locus-tag	class	description
DYD83_RS00045	COG0592	DNA-directed DNA polymerase activity
DYD83_RS00050	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DYD83_RS00085	COG0742	ribosomal rna small subunit methyltransferase
DYD83_RS00090	COG0339	signal peptide processing
DYD83_RS00100	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DYD83_RS00105	COG1234	tRNA 3'-trailer cleavage
DYD83_RS00110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DYD83_RS00115	COG0471	metal ion transport
DYD83_RS00120	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DYD83_RS00125	COG2188	Transcriptional regulator
DYD83_RS00135	COG1522	sequence-specific DNA binding
DYD83_RS00140	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DYD83_RS00145	COG1509	lysine 2,3-aminomutase activity
DYD83_RS00165	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DYD83_RS00170	COG4191	Histidine kinase
DYD83_RS00190	COG0583	DNA-binding transcription factor activity
DYD83_RS00210	COG0837	glucose binding
DYD83_RS00225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DYD83_RS00230	COG4172	Belongs to the ABC transporter superfamily
DYD83_RS00245	COG0747	negative chemotaxis
DYD83_RS00255	COG3977	Valine--pyruvate aminotransferase
DYD83_RS00265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DYD83_RS00270	COG0456	acetyltransferase
DYD83_RS00275	COG2818	Glycosylase
DYD83_RS00280	COG0730	response to heat
DYD83_RS00285	COG0752	glycyl-tRNA synthetase alpha subunit
DYD83_RS00290	COG0751	glycine-tRNA ligase activity
DYD83_RS00305	COG3501	Rhs element vgr protein
DYD83_RS00325	COG3209	COG3209 Rhs family protein
DYD83_RS00325	COG4104	PAAR repeat-containing protein
DYD83_RS00350	COG3842	ATPase activity
DYD83_RS00370	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DYD83_RS00370	COG2213	PTS system mannitol-specific
DYD83_RS00375	COG0246	Mannitol dehydrogenase
DYD83_RS00380	COG3722	fumarate hydratase activity
DYD83_RS00390	COG0840	transmembrane signaling receptor activity
DYD83_RS00395	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DYD83_RS00400	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DYD83_RS00405	COG1012	belongs to the aldehyde dehydrogenase family
DYD83_RS00410	COG1070	Carbohydrate kinase
DYD83_RS00415	COG2115	Belongs to the xylose isomerase family
DYD83_RS00420	COG4213	ABC transporter substrate-binding protein
DYD83_RS00425	COG1129	ABC transporter
DYD83_RS00430	COG4214	carbohydrate transport
DYD83_RS00435	COG1609	Transcriptional regulator
DYD83_RS00435	COG2207	Transcriptional regulator
DYD83_RS00460	COG0137	argininosuccinate synthase activity
DYD83_RS00465	COG1846	Transcriptional regulator
DYD83_RS00470	COG0697	spore germination
DYD83_RS00475	COG2313	pseudouridylate synthase activity
DYD83_RS00480	COG0546	phosphoglycolate phosphatase activity
DYD83_RS00485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DYD83_RS00515	COG2207	Transcriptional regulator
DYD83_RS00515	COG1917	Cupin 2, conserved barrel domain protein
DYD83_RS00520	COG0577	efflux transmembrane transporter activity
DYD83_RS00520	COG1136	(ABC) transporter
DYD83_RS00525	COG1136	(ABC) transporter
DYD83_RS00525	COG0577	efflux transmembrane transporter activity
DYD83_RS00540	COG2091	lysine biosynthetic process via aminoadipic acid
DYD83_RS00565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DYD83_RS00600	COG0318	PFAM AMP-dependent synthetase and ligase
DYD83_RS00620	COG2771	luxR family
DYD83_RS00625	COG3916	Acyl-homoserine-lactone synthase
DYD83_RS00675	COG3179	chitinase
DYD83_RS00685	COG1561	YicC-like family, N-terminal region
DYD83_RS00690	COG0583	DNA-binding transcription factor activity
DYD83_RS00700	COG0747	negative chemotaxis
DYD83_RS00705	COG0601	transmembrane transport
DYD83_RS00710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DYD83_RS00715	COG0444	Belongs to the ABC transporter superfamily
DYD83_RS00720	COG4608	Belongs to the ABC transporter superfamily
DYD83_RS00750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DYD83_RS00755	COG0601	transmembrane transport
DYD83_RS00760	COG0747	negative chemotaxis
DYD83_RS00765	COG4172	Belongs to the ABC transporter superfamily
DYD83_RS00770	COG4948	Mandelate Racemase Muconate Lactonizing
DYD83_RS00785	COG2149	membrane
DYD83_RS00790	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DYD83_RS00795	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DYD83_RS00800	COG1309	transcriptional regulator
DYD83_RS00805	COG0756	dUTP diphosphatase activity
DYD83_RS00810	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DYD83_RS00815	COG2003	Belongs to the UPF0758 family
DYD83_RS00830	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DYD83_RS00835	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DYD83_RS00845	COG1519	Transferase
DYD83_RS00850	COG0438	transferase activity, transferring glycosyl groups
DYD83_RS00870	COG0859	PFAM glycosyl transferase family 9
DYD83_RS00875	COG0859	PFAM glycosyl transferase family 9
DYD83_RS00880	COG0859	PFAM glycosyl transferase family 9
DYD83_RS00885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DYD83_RS00890	COG0156	8-amino-7-oxononanoate synthase activity
DYD83_RS00895	COG1063	alcohol dehydrogenase
DYD83_RS00900	COG2861	carbohydrate metabolic process
DYD83_RS00905	COG4942	peptidase
DYD83_RS00910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DYD83_RS00915	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
DYD83_RS00920	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DYD83_RS00925	COG1045	serine acetyltransferase
DYD83_RS00940	COG0583	DNA-binding transcription factor activity
DYD83_RS00945	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DYD83_RS00950	COG0412	Dienelactone hydrolase
DYD83_RS00955	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
DYD83_RS00965	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DYD83_RS00970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DYD83_RS00975	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DYD83_RS00980	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DYD83_RS00985	COG0165	Argininosuccinate lyase
DYD83_RS00990	COG1322	Protein conserved in bacteria
DYD83_RS00995	COG2226	methyltransferase
DYD83_RS01000	COG3165	ubiquinone biosynthetic process from chorismate
DYD83_RS01005	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DYD83_RS01010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DYD83_RS01020	COG0805	protein transport
DYD83_RS01025	COG0084	hydrolase, TatD family'
DYD83_RS01040	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DYD83_RS01050	COG0640	Transcriptional regulator
DYD83_RS01065	COG0183	Belongs to the thiolase family
DYD83_RS01070	COG1250	3-hydroxyacyl-CoA dehydrogenase
DYD83_RS01070	COG1024	Enoyl-CoA hydratase
DYD83_RS01075	COG0006	proline dipeptidase activity
DYD83_RS01080	COG1739	Uncharacterized protein family UPF0029
DYD83_RS01085	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DYD83_RS01125	COG1072	(Pantothenic acid kinase))
DYD83_RS01155	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DYD83_RS01165	COG0250	Participates in transcription elongation, termination and antitermination
DYD83_RS01195	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DYD83_RS01215	COG5457	Domain of unknown function (DUF1127)
DYD83_RS01220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DYD83_RS01235	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DYD83_RS01240	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
DYD83_RS01260	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DYD83_RS01265	COG2022	thiamine diphosphate biosynthetic process
DYD83_RS01270	COG2104	thiamine diphosphate biosynthetic process
DYD83_RS01275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DYD83_RS01280	COG0352	thiamine-phosphate diphosphorylase activity
DYD83_RS01285	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DYD83_RS01290	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
DYD83_RS01295	COG2816	NAD+ diphosphatase activity
DYD83_RS01300	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DYD83_RS01305	COG1515	deoxyribonuclease V activity
DYD83_RS01325	COG0151	Belongs to the GarS family
DYD83_RS01330	COG0138	bifunctional purine biosynthesis protein purh
DYD83_RS01360	COG1126	abc transporter atp-binding protein
DYD83_RS01365	COG0765	amino acid transport
DYD83_RS01370	COG4597	amino acid ABC transporter
DYD83_RS01375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYD83_RS01380	COG0504	CTP synthase activity
DYD83_RS01385	COG0765	amino acid transport
DYD83_RS01390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYD83_RS01400	COG4221	oxidoreductase activity
DYD83_RS01415	COG4221	oxidoreductase activity
DYD83_RS01420	COG1064	alcohol dehydrogenase
DYD83_RS01425	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DYD83_RS01435	COG2264	protein methyltransferase activity
DYD83_RS01440	COG4145	pantothenate transmembrane transporter activity
DYD83_RS01445	COG3924	membrane
DYD83_RS01450	COG0439	Biotin carboxylase
DYD83_RS01455	COG0511	ligase activity, forming carbon-carbon bonds
DYD83_RS01460	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DYD83_RS01465	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
DYD83_RS01470	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DYD83_RS01475	COG0604	alcohol dehydrogenase
DYD83_RS01480	COG2199	diguanylate cyclase activity
DYD83_RS01480	COG2200	EAL domain
DYD83_RS01485	COG1077	Cell shape determining protein MreB Mrl
DYD83_RS01490	COG1792	Involved in formation and maintenance of cell shape
DYD83_RS01495	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DYD83_RS01500	COG0424	maF-like protein
DYD83_RS01510	COG3164	Protein of unknown function
DYD83_RS01515	COG0312	modulator of DNA gyrase
DYD83_RS01520	COG0583	DNA-binding transcription factor activity
DYD83_RS01530	COG1566	PFAM secretion protein HlyD family protein
DYD83_RS01535	COG1289	transmembrane transporter activity
DYD83_RS01545	COG1280	lysine exporter protein (LysE YggA)
DYD83_RS01550	COG3028	Belongs to the UPF0307 family
DYD83_RS01555	COG0312	modulator of DNA gyrase
DYD83_RS01560	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DYD83_RS01565	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DYD83_RS01570	COG1660	Displays ATPase and GTPase activities
DYD83_RS01585	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DYD83_RS01590	COG1137	ATPase activity
DYD83_RS01595	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DYD83_RS01600	COG3117	lipopolysaccharide transmembrane transporter activity
DYD83_RS01605	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DYD83_RS01610	COG0517	IMP dehydrogenase activity
DYD83_RS01610	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DYD83_RS01615	COG0530	calcium, potassium:sodium antiporter activity
DYD83_RS01620	COG1127	ABC transporter
DYD83_RS01625	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DYD83_RS01630	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DYD83_RS01635	COG2854	intermembrane phospholipid transfer
DYD83_RS01640	COG3113	response to antibiotic
DYD83_RS01645	COG5007	Belongs to the BolA IbaG family
DYD83_RS01650	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DYD83_RS01655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DYD83_RS01660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DYD83_RS01665	COG3105	Protein conserved in bacteria
DYD83_RS01670	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DYD83_RS01685	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DYD83_RS01690	COG0625	glutathione transferase activity
DYD83_RS01695	COG2969	positive regulation of protein catabolic process
DYD83_RS01705	COG0493	'glutamate synthase
DYD83_RS01710	COG0067	glutamate synthase
DYD83_RS01710	COG0069	glutamate synthase activity
DYD83_RS01710	COG0070	glutamate synthase
DYD83_RS01715	COG1242	4 iron, 4 sulfur cluster binding
DYD83_RS01720	COG0784	Response regulator, receiver
DYD83_RS01720	COG2198	Histidine kinase
DYD83_RS01720	COG5002	protein histidine kinase activity
DYD83_RS01725	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
DYD83_RS01730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DYD83_RS01740	COG2823	Periplasmic or secreted lipoprotein
DYD83_RS01745	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DYD83_RS01750	COG0792	nuclease activity
DYD83_RS01755	COG3107	peptidoglycan biosynthetic process
DYD83_RS01760	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DYD83_RS01770	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DYD83_RS01775	COG3384	dioxygenase
DYD83_RS01780	COG0754	glutathionylspermidine amidase activity
DYD83_RS01785	COG5463	Belongs to the UPF0441 family
DYD83_RS01790	COG1538	Outer membrane efflux protein
DYD83_RS01795	COG0494	nUDIX hydrolase
DYD83_RS01800	COG3151	Protein conserved in bacteria
DYD83_RS01805	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DYD83_RS01810	COG3150	esterase
DYD83_RS01820	COG0583	DNA-binding transcription factor activity
DYD83_RS01825	COG2249	NAD(P)H dehydrogenase (quinone) activity
DYD83_RS01835	COG0204	Acyl-transferase
DYD83_RS01840	COG2132	Multicopper oxidase
DYD83_RS01845	COG0656	L-ascorbic acid biosynthetic process
DYD83_RS01850	COG1979	alcohol dehydrogenase
DYD83_RS01855	COG0778	Nitroreductase
DYD83_RS01860	COG2207	Transcriptional regulator
DYD83_RS01870	COG0626	cystathionine gamma-synthase activity
DYD83_RS01880	COG0848	biopolymer transport protein
DYD83_RS01935	COG1857	crispr-associated protein
DYD83_RS01950	COG1518	maintenance of DNA repeat elements
DYD83_RS01955	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DYD83_RS01960	COG0840	transmembrane signaling receptor activity
DYD83_RS01965	COG3311	Transcriptional regulator
DYD83_RS01970	COG1569	PIN domain
DYD83_RS01985	COG1328	CTP reductase activity
DYD83_RS01995	COG4166	transmembrane transport
DYD83_RS02000	COG0601	transmembrane transport
DYD83_RS02005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DYD83_RS02050	COG2308	Evidence 4 Homologs of previously reported genes of
DYD83_RS02070	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
DYD83_RS02075	COG0540	Belongs to the ATCase OTCase family
DYD83_RS02080	COG2731	YhcH YjgK YiaL family protein
DYD83_RS02090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DYD83_RS02090	COG1263	PTS System
DYD83_RS02090	COG2190	(PTS) system
DYD83_RS02095	COG2723	6-phospho-beta-galactosidase activity
DYD83_RS02100	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DYD83_RS02115	COG1396	sequence-specific DNA binding
DYD83_RS02120	COG0454	-acetyltransferase
DYD83_RS02125	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DYD83_RS02130	COG0840	transmembrane signaling receptor activity
DYD83_RS02135	COG0525	valine-tRNA ligase activity
DYD83_RS02140	COG2927	DNA polymerase III (CHI subunit)
DYD83_RS02145	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DYD83_RS02150	COG0795	lipopolysaccharide-transporting ATPase activity
DYD83_RS02155	COG0795	lipopolysaccharide-transporting ATPase activity
DYD83_RS02165	COG0582	viral genome integration into host DNA
DYD83_RS02195	COG3423	Transcriptional regulator
DYD83_RS02225	COG2226	methyltransferase
DYD83_RS02250	COG3547	Transposase (IS116 IS110 IS902 family)
DYD83_RS02270	COG1349	DNA-binding transcription factor activity
DYD83_RS02280	COG1129	ABC transporter
DYD83_RS02285	COG1172	Belongs to the binding-protein-dependent transport system permease family
DYD83_RS02290	COG1172	Belongs to the binding-protein-dependent transport system permease family
DYD83_RS02295	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DYD83_RS02305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DYD83_RS02320	COG2814	Major facilitator Superfamily
DYD83_RS02330	COG0747	negative chemotaxis
DYD83_RS02335	COG0601	transmembrane transport
DYD83_RS02345	COG0444	Belongs to the ABC transporter superfamily
DYD83_RS02350	COG4608	Belongs to the ABC transporter superfamily
DYD83_RS02360	COG0583	DNA-binding transcription factor activity
DYD83_RS02380	COG1605	Chorismate mutase
DYD83_RS02390	COG1418	mRNA catabolic process
DYD83_RS02395	COG0659	secondary active sulfate transmembrane transporter activity
DYD83_RS02400	COG0288	reversible hydration of carbon dioxide
DYD83_RS02405	COG1414	Transcriptional regulator
DYD83_RS02410	COG0840	transmembrane signaling receptor activity
DYD83_RS02420	COG0235	Class ii aldolase
DYD83_RS02425	COG4806	L-rhamnose isomerase
DYD83_RS02430	COG1070	Carbohydrate kinase
DYD83_RS02435	COG2169	Transcriptional regulator
DYD83_RS02435	COG1917	Cupin 2, conserved barrel domain protein
DYD83_RS02440	COG4977	sequence-specific DNA binding
DYD83_RS02440	COG1917	Cupin 2, conserved barrel domain protein
DYD83_RS02455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DYD83_RS02465	COG0747	negative chemotaxis
DYD83_RS02475	COG3477	response to acidic pH
DYD83_RS02485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DYD83_RS02490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DYD83_RS02495	COG0006	proline dipeptidase activity
DYD83_RS02505	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DYD83_RS02515	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DYD83_RS02530	COG0560	Phosphoserine phosphatase
DYD83_RS02535	COG3726	membrane protein affecting hemolysin expression
DYD83_RS02540	COG4106	trans-aconitate 2-methyltransferase activity
DYD83_RS02555	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DYD83_RS02560	COG2823	Periplasmic or secreted lipoprotein
DYD83_RS02575	COG0084	hydrolase, TatD family'
DYD83_RS02590	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
DYD83_RS02595	COG0840	transmembrane signaling receptor activity
DYD83_RS02600	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
DYD83_RS02620	COG1473	amidohydrolase
DYD83_RS02630	COG1120	ATPase activity
DYD83_RS02640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DYD83_RS02650	COG3634	alkyl hydroperoxide reductase activity
DYD83_RS02665	COG2351	hydroxyisourate hydrolase activity
DYD83_RS02700	COG0789	Transcriptional regulator
DYD83_RS02705	COG1609	Transcriptional regulator
DYD83_RS02750	COG0297	glycogen (starch) synthase activity
DYD83_RS02755	COG0438	transferase activity, transferring glycosyl groups
DYD83_RS02755	COG0297	glycogen (starch) synthase activity
DYD83_RS02770	COG1045	serine acetyltransferase
DYD83_RS02790	COG3547	Transposase (IS116 IS110 IS902 family)
DYD83_RS02855	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DYD83_RS02865	COG0629	single-stranded DNA binding
DYD83_RS02920	COG0741	lytic transglycosylase activity
DYD83_RS03135	COG2003	Belongs to the UPF0758 family
DYD83_RS03225	COG1309	transcriptional regulator
DYD83_RS03230	COG4232	protein-disulfide reductase activity
DYD83_RS03235	COG1324	tolerance protein
