locus-tag	class	description
CT688_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CT688_RS00010	COG0592	DNA-directed DNA polymerase activity
CT688_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CT688_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CT688_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CT688_RS00095	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CT688_RS00100	COG1132	(ABC) transporter
CT688_RS00105	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS00110	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CT688_RS00130	COG0705	Rhomboid family
CT688_RS00130	COG0457	Tetratricopeptide repeat
CT688_RS00150	COG2815	serine threonine protein kinase
CT688_RS00150	COG0515	serine threonine protein kinase
CT688_RS00155	COG0515	serine threonine protein kinase
CT688_RS00160	COG0768	penicillin binding
CT688_RS00180	COG1716	ATPase activity
CT688_RS00190	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CT688_RS00195	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CT688_RS00210	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CT688_RS00215	COG2218	PFAM glutamate synthase alpha subunit domain protein
CT688_RS00220	COG0069	glutamate synthase activity
CT688_RS00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CT688_RS00255	COG3387	PFAM Glycoside hydrolase 15-related
CT688_RS00260	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS00265	COG1960	acyl-CoA dehydrogenase activity
CT688_RS00285	COG0596	Alpha beta hydrolase
CT688_RS00305	COG1960	acyl-CoA dehydrogenase activity
CT688_RS00330	COG2353	YceI-like domain
CT688_RS00345	COG2072	flavoprotein involved in K transport
CT688_RS00355	COG0300	oxidoreductase activity
CT688_RS00360	COG0662	Cupin 2, conserved barrel domain protein
CT688_RS00385	COG2610	gluconate transmembrane transporter activity
CT688_RS00410	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CT688_RS00420	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CT688_RS00420	COG2169	Transcriptional regulator
CT688_RS00425	COG1280	lysine exporter protein (LysE YggA)
CT688_RS00435	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CT688_RS00460	COG1074	ATP-dependent DNA helicase activity
CT688_RS00470	COG1309	transcriptional regulator
CT688_RS00530	COG1064	alcohol dehydrogenase
CT688_RS00535	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS00540	COG2072	flavoprotein involved in K transport
CT688_RS00550	COG0318	PFAM AMP-dependent synthetase and ligase
CT688_RS00565	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CT688_RS00570	COG1115	amino acid carrier protein
CT688_RS00580	COG2826	transposase and inactivated derivatives, IS30 family
CT688_RS00590	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CT688_RS00595	COG0175	sulfate reduction
CT688_RS00600	COG1648	precorrin-2 dehydrogenase activity
CT688_RS00600	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CT688_RS00640	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CT688_RS00645	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CT688_RS00665	COG1403	HNH endonuclease
CT688_RS00675	COG0521	Mo-molybdopterin cofactor biosynthetic process
CT688_RS00675	COG0315	cyclic pyranopterin monophosphate synthase activity
CT688_RS00680	COG1902	pentaerythritol trinitrate reductase activity
CT688_RS00695	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CT688_RS00705	COG2233	PERMEase
CT688_RS00725	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CT688_RS00725	COG1017	nitric oxide dioxygenase activity
CT688_RS00730	COG1959	2 iron, 2 sulfur cluster binding
CT688_RS00735	COG1492	cobalamin metabolic process
CT688_RS00775	COG1797	cobyrinic acid a,c-diamide synthase activity
CT688_RS00800	COG1309	transcriptional regulator
CT688_RS00815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CT688_RS00820	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CT688_RS00825	COG1960	acyl-CoA dehydrogenase activity
CT688_RS00830	COG1024	Enoyl-CoA hydratase
CT688_RS00845	COG0477	Major facilitator Superfamily
CT688_RS00885	COG3708	Transcriptional regulator
CT688_RS00885	COG2207	Transcriptional regulator
CT688_RS00890	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CT688_RS00915	COG0310	cobalt ion transport
CT688_RS00930	COG1122	ATPase activity
CT688_RS00960	COG3226	Transcriptional regulator
CT688_RS00985	COG3340	Belongs to the peptidase S51 family
CT688_RS00990	COG0657	acetylesterase activity
CT688_RS00995	COG0778	Nitroreductase
CT688_RS01010	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CT688_RS01025	COG1120	ATPase activity
CT688_RS01030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CT688_RS01045	COG0746	molybdenum cofactor guanylyltransferase activity
CT688_RS01055	COG0477	Major facilitator Superfamily
CT688_RS01065	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CT688_RS01075	COG1045	serine acetyltransferase
CT688_RS01080	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CT688_RS01120	COG2197	response regulator
CT688_RS01145	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CT688_RS01145	COG0069	glutamate synthase activity
CT688_RS01155	COG1929	Belongs to the glycerate kinase type-1 family
CT688_RS01190	COG0067	glutamate synthase
CT688_RS01190	COG0069	glutamate synthase activity
CT688_RS01190	COG0070	glutamate synthase
CT688_RS01205	COG2501	S4 domain
CT688_RS01220	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CT688_RS01230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CT688_RS01245	COG0789	Transcriptional regulator
CT688_RS01250	COG1012	belongs to the aldehyde dehydrogenase family
CT688_RS01285	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CT688_RS01290	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CT688_RS01300	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CT688_RS01305	COG1278	Cold shock
CT688_RS01320	COG0584	glycerophosphoryl diester phosphodiesterase
CT688_RS01335	COG1316	TRANSCRIPTIONal
CT688_RS01355	COG0077	Prephenate dehydratase
CT688_RS01380	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CT688_RS01395	COG0561	phosphatase activity
CT688_RS01415	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CT688_RS01420	COG1216	Glycosyl transferase, family 2
CT688_RS01425	COG0671	phosphoesterase, PA-phosphatase related
CT688_RS01430	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CT688_RS01435	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CT688_RS01445	COG5479	isomerase activity
CT688_RS01445	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CT688_RS01455	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CT688_RS01465	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CT688_RS01465	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CT688_RS01465	COG3321	synthase
CT688_RS01470	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CT688_RS01490	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS01495	COG0277	FAD linked oxidase domain protein
CT688_RS01510	COG1216	Glycosyl transferase, family 2
CT688_RS01535	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CT688_RS01550	COG1216	Glycosyl transferase, family 2
CT688_RS01565	COG2130	NADP-dependent
CT688_RS01585	COG3321	synthase
CT688_RS01585	COG0604	alcohol dehydrogenase
CT688_RS01585	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS01620	COG0737	Belongs to the 5'-nucleotidase family
CT688_RS01640	COG0697	spore germination
CT688_RS01685	COG0287	Prephenate dehydrogenase
CT688_RS01715	COG0343	queuine tRNA-ribosyltransferase activity
CT688_RS01730	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CT688_RS01765	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CT688_RS01770	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CT688_RS01775	COG1034	ATP synthesis coupled electron transport
CT688_RS01790	COG0649	NAD binding
CT688_RS01800	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CT688_RS01825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CT688_RS01840	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CT688_RS01865	COG1234	tRNA 3'-trailer cleavage
CT688_RS01870	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CT688_RS01875	COG1414	Transcriptional regulator
CT688_RS01880	COG3971	2-oxopent-4-enoate hydratase activity
CT688_RS01890	COG1942	4-Oxalocrotonate Tautomerase
CT688_RS01915	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CT688_RS01940	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CT688_RS01945	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CT688_RS01955	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CT688_RS01960	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CT688_RS01965	COG1950	PFAM Membrane protein of
CT688_RS01990	COG0697	spore germination
CT688_RS02015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CT688_RS02020	COG0477	Major facilitator Superfamily
CT688_RS02025	COG0066	3-isopropylmalate dehydratase activity
CT688_RS02030	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CT688_RS02040	COG1414	Transcriptional regulator
CT688_RS02045	COG1476	TRANSCRIPTIONal
CT688_RS02060	COG2850	peptidyl-arginine hydroxylation
CT688_RS02095	COG1484	DNA-dependent DNA replication
CT688_RS02185	COG1484	DNA-dependent DNA replication
