locus-tag	class	description
B6N31_RS00010	COG0592	DNA-directed DNA polymerase activity
B6N31_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B6N31_RS00035	COG0742	ribosomal rna small subunit methyltransferase
B6N31_RS00040	COG0339	signal peptide processing
B6N31_RS00050	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
B6N31_RS00055	COG1234	tRNA 3'-trailer cleavage
B6N31_RS00060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B6N31_RS00065	COG0471	metal ion transport
B6N31_RS00070	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B6N31_RS00075	COG2188	Transcriptional regulator
B6N31_RS00085	COG1522	sequence-specific DNA binding
B6N31_RS00090	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
B6N31_RS00095	COG1509	lysine 2,3-aminomutase activity
B6N31_RS00115	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B6N31_RS00120	COG4191	Histidine kinase
B6N31_RS00140	COG0583	DNA-binding transcription factor activity
B6N31_RS00160	COG0837	glucose binding
B6N31_RS00175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B6N31_RS00180	COG4172	Belongs to the ABC transporter superfamily
B6N31_RS00195	COG0747	negative chemotaxis
B6N31_RS00205	COG3977	Valine--pyruvate aminotransferase
B6N31_RS00215	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B6N31_RS00220	COG0456	acetyltransferase
B6N31_RS00225	COG2818	Glycosylase
B6N31_RS00230	COG0730	response to heat
B6N31_RS00235	COG0752	glycyl-tRNA synthetase alpha subunit
B6N31_RS00240	COG0751	glycine-tRNA ligase activity
B6N31_RS00255	COG3501	Rhs element vgr protein
B6N31_RS00265	COG4104	PAAR repeat-containing protein
B6N31_RS00265	COG3209	COG3209 Rhs family protein
B6N31_RS00325	COG3842	ATPase activity
B6N31_RS00345	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
B6N31_RS00345	COG2213	PTS system mannitol-specific
B6N31_RS00350	COG0246	Mannitol dehydrogenase
B6N31_RS00355	COG3722	fumarate hydratase activity
B6N31_RS00360	COG0840	transmembrane signaling receptor activity
B6N31_RS00365	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B6N31_RS00370	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B6N31_RS00375	COG1012	belongs to the aldehyde dehydrogenase family
B6N31_RS00380	COG1070	Carbohydrate kinase
B6N31_RS00385	COG2115	Belongs to the xylose isomerase family
B6N31_RS00395	COG4213	ABC transporter substrate-binding protein
B6N31_RS00400	COG1129	ABC transporter
B6N31_RS00405	COG4214	carbohydrate transport
B6N31_RS00410	COG1609	Transcriptional regulator
B6N31_RS00410	COG2207	Transcriptional regulator
B6N31_RS00430	COG0137	argininosuccinate synthase activity
B6N31_RS00435	COG1846	Transcriptional regulator
B6N31_RS00440	COG0697	spore germination
B6N31_RS00445	COG2313	pseudouridylate synthase activity
B6N31_RS00450	COG0546	phosphoglycolate phosphatase activity
B6N31_RS00455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B6N31_RS00485	COG1917	Cupin 2, conserved barrel domain protein
B6N31_RS00485	COG2207	Transcriptional regulator
B6N31_RS00490	COG0577	efflux transmembrane transporter activity
B6N31_RS00490	COG1136	(ABC) transporter
B6N31_RS00495	COG1136	(ABC) transporter
B6N31_RS00495	COG0577	efflux transmembrane transporter activity
B6N31_RS00510	COG2091	lysine biosynthetic process via aminoadipic acid
B6N31_RS00535	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B6N31_RS00570	COG0318	PFAM AMP-dependent synthetase and ligase
B6N31_RS00595	COG2771	luxR family
B6N31_RS00600	COG3916	Acyl-homoserine-lactone synthase
B6N31_RS00650	COG3179	chitinase
B6N31_RS00665	COG0717	Belongs to the dCTP deaminase family
B6N31_RS00700	COG0582	viral genome integration into host DNA
B6N31_RS00705	COG1561	YicC-like family, N-terminal region
B6N31_RS00710	COG0583	DNA-binding transcription factor activity
B6N31_RS00720	COG0747	negative chemotaxis
B6N31_RS00725	COG0601	transmembrane transport
B6N31_RS00730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B6N31_RS00735	COG0444	Belongs to the ABC transporter superfamily
B6N31_RS00740	COG4608	Belongs to the ABC transporter superfamily
B6N31_RS00765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B6N31_RS00770	COG0601	transmembrane transport
B6N31_RS00775	COG0747	negative chemotaxis
B6N31_RS00780	COG4172	Belongs to the ABC transporter superfamily
B6N31_RS00785	COG4948	Mandelate Racemase Muconate Lactonizing
B6N31_RS00800	COG2149	membrane
B6N31_RS00805	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
B6N31_RS00810	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
B6N31_RS00815	COG1309	transcriptional regulator
B6N31_RS00820	COG0756	dUTP diphosphatase activity
B6N31_RS00825	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B6N31_RS00830	COG2003	Belongs to the UPF0758 family
B6N31_RS00845	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B6N31_RS00850	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
B6N31_RS00860	COG1519	Transferase
B6N31_RS00865	COG0438	transferase activity, transferring glycosyl groups
B6N31_RS00885	COG0859	PFAM glycosyl transferase family 9
B6N31_RS00890	COG0859	PFAM glycosyl transferase family 9
B6N31_RS00895	COG0859	PFAM glycosyl transferase family 9
B6N31_RS00900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B6N31_RS00905	COG0156	8-amino-7-oxononanoate synthase activity
B6N31_RS00910	COG1063	alcohol dehydrogenase
B6N31_RS00915	COG2861	carbohydrate metabolic process
B6N31_RS00920	COG4942	peptidase
B6N31_RS00925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B6N31_RS00930	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
B6N31_RS00935	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B6N31_RS00940	COG1045	serine acetyltransferase
B6N31_RS00955	COG0583	DNA-binding transcription factor activity
B6N31_RS00960	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B6N31_RS00965	COG0412	Dienelactone hydrolase
B6N31_RS00970	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
B6N31_RS00980	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
B6N31_RS00985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B6N31_RS00990	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B6N31_RS00995	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B6N31_RS01000	COG0165	Argininosuccinate lyase
B6N31_RS01005	COG1322	Protein conserved in bacteria
B6N31_RS01010	COG2226	methyltransferase
B6N31_RS01015	COG3165	ubiquinone biosynthetic process from chorismate
B6N31_RS01020	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B6N31_RS01025	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B6N31_RS01035	COG0805	protein transport
B6N31_RS01040	COG0084	hydrolase, TatD family'
B6N31_RS01055	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
B6N31_RS01065	COG0640	Transcriptional regulator
B6N31_RS01080	COG0183	Belongs to the thiolase family
B6N31_RS01085	COG1250	3-hydroxyacyl-CoA dehydrogenase
B6N31_RS01085	COG1024	Enoyl-CoA hydratase
B6N31_RS01090	COG0006	proline dipeptidase activity
B6N31_RS01095	COG1739	Uncharacterized protein family UPF0029
B6N31_RS01100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B6N31_RS01140	COG1072	(Pantothenic acid kinase))
B6N31_RS01170	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B6N31_RS01180	COG0250	Participates in transcription elongation, termination and antitermination
B6N31_RS01210	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B6N31_RS01230	COG5457	Domain of unknown function (DUF1127)
B6N31_RS01235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B6N31_RS01250	COG3157	Type VI secretion system effector, Hcp
B6N31_RS01255	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B6N31_RS01260	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
B6N31_RS01280	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B6N31_RS01285	COG2022	thiamine diphosphate biosynthetic process
B6N31_RS01290	COG2104	thiamine diphosphate biosynthetic process
B6N31_RS01295	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B6N31_RS01300	COG0352	thiamine-phosphate diphosphorylase activity
B6N31_RS01305	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B6N31_RS01310	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
B6N31_RS01315	COG2816	NAD+ diphosphatase activity
B6N31_RS01320	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
B6N31_RS01325	COG1515	deoxyribonuclease V activity
B6N31_RS01350	COG0151	Belongs to the GarS family
B6N31_RS01355	COG0138	bifunctional purine biosynthesis protein purh
B6N31_RS01395	COG1126	abc transporter atp-binding protein
B6N31_RS01400	COG0765	amino acid transport
B6N31_RS01405	COG4597	amino acid ABC transporter
B6N31_RS01410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B6N31_RS01415	COG0504	CTP synthase activity
B6N31_RS01420	COG0765	amino acid transport
B6N31_RS01425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B6N31_RS01435	COG4221	oxidoreductase activity
B6N31_RS01450	COG4221	oxidoreductase activity
B6N31_RS01455	COG1064	alcohol dehydrogenase
B6N31_RS01460	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
B6N31_RS01470	COG2264	protein methyltransferase activity
B6N31_RS01475	COG4145	pantothenate transmembrane transporter activity
B6N31_RS01480	COG3924	membrane
B6N31_RS01485	COG0439	Biotin carboxylase
B6N31_RS01490	COG0511	ligase activity, forming carbon-carbon bonds
B6N31_RS01495	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B6N31_RS01500	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
B6N31_RS01505	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B6N31_RS01510	COG0604	alcohol dehydrogenase
B6N31_RS01515	COG2199	diguanylate cyclase activity
B6N31_RS01515	COG2200	EAL domain
B6N31_RS01520	COG1077	Cell shape determining protein MreB Mrl
B6N31_RS01525	COG1792	Involved in formation and maintenance of cell shape
B6N31_RS01530	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
B6N31_RS01535	COG0424	maF-like protein
B6N31_RS01545	COG3164	Protein of unknown function
B6N31_RS01550	COG0312	modulator of DNA gyrase
B6N31_RS01555	COG0583	DNA-binding transcription factor activity
B6N31_RS01565	COG1566	PFAM secretion protein HlyD family protein
B6N31_RS01570	COG1289	transmembrane transporter activity
B6N31_RS01580	COG1280	lysine exporter protein (LysE YggA)
B6N31_RS01585	COG3028	Belongs to the UPF0307 family
B6N31_RS01590	COG0312	modulator of DNA gyrase
B6N31_RS01595	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B6N31_RS01600	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B6N31_RS01605	COG1660	Displays ATPase and GTPase activities
B6N31_RS01620	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B6N31_RS01625	COG1137	ATPase activity
B6N31_RS01630	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
B6N31_RS01635	COG3117	lipopolysaccharide transmembrane transporter activity
B6N31_RS01640	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
B6N31_RS01645	COG0517	IMP dehydrogenase activity
B6N31_RS01645	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
B6N31_RS01650	COG0530	calcium, potassium:sodium antiporter activity
B6N31_RS01655	COG1127	ABC transporter
B6N31_RS01660	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B6N31_RS01665	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B6N31_RS01670	COG2854	intermembrane phospholipid transfer
B6N31_RS01675	COG3113	response to antibiotic
B6N31_RS01680	COG5007	Belongs to the BolA IbaG family
B6N31_RS01685	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B6N31_RS01690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B6N31_RS01695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B6N31_RS01700	COG3105	Protein conserved in bacteria
B6N31_RS01705	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
B6N31_RS01725	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B6N31_RS01730	COG0625	glutathione transferase activity
B6N31_RS01735	COG2969	positive regulation of protein catabolic process
B6N31_RS01745	COG0493	'glutamate synthase
B6N31_RS01750	COG0069	glutamate synthase activity
B6N31_RS01750	COG0070	glutamate synthase
B6N31_RS01750	COG0067	glutamate synthase
B6N31_RS01755	COG1242	4 iron, 4 sulfur cluster binding
B6N31_RS01760	COG2198	Histidine kinase
B6N31_RS01760	COG5002	protein histidine kinase activity
B6N31_RS01760	COG0784	Response regulator, receiver
B6N31_RS01765	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
B6N31_RS01770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B6N31_RS01780	COG2823	Periplasmic or secreted lipoprotein
B6N31_RS01785	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
B6N31_RS01790	COG0792	nuclease activity
B6N31_RS01795	COG3107	peptidoglycan biosynthetic process
B6N31_RS01800	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
B6N31_RS01810	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B6N31_RS01815	COG3384	dioxygenase
B6N31_RS01820	COG0754	glutathionylspermidine amidase activity
B6N31_RS01825	COG5463	Belongs to the UPF0441 family
B6N31_RS01830	COG1538	Outer membrane efflux protein
B6N31_RS01835	COG0494	nUDIX hydrolase
B6N31_RS01840	COG3151	Protein conserved in bacteria
B6N31_RS01845	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B6N31_RS01850	COG3150	esterase
B6N31_RS01860	COG0583	DNA-binding transcription factor activity
B6N31_RS01865	COG2249	NAD(P)H dehydrogenase (quinone) activity
B6N31_RS01870	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B6N31_RS01875	COG0204	Acyl-transferase
B6N31_RS01880	COG2132	Multicopper oxidase
B6N31_RS01885	COG0656	L-ascorbic acid biosynthetic process
B6N31_RS01890	COG1979	alcohol dehydrogenase
B6N31_RS01895	COG0778	Nitroreductase
B6N31_RS01900	COG2207	Transcriptional regulator
B6N31_RS01910	COG0626	cystathionine gamma-synthase activity
B6N31_RS01915	COG0811	peptide transport
B6N31_RS01920	COG0848	biopolymer transport protein
B6N31_RS01975	COG1857	crispr-associated protein
B6N31_RS01990	COG1518	maintenance of DNA repeat elements
B6N31_RS01995	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B6N31_RS02000	COG0840	transmembrane signaling receptor activity
B6N31_RS02005	COG3311	Transcriptional regulator
B6N31_RS02010	COG1569	PIN domain
B6N31_RS02025	COG1328	CTP reductase activity
B6N31_RS02035	COG4166	transmembrane transport
B6N31_RS02040	COG0601	transmembrane transport
B6N31_RS02045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B6N31_RS02050	COG4172	Belongs to the ABC transporter superfamily
B6N31_RS02070	COG2308	Evidence 4 Homologs of previously reported genes of
B6N31_RS02090	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
B6N31_RS02095	COG0540	Belongs to the ATCase OTCase family
B6N31_RS02100	COG2731	YhcH YjgK YiaL family protein
B6N31_RS02105	COG2190	(PTS) system
B6N31_RS02105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B6N31_RS02105	COG1263	PTS System
B6N31_RS02110	COG2723	6-phospho-beta-galactosidase activity
B6N31_RS02115	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B6N31_RS02130	COG1396	sequence-specific DNA binding
B6N31_RS02135	COG0454	-acetyltransferase
B6N31_RS02140	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B6N31_RS02145	COG0840	transmembrane signaling receptor activity
B6N31_RS02150	COG0525	valine-tRNA ligase activity
B6N31_RS02155	COG2927	DNA polymerase III (CHI subunit)
B6N31_RS02160	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B6N31_RS02165	COG0795	lipopolysaccharide-transporting ATPase activity
B6N31_RS02170	COG0795	lipopolysaccharide-transporting ATPase activity
B6N31_RS02180	COG0582	viral genome integration into host DNA
B6N31_RS02190	COG3550	peptidyl-serine autophosphorylation
B6N31_RS02235	COG1401	restriction endodeoxyribonuclease activity
B6N31_RS02245	COG0732	type I restriction modification DNA specificity domain
B6N31_RS02250	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
B6N31_RS02265	COG2226	methyltransferase
B6N31_RS02295	COG1349	DNA-binding transcription factor activity
B6N31_RS02305	COG1129	ABC transporter
B6N31_RS02310	COG1172	Belongs to the binding-protein-dependent transport system permease family
B6N31_RS02315	COG1172	Belongs to the binding-protein-dependent transport system permease family
B6N31_RS02320	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B6N31_RS02330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B6N31_RS02345	COG2814	Major facilitator Superfamily
B6N31_RS02355	COG0747	negative chemotaxis
B6N31_RS02365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B6N31_RS02370	COG0444	Belongs to the ABC transporter superfamily
B6N31_RS02375	COG4608	Belongs to the ABC transporter superfamily
B6N31_RS02390	COG0583	DNA-binding transcription factor activity
B6N31_RS02410	COG1605	Chorismate mutase
B6N31_RS02420	COG1418	mRNA catabolic process
B6N31_RS02425	COG0659	secondary active sulfate transmembrane transporter activity
B6N31_RS02430	COG0288	reversible hydration of carbon dioxide
B6N31_RS02435	COG1414	Transcriptional regulator
B6N31_RS02440	COG0840	transmembrane signaling receptor activity
B6N31_RS02450	COG0235	Class ii aldolase
B6N31_RS02455	COG4806	L-rhamnose isomerase
B6N31_RS02460	COG1070	Carbohydrate kinase
B6N31_RS02465	COG1917	Cupin 2, conserved barrel domain protein
B6N31_RS02465	COG2169	Transcriptional regulator
B6N31_RS02470	COG4977	sequence-specific DNA binding
B6N31_RS02470	COG1917	Cupin 2, conserved barrel domain protein
B6N31_RS02490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B6N31_RS02500	COG0747	negative chemotaxis
B6N31_RS02505	COG3477	response to acidic pH
B6N31_RS02515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B6N31_RS02520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B6N31_RS02525	COG0006	proline dipeptidase activity
B6N31_RS02535	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
B6N31_RS02545	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B6N31_RS02560	COG0560	Phosphoserine phosphatase
B6N31_RS02565	COG3726	membrane protein affecting hemolysin expression
B6N31_RS02570	COG4106	trans-aconitate 2-methyltransferase activity
B6N31_RS02585	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
B6N31_RS02590	COG2823	Periplasmic or secreted lipoprotein
B6N31_RS02605	COG0084	hydrolase, TatD family'
B6N31_RS02620	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
B6N31_RS02625	COG0840	transmembrane signaling receptor activity
B6N31_RS02630	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
B6N31_RS02650	COG1473	amidohydrolase
B6N31_RS02660	COG1120	ATPase activity
B6N31_RS02670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B6N31_RS02680	COG3634	alkyl hydroperoxide reductase activity
B6N31_RS02695	COG2351	hydroxyisourate hydrolase activity
B6N31_RS02730	COG0789	Transcriptional regulator
B6N31_RS02735	COG1609	Transcriptional regulator
B6N31_RS02780	COG0297	glycogen (starch) synthase activity
B6N31_RS02785	COG0438	transferase activity, transferring glycosyl groups
B6N31_RS02785	COG0297	glycogen (starch) synthase activity
B6N31_RS02800	COG1045	serine acetyltransferase
B6N31_RS02810	COG1522	sequence-specific DNA binding
B6N31_RS02835	COG1309	transcriptional regulator