DYD83_RS03240	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DYD83_RS03255	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DYD83_RS03260	COG0459	protein refolding
DYD83_RS03265	COG3161	chorismate lyase activity
DYD83_RS03270	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DYD83_RS03275	COG2937	Belongs to the GPAT DAPAT family
DYD83_RS03280	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DYD83_RS03285	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DYD83_RS03290	COG0735	belongs to the Fur family
DYD83_RS03295	COG1741	Belongs to the pirin family
DYD83_RS03300	COG0583	DNA-binding transcription factor activity
DYD83_RS03305	COG0435	Glutathione S-transferase
DYD83_RS03310	COG2259	Doxx family
DYD83_RS03320	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
DYD83_RS03325	COG4575	ribosome binding
DYD83_RS03335	COG0586	Pfam SNARE associated Golgi protein
DYD83_RS03345	COG2271	Major facilitator Superfamily
DYD83_RS03350	COG1904	glucuronate isomerase
DYD83_RS03355	COG0246	Mannitol dehydrogenase
DYD83_RS03360	COG2721	sulfolactate sulfo-lyase activity
DYD83_RS03370	COG0861	Integral membrane protein TerC family
DYD83_RS03375	COG2813	Specifically methylates the guanine in position
DYD83_RS03390	COG2197	response regulator
DYD83_RS03400	COG2271	Major facilitator Superfamily
DYD83_RS03410	COG3678	ATP-independent chaperone mediated protein folding
DYD83_RS03415	COG1477	protein flavinylation
DYD83_RS03440	COG0667	Aldo Keto reductase
DYD83_RS03445	COG0300	oxidoreductase activity
DYD83_RS03450	COG0300	oxidoreductase activity
DYD83_RS03470	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DYD83_RS03475	COG0358	DNA primase activity
DYD83_RS03480	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DYD83_RS03485	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DYD83_RS03490	COG1438	arginine binding
DYD83_RS03500	COG3423	Transcriptional regulator
DYD83_RS03515	COG0142	geranyltranstransferase activity
DYD83_RS03520	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DYD83_RS03530	COG0697	spore germination
DYD83_RS03535	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DYD83_RS03540	COG2027	D-alanyl-D-alanine carboxypeptidase
DYD83_RS03550	COG1534	Rna-binding protein
DYD83_RS03555	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DYD83_RS03560	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DYD83_RS03565	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DYD83_RS03570	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DYD83_RS03575	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DYD83_RS03595	COG0195	Participates in both transcription termination and antitermination
DYD83_RS03600	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DYD83_RS03605	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DYD83_RS03610	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DYD83_RS03615	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DYD83_RS03620	COG1185	polyribonucleotide nucleotidyltransferase activity
DYD83_RS03635	COG0513	Belongs to the DEAD box helicase family
DYD83_RS03640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DYD83_RS03645	COG0826	peptidase U32
DYD83_RS03650	COG0826	peptidase U32
DYD83_RS03655	COG3154	lipid carrier protein
DYD83_RS03660	COG3153	acetyltransferase
DYD83_RS03670	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DYD83_RS03675	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DYD83_RS03680	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DYD83_RS03685	COG0813	purine-nucleoside phosphorylase activity
DYD83_RS03690	COG4178	(ABC) transporter
DYD83_RS03705	COG1595	DNA-templated transcription, initiation
DYD83_RS03715	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
DYD83_RS03720	COG2813	Specifically methylates the guanine in position
DYD83_RS03725	COG0667	Aldo Keto reductase
DYD83_RS03730	COG0583	DNA-binding transcription factor activity
DYD83_RS03770	COG1454	alcohol dehydrogenase
DYD83_RS03775	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DYD83_RS03780	COG0509	glycine decarboxylation via glycine cleavage system
DYD83_RS03785	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DYD83_RS03785	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DYD83_RS03790	COG1280	lysine exporter protein (LysE YggA)
DYD83_RS03800	COG1272	protein, Hemolysin III
DYD83_RS03805	COG0354	folic acid binding
DYD83_RS03810	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DYD83_RS03820	COG0716	FMN binding
DYD83_RS03825	COG0477	Major facilitator Superfamily
DYD83_RS03830	COG4974	Belongs to the 'phage' integrase family
DYD83_RS03835	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DYD83_RS03840	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DYD83_RS03890	COG2020	methyltransferase activity
DYD83_RS03900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DYD83_RS03925	COG0671	phosphoesterase, PA-phosphatase related
DYD83_RS03930	COG1733	regulation of RNA biosynthetic process
DYD83_RS03945	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DYD83_RS03960	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DYD83_RS03965	COG0395	ABC-type sugar transport system, permease component
DYD83_RS03970	COG1175	transmembrane transport
DYD83_RS03980	COG1560	Kdo2-lipid A biosynthetic process
DYD83_RS03985	COG2252	PERMEase
DYD83_RS03990	COG0025	NhaP-type Na H and K H
DYD83_RS03995	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DYD83_RS04000	COG3162	membrane
DYD83_RS04005	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DYD83_RS04015	COG4774	siderophore transport
DYD83_RS04020	COG4948	Mandelate Racemase Muconate Lactonizing
DYD83_RS04025	COG0747	negative chemotaxis
DYD83_RS04030	COG0601	transmembrane transport
DYD83_RS04035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DYD83_RS04040	COG0444	Belongs to the ABC transporter superfamily
DYD83_RS04045	COG4608	Belongs to the ABC transporter superfamily
DYD83_RS04055	COG3712	iron ion homeostasis
DYD83_RS04095	COG0246	Mannitol dehydrogenase
DYD83_RS04100	COG2814	Major facilitator Superfamily
DYD83_RS04110	COG1846	Transcriptional regulator
DYD83_RS04115	COG1376	ErfK ybiS ycfS ynhG family protein
DYD83_RS04120	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DYD83_RS04120	COG0674	pyruvate-flavodoxin oxidoreductase activity
DYD83_RS04120	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DYD83_RS04120	COG1013	pyruvate-flavodoxin oxidoreductase activity
DYD83_RS04150	COG2211	Major facilitator Superfamily
DYD83_RS04180	COG1181	Belongs to the D-alanine--D-alanine ligase family
DYD83_RS04205	COG2814	Major facilitator Superfamily
DYD83_RS04210	COG0583	DNA-binding transcription factor activity
DYD83_RS04230	COG3962	Belongs to the TPP enzyme family
DYD83_RS04235	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
DYD83_RS04275	COG0673	inositol 2-dehydrogenase activity
DYD83_RS04290	COG1172	Belongs to the binding-protein-dependent transport system permease family
DYD83_RS04300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DYD83_RS04310	COG3718	enzyme involved in inositol metabolism
DYD83_RS04315	COG2951	lytic endotransglycosylase activity
DYD83_RS04320	COG0583	DNA-binding transcription factor activity
DYD83_RS04325	COG2271	Major facilitator Superfamily
DYD83_RS04330	COG4948	Mandelate Racemase Muconate Lactonizing
DYD83_RS04385	COG3547	Transposase (IS116 IS110 IS902 family)
DYD83_RS04405	COG2867	negative regulation of translational initiation
DYD83_RS04410	COG2914	Belongs to the UPF0125 (RnfH) family
DYD83_RS04420	COG0497	DNA recombination
DYD83_RS04425	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DYD83_RS04430	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DYD83_RS04435	COG1914	H( )-stimulated, divalent metal cation uptake system
DYD83_RS04440	COG0494	nUDIX hydrolase
DYD83_RS04445	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DYD83_RS04455	COG1671	Belongs to the UPF0178 family
DYD83_RS04460	COG0408	coproporphyrinogen oxidase activity
DYD83_RS04465	COG0456	acetyltransferase
DYD83_RS04470	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
DYD83_RS04475	COG4771	TonB-dependent receptor
DYD83_RS04480	COG0612	Peptidase, M16
DYD83_RS04485	COG4178	(ABC) transporter
DYD83_RS04520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DYD83_RS04525	COG3118	belongs to the thioredoxin family
DYD83_RS04530	COG1902	pentaerythritol trinitrate reductase activity
DYD83_RS04535	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DYD83_RS04540	COG1028	Short-chain dehydrogenase reductase Sdr
DYD83_RS04545	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DYD83_RS04570	COG3423	Transcriptional regulator
DYD83_RS04585	COG2837	iron assimilation
DYD83_RS04595	COG1136	(ABC) transporter
DYD83_RS04595	COG0577	efflux transmembrane transporter activity
DYD83_RS04600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DYD83_RS04605	COG0745	RESPONSE REGULATOR receiver
DYD83_RS04610	COG2205	protein histidine kinase activity
DYD83_RS04615	COG2190	(PTS) system
DYD83_RS04625	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DYD83_RS04630	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DYD83_RS04635	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
DYD83_RS04640	COG3115	cell septum assembly
DYD83_RS04645	COG0531	amino acid
DYD83_RS04655	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DYD83_RS04665	COG0446	pyridine nucleotide-disulphide oxidoreductase
DYD83_RS04670	COG0426	domain, Protein
DYD83_RS04670	COG1773	rubredoxin
DYD83_RS04675	COG3604	Transcriptional regulator
DYD83_RS04680	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DYD83_RS04680	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DYD83_RS04705	COG1053	succinate dehydrogenase
DYD83_RS04710	COG3976	FMN-binding domain protein
DYD83_RS04710	COG0431	NADPH-dependent FMN reductase
DYD83_RS04710	COG1053	succinate dehydrogenase
DYD83_RS04715	COG0477	Major facilitator Superfamily
DYD83_RS04720	COG3301	Polysulphide reductase, NrfD
DYD83_RS04725	COG0437	4 iron, 4 sulfur cluster binding
DYD83_RS04740	COG1609	Transcriptional regulator
DYD83_RS04745	COG1234	tRNA 3'-trailer cleavage
DYD83_RS04760	COG1175	transmembrane transport
DYD83_RS04765	COG1653	transport
DYD83_RS04780	COG0473	3-isopropylmalate dehydrogenase activity
DYD83_RS04785	COG0583	DNA-binding transcription factor activity
DYD83_RS04790	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DYD83_RS04790	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DYD83_RS04810	COG2862	Uncharacterized protein family, UPF0114
DYD83_RS04850	COG0745	RESPONSE REGULATOR receiver
DYD83_RS04855	COG5002	protein histidine kinase activity
DYD83_RS04865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DYD83_RS04875	COG1733	regulation of RNA biosynthetic process
DYD83_RS04915	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
DYD83_RS04920	COG0577	efflux transmembrane transporter activity
DYD83_RS04920	COG1136	(ABC) transporter
DYD83_RS04930	COG1136	(ABC) transporter
DYD83_RS04930	COG0577	efflux transmembrane transporter activity
DYD83_RS04975	COG0534	Mate efflux family protein
DYD83_RS05000	COG4221	oxidoreductase activity
DYD83_RS05035	COG3423	Transcriptional regulator
DYD83_RS05060	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DYD83_RS05070	COG1002	Type II restriction enzyme, methylase subunits
DYD83_RS05075	COG1061	Type III restriction enzyme res subunit
DYD83_RS05080	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DYD83_RS05110	COG0582	viral genome integration into host DNA
DYD83_RS05120	COG1982	Orn Lys Arg decarboxylase major
DYD83_RS05130	COG0741	lytic transglycosylase activity
DYD83_RS05135	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
DYD83_RS05145	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DYD83_RS05150	COG3171	Protein conserved in bacteria
DYD83_RS05165	COG0667	Aldo Keto reductase
DYD83_RS05175	COG0861	Integral membrane protein TerC family
DYD83_RS05180	COG3066	DNA modification
DYD83_RS05185	COG0494	nUDIX hydrolase
DYD83_RS05195	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DYD83_RS05200	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DYD83_RS05205	COG2165	general secretion pathway protein
DYD83_RS05210	COG4795	General secretion pathway protein
DYD83_RS05225	COG1025	Belongs to the peptidase M16 family
DYD83_RS05230	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DYD83_RS05230	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DYD83_RS05235	COG0860	N-Acetylmuramoyl-L-alanine amidase
DYD83_RS05250	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
DYD83_RS05265	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DYD83_RS05275	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DYD83_RS05280	COG2166	iron-sulfur cluster assembly
DYD83_RS05285	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DYD83_RS05295	COG0583	DNA-binding transcription factor activity
DYD83_RS05300	COG2363	Small membrane protein
DYD83_RS05305	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
DYD83_RS05310	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DYD83_RS05315	COG1611	Belongs to the LOG family
DYD83_RS05345	COG2171	N-acyltransferase activity
DYD83_RS05350	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DYD83_RS05365	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DYD83_RS05370	COG0528	UMP kinase activity
DYD83_RS05375	COG0233	cytoplasmic translational termination
DYD83_RS05380	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DYD83_RS05385	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DYD83_RS05390	COG0575	Belongs to the CDS family
DYD83_RS05395	COG0750	zinc metalloprotease
DYD83_RS05400	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DYD83_RS05405	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
DYD83_RS05410	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DYD83_RS05415	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DYD83_RS05420	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DYD83_RS05425	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DYD83_RS05430	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DYD83_RS05435	COG0587	DNA-directed DNA polymerase activity
DYD83_RS05440	COG0825	malonyl-CoA metabolic process
DYD83_RS05445	COG0346	lactoylglutathione lyase activity
DYD83_RS05450	COG0037	tRNA processing
DYD83_RS05455	COG4568	rho-dependent transcription termination
DYD83_RS05465	COG4681	YaeQ
DYD83_RS05470	COG3015	lipoprotein NlpE involved in copper resistance
DYD83_RS05475	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DYD83_RS05490	COG1733	regulation of RNA biosynthetic process
DYD83_RS05535	COG1881	PFAM PEBP family protein
DYD83_RS05565	COG2192	nodulation
DYD83_RS05590	COG2423	ornithine cyclodeaminase activity
DYD83_RS05600	COG0583	DNA-binding transcription factor activity
DYD83_RS05615	COG0546	phosphoglycolate phosphatase activity
DYD83_RS05630	COG2824	Alkylphosphonate utilization operon protein PhnA
DYD83_RS05635	COG3706	GGDEF domain
DYD83_RS05660	COG0583	DNA-binding transcription factor activity
DYD83_RS05685	COG0583	DNA-binding transcription factor activity
DYD83_RS05700	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DYD83_RS05705	COG4615	Cyclic peptide transporter
DYD83_RS05720	COG3123	guanosine phosphorylase activity
DYD83_RS05725	COG0840	transmembrane signaling receptor activity
DYD83_RS05735	COG2974	May be involved in recombination
DYD83_RS05740	COG1940	carbohydrate kinase activity
DYD83_RS05745	COG0419	ATPase involved in DNA repair
DYD83_RS05750	COG0420	3'-5' exonuclease activity
DYD83_RS05760	COG5002	protein histidine kinase activity
DYD83_RS05770	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DYD83_RS05785	COG0450	alkyl hydroperoxide reductase
DYD83_RS05790	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
DYD83_RS05795	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DYD83_RS05800	COG0343	queuine tRNA-ribosyltransferase activity
DYD83_RS05805	COG1862	Preprotein translocase
DYD83_RS05810	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DYD83_RS05815	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DYD83_RS05820	COG4238	major outer membrane lipoprotein
DYD83_RS05825	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DYD83_RS05830	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DYD83_RS05835	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DYD83_RS05835	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DYD83_RS05840	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DYD83_RS05845	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DYD83_RS05850	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DYD83_RS05855	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DYD83_RS05860	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DYD83_RS05865	COG0142	geranyltranstransferase activity
DYD83_RS05870	COG1722	exodeoxyribonuclease VII activity
DYD83_RS05875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DYD83_RS05875	COG0301	tRNA thio-modification
DYD83_RS05880	COG0693	protein deglycase activity
DYD83_RS05885	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DYD83_RS05890	COG1666	GTP binding
DYD83_RS05905	COG2814	Major facilitator Superfamily
DYD83_RS05925	COG0109	protoheme IX farnesyltransferase activity
DYD83_RS05930	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DYD83_RS05935	COG1845	cytochrome c oxidase, subunit III
DYD83_RS05940	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DYD83_RS05945	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DYD83_RS05950	COG2223	nitrite transmembrane transporter activity
DYD83_RS05955	COG3056	Lipoprotein
DYD83_RS05960	COG0271	Belongs to the BolA IbaG family
DYD83_RS05965	COG0544	peptidyl-prolyl cis-trans isomerase activity
DYD83_RS05970	COG0740	serine-type endopeptidase activity
DYD83_RS05975	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DYD83_RS05980	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DYD83_RS05985	COG0776	regulation of translation
DYD83_RS05990	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DYD83_RS05995	COG1555	photosystem II stabilization
DYD83_RS06000	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DYD83_RS06010	COG1522	sequence-specific DNA binding
DYD83_RS06015	COG1132	(ABC) transporter
DYD83_RS06020	COG1132	(ABC) transporter
DYD83_RS06025	COG0347	Belongs to the P(II) protein family
DYD83_RS06030	COG0004	ammonium transporteR
DYD83_RS06035	COG1946	Acyl-CoA thioesterase
DYD83_RS06040	COG3126	Type III secretion system lipoprotein chaperone (YscW)
DYD83_RS06045	COG3695	enzyme binding
DYD83_RS06065	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DYD83_RS06070	COG0254	rRNA binding
DYD83_RS06075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DYD83_RS06080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DYD83_RS06085	COG1309	transcriptional regulator
