_RS26780	COG5285	phytanoyl-CoA dioxygenase
G7047_RS26785	COG0662	Cupin 2, conserved barrel domain protein
G7047_RS26790	COG4953	penicillin-binding protein 1C
G7047_RS26795	COG2373	Large extracellular alpha-helical protein
G7047_RS26800	COG3639	organic phosphonate transmembrane transporter activity
G7047_RS26805	COG3639	organic phosphonate transmembrane transporter activity
G7047_RS26810	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
G7047_RS26835	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G7047_RS26840	COG0569	domain protein
G7047_RS26845	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G7047_RS26860	COG3158	transport of potassium into the cell
G7047_RS26865	COG3135	benzoate transporter
G7047_RS26870	COG0189	ligase activity
G7047_RS26920	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G7047_RS26940	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G7047_RS26945	COG0081	regulation of translation
G7047_RS26950	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G7047_RS26955	COG0222	ribosome binding
G7047_RS26960	COG0085	RNA polymerase activity
G7047_RS26965	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G7047_RS26985	COG5000	phosphorelay sensor kinase activity
G7047_RS26990	COG2204	response regulator
G7047_RS27000	COG1595	DNA-templated transcription, initiation
G7047_RS27020	COG2365	Tyrosine phosphatase family
G7047_RS27055	COG0204	Acyl-transferase
G7047_RS27055	COG0318	PFAM AMP-dependent synthetase and ligase
G7047_RS27080	COG5002	protein histidine kinase activity
G7047_RS27080	COG5001	Diguanylate cyclase
G7047_RS27080	COG3447	MASE1 domain protein
G7047_RS27085	COG0343	queuine tRNA-ribosyltransferase activity
G7047_RS27110	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS27115	COG1024	Enoyl-CoA hydratase
G7047_RS27120	COG1960	acyl-CoA dehydrogenase activity
G7047_RS27150	COG0210	DNA helicase
G7047_RS27175	COG0679	Auxin Efflux Carrier
G7047_RS27195	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G7047_RS27200	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G7047_RS27205	COG3237	CsbD-like
G7047_RS27220	COG1832	CoA-binding protein
G7047_RS27230	COG3706	GGDEF domain
G7047_RS27240	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G7047_RS27255	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS27260	COG0534	Mate efflux family protein
G7047_RS27295	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G7047_RS27305	COG0384	phenazine biosynthesis protein PhzF
G7047_RS27310	COG0625	glutathione transferase activity
G7047_RS27315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G7047_RS27325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G7047_RS27335	COG2201	protein-glutamate methylesterase activity
G7047_RS27340	COG2198	Histidine kinase
G7047_RS27340	COG0643	Histidine kinase
G7047_RS27345	COG0835	chemotaxis
G7047_RS27350	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G7047_RS27355	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
G7047_RS27360	COG2201	protein-glutamate methylesterase activity
G7047_RS27390	COG0789	Transcriptional regulator
G7047_RS27395	COG1960	acyl-CoA dehydrogenase activity
G7047_RS27400	COG0288	reversible hydration of carbon dioxide
G7047_RS27405	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
G7047_RS27410	COG0183	Belongs to the thiolase family
G7047_RS27430	COG1960	acyl-CoA dehydrogenase activity
G7047_RS27465	COG0656	L-ascorbic acid biosynthetic process
G7047_RS27470	COG3012	SEC-C Motif Domain Protein
G7047_RS27475	COG2198	Histidine kinase
G7047_RS27475	COG0784	Response regulator, receiver
G7047_RS27475	COG5002	protein histidine kinase activity
G7047_RS27490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G7047_RS27500	COG0318	PFAM AMP-dependent synthetase and ligase
G7047_RS27510	COG0025	NhaP-type Na H and K H
G7047_RS27515	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G7047_RS27530	COG4770	biotin carboxylase activity
G7047_RS27535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G7047_RS27605	COG0683	leucine binding
G7047_RS27610	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G7047_RS27615	COG0418	dihydroorotase activity
G7047_RS27630	COG0501	Belongs to the peptidase M48B family
G7047_RS27650	COG2368	4-hydroxyphenylacetate
G7047_RS27670	COG0411	ABC transporter
G7047_RS27675	COG0410	ABC transporter
G7047_RS27680	COG2072	flavoprotein involved in K transport
G7047_RS27700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G7047_RS27705	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS27715	COG0318	PFAM AMP-dependent synthetase and ligase
G7047_RS27720	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
G7047_RS27725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G7047_RS27740	COG0697	spore germination
G7047_RS27745	COG2207	Transcriptional regulator
G7047_RS27770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G7047_RS27775	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G7047_RS27785	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