B6N31_RS02840	COG4232	protein-disulfide reductase activity
B6N31_RS02845	COG1324	tolerance protein
B6N31_RS02850	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
B6N31_RS02865	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B6N31_RS02870	COG0459	protein refolding
B6N31_RS02875	COG3161	chorismate lyase activity
B6N31_RS02880	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
B6N31_RS02885	COG2937	Belongs to the GPAT DAPAT family
B6N31_RS02890	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
B6N31_RS02895	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B6N31_RS02900	COG0735	belongs to the Fur family
B6N31_RS02905	COG1741	Belongs to the pirin family
B6N31_RS02910	COG0583	DNA-binding transcription factor activity
B6N31_RS02915	COG0435	Glutathione S-transferase
B6N31_RS02920	COG2259	Doxx family
B6N31_RS02930	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
B6N31_RS02935	COG4575	ribosome binding
B6N31_RS02945	COG0586	Pfam SNARE associated Golgi protein
B6N31_RS02955	COG2271	Major facilitator Superfamily
B6N31_RS02965	COG1904	glucuronate isomerase
B6N31_RS02970	COG0246	Mannitol dehydrogenase
B6N31_RS02975	COG2721	sulfolactate sulfo-lyase activity
B6N31_RS02985	COG0861	Integral membrane protein TerC family
B6N31_RS02990	COG2813	Specifically methylates the guanine in position
B6N31_RS03015	COG2197	response regulator
B6N31_RS03025	COG2271	Major facilitator Superfamily
B6N31_RS03035	COG3678	ATP-independent chaperone mediated protein folding
B6N31_RS03040	COG1477	protein flavinylation
B6N31_RS03065	COG0667	Aldo Keto reductase
B6N31_RS03070	COG0300	oxidoreductase activity
B6N31_RS03075	COG1028	Short-chain dehydrogenase reductase Sdr
B6N31_RS03095	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B6N31_RS03100	COG0358	DNA primase activity
B6N31_RS03105	COG0828	Belongs to the bacterial ribosomal protein bS21 family
B6N31_RS03110	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B6N31_RS03115	COG1438	arginine binding
B6N31_RS03125	COG3423	Transcriptional regulator
B6N31_RS03140	COG0142	geranyltranstransferase activity
B6N31_RS03145	COG0261	This protein binds to 23S rRNA in the presence of protein L20
B6N31_RS03155	COG0697	spore germination
B6N31_RS03160	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B6N31_RS03165	COG2027	D-alanyl-D-alanine carboxypeptidase
B6N31_RS03175	COG1534	Rna-binding protein
B6N31_RS03180	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
B6N31_RS03185	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B6N31_RS03190	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B6N31_RS03195	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B6N31_RS03200	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B6N31_RS03215	COG0779	Required for maturation of 30S ribosomal subunits
B6N31_RS03220	COG0195	Participates in both transcription termination and antitermination
B6N31_RS03225	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
B6N31_RS03230	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
B6N31_RS03235	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B6N31_RS03240	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B6N31_RS03245	COG1185	polyribonucleotide nucleotidyltransferase activity
B6N31_RS03260	COG0513	Belongs to the DEAD box helicase family
B6N31_RS03265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B6N31_RS03270	COG0826	peptidase U32
B6N31_RS03275	COG0826	peptidase U32
B6N31_RS03280	COG3154	lipid carrier protein
B6N31_RS03285	COG3153	acetyltransferase
B6N31_RS03295	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
B6N31_RS03300	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
B6N31_RS03305	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
B6N31_RS03310	COG0813	purine-nucleoside phosphorylase activity
B6N31_RS03315	COG4178	(ABC) transporter
B6N31_RS03330	COG1595	DNA-templated transcription, initiation
B6N31_RS03335	COG0456	acetyltransferase
B6N31_RS03340	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
B6N31_RS03345	COG2813	Specifically methylates the guanine in position
B6N31_RS03350	COG0667	Aldo Keto reductase
B6N31_RS03355	COG0583	DNA-binding transcription factor activity
B6N31_RS03395	COG1454	alcohol dehydrogenase
B6N31_RS03400	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B6N31_RS03405	COG0509	glycine decarboxylation via glycine cleavage system
B6N31_RS03410	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B6N31_RS03410	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B6N31_RS03415	COG1280	lysine exporter protein (LysE YggA)
B6N31_RS03425	COG1272	protein, Hemolysin III
B6N31_RS03430	COG0354	folic acid binding
B6N31_RS03435	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
B6N31_RS03445	COG0716	FMN binding
B6N31_RS03450	COG0477	Major facilitator Superfamily
B6N31_RS03455	COG4974	Belongs to the 'phage' integrase family
B6N31_RS03460	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B6N31_RS03465	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B6N31_RS03495	COG2020	methyltransferase activity
B6N31_RS03510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B6N31_RS03530	COG0671	phosphoesterase, PA-phosphatase related
B6N31_RS03535	COG1733	regulation of RNA biosynthetic process
B6N31_RS03550	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B6N31_RS03565	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B6N31_RS03570	COG0395	ABC-type sugar transport system, permease component
B6N31_RS03575	COG1175	transmembrane transport
B6N31_RS03585	COG1560	Kdo2-lipid A biosynthetic process
B6N31_RS03590	COG2252	PERMEase
B6N31_RS03595	COG0025	NhaP-type Na H and K H
B6N31_RS03600	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B6N31_RS03605	COG3162	membrane
B6N31_RS03610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B6N31_RS03625	COG4948	Mandelate Racemase Muconate Lactonizing
B6N31_RS03630	COG0747	negative chemotaxis
B6N31_RS03635	COG0601	transmembrane transport
B6N31_RS03640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B6N31_RS03645	COG0444	Belongs to the ABC transporter superfamily
B6N31_RS03650	COG4608	Belongs to the ABC transporter superfamily
B6N31_RS03665	COG3712	iron ion homeostasis
B6N31_RS03705	COG0246	Mannitol dehydrogenase
B6N31_RS03710	COG2814	Major facilitator Superfamily
B6N31_RS03720	COG1846	Transcriptional regulator
B6N31_RS03725	COG1376	ErfK ybiS ycfS ynhG family protein
B6N31_RS03730	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B6N31_RS03730	COG1013	pyruvate-flavodoxin oxidoreductase activity
B6N31_RS03730	COG0674	pyruvate-flavodoxin oxidoreductase activity
B6N31_RS03730	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
B6N31_RS03760	COG2211	Major facilitator Superfamily
B6N31_RS03785	COG1181	Belongs to the D-alanine--D-alanine ligase family
B6N31_RS03810	COG2814	Major facilitator Superfamily
B6N31_RS03815	COG0583	DNA-binding transcription factor activity
B6N31_RS03835	COG3962	Belongs to the TPP enzyme family
B6N31_RS03840	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
B6N31_RS03875	COG0673	inositol 2-dehydrogenase activity
B6N31_RS03890	COG1172	Belongs to the binding-protein-dependent transport system permease family
B6N31_RS03900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B6N31_RS03910	COG3718	enzyme involved in inositol metabolism
B6N31_RS03925	COG2951	lytic endotransglycosylase activity
B6N31_RS03930	COG0583	DNA-binding transcription factor activity
B6N31_RS03935	COG2271	Major facilitator Superfamily
B6N31_RS03940	COG4948	Mandelate Racemase Muconate Lactonizing
B6N31_RS04000	COG2867	negative regulation of translational initiation
B6N31_RS04005	COG2914	Belongs to the UPF0125 (RnfH) family
B6N31_RS04015	COG0497	DNA recombination
B6N31_RS04020	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B6N31_RS04030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B6N31_RS04035	COG1914	H( )-stimulated, divalent metal cation uptake system
B6N31_RS04040	COG0494	nUDIX hydrolase
B6N31_RS04045	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B6N31_RS04055	COG1671	Belongs to the UPF0178 family
B6N31_RS04060	COG0408	coproporphyrinogen oxidase activity
B6N31_RS04065	COG0456	acetyltransferase
B6N31_RS04070	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
B6N31_RS04075	COG4771	TonB-dependent receptor
B6N31_RS04080	COG0612	Peptidase, M16
B6N31_RS04085	COG4178	(ABC) transporter
B6N31_RS04100	COG3423	Transcriptional regulator
B6N31_RS04115	COG2837	iron assimilation
B6N31_RS04125	COG1136	(ABC) transporter
B6N31_RS04125	COG0577	efflux transmembrane transporter activity
B6N31_RS04130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B6N31_RS04135	COG0745	RESPONSE REGULATOR receiver
B6N31_RS04140	COG2205	protein histidine kinase activity
B6N31_RS04145	COG2190	(PTS) system
B6N31_RS04155	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B6N31_RS04165	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B6N31_RS04170	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
B6N31_RS04175	COG3115	cell septum assembly
B6N31_RS04180	COG0531	amino acid
B6N31_RS04190	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B6N31_RS04200	COG0446	pyridine nucleotide-disulphide oxidoreductase
B6N31_RS04205	COG1773	rubredoxin
B6N31_RS04205	COG0426	domain, Protein
B6N31_RS04210	COG3604	Transcriptional regulator
B6N31_RS04215	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B6N31_RS04215	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
B6N31_RS04240	COG1053	succinate dehydrogenase
B6N31_RS04240	COG0431	NADPH-dependent FMN reductase
B6N31_RS04240	COG3976	FMN-binding domain protein
B6N31_RS04245	COG1053	succinate dehydrogenase
B6N31_RS04245	COG3976	FMN-binding domain protein
B6N31_RS04245	COG0431	NADPH-dependent FMN reductase
B6N31_RS04250	COG0477	Major facilitator Superfamily
B6N31_RS04255	COG3301	Polysulphide reductase, NrfD
B6N31_RS04260	COG0437	4 iron, 4 sulfur cluster binding
B6N31_RS04275	COG1609	Transcriptional regulator
B6N31_RS04280	COG1234	tRNA 3'-trailer cleavage
B6N31_RS04295	COG1175	transmembrane transport
B6N31_RS04300	COG1653	transport
B6N31_RS04320	COG0473	3-isopropylmalate dehydrogenase activity
B6N31_RS04325	COG0583	DNA-binding transcription factor activity
B6N31_RS04330	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B6N31_RS04330	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B6N31_RS04350	COG2862	Uncharacterized protein family, UPF0114
B6N31_RS04390	COG0745	RESPONSE REGULATOR receiver
B6N31_RS04395	COG5002	protein histidine kinase activity
B6N31_RS04405	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B6N31_RS04415	COG1733	regulation of RNA biosynthetic process
B6N31_RS04455	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
B6N31_RS04460	COG0577	efflux transmembrane transporter activity
B6N31_RS04460	COG1136	(ABC) transporter
B6N31_RS04470	COG0577	efflux transmembrane transporter activity
B6N31_RS04470	COG1136	(ABC) transporter
B6N31_RS04545	COG0534	Mate efflux family protein
B6N31_RS04570	COG4221	oxidoreductase activity
B6N31_RS04585	COG3423	Transcriptional regulator
B6N31_RS04615	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B6N31_RS04620	COG1002	Type II restriction enzyme, methylase subunits
B6N31_RS04625	COG1061	Type III restriction enzyme res subunit
B6N31_RS04630	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B6N31_RS04660	COG0582	viral genome integration into host DNA
B6N31_RS04670	COG1982	Orn Lys Arg decarboxylase major
B6N31_RS04680	COG0741	lytic transglycosylase activity
B6N31_RS04685	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
B6N31_RS04695	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B6N31_RS04700	COG3171	Protein conserved in bacteria
B6N31_RS04720	COG0667	Aldo Keto reductase
B6N31_RS04730	COG0861	Integral membrane protein TerC family
B6N31_RS04735	COG3066	DNA modification
B6N31_RS04745	COG0494	nUDIX hydrolase
B6N31_RS04755	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B6N31_RS04760	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
B6N31_RS04765	COG2165	general secretion pathway protein
B6N31_RS04770	COG4795	General secretion pathway protein
B6N31_RS04785	COG1025	Belongs to the peptidase M16 family
B6N31_RS04790	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B6N31_RS04790	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
B6N31_RS04795	COG0860	N-Acetylmuramoyl-L-alanine amidase
B6N31_RS04810	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
B6N31_RS04815	COG0456	acetyltransferase
B6N31_RS04825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B6N31_RS04835	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B6N31_RS04840	COG2166	iron-sulfur cluster assembly
B6N31_RS04845	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B6N31_RS04855	COG0583	DNA-binding transcription factor activity
B6N31_RS04860	COG2363	Small membrane protein
B6N31_RS04865	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
B6N31_RS04870	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B6N31_RS04875	COG1611	Belongs to the LOG family
B6N31_RS04905	COG2171	N-acyltransferase activity
B6N31_RS04910	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
B6N31_RS04925	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B6N31_RS04930	COG0528	UMP kinase activity
B6N31_RS04935	COG0233	cytoplasmic translational termination
B6N31_RS04940	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B6N31_RS04945	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B6N31_RS04950	COG0575	Belongs to the CDS family
B6N31_RS04955	COG0750	zinc metalloprotease
B6N31_RS04960	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B6N31_RS04965	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
B6N31_RS04970	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B6N31_RS04975	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B6N31_RS04980	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B6N31_RS04985	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B6N31_RS04990	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B6N31_RS04995	COG0587	DNA-directed DNA polymerase activity
B6N31_RS05000	COG0825	malonyl-CoA metabolic process
B6N31_RS05005	COG0346	lactoylglutathione lyase activity
B6N31_RS05010	COG0037	tRNA processing
B6N31_RS05015	COG4568	rho-dependent transcription termination
B6N31_RS05025	COG4681	YaeQ
B6N31_RS05030	COG3015	lipoprotein NlpE involved in copper resistance
B6N31_RS05035	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
B6N31_RS05050	COG1733	regulation of RNA biosynthetic process
B6N31_RS05080	COG0778	Nitroreductase
B6N31_RS05095	COG1881	PFAM PEBP family protein
B6N31_RS05125	COG2192	nodulation
B6N31_RS05150	COG2423	ornithine cyclodeaminase activity
B6N31_RS05160	COG0583	DNA-binding transcription factor activity
B6N31_RS05175	COG0546	phosphoglycolate phosphatase activity
B6N31_RS05190	COG2824	Alkylphosphonate utilization operon protein PhnA
B6N31_RS05195	COG3706	GGDEF domain
B6N31_RS05220	COG0583	DNA-binding transcription factor activity
B6N31_RS05245	COG0583	DNA-binding transcription factor activity
B6N31_RS05260	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B6N31_RS05265	COG4615	Cyclic peptide transporter
B6N31_RS05280	COG3123	guanosine phosphorylase activity
B6N31_RS05285	COG0840	transmembrane signaling receptor activity
B6N31_RS05295	COG2974	May be involved in recombination
B6N31_RS05300	COG1940	carbohydrate kinase activity
B6N31_RS05305	COG0419	ATPase involved in DNA repair
B6N31_RS05310	COG0420	3'-5' exonuclease activity
B6N31_RS05320	COG5002	protein histidine kinase activity
B6N31_RS05330	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B6N31_RS05345	COG0450	alkyl hydroperoxide reductase
B6N31_RS05350	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
B6N31_RS05355	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
B6N31_RS05360	COG0343	queuine tRNA-ribosyltransferase activity
B6N31_RS05365	COG1862	Preprotein translocase
B6N31_RS05370	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B6N31_RS05375	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B6N31_RS05380	COG4238	major outer membrane lipoprotein
B6N31_RS05385	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B6N31_RS05390	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B6N31_RS05395	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B6N31_RS05395	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B6N31_RS05400	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B6N31_RS05405	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B6N31_RS05410	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
B6N31_RS05415	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B6N31_RS05420	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B6N31_RS05425	COG0142	geranyltranstransferase activity
B6N31_RS05430	COG1722	exodeoxyribonuclease VII activity
B6N31_RS05435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B6N31_RS05435	COG0301	tRNA thio-modification
B6N31_RS05440	COG0693	protein deglycase activity
B6N31_RS05445	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B6N31_RS05450	COG1666	GTP binding
B6N31_RS05465	COG2814	Major facilitator Superfamily
B6N31_RS05485	COG0109	protoheme IX farnesyltransferase activity
B6N31_RS05490	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B6N31_RS05495	COG1845	cytochrome c oxidase, subunit III
B6N31_RS05500	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B6N31_RS05505	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B6N31_RS05510	COG2223	nitrite transmembrane transporter activity
B6N31_RS05515	COG3056	Lipoprotein
B6N31_RS05520	COG0271	Belongs to the BolA IbaG family
B6N31_RS05525	COG0544	peptidyl-prolyl cis-trans isomerase activity
B6N31_RS05530	COG0740	serine-type endopeptidase activity
B6N31_RS05535	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B6N31_RS05540	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B6N31_RS05545	COG0776	regulation of translation
B6N31_RS05550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B6N31_RS05555	COG1555	photosystem II stabilization
B6N31_RS05560	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
B6N31_RS05570	COG1522	sequence-specific DNA binding
B6N31_RS05575	COG1132	(ABC) transporter
B6N31_RS05580	COG1132	(ABC) transporter
B6N31_RS05585	COG0347	Belongs to the P(II) protein family
B6N31_RS05590	COG0004	ammonium transporteR
B6N31_RS05595	COG1946	Acyl-CoA thioesterase
B6N31_RS05600	COG3126	Type III secretion system lipoprotein chaperone (YscW)
B6N31_RS05605	COG3695	enzyme binding
B6N31_RS05625	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B6N31_RS05630	COG0254	rRNA binding
B6N31_RS05635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B6N31_RS05640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B6N31_RS05645	COG1309	transcriptional regulator
B6N31_RS05650	COG1196	nuclear chromosome segregation
B6N31_RS05650	COG3264	Mechanosensitive ion channel
B6N31_RS05670	COG2832	Protein of unknown function (DUF454)