DYD83_RS06090	COG3264	Mechanosensitive ion channel
DYD83_RS06090	COG1196	nuclear chromosome segregation
DYD83_RS06110	COG2832	Protein of unknown function (DUF454)
DYD83_RS06115	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DYD83_RS06125	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DYD83_RS06130	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DYD83_RS06135	COG0326	Molecular chaperone. Has ATPase activity
DYD83_RS06140	COG0563	adenylate kinase activity
DYD83_RS06145	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DYD83_RS06150	COG4651	solute:proton antiporter activity
DYD83_RS06150	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DYD83_RS06155	COG0737	Belongs to the 5'-nucleotidase family
DYD83_RS06170	COG0840	transmembrane signaling receptor activity
DYD83_RS06180	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DYD83_RS06185	COG3735	TraB family
DYD83_RS06190	COG2217	Heavy metal translocating P-type atpase
DYD83_RS06195	COG0789	Transcriptional regulator
DYD83_RS06200	COG1585	Membrane protein implicated in regulation of membrane protease activity
DYD83_RS06205	COG0330	HflC and HflK could
DYD83_RS06210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DYD83_RS06220	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DYD83_RS06225	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DYD83_RS06235	COG2205	protein histidine kinase activity
DYD83_RS06235	COG0784	Response regulator, receiver
DYD83_RS06245	COG0642	Histidine kinase
DYD83_RS06245	COG2198	Histidine kinase
DYD83_RS06250	COG2223	nitrite transmembrane transporter activity
DYD83_RS06255	COG1169	isochorismate synthase
DYD83_RS06260	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DYD83_RS06265	COG0596	Alpha beta hydrolase
DYD83_RS06275	COG1441	menaquinone biosynthetic process
DYD83_RS06295	COG3118	belongs to the thioredoxin family
DYD83_RS06300	COG0300	oxidoreductase activity
DYD83_RS06305	COG2755	lipolytic protein G-D-S-L family
DYD83_RS06310	COG4181	ATPase activity
DYD83_RS06315	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
DYD83_RS06320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DYD83_RS06330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DYD83_RS06335	COG0765	amino acid transport
DYD83_RS06340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYD83_RS06365	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DYD83_RS06370	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DYD83_RS06375	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DYD83_RS06380	COG2233	PERMEase
DYD83_RS06385	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DYD83_RS06390	COG1393	Belongs to the ArsC family
DYD83_RS06395	COG4783	chaperone-mediated protein folding
DYD83_RS06400	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DYD83_RS06405	COG2716	regulation of RNA biosynthetic process
DYD83_RS06415	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DYD83_RS06420	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DYD83_RS06425	COG2707	UPF0756 membrane protein
DYD83_RS06430	COG1444	tRNA N-acetyltransferase activity
DYD83_RS06435	COG0400	carboxylic ester hydrolase activity
DYD83_RS06445	COG1876	peptidase activity
DYD83_RS06450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DYD83_RS06455	COG1393	Belongs to the ArsC family
DYD83_RS06465	COG1794	racemase activity, acting on amino acids and derivatives
DYD83_RS06475	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DYD83_RS06480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DYD83_RS06485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DYD83_RS06490	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DYD83_RS06495	COG0321	lipoyl(octanoyl) transferase activity
DYD83_RS06500	COG2921	Belongs to the UPF0250 family
DYD83_RS06505	COG1686	Belongs to the peptidase S11 family
DYD83_RS06510	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DYD83_RS06515	COG0772	Belongs to the SEDS family
DYD83_RS06520	COG0768	penicillin binding
DYD83_RS06525	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DYD83_RS06530	COG0799	negative regulation of ribosome biogenesis
DYD83_RS06535	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DYD83_RS06540	COG1466	dna polymerase III delta subunit
DYD83_RS06545	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
DYD83_RS06550	COG0495	leucyl-tRNA aminoacylation
DYD83_RS06555	COG2888	peptidyl-tyrosine sulfation
DYD83_RS06565	COG1126	abc transporter atp-binding protein
DYD83_RS06570	COG0765	amino acid transport
DYD83_RS06575	COG0765	amino acid transport
DYD83_RS06585	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DYD83_RS06590	COG4535	Mg2 and Co2 transporter CorC
DYD83_RS06595	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DYD83_RS06600	COG1702	phosphate starvation-inducible protein PhoH
DYD83_RS06605	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DYD83_RS06610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DYD83_RS06650	COG0367	asparagine synthase
DYD83_RS06655	COG1846	Transcriptional regulator
DYD83_RS06655	COG1940	carbohydrate kinase activity
DYD83_RS06660	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DYD83_RS06665	COG0363	glucosamine-6-phosphate deaminase activity
DYD83_RS06670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DYD83_RS06670	COG2190	(PTS) system
DYD83_RS06670	COG1263	PTS System
DYD83_RS06675	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DYD83_RS06680	COG0735	belongs to the Fur family
DYD83_RS06685	COG0716	FMN binding
DYD83_RS06690	COG0840	transmembrane signaling receptor activity
DYD83_RS06700	COG0596	Alpha beta hydrolase
DYD83_RS06710	COG0033	Phosphoglucomutase
DYD83_RS06720	COG0745	RESPONSE REGULATOR receiver
DYD83_RS06725	COG2205	protein histidine kinase activity
DYD83_RS06730	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DYD83_RS06735	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DYD83_RS06740	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DYD83_RS06755	COG3272	Protein of unknown function (DUF1722)
DYD83_RS06760	COG0415	Belongs to the DNA photolyase family
DYD83_RS06765	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DYD83_RS06770	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DYD83_RS06775	COG1984	allophanate hydrolase subunit 2
DYD83_RS06780	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DYD83_RS06785	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DYD83_RS06790	COG0372	Belongs to the citrate synthase family
DYD83_RS06800	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DYD83_RS06805	COG1053	succinate dehydrogenase
DYD83_RS06810	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DYD83_RS06815	COG0567	Dehydrogenase, E1 component
DYD83_RS06820	COG0508	dehydrogenase complex catalyzes the overall conversion of
DYD83_RS06825	COG0045	succinate-CoA ligase (ADP-forming) activity
DYD83_RS06830	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DYD83_RS06835	COG1271	oxidase subunit
DYD83_RS06840	COG1294	oxidase, subunit
DYD83_RS06845	COG4890	Cyd operon protein YbgT
DYD83_RS06850	COG3790	cyd operon protein YbgE
DYD83_RS06855	COG0824	Thioesterase
DYD83_RS06860	COG0811	peptide transport
DYD83_RS06865	COG0848	biopolymer transport protein
DYD83_RS06870	COG3064	Membrane
DYD83_RS06875	COG0823	Involved in the tonB-independent uptake of proteins
DYD83_RS06880	COG2885	chlorophyll binding
DYD83_RS06885	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
DYD83_RS06910	COG1811	Na channel or pump
DYD83_RS06915	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DYD83_RS06925	COG1230	cation diffusion facilitator family transporter
DYD83_RS06930	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DYD83_RS06935	COG0588	phosphoglycerate mutase activity
DYD83_RS06940	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DYD83_RS06945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DYD83_RS06965	COG2017	converts alpha-aldose to the beta-anomer
DYD83_RS06975	COG1085	galactose-1-phosphate uridylyltransferase
DYD83_RS06980	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DYD83_RS06985	COG1119	ATPase activity
DYD83_RS06990	COG2005	Transcriptional regulator
DYD83_RS06990	COG3585	molybdate ion transport
DYD83_RS07000	COG0725	ABC transporter, periplasmic molybdate-binding protein
DYD83_RS07005	COG4149	molybdate abc transporter
DYD83_RS07010	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DYD83_RS07015	COG0561	phosphatase activity
DYD83_RS07020	COG2706	6-phosphogluconolactonase activity
DYD83_RS07045	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DYD83_RS07045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DYD83_RS07050	COG0489	protein tyrosine kinase activity
DYD83_RS07060	COG0717	Belongs to the dCTP deaminase family
DYD83_RS07065	COG2982	Protein involved in outer membrane biogenesis
DYD83_RS07070	COG1253	flavin adenine dinucleotide binding
DYD83_RS07120	COG1088	dTDP-glucose 4,6-dehydratase activity
DYD83_RS07140	COG1215	transferase activity, transferring glycosyl groups
DYD83_RS07145	COG2244	polysaccharide biosynthetic process
DYD83_RS07175	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DYD83_RS07200	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DYD83_RS07220	COG3706	GGDEF domain
DYD83_RS07240	COG2990	Protein conserved in bacteria
DYD83_RS07250	COG3720	iron ion transport
DYD83_RS07255	COG4558	Periplasmic binding protein
DYD83_RS07260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DYD83_RS07265	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DYD83_RS07275	COG2706	6-phosphogluconolactonase activity
DYD83_RS07280	COG0783	Belongs to the Dps family
DYD83_RS07285	COG2267	carboxylic ester hydrolase activity
DYD83_RS07305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DYD83_RS07310	COG0444	Belongs to the ABC transporter superfamily
DYD83_RS07315	COG4608	Belongs to the ABC transporter superfamily
DYD83_RS07330	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DYD83_RS07340	COG2214	Heat shock protein DnaJ domain protein
DYD83_RS07345	COG0443	Heat shock 70 kDa protein
DYD83_RS07355	COG3501	Rhs element vgr protein
DYD83_RS07420	COG3209	COG3209 Rhs family protein
DYD83_RS07435	COG3547	Transposase (IS116 IS110 IS902 family)
DYD83_RS07455	COG1473	amidohydrolase
DYD83_RS07515	COG3829	transcription factor binding
DYD83_RS07555	COG4948	Mandelate Racemase Muconate Lactonizing
DYD83_RS07565	COG3706	GGDEF domain
DYD83_RS07565	COG2203	Gaf domain
DYD83_RS07565	COG4251	negative regulation of phosphorylation
DYD83_RS07565	COG5001	Diguanylate cyclase
DYD83_RS07570	COG0672	)-iron permease
DYD83_RS07585	COG3813	Protein conserved in bacteria
DYD83_RS07590	COG0477	Major facilitator Superfamily
DYD83_RS07600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DYD83_RS07605	COG1136	(ABC) transporter
DYD83_RS07605	COG0577	efflux transmembrane transporter activity
DYD83_RS07625	COG0604	alcohol dehydrogenase
DYD83_RS07625	COG1028	Short-chain dehydrogenase reductase Sdr
DYD83_RS07625	COG3321	synthase
DYD83_RS07630	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DYD83_RS07630	COG2070	2-Nitropropane dioxygenase
DYD83_RS07635	COG1028	Short-chain dehydrogenase reductase Sdr
DYD83_RS07665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DYD83_RS07690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DYD83_RS07695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DYD83_RS07700	COG0745	RESPONSE REGULATOR receiver
DYD83_RS07725	COG0730	response to heat
DYD83_RS07730	COG0488	(ABC) transporter
DYD83_RS07735	COG1556	Lactate utilization protein
DYD83_RS07740	COG1139	Iron-sulfur cluster binding protein
DYD83_RS07745	COG0247	lactate metabolic process
DYD83_RS07750	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DYD83_RS07760	COG1346	cytolysis
DYD83_RS07770	COG4566	intracellular signal transduction
DYD83_RS07775	COG4191	Histidine kinase
DYD83_RS07780	COG1116	anion transmembrane transporter activity
DYD83_RS07785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DYD83_RS07790	COG1285	pathogenesis
DYD83_RS07795	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
DYD83_RS07800	COG0768	penicillin binding
DYD83_RS07805	COG2890	protein-(glutamine-N5) methyltransferase activity
DYD83_RS07810	COG0747	negative chemotaxis
DYD83_RS07815	COG0601	transmembrane transport
DYD83_RS07825	COG0444	Belongs to the ABC transporter superfamily
DYD83_RS07830	COG1124	(ABC) transporter
DYD83_RS07835	COG1846	Transcriptional regulator
DYD83_RS07840	COG1566	PFAM secretion protein HlyD family protein
DYD83_RS07845	COG2814	Major facilitator Superfamily
DYD83_RS07850	COG3708	Transcriptional regulator
DYD83_RS07850	COG2207	Transcriptional regulator
DYD83_RS07855	COG3961	Belongs to the TPP enzyme family
DYD83_RS07870	COG3615	Tellurite resistance protein tehB
DYD83_RS07880	COG2814	Major facilitator Superfamily
DYD83_RS07895	COG0697	spore germination
DYD83_RS07900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYD83_RS07910	COG1984	allophanate hydrolase subunit 2
DYD83_RS07915	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DYD83_RS07930	COG0436	Aminotransferase
DYD83_RS07945	COG4221	oxidoreductase activity
DYD83_RS07950	COG0765	amino acid transport
DYD83_RS07955	COG0765	amino acid transport
DYD83_RS07970	COG3250	beta-galactosidase activity
DYD83_RS07975	COG1609	Transcriptional regulator
DYD83_RS07985	COG0583	DNA-binding transcription factor activity
DYD83_RS07990	COG1301	dicarboxylic acid transport
DYD83_RS08000	COG3383	formate dehydrogenase (NAD+) activity
DYD83_RS08005	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DYD83_RS08020	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
DYD83_RS08030	COG3260	NADH ubiquinone oxidoreductase 20
DYD83_RS08035	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DYD83_RS08040	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
DYD83_RS08040	COG3261	NADH dehydrogenase
DYD83_RS08045	COG0651	ATP synthesis coupled electron transport
DYD83_RS08050	COG4237	Hydrogenase 4 membrane
DYD83_RS08055	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DYD83_RS08060	COG0650	Formate hydrogenlyase subunit 4
DYD83_RS08065	COG0651	ATP synthesis coupled electron transport
DYD83_RS08070	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DYD83_RS08075	COG0298	carbon dioxide binding
DYD83_RS08090	COG0697	spore germination
DYD83_RS08095	COG0583	DNA-binding transcription factor activity
DYD83_RS08100	COG1301	dicarboxylic acid transport
DYD83_RS08105	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DYD83_RS08115	COG0625	glutathione transferase activity
DYD83_RS08120	COG0625	glutathione transferase activity
DYD83_RS08130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DYD83_RS08145	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DYD83_RS08150	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DYD83_RS08160	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DYD83_RS08170	COG1012	belongs to the aldehyde dehydrogenase family
DYD83_RS08175	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DYD83_RS08210	COG3547	Transposase (IS116 IS110 IS902 family)
DYD83_RS08230	COG2188	Transcriptional regulator
DYD83_RS08235	COG3624	Phosphonate C-P lyase system protein PhnG
DYD83_RS08240	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
DYD83_RS08245	COG3626	phosphonate metabolism
DYD83_RS08250	COG3627	carbon phosphorus lyase activity
DYD83_RS08255	COG4107	phosphonate C-P lyase system protein PhnK
DYD83_RS08260	COG4778	phosphonate C-P lyase system protein PhnL
DYD83_RS08265	COG3454	Phosphonate metabolism
DYD83_RS08270	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
DYD83_RS08275	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DYD83_RS08285	COG0583	DNA-binding transcription factor activity
DYD83_RS08295	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
DYD83_RS08305	COG3639	organic phosphonate transmembrane transporter activity
DYD83_RS08315	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DYD83_RS08330	COG0019	diaminopimelate decarboxylase activity
DYD83_RS08335	COG2814	Major facilitator Superfamily
DYD83_RS08340	COG4264	IucA IucC family
DYD83_RS08350	COG4264	IucA IucC family
DYD83_RS08355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DYD83_RS08360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DYD83_RS08365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DYD83_RS08370	COG1120	ATPase activity
DYD83_RS08375	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DYD83_RS08380	COG1598	PFAM Uncharacterised protein family UPF0150
DYD83_RS08400	COG3383	formate dehydrogenase (NAD+) activity
DYD83_RS08400	COG0243	molybdopterin cofactor binding
DYD83_RS08405	COG0437	4 iron, 4 sulfur cluster binding
DYD83_RS08410	COG2864	formate dehydrogenase
DYD83_RS08425	COG2211	Major facilitator Superfamily
DYD83_RS08450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DYD83_RS08455	COG1473	amidohydrolase
DYD83_RS08460	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DYD83_RS08475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DYD83_RS08480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DYD83_RS08490	COG2199	diguanylate cyclase activity
DYD83_RS08495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DYD83_RS08515	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DYD83_RS08540	COG3416	Protein conserved in bacteria
DYD83_RS08555	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DYD83_RS08560	COG2011	ABC-type metal ion transport system permease component
DYD83_RS08620	COG4166	transmembrane transport
DYD83_RS08625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DYD83_RS08630	COG1957	nucleoside hydrolase
DYD83_RS08635	COG1957	nucleoside hydrolase
DYD83_RS08640	COG0601	transmembrane transport
DYD83_RS08660	COG0174	glutamine synthetase
DYD83_RS08675	COG2964	Protein conserved in bacteria
DYD83_RS08685	COG0835	chemotaxis
DYD83_RS08685	COG0784	Response regulator, receiver
DYD83_RS08715	COG0679	Auxin Efflux Carrier
DYD83_RS08725	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DYD83_RS08740	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DYD83_RS08745	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DYD83_RS08750	COG1121	(ABC) transporter
DYD83_RS08755	COG0803	Belongs to the bacterial solute-binding protein 9 family
DYD83_RS08765	COG1979	alcohol dehydrogenase
DYD83_RS08770	COG2207	Transcriptional regulator
DYD83_RS08785	COG3228	Belongs to the MtfA family
DYD83_RS08805	COG0401	homolog of Blt101
DYD83_RS08815	COG0463	Glycosyl transferase, family 2
DYD83_RS08815	COG0457	Tetratricopeptide repeat
DYD83_RS08825	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DYD83_RS08830	COG0303	'Molybdopterin
DYD83_RS08835	COG0281	malic enzyme
DYD83_RS08840	COG0295	cytidine deaminase activity
DYD83_RS08850	COG1346	cytolysis
DYD83_RS08855	COG1380	Effector of murein hydrolase LrgA