CT688_RS02225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CT688_RS02235	COG0174	glutamine synthetase
CT688_RS02240	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CT688_RS02245	COG0156	8-amino-7-oxononanoate synthase activity
CT688_RS02250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CT688_RS02255	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CT688_RS02280	COG0446	pyridine nucleotide-disulphide oxidoreductase
CT688_RS02280	COG1902	pentaerythritol trinitrate reductase activity
CT688_RS02300	COG0589	response to stress
CT688_RS02330	COG0651	ATP synthesis coupled electron transport
CT688_RS02335	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CT688_RS02335	COG2111	Na H antiporter
CT688_RS02340	COG0651	ATP synthesis coupled electron transport
CT688_RS02360	COG1320	monovalent cation:proton antiporter activity
CT688_RS02370	COG2239	Acts as a magnesium transporter
CT688_RS02385	COG1863	multisubunit Na H antiporter MnhE subunit
CT688_RS02390	COG0651	ATP synthesis coupled electron transport
CT688_RS02395	COG1006	Multisubunit Na H antiporter MnhC subunit
CT688_RS02400	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CT688_RS02400	COG2111	Na H antiporter
CT688_RS02455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CT688_RS02470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CT688_RS02495	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CT688_RS02550	COG1205	dead DEAH box helicase
CT688_RS02550	COG1111	helicase
CT688_RS02570	COG1013	pyruvate-flavodoxin oxidoreductase activity
CT688_RS02580	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CT688_RS02580	COG1754	DNA topoisomerase type I activity
CT688_RS02590	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CT688_RS02600	COG1024	Enoyl-CoA hydratase
CT688_RS02665	COG1215	transferase activity, transferring glycosyl groups
CT688_RS02705	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS02715	COG1024	Enoyl-CoA hydratase
CT688_RS02720	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CT688_RS02725	COG2027	D-alanyl-D-alanine carboxypeptidase
CT688_RS02730	COG0037	tRNA processing
CT688_RS02735	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CT688_RS02740	COG0492	ferredoxin-NADP+ reductase activity
CT688_RS02750	COG3546	catalase activity
CT688_RS02760	COG0318	PFAM AMP-dependent synthetase and ligase
CT688_RS02765	COG1595	DNA-templated transcription, initiation
CT688_RS02780	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CT688_RS02785	COG0302	gtp cyclohydrolase
CT688_RS02790	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CT688_RS02795	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CT688_RS02820	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CT688_RS02825	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CT688_RS02830	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CT688_RS02840	COG3384	dioxygenase
CT688_RS02850	COG2066	Belongs to the glutaminase family
CT688_RS02855	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CT688_RS02880	COG1643	Atp-dependent helicase
CT688_RS02905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CT688_RS02930	COG1194	a g-specific adenine glycosylase
CT688_RS02945	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CT688_RS02960	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CT688_RS02960	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CT688_RS02985	COG1121	(ABC) transporter
CT688_RS02995	COG1877	trehalose-phosphatase activity
CT688_RS03000	COG0154	amidase activity
CT688_RS03005	COG1802	Transcriptional regulator
CT688_RS03010	COG2197	response regulator
CT688_RS03025	COG0247	lactate metabolic process
CT688_RS03025	COG0277	FAD linked oxidase domain protein
CT688_RS03030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CT688_RS03040	COG5285	phytanoyl-CoA dioxygenase
CT688_RS03045	COG0583	DNA-binding transcription factor activity
CT688_RS03050	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CT688_RS03055	COG1309	transcriptional regulator
CT688_RS03060	COG1960	acyl-CoA dehydrogenase activity
CT688_RS03065	COG1960	acyl-CoA dehydrogenase activity
CT688_RS03070	COG2030	dehydratase
CT688_RS03080	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CT688_RS03085	COG0657	acetylesterase activity
CT688_RS03100	COG0366	Alpha amylase catalytic
CT688_RS03115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CT688_RS03120	COG2030	dehydratase
CT688_RS03125	COG1053	succinate dehydrogenase
CT688_RS03130	COG3971	2-oxopent-4-enoate hydratase activity
CT688_RS03135	COG1414	Transcriptional regulator
CT688_RS03140	COG1403	HNH endonuclease
CT688_RS03145	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CT688_RS03150	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CT688_RS03165	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CT688_RS03180	COG1960	acyl-CoA dehydrogenase activity
CT688_RS03185	COG0346	lactoylglutathione lyase activity
CT688_RS03190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CT688_RS03205	COG1218	3'(2'),5'-bisphosphate nucleotidase
CT688_RS03210	COG1960	acyl-CoA dehydrogenase activity
CT688_RS03215	COG1960	acyl-CoA dehydrogenase activity
CT688_RS03220	COG1960	acyl-CoA dehydrogenase activity
CT688_RS03225	COG1024	Enoyl-CoA hydratase
CT688_RS03230	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS03235	COG0318	PFAM AMP-dependent synthetase and ligase
CT688_RS03240	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS03245	COG1960	acyl-CoA dehydrogenase activity
CT688_RS03250	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS03260	COG1309	transcriptional regulator
CT688_RS03265	COG0183	Belongs to the thiolase family
CT688_RS03290	COG1024	Enoyl-CoA hydratase
CT688_RS03295	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS03300	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS03320	COG0183	Belongs to the thiolase family
CT688_RS03325	COG2124	cytochrome p450
CT688_RS03330	COG2267	carboxylic ester hydrolase activity
CT688_RS03365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CT688_RS03380	COG1012	belongs to the aldehyde dehydrogenase family
CT688_RS03385	COG1024	Enoyl-CoA hydratase
CT688_RS03395	COG2070	2-Nitropropane dioxygenase
CT688_RS03400	COG1272	protein, Hemolysin III
CT688_RS03405	COG0318	PFAM AMP-dependent synthetase and ligase
CT688_RS03410	COG1960	acyl-CoA dehydrogenase activity
CT688_RS03415	COG1960	acyl-CoA dehydrogenase activity
CT688_RS03430	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CT688_RS03435	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CT688_RS03460	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CT688_RS03480	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CT688_RS03510	COG0537	adenosine 5'-monophosphoramidase activity
CT688_RS03525	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CT688_RS03530	COG1960	acyl-CoA dehydrogenase activity
CT688_RS03535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CT688_RS03545	COG0471	metal ion transport
CT688_RS03550	COG0436	Aminotransferase
CT688_RS03555	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CT688_RS03560	COG2197	response regulator
CT688_RS03575	COG2267	carboxylic ester hydrolase activity
CT688_RS03580	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CT688_RS03600	COG0386	Belongs to the glutathione peroxidase family
CT688_RS03610	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CT688_RS03615	COG0047	phosphoribosylformylglycinamidine synthase activity
CT688_RS03625	COG3268	Saccharopine dehydrogenase
CT688_RS03660	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CT688_RS03680	COG1271	oxidase subunit
CT688_RS03685	COG1294	oxidase, subunit
CT688_RS03690	COG4988	ABC transporter
CT688_RS03695	COG1132	(ABC) transporter
CT688_RS03700	COG4044	May play a role in the intracellular transport of hydrophobic ligands
CT688_RS03720	COG0745	RESPONSE REGULATOR receiver
CT688_RS03725	COG0454	-acetyltransferase
CT688_RS03725	COG0456	acetyltransferase
CT688_RS03745	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CT688_RS03790	COG0523	cobalamin synthesis protein
CT688_RS03795	COG2197	response regulator
CT688_RS03805	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CT688_RS03825	COG2826	transposase and inactivated derivatives, IS30 family
CT688_RS03835	COG0183	Belongs to the thiolase family
CT688_RS03840	COG1250	3-hydroxyacyl-CoA dehydrogenase
CT688_RS03840	COG1024	Enoyl-CoA hydratase
CT688_RS03850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CT688_RS03855	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CT688_RS03880	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CT688_RS03890	COG2223	nitrite transmembrane transporter activity
CT688_RS03895	COG0243	molybdopterin cofactor binding
CT688_RS03900	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CT688_RS03915	COG2146	nitrite reductase [NAD(P)H] activity
CT688_RS03915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CT688_RS03925	COG1061	Type III restriction enzyme res subunit
CT688_RS03940	COG1652	LysM domain
CT688_RS03950	COG1278	Cold shock
CT688_RS03960	COG2814	Major facilitator Superfamily
CT688_RS03980	COG2252	PERMEase
CT688_RS04015	COG0545	Peptidyl-prolyl cis-trans isomerase