B6N31_RS05675	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B6N31_RS05685	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B6N31_RS05690	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B6N31_RS05695	COG0326	Molecular chaperone. Has ATPase activity
B6N31_RS05700	COG0563	adenylate kinase activity
B6N31_RS05705	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
B6N31_RS05710	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B6N31_RS05710	COG4651	solute:proton antiporter activity
B6N31_RS05715	COG0737	Belongs to the 5'-nucleotidase family
B6N31_RS05730	COG0840	transmembrane signaling receptor activity
B6N31_RS05740	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B6N31_RS05745	COG3735	TraB family
B6N31_RS05750	COG2217	Heavy metal translocating P-type atpase
B6N31_RS05755	COG0789	Transcriptional regulator
B6N31_RS05760	COG1585	Membrane protein implicated in regulation of membrane protease activity
B6N31_RS05765	COG0330	HflC and HflK could
B6N31_RS05770	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B6N31_RS05780	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B6N31_RS05785	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B6N31_RS05795	COG2205	protein histidine kinase activity
B6N31_RS05795	COG0784	Response regulator, receiver
B6N31_RS05805	COG0642	Histidine kinase
B6N31_RS05805	COG2198	Histidine kinase
B6N31_RS05810	COG2223	nitrite transmembrane transporter activity
B6N31_RS05815	COG1169	isochorismate synthase
B6N31_RS05820	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
B6N31_RS05825	COG0596	Alpha beta hydrolase
B6N31_RS05835	COG1441	menaquinone biosynthetic process
B6N31_RS05855	COG3118	belongs to the thioredoxin family
B6N31_RS05860	COG0300	oxidoreductase activity
B6N31_RS05865	COG2755	lipolytic protein G-D-S-L family
B6N31_RS05870	COG4181	ATPase activity
B6N31_RS05875	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
B6N31_RS05880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B6N31_RS05890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B6N31_RS05895	COG0765	amino acid transport
B6N31_RS05900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B6N31_RS05935	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B6N31_RS05940	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B6N31_RS05945	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B6N31_RS05950	COG2233	PERMEase
B6N31_RS05955	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B6N31_RS05960	COG1393	Belongs to the ArsC family
B6N31_RS05965	COG4783	chaperone-mediated protein folding
B6N31_RS05970	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B6N31_RS05975	COG2716	regulation of RNA biosynthetic process
B6N31_RS05985	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
B6N31_RS05990	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B6N31_RS05995	COG2707	UPF0756 membrane protein
B6N31_RS06000	COG1444	tRNA N-acetyltransferase activity
B6N31_RS06005	COG0400	carboxylic ester hydrolase activity
B6N31_RS06015	COG1876	peptidase activity
B6N31_RS06020	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B6N31_RS06025	COG1393	Belongs to the ArsC family
B6N31_RS06030	COG1794	racemase activity, acting on amino acids and derivatives
B6N31_RS06040	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B6N31_RS06045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B6N31_RS06050	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B6N31_RS06055	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B6N31_RS06060	COG0321	lipoyl(octanoyl) transferase activity
B6N31_RS06065	COG2921	Belongs to the UPF0250 family
B6N31_RS06070	COG1686	Belongs to the peptidase S11 family
B6N31_RS06075	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B6N31_RS06080	COG0772	Belongs to the SEDS family
B6N31_RS06085	COG0768	penicillin binding
B6N31_RS06090	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
B6N31_RS06095	COG0799	negative regulation of ribosome biogenesis
B6N31_RS06100	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B6N31_RS06105	COG1466	dna polymerase III delta subunit
B6N31_RS06110	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
B6N31_RS06115	COG0495	leucyl-tRNA aminoacylation
B6N31_RS06120	COG2888	peptidyl-tyrosine sulfation
B6N31_RS06125	COG1126	abc transporter atp-binding protein
B6N31_RS06130	COG0765	amino acid transport
B6N31_RS06135	COG0765	amino acid transport
B6N31_RS06145	COG0815	Transfers the fatty acyl group on membrane lipoproteins
B6N31_RS06150	COG4535	Mg2 and Co2 transporter CorC
B6N31_RS06155	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B6N31_RS06160	COG1702	phosphate starvation-inducible protein PhoH
B6N31_RS06165	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B6N31_RS06170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B6N31_RS06215	COG0367	asparagine synthase
B6N31_RS06220	COG1846	Transcriptional regulator
B6N31_RS06220	COG1940	carbohydrate kinase activity
B6N31_RS06225	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B6N31_RS06230	COG0363	glucosamine-6-phosphate deaminase activity
B6N31_RS06235	COG1263	PTS System
B6N31_RS06235	COG2190	(PTS) system
B6N31_RS06235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B6N31_RS06240	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B6N31_RS06245	COG0735	belongs to the Fur family
B6N31_RS06250	COG0716	FMN binding
B6N31_RS06255	COG0840	transmembrane signaling receptor activity
B6N31_RS06265	COG0596	Alpha beta hydrolase
B6N31_RS06275	COG0033	Phosphoglucomutase
B6N31_RS06285	COG0745	RESPONSE REGULATOR receiver
B6N31_RS06290	COG2205	protein histidine kinase activity
B6N31_RS06295	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
B6N31_RS06300	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
B6N31_RS06305	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
B6N31_RS06320	COG3272	Protein of unknown function (DUF1722)
B6N31_RS06325	COG0415	Belongs to the DNA photolyase family
B6N31_RS06330	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B6N31_RS06335	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
B6N31_RS06340	COG1984	allophanate hydrolase subunit 2
B6N31_RS06345	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
B6N31_RS06355	COG0372	Belongs to the citrate synthase family
B6N31_RS06365	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
B6N31_RS06370	COG1053	succinate dehydrogenase
B6N31_RS06375	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B6N31_RS06380	COG0567	Dehydrogenase, E1 component
B6N31_RS06385	COG0508	dehydrogenase complex catalyzes the overall conversion of
B6N31_RS06390	COG0045	succinate-CoA ligase (ADP-forming) activity
B6N31_RS06395	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B6N31_RS06400	COG1271	oxidase subunit
B6N31_RS06405	COG1294	oxidase, subunit
B6N31_RS06410	COG4890	Cyd operon protein YbgT
B6N31_RS06415	COG3790	cyd operon protein YbgE
B6N31_RS06420	COG0824	Thioesterase
B6N31_RS06425	COG0811	peptide transport
B6N31_RS06430	COG0848	biopolymer transport protein
B6N31_RS06435	COG3064	Membrane
B6N31_RS06440	COG0823	Involved in the tonB-independent uptake of proteins
B6N31_RS06445	COG2885	chlorophyll binding
B6N31_RS06450	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
B6N31_RS06475	COG1811	Na channel or pump
B6N31_RS06480	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
B6N31_RS06490	COG1230	cation diffusion facilitator family transporter
B6N31_RS06495	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B6N31_RS06500	COG0588	phosphoglycerate mutase activity
B6N31_RS06505	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B6N31_RS06510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B6N31_RS06530	COG2017	converts alpha-aldose to the beta-anomer
B6N31_RS06540	COG1085	galactose-1-phosphate uridylyltransferase
B6N31_RS06545	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B6N31_RS06550	COG1119	ATPase activity
B6N31_RS06555	COG2005	Transcriptional regulator
B6N31_RS06555	COG3585	molybdate ion transport
B6N31_RS06565	COG0725	ABC transporter, periplasmic molybdate-binding protein
B6N31_RS06570	COG4149	molybdate abc transporter
B6N31_RS06575	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
B6N31_RS06580	COG0561	phosphatase activity
B6N31_RS06585	COG2706	6-phosphogluconolactonase activity
B6N31_RS06605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B6N31_RS06605	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B6N31_RS06610	COG0489	protein tyrosine kinase activity
B6N31_RS06620	COG0717	Belongs to the dCTP deaminase family
B6N31_RS06625	COG2982	Protein involved in outer membrane biogenesis
B6N31_RS06630	COG1253	flavin adenine dinucleotide binding
B6N31_RS06680	COG1088	dTDP-glucose 4,6-dehydratase activity
B6N31_RS06700	COG1215	transferase activity, transferring glycosyl groups
B6N31_RS06705	COG2244	polysaccharide biosynthetic process
B6N31_RS06735	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B6N31_RS06765	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B6N31_RS06780	COG3706	GGDEF domain
B6N31_RS06800	COG2990	Protein conserved in bacteria
B6N31_RS06810	COG3720	iron ion transport
B6N31_RS06815	COG4558	Periplasmic binding protein
B6N31_RS06820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B6N31_RS06825	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
B6N31_RS06835	COG2706	6-phosphogluconolactonase activity
B6N31_RS06840	COG0783	Belongs to the Dps family
B6N31_RS06860	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B6N31_RS06880	COG0443	Heat shock 70 kDa protein
B6N31_RS06890	COG3501	Rhs element vgr protein
B6N31_RS06970	COG1473	amidohydrolase
B6N31_RS07025	COG3829	transcription factor binding
B6N31_RS07065	COG4948	Mandelate Racemase Muconate Lactonizing
B6N31_RS07075	COG5001	Diguanylate cyclase
B6N31_RS07075	COG4251	negative regulation of phosphorylation
B6N31_RS07075	COG3706	GGDEF domain
B6N31_RS07075	COG2203	Gaf domain
B6N31_RS07080	COG0672	)-iron permease
B6N31_RS07095	COG3813	Protein conserved in bacteria
B6N31_RS07100	COG0477	Major facilitator Superfamily
B6N31_RS07115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B6N31_RS07120	COG1136	(ABC) transporter
B6N31_RS07120	COG0577	efflux transmembrane transporter activity
B6N31_RS07140	COG3321	synthase
B6N31_RS07140	COG1028	Short-chain dehydrogenase reductase Sdr
B6N31_RS07140	COG0604	alcohol dehydrogenase
B6N31_RS07145	COG2070	2-Nitropropane dioxygenase
B6N31_RS07145	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B6N31_RS07150	COG1028	Short-chain dehydrogenase reductase Sdr
B6N31_RS07180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B6N31_RS07200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B6N31_RS07205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B6N31_RS07210	COG0745	RESPONSE REGULATOR receiver
B6N31_RS07235	COG0730	response to heat
B6N31_RS07240	COG0488	(ABC) transporter
B6N31_RS07245	COG1556	Lactate utilization protein
B6N31_RS07250	COG1139	Iron-sulfur cluster binding protein
B6N31_RS07255	COG0247	lactate metabolic process
B6N31_RS07260	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B6N31_RS07275	COG1346	cytolysis
B6N31_RS07285	COG4566	intracellular signal transduction
B6N31_RS07290	COG4191	Histidine kinase
B6N31_RS07295	COG1116	anion transmembrane transporter activity
B6N31_RS07300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B6N31_RS07305	COG1285	pathogenesis
B6N31_RS07310	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
B6N31_RS07320	COG0768	penicillin binding
B6N31_RS07325	COG2890	protein-(glutamine-N5) methyltransferase activity
B6N31_RS07330	COG0747	negative chemotaxis
B6N31_RS07335	COG0601	transmembrane transport
B6N31_RS07345	COG0444	Belongs to the ABC transporter superfamily
B6N31_RS07350	COG1124	(ABC) transporter
B6N31_RS07355	COG1846	Transcriptional regulator
B6N31_RS07360	COG1566	PFAM secretion protein HlyD family protein
B6N31_RS07365	COG2814	Major facilitator Superfamily
B6N31_RS07370	COG3708	Transcriptional regulator
B6N31_RS07370	COG2207	Transcriptional regulator
B6N31_RS07375	COG3961	Belongs to the TPP enzyme family
B6N31_RS07390	COG3615	Tellurite resistance protein tehB
B6N31_RS07400	COG2814	Major facilitator Superfamily
B6N31_RS07420	COG0697	spore germination
B6N31_RS07425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B6N31_RS07435	COG1984	allophanate hydrolase subunit 2
B6N31_RS07440	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
B6N31_RS07455	COG0436	Aminotransferase
B6N31_RS07470	COG4221	oxidoreductase activity
B6N31_RS07475	COG0765	amino acid transport
B6N31_RS07480	COG0765	amino acid transport
B6N31_RS07495	COG3250	beta-galactosidase activity
B6N31_RS07500	COG1609	Transcriptional regulator
B6N31_RS07510	COG0583	DNA-binding transcription factor activity
B6N31_RS07515	COG1301	dicarboxylic acid transport
B6N31_RS07525	COG3383	formate dehydrogenase (NAD+) activity
B6N31_RS07530	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B6N31_RS07555	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
B6N31_RS07565	COG3260	NADH ubiquinone oxidoreductase 20
B6N31_RS07570	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B6N31_RS07575	COG3261	NADH dehydrogenase
B6N31_RS07575	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
B6N31_RS07580	COG0651	ATP synthesis coupled electron transport
B6N31_RS07585	COG4237	Hydrogenase 4 membrane
B6N31_RS07590	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B6N31_RS07595	COG0650	Formate hydrogenlyase subunit 4
B6N31_RS07600	COG0651	ATP synthesis coupled electron transport
B6N31_RS07605	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B6N31_RS07610	COG0298	carbon dioxide binding
B6N31_RS07625	COG0697	spore germination
B6N31_RS07630	COG0583	DNA-binding transcription factor activity
B6N31_RS07635	COG1301	dicarboxylic acid transport
B6N31_RS07640	COG1434	Gram-negative-bacterium-type cell wall biogenesis
B6N31_RS07650	COG0625	glutathione transferase activity
B6N31_RS07655	COG0625	glutathione transferase activity
B6N31_RS07665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B6N31_RS07670	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
B6N31_RS07680	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B6N31_RS07685	COG2515	1-aminocyclopropane-1-carboxylate deaminase
B6N31_RS07695	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
B6N31_RS07705	COG1012	belongs to the aldehyde dehydrogenase family
B6N31_RS07710	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B6N31_RS07740	COG2188	Transcriptional regulator
B6N31_RS07745	COG3624	Phosphonate C-P lyase system protein PhnG
B6N31_RS07750	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
B6N31_RS07755	COG3626	phosphonate metabolism
B6N31_RS07760	COG3627	carbon phosphorus lyase activity
B6N31_RS07765	COG4107	phosphonate C-P lyase system protein PhnK
B6N31_RS07770	COG4778	phosphonate C-P lyase system protein PhnL
B6N31_RS07775	COG3454	Phosphonate metabolism
B6N31_RS07780	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
B6N31_RS07785	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
B6N31_RS07795	COG0583	DNA-binding transcription factor activity
B6N31_RS07805	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
B6N31_RS07815	COG3639	organic phosphonate transmembrane transporter activity
B6N31_RS07820	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B6N31_RS07835	COG0019	diaminopimelate decarboxylase activity
B6N31_RS07840	COG2814	Major facilitator Superfamily
B6N31_RS07845	COG4264	IucA IucC family
B6N31_RS07855	COG4264	IucA IucC family
B6N31_RS07865	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B6N31_RS07870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B6N31_RS07875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B6N31_RS07880	COG1120	ATPase activity
B6N31_RS07885	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B6N31_RS07910	COG3383	formate dehydrogenase (NAD+) activity
B6N31_RS07910	COG0243	molybdopterin cofactor binding
B6N31_RS07915	COG0437	4 iron, 4 sulfur cluster binding
B6N31_RS07920	COG2864	formate dehydrogenase
B6N31_RS07935	COG2211	Major facilitator Superfamily
B6N31_RS07960	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B6N31_RS07965	COG1473	amidohydrolase
B6N31_RS07970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B6N31_RS07985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B6N31_RS07990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B6N31_RS08000	COG2199	diguanylate cyclase activity
B6N31_RS08005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B6N31_RS08025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B6N31_RS08050	COG3416	Protein conserved in bacteria
B6N31_RS08070	COG2011	ABC-type metal ion transport system permease component
B6N31_RS08130	COG4166	transmembrane transport
B6N31_RS08140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B6N31_RS08145	COG1957	nucleoside hydrolase
B6N31_RS08150	COG1957	nucleoside hydrolase
B6N31_RS08155	COG0601	transmembrane transport
B6N31_RS08175	COG0174	glutamine synthetase
B6N31_RS08190	COG2964	Protein conserved in bacteria
B6N31_RS08200	COG0784	Response regulator, receiver
B6N31_RS08200	COG0835	chemotaxis
B6N31_RS08235	COG0679	Auxin Efflux Carrier
B6N31_RS08245	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B6N31_RS08255	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B6N31_RS08260	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B6N31_RS08265	COG1121	(ABC) transporter
B6N31_RS08270	COG0803	Belongs to the bacterial solute-binding protein 9 family
B6N31_RS08280	COG1979	alcohol dehydrogenase
B6N31_RS08315	COG4227	nucleotidyltransferase activity
B6N31_RS08360	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
B6N31_RS08370	COG3504	Conjugal transfer protein
B6N31_RS08375	COG3736	Type IV secretory pathway, component VirB8
B6N31_RS08415	COG1002	Type II restriction enzyme, methylase subunits
B6N31_RS08420	COG1061	Type III restriction enzyme res subunit
B6N31_RS08425	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B6N31_RS08445	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B6N31_RS08470	COG3423	Transcriptional regulator
B6N31_RS08480	COG3501	Rhs element vgr protein
B6N31_RS08510	COG5489	Protein of unknown function (DUF736)
B6N31_RS08515	COG0582	viral genome integration into host DNA
B6N31_RS08525	COG3228	Belongs to the MtfA family
B6N31_RS08545	COG0401	homolog of Blt101
B6N31_RS08555	COG0457	Tetratricopeptide repeat
B6N31_RS08555	COG0463	Glycosyl transferase, family 2
B6N31_RS08565	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B6N31_RS08570	COG0303	'Molybdopterin
B6N31_RS08575	COG0281	malic enzyme
B6N31_RS08580	COG0295	cytidine deaminase activity
B6N31_RS08590	COG1346	cytolysis
B6N31_RS08595	COG1380	Effector of murein hydrolase LrgA
B6N31_RS08610	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B6N31_RS08615	COG0156	8-amino-7-oxononanoate synthase activity
B6N31_RS08620	COG2226	methyltransferase
B6N31_RS08630	COG0556	nucleotide-excision repair