DYD83_RS08870	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DYD83_RS08875	COG0156	8-amino-7-oxononanoate synthase activity
DYD83_RS08880	COG2226	methyltransferase
DYD83_RS08890	COG0556	nucleotide-excision repair
DYD83_RS08900	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DYD83_RS08905	COG1271	oxidase subunit
DYD83_RS08910	COG1294	oxidase, subunit
DYD83_RS08920	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DYD83_RS08925	COG0521	Mo-molybdopterin cofactor biosynthetic process
DYD83_RS08935	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DYD83_RS08940	COG0314	molybdopterin synthase activity
DYD83_RS08960	COG0670	Belongs to the BI1 family
DYD83_RS08965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DYD83_RS08970	COG3568	Endonuclease Exonuclease Phosphatase
DYD83_RS08975	COG0842	Transport permease protein
DYD83_RS08980	COG0842	Transport permease protein
DYD83_RS08985	COG1131	(ABC) transporter
DYD83_RS08990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DYD83_RS08995	COG0513	Belongs to the DEAD box helicase family
DYD83_RS09000	COG0697	spore germination
DYD83_RS09015	COG0444	Belongs to the ABC transporter superfamily
DYD83_RS09020	COG4608	Belongs to the ABC transporter superfamily
DYD83_RS09030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DYD83_RS09035	COG0584	glycerophosphoryl diester phosphodiesterase
DYD83_RS09050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DYD83_RS09060	COG2195	Cleaves the N-terminal amino acid of tripeptides
DYD83_RS09065	COG0747	negative chemotaxis
DYD83_RS09070	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DYD83_RS09080	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DYD83_RS09085	COG1686	Belongs to the peptidase S11 family
DYD83_RS09095	COG1349	DNA-binding transcription factor activity
DYD83_RS09105	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DYD83_RS09105	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DYD83_RS09105	COG1013	pyruvate-flavodoxin oxidoreductase activity
DYD83_RS09105	COG0674	pyruvate-flavodoxin oxidoreductase activity
DYD83_RS09110	COG0493	'glutamate synthase
DYD83_RS09115	COG1472	Belongs to the glycosyl hydrolase 3 family
DYD83_RS09130	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DYD83_RS09145	COG0671	phosphoesterase, PA-phosphatase related
DYD83_RS09175	COG1126	abc transporter atp-binding protein
DYD83_RS09180	COG0765	amino acid transport
DYD83_RS09185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYD83_RS09190	COG0783	Belongs to the Dps family
DYD83_RS09200	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DYD83_RS09205	COG1846	Transcriptional regulator
DYD83_RS09210	COG2807	transmembrane transport
DYD83_RS09230	COG0439	Biotin carboxylase
DYD83_RS09240	COG1984	allophanate hydrolase subunit 2
DYD83_RS09250	COG0071	Belongs to the small heat shock protein (HSP20) family
DYD83_RS09270	COG1136	(ABC) transporter
DYD83_RS09275	COG1136	(ABC) transporter
DYD83_RS09275	COG0577	efflux transmembrane transporter activity
DYD83_RS09295	COG4677	pectinesterase activity
DYD83_RS09300	COG3136	membrane protein required for alginate biosynthesis
DYD83_RS09315	COG0601	transmembrane transport
DYD83_RS09320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DYD83_RS09325	COG0444	Belongs to the ABC transporter superfamily
DYD83_RS09330	COG4608	Belongs to the ABC transporter superfamily
DYD83_RS09350	COG2203	Gaf domain
DYD83_RS09350	COG2199	diguanylate cyclase activity
DYD83_RS09360	COG1393	Belongs to the ArsC family
DYD83_RS09385	COG0582	viral genome integration into host DNA
DYD83_RS09400	COG3082	Protein of unknown function (DUF1414)
DYD83_RS09405	COG3081	Nucleoid-associated protein
DYD83_RS09410	COG3275	phosphorelay sensor kinase activity
DYD83_RS09415	COG3279	Response regulator of the LytR AlgR family
DYD83_RS09420	COG2223	nitrite transmembrane transporter activity
DYD83_RS09425	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DYD83_RS09430	COG1061	Type III restriction enzyme res subunit
DYD83_RS09445	COG2814	Major facilitator Superfamily
DYD83_RS09455	COG4172	Belongs to the ABC transporter superfamily
DYD83_RS09460	COG4239	(ABC) transporter, permease
DYD83_RS09465	COG4174	ABC transporter (Permease)
DYD83_RS09470	COG4166	transmembrane transport
DYD83_RS09475	COG0791	NLP P60 protein
DYD83_RS09480	COG0671	phosphoesterase, PA-phosphatase related
DYD83_RS09485	COG0523	cobalamin synthesis protein
DYD83_RS09490	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DYD83_RS09505	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DYD83_RS09505	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DYD83_RS09510	COG1105	Belongs to the carbohydrate kinase PfkB family
DYD83_RS09515	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
DYD83_RS09515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DYD83_RS09515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DYD83_RS09525	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DYD83_RS09530	COG2855	membrane
DYD83_RS09535	COG0583	DNA-binding transcription factor activity
DYD83_RS09540	COG0833	amino acid
DYD83_RS09550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DYD83_RS09565	COG0508	dehydrogenase complex catalyzes the overall conversion of
DYD83_RS09575	COG1172	Belongs to the binding-protein-dependent transport system permease family
DYD83_RS09580	COG1129	ABC transporter
DYD83_RS09585	COG0371	Dehydrogenase
DYD83_RS09605	COG0583	DNA-binding transcription factor activity
DYD83_RS09610	COG0840	transmembrane signaling receptor activity
DYD83_RS09620	COG0840	transmembrane signaling receptor activity
DYD83_RS09625	COG0840	transmembrane signaling receptor activity
DYD83_RS09630	COG0840	transmembrane signaling receptor activity
DYD83_RS09635	COG0302	gtp cyclohydrolase
DYD83_RS09645	COG2311	Membrane
DYD83_RS09650	COG2949	membrane
DYD83_RS09655	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DYD83_RS09660	COG2133	pyrroloquinoline quinone binding
DYD83_RS09665	COG0625	glutathione transferase activity
DYD83_RS09670	COG1464	Belongs to the NlpA lipoprotein family
DYD83_RS09675	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DYD83_RS09680	COG2011	ABC-type metal ion transport system permease component
DYD83_RS09685	COG2267	carboxylic ester hydrolase activity
DYD83_RS09690	COG1686	Belongs to the peptidase S11 family
DYD83_RS09695	COG1349	DNA-binding transcription factor activity
DYD83_RS09700	COG0569	domain protein
DYD83_RS09700	COG2985	domain, Protein
DYD83_RS09720	COG0189	ligase activity
DYD83_RS09730	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DYD83_RS09735	COG3842	ATPase activity
DYD83_RS09740	COG1176	ABC-type spermidine putrescine transport system, permease component I
DYD83_RS09745	COG1177	transmembrane transport
DYD83_RS09755	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DYD83_RS09765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYD83_RS09770	COG4160	amino acid transport
DYD83_RS09775	COG4215	(ABC) transporter
DYD83_RS09780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYD83_RS09785	COG1126	abc transporter atp-binding protein
DYD83_RS09790	COG0393	Putative heavy-metal-binding
DYD83_RS09795	COG3023	N-Acetylmuramoyl-L-alanine amidase
DYD83_RS09800	COG0702	epimerase
DYD83_RS09805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DYD83_RS09810	COG1151	hydroxylamine reductase activity
DYD83_RS09815	COG3593	DNA synthesis involved in DNA repair
DYD83_RS09820	COG1278	Cold shock
DYD83_RS09825	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DYD83_RS09830	COG0542	response to heat
DYD83_RS09835	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DYD83_RS09840	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DYD83_RS09845	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DYD83_RS09850	COG4988	ABC transporter
DYD83_RS09855	COG0492	ferredoxin-NADP+ reductase activity
DYD83_RS09865	COG3107	peptidoglycan biosynthetic process
DYD83_RS09865	COG1674	ftsk spoiiie
DYD83_RS09870	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DYD83_RS09875	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DYD83_RS09880	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DYD83_RS09905	COG0583	DNA-binding transcription factor activity
DYD83_RS09910	COG2814	Major facilitator Superfamily
DYD83_RS09920	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DYD83_RS09925	COG1882	Formate acetyltransferase
DYD83_RS09930	COG2116	formate transmembrane transporter activity
DYD83_RS09935	COG1944	ATP diphosphatase activity
DYD83_RS09940	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DYD83_RS09945	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DYD83_RS09950	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DYD83_RS09955	COG0539	negative regulation of cytoplasmic translation
DYD83_RS09960	COG0776	regulation of translation
DYD83_RS09975	COG0140	phosphoribosyl-ATP diphosphatase activity
DYD83_RS09975	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DYD83_RS09980	COG0107	imidazoleglycerol-phosphate synthase activity
DYD83_RS09985	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DYD83_RS09990	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DYD83_RS09995	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DYD83_RS09995	COG0131	Imidazoleglycerol-phosphate dehydratase
DYD83_RS10000	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DYD83_RS10005	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DYD83_RS10010	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DYD83_RS10020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DYD83_RS10025	COG0840	transmembrane signaling receptor activity
DYD83_RS10040	COG3493	citrate carrier protein
DYD83_RS10045	COG0179	Fumarylacetoacetate (FAA) hydrolase
DYD83_RS10050	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
DYD83_RS10055	COG3052	prosthetic group binding
DYD83_RS10070	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
DYD83_RS10070	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
DYD83_RS10075	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
DYD83_RS10080	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
DYD83_RS10090	COG0531	amino acid
DYD83_RS10100	COG2925	Exonuclease
DYD83_RS10105	COG2926	Belongs to the UPF0265 family
DYD83_RS10115	COG2333	competence protein COMEC
DYD83_RS10115	COG0658	competence protein
DYD83_RS10120	COG1132	(ABC) transporter
DYD83_RS10125	COG1663	tetraacyldisaccharide 4'-kinase activity
DYD83_RS10130	COG2835	tetraacyldisaccharide 4'-kinase activity
DYD83_RS10135	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DYD83_RS10145	COG3173	Aminoglycoside phosphotransferase
DYD83_RS10150	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DYD83_RS10155	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DYD83_RS10160	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
DYD83_RS10165	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
DYD83_RS10170	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
DYD83_RS10195	COG2132	Multicopper oxidase
DYD83_RS10200	COG1733	regulation of RNA biosynthetic process
DYD83_RS10210	COG0494	nUDIX hydrolase
DYD83_RS10220	COG0625	glutathione transferase activity
DYD83_RS10230	COG1349	DNA-binding transcription factor activity
DYD83_RS10260	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DYD83_RS10265	COG3381	protein complex oligomerization
DYD83_RS10275	COG2999	glutathione oxidoreductase activity
DYD83_RS10280	COG0477	Major facilitator Superfamily
DYD83_RS10285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DYD83_RS10290	COG3132	Protein of unknown function, DUF480
DYD83_RS10395	COG0018	arginyl-trna synthetase
DYD83_RS10400	COG3102	Protein conserved in bacteria
DYD83_RS10405	COG3142	Participates in the control of copper homeostasis
DYD83_RS10415	COG0500	methyltransferase
DYD83_RS10420	COG2226	methyltransferase
DYD83_RS10425	COG3788	relative of glutathione S-transferase, MAPEG superfamily
DYD83_RS10430	COG1801	Protein of unknown function DUF72
DYD83_RS10435	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DYD83_RS10440	COG0494	nUDIX hydrolase
DYD83_RS10445	COG0217	transcriptional regulatory protein
DYD83_RS10455	COG2390	Transcriptional regulator
DYD83_RS10470	COG3395	kinase activity
DYD83_RS10485	COG0698	ribose 5-phosphate isomerase
DYD83_RS10490	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DYD83_RS10495	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DYD83_RS10500	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DYD83_RS10505	COG0632	four-way junction helicase activity
DYD83_RS10510	COG2255	four-way junction helicase activity
DYD83_RS10515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DYD83_RS10520	COG1121	(ABC) transporter
DYD83_RS10525	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
DYD83_RS10530	COG0739	heme binding
DYD83_RS10535	COG1560	Kdo2-lipid A biosynthetic process
DYD83_RS10550	COG0469	pyruvate kinase activity
DYD83_RS10555	COG1737	Transcriptional regulator
DYD83_RS10560	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DYD83_RS10565	COG0800	Aldolase
DYD83_RS10570	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DYD83_RS10575	COG1770	oligopeptidase
DYD83_RS10590	COG1276	copper resistance
DYD83_RS10595	COG1528	Iron-storage protein
DYD83_RS10605	COG2204	response regulator
DYD83_RS10645	COG2261	transglycosylase associated protein
DYD83_RS10665	COG0444	Belongs to the ABC transporter superfamily
DYD83_RS10670	COG2718	Belongs to the UPF0229 family
DYD83_RS10675	COG2766	serine protein kinase
DYD83_RS10680	COG3713	MltA-interacting MipA family protein
DYD83_RS10685	COG0656	L-ascorbic acid biosynthetic process
DYD83_RS10700	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DYD83_RS10705	COG3139	Protein of unknown function (DUF1315)
DYD83_RS10710	COG1335	isochorismatase
DYD83_RS10715	COG0252	asparaginase activity
DYD83_RS10720	COG0616	signal peptide processing
DYD83_RS10725	COG0778	Nitroreductase
DYD83_RS10745	COG2860	membrane
DYD83_RS10755	COG0788	formyltetrahydrofolate deformylase activity
DYD83_RS10760	COG3012	SEC-C Motif Domain Protein
DYD83_RS10765	COG1752	Esterase of the alpha-beta hydrolase superfamily
DYD83_RS10770	COG0745	RESPONSE REGULATOR receiver
DYD83_RS10775	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DYD83_RS10785	COG1435	thymidine kinase activity
DYD83_RS10790	COG1454	alcohol dehydrogenase
DYD83_RS10790	COG1012	belongs to the aldehyde dehydrogenase family
DYD83_RS10795	COG2095	MarC family integral membrane protein
DYD83_RS10815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DYD83_RS10820	COG0444	Belongs to the ABC transporter superfamily
DYD83_RS10835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DYD83_RS10845	COG0840	transmembrane signaling receptor activity
DYD83_RS10850	COG2350	Protein conserved in bacteria
DYD83_RS10865	COG2917	probably involved in intracellular septation
DYD83_RS10875	COG0727	PFAM Uncharacterised protein family (UPF0153)
DYD83_RS10880	COG3047	cAMP biosynthetic process
DYD83_RS10885	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DYD83_RS10890	COG0159	tryptophan synthase activity
DYD83_RS10895	COG0133	tryptophan synthase activity
DYD83_RS10905	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DYD83_RS10910	COG0512	Glutamine amidotransferase of anthranilate synthase
DYD83_RS10920	COG0613	PHP domain protein
DYD83_RS10925	COG0009	L-threonylcarbamoyladenylate synthase
DYD83_RS10930	COG1187	pseudouridine synthase activity
DYD83_RS10935	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
DYD83_RS10940	COG1028	Short-chain dehydrogenase reductase Sdr
DYD83_RS10945	COG0616	signal peptide processing
DYD83_RS10965	COG0583	DNA-binding transcription factor activity
DYD83_RS10970	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DYD83_RS10980	COG4659	FMN binding
DYD83_RS10985	COG4658	electron transport chain
DYD83_RS10990	COG4656	Part of a membrane complex involved in electron transport
DYD83_RS10995	COG2878	Part of a membrane complex involved in electron transport
DYD83_RS11000	COG4657	Part of a membrane complex involved in electron transport
DYD83_RS11010	COG2160	L-arabinose isomerase activity
DYD83_RS11015	COG1069	ribulokinase activity
DYD83_RS11020	COG1879	ABC-type sugar transport system periplasmic component
DYD83_RS11025	COG1129	ABC transporter
DYD83_RS11030	COG1172	Belongs to the binding-protein-dependent transport system permease family
DYD83_RS11040	COG0673	inositol 2-dehydrogenase activity
DYD83_RS11045	COG0385	Bile acid
DYD83_RS11055	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DYD83_RS11060	COG5339	Protein conserved in bacteria
DYD83_RS11065	COG1482	cell wall glycoprotein biosynthetic process
DYD83_RS11070	COG0114	fumarate hydratase activity
DYD83_RS11080	COG2814	Major facilitator Superfamily
DYD83_RS11085	COG0583	DNA-binding transcription factor activity
DYD83_RS11090	COG1940	carbohydrate kinase activity
DYD83_RS11095	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DYD83_RS11110	COG4221	oxidoreductase activity
DYD83_RS11115	COG2226	methyltransferase
DYD83_RS11120	COG1215	transferase activity, transferring glycosyl groups
DYD83_RS11145	COG4305	rare lipoprotein A
DYD83_RS11160	COG2995	paraquat-inducible protein a
DYD83_RS11165	COG3008	intermembrane lipid transfer
DYD83_RS11190	COG3158	transport of potassium into the cell
DYD83_RS11235	COG0702	epimerase
DYD83_RS11265	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
DYD83_RS11270	COG0483	inositol monophosphate 1-phosphatase activity
DYD83_RS11275	COG0584	glycerophosphoryl diester phosphodiesterase
DYD83_RS11295	COG3842	ATPase activity
DYD83_RS11310	COG3479	Phenolic acid decarboxylase
DYD83_RS11320	COG0840	transmembrane signaling receptor activity
DYD83_RS11335	COG0840	transmembrane signaling receptor activity
DYD83_RS11345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DYD83_RS11355	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DYD83_RS11360	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DYD83_RS11370	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DYD83_RS11380	COG2890	protein-(glutamine-N5) methyltransferase activity
DYD83_RS11385	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DYD83_RS11390	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DYD83_RS11395	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DYD83_RS11400	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DYD83_RS11405	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DYD83_RS11415	COG0583	DNA-binding transcription factor activity
DYD83_RS11425	COG0193	aminoacyl-tRNA hydrolase activity
DYD83_RS11430	COG0012	GTP binding
DYD83_RS11435	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
DYD83_RS11435	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