CT688_RS04040	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CT688_RS04070	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CT688_RS04080	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CT688_RS04090	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CT688_RS04105	COG1214	PFAM Peptidase M22, glycoprotease
CT688_RS04105	COG0456	acetyltransferase
CT688_RS04110	COG1214	PFAM Peptidase M22, glycoprotease
CT688_RS04110	COG0456	acetyltransferase
CT688_RS04115	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CT688_RS04125	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CT688_RS04130	COG0459	protein refolding
CT688_RS04220	COG0587	DNA-directed DNA polymerase activity
CT688_RS04240	COG2409	Drug exporters of the RND superfamily
CT688_RS04245	COG0277	FAD linked oxidase domain protein
CT688_RS04255	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CT688_RS04260	COG1121	(ABC) transporter
CT688_RS04270	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CT688_RS04275	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CT688_RS04295	COG2873	o-acetylhomoserine
CT688_RS04300	COG0385	Bile acid
CT688_RS04310	COG2814	Major facilitator Superfamily
CT688_RS04325	COG0180	Tryptophanyl-tRNA synthetase
CT688_RS04330	COG0328	RNA-DNA hybrid ribonuclease activity
CT688_RS04345	COG1017	nitric oxide dioxygenase activity
CT688_RS04345	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CT688_RS04355	COG1686	Belongs to the peptidase S11 family
CT688_RS04360	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CT688_RS04375	COG2009	succinate dehydrogenase
CT688_RS04405	COG0791	NLP P60 protein
CT688_RS04450	COG3842	ATPase activity
CT688_RS04455	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CT688_RS04460	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CT688_RS04465	COG4770	biotin carboxylase activity
CT688_RS04470	COG0424	maF-like protein
CT688_RS04480	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CT688_RS04500	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CT688_RS04505	COG1960	acyl-CoA dehydrogenase activity
CT688_RS04515	COG1316	TRANSCRIPTIONal
CT688_RS04525	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CT688_RS04530	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CT688_RS04530	COG0778	Nitroreductase
CT688_RS04535	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CT688_RS04555	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CT688_RS04565	COG1482	cell wall glycoprotein biosynthetic process
CT688_RS04580	COG0745	RESPONSE REGULATOR receiver
CT688_RS04585	COG5002	protein histidine kinase activity
CT688_RS04600	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CT688_RS04605	COG0653	protein targeting
CT688_RS04635	COG1162	GTPase activity
CT688_RS04640	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CT688_RS04665	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CT688_RS04685	COG0513	Belongs to the DEAD box helicase family
CT688_RS04695	COG1309	transcriptional regulator
CT688_RS04725	COG0210	DNA helicase
CT688_RS04750	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CT688_RS04770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CT688_RS04775	COG1615	UPF0182 protein
CT688_RS04785	COG1024	Enoyl-CoA hydratase
CT688_RS04790	COG1309	transcriptional regulator
CT688_RS04800	COG1024	Enoyl-CoA hydratase
CT688_RS04810	COG1960	acyl-CoA dehydrogenase activity
CT688_RS04815	COG1309	transcriptional regulator
CT688_RS04835	COG1960	acyl-CoA dehydrogenase activity
CT688_RS04845	COG0483	inositol monophosphate 1-phosphatase activity
CT688_RS04850	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CT688_RS04855	COG0668	transmembrane transport
CT688_RS04865	COG2884	Cell division ATP-binding protein ftsE
CT688_RS04870	COG2177	Part of the ABC transporter FtsEX involved in
CT688_RS04905	COG3304	Inner membrane component domain
CT688_RS04910	COG2723	6-phospho-beta-galactosidase activity
CT688_RS04920	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CT688_RS04935	COG1780	Probably involved in ribonucleotide reductase function
CT688_RS04940	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CT688_RS04965	COG1484	DNA-dependent DNA replication
CT688_RS05005	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CT688_RS05025	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CT688_RS05030	COG1234	tRNA 3'-trailer cleavage
CT688_RS05035	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CT688_RS05075	COG3265	gluconokinase activity
CT688_RS05090	COG0733	neurotransmitter:sodium symporter activity
CT688_RS05100	COG2030	dehydratase
CT688_RS05105	COG0736	holo-[acyl-carrier-protein] synthase activity
CT688_RS05130	COG1376	ErfK ybiS ycfS ynhG family protein
CT688_RS05150	COG4171	peptide transport system, permease
CT688_RS05160	COG4166	transmembrane transport
CT688_RS05165	COG0492	ferredoxin-NADP+ reductase activity
CT688_RS05170	COG3433	isochorismatase activity
CT688_RS05170	COG2226	methyltransferase
CT688_RS05170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CT688_RS05185	COG1132	(ABC) transporter
CT688_RS05190	COG1132	(ABC) transporter
CT688_RS05280	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CT688_RS05285	COG0300	oxidoreductase activity
CT688_RS05295	COG0546	phosphoglycolate phosphatase activity
CT688_RS05300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CT688_RS05305	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CT688_RS05315	COG1116	anion transmembrane transporter activity
CT688_RS05365	COG0366	Alpha amylase catalytic
CT688_RS05380	COG1968	undecaprenyl-diphosphatase activity
CT688_RS05390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CT688_RS05395	COG1120	ATPase activity
CT688_RS05425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CT688_RS05435	COG0318	PFAM AMP-dependent synthetase and ligase
CT688_RS05440	COG0179	Fumarylacetoacetate (FAA) hydrolase
CT688_RS05460	COG2124	cytochrome p450
CT688_RS05475	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CT688_RS05500	COG0544	peptidyl-prolyl cis-trans isomerase activity
CT688_RS05505	COG0740	serine-type endopeptidase activity
CT688_RS05510	COG0740	serine-type endopeptidase activity
CT688_RS05515	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CT688_RS05525	COG0596	Alpha beta hydrolase
CT688_RS05530	COG0039	L-malate dehydrogenase activity
CT688_RS05535	COG0525	valine-tRNA ligase activity
CT688_RS05540	COG0285	dihydrofolate synthase activity
CT688_RS05550	COG0105	UTP biosynthetic process
CT688_RS05555	COG1530	ribonuclease E activity
CT688_RS05570	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CT688_RS05575	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CT688_RS05600	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CT688_RS05605	COG2072	flavoprotein involved in K transport
CT688_RS05610	COG0318	PFAM AMP-dependent synthetase and ligase
CT688_RS05625	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CT688_RS05630	COG0569	domain protein
CT688_RS05640	COG0514	ATP-dependent DNA helicase (RecQ)
CT688_RS05645	COG4106	trans-aconitate 2-methyltransferase activity
CT688_RS05650	COG0076	glutamate decarboxylase activity
CT688_RS05660	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CT688_RS05665	COG0542	response to heat
CT688_RS05675	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CT688_RS05680	COG0799	negative regulation of ribosome biogenesis
CT688_RS05690	COG1307	EDD domain protein, DegV family
CT688_RS05705	COG0300	oxidoreductase activity
CT688_RS05715	COG0268	Binds directly to 16S ribosomal RNA
CT688_RS05730	COG0481	GTPase activity
CT688_RS05745	COG0339	signal peptide processing
CT688_RS05765	COG1420	regulation of RNA biosynthetic process
CT688_RS05770	COG0484	heat shock protein binding
CT688_RS05805	COG1381	Involved in DNA repair and RecF pathway recombination
CT688_RS05810	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CT688_RS05825	COG0423	glycine-tRNA ligase activity
CT688_RS05835	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CT688_RS05850	COG0358	DNA primase activity
CT688_RS05875	COG1476	TRANSCRIPTIONal
CT688_RS05890	COG0582	viral genome integration into host DNA
CT688_RS05955	COG0464	growth
CT688_RS05970	COG0657	acetylesterase activity
CT688_RS05975	COG1131	(ABC) transporter
CT688_RS06000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CT688_RS06015	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CT688_RS06040	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CT688_RS06065	COG3323	Protein of unknown function (DUF1653)
CT688_RS06065	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CT688_RS06090	COG2072	flavoprotein involved in K transport
CT688_RS06105	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CT688_RS06110	COG0174	glutamine synthetase
CT688_RS06115	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CT688_RS06150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CT688_RS06160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CT688_RS06170	COG0174	glutamine synthetase
CT688_RS06185	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CT688_RS06190	COG0321	lipoyl(octanoyl) transferase activity