B6N31_RS08640	COG0391	Required for morphogenesis under gluconeogenic growth conditions
B6N31_RS08645	COG1271	oxidase subunit
B6N31_RS08650	COG1294	oxidase, subunit
B6N31_RS08660	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B6N31_RS08665	COG0521	Mo-molybdopterin cofactor biosynthetic process
B6N31_RS08675	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
B6N31_RS08680	COG0314	molybdopterin synthase activity
B6N31_RS08700	COG0670	Belongs to the BI1 family
B6N31_RS08710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B6N31_RS08715	COG3568	Endonuclease Exonuclease Phosphatase
B6N31_RS08720	COG0842	Transport permease protein
B6N31_RS08725	COG0842	Transport permease protein
B6N31_RS08730	COG1131	(ABC) transporter
B6N31_RS08735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B6N31_RS08740	COG0513	Belongs to the DEAD box helicase family
B6N31_RS08745	COG0697	spore germination
B6N31_RS08760	COG0444	Belongs to the ABC transporter superfamily
B6N31_RS08765	COG4608	Belongs to the ABC transporter superfamily
B6N31_RS08775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B6N31_RS08780	COG0584	glycerophosphoryl diester phosphodiesterase
B6N31_RS08800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B6N31_RS08810	COG2195	Cleaves the N-terminal amino acid of tripeptides
B6N31_RS08815	COG0747	negative chemotaxis
B6N31_RS08820	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B6N31_RS08830	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B6N31_RS08835	COG1686	Belongs to the peptidase S11 family
B6N31_RS08845	COG1349	DNA-binding transcription factor activity
B6N31_RS08860	COG0674	pyruvate-flavodoxin oxidoreductase activity
B6N31_RS08860	COG1013	pyruvate-flavodoxin oxidoreductase activity
B6N31_RS08860	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
B6N31_RS08860	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
B6N31_RS08865	COG0493	'glutamate synthase
B6N31_RS08870	COG1472	Belongs to the glycosyl hydrolase 3 family
B6N31_RS08885	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B6N31_RS08900	COG0671	phosphoesterase, PA-phosphatase related
B6N31_RS08930	COG1126	abc transporter atp-binding protein
B6N31_RS08935	COG0765	amino acid transport
B6N31_RS08940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B6N31_RS08945	COG0783	Belongs to the Dps family
B6N31_RS08955	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
B6N31_RS08960	COG1846	Transcriptional regulator
B6N31_RS08965	COG2807	transmembrane transport
B6N31_RS08985	COG0439	Biotin carboxylase
B6N31_RS08995	COG1984	allophanate hydrolase subunit 2
B6N31_RS09005	COG0071	Belongs to the small heat shock protein (HSP20) family
B6N31_RS09020	COG1136	(ABC) transporter
B6N31_RS09025	COG0577	efflux transmembrane transporter activity
B6N31_RS09025	COG1136	(ABC) transporter
B6N31_RS09045	COG4677	pectinesterase activity
B6N31_RS09050	COG3136	membrane protein required for alginate biosynthesis
B6N31_RS09065	COG0601	transmembrane transport
B6N31_RS09070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B6N31_RS09075	COG0444	Belongs to the ABC transporter superfamily
B6N31_RS09080	COG4608	Belongs to the ABC transporter superfamily
B6N31_RS09105	COG2199	diguanylate cyclase activity
B6N31_RS09105	COG2203	Gaf domain
B6N31_RS09115	COG1393	Belongs to the ArsC family
B6N31_RS09170	COG3082	Protein of unknown function (DUF1414)
B6N31_RS09175	COG3081	Nucleoid-associated protein
B6N31_RS09180	COG3275	phosphorelay sensor kinase activity
B6N31_RS09185	COG3279	Response regulator of the LytR AlgR family
B6N31_RS09190	COG2223	nitrite transmembrane transporter activity
B6N31_RS09195	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B6N31_RS09200	COG1061	Type III restriction enzyme res subunit
B6N31_RS09215	COG2814	Major facilitator Superfamily
B6N31_RS09230	COG4172	Belongs to the ABC transporter superfamily
B6N31_RS09235	COG4239	(ABC) transporter, permease
B6N31_RS09240	COG4174	ABC transporter (Permease)
B6N31_RS09245	COG4166	transmembrane transport
B6N31_RS09250	COG0791	NLP P60 protein
B6N31_RS09255	COG0671	phosphoesterase, PA-phosphatase related
B6N31_RS09260	COG0523	cobalamin synthesis protein
B6N31_RS09265	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B6N31_RS09280	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B6N31_RS09280	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
B6N31_RS09285	COG1105	Belongs to the carbohydrate kinase PfkB family
B6N31_RS09290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B6N31_RS09290	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B6N31_RS09290	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
B6N31_RS09300	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
B6N31_RS09305	COG2855	membrane
B6N31_RS09310	COG0583	DNA-binding transcription factor activity
B6N31_RS09315	COG0833	amino acid
B6N31_RS09325	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B6N31_RS09340	COG0508	dehydrogenase complex catalyzes the overall conversion of
B6N31_RS09350	COG1172	Belongs to the binding-protein-dependent transport system permease family
B6N31_RS09355	COG1129	ABC transporter
B6N31_RS09360	COG0371	Dehydrogenase
B6N31_RS09380	COG0583	DNA-binding transcription factor activity
B6N31_RS09385	COG0840	transmembrane signaling receptor activity
B6N31_RS09395	COG0840	transmembrane signaling receptor activity
B6N31_RS09400	COG0840	transmembrane signaling receptor activity
B6N31_RS09405	COG0840	transmembrane signaling receptor activity
B6N31_RS09410	COG0302	gtp cyclohydrolase
B6N31_RS09415	COG2311	Membrane
B6N31_RS09420	COG2949	membrane
B6N31_RS09425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B6N31_RS09430	COG2133	pyrroloquinoline quinone binding
B6N31_RS09435	COG0625	glutathione transferase activity
B6N31_RS09440	COG1464	Belongs to the NlpA lipoprotein family
B6N31_RS09445	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B6N31_RS09450	COG2011	ABC-type metal ion transport system permease component
B6N31_RS09455	COG2267	carboxylic ester hydrolase activity
B6N31_RS09460	COG1686	Belongs to the peptidase S11 family
B6N31_RS09465	COG1349	DNA-binding transcription factor activity
B6N31_RS09470	COG2985	domain, Protein
B6N31_RS09470	COG0569	domain protein
B6N31_RS09495	COG0189	ligase activity
B6N31_RS09505	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B6N31_RS09510	COG3842	ATPase activity
B6N31_RS09515	COG1176	ABC-type spermidine putrescine transport system, permease component I
B6N31_RS09520	COG1177	transmembrane transport
B6N31_RS09530	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B6N31_RS09540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B6N31_RS09545	COG4160	amino acid transport
B6N31_RS09550	COG4215	(ABC) transporter
B6N31_RS09555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B6N31_RS09560	COG1126	abc transporter atp-binding protein
B6N31_RS09565	COG0393	Putative heavy-metal-binding
B6N31_RS09570	COG3023	N-Acetylmuramoyl-L-alanine amidase
B6N31_RS09575	COG0702	epimerase
B6N31_RS09580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B6N31_RS09585	COG1151	hydroxylamine reductase activity
B6N31_RS09590	COG3593	DNA synthesis involved in DNA repair
B6N31_RS09595	COG1278	Cold shock
B6N31_RS09600	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
B6N31_RS09605	COG0542	response to heat
B6N31_RS09610	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B6N31_RS09615	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
B6N31_RS09620	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
B6N31_RS09625	COG4988	ABC transporter
B6N31_RS09630	COG0492	ferredoxin-NADP+ reductase activity
B6N31_RS09640	COG1674	ftsk spoiiie
B6N31_RS09640	COG3107	peptidoglycan biosynthetic process
B6N31_RS09645	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
B6N31_RS09650	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B6N31_RS09655	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B6N31_RS09680	COG0583	DNA-binding transcription factor activity
B6N31_RS09685	COG2814	Major facilitator Superfamily
B6N31_RS09695	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B6N31_RS09700	COG1882	Formate acetyltransferase
B6N31_RS09705	COG2116	formate transmembrane transporter activity
B6N31_RS09710	COG1944	ATP diphosphatase activity
B6N31_RS09715	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
B6N31_RS09725	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B6N31_RS09730	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
B6N31_RS09735	COG0539	negative regulation of cytoplasmic translation
B6N31_RS09740	COG0776	regulation of translation
B6N31_RS09755	COG0140	phosphoribosyl-ATP diphosphatase activity
B6N31_RS09755	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B6N31_RS09760	COG0107	imidazoleglycerol-phosphate synthase activity
B6N31_RS09765	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B6N31_RS09770	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B6N31_RS09775	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
B6N31_RS09775	COG0131	Imidazoleglycerol-phosphate dehydratase
B6N31_RS09780	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B6N31_RS09785	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B6N31_RS09790	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B6N31_RS09800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B6N31_RS09805	COG0840	transmembrane signaling receptor activity
B6N31_RS09820	COG3493	citrate carrier protein
B6N31_RS09825	COG0179	Fumarylacetoacetate (FAA) hydrolase
B6N31_RS09830	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
B6N31_RS09835	COG3052	prosthetic group binding
B6N31_RS09850	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
B6N31_RS09850	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
B6N31_RS09855	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
B6N31_RS09860	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
B6N31_RS09870	COG0531	amino acid
B6N31_RS09880	COG2925	Exonuclease
B6N31_RS09885	COG2926	Belongs to the UPF0265 family
B6N31_RS09895	COG0658	competence protein
B6N31_RS09895	COG2333	competence protein COMEC
B6N31_RS09900	COG1132	(ABC) transporter
B6N31_RS09905	COG1663	tetraacyldisaccharide 4'-kinase activity
B6N31_RS09910	COG2835	tetraacyldisaccharide 4'-kinase activity
B6N31_RS09915	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
B6N31_RS09925	COG3173	Aminoglycoside phosphotransferase
B6N31_RS09930	COG1434	Gram-negative-bacterium-type cell wall biogenesis
B6N31_RS09935	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B6N31_RS09940	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
B6N31_RS09945	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
B6N31_RS09950	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
B6N31_RS09960	COG2918	glutathione biosynthetic process
B6N31_RS09960	COG0189	ligase activity
B6N31_RS09965	COG2132	Multicopper oxidase
B6N31_RS09970	COG1733	regulation of RNA biosynthetic process
B6N31_RS09980	COG0494	nUDIX hydrolase
B6N31_RS09990	COG0625	glutathione transferase activity
B6N31_RS10000	COG1349	DNA-binding transcription factor activity
B6N31_RS10025	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B6N31_RS10030	COG3381	protein complex oligomerization
B6N31_RS10040	COG2999	glutathione oxidoreductase activity
B6N31_RS10045	COG0477	Major facilitator Superfamily
B6N31_RS10050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B6N31_RS10055	COG3132	Protein of unknown function, DUF480
B6N31_RS10155	COG0018	arginyl-trna synthetase
B6N31_RS10160	COG3102	Protein conserved in bacteria
B6N31_RS10165	COG3142	Participates in the control of copper homeostasis
B6N31_RS10175	COG0500	methyltransferase
B6N31_RS10180	COG2226	methyltransferase
B6N31_RS10185	COG3788	relative of glutathione S-transferase, MAPEG superfamily
B6N31_RS10190	COG1801	Protein of unknown function DUF72
B6N31_RS10195	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B6N31_RS10200	COG0494	nUDIX hydrolase
B6N31_RS10205	COG0217	transcriptional regulatory protein
B6N31_RS10215	COG2390	Transcriptional regulator
B6N31_RS10230	COG3395	kinase activity
B6N31_RS10245	COG0698	ribose 5-phosphate isomerase
B6N31_RS10250	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B6N31_RS10255	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B6N31_RS10260	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
B6N31_RS10265	COG0632	four-way junction helicase activity
B6N31_RS10270	COG2255	four-way junction helicase activity
B6N31_RS10275	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B6N31_RS10280	COG1121	(ABC) transporter
B6N31_RS10285	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
B6N31_RS10290	COG0739	heme binding
B6N31_RS10295	COG1560	Kdo2-lipid A biosynthetic process
B6N31_RS10310	COG0469	pyruvate kinase activity
B6N31_RS10315	COG1737	Transcriptional regulator
B6N31_RS10320	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
B6N31_RS10325	COG0800	Aldolase
B6N31_RS10330	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
B6N31_RS10335	COG1770	oligopeptidase
B6N31_RS10350	COG1276	copper resistance
B6N31_RS10355	COG1528	Iron-storage protein
B6N31_RS10365	COG2204	response regulator
B6N31_RS10405	COG2261	transglycosylase associated protein
B6N31_RS10425	COG0444	Belongs to the ABC transporter superfamily
B6N31_RS10430	COG2718	Belongs to the UPF0229 family
B6N31_RS10435	COG2766	serine protein kinase
B6N31_RS10440	COG3713	MltA-interacting MipA family protein
B6N31_RS10445	COG0656	L-ascorbic acid biosynthetic process
B6N31_RS10460	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B6N31_RS10465	COG3139	Protein of unknown function (DUF1315)
B6N31_RS10470	COG1335	isochorismatase
B6N31_RS10475	COG0252	asparaginase activity
B6N31_RS10480	COG0616	signal peptide processing
B6N31_RS10490	COG0778	Nitroreductase
B6N31_RS10510	COG2860	membrane
B6N31_RS10520	COG0788	formyltetrahydrofolate deformylase activity
B6N31_RS10525	COG3012	SEC-C Motif Domain Protein
B6N31_RS10530	COG1752	Esterase of the alpha-beta hydrolase superfamily
B6N31_RS10535	COG0745	RESPONSE REGULATOR receiver
B6N31_RS10540	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B6N31_RS10550	COG1435	thymidine kinase activity
B6N31_RS10555	COG1012	belongs to the aldehyde dehydrogenase family
B6N31_RS10555	COG1454	alcohol dehydrogenase
B6N31_RS10565	COG2095	MarC family integral membrane protein
B6N31_RS10585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B6N31_RS10590	COG0444	Belongs to the ABC transporter superfamily
B6N31_RS10605	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B6N31_RS10610	COG0840	transmembrane signaling receptor activity
B6N31_RS10615	COG2350	Protein conserved in bacteria
B6N31_RS10630	COG2917	probably involved in intracellular septation
B6N31_RS10640	COG0727	PFAM Uncharacterised protein family (UPF0153)
B6N31_RS10645	COG3047	cAMP biosynthetic process
B6N31_RS10650	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
B6N31_RS10655	COG0159	tryptophan synthase activity
B6N31_RS10660	COG0133	tryptophan synthase activity
B6N31_RS10670	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B6N31_RS10675	COG0512	Glutamine amidotransferase of anthranilate synthase
B6N31_RS10685	COG0613	PHP domain protein
B6N31_RS10690	COG0009	L-threonylcarbamoyladenylate synthase
B6N31_RS10695	COG1187	pseudouridine synthase activity
B6N31_RS10700	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
B6N31_RS10705	COG1028	Short-chain dehydrogenase reductase Sdr
B6N31_RS10710	COG0616	signal peptide processing
B6N31_RS10735	COG0583	DNA-binding transcription factor activity
B6N31_RS10740	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B6N31_RS10750	COG4659	FMN binding
B6N31_RS10755	COG4658	electron transport chain
B6N31_RS10760	COG4656	Part of a membrane complex involved in electron transport
B6N31_RS10765	COG2878	Part of a membrane complex involved in electron transport
B6N31_RS10770	COG4657	Part of a membrane complex involved in electron transport
B6N31_RS10780	COG2160	L-arabinose isomerase activity
B6N31_RS10785	COG1069	ribulokinase activity
B6N31_RS10790	COG1879	ABC-type sugar transport system periplasmic component
B6N31_RS10795	COG1129	ABC transporter
B6N31_RS10800	COG1172	Belongs to the binding-protein-dependent transport system permease family
B6N31_RS10810	COG0673	inositol 2-dehydrogenase activity
B6N31_RS10815	COG0385	Bile acid
B6N31_RS10825	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B6N31_RS10830	COG5339	Protein conserved in bacteria
B6N31_RS10835	COG1482	cell wall glycoprotein biosynthetic process
B6N31_RS10840	COG0114	fumarate hydratase activity
B6N31_RS10850	COG2814	Major facilitator Superfamily
B6N31_RS10855	COG0583	DNA-binding transcription factor activity
B6N31_RS10860	COG1940	carbohydrate kinase activity
B6N31_RS10865	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B6N31_RS10880	COG4221	oxidoreductase activity
B6N31_RS10885	COG2226	methyltransferase
B6N31_RS10890	COG1215	transferase activity, transferring glycosyl groups
B6N31_RS10915	COG4305	rare lipoprotein A
B6N31_RS10930	COG2995	paraquat-inducible protein a
B6N31_RS10935	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B6N31_RS10935	COG3008	intermembrane lipid transfer
B6N31_RS10960	COG3158	transport of potassium into the cell
B6N31_RS11005	COG0702	epimerase
B6N31_RS11035	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
B6N31_RS11040	COG0483	inositol monophosphate 1-phosphatase activity
B6N31_RS11045	COG0584	glycerophosphoryl diester phosphodiesterase
B6N31_RS11065	COG3842	ATPase activity
B6N31_RS11080	COG3479	Phenolic acid decarboxylase
B6N31_RS11090	COG0840	transmembrane signaling receptor activity
B6N31_RS11110	COG0840	transmembrane signaling receptor activity
B6N31_RS11120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B6N31_RS11130	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
B6N31_RS11135	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
B6N31_RS11145	COG2877	3-deoxy-8-phosphooctulonate synthase activity
B6N31_RS11155	COG2890	protein-(glutamine-N5) methyltransferase activity
B6N31_RS11160	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B6N31_RS11165	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
B6N31_RS11170	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
B6N31_RS11175	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
B6N31_RS11180	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B6N31_RS11190	COG0583	DNA-binding transcription factor activity
B6N31_RS11200	COG0193	aminoacyl-tRNA hydrolase activity
B6N31_RS11205	COG0012	GTP binding
B6N31_RS11240	COG0667	Aldo Keto reductase
B6N31_RS11265	COG0513	Belongs to the DEAD box helicase family
B6N31_RS11290	COG3706	GGDEF domain
B6N31_RS11295	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B6N31_RS11300	COG1074	ATP-dependent DNA helicase activity
B6N31_RS11305	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
B6N31_RS11385	COG3210	domain, Protein
B6N31_RS11415	COG3210	domain, Protein