DYD83_RS11445	COG0513	Belongs to the DEAD box helicase family
DYD83_RS11470	COG3706	GGDEF domain
DYD83_RS11475	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DYD83_RS11480	COG1074	ATP-dependent DNA helicase activity
DYD83_RS11485	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DYD83_RS11595	COG3210	domain, Protein
DYD83_RS11600	COG3210	domain, Protein
DYD83_RS11605	COG3210	domain, Protein
DYD83_RS11610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DYD83_RS11615	COG2719	SpoVR family
DYD83_RS11620	COG2186	Transcriptional regulator
DYD83_RS11625	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DYD83_RS11630	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DYD83_RS11635	COG2983	Belongs to the UPF0260 family
DYD83_RS11640	COG0179	Fumarylacetoacetate (FAA) hydrolase
DYD83_RS11650	COG0850	regulation of cytokinetic process
DYD83_RS11655	COG2894	cell division
DYD83_RS11660	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DYD83_RS11665	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
DYD83_RS11670	COG0318	PFAM AMP-dependent synthetase and ligase
DYD83_RS11675	COG3065	identical protein binding
DYD83_RS11685	COG1199	ATP-dependent helicase activity
DYD83_RS11690	COG0251	oxidation-reduction process
DYD83_RS11705	COG0494	nUDIX hydrolase
DYD83_RS11710	COG1760	l-serine dehydratase
DYD83_RS11715	COG0840	transmembrane signaling receptor activity
DYD83_RS11720	COG1253	flavin adenine dinucleotide binding
DYD83_RS11725	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DYD83_RS11725	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DYD83_RS11730	COG3715	PTS system
DYD83_RS11735	COG3716	PTS system mannose fructose sorbose family IID component
DYD83_RS11745	COG1971	Probably functions as a manganese efflux pump
DYD83_RS11750	COG2226	methyltransferase
DYD83_RS11765	COG3001	Fructosamine kinase
DYD83_RS11775	COG1917	Cupin 2, conserved barrel domain protein
DYD83_RS11780	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
DYD83_RS11785	COG1028	Short-chain dehydrogenase reductase Sdr
DYD83_RS11795	COG1175	transmembrane transport
DYD83_RS11800	COG0395	ABC-type sugar transport system, permease component
DYD83_RS11805	COG3842	ATPase activity
DYD83_RS11815	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DYD83_RS11820	COG2755	lipolytic protein G-D-S-L family
DYD83_RS11820	COG0657	acetylesterase activity
DYD83_RS11825	COG1988	membrane-bound metal-dependent
DYD83_RS11830	COG1823	symporter activity
DYD83_RS11835	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DYD83_RS11840	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DYD83_RS11855	COG0776	regulation of translation
DYD83_RS11860	COG0072	phenylalanine-tRNA ligase activity
DYD83_RS11860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DYD83_RS11865	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DYD83_RS11880	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DYD83_RS11885	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DYD83_RS11890	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DYD83_RS11905	COG0823	Involved in the tonB-independent uptake of proteins
DYD83_RS11910	COG0501	Belongs to the peptidase M48B family
DYD83_RS11920	COG0538	isocitrate dehydrogenase activity
DYD83_RS11925	COG1187	pseudouridine synthase activity
DYD83_RS11935	COG0482	sulfurtransferase activity
DYD83_RS11940	COG2915	High frequency lysogenization protein hflD homolog
DYD83_RS11945	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DYD83_RS11960	COG2850	peptidyl-arginine hydroxylation
DYD83_RS11965	COG2195	Cleaves the N-terminal amino acid of tripeptides
DYD83_RS11995	COG3547	Transposase (IS116 IS110 IS902 family)
DYD83_RS12020	COG3210	domain, Protein
DYD83_RS12035	COG2831	hemolysin activation secretion protein
DYD83_RS12085	COG2951	lytic endotransglycosylase activity
DYD83_RS12120	COG2197	response regulator
DYD83_RS12125	COG4585	Histidine kinase
DYD83_RS12175	COG4794	Type iii secretion
DYD83_RS12185	COG4792	protein secretion
DYD83_RS12195	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
DYD83_RS12200	COG0840	transmembrane signaling receptor activity
DYD83_RS12205	COG0840	transmembrane signaling receptor activity
DYD83_RS12225	COG0626	cystathionine gamma-synthase activity
DYD83_RS12230	COG0765	amino acid transport
DYD83_RS12235	COG0765	amino acid transport
DYD83_RS12240	COG1126	abc transporter atp-binding protein
DYD83_RS12250	COG0561	phosphatase activity
DYD83_RS12255	COG2223	nitrite transmembrane transporter activity
DYD83_RS12260	COG0483	inositol monophosphate 1-phosphatase activity
DYD83_RS12265	COG1349	DNA-binding transcription factor activity
DYD83_RS12270	COG4774	siderophore transport
DYD83_RS12285	COG1176	ABC-type spermidine putrescine transport system, permease component I
DYD83_RS12295	COG1012	belongs to the aldehyde dehydrogenase family
DYD83_RS12300	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DYD83_RS12310	COG3842	ATPase activity
DYD83_RS12340	COG0667	Aldo Keto reductase
DYD83_RS12360	COG0583	DNA-binding transcription factor activity
DYD83_RS12380	COG0656	L-ascorbic acid biosynthetic process
DYD83_RS12400	COG1454	alcohol dehydrogenase
DYD83_RS12410	COG2181	nitrate reductase activity
DYD83_RS12415	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DYD83_RS12420	COG1140	nitrate reductase beta subunit
DYD83_RS12425	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DYD83_RS12430	COG2223	nitrite transmembrane transporter activity
DYD83_RS12435	COG3850	Histidine kinase
DYD83_RS12440	COG2197	response regulator
DYD83_RS12455	COG0300	oxidoreductase activity
DYD83_RS12470	COG1408	metallophosphoesterase
DYD83_RS12475	COG0583	DNA-binding transcription factor activity
DYD83_RS12485	COG0793	Belongs to the peptidase S41A family
DYD83_RS12490	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
DYD83_RS12495	COG1956	GAF domain-containing protein
DYD83_RS12500	COG2995	paraquat-inducible protein a
DYD83_RS12505	COG3008	intermembrane lipid transfer
DYD83_RS12510	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
DYD83_RS12510	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DYD83_RS12520	COG0840	transmembrane signaling receptor activity
DYD83_RS12545	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DYD83_RS12570	COG2175	clavaminate synthase activity
DYD83_RS12600	COG2840	Smr protein MutS2
DYD83_RS12620	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DYD83_RS12675	COG0402	S-adenosylhomocysteine deaminase activity
DYD83_RS12685	COG0840	transmembrane signaling receptor activity
DYD83_RS12695	COG0840	transmembrane signaling receptor activity
DYD83_RS12705	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DYD83_RS12710	COG0038	chloride channel
DYD83_RS12720	COG4608	Belongs to the ABC transporter superfamily
DYD83_RS12725	COG0444	Belongs to the ABC transporter superfamily
DYD83_RS12730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DYD83_RS12735	COG0601	transmembrane transport
DYD83_RS12740	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
DYD83_RS12745	COG0387	Pfam Sodium calcium exchanger
DYD83_RS12750	COG0659	secondary active sulfate transmembrane transporter activity
DYD83_RS12760	COG0745	RESPONSE REGULATOR receiver
DYD83_RS12765	COG2205	protein histidine kinase activity
DYD83_RS12775	COG3591	Belongs to the peptidase S1B family
DYD83_RS12780	COG1643	Atp-dependent helicase
DYD83_RS12785	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DYD83_RS12795	COG2911	Protein conserved in bacteria
DYD83_RS12800	COG0840	transmembrane signaling receptor activity
DYD83_RS12805	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DYD83_RS12815	COG0840	transmembrane signaling receptor activity
DYD83_RS12845	COG0037	tRNA processing
DYD83_RS12850	COG0598	Magnesium transport protein CorA
DYD83_RS12855	COG4166	transmembrane transport
DYD83_RS12860	COG2866	Carboxypeptidase
DYD83_RS12865	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DYD83_RS12870	COG0477	Major facilitator Superfamily
DYD83_RS12885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DYD83_RS12900	COG2271	Major facilitator Superfamily
DYD83_RS12905	COG3768	UPF0283 membrane protein
DYD83_RS12910	COG3106	COG3106 Predicted ATPase
DYD83_RS12915	COG1983	PspC domain protein
DYD83_RS12925	COG1842	Phage shock protein A
DYD83_RS12930	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DYD83_RS12950	COG4166	transmembrane transport
DYD83_RS12965	COG4172	Belongs to the ABC transporter superfamily
DYD83_RS12980	COG0583	DNA-binding transcription factor activity
DYD83_RS12985	COG0243	molybdopterin cofactor binding
DYD83_RS13000	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
DYD83_RS13005	COG4989	oxidoreductase activity
DYD83_RS13010	COG1966	Carbon starvation protein
DYD83_RS13030	COG0023	Translation Initiation Factor
DYD83_RS13040	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DYD83_RS13045	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
DYD83_RS13050	COG0671	phosphoesterase, PA-phosphatase related
DYD83_RS13070	COG0625	glutathione transferase activity
DYD83_RS13075	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
DYD83_RS13085	COG0259	pyridoxamine-phosphate oxidase activity
DYD83_RS13090	COG3895	Periplasmic Protein
DYD83_RS13095	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DYD83_RS13110	COG3313	Fe-S protein
DYD83_RS13115	COG0346	lactoylglutathione lyase activity
DYD83_RS13120	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DYD83_RS13125	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DYD83_RS13130	COG0791	NLP P60 protein
DYD83_RS13140	COG1609	Transcriptional regulator
DYD83_RS13145	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DYD83_RS13150	COG0307	riboflavin synthase, alpha
DYD83_RS13155	COG0534	Mate efflux family protein
DYD83_RS13200	COG0534	Mate efflux family protein
DYD83_RS13215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DYD83_RS13230	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DYD83_RS13240	COG0156	8-amino-7-oxononanoate synthase activity
DYD83_RS13250	COG3321	synthase
DYD83_RS13250	COG4221	oxidoreductase activity
DYD83_RS13250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DYD83_RS13250	COG1028	Short-chain dehydrogenase reductase Sdr
DYD83_RS13265	COG1403	HNH endonuclease
DYD83_RS13270	COG2382	esterase
DYD83_RS13315	COG1902	pentaerythritol trinitrate reductase activity
DYD83_RS13320	COG0583	DNA-binding transcription factor activity
DYD83_RS13330	COG4238	major outer membrane lipoprotein
DYD83_RS13335	COG1388	LysM domain
DYD83_RS13335	COG1376	ErfK ybiS ycfS ynhG family protein
DYD83_RS13340	COG2166	iron-sulfur cluster assembly
DYD83_RS13345	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DYD83_RS13350	COG0719	Fe-S assembly protein
DYD83_RS13355	COG0396	ATPase activity
DYD83_RS13360	COG0719	Fe-S assembly protein
DYD83_RS13365	COG0316	Belongs to the HesB IscA family
DYD83_RS13375	COG2050	protein possibly involved in aromatic compounds catabolism
DYD83_RS13380	COG0247	lactate metabolic process
DYD83_RS13380	COG0277	FAD linked oxidase domain protein
DYD83_RS13385	COG0628	permease
DYD83_RS13395	COG0574	Belongs to the PEP-utilizing enzyme family
DYD83_RS13395	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DYD83_RS13400	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DYD83_RS13405	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DYD83_RS13410	COG3130	regulation of translation
DYD83_RS13415	COG3009	Protein conserved in bacteria
DYD83_RS13420	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DYD83_RS13420	COG3008	intermembrane lipid transfer
DYD83_RS13425	COG2995	paraquat-inducible protein a
DYD83_RS13430	COG0488	(ABC) transporter
DYD83_RS13435	COG0116	Belongs to the methyltransferase superfamily
DYD83_RS13435	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DYD83_RS13440	COG0633	Ferredoxin
DYD83_RS13440	COG3217	Mosc domain protein beta barrel domain protein
DYD83_RS13450	COG0167	dihydroorotate dehydrogenase activity
DYD83_RS13455	COG0431	NADPH-dependent FMN reductase
DYD83_RS13460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DYD83_RS13465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DYD83_RS13470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DYD83_RS13475	COG1116	anion transmembrane transporter activity
DYD83_RS13480	COG0308	aminopeptidase N
DYD83_RS13485	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DYD83_RS13490	COG0017	Asparaginyl-tRNA synthetase
DYD83_RS13505	COG1448	Aminotransferase
DYD83_RS13510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DYD83_RS13515	COG3108	Peptidase M15
DYD83_RS13520	COG2989	Protein conserved in bacteria
DYD83_RS13525	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DYD83_RS13535	COG0095	Lipoate-protein ligase
DYD83_RS13540	COG0791	NLP P60 protein
DYD83_RS13545	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
DYD83_RS13550	COG0386	Belongs to the glutathione peroxidase family
DYD83_RS13555	COG4139	cobalamin transport
DYD83_RS13575	COG4591	ABC-type transport system involved in lipoprotein release permease component
DYD83_RS13580	COG1136	(ABC) transporter
DYD83_RS13585	COG4591	ABC-type transport system involved in lipoprotein release permease component
DYD83_RS13590	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DYD83_RS13595	COG2200	EAL domain
DYD83_RS13600	COG0443	Heat shock 70 kDa protein
DYD83_RS13615	COG2271	Major facilitator Superfamily
DYD83_RS13620	COG1609	Transcriptional regulator
DYD83_RS13625	COG3134	Outer membrane lipoprotein
DYD83_RS13630	COG1252	NADH dehydrogenase
DYD83_RS13640	COG1472	Belongs to the glycosyl hydrolase 3 family
DYD83_RS13650	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
DYD83_RS13655	COG5633	Lipoprotein
DYD83_RS13660	COG0537	adenosine 5'-monophosphoramidase activity
DYD83_RS13665	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DYD83_RS13670	COG1263	PTS System
DYD83_RS13670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DYD83_RS13675	COG0084	hydrolase, TatD family'
DYD83_RS13680	COG0470	DNA polymerase III
DYD83_RS13685	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DYD83_RS13690	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DYD83_RS13695	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DYD83_RS13700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DYD83_RS13705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DYD83_RS13710	COG1028	Short-chain dehydrogenase reductase Sdr
DYD83_RS13720	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DYD83_RS13725	COG0416	fatty acid biosynthetic process
DYD83_RS13730	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DYD83_RS13735	COG1399	metal-binding, possibly nucleic acid-binding protein
DYD83_RS13740	COG0424	maF-like protein
DYD83_RS13745	COG0564	pseudouridine synthase activity
DYD83_RS13750	COG1530	ribonuclease E activity
DYD83_RS13760	COG0418	dihydroorotase activity
DYD83_RS13775	COG3038	cytochrome b561
DYD83_RS13780	COG2353	YceI-like domain
DYD83_RS13785	COG1054	Belongs to the UPF0176 family
DYD83_RS13795	COG1560	Kdo2-lipid A biosynthetic process
DYD83_RS13800	COG2814	Major facilitator Superfamily
DYD83_RS13805	COG2943	transferase activity, transferring hexosyl groups
DYD83_RS13810	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
DYD83_RS13825	COG0840	transmembrane signaling receptor activity
DYD83_RS13845	COG1067	ATP-dependent peptidase activity
DYD83_RS13850	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DYD83_RS13860	COG1012	belongs to the aldehyde dehydrogenase family
DYD83_RS13885	COG1702	phosphate starvation-inducible protein PhoH
DYD83_RS13895	COG1191	sigma factor activity
DYD83_RS13910	COG0673	inositol 2-dehydrogenase activity
DYD83_RS13925	COG0500	methyltransferase
DYD83_RS13935	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DYD83_RS13950	COG1677	Flagellar hook-basal body complex protein FliE
DYD83_RS13965	COG1317	bacterial-type flagellum organization
DYD83_RS13970	COG1157	protein secretion by the type III secretion system
DYD83_RS13980	COG3144	bacterial-type flagellum assembly
DYD83_RS13985	COG1580	Controls the rotational direction of flagella during chemotaxis
DYD83_RS13995	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DYD83_RS14020	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DYD83_RS14025	COG1256	bacterial-type flagellum assembly
DYD83_RS14035	COG1706	bacterial-type flagellum-dependent cell motility
DYD83_RS14040	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DYD83_RS14050	COG4787	bacterial-type flagellum-dependent cell motility
DYD83_RS14060	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DYD83_RS14065	COG1558	bacterial-type flagellum-dependent cell motility
DYD83_RS14070	COG1815	bacterial-type flagellum-dependent cell motility
DYD83_RS14080	COG2747	anti-sigma28 factor FlgM
DYD83_RS14100	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DYD83_RS14105	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
DYD83_RS14110	COG0745	RESPONSE REGULATOR receiver
DYD83_RS14115	COG2201	protein-glutamate methylesterase activity
DYD83_RS14120	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DYD83_RS14125	COG0840	transmembrane signaling receptor activity
DYD83_RS14130	COG0835	chemotaxis
DYD83_RS14135	COG2198	Histidine kinase
DYD83_RS14135	COG0643	Histidine kinase
DYD83_RS14140	COG1360	Flagellar Motor Protein
DYD83_RS14160	COG1979	alcohol dehydrogenase
DYD83_RS14165	COG0840	transmembrane signaling receptor activity
DYD83_RS14185	COG0534	Mate efflux family protein
DYD83_RS14195	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DYD83_RS14200	COG4733	cellulase activity
DYD83_RS14240	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DYD83_RS14245	COG0322	excinuclease ABC activity
DYD83_RS14250	COG2197	response regulator
DYD83_RS14265	COG1113	amino acid transport
DYD83_RS14280	COG1819	glycosyl
DYD83_RS14285	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DYD83_RS14295	COG0840	transmembrane signaling receptor activity
DYD83_RS14300	COG1619	proteins homologs of microcin C7 resistance protein MccF
DYD83_RS14305	COG0583	DNA-binding transcription factor activity
DYD83_RS14310	COG0436	Aminotransferase
DYD83_RS14340	COG1648	precorrin-2 dehydrogenase activity
DYD83_RS14340	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DYD83_RS14345	COG0243	molybdopterin cofactor binding
DYD83_RS14350	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DYD83_RS14350	COG2146	nitrite reductase [NAD(P)H] activity
DYD83_RS14355	COG1116	anion transmembrane transporter activity
DYD83_RS14365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DYD83_RS14370	COG3707	response regulator
DYD83_RS14385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DYD83_RS14390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DYD83_RS14400	COG2814	Major facilitator Superfamily