CT688_RS06195	COG0508	dehydrogenase complex catalyzes the overall conversion of
CT688_RS06205	COG0252	asparaginase activity
CT688_RS06220	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CT688_RS06230	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CT688_RS06245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CT688_RS06255	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CT688_RS06280	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CT688_RS06295	COG1845	cytochrome c oxidase, subunit III
CT688_RS06300	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CT688_RS06315	COG0791	NLP P60 protein
CT688_RS06325	COG0438	transferase activity, transferring glycosyl groups
CT688_RS06355	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CT688_RS06375	COG0142	geranyltranstransferase activity
CT688_RS06425	COG0768	penicillin binding
CT688_RS06445	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CT688_RS06455	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CT688_RS06460	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CT688_RS06465	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CT688_RS06470	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CT688_RS06480	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CT688_RS06495	COG3599	regulation of cell shape
CT688_RS06505	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CT688_RS06515	COG0252	asparaginase activity
CT688_RS06530	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CT688_RS06565	COG1739	Uncharacterized protein family UPF0029
CT688_RS06575	COG0778	Nitroreductase
CT688_RS06635	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CT688_RS06670	COG2315	Protein conserved in bacteria
CT688_RS06680	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CT688_RS06685	COG0076	glutamate decarboxylase activity
CT688_RS06695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CT688_RS06700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CT688_RS06705	COG1120	ATPase activity
CT688_RS06745	COG1122	ATPase activity
CT688_RS06750	COG1268	BioY protein
CT688_RS06765	COG0577	efflux transmembrane transporter activity
CT688_RS06765	COG1136	(ABC) transporter
CT688_RS06770	COG0577	efflux transmembrane transporter activity
CT688_RS06795	COG2197	response regulator
CT688_RS06800	COG3850	Histidine kinase
CT688_RS06810	COG1136	(ABC) transporter
CT688_RS06815	COG0640	Transcriptional regulator
CT688_RS06825	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CT688_RS06835	COG0131	Imidazoleglycerol-phosphate dehydratase
CT688_RS06845	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CT688_RS06855	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CT688_RS06860	COG0483	inositol monophosphate 1-phosphatase activity
CT688_RS06865	COG0107	imidazoleglycerol-phosphate synthase activity
CT688_RS06870	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CT688_RS06880	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CT688_RS06905	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CT688_RS06910	COG0469	pyruvate kinase activity
CT688_RS06930	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CT688_RS06950	COG1802	Transcriptional regulator
CT688_RS06965	COG1335	isochorismatase
CT688_RS06985	COG1129	ABC transporter
CT688_RS07000	COG1012	belongs to the aldehyde dehydrogenase family
CT688_RS07005	COG1902	pentaerythritol trinitrate reductase activity
CT688_RS07010	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS07015	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS07045	COG1484	DNA-dependent DNA replication
CT688_RS07080	COG1484	DNA-dependent DNA replication
CT688_RS07110	COG0765	amino acid transport
CT688_RS07115	COG1126	abc transporter atp-binding protein
CT688_RS07130	COG0237	dephospho-CoA kinase activity
CT688_RS07130	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CT688_RS07160	COG3973	AAA domain
CT688_RS07190	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CT688_RS07200	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CT688_RS07205	COG0488	(ABC) transporter
CT688_RS07210	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CT688_RS07215	COG0072	phenylalanine-tRNA ligase activity
CT688_RS07215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CT688_RS07220	COG0352	thiamine-phosphate diphosphorylase activity
CT688_RS07220	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CT688_RS07220	COG0351	phosphomethylpyrimidine kinase
CT688_RS07230	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CT688_RS07240	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CT688_RS07250	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CT688_RS07255	COG1438	arginine binding
CT688_RS07265	COG0165	Argininosuccinate lyase
CT688_RS07275	COG2094	Belongs to the DNA glycosylase MPG family
CT688_RS07280	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CT688_RS07305	COG0647	UMP catabolic process
CT688_RS07320	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CT688_RS07345	COG0494	nUDIX hydrolase
CT688_RS07360	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CT688_RS07365	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CT688_RS07375	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CT688_RS07380	COG1160	GTP binding
CT688_RS07415	COG2130	NADP-dependent
CT688_RS07440	COG1716	ATPase activity
CT688_RS07460	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CT688_RS07460	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CT688_RS07470	COG0596	Alpha beta hydrolase
CT688_RS07475	COG0318	PFAM AMP-dependent synthetase and ligase
CT688_RS07485	COG3012	SEC-C Motif Domain Protein
CT688_RS07530	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CT688_RS07540	COG0123	including yeast histone deacetylase and acetoin utilization protein
CT688_RS07545	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CT688_RS07545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CT688_RS07590	COG0483	inositol monophosphate 1-phosphatase activity
CT688_RS07610	COG0756	dUTP diphosphatase activity
CT688_RS07640	COG0450	alkyl hydroperoxide reductase
CT688_RS07655	COG0513	Belongs to the DEAD box helicase family
CT688_RS07660	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CT688_RS07675	COG1252	NADH dehydrogenase
CT688_RS07680	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CT688_RS07715	COG0596	Alpha beta hydrolase
CT688_RS07715	COG0508	dehydrogenase complex catalyzes the overall conversion of
CT688_RS07750	COG1846	Transcriptional regulator
CT688_RS07795	COG0463	Glycosyl transferase, family 2
CT688_RS07820	COG0300	oxidoreductase activity
CT688_RS07835	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CT688_RS07865	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CT688_RS07880	COG1222	aaa ATPase
CT688_RS07900	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CT688_RS07905	COG0140	phosphoribosyl-ATP diphosphatase activity
CT688_RS07935	COG0215	cysteine-tRNA ligase activity
CT688_RS07955	COG1968	undecaprenyl-diphosphatase activity
CT688_RS08015	COG4941	Belongs to the sigma-70 factor family
CT688_RS08055	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CT688_RS08065	COG2304	oxidoreductase activity
CT688_RS08075	COG0714	Associated with various cellular activities
CT688_RS08080	COG0791	NLP P60 protein
CT688_RS08080	COG3883	PFAM NLP P60 protein
CT688_RS08090	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CT688_RS08095	COG1309	transcriptional regulator
CT688_RS08140	COG0488	(ABC) transporter
CT688_RS08160	COG2151	metal-sulfur cluster biosynthetic enzyme
CT688_RS08165	COG0822	iron-sulfur transferase activity
CT688_RS08175	COG0396	ATPase activity
CT688_RS08180	COG0719	Fe-S assembly protein
CT688_RS08200	COG1131	(ABC) transporter
CT688_RS08230	COG0109	protoheme IX farnesyltransferase activity
CT688_RS08235	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CT688_RS08240	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CT688_RS08255	COG0363	glucosamine-6-phosphate deaminase activity
CT688_RS08260	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CT688_RS08265	COG0149	triose-phosphate isomerase activity
CT688_RS08270	COG0126	phosphoglycerate kinase activity
CT688_RS08275	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CT688_RS08280	COG1481	regulation of sporulation
CT688_RS08295	COG0322	excinuclease ABC activity
CT688_RS08310	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CT688_RS08310	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CT688_RS08340	COG0242	peptide deformylase activity
CT688_RS08350	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CT688_RS08360	COG1758	RNA polymerase activity
CT688_RS08365	COG0194	GDP metabolic process
CT688_RS08375	COG0284	orotidine-5'-phosphate decarboxylase activity
CT688_RS08380	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CT688_RS08410	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CT688_RS08415	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CT688_RS08420	COG0006	proline dipeptidase activity
CT688_RS08425	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CT688_RS08430	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CT688_RS08445	COG2072	flavoprotein involved in K transport