B6N31_RS11420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B6N31_RS11425	COG2719	SpoVR family
B6N31_RS11430	COG2186	Transcriptional regulator
B6N31_RS11435	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
B6N31_RS11445	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
B6N31_RS11450	COG2983	Belongs to the UPF0260 family
B6N31_RS11455	COG0179	Fumarylacetoacetate (FAA) hydrolase
B6N31_RS11465	COG0850	regulation of cytokinetic process
B6N31_RS11470	COG2894	cell division
B6N31_RS11475	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
B6N31_RS11480	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
B6N31_RS11485	COG0318	PFAM AMP-dependent synthetase and ligase
B6N31_RS11490	COG3065	identical protein binding
B6N31_RS11500	COG1199	ATP-dependent helicase activity
B6N31_RS11505	COG0251	oxidation-reduction process
B6N31_RS11520	COG0494	nUDIX hydrolase
B6N31_RS11525	COG1760	l-serine dehydratase
B6N31_RS11530	COG0840	transmembrane signaling receptor activity
B6N31_RS11535	COG1253	flavin adenine dinucleotide binding
B6N31_RS11540	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B6N31_RS11540	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B6N31_RS11545	COG3715	PTS system
B6N31_RS11550	COG3716	PTS system mannose fructose sorbose family IID component
B6N31_RS11560	COG1971	Probably functions as a manganese efflux pump
B6N31_RS11565	COG2226	methyltransferase
B6N31_RS11580	COG3001	Fructosamine kinase
B6N31_RS11590	COG1917	Cupin 2, conserved barrel domain protein
B6N31_RS11595	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
B6N31_RS11600	COG1028	Short-chain dehydrogenase reductase Sdr
B6N31_RS11610	COG1175	transmembrane transport
B6N31_RS11615	COG0395	ABC-type sugar transport system, permease component
B6N31_RS11620	COG3842	ATPase activity
B6N31_RS11630	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
B6N31_RS11635	COG0657	acetylesterase activity
B6N31_RS11635	COG2755	lipolytic protein G-D-S-L family
B6N31_RS11640	COG1988	membrane-bound metal-dependent
B6N31_RS11645	COG1823	symporter activity
B6N31_RS11650	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B6N31_RS11655	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B6N31_RS11670	COG0776	regulation of translation
B6N31_RS11675	COG0072	phenylalanine-tRNA ligase activity
B6N31_RS11675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B6N31_RS11680	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B6N31_RS11695	COG0291	Belongs to the bacterial ribosomal protein bL35 family
B6N31_RS11700	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B6N31_RS11705	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B6N31_RS11720	COG0823	Involved in the tonB-independent uptake of proteins
B6N31_RS11725	COG0501	Belongs to the peptidase M48B family
B6N31_RS11735	COG0538	isocitrate dehydrogenase activity
B6N31_RS11750	COG0482	sulfurtransferase activity
B6N31_RS11755	COG2915	High frequency lysogenization protein hflD homolog
B6N31_RS11760	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B6N31_RS11775	COG2850	peptidyl-arginine hydroxylation
B6N31_RS11780	COG2195	Cleaves the N-terminal amino acid of tripeptides
B6N31_RS11830	COG3609	addiction module antidote protein, CC2985 family
B6N31_RS11835	COG4974	Belongs to the 'phage' integrase family
B6N31_RS11840	COG0358	DNA primase activity
B6N31_RS11855	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
B6N31_RS11875	COG3609	addiction module antidote protein, CC2985 family
B6N31_RS11880	COG4974	Belongs to the 'phage' integrase family
B6N31_RS11885	COG0358	DNA primase activity
B6N31_RS11900	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
B6N31_RS11915	COG2831	hemolysin activation secretion protein
B6N31_RS11965	COG2951	lytic endotransglycosylase activity
B6N31_RS12000	COG2197	response regulator
B6N31_RS12005	COG4585	Histidine kinase
B6N31_RS12055	COG4794	Type iii secretion
B6N31_RS12065	COG4792	protein secretion
B6N31_RS12075	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
B6N31_RS12080	COG0840	transmembrane signaling receptor activity
B6N31_RS12085	COG0840	transmembrane signaling receptor activity
B6N31_RS12105	COG0626	cystathionine gamma-synthase activity
B6N31_RS12110	COG0765	amino acid transport
B6N31_RS12115	COG0765	amino acid transport
B6N31_RS12120	COG1126	abc transporter atp-binding protein
B6N31_RS12130	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B6N31_RS12140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B6N31_RS12145	COG1473	amidohydrolase
B6N31_RS12150	COG1028	Short-chain dehydrogenase reductase Sdr
B6N31_RS12155	COG4172	Belongs to the ABC transporter superfamily
B6N31_RS12160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B6N31_RS12190	COG0747	negative chemotaxis
B6N31_RS12195	COG4608	Belongs to the ABC transporter superfamily
B6N31_RS12200	COG0444	Belongs to the ABC transporter superfamily
B6N31_RS12210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B6N31_RS12215	COG0601	transmembrane transport
B6N31_RS12225	COG2072	flavoprotein involved in K transport
B6N31_RS12230	COG0583	DNA-binding transcription factor activity
B6N31_RS12240	COG0561	phosphatase activity
B6N31_RS12245	COG2223	nitrite transmembrane transporter activity
B6N31_RS12250	COG0483	inositol monophosphate 1-phosphatase activity
B6N31_RS12255	COG1349	DNA-binding transcription factor activity
B6N31_RS12260	COG4774	siderophore transport
B6N31_RS12275	COG1176	ABC-type spermidine putrescine transport system, permease component I
B6N31_RS12285	COG1012	belongs to the aldehyde dehydrogenase family
B6N31_RS12290	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B6N31_RS12300	COG3842	ATPase activity
B6N31_RS12335	COG0667	Aldo Keto reductase
B6N31_RS12355	COG0583	DNA-binding transcription factor activity
B6N31_RS12375	COG0656	L-ascorbic acid biosynthetic process
B6N31_RS12395	COG1454	alcohol dehydrogenase
B6N31_RS12400	COG0494	nUDIX hydrolase
B6N31_RS12405	COG2181	nitrate reductase activity
B6N31_RS12410	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
B6N31_RS12415	COG1140	nitrate reductase beta subunit
B6N31_RS12420	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
B6N31_RS12425	COG2223	nitrite transmembrane transporter activity
B6N31_RS12430	COG3850	Histidine kinase
B6N31_RS12435	COG2197	response regulator
B6N31_RS12455	COG0793	Belongs to the peptidase S41A family
B6N31_RS12460	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
B6N31_RS12465	COG1956	GAF domain-containing protein
B6N31_RS12470	COG2995	paraquat-inducible protein a
B6N31_RS12475	COG3008	intermembrane lipid transfer
B6N31_RS12480	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
B6N31_RS12480	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B6N31_RS12490	COG0840	transmembrane signaling receptor activity
B6N31_RS12515	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B6N31_RS12595	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B6N31_RS12660	COG0840	transmembrane signaling receptor activity
B6N31_RS12670	COG0840	transmembrane signaling receptor activity
B6N31_RS12680	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B6N31_RS12685	COG0038	chloride channel
B6N31_RS12695	COG4608	Belongs to the ABC transporter superfamily
B6N31_RS12700	COG0444	Belongs to the ABC transporter superfamily
B6N31_RS12705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B6N31_RS12710	COG0601	transmembrane transport
B6N31_RS12715	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
B6N31_RS12720	COG0387	Pfam Sodium calcium exchanger
B6N31_RS12725	COG0659	secondary active sulfate transmembrane transporter activity
B6N31_RS12735	COG0745	RESPONSE REGULATOR receiver
B6N31_RS12740	COG2205	protein histidine kinase activity
B6N31_RS12750	COG3591	Belongs to the peptidase S1B family
B6N31_RS12755	COG1643	Atp-dependent helicase
B6N31_RS12760	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B6N31_RS12770	COG2911	Protein conserved in bacteria
B6N31_RS12775	COG0840	transmembrane signaling receptor activity
B6N31_RS12780	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B6N31_RS12790	COG0840	transmembrane signaling receptor activity
B6N31_RS12815	COG0037	tRNA processing
B6N31_RS12820	COG0598	Magnesium transport protein CorA
B6N31_RS12825	COG4166	transmembrane transport
B6N31_RS12830	COG2866	Carboxypeptidase
B6N31_RS12835	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
B6N31_RS12840	COG0477	Major facilitator Superfamily
B6N31_RS12855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B6N31_RS12880	COG2271	Major facilitator Superfamily
B6N31_RS12885	COG3768	UPF0283 membrane protein
B6N31_RS12890	COG3106	COG3106 Predicted ATPase
B6N31_RS12895	COG1983	PspC domain protein
B6N31_RS12905	COG1842	Phage shock protein A
B6N31_RS12910	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B6N31_RS12930	COG4166	transmembrane transport
B6N31_RS12945	COG4172	Belongs to the ABC transporter superfamily
B6N31_RS12960	COG0583	DNA-binding transcription factor activity
B6N31_RS12965	COG0243	molybdopterin cofactor binding
B6N31_RS12980	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
B6N31_RS12985	COG4989	oxidoreductase activity
B6N31_RS12990	COG1966	Carbon starvation protein
B6N31_RS13010	COG0023	Translation Initiation Factor
B6N31_RS13020	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
B6N31_RS13025	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
B6N31_RS13030	COG0671	phosphoesterase, PA-phosphatase related
B6N31_RS13050	COG0625	glutathione transferase activity
B6N31_RS13055	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
B6N31_RS13065	COG0259	pyridoxamine-phosphate oxidase activity
B6N31_RS13070	COG3895	Periplasmic Protein
B6N31_RS13075	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
B6N31_RS13090	COG3313	Fe-S protein
B6N31_RS13095	COG0346	lactoylglutathione lyase activity
B6N31_RS13100	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B6N31_RS13105	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
B6N31_RS13110	COG0791	NLP P60 protein
B6N31_RS13120	COG1609	Transcriptional regulator
B6N31_RS13125	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B6N31_RS13130	COG0307	riboflavin synthase, alpha
B6N31_RS13135	COG0534	Mate efflux family protein
B6N31_RS13160	COG1794	racemase activity, acting on amino acids and derivatives
B6N31_RS13180	COG0534	Mate efflux family protein
B6N31_RS13195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B6N31_RS13220	COG0156	8-amino-7-oxononanoate synthase activity
B6N31_RS13230	COG4221	oxidoreductase activity
B6N31_RS13230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B6N31_RS13230	COG3321	synthase
B6N31_RS13230	COG1028	Short-chain dehydrogenase reductase Sdr
B6N31_RS13240	COG1403	HNH endonuclease
B6N31_RS13250	COG2382	esterase
B6N31_RS13310	COG1902	pentaerythritol trinitrate reductase activity
B6N31_RS13315	COG0583	DNA-binding transcription factor activity
B6N31_RS13330	COG4238	major outer membrane lipoprotein
B6N31_RS13335	COG1388	LysM domain
B6N31_RS13335	COG1376	ErfK ybiS ycfS ynhG family protein
B6N31_RS13340	COG2166	iron-sulfur cluster assembly
B6N31_RS13345	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B6N31_RS13350	COG0719	Fe-S assembly protein
B6N31_RS13355	COG0396	ATPase activity
B6N31_RS13360	COG0719	Fe-S assembly protein
B6N31_RS13365	COG0316	Belongs to the HesB IscA family
B6N31_RS13375	COG2050	protein possibly involved in aromatic compounds catabolism
B6N31_RS13380	COG0247	lactate metabolic process
B6N31_RS13380	COG0277	FAD linked oxidase domain protein
B6N31_RS13385	COG0628	permease
B6N31_RS13395	COG0574	Belongs to the PEP-utilizing enzyme family
B6N31_RS13395	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B6N31_RS13400	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
B6N31_RS13405	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B6N31_RS13410	COG3130	regulation of translation
B6N31_RS13415	COG3009	Protein conserved in bacteria
B6N31_RS13420	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B6N31_RS13420	COG3008	intermembrane lipid transfer
B6N31_RS13425	COG2995	paraquat-inducible protein a
B6N31_RS13430	COG0488	(ABC) transporter
B6N31_RS13435	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B6N31_RS13435	COG0116	Belongs to the methyltransferase superfamily
B6N31_RS13440	COG3217	Mosc domain protein beta barrel domain protein
B6N31_RS13440	COG0633	Ferredoxin
B6N31_RS13450	COG0167	dihydroorotate dehydrogenase activity
B6N31_RS13455	COG0431	NADPH-dependent FMN reductase
B6N31_RS13460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B6N31_RS13465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B6N31_RS13470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B6N31_RS13475	COG1116	anion transmembrane transporter activity
B6N31_RS13480	COG0308	aminopeptidase N
B6N31_RS13485	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
B6N31_RS13490	COG0017	Asparaginyl-tRNA synthetase
B6N31_RS13505	COG1448	Aminotransferase
B6N31_RS13510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B6N31_RS13515	COG3108	Peptidase M15
B6N31_RS13520	COG2989	Protein conserved in bacteria
B6N31_RS13525	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
B6N31_RS13535	COG0095	Lipoate-protein ligase
B6N31_RS13540	COG0791	NLP P60 protein
B6N31_RS13545	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
B6N31_RS13550	COG0386	Belongs to the glutathione peroxidase family
B6N31_RS13555	COG4139	cobalamin transport
B6N31_RS13575	COG4591	ABC-type transport system involved in lipoprotein release permease component
B6N31_RS13580	COG1136	(ABC) transporter
B6N31_RS13585	COG4591	ABC-type transport system involved in lipoprotein release permease component
B6N31_RS13590	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B6N31_RS13595	COG2200	EAL domain
B6N31_RS13600	COG0443	Heat shock 70 kDa protein
B6N31_RS13615	COG2271	Major facilitator Superfamily
B6N31_RS13620	COG1609	Transcriptional regulator
B6N31_RS13625	COG3134	Outer membrane lipoprotein
B6N31_RS13630	COG1252	NADH dehydrogenase
B6N31_RS13640	COG1472	Belongs to the glycosyl hydrolase 3 family
B6N31_RS13650	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
B6N31_RS13655	COG5633	Lipoprotein
B6N31_RS13660	COG0537	adenosine 5'-monophosphoramidase activity
B6N31_RS13665	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B6N31_RS13670	COG1263	PTS System
B6N31_RS13670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B6N31_RS13675	COG0084	hydrolase, TatD family'
B6N31_RS13680	COG0470	DNA polymerase III
B6N31_RS13685	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B6N31_RS13690	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B6N31_RS13695	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B6N31_RS13700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B6N31_RS13705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B6N31_RS13710	COG1028	Short-chain dehydrogenase reductase Sdr
B6N31_RS13720	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B6N31_RS13725	COG0416	fatty acid biosynthetic process
B6N31_RS13730	COG0333	Belongs to the bacterial ribosomal protein bL32 family
B6N31_RS13735	COG1399	metal-binding, possibly nucleic acid-binding protein
B6N31_RS13740	COG0424	maF-like protein
B6N31_RS13745	COG0564	pseudouridine synthase activity
B6N31_RS13755	COG1530	ribonuclease E activity
B6N31_RS13765	COG0418	dihydroorotase activity
B6N31_RS13780	COG3038	cytochrome b561
B6N31_RS13785	COG2353	YceI-like domain
B6N31_RS13790	COG1054	Belongs to the UPF0176 family
B6N31_RS13800	COG1560	Kdo2-lipid A biosynthetic process
B6N31_RS13805	COG2814	Major facilitator Superfamily
B6N31_RS13810	COG2943	transferase activity, transferring hexosyl groups
B6N31_RS13815	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
B6N31_RS13830	COG0840	transmembrane signaling receptor activity
B6N31_RS13850	COG1067	ATP-dependent peptidase activity
B6N31_RS13855	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B6N31_RS13865	COG1012	belongs to the aldehyde dehydrogenase family
B6N31_RS13885	COG0840	transmembrane signaling receptor activity
B6N31_RS13900	COG1702	phosphate starvation-inducible protein PhoH
B6N31_RS13915	COG1191	sigma factor activity
B6N31_RS13925	COG0673	inositol 2-dehydrogenase activity
B6N31_RS13940	COG0500	methyltransferase
B6N31_RS13950	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
B6N31_RS13965	COG1677	Flagellar hook-basal body complex protein FliE
B6N31_RS13980	COG1317	bacterial-type flagellum organization
B6N31_RS13985	COG1157	protein secretion by the type III secretion system
B6N31_RS13995	COG3144	bacterial-type flagellum assembly
B6N31_RS14000	COG1580	Controls the rotational direction of flagella during chemotaxis
B6N31_RS14010	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B6N31_RS14035	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B6N31_RS14040	COG1256	bacterial-type flagellum assembly
B6N31_RS14050	COG1706	bacterial-type flagellum-dependent cell motility
B6N31_RS14055	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
B6N31_RS14065	COG4787	bacterial-type flagellum-dependent cell motility
B6N31_RS14075	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
B6N31_RS14080	COG1558	bacterial-type flagellum-dependent cell motility
B6N31_RS14085	COG1815	bacterial-type flagellum-dependent cell motility
B6N31_RS14095	COG2747	anti-sigma28 factor FlgM
B6N31_RS14110	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B6N31_RS14115	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B6N31_RS14120	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
B6N31_RS14125	COG0745	RESPONSE REGULATOR receiver
B6N31_RS14130	COG2201	protein-glutamate methylesterase activity
B6N31_RS14135	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B6N31_RS14140	COG0840	transmembrane signaling receptor activity
B6N31_RS14145	COG0835	chemotaxis
B6N31_RS14150	COG2198	Histidine kinase
B6N31_RS14150	COG0643	Histidine kinase
B6N31_RS14155	COG1360	Flagellar Motor Protein
B6N31_RS14175	COG1979	alcohol dehydrogenase
B6N31_RS14180	COG0840	transmembrane signaling receptor activity
B6N31_RS14200	COG0534	Mate efflux family protein
B6N31_RS14210	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
B6N31_RS14215	COG4733	cellulase activity
B6N31_RS14255	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B6N31_RS14260	COG0322	excinuclease ABC activity
B6N31_RS14265	COG2197	response regulator
B6N31_RS14280	COG1113	amino acid transport
B6N31_RS14295	COG1819	glycosyl
B6N31_RS14300	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B6N31_RS14310	COG0840	transmembrane signaling receptor activity
B6N31_RS14320	COG1619	proteins homologs of microcin C7 resistance protein MccF
B6N31_RS14325	COG0583	DNA-binding transcription factor activity
B6N31_RS14330	COG0436	Aminotransferase
B6N31_RS14360	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B6N31_RS14360	COG1648	precorrin-2 dehydrogenase activity
B6N31_RS14365	COG0243	molybdopterin cofactor binding