DYD83_RS14405	COG0657	acetylesterase activity
DYD83_RS14410	COG3058	Necessary for formate dehydrogenase activity
DYD83_RS14415	COG2271	Major facilitator Superfamily
DYD83_RS14420	COG2864	formate dehydrogenase
DYD83_RS14425	COG0437	4 iron, 4 sulfur cluster binding
DYD83_RS14430	COG0243	molybdopterin cofactor binding
DYD83_RS14430	COG3383	formate dehydrogenase (NAD+) activity
DYD83_RS14435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DYD83_RS14440	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DYD83_RS14440	COG0519	Catalyzes the synthesis of GMP from XMP
DYD83_RS14450	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
DYD83_RS14455	COG0309	Hydrogenase expression formation protein (HypE)
DYD83_RS14460	COG0409	Hydrogenase expression formation protein
DYD83_RS14465	COG0298	carbon dioxide binding
DYD83_RS14470	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DYD83_RS14480	COG1773	rubredoxin
DYD83_RS14485	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
DYD83_RS14490	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
DYD83_RS14495	COG5557	Pfam Polysulphide reductase, NrfD
DYD83_RS14500	COG0437	4 iron, 4 sulfur cluster binding
DYD83_RS14505	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
DYD83_RS14510	COG0488	(ABC) transporter
DYD83_RS14515	COG0384	phenazine biosynthesis protein PhzF
DYD83_RS14520	COG2132	Multicopper oxidase
DYD83_RS14525	COG1007	ATP synthesis coupled electron transport
DYD83_RS14530	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DYD83_RS14535	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DYD83_RS14540	COG0713	ATP synthesis coupled electron transport
DYD83_RS14545	COG0839	Belongs to the complex I subunit 6 family
DYD83_RS14550	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DYD83_RS14555	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DYD83_RS14565	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DYD83_RS14575	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DYD83_RS14575	COG0649	NAD binding
DYD83_RS14585	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DYD83_RS14590	COG0583	DNA-binding transcription factor activity
DYD83_RS14595	COG0436	Aminotransferase
DYD83_RS14600	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
DYD83_RS14605	COG0490	domain, Protein
DYD83_RS14605	COG0471	metal ion transport
DYD83_RS14610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DYD83_RS14615	COG3013	Belongs to the UPF0304 family
DYD83_RS14620	COG3092	negative regulation of chromosome organization
DYD83_RS14625	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DYD83_RS14630	COG0280	phosphate acetyltransferase
DYD83_RS14630	COG0857	belongs to the CobB CobQ family
DYD83_RS14635	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DYD83_RS14640	COG0622	Phosphoesterase
DYD83_RS14645	COG0625	glutathione transferase activity
DYD83_RS14650	COG1090	epimerase
DYD83_RS14665	COG4215	(ABC) transporter
DYD83_RS14670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYD83_RS14675	COG0163	prenyltransferase activity
DYD83_RS14680	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DYD83_RS14685	COG1286	toxin biosynthetic process
DYD83_RS14690	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
DYD83_RS14695	COG0285	dihydrofolate synthase activity
DYD83_RS14700	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DYD83_RS14705	COG0586	Pfam SNARE associated Golgi protein
DYD83_RS14710	COG0101	tRNA pseudouridine synthase activity
DYD83_RS14715	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DYD83_RS14720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DYD83_RS14730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DYD83_RS14735	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
DYD83_RS14735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DYD83_RS14755	COG1764	response to oxidative stress
DYD83_RS14785	COG3101	peptidyl-lysine hydroxylation
DYD83_RS14790	COG0730	response to heat
DYD83_RS14795	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
DYD83_RS14800	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DYD83_RS14805	COG2890	protein-(glutamine-N5) methyltransferase activity
DYD83_RS14810	COG2840	Smr protein MutS2
DYD83_RS14815	COG2062	phosphohistidine phosphatase, SixA
DYD83_RS14820	COG1250	3-hydroxyacyl-CoA dehydrogenase
DYD83_RS14820	COG1024	Enoyl-CoA hydratase
DYD83_RS14825	COG0183	Belongs to the thiolase family
DYD83_RS14830	COG3691	Protein conserved in bacteria
DYD83_RS14840	COG2067	long-chain fatty acid transport protein
DYD83_RS14845	COG0579	oxidoreductase
DYD83_RS14865	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DYD83_RS14880	COG4592	Periplasmic binding protein
DYD83_RS14890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DYD83_RS14895	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DYD83_RS14900	COG1120	ATPase activity
DYD83_RS14915	COG2382	esterase
DYD83_RS14920	COG4774	siderophore transport
DYD83_RS14925	COG1169	isochorismate synthase
DYD83_RS14930	COG1021	2,3-dihydroxybenzoate-AMP ligase
DYD83_RS14935	COG1535	isochorismatase
DYD83_RS14935	COG3433	isochorismatase activity
DYD83_RS14940	COG1028	Short-chain dehydrogenase reductase Sdr
DYD83_RS14945	COG2050	protein possibly involved in aromatic compounds catabolism
DYD83_RS14950	COG1902	pentaerythritol trinitrate reductase activity
DYD83_RS14960	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DYD83_RS15015	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DYD83_RS15020	COG1450	Type ii and iii secretion system protein
DYD83_RS15025	COG3031	protein transport across the cell outer membrane
DYD83_RS15035	COG3266	domain, Protein
DYD83_RS15045	COG0436	Aminotransferase
DYD83_RS15050	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DYD83_RS15055	COG1511	domain protein
DYD83_RS15055	COG3264	Mechanosensitive ion channel
DYD83_RS15065	COG0583	DNA-binding transcription factor activity
DYD83_RS15085	COG2850	peptidyl-arginine hydroxylation
DYD83_RS15110	COG0583	DNA-binding transcription factor activity
DYD83_RS15125	COG1263	PTS System
DYD83_RS15125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DYD83_RS15130	COG1874	Beta-galactosidase
DYD83_RS15140	COG3833	ABC-type maltose transport systems, permease component
DYD83_RS15145	COG1175	transmembrane transport
DYD83_RS15150	COG2182	Extracellular solute-binding protein
DYD83_RS15160	COG1473	amidohydrolase
DYD83_RS15170	COG5297	Belongs to the glycosyl hydrolase family 6
DYD83_RS15185	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DYD83_RS15190	COG2986	histidine ammonia-lyase
DYD83_RS15235	COG3290	protein histidine kinase activity
DYD83_RS15240	COG4565	transcriptional regulatory protein
DYD83_RS15245	COG2986	histidine ammonia-lyase
DYD83_RS15275	COG0402	S-adenosylhomocysteine deaminase activity
DYD83_RS15290	COG0840	transmembrane signaling receptor activity
DYD83_RS15295	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DYD83_RS15300	COG2501	S4 domain
DYD83_RS15305	COG0215	cysteine-tRNA ligase activity
DYD83_RS15315	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DYD83_RS15320	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DYD83_RS15325	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DYD83_RS15330	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DYD83_RS15335	COG0814	amino acid
DYD83_RS15340	COG1760	l-serine dehydratase
DYD83_RS15360	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DYD83_RS15365	COG0581	inorganic phosphate transmembrane transporter activity
DYD83_RS15375	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DYD83_RS15385	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DYD83_RS15390	COG0589	response to stress
DYD83_RS15455	COG3646	Phage regulatory protein
DYD83_RS15560	COG3772	lysozyme
DYD83_RS15630	COG0305	Participates in initiation and elongation during chromosome replication
DYD83_RS15635	COG1484	DNA-dependent DNA replication
DYD83_RS15640	COG1802	Transcriptional regulator
DYD83_RS15640	COG4626	Terminase
DYD83_RS15660	COG1396	sequence-specific DNA binding
DYD83_RS15705	COG0670	Belongs to the BI1 family
DYD83_RS15710	COG2920	part of a sulfur-relay system
DYD83_RS15715	COG1254	Belongs to the acylphosphatase family
DYD83_RS15720	COG3785	DNA binding
DYD83_RS15725	COG1832	CoA-binding protein
DYD83_RS15735	COG1803	Methylglyoxal synthase
DYD83_RS15740	COG0210	DNA helicase
DYD83_RS15745	COG3304	Inner membrane component domain
DYD83_RS15750	COG1289	transmembrane transporter activity
DYD83_RS15755	COG3070	regulator of competence-specific genes
DYD83_RS15760	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
DYD83_RS15765	COG2885	chlorophyll binding
DYD83_RS15765	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DYD83_RS15790	COG0667	Aldo Keto reductase
DYD83_RS15795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DYD83_RS15800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DYD83_RS15805	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DYD83_RS15810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DYD83_RS15815	COG0477	Major facilitator Superfamily
DYD83_RS15820	COG2205	protein histidine kinase activity
DYD83_RS15825	COG0745	RESPONSE REGULATOR receiver
DYD83_RS15830	COG0435	Glutathione S-transferase
DYD83_RS15835	COG0826	peptidase U32
DYD83_RS15840	COG3223	Belongs to the PsiE family
DYD83_RS15845	COG3622	Belongs to the hyi family
DYD83_RS15850	COG2211	Major facilitator Superfamily
DYD83_RS15860	COG0673	inositol 2-dehydrogenase activity
DYD83_RS15875	COG0351	phosphomethylpyrimidine kinase
DYD83_RS15880	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DYD83_RS15885	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DYD83_RS15890	COG2814	Major facilitator Superfamily
DYD83_RS15900	COG2192	nodulation
DYD83_RS15910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYD83_RS15915	COG0765	amino acid transport
DYD83_RS15925	COG0765	amino acid transport
DYD83_RS15930	COG0477	Major facilitator Superfamily
DYD83_RS15980	COG2207	Transcriptional regulator
DYD83_RS15995	COG2814	Major facilitator Superfamily
DYD83_RS16000	COG0583	DNA-binding transcription factor activity
DYD83_RS16010	COG0604	alcohol dehydrogenase
DYD83_RS16020	COG1733	regulation of RNA biosynthetic process
DYD83_RS16025	COG0519	Catalyzes the synthesis of GMP from XMP
DYD83_RS16025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DYD83_RS16030	COG0516	GMP reductase activity
DYD83_RS16030	COG0517	IMP dehydrogenase activity
DYD83_RS16035	COG1570	exodeoxyribonuclease VII activity
DYD83_RS16055	COG1160	GTP binding
DYD83_RS16060	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DYD83_RS16065	COG2976	Protein conserved in bacteria
DYD83_RS16070	COG0124	histidyl-tRNA synthetase
DYD83_RS16075	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DYD83_RS16080	COG1426	Protein conserved in bacteria
DYD83_RS16090	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DYD83_RS16095	COG0105	UTP biosynthetic process
DYD83_RS16100	COG2897	thiosulfate sulfurtransferase activity
DYD83_RS16110	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DYD83_RS16115	COG2975	iron-sulfur cluster assembly
DYD83_RS16120	COG0633	Ferredoxin
DYD83_RS16125	COG0443	Heat shock 70 kDa protein
DYD83_RS16130	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DYD83_RS16135	COG0316	Belongs to the HesB IscA family
DYD83_RS16140	COG0822	iron-sulfur transferase activity
DYD83_RS16150	COG1959	2 iron, 2 sulfur cluster binding
DYD83_RS16155	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
DYD83_RS16160	COG0483	inositol monophosphate 1-phosphatase activity
DYD83_RS16170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DYD83_RS16175	COG1120	ATPase activity
DYD83_RS16185	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
DYD83_RS16190	COG3683	transport system, periplasmic component
DYD83_RS16195	COG2814	Major facilitator Superfamily
DYD83_RS16200	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DYD83_RS16205	COG1017	nitric oxide dioxygenase activity
DYD83_RS16205	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DYD83_RS16210	COG3866	Pectate lyase
DYD83_RS16230	COG4677	pectinesterase activity
DYD83_RS16235	COG0347	Belongs to the P(II) protein family
DYD83_RS16240	COG2204	response regulator
DYD83_RS16245	COG3170	Tfp pilus assembly protein FimV
DYD83_RS16250	COG2205	protein histidine kinase activity
DYD83_RS16255	COG0047	phosphoribosylformylglycinamidine synthase activity
DYD83_RS16255	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DYD83_RS16260	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
DYD83_RS16270	COG0560	Phosphoserine phosphatase
DYD83_RS16275	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DYD83_RS16300	COG2200	EAL domain
DYD83_RS16305	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DYD83_RS16310	COG0736	holo-[acyl-carrier-protein] synthase activity
DYD83_RS16315	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DYD83_RS16320	COG1381	Involved in DNA repair and RecF pathway recombination
DYD83_RS16325	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DYD83_RS16330	COG0571	ribonuclease III activity
DYD83_RS16340	COG0481	GTPase activity
DYD83_RS16345	COG3086	response to oxidative stress
DYD83_RS16350	COG3026	antisigma factor binding
DYD83_RS16365	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DYD83_RS16370	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DYD83_RS16375	COG0513	Belongs to the DEAD box helicase family
DYD83_RS16385	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
DYD83_RS16390	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DYD83_RS16405	COG2873	o-acetylhomoserine
DYD83_RS16410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DYD83_RS16440	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DYD83_RS16445	COG4208	sulfate ABC transporter
DYD83_RS16450	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DYD83_RS16455	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DYD83_RS16460	COG3835	regulator
DYD83_RS16465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DYD83_RS16470	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DYD83_RS16475	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DYD83_RS16480	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DYD83_RS16500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DYD83_RS16505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DYD83_RS16510	COG1120	ATPase activity
DYD83_RS16515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DYD83_RS16520	COG1643	Atp-dependent helicase
DYD83_RS16525	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DYD83_RS16530	COG1489	DNA binding
DYD83_RS16535	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DYD83_RS16540	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DYD83_RS16545	COG0617	tRNA 3'-terminal CCA addition
DYD83_RS16550	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DYD83_RS16555	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DYD83_RS16560	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DYD83_RS16565	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DYD83_RS16570	COG0842	Transport permease protein
DYD83_RS16575	COG1131	(ABC) transporter
DYD83_RS16580	COG0288	reversible hydration of carbon dioxide
DYD83_RS16585	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DYD83_RS16600	COG3842	ATPase activity
DYD83_RS16615	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DYD83_RS16620	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DYD83_RS16630	COG1780	Probably involved in ribonucleotide reductase function
DYD83_RS16640	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DYD83_RS16650	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DYD83_RS16655	COG0328	RNA-DNA hybrid ribonuclease activity
DYD83_RS16660	COG2226	methyltransferase
DYD83_RS16665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DYD83_RS16670	COG1388	LysM domain
DYD83_RS16670	COG0741	lytic transglycosylase activity
DYD83_RS16675	COG3021	interspecies interaction between organisms
DYD83_RS16705	COG0542	response to heat
DYD83_RS16710	COG1496	oxidoreductase activity
DYD83_RS16715	COG0564	pseudouridine synthase activity
DYD83_RS16720	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DYD83_RS16725	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DYD83_RS16730	COG0077	Prephenate dehydratase
DYD83_RS16730	COG1605	Chorismate mutase
DYD83_RS16735	COG0287	Prephenate dehydrogenase
DYD83_RS16735	COG1605	Chorismate mutase
DYD83_RS16740	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DYD83_RS16755	COG0335	large ribosomal subunit rRNA binding
DYD83_RS16760	COG0336	Belongs to the RNA methyltransferase TrmD family
DYD83_RS16765	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DYD83_RS16770	COG0228	four-way junction DNA binding
DYD83_RS16775	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DYD83_RS16780	COG4137	Cytochrome C assembly protein
DYD83_RS16785	COG1854	S-ribosylhomocysteine lyase activity
DYD83_RS16790	COG2918	glutathione biosynthetic process
DYD83_RS16795	COG1238	metal cluster binding
DYD83_RS16800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DYD83_RS16825	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DYD83_RS16830	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DYD83_RS16835	COG2137	regulation of response to DNA damage stimulus
DYD83_RS16840	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DYD83_RS16855	COG3038	cytochrome b561
DYD83_RS16905	COG1879	ABC-type sugar transport system periplasmic component
DYD83_RS16910	COG1129	ABC transporter
DYD83_RS16915	COG1172	Belongs to the binding-protein-dependent transport system permease family
DYD83_RS16920	COG1172	Belongs to the binding-protein-dependent transport system permease family
DYD83_RS16925	COG0688	phosphatidylethanolamine metabolic process
DYD83_RS16935	COG2207	Transcriptional regulator
DYD83_RS16945	COG0523	cobalamin synthesis protein
DYD83_RS16950	COG2879	small protein
DYD83_RS16955	COG1966	Carbon starvation protein
DYD83_RS16965	COG3275	phosphorelay sensor kinase activity
DYD83_RS16975	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DYD83_RS16995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DYD83_RS17000	COG1696	Membrane protein involved in D-alanine export
DYD83_RS17025	COG2161	toxin-antitoxin pair type II binding
DYD83_RS17030	COG0582	viral genome integration into host DNA
DYD83_RS17040	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DYD83_RS17045	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DYD83_RS17055	COG2199	diguanylate cyclase activity
DYD83_RS17065	COG1073	alpha beta
DYD83_RS17070	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DYD83_RS17080	COG2195	Cleaves the N-terminal amino acid of tripeptides