CT688_RS08450	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CT688_RS08455	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CT688_RS08465	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CT688_RS08490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CT688_RS08495	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CT688_RS08500	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CT688_RS08510	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CT688_RS08515	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CT688_RS08525	COG2255	four-way junction helicase activity
CT688_RS08530	COG0632	four-way junction helicase activity
CT688_RS08535	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CT688_RS08540	COG0217	transcriptional regulatory protein
CT688_RS08545	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CT688_RS08550	COG1946	Acyl-CoA thioesterase
CT688_RS08555	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CT688_RS08565	COG0438	transferase activity, transferring glycosyl groups
CT688_RS08575	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CT688_RS08585	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CT688_RS08590	COG0785	Cytochrome C biogenesis protein
CT688_RS08605	COG2132	Multicopper oxidase
CT688_RS08675	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CT688_RS08690	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CT688_RS08705	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CT688_RS08710	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CT688_RS08715	COG0531	amino acid
CT688_RS08720	COG0569	domain protein
CT688_RS08740	COG1643	Atp-dependent helicase
CT688_RS08750	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CT688_RS08765	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CT688_RS08770	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CT688_RS08775	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CT688_RS08780	COG1414	Transcriptional regulator
CT688_RS08785	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CT688_RS08795	COG1196	nuclear chromosome segregation
CT688_RS08805	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CT688_RS08810	COG2137	regulation of response to DNA damage stimulus
CT688_RS08815	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CT688_RS08825	COG1842	Phage shock protein A
CT688_RS08830	COG1396	sequence-specific DNA binding
CT688_RS08835	COG1546	Belongs to the CinA family
CT688_RS08835	COG1058	Belongs to the CinA family
CT688_RS08865	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CT688_RS08870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CT688_RS08890	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CT688_RS08905	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CT688_RS08915	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CT688_RS08930	COG0534	Mate efflux family protein
CT688_RS08935	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CT688_RS08940	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CT688_RS08945	COG0481	GTPase activity
CT688_RS08945	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CT688_RS08975	COG0442	prolyl-tRNA aminoacylation
CT688_RS08980	COG3022	response to hydroperoxide
CT688_RS08990	COG0579	oxidoreductase
CT688_RS09015	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CT688_RS09020	COG0750	zinc metalloprotease
CT688_RS09025	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CT688_RS09060	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CT688_RS09065	COG0052	Belongs to the universal ribosomal protein uS2 family
CT688_RS09080	COG2186	Transcriptional regulator
CT688_RS09090	COG0318	PFAM AMP-dependent synthetase and ligase
CT688_RS09115	COG0792	nuclease activity
CT688_RS09125	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CT688_RS09130	COG0681	Belongs to the peptidase S26 family
CT688_RS09135	COG0335	large ribosomal subunit rRNA binding
CT688_RS09140	COG0336	Belongs to the RNA methyltransferase TrmD family
CT688_RS09145	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CT688_RS09155	COG0228	four-way junction DNA binding
CT688_RS09165	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CT688_RS09190	COG1053	succinate dehydrogenase
CT688_RS09195	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CT688_RS09200	COG1196	nuclear chromosome segregation
CT688_RS09210	COG1254	Belongs to the acylphosphatase family
CT688_RS09220	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CT688_RS09225	COG0571	ribonuclease III activity
CT688_RS09240	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CT688_RS09245	COG0742	ribosomal rna small subunit methyltransferase
CT688_RS09250	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CT688_RS09260	COG1024	Enoyl-CoA hydratase
CT688_RS09270	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CT688_RS09285	COG1181	Belongs to the D-alanine--D-alanine ligase family
CT688_RS09290	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CT688_RS09295	COG1920	GTP binding
CT688_RS09300	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CT688_RS09305	COG0494	nUDIX hydrolase
CT688_RS09305	COG0406	alpha-ribazole phosphatase activity
CT688_RS09315	COG0066	3-isopropylmalate dehydratase activity
CT688_RS09320	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CT688_RS09340	COG1309	transcriptional regulator
CT688_RS09365	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CT688_RS09375	COG0179	Fumarylacetoacetate (FAA) hydrolase
CT688_RS09390	COG0473	3-isopropylmalate dehydrogenase activity
CT688_RS09405	COG1233	COG1233 Phytoene dehydrogenase and related
CT688_RS09415	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CT688_RS09420	COG0440	acetolactate synthase activity
CT688_RS09440	COG0129	dihydroxy-acid dehydratase activity
CT688_RS09445	COG2259	Doxx family
CT688_RS09455	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CT688_RS09460	COG0205	6-phosphofructokinase activity
CT688_RS09470	COG0154	amidase activity
CT688_RS09475	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CT688_RS09485	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CT688_RS09510	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CT688_RS09520	COG0318	PFAM AMP-dependent synthetase and ligase
CT688_RS09540	COG1119	ATPase activity
CT688_RS09545	COG0366	Alpha amylase catalytic
CT688_RS09560	COG0183	Belongs to the thiolase family
CT688_RS09580	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CT688_RS09600	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CT688_RS09605	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CT688_RS09615	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CT688_RS09620	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CT688_RS09625	COG0356	it plays a direct role in the translocation of protons across the membrane
CT688_RS09645	COG2890	protein-(glutamine-N5) methyltransferase activity
CT688_RS09650	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CT688_RS09660	COG0318	PFAM AMP-dependent synthetase and ligase
CT688_RS09665	COG0083	homoserine kinase activity
CT688_RS09670	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CT688_RS09675	COG0460	homoserine dehydrogenase
CT688_RS09685	COG0018	arginyl-trna synthetase
CT688_RS09705	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CT688_RS09715	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CT688_RS09730	COG0477	Major facilitator Superfamily
CT688_RS09735	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CT688_RS09760	COG0567	Dehydrogenase, E1 component
CT688_RS09760	COG0508	dehydrogenase complex catalyzes the overall conversion of
CT688_RS09770	COG0598	Magnesium transport protein CorA
CT688_RS09785	COG2301	Belongs to the HpcH HpaI aldolase family
CT688_RS09815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CT688_RS09820	COG5662	AntiSigma factor
CT688_RS09835	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CT688_RS09840	COG0297	glycogen (starch) synthase activity
CT688_RS09845	COG2226	methyltransferase
CT688_RS09850	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CT688_RS09865	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CT688_RS09870	COG1611	Belongs to the LOG family
CT688_RS09880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CT688_RS09900	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CT688_RS09920	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CT688_RS09925	COG0747	negative chemotaxis
CT688_RS09930	COG1217	gtp-binding protein TYPA
CT688_RS09940	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CT688_RS09955	COG0427	acetyl-CoA hydrolase
CT688_RS09960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CT688_RS09965	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CT688_RS09970	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CT688_RS09970	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CT688_RS09990	COG2354	Protein conserved in bacteria
CT688_RS09995	COG4044	May play a role in the intracellular transport of hydrophobic ligands
CT688_RS10015	COG0129	dihydroxy-acid dehydratase activity
CT688_RS10090	COG3360	Dodecin
CT688_RS10120	COG0012	GTP binding