B6N31_RS14370	COG2146	nitrite reductase [NAD(P)H] activity
B6N31_RS14370	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B6N31_RS14375	COG1116	anion transmembrane transporter activity
B6N31_RS14385	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B6N31_RS14390	COG3707	response regulator
B6N31_RS14400	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B6N31_RS14405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B6N31_RS14415	COG2814	Major facilitator Superfamily
B6N31_RS14420	COG0657	acetylesterase activity
B6N31_RS14425	COG3058	Necessary for formate dehydrogenase activity
B6N31_RS14430	COG2271	Major facilitator Superfamily
B6N31_RS14445	COG2864	formate dehydrogenase
B6N31_RS14450	COG0437	4 iron, 4 sulfur cluster binding
B6N31_RS14455	COG0243	molybdopterin cofactor binding
B6N31_RS14455	COG3383	formate dehydrogenase (NAD+) activity
B6N31_RS14460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B6N31_RS14465	COG0519	Catalyzes the synthesis of GMP from XMP
B6N31_RS14465	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B6N31_RS14475	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
B6N31_RS14485	COG0309	Hydrogenase expression formation protein (HypE)
B6N31_RS14490	COG0409	Hydrogenase expression formation protein
B6N31_RS14495	COG0298	carbon dioxide binding
B6N31_RS14500	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
B6N31_RS14510	COG1773	rubredoxin
B6N31_RS14515	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
B6N31_RS14520	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
B6N31_RS14525	COG5557	Pfam Polysulphide reductase, NrfD
B6N31_RS14530	COG0437	4 iron, 4 sulfur cluster binding
B6N31_RS14535	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
B6N31_RS14540	COG0488	(ABC) transporter
B6N31_RS14545	COG0384	phenazine biosynthesis protein PhzF
B6N31_RS14550	COG2132	Multicopper oxidase
B6N31_RS14555	COG1007	ATP synthesis coupled electron transport
B6N31_RS14560	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B6N31_RS14565	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B6N31_RS14570	COG0713	ATP synthesis coupled electron transport
B6N31_RS14575	COG0839	Belongs to the complex I subunit 6 family
B6N31_RS14580	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B6N31_RS14585	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
B6N31_RS14595	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
B6N31_RS14605	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B6N31_RS14605	COG0649	NAD binding
B6N31_RS14615	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B6N31_RS14620	COG0583	DNA-binding transcription factor activity
B6N31_RS14625	COG0436	Aminotransferase
B6N31_RS14630	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
B6N31_RS14635	COG0471	metal ion transport
B6N31_RS14635	COG0490	domain, Protein
B6N31_RS14640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B6N31_RS14645	COG3013	Belongs to the UPF0304 family
B6N31_RS14650	COG3092	negative regulation of chromosome organization
B6N31_RS14660	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B6N31_RS14665	COG0280	phosphate acetyltransferase
B6N31_RS14665	COG0857	belongs to the CobB CobQ family
B6N31_RS14670	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
B6N31_RS14675	COG0622	Phosphoesterase
B6N31_RS14680	COG0625	glutathione transferase activity
B6N31_RS14685	COG1090	epimerase
B6N31_RS14700	COG4215	(ABC) transporter
B6N31_RS14705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B6N31_RS14710	COG0163	prenyltransferase activity
B6N31_RS14715	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
B6N31_RS14720	COG1286	toxin biosynthetic process
B6N31_RS14725	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
B6N31_RS14730	COG0285	dihydrofolate synthase activity
B6N31_RS14735	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B6N31_RS14745	COG0586	Pfam SNARE associated Golgi protein
B6N31_RS14750	COG0101	tRNA pseudouridine synthase activity
B6N31_RS14755	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B6N31_RS14760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B6N31_RS14770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B6N31_RS14775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B6N31_RS14775	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
B6N31_RS14795	COG1764	response to oxidative stress
B6N31_RS14825	COG3101	peptidyl-lysine hydroxylation
B6N31_RS14830	COG0730	response to heat
B6N31_RS14835	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
B6N31_RS14840	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B6N31_RS14845	COG2890	protein-(glutamine-N5) methyltransferase activity
B6N31_RS14850	COG2840	Smr protein MutS2
B6N31_RS14855	COG2062	phosphohistidine phosphatase, SixA
B6N31_RS14860	COG1250	3-hydroxyacyl-CoA dehydrogenase
B6N31_RS14860	COG1024	Enoyl-CoA hydratase
B6N31_RS14865	COG0183	Belongs to the thiolase family
B6N31_RS14870	COG3691	Protein conserved in bacteria
B6N31_RS14880	COG2067	long-chain fatty acid transport protein
B6N31_RS14885	COG0579	oxidoreductase
B6N31_RS14900	COG0582	viral genome integration into host DNA
B6N31_RS14970	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
B6N31_RS14985	COG4592	Periplasmic binding protein
B6N31_RS14995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B6N31_RS15000	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B6N31_RS15005	COG1120	ATPase activity
B6N31_RS15020	COG2382	esterase
B6N31_RS15025	COG4774	siderophore transport
B6N31_RS15030	COG1169	isochorismate synthase
B6N31_RS15035	COG1021	2,3-dihydroxybenzoate-AMP ligase
B6N31_RS15040	COG3433	isochorismatase activity
B6N31_RS15040	COG1535	isochorismatase
B6N31_RS15045	COG1028	Short-chain dehydrogenase reductase Sdr
B6N31_RS15050	COG2050	protein possibly involved in aromatic compounds catabolism
B6N31_RS15060	COG1902	pentaerythritol trinitrate reductase activity
B6N31_RS15070	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B6N31_RS15125	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B6N31_RS15130	COG1450	Type ii and iii secretion system protein
B6N31_RS15135	COG3031	protein transport across the cell outer membrane
B6N31_RS15150	COG3266	domain, Protein
B6N31_RS15160	COG0436	Aminotransferase
B6N31_RS15165	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B6N31_RS15170	COG3264	Mechanosensitive ion channel
B6N31_RS15170	COG1511	domain protein
B6N31_RS15180	COG0583	DNA-binding transcription factor activity
B6N31_RS15200	COG2850	peptidyl-arginine hydroxylation
B6N31_RS15225	COG0583	DNA-binding transcription factor activity
B6N31_RS15240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B6N31_RS15240	COG1263	PTS System
B6N31_RS15245	COG1874	Beta-galactosidase
B6N31_RS15255	COG3833	ABC-type maltose transport systems, permease component
B6N31_RS15260	COG1175	transmembrane transport
B6N31_RS15265	COG2182	Extracellular solute-binding protein
B6N31_RS15275	COG1473	amidohydrolase
B6N31_RS15290	COG5297	Belongs to the glycosyl hydrolase family 6
B6N31_RS15305	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
B6N31_RS15310	COG2986	histidine ammonia-lyase
B6N31_RS15360	COG3290	protein histidine kinase activity
B6N31_RS15365	COG4565	transcriptional regulatory protein
B6N31_RS15370	COG2986	histidine ammonia-lyase
B6N31_RS15400	COG0402	S-adenosylhomocysteine deaminase activity
B6N31_RS15415	COG0840	transmembrane signaling receptor activity
B6N31_RS15420	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B6N31_RS15425	COG2501	S4 domain
B6N31_RS15430	COG0215	cysteine-tRNA ligase activity
B6N31_RS15440	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B6N31_RS15445	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B6N31_RS15450	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B6N31_RS15455	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B6N31_RS15460	COG0814	amino acid
B6N31_RS15465	COG1760	l-serine dehydratase
B6N31_RS15485	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B6N31_RS15490	COG0581	inorganic phosphate transmembrane transporter activity
B6N31_RS15500	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
B6N31_RS15515	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B6N31_RS15520	COG0589	response to stress
B6N31_RS15540	COG0670	Belongs to the BI1 family
B6N31_RS15545	COG2920	part of a sulfur-relay system
B6N31_RS15550	COG1254	Belongs to the acylphosphatase family
B6N31_RS15555	COG3785	DNA binding
B6N31_RS15560	COG1832	CoA-binding protein
B6N31_RS15570	COG1803	Methylglyoxal synthase
B6N31_RS15575	COG0210	DNA helicase
B6N31_RS15580	COG3304	Inner membrane component domain
B6N31_RS15585	COG1289	transmembrane transporter activity
B6N31_RS15590	COG3070	regulator of competence-specific genes
B6N31_RS15595	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
B6N31_RS15600	COG2885	chlorophyll binding
B6N31_RS15600	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
B6N31_RS15630	COG0667	Aldo Keto reductase
B6N31_RS15635	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B6N31_RS15640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B6N31_RS15645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B6N31_RS15650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B6N31_RS15655	COG0477	Major facilitator Superfamily
B6N31_RS15660	COG2205	protein histidine kinase activity
B6N31_RS15665	COG0745	RESPONSE REGULATOR receiver
B6N31_RS15670	COG0435	Glutathione S-transferase
B6N31_RS15675	COG0826	peptidase U32
B6N31_RS15680	COG3223	Belongs to the PsiE family
B6N31_RS15685	COG3622	Belongs to the hyi family
B6N31_RS15690	COG2211	Major facilitator Superfamily
B6N31_RS15700	COG0673	inositol 2-dehydrogenase activity
B6N31_RS15715	COG0351	phosphomethylpyrimidine kinase
B6N31_RS15720	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
B6N31_RS15725	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B6N31_RS15730	COG2814	Major facilitator Superfamily
B6N31_RS15740	COG2192	nodulation
B6N31_RS15755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B6N31_RS15760	COG0765	amino acid transport
B6N31_RS15770	COG0765	amino acid transport
B6N31_RS15775	COG0477	Major facilitator Superfamily
B6N31_RS15810	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B6N31_RS15825	COG2207	Transcriptional regulator
B6N31_RS15840	COG2814	Major facilitator Superfamily
B6N31_RS15845	COG0583	DNA-binding transcription factor activity
B6N31_RS15855	COG0604	alcohol dehydrogenase
B6N31_RS15865	COG1733	regulation of RNA biosynthetic process
B6N31_RS15870	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B6N31_RS15870	COG0519	Catalyzes the synthesis of GMP from XMP
B6N31_RS15875	COG0517	IMP dehydrogenase activity
B6N31_RS15875	COG0516	GMP reductase activity
B6N31_RS15880	COG1570	exodeoxyribonuclease VII activity
B6N31_RS15900	COG1160	GTP binding
B6N31_RS15905	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B6N31_RS15910	COG2976	Protein conserved in bacteria
B6N31_RS15915	COG0124	histidyl-tRNA synthetase
B6N31_RS15920	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B6N31_RS15925	COG1426	Protein conserved in bacteria
B6N31_RS15935	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B6N31_RS15940	COG0105	UTP biosynthetic process
B6N31_RS15945	COG2897	thiosulfate sulfurtransferase activity
B6N31_RS15960	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B6N31_RS15965	COG2975	iron-sulfur cluster assembly
B6N31_RS15970	COG0633	Ferredoxin
B6N31_RS15975	COG0443	Heat shock 70 kDa protein
B6N31_RS15980	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
B6N31_RS15985	COG0316	Belongs to the HesB IscA family
B6N31_RS15990	COG0822	iron-sulfur transferase activity
B6N31_RS16000	COG1959	2 iron, 2 sulfur cluster binding
B6N31_RS16005	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
B6N31_RS16010	COG0483	inositol monophosphate 1-phosphatase activity
B6N31_RS16020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B6N31_RS16025	COG1120	ATPase activity
B6N31_RS16035	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
B6N31_RS16040	COG3683	transport system, periplasmic component
B6N31_RS16045	COG2814	Major facilitator Superfamily
B6N31_RS16050	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B6N31_RS16055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B6N31_RS16055	COG1017	nitric oxide dioxygenase activity
B6N31_RS16060	COG3866	Pectate lyase
B6N31_RS16080	COG4677	pectinesterase activity
B6N31_RS16085	COG0347	Belongs to the P(II) protein family
B6N31_RS16090	COG2204	response regulator
B6N31_RS16095	COG3170	Tfp pilus assembly protein FimV
B6N31_RS16100	COG2205	protein histidine kinase activity
B6N31_RS16105	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B6N31_RS16105	COG0047	phosphoribosylformylglycinamidine synthase activity
B6N31_RS16110	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
B6N31_RS16120	COG0560	Phosphoserine phosphatase
B6N31_RS16125	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
B6N31_RS16150	COG2200	EAL domain
B6N31_RS16155	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B6N31_RS16160	COG0736	holo-[acyl-carrier-protein] synthase activity
B6N31_RS16165	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
B6N31_RS16170	COG1381	Involved in DNA repair and RecF pathway recombination
B6N31_RS16175	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B6N31_RS16180	COG0571	ribonuclease III activity
B6N31_RS16190	COG0481	GTPase activity
B6N31_RS16195	COG3086	response to oxidative stress
B6N31_RS16200	COG3026	antisigma factor binding
B6N31_RS16215	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
B6N31_RS16220	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
B6N31_RS16225	COG0513	Belongs to the DEAD box helicase family
B6N31_RS16230	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
B6N31_RS16235	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B6N31_RS16250	COG2873	o-acetylhomoserine
B6N31_RS16255	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B6N31_RS16285	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
B6N31_RS16290	COG4208	sulfate ABC transporter
B6N31_RS16295	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
B6N31_RS16300	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
B6N31_RS16305	COG3835	regulator
B6N31_RS16315	COG0232	Belongs to the dGTPase family. Type 2 subfamily
B6N31_RS16320	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B6N31_RS16325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B6N31_RS16345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B6N31_RS16350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B6N31_RS16355	COG1120	ATPase activity
B6N31_RS16360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B6N31_RS16365	COG1643	Atp-dependent helicase
B6N31_RS16370	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
B6N31_RS16375	COG1489	DNA binding
B6N31_RS16380	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B6N31_RS16385	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B6N31_RS16390	COG0617	tRNA 3'-terminal CCA addition
B6N31_RS16395	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B6N31_RS16400	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B6N31_RS16405	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B6N31_RS16410	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
B6N31_RS16415	COG0842	Transport permease protein
B6N31_RS16420	COG1131	(ABC) transporter
B6N31_RS16425	COG0288	reversible hydration of carbon dioxide
B6N31_RS16430	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
B6N31_RS16445	COG3842	ATPase activity
B6N31_RS16460	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
B6N31_RS16465	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
B6N31_RS16475	COG1780	Probably involved in ribonucleotide reductase function
B6N31_RS16480	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B6N31_RS16485	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B6N31_RS16495	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B6N31_RS16500	COG0328	RNA-DNA hybrid ribonuclease activity
B6N31_RS16505	COG2226	methyltransferase
B6N31_RS16510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B6N31_RS16515	COG1388	LysM domain
B6N31_RS16515	COG0741	lytic transglycosylase activity
B6N31_RS16520	COG3021	interspecies interaction between organisms
B6N31_RS16550	COG0542	response to heat
B6N31_RS16555	COG1496	oxidoreductase activity
B6N31_RS16560	COG0564	pseudouridine synthase activity
B6N31_RS16565	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B6N31_RS16570	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B6N31_RS16575	COG1605	Chorismate mutase
B6N31_RS16575	COG0077	Prephenate dehydratase
B6N31_RS16580	COG0287	Prephenate dehydrogenase
B6N31_RS16580	COG1605	Chorismate mutase
B6N31_RS16585	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B6N31_RS16600	COG0335	large ribosomal subunit rRNA binding
B6N31_RS16605	COG0336	Belongs to the RNA methyltransferase TrmD family
B6N31_RS16610	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B6N31_RS16615	COG0228	four-way junction DNA binding
B6N31_RS16620	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B6N31_RS16625	COG4137	Cytochrome C assembly protein
B6N31_RS16630	COG1854	S-ribosylhomocysteine lyase activity
B6N31_RS16635	COG2918	glutathione biosynthetic process
B6N31_RS16640	COG1238	metal cluster binding
B6N31_RS16645	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B6N31_RS16670	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
B6N31_RS16675	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B6N31_RS16680	COG2137	regulation of response to DNA damage stimulus
B6N31_RS16685	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B6N31_RS16700	COG3038	cytochrome b561
B6N31_RS16745	COG1879	ABC-type sugar transport system periplasmic component
B6N31_RS16750	COG1129	ABC transporter
B6N31_RS16755	COG1172	Belongs to the binding-protein-dependent transport system permease family
B6N31_RS16760	COG1172	Belongs to the binding-protein-dependent transport system permease family
B6N31_RS16765	COG0688	phosphatidylethanolamine metabolic process
B6N31_RS16775	COG2207	Transcriptional regulator
B6N31_RS16785	COG0523	cobalamin synthesis protein
B6N31_RS16790	COG2879	small protein
B6N31_RS16795	COG1966	Carbon starvation protein
B6N31_RS16805	COG3275	phosphorelay sensor kinase activity
B6N31_RS16815	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B6N31_RS16835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B6N31_RS16840	COG1696	Membrane protein involved in D-alanine export
B6N31_RS16860	COG2161	toxin-antitoxin pair type II binding
B6N31_RS16895	COG1196	nuclear chromosome segregation
B6N31_RS16910	COG3423	Transcriptional regulator
B6N31_RS16930	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B6N31_RS16935	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B6N31_RS16945	COG2199	diguanylate cyclase activity
B6N31_RS16955	COG1073	alpha beta
B6N31_RS16960	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