DYD83_RS17085	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DYD83_RS17090	COG3034	peptidoglycan biosynthetic process
DYD83_RS17095	COG0121	glutamine amidotransferase
DYD83_RS17100	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DYD83_RS17105	COG1960	acyl-CoA dehydrogenase activity
DYD83_RS17110	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
DYD83_RS17115	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DYD83_RS17120	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
DYD83_RS17125	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
DYD83_RS17130	COG0235	Class ii aldolase
DYD83_RS17135	COG0436	Aminotransferase
DYD83_RS17150	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DYD83_RS17160	COG0765	amino acid transport
DYD83_RS17165	COG0765	amino acid transport
DYD83_RS17215	COG1953	Uracil, thiamine, allantoin
DYD83_RS17230	COG4175	Glycine betaine
DYD83_RS17235	COG4176	ABC-type proline glycine betaine transport system permease component
DYD83_RS17240	COG2113	Glycine betaine
DYD83_RS17245	COG2814	Major facilitator Superfamily
DYD83_RS17250	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DYD83_RS17260	COG1846	Transcriptional regulator
DYD83_RS17265	COG1566	PFAM secretion protein HlyD family protein
DYD83_RS17270	COG2814	Major facilitator Superfamily
DYD83_RS17275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DYD83_RS17280	COG3118	belongs to the thioredoxin family
DYD83_RS17285	COG3148	PFAM DTW domain containing protein
DYD83_RS17290	COG0045	succinate-CoA ligase (ADP-forming) activity
DYD83_RS17290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DYD83_RS17290	COG1042	CoA-binding domain protein
DYD83_RS17295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DYD83_RS17300	COG5544	Lipoprotein
DYD83_RS17305	COG0477	Major facilitator Superfamily
DYD83_RS17345	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DYD83_RS17355	COG2011	ABC-type metal ion transport system permease component
DYD83_RS17360	COG1464	Belongs to the NlpA lipoprotein family
DYD83_RS17370	COG1720	tRNA m6t6A37 methyltransferase activity
DYD83_RS17375	COG0442	prolyl-tRNA aminoacylation
DYD83_RS17385	COG4942	peptidase
DYD83_RS17385	COG1388	LysM domain
DYD83_RS17390	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DYD83_RS17395	COG0585	pseudouridine synthase activity
DYD83_RS17400	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DYD83_RS17405	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DYD83_RS17410	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DYD83_RS17420	COG0529	Catalyzes the synthesis of activated sulfate
DYD83_RS17425	COG2895	sulfate adenylyltransferase (ATP) activity
DYD83_RS17435	COG1648	precorrin-2 dehydrogenase activity
DYD83_RS17435	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DYD83_RS17440	COG0175	sulfate reduction
DYD83_RS17445	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DYD83_RS17450	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DYD83_RS17470	COG0720	synthase
DYD83_RS17475	COG0602	queuosine metabolic process
DYD83_RS17485	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DYD83_RS17500	COG0504	CTP synthase activity
DYD83_RS17505	COG3956	TIGRFAM MazG family protein
DYD83_RS17510	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DYD83_RS17515	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DYD83_RS17525	COG1929	Belongs to the glycerate kinase type-1 family
DYD83_RS17530	COG2084	Dehydrogenase
DYD83_RS17540	COG4948	Mandelate Racemase Muconate Lactonizing
DYD83_RS17545	COG4948	Mandelate Racemase Muconate Lactonizing
DYD83_RS17550	COG2271	Major facilitator Superfamily
DYD83_RS17555	COG2721	sulfolactate sulfo-lyase activity
DYD83_RS17560	COG0840	transmembrane signaling receptor activity
DYD83_RS17580	COG3530	Putative quorum-sensing-regulated virulence factor
DYD83_RS17585	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DYD83_RS17590	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DYD83_RS17590	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DYD83_RS17595	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DYD83_RS17600	COG3025	triphosphatase activity
DYD83_RS17605	COG4991	sh3 domain protein
DYD83_RS17610	COG0617	tRNA 3'-terminal CCA addition
DYD83_RS17615	COG1968	undecaprenyl-diphosphatase activity
DYD83_RS17620	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DYD83_RS17625	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DYD83_RS17635	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DYD83_RS17640	COG2105	PFAM AIG2 family protein
DYD83_RS17650	COG0729	surface antigen
DYD83_RS17655	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DYD83_RS17660	COG1253	flavin adenine dinucleotide binding
DYD83_RS17670	COG1218	3'(2'),5'-bisphosphate nucleotidase
DYD83_RS17675	COG0737	Belongs to the 5'-nucleotidase family
DYD83_RS17680	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
DYD83_RS17690	COG0545	Peptidyl-prolyl cis-trans isomerase
DYD83_RS17695	COG3061	Opacity-associated protein A
DYD83_RS17705	COG0359	binds to the 23S rRNA
DYD83_RS17710	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DYD83_RS17715	COG2965	DNA replication, synthesis of RNA primer
DYD83_RS17725	COG1073	alpha beta
DYD83_RS17730	COG0840	transmembrane signaling receptor activity
DYD83_RS17745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DYD83_RS17750	COG0557	exoribonuclease II activity
DYD83_RS17755	COG1959	2 iron, 2 sulfur cluster binding
DYD83_RS17770	COG0402	S-adenosylhomocysteine deaminase activity
DYD83_RS17790	COG2805	Type II/IV secretion system protein
DYD83_RS17795	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DYD83_RS17800	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DYD83_RS17805	COG0762	integral membrane protein
DYD83_RS17810	COG1872	DUF167
DYD83_RS17815	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DYD83_RS17820	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DYD83_RS17830	COG2153	protein acetylation
DYD83_RS17835	COG0477	Major facilitator Superfamily
DYD83_RS17840	COG0318	PFAM AMP-dependent synthetase and ligase
DYD83_RS17840	COG0204	Acyl-transferase
DYD83_RS17845	COG2723	6-phospho-beta-galactosidase activity
DYD83_RS17850	COG2723	6-phospho-beta-galactosidase activity
DYD83_RS17855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DYD83_RS17855	COG1263	PTS System
DYD83_RS17855	COG2190	(PTS) system
DYD83_RS17860	COG3711	transcriptional antiterminator
DYD83_RS17870	COG1609	Transcriptional regulator
DYD83_RS17880	COG2186	Transcriptional regulator
DYD83_RS17885	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DYD83_RS17890	COG2723	6-phospho-beta-galactosidase activity
DYD83_RS17895	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DYD83_RS17900	COG1447	Phosphotransferase system cellobiose-specific component IIA
DYD83_RS17905	COG1609	Transcriptional regulator
DYD83_RS17915	COG0583	DNA-binding transcription factor activity
DYD83_RS17920	COG3842	ATPase activity
DYD83_RS17930	COG4149	molybdate abc transporter
DYD83_RS17935	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DYD83_RS17955	COG5642	Protein of unknown function (DUF2384)
DYD83_RS17960	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DYD83_RS17970	COG2124	cytochrome p450
DYD83_RS17985	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DYD83_RS18005	COG1522	sequence-specific DNA binding
DYD83_RS18015	COG1448	Aminotransferase
DYD83_RS18040	COG1203	CRISPR-associated helicase, Cas3
DYD83_RS18045	COG1518	maintenance of DNA repeat elements
DYD83_RS18050	COG0840	transmembrane signaling receptor activity
DYD83_RS18060	COG2199	diguanylate cyclase activity
DYD83_RS18060	COG2203	Gaf domain
DYD83_RS18065	COG0432	Pfam Uncharacterised protein family UPF0047
DYD83_RS18070	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DYD83_RS18145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DYD83_RS18245	COG1609	Transcriptional regulator
DYD83_RS18250	COG0395	ABC-type sugar transport system, permease component
DYD83_RS18255	COG1175	transmembrane transport
DYD83_RS18260	COG3842	ATPase activity
DYD83_RS18265	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DYD83_RS18285	COG2971	BadF BadG BcrA BcrD
DYD83_RS18295	COG0725	ABC transporter, periplasmic molybdate-binding protein
DYD83_RS18300	COG1121	(ABC) transporter
DYD83_RS18305	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DYD83_RS18310	COG0803	Belongs to the bacterial solute-binding protein 9 family
DYD83_RS18315	COG2368	4-hydroxyphenylacetate
DYD83_RS18355	COG1349	DNA-binding transcription factor activity
DYD83_RS18360	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DYD83_RS18365	COG3395	kinase activity
DYD83_RS18370	COG1454	alcohol dehydrogenase
DYD83_RS18375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DYD83_RS18390	COG2731	YhcH YjgK YiaL family protein
DYD83_RS18400	COG0861	Integral membrane protein TerC family
DYD83_RS18405	COG3112	Uncharacterised protein family (UPF0231)
DYD83_RS18420	COG4771	TonB-dependent receptor
DYD83_RS18425	COG4977	sequence-specific DNA binding
DYD83_RS18430	COG2079	MmgE PrpD family protein
DYD83_RS18440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DYD83_RS18445	COG0508	dehydrogenase complex catalyzes the overall conversion of
DYD83_RS18450	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DYD83_RS18460	COG1113	amino acid transport
DYD83_RS18465	COG3725	Membrane protein required for beta-lactamase induction
DYD83_RS18470	COG3023	N-Acetylmuramoyl-L-alanine amidase
DYD83_RS18475	COG3248	Nucleoside-binding outer membrane protein
DYD83_RS18485	COG4969	Belongs to the N-Me-Phe pilin family
DYD83_RS18490	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DYD83_RS18495	COG1459	type II secretion system
DYD83_RS18500	COG0516	GMP reductase activity
DYD83_RS18505	COG0237	dephospho-CoA kinase activity
DYD83_RS18510	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
DYD83_RS18515	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DYD83_RS18520	COG0494	nUDIX hydrolase
DYD83_RS18525	COG0653	protein targeting
DYD83_RS18540	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DYD83_RS18545	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DYD83_RS18550	COG0849	cell division
DYD83_RS18555	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DYD83_RS18560	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DYD83_RS18565	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DYD83_RS18570	COG0772	Belongs to the SEDS family
DYD83_RS18575	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DYD83_RS18580	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DYD83_RS18585	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DYD83_RS18590	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DYD83_RS18595	COG0768	penicillin binding
DYD83_RS18600	COG3116	cell division
DYD83_RS18605	COG0275	rRNA processing
DYD83_RS18610	COG2001	Belongs to the MraZ family
DYD83_RS18630	COG0028	Belongs to the TPP enzyme family
DYD83_RS18635	COG1022	Amp-dependent synthetase and ligase
DYD83_RS18645	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DYD83_RS18650	COG0473	3-isopropylmalate dehydrogenase activity
DYD83_RS18660	COG0066	3-isopropylmalate dehydratase activity
DYD83_RS18675	COG3033	Beta-eliminating lyase
DYD83_RS18685	COG4533	DNA binding
DYD83_RS18695	COG1178	ABC-type Fe3 transport system permease component
DYD83_RS18700	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
DYD83_RS18710	COG0028	Belongs to the TPP enzyme family
DYD83_RS18715	COG0440	acetolactate synthase activity
DYD83_RS18720	COG0586	Pfam SNARE associated Golgi protein
DYD83_RS18750	COG3157	Type VI secretion system effector, Hcp
DYD83_RS18760	COG0411	ABC transporter
DYD83_RS18780	COG0417	DNA replication proofreading
DYD83_RS18785	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DYD83_RS18790	COG0564	pseudouridine synthase activity
DYD83_RS18795	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DYD83_RS18800	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DYD83_RS18805	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DYD83_RS18810	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DYD83_RS18815	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DYD83_RS18820	COG2967	ApaG domain
DYD83_RS18825	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DYD83_RS18835	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DYD83_RS18840	COG3610	response to peptide
DYD83_RS18845	COG2966	Psort location CytoplasmicMembrane, score
DYD83_RS18850	COG1280	lysine exporter protein (LysE YggA)
DYD83_RS18855	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DYD83_RS18860	COG0505	Belongs to the CarA family
DYD83_RS18875	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DYD83_RS18880	COG1047	Peptidyl-prolyl cis-trans
DYD83_RS18885	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DYD83_RS18890	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DYD83_RS18895	COG0196	riboflavin kinase activity
DYD83_RS18900	COG0268	Binds directly to 16S ribosomal RNA
DYD83_RS18905	COG0583	DNA-binding transcription factor activity
DYD83_RS18910	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DYD83_RS18915	COG0484	heat shock protein binding
DYD83_RS18925	COG1584	GPR1 FUN34 yaaH family protein
DYD83_RS18935	COG0521	Mo-molybdopterin cofactor biosynthetic process
DYD83_RS18940	COG3706	GGDEF domain
DYD83_RS18945	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DYD83_RS18950	COG3022	response to hydroperoxide
DYD83_RS18960	COG0083	homoserine kinase activity
DYD83_RS18970	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
DYD83_RS18975	COG0745	RESPONSE REGULATOR receiver
DYD83_RS18980	COG3045	CreA protein
DYD83_RS18985	COG3708	Transcriptional regulator
DYD83_RS18985	COG2207	Transcriptional regulator
DYD83_RS18990	COG0406	alpha-ribazole phosphatase activity
DYD83_RS18995	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
DYD83_RS19000	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
DYD83_RS19010	COG0488	(ABC) transporter
DYD83_RS19015	COG0840	transmembrane signaling receptor activity
DYD83_RS19020	COG0583	DNA-binding transcription factor activity
DYD83_RS19025	COG0604	alcohol dehydrogenase
DYD83_RS19030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DYD83_RS19035	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DYD83_RS19040	COG0583	DNA-binding transcription factor activity
DYD83_RS19045	COG2968	Membrane
DYD83_RS19050	COG1414	Transcriptional regulator
DYD83_RS19055	COG0668	transmembrane transport
DYD83_RS19065	COG0126	phosphoglycerate kinase activity
DYD83_RS19070	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DYD83_RS19075	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DYD83_RS19080	COG0738	Major facilitator superfamily
DYD83_RS19085	COG1166	arginine decarboxylase activity
DYD83_RS19100	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DYD83_RS19105	COG3091	SprT-like family
DYD83_RS19110	COG2356	endonuclease I
DYD83_RS19115	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DYD83_RS19120	COG0189	ligase activity
DYD83_RS19125	COG1678	Uncharacterized ACR, COG1678
DYD83_RS19130	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DYD83_RS19135	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DYD83_RS19140	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DYD83_RS19145	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DYD83_RS19150	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
DYD83_RS19155	COG0330	HflC and HflK could
DYD83_RS19160	COG0330	HflC and HflK could
DYD83_RS19165	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DYD83_RS19170	COG1923	regulation of RNA biosynthetic process
DYD83_RS19175	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DYD83_RS19180	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DYD83_RS19190	COG0802	atpase or kinase
DYD83_RS19195	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DYD83_RS19195	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DYD83_RS19205	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DYD83_RS19225	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DYD83_RS19240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DYD83_RS19250	COG0438	transferase activity, transferring glycosyl groups
DYD83_RS19250	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DYD83_RS19275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DYD83_RS19280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DYD83_RS19300	COG0765	amino acid transport
DYD83_RS19305	COG1126	abc transporter atp-binding protein
DYD83_RS19315	COG1764	response to oxidative stress
DYD83_RS19320	COG1846	Transcriptional regulator
DYD83_RS19325	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DYD83_RS19330	COG1473	amidohydrolase
DYD83_RS19340	COG0583	DNA-binding transcription factor activity
DYD83_RS19345	COG0840	transmembrane signaling receptor activity
DYD83_RS19360	COG3604	Transcriptional regulator
DYD83_RS19365	COG2205	protein histidine kinase activity
DYD83_RS19380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DYD83_RS19430	COG3157	Type VI secretion system effector, Hcp
DYD83_RS19450	COG0840	transmembrane signaling receptor activity
DYD83_RS19465	COG3550	peptidyl-serine autophosphorylation
DYD83_RS19525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DYD83_RS19580	COG1028	Short-chain dehydrogenase reductase Sdr
DYD83_RS19580	COG3321	synthase
DYD83_RS19580	COG4221	oxidoreductase activity
DYD83_RS19580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DYD83_RS19585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DYD83_RS19595	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DYD83_RS19600	COG1162	GTPase activity
DYD83_RS19605	COG0688	phosphatidylethanolamine metabolic process
DYD83_RS19610	COG1511	domain protein
DYD83_RS19610	COG3264	Mechanosensitive ion channel
DYD83_RS19615	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
DYD83_RS19620	COG1053	succinate dehydrogenase
DYD83_RS19625	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DYD83_RS19630	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
DYD83_RS19635	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
DYD83_RS19640	COG3040	lipid binding
DYD83_RS19650	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DYD83_RS19655	COG1509	lysine 2,3-aminomutase activity
DYD83_RS19670	COG3547	Transposase (IS116 IS110 IS902 family)
DYD83_RS19680	COG0166	Belongs to the GPI family
DYD83_RS19685	COG0527	aspartate kinase activity
DYD83_RS19695	COG1283	sodium-dependent phosphate transmembrane transporter activity
DYD83_RS19700	COG0471	metal ion transport
DYD83_RS19715	COG1410	methionine synthase
DYD83_RS19715	COG0646	methionine synthase
DYD83_RS19725	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