G7047_RS27790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G7047_RS27800	COG2020	methyltransferase activity
G7047_RS27805	COG0583	DNA-binding transcription factor activity
G7047_RS27840	COG0667	Aldo Keto reductase
G7047_RS27845	COG1414	Transcriptional regulator
G7047_RS27855	COG0523	cobalamin synthesis protein
G7047_RS27870	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
G7047_RS27875	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
G7047_RS27880	COG2001	Belongs to the MraZ family
G7047_RS27885	COG0275	rRNA processing
G7047_RS27900	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G7047_RS27905	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G7047_RS27910	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G7047_RS27915	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G7047_RS27920	COG0772	Belongs to the SEDS family
G7047_RS27925	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G7047_RS27930	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G7047_RS27935	COG1181	Belongs to the D-alanine--D-alanine ligase family
G7047_RS27940	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G7047_RS27955	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
G7047_RS27975	COG0175	sulfate reduction
G7047_RS28005	COG1028	Short-chain dehydrogenase reductase Sdr
G7047_RS28015	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
G7047_RS28025	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
G7047_RS28030	COG1414	Transcriptional regulator
G7047_RS28035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G7047_RS28040	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G7047_RS28060	COG3150	esterase
G7047_RS28065	COG0772	Belongs to the SEDS family
G7047_RS28070	COG0312	modulator of DNA gyrase
G7047_RS28075	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G7047_RS28085	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G7047_RS28095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G7047_RS28100	COG0511	ligase activity, forming carbon-carbon bonds
G7047_RS28105	COG0439	Biotin carboxylase
G7047_RS28110	COG2264	protein methyltransferase activity
G7047_RS28120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G7047_RS28140	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G7047_RS28170	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G7047_RS28175	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G7047_RS28180	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G7047_RS28190	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G7047_RS28220	COG1024	Enoyl-CoA hydratase
G7047_RS28235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G7047_RS28255	COG0732	type I restriction modification DNA specificity domain
G7047_RS28260	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
G7047_RS28280	COG0012	GTP binding
G7047_RS28305	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS28315	COG1238	metal cluster binding
G7047_RS28325	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
G7047_RS28330	COG0138	bifunctional purine biosynthesis protein purh
G7047_RS28335	COG4654	Cytochrome c, class I
G7047_RS28345	COG4774	siderophore transport
G7047_RS28355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G7047_RS28365	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G7047_RS28375	COG1773	rubredoxin
G7047_RS28390	COG0835	chemotaxis
G7047_RS28395	COG0840	transmembrane signaling receptor activity
G7047_RS28400	COG0643	Histidine kinase
G7047_RS28400	COG0784	Response regulator, receiver
G7047_RS28400	COG2198	Histidine kinase
G7047_RS28405	COG1678	Uncharacterized ACR, COG1678
G7047_RS28410	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G7047_RS28415	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
G7047_RS28420	COG0540	Belongs to the ATCase OTCase family
G7047_RS28435	COG1393	Belongs to the ArsC family
G7047_RS28440	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G7047_RS28450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G7047_RS28460	COG0642	Histidine kinase
G7047_RS28495	COG4555	ABC transporter
G7047_RS28520	COG3813	Protein conserved in bacteria
G7047_RS28530	COG0729	surface antigen
G7047_RS28545	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G7047_RS28575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7047_RS28595	COG1414	Transcriptional regulator
G7047_RS28605	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G7047_RS28610	COG0183	Belongs to the thiolase family
G7047_RS28615	COG0596	Alpha beta hydrolase
G7047_RS28635	COG2031	fatty acid transporter
G7047_RS28640	COG4829	muconolactone delta-isomerase
G7047_RS28645	COG3181	Tripartite tricarboxylate transporter family receptor
G7047_RS28655	COG1280	lysine exporter protein (LysE YggA)
G7047_RS28660	COG1192	Involved in chromosome partitioning