B6N31_RS16970	COG2195	Cleaves the N-terminal amino acid of tripeptides
B6N31_RS16975	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B6N31_RS16980	COG3034	peptidoglycan biosynthetic process
B6N31_RS16985	COG0121	glutamine amidotransferase
B6N31_RS16990	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
B6N31_RS16995	COG1960	acyl-CoA dehydrogenase activity
B6N31_RS17000	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
B6N31_RS17005	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
B6N31_RS17010	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
B6N31_RS17015	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
B6N31_RS17020	COG0235	Class ii aldolase
B6N31_RS17025	COG0436	Aminotransferase
B6N31_RS17040	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B6N31_RS17050	COG0765	amino acid transport
B6N31_RS17055	COG0765	amino acid transport
B6N31_RS17105	COG1953	Uracil, thiamine, allantoin
B6N31_RS17120	COG4175	Glycine betaine
B6N31_RS17125	COG4176	ABC-type proline glycine betaine transport system permease component
B6N31_RS17130	COG2113	Glycine betaine
B6N31_RS17135	COG2814	Major facilitator Superfamily
B6N31_RS17140	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
B6N31_RS17150	COG1846	Transcriptional regulator
B6N31_RS17155	COG1566	PFAM secretion protein HlyD family protein
B6N31_RS17160	COG2814	Major facilitator Superfamily
B6N31_RS17165	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B6N31_RS17170	COG3118	belongs to the thioredoxin family
B6N31_RS17175	COG3148	PFAM DTW domain containing protein
B6N31_RS17180	COG0045	succinate-CoA ligase (ADP-forming) activity
B6N31_RS17180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B6N31_RS17180	COG1042	CoA-binding domain protein
B6N31_RS17185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B6N31_RS17190	COG5544	Lipoprotein
B6N31_RS17195	COG0477	Major facilitator Superfamily
B6N31_RS17240	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
B6N31_RS17250	COG2011	ABC-type metal ion transport system permease component
B6N31_RS17255	COG1464	Belongs to the NlpA lipoprotein family
B6N31_RS17265	COG1720	tRNA m6t6A37 methyltransferase activity
B6N31_RS17270	COG0442	prolyl-tRNA aminoacylation
B6N31_RS17280	COG1388	LysM domain
B6N31_RS17280	COG4942	peptidase
B6N31_RS17285	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B6N31_RS17290	COG0585	pseudouridine synthase activity
B6N31_RS17295	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
B6N31_RS17300	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B6N31_RS17305	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
B6N31_RS17315	COG0529	Catalyzes the synthesis of activated sulfate
B6N31_RS17320	COG2895	sulfate adenylyltransferase (ATP) activity
B6N31_RS17330	COG1648	precorrin-2 dehydrogenase activity
B6N31_RS17330	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B6N31_RS17335	COG0175	sulfate reduction
B6N31_RS17340	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B6N31_RS17345	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B6N31_RS17365	COG0720	synthase
B6N31_RS17370	COG0602	queuosine metabolic process
B6N31_RS17380	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
B6N31_RS17395	COG0504	CTP synthase activity
B6N31_RS17400	COG3956	TIGRFAM MazG family protein
B6N31_RS17405	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B6N31_RS17410	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B6N31_RS17420	COG1929	Belongs to the glycerate kinase type-1 family
B6N31_RS17425	COG2084	Dehydrogenase
B6N31_RS17435	COG4948	Mandelate Racemase Muconate Lactonizing
B6N31_RS17440	COG4948	Mandelate Racemase Muconate Lactonizing
B6N31_RS17445	COG2271	Major facilitator Superfamily
B6N31_RS17450	COG2721	sulfolactate sulfo-lyase activity
B6N31_RS17455	COG0840	transmembrane signaling receptor activity
B6N31_RS17475	COG3530	Putative quorum-sensing-regulated virulence factor
B6N31_RS17480	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B6N31_RS17485	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
B6N31_RS17485	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
B6N31_RS17490	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
B6N31_RS17495	COG3025	triphosphatase activity
B6N31_RS17500	COG4991	sh3 domain protein
B6N31_RS17505	COG0617	tRNA 3'-terminal CCA addition
B6N31_RS17510	COG1968	undecaprenyl-diphosphatase activity
B6N31_RS17515	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B6N31_RS17520	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
B6N31_RS17530	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
B6N31_RS17535	COG2105	PFAM AIG2 family protein
B6N31_RS17545	COG0729	surface antigen
B6N31_RS17550	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B6N31_RS17555	COG1253	flavin adenine dinucleotide binding
B6N31_RS17565	COG1218	3'(2'),5'-bisphosphate nucleotidase
B6N31_RS17570	COG0737	Belongs to the 5'-nucleotidase family
B6N31_RS17575	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
B6N31_RS17585	COG0545	Peptidyl-prolyl cis-trans isomerase
B6N31_RS17590	COG3061	Opacity-associated protein A
B6N31_RS17600	COG0359	binds to the 23S rRNA
B6N31_RS17605	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B6N31_RS17610	COG2965	DNA replication, synthesis of RNA primer
B6N31_RS17620	COG1073	alpha beta
B6N31_RS17625	COG0840	transmembrane signaling receptor activity
B6N31_RS17640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B6N31_RS17645	COG0557	exoribonuclease II activity
B6N31_RS17650	COG1959	2 iron, 2 sulfur cluster binding
B6N31_RS17665	COG0402	S-adenosylhomocysteine deaminase activity
B6N31_RS17680	COG2805	Type II/IV secretion system protein
B6N31_RS17685	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B6N31_RS17690	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B6N31_RS17695	COG0762	integral membrane protein
B6N31_RS17700	COG1872	DUF167
B6N31_RS17705	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
B6N31_RS17710	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B6N31_RS17720	COG2153	protein acetylation
B6N31_RS17725	COG0477	Major facilitator Superfamily
B6N31_RS17730	COG0318	PFAM AMP-dependent synthetase and ligase
B6N31_RS17730	COG0204	Acyl-transferase
B6N31_RS17735	COG2723	6-phospho-beta-galactosidase activity
B6N31_RS17740	COG2723	6-phospho-beta-galactosidase activity
B6N31_RS17745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B6N31_RS17745	COG1263	PTS System
B6N31_RS17745	COG2190	(PTS) system
B6N31_RS17750	COG3711	transcriptional antiterminator
B6N31_RS17760	COG1609	Transcriptional regulator
B6N31_RS17770	COG2186	Transcriptional regulator
B6N31_RS17775	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B6N31_RS17780	COG2723	6-phospho-beta-galactosidase activity
B6N31_RS17785	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B6N31_RS17790	COG1447	Phosphotransferase system cellobiose-specific component IIA
B6N31_RS17795	COG1609	Transcriptional regulator
B6N31_RS17805	COG0583	DNA-binding transcription factor activity
B6N31_RS17810	COG3842	ATPase activity
B6N31_RS17820	COG4149	molybdate abc transporter
B6N31_RS17825	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
B6N31_RS17845	COG5642	Protein of unknown function (DUF2384)
B6N31_RS17850	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B6N31_RS17860	COG2124	cytochrome p450
B6N31_RS17875	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B6N31_RS17895	COG1522	sequence-specific DNA binding
B6N31_RS17905	COG1448	Aminotransferase
B6N31_RS17940	COG1203	CRISPR-associated helicase, Cas3
B6N31_RS17945	COG1518	maintenance of DNA repeat elements
B6N31_RS17950	COG0840	transmembrane signaling receptor activity
B6N31_RS17960	COG2199	diguanylate cyclase activity
B6N31_RS17960	COG2203	Gaf domain
B6N31_RS17965	COG0432	Pfam Uncharacterised protein family UPF0047
B6N31_RS17970	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B6N31_RS17990	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B6N31_RS18090	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B6N31_RS18095	COG1609	Transcriptional regulator
B6N31_RS18100	COG0395	ABC-type sugar transport system, permease component
B6N31_RS18105	COG1175	transmembrane transport
B6N31_RS18110	COG3842	ATPase activity
B6N31_RS18115	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
B6N31_RS18135	COG2971	BadF BadG BcrA BcrD
B6N31_RS18145	COG0725	ABC transporter, periplasmic molybdate-binding protein
B6N31_RS18150	COG1121	(ABC) transporter
B6N31_RS18155	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B6N31_RS18160	COG0803	Belongs to the bacterial solute-binding protein 9 family
B6N31_RS18165	COG2368	4-hydroxyphenylacetate
B6N31_RS18205	COG1349	DNA-binding transcription factor activity
B6N31_RS18210	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B6N31_RS18215	COG3395	kinase activity
B6N31_RS18220	COG1454	alcohol dehydrogenase
B6N31_RS18225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B6N31_RS18240	COG2731	YhcH YjgK YiaL family protein
B6N31_RS18250	COG0861	Integral membrane protein TerC family
B6N31_RS18255	COG3112	Uncharacterised protein family (UPF0231)
B6N31_RS18270	COG4771	TonB-dependent receptor
B6N31_RS18275	COG4977	sequence-specific DNA binding
B6N31_RS18280	COG2079	MmgE PrpD family protein
B6N31_RS18290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B6N31_RS18295	COG0508	dehydrogenase complex catalyzes the overall conversion of
B6N31_RS18300	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
B6N31_RS18310	COG1113	amino acid transport
B6N31_RS18315	COG3725	Membrane protein required for beta-lactamase induction
B6N31_RS18320	COG3023	N-Acetylmuramoyl-L-alanine amidase
B6N31_RS18325	COG3248	Nucleoside-binding outer membrane protein
B6N31_RS18335	COG4969	Belongs to the N-Me-Phe pilin family
B6N31_RS18340	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B6N31_RS18345	COG1459	type II secretion system
B6N31_RS18350	COG0516	GMP reductase activity
B6N31_RS18355	COG0237	dephospho-CoA kinase activity
B6N31_RS18360	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
B6N31_RS18365	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
B6N31_RS18370	COG0494	nUDIX hydrolase
B6N31_RS18375	COG0653	protein targeting
B6N31_RS18390	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
B6N31_RS18395	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B6N31_RS18400	COG0849	cell division
B6N31_RS18405	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B6N31_RS18410	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B6N31_RS18415	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B6N31_RS18420	COG0772	Belongs to the SEDS family
B6N31_RS18425	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B6N31_RS18430	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B6N31_RS18435	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B6N31_RS18440	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B6N31_RS18445	COG0768	penicillin binding
B6N31_RS18450	COG3116	cell division
B6N31_RS18455	COG0275	rRNA processing
B6N31_RS18460	COG2001	Belongs to the MraZ family
B6N31_RS18480	COG0028	Belongs to the TPP enzyme family
B6N31_RS18485	COG1022	Amp-dependent synthetase and ligase
B6N31_RS18495	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B6N31_RS18500	COG0473	3-isopropylmalate dehydrogenase activity
B6N31_RS18505	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B6N31_RS18510	COG0066	3-isopropylmalate dehydratase activity
B6N31_RS18530	COG3033	Beta-eliminating lyase
B6N31_RS18540	COG4533	DNA binding
B6N31_RS18550	COG1178	ABC-type Fe3 transport system permease component
B6N31_RS18555	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
B6N31_RS18565	COG0028	Belongs to the TPP enzyme family
B6N31_RS18570	COG0440	acetolactate synthase activity
B6N31_RS18575	COG0586	Pfam SNARE associated Golgi protein
B6N31_RS18600	COG3157	Type VI secretion system effector, Hcp
B6N31_RS18610	COG0411	ABC transporter
B6N31_RS18630	COG0417	DNA replication proofreading
B6N31_RS18635	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B6N31_RS18640	COG0564	pseudouridine synthase activity
B6N31_RS18645	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
B6N31_RS18650	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
B6N31_RS18655	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B6N31_RS18660	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B6N31_RS18665	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B6N31_RS18670	COG2967	ApaG domain
B6N31_RS18675	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B6N31_RS18685	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B6N31_RS18690	COG3610	response to peptide
B6N31_RS18695	COG2966	Psort location CytoplasmicMembrane, score
B6N31_RS18700	COG1280	lysine exporter protein (LysE YggA)
B6N31_RS18705	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B6N31_RS18710	COG0505	Belongs to the CarA family
B6N31_RS18725	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B6N31_RS18730	COG1047	Peptidyl-prolyl cis-trans
B6N31_RS18735	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B6N31_RS18740	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B6N31_RS18745	COG0196	riboflavin kinase activity
B6N31_RS18750	COG0268	Binds directly to 16S ribosomal RNA
B6N31_RS18755	COG0583	DNA-binding transcription factor activity
B6N31_RS18760	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
B6N31_RS18765	COG0484	heat shock protein binding
B6N31_RS18775	COG1584	GPR1 FUN34 yaaH family protein
B6N31_RS18785	COG0521	Mo-molybdopterin cofactor biosynthetic process
B6N31_RS18790	COG3706	GGDEF domain
B6N31_RS18795	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B6N31_RS18800	COG3022	response to hydroperoxide
B6N31_RS18810	COG0083	homoserine kinase activity
B6N31_RS18820	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
B6N31_RS18825	COG0745	RESPONSE REGULATOR receiver
B6N31_RS18830	COG3045	CreA protein
B6N31_RS18835	COG2207	Transcriptional regulator
B6N31_RS18835	COG3708	Transcriptional regulator
B6N31_RS18840	COG0406	alpha-ribazole phosphatase activity
B6N31_RS18845	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
B6N31_RS18850	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
B6N31_RS18860	COG0488	(ABC) transporter
B6N31_RS18865	COG0840	transmembrane signaling receptor activity
B6N31_RS18870	COG0583	DNA-binding transcription factor activity
B6N31_RS18875	COG0604	alcohol dehydrogenase
B6N31_RS18880	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B6N31_RS18885	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
B6N31_RS18890	COG0583	DNA-binding transcription factor activity
B6N31_RS18895	COG2968	Membrane
B6N31_RS18900	COG1414	Transcriptional regulator
B6N31_RS18905	COG0668	transmembrane transport
B6N31_RS18915	COG0126	phosphoglycerate kinase activity
B6N31_RS18920	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B6N31_RS18925	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B6N31_RS18930	COG0738	Major facilitator superfamily
B6N31_RS18935	COG1166	arginine decarboxylase activity
B6N31_RS18950	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B6N31_RS18955	COG3091	SprT-like family
B6N31_RS18960	COG2356	endonuclease I
B6N31_RS18965	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B6N31_RS18970	COG0189	ligase activity
B6N31_RS18975	COG1678	Uncharacterized ACR, COG1678
B6N31_RS18980	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B6N31_RS18985	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
B6N31_RS18990	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B6N31_RS18995	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B6N31_RS19000	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
B6N31_RS19005	COG0330	HflC and HflK could
B6N31_RS19010	COG0330	HflC and HflK could
B6N31_RS19015	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B6N31_RS19020	COG1923	regulation of RNA biosynthetic process
B6N31_RS19025	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B6N31_RS19030	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
B6N31_RS19040	COG0802	atpase or kinase
B6N31_RS19045	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
B6N31_RS19045	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B6N31_RS19055	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B6N31_RS19075	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
B6N31_RS19090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B6N31_RS19100	COG0438	transferase activity, transferring glycosyl groups
B6N31_RS19100	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B6N31_RS19125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B6N31_RS19130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B6N31_RS19150	COG0765	amino acid transport
B6N31_RS19155	COG1126	abc transporter atp-binding protein
B6N31_RS19165	COG1764	response to oxidative stress
B6N31_RS19170	COG1846	Transcriptional regulator
B6N31_RS19175	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
B6N31_RS19180	COG1473	amidohydrolase
B6N31_RS19190	COG0583	DNA-binding transcription factor activity
B6N31_RS19195	COG0840	transmembrane signaling receptor activity
B6N31_RS19210	COG3604	Transcriptional regulator
B6N31_RS19215	COG2205	protein histidine kinase activity
B6N31_RS19230	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B6N31_RS19295	COG0840	transmembrane signaling receptor activity
B6N31_RS19310	COG3550	peptidyl-serine autophosphorylation
B6N31_RS19375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B6N31_RS19425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B6N31_RS19425	COG3321	synthase
B6N31_RS19425	COG4221	oxidoreductase activity
B6N31_RS19425	COG1028	Short-chain dehydrogenase reductase Sdr
B6N31_RS19430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B6N31_RS19440	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
B6N31_RS19445	COG1162	GTPase activity
B6N31_RS19450	COG0688	phosphatidylethanolamine metabolic process
B6N31_RS19455	COG3264	Mechanosensitive ion channel
B6N31_RS19455	COG1511	domain protein
B6N31_RS19460	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
B6N31_RS19465	COG1053	succinate dehydrogenase
B6N31_RS19470	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B6N31_RS19475	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
B6N31_RS19480	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
B6N31_RS19485	COG3040	lipid binding
B6N31_RS19495	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B6N31_RS19500	COG1509	lysine 2,3-aminomutase activity
B6N31_RS19510	COG4124	Belongs to the glycosyl hydrolase 26 family
B6N31_RS19515	COG0166	Belongs to the GPI family
B6N31_RS19520	COG0527	aspartate kinase activity
B6N31_RS19530	COG1283	sodium-dependent phosphate transmembrane transporter activity
B6N31_RS19535	COG0471	metal ion transport
B6N31_RS19550	COG0646	methionine synthase
B6N31_RS19550	COG1410	methionine synthase
B6N31_RS19560	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