DYD83_RS19735	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DYD83_RS19740	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
DYD83_RS19770	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DYD83_RS19780	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DYD83_RS19785	COG0009	L-threonylcarbamoyladenylate synthase
DYD83_RS19790	COG0551	DNA topoisomerase type I activity
DYD83_RS19795	COG2922	Belongs to the Smg family
DYD83_RS19800	COG0758	DNA mediated transformation
DYD83_RS19805	COG0242	peptide deformylase activity
DYD83_RS19810	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DYD83_RS19815	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DYD83_RS19815	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DYD83_RS19825	COG1970	mechanosensitive ion channel activity
DYD83_RS19840	COG0203	ribosomal protein L17
DYD83_RS19850	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DYD83_RS19860	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DYD83_RS19865	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DYD83_RS19870	COG0201	protein transport
DYD83_RS19875	COG0200	Binds to the 23S rRNA
DYD83_RS19880	COG1841	ribosomal large subunit assembly
DYD83_RS19885	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DYD83_RS19895	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DYD83_RS19905	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DYD83_RS19910	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DYD83_RS19935	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DYD83_RS19945	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DYD83_RS19950	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DYD83_RS19955	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DYD83_RS19960	COG0089	rRNA binding
DYD83_RS19965	COG0088	Forms part of the polypeptide exit tunnel
DYD83_RS19970	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DYD83_RS19975	COG0051	transcription antitermination factor activity, RNA binding
DYD83_RS19990	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DYD83_RS19995	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DYD83_RS20000	COG0049	tRNA binding
DYD83_RS20005	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DYD83_RS20010	COG2168	tRNA wobble position uridine thiolation
DYD83_RS20015	COG2923	Belongs to the DsrF TusC family
DYD83_RS20020	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
DYD83_RS20025	COG2964	Protein conserved in bacteria
DYD83_RS20030	COG2194	sulfuric ester hydrolase activity
DYD83_RS20035	COG0745	RESPONSE REGULATOR receiver
DYD83_RS20040	COG0642	Histidine kinase
DYD83_RS20045	COG0545	Peptidyl-prolyl cis-trans isomerase
DYD83_RS20050	COG2900	Belongs to the SlyX family
DYD83_RS20060	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DYD83_RS20070	COG2140	Oxalate decarboxylase
DYD83_RS20075	COG1047	Peptidyl-prolyl cis-trans
DYD83_RS20080	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
DYD83_RS20085	COG0475	glutathione-regulated potassium exporter activity
DYD83_RS20085	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DYD83_RS20090	COG2249	NAD(P)H dehydrogenase (quinone) activity
DYD83_RS20095	COG0488	(ABC) transporter
DYD83_RS20105	COG0429	hydrolase of the alpha beta-hydrolase fold
DYD83_RS20115	COG3954	Phosphoribulokinase
DYD83_RS20120	COG1765	OsmC-like protein
DYD83_RS20140	COG2207	Transcriptional regulator
DYD83_RS20140	COG4753	response regulator
DYD83_RS20155	COG1404	Belongs to the peptidase S8 family
DYD83_RS20160	COG3179	chitinase
DYD83_RS20180	COG0076	glutamate decarboxylase activity
DYD83_RS20200	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DYD83_RS20205	COG4948	Mandelate Racemase Muconate Lactonizing
DYD83_RS20215	COG0546	phosphoglycolate phosphatase activity
DYD83_RS20220	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DYD83_RS20235	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DYD83_RS20240	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DYD83_RS20245	COG4796	Type ii and iii secretion system protein
DYD83_RS20270	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DYD83_RS20275	COG0494	nUDIX hydrolase
DYD83_RS20285	COG1011	Hydrolase
DYD83_RS20290	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DYD83_RS20295	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DYD83_RS20300	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
DYD83_RS20315	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DYD83_RS20325	COG2183	response to ionizing radiation
DYD83_RS20335	COG2267	carboxylic ester hydrolase activity
DYD83_RS20345	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DYD83_RS20345	COG0316	Belongs to the HesB IscA family
DYD83_RS20350	COG1640	4-alpha-glucanotransferase
DYD83_RS20355	COG0058	SHG alpha-glucan phosphorylase activity
DYD83_RS20360	COG1349	DNA-binding transcription factor activity
DYD83_RS20365	COG0705	Rhomboid family
DYD83_RS20370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DYD83_RS20380	COG2731	YhcH YjgK YiaL family protein
DYD83_RS20385	COG2271	Major facilitator Superfamily
DYD83_RS20390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DYD83_RS20395	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DYD83_RS20405	COG0058	SHG alpha-glucan phosphorylase activity
DYD83_RS20410	COG0297	glycogen (starch) synthase activity
DYD83_RS20415	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DYD83_RS20430	COG3275	phosphorelay sensor kinase activity
DYD83_RS20435	COG1278	Cold shock
DYD83_RS20445	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DYD83_RS20450	COG2095	MarC family integral membrane protein
DYD83_RS20455	COG2610	gluconate transmembrane transporter activity
DYD83_RS20460	COG3265	gluconokinase activity
DYD83_RS20465	COG1609	Transcriptional regulator
DYD83_RS20475	COG1741	Belongs to the pirin family
DYD83_RS20480	COG0247	lactate metabolic process
DYD83_RS20485	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
DYD83_RS20490	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DYD83_RS20495	COG2271	Major facilitator Superfamily
DYD83_RS20500	COG0584	glycerophosphoryl diester phosphodiesterase
DYD83_RS20505	COG0561	phosphatase activity
DYD83_RS20510	COG2267	carboxylic ester hydrolase activity
DYD83_RS20515	COG1280	lysine exporter protein (LysE YggA)
DYD83_RS20530	COG1280	lysine exporter protein (LysE YggA)
DYD83_RS20535	COG0514	ATP-dependent DNA helicase (RecQ)
DYD83_RS20540	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
DYD83_RS20545	COG2050	protein possibly involved in aromatic compounds catabolism
DYD83_RS20555	COG3180	Ammonia monooxygenase
DYD83_RS20560	COG0598	Magnesium transport protein CorA
DYD83_RS20565	COG0210	DNA helicase
DYD83_RS20570	COG1011	Hydrolase
DYD83_RS20585	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DYD83_RS20605	COG0181	hydroxymethylbilane synthase activity
DYD83_RS20610	COG1587	Uroporphyrinogen-III synthase
DYD83_RS20615	COG2959	enzyme of heme biosynthesis
DYD83_RS20620	COG3071	HemY protein
DYD83_RS20625	COG1473	amidohydrolase
DYD83_RS20630	COG1126	abc transporter atp-binding protein
DYD83_RS20635	COG0765	amino acid transport
DYD83_RS20640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYD83_RS20645	COG0456	acetyltransferase
DYD83_RS20650	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DYD83_RS20685	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
DYD83_RS20695	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DYD83_RS20700	COG2244	polysaccharide biosynthetic process
DYD83_RS20705	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DYD83_RS20715	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DYD83_RS20720	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DYD83_RS20725	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
DYD83_RS20730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DYD83_RS20735	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DYD83_RS20740	COG3118	belongs to the thioredoxin family
DYD83_RS20745	COG0513	Belongs to the DEAD box helicase family
DYD83_RS20750	COG0248	Ppx GppA phosphatase
DYD83_RS20765	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DYD83_RS20770	COG0506	proline dehydrogenase activity
DYD83_RS20770	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DYD83_RS20770	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DYD83_RS20775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DYD83_RS20785	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DYD83_RS20805	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DYD83_RS20815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DYD83_RS20820	COG3978	acetolactate synthase activity
DYD83_RS20835	COG2814	Major facilitator Superfamily
DYD83_RS20845	COG3085	chromosome segregation
DYD83_RS20850	COG0583	DNA-binding transcription factor activity
DYD83_RS20890	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DYD83_RS20900	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DYD83_RS20915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DYD83_RS20925	COG0678	peroxiredoxin activity
DYD83_RS20925	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DYD83_RS20935	COG0527	aspartate kinase activity
DYD83_RS20935	COG0460	homoserine dehydrogenase
DYD83_RS20940	COG0626	cystathionine gamma-synthase activity
DYD83_RS20945	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
DYD83_RS20955	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DYD83_RS20960	COG1609	Transcriptional regulator
DYD83_RS20965	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DYD83_RS20970	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DYD83_RS20975	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DYD83_RS20980	COG1575	Belongs to the MenA family. Type 1 subfamily
DYD83_RS20985	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DYD83_RS20990	COG3074	FtsZ-dependent cytokinesis
DYD83_RS20995	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DYD83_RS21005	COG1494	fructose-1,6-bisphosphatase
DYD83_RS21015	COG3152	Membrane
DYD83_RS21025	COG0149	triose-phosphate isomerase activity
DYD83_RS21035	COG2957	Belongs to the agmatine deiminase family
DYD83_RS21040	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DYD83_RS21050	COG0205	6-phosphofructokinase activity
DYD83_RS21055	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DYD83_RS21100	COG3678	ATP-independent chaperone mediated protein folding
DYD83_RS21105	COG0745	RESPONSE REGULATOR receiver
DYD83_RS21110	COG2205	protein histidine kinase activity
DYD83_RS21130	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DYD83_RS21140	COG0679	Auxin Efflux Carrier
DYD83_RS21145	COG0584	glycerophosphoryl diester phosphodiesterase
DYD83_RS21150	COG3842	ATPase activity
DYD83_RS21155	COG0395	ABC-type sugar transport system, permease component
DYD83_RS21160	COG1175	transmembrane transport
DYD83_RS21165	COG1653	transport
DYD83_RS21175	COG0840	transmembrane signaling receptor activity
DYD83_RS21180	COG0840	transmembrane signaling receptor activity
DYD83_RS21185	COG0840	transmembrane signaling receptor activity
DYD83_RS21190	COG0840	transmembrane signaling receptor activity
DYD83_RS21200	COG0840	transmembrane signaling receptor activity
DYD83_RS21220	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DYD83_RS21225	COG0179	Fumarylacetoacetate (FAA) hydrolase
DYD83_RS21230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DYD83_RS21240	COG0411	ABC transporter
DYD83_RS21245	COG4177	L-phenylalanine transmembrane transporter activity
DYD83_RS21250	COG0559	Belongs to the binding-protein-dependent transport system permease family
DYD83_RS21255	COG0683	leucine binding
DYD83_RS21270	COG2177	Part of the ABC transporter FtsEX involved in
DYD83_RS21275	COG2884	Cell division ATP-binding protein ftsE
DYD83_RS21280	COG0552	protein localization to endoplasmic reticulum
DYD83_RS21280	COG0552	protein localization to endoplasmic reticulum
DYD83_RS21285	COG0742	ribosomal rna small subunit methyltransferase
DYD83_RS21290	COG3776	membrane
DYD83_RS21300	COG3714	YhhN family
DYD83_RS21305	COG0425	Belongs to the sulfur carrier protein TusA family
DYD83_RS21310	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DYD83_RS21320	COG0477	Major facilitator Superfamily
DYD83_RS21325	COG1295	ribonuclease BN
DYD83_RS21330	COG1942	4-Oxalocrotonate Tautomerase
DYD83_RS21335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DYD83_RS21365	COG1301	dicarboxylic acid transport
DYD83_RS21370	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DYD83_RS21380	COG0457	Tetratricopeptide repeat
DYD83_RS21390	COG1215	transferase activity, transferring glycosyl groups
DYD83_RS21395	COG0489	protein tyrosine kinase activity
DYD83_RS21410	COG2378	regulation of single-species biofilm formation
DYD83_RS21420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DYD83_RS21440	COG4608	Belongs to the ABC transporter superfamily
DYD83_RS21445	COG0444	Belongs to the ABC transporter superfamily
DYD83_RS21450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DYD83_RS21455	COG0601	transmembrane transport
DYD83_RS21460	COG0747	negative chemotaxis
DYD83_RS21465	COG3493	citrate carrier protein
DYD83_RS21470	COG4565	transcriptional regulatory protein
DYD83_RS21475	COG3290	protein histidine kinase activity
DYD83_RS21480	COG0471	metal ion transport
DYD83_RS21485	COG0071	Belongs to the small heat shock protein (HSP20) family
DYD83_RS21490	COG0071	Belongs to the small heat shock protein (HSP20) family
DYD83_RS21495	COG5645	(Lipo)protein
DYD83_RS21505	COG0477	Major facilitator Superfamily
DYD83_RS21515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DYD83_RS21525	COG1069	ribulokinase activity
DYD83_RS21530	COG0823	Involved in the tonB-independent uptake of proteins
DYD83_RS21550	COG0561	phosphatase activity
DYD83_RS21560	COG0589	response to stress
DYD83_RS21570	COG0306	phosphate transporter
DYD83_RS21575	COG2081	HI0933 family
DYD83_RS21590	COG3842	ATPase activity
DYD83_RS21595	COG0395	ABC-type sugar transport system, permease component
DYD83_RS21635	COG0697	spore germination
DYD83_RS21655	COG3048	D-serine ammonia-lyase activity
DYD83_RS21680	COG1653	transport
DYD83_RS21690	COG1175	transmembrane transport
DYD83_RS21700	COG2814	Major facilitator Superfamily
DYD83_RS21705	COG0583	DNA-binding transcription factor activity
DYD83_RS21720	COG4221	oxidoreductase activity
DYD83_RS21735	COG2194	sulfuric ester hydrolase activity
DYD83_RS21740	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DYD83_RS21745	COG0194	GDP metabolic process
DYD83_RS21755	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DYD83_RS21760	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DYD83_RS21765	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DYD83_RS21770	COG2233	PERMEase
DYD83_RS21775	COG2982	Protein involved in outer membrane biogenesis
DYD83_RS21780	COG0456	acetyltransferase
DYD83_RS21785	COG1490	D-aminoacyl-tRNA deacylase activity
DYD83_RS21790	COG1011	Hydrolase
DYD83_RS21795	COG1217	gtp-binding protein TYPA
DYD83_RS21805	COG3852	Histidine kinase
DYD83_RS21825	COG3078	GTPase activator activity
DYD83_RS21830	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DYD83_RS21835	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DYD83_RS21835	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DYD83_RS21840	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DYD83_RS21845	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DYD83_RS21850	COG3084	Protein conserved in bacteria
DYD83_RS21860	COG1763	Mo-molybdopterin cofactor biosynthetic process
DYD83_RS21885	COG1609	Transcriptional regulator
DYD83_RS21890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DYD83_RS21895	COG1879	ABC-type sugar transport system periplasmic component
DYD83_RS21900	COG1172	Belongs to the binding-protein-dependent transport system permease family
DYD83_RS21905	COG1129	ABC transporter
DYD83_RS21910	COG1869	D-ribose catabolic process
DYD83_RS21915	COG3111	PFAM Bacterial OB fold (BOF) protein
DYD83_RS21920	COG0745	RESPONSE REGULATOR receiver
DYD83_RS21930	COG3158	transport of potassium into the cell
DYD83_RS21935	COG0714	Associated with various cellular activities
DYD83_RS21940	COG2425	protein containing a von Willebrand factor type A (vWA) domain
DYD83_RS21945	COG1522	sequence-specific DNA binding
DYD83_RS21950	COG0716	FMN binding
DYD83_RS21955	COG0445	tRNA wobble uridine modification
DYD83_RS21960	COG0357	Ribosomal RNA small subunit methyltransferase G
DYD83_RS21965	COG3312	ion transport
DYD83_RS21970	COG0356	it plays a direct role in the translocation of protons across the membrane
DYD83_RS21980	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DYD83_RS21985	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DYD83_RS21990	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DYD83_RS21995	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DYD83_RS22000	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DYD83_RS22005	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DYD83_RS22015	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DYD83_RS22020	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DYD83_RS22030	COG3706	GGDEF domain
DYD83_RS22040	COG0003	Pfam Anion-transporting ATPase
DYD83_RS22050	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DYD83_RS22055	COG0573	inorganic phosphate transmembrane transporter activity
DYD83_RS22060	COG0581	inorganic phosphate transmembrane transporter activity
DYD83_RS22065	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DYD83_RS22075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYD83_RS22080	COG0765	amino acid transport
DYD83_RS22085	COG0765	amino acid transport
DYD83_RS22090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DYD83_RS22095	COG2252	PERMEase
DYD83_RS22100	COG2091	lysine biosynthetic process via aminoadipic acid
DYD83_RS22110	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DYD83_RS22115	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DYD83_RS22115	COG0493	'glutamate synthase
DYD83_RS22140	COG0463	Glycosyl transferase, family 2
DYD83_RS22150	COG0726	polysaccharide deacetylase
DYD83_RS22155	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DYD83_RS22160	COG2076	Multidrug Resistance protein
DYD83_RS22165	COG2076	Multidrug Resistance protein
DYD83_RS22180	COG2910	NAD(P)H-binding
DYD83_RS22185	COG1733	regulation of RNA biosynthetic process
DYD83_RS22195	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DYD83_RS22205	COG1396	sequence-specific DNA binding
DYD83_RS22210	COG3550	peptidyl-serine autophosphorylation
DYD83_RS22215	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DYD83_RS22220	COG0706	membrane insertase activity
DYD83_RS22225	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DYD83_RS22230	COG0594	ribonuclease P activity
DYD83_RS22235	COG0230	Belongs to the bacterial ribosomal protein bL34 family