CT688_RS10135	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CT688_RS10145	COG1570	exodeoxyribonuclease VII activity
CT688_RS10160	COG1494	fructose-1,6-bisphosphatase
CT688_RS10170	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CT688_RS10190	COG2188	Transcriptional regulator
CT688_RS10205	COG1960	acyl-CoA dehydrogenase activity
CT688_RS10210	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CT688_RS10220	COG0183	Belongs to the thiolase family
CT688_RS10225	COG1960	acyl-CoA dehydrogenase activity
CT688_RS10230	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS10240	COG0477	Major facilitator Superfamily
CT688_RS10245	COG0318	PFAM AMP-dependent synthetase and ligase
CT688_RS10285	COG1021	2,3-dihydroxybenzoate-AMP ligase
CT688_RS10295	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS10305	COG1960	acyl-CoA dehydrogenase activity
CT688_RS10315	COG1960	acyl-CoA dehydrogenase activity
CT688_RS10320	COG0183	Belongs to the thiolase family
CT688_RS10330	COG1024	Enoyl-CoA hydratase
CT688_RS10345	COG1840	ABC-type Fe3 transport system, periplasmic component
CT688_RS10370	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS10375	COG1064	alcohol dehydrogenase
CT688_RS10380	COG0446	pyridine nucleotide-disulphide oxidoreductase
CT688_RS10380	COG1902	pentaerythritol trinitrate reductase activity
CT688_RS10400	COG1960	acyl-CoA dehydrogenase activity
CT688_RS10415	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CT688_RS10420	COG1072	(Pantothenic acid kinase))
CT688_RS10445	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CT688_RS10450	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CT688_RS10460	COG1403	HNH endonuclease
CT688_RS10470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CT688_RS10475	COG0431	NADPH-dependent FMN reductase
CT688_RS10510	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CT688_RS10525	COG1401	restriction endodeoxyribonuclease activity
CT688_RS10535	COG2755	lipolytic protein G-D-S-L family
CT688_RS10540	COG0183	Belongs to the thiolase family
CT688_RS10545	COG2826	transposase and inactivated derivatives, IS30 family
CT688_RS10565	COG1131	(ABC) transporter
CT688_RS10590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CT688_RS10595	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS10605	COG3973	AAA domain
CT688_RS10610	COG0477	Major facilitator Superfamily
CT688_RS10625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CT688_RS10630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CT688_RS10635	COG1120	ATPase activity
CT688_RS10665	COG2264	protein methyltransferase activity
CT688_RS10705	COG2801	Transposase and inactivated derivatives
CT688_RS10720	COG1484	DNA-dependent DNA replication
CT688_RS10740	COG4584	PFAM Integrase catalytic
CT688_RS10745	COG1484	DNA-dependent DNA replication
CT688_RS10780	COG2801	Transposase and inactivated derivatives
CT688_RS10830	COG0148	phosphopyruvate hydratase activity
CT688_RS10850	COG0531	amino acid
CT688_RS10855	COG2239	Acts as a magnesium transporter
CT688_RS10860	COG0596	Alpha beta hydrolase
CT688_RS10900	COG1132	(ABC) transporter
CT688_RS10905	COG1132	(ABC) transporter
CT688_RS10935	COG1304	FMN binding
CT688_RS10945	COG3956	TIGRFAM MazG family protein
CT688_RS10960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CT688_RS10970	COG2072	flavoprotein involved in K transport
CT688_RS10980	COG2144	transferase activity, transferring acyl groups
CT688_RS11010	COG1309	transcriptional regulator
CT688_RS11040	COG0028	Belongs to the TPP enzyme family
CT688_RS11045	COG0655	NAD(P)H dehydrogenase (quinone) activity
CT688_RS11065	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CT688_RS11080	COG0193	aminoacyl-tRNA hydrolase activity
CT688_RS11090	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CT688_RS11105	COG2723	6-phospho-beta-galactosidase activity
CT688_RS11115	COG0628	permease
CT688_RS11125	COG2326	polyphosphate kinase activity
CT688_RS11150	COG0488	(ABC) transporter
CT688_RS11155	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CT688_RS11160	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CT688_RS11170	COG0084	hydrolase, TatD family'
CT688_RS11175	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CT688_RS11180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CT688_RS11185	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CT688_RS11225	COG2271	Major facilitator Superfamily
CT688_RS11250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CT688_RS11260	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CT688_RS11265	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CT688_RS11280	COG1970	mechanosensitive ion channel activity
CT688_RS11290	COG0521	Mo-molybdopterin cofactor biosynthetic process
CT688_RS11290	COG0315	cyclic pyranopterin monophosphate synthase activity
CT688_RS11295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CT688_RS11300	COG2205	protein histidine kinase activity
CT688_RS11315	COG0254	rRNA binding
CT688_RS11320	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CT688_RS11325	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CT688_RS11330	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CT688_RS11335	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CT688_RS11360	COG0318	PFAM AMP-dependent synthetase and ligase
CT688_RS11370	COG2030	dehydratase
CT688_RS11375	COG1960	acyl-CoA dehydrogenase activity
CT688_RS11385	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CT688_RS11455	COG1115	amino acid carrier protein
CT688_RS11470	COG0166	Belongs to the GPI family
CT688_RS11490	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CT688_RS11500	COG1201	RNA secondary structure unwinding
CT688_RS11530	COG1937	Protein conserved in bacteria
CT688_RS11540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CT688_RS11565	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS11580	COG0535	radical SAM domain protein
CT688_RS11620	COG1120	ATPase activity
CT688_RS11625	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CT688_RS11630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CT688_RS11650	COG1012	belongs to the aldehyde dehydrogenase family
CT688_RS11675	COG1674	ftsk spoiiie
CT688_RS11685	COG1404	Belongs to the peptidase S8 family
CT688_RS11705	COG0702	epimerase
CT688_RS11715	COG0101	tRNA pseudouridine synthase activity
CT688_RS11730	COG2755	lipolytic protein G-D-S-L family
CT688_RS11735	COG0203	ribosomal protein L17
CT688_RS11740	COG0202	RNA polymerase activity
CT688_RS11750	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CT688_RS11755	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CT688_RS11760	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CT688_RS11775	COG0563	adenylate kinase activity
CT688_RS11780	COG0201	protein transport
CT688_RS11785	COG0200	Binds to the 23S rRNA
CT688_RS11790	COG1841	ribosomal large subunit assembly
CT688_RS11800	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CT688_RS11815	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CT688_RS11820	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CT688_RS11825	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CT688_RS11835	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CT688_RS11840	COG0255	Belongs to the universal ribosomal protein uL29 family
CT688_RS11855	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CT688_RS11860	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CT688_RS11875	COG0088	Forms part of the polypeptide exit tunnel
CT688_RS11885	COG0051	transcription antitermination factor activity, RNA binding
CT688_RS11900	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CT688_RS11910	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CT688_RS11940	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CT688_RS11945	COG1960	acyl-CoA dehydrogenase activity
CT688_RS11975	COG0477	Major facilitator Superfamily
CT688_RS11980	COG2124	cytochrome p450
CT688_RS11995	COG1960	acyl-CoA dehydrogenase activity
CT688_RS12005	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CT688_RS12010	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS12035	COG2124	cytochrome p450
CT688_RS12040	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS12085	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
CT688_RS12100	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS12115	COG2226	methyltransferase
CT688_RS12120	COG0438	transferase activity, transferring glycosyl groups
CT688_RS12175	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CT688_RS12180	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CT688_RS12190	COG0222	ribosome binding
CT688_RS12195	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CT688_RS12205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CT688_RS12210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CT688_RS12215	COG0081	regulation of translation
CT688_RS12220	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CT688_RS12245	COG2030	dehydratase
CT688_RS12255	COG4565	transcriptional regulatory protein
CT688_RS12260	COG3290	protein histidine kinase activity
CT688_RS12310	COG1562	ergosterol biosynthetic process
CT688_RS12315	COG0142	geranyltranstransferase activity
CT688_RS12350	COG0142	geranyltranstransferase activity