B6N31_RS19570	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B6N31_RS19575	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
B6N31_RS19605	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B6N31_RS19615	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B6N31_RS19620	COG0009	L-threonylcarbamoyladenylate synthase
B6N31_RS19625	COG0551	DNA topoisomerase type I activity
B6N31_RS19630	COG2922	Belongs to the Smg family
B6N31_RS19635	COG0758	DNA mediated transformation
B6N31_RS19640	COG0242	peptide deformylase activity
B6N31_RS19645	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B6N31_RS19650	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B6N31_RS19650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B6N31_RS19660	COG1970	mechanosensitive ion channel activity
B6N31_RS19665	COG3036	rescue of stalled ribosome
B6N31_RS19675	COG0203	ribosomal protein L17
B6N31_RS19685	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B6N31_RS19695	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B6N31_RS19700	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B6N31_RS19705	COG0201	protein transport
B6N31_RS19710	COG0200	Binds to the 23S rRNA
B6N31_RS19715	COG1841	ribosomal large subunit assembly
B6N31_RS19720	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B6N31_RS19730	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B6N31_RS19740	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B6N31_RS19745	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B6N31_RS19770	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B6N31_RS19780	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B6N31_RS19785	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
B6N31_RS19790	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B6N31_RS19795	COG0089	rRNA binding
B6N31_RS19800	COG0088	Forms part of the polypeptide exit tunnel
B6N31_RS19805	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B6N31_RS19810	COG0051	transcription antitermination factor activity, RNA binding
B6N31_RS19825	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B6N31_RS19830	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B6N31_RS19835	COG0049	tRNA binding
B6N31_RS19840	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B6N31_RS19845	COG2168	tRNA wobble position uridine thiolation
B6N31_RS19850	COG2923	Belongs to the DsrF TusC family
B6N31_RS19855	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
B6N31_RS19860	COG2964	Protein conserved in bacteria
B6N31_RS19865	COG2194	sulfuric ester hydrolase activity
B6N31_RS19870	COG0745	RESPONSE REGULATOR receiver
B6N31_RS19875	COG0642	Histidine kinase
B6N31_RS19880	COG0545	Peptidyl-prolyl cis-trans isomerase
B6N31_RS19885	COG2900	Belongs to the SlyX family
B6N31_RS19895	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B6N31_RS19905	COG2140	Oxalate decarboxylase
B6N31_RS19910	COG1047	Peptidyl-prolyl cis-trans
B6N31_RS19915	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
B6N31_RS19920	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B6N31_RS19920	COG0475	glutathione-regulated potassium exporter activity
B6N31_RS19925	COG2249	NAD(P)H dehydrogenase (quinone) activity
B6N31_RS19930	COG0488	(ABC) transporter
B6N31_RS19940	COG0429	hydrolase of the alpha beta-hydrolase fold
B6N31_RS19950	COG3954	Phosphoribulokinase
B6N31_RS19955	COG1765	OsmC-like protein
B6N31_RS19975	COG2207	Transcriptional regulator
B6N31_RS19975	COG4753	response regulator
B6N31_RS19985	COG1404	Belongs to the peptidase S8 family
B6N31_RS19990	COG3179	chitinase
B6N31_RS20010	COG0076	glutamate decarboxylase activity
B6N31_RS20030	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B6N31_RS20035	COG4948	Mandelate Racemase Muconate Lactonizing
B6N31_RS20045	COG0546	phosphoglycolate phosphatase activity
B6N31_RS20050	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B6N31_RS20065	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B6N31_RS20070	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B6N31_RS20075	COG4796	Type ii and iii secretion system protein
B6N31_RS20100	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
B6N31_RS20105	COG0494	nUDIX hydrolase
B6N31_RS20115	COG1011	Hydrolase
B6N31_RS20120	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
B6N31_RS20125	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
B6N31_RS20130	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
B6N31_RS20145	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B6N31_RS20155	COG2183	response to ionizing radiation
B6N31_RS20170	COG3157	Type VI secretion system effector, Hcp
B6N31_RS20175	COG2267	carboxylic ester hydrolase activity
B6N31_RS20185	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
B6N31_RS20185	COG0316	Belongs to the HesB IscA family
B6N31_RS20190	COG1640	4-alpha-glucanotransferase
B6N31_RS20195	COG0058	SHG alpha-glucan phosphorylase activity
B6N31_RS20200	COG1349	DNA-binding transcription factor activity
B6N31_RS20205	COG0705	Rhomboid family
B6N31_RS20210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B6N31_RS20220	COG2731	YhcH YjgK YiaL family protein
B6N31_RS20225	COG2271	Major facilitator Superfamily
B6N31_RS20230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B6N31_RS20235	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B6N31_RS20245	COG0058	SHG alpha-glucan phosphorylase activity
B6N31_RS20250	COG0297	glycogen (starch) synthase activity
B6N31_RS20255	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B6N31_RS20270	COG3275	phosphorelay sensor kinase activity
B6N31_RS20275	COG1278	Cold shock
B6N31_RS20285	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B6N31_RS20290	COG2095	MarC family integral membrane protein
B6N31_RS20295	COG2610	gluconate transmembrane transporter activity
B6N31_RS20300	COG3265	gluconokinase activity
B6N31_RS20305	COG1609	Transcriptional regulator
B6N31_RS20315	COG1741	Belongs to the pirin family
B6N31_RS20325	COG0247	lactate metabolic process
B6N31_RS20330	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
B6N31_RS20335	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B6N31_RS20340	COG2271	Major facilitator Superfamily
B6N31_RS20345	COG0584	glycerophosphoryl diester phosphodiesterase
B6N31_RS20350	COG0561	phosphatase activity
B6N31_RS20355	COG2267	carboxylic ester hydrolase activity
B6N31_RS20360	COG1280	lysine exporter protein (LysE YggA)
B6N31_RS20375	COG1280	lysine exporter protein (LysE YggA)
B6N31_RS20380	COG0514	ATP-dependent DNA helicase (RecQ)
B6N31_RS20385	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
B6N31_RS20390	COG2050	protein possibly involved in aromatic compounds catabolism
B6N31_RS20400	COG3180	Ammonia monooxygenase
B6N31_RS20405	COG0598	Magnesium transport protein CorA
B6N31_RS20410	COG0210	DNA helicase
B6N31_RS20415	COG1011	Hydrolase
B6N31_RS20430	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B6N31_RS20450	COG0181	hydroxymethylbilane synthase activity
B6N31_RS20455	COG1587	Uroporphyrinogen-III synthase
B6N31_RS20460	COG2959	enzyme of heme biosynthesis
B6N31_RS20465	COG3071	HemY protein
B6N31_RS20470	COG1473	amidohydrolase
B6N31_RS20475	COG1126	abc transporter atp-binding protein
B6N31_RS20480	COG0765	amino acid transport
B6N31_RS20485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B6N31_RS20490	COG0456	acetyltransferase
B6N31_RS20495	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B6N31_RS20530	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
B6N31_RS20540	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B6N31_RS20545	COG2244	polysaccharide biosynthetic process
B6N31_RS20550	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B6N31_RS20560	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
B6N31_RS20565	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
B6N31_RS20570	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
B6N31_RS20575	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B6N31_RS20580	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B6N31_RS20585	COG3118	belongs to the thioredoxin family
B6N31_RS20590	COG0513	Belongs to the DEAD box helicase family
B6N31_RS20595	COG0248	Ppx GppA phosphatase
B6N31_RS20610	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B6N31_RS20620	COG0506	proline dehydrogenase activity
B6N31_RS20620	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
B6N31_RS20620	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
B6N31_RS20625	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B6N31_RS20635	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B6N31_RS20655	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B6N31_RS20665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B6N31_RS20670	COG3978	acetolactate synthase activity
B6N31_RS20685	COG2814	Major facilitator Superfamily
B6N31_RS20695	COG3085	chromosome segregation
B6N31_RS20700	COG0583	DNA-binding transcription factor activity
B6N31_RS20740	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B6N31_RS20750	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B6N31_RS20765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B6N31_RS20775	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B6N31_RS20775	COG0678	peroxiredoxin activity
B6N31_RS20785	COG0527	aspartate kinase activity
B6N31_RS20785	COG0460	homoserine dehydrogenase
B6N31_RS20790	COG0626	cystathionine gamma-synthase activity
B6N31_RS20795	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
B6N31_RS20805	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B6N31_RS20810	COG1609	Transcriptional regulator
B6N31_RS20815	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B6N31_RS20820	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
B6N31_RS20825	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
B6N31_RS20830	COG1575	Belongs to the MenA family. Type 1 subfamily
B6N31_RS20835	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B6N31_RS20840	COG3074	FtsZ-dependent cytokinesis
B6N31_RS20845	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B6N31_RS20855	COG1494	fructose-1,6-bisphosphatase
B6N31_RS20865	COG3152	Membrane
B6N31_RS20875	COG0149	triose-phosphate isomerase activity
B6N31_RS20885	COG2957	Belongs to the agmatine deiminase family
B6N31_RS20890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B6N31_RS20900	COG0205	6-phosphofructokinase activity
B6N31_RS20905	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
B6N31_RS20950	COG3678	ATP-independent chaperone mediated protein folding
B6N31_RS20955	COG0745	RESPONSE REGULATOR receiver
B6N31_RS20960	COG2205	protein histidine kinase activity
B6N31_RS20980	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B6N31_RS20990	COG0679	Auxin Efflux Carrier
B6N31_RS20995	COG0584	glycerophosphoryl diester phosphodiesterase
B6N31_RS21000	COG3842	ATPase activity
B6N31_RS21005	COG0395	ABC-type sugar transport system, permease component
B6N31_RS21010	COG1175	transmembrane transport
B6N31_RS21015	COG1653	transport
B6N31_RS21025	COG0840	transmembrane signaling receptor activity
B6N31_RS21030	COG0840	transmembrane signaling receptor activity
B6N31_RS21035	COG0840	transmembrane signaling receptor activity
B6N31_RS21040	COG0840	transmembrane signaling receptor activity
B6N31_RS21050	COG0840	transmembrane signaling receptor activity
B6N31_RS21070	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B6N31_RS21075	COG0179	Fumarylacetoacetate (FAA) hydrolase
B6N31_RS21080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B6N31_RS21090	COG0411	ABC transporter
B6N31_RS21095	COG4177	L-phenylalanine transmembrane transporter activity
B6N31_RS21100	COG0559	Belongs to the binding-protein-dependent transport system permease family
B6N31_RS21105	COG0683	leucine binding
B6N31_RS21120	COG2177	Part of the ABC transporter FtsEX involved in
B6N31_RS21125	COG2884	Cell division ATP-binding protein ftsE
B6N31_RS21130	COG0552	protein localization to endoplasmic reticulum
B6N31_RS21130	COG0552	protein localization to endoplasmic reticulum
B6N31_RS21135	COG0742	ribosomal rna small subunit methyltransferase
B6N31_RS21140	COG3776	membrane
B6N31_RS21160	COG0425	Belongs to the sulfur carrier protein TusA family
B6N31_RS21165	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
B6N31_RS21175	COG0477	Major facilitator Superfamily
B6N31_RS21180	COG1295	ribonuclease BN
B6N31_RS21185	COG1942	4-Oxalocrotonate Tautomerase
B6N31_RS21190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B6N31_RS21200	COG1301	dicarboxylic acid transport
B6N31_RS21205	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
B6N31_RS21215	COG0457	Tetratricopeptide repeat
B6N31_RS21225	COG1215	transferase activity, transferring glycosyl groups
B6N31_RS21230	COG0489	protein tyrosine kinase activity
B6N31_RS21245	COG2378	regulation of single-species biofilm formation
B6N31_RS21255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B6N31_RS21275	COG4608	Belongs to the ABC transporter superfamily
B6N31_RS21280	COG0444	Belongs to the ABC transporter superfamily
B6N31_RS21285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B6N31_RS21290	COG0601	transmembrane transport
B6N31_RS21295	COG0747	negative chemotaxis
B6N31_RS21300	COG3493	citrate carrier protein
B6N31_RS21305	COG4565	transcriptional regulatory protein
B6N31_RS21310	COG3290	protein histidine kinase activity
B6N31_RS21315	COG0471	metal ion transport
B6N31_RS21320	COG0071	Belongs to the small heat shock protein (HSP20) family
B6N31_RS21325	COG0071	Belongs to the small heat shock protein (HSP20) family
B6N31_RS21330	COG5645	(Lipo)protein
B6N31_RS21340	COG0477	Major facilitator Superfamily
B6N31_RS21350	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B6N31_RS21360	COG1069	ribulokinase activity
B6N31_RS21365	COG0823	Involved in the tonB-independent uptake of proteins
B6N31_RS21385	COG0561	phosphatase activity
B6N31_RS21395	COG0589	response to stress
B6N31_RS21405	COG0306	phosphate transporter
B6N31_RS21410	COG2081	HI0933 family
B6N31_RS21425	COG3842	ATPase activity
B6N31_RS21430	COG0395	ABC-type sugar transport system, permease component
B6N31_RS21470	COG0697	spore germination
B6N31_RS21490	COG3048	D-serine ammonia-lyase activity
B6N31_RS21515	COG1653	transport
B6N31_RS21525	COG1175	transmembrane transport
B6N31_RS21535	COG2814	Major facilitator Superfamily
B6N31_RS21540	COG0583	DNA-binding transcription factor activity
B6N31_RS21555	COG4221	oxidoreductase activity
B6N31_RS21570	COG2194	sulfuric ester hydrolase activity
B6N31_RS21575	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B6N31_RS21580	COG0194	GDP metabolic process
B6N31_RS21590	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B6N31_RS21595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B6N31_RS21600	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B6N31_RS21605	COG2233	PERMEase
B6N31_RS21610	COG2982	Protein involved in outer membrane biogenesis
B6N31_RS21615	COG0456	acetyltransferase
B6N31_RS21620	COG1490	D-aminoacyl-tRNA deacylase activity
B6N31_RS21625	COG1011	Hydrolase
B6N31_RS21630	COG1217	gtp-binding protein TYPA
B6N31_RS21640	COG3852	Histidine kinase
B6N31_RS21655	COG3078	GTPase activator activity
B6N31_RS21660	COG0218	Necessary for normal cell division and for the maintenance of normal septation
B6N31_RS21665	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B6N31_RS21665	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B6N31_RS21670	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B6N31_RS21675	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B6N31_RS21680	COG3084	Protein conserved in bacteria
B6N31_RS21690	COG1763	Mo-molybdopterin cofactor biosynthetic process
B6N31_RS21715	COG1609	Transcriptional regulator
B6N31_RS21720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B6N31_RS21725	COG1879	ABC-type sugar transport system periplasmic component
B6N31_RS21730	COG1172	Belongs to the binding-protein-dependent transport system permease family
B6N31_RS21735	COG1129	ABC transporter
B6N31_RS21740	COG1869	D-ribose catabolic process
B6N31_RS21745	COG3111	PFAM Bacterial OB fold (BOF) protein
B6N31_RS21750	COG0745	RESPONSE REGULATOR receiver
B6N31_RS21760	COG3158	transport of potassium into the cell
B6N31_RS21765	COG0714	Associated with various cellular activities
B6N31_RS21770	COG2425	protein containing a von Willebrand factor type A (vWA) domain
B6N31_RS21775	COG1522	sequence-specific DNA binding
B6N31_RS21780	COG0716	FMN binding
B6N31_RS21785	COG0445	tRNA wobble uridine modification
B6N31_RS21790	COG0357	Ribosomal RNA small subunit methyltransferase G
B6N31_RS21795	COG3312	ion transport
B6N31_RS21800	COG0356	it plays a direct role in the translocation of protons across the membrane
B6N31_RS21810	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B6N31_RS21815	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B6N31_RS21820	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B6N31_RS21825	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B6N31_RS21830	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B6N31_RS21835	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B6N31_RS21845	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B6N31_RS21850	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B6N31_RS21855	COG3706	GGDEF domain
B6N31_RS21860	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B6N31_RS21865	COG0573	inorganic phosphate transmembrane transporter activity
B6N31_RS21870	COG0581	inorganic phosphate transmembrane transporter activity
B6N31_RS21875	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B6N31_RS21885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B6N31_RS21890	COG0765	amino acid transport
B6N31_RS21895	COG0765	amino acid transport
B6N31_RS21900	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B6N31_RS21905	COG2252	PERMEase
B6N31_RS21910	COG2091	lysine biosynthetic process via aminoadipic acid
B6N31_RS21915	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B6N31_RS21920	COG0493	'glutamate synthase
B6N31_RS21920	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B6N31_RS21945	COG0463	Glycosyl transferase, family 2
B6N31_RS21955	COG0726	polysaccharide deacetylase
B6N31_RS21960	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B6N31_RS21965	COG2076	Multidrug Resistance protein
B6N31_RS21970	COG2076	Multidrug Resistance protein
B6N31_RS21985	COG2910	NAD(P)H-binding
B6N31_RS21990	COG1733	regulation of RNA biosynthetic process
B6N31_RS22000	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B6N31_RS22015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B6N31_RS22030	COG3645	SOS response
B6N31_RS22035	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
B6N31_RS22040	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B6N31_RS22045	COG0706	membrane insertase activity
B6N31_RS22050	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B6N31_RS22055	COG0594	ribonuclease P activity
B6N31_RS22060	COG0230	Belongs to the bacterial ribosomal protein bL34 family