G7047_RS28675	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G7047_RS28680	COG1040	competence protein
G7047_RS28685	COG2226	methyltransferase
G7047_RS28700	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
G7047_RS28720	COG3346	SURF1 family
G7047_RS28735	COG0109	protoheme IX farnesyltransferase activity
G7047_RS28740	COG1999	signal sequence binding
G7047_RS28750	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G7047_RS28755	COG2188	Transcriptional regulator
G7047_RS28760	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G7047_RS28780	COG1172	Belongs to the binding-protein-dependent transport system permease family
G7047_RS28785	COG0667	Aldo Keto reductase
G7047_RS28800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G7047_RS28835	COG0612	Peptidase, M16
G7047_RS28840	COG0612	Peptidase, M16
G7047_RS28845	COG0742	ribosomal rna small subunit methyltransferase
G7047_RS28855	COG0318	PFAM AMP-dependent synthetase and ligase
G7047_RS28860	COG3268	Saccharopine dehydrogenase
G7047_RS28890	COG0697	spore germination
G7047_RS28895	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G7047_RS28900	COG4607	ABC-type enterochelin transport system periplasmic component
G7047_RS28915	COG2823	Periplasmic or secreted lipoprotein
G7047_RS28925	COG5487	UPF0391 membrane protein
G7047_RS28930	COG4585	Histidine kinase
G7047_RS28935	COG2197	response regulator
G7047_RS28950	COG0793	Belongs to the peptidase S41A family
G7047_RS28955	COG0588	phosphoglycerate mutase activity
G7047_RS28960	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G7047_RS28970	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
G7047_RS28975	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G7047_RS28990	COG0583	DNA-binding transcription factor activity
G7047_RS28995	COG2814	Major facilitator Superfamily
G7047_RS29015	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G7047_RS29060	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G7047_RS29105	COG1349	DNA-binding transcription factor activity
G7047_RS29120	COG0583	DNA-binding transcription factor activity
G7047_RS29130	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G7047_RS29145	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G7047_RS29145	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G7047_RS29160	COG0489	protein tyrosine kinase activity
G7047_RS29165	COG0243	molybdopterin cofactor binding
G7047_RS29175	COG0385	Bile acid
G7047_RS29185	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
G7047_RS29210	COG1953	Uracil, thiamine, allantoin
G7047_RS29220	COG0493	'glutamate synthase
G7047_RS29225	COG1309	transcriptional regulator
G7047_RS29250	COG4695	Portal protein
G7047_RS29450	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G7047_RS29460	COG1252	NADH dehydrogenase
G7047_RS29580	COG1136	(ABC) transporter
G7047_RS29600	COG4680	protein conserved in bacteria
G7047_RS29630	COG4372	Transposase
G7047_RS29685	COG2826	transposase and inactivated derivatives, IS30 family
G7047_RS29705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G7047_RS29710	COG2721	sulfolactate sulfo-lyase activity
G7047_RS29715	COG0246	Mannitol dehydrogenase
G7047_RS29720	COG1063	alcohol dehydrogenase
G7047_RS29725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7047_RS29735	COG0765	amino acid transport
G7047_RS29805	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G7047_RS29850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7047_RS29880	COG0653	protein targeting
G7047_RS29910	COG4771	TonB-dependent receptor
G7047_RS29915	COG1429	ligase activity, forming nitrogen-metal bonds
G7047_RS29940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G7047_RS29945	COG1116	anion transmembrane transporter activity
G7047_RS30015	COG3550	peptidyl-serine autophosphorylation
G7047_RS30040	COG0789	Transcriptional regulator
G7047_RS30090	COG0583	DNA-binding transcription factor activity
G7047_RS30125	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G7047_RS30190	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G7047_RS30235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7047_RS30240	COG1309	transcriptional regulator
G7047_RS30270	COG0616	signal peptide processing
G7047_RS30375	COG2916	Histone family protein nucleoid-structuring protein H-NS
G7047_RS30415	COG1192	Involved in chromosome partitioning
G7047_RS30510	COG0681	Belongs to the peptidase S26 family
G7047_RS30555	COG0305	Participates in initiation and elongation during chromosome replication
G7047_RS30640	COG2826	transposase and inactivated derivatives, IS30 family
G7047_RS30670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7047_RS30750	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G7047_RS30765	COG4372	Transposase
G7047_RS30780	COG2801	Transposase and inactivated derivatives
G7047_RS30795	COG3041	Addiction module toxin RelE StbE family
G7047_RS30800	COG3077	Addiction module antitoxin, RelB DinJ family