CT688_RS12355	COG0644	oxidoreductase
CT688_RS12360	COG2226	methyltransferase
CT688_RS12365	COG0438	transferase activity, transferring glycosyl groups
CT688_RS12375	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CT688_RS12385	COG2318	DinB family
CT688_RS12405	COG4948	Mandelate Racemase Muconate Lactonizing
CT688_RS12445	COG4181	ATPase activity
CT688_RS12450	COG0577	efflux transmembrane transporter activity
CT688_RS12465	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CT688_RS12475	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CT688_RS12505	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CT688_RS12510	COG1088	dTDP-glucose 4,6-dehydratase activity
CT688_RS12520	COG1295	ribonuclease BN
CT688_RS12530	COG1218	3'(2'),5'-bisphosphate nucleotidase
CT688_RS12540	COG0730	response to heat
CT688_RS12545	COG0730	response to heat
CT688_RS12555	COG0175	sulfate reduction
CT688_RS12570	COG1012	belongs to the aldehyde dehydrogenase family
CT688_RS12585	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS12595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CT688_RS12600	COG0235	Class ii aldolase
CT688_RS12615	COG0657	acetylesterase activity
CT688_RS12685	COG0559	Belongs to the binding-protein-dependent transport system permease family
CT688_RS12695	COG0829	nickel cation binding
CT688_RS12700	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CT688_RS12705	COG0830	nickel cation binding
CT688_RS12710	COG0804	urea catabolic process
CT688_RS12720	COG0831	urea catabolic process
CT688_RS12730	COG2351	hydroxyisourate hydrolase activity
CT688_RS12755	COG0402	S-adenosylhomocysteine deaminase activity
CT688_RS12790	COG0402	S-adenosylhomocysteine deaminase activity
CT688_RS12815	COG2072	flavoprotein involved in K transport
CT688_RS12820	COG4266	Belongs to the allantoicase family
CT688_RS12825	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CT688_RS12865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CT688_RS12875	COG1309	transcriptional regulator
CT688_RS12885	COG2205	protein histidine kinase activity
CT688_RS12890	COG0745	RESPONSE REGULATOR receiver
CT688_RS12950	COG1595	DNA-templated transcription, initiation
CT688_RS13020	COG2267	carboxylic ester hydrolase activity
CT688_RS13090	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CT688_RS13100	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CT688_RS13125	COG1309	transcriptional regulator
CT688_RS13140	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS13150	COG0183	Belongs to the thiolase family
CT688_RS13180	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS13195	COG0783	Belongs to the Dps family
CT688_RS13205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CT688_RS13210	COG0586	Pfam SNARE associated Golgi protein
CT688_RS13240	COG1764	response to oxidative stress
CT688_RS13255	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CT688_RS13260	COG1086	Polysaccharide biosynthesis protein
CT688_RS13270	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CT688_RS13305	COG1086	Polysaccharide biosynthesis protein
CT688_RS13310	COG0489	protein tyrosine kinase activity
CT688_RS13320	COG1960	acyl-CoA dehydrogenase activity
CT688_RS13325	COG1960	acyl-CoA dehydrogenase activity
CT688_RS13330	COG1024	Enoyl-CoA hydratase
CT688_RS13345	COG2186	Transcriptional regulator
CT688_RS13350	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CT688_RS13370	COG2851	Citrate transporter
CT688_RS13385	COG2197	response regulator
CT688_RS13400	COG3285	dna ligase
CT688_RS13400	COG1793	dna ligase
CT688_RS13430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CT688_RS13435	COG1024	Enoyl-CoA hydratase
CT688_RS13490	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CT688_RS13495	COG1333	cytochrome c biogenesis protein
CT688_RS13565	COG0785	Cytochrome C biogenesis protein
CT688_RS13575	COG0406	alpha-ribazole phosphatase activity
CT688_RS13610	COG1648	precorrin-2 dehydrogenase activity
CT688_RS13610	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CT688_RS13615	COG0181	hydroxymethylbilane synthase activity
CT688_RS13620	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CT688_RS13680	COG0745	RESPONSE REGULATOR receiver
CT688_RS13685	COG5002	protein histidine kinase activity
CT688_RS13690	COG0588	phosphoglycerate mutase activity
CT688_RS13695	COG0318	PFAM AMP-dependent synthetase and ligase
CT688_RS13720	COG0438	transferase activity, transferring glycosyl groups
CT688_RS13740	COG1366	Belongs to the anti-sigma-factor antagonist family
CT688_RS13745	COG1215	transferase activity, transferring glycosyl groups
CT688_RS13765	COG1528	Iron-storage protein
CT688_RS13780	COG0488	(ABC) transporter
CT688_RS13785	COG0706	membrane insertase activity
CT688_RS13790	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CT688_RS13815	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CT688_RS13825	COG0789	Transcriptional regulator
CT688_RS13845	COG2733	membrane
CT688_RS13855	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CT688_RS13865	COG2224	Isocitrate lyase
CT688_RS13905	COG1505	serine-type exopeptidase activity
CT688_RS13915	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CT688_RS13955	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CT688_RS13955	COG2111	Na H antiporter
CT688_RS13960	COG1006	Multisubunit Na H antiporter MnhC subunit
CT688_RS13965	COG0651	ATP synthesis coupled electron transport
CT688_RS14015	COG2326	polyphosphate kinase activity
CT688_RS14020	COG1832	CoA-binding protein
CT688_RS14035	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CT688_RS14045	COG1131	(ABC) transporter
CT688_RS14055	COG2022	thiamine diphosphate biosynthetic process
CT688_RS14070	COG0352	thiamine-phosphate diphosphorylase activity
CT688_RS14090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CT688_RS14095	COG0515	serine threonine protein kinase
CT688_RS14120	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CT688_RS14125	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CT688_RS14140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CT688_RS14210	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CT688_RS14215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CT688_RS14220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CT688_RS14245	COG1984	allophanate hydrolase subunit 2
CT688_RS14255	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CT688_RS14265	COG4129	membrane
CT688_RS14290	COG0523	cobalamin synthesis protein
CT688_RS14310	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CT688_RS14350	COG0542	response to heat
CT688_RS14445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CT688_RS14450	COG0789	Transcriptional regulator
CT688_RS14455	COG0484	heat shock protein binding
CT688_RS14470	COG0443	Heat shock 70 kDa protein
CT688_RS14475	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CT688_RS14490	COG0247	lactate metabolic process
CT688_RS14490	COG2181	nitrate reductase activity
CT688_RS14515	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CT688_RS14550	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CT688_RS14550	COG0574	Belongs to the PEP-utilizing enzyme family
CT688_RS14555	COG1960	acyl-CoA dehydrogenase activity
CT688_RS14565	COG0183	Belongs to the thiolase family
CT688_RS14570	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS14575	COG2030	dehydratase
CT688_RS14580	COG2133	pyrroloquinoline quinone binding
CT688_RS14590	COG0738	Major facilitator superfamily
CT688_RS14605	COG2755	lipolytic protein G-D-S-L family
CT688_RS14610	COG2837	iron assimilation
CT688_RS14640	COG1842	Phage shock protein A
CT688_RS14650	COG1403	HNH endonuclease
CT688_RS14660	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS14695	COG0489	protein tyrosine kinase activity
CT688_RS14720	COG1136	(ABC) transporter
CT688_RS14720	COG0577	efflux transmembrane transporter activity
CT688_RS14725	COG1136	(ABC) transporter
CT688_RS14725	COG0577	efflux transmembrane transporter activity
CT688_RS14730	COG0564	pseudouridine synthase activity
CT688_RS14760	COG3764	Sortase (surface protein transpeptidase)
CT688_RS14780	COG1376	ErfK ybiS ycfS ynhG family protein
CT688_RS14785	COG1376	ErfK ybiS ycfS ynhG family protein
CT688_RS14805	COG3590	peptidase
CT688_RS14845	COG2409	Drug exporters of the RND superfamily
CT688_RS14855	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CT688_RS14885	COG2205	protein histidine kinase activity
CT688_RS14905	COG0438	transferase activity, transferring glycosyl groups
CT688_RS14930	COG4981	capsule polysaccharide biosynthetic process
CT688_RS14945	COG0318	PFAM AMP-dependent synthetase and ligase
CT688_RS14965	COG2070	2-Nitropropane dioxygenase
CT688_RS14975	COG1472	Belongs to the glycosyl hydrolase 3 family
CT688_RS14980	COG0519	Catalyzes the synthesis of GMP from XMP
CT688_RS14990	COG2860	membrane
CT688_RS15000	COG0435	Glutathione S-transferase
CT688_RS15010	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CT688_RS15030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CT688_RS15035	COG0798	PFAM Bile acid sodium symporter
CT688_RS15045	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CT688_RS15050	COG0659	secondary active sulfate transmembrane transporter activity
CT688_RS15055	COG0789	Transcriptional regulator
CT688_RS15075	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CT688_RS15100	COG0483	inositol monophosphate 1-phosphatase activity
CT688_RS15105	COG1174	glycine betaine transport
CT688_RS15115	COG1174	glycine betaine transport
CT688_RS15150	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CT688_RS15180	COG2409	Drug exporters of the RND superfamily
CT688_RS15185	COG0596	Alpha beta hydrolase
CT688_RS15205	COG0463	Glycosyl transferase, family 2
CT688_RS15210	COG2226	methyltransferase
CT688_RS15215	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CT688_RS15225	COG0477	Major facilitator Superfamily
CT688_RS15260	COG1376	ErfK ybiS ycfS ynhG family protein
CT688_RS15265	COG3191	aminopeptidase activity
CT688_RS15270	COG1253	flavin adenine dinucleotide binding
CT688_RS15275	COG1253	flavin adenine dinucleotide binding
CT688_RS15290	COG0768	penicillin binding
CT688_RS15300	COG1960	acyl-CoA dehydrogenase activity
CT688_RS15310	COG0640	Transcriptional regulator
CT688_RS15325	COG1595	DNA-templated transcription, initiation
CT688_RS15335	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CT688_RS15360	COG0710	3-dehydroquinate dehydratase activity
CT688_RS15370	COG2855	membrane
CT688_RS15400	COG2267	carboxylic ester hydrolase activity
CT688_RS15405	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CT688_RS15420	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CT688_RS15425	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CT688_RS15440	COG2205	protein histidine kinase activity
CT688_RS15445	COG4585	Histidine kinase
CT688_RS15450	COG2197	response regulator
CT688_RS15455	COG4152	abc transporter atp-binding protein
CT688_RS15465	COG0745	RESPONSE REGULATOR receiver
CT688_RS15470	COG1045	serine acetyltransferase
CT688_RS15480	COG3757	hydrolase, family 25
CT688_RS15490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CT688_RS15505	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CT688_RS15520	COG0277	FAD linked oxidase domain protein
CT688_RS15545	COG1027	Aspartate ammonia-lyase
CT688_RS15550	COG0671	phosphoesterase, PA-phosphatase related
CT688_RS15560	COG0326	Molecular chaperone. Has ATPase activity
CT688_RS15585	COG0765	amino acid transport
CT688_RS15590	COG0765	amino acid transport
CT688_RS15595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CT688_RS15600	COG1126	abc transporter atp-binding protein
CT688_RS15625	COG0693	protein deglycase activity
CT688_RS15640	COG0513	Belongs to the DEAD box helicase family
CT688_RS15655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CT688_RS15665	COG0351	phosphomethylpyrimidine kinase
CT688_RS15665	COG0352	thiamine-phosphate diphosphorylase activity
CT688_RS15665	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CT688_RS15675	COG1595	DNA-templated transcription, initiation
CT688_RS15690	COG0477	Major facilitator Superfamily
CT688_RS15740	COG2608	mercury ion transmembrane transporter activity
CT688_RS15745	COG1937	Protein conserved in bacteria
CT688_RS15805	COG1960	acyl-CoA dehydrogenase activity
CT688_RS15815	COG0318	PFAM AMP-dependent synthetase and ligase
CT688_RS15825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CT688_RS15830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CT688_RS15835	COG1120	ATPase activity
CT688_RS15850	COG2409	Drug exporters of the RND superfamily
CT688_RS15855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CT688_RS15870	COG2323	membrane
CT688_RS15900	COG1116	anion transmembrane transporter activity
CT688_RS15900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CT688_RS15915	COG0297	glycogen (starch) synthase activity
CT688_RS15965	COG2066	Belongs to the glutaminase family
CT688_RS15970	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CT688_RS15980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CT688_RS15995	COG0386	Belongs to the glutathione peroxidase family
CT688_RS16005	COG1652	LysM domain
CT688_RS16035	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CT688_RS16040	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CT688_RS16095	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CT688_RS16100	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CT688_RS16105	COG1349	DNA-binding transcription factor activity
CT688_RS16110	COG1105	Belongs to the carbohydrate kinase PfkB family
CT688_RS16115	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CT688_RS16115	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CT688_RS16115	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CT688_RS16125	COG0702	epimerase
CT688_RS16155	COG4303	Ethanolamine ammonia lyase large subunit
CT688_RS16160	COG0531	amino acid
CT688_RS16205	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CT688_RS16210	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CT688_RS16215	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CT688_RS16225	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CT688_RS16270	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CT688_RS16275	COG1121	(ABC) transporter
CT688_RS16285	COG3842	ATPase activity
CT688_RS16290	COG4208	sulfate ABC transporter
CT688_RS16300	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CT688_RS16325	COG3848	Pyruvate phosphate dikinase
CT688_RS16325	COG0574	Belongs to the PEP-utilizing enzyme family
CT688_RS16335	COG3002	Belongs to the UPF0753 family
CT688_RS16340	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CT688_RS16360	COG0477	Major facilitator Superfamily
CT688_RS16365	COG1472	Belongs to the glycosyl hydrolase 3 family
CT688_RS16385	COG0477	Major facilitator Superfamily
CT688_RS16395	COG1733	regulation of RNA biosynthetic process
CT688_RS16400	COG0702	epimerase
CT688_RS16405	COG2837	iron assimilation
CT688_RS16410	COG2822	iron ion transport
CT688_RS16415	COG0672	)-iron permease
CT688_RS16420	COG2226	methyltransferase
CT688_RS16450	COG2340	Cysteine-rich secretory protein family
CT688_RS16470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CT688_RS16480	COG1309	transcriptional regulator
CT688_RS16490	COG1953	Uracil, thiamine, allantoin
CT688_RS16510	COG1132	(ABC) transporter
CT688_RS16530	COG1484	DNA-dependent DNA replication
CT688_RS16610	COG0305	Participates in initiation and elongation during chromosome replication
CT688_RS16615	COG0359	binds to the 23S rRNA
CT688_RS16620	COG0629	single-stranded DNA binding
CT688_RS16635	COG2319	Wd-40 repeat
CT688_RS16635	COG4249	Peptidase C14 caspase catalytic subunit p20
CT688_RS16650	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CT688_RS16665	COG1260	myo-inositol-1-phosphate synthase
CT688_RS16675	COG2890	protein-(glutamine-N5) methyltransferase activity
CT688_RS16695	COG1473	amidohydrolase
CT688_RS16695	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CT688_RS16705	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CT688_RS16705	COG2308	Evidence 4 Homologs of previously reported genes of
CT688_RS16710	COG2308	Evidence 4 Homologs of previously reported genes of
CT688_RS16710	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CT688_RS16715	COG1024	Enoyl-CoA hydratase
CT688_RS16720	COG1802	Transcriptional regulator
CT688_RS16765	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CT688_RS16780	COG1024	Enoyl-CoA hydratase
CT688_RS16790	COG1024	Enoyl-CoA hydratase
CT688_RS16790	COG1250	3-hydroxyacyl-CoA dehydrogenase
CT688_RS16795	COG0183	Belongs to the thiolase family
CT688_RS16810	COG1012	belongs to the aldehyde dehydrogenase family
CT688_RS16815	COG1960	acyl-CoA dehydrogenase activity
CT688_RS16850	COG3842	ATPase activity
CT688_RS16870	COG0300	oxidoreductase activity
CT688_RS16890	COG0477	Major facilitator Superfamily
CT688_RS16910	COG2267	carboxylic ester hydrolase activity
CT688_RS16920	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS16935	COG2267	carboxylic ester hydrolase activity
CT688_RS16965	COG1028	Short-chain dehydrogenase reductase Sdr
CT688_RS16975	COG0495	leucyl-tRNA aminoacylation
CT688_RS16980	COG2259	Doxx family
CT688_RS17005	COG2149	membrane
CT688_RS17015	COG0596	Alpha beta hydrolase
CT688_RS17040	COG1846	Transcriptional regulator
CT688_RS17045	COG2124	cytochrome p450
CT688_RS17055	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CT688_RS17070	COG2271	Major facilitator Superfamily
CT688_RS17085	COG1678	Uncharacterized ACR, COG1678
CT688_RS17105	COG5650	phosphatidylinositol metabolic process
CT688_RS17110	COG0617	tRNA 3'-terminal CCA addition
CT688_RS17140	COG1595	DNA-templated transcription, initiation
CT688_RS17150	COG3118	belongs to the thioredoxin family
CT688_RS17150	COG0492	ferredoxin-NADP+ reductase activity
CT688_RS17155	COG0860	N-Acetylmuramoyl-L-alanine amidase
CT688_RS17155	COG3409	Peptidoglycan-binding domain 1 protein
CT688_RS17170	COG1192	Involved in chromosome partitioning
CT688_RS17175	COG0357	Ribosomal RNA small subunit methyltransferase G
CT688_RS17185	COG0706	membrane insertase activity
CT688_RS17190	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CT688_RS17195	COG0594	ribonuclease P activity
CT688_RS17200	COG0230	Belongs to the bacterial ribosomal protein bL34 family